## Sat Nov 16 13:03:56 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin22/SRD_1_bin.18.fa -m mmseqs --itype genome -o SRD_1_bin.18 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/SRD_1_bin.18 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRD1_k127_101420_0	452652.KSE_61200	7.858e-159	521.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,2M23P@2063|Kitasatospora	201174|Actinobacteria	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRD1_k127_101420_4	1382306.JNIM01000001_gene772	3.486e-26	121.0	COG0494@1|root,COG0494@2|Bacteria,2G7AT@200795|Chloroflexi	200795|Chloroflexi	L	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRD1_k127_101420_3	383372.Rcas_4088	6.859e-32	134.0	COG2802@1|root,COG2802@2|Bacteria,2G76N@200795|Chloroflexi,375N5@32061|Chloroflexia	32061|Chloroflexia	S	PFAM peptidase S16 lon domain protein	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
SRD1_k127_101420_5	1123279.ATUS01000001_gene1126	7.538e-15	76.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,1SC9F@1236|Gammaproteobacteria,1J6W7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	iscX	GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
SRD1_k127_101420_2	883.DvMF_2816	9.967e-77	265.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,42MA4@68525|delta/epsilon subdivisions,2WIPU@28221|Deltaproteobacteria,2M8CR@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD1_k127_101420_1	1173026.Glo7428_1570	4.799e-101	332.0	COG0605@1|root,COG0605@2|Bacteria,1G0VH@1117|Cyanobacteria	1117|Cyanobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRD1_k127_101420_6	604331.AUHY01000007_gene708	6.646e-09	60.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1WIMD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRD1_k127_1026377_0	1173026.Glo7428_0892	3.188e-80	279.0	28IVI@1|root,2Z8TY@2|Bacteria,1G87H@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
SRD1_k127_1026377_1	1173026.Glo7428_0892	1.592e-56	212.0	28IVI@1|root,2Z8TY@2|Bacteria,1G87H@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
SRD1_k127_1026377_2	521674.Plim_3878	4.477e-08	57.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
SRD1_k127_10320_5	1267534.KB906756_gene712	7.758e-45	175.0	2A3BS@1|root,30RTX@2|Bacteria,3Y943@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_10320_3	489825.LYNGBM3L_63170	2.697e-105	349.0	COG1136@1|root,COG1136@2|Bacteria,1G4IP@1117|Cyanobacteria,1HA7Y@1150|Oscillatoriales	1117|Cyanobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_10320_0	489825.LYNGBM3L_63180	2.117e-211	684.0	COG0577@1|root,COG0577@2|Bacteria,1G0Z7@1117|Cyanobacteria,1H9BF@1150|Oscillatoriales	1117|Cyanobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRD1_k127_10320_1	1173023.KE650771_gene5324	1.616e-111	375.0	COG0845@1|root,COG0845@2|Bacteria,1G29R@1117|Cyanobacteria	1117|Cyanobacteria	M	Rnd family efflux transporter mfp subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
SRD1_k127_10320_7	1121013.P873_09975	1.643e-11	72.0	2EKD9@1|root,33E3J@2|Bacteria,1RIMW@1224|Proteobacteria,1S7IQ@1236|Gammaproteobacteria,1XB6N@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_10320_4	1158050.KB895456_gene2115	1.055e-67	246.0	2C57D@1|root,2Z7RS@2|Bacteria,2GNIJ@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
SRD1_k127_10320_2	1121372.AULK01000005_gene1725	2.945e-108	360.0	COG3817@1|root,COG3817@2|Bacteria,2I9GU@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF979)	-	-	-	-	-	-	-	-	-	-	-	-	DUF979
SRD1_k127_108541_0	253839.SSNG_04458	5.655e-37	156.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF11
SRD1_k127_1088740_0	1121472.AQWN01000003_gene1566	1.882e-161	522.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,2604R@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRD1_k127_1103947_0	298654.FraEuI1c_2968	1.019e-50	186.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4ETN1@85013|Frankiales	201174|Actinobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRD1_k127_1103947_3	485916.Dtox_3100	5.485e-11	70.0	2ATKN@1|root,31J4X@2|Bacteria,1V5JB@1239|Firmicutes,24KI6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1103947_1	1123024.AUII01000003_gene3360	1.276e-34	140.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria,4DYCJ@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_1103947_4	264732.Moth_1842	4.346e-05	52.0	COG5662@1|root,COG5662@2|Bacteria,1VKS6@1239|Firmicutes,24VD1@186801|Clostridia	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRD1_k127_1103947_2	1499967.BAYZ01000185_gene4544	7.532e-13	80.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2092,DUF4367,LolA,LolA_like,MucB_RseB
SRD1_k127_1103997_4	1218075.BAYA01000010_gene3399	3.884e-19	100.0	COG2199@1|root,COG3706@2|Bacteria,1PHVB@1224|Proteobacteria,2W90T@28216|Betaproteobacteria,1KD6I@119060|Burkholderiaceae	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRD1_k127_1103997_2	1121430.JMLG01000004_gene859	6.54e-114	397.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,2609P@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
SRD1_k127_1103997_1	644966.Tmar_0077	2.398e-134	451.0	COG0008@1|root,COG1384@1|root,COG0008@2|Bacteria,COG1384@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3WCIN@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRD1_k127_1103997_3	1869.MB27_02875	2.02e-51	188.0	COG2185@1|root,COG2185@2|Bacteria,2IFJD@201174|Actinobacteria,4DDD4@85008|Micromonosporales	201174|Actinobacteria	I	B12 binding domain	icmB	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRD1_k127_1103997_0	760568.Desku_1207	2.937e-233	735.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,260X7@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM methylmalonyl-CoA mutase N-terminal domain	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRD1_k127_1120789_1	702437.HMPREF9432_01155	2.743e-63	241.0	2DBE5@1|root,2Z8QQ@2|Bacteria,1TPFD@1239|Firmicutes,4H21Z@909932|Negativicutes	909932|Negativicutes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1120789_2	477974.Daud_2096	2.798e-47	192.0	COG2327@1|root,COG2327@2|Bacteria,1TPTI@1239|Firmicutes,248QN@186801|Clostridia,2603G@186807|Peptococcaceae	186801|Clostridia	S	PFAM Polysaccharide pyruvyl transferase	csaB	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,PS_pyruv_trans
SRD1_k127_1120789_0	243164.DET0769	4.114e-64	234.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi,34D00@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRD1_k127_1120789_3	546414.Deide_11660	8.21e-10	62.0	COG0060@1|root,COG0060@2|Bacteria,1WI61@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRD1_k127_1124082_1	1173023.KE650771_gene2025	5.685e-154	519.0	COG5549@1|root,COG5549@2|Bacteria,1G2AK@1117|Cyanobacteria,1JI4Z@1189|Stigonemataceae	1117|Cyanobacteria	O	Domain of unknown function (DUF5118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
SRD1_k127_1124082_0	502025.Hoch_4888	2.1e-322	1003.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WK05@28221|Deltaproteobacteria,2YZMG@29|Myxococcales	28221|Deltaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
SRD1_k127_1124082_4	504728.K649_11975	1.139e-74	271.0	COG1028@1|root,COG1028@2|Bacteria	504728.K649_11975|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1124082_5	504728.K649_11970	3.081e-50	184.0	COG1846@1|root,COG1846@2|Bacteria,1WMZ0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRD1_k127_1124082_3	1122221.JHVI01000003_gene381	8.903e-106	363.0	COG1024@1|root,COG1024@2|Bacteria,1WIYN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD1_k127_1124082_2	94624.Bpet0552	1.004e-134	447.0	COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2VIAN@28216|Betaproteobacteria,3T283@506|Alcaligenaceae	28216|Betaproteobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_1132124_1	635013.TherJR_0933	6.031e-163	551.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,260CZ@186807|Peptococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRD1_k127_1132124_0	868595.Desca_0320	4.379e-177	593.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,260CZ@186807|Peptococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRD1_k127_1132124_2	1267534.KB906755_gene4305	5.357e-06	58.0	COG3386@1|root,COG3386@2|Bacteria,3Y3S3@57723|Acidobacteria,2JIBP@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,NHL
SRD1_k127_1139391_5	67373.JOBF01000027_gene1528	4.576e-27	116.0	COG0119@1|root,COG0119@2|Bacteria	2|Bacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA2	-	2.3.1.182,2.3.3.13,2.3.3.14	ko:K01649,ko:K02594,ko:K09011	ko00290,ko00620,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00271,R01213,R07399	RC00004,RC00067,RC00470,RC01205,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRD1_k127_1139391_9	399549.Msed_1206	0.000828	50.0	COG3794@1|root,arCOG02917@2157|Archaea,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	pcy	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRD1_k127_1139391_3	309799.DICTH_1767	1.913e-38	161.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5,PocR,Response_reg
SRD1_k127_1139391_7	1120973.AQXL01000118_gene504	1.153e-08	63.0	COG1547@1|root,COG1547@2|Bacteria,1V9RH@1239|Firmicutes,4HJA4@91061|Bacilli,27A70@186823|Alicyclobacillaceae	91061|Bacilli	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRD1_k127_1139391_2	263358.VAB18032_26250	4.169e-48	186.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4D9QU@85008|Micromonosporales	201174|Actinobacteria	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	livF	-	-	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRD1_k127_1139391_4	1532557.JL37_03805	8.287e-35	149.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,3T22A@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport systems ATPase component	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRD1_k127_1139391_8	335659.S23_43410	0.0002051	52.0	COG4177@1|root,COG4177@2|Bacteria,1R67B@1224|Proteobacteria,2U0XB@28211|Alphaproteobacteria,3JTTX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD1_k127_1139391_6	710696.Intca_2054	2.599e-18	96.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4FFXG@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD1_k127_1139391_0	235909.GK1598	2.217e-153	503.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HAHB@91061|Bacilli,1WFMX@129337|Geobacillus	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	yngI	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD1_k127_1139391_1	575540.Isop_2916	1.033e-103	349.0	COG0001@1|root,COG0001@2|Bacteria,2IX4X@203682|Planctomycetes	203682|Planctomycetes	H	COG0001 Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_1176702_0	1278073.MYSTI_04368	2.17e-84	291.0	COG4122@1|root,COG4122@2|Bacteria,1R9D7@1224|Proteobacteria,42ZQ8@68525|delta/epsilon subdivisions,2WVSH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRD1_k127_1176702_1	58344.JOEL01000022_gene988	1.028e-78	275.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF11
SRD1_k127_1176702_2	1042877.GQS_01430	8.325e-09	66.0	COG2819@1|root,arCOG07139@2157|Archaea,2XWUG@28890|Euryarchaeota,243X4@183968|Thermococci	183968|Thermococci	S	Starch binding domain	-	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	CBM_20,Esterase
SRD1_k127_1177617_1	485913.Krac_8263	2.631e-155	498.0	COG0626@1|root,COG0626@2|Bacteria,2G5M2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRD1_k127_1177617_0	240292.Ava_4156	5.339e-157	512.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,1G0T4@1117|Cyanobacteria,1HM63@1161|Nostocales	1117|Cyanobacteria	EK	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
SRD1_k127_1177617_4	760568.Desku_1180	3.062e-69	243.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,260A5@186807|Peptococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRD1_k127_1177617_8	1121920.AUAU01000002_gene2058	1.035e-06	61.0	COG0581@1|root,COG0581@2|Bacteria,3Y3JF@57723|Acidobacteria	57723|Acidobacteria	P	Phosphate transport system permease protein PstA	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRD1_k127_1177617_7	935948.KE386493_gene2343	6.172e-07	60.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,42FTA@68295|Thermoanaerobacterales	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRD1_k127_1177617_2	562970.Btus_2535	3.236e-100	337.0	COG0226@1|root,COG0226@2|Bacteria,1TYCT@1239|Firmicutes,4I7GX@91061|Bacilli,279TX@186823|Alicyclobacillaceae	91061|Bacilli	P	Belongs to the PstS family	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRD1_k127_1177617_6	1114959.SZMC14600_11833	6.619e-14	72.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4DY3N@85010|Pseudonocardiales	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRD1_k127_1177617_3	188626.HMPREF0321_1736	4.322e-84	283.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,1ZVN7@145357|Dermacoccaceae	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRD1_k127_1177617_5	316067.Geob_2010	5.607e-65	228.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WMUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM phosphate ABC transporter	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRD1_k127_1224245_1	401526.TcarDRAFT_1875	1.177e-57	214.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD1_k127_1224245_0	457570.Nther_1904	1.12e-68	250.0	COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,24A5F@186801|Clostridia	186801|Clostridia	EG	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRD1_k127_1269489_1	479434.Sthe_2989	5.06e-49	183.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	2|Bacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRD1_k127_1269489_0	502025.Hoch_0564	2.954e-126	417.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2YWB2@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_1280037_1	555079.Toce_0752	2.967e-119	426.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia,42FAA@68295|Thermoanaerobacterales	186801|Clostridia	J	PFAM RNA-binding protein AU-1 Ribonuclease E G	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
SRD1_k127_1280037_4	1121422.AUMW01000011_gene113	9.402e-50	183.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,264WN@186807|Peptococcaceae	186801|Clostridia	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
SRD1_k127_1280037_8	395495.Lcho_4175	6.533e-23	109.0	COG0745@1|root,COG2203@1|root,COG5000@1|root,COG5001@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KJEE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_4,Response_reg
SRD1_k127_1280037_7	429009.Adeg_2095	2.213e-28	124.0	COG2266@1|root,COG2266@2|Bacteria,1UJC9@1239|Firmicutes,25F1Q@186801|Clostridia,42J7N@68295|Thermoanaerobacterales	186801|Clostridia	H	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
SRD1_k127_1280037_6	1089553.Tph_c28380	2.187e-28	127.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,42GD3@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRD1_k127_1280037_2	309799.DICTH_0722	2.105e-103	348.0	COG2805@1|root,COG2805@2|Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRD1_k127_1280037_0	477974.Daud_0009	2.082e-129	420.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,25ZYC@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRD1_k127_1280037_3	1306406.ASHX01000001_gene3698	1.526e-62	220.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRD1_k127_1280037_5	515635.Dtur_0891	5.815e-43	162.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	mcrA	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_4,HNH_5
SRD1_k127_1286517_3	1379698.RBG1_1C00001G0519	2.334e-41	164.0	COG0697@1|root,COG0697@2|Bacteria,2NPZZ@2323|unclassified Bacteria	2|Bacteria	EG	EamA-like transporter family	pagO	-	-	ko:K07790	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.7	-	-	EamA
SRD1_k127_1286517_1	861299.J421_1546	1.014e-80	284.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1ZTKM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	FL	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18
SRD1_k127_1286517_2	1449076.JOOE01000004_gene560	3.062e-52	188.0	2CVTP@1|root,32SY9@2|Bacteria,1N209@1224|Proteobacteria,2UC8J@28211|Alphaproteobacteria,2K5GB@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1203
SRD1_k127_1286517_6	1183438.GKIL_2106	5.502e-19	99.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
SRD1_k127_1286517_0	391625.PPSIR1_21524	7.712e-196	623.0	COG1509@1|root,COG1509@2|Bacteria,1R8HT@1224|Proteobacteria,43DMX@68525|delta/epsilon subdivisions,2X6DS@28221|Deltaproteobacteria,2YUSV@29|Myxococcales	28221|Deltaproteobacteria	E	lysine 2,3-aminomutase	kamA1	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	LAM_C
SRD1_k127_1286517_4	448385.sce5626	2.842e-30	126.0	COG1522@1|root,COG1522@2|Bacteria,1N0DP@1224|Proteobacteria,42W6I@68525|delta/epsilon subdivisions,2WSF8@28221|Deltaproteobacteria,2YW31@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRD1_k127_1289349_6	644966.Tmar_0869	8.949e-53	199.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,3WCJ3@538999|Clostridiales incertae sedis	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRD1_k127_1289349_1	443143.GM18_3886	1.617e-130	432.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRD1_k127_1289349_3	621372.ACIH01000171_gene3899	1.972e-61	222.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,26T5F@186822|Paenibacillaceae	91061|Bacilli	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU15230	FAD_binding_4,MurB_C
SRD1_k127_1289349_2	1537715.JQFJ01000002_gene1154	3.934e-68	243.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2TREC@28211|Alphaproteobacteria,2K0W3@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRD1_k127_1289349_7	264732.Moth_2007	2.184e-36	151.0	COG0546@1|root,COG0546@2|Bacteria,1TPPZ@1239|Firmicutes,24GK6@186801|Clostridia,42GMH@68295|Thermoanaerobacterales	186801|Clostridia	S	HAD-superfamily hydrolase, subfamily IA	Gph	-	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRD1_k127_1289349_9	1121430.JMLG01000008_gene1575	3.844e-21	108.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,24BQ7@186801|Clostridia,26476@186807|Peptococcaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Cu_amine_oxidN1,Peripla_BP_2
SRD1_k127_1289349_4	582515.KR51_00011290	3.583e-61	228.0	COG0025@1|root,COG0025@2|Bacteria,1G1WP@1117|Cyanobacteria	1117|Cyanobacteria	P	TIGRFAM Na H antiporter, bacterial form	-	GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRD1_k127_1289349_5	485913.Krac_8380	5.476e-55	206.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,2G66N@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRD1_k127_1289349_8	1120949.KB903309_gene1115	5.499e-35	136.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4DE65@85008|Micromonosporales	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRD1_k127_1289349_0	760568.Desku_2906	3.394e-230	731.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,2611G@186807|Peptococcaceae	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRD1_k127_1289349_10	1463936.JOJI01000016_gene142	0.0006047	49.0	COG3595@1|root,COG3595@2|Bacteria,2I8IR@201174|Actinobacteria	201174|Actinobacteria	T	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRD1_k127_1299675_0	871968.DESME_15100	7.061e-05	56.0	COG1629@1|root,COG2247@1|root,COG3391@1|root,COG2247@2|Bacteria,COG3391@2|Bacteria,COG4771@2|Bacteria,1V0RA@1239|Firmicutes,24AV7@186801|Clostridia,260Q2@186807|Peptococcaceae	186801|Clostridia	EM	cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Lipase_GDSL_2,TIG
SRD1_k127_1304967_0	221288.JH992901_gene2984	2.521e-147	489.0	COG1282@1|root,COG1282@2|Bacteria,1G2AX@1117|Cyanobacteria,1JHQ2@1189|Stigonemataceae	1117|Cyanobacteria	C	NAD(P) transhydrogenase beta subunit	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRD1_k127_1304967_2	65393.PCC7424_4266	3.315e-24	109.0	COG3288@1|root,COG3288@2|Bacteria,1G711@1117|Cyanobacteria,3KI7E@43988|Cyanothece	1117|Cyanobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntA-2	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRD1_k127_1304967_1	479434.Sthe_1945	1.675e-124	409.0	COG3288@1|root,COG3288@2|Bacteria,2GB86@200795|Chloroflexi,27XYV@189775|Thermomicrobia	189775|Thermomicrobia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRD1_k127_1307097_3	644282.Deba_0755	1.342e-27	118.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2WQQM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRD1_k127_1307097_0	868595.Desca_1069	7.463e-152	506.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,260I6@186807|Peptococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRD1_k127_1307097_2	485913.Krac_8960	1.661e-80	275.0	COG0500@1|root,COG2226@2|Bacteria,2G6R0@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRD1_k127_1307097_1	1382304.JNIL01000001_gene3015	5.358e-136	443.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,4HAKQ@91061|Bacilli,279ER@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
SRD1_k127_1307097_4	525368.HMPREF0591_3856	6.313e-19	94.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria,23AQX@1762|Mycobacteriaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRD1_k127_1315716_8	485913.Krac_8654	5.49e-21	98.0	COG0491@1|root,COG0491@2|Bacteria,2G7QF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRD1_k127_1315716_5	1423321.AS29_10735	4.497e-60	218.0	COG3327@1|root,COG3327@2|Bacteria,1TRBU@1239|Firmicutes,4HCP9@91061|Bacilli,1ZD7Z@1386|Bacillus	91061|Bacilli	K	PaaX-like protein	paaX	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
SRD1_k127_1315716_6	502025.Hoch_5225	1.717e-56	211.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,437U1@68525|delta/epsilon subdivisions,2X33K@28221|Deltaproteobacteria,2YU2K@29|Myxococcales	28221|Deltaproteobacteria	S	benzoyl-CoA oxygenase	-	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
SRD1_k127_1315716_1	1382306.JNIM01000001_gene268	8.401e-110	361.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRD1_k127_1315716_0	1382306.JNIM01000001_gene332	2.674e-112	370.0	COG1788@1|root,COG1788@2|Bacteria,2G6IM@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRD1_k127_1315716_3	1121405.dsmv_2388	9.236e-90	304.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,42R4B@68525|delta/epsilon subdivisions,2WMZN@28221|Deltaproteobacteria,2MHNA@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRD1_k127_1315716_7	485913.Krac_8256	2.708e-51	192.0	COG2095@1|root,COG2095@2|Bacteria,2G938@200795|Chloroflexi	200795|Chloroflexi	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
SRD1_k127_1315716_9	1267533.KB906737_gene2012	0.0002089	49.0	COG1629@1|root,COG4771@2|Bacteria,3Y6HD@57723|Acidobacteria,2JKQR@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRD1_k127_1315716_4	515635.Dtur_1753	3.234e-77	288.0	COG1609@1|root,COG2199@1|root,COG2203@1|root,COG2206@1|root,COG1609@2|Bacteria,COG2199@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	rpfG_3	-	-	ko:K02030,ko:K02103,ko:K02529	-	M00236	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1.3	-	-	GAF_2,GGDEF,HD,HD_5,HisKA_7TM,Peripla_BP_3
SRD1_k127_1315716_2	1382306.JNIM01000001_gene1613	7.43e-99	337.0	COG0247@1|root,COG0247@2|Bacteria,2G5V8@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
SRD1_k127_1317372_0	1242864.D187_000932	3.629e-74	269.0	COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria	1224|Proteobacteria	G	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRD1_k127_1317372_1	1487953.JMKF01000045_gene2870	1.534e-46	176.0	COG1802@1|root,COG1802@2|Bacteria,1G2P5@1117|Cyanobacteria,1HHM7@1150|Oscillatoriales	1117|Cyanobacteria	K	PFAM Bacterial regulatory proteins, gntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRD1_k127_1317372_2	926569.ANT_19690	1.472e-36	150.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRD1_k127_1317699_1	937777.Deipe_3573	4.137e-29	128.0	COG1040@1|root,COG1040@2|Bacteria,1WKB1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRD1_k127_1317699_0	1123250.KB908379_gene1006	4.006e-73	260.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,4H2K8@909932|Negativicutes	909932|Negativicutes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRD1_k127_1365785_6	596327.PORUE0001_1523	1.426e-06	51.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,2FPQ5@200643|Bacteroidia,22WX6@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRD1_k127_1365785_4	1469607.KK073769_gene5049	4.37e-11	71.0	COG0457@1|root,COG0457@2|Bacteria,1G36K@1117|Cyanobacteria,1HQDG@1161|Nostocales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,TPR_1,TPR_11,TPR_2,TPR_8
SRD1_k127_1365785_7	864702.OsccyDRAFT_3762	0.000814	51.0	COG1826@1|root,COG1826@2|Bacteria,1G7W1@1117|Cyanobacteria,1HCWT@1150|Oscillatoriales	1117|Cyanobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRD1_k127_1365785_2	1303518.CCALI_02575	8.34e-26	113.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT,TrbL,VanY
SRD1_k127_1365785_5	891968.Anamo_0857	9.396e-07	57.0	COG2868@1|root,COG2868@2|Bacteria,3TBIX@508458|Synergistetes	508458|Synergistetes	J	Cysteine protease Prp	-	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
SRD1_k127_1365785_3	555079.Toce_0763	5.039e-25	108.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,42GTV@68295|Thermoanaerobacterales	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRD1_k127_1365785_1	555079.Toce_1158	3.263e-43	162.0	COG1586@1|root,COG1586@2|Bacteria,1V3U2@1239|Firmicutes,24H9Q@186801|Clostridia,42GCX@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speH	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10460	AdoMet_dc
SRD1_k127_1365785_0	65093.PCC7418_0875	2.05e-51	189.0	COG0421@1|root,COG0421@2|Bacteria,1G36Y@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Spermine_synt_N,Spermine_synth
SRD1_k127_136682_0	251229.Chro_4925	7.342e-66	234.0	COG0664@1|root,COG0664@2|Bacteria,1G1UQ@1117|Cyanobacteria,3VJMP@52604|Pleurocapsales	1117|Cyanobacteria	K	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
SRD1_k127_136682_1	1380370.JIBA01000012_gene3905	7.979e-09	64.0	COG4409@1|root,COG4409@2|Bacteria,2IDDY@201174|Actinobacteria,4FH84@85021|Intrasporangiaceae	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_14036_2	1227266.HMPREF1551_01121	9.57e-10	69.0	COG4099@1|root,COG4099@2|Bacteria,4NJFP@976|Bacteroidetes,1HX3H@117743|Flavobacteriia,1ER2N@1016|Capnocytophaga	976|Bacteroidetes	S	phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase
SRD1_k127_14036_0	240015.ACP_0487	7.575e-234	760.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_14036_1	234267.Acid_5076	3.661e-126	410.0	COG3285@1|root,COG3285@2|Bacteria,3Y74I@57723|Acidobacteria	57723|Acidobacteria	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRD1_k127_1410621_0	1449049.JONW01000005_gene1515	2.636e-63	241.0	2DVT6@1|root,33X2K@2|Bacteria,1NWQT@1224|Proteobacteria	1224|Proteobacteria	S	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRD1_k127_1410621_1	383372.Rcas_0215	4.518e-05	56.0	COG0457@1|root,COG5635@1|root,COG0457@2|Bacteria,COG5635@2|Bacteria,2G9QS@200795|Chloroflexi	200795|Chloroflexi	T	SMART RNA-processing protein HAT helix repeating-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,TPR_16,TPR_19,TPR_8
SRD1_k127_141108_1	1267535.KB906767_gene1756	4.841e-29	124.0	COG4993@1|root,COG4993@2|Bacteria,3Y2WV@57723|Acidobacteria,2JKWV@204432|Acidobacteriia	204432|Acidobacteriia	G	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ
SRD1_k127_141108_0	401526.TcarDRAFT_1875	8.485e-92	324.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD1_k127_1418359_3	1267534.KB906759_gene1968	2.992e-81	276.0	COG1090@1|root,COG1090@2|Bacteria,3Y2PB@57723|Acidobacteria,2JI82@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRD1_k127_1418359_1	1382356.JQMP01000004_gene188	3.395e-128	421.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,27YSW@189775|Thermomicrobia	189775|Thermomicrobia	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRD1_k127_1418359_0	401526.TcarDRAFT_1656	1.401e-135	454.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4H3C8@909932|Negativicutes	909932|Negativicutes	M	Penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SRD1_k127_1418359_7	1499967.BAYZ01000147_gene720	4.932e-07	62.0	COG2891@1|root,COG2891@2|Bacteria,2NRRJ@2323|unclassified Bacteria	2|Bacteria	M	rod shape-determining protein MreD	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
SRD1_k127_1418359_5	720554.Clocl_1113	2.402e-23	109.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,3WKDC@541000|Ruminococcaceae	186801|Clostridia	M	rod shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRD1_k127_1418359_2	1209989.TepiRe1_1653	3.789e-93	317.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,42EXB@68295|Thermoanaerobacterales	186801|Clostridia	D	TIGRFAM Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRD1_k127_1418359_4	555079.Toce_0738	2.042e-40	158.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,42GIM@68295|Thermoanaerobacterales	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRD1_k127_1418359_6	1123296.JQKE01000019_gene1663	2.469e-12	73.0	COG1463@1|root,COG1463@2|Bacteria,1RHH6@1224|Proteobacteria,2VV58@28216|Betaproteobacteria,2KRVP@206351|Neisseriales	206351|Neisseriales	Q	Protein of unknown function (DUF3465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3465
SRD1_k127_144285_12	411473.RUMCAL_02393	1.718e-17	85.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,3WGDE@541000|Ruminococcaceae	186801|Clostridia	NU	type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRD1_k127_144285_0	1128421.JAGA01000003_gene3456	1.123e-179	572.0	COG2873@1|root,COG2873@2|Bacteria,2NQN4@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	cysD	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SRD1_k127_144285_7	76636.JOEC01000002_gene2527	1.93e-38	151.0	COG1832@1|root,COG1832@2|Bacteria,2IHSP@201174|Actinobacteria,4FMRD@85023|Microbacteriaceae	201174|Actinobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRD1_k127_144285_3	1267533.KB906735_gene4864	1.221e-60	223.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD1_k127_144285_13	383372.Rcas_2749	3.838e-16	92.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_144285_15	573370.DMR_04420	5.847e-09	68.0	COG5305@1|root,COG5305@2|Bacteria,1NZSH@1224|Proteobacteria	1224|Proteobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRD1_k127_144285_16	518766.Rmar_1750	3.299e-05	53.0	COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,4P230@976|Bacteroidetes	2|Bacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,STN,TonB_dep_Rec
SRD1_k127_144285_4	1167006.UWK_02517	2.009e-55	206.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,2MI4K@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRD1_k127_144285_6	1136417.AZWE01000037_gene1125	1.284e-38	161.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4DIGR@85008|Micromonosporales	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRD1_k127_144285_8	1120950.KB892768_gene5342	1.143e-35	139.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4DP6U@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_144285_11	1499683.CCFF01000012_gene1355	4.705e-23	104.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,36EQW@31979|Clostridiaceae	186801|Clostridia	KT	response regulator	srrA1	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_144285_5	35754.JNYJ01000006_gene5226	9.183e-53	201.0	COG1277@1|root,COG1277@2|Bacteria,2GKW6@201174|Actinobacteria,4D96E@85008|Micromonosporales	201174|Actinobacteria	S	Involved in multi-copper enzyme maturation, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRD1_k127_144285_1	309801.trd_1503	2.951e-85	294.0	COG1131@1|root,COG1131@2|Bacteria,2G69S@200795|Chloroflexi,27XTG@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_144285_14	479434.Sthe_2190	2.303e-11	76.0	COG5662@1|root,COG5662@2|Bacteria,2G7G7@200795|Chloroflexi,27YCS@189775|Thermomicrobia	189775|Thermomicrobia	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_144285_10	35754.JNYJ01000006_gene5223	1.977e-23	109.0	COG1595@1|root,COG1595@2|Bacteria,2IG6R@201174|Actinobacteria,4DD4B@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_144285_2	1536772.R70723_25590	1.088e-63	231.0	COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,4HD58@91061|Bacilli,26UDF@186822|Paenibacillaceae	91061|Bacilli	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRD1_k127_144285_9	1395571.TMS3_0107090	1.822e-29	118.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	methyltransferase	sumf2	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRD1_k127_1496111_6	487521.OCU_42800	4.21e-13	70.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria,23AQX@1762|Mycobacteriaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRD1_k127_1496111_0	497964.CfE428DRAFT_4053	5.025e-103	346.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRD1_k127_1496111_3	1179773.BN6_28670	1.654e-25	112.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4E2NI@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRD1_k127_1496111_1	1203602.HMPREF1527_00582	1.035e-62	224.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4CUM2@84998|Coriobacteriia	84998|Coriobacteriia	K	RNA polymerase sigma-70 factor, sigma-B F G subfamily	-	-	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD1_k127_1496111_4	525904.Tter_2629	5.805e-24	103.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRD1_k127_1496111_5	585531.HMPREF0063_12797	2.555e-20	95.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria,4DRS0@85009|Propionibacteriales	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRD1_k127_1496111_2	56110.Oscil6304_5763	3.814e-31	137.0	COG0642@1|root,COG0745@1|root,COG3829@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1G4X8@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRD1_k127_1504546_5	456442.Mboo_2053	4.35e-26	124.0	COG1164@1|root,arCOG04758@2157|Archaea	2157|Archaea	E	oligoendopeptidase F	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
SRD1_k127_1504546_1	28444.JODQ01000010_gene3183	2.331e-69	241.0	KOG2391@1|root,3279X@2|Bacteria,2I3V8@201174|Actinobacteria,4ER48@85012|Streptosporangiales	201174|Actinobacteria	O	protein transport	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1504546_6	309801.trd_A0438	4.149e-25	113.0	2E4KM@1|root,32ZFK@2|Bacteria,2GBAS@200795|Chloroflexi,27YJQ@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRD1_k127_1504546_7	35754.JNYJ01000009_gene1911	2.508e-22	98.0	2B1D5@1|root,31TTS@2|Bacteria,2GSZW@201174|Actinobacteria,4DJGA@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1504546_4	1297570.MESS4_150036	1.05e-27	123.0	COG1028@1|root,COG1028@2|Bacteria,1MXTP@1224|Proteobacteria,2TQST@28211|Alphaproteobacteria,43HWG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	fabG1	-	1.1.1.120,1.1.1.175,1.1.1.48	ko:K22185,ko:K22215	ko00040,ko00052,ko01100,map00040,map00052,map01100	-	R01094,R01097,R01429	RC00066,RC00161	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRD1_k127_1504546_3	1500894.JQNN01000001_gene2744	1.846e-37	152.0	COG0454@1|root,COG1247@1|root,COG0456@2|Bacteria,COG1247@2|Bacteria,1RDHN@1224|Proteobacteria,2VQM1@28216|Betaproteobacteria,474F3@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Acetyltransferase (GNAT) domain	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
SRD1_k127_1504546_2	861299.J421_1764	1.009e-39	154.0	COG1881@1|root,COG1881@2|Bacteria,1ZU1T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRD1_k127_1504546_0	469383.Cwoe_2865	2.305e-71	256.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4CQ48@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRD1_k127_1516756_7	867903.ThesuDRAFT_02387	3.752e-06	49.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,25BTZ@186801|Clostridia	186801|Clostridia	S	PFAM Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRD1_k127_1516756_2	1121468.AUBR01000010_gene2431	2.789e-85	306.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,42EWB@68295|Thermoanaerobacterales	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
SRD1_k127_1516756_5	1267534.KB906754_gene3238	4.096e-22	100.0	COG0736@1|root,COG0736@2|Bacteria,3Y7XF@57723|Acidobacteria,2JN3Q@204432|Acidobacteriia	204432|Acidobacteriia	I	4'-phosphopantetheinyl transferase superfamily	-	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRD1_k127_1516756_4	69014.TK1178	4.92e-26	118.0	COG1913@1|root,arCOG00458@2157|Archaea,2XSVV@28890|Euryarchaeota,243DU@183968|Thermococci	183968|Thermococci	S	zinc metalloprotease whose natural substrate is	amzA	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
SRD1_k127_1516756_6	1379698.RBG1_1C00001G0763	1.607e-16	93.0	COG2885@1|root,COG5276@1|root,COG2885@2|Bacteria,COG5276@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
SRD1_k127_1516756_3	1123288.SOV_4c01730	1.989e-38	164.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4H4EZ@909932|Negativicutes	909932|Negativicutes	L	Hydrolase, NUDIX family	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRD1_k127_1516756_1	867903.ThesuDRAFT_00739	5.587e-165	527.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WCX5@538999|Clostridiales incertae sedis	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRD1_k127_1516756_0	1120973.AQXL01000122_gene149	2.641e-192	615.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,27975@186823|Alicyclobacillaceae	91061|Bacilli	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD1_k127_1547596_0	1128421.JAGA01000002_gene60	8.253e-205	652.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2NNKQ@2323|unclassified Bacteria	2|Bacteria	E	B12 binding domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0030312,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13,2.1.1.245,2.1.1.258	ko:K00197,ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00680,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00357,M00377,M00422	R00946,R02289,R09096,R09365,R10219,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRD1_k127_1574802_0	1382306.JNIM01000001_gene2859	1.125e-11	73.0	COG0589@1|root,COG0589@2|Bacteria,2G7D7@200795|Chloroflexi	200795|Chloroflexi	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRD1_k127_1598889_2	595460.RRSWK_00638	6.846e-85	295.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,2IWZA@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3,ABC_tran
SRD1_k127_1598889_1	661478.OP10G_2908	1.244e-93	317.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	ybhF-C	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRD1_k127_1598889_4	1163617.SCD_n01439	5.95e-33	142.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,2VH7G@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRD1_k127_1598889_0	338963.Pcar_2558	1.85e-141	481.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43TNR@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_9,Response_reg
SRD1_k127_1598889_3	1329516.JPST01000009_gene2087	1.389e-64	228.0	COG0500@1|root,COG2226@2|Bacteria,1V261@1239|Firmicutes,4HI81@91061|Bacilli,27CTA@186824|Thermoactinomycetaceae	91061|Bacilli	Q	O-methyltransferase	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
SRD1_k127_1598889_5	1232410.KI421417_gene2738	3.181e-12	67.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,42URG@68525|delta/epsilon subdivisions,2WNDG@28221|Deltaproteobacteria,43V0S@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	mceE	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRD1_k127_160952_3	1151119.KB895489_gene660	1.381e-36	139.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria	201174|Actinobacteria	M	phospholipase C	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRD1_k127_160952_1	219305.MCAG_00296	1.048e-52	203.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,4DAW3@85008|Micromonosporales	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRD1_k127_160952_2	219305.MCAG_00296	3.306e-48	191.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,4DAW3@85008|Micromonosporales	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRD1_k127_160952_0	1038859.AXAU01000003_gene5921	2.202e-85	290.0	COG0656@1|root,COG0656@2|Bacteria,1MUH2@1224|Proteobacteria,2TTC2@28211|Alphaproteobacteria,3JV6E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Aldo/keto reductase family	MA20_17035	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRD1_k127_160952_4	1379270.AUXF01000002_gene1387	7.792e-10	70.0	COG2091@1|root,COG2091@2|Bacteria,1ZUE3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1620119_1	429009.Adeg_1570	8.676e-108	368.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,42FD0@68295|Thermoanaerobacterales	186801|Clostridia	M	TIGRFAM stage V sporulation protein D	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
SRD1_k127_1620119_0	251221.35214064	2.158e-119	400.0	COG0769@1|root,COG0769@2|Bacteria,1G0HH@1117|Cyanobacteria	1117|Cyanobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRD1_k127_1620119_4	1283287.KB822576_gene3972	9.583e-58	219.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4DNW8@85009|Propionibacteriales	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRD1_k127_1620119_5	370438.PTH_1970	5.495e-43	170.0	COG1478@1|root,COG1478@2|Bacteria,1TSK1@1239|Firmicutes,24E4J@186801|Clostridia,263UE@186807|Peptococcaceae	186801|Clostridia	S	F420-0:Gamma-glutamyl ligase	-	-	-	-	-	-	-	-	-	-	-	-	F420_ligase
SRD1_k127_1620119_3	1449126.JQKL01000021_gene75	1.031e-62	232.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,268KA@186813|unclassified Clostridiales	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRD1_k127_1620119_2	1382359.JIAL01000001_gene1975	4.312e-96	331.0	COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria,2JHQF@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRD1_k127_1620119_6	1111479.AXAR01000004_gene2112	2.045e-22	105.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,277YA@186823|Alicyclobacillaceae	91061|Bacilli	D	Stage V sporulation protein E	spoVE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRD1_k127_1679978_2	649747.HMPREF0083_01337	1.138e-45	178.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,4HB6B@91061|Bacilli,26S37@186822|Paenibacillaceae	91061|Bacilli	J	Metal-dependent phosphoesterase	php	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
SRD1_k127_1679978_1	266117.Rxyl_0967	2.83e-67	234.0	COG0529@1|root,COG0529@2|Bacteria,2GMUK@201174|Actinobacteria,4CTDY@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the synthesis of activated sulfate	-	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
SRD1_k127_1679978_0	525904.Tter_0039	4.59e-134	434.0	COG2046@1|root,COG2046@2|Bacteria,2NNS5@2323|unclassified Bacteria	2|Bacteria	P	PUA-like domain	sat	-	2.7.1.25,2.7.7.4	ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
SRD1_k127_1681845_3	1382306.JNIM01000001_gene141	8.065e-55	207.0	COG1520@1|root,COG2755@1|root,COG3537@1|root,COG1520@2|Bacteria,COG2755@2|Bacteria,COG3537@2|Bacteria,2G7QQ@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 18 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1681845_2	326427.Cagg_1085	2.624e-65	231.0	COG0730@1|root,COG0730@2|Bacteria,2G6RC@200795|Chloroflexi,377UT@32061|Chloroflexia	32061|Chloroflexia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRD1_k127_1681845_1	1463917.JODC01000028_gene923	8.743e-101	346.0	COG4934@1|root,COG4934@2|Bacteria,2IB5Q@201174|Actinobacteria	201174|Actinobacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1681845_4	96561.Dole_2448	3.39e-30	130.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2WQWW@28221|Deltaproteobacteria,2MPV7@213118|Desulfobacterales	28221|Deltaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRD1_k127_1681845_0	246194.CHY_1128	1.849e-152	499.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,42GBR@68295|Thermoanaerobacterales	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD1_k127_1681845_5	321327.CYA_0975	2.741e-21	103.0	COG2372@1|root,COG2948@1|root,COG2372@2|Bacteria,COG2948@2|Bacteria,1G0F5@1117|Cyanobacteria,1H0Z9@1129|Synechococcus	1117|Cyanobacteria	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
SRD1_k127_1703874_4	1183438.GKIL_3293	1.003e-16	88.0	2BFE4@1|root,3297K@2|Bacteria,1G7GW@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1703874_5	1329516.JPST01000020_gene2242	1.775e-07	60.0	arCOG10684@1|root,33EXG@2|Bacteria,1VMXD@1239|Firmicutes,4HYPU@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1453)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1703874_0	1463917.JODC01000014_gene2033	1.445e-54	198.0	COG4312@1|root,COG4312@2|Bacteria,2H9QT@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRD1_k127_1703874_2	1502851.FG93_05451	2.31e-28	122.0	COG3832@1|root,COG3832@2|Bacteria,1RI3S@1224|Proteobacteria,2UB60@28211|Alphaproteobacteria,3JXJH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRD1_k127_1703874_3	105425.BBPL01000009_gene1396	1.744e-26	115.0	COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria,2NJYJ@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRD1_k127_1703874_1	1459636.NTE_00646	7.396e-44	163.0	COG3324@1|root,arCOG04946@2157|Archaea,41T3T@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
SRD1_k127_1703874_6	1283299.AUKG01000005_gene149	0.0005006	48.0	2AX06@1|root,31NY6@2|Bacteria,2HRF3@201174|Actinobacteria,4CTDP@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
SRD1_k127_1732780_0	1144275.COCOR_05937	1.389e-84	290.0	COG2746@1|root,COG2746@2|Bacteria,1R68C@1224|Proteobacteria	1224|Proteobacteria	V	aminoglycoside	aacC	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
SRD1_k127_1732780_1	1229172.JQFA01000002_gene2629	8.329e-41	173.0	COG1074@1|root,COG1074@2|Bacteria,1G4R0@1117|Cyanobacteria,1HE61@1150|Oscillatoriales	1117|Cyanobacteria	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRD1_k127_1734122_8	2754.EH55_04425	4.229e-20	105.0	COG1663@1|root,COG4370@1|root,COG1663@2|Bacteria,COG4370@2|Bacteria,3T9ZA@508458|Synergistetes	508458|Synergistetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
SRD1_k127_1734122_7	1536773.R70331_09895	3.55e-22	112.0	COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,26TF3@186822|Paenibacillaceae	91061|Bacilli	F	Belongs to the 5'-nucleotidase family	yunD	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Metallophos
SRD1_k127_1734122_6	221359.RS9916_34242	5.244e-39	160.0	COG0763@1|root,COG0763@2|Bacteria,1G0V6@1117|Cyanobacteria,1GYVI@1129|Synechococcus	1117|Cyanobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
SRD1_k127_1734122_1	373903.Hore_17550	6.289e-80	275.0	COG1043@1|root,COG1043@2|Bacteria,1TQRI@1239|Firmicutes,24EGS@186801|Clostridia,3WAIK@53433|Halanaerobiales	186801|Clostridia	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
SRD1_k127_1734122_4	484770.UFO1_4224	4.799e-44	176.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4H4C3@909932|Negativicutes	909932|Negativicutes	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRD1_k127_1734122_3	316067.Geob_2315	6.154e-64	229.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2WJ4I@28221|Deltaproteobacteria,43S89@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535,ko:K13599	ko00540,ko01100,ko02020,map00540,map01100,map02020	M00060,M00498	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005,ko02022	-	-	-	LpxC
SRD1_k127_1734122_2	574087.Acear_2197	1.269e-76	269.0	COG1044@1|root,COG1044@2|Bacteria,1TP7W@1239|Firmicutes,24HJW@186801|Clostridia,3WACF@53433|Halanaerobiales	186801|Clostridia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
SRD1_k127_1734122_12	1069080.KB913028_gene73	1.521e-05	52.0	COG2825@1|root,COG2825@2|Bacteria,1V8QT@1239|Firmicutes,4H4RJ@909932|Negativicutes	909932|Negativicutes	M	outer membrane chaperone Skp (OmpH)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SRD1_k127_1734122_10	1069080.KB913028_gene75	1.874e-08	66.0	COG2825@1|root,COG2825@2|Bacteria,1V95M@1239|Firmicutes,4H4RT@909932|Negativicutes	909932|Negativicutes	M	PFAM Outer membrane chaperone Skp (OmpH)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SRD1_k127_1734122_5	1122216.AUHW01000017_gene1180	1.386e-43	182.0	COG4775@1|root,COG4775@2|Bacteria,1UMDS@1239|Firmicutes,4H27F@909932|Negativicutes	909932|Negativicutes	M	Outer membrane protein, OMP85 family	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRD1_k127_1734122_9	1123229.AUBC01000016_gene4318	1.705e-12	83.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,3JVNT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	tamB	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
SRD1_k127_1734122_0	857293.CAAU_1996	8.777e-258	818.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,36DYE@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRD1_k127_1734122_11	1125863.JAFN01000001_gene1680	8.491e-06	57.0	COG5512@1|root,COG5512@2|Bacteria,1N6KK@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRD1_k127_1744982_5	1123405.AUMM01000016_gene2460	6.86e-12	72.0	COG0671@1|root,COG0671@2|Bacteria,1VARM@1239|Firmicutes,4HN1F@91061|Bacilli	91061|Bacilli	I	COG0671 Membrane-associated phospholipid phosphatase	bcrC	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRD1_k127_1744982_3	525904.Tter_1695	1.025e-44	171.0	COG0822@1|root,COG0822@2|Bacteria,2NPXN@2323|unclassified Bacteria	2|Bacteria	C	NifU-like N terminal domain	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRD1_k127_1744982_1	1128421.JAGA01000002_gene1806	3.155e-155	505.0	COG0520@1|root,COG0520@2|Bacteria,2NNS0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRD1_k127_1744982_4	886293.Sinac_5289	1.107e-22	104.0	COG2146@1|root,COG2146@2|Bacteria,2J13Z@203682|Planctomycetes	203682|Planctomycetes	C	of nitrite reductase and ring-hydroxylating	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRD1_k127_1744982_2	266117.Rxyl_0168	1.05e-60	224.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CQXR@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRD1_k127_1744982_0	1379698.RBG1_1C00001G0736	1.157e-222	699.0	COG0719@1|root,COG0719@2|Bacteria,2NNKT@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRD1_k127_1753972_1	235985.BBPN01000040_gene354	7.599e-72	259.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,2NKRD@228398|Streptacidiphilus	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRD1_k127_1753972_3	926560.KE387023_gene1119	3.245e-51	193.0	COG0789@1|root,COG0789@2|Bacteria,1WMUY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRD1_k127_1753972_0	479434.Sthe_3502	2.279e-89	311.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi,27XF7@189775|Thermomicrobia	2|Bacteria	C	Proline dehydrogenase	-	GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046983,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRD1_k127_1753972_2	1469245.JFBG01000009_gene573	1.639e-70	250.0	COG0329@1|root,COG0329@2|Bacteria,1MXM5@1224|Proteobacteria	1224|Proteobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRD1_k127_1753972_4	1121124.JNIX01000001_gene1039	4.116e-46	175.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
SRD1_k127_1753972_5	1385520.N802_12355	2.115e-34	134.0	COG0809@1|root,COG0809@2|Bacteria,2GN51@201174|Actinobacteria,4FEK5@85021|Intrasporangiaceae	201174|Actinobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRD1_k127_1754164_1	485918.Cpin_5064	2.8e-20	106.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,1IPZT@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRD1_k127_1754164_0	1382359.JIAL01000001_gene2494	8.196e-52	190.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD1_k127_1756907_4	204669.Acid345_0208	4.035e-30	133.0	COG4219@1|root,COG4219@2|Bacteria,3Y5D9@57723|Acidobacteria,2JM59@204432|Acidobacteriia	204432|Acidobacteriia	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1756907_3	246197.MXAN_0189	2.961e-30	139.0	COG4219@1|root,COG4219@2|Bacteria,1PJ0I@1224|Proteobacteria	1224|Proteobacteria	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	DUF3313,Peptidase_M23,Peptidase_M56,TonB_C
SRD1_k127_1756907_1	1340493.JNIF01000003_gene2366	5.347e-32	129.0	COG3682@1|root,COG3682@2|Bacteria,3Y4ZW@57723|Acidobacteria	57723|Acidobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRD1_k127_1756907_2	926560.KE387027_gene633	1.405e-31	135.0	COG1917@1|root,COG3832@1|root,COG1917@2|Bacteria,COG3832@2|Bacteria,1WN52@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD1_k127_1756907_0	485913.Krac_4425	7.568e-83	299.0	COG0451@1|root,COG0451@2|Bacteria,2G9SG@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRD1_k127_1756907_5	485913.Krac_2223	2.407e-10	71.0	arCOG10517@1|root,31Y5Z@2|Bacteria,2G8TN@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1756907_6	68223.JNZY01000005_gene3989	3.311e-06	58.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,2GMNT@201174|Actinobacteria	201174|Actinobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3,PD40,TAT_signal
SRD1_k127_1760493_2	1173028.ANKO01000221_gene586	3.411e-118	400.0	COG1139@1|root,COG1139@2|Bacteria,1GC4K@1117|Cyanobacteria,1HF15@1150|Oscillatoriales	1117|Cyanobacteria	C	Pfam:DUF162	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,LUD_dom
SRD1_k127_1760493_5	953739.SVEN_6651	4.924e-72	251.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria	201174|Actinobacteria	C	Fe-S oxidoreductase	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
SRD1_k127_1760493_0	479434.Sthe_0989	3.41e-136	461.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	189775|Thermomicrobia	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRD1_k127_1760493_17	1348662.CARG_08240	1.79e-12	76.0	COG2259@1|root,COG2259@2|Bacteria,2IQEY@201174|Actinobacteria,22NGM@1653|Corynebacteriaceae	201174|Actinobacteria	S	DoxX family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX,MauE
SRD1_k127_1760493_16	266117.Rxyl_0031	1.464e-12	77.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,4CQ9G@84995|Rubrobacteria	84995|Rubrobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRD1_k127_1760493_13	903818.KI912269_gene369	2.291e-34	138.0	COG3762@1|root,COG3762@2|Bacteria	2|Bacteria	S	Membrane	Z012_08985	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRD1_k127_1760493_10	903818.KI912269_gene368	2.962e-42	166.0	COG1512@1|root,COG1512@2|Bacteria,3Y4JT@57723|Acidobacteria	57723|Acidobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRD1_k127_1760493_4	903818.KI912269_gene367	9.381e-73	250.0	COG1704@1|root,COG1704@2|Bacteria,3Y4QG@57723|Acidobacteria	57723|Acidobacteria	S	PFAM LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRD1_k127_1760493_11	1162668.LFE_0953	2.422e-38	153.0	2CH9R@1|root,33MNW@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRD1_k127_1760493_14	68219.JNXI01000018_gene7157	5.501e-30	132.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria	201174|Actinobacteria	I	Diacylglycerol kinase	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
SRD1_k127_1760493_1	1048834.TC41_0707	1.962e-129	427.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,278YJ@186823|Alicyclobacillaceae	91061|Bacilli	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	iYO844.BSU04360	Nramp
SRD1_k127_1760493_12	1451189.CFAL_08365	4.523e-36	146.0	COG1321@1|root,COG1321@2|Bacteria,2GK7P@201174|Actinobacteria,22M5J@1653|Corynebacteriaceae	201174|Actinobacteria	K	Mn-dependent transcriptional regulator	mntR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRD1_k127_1760493_15	1203566.HMPREF1285_00609	7.349e-22	105.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,22N7F@1653|Corynebacteriaceae	201174|Actinobacteria	P	Belongs to the Fur family	furB	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRD1_k127_1760493_7	479434.Sthe_2975	1.863e-70	259.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi,27XKB@189775|Thermomicrobia	189775|Thermomicrobia	P	ABC 3 transport family	-	-	-	ko:K09819	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
SRD1_k127_1760493_6	479434.Sthe_2976	2.073e-71	261.0	COG1121@1|root,COG1121@2|Bacteria,2G7X2@200795|Chloroflexi,27XH6@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K09820	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
SRD1_k127_1760493_8	562970.Btus_2410	6.173e-61	222.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,278FS@186823|Alicyclobacillaceae	91061|Bacilli	P	Belongs to the bacterial solute-binding protein 9 family	adcA	-	-	ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZinT,ZnuA
SRD1_k127_1760493_9	1385510.N781_15615	1.563e-43	169.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,2YAEU@289201|Pontibacillus	91061|Bacilli	M	Lytic transglycosylase	yjbJ	-	-	-	-	-	-	-	-	-	-	-	SLT
SRD1_k127_1760493_3	1249634.D781_3942	2.297e-76	277.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,404KW@613|Serratia	1236|Gammaproteobacteria	NU	ATP synthase alpha/beta family, beta-barrel domain	hrcN	-	3.6.3.14	ko:K03224	ko03070,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.6.1,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
SRD1_k127_1760493_18	1380354.JIAN01000012_gene3611	5.281e-12	78.0	COG1766@1|root,COG1766@2|Bacteria,2HG9F@201174|Actinobacteria,4F1MY@85016|Cellulomonadaceae	201174|Actinobacteria	N	Flagellar M-ring protein C-terminal	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
SRD1_k127_179705_0	240015.ACP_0487	1.975e-180	592.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_181260_1	1297617.JPJD01000002_gene2704	7.874e-29	124.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,268ZM@186813|unclassified Clostridiales	186801|Clostridia	K	MraZ protein, putative antitoxin-like	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRD1_k127_181260_0	309801.trd_0056	1.783e-70	249.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,27XI5@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	-	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRD1_k127_181260_2	1536772.R70723_24590	0.0001796	50.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,26S7A@186822|Paenibacillaceae	91061|Bacilli	M	Stage V sporulation protein d	spoVD	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
SRD1_k127_1833546_1	861299.J421_4352	2.756e-59	218.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	yecE	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRD1_k127_1833546_0	1128421.JAGA01000002_gene614	7.098e-72	257.0	COG1194@1|root,COG1194@2|Bacteria,2NPAU@2323|unclassified Bacteria	2|Bacteria	L	endonuclease III	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
SRD1_k127_1833546_2	635013.TherJR_2368	6.051e-54	195.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,261ID@186807|Peptococcaceae	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRD1_k127_1840481_2	742743.HMPREF9453_00655	1.059e-05	53.0	COG0810@1|root,COG0810@2|Bacteria,1VDCH@1239|Firmicutes,4H54A@909932|Negativicutes	909932|Negativicutes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRD1_k127_1840481_0	497964.CfE428DRAFT_0631	1.159e-155	527.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRD1_k127_1923733_0	1242864.D187_002508	1.719e-49	183.0	COG3177@1|root,COG3177@2|Bacteria,1MX0V@1224|Proteobacteria,42RKK@68525|delta/epsilon subdivisions,2WNV3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRD1_k127_1923733_1	1410613.JNKF01000013_gene2680	1.205e-08	68.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,4NFZQ@976|Bacteroidetes,2FN03@200643|Bacteroidia	976|Bacteroidetes	L	DNA-dependent ATPase I and helicase II	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRD1_k127_1923733_2	1157637.KB892113_gene5094	2.163e-05	58.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria	201174|Actinobacteria	L	DNA helicase	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
SRD1_k127_193617_0	1469245.JFBG01000019_gene1125	0.0	1131.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1WXI8@135613|Chromatiales	135613|Chromatiales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
SRD1_k127_1992785_0	1121430.JMLG01000002_gene1008	2.006e-273	867.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,25ZYN@186807|Peptococcaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRD1_k127_1992785_1	1463917.JODC01000008_gene3233	4.162e-114	377.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD1_k127_2008748_4	278963.ATWD01000002_gene823	5.384e-05	51.0	COG0457@1|root,COG0457@2|Bacteria,3Y59I@57723|Acidobacteria,2JJNP@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2008748_5	1122603.ATVI01000005_gene2944	0.0002177	44.0	COG1397@1|root,COG1397@2|Bacteria,1N4A8@1224|Proteobacteria,1T8J7@1236|Gammaproteobacteria,1XATR@135614|Xanthomonadales	135614|Xanthomonadales	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2008748_2	1122132.AQYH01000010_gene4059	9.702e-12	70.0	COG5642@1|root,COG5642@2|Bacteria,1NAEY@1224|Proteobacteria,2U6F6@28211|Alphaproteobacteria,4BH9G@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
SRD1_k127_2008748_1	1173020.Cha6605_6264	3.053e-30	125.0	COG5654@1|root,COG5654@2|Bacteria,1G7GA@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM RES domain	-	-	-	-	-	-	-	-	-	-	-	-	RES
SRD1_k127_2008748_0	1336243.JAEA01000011_gene3207	3.453e-90	303.0	COG0654@1|root,COG0654@2|Bacteria,1P1NX@1224|Proteobacteria,2TRZX@28211|Alphaproteobacteria,1JTU0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRD1_k127_2028066_0	1123321.KB905825_gene76	7.143e-37	146.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add2	GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.4.4,3.5.4.40	ko:K01488,ko:K18286	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRD1_k127_2028066_1	1121382.JQKG01000066_gene2631	1.06e-34	141.0	COG1321@1|root,COG1321@2|Bacteria,1WIR2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRD1_k127_205168_1	1120972.AUMH01000017_gene757	6.266e-38	149.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,2781N@186823|Alicyclobacillaceae	91061|Bacilli	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
SRD1_k127_205168_2	1401067.HMPREF0872_06650	8.585e-05	53.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4H55U@909932|Negativicutes	909932|Negativicutes	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
SRD1_k127_205168_0	696369.KI912183_gene2524	2.802e-133	443.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,260XD@186807|Peptococcaceae	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRD1_k127_2053483_0	398511.BpOF4_06365	2.297e-22	109.0	COG0103@1|root,COG2340@1|root,COG0103@2|Bacteria,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4HJ21@91061|Bacilli,1ZDSK@1386|Bacillus	91061|Bacilli	J	protein with SCP PR1 domains	ykwD	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
SRD1_k127_2059611_4	926566.Terro_4339	9.384e-05	47.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,3Y43Q@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,NHL
SRD1_k127_2059611_3	1242864.D187_003107	1.395e-16	85.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WRBN@28221|Deltaproteobacteria,2Z0B0@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRD1_k127_2059611_2	326423.RBAM_007360	2.903e-20	98.0	COG1846@1|root,COG1846@2|Bacteria,1VIXS@1239|Firmicutes,4HPYM@91061|Bacilli	91061|Bacilli	K	helix_turn_helix multiple antibiotic resistance protein	yetL	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	MarR
SRD1_k127_2059611_1	861299.J421_2436	6.902e-63	232.0	COG1566@1|root,COG1566@2|Bacteria,1ZT4J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Biotin-lipoyl like	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3
SRD1_k127_2059611_0	1183438.GKIL_4333	7.305e-110	374.0	COG0477@1|root,COG2814@2|Bacteria,1GQDW@1117|Cyanobacteria	1117|Cyanobacteria	U	drug resistance transporter, EmrB QacA subfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
SRD1_k127_2117144_1	234267.Acid_7336	4.531e-118	405.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria	57723|Acidobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRD1_k127_2117144_0	1123508.JH636441_gene3449	8.585e-154	493.0	COG1233@1|root,COG1233@2|Bacteria,2IX17@203682|Planctomycetes	203682|Planctomycetes	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRD1_k127_2118325_1	338963.Pcar_0238	2.661e-63	243.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1NPFY@1224|Proteobacteria,42PRW@68525|delta/epsilon subdivisions,2WIMG@28221|Deltaproteobacteria,43SUD@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methylenetetrahydrofolate reductase	metF-2	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0504	MTHFR,S-methyl_trans
SRD1_k127_2118325_2	1254432.SCE1572_31355	3.726e-53	210.0	COG2362@1|root,COG2362@2|Bacteria,1QH4F@1224|Proteobacteria,42UEA@68525|delta/epsilon subdivisions,2WQVJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
SRD1_k127_2118325_3	484770.UFO1_4296	4.745e-48	186.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4H3T7@909932|Negativicutes	909932|Negativicutes	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRD1_k127_2118325_8	583345.Mmol_2174	5.54e-07	62.0	COG1463@1|root,COG1463@2|Bacteria,1RHH6@1224|Proteobacteria,2VV58@28216|Betaproteobacteria,2KN6Y@206350|Nitrosomonadales	206350|Nitrosomonadales	Q	Protein of unknown function (DUF3465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3465
SRD1_k127_2118325_4	483219.LILAB_17690	1.35e-36	152.0	COG2887@1|root,COG2887@2|Bacteria,1QXTW@1224|Proteobacteria,43C6C@68525|delta/epsilon subdivisions,2X7GI@28221|Deltaproteobacteria,2YZ5R@29|Myxococcales	28221|Deltaproteobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRD1_k127_2118325_9	443255.SCLAV_p0346	9.255e-07	59.0	COG1051@1|root,COG1051@2|Bacteria,2IG0R@201174|Actinobacteria	201174|Actinobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRD1_k127_2118325_10	649831.L083_5318	0.000179	51.0	2FJMA@1|root,34BAM@2|Bacteria,2IBW2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4760
SRD1_k127_2118325_5	1095769.CAHF01000006_gene1947	4.502e-17	87.0	COG5528@1|root,COG5528@2|Bacteria,1RF9N@1224|Proteobacteria	1224|Proteobacteria	S	Predicted integral membrane protein (DUF2269)	mchD	-	-	-	-	-	-	-	-	-	-	-	DUF2269
SRD1_k127_2118325_0	457570.Nther_2188	7.964e-114	389.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRD1_k127_2118325_6	1321781.HMPREF1985_00528	3.013e-12	76.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4H2TB@909932|Negativicutes	909932|Negativicutes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRD1_k127_2118325_7	502025.Hoch_5725	8.32e-10	68.0	COG0389@1|root,COG0389@2|Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	imuB	-	2.7.7.7	ko:K02346,ko:K14161	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS
SRD1_k127_2136437_0	1386089.N865_01600	3.979e-115	377.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRD1_k127_2136437_1	518766.Rmar_1784	5.558e-95	321.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,4NFTI@976|Bacteroidetes,1FITQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRD1_k127_2137227_6	1157632.AQWQ01000001_gene5378	1.988e-22	101.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_11,Methyltransf_12,PP-binding,Thioesterase
SRD1_k127_2137227_3	1242864.D187_007381	3.287e-37	151.0	COG2091@1|root,COG2091@2|Bacteria,1MZHC@1224|Proteobacteria,42SJT@68525|delta/epsilon subdivisions,2WP3F@28221|Deltaproteobacteria,2YURW@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRD1_k127_2137227_2	861299.J421_0471	1.153e-64	232.0	COG2010@1|root,COG2010@2|Bacteria,1ZUJA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2137227_4	485913.Krac_9564	5.407e-25	116.0	COG3548@1|root,COG3548@2|Bacteria	2|Bacteria	S	protein homotetramerization	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
SRD1_k127_2137227_1	1089544.KB912942_gene1864	3.322e-117	395.0	COG2234@1|root,COG2234@2|Bacteria,2IDP0@201174|Actinobacteria,4DZ4R@85010|Pseudonocardiales	201174|Actinobacteria	E	PA domain	-	-	3.4.11.15	ko:K01264	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28
SRD1_k127_2137227_5	335543.Sfum_0506	1.185e-23	112.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
SRD1_k127_2137227_0	1131814.JAFO01000001_gene3315	0.0	2153.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,3EYBF@335928|Xanthobacteraceae	28211|Alphaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	ndvB	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.321	ko:K13688,ko:K18786	-	-	R10832	RC00397	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
SRD1_k127_2159704_1	479435.Kfla_5459	6.725e-80	278.0	COG3469@1|root,COG3469@2|Bacteria,2GKNC@201174|Actinobacteria,4DW4H@85009|Propionibacteriales	201174|Actinobacteria	G	Glycosyl hydrolases family 18	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_18
SRD1_k127_2159704_3	953739.SVEN_0085	2.172e-37	158.0	COG1572@1|root,COG1572@2|Bacteria,2GKNI@201174|Actinobacteria	201174|Actinobacteria	Q	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5122,HemolysinCabind
SRD1_k127_2159704_6	693661.Arcve_2078	7.689e-11	69.0	COG2010@1|root,arCOG06111@2157|Archaea,2XXGW@28890|Euryarchaeota,2469C@183980|Archaeoglobi	183980|Archaeoglobi	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
SRD1_k127_2159704_2	861299.J421_6089	2.937e-53	206.0	COG1073@1|root,COG1680@1|root,COG1073@2|Bacteria,COG1680@2|Bacteria,1ZU86@142182|Gemmatimonadetes	2|Bacteria	V	Domain of unknown function (DUF3471)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Beta-lactamase,DUF3471,Hydrolase_4
SRD1_k127_2159704_7	883067.HMPREF9237_00669	0.0009356	49.0	COG0640@1|root,COG0640@2|Bacteria,2GUVX@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRD1_k127_2159704_5	1379698.RBG1_1C00001G0763	3.296e-29	132.0	COG2885@1|root,COG5276@1|root,COG2885@2|Bacteria,COG5276@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
SRD1_k127_2159704_4	382464.ABSI01000013_gene1532	2.136e-33	151.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,NACHT,NB-ARC,WD40
SRD1_k127_2159704_0	1118054.CAGW01000014_gene284	2.261e-133	438.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,4HANM@91061|Bacilli,26S9B@186822|Paenibacillaceae	91061|Bacilli	V	MatE	yoeA	-	-	-	-	-	-	-	-	-	-	-	MatE
SRD1_k127_2160104_2	1254432.SCE1572_38000	1.695e-141	455.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,437V1@68525|delta/epsilon subdivisions,2X34I@28221|Deltaproteobacteria,2YU7X@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_2160104_3	1267534.KB906754_gene3511	9.003e-130	436.0	COG0258@1|root,COG0258@2|Bacteria,3Y2FG@57723|Acidobacteria	57723|Acidobacteria	L	5'-3' exonuclease, N-terminal resolvase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRD1_k127_2160104_12	479433.Caci_2811	1.256e-43	161.0	COG0640@1|root,COG0640@2|Bacteria,2IQQU@201174|Actinobacteria	201174|Actinobacteria	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRD1_k127_2160104_14	1268072.PSAB_08865	2.478e-36	142.0	COG3832@1|root,COG3832@2|Bacteria,1V8CU@1239|Firmicutes,4HK29@91061|Bacilli,26WT4@186822|Paenibacillaceae	91061|Bacilli	S	Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRD1_k127_2160104_13	47763.JNZA01000035_gene2560	3.729e-38	151.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria	201174|Actinobacteria	H	bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRD1_k127_2160104_0	562970.Btus_0928	2.602e-260	811.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,4H9NH@91061|Bacilli,2782U@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRD1_k127_2160104_1	879212.DespoDRAFT_01938	7.082e-158	513.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,42MST@68525|delta/epsilon subdivisions,2WKAN@28221|Deltaproteobacteria,2MIWB@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRD1_k127_2160104_4	1121472.AQWN01000015_gene1344	2.7e-116	390.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,260XX@186807|Peptococcaceae	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
SRD1_k127_2160104_11	1121428.DESHY_60189___1	2.856e-45	178.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,261QH@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRD1_k127_2160104_15	401526.TcarDRAFT_0221	7.824e-33	143.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4H4EK@909932|Negativicutes	909932|Negativicutes	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRD1_k127_2160104_7	429009.Adeg_1146	2.903e-63	236.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,42FFX@68295|Thermoanaerobacterales	186801|Clostridia	IJM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
SRD1_k127_2160104_9	324602.Caur_1855	6.546e-52	201.0	COG0142@1|root,COG0142@2|Bacteria,2G6BM@200795|Chloroflexi,3755H@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRD1_k127_2160104_6	697284.ERIC2_c35460	3.369e-69	267.0	COG4346@1|root,COG5650@1|root,COG4346@2|Bacteria,COG5650@2|Bacteria,1TSHX@1239|Firmicutes,4ISHD@91061|Bacilli,26SCF@186822|Paenibacillaceae	91061|Bacilli	O	Glycosyl transferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	F5_F8_type_C,GT87,PMT,PMT_2,PMT_4TMC
SRD1_k127_2160104_8	309801.trd_0619	2.332e-61	223.0	COG0463@1|root,COG0463@2|Bacteria,2G6TA@200795|Chloroflexi,27XT0@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD1_k127_2160104_5	498761.HM1_1824	1.299e-70	248.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia	186801|Clostridia	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRD1_k127_2160104_16	580327.Tthe_1520	9.12e-14	84.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRD1_k127_2160104_10	639282.DEFDS_2125	1.449e-47	186.0	COG0036@1|root,COG0036@2|Bacteria,2GEJ9@200930|Deferribacteres	200930|Deferribacteres	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRD1_k127_2164313_11	105425.BBPL01000040_gene3460	3.992e-15	84.0	COG3291@1|root,COG4870@1|root,COG3291@2|Bacteria,COG4870@2|Bacteria,2I4QS@201174|Actinobacteria,2NN64@228398|Streptacidiphilus	201174|Actinobacteria	O	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF346
SRD1_k127_2164313_12	545693.BMQ_5109	5.642e-14	75.0	COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,4HNPJ@91061|Bacilli,1ZJ2S@1386|Bacillus	91061|Bacilli	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
SRD1_k127_2164313_10	1121440.AUMA01000008_gene830	7.341e-27	122.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42QBH@68525|delta/epsilon subdivisions,2WISQ@28221|Deltaproteobacteria,2MB3A@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	AAA domain	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,Phage_tail_X
SRD1_k127_2164313_5	485913.Krac_6502	2.131e-62	228.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,LTD,PKD,Pro-kuma_activ,fn3
SRD1_k127_2164313_0	1089548.KI783301_gene681	7.724e-107	353.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,3WDY5@539002|Bacillales incertae sedis	91061|Bacilli	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRD1_k127_2164313_7	926550.CLDAP_41110	3.442e-53	194.0	COG0264@1|root,COG0264@2|Bacteria,2G6MJ@200795|Chloroflexi	200795|Chloroflexi	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRD1_k127_2164313_1	1242864.D187_008870	3.332e-100	332.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,2Z0R9@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRD1_k127_2164313_6	485916.Dtox_3210	4.642e-62	220.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,261N9@186807|Peptococcaceae	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRD1_k127_2164313_3	264732.Moth_1038	4.822e-84	288.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,42F7X@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRD1_k127_2164313_9	1246445.ANAY01000013_gene161	3.937e-32	138.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,4EHUH@85012|Streptosporangiales	201174|Actinobacteria	S	Cytidylyltransferase family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRD1_k127_2164313_2	1120973.AQXL01000128_gene2819	1.243e-93	333.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,2788P@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRD1_k127_2164313_4	373903.Hore_07740	1.451e-73	261.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,3WAGW@53433|Halanaerobiales	186801|Clostridia	M	PDZ domain (Also known as DHR or GLGF)	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
SRD1_k127_2164313_8	485916.Dtox_3202	1.275e-39	155.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,260R0@186807|Peptococcaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
SRD1_k127_2178717_2	268407.PWYN_26880	9.116e-21	96.0	COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli,26Z2N@186822|Paenibacillaceae	91061|Bacilli	M	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07900	DAGK_prokar
SRD1_k127_2178717_1	498761.HM1_2448	8.182e-22	104.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia	186801|Clostridia	F	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
SRD1_k127_2178717_0	562970.Btus_0771	3.419e-86	296.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,2785Z@186823|Alicyclobacillaceae	91061|Bacilli	T	AAA domain	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRD1_k127_2208935_4	1125863.JAFN01000001_gene3393	2.072e-69	257.0	COG1232@1|root,COG1232@2|Bacteria,1R0KQ@1224|Proteobacteria,42NBG@68525|delta/epsilon subdivisions,2WKMN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemY	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRD1_k127_2208935_3	225117.XP_009361617.1	5.089e-73	267.0	COG0276@1|root,KOG1321@2759|Eukaryota,37IBX@33090|Viridiplantae,3GA7G@35493|Streptophyta,4JMY8@91835|fabids	35493|Streptophyta	H	Catalyzes the ferrous insertion into protoporphyrin IX	-	GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRD1_k127_2208935_2	502025.Hoch_5896	6.101e-98	338.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2WJZK@28221|Deltaproteobacteria,2YTSB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
SRD1_k127_2208935_1	706434.HMPREF9429_01378	2.409e-163	524.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4H2F2@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRD1_k127_2208935_0	240015.ACP_2455	4.674e-182	580.0	COG0499@1|root,COG0499@2|Bacteria,3Y2J2@57723|Acidobacteria,2JIFV@204432|Acidobacteriia	204432|Acidobacteriia	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRD1_k127_2208935_5	883112.HMPREF9707_01565	9.503e-22	104.0	COG3404@1|root,COG3404@2|Bacteria,1V1X8@1239|Firmicutes,4HI58@91061|Bacilli,27F0U@186827|Aerococcaceae	91061|Bacilli	E	Formiminotransferase-cyclodeaminase	fchA	-	4.3.1.4	ko:K01746	ko00670,ko01100,map00670,map01100	-	R02302	RC00688	ko00000,ko00001,ko01000	-	-	-	FTCD_C
SRD1_k127_2208935_6	1265313.HRUBRA_00701	9.702e-12	70.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,1J5I0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRD1_k127_222263_1	1094715.CM001373_gene3313	4.318e-24	109.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1JDPB@118969|Legionellales	118969|Legionellales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRD1_k127_222263_0	1120919.AUBI01000001_gene3230	2.825e-101	349.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2JWUV@204441|Rhodospirillales	204441|Rhodospirillales	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRD1_k127_2250911_0	1120950.KB892773_gene1095	5.71e-220	697.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DPXV@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRD1_k127_2278773_5	1122223.KB890692_gene3022	6.265e-18	94.0	COG0477@1|root,COG2814@2|Bacteria,1WJCM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRD1_k127_2278773_4	555088.DealDRAFT_2585	1.985e-21	104.0	COG0746@1|root,COG0746@2|Bacteria,1V4AK@1239|Firmicutes,249SR@186801|Clostridia	186801|Clostridia	H	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
SRD1_k127_2278773_1	765420.OSCT_2960	2.401e-58	221.0	COG2890@1|root,COG2890@2|Bacteria,2G8FJ@200795|Chloroflexi,3768E@32061|Chloroflexia	32061|Chloroflexia	J	RNA cap guanine-N2 methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_15
SRD1_k127_2278773_0	1382306.JNIM01000001_gene1813	1.518e-92	333.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRD1_k127_2278773_3	292459.STH1935	1.35e-36	152.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,24AKE@186801|Clostridia	186801|Clostridia	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRD1_k127_2278773_6	1470591.BW41_02809	0.0004185	47.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRD1_k127_2278773_2	32049.SYNPCC7002_A0637	1.103e-44	179.0	COG4206@1|root,COG4206@2|Bacteria,1GHEN@1117|Cyanobacteria,1H4CF@1129|Synechococcus	1117|Cyanobacteria	H	TonB-dependent Receptor Plug Domain	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
SRD1_k127_2280041_0	1121918.ARWE01000001_gene386	1.189e-199	641.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRD1_k127_2280041_1	1172179.AUKV01000007_gene3054	5.938e-15	85.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
SRD1_k127_2288318_0	405948.SACE_1244	1.849e-80	276.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4E5A4@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRD1_k127_2288318_3	278963.ATWD01000001_gene3401	2.575e-25	111.0	2DMEF@1|root,32QYK@2|Bacteria,3Y516@57723|Acidobacteria,2JJEQ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2288318_2	1411123.JQNH01000001_gene807	6.524e-26	118.0	COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,2U5A4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
SRD1_k127_2288318_4	1123258.AQXZ01000014_gene5030	8.23e-19	99.0	COG1835@1|root,COG1835@2|Bacteria,2GP6W@201174|Actinobacteria,4FXPS@85025|Nocardiaceae	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRD1_k127_2288318_1	215803.DB30_1747	2.593e-54	210.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	MA20_04930	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRD1_k127_2292838_0	1131814.JAFO01000001_gene3315	0.0	1131.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,3EYBF@335928|Xanthobacteraceae	28211|Alphaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	ndvB	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.321	ko:K13688,ko:K18786	-	-	R10832	RC00397	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
SRD1_k127_2292838_2	484770.UFO1_0393	2.792e-92	329.0	COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,4H1VG@909932|Negativicutes	909932|Negativicutes	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRD1_k127_2292838_4	1397528.Q671_16195	3.734e-80	277.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1XHSS@135619|Oceanospirillales	135619|Oceanospirillales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_2292838_3	880072.Desac_2860	4.41e-81	285.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_2292838_7	439235.Dalk_2024	1.837e-42	173.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,42R8A@68525|delta/epsilon subdivisions,2WM6Z@28221|Deltaproteobacteria,2MJGT@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
SRD1_k127_2292838_6	861299.J421_3013	5.058e-65	230.0	COG1926@1|root,COG1926@2|Bacteria	2|Bacteria	Q	phosphoribosyltransferase	minD	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Erythro_esteras,Pribosyltran
SRD1_k127_2292838_5	1385935.N836_06990	5.457e-69	241.0	COG0412@1|root,COG0412@2|Bacteria,1G1CY@1117|Cyanobacteria,1HB6M@1150|Oscillatoriales	1117|Cyanobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRD1_k127_2292838_1	1173024.KI912151_gene2146	1.677e-179	572.0	COG2312@1|root,COG2312@2|Bacteria,1GA2Z@1117|Cyanobacteria,1JKPG@1189|Stigonemataceae	1117|Cyanobacteria	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
SRD1_k127_2292838_8	1434325.AZQN01000003_gene2052	4.233e-30	123.0	COG3548@1|root,COG3548@2|Bacteria,4NPIF@976|Bacteroidetes,47R96@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRD1_k127_2311762_2	266835.14026250	7.776e-25	110.0	COG4454@1|root,COG4454@2|Bacteria,1N1PE@1224|Proteobacteria,2UCWF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SoxE
SRD1_k127_2311762_0	189753.AXAS01000012_gene4337	1.292e-68	244.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
SRD1_k127_2311762_1	1165096.ARWF01000001_gene1373	4.637e-38	145.0	COG4319@1|root,COG4319@2|Bacteria,1NCYK@1224|Proteobacteria,2W4CQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRD1_k127_231206_0	1173027.Mic7113_0198	1.784e-89	311.0	COG0410@1|root,COG0410@2|Bacteria,1G1TN@1117|Cyanobacteria,1H996@1150|Oscillatoriales	1117|Cyanobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRD1_k127_231206_2	1532557.JL37_03805	3.879e-85	293.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,3T22A@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport systems ATPase component	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRD1_k127_231206_1	1382306.JNIM01000001_gene1701	2.404e-89	304.0	COG4177@1|root,COG4177@2|Bacteria,2G6D8@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD1_k127_2350815_1	944480.ATUV01000001_gene1220	5.788e-17	89.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,42WCF@68525|delta/epsilon subdivisions,2WRES@28221|Deltaproteobacteria,2M7BM@213113|Desulfurellales	28221|Deltaproteobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
SRD1_k127_2350815_0	1449126.JQKL01000003_gene1744	7.626e-99	337.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,267S1@186813|unclassified Clostridiales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRD1_k127_2389872_7	702437.HMPREF9432_01686	2.771e-46	178.0	COG1127@1|root,COG1127@2|Bacteria,1UGV0@1239|Firmicutes,4H251@909932|Negativicutes	909932|Negativicutes	Q	ABC transporter, ATP-binding protein	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRD1_k127_2389872_4	1122947.FR7_1546	2.78e-52	199.0	COG0767@1|root,COG0767@2|Bacteria,1U95A@1239|Firmicutes,4H2EU@909932|Negativicutes	909932|Negativicutes	Q	Belongs to the MlaE permease family	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRD1_k127_2389872_3	717606.PaecuDRAFT_3788	3.977e-96	321.0	COG0689@1|root,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,4HBH3@91061|Bacilli,26RZT@186822|Paenibacillaceae	91061|Bacilli	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ham1p_like,RNase_PH,RNase_PH_C
SRD1_k127_2389872_0	767817.Desgi_0609	1.59e-202	648.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,2608Z@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRD1_k127_2389872_5	246194.CHY_1488	6.36e-49	182.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,42ENR@68295|Thermoanaerobacterales	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRD1_k127_2389872_8	357808.RoseRS_3600	5.166e-40	170.0	COG1293@1|root,COG1293@2|Bacteria,2G5TC@200795|Chloroflexi,375AD@32061|Chloroflexia	32061|Chloroflexia	K	Fibronectin-binding A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
SRD1_k127_2389872_2	648996.Theam_1729	1.033e-99	338.0	COG0809@1|root,COG0809@2|Bacteria,2G3KG@200783|Aquificae	200783|Aquificae	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRD1_k127_2389872_6	243230.DR_0572	4.746e-48	196.0	COG2385@1|root,COG2385@2|Bacteria,1WJB9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	PFAM Stage II sporulation	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
SRD1_k127_2389872_1	555778.Hneap_0531	2.3e-119	395.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1WWB3@135613|Chromatiales	135613|Chromatiales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRD1_k127_2394998_1	1303518.CCALI_01189	4.668e-52	191.0	COG1459@1|root,COG1459@2|Bacteria	2|Bacteria	U	protein transport across the cell outer membrane	pilC	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
SRD1_k127_2394998_0	1303518.CCALI_01190	4.748e-125	409.0	COG2805@1|root,COG2805@2|Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRD1_k127_2394998_2	1382306.JNIM01000001_gene2709	3.678e-09	69.0	2DBIT@1|root,2Z9GU@2|Bacteria	2|Bacteria	S	Carotene biosynthesis associated membrane protein	mptA	GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K14337,ko:K14339	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	GT87
SRD1_k127_2394998_3	1303518.CCALI_00435	2.912e-06	58.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
SRD1_k127_2398789_0	1382306.JNIM01000001_gene3777	1.041e-139	479.0	COG2303@1|root,COG2303@2|Bacteria,2G7EB@200795|Chloroflexi	200795|Chloroflexi	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
SRD1_k127_2398789_2	518766.Rmar_0183	5.733e-85	290.0	COG0506@1|root,COG0506@2|Bacteria,4NKZB@976|Bacteroidetes,1FJ33@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRD1_k127_2398789_1	1121104.AQXH01000001_gene1571	3.125e-136	448.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRD1_k127_241074_0	401526.TcarDRAFT_0605	2.503e-141	477.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H1X4@909932|Negativicutes	909932|Negativicutes	D	FtsK SpoIIIE family protein	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRD1_k127_241074_1	1144275.COCOR_00242	4.791e-80	283.0	COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,1R49D@1224|Proteobacteria	1224|Proteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRD1_k127_247749_0	272134.KB731326_gene333	1.934e-39	159.0	COG3182@1|root,COG3182@2|Bacteria,1G2SQ@1117|Cyanobacteria,1HAS2@1150|Oscillatoriales	1117|Cyanobacteria	S	Peptidase M4, propeptide, PepSY	-	-	-	-	-	-	-	-	-	-	-	-	PepSY,PepSY_TM
SRD1_k127_247749_2	1366050.N234_19350	3.722e-24	110.0	COG4315@1|root,COG4315@2|Bacteria,1MZC6@1224|Proteobacteria,2VU7D@28216|Betaproteobacteria,1K96M@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRD1_k127_2483007_0	1042156.CXIVA_06460	4.14e-42	167.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,36DUZ@31979|Clostridiaceae	186801|Clostridia	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRD1_k127_2483007_1	927677.ALVU02000001_gene1334	7.239e-32	135.0	COG3548@1|root,COG3548@2|Bacteria,1G8WP@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1211)	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
SRD1_k127_2483007_2	7739.XP_002603850.1	9.179e-07	55.0	2CXS7@1|root,2RZCN@2759|Eukaryota,3A054@33154|Opisthokonta,3BPGU@33208|Metazoa,3D7RG@33213|Bilateria,48JK6@7711|Chordata	33208|Metazoa	T	ShK toxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Ig_3,ShK,Zona_pellucida
SRD1_k127_2509464_0	1382306.JNIM01000001_gene3727	7.542e-38	157.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	ko:K08677	-	-	-	-	ko00000,ko01002	-	-	-	He_PIG,Peptidase_S8,Pro-kuma_activ
SRD1_k127_2509464_1	357808.RoseRS_0063	1.844e-20	101.0	COG3063@1|root,COG3629@1|root,COG3899@1|root,COG3063@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G7ZN@200795|Chloroflexi,377XV@32061|Chloroflexia	32061|Chloroflexia	K	PFAM transcriptional regulator domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
SRD1_k127_2567214_3	1378168.N510_02639	3.246e-06	57.0	COG0103@1|root,COG5492@1|root,COG0103@2|Bacteria,COG5492@2|Bacteria,1TS8J@1239|Firmicutes	1239|Firmicutes	N	COG COG3291 FOG PKD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,fn3
SRD1_k127_2567214_0	1321781.HMPREF1985_01437	3.818e-51	194.0	COG1351@1|root,COG1351@2|Bacteria,1TRAA@1239|Firmicutes,4H2TS@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
SRD1_k127_2567214_2	357808.RoseRS_0760	1.205e-27	119.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi,375V3@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DnaJ
SRD1_k127_2567214_1	760568.Desku_3385	8.954e-29	132.0	COG0845@1|root,COG0845@2|Bacteria,1V2JZ@1239|Firmicutes,24A5A@186801|Clostridia,261XD@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_D23
SRD1_k127_2567229_1	511051.CSE_12590	8.677e-06	57.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR_6,Cu_amine_oxidN1,PSII_BNR,RicinB_lectin_2,Sortilin-Vps10
SRD1_k127_2567229_0	760568.Desku_3373	7.375e-10	66.0	COG4632@1|root,COG4632@2|Bacteria,1TQBV@1239|Firmicutes,25BWD@186801|Clostridia,2674Y@186807|Peptococcaceae	186801|Clostridia	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,NAGPA
SRD1_k127_2600108_4	446468.Ndas_1013	1.106e-09	61.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,4EMHA@85012|Streptosporangiales	201174|Actinobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRD1_k127_2600108_3	1173028.ANKO01000078_gene3873	9.707e-36	145.0	COG0494@1|root,COG0494@2|Bacteria,1G60V@1117|Cyanobacteria,1HAPZ@1150|Oscillatoriales	1117|Cyanobacteria	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRD1_k127_2600108_1	1120973.AQXL01000060_gene2660	1.302e-81	280.0	COG0555@1|root,COG0555@2|Bacteria,1UHZE@1239|Firmicutes,4ITKM@91061|Bacilli	91061|Bacilli	O	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018,ko:K15496	ko02010,map02010	M00189,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.5,3.A.1.8	-	-	BPD_transp_1
SRD1_k127_2600108_0	1120973.AQXL01000060_gene2659	1.968e-91	313.0	COG3842@1|root,COG3842@2|Bacteria,1TQ18@1239|Firmicutes,4HD4K@91061|Bacilli	91061|Bacilli	E	abc transporter atp-binding protein	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
SRD1_k127_2600108_2	1120973.AQXL01000060_gene2659	1.862e-75	261.0	COG3842@1|root,COG3842@2|Bacteria,1TQ18@1239|Firmicutes,4HD4K@91061|Bacilli	91061|Bacilli	E	abc transporter atp-binding protein	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
SRD1_k127_262505_4	1121422.AUMW01000010_gene1038	7.761e-68	245.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,260BZ@186807|Peptococcaceae	186801|Clostridia	O	PDZ domain (Also known as DHR or GLGF)	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin,Trypsin_2
SRD1_k127_262505_9	880073.Calab_0651	1.31e-14	89.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SRD1_k127_262505_2	1123023.JIAI01000019_gene2270	9.93e-85	287.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4DXK6@85010|Pseudonocardiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_262505_5	1117379.BABA_14627	1.319e-54	210.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HATE@91061|Bacilli,1ZDCS@1386|Bacillus	91061|Bacilli	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRD1_k127_262505_6	1449126.JQKL01000018_gene3255	2.362e-48	194.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,2688J@186813|unclassified Clostridiales	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRD1_k127_262505_8	91464.S7335_3563	3.503e-17	96.0	COG0845@1|root,COG0845@2|Bacteria,1G01U@1117|Cyanobacteria,1GZ64@1129|Synechococcus	1117|Cyanobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
SRD1_k127_262505_11	1458275.AZ34_14425	9.483e-05	55.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,4AADJ@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139,ko:K18323	ko01501,ko02020,ko02024,map01501,map02020,map02024	M00642,M00643,M00645,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2,2.A.6.2.41	-	-	OEP
SRD1_k127_262505_1	646529.Desaci_3047	2.251e-97	334.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRD1_k127_262505_7	1480694.DC28_12390	1.934e-30	124.0	COG1725@1|root,COG1725@2|Bacteria,2J9B8@203691|Spirochaetes	203691|Spirochaetes	K	transcriptional regulator	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRD1_k127_262505_0	1121430.JMLG01000001_gene2128	1.288e-191	614.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,2601W@186807|Peptococcaceae	186801|Clostridia	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRD1_k127_262505_3	1121422.AUMW01000013_gene1457	1.49e-84	289.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,260U6@186807|Peptococcaceae	186801|Clostridia	EP	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRD1_k127_262505_10	1278073.MYSTI_08090	5.181e-09	59.0	COG1680@1|root,COG1729@1|root,COG1680@2|Bacteria,COG1729@2|Bacteria,1R49D@1224|Proteobacteria	1224|Proteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
SRD1_k127_2628041_2	1358423.N180_03220	2.466e-24	104.0	COG2936@1|root,COG2936@2|Bacteria,4NHJU@976|Bacteroidetes,1IWV4@117747|Sphingobacteriia	976|Bacteroidetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRD1_k127_2628041_1	1352941.M877_28280	6.226e-129	417.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria	201174|Actinobacteria	K	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRD1_k127_2628041_0	478741.JAFS01000002_gene538	9.765e-168	534.0	COG1063@1|root,COG1063@2|Bacteria,46SZR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRD1_k127_2632855_0	525904.Tter_0363	9.535e-128	423.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	mmgA	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU24170	Thiolase_C,Thiolase_N
SRD1_k127_2632855_1	866895.HBHAL_4640	1.867e-84	288.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HA2A@91061|Bacilli,3NENC@45667|Halobacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	mmgC	-	-	ko:K18244	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_2639681_7	1382359.JIAL01000001_gene92	1.119e-09	70.0	COG0845@1|root,COG0845@2|Bacteria,3Y3C9@57723|Acidobacteria,2JIN9@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
SRD1_k127_2639681_5	411471.SUBVAR_04013	5.72e-46	184.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,25EVD@186801|Clostridia,3WSNF@541000|Ruminococcaceae	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRD1_k127_2639681_3	1121447.JONL01000007_gene1152	4.319e-64	228.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria,2M9HT@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	response regulator, receiver	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_2639681_0	401526.TcarDRAFT_1875	1.208e-110	379.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD1_k127_2639681_1	1265505.ATUG01000001_gene4538	2.141e-91	318.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria,2MI42@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRD1_k127_2639681_2	1123072.AUDH01000006_gene3259	2.119e-65	237.0	COG2041@1|root,COG2041@2|Bacteria,1MWZK@1224|Proteobacteria,2TTCH@28211|Alphaproteobacteria,2JQCT@204441|Rhodospirillales	204441|Rhodospirillales	S	COG2041 Sulfite oxidase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRD1_k127_2639681_4	1283299.AUKG01000001_gene1499	7.361e-54	197.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria,4CQ70@84995|Rubrobacteria	84995|Rubrobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SRD1_k127_2639681_8	1000565.METUNv1_01993	6.316e-05	52.0	COG2104@1|root,COG2104@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiS	GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149,ko:K03154	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
SRD1_k127_2639681_6	335543.Sfum_1822	5.072e-34	133.0	COG0502@1|root,COG0502@2|Bacteria,1MXK0@1224|Proteobacteria,42M3U@68525|delta/epsilon subdivisions,2WJQ6@28221|Deltaproteobacteria,2MRHC@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Biotin and Thiamin Synthesis associated domain	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
SRD1_k127_2646274_0	682795.AciX8_4283	5.071e-120	394.0	COG1063@1|root,COG1063@2|Bacteria,3Y3KU@57723|Acidobacteria,2JIQ4@204432|Acidobacteriia	204432|Acidobacteriia	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD1_k127_2646274_1	404589.Anae109_2930	1.038e-104	362.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2YU40@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRD1_k127_2646274_5	485913.Krac_5622	1.658e-42	157.0	COG5207@1|root,COG5207@2|Bacteria	2|Bacteria	O	Pfam Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N,zf-UBP
SRD1_k127_2646274_3	1227739.Hsw_2761	6.667e-72	255.0	28HGI@1|root,2Z7SC@2|Bacteria,4NJUF@976|Bacteroidetes,47PDE@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2646274_4	1382359.JIAL01000001_gene2460	5.868e-57	218.0	COG1680@1|root,COG1680@2|Bacteria,3Y3DY@57723|Acidobacteria,2JHVC@204432|Acidobacteriia	204432|Acidobacteriia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRD1_k127_2646274_2	661478.OP10G_1792	1.603e-74	270.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRD1_k127_265134_0	62928.azo2212	5.932e-247	771.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2VHYR@28216|Betaproteobacteria,2KV6J@206389|Rhodocyclales	206389|Rhodocyclales	F	COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B	-	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRD1_k127_2653853_2	649747.HMPREF0083_02300	0.0001171	52.0	COG1286@1|root,COG1286@2|Bacteria,1V7U0@1239|Firmicutes,4HIUU@91061|Bacilli,26XZ8@186822|Paenibacillaceae	91061|Bacilli	S	Colicin V production protein	yshB	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
SRD1_k127_2653853_0	273068.TTE1688	4.12e-128	442.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,42F4K@68295|Thermoanaerobacterales	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
SRD1_k127_2653853_1	631362.Thi970DRAFT_04623	1.117e-99	337.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1WXAD@135613|Chromatiales	135613|Chromatiales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRD1_k127_2661046_1	1123288.SOV_1c11860	7.905e-116	404.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,4H2W2@909932|Negativicutes	909932|Negativicutes	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
SRD1_k127_2661046_4	331869.BAL199_01909	9.634e-28	128.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,2TS13@28211|Alphaproteobacteria,4BPYD@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
SRD1_k127_2661046_2	290633.GOX1531	3.211e-45	175.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,2TT93@28211|Alphaproteobacteria,2JQM5@204441|Rhodospirillales	204441|Rhodospirillales	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
SRD1_k127_2661046_8	1121949.AQXT01000002_gene1838	2.141e-06	53.0	COG1886@1|root,COG1886@2|Bacteria,1NMYT@1224|Proteobacteria,2UKAQ@28211|Alphaproteobacteria,4409H@69657|Hyphomonadaceae	28211|Alphaproteobacteria	NU	Type III flagellar switch regulator (C-ring) FliN C-term	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
SRD1_k127_2661046_7	557598.LHK_00441	2.89e-09	68.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,2VH7A@28216|Betaproteobacteria,2KQU5@206351|Neisseriales	206351|Neisseriales	N	flagellar basal-body rod protein FlgG	-	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
SRD1_k127_2661046_5	765420.OSCT_0264	1.314e-26	126.0	COG0652@1|root,COG0652@2|Bacteria,2G69B@200795|Chloroflexi,375JG@32061|Chloroflexia	32061|Chloroflexia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRD1_k127_2661046_6	304371.MCP_1740	8.046e-25	107.0	COG3729@1|root,arCOG11115@2157|Archaea	2157|Archaea	S	general stress protein B in uncultured methanogenic archaeon (Q0W564)	-	-	-	-	-	-	-	-	-	-	-	-	KGG
SRD1_k127_2661046_0	868595.Desca_1853	4.615e-140	456.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,260A0@186807|Peptococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD1_k127_2661046_3	330214.NIDE0989	5.285e-45	177.0	COG0358@1|root,COG0358@2|Bacteria,3J0IN@40117|Nitrospirae	40117|Nitrospirae	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_4,Toprim_N,zf-CHC2
SRD1_k127_2675051_4	306281.AJLK01000033_gene1517	1.731e-30	128.0	COG1670@1|root,COG1670@2|Bacteria,1G6BV@1117|Cyanobacteria,1JM95@1189|Stigonemataceae	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRD1_k127_2675051_0	1123386.AUIW01000002_gene1244	1.95e-216	684.0	COG1012@1|root,COG1012@2|Bacteria,1WJFH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD1_k127_2675051_2	1316936.K678_02820	1.84e-128	426.0	COG0531@1|root,COG0531@2|Bacteria,1NQTH@1224|Proteobacteria,2TUFW@28211|Alphaproteobacteria,2JRZT@204441|Rhodospirillales	204441|Rhodospirillales	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
SRD1_k127_2675051_1	1382356.JQMP01000001_gene1281	3.276e-154	511.0	COG0160@1|root,COG0160@2|Bacteria,2G7XB@200795|Chloroflexi,27Z3E@189775|Thermomicrobia	189775|Thermomicrobia	E	Aminotransferase class-III	-	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_2675051_3	1118054.CAGW01000009_gene3934	9.991e-121	402.0	COG1231@1|root,COG1231@2|Bacteria,1VM1Q@1239|Firmicutes,4HS2U@91061|Bacilli,26WD3@186822|Paenibacillaceae	91061|Bacilli	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRD1_k127_2712861_0	317936.Nos7107_3600	3.432e-48	182.0	COG1670@1|root,COG1670@2|Bacteria,1G5HU@1117|Cyanobacteria,1HIMS@1161|Nostocales	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRD1_k127_2712861_1	1283283.ATXA01000020_gene1338	2.659e-24	108.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria,4EW7K@85013|Frankiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRD1_k127_2712861_3	1234364.AMSF01000061_gene2084	3.406e-16	93.0	COG0793@1|root,COG0793@2|Bacteria,1N4T9@1224|Proteobacteria,1SE36@1236|Gammaproteobacteria,1X70X@135614|Xanthomonadales	135614|Xanthomonadales	M	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ_2
SRD1_k127_2712861_4	485917.Phep_0001	3.572e-06	60.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1IQVH@117747|Sphingobacteriia	976|Bacteroidetes	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
SRD1_k127_2712861_2	1235457.C404_24995	2.656e-20	93.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,2VSHI@28216|Betaproteobacteria,1K79N@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4437)	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2,DUF4437
SRD1_k127_2724310_1	391623.TERMP_02032	4.378e-99	335.0	COG1759@1|root,arCOG04346@2157|Archaea,2XUFR@28890|Euryarchaeota,243GC@183968|Thermococci	183968|Thermococci	F	Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates	purP	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
SRD1_k127_2724310_0	374847.Kcr_0401	3.442e-100	338.0	COG1759@1|root,arCOG04346@2157|Archaea	2157|Archaea	F	Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates	purP	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
SRD1_k127_2724310_2	1380346.JNIH01000003_gene2114	0.0005311	42.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRD1_k127_2751891_1	391587.KAOT1_07713	4.653e-19	102.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HWM8@117743|Flavobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRD1_k127_2751891_0	1382359.JIAL01000001_gene1362	3.984e-114	384.0	COG1793@1|root,COG1793@2|Bacteria,3Y3AP@57723|Acidobacteria,2JIGV@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRD1_k127_2752352_0	401526.TcarDRAFT_1879	0.0	1078.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4H2HF@909932|Negativicutes	1239|Firmicutes	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRD1_k127_2752352_1	1123072.AUDH01000010_gene3487	1.846e-56	204.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2TR3W@28211|Alphaproteobacteria,2JPGJ@204441|Rhodospirillales	204441|Rhodospirillales	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRD1_k127_279778_0	1088868.CIN_04580	7.329e-63	229.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2JWUV@204441|Rhodospirillales	204441|Rhodospirillales	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRD1_k127_279778_2	1183377.Py04_0352	5.81e-41	165.0	COG0047@1|root,arCOG00102@2157|Archaea,2XTPA@28890|Euryarchaeota,242RG@183968|Thermococci	183968|Thermococci	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRD1_k127_279778_1	314345.SPV1_07621	3.34e-49	187.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria	1224|Proteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K03767,ko:K03768,ko:K09565	ko01503,ko04020,ko04022,ko04217,ko05012,ko05016,ko05145,map01503,map04020,map04022,map04217,map05012,map05016,map05145	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRD1_k127_279778_3	243159.AFE_2005	1.095e-31	126.0	COG0693@1|root,COG0693@2|Bacteria,1N8N6@1224|Proteobacteria,1S32P@1236|Gammaproteobacteria,2NBWH@225057|Acidithiobacillales	225057|Acidithiobacillales	K	DJ-1/PfpI family	-	-	4.2.1.103	ko:K18199	ko00930,map00930	-	R05771	RC01467	ko00000,ko00001,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRD1_k127_2801886_2	316055.RPE_0607	1.56e-42	161.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
SRD1_k127_2801886_0	398767.Glov_2399	1.768e-81	279.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,43V8M@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRD1_k127_2801886_1	909663.KI867150_gene1130	2.38e-58	213.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42R04@68525|delta/epsilon subdivisions,2WMZ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM ATPase, BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRD1_k127_2824227_9	1121365.AQXB01000001_gene958	1.797e-18	94.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,22N00@1653|Corynebacteriaceae	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRD1_k127_2824227_12	635013.TherJR_2049	9.53e-15	79.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,262RX@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRD1_k127_2824227_8	555079.Toce_1066	4.494e-21	108.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,42GTF@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRD1_k127_2824227_1	867903.ThesuDRAFT_00298	3.456e-86	290.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3WCDI@538999|Clostridiales incertae sedis	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRD1_k127_2824227_2	429009.Adeg_1417	5.104e-74	253.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,42FGH@68295|Thermoanaerobacterales	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRD1_k127_2824227_7	429009.Adeg_0959	4.236e-28	114.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,42H5S@68295|Thermoanaerobacterales	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRD1_k127_2824227_3	351627.Csac_1605	2.49e-66	245.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,42F9Z@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM Short-chain dehydrogenase reductase SDR	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD1_k127_2824227_4	1235815.BAIX01000034_gene1989	5.516e-52	198.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,2FM9P@200643|Bacteroidia	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRD1_k127_2824227_0	44251.PDUR_13550	9.841e-114	376.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,26QJP@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRD1_k127_2824227_10	644966.Tmar_0944	1.721e-16	81.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,3WCP9@538999|Clostridiales incertae sedis	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRD1_k127_2824227_13	1444309.JAQG01000008_gene1693	9.964e-15	81.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,4HM44@91061|Bacilli,26UF3@186822|Paenibacillaceae	91061|Bacilli	S	metal-binding, possibly nucleic acid-binding protein	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRD1_k127_2824227_6	263358.VAB18032_00105	1.753e-39	165.0	COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria,4D9ZI@85008|Micromonosporales	201174|Actinobacteria	T	Belongs to the peptidase S16 family	lon	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
SRD1_k127_2824227_11	429009.Adeg_0114	1.448e-15	88.0	COG1193@1|root,COG1193@2|Bacteria,1UHZ5@1239|Firmicutes,25E7T@186801|Clostridia,42GTB@68295|Thermoanaerobacterales	186801|Clostridia	L	negative regulation of DNA recombination	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2824227_5	498761.HM1_2154	1.885e-49	183.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRD1_k127_2884312_0	706587.Desti_0512	1.012e-36	146.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,42SPA@68525|delta/epsilon subdivisions,2WPPE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRD1_k127_2884312_1	1382358.JHVN01000036_gene3206	6.566e-24	112.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,21V1A@150247|Anoxybacillus	91061|Bacilli	K	Helix-turn-helix domain	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_2884312_3	1232427.CAVS020000031_gene797	6.775e-05	53.0	COG5660@1|root,COG5660@2|Bacteria,2IGFN@201174|Actinobacteria,22M75@1653|Corynebacteriaceae	201174|Actinobacteria	S	Integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRD1_k127_2884312_2	246197.MXAN_3961	9.259e-12	78.0	COG4796@1|root,COG4796@2|Bacteria,1QX5J@1224|Proteobacteria,4310N@68525|delta/epsilon subdivisions,2WWI7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Type ii and iii secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2884943_1	861299.J421_6282	1.735e-55	205.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
SRD1_k127_2884943_2	477641.MODMU_0154	4.19e-32	145.0	COG0477@1|root,COG0477@2|Bacteria,2GKQH@201174|Actinobacteria,4ETTK@85013|Frankiales	201174|Actinobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1,Sugar_tr
SRD1_k127_2884943_0	357808.RoseRS_0224	1.621e-77	265.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,375H6@32061|Chloroflexia	32061|Chloroflexia	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRD1_k127_2958209_0	266117.Rxyl_1075	6.191e-42	161.0	COG4448@1|root,COG4448@2|Bacteria,2GJA7@201174|Actinobacteria	201174|Actinobacteria	E	L-asparaginase II	ansA	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRD1_k127_2958209_1	1128421.JAGA01000002_gene1062	1.52e-11	75.0	COG5180@1|root,COG5180@2|Bacteria,2NRZJ@2323|unclassified Bacteria	2|Bacteria	A	pathogenesis	CP_0034	-	-	ko:K02417,ko:K02519	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044,ko03012,ko03029	3.A.6.2,3.A.6.3	-	-	GPDPase_memb
SRD1_k127_2958209_3	1193181.BN10_1190004	0.0006761	51.0	2CT9V@1|root,32SSX@2|Bacteria,2GKR6@201174|Actinobacteria,4FH9P@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SRD1_k127_2958209_2	1450694.BTS2_0064	6.743e-08	64.0	28I6X@1|root,2Z89S@2|Bacteria,1TQMI@1239|Firmicutes,4HD5B@91061|Bacilli,1ZD3B@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF4350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
SRD1_k127_295974_1	64471.sync_2459	3.149e-87	294.0	COG0439@1|root,COG0439@2|Bacteria,1G1M0@1117|Cyanobacteria,1GYGC@1129|Synechococcus	1117|Cyanobacteria	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRD1_k127_295974_2	478741.JAFS01000001_gene1077	1.706e-14	79.0	COG0781@1|root,COG0781@2|Bacteria,46VCF@74201|Verrucomicrobia,37GZF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRD1_k127_295974_0	866776.HMPREF9321_1255	4.28e-144	486.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H360@909932|Negativicutes	909932|Negativicutes	M	Penicillin-binding Protein	pbpD	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRD1_k127_2963239_2	1121346.KB899824_gene3050	2.257e-29	122.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,4HIMM@91061|Bacilli,26SBK@186822|Paenibacillaceae	91061|Bacilli	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRD1_k127_2963239_0	748727.CLJU_c41770	2.034e-90	311.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,36DE7@31979|Clostridiaceae	186801|Clostridia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRD1_k127_2963239_1	1198452.Jab_1c09970	4.84e-53	195.0	arCOG07533@1|root,2ZF5I@2|Bacteria,1RB8D@1224|Proteobacteria,2W871@28216|Betaproteobacteria,477Z9@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRD1_k127_2963239_3	69042.WH5701_08294	5.083e-21	98.0	COG5642@1|root,COG5642@2|Bacteria,1GPRI@1117|Cyanobacteria,1H3QT@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
SRD1_k127_2963239_4	1123368.AUIS01000009_gene2436	9.158e-10	64.0	COG5654@1|root,COG5654@2|Bacteria,1N6P3@1224|Proteobacteria,1S7EU@1236|Gammaproteobacteria,2NE1H@225057|Acidithiobacillales	225057|Acidithiobacillales	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
SRD1_k127_2975664_0	1127134.NOCYR_3102	7.55e-150	483.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4FV1E@85025|Nocardiaceae	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRD1_k127_2975664_3	1394178.AWOO02000084_gene1175	0.0009251	51.0	2D9MJ@1|root,32SZC@2|Bacteria,2I8AM@201174|Actinobacteria,4EJ32@85012|Streptosporangiales	201174|Actinobacteria	C	Belongs to the cytochrome c oxidase bacterial subunit CtaF family	ctaF	-	-	-	-	-	-	-	-	-	-	-	Cyt_c_ox_IV
SRD1_k127_2975664_2	497964.CfE428DRAFT_5171	1.974e-58	205.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	fosB2	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRD1_k127_2975664_1	1123392.AQWL01000011_gene2252	1.162e-75	274.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,2VNEJ@28216|Betaproteobacteria,1KRY8@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
SRD1_k127_3012081_0	935866.JAER01000006_gene3314	0.0	1228.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4DMYN@85009|Propionibacteriales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRD1_k127_3012081_4	330214.NIDE3019	2.115e-41	167.0	COG0438@1|root,COG0438@2|Bacteria,3J19R@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD1_k127_3012081_7	1307759.JOMJ01000003_gene227	0.000812	51.0	COG0463@1|root,COG0463@2|Bacteria,1PAEK@1224|Proteobacteria,439Z1@68525|delta/epsilon subdivisions,2WZWX@28221|Deltaproteobacteria,2M7V9@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD1_k127_3012081_3	1200792.AKYF01000009_gene2953	4.517e-64	237.0	28K7U@1|root,2Z9VT@2|Bacteria,1VAFZ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3012081_1	484770.UFO1_4220	2.786e-142	471.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H20M@909932|Negativicutes	909932|Negativicutes	V	lipid A export permease ATP-binding protein MsbA	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
SRD1_k127_3012081_6	1094980.Mpsy_2388	1.127e-05	55.0	COG4818@1|root,arCOG04344@2157|Archaea,2XZ6C@28890|Euryarchaeota,2NBF8@224756|Methanomicrobia	224756|Methanomicrobia	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3012081_2	652103.Rpdx1_2249	2.722e-69	253.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2TSDP@28211|Alphaproteobacteria,3JSS4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	DNA photolyase	phrB	GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRD1_k127_3012081_5	1245475.ANAE01000192_gene3478	4.911e-08	59.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria,4EGUN@85012|Streptosporangiales	201174|Actinobacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
SRD1_k127_3026805_6	204669.Acid345_2356	2.601e-45	175.0	COG1466@1|root,COG1466@2|Bacteria,3Y2XE@57723|Acidobacteria,2JI6X@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRD1_k127_3026805_11	317619.ANKN01000207_gene2594	1.125e-07	64.0	COG0612@1|root,COG0612@2|Bacteria,1G2HZ@1117|Cyanobacteria,1MKJS@1212|Prochloraceae	1117|Cyanobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRD1_k127_3026805_0	401526.TcarDRAFT_0928	1.412e-224	714.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4H2PQ@909932|Negativicutes	909932|Negativicutes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRD1_k127_3026805_7	696281.Desru_1270	4.514e-44	173.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,261JF@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRD1_k127_3026805_8	1211115.ALIQ01000217_gene2412	8.747e-22	110.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2TRK1@28211|Alphaproteobacteria,3NACP@45404|Beijerinckiaceae	28211|Alphaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
SRD1_k127_3026805_5	1173025.GEI7407_1216	1.013e-47	175.0	COG0691@1|root,COG0691@2|Bacteria,1G542@1117|Cyanobacteria,1HAV9@1150|Oscillatoriales	1117|Cyanobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRD1_k127_3026805_9	1410618.JNKI01000003_gene2415	1.378e-20	106.0	COG2050@1|root,COG2050@2|Bacteria,1V824@1239|Firmicutes,4H4QB@909932|Negativicutes	909932|Negativicutes	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRD1_k127_3026805_12	706587.Desti_4025	5.508e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,2MRYH@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
SRD1_k127_3026805_4	1089553.Tph_c09580	1.081e-50	188.0	COG0639@1|root,COG0639@2|Bacteria,1UYWK@1239|Firmicutes,25DVG@186801|Clostridia,42IP1@68295|Thermoanaerobacterales	186801|Clostridia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRD1_k127_3026805_10	86106.I862_00660	3.225e-09	69.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
SRD1_k127_3026805_3	479435.Kfla_2120	7.126e-53	209.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,2GJC3@201174|Actinobacteria,4DNAW@85009|Propionibacteriales	201174|Actinobacteria	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
SRD1_k127_3026805_2	383372.Rcas_1860	1.15e-76	272.0	COG0303@1|root,COG0303@2|Bacteria,2G6F6@200795|Chloroflexi,376P1@32061|Chloroflexia	32061|Chloroflexia	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRD1_k127_3026805_1	941824.TCEL_00282	3.285e-105	351.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,36E42@31979|Clostridiaceae	186801|Clostridia	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRD1_k127_3054012_0	671143.DAMO_0319	3.598e-81	294.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2NP4I@2323|unclassified Bacteria	2|Bacteria	U	Metallo-beta-lactamase superfamily	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRD1_k127_3086720_3	1379270.AUXF01000002_gene1222	6.493e-19	96.0	COG2968@1|root,COG2968@2|Bacteria,1ZTTR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SRD1_k127_3086720_1	1121423.JONT01000013_gene345	1.367e-41	164.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,261I3@186807|Peptococcaceae	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SRD1_k127_3086720_0	1121428.DESHY_110149___1	8.684e-86	302.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,260Y3@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRD1_k127_3086720_2	1307759.JOMJ01000003_gene604	2.148e-19	98.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2WMJ5@28221|Deltaproteobacteria,2MA1F@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRD1_k127_310265_1	443144.GM21_1590	1.943e-12	74.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,43U0I@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
SRD1_k127_310639_2	469381.Dpep_0384	1.75e-49	194.0	COG0388@1|root,COG0388@2|Bacteria,3TC5X@508458|Synergistetes	508458|Synergistetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRD1_k127_310639_3	1463900.JOIX01000001_gene6231	2.275e-05	57.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
SRD1_k127_310639_1	1123504.JQKD01000012_gene1236	2.357e-79	280.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,2VJXC@28216|Betaproteobacteria,4ACYX@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRD1_k127_310639_0	661478.OP10G_2856	5.323e-201	661.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	swrC	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRD1_k127_3108741_2	1033734.CAET01000039_gene294	2.723e-19	101.0	COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,4HCYJ@91061|Bacilli,1ZAPI@1386|Bacillus	91061|Bacilli	S	membrane transporter protein	yxaA	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRD1_k127_3108741_0	1121378.KB899705_gene2546	4.022e-80	282.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,1WJ86@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	chorismate mutase domain of gram positive AroA protein	-	-	2.5.1.54,5.4.99.5	ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
SRD1_k127_3108741_3	1408304.JAHA01000003_gene3298	2.806e-11	73.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,4BZZB@830|Butyrivibrio	186801|Clostridia	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
SRD1_k127_3108741_1	682795.AciX8_4560	7.032e-69	242.0	COG2013@1|root,COG2013@2|Bacteria,3Y2XF@57723|Acidobacteria,2JIE5@204432|Acidobacteriia	204432|Acidobacteriia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
SRD1_k127_3123978_1	1170562.Cal6303_2806	1.788e-47	176.0	2CDHC@1|root,30QNS@2|Bacteria,1GBGU@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3123978_0	504728.K649_07615	4.696e-93	314.0	COG0624@1|root,COG0624@2|Bacteria,1WIRQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Peptidase family M20 M25 M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRD1_k127_3125264_3	1051632.TPY_3343	1.273e-07	59.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia	186801|Clostridia	K	response regulator receiver	-	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRD1_k127_3125264_2	521045.Kole_1586	1.625e-28	123.0	COG0705@1|root,COG0705@2|Bacteria,2GCZD@200918|Thermotogae	200918|Thermotogae	S	PFAM Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
SRD1_k127_3125264_1	439235.Dalk_4350	5.493e-92	316.0	COG1899@1|root,COG1899@2|Bacteria,1R3WQ@1224|Proteobacteria,42M57@68525|delta/epsilon subdivisions,2WJ6N@28221|Deltaproteobacteria,2MHW7@213118|Desulfobacterales	28221|Deltaproteobacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3125264_0	309801.trd_A0819	1.981e-101	343.0	COG0438@1|root,COG0438@2|Bacteria,2G683@200795|Chloroflexi,27XEV@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD1_k127_3125264_4	1292034.OR37_01260	1.82e-06	59.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2KFVI@204458|Caulobacterales	204458|Caulobacterales	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRD1_k127_3133226_0	649747.HMPREF0083_03564	1.819e-145	481.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,4HA8C@91061|Bacilli,26SWP@186822|Paenibacillaceae	91061|Bacilli	C	ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRD1_k127_3133226_1	292459.STH1316	3.202e-90	306.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,25CAJ@186801|Clostridia	186801|Clostridia	C	oxidoreductase beta subunit	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRD1_k127_3177411_11	693986.MOC_3625	8.86e-06	48.0	COG2801@1|root,COG2801@2|Bacteria,1PGP7@1224|Proteobacteria,2V97H@28211|Alphaproteobacteria,1JXU4@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3177411_4	1123288.SOV_4c04230	6.295e-82	293.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD1_k127_3177411_0	339670.Bamb_1597	2.25e-146	492.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9,Response_reg,dCache_1
SRD1_k127_3177411_3	1449126.JQKL01000053_gene3095	1.724e-89	300.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,249VX@186801|Clostridia,2687W@186813|unclassified Clostridiales	186801|Clostridia	K	Sigma-70 region 2	sigH	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
SRD1_k127_3177411_10	204669.Acid345_1003	9.306e-46	176.0	COG0566@1|root,COG0566@2|Bacteria,3Y3XM@57723|Acidobacteria,2JII0@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRD1_k127_3177411_2	338966.Ppro_0031	9.582e-119	400.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,43TS3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRD1_k127_3177411_6	477974.Daud_0187	2.803e-71	247.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,25ZYK@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM Serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
SRD1_k127_3177411_1	1121428.DESHY_150015___1	5.115e-143	472.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,26070@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRD1_k127_3177411_9	1321782.HMPREF1986_00037	2.032e-47	185.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,2PSCQ@265975|Oribacterium	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRD1_k127_3177411_8	1121423.JONT01000029_gene2391	4.095e-52	194.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,261YY@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
SRD1_k127_3177411_5	1511.CLOST_0163	1.466e-72	261.0	COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,248F4@186801|Clostridia,25QEQ@186804|Peptostreptococcaceae	186801|Clostridia	S	PIN domain protein	yacL	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_4,TRAM
SRD1_k127_3177411_7	635013.TherJR_2454	4.325e-70	250.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,260TE@186807|Peptococcaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRD1_k127_3178640_3	1043205.AFYF01000053_gene3122	4.79e-08	60.0	COG0277@1|root,COG0277@2|Bacteria,2H3K3@201174|Actinobacteria,4FGIM@85021|Intrasporangiaceae	201174|Actinobacteria	C	FAD binding domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
SRD1_k127_3178640_0	1382306.JNIM01000001_gene1617	2.713e-146	484.0	COG0277@1|root,COG0277@2|Bacteria,2G5TM@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD linked oxidase domain protein	-	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRD1_k127_3178640_4	765911.Thivi_3691	0.0003696	50.0	COG0642@1|root,COG1225@1|root,COG1225@2|Bacteria,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria,1WXM4@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRD1_k127_3178640_2	1185652.USDA257_c37940	1.245e-17	85.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,4B855@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Peroxiredoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRD1_k127_3178640_1	309801.trd_1708	3.669e-34	133.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi,27Y6P@189775|Thermomicrobia	189775|Thermomicrobia	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRD1_k127_3185482_0	246194.CHY_2107	4.616e-111	369.0	COG0475@1|root,COG0475@2|Bacteria,1UEAC@1239|Firmicutes,25J5R@186801|Clostridia,42FQK@68295|Thermoanaerobacterales	186801|Clostridia	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRD1_k127_3185482_1	1095769.CAHF01000023_gene587	4.703e-75	265.0	COG3391@1|root,COG3391@2|Bacteria,1MY07@1224|Proteobacteria,2VQUS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3185482_2	883126.HMPREF9710_04329	4.444e-35	155.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2WGNE@28216|Betaproteobacteria,472P2@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
SRD1_k127_3185482_3	622637.KE124774_gene3534	1.612e-30	135.0	2DBW8@1|root,2ZBF6@2|Bacteria,1NU24@1224|Proteobacteria,2UPMH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3189966_0	247490.KSU1_C0392	1.962e-276	873.0	COG0466@1|root,COG0466@2|Bacteria,2IYNA@203682|Planctomycetes	203682|Planctomycetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRD1_k127_3189966_1	518766.Rmar_1363	5.586e-96	333.0	COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD1_k127_326455_4	757424.Hsero_1277	4.058e-06	61.0	COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,2VJJ5@28216|Betaproteobacteria,472FD@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Outer membrane protein beta-barrel family	fecA	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	Plug,STN,TonB_dep_Rec
SRD1_k127_326455_1	1382306.JNIM01000001_gene2893	1.756e-82	288.0	COG4948@1|root,COG4948@2|Bacteria,2G8E6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Mandelate racemase muconate lactonizing protein	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRD1_k127_326455_0	266117.Rxyl_2779	1.055e-92	323.0	COG3367@1|root,COG3367@2|Bacteria,2IBUZ@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
SRD1_k127_326455_2	401526.TcarDRAFT_1875	2.728e-76	280.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD1_k127_326455_3	709986.Deima_0732	4.714e-18	93.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3335,Peptidase_C39_2
SRD1_k127_3292407_1	211165.AJLN01000116_gene3206	2.683e-12	71.0	COG0642@1|root,COG2205@2|Bacteria,1G45Q@1117|Cyanobacteria,1JHCE@1189|Stigonemataceae	1117|Cyanobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRD1_k127_3292407_0	1196323.ALKF01000173_gene46	1.195e-111	374.0	COG3538@1|root,COG3538@2|Bacteria,1TRJI@1239|Firmicutes,4HBQW@91061|Bacilli,26RH8@186822|Paenibacillaceae	91061|Bacilli	S	Glycosyl hydrolase	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
SRD1_k127_3329215_0	349161.Dred_0286	2.534e-166	533.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,2617C@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRD1_k127_3329215_9	1125712.HMPREF1316_1415	1.201e-54	208.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4CVQ4@84998|Coriobacteriia	84998|Coriobacteriia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRD1_k127_3329215_1	1379698.RBG1_1C00001G0516	1.719e-146	473.0	COG0473@1|root,COG0473@2|Bacteria,2NP1R@2323|unclassified Bacteria	2|Bacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRD1_k127_3329215_13	1172188.KB911824_gene3248	1.118e-37	147.0	COG0251@1|root,COG0251@2|Bacteria,2IIB2@201174|Actinobacteria,4FH2S@85021|Intrasporangiaceae	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRD1_k127_3329215_7	1007103.AFHW01000181_gene766	1.263e-70	249.0	COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,26TEW@186822|Paenibacillaceae	91061|Bacilli	L	DNA-3-methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRD1_k127_3329215_2	378806.STAUR_6551	3.886e-138	454.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WMIY@28221|Deltaproteobacteria,2YUCQ@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	bktB	-	2.3.1.16	ko:K07508	ko00062,ko00071,ko00280,ko01100,ko01110,ko01130,ko01212,map00062,map00071,map00280,map01100,map01110,map01130,map01212	M00085,M00087	R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
SRD1_k127_3329215_17	931277.C448_01439	2.462e-08	64.0	COG1714@1|root,arCOG03633@2157|Archaea,2Y0FR@28890|Euryarchaeota,23XUM@183963|Halobacteria	183963|Halobacteria	S	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRD1_k127_3329215_14	868131.MSWAN_1827	1.198e-35	140.0	COG4891@1|root,arCOG05264@2157|Archaea	2157|Archaea	S	Polyketide cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRD1_k127_3329215_15	383372.Rcas_3163	1.001e-16	82.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi,37631@32061|Chloroflexia	32061|Chloroflexia	I	PFAM Enoyl-CoA hydratase isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRD1_k127_3329215_10	1128421.JAGA01000003_gene2897	1.393e-52	190.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRD1_k127_3329215_5	316274.Haur_1203	3.806e-110	363.0	COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi	200795|Chloroflexi	C	3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRD1_k127_3329215_16	436229.JOEH01000026_gene2435	9.352e-14	83.0	COG2340@1|root,COG2340@2|Bacteria,2IPWK@201174|Actinobacteria,2NJ17@228398|Streptacidiphilus	201174|Actinobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRD1_k127_3329215_8	886293.Sinac_6412	3.387e-65	239.0	COG0520@1|root,COG0520@2|Bacteria,2IXCD@203682|Planctomycetes	203682|Planctomycetes	E	selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRD1_k127_3329215_12	1379698.RBG1_1C00001G0252	5.542e-43	163.0	COG2323@1|root,COG2323@2|Bacteria,2NR09@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
SRD1_k127_3329215_3	330214.NIDE3572	1.918e-128	428.0	28MGX@1|root,2ZATZ@2|Bacteria,3J0YU@40117|Nitrospirae	40117|Nitrospirae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3329215_6	1122182.KB903834_gene5745	1.61e-85	296.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DAC8@85008|Micromonosporales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	nodI	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
SRD1_k127_3329215_11	266117.Rxyl_1116	3.562e-48	194.0	COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria,4CPJK@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRD1_k127_3329215_4	1051632.TPY_0561	1.962e-113	380.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD1_k127_3358006_0	639030.JHVA01000001_gene3794	3.318e-05	58.0	COG1629@1|root,COG1629@2|Bacteria,3Y39P@57723|Acidobacteria,2JIP0@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRD1_k127_3374142_2	640511.BC1002_4975	1.206e-05	47.0	COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2VIAN@28216|Betaproteobacteria,1K1BS@119060|Burkholderiaceae	28216|Betaproteobacteria	I	acyl-CoA dehydrogenase	abmD	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_3374142_0	420324.KI912045_gene4378	3.886e-215	681.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TR3P@28211|Alphaproteobacteria,1JTXH@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	AMP-binding enzyme C-terminal domain	MA20_38120	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRD1_k127_3374142_1	76114.ebA2097	5.707e-09	57.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2VSJ7@28216|Betaproteobacteria,2KWS7@206389|Rhodocyclales	206389|Rhodocyclales	J	Endoribonuclease L-PSP	abmE	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRD1_k127_3464528_2	1227272.HMPREF1556_00833	9.788e-12	79.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,2FMJS@200643|Bacteroidia,22X9C@171551|Porphyromonadaceae	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRD1_k127_3464528_1	497964.CfE428DRAFT_6201	1.869e-31	136.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3464528_0	1117379.BABA_25296	3.655e-54	209.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,1V255@1239|Firmicutes,4HFUF@91061|Bacilli,1ZI0D@1386|Bacillus	91061|Bacilli	M	40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Cytochrom_D1,Lactonase,Phosphoesterase
SRD1_k127_3473788_1	215803.DB30_6305	0.0007209	48.0	COG3339@1|root,COG3339@2|Bacteria,1QT3B@1224|Proteobacteria,437QP@68525|delta/epsilon subdivisions,2X2Z7@28221|Deltaproteobacteria,2Z158@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRD1_k127_3473788_0	582899.Hden_2493	4.304e-08	55.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,3N8K5@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	Q	Flavin containing amine oxidoreductase	MA20_01895	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRD1_k127_3475563_2	479434.Sthe_1932	1.745e-34	140.0	COG0313@1|root,COG0313@2|Bacteria,2G6E3@200795|Chloroflexi,27Y2H@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRD1_k127_3475563_0	1894.JOER01000053_gene6134	1.391e-227	717.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRD1_k127_3475563_1	1033738.CAEP01000151_gene212	1.503e-57	214.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,26E0K@186818|Planococcaceae	91061|Bacilli	L	TatD related DNase	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRD1_k127_3480323_3	1303518.CCALI_02333	1.028e-66	250.0	COG1873@1|root,COG2239@1|root,COG1873@2|Bacteria,COG2239@2|Bacteria	2|Bacteria	P	Acts as a magnesium transporter	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,DUF2171,MgtE_N,PRC
SRD1_k127_3480323_1	909663.KI867150_gene247	6.724e-118	395.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2MQ96@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_3480323_4	269799.Gmet_0697	1.264e-65	233.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,43SF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRD1_k127_3480323_5	429009.Adeg_1796	6.73e-23	101.0	COG1254@1|root,COG1254@2|Bacteria,1UEN2@1239|Firmicutes,25JM5@186801|Clostridia,42HJX@68295|Thermoanaerobacterales	186801|Clostridia	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRD1_k127_3480323_0	47839.CCAU010000005_gene502	5.548e-203	646.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,23C9F@1762|Mycobacteriaceae	201174|Actinobacteria	C	Cyclic nucleotide-monophosphate binding domain	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
SRD1_k127_3480323_2	1184607.AUCHE_18_00040	2.908e-81	277.0	COG1297@1|root,COG1297@2|Bacteria,2I9UD@201174|Actinobacteria,4F7H1@85018|Dermatophilaceae	201174|Actinobacteria	S	OPT oligopeptide transporter protein	opt	-	-	-	-	-	-	-	-	-	-	-	OPT
SRD1_k127_3480714_1	525904.Tter_0675	2.297e-22	99.0	COG0294@1|root,COG0294@2|Bacteria,2NNN7@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,Pterin_bind
SRD1_k127_3480714_2	203119.Cthe_2582	9.672e-11	70.0	COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,24MN5@186801|Clostridia,3WKK7@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRD1_k127_3480714_0	1163408.UU9_15235	1.058e-29	135.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,1X6UH@135614|Xanthomonadales	135614|Xanthomonadales	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK2	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SRD1_k127_3497141_1	1121468.AUBR01000036_gene1302	2.27e-17	85.0	COG0664@1|root,COG0664@2|Bacteria,1V3XW@1239|Firmicutes,24HXX@186801|Clostridia,42GFA@68295|Thermoanaerobacterales	186801|Clostridia	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914,ko:K21563	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRD1_k127_3497141_0	264462.Bd0863	1.738e-43	173.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2MT2A@213481|Bdellovibrionales,2WJFJ@28221|Deltaproteobacteria	213481|Bdellovibrionales	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRD1_k127_3497141_2	1122236.KB905143_gene248	4.407e-05	55.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria,2KKNT@206350|Nitrosomonadales	206350|Nitrosomonadales	U	type II and III secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
SRD1_k127_3501856_11	1123508.JH636439_gene1485	4.568e-08	64.0	COG2812@1|root,COG2812@2|Bacteria,2J4XP@203682|Planctomycetes	203682|Planctomycetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
SRD1_k127_3501856_2	643648.Slip_0897	1.184e-118	386.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia,42JJA@68298|Syntrophomonadaceae	186801|Clostridia	F	Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage	-	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRD1_k127_3501856_6	32057.KB217478_gene2946	1.623e-39	153.0	COG1259@1|root,COG1259@2|Bacteria,1G4YX@1117|Cyanobacteria,1HJ2E@1161|Nostocales	1117|Cyanobacteria	S	PFAM Uncharacterised ACR, COG1259	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRD1_k127_3501856_8	1462527.CCDM010000001_gene1820	7.494e-21	109.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,23JWU@182709|Oceanobacillus	91061|Bacilli	M	Mechanosensitive ion channel	ykuT	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRD1_k127_3501856_1	713586.KB900536_gene1579	2.658e-122	402.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,1WWWF@135613|Chromatiales	135613|Chromatiales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRD1_k127_3501856_0	861299.J421_3227	4.726e-153	497.0	COG0334@1|root,COG0334@2|Bacteria,1ZSQB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRD1_k127_3501856_10	1448860.BBJO01000003_gene2652	1.457e-12	78.0	COG0695@1|root,arCOG02608@2157|Archaea,2XYXF@28890|Euryarchaeota,23WR6@183963|Halobacteria	183963|Halobacteria	O	COG0695 Glutaredoxin and related proteins	grx1	-	-	-	-	-	-	-	-	-	-	-	GST_N_3,Glutaredoxin
SRD1_k127_3501856_5	1196031.ALEG01000046_gene4509	1.03e-76	265.0	COG2043@1|root,COG2043@2|Bacteria,1TT5P@1239|Firmicutes,4HFED@91061|Bacilli,1ZAXA@1386|Bacillus	91061|Bacilli	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
SRD1_k127_3501856_12	1408419.JHYG01000006_gene2645	1.113e-06	59.0	COG0810@1|root,COG0810@2|Bacteria,1N8YY@1224|Proteobacteria	1224|Proteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRD1_k127_3501856_3	926692.AZYG01000013_gene913	1.819e-87	304.0	COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,248M5@186801|Clostridia,3WAK2@53433|Halanaerobiales	186801|Clostridia	C	TIGRFAM iron-sulfur cluster binding protein	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
SRD1_k127_3501856_4	204669.Acid345_3437	8.411e-82	281.0	COG2220@1|root,COG2220@2|Bacteria,3Y4RK@57723|Acidobacteria,2JM7M@204432|Acidobacteriia	204432|Acidobacteriia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRD1_k127_3501856_7	1382304.JNIL01000001_gene2859	4.216e-34	138.0	COG1392@1|root,COG1392@2|Bacteria	2|Bacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRD1_k127_3501856_9	443255.SCLAV_p0600	4.551e-13	72.0	COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria	201174|Actinobacteria	P	phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRD1_k127_3509455_2	1476583.DEIPH_ctg020orf0019	2.232e-38	156.0	COG0726@1|root,COG0726@2|Bacteria,1WIQX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRD1_k127_3509455_0	1499967.BAYZ01000028_gene1366	2.604e-130	434.0	COG3653@1|root,COG3653@2|Bacteria,2NNQ0@2323|unclassified Bacteria	2|Bacteria	Q	Amidohydrolase family	dan	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SRD1_k127_3509455_3	351160.RRC310	2.557e-18	87.0	COG3729@1|root,arCOG10926@2157|Archaea	2157|Archaea	S	general stress protein B in uncultured methanogenic archaeon (Q0W564)	-	-	-	-	-	-	-	-	-	-	-	-	LEA_5
SRD1_k127_3509455_1	760568.Desku_3301	3.464e-94	321.0	COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,25ZZA@186807|Peptococcaceae	186801|Clostridia	G	Sugar isomerase (SIS)	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
SRD1_k127_3524515_3	1382359.JIAL01000001_gene2312	4.59e-11	78.0	COG2911@1|root,COG2911@2|Bacteria,3Y3A6@57723|Acidobacteria,2JHS8@204432|Acidobacteriia	204432|Acidobacteriia	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
SRD1_k127_3524515_0	868595.Desca_1501	4.848e-77	273.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,248FR@186801|Clostridia,2612Z@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyltransferase family 28 C-terminal domain	ugtP	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
SRD1_k127_3524515_1	429009.Adeg_1435	3.651e-64	236.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,42G1M@68295|Thermoanaerobacterales	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRD1_k127_3524515_2	1122182.KB903825_gene285	3.558e-15	78.0	COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4DD5I@85008|Micromonosporales	201174|Actinobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRD1_k127_3531254_1	1267533.KB906734_gene4053	1.482e-61	220.0	2EFRH@1|root,339HI@2|Bacteria,3Y7RW@57723|Acidobacteria,2JN1K@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3531254_0	644966.Tmar_0974	3.167e-166	537.0	COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,2495P@186801|Clostridia,3WCQF@538999|Clostridiales incertae sedis	186801|Clostridia	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
SRD1_k127_3531254_3	1499968.TCA2_2289	3.767e-45	169.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HJTW@91061|Bacilli,26TMC@186822|Paenibacillaceae	91061|Bacilli	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def1	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRD1_k127_3531254_2	479434.Sthe_1176	6.605e-58	214.0	COG0223@1|root,COG0223@2|Bacteria,2G69J@200795|Chloroflexi,27XPA@189775|Thermomicrobia	189775|Thermomicrobia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRD1_k127_3531254_4	349520.PPE_02916	8.974e-30	125.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,26QFI@186822|Paenibacillaceae	91061|Bacilli	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
SRD1_k127_3537369_0	1120973.AQXL01000083_gene2912	2.467e-71	249.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli	91061|Bacilli	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	appB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRD1_k127_3537369_1	1123368.AUIS01000004_gene157	3.361e-64	241.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,2NE5V@225057|Acidithiobacillales	1236|Gammaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13889	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	SBP_bac_5
SRD1_k127_3537369_3	555079.Toce_1848	8.968e-05	50.0	COG1314@1|root,COG1314@2|Bacteria,1U4FP@1239|Firmicutes,24R3X@186801|Clostridia,42HEC@68295|Thermoanaerobacterales	186801|Clostridia	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRD1_k127_3537369_2	1122947.FR7_1836	3.535e-34	141.0	COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4H3ZP@909932|Negativicutes	909932|Negativicutes	S	Serine aminopeptidase, S33	est	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
SRD1_k127_3547126_1	1382306.JNIM01000001_gene2738	8.169e-132	431.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_3547126_4	1165841.SULAR_04617	3.2e-11	74.0	COG0789@1|root,COG0789@2|Bacteria,1N948@1224|Proteobacteria,42SGY@68525|delta/epsilon subdivisions,2YPH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	hspR	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRD1_k127_3547126_2	479434.Sthe_1709	4.23e-84	289.0	COG0484@1|root,COG0484@2|Bacteria,2G657@200795|Chloroflexi,27XSE@189775|Thermomicrobia	189775|Thermomicrobia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C
SRD1_k127_3547126_3	562970.Btus_1226	5.115e-28	123.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,278G9@186823|Alicyclobacillaceae	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRD1_k127_3547126_0	1209989.TepiRe1_1197	4.195e-255	801.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,42F10@68295|Thermoanaerobacterales	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRD1_k127_3633947_0	1303518.CCALI_02636	1.246e-61	225.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3633947_2	945713.IALB_2368	6.419e-37	149.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	yrrM	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
SRD1_k127_3633947_1	1303518.CCALI_01413	2.535e-54	200.0	COG0417@1|root,COG0417@2|Bacteria	2|Bacteria	L	DNA replication proofreading	polB	-	2.7.7.7	ko:K02336,ko:K06877,ko:K07501	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	CarbopepD_reg_2,DNA_pol_B,DNA_pol_B_exo1,DNA_pol_B_exo2,RNase_H_2
SRD1_k127_3636447_0	555079.Toce_1246	8.829e-180	574.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,42FHT@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRD1_k127_3636447_8	1380390.JIAT01000001_gene5040	5.724e-29	130.0	COG0726@1|root,COG0726@2|Bacteria,2H6C7@201174|Actinobacteria,4CRGB@84995|Rubrobacteria	84995|Rubrobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRD1_k127_3636447_2	1121422.AUMW01000003_gene938	1.347e-106	380.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,260B8@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the peptidase M16 family	ymxG	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRD1_k127_3636447_5	1121468.AUBR01000017_gene2368	4.406e-41	162.0	28NMK@1|root,2ZBN3@2|Bacteria,1TT4K@1239|Firmicutes,24EKK@186801|Clostridia,42FUC@68295|Thermoanaerobacterales	186801|Clostridia	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	amj	-	-	-	-	-	-	-	-	-	-	-	Amj
SRD1_k127_3636447_12	378806.STAUR_2716	0.0001645	51.0	COG0457@1|root,COG0457@2|Bacteria,1NEMW@1224|Proteobacteria,42WBX@68525|delta/epsilon subdivisions,2WRAD@28221|Deltaproteobacteria,2YXW6@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_8
SRD1_k127_3636447_4	1449063.JMLS01000007_gene3424	1.834e-49	196.0	COG1807@1|root,COG1807@2|Bacteria,1V10N@1239|Firmicutes,4I9MK@91061|Bacilli,271RA@186822|Paenibacillaceae	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRD1_k127_3636447_10	573061.Clocel_1541	4.354e-14	81.0	COG2246@1|root,COG2246@2|Bacteria,1VFGI@1239|Firmicutes,24RJP@186801|Clostridia	186801|Clostridia	S	PFAM GtrA family protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRD1_k127_3636447_3	926550.CLDAP_14070	1.212e-51	202.0	COG5542@1|root,COG5542@2|Bacteria,2G72S@200795|Chloroflexi	200795|Chloroflexi	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
SRD1_k127_3636447_11	268407.PWYN_01430	3.489e-13	81.0	COG0366@1|root,COG2819@1|root,COG4733@1|root,COG0366@2|Bacteria,COG2819@2|Bacteria,COG4733@2|Bacteria,1TSVI@1239|Firmicutes,4HCV2@91061|Bacilli,26R7N@186822|Paenibacillaceae	91061|Bacilli	G	belongs to the glycosyl hydrolase 13 family	nplT	GO:0005575,GO:0005576	3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54	ko:K01176,ko:K01208	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Alpha-amylase_N,CBM_20,CBM_25,Glyco_hydro_14,TIG,fn3
SRD1_k127_3636447_1	484770.UFO1_0462	3.336e-122	404.0	COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,4H22D@909932|Negativicutes	909932|Negativicutes	G	fructose-1,6-bisphosphatase	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRD1_k127_3636447_7	498761.HM1_0243	2.243e-32	133.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia	186801|Clostridia	F	HAD superfamily (Subfamily IIIA) phosphatase, TIGR01668	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
SRD1_k127_3636447_6	1121422.AUMW01000032_gene3073	1.347e-36	147.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,2619R@186807|Peptococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRD1_k127_3636447_9	926549.KI421517_gene1673	1.381e-17	92.0	COG1835@1|root,COG1835@2|Bacteria,4NXX0@976|Bacteroidetes	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRD1_k127_3654990_0	760568.Desku_2883	1.001e-26	114.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,2611Q@186807|Peptococcaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
SRD1_k127_3654990_1	1545701.LACWKB10_0940	2.217e-09	63.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,3F7D8@33958|Lactobacillaceae	91061|Bacilli	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRD1_k127_3679991_0	1121428.DESHY_50081___1	5.898e-107	360.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,2492A@186801|Clostridia,2608E@186807|Peptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRD1_k127_3679991_2	378806.STAUR_5048	7.02e-41	160.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,42RS9@68525|delta/epsilon subdivisions,2WP93@28221|Deltaproteobacteria,2Z1I1@29|Myxococcales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRD1_k127_3679991_1	469371.Tbis_0961	1.656e-95	333.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4DXZ6@85010|Pseudonocardiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRD1_k127_3679991_5	526226.Gbro_3565	9.89e-13	76.0	COG2197@1|root,COG2197@2|Bacteria,2GPKD@201174|Actinobacteria,4GBGV@85026|Gordoniaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRD1_k127_3679991_3	370438.PTH_1444	1.954e-40	157.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,266S4@186807|Peptococcaceae	186801|Clostridia	K	response regulator receiver	degU	-	-	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	M00478	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRD1_k127_3679991_4	1121335.Clst_1497	8.287e-27	118.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,3WHYU@541000|Ruminococcaceae	186801|Clostridia	K	PFAM response regulator receiver	degU	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD1_k127_370949_0	251221.35212555	6.012e-128	433.0	COG2366@1|root,COG2366@2|Bacteria,1G4M5@1117|Cyanobacteria	1117|Cyanobacteria	S	penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRD1_k127_370949_1	1122925.KB895379_gene2335	2.203e-08	57.0	COG0492@1|root,COG0492@2|Bacteria,1UXYT@1239|Firmicutes,4HDB8@91061|Bacilli,26TIG@186822|Paenibacillaceae	91061|Bacilli	O	pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRD1_k127_3714449_1	765952.PUV_10690	7.144e-71	252.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria	2|Bacteria	L	DNA ligase (ATP) activity	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRD1_k127_3714449_0	935866.JAER01000044_gene2851	1.825e-97	349.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4DT81@85009|Propionibacteriales	201174|Actinobacteria	L	DNA polymerase Ligase (LigD)	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRD1_k127_3714449_4	1172180.KB911777_gene1600	1.578e-05	52.0	COG1366@1|root,COG1366@2|Bacteria,2IMRK@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
SRD1_k127_3714449_2	649831.L083_6818	5.629e-19	95.0	COG0642@1|root,COG0745@1|root,COG2172@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2172@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria,4DCIN@85008|Micromonosporales	201174|Actinobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA,PAS_3,PAS_4,Response_reg,SpoIIE
SRD1_k127_372230_0	335283.Neut_1292	6.631e-177	562.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria,372V3@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRD1_k127_372230_1	1123368.AUIS01000009_gene2506	1.582e-29	123.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,2NC9C@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRD1_k127_3737209_2	861299.J421_6089	5.913e-41	170.0	COG1073@1|root,COG1680@1|root,COG1073@2|Bacteria,COG1680@2|Bacteria,1ZU86@142182|Gemmatimonadetes	2|Bacteria	V	Domain of unknown function (DUF3471)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Beta-lactamase,DUF3471,Hydrolase_4
SRD1_k127_3737209_4	278963.ATWD01000001_gene2590	9.268e-08	62.0	2C0SZ@1|root,32R7J@2|Bacteria,3Y4ZA@57723|Acidobacteria,2JJII@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3737209_1	1048339.KB913029_gene2475	1.608e-43	171.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4ES7T@85013|Frankiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRD1_k127_3737209_3	555088.DealDRAFT_2758	1.618e-25	110.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,24N57@186801|Clostridia,42KSU@68298|Syntrophomonadaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRD1_k127_3737209_0	1280676.AUJO01000001_gene2683	4.784e-78	274.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,4BX6V@830|Butyrivibrio	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
SRD1_k127_3737320_1	290397.Adeh_2455	1.176e-56	208.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRD1_k127_3737320_0	1048834.TC41_1648	1.955e-122	413.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli,2780N@186823|Alicyclobacillaceae	91061|Bacilli	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
SRD1_k127_3737320_2	1220589.CD32_02605	0.0006926	49.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,3IWIR@400634|Lysinibacillus	91061|Bacilli	KL	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRD1_k127_375443_2	1464048.JNZS01000030_gene1841	1.801e-29	123.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria,4DBSC@85008|Micromonosporales	201174|Actinobacteria	L	HhH-GPD superfamily base excision DNA repair protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRD1_k127_375443_1	1210884.HG799463_gene9368	2.041e-84	302.0	COG4805@1|root,COG4805@2|Bacteria,2IXQZ@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRD1_k127_375443_3	342113.DM82_4729	3.359e-06	57.0	28JQB@1|root,2Z9G8@2|Bacteria,1QCH9@1224|Proteobacteria,2VJJF@28216|Betaproteobacteria,1K17Y@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_375443_0	525904.Tter_0425	1.804e-119	391.0	COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria	2|Bacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRD1_k127_3766148_3	580340.Tlie_1233	1.573e-17	90.0	COG2020@1|root,COG2020@2|Bacteria,3TBA4@508458|Synergistetes	508458|Synergistetes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRD1_k127_3766148_1	357808.RoseRS_1853	1.836e-70	253.0	COG1089@1|root,COG1089@2|Bacteria,2G6AN@200795|Chloroflexi,3755V@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRD1_k127_3766148_0	479434.Sthe_2905	3.33e-157	501.0	COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi,27XFT@189775|Thermomicrobia	189775|Thermomicrobia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRD1_k127_3766148_2	1089550.ATTH01000001_gene136	8.555e-25	115.0	COG0697@1|root,COG0697@2|Bacteria,4PEK5@976|Bacteroidetes,1FJ8X@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRD1_k127_3783087_1	1157490.EL26_23180	1.087e-87	300.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,27857@186823|Alicyclobacillaceae	91061|Bacilli	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRD1_k127_3783087_2	431947.PGN_1131	7.269e-48	180.0	COG0321@1|root,COG1235@1|root,COG0321@2|Bacteria,COG1235@2|Bacteria,4NE14@976|Bacteroidetes,2FMSJ@200643|Bacteroidia,22XNX@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRD1_k127_3783087_0	751945.Theos_2092	5.88e-107	356.0	COG0320@1|root,COG0320@2|Bacteria,1WIE7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRD1_k127_3783087_3	1380394.JADL01000002_gene1077	1.549e-24	120.0	28J52@1|root,2Z90Y@2|Bacteria,1R3XK@1224|Proteobacteria,2U3J8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3783087_4	523850.TON_0902	7.138e-07	53.0	COG0340@1|root,arCOG01940@2157|Archaea,2XSZ5@28890|Euryarchaeota,243TN@183968|Thermococci	183968|Thermococci	H	Biotin protein ligase C terminal domain	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
SRD1_k127_379113_1	1121468.AUBR01000030_gene1228	6.783e-70	239.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,42ENW@68295|Thermoanaerobacterales	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRD1_k127_379113_0	635013.TherJR_1277	1.666e-160	511.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,260U5@186807|Peptococcaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRD1_k127_379113_4	1286171.EAL2_c15230	1.037e-10	68.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24J7X@186801|Clostridia	186801|Clostridia	S	Regulatory protein RecX	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRD1_k127_379113_3	483219.LILAB_22735	8.398e-31	132.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2WMQE@28221|Deltaproteobacteria,2YVJ7@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRD1_k127_379113_2	298655.KI912266_gene6312	3.087e-65	231.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4EUES@85013|Frankiales	201174|Actinobacteria	T	response regulator	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_379113_5	635013.TherJR_1349	2.983e-10	71.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,267CT@186807|Peptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07651	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9
SRD1_k127_3832186_0	1444309.JAQG01000157_gene3253	7.828e-33	138.0	COG3217@1|root,COG3217@2|Bacteria,1VGY3@1239|Firmicutes,4HPH2@91061|Bacilli,26UHF@186822|Paenibacillaceae	91061|Bacilli	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRD1_k127_3855433_4	204669.Acid345_1909	4.192e-24	116.0	COG2885@1|root,COG5295@1|root,COG2885@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	yeeJ	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Peptidase_S74,Phenol_MetA_deg,YadA_head,YadA_stalk
SRD1_k127_3855433_1	1192759.AKIB01000084_gene1289	7.402e-75	263.0	COG5654@1|root,COG5654@2|Bacteria,1PZ17@1224|Proteobacteria,2TVUN@28211|Alphaproteobacteria,2KE8E@204457|Sphingomonadales	204457|Sphingomonadales	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
SRD1_k127_3855433_2	631454.N177_1121	1.066e-45	168.0	COG5642@1|root,COG5642@2|Bacteria,1N1FN@1224|Proteobacteria,2VBHR@28211|Alphaproteobacteria,1JQKX@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
SRD1_k127_3855433_0	1121430.JMLG01000031_gene1635	1.081e-156	511.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,260SA@186807|Peptococcaceae	186801|Clostridia	O	PFAM magnesium chelatase	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRD1_k127_3855433_3	452637.Oter_0107	3.229e-28	127.0	COG2761@1|root,COG2761@2|Bacteria	2|Bacteria	Q	protein disulfide oxidoreductase activity	frnE	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRD1_k127_3855433_5	148814.JI66_03450	6.316e-05	52.0	COG4420@1|root,COG4420@2|Bacteria,1V46X@1239|Firmicutes,4HI49@91061|Bacilli,3F4FJ@33958|Lactobacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1003)	yejC	-	-	-	-	-	-	-	-	-	-	-	DUF1003
SRD1_k127_3900064_0	525904.Tter_2118	8.87e-110	368.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	hypBA2	-	-	-	-	-	-	-	-	-	-	-	BNR_2,Bac_rhamnosid6H,F5_F8_type_C,GDE_C,RicinB_lectin_2,Trehalase
SRD1_k127_3900064_1	338969.Rfer_0836	3.861e-25	112.0	COG2084@1|root,COG2084@2|Bacteria,1MXAD@1224|Proteobacteria,2W12X@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_2
SRD1_k127_3909510_11	211114.JOEF01000001_gene7312	3.487e-05	47.0	COG4447@1|root,COG4447@2|Bacteria,2I9D0@201174|Actinobacteria,4E6Z1@85010|Pseudonocardiales	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3909510_10	221288.JH992901_gene3593	3.906e-18	96.0	COG0457@1|root,COG2203@1|root,COG0457@2|Bacteria,COG2203@2|Bacteria,1GDWV@1117|Cyanobacteria	1117|Cyanobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF
SRD1_k127_3909510_8	395965.Msil_2998	7.91e-29	133.0	28J52@1|root,2Z90Y@2|Bacteria,1R3XK@1224|Proteobacteria,2U3J8@28211|Alphaproteobacteria,3NBXI@45404|Beijerinckiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3909510_9	1123377.AUIV01000022_gene1969	8.28e-21	102.0	COG1024@1|root,COG1024@2|Bacteria,1RAAV@1224|Proteobacteria,1RRTJ@1236|Gammaproteobacteria,1X44B@135614|Xanthomonadales	135614|Xanthomonadales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD1_k127_3909510_3	1273125.Rrhod_1685	3.485e-57	212.0	COG0697@1|root,COG0697@2|Bacteria,2GP9G@201174|Actinobacteria,4FYSV@85025|Nocardiaceae	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRD1_k127_3909510_2	713586.KB900536_gene2395	4.699e-120	392.0	COG0702@1|root,COG0702@2|Bacteria,1N12V@1224|Proteobacteria,1S93R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
SRD1_k127_3909510_5	314230.DSM3645_17575	3.305e-42	162.0	COG3476@1|root,COG3476@2|Bacteria,2J03F@203682|Planctomycetes	203682|Planctomycetes	T	PFAM TspO MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
SRD1_k127_3909510_1	1121920.AUAU01000012_gene2702	3.375e-149	488.0	COG0702@1|root,COG0702@2|Bacteria,3Y666@57723|Acidobacteria	57723|Acidobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
SRD1_k127_3909510_6	234267.Acid_5475	4.684e-40	163.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	ycgE	-	2.3.3.1	ko:K01647,ko:K18997,ko:K22491	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000,ko03000,ko03036	-	-	-	B12-binding,B12-binding_2,Citrate_synt,HTH_17,MerR_1
SRD1_k127_3909510_7	479432.Sros_0343	2.054e-32	133.0	2CGGQ@1|root,32S3Z@2|Bacteria,2IQ59@201174|Actinobacteria,4EKB1@85012|Streptosporangiales	201174|Actinobacteria	L	Protein of unknown function (DUF3140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3140
SRD1_k127_3909510_4	455632.SGR_3841	1.769e-53	209.0	COG1520@1|root,COG1520@2|Bacteria,2GW3X@201174|Actinobacteria	201174|Actinobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRD1_k127_3909510_0	1380394.JADL01000005_gene5669	4.216e-230	724.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria,2JWSX@204441|Rhodospirillales	204441|Rhodospirillales	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRD1_k127_3912795_1	1183438.GKIL_2012	1.045e-50	200.0	COG1807@1|root,COG1807@2|Bacteria,1G0YQ@1117|Cyanobacteria	1117|Cyanobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
SRD1_k127_3912795_0	1120973.AQXL01000116_gene281	4.061e-66	250.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,278YD@186823|Alicyclobacillaceae	91061|Bacilli	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRD1_k127_3912795_2	469383.Cwoe_5932	7.46e-50	184.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,4CPCJ@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRD1_k127_3943980_2	1128421.JAGA01000003_gene3248	2.549e-53	203.0	COG0477@1|root,COG2814@2|Bacteria,2NQ08@2323|unclassified Bacteria	2|Bacteria	EGP	MFS_1 like family	-	-	-	ko:K08151,ko:K08153	-	M00668,M00717	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75,2.A.1.2.8	-	-	MFS_1,MFS_1_like,Sugar_tr
SRD1_k127_3943980_0	1121377.KB906400_gene1327	2.322e-98	339.0	COG3538@1|root,COG3538@2|Bacteria	2|Bacteria	G	Metal-independent alpha-mannosidase (GH125)	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
SRD1_k127_3943980_1	234267.Acid_0123	2.672e-54	196.0	COG2096@1|root,COG2096@2|Bacteria,3Y77H@57723|Acidobacteria	57723|Acidobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRD1_k127_398392_4	497964.CfE428DRAFT_4964	5.974e-10	62.0	COG2165@1|root,COG2165@2|Bacteria,46T8M@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRD1_k127_398392_2	926550.CLDAP_05160	2.421e-11	76.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	2|Bacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRD1_k127_398392_3	526225.Gobs_4094	1.019e-10	75.0	COG5305@1|root,COG5305@2|Bacteria,2HTG8@201174|Actinobacteria,4ESH8@85013|Frankiales	201174|Actinobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRD1_k127_398392_1	742722.HMPREF9463_01497	1.279e-35	146.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4CUM2@84998|Coriobacteriia	84998|Coriobacteriia	K	RNA polymerase sigma-70 factor, sigma-B F G subfamily	-	-	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD1_k127_398392_0	338963.Pcar_2147	1.359e-53	193.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,43RZ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRD1_k127_3988032_4	880073.Calab_3087	1.198e-10	76.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SRD1_k127_3988032_3	1408254.T458_19885	2.288e-80	277.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,4HK2P@91061|Bacilli,276QJ@186822|Paenibacillaceae	91061|Bacilli	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRD1_k127_3988032_1	864702.OsccyDRAFT_1420	1.64e-232	739.0	COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria,1H7MX@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
SRD1_k127_3988032_0	251229.Chro_2176	0.0	1280.0	COG1452@1|root,COG1452@2|Bacteria,1G0TW@1117|Cyanobacteria,3VHNX@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Mannosyl oligosaccharide glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
SRD1_k127_3988032_2	1173024.KI912148_gene2853	9.998e-134	436.0	COG1249@1|root,COG1249@2|Bacteria,1G498@1117|Cyanobacteria	1117|Cyanobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRD1_k127_3992471_1	452637.Oter_0045	1.648e-74	259.0	COG1273@1|root,COG1273@2|Bacteria,46SB0@74201|Verrucomicrobia	74201|Verrucomicrobia	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRD1_k127_3992471_0	234267.Acid_6457	1.627e-110	374.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
SRD1_k127_3992471_2	1242864.D187_008324	2.616e-41	163.0	COG1295@1|root,COG1295@2|Bacteria,1R9UY@1224|Proteobacteria,42V9E@68525|delta/epsilon subdivisions,2WRIJ@28221|Deltaproteobacteria,2Z0W1@29|Myxococcales	28221|Deltaproteobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRD1_k127_3992471_3	204669.Acid345_0032	2.124e-17	83.0	2EIK5@1|root,33CBF@2|Bacteria,3Y5S5@57723|Acidobacteria,2JK2K@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_400473_1	1191523.MROS_1919	4.817e-22	104.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRD1_k127_400473_0	243231.GSU2043	2.39e-46	179.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRD1_k127_400473_4	309799.DICTH_0725	9.909e-11	70.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	Lectin_C,N_methyl,SBP_bac_10,T2SSG
SRD1_k127_400473_3	309799.DICTH_0725	8.304e-11	68.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	Lectin_C,N_methyl,SBP_bac_10,T2SSG
SRD1_k127_400473_2	1303518.CCALI_01546	6.526e-11	69.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
SRD1_k127_4009854_5	562970.Btus_1042	1.491e-18	97.0	COG2948@1|root,COG3103@1|root,COG2948@2|Bacteria,COG4991@2|Bacteria,1UM5I@1239|Firmicutes,4ITQI@91061|Bacilli,279SF@186823|Alicyclobacillaceae	91061|Bacilli	T	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
SRD1_k127_4009854_3	269800.Tfu_1507	6.095e-36	144.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,2IH0Y@201174|Actinobacteria,4EN4Q@85012|Streptosporangiales	201174|Actinobacteria	H	Metal binding domain of Ada	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1
SRD1_k127_4009854_1	1051632.TPY_3030	3.159e-112	376.0	COG0477@1|root,COG0477@2|Bacteria,1UIFU@1239|Firmicutes,25EMA@186801|Clostridia	186801|Clostridia	EGP	Sugar (and other) transporter	-	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1,MFS_4,Sugar_tr
SRD1_k127_4009854_0	1192034.CAP_5918	1.848e-203	644.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,2YY2T@29|Myxococcales	28221|Deltaproteobacteria	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SRD1_k127_4009854_2	370438.PTH_1146	3.543e-101	341.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,260SX@186807|Peptococcaceae	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRD1_k127_4009854_6	448385.sce0388	1.839e-18	99.0	COG0501@1|root,COG0501@2|Bacteria,1NG7Y@1224|Proteobacteria,439MR@68525|delta/epsilon subdivisions,2X4YW@28221|Deltaproteobacteria,2YZV7@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRD1_k127_4009854_4	326427.Cagg_3560	7.415e-24	109.0	COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi,374TR@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SRD1_k127_4017557_0	1209989.TepiRe1_0888	2.987e-307	965.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,42ETW@68295|Thermoanaerobacterales	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRD1_k127_4017557_2	313606.M23134_04004	5.855e-21	98.0	COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes,47PUS@768503|Cytophagia	976|Bacteroidetes	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD1_k127_4017557_4	797114.C475_10594	0.0001799	49.0	COG1917@1|root,arCOG03002@2157|Archaea,2XY21@28890|Euryarchaeota,23W3U@183963|Halobacteria	183963|Halobacteria	S	Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD1_k127_4017557_3	485913.Krac_6369	4.207e-12	72.0	COG0789@1|root,COG0789@2|Bacteria,2G7DC@200795|Chloroflexi	200795|Chloroflexi	K	Transcription regulator MerR DNA binding	-	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind
SRD1_k127_4017557_1	1123024.AUII01000028_gene2493	5.677e-69	238.0	COG0596@1|root,COG0596@2|Bacteria,2HEMJ@201174|Actinobacteria,4DYUK@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRD1_k127_4022991_8	926569.ANT_20600	9.113e-14	78.0	arCOG05710@1|root,33AIT@2|Bacteria,2G9CR@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4022991_2	1121428.DESHY_40238___1	4.036e-84	291.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,26001@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
SRD1_k127_4022991_0	479434.Sthe_2535	1.225e-112	376.0	COG1473@1|root,COG1473@2|Bacteria,2G5WT@200795|Chloroflexi,27XWM@189775|Thermomicrobia	200795|Chloroflexi	S	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRD1_k127_4022991_7	234267.Acid_7925	1.317e-17	90.0	COG3832@1|root,COG3832@2|Bacteria,3Y94H@57723|Acidobacteria	57723|Acidobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4022991_6	941449.dsx2_0178	1.165e-39	168.0	COG0431@1|root,COG0431@2|Bacteria,1RAFI@1224|Proteobacteria,42U4J@68525|delta/epsilon subdivisions,2WQ0R@28221|Deltaproteobacteria,2MGI5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
SRD1_k127_4022991_5	1121430.JMLG01000037_gene142	1.087e-61	221.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,260RP@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRD1_k127_4022991_1	66692.ABC2320	7.254e-95	333.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,1ZD3R@1386|Bacillus	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRD1_k127_4022991_3	1120936.KB907215_gene4230	2.592e-77	267.0	COG0414@1|root,COG0414@2|Bacteria,2GJEQ@201174|Actinobacteria,4EG66@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRD1_k127_4022991_4	1121472.AQWN01000004_gene781	3.901e-77	273.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,260CY@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRD1_k127_4022991_9	369723.Strop_0042	3.517e-07	57.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4DB9K@85008|Micromonosporales	201174|Actinobacteria	T	FHA domain	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
SRD1_k127_4026720_3	492774.JQMB01000010_gene4718	4.706e-06	51.0	COG0454@1|root,COG0456@2|Bacteria,1Q3NQ@1224|Proteobacteria,2VAD5@28211|Alphaproteobacteria,4BFVJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
SRD1_k127_4026720_0	1382306.JNIM01000001_gene2521	4.975e-184	586.0	COG1109@1|root,COG1109@2|Bacteria,2G5YP@200795|Chloroflexi	200795|Chloroflexi	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRD1_k127_4026720_1	471223.GWCH70_2217	5.44e-47	183.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,1WEN0@129337|Geobacillus	91061|Bacilli	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRD1_k127_4026720_2	1120973.AQXL01000132_gene2193	6.905e-31	127.0	COG4448@1|root,COG4448@2|Bacteria,1TRWI@1239|Firmicutes,4HAM1@91061|Bacilli,27A7C@186823|Alicyclobacillaceae	91061|Bacilli	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRD1_k127_4033061_0	1120971.AUCA01000001_gene1638	4.662e-237	744.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,278VH@186823|Alicyclobacillaceae	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD1_k127_4033061_1	1111479.AXAR01000005_gene605	2.546e-141	454.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4HBY4@91061|Bacilli	91061|Bacilli	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.82	ko:K09251	ko00330,ko01100,map00330,map01100	-	R01155	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_4043260_3	485913.Krac_1058	1.421e-22	101.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
SRD1_k127_4043260_7	1191523.MROS_0286	0.0001	52.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug
SRD1_k127_4043260_4	87626.PTD2_04958	6.016e-08	57.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4043260_0	1343158.SACS_1265	1.142e-156	505.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria,2JQAU@204441|Rhodospirillales	204441|Rhodospirillales	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRD1_k127_4043260_1	693661.Arcve_0456	3.262e-56	199.0	COG0105@1|root,arCOG04313@2157|Archaea,2XWSK@28890|Euryarchaeota,2465T@183980|Archaeoglobi	183980|Archaeoglobi	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRD1_k127_4043260_5	1385511.N783_17895	1.984e-07	63.0	COG4191@1|root,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,2Y8Y2@289201|Pontibacillus	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02491	ko02020,map02020	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,MEDS,PAS_8,PAS_9
SRD1_k127_4043260_6	269482.Bcep1808_1757	9.29e-05	55.0	COG0789@1|root,COG0789@2|Bacteria,1NMEN@1224|Proteobacteria,2W2FP@28216|Betaproteobacteria,1K800@119060|Burkholderiaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRD1_k127_4043260_2	335543.Sfum_3720	3.545e-30	128.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,2MQE0@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRD1_k127_4090521_2	266117.Rxyl_2693	5.258e-68	241.0	28IVI@1|root,2Z8TY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
SRD1_k127_4090521_3	1158050.KB895456_gene2025	6.788e-37	153.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	CCP_MauG,Copper-bind,Cu-oxidase_3,Cupredoxin_1
SRD1_k127_4090521_1	926554.KI912633_gene3916	1.346e-77	266.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRD1_k127_4090521_4	253839.SSNG_04458	1.237e-32	143.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF11
SRD1_k127_4090521_0	768671.ThimaDRAFT_0097	3.324e-137	475.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,SBP_bac_3
SRD1_k127_4090521_5	1123386.AUIW01000002_gene1257	3.27e-23	106.0	2E6PD@1|root,3319R@2|Bacteria,1WKCJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4108077_0	639030.JHVA01000001_gene3758	2.269e-111	370.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRD1_k127_4108077_4	656024.FsymDg_2257	4.419e-78	280.0	COG2132@1|root,COG2132@2|Bacteria,2HTNT@201174|Actinobacteria,4ETQF@85013|Frankiales	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRD1_k127_4108077_1	656024.FsymDg_2257	1.091e-105	354.0	COG2132@1|root,COG2132@2|Bacteria,2HTNT@201174|Actinobacteria,4ETQF@85013|Frankiales	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRD1_k127_4108077_3	639030.JHVA01000001_gene3758	1.309e-79	282.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRD1_k127_4108077_9	1120956.JHZK01000026_gene760	2.081e-05	56.0	COG4309@1|root,COG4309@2|Bacteria,1PTJ8@1224|Proteobacteria,2UMK5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
SRD1_k127_4108077_8	1317122.ATO12_07065	6.666e-06	57.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1HXJ2@117743|Flavobacteriia	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRD1_k127_4108077_5	767817.Desgi_0526	3.613e-57	218.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,263MV@186807|Peptococcaceae	186801|Clostridia	K	Transcriptional regulator with HTH domain and aminotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
SRD1_k127_4108077_7	889378.Spiaf_0083	6.502e-11	74.0	COG0705@1|root,COG0705@2|Bacteria,2J7HV@203691|Spirochaetes	203691|Spirochaetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRD1_k127_4108077_2	933262.AXAM01000028_gene3311	1.608e-92	316.0	COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,42MBD@68525|delta/epsilon subdivisions,2WJT1@28221|Deltaproteobacteria,2MI62@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM peptidase T-like protein	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRD1_k127_4108077_6	525904.Tter_0425	1.504e-38	147.0	COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria	2|Bacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRD1_k127_4111974_2	1329516.JPST01000036_gene2979	7.682e-27	112.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,27BBV@186824|Thermoactinomycetaceae	91061|Bacilli	F	Phosphorylase superfamily	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRD1_k127_4111974_3	742743.HMPREF9453_01379	4.361e-05	56.0	COG3307@1|root,COG3307@2|Bacteria,1TQGY@1239|Firmicutes,4H249@909932|Negativicutes	909932|Negativicutes	M	O-antigen polymerase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
SRD1_k127_4111974_0	70601.3256820	6.315e-74	259.0	COG1091@1|root,arCOG01367@2157|Archaea,2XVV7@28890|Euryarchaeota,243PG@183968|Thermococci	183968|Thermococci	M	RmlD substrate binding domain	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRD1_k127_4111974_1	1121272.KB903269_gene2	1.99e-54	204.0	COG0451@1|root,COG0451@2|Bacteria,2GNYX@201174|Actinobacteria,4D91F@85008|Micromonosporales	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRD1_k127_4134049_0	1122182.KB903813_gene2796	0.0008364	52.0	COG1216@1|root,COG1216@2|Bacteria,2ID7F@201174|Actinobacteria,4DC2P@85008|Micromonosporales	201174|Actinobacteria	S	Glycosyl transferase, family 2	-	-	-	ko:K16648	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	-
SRD1_k127_4148265_1	1278073.MYSTI_00134	5.477e-14	83.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.320	ko:K04786,ko:K13611,ko:K13612,ko:K13613,ko:K13614,ko:K16216	ko01053,map01053	-	-	-	ko00000,ko00001,ko01000,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,adh_short,ketoacyl-synt
SRD1_k127_4148265_0	370438.PTH_1049	7.744e-188	606.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,260AT@186807|Peptococcaceae	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRD1_k127_4148768_3	644283.Micau_2752	3.887e-54	196.0	COG2128@1|root,COG2128@2|Bacteria,2IG4S@201174|Actinobacteria,4DJKK@85008|Micromonosporales	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4148768_5	595536.ADVE02000001_gene1705	2.516e-41	169.0	COG3386@1|root,COG3386@2|Bacteria,1N3BV@1224|Proteobacteria	1224|Proteobacteria	G	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1
SRD1_k127_4148768_6	1131814.JAFO01000001_gene462	8.36e-23	104.0	2DXAI@1|root,3444M@2|Bacteria,1P0TN@1224|Proteobacteria,2UVMP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SRD1_k127_4148768_7	1035308.AQYY01000001_gene2353	4.623e-18	86.0	2FHD0@1|root,34978@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4148768_0	204669.Acid345_4167	2.175e-168	546.0	COG1520@1|root,COG1520@2|Bacteria,3Y2H2@57723|Acidobacteria,2JM3H@204432|Acidobacteriia	204432|Acidobacteriia	S	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	PQQ_3
SRD1_k127_4148768_2	1123256.KB907930_gene3484	6.56e-64	225.0	COG3917@1|root,COG3917@2|Bacteria,1RDNQ@1224|Proteobacteria,1S4HX@1236|Gammaproteobacteria,1XAEN@135614|Xanthomonadales	135614|Xanthomonadales	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRD1_k127_4148768_1	1449353.JQMQ01000005_gene5704	6.778e-78	265.0	COG2085@1|root,COG2085@2|Bacteria,2GMN3@201174|Actinobacteria,2NIXA@228398|Streptacidiphilus	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRD1_k127_4148768_4	497964.CfE428DRAFT_2098	4.17e-49	181.0	COG3791@1|root,COG3791@2|Bacteria,46T3T@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM glutathione-dependent formaldehyde-activating GFA	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRD1_k127_4154012_7	509191.AEDB02000035_gene2160	1.961e-12	81.0	COG0419@1|root,COG0419@2|Bacteria,1UI2P@1239|Firmicutes,25EBC@186801|Clostridia,3WK3Q@541000|Ruminococcaceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
SRD1_k127_4154012_3	935948.KE386494_gene979	1.896e-37	155.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia,42HKT@68295|Thermoanaerobacterales	186801|Clostridia	L	Calcineurin-like phosphoesterase	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
SRD1_k127_4154012_2	485916.Dtox_3344	1.217e-48	189.0	COG0530@1|root,COG0530@2|Bacteria,1UQT7@1239|Firmicutes,258JC@186801|Clostridia,260UA@186807|Peptococcaceae	186801|Clostridia	P	PFAM sodium calcium exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRD1_k127_4154012_6	756499.Desde_1452	7.331e-14	82.0	COG1266@1|root,COG1266@2|Bacteria,1V4WD@1239|Firmicutes,24P4C@186801|Clostridia,261SJ@186807|Peptococcaceae	186801|Clostridia	S	PFAM CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRD1_k127_4154012_1	420246.GTNG_0035	1.668e-51	197.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,1WF2Q@129337|Geobacillus	91061|Bacilli	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRD1_k127_4154012_5	401526.TcarDRAFT_1942	8.644e-32	135.0	COG3584@1|root,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,4H320@909932|Negativicutes	909932|Negativicutes	S	3D domain protein	-	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
SRD1_k127_4154012_0	867903.ThesuDRAFT_00051	3.366e-69	250.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,24ANI@186801|Clostridia,3WD9P@538999|Clostridiales incertae sedis	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD1_k127_4154012_4	1009370.ALO_14907	4.308e-35	145.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H34B@909932|Negativicutes	909932|Negativicutes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRD1_k127_4209137_1	272624.lpg0428	1.49e-09	66.0	COG0346@1|root,COG0346@2|Bacteria,1N6M5@1224|Proteobacteria,1SUW4@1236|Gammaproteobacteria,1JEWF@118969|Legionellales	118969|Legionellales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD1_k127_4209137_0	927677.ALVU02000004_gene4790	4.385e-59	227.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H57M@1142|Synechocystis	1117|Cyanobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS_3,PAS_9
SRD1_k127_4227617_2	485913.Krac_6502	3.651e-80	280.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,LTD,PKD,Pro-kuma_activ,fn3
SRD1_k127_4227617_3	1157640.AQWO01000031_gene2733	5.705e-26	116.0	COG2911@1|root,COG2911@2|Bacteria,2IFIC@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF642)	-	-	-	-	-	-	-	-	-	-	-	-	DUF642
SRD1_k127_4227617_5	1259795.ARJK01000003_gene1268	2.779e-15	85.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15,2.7.13.3	ko:K03564,ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AhpC-TSA
SRD1_k127_4227617_4	395963.Bind_2458	1.394e-19	105.0	28J52@1|root,2Z90Y@2|Bacteria,1R3XK@1224|Proteobacteria,2U3J8@28211|Alphaproteobacteria,3NBXI@45404|Beijerinckiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4227617_0	498211.CJA_3780	2.574e-114	391.0	28I5G@1|root,2Z88U@2|Bacteria,1R4MF@1224|Proteobacteria,1SK2A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4227617_1	498211.CJA_3779	3.984e-99	342.0	COG3258@1|root,COG3258@2|Bacteria,1R95B@1224|Proteobacteria,1RYPN@1236|Gammaproteobacteria,1FHKP@10|Cellvibrio	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4231283_5	1380390.JIAT01000011_gene2283	8.583e-06	56.0	COG0346@1|root,COG0346@2|Bacteria,2II8J@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD1_k127_4231283_1	861299.J421_1360	6.245e-136	454.0	COG2132@1|root,COG2132@2|Bacteria,1ZUD9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRD1_k127_4231283_2	1266908.AQPB01000031_gene1610	1.419e-49	183.0	COG0317@1|root,COG0317@2|Bacteria,1RKVU@1224|Proteobacteria,1SBBE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	Guanosine polyphosphate	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
SRD1_k127_4231283_4	204669.Acid345_1494	4.203e-09	66.0	COG0810@1|root,COG2203@1|root,COG0810@2|Bacteria,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,EAL,GAF,GAF_2,GGDEF,HATPase_c,HisKA,Hpt,Response_reg,TonB_C
SRD1_k127_4231283_0	234267.Acid_6173	1.095e-164	522.0	COG1741@1|root,COG1741@2|Bacteria,3Y367@57723|Acidobacteria	57723|Acidobacteria	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRD1_k127_4231283_3	1206744.BAGL01000064_gene4435	2.463e-25	115.0	29SM0@1|root,30DSB@2|Bacteria,2GN13@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4239)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
SRD1_k127_4231283_6	639030.JHVA01000001_gene3057	0.0001443	53.0	COG2755@1|root,COG3210@1|root,COG3386@1|root,COG3391@1|root,COG4932@1|root,COG2755@2|Bacteria,COG3210@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,3Y9DF@57723|Acidobacteria,2JMMK@204432|Acidobacteriia	204432|Acidobacteriia	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
SRD1_k127_4234235_2	1449338.JQLU01000004_gene133	5.166e-46	177.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,27FAV@186828|Carnobacteriaceae	91061|Bacilli	S	Dak1_2	yloV	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRD1_k127_4234235_0	1121472.AQWN01000002_gene2329	6.339e-91	310.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRD1_k127_4234235_1	552811.Dehly_1166	4.48e-50	194.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRD1_k127_4234235_3	1382356.JQMP01000003_gene1577	6.481e-13	76.0	COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi,27XYQ@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRD1_k127_4235580_17	266264.Rmet_2729	2.858e-23	106.0	COG1216@1|root,COG1216@2|Bacteria,1RFK0@1224|Proteobacteria,2VUIZ@28216|Betaproteobacteria,1JZUE@119060|Burkholderiaceae	28216|Betaproteobacteria	S	glycosyl transferase	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRD1_k127_4235580_10	266117.Rxyl_0503	1.278e-53	200.0	COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4CQC2@84995|Rubrobacteria	84995|Rubrobacteria	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRD1_k127_4235580_4	479434.Sthe_1821	4.092e-93	318.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi,27XRH@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
SRD1_k127_4235580_7	379066.GAU_0084	1.693e-66	242.0	28NUB@1|root,2ZBSR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4235580_8	1248916.ANFY01000010_gene419	4.693e-57	202.0	COG1917@1|root,COG1917@2|Bacteria,1RHHY@1224|Proteobacteria,2UCCW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_3
SRD1_k127_4235580_12	339670.Bamb_6339	5.247e-45	168.0	COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,2VT6E@28216|Betaproteobacteria,1K7PX@119060|Burkholderiaceae	28216|Betaproteobacteria	G	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD1_k127_4235580_13	1449976.KALB_2978	8.449e-44	163.0	COG3801@1|root,COG3801@2|Bacteria,2IR6E@201174|Actinobacteria,4E5K3@85010|Pseudonocardiales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRD1_k127_4235580_11	709797.CSIRO_3710	3.272e-47	172.0	COG0346@1|root,COG0346@2|Bacteria,1MZQY@1224|Proteobacteria,2UCNJ@28211|Alphaproteobacteria,3K0KX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD1_k127_4235580_6	871968.DESME_09380	1.046e-76	271.0	COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,249YC@186801|Clostridia	186801|Clostridia	S	Abc transporter	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRD1_k127_4235580_14	204669.Acid345_4513	3.976e-43	180.0	COG1668@1|root,COG1668@2|Bacteria,3Y2XV@57723|Acidobacteria,2JIQK@204432|Acidobacteriia	204432|Acidobacteriia	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRD1_k127_4235580_5	1123024.AUII01000026_gene2544	4.114e-92	312.0	COG1028@1|root,COG1028@2|Bacteria,2GMWG@201174|Actinobacteria,4E2QJ@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	fabG	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD1_k127_4235580_9	529818.AMSG_12444T0	4.454e-55	205.0	COG0183@1|root,COG1028@1|root,KOG1200@2759|Eukaryota,KOG1390@2759|Eukaryota	2759|Eukaryota	I	acetyl-CoA C-acetyltransferase activity	ACAT2	GO:0001101,GO:0001889,GO:0003674,GO:0003824,GO:0003985,GO:0003988,GO:0004312,GO:0004316,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005777,GO:0005829,GO:0006066,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0006694,GO:0006695,GO:0006720,GO:0007154,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007584,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008299,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009941,GO:0009987,GO:0009991,GO:0010033,GO:0016042,GO:0016054,GO:0016093,GO:0016094,GO:0016125,GO:0016126,GO:0016407,GO:0016408,GO:0016453,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0019348,GO:0019395,GO:0019408,GO:0019752,GO:0030258,GO:0030300,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032368,GO:0032370,GO:0032371,GO:0032373,GO:0032374,GO:0032376,GO:0032501,GO:0032502,GO:0032787,GO:0032879,GO:0033993,GO:0034440,GO:0042221,GO:0042579,GO:0042737,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0044057,GO:0044058,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045797,GO:0046165,GO:0046395,GO:0046872,GO:0046914,GO:0046950,GO:0046952,GO:0048513,GO:0048518,GO:0048731,GO:0048732,GO:0048856,GO:0050789,GO:0050896,GO:0051049,GO:0051050,GO:0051239,GO:0051240,GO:0051716,GO:0055114,GO:0060322,GO:0060456,GO:0061008,GO:0065007,GO:0070013,GO:0070542,GO:0070887,GO:0071229,GO:0071310,GO:0071396,GO:0071398,GO:0071496,GO:0071704,GO:0072329,GO:1901360,GO:1901362,GO:1901568,GO:1901569,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901700,GO:1901701,GO:1902224,GO:1902652,GO:1902653,GO:1904478,GO:1904480,GO:1904729,GO:1904731,GO:1905952,GO:1905954	1.1.1.100,2.3.1.9	ko:K00059,ko:K00626	ko00061,ko00071,ko00072,ko00280,ko00310,ko00333,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00780,ko00900,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00061,map00071,map00072,map00280,map00310,map00333,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00780,map00900,map01040,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00083,M00088,M00095,M00373,M00374,M00375,M00572	R00238,R01177,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00004,RC00029,RC00117,RC00326	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	-	-	iRC1080.CRv4_Au5_s3_g10590_t1	Thiolase_C,Thiolase_N,adh_short,adh_short_C2
SRD1_k127_4235580_2	1123024.AUII01000040_gene1336	2.501e-160	526.0	COG3243@1|root,COG3243@2|Bacteria,2GNYP@201174|Actinobacteria,4E13S@85010|Pseudonocardiales	201174|Actinobacteria	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	phbC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
SRD1_k127_4235580_16	1229203.KI301992_gene2156	1.711e-27	115.0	COG1396@1|root,COG1396@2|Bacteria,2IKVI@201174|Actinobacteria,3UXII@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRD1_k127_4235580_1	632518.Calow_1188	2.429e-167	539.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,42F4M@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRD1_k127_4235580_15	1449976.KALB_1440	2.823e-33	133.0	COG1522@1|root,COG1522@2|Bacteria,2IGNR@201174|Actinobacteria,4E5AB@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRD1_k127_4235580_0	643648.Slip_1625	0.0	1071.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,42JNI@68298|Syntrophomonadaceae	186801|Clostridia	H	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRD1_k127_4235580_3	1089553.Tph_c05830	8.983e-112	372.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia,42ES6@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRD1_k127_4262361_1	266117.Rxyl_2693	5.133e-57	215.0	28IVI@1|root,2Z8TY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
SRD1_k127_4262361_0	290397.Adeh_0544	2.144e-158	504.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42Z4J@68525|delta/epsilon subdivisions,2WUHY@28221|Deltaproteobacteria,2YWQR@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRD1_k127_4271538_2	1341151.ASZU01000010_gene1886	8.349e-38	151.0	COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,4HAV6@91061|Bacilli,27AW3@186824|Thermoactinomycetaceae	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRD1_k127_4271538_1	58344.JOEL01000022_gene988	5.994e-84	295.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF11
SRD1_k127_4271538_0	1121430.JMLG01000002_gene1080	1.727e-104	350.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,260DQ@186807|Peptococcaceae	186801|Clostridia	I	PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRD1_k127_4271538_3	1352941.M877_24420	0.0006797	48.0	COG2366@1|root,COG2366@2|Bacteria,2GISQ@201174|Actinobacteria	201174|Actinobacteria	J	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRD1_k127_4272462_0	67373.JOBF01000027_gene1528	3.021e-93	320.0	COG0119@1|root,COG0119@2|Bacteria	2|Bacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA2	-	2.3.1.182,2.3.3.13,2.3.3.14	ko:K01649,ko:K02594,ko:K09011	ko00290,ko00620,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00271,R01213,R07399	RC00004,RC00067,RC00470,RC01205,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRD1_k127_4272462_2	1283299.AUKG01000001_gene2504	1.323e-06	60.0	COG1708@1|root,COG1895@1|root,COG1708@2|Bacteria,COG1895@2|Bacteria,2IQ25@201174|Actinobacteria,4CQYA@84995|Rubrobacteria	84995|Rubrobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN,UPF0158
SRD1_k127_4272462_1	1128421.JAGA01000003_gene3178	6.265e-68	239.0	COG2362@1|root,COG2362@2|Bacteria,2NPDW@2323|unclassified Bacteria	2|Bacteria	E	D-aminopeptidase	dppA	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	iYO844.BSU12920	Peptidase_M55
SRD1_k127_4280501_0	1157490.EL26_00625	7.411e-182	588.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,2781B@186823|Alicyclobacillaceae	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRD1_k127_4280501_9	1185652.USDA257_c04120	1.627e-05	57.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4BA4K@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_2,TPR_8
SRD1_k127_4280501_10	1463841.JOIR01000015_gene6581	0.0005959	50.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria	201174|Actinobacteria	O	Cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRD1_k127_4280501_8	179408.Osc7112_5439	1.028e-12	79.0	COG0271@1|root,COG0271@2|Bacteria,1G7V3@1117|Cyanobacteria,1HCBA@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the BolA IbaG family	colA	-	-	-	-	-	-	-	-	-	-	-	BolA
SRD1_k127_4280501_5	330214.NIDE3582	1.719e-37	143.0	COG0278@1|root,COG0278@2|Bacteria	2|Bacteria	O	protein disulfide oxidoreductase activity	grxD	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	iPC815.YPO2383,iYL1228.KPN_01992	Glutaredoxin
SRD1_k127_4280501_7	2074.JNYD01000046_gene7295	1.471e-25	122.0	COG0642@1|root,COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,2GKN8@201174|Actinobacteria,4DZ1T@85010|Pseudonocardiales	201174|Actinobacteria	KT	Serine phosphatase RsbU, regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,SpoIIE
SRD1_k127_4280501_3	561175.KB894098_gene5452	1.103e-67	244.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,4EIDG@85012|Streptosporangiales	201174|Actinobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRD1_k127_4280501_2	867845.KI911784_gene544	5.279e-93	326.0	COG3552@1|root,COG3552@2|Bacteria,2G5IW@200795|Chloroflexi,3769V@32061|Chloroflexia	32061|Chloroflexia	S	SMART von Willebrand factor, type A	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRD1_k127_4280501_1	1313172.YM304_33360	2.886e-103	348.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4CMRT@84992|Acidimicrobiia	84992|Acidimicrobiia	O	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRD1_k127_4280501_4	479434.Sthe_3439	7.71e-65	231.0	COG1028@1|root,COG1028@2|Bacteria,2G8II@200795|Chloroflexi,27XKN@189775|Thermomicrobia	200795|Chloroflexi	IQ	Dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD1_k127_4280501_6	309801.trd_A0739	2.679e-27	119.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,27YHJ@189775|Thermomicrobia	189775|Thermomicrobia	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRD1_k127_4400452_1	926560.KE387023_gene2500	8.725e-38	151.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Malectin,TIG
SRD1_k127_4400452_0	694431.DESACE_04375	2.162e-66	242.0	COG3203@1|root,COG3203@2|Bacteria,1R19U@1224|Proteobacteria	1224|Proteobacteria	M	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
SRD1_k127_4408655_2	1295642.H839_01151	2.358e-82	286.0	COG1208@1|root,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,4HB6D@91061|Bacilli,1WG6H@129337|Geobacillus	91061|Bacilli	M	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I
SRD1_k127_4408655_0	1430331.EP10_03040	1.402e-192	625.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,1WEE2@129337|Geobacillus	91061|Bacilli	L	Exodeoxyribonuclease V, gamma subunit	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRD1_k127_4408655_3	1382305.AZUC01000047_gene811	6.59e-57	207.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli,26END@186818|Planococcaceae	91061|Bacilli	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22490	DapB_C,DapB_N
SRD1_k127_4408655_1	644966.Tmar_1034	2.956e-83	290.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,3WD07@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRD1_k127_4418974_4	1159488.SEQMU2_00770	1.749e-11	73.0	COG1011@1|root,COG1011@2|Bacteria,1TPBK@1239|Firmicutes,4HS7S@91061|Bacilli,4GYCV@90964|Staphylococcaceae	91061|Bacilli	S	Hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRD1_k127_4418974_3	1163409.UUA_09731	3.857e-46	179.0	2F845@1|root,31I6D@2|Bacteria,1QFVM@1224|Proteobacteria,1TD69@1236|Gammaproteobacteria,1XA7M@135614|Xanthomonadales	135614|Xanthomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4418974_2	1304284.L21TH_0442	1.465e-61	214.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,36IR5@31979|Clostridiaceae	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRD1_k127_4418974_1	273068.TTE2297	2.284e-68	235.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,42G2K@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRD1_k127_4418974_0	498761.HM1_1375	3.83e-145	467.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRD1_k127_4436025_20	1235457.C404_02065	1.026e-07	58.0	2E9SI@1|root,333YQ@2|Bacteria,1RI7T@1224|Proteobacteria,2VXBI@28216|Betaproteobacteria,1KHJN@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PsiF_repeat
SRD1_k127_4436025_1	1173029.JH980292_gene69	7.402e-103	368.0	COG5549@1|root,COG5549@2|Bacteria,1G2AK@1117|Cyanobacteria,1H6X4@1150|Oscillatoriales	1117|Cyanobacteria	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
SRD1_k127_4436025_11	518766.Rmar_0544	1.227e-47	182.0	COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,1FK1X@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SRD1_k127_4436025_8	1183438.GKIL_2935	1.676e-53	198.0	COG1680@1|root,COG1680@2|Bacteria,1G434@1117|Cyanobacteria	1117|Cyanobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRD1_k127_4436025_19	471857.Svir_34940	1.169e-08	64.0	COG2172@1|root,COG2203@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria,4DZ97@85010|Pseudonocardiales	201174|Actinobacteria	T	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,SpoIIE
SRD1_k127_4436025_21	882.DVU_1449	3.305e-06	60.0	COG1366@1|root,COG1366@2|Bacteria,1PAIK@1224|Proteobacteria,4327C@68525|delta/epsilon subdivisions,2WY6Y@28221|Deltaproteobacteria,2MCDJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRD1_k127_4436025_13	35754.JNYJ01000052_gene6631	4.147e-31	140.0	COG2208@1|root,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria,4D959@85008|Micromonosporales	201174|Actinobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,PAS_9,SpoIIE
SRD1_k127_4436025_2	1229205.BUPH_06577	1.078e-99	335.0	COG3391@1|root,COG3391@2|Bacteria,1R736@1224|Proteobacteria,2W0J3@28216|Betaproteobacteria,1K3JG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4436025_3	1121106.JQKB01000049_gene3064	3.15e-97	328.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TV61@28211|Alphaproteobacteria,2JVSA@204441|Rhodospirillales	204441|Rhodospirillales	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
SRD1_k127_4436025_17	402626.Rpic_3574	1.631e-24	114.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2VHPW@28216|Betaproteobacteria,1K55C@119060|Burkholderiaceae	28216|Betaproteobacteria	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRD1_k127_4436025_7	1040989.AWZU01000016_gene2485	7.684e-69	243.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2TRXF@28211|Alphaproteobacteria,3JSVF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRD1_k127_4436025_12	864051.BurJ1DRAFT_2739	3.567e-39	153.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VQ0S@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
SRD1_k127_4436025_5	404589.Anae109_1635	4.166e-74	263.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,42PR8@68525|delta/epsilon subdivisions,2WK8J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD1_k127_4436025_0	497964.CfE428DRAFT_0631	1.744e-172	574.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRD1_k127_4436025_18	379066.GAU_1341	2.002e-11	70.0	2E3MN@1|root,32NV6@2|Bacteria,1ZV65@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
SRD1_k127_4436025_4	323261.Noc_2970	1.719e-86	304.0	COG0843@1|root,COG0843@2|Bacteria,1QDZV@1224|Proteobacteria,1RYXY@1236|Gammaproteobacteria,1X0EJ@135613|Chromatiales	135613|Chromatiales	C	PFAM cytochrome c oxidase subunit I	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRD1_k127_4436025_15	671143.DAMO_0802	1.048e-26	117.0	COG1622@1|root,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cupredoxin_1
SRD1_k127_4436025_6	1380394.JADL01000005_gene5523	7.516e-72	250.0	COG2215@1|root,COG2215@2|Bacteria,1Q5ZJ@1224|Proteobacteria,2UQSQ@28211|Alphaproteobacteria,2JVV0@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4436025_9	1463856.JOHY01000009_gene6583	6.156e-50	189.0	COG1335@1|root,COG1335@2|Bacteria,2I9AW@201174|Actinobacteria	201174|Actinobacteria	Q	isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRD1_k127_4436025_10	1254432.SCE1572_07840	2.57e-48	186.0	COG1720@1|root,COG1720@2|Bacteria,1MYVG@1224|Proteobacteria,42N6M@68525|delta/epsilon subdivisions,2WPY9@28221|Deltaproteobacteria,2Z0U5@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0066	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II,UPF0066
SRD1_k127_4436025_14	2074.JNYD01000002_gene5675	1.376e-29	121.0	COG4274@1|root,COG4274@2|Bacteria,2IJ0R@201174|Actinobacteria,4ECGK@85010|Pseudonocardiales	201174|Actinobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRD1_k127_4464119_1	521674.Plim_1527	1.244e-48	180.0	COG1898@1|root,COG1898@2|Bacteria,2IZMV@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRD1_k127_4464119_0	693986.MOC_4202	2.058e-112	380.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TRNX@28211|Alphaproteobacteria,1JR4Z@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	PFAM amino acid permease-associated region	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
SRD1_k127_4468429_0	1123239.KB898623_gene1581	1.543e-72	261.0	COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,4HB9E@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
SRD1_k127_4468429_1	357808.RoseRS_3200	2.008e-22	99.0	COG0825@1|root,COG0825@2|Bacteria,2G7S3@200795|Chloroflexi,376V0@32061|Chloroflexia	32061|Chloroflexia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SRD1_k127_4469134_3	644966.Tmar_0397	8.439e-24	103.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	1.1.1.103,1.1.1.14	ko:K00008,ko:K00060	ko00040,ko00051,ko00260,ko01100,map00040,map00051,map00260,map01100	M00014	R00875,R01465,R01896	RC00085,RC00102,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD1_k127_4469134_0	1382306.JNIM01000001_gene2503	5.635e-81	285.0	COG1063@1|root,COG1063@2|Bacteria,2G8IZ@200795|Chloroflexi	200795|Chloroflexi	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD1_k127_4469134_2	604331.AUHY01000118_gene11	9.488e-32	128.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	Cupin_2,Cupin_7
SRD1_k127_4469134_1	1267535.KB906767_gene1609	2.642e-48	183.0	arCOG07533@1|root,2ZF5I@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRD1_k127_4488128_0	309799.DICTH_1642	5.104e-87	318.0	COG1609@1|root,COG2199@1|root,COG2203@1|root,COG2206@1|root,COG1609@2|Bacteria,COG2199@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	rpfG_3	-	-	ko:K02103,ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	GAF_2,GGDEF,HD,HD_5,HisKA_7TM,Peripla_BP_3
SRD1_k127_4488128_2	357808.RoseRS_3767	8.368e-10	65.0	COG1366@1|root,COG1366@2|Bacteria,2GAZW@200795|Chloroflexi,377MW@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS
SRD1_k127_4488128_1	237609.PSAKL28_30830	8.246e-36	151.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1S1K5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	alcohol dehydrogenase	tftE	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRD1_k127_4522512_1	1121472.AQWN01000005_gene2506	7.481e-74	276.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,2608Q@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRD1_k127_4522512_5	477974.Daud_0838	1.137e-23	110.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,24M2Q@186801|Clostridia,261QR@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SRD1_k127_4522512_2	1111479.AXAR01000016_gene3092	5.427e-51	185.0	COG1666@1|root,COG1666@2|Bacteria,1V3UR@1239|Firmicutes,4HHVD@91061|Bacilli,278D5@186823|Alicyclobacillaceae	91061|Bacilli	S	Belongs to the UPF0234 family	yitK	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
SRD1_k127_4522512_0	1051632.TPY_1661	8.323e-110	372.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,3WCEW@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
SRD1_k127_4522512_3	555079.Toce_0770	1.589e-45	182.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,24AAY@186801|Clostridia,42F9G@68295|Thermoanaerobacterales	186801|Clostridia	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	lytR	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRD1_k127_4522512_4	273068.TTE0866	1.635e-35	149.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,249SN@186801|Clostridia,42FIW@68295|Thermoanaerobacterales	186801|Clostridia	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,ChW,Polysacc_deac_1
SRD1_k127_454928_4	996637.SGM_0043	6.735e-06	53.0	COG1366@1|root,COG1366@2|Bacteria,2GUNY@201174|Actinobacteria	201174|Actinobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS_2
SRD1_k127_454928_2	1283287.KB822580_gene1633	7.865e-38	149.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4DPF2@85009|Propionibacteriales	201174|Actinobacteria	K	RNA polymerase sigma	sigF	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD1_k127_454928_3	68223.JNZY01000005_gene4081	3.473e-26	118.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria	201174|Actinobacteria	T	protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,PAS_4,SpoIIE,sCache_3_2
SRD1_k127_454928_0	1463887.KL590067_gene6225	5.743e-121	402.0	COG3391@1|root,COG3391@2|Bacteria,2GP3N@201174|Actinobacteria	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_454928_1	861299.J421_0365	3.204e-62	225.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRD1_k127_4555923_5	1382306.JNIM01000001_gene963	9.939e-13	70.0	COG0193@1|root,COG1082@1|root,COG0193@2|Bacteria,COG1082@2|Bacteria,2G6SW@200795|Chloroflexi	200795|Chloroflexi	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRD1_k127_4555923_6	639030.JHVA01000001_gene3318	4.231e-12	69.0	29WS1@1|root,30ID4@2|Bacteria,3Y5IE@57723|Acidobacteria,2JK0W@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
SRD1_k127_4555923_4	591001.Acfer_0595	2.338e-15	85.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,4H30H@909932|Negativicutes	909932|Negativicutes	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRD1_k127_4555923_0	247490.KSU1_C0426	5.227e-58	214.0	COG1131@1|root,COG1131@2|Bacteria,2IZYW@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,DUF4162
SRD1_k127_4555923_3	985053.VMUT_0331	8.192e-16	88.0	COG0842@1|root,arCOG01465@2157|Archaea,2XQB0@28889|Crenarchaeota	28889|Crenarchaeota	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRD1_k127_4555923_1	1231241.Mc24_00460	9.195e-46	174.0	COG0461@1|root,COG0461@2|Bacteria,2GD2M@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRD1_k127_4555923_2	1232683.ADIMK_0381	2.003e-29	121.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,464PB@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750	OMPdecase
SRD1_k127_4575832_7	640081.Dsui_1785	0.0003356	53.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2VHVG@28216|Betaproteobacteria,2KX8G@206389|Rhodocyclales	206389|Rhodocyclales	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_8
SRD1_k127_4575832_4	536227.CcarbDRAFT_3578	3.623e-37	151.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,36I3Z@31979|Clostridiaceae	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRD1_k127_4575832_0	204669.Acid345_3065	2.53e-184	598.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
SRD1_k127_4575832_5	762903.Pedsa_1793	2.607e-20	105.0	28J8U@1|root,33EE0@2|Bacteria	2|Bacteria	S	Hypothetical glycosyl hydrolase family 15	-	-	-	-	-	-	-	-	-	-	-	-	GHL15
SRD1_k127_4575832_1	1122925.KB895380_gene4098	2.835e-86	299.0	COG3538@1|root,COG3538@2|Bacteria,1TRJI@1239|Firmicutes,4HBQW@91061|Bacilli,26RH8@186822|Paenibacillaceae	91061|Bacilli	S	Glycosyl hydrolase	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
SRD1_k127_4575832_2	469382.Hbor_09240	6.668e-71	253.0	COG3608@1|root,arCOG02890@2157|Archaea,2XUVB@28890|Euryarchaeota,23UWM@183963|Halobacteria	183963|Halobacteria	S	Deacylase	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
SRD1_k127_4575832_6	1320556.AVBP01000001_gene4481	4.795e-09	66.0	COG3153@1|root,COG3153@2|Bacteria,1QU4W@1224|Proteobacteria,2TVZP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD1_k127_4575832_3	1303518.CCALI_00438	3.35e-64	241.0	COG2027@1|root,COG2027@2|Bacteria	2|Bacteria	M	serine-type D-Ala-D-Ala carboxypeptidase activity	dacB	GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006508,GO:0006807,GO:0007049,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009987,GO:0016043,GO:0016787,GO:0016998,GO:0017171,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0032505,GO:0033218,GO:0033293,GO:0036094,GO:0042597,GO:0043093,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044464,GO:0045229,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0097159,GO:0140096,GO:1901135,GO:1901136,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901681	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	iAPECO1_1312.APECO1_3250,iECOK1_1307.ECOK1_3603,iECS88_1305.ECS88_3564,iUMN146_1321.UM146_00470,iUTI89_1310.UTI89_C3615,iYL1228.KPN_03592	DUF1460,Peptidase_S13
SRD1_k127_4587562_2	562970.Btus_3150	5.968e-45	181.0	COG4632@1|root,COG4632@2|Bacteria,1TQBV@1239|Firmicutes,4I2CK@91061|Bacilli,278I6@186823|Alicyclobacillaceae	91061|Bacilli	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA,SLH
SRD1_k127_4587562_3	1172188.KB911821_gene1259	2.497e-16	89.0	COG2367@1|root,COG2367@2|Bacteria,2IC8Y@201174|Actinobacteria,4FFT7@85021|Intrasporangiaceae	201174|Actinobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRD1_k127_4587562_4	288705.RSal33209_2432	8.636e-07	54.0	2CDGH@1|root,348SI@2|Bacteria,2GZQG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4587562_0	1396.DJ87_3433	1.269e-231	765.0	COG0567@1|root,COG0567@2|Bacteria,1TRDW@1239|Firmicutes,4HAUI@91061|Bacilli,1ZAX3@1386|Bacillus	91061|Bacilli	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)	odhA	GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRD1_k127_4587562_1	316274.Haur_4513	7.9e-100	347.0	COG1249@1|root,COG1249@2|Bacteria,2G5MR@200795|Chloroflexi,374XR@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRD1_k127_4601387_0	909663.KI867150_gene214	9.065e-79	278.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
SRD1_k127_4601387_1	234267.Acid_0104	3.675e-56	207.0	COG0457@1|root,COG0457@2|Bacteria,3Y3RA@57723|Acidobacteria	57723|Acidobacteria	M	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
SRD1_k127_464883_1	1242864.D187_009579	5.69e-08	65.0	COG4099@1|root,COG4099@2|Bacteria,1R99N@1224|Proteobacteria	1224|Proteobacteria	S	phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd,Peptidase_S9
SRD1_k127_464883_0	765420.OSCT_1185	1.95e-81	278.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2G64C@200795|Chloroflexi,376K3@32061|Chloroflexia	32061|Chloroflexia	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SRD1_k127_4661672_0	635013.TherJR_1770	9.267e-102	342.0	COG1060@1|root,COG1060@2|Bacteria,1TRHG@1239|Firmicutes,247Z2@186801|Clostridia,2609W@186807|Peptococcaceae	186801|Clostridia	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1,2.5.1.77	ko:K11779,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRD1_k127_4661672_1	44251.PDUR_17480	1.563e-49	189.0	COG1427@1|root,COG1427@2|Bacteria,1V2PX@1239|Firmicutes,4HFX0@91061|Bacilli,26T7N@186822|Paenibacillaceae	91061|Bacilli	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRD1_k127_4661672_2	292459.STH817	1.72e-09	60.0	COG1060@1|root,COG1060@2|Bacteria,1TQNG@1239|Firmicutes,24AHE@186801|Clostridia	186801|Clostridia	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SRD1_k127_4668473_2	682795.AciX8_4071	3.181e-12	67.0	COG4977@1|root,COG4977@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	glxA	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRD1_k127_4668473_1	204669.Acid345_4011	3.238e-22	101.0	2ED19@1|root,336Y7@2|Bacteria,3Y95N@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4668473_0	1403819.BATR01000022_gene806	9.513e-157	529.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRD1_k127_4672345_0	748247.AZKH_1490	6.572e-60	215.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,2VMMF@28216|Betaproteobacteria,2KXTY@206389|Rhodocyclales	206389|Rhodocyclales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1343
SRD1_k127_4672345_1	1123311.KB904462_gene1114	1.95e-57	208.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4HEGD@91061|Bacilli	91061|Bacilli	T	Transcriptional regulator	mprA1	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_4672345_2	936572.HMPREF1148_2057	1.849e-33	144.0	COG5002@1|root,COG5002@2|Bacteria,1TS83@1239|Firmicutes,4H1V5@909932|Negativicutes	909932|Negativicutes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRD1_k127_4704643_3	744872.Spica_1525	1.742e-07	59.0	COG1298@1|root,COG1298@2|Bacteria,2J57F@203691|Spirochaetes	203691|Spirochaetes	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
SRD1_k127_4704643_0	246194.CHY_1512	2.682e-86	303.0	COG0342@1|root,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,42F9I@68295|Thermoanaerobacterales	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRD1_k127_4704643_2	935948.KE386495_gene2099	1.922e-56	212.0	COG0341@1|root,COG0341@2|Bacteria,1TSZE@1239|Firmicutes,249A3@186801|Clostridia,42EUX@68295|Thermoanaerobacterales	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRD1_k127_4704643_1	246194.CHY_0502	2.177e-62	226.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,42EQ0@68295|Thermoanaerobacterales	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,Nitro_FeMo-Co,ZT_dimer
SRD1_k127_4712874_8	158190.SpiGrapes_3082	5.139e-13	73.0	2AHWM@1|root,3189H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4712874_6	1114972.AUAW01000007_gene2611	2.895e-18	91.0	COG1670@1|root,COG1670@2|Bacteria,1VC3X@1239|Firmicutes,4HKVZ@91061|Bacilli,3F5IW@33958|Lactobacillaceae	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,Acetyltransf_4
SRD1_k127_4712874_10	1117108.PAALTS15_01222	0.0002211	51.0	COG1670@1|root,COG1670@2|Bacteria,1V5TN@1239|Firmicutes,4HIF4@91061|Bacilli,26WN8@186822|Paenibacillaceae	91061|Bacilli	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRD1_k127_4712874_9	929713.NIASO_00255	1.581e-06	61.0	COG3577@1|root,COG3577@2|Bacteria,4NMGA@976|Bacteroidetes,1ITQS@117747|Sphingobacteriia	976|Bacteroidetes	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
SRD1_k127_4712874_7	215803.DB30_0544	2.643e-17	93.0	COG4395@1|root,COG4395@2|Bacteria,1NKJZ@1224|Proteobacteria,43793@68525|delta/epsilon subdivisions,2X2CB@28221|Deltaproteobacteria,2YYKJ@29|Myxococcales	28221|Deltaproteobacteria	S	Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
SRD1_k127_4712874_1	368407.Memar_0638	5.193e-50	191.0	COG0648@1|root,arCOG01894@2157|Archaea,2XV5I@28890|Euryarchaeota	28890|Euryarchaeota	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRD1_k127_4712874_3	867903.ThesuDRAFT_00114	3.915e-38	154.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia,3WCK5@538999|Clostridiales incertae sedis	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRD1_k127_4712874_4	702450.CUW_1879	6.923e-30	128.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,3VQ6Q@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRD1_k127_4712874_2	1007103.AFHW01000082_gene1522	4.671e-44	175.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,4HBPI@91061|Bacilli,26STU@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRD1_k127_4712874_5	640132.Srot_0008	4.278e-28	122.0	COG0494@1|root,COG0494@2|Bacteria,2GWEB@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the NUDIX hydrolase family	mutT4	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRD1_k127_4712874_0	243274.THEMA_03655	9.938e-51	185.0	COG1003@1|root,COG1003@2|Bacteria,2GCBU@200918|Thermotogae	200918|Thermotogae	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRD1_k127_4774580_0	234267.Acid_5837	0.0	1138.0	COG1201@1|root,COG1201@2|Bacteria,3Y348@57723|Acidobacteria	57723|Acidobacteria	L	DEAD DEAH box	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRD1_k127_4774580_16	1278073.MYSTI_00185	4.923e-15	89.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,438BA@68525|delta/epsilon subdivisions,2X3KK@28221|Deltaproteobacteria,2YWFN@29|Myxococcales	28221|Deltaproteobacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRD1_k127_4774580_9	653045.Strvi_2780	2.172e-39	157.0	COG1418@1|root,COG1418@2|Bacteria,2GJPC@201174|Actinobacteria	201174|Actinobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRD1_k127_4774580_11	1005048.CFU_4272	3.132e-30	128.0	COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria	1224|Proteobacteria	E	Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRD1_k127_4774580_7	253839.SSNG_04458	1.991e-43	175.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF11
SRD1_k127_4774580_15	58344.JOEL01000022_gene988	1.652e-20	107.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF11
SRD1_k127_4774580_8	743721.Psesu_1933	2.853e-40	160.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,1X6DF@135614|Xanthomonadales	135614|Xanthomonadales	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
SRD1_k127_4774580_4	404589.Anae109_1540	7.805e-50	188.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRD1_k127_4774580_12	1341181.FLJC2902T_23580	2.006e-28	123.0	COG2764@1|root,COG2764@2|Bacteria,4NQD7@976|Bacteroidetes,1I2AQ@117743|Flavobacteriia,2NW94@237|Flavobacterium	976|Bacteroidetes	S	Glyoxalase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
SRD1_k127_4774580_10	1121272.KB903249_gene2086	5.825e-34	134.0	2B1D5@1|root,31TTS@2|Bacteria,2GSZW@201174|Actinobacteria,4DJGA@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4774580_1	323261.Noc_0471	2.168e-259	814.0	COG0028@1|root,COG0028@2|Bacteria,1MWKP@1224|Proteobacteria,1RNYT@1236|Gammaproteobacteria,1X0MF@135613|Chromatiales	135613|Chromatiales	EH	Thiamine pyrophosphate enzyme, central domain	-	-	1.2.5.1	ko:K00156	ko00620,map00620	-	R03145	RC00860	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRD1_k127_4774580_13	1173028.ANKO01000089_gene3628	8.812e-28	119.0	COG1845@1|root,COG1845@2|Bacteria,1G02A@1117|Cyanobacteria,1H849@1150|Oscillatoriales	1117|Cyanobacteria	C	Heme copper-type cytochrome quinol oxidase subunit 3	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRD1_k127_4774580_3	525909.Afer_1826	1.885e-53	207.0	COG0723@1|root,COG0723@2|Bacteria,2GIX6@201174|Actinobacteria,4CNF9@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03890	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Rieske
SRD1_k127_4774580_2	35754.JNYJ01000075_gene8654	5.94e-148	488.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4DAJX@85008|Micromonosporales	201174|Actinobacteria	C	Cytochrome b	qcrB	-	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
SRD1_k127_4774580_14	640512.BC1003_4038	4.73e-26	117.0	COG3336@1|root,COG3336@2|Bacteria,1RDWT@1224|Proteobacteria,2VRQE@28216|Betaproteobacteria,1K234@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Cytochrome c oxidase caa3-type, assembly factor	-	-	-	ko:K02351	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
SRD1_k127_4774580_6	365528.KB891203_gene3440	8.344e-44	168.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria,4ESET@85013|Frankiales	201174|Actinobacteria	C	cytochrome C	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
SRD1_k127_4774580_5	365528.KB891203_gene3450	4.835e-47	179.0	COG1622@1|root,COG1622@2|Bacteria,2GNXA@201174|Actinobacteria,4ESMU@85013|Frankiales	201174|Actinobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRD1_k127_4797555_3	1380763.BG53_11590	1.869e-80	274.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,26R4N@186822|Paenibacillaceae	91061|Bacilli	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRD1_k127_4797555_7	944479.JQLX01000011_gene866	1.992e-07	60.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2X64M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Molydopterin dinucleotide binding domain	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdopterin,Molydop_binding
SRD1_k127_4797555_4	694431.DESACE_04375	4.459e-61	226.0	COG3203@1|root,COG3203@2|Bacteria,1R19U@1224|Proteobacteria	1224|Proteobacteria	M	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
SRD1_k127_4797555_5	1449346.JQMO01000001_gene7043	2.86e-55	209.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF11
SRD1_k127_4797555_0	867845.KI911784_gene881	4.582e-140	452.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,3754I@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRD1_k127_4797555_1	632518.Calow_1631	2.808e-128	419.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,42F1U@68295|Thermoanaerobacterales	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRD1_k127_4797555_2	269799.Gmet_1236	9.62e-88	302.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,43TPC@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRD1_k127_4797555_6	1265845.PWEIH_15558	1.068e-22	98.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,26IZ7@186820|Listeriaceae	91061|Bacilli	P	permease	gsiC_2	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRD1_k127_4828156_1	1335760.ASTG01000005_gene981	2.183e-43	165.0	2ADQJ@1|root,313FX@2|Bacteria,1MYNR@1224|Proteobacteria,2UCQS@28211|Alphaproteobacteria,2K5ZN@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4828156_0	1120950.KB892776_gene812	1.992e-43	162.0	COG1670@1|root,COG1670@2|Bacteria,2GP87@201174|Actinobacteria,4DQYP@85009|Propionibacteriales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRD1_k127_4846723_1	1540221.JQNI01000002_gene652	1.507e-39	157.0	COG0791@1|root,COG0791@2|Bacteria,1WJI4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Cell wall-associated hydrolase (invasion-associated protein)	-	-	-	-	-	-	-	-	-	-	-	-	LysM,NLPC_P60
SRD1_k127_4846723_3	720554.Clocl_1792	5.935e-05	52.0	2ECEX@1|root,336D4@2|Bacteria,1VIN1@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4846723_0	266117.Rxyl_1667	3.893e-48	180.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4CQ93@84995|Rubrobacteria	84995|Rubrobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_4846723_2	1944.JOAZ01000007_gene2211	2.605e-09	69.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,419SG@629295|Streptomyces griseus group	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRD1_k127_4870201_3	1089553.Tph_c00160	6.414e-97	335.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia,42EKA@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRD1_k127_4870201_4	316067.Geob_2508	2.006e-94	319.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRD1_k127_4870201_0	1125863.JAFN01000001_gene1711	2.482e-256	807.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRD1_k127_4870201_2	309801.trd_1141	1.55e-101	342.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,2G67J@200795|Chloroflexi,27XXA@189775|Thermomicrobia	189775|Thermomicrobia	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2,5.3.1.9	ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	PGI,TAL_FSA
SRD1_k127_4870201_1	204669.Acid345_2810	1.68e-117	393.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,3Y5VJ@57723|Acidobacteria,2JKZ5@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphoglucose isomerase	-	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRD1_k127_4876231_1	525904.Tter_2326	1.107e-115	381.0	COG1613@1|root,COG1613@2|Bacteria,2NQGY@2323|unclassified Bacteria	2|Bacteria	P	Bacterial extracellular solute-binding protein	subI	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iJN678.sbpA	SBP_bac_11
SRD1_k127_4876231_5	1303518.CCALI_01977	5.566e-14	85.0	COG5493@1|root,COG5493@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4876231_3	1150399.AQYK01000001_gene295	6.351e-34	135.0	COG3832@1|root,COG3832@2|Bacteria,2IKRU@201174|Actinobacteria	201174|Actinobacteria	S	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRD1_k127_4876231_0	1283287.KB822586_gene859	5.511e-176	565.0	COG0531@1|root,COG0531@2|Bacteria,2GIWQ@201174|Actinobacteria,4DNNH@85009|Propionibacteriales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRD1_k127_4876231_2	326424.FRAAL3773	2.584e-54	194.0	COG0229@1|root,COG0229@2|Bacteria,2IHV0@201174|Actinobacteria,4ESRX@85013|Frankiales	201174|Actinobacteria	O	PFAM Methionine sulfoxide reductase B	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRD1_k127_4876231_4	570967.JMLV01000008_gene1364	1.703e-27	118.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,2JQIB@204441|Rhodospirillales	204441|Rhodospirillales	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRD1_k127_4885487_13	318161.Sden_1377	7.947e-15	74.0	COG0346@1|root,COG0346@2|Bacteria,1N08M@1224|Proteobacteria,1SBEZ@1236|Gammaproteobacteria,2QC5U@267890|Shewanellaceae	1236|Gammaproteobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD1_k127_4885487_6	224911.27355033	1.274e-62	217.0	COG5649@1|root,COG5649@2|Bacteria,1RGY3@1224|Proteobacteria,2U9AG@28211|Alphaproteobacteria,3JY3Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRD1_k127_4885487_14	1122217.KB899579_gene1710	2.276e-08	67.0	COG3291@1|root,COG3291@2|Bacteria,1UM7C@1239|Firmicutes,4H9DR@909932|Negativicutes	909932|Negativicutes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4885487_0	1095769.CAHF01000011_gene2062	4.069e-136	452.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VJGK@28216|Betaproteobacteria,473SZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
SRD1_k127_4885487_3	546271.Selsp_0017	3.145e-92	323.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4H359@909932|Negativicutes	909932|Negativicutes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRD1_k127_4885487_10	219305.MCAG_02492	1.339e-23	106.0	COG0718@1|root,COG0718@2|Bacteria,2IRC4@201174|Actinobacteria,4DE90@85008|Micromonosporales	201174|Actinobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRD1_k127_4885487_5	635013.TherJR_0070	2.016e-72	252.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,2612W@186807|Peptococcaceae	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SRD1_k127_4885487_9	1303518.CCALI_02269	1.078e-23	113.0	COG3597@1|root,COG3597@2|Bacteria	2|Bacteria	S	protein domain associated with	ycgC	-	-	ko:K03595,ko:K06883,ko:K06946	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	DUF697,MMR_HSR1
SRD1_k127_4885487_8	580332.Slit_0344	6.346e-32	144.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2WHEI@28216|Betaproteobacteria,44UZ2@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRD1_k127_4885487_11	479434.Sthe_2012	1.82e-23	118.0	COG0850@1|root,COG0850@2|Bacteria,2G6VN@200795|Chloroflexi,27YGI@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C
SRD1_k127_4885487_1	246194.CHY_0348	2.465e-103	342.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia,42FBH@68295|Thermoanaerobacterales	186801|Clostridia	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
SRD1_k127_4885487_4	1195236.CTER_0637	1.797e-82	295.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia,3WH0T@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
SRD1_k127_4885487_12	1121472.AQWN01000006_gene1694	2.803e-18	91.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,262Q3@186807|Peptococcaceae	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
SRD1_k127_4885487_2	1122216.AUHW01000012_gene1559	1.179e-92	316.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4H21I@909932|Negativicutes	909932|Negativicutes	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRD1_k127_4885487_7	1232410.KI421421_gene3878	2.057e-51	187.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2WNA5@28221|Deltaproteobacteria,43UM9@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Redoxin	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
SRD1_k127_4885746_2	1304880.JAGB01000001_gene67	2.997e-110	379.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia	186801|Clostridia	NU	type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRD1_k127_4885746_0	639030.JHVA01000001_gene3811	3.22e-135	438.0	COG0039@1|root,COG0039@2|Bacteria,3Y2PG@57723|Acidobacteria,2JII1@204432|Acidobacteriia	204432|Acidobacteriia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRD1_k127_4885746_1	562970.Btus_2368	1.975e-126	415.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,278TC@186823|Alicyclobacillaceae	91061|Bacilli	C	Citrate synthase, C-terminal domain	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRD1_k127_4914209_1	395965.Msil_2318	5.215e-31	128.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,3NA0H@45404|Beijerinckiaceae	28211|Alphaproteobacteria	E	3-dehydroquinate synthase	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRD1_k127_4914209_0	926550.CLDAP_07310	1.951e-66	243.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2G5K8@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRD1_k127_4914209_2	621372.ACIH01000145_gene125	1.845e-09	69.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,26R54@186822|Paenibacillaceae	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRD1_k127_4917037_0	1382306.JNIM01000001_gene2948	1.171e-113	374.0	COG1087@1|root,COG1087@2|Bacteria,2GA96@200795|Chloroflexi	200795|Chloroflexi	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRD1_k127_4917037_2	1157638.KB892161_gene3121	1.604e-28	125.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRD1_k127_4917037_1	1304880.JAGB01000002_gene2052	3.939e-46	173.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRD1_k127_4929117_1	272630.MexAM1_META1p3038	1.469e-06	53.0	COG0457@1|root,COG1352@1|root,COG0457@2|Bacteria,COG1352@2|Bacteria,1R6N1@1224|Proteobacteria,2U0BX@28211|Alphaproteobacteria,1JSI9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	NT	PFAM MCP methyltransferase CheR-type	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
SRD1_k127_4929117_2	269799.Gmet_3317	3.906e-06	58.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,42T5Y@68525|delta/epsilon subdivisions,2WNT6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	mvhQ	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRD1_k127_4929117_0	1128427.KB904821_gene704	5.131e-45	183.0	COG0840@1|root,COG5278@1|root,COG0840@2|Bacteria,COG5278@2|Bacteria,1G2HD@1117|Cyanobacteria,1H728@1150|Oscillatoriales	1117|Cyanobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CHASE3,MCPsignal
SRD1_k127_4970267_1	1123368.AUIS01000009_gene2508	3.894e-155	505.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria,2NC4Y@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
SRD1_k127_4970267_0	1288494.EBAPG3_21070	2.144e-214	687.0	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,2VN9S@28216|Betaproteobacteria,3720A@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
SRD1_k127_4970267_2	251221.35212929	1.105e-114	393.0	COG0457@1|root,COG0457@2|Bacteria,1G31A@1117|Cyanobacteria	1117|Cyanobacteria	S	tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4970267_3	378806.STAUR_7092	3.525e-59	228.0	COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,42VTI@68525|delta/epsilon subdivisions,2WW2V@28221|Deltaproteobacteria,2YYXY@29|Myxococcales	28221|Deltaproteobacteria	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP
SRD1_k127_4970402_1	316274.Haur_4289	1.658e-79	280.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G7JV@200795|Chloroflexi,375WH@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
SRD1_k127_4970402_2	1144342.PMI40_03276	5.435e-62	226.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2VHPA@28216|Betaproteobacteria,4734U@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Belongs to the pirin family	yhhW_2	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
SRD1_k127_4970402_0	929556.Solca_3407	0.0	1205.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1IRF8@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC
SRD1_k127_4970402_3	913325.N799_13835	7.518e-21	97.0	COG4430@1|root,COG4430@2|Bacteria,1N8ME@1224|Proteobacteria,1T0U8@1236|Gammaproteobacteria,1XD1S@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
SRD1_k127_4987076_12	1605.Lani381_1514	8.879e-05	48.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,3FC7Y@33958|Lactobacillaceae	91061|Bacilli	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRD1_k127_4987076_11	1120958.AULD01000007_gene1127	4.585e-05	53.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4FNEE@85023|Microbacteriaceae	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRD1_k127_4987076_13	1283287.KB822580_gene1701	0.0005457	50.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4DUHE@85009|Propionibacteriales	201174|Actinobacteria	C	ATP synthase B/B' CF(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRD1_k127_4987076_9	1121422.AUMW01000012_gene2907	3.15e-12	70.0	COG0636@1|root,COG0636@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRD1_k127_4987076_7	484770.UFO1_4265	1.238e-35	145.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H33W@909932|Negativicutes	909932|Negativicutes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRD1_k127_4987076_1	1249634.D781_0133	4.89e-124	414.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RPNC@1236|Gammaproteobacteria,3ZZM0@613|Serratia	1236|Gammaproteobacteria	M	Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues	wecB	GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008761,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046378,GO:0071704,GO:1901135,GO:1901137,GO:1901576	3.2.1.183,5.1.3.14	ko:K01791,ko:K08068	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECOK1_1307.ECOK1_4232,iECS88_1305.ECS88_4208,iECs_1301.ECs4719,iEcSMS35_1347.EcSMS35_4150,iG2583_1286.G2583_4580,iPC815.YPO3864,iSDY_1059.SDY_3962,iSSON_1240.SSON_3958,iUMN146_1321.UM146_19070,iZ_1308.Z5297	Epimerase_2
SRD1_k127_4987076_2	1410618.JNKI01000007_gene769	1.094e-73	269.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H2U9@909932|Negativicutes	909932|Negativicutes	M	Glycosyltransferase, group 4 family	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRD1_k127_4987076_5	926550.CLDAP_02830	1.19e-46	181.0	COG2131@1|root,COG2131@2|Bacteria,2G7AC@200795|Chloroflexi	200795|Chloroflexi	F	MafB19-like deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
SRD1_k127_4987076_3	416870.llmg_2176	1.177e-58	211.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli,1YB3N@1357|Lactococcus	91061|Bacilli	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11010	UPRTase
SRD1_k127_4987076_0	1235755.ANAM01000008_gene1610	1.204e-158	518.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,4GY4E@90964|Staphylococcaceae	91061|Bacilli	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRD1_k127_4987076_6	262543.Exig_2695	5.811e-44	164.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,4HGXD@91061|Bacilli,3WFHT@539002|Bacillales incertae sedis	91061|Bacilli	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRD1_k127_4987076_8	941824.TCEL_01227	2.233e-16	85.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia,36JRD@31979|Clostridiaceae	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRD1_k127_4987076_4	1382356.JQMP01000003_gene2059	4.02e-53	200.0	COG0524@1|root,COG0524@2|Bacteria,2G7YB@200795|Chloroflexi,27YGK@189775|Thermomicrobia	189775|Thermomicrobia	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRD1_k127_4987076_10	521674.Plim_0551	1.827e-07	63.0	COG1082@1|root,COG1082@2|Bacteria,2IYUT@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRD1_k127_5031604_2	1121468.AUBR01000044_gene1861	8.172e-62	221.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,42FAS@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRD1_k127_5031604_4	546269.HMPREF0389_00846	1.324e-39	155.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,25QFF@186804|Peptostreptococcaceae	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRD1_k127_5031604_6	592028.GCWU000321_00946	2.38e-19	94.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4H56M@909932|Negativicutes	909932|Negativicutes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRD1_k127_5031604_0	349161.Dred_0218	1.653e-117	388.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,260NI@186807|Peptococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRD1_k127_5031604_3	936589.HMPREF1521_1738	3.486e-41	153.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4H4P6@909932|Negativicutes	909932|Negativicutes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRD1_k127_5031604_5	351627.Csac_2282	4.888e-23	108.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,42GWK@68295|Thermoanaerobacterales	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRD1_k127_5031604_1	1209989.TepiRe1_0209	1.658e-81	278.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,42ERW@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRD1_k127_5065071_4	204669.Acid345_1615	8.488e-23	103.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
SRD1_k127_5065071_1	927677.ALVU02000001_gene2236	2.655e-138	456.0	COG0477@1|root,COG0477@2|Bacteria,1G155@1117|Cyanobacteria	1117|Cyanobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD1_k127_5065071_3	1114922.CIFAM_19_00200	7.969e-56	209.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,1RRG3@1236|Gammaproteobacteria,3WV5R@544|Citrobacter	1236|Gammaproteobacteria	G	Periplasmic binding protein-like domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRD1_k127_5065071_0	1303518.CCALI_01101	6.813e-155	505.0	COG1129@1|root,COG1129@2|Bacteria	2|Bacteria	G	ABC transporter	rbsA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRD1_k127_5065071_2	926561.KB900617_gene1384	1.008e-77	271.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,3WBBT@53433|Halanaerobiales	186801|Clostridia	U	Belongs to the binding-protein-dependent transport system permease family	rbsC	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRD1_k127_509951_3	1122604.JONR01000020_gene449	2.435e-174	562.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1X4Q2@135614|Xanthomonadales	135614|Xanthomonadales	S	transporter	oliA	-	-	-	-	-	-	-	-	-	-	-	OPT
SRD1_k127_509951_10	452637.Oter_1866	5.62e-16	82.0	COG0346@1|root,COG0346@2|Bacteria,46YKH@74201|Verrucomicrobia,3K9S9@414999|Opitutae	414999|Opitutae	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD1_k127_509951_6	2002.JOEQ01000012_gene5606	8.067e-60	216.0	COG0697@1|root,COG0697@2|Bacteria,2GM50@201174|Actinobacteria,4EQYN@85012|Streptosporangiales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRD1_k127_509951_4	232721.Ajs_2676	6.072e-103	350.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VIPR@28216|Betaproteobacteria,4AA3P@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRD1_k127_509951_2	395961.Cyan7425_1168	3.33e-257	815.0	COG4953@1|root,COG4953@2|Bacteria,1G428@1117|Cyanobacteria,3KJSD@43988|Cyanothece	1117|Cyanobacteria	M	PFAM glycosyl transferase family 51	pbpB	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
SRD1_k127_509951_0	1173028.ANKO01000171_gene3843	0.0	1809.0	COG2373@1|root,COG2373@2|Bacteria,1G1A1@1117|Cyanobacteria,1H8RT@1150|Oscillatoriales	1117|Cyanobacteria	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,CarboxypepD_reg,MG1,Thiol-ester_cl
SRD1_k127_509951_8	948106.AWZT01000001_gene5061	9.518e-35	142.0	2DBDP@1|root,32TXA@2|Bacteria,1NRJC@1224|Proteobacteria,2W125@28216|Betaproteobacteria,1K3D5@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_509951_9	1162668.LFE_1557	1.506e-16	89.0	COG0723@1|root,COG1873@1|root,COG0723@2|Bacteria,COG1873@2|Bacteria,3J0TT@40117|Nitrospirae	40117|Nitrospirae	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
SRD1_k127_509951_5	330214.NIDE3889	1.347e-83	297.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3J0Q6@40117|Nitrospirae	2|Bacteria	C	Cytochrome b/b6/petB	qcrC	-	-	ko:K00412,ko:K03888	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B,Cytochrome_CBB3
SRD1_k127_509951_7	237368.SCABRO_00501	3.361e-38	147.0	COG2154@1|root,COG2154@2|Bacteria,2J0CT@203682|Planctomycetes	203682|Planctomycetes	H	PFAM Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRD1_k127_509951_1	59538.XP_005977342.1	1.269e-282	877.0	COG0422@1|root,2QRQ4@2759|Eukaryota,38I15@33154|Opisthokonta,3BNVW@33208|Metazoa	33208|Metazoa	H	Phosphomethylpyrimidine synthase, chloroplastic-like	-	-	-	-	-	-	-	-	-	-	-	-	ThiC-associated,ThiC_Rad_SAM
SRD1_k127_5106611_2	1248916.ANFY01000003_gene999	6.623e-26	115.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TRTE@28211|Alphaproteobacteria,2K0PD@204457|Sphingomonadales	204457|Sphingomonadales	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRD1_k127_5106611_0	861299.J421_6282	3.601e-149	497.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
SRD1_k127_5106611_1	861299.J421_0786	3.093e-46	186.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZT4G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRD1_k127_5112075_4	1408433.JHXV01000024_gene1488	2.432e-17	96.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Exostosin,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
SRD1_k127_5112075_0	871963.Desdi_3237	1.882e-168	540.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,248NW@186801|Clostridia,2606B@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRD1_k127_5112075_3	743525.TSC_c03010	1.658e-24	110.0	COG1086@1|root,COG1086@2|Bacteria,1WIQA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
SRD1_k127_5112075_1	398511.BpOF4_06615	8.638e-102	349.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,4HAER@91061|Bacilli,1ZB9K@1386|Bacillus	91061|Bacilli	GM	Polysaccharide biosynthesis protein	pglF	GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192	-	ko:K19421	-	-	-	-	ko00000	-	-	-	CoA_binding_3,Polysacc_synt_2
SRD1_k127_5112075_2	1173023.KE650771_gene4257	2.323e-62	240.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1G00H@1117|Cyanobacteria,1JJ7W@1189|Stigonemataceae	1117|Cyanobacteria	D	G-rich domain on putative tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
SRD1_k127_5112075_5	56110.Oscil6304_1683	2.981e-07	59.0	COG1596@1|root,COG1596@2|Bacteria,1G0AJ@1117|Cyanobacteria,1H8T2@1150|Oscillatoriales	1117|Cyanobacteria	M	COG1596 Periplasmic protein involved in polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRD1_k127_5116057_5	479432.Sros_5694	2.069e-40	155.0	COG2103@1|root,COG2103@2|Bacteria,2GN0K@201174|Actinobacteria,4EGI1@85012|Streptosporangiales	201174|Actinobacteria	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
SRD1_k127_5116057_4	314278.NB231_14818	1.164e-42	167.0	2EZ43@1|root,33SAA@2|Bacteria,1NRHB@1224|Proteobacteria,1SN43@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5116057_2	1455608.JDTH01000011_gene2262	1.918e-89	312.0	COG2377@1|root,2N56F@2157|Archaea,2Y2SX@28890|Euryarchaeota,23Z3Y@183963|Halobacteria	183963|Halobacteria	O	Anhydro-N-acetylmuramic acid kinase	-	-	-	-	-	-	-	-	-	-	-	-	AnmK
SRD1_k127_5116057_3	292459.STH302	6.739e-60	222.0	COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,249GA@186801|Clostridia	186801|Clostridia	V	Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRD1_k127_5116057_1	1122915.AUGY01000074_gene4353	1.242e-92	325.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,26RMX@186822|Paenibacillaceae	91061|Bacilli	G	Glycoside hydrolase family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
SRD1_k127_5116057_6	1123368.AUIS01000030_gene1253	1.009e-24	106.0	COG1522@1|root,COG1522@2|Bacteria,1NC1H@1224|Proteobacteria,1SE9N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRD1_k127_5116057_0	661478.OP10G_4167	3.569e-94	317.0	COG2107@1|root,COG2107@2|Bacteria	2|Bacteria	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K07083,ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRD1_k127_5116057_7	263820.PTO0507	3.326e-21	108.0	COG2151@1|root,arCOG01845@2157|Archaea,2Y0P6@28890|Euryarchaeota,242AR@183967|Thermoplasmata	183967|Thermoplasmata	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRD1_k127_5189535_9	1123288.SOV_2c12050	8.758e-30	121.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,4H87J@909932|Negativicutes	909932|Negativicutes	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRD1_k127_5189535_7	68570.DC74_1206	9.247e-32	131.0	2FFBI@1|root,34797@2|Bacteria,2IK51@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5189535_3	204669.Acid345_1484	1.094e-77	284.0	COG4733@1|root,COG4993@1|root,COG4733@2|Bacteria,COG4993@2|Bacteria,3Y2WV@57723|Acidobacteria,2JKWV@204432|Acidobacteriia	204432|Acidobacteriia	G	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ
SRD1_k127_5189535_2	1295642.H839_18055	3.665e-136	446.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,1WFN6@129337|Geobacillus	91061|Bacilli	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRD1_k127_5189535_1	760568.Desku_3546	3.483e-235	751.0	COG1067@1|root,COG1067@2|Bacteria,1TP2K@1239|Firmicutes,247TX@186801|Clostridia,26043@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the peptidase S16 family	lonC	-	3.4.21.53	ko:K01338,ko:K04076	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,Lon_C,RuvB_N
SRD1_k127_5189535_6	697329.Rumal_1645	8.08e-35	138.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,3WJCC@541000|Ruminococcaceae	186801|Clostridia	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRD1_k127_5189535_10	401526.TcarDRAFT_0863	4.49e-29	117.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4H53V@909932|Negativicutes	909932|Negativicutes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRD1_k127_5189535_8	445972.ANACOL_04434	2.161e-30	124.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,3WJAP@541000|Ruminococcaceae	186801|Clostridia	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRD1_k127_5189535_12	1121430.JMLG01000002_gene1303	2.776e-19	91.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,262KE@186807|Peptococcaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRD1_k127_5189535_11	1125863.JAFN01000001_gene3024	6.889e-24	108.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRD1_k127_5189535_14	1356854.N007_09255	9.429e-14	84.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SRD1_k127_5189535_5	1125863.JAFN01000001_gene1545	1.708e-37	156.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2WIVG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRD1_k127_5189535_4	562970.Btus_0996	5.672e-47	173.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,278GH@186823|Alicyclobacillaceae	91061|Bacilli	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRD1_k127_5189535_0	635013.TherJR_1206	1.308e-265	835.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,260Q8@186807|Peptococcaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
SRD1_k127_5189535_13	105420.BBPO01000011_gene1946	7.707e-16	88.0	COG5653@1|root,COG5653@2|Bacteria,2IKIG@201174|Actinobacteria,2NKDP@228398|Streptacidiphilus	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SRD1_k127_5207845_3	981369.JQMJ01000004_gene1085	2.46e-56	211.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,2NKRD@228398|Streptacidiphilus	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRD1_k127_5207845_2	309801.trd_A0197	5.314e-68	244.0	COG1573@1|root,COG1573@2|Bacteria,2G8DF@200795|Chloroflexi,27YTA@189775|Thermomicrobia	189775|Thermomicrobia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRD1_k127_5207845_4	1121033.AUCF01000014_gene1213	4.887e-54	203.0	COG0111@1|root,COG0111@2|Bacteria,1R5FD@1224|Proteobacteria,2U0C0@28211|Alphaproteobacteria,2JSER@204441|Rhodospirillales	204441|Rhodospirillales	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
SRD1_k127_5207845_5	1120936.KB907219_gene3105	8.209e-41	161.0	COG0500@1|root,COG2226@2|Bacteria,2I35J@201174|Actinobacteria,4EIVJ@85012|Streptosporangiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRD1_k127_5207845_0	1131269.AQVV01000016_gene1845	2.428e-121	405.0	COG1249@1|root,COG1249@2|Bacteria	2|Bacteria	C	cell redox homeostasis	pdhD	-	1.16.1.1,1.8.1.4	ko:K00382,ko:K00520	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRD1_k127_5207845_1	298653.Franean1_1105	5.643e-76	270.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4ERX7@85013|Frankiales	201174|Actinobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRD1_k127_5207845_6	1123489.AUAN01000011_gene1450	1.428e-06	58.0	29Y8S@1|root,30K2H@2|Bacteria,1V5XQ@1239|Firmicutes,4H4EX@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5274949_0	926560.KE387023_gene1931	4.922e-118	387.0	COG0160@1|root,COG0160@2|Bacteria,1WIP2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_5274949_1	1117379.BABA_09926	2.063e-66	229.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4HBY4@91061|Bacilli,1ZE30@1386|Bacillus	91061|Bacilli	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.82	ko:K09251	ko00330,ko01100,map00330,map01100	-	R01155	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_5307784_0	670292.JH26_11480	9.467e-67	234.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1MVQY@1224|Proteobacteria,2U070@28211|Alphaproteobacteria,1JT5J@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRD1_k127_5307784_1	290315.Clim_2256	1.387e-14	82.0	2E8QS@1|root,3331S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5349145_0	485913.Krac_2434	1.567e-247	779.0	COG1529@1|root,COG1529@2|Bacteria,2G5NF@200795|Chloroflexi	2|Bacteria	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRD1_k127_5349145_1	1382306.JNIM01000001_gene1024	2.394e-85	310.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRD1_k127_5349145_2	235985.BBPN01000040_gene354	6.411e-81	271.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,2NKRD@228398|Streptacidiphilus	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRD1_k127_5355494_5	765420.OSCT_0539	7.591e-41	152.0	COG3808@1|root,COG3808@2|Bacteria,2G5N7@200795|Chloroflexi,376RW@32061|Chloroflexia	32061|Chloroflexia	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRD1_k127_5355494_8	290397.Adeh_0209	3.357e-23	113.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42MBR@68525|delta/epsilon subdivisions,2WJ0Z@28221|Deltaproteobacteria,2YZA5@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1238	Peptidase_M48,TPR_14,TPR_16,TPR_19
SRD1_k127_5355494_1	1218103.CIN01S_05_00100	2.728e-125	419.0	COG0477@1|root,COG2814@2|Bacteria,4NG27@976|Bacteroidetes,1IJ7T@117743|Flavobacteriia,3ZP5U@59732|Chryseobacterium	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
SRD1_k127_5355494_6	289376.THEYE_A1348	2.144e-39	151.0	COG0222@1|root,COG0222@2|Bacteria,3J0NQ@40117|Nitrospirae	40117|Nitrospirae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRD1_k127_5355494_7	1064535.MELS_0401	3.694e-34	140.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4H4W8@909932|Negativicutes	909932|Negativicutes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRD1_k127_5355494_2	264732.Moth_2471	2.074e-84	287.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,42ETC@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRD1_k127_5355494_4	592015.HMPREF1705_01568	2.163e-60	211.0	COG0080@1|root,COG0080@2|Bacteria,3TB1G@508458|Synergistetes	508458|Synergistetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRD1_k127_5355494_3	997346.HMPREF9374_2817	2.438e-69	248.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli,27BM8@186824|Thermoactinomycetaceae	91061|Bacilli	K	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRD1_k127_5355494_9	479437.Elen_2132	3.117e-16	81.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4CWGB@84998|Coriobacteriia	84998|Coriobacteriia	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRD1_k127_5355494_0	656519.Halsa_1923	7.984e-200	627.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WAAG@53433|Halanaerobiales	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRD1_k127_5361504_1	243231.GSU3369	6.313e-93	323.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,43S0Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRD1_k127_5361504_3	292459.STH2404	2.932e-34	135.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRD1_k127_5361504_0	1121430.JMLG01000002_gene1328	8.096e-310	970.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,2601Z@186807|Peptococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRD1_k127_5361504_5	317619.ANKN01000079_gene167	1.77e-24	112.0	COG0802@1|root,COG0802@2|Bacteria,1GDUE@1117|Cyanobacteria,1MMB7@1212|Prochloraceae	1117|Cyanobacteria	S	to have essential role in cell wall biosynthesis	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRD1_k127_5361504_7	391600.ABRU01000005_gene1651	1.745e-10	73.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2TTM2@28211|Alphaproteobacteria,2KGSU@204458|Caulobacterales	204458|Caulobacterales	O	PFAM peptidase M22 glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRD1_k127_5361504_2	1382304.JNIL01000001_gene2610	1.637e-41	164.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,278GA@186823|Alicyclobacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRD1_k127_5361504_4	1123511.KB905845_gene2883	1.362e-30	129.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4H4ES@909932|Negativicutes	909932|Negativicutes	H	Hydrolase HD family	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRD1_k127_5361504_6	1157490.EL26_00980	3.027e-22	103.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,278I1@186823|Alicyclobacillaceae	91061|Bacilli	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRD1_k127_5370640_1	1131269.AQVV01000048_gene2100	4.335e-68	241.0	COG0457@1|root,COG0457@2|Bacteria	1131269.AQVV01000048_gene2100|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5370640_0	234267.Acid_3622	7.245e-86	299.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRD1_k127_5398889_1	1123368.AUIS01000026_gene1459	1.345e-43	160.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,1RNWU@1236|Gammaproteobacteria,2NCT5@225057|Acidithiobacillales	225057|Acidithiobacillales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRD1_k127_5398889_3	314230.DSM3645_06946	2.746e-07	64.0	COG4206@1|root,COG4206@2|Bacteria,2IY7Z@203682|Planctomycetes	203682|Planctomycetes	H	TonB-dependent Receptor Plug Domain	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
SRD1_k127_5398889_0	1121468.AUBR01000016_gene2302	1.641e-106	375.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia,42F9D@68295|Thermoanaerobacterales	186801|Clostridia	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRD1_k127_5398889_2	1121468.AUBR01000016_gene2303	1.949e-31	128.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,42F61@68295|Thermoanaerobacterales	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1,4.3.1.29	ko:K01042,ko:K17468	ko00030,ko00450,ko00970,ko01120,map00030,map00450,map00970,map01120	-	R08219,R10408	RC00544,RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRD1_k127_5407629_3	1385517.N800_09760	4.861e-07	62.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,1X4WG@135614|Xanthomonadales	135614|Xanthomonadales	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRD1_k127_5407629_1	682795.AciX8_4872	3.238e-29	119.0	COG0776@1|root,COG0776@2|Bacteria,3Y5E1@57723|Acidobacteria,2JJN0@204432|Acidobacteriia	204432|Acidobacteriia	L	Bacterial DNA-binding protein	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRD1_k127_5407629_4	666681.M301_1661	3.318e-06	52.0	2DFEC@1|root,2ZRJ8@2|Bacteria,1P53J@1224|Proteobacteria,2W5GD@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2934
SRD1_k127_5407629_0	1122138.AQUZ01000002_gene2101	3.568e-32	138.0	arCOG10517@1|root,31Y5Z@2|Bacteria,2IN0B@201174|Actinobacteria,4DV9U@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5407629_2	1459636.NTE_02825	4.451e-08	64.0	arCOG03383@1|root,arCOG03383@2157|Archaea	2157|Archaea	E	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRD1_k127_5420298_1	1034345.CAEM01000017_gene1645	1.461e-34	146.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria,4CUQR@84998|Coriobacteriia	84998|Coriobacteriia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
SRD1_k127_5420298_0	720554.Clocl_1485	9.947e-85	292.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WGS4@541000|Ruminococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRD1_k127_5428810_4	604354.TSIB_0893	1.048e-26	117.0	COG1171@1|root,arCOG01431@2157|Archaea,2XT4W@28890|Euryarchaeota	28890|Euryarchaeota	E	Threonine dehydratase	ilvA2	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4,PALP
SRD1_k127_5428810_0	760568.Desku_1657	0.0	1050.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRD1_k127_5428810_3	1121468.AUBR01000012_gene2571	3.636e-36	151.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24PNN@186801|Clostridia,42JDW@68295|Thermoanaerobacterales	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRD1_k127_5428810_5	548477.HMPREF0294_1681	4.565e-07	60.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,22MQI@1653|Corynebacteriaceae	201174|Actinobacteria	D	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRD1_k127_5428810_2	523791.Kkor_0693	2.407e-108	366.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1XH70@135619|Oceanospirillales	135619|Oceanospirillales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRD1_k127_5428810_1	292459.STH1219	5.365e-136	441.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRD1_k127_5428810_6	517417.Cpar_1643	6.291e-06	57.0	COG1051@1|root,COG1051@2|Bacteria,1FDZM@1090|Chlorobi	1090|Chlorobi	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRD1_k127_5428810_7	1054860.KB913030_gene486	0.000179	51.0	COG3832@1|root,COG3832@2|Bacteria,2IHQS@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRD1_k127_5450135_0	322710.Avin_39770	2.643e-74	267.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRD1_k127_5450135_3	1121344.JHZO01000001_gene485	2.328e-10	65.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,24UH5@186801|Clostridia	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRD1_k127_5450135_1	401526.TcarDRAFT_1595	2.695e-63	228.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4H37C@909932|Negativicutes	909932|Negativicutes	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRD1_k127_5450135_2	264732.Moth_1509	2.216e-37	151.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,42FQN@68295|Thermoanaerobacterales	186801|Clostridia	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
SRD1_k127_5461802_7	1121372.AULK01000004_gene1341	9.502e-09	60.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4FMBT@85023|Microbacteriaceae	201174|Actinobacteria	H	intramolecular transferase activity, transferring amino groups	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_5461802_2	1382359.JIAL01000001_gene29	3.053e-42	160.0	COG2128@1|root,COG2128@2|Bacteria,3Y8IA@57723|Acidobacteria,2JNES@204432|Acidobacteriia	204432|Acidobacteriia	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRD1_k127_5461802_3	309801.trd_1718	2.357e-40	165.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi,27XRJ@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRD1_k127_5461802_0	401526.TcarDRAFT_1875	5.926e-116	395.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD1_k127_5461802_1	484770.UFO1_1578	1.279e-82	308.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD1_k127_5461802_6	485913.Krac_8476	1.07e-12	75.0	COG3794@1|root,COG3794@2|Bacteria,2G7GX@200795|Chloroflexi	200795|Chloroflexi	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRD1_k127_5461802_4	1121377.KB906402_gene3238	7.048e-40	169.0	COG0860@1|root,COG0860@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
SRD1_k127_5461802_5	243230.DR_1530	5.855e-17	86.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRD1_k127_5461802_8	592015.HMPREF1705_00505	1.2e-08	60.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PrlF_antitoxin
SRD1_k127_5467930_0	264732.Moth_2309	3.906e-123	407.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,42FKX@68295|Thermoanaerobacterales	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRD1_k127_5480607_1	1123023.JIAI01000028_gene4487	4.967e-145	486.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4E035@85010|Pseudonocardiales	201174|Actinobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRD1_k127_5480607_7	330214.NIDE0819	3.851e-05	56.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	omp-1X	-	-	ko:K12976,ko:K22110	-	-	-	-	ko00000,ko01000,ko01005,ko02000	1.B.35.1,1.B.35.2	-	-	DUF2490,OMP_b-brl,Surface_Ag_2
SRD1_k127_5480607_6	1382304.JNIL01000001_gene3215	9.597e-15	78.0	COG1622@1|root,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cupredoxin_1
SRD1_k127_5480607_0	1007103.AFHW01000154_gene1038	9.55e-165	536.0	COG0843@1|root,COG0843@2|Bacteria,1TPZC@1239|Firmicutes,4HAHT@91061|Bacilli,26SCU@186822|Paenibacillaceae	91061|Bacilli	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRD1_k127_5480607_2	562970.Btus_0425	3.043e-51	186.0	COG1622@1|root,COG1622@2|Bacteria,1TPMD@1239|Firmicutes,4HGXU@91061|Bacilli,279W5@186823|Alicyclobacillaceae	91061|Bacilli	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
SRD1_k127_5480607_5	479433.Caci_2191	1.101e-32	132.0	COG1733@1|root,COG1733@2|Bacteria,2IQWP@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRD1_k127_5480607_3	621372.ACIH01000037_gene738	7.164e-36	142.0	COG2259@1|root,COG2259@2|Bacteria,1V7TX@1239|Firmicutes,4HJ1T@91061|Bacilli,26YB6@186822|Paenibacillaceae	91061|Bacilli	S	PFAM DoxX family protein	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRD1_k127_5480607_4	945713.IALB_0843	1.103e-34	147.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,Laminin_G_3
SRD1_k127_5508881_1	1122604.JONR01000011_gene3720	4.452e-63	233.0	COG4733@1|root,COG4934@1|root,COG4733@2|Bacteria,COG4934@2|Bacteria,1R98B@1224|Proteobacteria,1SN5E@1236|Gammaproteobacteria,1X58I@135614|Xanthomonadales	135614|Xanthomonadales	O	Pro-kumamolisin, activation domain	-	-	3.4.21.101	ko:K05999	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PKD,Peptidase_S8,Pro-kuma_activ
SRD1_k127_5508881_0	1082933.MEA186_18517	1.643e-157	505.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2TT55@28211|Alphaproteobacteria,43JJ3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	soxF	-	1.8.2.3,1.8.5.4	ko:K17218,ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499,R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2
SRD1_k127_5508881_2	1267533.KB906737_gene1647	1.933e-19	90.0	2F8FQ@1|root,340UE@2|Bacteria,3Y87C@57723|Acidobacteria,2JNC9@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5521449_3	367299.JOEE01000012_gene3258	4.333e-18	96.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,4FHUI@85021|Intrasporangiaceae	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRD1_k127_5521449_0	309799.DICTH_1914	2.865e-138	455.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRD1_k127_5521449_1	1379698.RBG1_1C00001G1510	2.946e-81	289.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldE2	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRD1_k127_5521449_2	1128421.JAGA01000002_gene119	2.781e-64	227.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRD1_k127_5527051_2	670487.Ocepr_0101	0.0001257	55.0	COG2010@1|root,COG2010@2|Bacteria,1WIF2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
SRD1_k127_5527051_0	1382306.JNIM01000001_gene3727	5.72e-69	256.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	ko:K08677	-	-	-	-	ko00000,ko01002	-	-	-	He_PIG,Peptidase_S8,Pro-kuma_activ
SRD1_k127_55322_0	317936.Nos7107_1512	3.707e-125	433.0	COG5549@1|root,COG5549@2|Bacteria,1G2AK@1117|Cyanobacteria,1HICN@1161|Nostocales	1117|Cyanobacteria	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
SRD1_k127_55322_1	429009.Adeg_0011	7.228e-95	316.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,42EYY@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRD1_k127_5532850_0	1125863.JAFN01000001_gene750	1.683e-105	349.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
SRD1_k127_5532850_1	478741.JAFS01000002_gene820	1.244e-93	317.0	COG0502@1|root,COG0502@2|Bacteria,46SFX@74201|Verrucomicrobia,37GES@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Biotin and Thiamin Synthesis associated domain	-	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
SRD1_k127_5536471_0	926561.KB900617_gene1784	1.081e-216	686.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3WA95@53433|Halanaerobiales	186801|Clostridia	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRD1_k127_5536471_1	1123288.SOV_5c00340	3.651e-33	146.0	COG4942@1|root,COG4942@2|Bacteria,1UWVQ@1239|Firmicutes,4H6EV@909932|Negativicutes	909932|Negativicutes	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRD1_k127_5536471_2	292459.STH3328	1.447e-17	89.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
SRD1_k127_5547136_0	646529.Desaci_2684	4.964e-149	484.0	COG0531@1|root,COG0531@2|Bacteria,1TQ41@1239|Firmicutes	1239|Firmicutes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRD1_k127_5547136_1	204669.Acid345_3113	3.993e-127	420.0	COG0665@1|root,COG0665@2|Bacteria,3Y8UA@57723|Acidobacteria	57723|Acidobacteria	E	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRD1_k127_5547136_2	266117.Rxyl_2356	1.465e-55	199.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria,4CQ7H@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRD1_k127_5547136_3	1463820.JOGW01000001_gene5570	1.669e-06	58.0	COG1846@1|root,COG1846@2|Bacteria,2INEU@201174|Actinobacteria	201174|Actinobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5547136_4	497964.CfE428DRAFT_2307	0.0003823	50.0	COG0810@1|root,COG0810@2|Bacteria,46WNS@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRD1_k127_5563092_0	1041930.Mtc_1294	1.427e-142	464.0	COG1914@1|root,arCOG04531@2157|Archaea,2XU6H@28890|Euryarchaeota,2NASS@224756|Methanomicrobia	224756|Methanomicrobia	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
SRD1_k127_5563092_1	1304874.JAFY01000002_gene765	5.191e-08	66.0	COG2508@1|root,COG2508@2|Bacteria,3TBP3@508458|Synergistetes	508458|Synergistetes	K	PFAM purine catabolism	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
SRD1_k127_556410_5	485915.Dret_1657	1.652e-06	59.0	COG0810@1|root,COG0810@2|Bacteria,1NDQZ@1224|Proteobacteria,42VIY@68525|delta/epsilon subdivisions,2WRTC@28221|Deltaproteobacteria,2MDBG@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRD1_k127_556410_1	1183438.GKIL_1156	9.66e-108	363.0	COG1473@1|root,COG1473@2|Bacteria,1G01G@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Peptidase family M20 M25 M40	ama	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRD1_k127_556410_0	1123368.AUIS01000002_gene1535	2.341e-137	459.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,2NCHN@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRD1_k127_556410_3	56107.Cylst_4497	9.09e-38	156.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria,1HJSM@1161|Nostocales	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
SRD1_k127_556410_4	351607.Acel_0165	9.942e-36	158.0	COG2199@1|root,COG2203@1|root,COG5000@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG5000@2|Bacteria,2IA4H@201174|Actinobacteria	201174|Actinobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HAMP
SRD1_k127_556410_2	234267.Acid_2875	1.265e-68	241.0	COG3844@1|root,COG3844@2|Bacteria,3Y984@57723|Acidobacteria	57723|Acidobacteria	F	Aminotransferase class-V	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRD1_k127_5592992_8	1396141.BATP01000059_gene2427	1.263e-23	104.0	COG0346@1|root,COG0346@2|Bacteria,46VWA@74201|Verrucomicrobia,2IVZP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD1_k127_5592992_6	1121022.ABENE_11570	1.886e-51	192.0	COG0730@1|root,COG0730@2|Bacteria,1RCVI@1224|Proteobacteria,2U5XM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane transporter protein	MA20_18170	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRD1_k127_5592992_7	640081.Dsui_1987	6.699e-47	180.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,2VMUD@28216|Betaproteobacteria,2KVNG@206389|Rhodocyclales	206389|Rhodocyclales	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRD1_k127_5592992_0	1234364.AMSF01000079_gene1847	0.0	1055.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,1RZK1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRD1_k127_5592992_3	926560.KE387027_gene854	2.813e-62	227.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRD1_k127_5592992_5	469383.Cwoe_1923	1.825e-54	215.0	COG1680@1|root,COG1680@2|Bacteria,2IGJ4@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRD1_k127_5592992_4	1380394.JADL01000002_gene1597	3.149e-55	199.0	COG0053@1|root,COG0053@2|Bacteria,1ND3V@1224|Proteobacteria,2U3WH@28211|Alphaproteobacteria,2JWFJ@204441|Rhodospirillales	204441|Rhodospirillales	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SRD1_k127_5592992_9	1122939.ATUD01000004_gene3928	3.197e-13	75.0	COG0346@1|root,COG0346@2|Bacteria,2HRG5@201174|Actinobacteria,4CTF6@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD1_k127_5592992_1	1267534.KB906760_gene1403	3.16e-154	511.0	COG3975@1|root,COG3975@2|Bacteria,3Y411@57723|Acidobacteria,2JI4Z@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase M61	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
SRD1_k127_5592992_2	1242864.D187_003813	4.969e-66	235.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2YU4K@29|Myxococcales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRD1_k127_5598550_2	1303518.CCALI_01413	2.694e-114	391.0	COG0417@1|root,COG0417@2|Bacteria	2|Bacteria	L	DNA replication proofreading	polB	-	2.7.7.7	ko:K02336,ko:K06877,ko:K07501	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	CarbopepD_reg_2,DNA_pol_B,DNA_pol_B_exo1,DNA_pol_B_exo2,RNase_H_2
SRD1_k127_5598550_6	321327.CYA_0625	2.084e-43	175.0	COG2755@1|root,COG2755@2|Bacteria,1GPBT@1117|Cyanobacteria,1H2U8@1129|Synechococcus	1117|Cyanobacteria	E	GDSL-like lipase acylhydrolase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRD1_k127_5598550_14	671143.DAMO_1273	0.0001391	53.0	COG1276@1|root,COG1276@2|Bacteria	2|Bacteria	P	copper resistance	-	-	-	ko:K07245,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	AhpC-TSA,CopC,CopD,Cyt-b5,Cytochrome_CBB3
SRD1_k127_5598550_1	469383.Cwoe_5866	4.829e-148	478.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4CQTG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,QRPTase_C,QRPTase_N
SRD1_k127_5598550_0	671143.DAMO_2750	1.29e-152	501.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2NNNK@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase X family	polX	-	-	ko:K02347,ko:K04477	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRD1_k127_5598550_8	717605.Theco_2195	1.414e-29	132.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,4HB6B@91061|Bacilli,26S37@186822|Paenibacillaceae	91061|Bacilli	J	Metal-dependent phosphoesterase	php	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
SRD1_k127_5598550_4	264732.Moth_1038	9.12e-72	249.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,42F7X@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRD1_k127_5598550_9	1123229.AUBC01000006_gene821	5.032e-29	129.0	COG0640@1|root,COG0640@2|Bacteria,1R9XP@1224|Proteobacteria,2U5PE@28211|Alphaproteobacteria,3JY7B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Winged helix DNA-binding domain	MA20_23570	-	-	-	-	-	-	-	-	-	-	-	HTH_34
SRD1_k127_5598550_12	1187851.A33M_1875	2.521e-17	89.0	2BACU@1|root,323T9@2|Bacteria,1R49S@1224|Proteobacteria,2TSC0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5598550_3	867845.KI911784_gene2100	1.018e-101	344.0	COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi,37550@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRD1_k127_5598550_10	765420.OSCT_1231	4.123e-21	107.0	COG3437@1|root,COG3437@2|Bacteria,2G6QF@200795|Chloroflexi,37587@32061|Chloroflexia	200795|Chloroflexi	KT	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
SRD1_k127_5598550_7	484770.UFO1_4750	7.458e-32	137.0	COG2367@1|root,COG2367@2|Bacteria,1UYZ3@1239|Firmicutes,4H4VY@909932|Negativicutes	909932|Negativicutes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRD1_k127_5598550_11	558169.AGAV01000003_gene2660	8.142e-21	98.0	COG0010@1|root,COG0010@2|Bacteria,1TR10@1239|Firmicutes,4HAT5@91061|Bacilli	91061|Bacilli	E	Belongs to the arginase family	rocF	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRD1_k127_5598550_5	1007103.AFHW01000073_gene5508	1.312e-56	202.0	COG0010@1|root,COG0010@2|Bacteria,1TR10@1239|Firmicutes,4HAT5@91061|Bacilli,26SVB@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the arginase family	rocF	GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRD1_k127_5598550_13	410358.Mlab_0998	2.005e-05	57.0	COG0306@1|root,arCOG02267@2157|Archaea,2XSUU@28890|Euryarchaeota,2N9TT@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRD1_k127_5601623_3	1192034.CAP_6279	3.1e-26	111.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WINR@28221|Deltaproteobacteria,2YX29@29|Myxococcales	28221|Deltaproteobacteria	H	Aminotransferase class-III	-	-	2.6.1.55,2.6.1.77	ko:K03851,ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684,R05652	RC00006,RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_5601623_1	378806.STAUR_1586	2.119e-160	522.0	COG1012@1|root,COG1012@2|Bacteria,1QWN5@1224|Proteobacteria,43BT3@68525|delta/epsilon subdivisions,2X73T@28221|Deltaproteobacteria,2YYMR@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRD1_k127_5601623_0	1297742.A176_05941	2.817e-167	539.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_5601623_2	1297742.A176_05942	5.251e-119	409.0	COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,42S03@68525|delta/epsilon subdivisions,2WNW5@28221|Deltaproteobacteria,2YZ59@29|Myxococcales	28221|Deltaproteobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRD1_k127_5659052_2	445971.ANASTE_01533	6.339e-36	142.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,25WN4@186806|Eubacteriaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRD1_k127_5659052_0	1183438.GKIL_3351	6.543e-39	156.0	COG0681@1|root,COG0681@2|Bacteria,1G519@1117|Cyanobacteria	1117|Cyanobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRD1_k127_5659052_1	1183438.GKIL_3351	1.881e-38	153.0	COG0681@1|root,COG0681@2|Bacteria,1G519@1117|Cyanobacteria	1117|Cyanobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRD1_k127_5677462_2	1144275.COCOR_00427	3.146e-142	458.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,42MY6@68525|delta/epsilon subdivisions,2WMDC@28221|Deltaproteobacteria,2YU5V@29|Myxococcales	28221|Deltaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD1_k127_5677462_0	479434.Sthe_0456	2.2e-209	667.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi,27XPW@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
SRD1_k127_5677462_3	1382359.JIAL01000001_gene2805	3.697e-12	68.0	2A08Y@1|root,30NC8@2|Bacteria,3Y8UU@57723|Acidobacteria,2JNQ5@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF3311)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3311
SRD1_k127_5677462_1	1120971.AUCA01000022_gene539	1.177e-164	532.0	COG0591@1|root,COG0591@2|Bacteria,1UZRF@1239|Firmicutes,4HGPN@91061|Bacilli	91061|Bacilli	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SRD1_k127_5691470_0	292459.STH1598	2.08e-74	269.0	COG1007@1|root,COG1007@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRD1_k127_5691470_1	1550091.JROE01000010_gene3249	1.469e-06	53.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1IPJW@117747|Sphingobacteriia	976|Bacteroidetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRD1_k127_5720091_0	379066.GAU_0662	3.386e-39	160.0	COG0438@1|root,COG0438@2|Bacteria,1ZU1H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD1_k127_5720091_1	103733.JNYO01000056_gene1104	1.821e-38	155.0	COG0438@1|root,COG0438@2|Bacteria,2GK9J@201174|Actinobacteria,4EEG6@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRD1_k127_5729329_1	743299.Acife_2012	8.235e-75	261.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,1RMKB@1236|Gammaproteobacteria,2NBRA@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
SRD1_k127_5729329_0	1163617.SCD_n00704	0.0	1193.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2VIGM@28216|Betaproteobacteria	28216|Betaproteobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRD1_k127_5729329_2	886293.Sinac_3333	2.819e-58	210.0	COG2193@1|root,COG2193@2|Bacteria,2J19B@203682|Planctomycetes	203682|Planctomycetes	P	Ferritin-like domain	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRD1_k127_5729329_3	1500890.JQNL01000001_gene364	4.065e-38	150.0	COG3145@1|root,COG3145@2|Bacteria,1RGXU@1224|Proteobacteria,1S6DD@1236|Gammaproteobacteria,1X6V0@135614|Xanthomonadales	135614|Xanthomonadales	L	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
SRD1_k127_573497_2	1037409.BJ6T_27860	2.391e-64	222.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2TTHB@28211|Alphaproteobacteria,3JSA2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF899)	MA20_01595	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRD1_k127_573497_1	1007103.AFHW01000032_gene2246	4.353e-94	316.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRD1_k127_573497_0	1408473.JHXO01000002_gene3931	5.311e-96	324.0	COG0604@1|root,COG0604@2|Bacteria,4NHHT@976|Bacteroidetes,2FR11@200643|Bacteroidia	976|Bacteroidetes	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_2,ADH_zinc_N_2
SRD1_k127_573497_3	1123024.AUII01000028_gene2493	1.01e-23	104.0	COG0596@1|root,COG0596@2|Bacteria,2HEMJ@201174|Actinobacteria,4DYUK@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRD1_k127_5752752_4	868131.MSWAN_1817	2.981e-66	229.0	COG5485@1|root,arCOG06513@2157|Archaea,2Y3E5@28890|Euryarchaeota	28890|Euryarchaeota	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRD1_k127_5752752_3	234267.Acid_6257	9.633e-95	334.0	COG1520@1|root,COG4934@1|root,COG1520@2|Bacteria,COG4934@2|Bacteria,3Y99I@57723|Acidobacteria	57723|Acidobacteria	O	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Lectin_legB
SRD1_k127_5752752_1	1382306.JNIM01000001_gene1825	1.164e-143	473.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	yhdG_2	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,HATPase_c,HisKA,Response_reg
SRD1_k127_5752752_0	118168.MC7420_6877	3.503e-173	570.0	COG1012@1|root,COG1012@2|Bacteria,1G046@1117|Cyanobacteria,1H7Q6@1150|Oscillatoriales	1117|Cyanobacteria	C	PFAM Aldehyde dehydrogenase	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	iECDH10B_1368.gabD,iJN678.gabD	Aldedh
SRD1_k127_5752752_5	1163409.UUA_13310	2.558e-54	199.0	2EZ43@1|root,33SAA@2|Bacteria,1NRHB@1224|Proteobacteria,1SN43@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5752752_6	285514.JNWO01000003_gene7063	4.675e-30	124.0	COG3324@1|root,COG3324@2|Bacteria,2IKX6@201174|Actinobacteria	201174|Actinobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD1_k127_5752752_2	1160718.SU9_04471	1.606e-100	335.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRD1_k127_5789755_0	635013.TherJR_0289	0.0	1405.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,260I2@186807|Peptococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRD1_k127_5850757_2	706587.Desti_2109	5.976e-57	205.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria,2MRG0@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRD1_k127_5850757_1	1382356.JQMP01000003_gene1988	4.399e-120	393.0	COG1023@1|root,COG1023@2|Bacteria,2G5YD@200795|Chloroflexi,27XH5@189775|Thermomicrobia	189775|Thermomicrobia	C	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRD1_k127_5850757_0	309801.trd_1143	3.509e-181	596.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,27XRX@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRD1_k127_5850757_3	756067.MicvaDRAFT_1256	5.136e-18	96.0	COG3409@1|root,COG3429@1|root,COG3409@2|Bacteria,COG3429@2|Bacteria,1G2UB@1117|Cyanobacteria,1H7B9@1150|Oscillatoriales	1117|Cyanobacteria	GM	PFAM Glucose-6-phosphate dehydrogenase subunit	opcA	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem,PG_binding_1
SRD1_k127_5859588_0	526227.Mesil_3494	1.662e-73	268.0	COG0642@1|root,COG2205@2|Bacteria,1WKYX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Osmosensitive K channel His kinase sensor domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	KdpD,Usp
SRD1_k127_5862618_3	886293.Sinac_3064	7.165e-10	60.0	COG0136@1|root,COG0136@2|Bacteria,2IY8G@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRD1_k127_5862618_1	635013.TherJR_0357	3.38e-83	292.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,260TF@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRD1_k127_5862618_0	1499680.CCFE01000030_gene3666	9.264e-88	300.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,1ZBNR@1386|Bacillus	91061|Bacilli	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRD1_k127_5862618_2	335541.Swol_2372	7.325e-53	203.0	COG1922@1|root,COG1922@2|Bacteria,1V3QV@1239|Firmicutes,24AQ3@186801|Clostridia,42KEJ@68298|Syntrophomonadaceae	186801|Clostridia	F	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
SRD1_k127_5885520_1	644282.Deba_2451	7.082e-120	410.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions,2WUPM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K06446	ko00930,ko01100,ko01120,map00930,map01100,map01120	-	R06943	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_5885520_0	1379698.RBG1_1C00001G0785	8.839e-121	405.0	COG1541@1|root,COG1541@2|Bacteria,2NREC@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
SRD1_k127_5892913_3	864051.BurJ1DRAFT_1265	1.981e-08	60.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2VIY9@28216|Betaproteobacteria,1KK25@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Polysaccharide biosynthesis/export protein	epsE	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRD1_k127_5892913_4	1463881.KL591004_gene3698	4.473e-08	61.0	COG2197@1|root,COG2197@2|Bacteria,2GJ9U@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRD1_k127_5892913_0	926569.ANT_02390	3.021e-111	374.0	COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi	200795|Chloroflexi	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRD1_k127_5892913_1	1173026.Glo7428_0892	6.261e-82	285.0	28IVI@1|root,2Z8TY@2|Bacteria,1G87H@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
SRD1_k127_5892913_2	366602.Caul_4805	2.806e-25	119.0	COG1215@1|root,COG1215@2|Bacteria,1NDPE@1224|Proteobacteria,2TSCT@28211|Alphaproteobacteria,2KG2I@204458|Caulobacterales	204458|Caulobacterales	M	Glycosyl transferase family group 2	-	-	-	ko:K16557	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRD1_k127_5937403_6	1123276.KB893251_gene3585	0.0001619	49.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47JK5@768503|Cytophagia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRD1_k127_5937403_5	1089547.KB913013_gene4627	1.417e-06	61.0	COG0745@1|root,COG0745@2|Bacteria,4NGNK@976|Bacteroidetes,47M5N@768503|Cytophagia	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_5937403_0	1267535.KB906767_gene2422	2.062e-147	484.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,GSDH,HYR,He_PIG,Laminin_G_3,Malectin,NPCBM
SRD1_k127_5937403_1	195250.CM001776_gene122	3.59e-69	248.0	COG0657@1|root,COG0657@2|Bacteria,1G229@1117|Cyanobacteria,1H2KY@1129|Synechococcus	1117|Cyanobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRD1_k127_5937403_2	118166.JH976537_gene419	9.52e-32	143.0	COG3409@1|root,COG3409@2|Bacteria,1GQNA@1117|Cyanobacteria	1117|Cyanobacteria	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
SRD1_k127_5937403_3	485913.Krac_9009	8.458e-24	104.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1,MFS_3
SRD1_k127_5959377_2	644966.Tmar_0397	3.683e-23	103.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	1.1.1.103,1.1.1.14	ko:K00008,ko:K00060	ko00040,ko00051,ko00260,ko01100,map00040,map00051,map00260,map01100	M00014	R00875,R01465,R01896	RC00085,RC00102,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD1_k127_5959377_1	391009.Tmel_1918	2.944e-39	154.0	COG0599@1|root,COG0599@2|Bacteria,2GD25@200918|Thermotogae	200918|Thermotogae	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRD1_k127_5959377_0	316274.Haur_1907	5.373e-79	274.0	COG2084@1|root,COG2084@2|Bacteria,2G6B3@200795|Chloroflexi,376B1@32061|Chloroflexia	32061|Chloroflexia	I	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRD1_k127_5959377_3	1500897.JQNA01000002_gene82	0.0001467	55.0	COG2199@1|root,COG2199@2|Bacteria,1R1PW@1224|Proteobacteria,2W4KC@28216|Betaproteobacteria	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRD1_k127_597062_1	1267534.KB906755_gene4040	1.828e-66	235.0	COG0491@1|root,COG0491@2|Bacteria,3Y4DN@57723|Acidobacteria,2JJ36@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRD1_k127_597062_0	1345697.M493_10975	1.895e-70	253.0	COG0318@1|root,COG0318@2|Bacteria,1UKBR@1239|Firmicutes,4ITH5@91061|Bacilli,1WH7V@129337|Geobacillus	91061|Bacilli	IQ	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
SRD1_k127_597062_2	742159.HMPREF0004_0191	6.113e-12	77.0	COG1012@1|root,COG1012@2|Bacteria,1R656@1224|Proteobacteria,2VPB8@28216|Betaproteobacteria,3T6PT@506|Alcaligenaceae	28216|Betaproteobacteria	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
SRD1_k127_5974840_1	1379698.RBG1_1C00001G0798	8.255e-129	434.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
SRD1_k127_5974840_4	42256.RradSPS_0295	1.222e-60	217.0	COG2316@1|root,COG2316@2|Bacteria,2GSXZ@201174|Actinobacteria,4CQ0P@84995|Rubrobacteria	84995|Rubrobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRD1_k127_5974840_2	864069.MicloDRAFT_00051220	8.573e-74	258.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,1JX36@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRD1_k127_5974840_0	234267.Acid_7156	1.262e-177	576.0	COG3882@1|root,COG3882@2|Bacteria	2|Bacteria	Q	phosphopantetheine binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5974840_6	234267.Acid_7809	1.793e-07	57.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRD1_k127_5974840_5	931276.Cspa_c45510	2.318e-15	83.0	COG0110@1|root,COG0110@2|Bacteria,1TPKX@1239|Firmicutes,249X2@186801|Clostridia,36DHA@31979|Clostridiaceae	186801|Clostridia	S	Acetyltransferase (Isoleucine patch superfamily)	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
SRD1_k127_5974840_3	693986.MOC_1432	1.133e-60	220.0	COG1028@1|root,COG2030@1|root,COG1028@2|Bacteria,COG2030@2|Bacteria,1QT7I@1224|Proteobacteria,2V1TP@28211|Alphaproteobacteria,1JXKN@119045|Methylobacteriaceae	28211|Alphaproteobacteria	IQ	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas,adh_short
SRD1_k127_5979583_3	28444.JODQ01000008_gene966	2.243e-11	66.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4EI2I@85012|Streptosporangiales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.17.1.9,1.6.5.3	ko:K00122,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
SRD1_k127_5979583_0	1237500.ANBA01000003_gene4800	4.111e-222	700.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4EGXK@85012|Streptosporangiales	201174|Actinobacteria	C	Molybdopterin oxidoreductase	fdnG	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
SRD1_k127_5979583_2	1121385.AQXW01000004_gene1611	1.196e-30	126.0	COG3383@1|root,COG3383@2|Bacteria,2GWFF@201174|Actinobacteria	201174|Actinobacteria	C	Molybdopterin oxidoreductase	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin
SRD1_k127_5979583_1	1009370.ALO_07088	1.794e-60	228.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,4H3J2@909932|Negativicutes	909932|Negativicutes	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
SRD1_k127_597964_2	1341151.ASZU01000003_gene2690	1.158e-77	269.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,27BBV@186824|Thermoactinomycetaceae	91061|Bacilli	F	Phosphorylase superfamily	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRD1_k127_597964_1	1121428.DESHY_110553___1	2.164e-88	314.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,2605U@186807|Peptococcaceae	186801|Clostridia	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRD1_k127_597964_0	1144275.COCOR_05004	6.715e-113	375.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,42P5X@68525|delta/epsilon subdivisions,2WIQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRD1_k127_597964_3	391623.TERMP_00885	2.09e-49	185.0	COG0463@1|root,arCOG00895@2157|Archaea,2Y66T@28890|Euryarchaeota,2454F@183968|Thermococci	183968|Thermococci	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD1_k127_597964_5	1121438.JNJA01000021_gene1340	1.882e-34	147.0	COG1216@1|root,COG1216@2|Bacteria,1R11B@1224|Proteobacteria,43D5D@68525|delta/epsilon subdivisions,2X8C3@28221|Deltaproteobacteria,2MA1N@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
SRD1_k127_597964_7	1247963.JPHU01000002_gene2497	3.294e-10	71.0	COG1216@1|root,COG1216@2|Bacteria,1RHVX@1224|Proteobacteria,2UA24@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD1_k127_597964_8	106370.Francci3_1050	2.928e-05	57.0	COG1572@1|root,COG1572@2|Bacteria,2I56C@201174|Actinobacteria,4EXBH@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF3367)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3367
SRD1_k127_597964_6	479434.Sthe_0849	1.675e-19	102.0	COG0438@1|root,COG0438@2|Bacteria,2G8W3@200795|Chloroflexi,27Y3X@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
SRD1_k127_597964_4	1121949.AQXT01000002_gene1905	2.271e-37	155.0	COG1216@1|root,COG1216@2|Bacteria,1R6SJ@1224|Proteobacteria,2U47V@28211|Alphaproteobacteria,43W7J@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRD1_k127_599905_2	338963.Pcar_2316	3.724e-33	134.0	COG0745@1|root,COG0745@2|Bacteria,1N1N5@1224|Proteobacteria,42UP1@68525|delta/epsilon subdivisions,2WQAF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRD1_k127_599905_1	525904.Tter_1673	6.055e-53	198.0	COG2185@1|root,COG2185@2|Bacteria,2NPGA@2323|unclassified Bacteria	2|Bacteria	I	Cobalamin B12-binding	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRD1_k127_599905_0	204669.Acid345_1454	8.905e-232	729.0	COG1884@1|root,COG1884@2|Bacteria,3Y2PQ@57723|Acidobacteria,2JHJN@204432|Acidobacteriia	204432|Acidobacteriia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRD1_k127_6010872_0	479434.Sthe_3117	2.939e-207	663.0	COG4447@1|root,COG4447@2|Bacteria,2G678@200795|Chloroflexi	200795|Chloroflexi	S	PFAM glycosyl hydrolase BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRD1_k127_6010872_2	1380394.JADL01000002_gene1628	1.94e-34	136.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2UC5C@28211|Alphaproteobacteria,2JXIK@204441|Rhodospirillales	204441|Rhodospirillales	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SRD1_k127_6010872_1	929556.Solca_0694	4.872e-58	209.0	COG3548@1|root,COG3548@2|Bacteria,4NPIF@976|Bacteroidetes,1IS6F@117747|Sphingobacteriia	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRD1_k127_6010872_3	693986.MOC_4621	5.136e-12	66.0	COG1926@1|root,COG2312@1|root,COG1926@2|Bacteria,COG2312@2|Bacteria,1RAG8@1224|Proteobacteria,2U5HS@28211|Alphaproteobacteria,1JTD3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
SRD1_k127_6021333_3	497964.CfE428DRAFT_0726	2.093e-23	102.0	28JZ9@1|root,2Z9PC@2|Bacteria,46TB7@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6021333_5	1219031.BBJR01000046_gene1852	0.0002263	49.0	COG2823@1|root,COG2823@2|Bacteria,1NIM8@1224|Proteobacteria,2VX5E@28216|Betaproteobacteria,4AJJ9@80864|Comamonadaceae	28216|Betaproteobacteria	S	SMART Transport-associated and nodulation	-	-	-	-	-	-	-	-	-	-	-	-	BON
SRD1_k127_6021333_4	935836.JAEL01000201_gene4586	2.199e-06	53.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6021333_1	986075.CathTA2_2930	3.054e-93	323.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli	91061|Bacilli	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRD1_k127_6021333_2	945713.IALB_1708	2.904e-78	266.0	COG0740@1|root,COG0740@2|Bacteria	2|Bacteria	OU	serine-type endopeptidase activity	clpP	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRD1_k127_6021333_0	555079.Toce_1766	2.596e-196	619.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,42EU3@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRD1_k127_6023489_0	1069080.KB913028_gene948	9.018e-241	763.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4H20K@909932|Negativicutes	909932|Negativicutes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRD1_k127_6023489_14	584708.Apau_1579	2.29e-30	131.0	COG1555@1|root,COG1555@2|Bacteria,3TB6C@508458|Synergistetes	508458|Synergistetes	L	TIGRFAM competence protein ComEA	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRD1_k127_6023489_10	1234364.AMSF01000033_gene404	6.69e-65	241.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,1X3VH@135614|Xanthomonadales	135614|Xanthomonadales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRD1_k127_6023489_11	1101192.KB910516_gene1048	2.095e-62	224.0	COG4117@1|root,COG4117@2|Bacteria,1MX97@1224|Proteobacteria,2U0ZF@28211|Alphaproteobacteria,1JRBK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
SRD1_k127_6023489_9	1267534.KB906755_gene4824	1.917e-65	231.0	2AY4N@1|root,31Q6J@2|Bacteria,3Y7H6@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6023489_4	1121946.AUAX01000019_gene7834	7.253e-94	319.0	COG0520@1|root,COG0520@2|Bacteria,2GJA4@201174|Actinobacteria,4DC2F@85008|Micromonosporales	201174|Actinobacteria	E	aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRD1_k127_6023489_17	1379698.RBG1_1C00001G0763	1.524e-24	117.0	COG2885@1|root,COG5276@1|root,COG2885@2|Bacteria,COG5276@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
SRD1_k127_6023489_2	861299.J421_0396	1.692e-113	377.0	COG1028@1|root,COG1028@2|Bacteria,1ZV1D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD1_k127_6023489_12	861299.J421_0395	4.921e-59	209.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Glutaredoxin
SRD1_k127_6023489_1	469383.Cwoe_5284	3.948e-197	640.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4CP7M@84995|Rubrobacteria	84995|Rubrobacteria	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRD1_k127_6023489_8	1131269.AQVV01000001_gene1358	8.427e-71	252.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
SRD1_k127_6023489_5	330214.NIDE2527	6.745e-90	304.0	COG2048@1|root,COG2048@2|Bacteria,3J175@40117|Nitrospirae	40117|Nitrospirae	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K00241,ko:K03389	ko00020,ko00190,ko00650,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00356,M00357,M00374,M00376,M00563,M00567	R02164,R04540,R11928,R11931,R11943,R11944	RC00011,RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
SRD1_k127_6023489_3	864069.MicloDRAFT_00055390	1.133e-112	368.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria,1JUHK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	C-terminal domain of 1-Cys peroxiredoxin	MA20_35715	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRD1_k127_6023489_13	443598.AUFA01000013_gene6543	4.903e-57	203.0	2C4SR@1|root,32TC7@2|Bacteria,1RCZG@1224|Proteobacteria,2U89H@28211|Alphaproteobacteria,3JZY4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6023489_6	1382304.JNIL01000001_gene276	2.988e-87	297.0	COG3511@1|root,COG3511@2|Bacteria,1U22R@1239|Firmicutes,4HCD7@91061|Bacilli,279H4@186823|Alicyclobacillaceae	91061|Bacilli	M	Phosphoesterase family	-	-	3.1.3.64	ko:K21302	ko00562,ko01100,ko05152,map00562,map01100,map05152	-	-	-	ko00000,ko00001,ko01000	-	-	-	Phosphoesterase
SRD1_k127_6023489_15	1089548.KI783301_gene1487	1.812e-26	119.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli,3WDX3@539002|Bacillales incertae sedis	91061|Bacilli	S	Mitochondrial PGP phosphatase	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
SRD1_k127_6023489_7	643473.KB235930_gene1874	4.126e-72	256.0	COG1597@1|root,COG1597@2|Bacteria,1G0MV@1117|Cyanobacteria,1HM0P@1161|Nostocales	1117|Cyanobacteria	I	TIGRFAM lipid kinase, YegS Rv2252 BmrU family	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRD1_k127_6023489_16	983917.RGE_26570	7.542e-26	116.0	2DIFQ@1|root,30348@2|Bacteria,1N288@1224|Proteobacteria,2W1RB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6023489_18	455632.SGR_6804	3.478e-06	59.0	COG2730@1|root,COG3386@1|root,COG2730@2|Bacteria,COG3386@2|Bacteria,2HEPQ@201174|Actinobacteria,4186X@629295|Streptomyces griseus group	201174|Actinobacteria	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,RicinB_lectin_2
SRD1_k127_6028097_2	909663.KI867150_gene2400	1.111e-86	317.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,42N99@68525|delta/epsilon subdivisions,2WJY8@28221|Deltaproteobacteria,2MR7E@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRD1_k127_6028097_0	479434.Sthe_0985	1.268e-160	519.0	COG0277@1|root,COG0277@2|Bacteria,2G5TM@200795|Chloroflexi,27XF8@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRD1_k127_6028097_4	479434.Sthe_0986	2.141e-53	205.0	COG0277@1|root,COG0277@2|Bacteria,2G6FW@200795|Chloroflexi,27XX4@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
SRD1_k127_6028097_1	383372.Rcas_4296	1.428e-108	370.0	COG0247@1|root,COG0247@2|Bacteria,2G5V8@200795|Chloroflexi,37729@32061|Chloroflexia	32061|Chloroflexia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
SRD1_k127_6028097_3	1487953.JMKF01000041_gene3085	1.166e-58	212.0	COG1409@1|root,COG1409@2|Bacteria,1G32R@1117|Cyanobacteria,1HABV@1150|Oscillatoriales	1117|Cyanobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
SRD1_k127_6028097_5	215803.DB30_3248	7.086e-07	54.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,42R96@68525|delta/epsilon subdivisions,2WMVV@28221|Deltaproteobacteria,2YXAR@29|Myxococcales	28221|Deltaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRD1_k127_6049902_3	293826.Amet_4191	1.999e-17	93.0	COG2971@1|root,COG2971@2|Bacteria,1V0VG@1239|Firmicutes,24BFK@186801|Clostridia,36WXX@31979|Clostridiaceae	186801|Clostridia	G	BadF BadG BcrA BcrD ATPase family	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRD1_k127_6049902_1	981369.JQMJ01000004_gene1085	1.032e-131	434.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,2NKRD@228398|Streptacidiphilus	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRD1_k127_6049902_0	1207063.P24_05054	3.196e-202	638.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2TSAC@28211|Alphaproteobacteria,2JPB4@204441|Rhodospirillales	204441|Rhodospirillales	I	Acyl-CoA dehydrogenase, middle domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_6049902_2	384765.SIAM614_09923	4.361e-24	103.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2U9A9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRD1_k127_6065463_3	1123508.JH636439_gene885	9.595e-10	64.0	COG0712@1|root,COG0712@2|Bacteria,2J09A@203682|Planctomycetes	203682|Planctomycetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRD1_k127_6065463_0	525904.Tter_0065	1.815e-208	659.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRD1_k127_6065463_2	370438.PTH_2813	1.625e-64	230.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,2601T@186807|Peptococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRD1_k127_6065463_1	871963.Desdi_3438	3.723e-170	540.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,260A2@186807|Peptococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRD1_k127_6073835_3	1128421.JAGA01000004_gene2703	1.695e-56	212.0	COG1167@1|root,COG1167@2|Bacteria,2NQG7@2323|unclassified Bacteria	2|Bacteria	EK	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	lysN	-	1.1.3.46,2.6.1.103	ko:K00375,ko:K05825,ko:K16422,ko:K16423	ko00261,ko00300,ko01055,ko01100,ko01130,ko01210,map00261,map00300,map01055,map01100,map01130,map01210	-	R01939,R06626,R06633,R06634	RC00006,RC00240,RC01104	ko00000,ko00001,ko01000,ko03000	-	-	-	Aminotran_1_2,GntR
SRD1_k127_6073835_5	373994.Riv7116_0516	4.813e-15	81.0	COG0454@1|root,COG0456@2|Bacteria,1G6YM@1117|Cyanobacteria,1HP6F@1161|Nostocales	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD1_k127_6073835_1	1297742.A176_02052	3.21e-64	226.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,42MR4@68525|delta/epsilon subdivisions,2WM3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity	aqpZ	-	-	ko:K02440,ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.2	-	-	MIP
SRD1_k127_6073835_0	234267.Acid_0755	8.637e-145	485.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,3Y3IF@57723|Acidobacteria	57723|Acidobacteria	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
SRD1_k127_6073835_2	1111069.TCCBUS3UF1_820	6.605e-58	214.0	COG1028@1|root,COG1028@2|Bacteria,1WKWV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD1_k127_6073835_4	68194.JNXR01000004_gene4308	4.534e-42	167.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF11
SRD1_k127_6075582_5	648996.Theam_0358	7.656e-24	116.0	COG1333@1|root,COG1333@2|Bacteria,2G400@200783|Aquificae	200783|Aquificae	O	ResB family	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
SRD1_k127_6075582_4	309801.trd_1617	6.298e-28	123.0	COG0805@1|root,COG0805@2|Bacteria,2G6SP@200795|Chloroflexi,27XZG@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRD1_k127_6075582_7	1227499.C493_02843	2.709e-06	52.0	COG1826@1|root,arCOG02694@2157|Archaea,2Y04A@28890|Euryarchaeota,23Y7M@183963|Halobacteria	183963|Halobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRD1_k127_6075582_3	767434.Fraau_2995	2.2e-48	195.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1X32F@135614|Xanthomonadales	135614|Xanthomonadales	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRD1_k127_6075582_1	1540221.JQNI01000002_gene2425	1.511e-52	194.0	COG0500@1|root,COG2226@2|Bacteria,1WIUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRD1_k127_6075582_6	637389.Acaty_c1773	1.516e-06	59.0	COG1502@1|root,COG1502@2|Bacteria,1R9I4@1224|Proteobacteria,1RZ86@1236|Gammaproteobacteria,2NC1C@225057|Acidithiobacillales	225057|Acidithiobacillales	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRD1_k127_6075582_0	926560.KE387026_gene4174	7.108e-80	275.0	COG1131@1|root,COG1131@2|Bacteria,1WI6M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_6075582_2	926560.KE387026_gene4175	4.73e-50	197.0	COG0842@1|root,COG0842@2|Bacteria,1WM4H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
SRD1_k127_6092671_5	1179773.BN6_61220	2.072e-13	74.0	COG2197@1|root,COG2197@2|Bacteria,2IG2E@201174|Actinobacteria,4E2V8@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD1_k127_6092671_4	1379698.RBG1_1C00001G0893	1.145e-19	96.0	COG1309@1|root,COG1309@2|Bacteria,2NS0M@2323|unclassified Bacteria	2|Bacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
SRD1_k127_6092671_2	1125863.JAFN01000001_gene2446	1.126e-34	142.0	COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,42NZQ@68525|delta/epsilon subdivisions,2WMCW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD1_k127_6092671_1	1379698.RBG1_1C00001G0907	4.687e-100	338.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	bamA	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788	3.7.1.21	ko:K07539,ko:K18570	ko00332,ko00362,ko01100,ko01120,ko01130,ko01220,map00332,map00362,map01100,map01120,map01130,map01220	M00541	R05593,R05594,R10696,R10750	RC01430,RC01431,RC03237,RC03270	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD1_k127_6092671_0	1379698.RBG1_1C00001G0892	3.862e-127	420.0	COG1062@1|root,COG1062@2|Bacteria	2|Bacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N
SRD1_k127_6092671_3	1187851.A33M_3196	5.676e-22	98.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2U2IH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
SRD1_k127_6126021_5	1183438.GKIL_1804	3.386e-11	68.0	COG0841@1|root,COG0841@2|Bacteria,1G0C2@1117|Cyanobacteria	1117|Cyanobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRD1_k127_6126021_3	370438.PTH_2786	9.634e-28	128.0	COG0845@1|root,COG0845@2|Bacteria,1V2JZ@1239|Firmicutes,24A5A@186801|Clostridia,261XD@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_D23
SRD1_k127_6126021_6	521011.Mpal_2074	3.285e-09	68.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea	2157|Archaea	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Lipase_GDSL_2,NHL,NosD,PKD,Peptidase_C1,Peptidase_S8,Tail_P2_I
SRD1_k127_6126021_2	886882.PPSC2_c2923	3.604e-29	135.0	COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes,4HADE@91061|Bacilli,26QMB@186822|Paenibacillaceae	91061|Bacilli	S	haloacid dehalogenase	ysaA	-	3.1.3.5,3.8.1.2	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287	RC00017,RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRD1_k127_6126021_4	292414.TM1040_2881	8.577e-22	100.0	COG5480@1|root,COG5480@2|Bacteria,1RISQ@1224|Proteobacteria,2U9NW@28211|Alphaproteobacteria,4NDBJ@97050|Ruegeria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1036)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1036
SRD1_k127_6126021_0	1009370.ALO_19192	0.0	1261.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4H24Z@909932|Negativicutes	909932|Negativicutes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRD1_k127_6126021_1	518766.Rmar_1222	1.11e-149	487.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1FJ26@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRD1_k127_6133945_3	518766.Rmar_1802	1.759e-65	236.0	COG1834@1|root,COG1834@2|Bacteria,4PECN@976|Bacteroidetes,1FIVN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
SRD1_k127_6133945_6	644283.Micau_1481	7.454e-45	169.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4D8XR@85008|Micromonosporales	201174|Actinobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRD1_k127_6133945_9	887898.HMPREF0551_0360	1.102e-16	83.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2VHIP@28216|Betaproteobacteria,1JZTJ@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRD1_k127_6133945_5	555088.DealDRAFT_2421	7.382e-53	197.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,42JUU@68298|Syntrophomonadaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
SRD1_k127_6133945_4	264732.Moth_1052	5.788e-54	205.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,42ER4@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM phosphoesterase, RecJ domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRD1_k127_6133945_8	743719.PaelaDRAFT_1536	1.49e-25	110.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,26YF0@186822|Paenibacillaceae	91061|Bacilli	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRD1_k127_6133945_11	391625.PPSIR1_08531	3.203e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,1Q2SX@1224|Proteobacteria,438EQ@68525|delta/epsilon subdivisions,2X3PN@28221|Deltaproteobacteria,2YWSJ@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_7,TPR_8
SRD1_k127_6133945_0	1121430.JMLG01000001_gene2148	1.458e-220	711.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,260ER@186807|Peptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRD1_k127_6133945_10	264732.Moth_1048	3.026e-08	59.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,42H84@68295|Thermoanaerobacterales	186801|Clostridia	K	Protein of unknown function (DUF448)	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SRD1_k127_6133945_1	635013.TherJR_1374	6.115e-118	394.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,2604E@186807|Peptococcaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRD1_k127_6133945_7	1121472.AQWN01000005_gene2382	1.32e-29	132.0	COG3437@1|root,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,260BC@186807|Peptococcaceae	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS_4
SRD1_k127_6133945_2	485913.Krac_2592	3.15e-68	235.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6161048_0	1382306.JNIM01000001_gene721	2.542e-108	360.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi	200795|Chloroflexi	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF1858,ParA
SRD1_k127_6161048_3	1192034.CAP_1569	2.641e-31	134.0	COG3332@1|root,COG3332@2|Bacteria,1PUN1@1224|Proteobacteria,434TB@68525|delta/epsilon subdivisions,2WZ4B@28221|Deltaproteobacteria,2Z1AV@29|Myxococcales	28221|Deltaproteobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
SRD1_k127_6161048_2	1382306.JNIM01000001_gene1703	1.682e-76	273.0	COG0683@1|root,COG0683@2|Bacteria,2G6Q3@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRD1_k127_6161048_1	42256.RradSPS_1811	4.668e-88	300.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4CPRG@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K11956	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	BPD_transp_2
SRD1_k127_6184165_2	861299.J421_4339	2.359e-08	59.0	2E74N@1|root,331P2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6184165_0	867845.KI911784_gene457	1.769e-148	483.0	COG4638@1|root,COG4638@2|Bacteria,2G720@200795|Chloroflexi,377BT@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.14.15.7	ko:K00479,ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
SRD1_k127_6184165_1	240015.ACP_0487	2.685e-71	247.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6213843_4	479434.Sthe_1689	1.542e-05	50.0	COG1385@1|root,COG1385@2|Bacteria,2G70G@200795|Chloroflexi,27YEX@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRD1_k127_6213843_3	1254432.SCE1572_24060	2.801e-28	123.0	COG4221@1|root,COG4221@2|Bacteria,1PWXN@1224|Proteobacteria,43811@68525|delta/epsilon subdivisions,2X3B3@28221|Deltaproteobacteria,2YV70@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4336)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4336
SRD1_k127_6213843_2	186497.PF0058	1.128e-54	203.0	COG0463@1|root,arCOG00894@2157|Archaea,2XWXA@28890|Euryarchaeota,242RY@183968|Thermococci	183968|Thermococci	M	GtrA-like protein	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
SRD1_k127_6213843_0	1121377.KB906401_gene3528	2.354e-82	283.0	COG0777@1|root,COG0777@2|Bacteria,1WIB7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRD1_k127_6213843_1	1120973.AQXL01000122_gene177	7.258e-76	263.0	COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli,2782P@186823|Alicyclobacillaceae	91061|Bacilli	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SRD1_k127_6218056_1	1382304.JNIL01000001_gene1756	1.725e-131	449.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRD1_k127_6218056_0	926562.Oweho_0452	1.054e-138	480.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,2PBDA@246874|Cryomorphaceae	976|Bacteroidetes	V	The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRD1_k127_6218056_5	1267534.KB906760_gene1243	7.015e-05	57.0	COG1629@1|root,COG1629@2|Bacteria,3Y98Z@57723|Acidobacteria,2JI5U@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRD1_k127_6218056_2	861299.J421_0542	4.419e-79	274.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRD1_k127_6218056_4	204669.Acid345_0006	4.366e-50	181.0	COG1970@1|root,COG1970@2|Bacteria,3Y58F@57723|Acidobacteria,2JJRP@204432|Acidobacteriia	204432|Acidobacteriia	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRD1_k127_6218056_3	1121013.P873_08950	9.105e-79	271.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,1RN0M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
SRD1_k127_6225604_2	123214.PERMA_1134	5.552e-40	151.0	COG0074@1|root,COG0074@2|Bacteria,2G3R8@200783|Aquificae	200783|Aquificae	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRD1_k127_6225604_0	469383.Cwoe_5543	9.869e-104	351.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CPVD@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRD1_k127_6225604_1	796606.BMMGA3_16170	2.571e-44	166.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HA2A@91061|Bacilli,1ZBG3@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	mmgC	-	-	ko:K18244	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_6248818_2	1380394.JADL01000002_gene1077	4.547e-43	178.0	28J52@1|root,2Z90Y@2|Bacteria,1R3XK@1224|Proteobacteria,2U3J8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6248818_0	760568.Desku_3333	5.341e-117	386.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,26045@186807|Peptococcaceae	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRD1_k127_6248818_1	1380390.JIAT01000011_gene2279	1.017e-57	200.0	COG4312@1|root,COG4312@2|Bacteria,2GIVC@201174|Actinobacteria,4CPYH@84995|Rubrobacteria	84995|Rubrobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRD1_k127_6255609_2	1123288.SOV_1c11360	2.246e-06	61.0	COG1629@1|root,COG4771@2|Bacteria,1UK22@1239|Firmicutes,4H7DK@909932|Negativicutes	909932|Negativicutes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRD1_k127_6255609_0	880073.Calab_1563	1.739e-12	81.0	COG1629@1|root,COG1629@2|Bacteria,2NS4U@2323|unclassified Bacteria	2|Bacteria	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SRD1_k127_6255609_1	1121930.AQXG01000001_gene1523	2.269e-09	71.0	COG1629@1|root,COG4771@2|Bacteria,4NTQD@976|Bacteroidetes,1J0XF@117747|Sphingobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SRD1_k127_6296933_2	1242864.D187_005182	8.61e-65	232.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria,2YV3C@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRD1_k127_6296933_1	1120971.AUCA01000041_gene2430	7.996e-93	314.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,278T5@186823|Alicyclobacillaceae	91061|Bacilli	D	Cellulose biosynthesis protein BcsQ	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRD1_k127_6296933_0	1379698.RBG1_1C00001G0474	1.116e-93	324.0	COG0617@1|root,COG0617@2|Bacteria,2NPB4@2323|unclassified Bacteria	2|Bacteria	J	Poly A polymerase head domain	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRD1_k127_6296933_3	1089553.Tph_c00300	8.618e-35	142.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,42FAQ@68295|Thermoanaerobacterales	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRD1_k127_6296933_4	1111479.AXAR01000002_gene2023	3.413e-07	53.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,277VE@186823|Alicyclobacillaceae	91061|Bacilli	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
SRD1_k127_6330533_3	330214.NIDE3486	0.000285	48.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD1_k127_6330533_0	1437824.BN940_12326	8.212e-41	160.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,2VKUI@28216|Betaproteobacteria,3T2H9@506|Alcaligenaceae	28216|Betaproteobacteria	M	Glycosyl transferase family 2	lgtF	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
SRD1_k127_6330533_1	309801.trd_0658	6.203e-34	149.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi,27XSF@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD1_k127_6330533_2	511051.CSE_02610	2.123e-05	55.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771,ko:K07126	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Cu_amine_oxidN1,TPR_2,TPR_8,Trypsin_2,YceG_bac
SRD1_k127_6332599_3	324602.Caur_3617	1.165e-30	130.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRD1_k127_6332599_4	1122604.JONR01000018_gene1038	5.158e-26	115.0	COG1309@1|root,COG1309@2|Bacteria,1NCT4@1224|Proteobacteria	1224|Proteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD1_k127_6332599_1	1183438.GKIL_2106	2.946e-52	200.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
SRD1_k127_6332599_0	929556.Solca_0145	3.518e-53	195.0	2E5NA@1|root,330D3@2|Bacteria,4NUZF@976|Bacteroidetes,1IU4P@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4287)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
SRD1_k127_6342472_0	240015.ACP_0487	1.008e-247	800.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6342472_1	1123073.KB899241_gene2917	1.68e-142	469.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,1RQJY@1236|Gammaproteobacteria,1X4RX@135614|Xanthomonadales	135614|Xanthomonadales	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
SRD1_k127_6397789_8	518766.Rmar_2620	2.136e-61	230.0	COG1231@1|root,COG1231@2|Bacteria,4NP86@976|Bacteroidetes	976|Bacteroidetes	E	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRD1_k127_6397789_12	485913.Krac_2611	5.493e-33	134.0	2BHPS@1|root,32BT1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6397789_2	316274.Haur_2324	1.12e-90	315.0	COG2124@1|root,COG2124@2|Bacteria,2G623@200795|Chloroflexi,376IV@32061|Chloroflexia	32061|Chloroflexia	C	PFAM cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRD1_k127_6397789_11	1484460.JSWG01000003_gene756	5.132e-44	170.0	28PQP@1|root,2ZCCM@2|Bacteria,4NSQ2@976|Bacteroidetes,1I5UF@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRD1_k127_6397789_4	234267.Acid_1247	3.441e-69	242.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	pph2	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRD1_k127_6397789_7	1041147.AUFB01000021_gene5256	6.715e-62	223.0	COG2207@1|root,COG2207@2|Bacteria,1REQC@1224|Proteobacteria,2U9DP@28211|Alphaproteobacteria,4BBRX@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
SRD1_k127_6397789_9	1123073.KB899242_gene1301	2.183e-55	204.0	298RU@1|root,3059D@2|Bacteria,1QRA7@1224|Proteobacteria,1TDHB@1236|Gammaproteobacteria,1XAQM@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6397789_0	452637.Oter_4306	1.544e-180	575.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHOR
SRD1_k127_6397789_5	1366050.N234_36240	1.057e-65	231.0	COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria,2VZZR@28216|Betaproteobacteria,1KI9K@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
SRD1_k127_6397789_3	339670.Bamb_3894	1.95e-74	258.0	COG5588@1|root,COG5588@2|Bacteria,1RGIE@1224|Proteobacteria,2VNWW@28216|Betaproteobacteria,1KHHM@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
SRD1_k127_6397789_6	234267.Acid_2472	8.424e-65	235.0	COG0500@1|root,COG2226@2|Bacteria,3Y5WP@57723|Acidobacteria	57723|Acidobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRD1_k127_6397789_1	649747.HMPREF0083_03073	1.741e-92	313.0	COG1024@1|root,COG1024@2|Bacteria,1V0VQ@1239|Firmicutes,4HDR9@91061|Bacilli,274KW@186822|Paenibacillaceae	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD1_k127_6397789_10	324925.Ppha_1753	1.385e-45	180.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6,Hydrolase_4
SRD1_k127_6408951_3	1523503.JPMY01000002_gene3876	2.331e-17	81.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0034214,GO:0042802,GO:0043170,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0061799,GO:0065003,GO:0071704,GO:0071840,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
SRD1_k127_6408951_2	1089553.Tph_c08360	1.757e-39	154.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,42G8D@68295|Thermoanaerobacterales	186801|Clostridia	H	TIGRFAM molybdenum cofactor synthesis domain	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
SRD1_k127_6408951_0	485916.Dtox_3345	4.363e-73	269.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,25ZY5@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
SRD1_k127_6408951_1	309801.trd_1325	6.586e-50	185.0	COG0294@1|root,COG0294@2|Bacteria,2G6A6@200795|Chloroflexi,27XJT@189775|Thermomicrobia	189775|Thermomicrobia	H	Pterin binding enzyme	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRD1_k127_6409508_0	1123242.JH636435_gene2438	1.961e-33	134.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRD1_k127_6413055_1	240015.ACP_0482	5.3e-31	124.0	COG0612@1|root,COG0612@2|Bacteria,3Y3W3@57723|Acidobacteria,2JMK9@204432|Acidobacteriia	204432|Acidobacteriia	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRD1_k127_6413055_3	1006004.GBAG_3243	5.206e-13	82.0	COG2234@1|root,COG2234@2|Bacteria,1P2WI@1224|Proteobacteria,1RRBM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	Catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3	iap	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K09612	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
SRD1_k127_6413055_2	1536775.H70737_12155	4.133e-19	95.0	COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,26R56@186822|Paenibacillaceae	91061|Bacilli	I	phospholipid phosphatase	pgpB3	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRD1_k127_6413055_0	595537.Varpa_2162	1.372e-58	214.0	COG2207@1|root,COG2207@2|Bacteria,1REQC@1224|Proteobacteria,2WEC0@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
SRD1_k127_6438242_1	309801.trd_0207	6.442e-63	231.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,2G7WZ@200795|Chloroflexi,27XSW@189775|Thermomicrobia	189775|Thermomicrobia	L	GIY-YIG type nucleases (URI domain)	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
SRD1_k127_6438242_2	1537994.JQFW01000027_gene2122	9.332e-37	159.0	COG2267@1|root,COG2267@2|Bacteria,1Q6AF@1224|Proteobacteria	1224|Proteobacteria	I	Alpha beta hydrolase	mhpC	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SRD1_k127_6438242_0	489825.LYNGBM3L_51510	6.057e-65	234.0	COG0300@1|root,COG0300@2|Bacteria,1G2JD@1117|Cyanobacteria,1H8N9@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRD1_k127_6443186_0	552811.Dehly_0351	1.416e-144	471.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi,34CVS@301297|Dehalococcoidia	301297|Dehalococcoidia	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
SRD1_k127_6443186_1	1304880.JAGB01000002_gene1828	5.334e-117	400.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRD1_k127_6443186_4	1121929.KB898674_gene3881	0.0004414	48.0	COG4980@1|root,COG4980@2|Bacteria,1VBRG@1239|Firmicutes,4HKZA@91061|Bacilli,470U4@74385|Gracilibacillus	91061|Bacilli	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
SRD1_k127_6443186_2	269800.Tfu_0122	2.701e-33	131.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria,4EJC3@85012|Streptosporangiales	201174|Actinobacteria	T	STAS domain	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRD1_k127_6443186_3	1246626.BleG1_3222	2.04e-11	67.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HFPF@91061|Bacilli,1ZF6G@1386|Bacillus	91061|Bacilli	T	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)	rsbW	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRD1_k127_6467250_1	926549.KI421517_gene1508	2.997e-05	57.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,47K87@768503|Cytophagia	976|Bacteroidetes	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
SRD1_k127_6467250_0	1267535.KB906767_gene2479	4.692e-33	134.0	COG0531@1|root,COG0531@2|Bacteria,3Y2T1@57723|Acidobacteria,2JI3B@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRD1_k127_6488397_4	1125863.JAFN01000001_gene3329	4.338e-46	186.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,43CRY@68525|delta/epsilon subdivisions,2X7ZI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
SRD1_k127_6488397_0	521098.Aaci_1486	8.475e-150	504.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,277Z9@186823|Alicyclobacillaceae	91061|Bacilli	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRD1_k127_6488397_2	264732.Moth_1112	4.852e-91	330.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,42FC8@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRD1_k127_6488397_6	688269.Theth_1656	2.959e-06	59.0	COG1470@1|root,COG1470@2|Bacteria,2GCQ8@200918|Thermotogae	200918|Thermotogae	S	PFAM PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,PEGA
SRD1_k127_6488397_1	1121428.DESHY_60197___1	1.043e-134	447.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,2602V@186807|Peptococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRD1_k127_6488397_5	42256.RradSPS_1898	7.29e-46	181.0	COG0344@1|root,COG0344@2|Bacteria,2IF8Y@201174|Actinobacteria,4CTSY@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRD1_k127_6488397_3	401526.TcarDRAFT_1616	1.717e-66	242.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H2YZ@909932|Negativicutes	909932|Negativicutes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRD1_k127_6489146_2	1121013.P873_01210	2.632e-43	168.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,1X3WV@135614|Xanthomonadales	135614|Xanthomonadales	E	Hydroxymethylglutaryl-CoA lyase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRD1_k127_6489146_0	1382306.JNIM01000001_gene2567	2.684e-190	623.0	COG4770@1|root,COG4770@2|Bacteria,2GBIE@200795|Chloroflexi	200795|Chloroflexi	I	Carbamoyl-phosphate synthetase large chain domain protein	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRD1_k127_6489146_1	1207063.P24_09326	1.026e-54	197.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2TRPS@28211|Alphaproteobacteria,2JQK7@204441|Rhodospirillales	204441|Rhodospirillales	I	Enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD1_k127_649449_7	439481.Aboo_1361	1.3e-18	91.0	COG0346@1|root,arCOG02706@2157|Archaea,2XY0R@28890|Euryarchaeota,3F3CR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRD1_k127_649449_1	1123405.AUMM01000010_gene1224	3.356e-210	667.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,26P9A@186821|Sporolactobacillaceae	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRD1_k127_649449_2	1317118.ATO8_15798	1.614e-143	476.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,4KMA3@93682|Roseivivax	28211|Alphaproteobacteria	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRD1_k127_649449_0	316274.Haur_0944	2.596e-235	740.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi,3750V@32061|Chloroflexia	32061|Chloroflexia	I	PFAM carboxyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRD1_k127_649449_6	1121124.JNIX01000008_gene2450	5.087e-36	154.0	COG0793@1|root,COG0793@2|Bacteria,1PFMH@1224|Proteobacteria,2V89D@28211|Alphaproteobacteria,2KJHZ@204458|Caulobacterales	204458|Caulobacterales	M	Tricorn protease C1 domain	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41,Tricorn_C1
SRD1_k127_649449_5	1157490.EL26_15515	5.509e-60	224.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,279SH@186823|Alicyclobacillaceae	91061|Bacilli	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_9
SRD1_k127_649449_3	525904.Tter_0579	1.427e-137	453.0	COG0801@1|root,COG1469@1|root,COG0801@2|Bacteria,COG1469@2|Bacteria,2NPPF@2323|unclassified Bacteria	2|Bacteria	H	7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK	-	2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25	ko:K00950,ko:K09007,ko:K13940,ko:K17488	ko00790,ko01100,map00790,map01100	M00126,M00841	R00428,R03503,R03504,R04639,R05046,R05048,R10348	RC00002,RC00017,RC00263,RC00294,RC00323,RC00721,RC00943,RC00945,RC01188,RC02504,RC03131	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
SRD1_k127_649449_4	316278.SynRCC307_0788	1.373e-97	325.0	COG0542@1|root,COG0542@2|Bacteria,1G0ZH@1117|Cyanobacteria,1GYXV@1129|Synechococcus	1117|Cyanobacteria	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRD1_k127_6514664_1	260799.BAS3684	5.954e-139	459.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,1ZB7D@1386|Bacillus	91061|Bacilli	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRD1_k127_6514664_0	867903.ThesuDRAFT_00284	3.112e-147	481.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,24971@186801|Clostridia,3WDT5@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
SRD1_k127_6514664_2	309803.CTN_0150	1.409e-60	213.0	COG5405@1|root,COG5405@2|Bacteria,2GCRK@200918|Thermotogae	200918|Thermotogae	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
SRD1_k127_6527910_1	335541.Swol_0160	0.0001172	53.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia	186801|Clostridia	E	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_17
SRD1_k127_6527910_0	1123321.KB905820_gene5558	2.621e-25	113.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_6529554_1	1382304.JNIL01000001_gene245	1.554e-99	335.0	COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,279CW@186823|Alicyclobacillaceae	91061|Bacilli	C	Ferredoxin--NADP reductase	trxB5	-	1.18.1.2,1.19.1.1	ko:K21567	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2
SRD1_k127_6529554_2	439292.Bsel_2450	4.889e-12	73.0	COG2259@1|root,COG2259@2|Bacteria,1V4ER@1239|Firmicutes,4HGZN@91061|Bacilli,26PU6@186821|Sporolactobacillaceae	91061|Bacilli	S	PFAM DoxX family protein	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SRD1_k127_6529554_0	1051632.TPY_1071	2.65e-108	360.0	COG1830@1|root,COG1830@2|Bacteria,1TR4S@1239|Firmicutes,24CYU@186801|Clostridia	186801|Clostridia	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SRD1_k127_6560598_2	644966.Tmar_1081	2.49e-52	192.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,3WCR9@538999|Clostridiales incertae sedis	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRD1_k127_6560598_1	1303518.CCALI_00718	1.079e-83	299.0	COG0157@1|root,COG0157@2|Bacteria	2|Bacteria	H	quinolinate catabolic process	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1988,iHN637.CLJU_RS12010,iLJ478.TM1645	QRPTase_C,QRPTase_N
SRD1_k127_6560598_0	118173.KB235914_gene3743	3.651e-118	397.0	COG0029@1|root,COG0029@2|Bacteria,1G1VD@1117|Cyanobacteria,1H71D@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.nadB,iSbBS512_1146.nadB	FAD_binding_2,Succ_DH_flav_C
SRD1_k127_6578192_0	571166.KI421509_gene2039	9.112e-86	291.0	COG0500@1|root,COG2226@2|Bacteria,1R79J@1224|Proteobacteria,2U421@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRD1_k127_6578192_6	309801.trd_A0044	2.204e-24	111.0	COG4786@1|root,COG4786@2|Bacteria,2GB75@200795|Chloroflexi,27XM0@189775|Thermomicrobia	189775|Thermomicrobia	N	Flagellar basal body rod FlgEFG protein C-terminal	-	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
SRD1_k127_6578192_3	338966.Ppro_3449	3.605e-46	178.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,42N3R@68525|delta/epsilon subdivisions,2WJDN@28221|Deltaproteobacteria,43TGB@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	Flagellar basal body rod FlgEFG protein C-terminal	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
SRD1_k127_6578192_11	1002340.AFCF01000025_gene998	0.0003847	46.0	COG3951@1|root,COG3951@2|Bacteria,1N8ET@1224|Proteobacteria,2UF4I@28211|Alphaproteobacteria,34FYF@302485|Phaeobacter	28211|Alphaproteobacteria	MNO	Rod binding protein	flgJ	-	-	-	-	-	-	-	-	-	-	-	Rod-binding
SRD1_k127_6578192_5	644966.Tmar_1000	2.231e-40	161.0	COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,248M0@186801|Clostridia,3WDBH@538999|Clostridiales incertae sedis	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD1_k127_6578192_2	1121033.AUCF01000014_gene1347	3.926e-50	190.0	COG3685@1|root,COG3685@2|Bacteria,1REKN@1224|Proteobacteria,2U73U@28211|Alphaproteobacteria,2JWRW@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
SRD1_k127_6578192_9	1150599.MPHLEI_01446	2.118e-12	71.0	COG1872@1|root,COG1872@2|Bacteria,2GRF6@201174|Actinobacteria,23B8W@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRD1_k127_6578192_7	37659.JNLN01000001_gene2465	4.874e-18	92.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,24MM3@186801|Clostridia,36FZ8@31979|Clostridiaceae	186801|Clostridia	D	PFAM DivIVA family protein	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
SRD1_k127_6578192_8	871963.Desdi_2790	1.544e-14	79.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,261ZS@186807|Peptococcaceae	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRD1_k127_6578192_4	1458275.AZ34_02215	4.051e-42	163.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,4AAAV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRD1_k127_6578192_1	292415.Tbd_2075	6.747e-51	185.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria,1KSN6@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRD1_k127_6586381_6	1238182.C882_1590	6.799e-35	146.0	COG0438@1|root,COG0438@2|Bacteria,1PVZ8@1224|Proteobacteria,2U8A8@28211|Alphaproteobacteria,2JSXX@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4
SRD1_k127_6586381_2	1173026.Glo7428_0892	8.198e-66	236.0	28IVI@1|root,2Z8TY@2|Bacteria,1G87H@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
SRD1_k127_6586381_5	28072.Nos7524_0336	2.637e-52	195.0	COG2348@1|root,COG2348@2|Bacteria,1GGMU@1117|Cyanobacteria	1117|Cyanobacteria	V	transferase activity, transferring amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6586381_0	29581.BW37_04051	3.91e-114	389.0	COG1657@1|root,COG1657@2|Bacteria,1N9TZ@1224|Proteobacteria,2VX9G@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6586381_3	1202768.JROF01000033_gene2003	1.334e-56	220.0	COG0367@1|root,arCOG00121@2157|Archaea,2XVTD@28890|Euryarchaeota,23TT1@183963|Halobacteria	183963|Halobacteria	E	COG0367 Asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRD1_k127_6586381_4	330214.NIDE2986	6.903e-54	207.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria	2|Bacteria	M	undecaprenyl-phosphate glucose phosphotransferase activity	wcaJ	-	-	ko:K03606,ko:K20997	ko02025,ko05111,map02025,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
SRD1_k127_6586381_1	396588.Tgr7_2388	4.197e-82	301.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RREJ@1236|Gammaproteobacteria,1WWEV@135613|Chromatiales	135613|Chromatiales	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
SRD1_k127_6587158_0	1382359.JIAL01000001_gene1643	2.412e-220	702.0	COG0841@1|root,COG0841@2|Bacteria,3Y2TW@57723|Acidobacteria,2JIKU@204432|Acidobacteriia	204432|Acidobacteriia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRD1_k127_6590145_3	518766.Rmar_2016	2.243e-12	70.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	nosY	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
SRD1_k127_6590145_1	479434.Sthe_0737	2.441e-146	492.0	COG1131@1|root,COG3420@1|root,COG1131@2|Bacteria,COG3420@2|Bacteria,2G7PN@200795|Chloroflexi,27Z0E@189775|Thermomicrobia	189775|Thermomicrobia	P	Domain present in carbohydrate binding proteins and sugar hydrolses	-	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	ABC_tran,NosD
SRD1_k127_6590145_2	479434.Sthe_0736	2.602e-44	177.0	COG4314@1|root,COG4314@2|Bacteria,2G8NV@200795|Chloroflexi,27Z7G@189775|Thermomicrobia	189775|Thermomicrobia	C	lipoprotein involved in nitrous oxide reduction	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6590145_0	479434.Sthe_0735	1.245e-241	765.0	COG4263@1|root,COG4263@2|Bacteria,2G8B2@200795|Chloroflexi,27YVK@189775|Thermomicrobia	189775|Thermomicrobia	C	nitrous-oxide reductase activity	-	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRD1_k127_6602432_0	525904.Tter_0931	7.327e-109	365.0	COG0343@1|root,COG0343@2|Bacteria,2NNQS@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475	TGT
SRD1_k127_6602432_1	1089548.KI783301_gene1157	1.009e-75	275.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,3WE09@539002|Bacillales incertae sedis	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRD1_k127_6602432_4	309801.trd_1033	3.65e-25	120.0	COG0597@1|root,COG0597@2|Bacteria,2G740@200795|Chloroflexi,27YJK@189775|Thermomicrobia	189775|Thermomicrobia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRD1_k127_6602432_3	1122218.KB893654_gene1893	2.486e-42	165.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria,1JVP8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Cytochrome C biogenesis protein transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRD1_k127_6602432_2	1162668.LFE_1068	5.576e-60	218.0	COG0682@1|root,COG0682@2|Bacteria,3J0G4@40117|Nitrospirae	40117|Nitrospirae	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRD1_k127_6620058_0	661478.OP10G_0771	3.764e-135	459.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRD1_k127_6664326_3	1382356.JQMP01000004_gene332	5.785e-80	273.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi,27XVS@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRD1_k127_6664326_6	525904.Tter_1715	7.319e-53	192.0	COG2110@1|root,COG2110@2|Bacteria,2NPPR@2323|unclassified Bacteria	2|Bacteria	S	Appr-1'-p processing enzyme	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
SRD1_k127_6664326_0	452637.Oter_1134	1.834e-121	397.0	COG2084@1|root,COG2084@2|Bacteria,46S95@74201|Verrucomicrobia,3K74D@414999|Opitutae	414999|Opitutae	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
SRD1_k127_6664326_10	1162668.LFE_2299	1.036e-46	173.0	2DHFW@1|root,2ZZKM@2|Bacteria	2|Bacteria	-	-	phyH	-	-	-	-	-	-	-	-	-	-	-	DUF5069
SRD1_k127_6664326_13	1121946.AUAX01000009_gene4347	1.418e-13	81.0	COG2267@1|root,COG2267@2|Bacteria,2HUEM@201174|Actinobacteria,4DEP2@85008|Micromonosporales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRD1_k127_6664326_4	1382359.JIAL01000001_gene2536	5.207e-78	271.0	COG4301@1|root,COG4301@2|Bacteria,3Y2JF@57723|Acidobacteria,2JIA5@204432|Acidobacteriia	204432|Acidobacteriia	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
SRD1_k127_6664326_12	595536.ADVE02000001_gene1705	5.158e-36	152.0	COG3386@1|root,COG3386@2|Bacteria,1N3BV@1224|Proteobacteria	1224|Proteobacteria	G	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1
SRD1_k127_6664326_15	671143.DAMO_1987	1.243e-06	56.0	COG2259@1|root,COG2259@2|Bacteria,2NQ4C@2323|unclassified Bacteria	2|Bacteria	S	DoxX	ndh	-	1.6.99.3,1.8.5.2	ko:K03885,ko:K16937	ko00190,ko00920,ko01120,map00190,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxD,DoxX,Pyr_redox_2
SRD1_k127_6664326_14	1034943.BN1094_00880	2.755e-07	59.0	2AIZV@1|root,319HX@2|Bacteria,1Q2TZ@1224|Proteobacteria,1T78E@1236|Gammaproteobacteria,1JF1N@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6664326_7	383372.Rcas_2531	5.612e-51	194.0	COG1174@1|root,COG1174@2|Bacteria,2G8XF@200795|Chloroflexi,375PS@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRD1_k127_6664326_1	321327.CYA_2231	3.726e-100	338.0	COG1125@1|root,COG1125@2|Bacteria,1G21Q@1117|Cyanobacteria,1H46T@1129|Synechococcus	1117|Cyanobacteria	P	Quaternary amine uptake ABC transporter (QAT) family, ATP-binding protein	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
SRD1_k127_6664326_2	1229172.JQFA01000002_gene3587	5.799e-91	308.0	COG1732@1|root,COG1732@2|Bacteria,1G1ZS@1117|Cyanobacteria,1H9PY@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SRD1_k127_6664326_9	1173264.KI913949_gene476	1.015e-48	181.0	COG1174@1|root,COG1174@2|Bacteria,1G5C0@1117|Cyanobacteria,1H8EE@1150|Oscillatoriales	1117|Cyanobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRD1_k127_6664326_11	1306406.ASHX01000002_gene4543	9.792e-37	149.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
SRD1_k127_6664326_5	292459.STH2398	4.057e-62	240.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
SRD1_k127_6664326_8	1157490.EL26_16960	5.361e-50	189.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,4HAY4@91061|Bacilli,2785U@186823|Alicyclobacillaceae	91061|Bacilli	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
SRD1_k127_6694040_1	555088.DealDRAFT_2676	4.422e-120	410.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,42JRU@68298|Syntrophomonadaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SRD1_k127_6694040_2	518766.Rmar_1034	7.592e-117	394.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1FINY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRD1_k127_6694040_5	562970.Btus_0102	4.876e-68	241.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,277Z5@186823|Alicyclobacillaceae	91061|Bacilli	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
SRD1_k127_6694040_8	292459.STH1866	9.344e-41	156.0	COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,24JBK@186801|Clostridia	186801|Clostridia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRD1_k127_6694040_10	586416.GZ22_00505	1.737e-25	108.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli	91061|Bacilli	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRD1_k127_6694040_13	2074.JNYD01000001_gene6278	8.218e-05	50.0	COG0443@1|root,COG3391@1|root,COG0443@2|Bacteria,COG3391@2|Bacteria,2GNTE@201174|Actinobacteria,4E043@85010|Pseudonocardiales	201174|Actinobacteria	O	Hsp70 protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
SRD1_k127_6694040_6	1267005.KB911256_gene1853	8.665e-50	185.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria,3N8E7@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRD1_k127_6694040_9	661478.OP10G_0325	2.963e-36	140.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2,YCII
SRD1_k127_6694040_0	861299.J421_0643	1.136e-148	486.0	COG4941@1|root,COG4941@2|Bacteria,1ZUFS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_6694040_11	1282876.BAOK01000002_gene345	2.042e-17	89.0	COG2818@1|root,COG2818@2|Bacteria,1R3WB@1224|Proteobacteria,2TTR8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	3-methyladenine DNA glycosylase	MA20_23545	-	-	-	-	-	-	-	-	-	-	-	Adenine_glyco
SRD1_k127_6694040_7	861299.J421_4352	1.308e-47	183.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	yecE	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRD1_k127_6694040_12	661478.OP10G_1202	2.859e-12	79.0	COG0103@1|root,COG0103@2|Bacteria	2|Bacteria	J	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
SRD1_k127_6694040_3	1120999.JONM01000002_gene806	2.278e-94	331.0	2F0HD@1|root,33TK6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6694040_4	1242864.D187_008565	6.331e-90	302.0	COG3967@1|root,COG3967@2|Bacteria,1QSYJ@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K14189	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
SRD1_k127_670292_2	926569.ANT_04550	2.153e-40	158.0	COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM glutamine amidotransferase class-I	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRD1_k127_670292_1	138119.DSY1577	5.956e-68	238.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,2612Y@186807|Peptococcaceae	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRD1_k127_670292_6	888727.HMPREF9092_0080	3.484e-06	53.0	COG1388@1|root,COG1388@2|Bacteria,1VK5T@1239|Firmicutes,24UT1@186801|Clostridia	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRD1_k127_670292_3	1415775.U729_2782	3.521e-31	124.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,36KHC@31979|Clostridiaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRD1_k127_670292_0	498761.HM1_2322	7.965e-256	807.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRD1_k127_670292_4	879310.HMPREF9162_1040	4.691e-21	107.0	COG1538@1|root,COG1538@2|Bacteria,1TRDS@1239|Firmicutes,4H2S7@909932|Negativicutes	909932|Negativicutes	MU	outer membrane efflux protein	tolC	-	-	-	-	-	-	-	-	-	-	-	OEP
SRD1_k127_670292_5	383372.Rcas_1117	7.808e-12	70.0	COG1366@1|root,COG1366@2|Bacteria,2GAZW@200795|Chloroflexi,377MW@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS
SRD1_k127_6703801_1	29581.BW37_04051	1.32e-112	373.0	COG1657@1|root,COG1657@2|Bacteria,1N9TZ@1224|Proteobacteria,2VX9G@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6703801_2	234267.Acid_6257	1.886e-81	295.0	COG1520@1|root,COG4934@1|root,COG1520@2|Bacteria,COG4934@2|Bacteria,3Y99I@57723|Acidobacteria	57723|Acidobacteria	O	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Lectin_legB
SRD1_k127_6703801_4	1354722.JQLS01000008_gene2891	2.772e-60	220.0	COG1235@1|root,COG1235@2|Bacteria,1MWI5@1224|Proteobacteria,2TQX4@28211|Alphaproteobacteria,46PH4@74030|Roseovarius	28211|Alphaproteobacteria	S	May be involved in the transport of PQQ or its precursor to the periplasm	pqqB	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
SRD1_k127_6703801_3	405948.SACE_4446	1.268e-80	274.0	COG5424@1|root,COG5424@2|Bacteria,2I9SS@201174|Actinobacteria,4E05W@85010|Pseudonocardiales	201174|Actinobacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	pqqC	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	TENA_THI-4
SRD1_k127_6703801_5	426117.M446_5767	2.568e-06	59.0	COG0535@1|root,COG0535@2|Bacteria,1N7TR@1224|Proteobacteria,2UFAS@28211|Alphaproteobacteria,1JXZU@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM coenzyme PQQ synthesis D	pqqD	-	-	ko:K06138	-	-	-	-	ko00000	-	-	-	PqqD
SRD1_k127_6703801_0	349163.Acry_0081	6.413e-118	390.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2TTS5@28211|Alphaproteobacteria,2JR0C@204441|Rhodospirillales	204441|Rhodospirillales	S	peptidyl-tyrosine modification	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SRD1_k127_6716968_1	292459.STH163	3.792e-17	87.0	COG4632@1|root,COG4632@2|Bacteria,1TQBV@1239|Firmicutes,24AWX@186801|Clostridia	186801|Clostridia	G	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,Metallophos,NAGPA,Pur_ac_phosph_N,SLH
SRD1_k127_6716968_2	867845.KI911784_gene2459	1.509e-08	65.0	COG3012@1|root,COG3012@2|Bacteria,2GACR@200795|Chloroflexi,375EK@32061|Chloroflexia	32061|Chloroflexia	S	PFAM SEC-C motif domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
SRD1_k127_6716968_0	1123023.JIAI01000001_gene6759	1.989e-110	377.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria	201174|Actinobacteria	E	gamma-glutamyltransferase	ywrD	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRD1_k127_6736288_1	66377.JOBH01000010_gene6394	1.326e-05	55.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRD1_k127_6736288_0	2074.JNYD01000046_gene7295	5.518e-60	228.0	COG0642@1|root,COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,2GKN8@201174|Actinobacteria,4DZ1T@85010|Pseudonocardiales	201174|Actinobacteria	KT	Serine phosphatase RsbU, regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,SpoIIE
SRD1_k127_6786290_4	1123248.KB893359_gene2149	6.872e-14	76.0	COG3511@1|root,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	phoC	GO:0003674,GO:0003824,GO:0003993,GO:0004438,GO:0004805,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006139,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006742,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009109,GO:0009117,GO:0009166,GO:0009987,GO:0016310,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019203,GO:0019362,GO:0019364,GO:0019438,GO:0019439,GO:0019637,GO:0030258,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046486,GO:0046488,GO:0046496,GO:0046700,GO:0046834,GO:0046854,GO:0050189,GO:0050192,GO:0051186,GO:0051187,GO:0052744,GO:0052866,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072526,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.3.64	ko:K21302	ko00562,ko01100,ko05152,map00562,map01100,map05152	-	-	-	ko00000,ko00001,ko01000	-	-	-	He_PIG,Phosphoesterase
SRD1_k127_6786290_3	1009370.ALO_08028	1.044e-32	129.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4H4PT@909932|Negativicutes	909932|Negativicutes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRD1_k127_6786290_0	477974.Daud_1873	1.811e-113	379.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,25ZZB@186807|Peptococcaceae	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRD1_k127_6786290_2	292459.STH434	8.299e-38	153.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRD1_k127_6786290_1	477974.Daud_1204	5.175e-104	353.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,26035@186807|Peptococcaceae	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18870	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRD1_k127_6790515_2	981369.JQMJ01000004_gene2951	4.28e-50	183.0	COG0428@1|root,COG0428@2|Bacteria,2IBHZ@201174|Actinobacteria,2NHVS@228398|Streptacidiphilus	201174|Actinobacteria	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRD1_k127_6790515_0	1313172.YM304_35460	8.214e-273	863.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4CMRX@84992|Acidimicrobiia	84992|Acidimicrobiia	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRD1_k127_6790515_3	670487.Ocepr_0214	7.418e-39	156.0	COG1028@1|root,COG1028@2|Bacteria,1WNI0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD1_k127_6790515_1	479434.Sthe_2317	2.836e-127	423.0	COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi,27YVX@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
SRD1_k127_6790515_4	591001.Acfer_1638	1.334e-32	145.0	COG4783@1|root,COG4783@2|Bacteria,1TVZ0@1239|Firmicutes,4H2D5@909932|Negativicutes	909932|Negativicutes	M	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRD1_k127_6799150_1	420246.GTNG_1035	3.54e-48	181.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,1WEXF@129337|Geobacillus	91061|Bacilli	S	Dak1_2	yloV	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRD1_k127_6799150_3	1382304.JNIL01000001_gene667	9.435e-19	88.0	COG0227@1|root,COG0227@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRD1_k127_6799150_0	309801.trd_0172	5.7e-53	205.0	COG0611@1|root,COG0611@2|Bacteria,2G6SH@200795|Chloroflexi,27XMF@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRD1_k127_6799150_2	525904.Tter_0287	5.607e-41	154.0	COG0036@1|root,COG0036@2|Bacteria,2NP9N@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1386,iLJ478.TM1718	Ribul_P_3_epim
SRD1_k127_6819846_6	575540.Isop_1916	3.037e-15	89.0	COG1999@1|root,COG2322@1|root,COG1999@2|Bacteria,COG2322@2|Bacteria,2IZH2@203682|Planctomycetes	203682|Planctomycetes	S	SCO1/SenC	-	-	-	ko:K07152,ko:K08976	-	-	-	-	ko00000,ko03029	-	-	-	DUF420,SCO1-SenC
SRD1_k127_6819846_8	1382303.JPOM01000001_gene612	2.83e-05	51.0	COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,2U2QG@28211|Alphaproteobacteria,2KK9R@204458|Caulobacterales	204458|Caulobacterales	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
SRD1_k127_6819846_4	1117379.BABA_16067	1.077e-57	213.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,4HCSI@91061|Bacilli,1ZDR0@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRD1_k127_6819846_1	891968.Anamo_1556	1.475e-101	352.0	COG1052@1|root,COG1052@2|Bacteria,3TARR@508458|Synergistetes	508458|Synergistetes	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRD1_k127_6819846_2	644966.Tmar_0895	2.208e-97	331.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRD1_k127_6819846_0	635013.TherJR_2718	4.388e-127	421.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,248G0@186801|Clostridia,25ZYM@186807|Peptococcaceae	186801|Clostridia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRD1_k127_6819846_3	1209989.TepiRe1_0763	8.985e-85	290.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,42EYZ@68295|Thermoanaerobacterales	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRD1_k127_6819846_5	479434.Sthe_2932	4.566e-16	86.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi,27YIV@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRD1_k127_6825280_3	1123386.AUIW01000002_gene1257	1.341e-33	136.0	2E6PD@1|root,3319R@2|Bacteria,1WKCJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6825280_4	1123386.AUIW01000002_gene1257	7.701e-31	128.0	2E6PD@1|root,3319R@2|Bacteria,1WKCJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6825280_0	350688.Clos_0278	4.572e-123	414.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,248KF@186801|Clostridia,36F3M@31979|Clostridiaceae	186801|Clostridia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRD1_k127_6825280_1	684949.ATTJ01000001_gene3018	2.715e-90	311.0	COG0150@1|root,COG0150@2|Bacteria,1WIP0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	PFAM AIR synthase related protein, N-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRD1_k127_6825280_2	1961.JOAK01000003_gene1527	9.125e-44	178.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF11
SRD1_k127_6862733_3	926554.KI912674_gene2621	1.904e-45	184.0	COG1878@1|root,COG1878@2|Bacteria,1WJ7A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRD1_k127_6862733_2	284031.JNXD01000025_gene389	6.465e-62	230.0	COG1082@1|root,COG1082@2|Bacteria,2IEA7@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRD1_k127_6862733_1	1382306.JNIM01000001_gene735	6.165e-80	276.0	COG1028@1|root,COG1028@2|Bacteria	1382306.JNIM01000001_gene735|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6862733_0	525904.Tter_2125	5.642e-151	490.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2NQGX@2323|unclassified Bacteria	2|Bacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SRD1_k127_6867729_2	765420.OSCT_1804	6.879e-40	166.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD1_k127_6867729_3	1304874.JAFY01000007_gene1861	1.55e-23	118.0	COG3203@1|root,COG3203@2|Bacteria,3TA5G@508458|Synergistetes	508458|Synergistetes	M	PFAM S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
SRD1_k127_6867729_4	626939.HMPREF9443_00615	5.903e-19	100.0	COG0816@1|root,COG0816@2|Bacteria,1V9WY@1239|Firmicutes,4H57J@909932|Negativicutes	909932|Negativicutes	L	Likely ribonuclease with RNase H fold.	-	-	-	-	-	-	-	-	-	-	-	-	RuvX,Tex_YqgF
SRD1_k127_6867729_5	742743.HMPREF9453_01968	5.066e-15	87.0	COG4372@1|root,COG4372@2|Bacteria,1TRKA@1239|Firmicutes,4H36C@909932|Negativicutes	909932|Negativicutes	S	Protein of unknown function (DUF3084)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3084
SRD1_k127_6867729_1	401526.TcarDRAFT_1335	1.335e-61	233.0	COG0795@1|root,COG0795@2|Bacteria,1TRZG@1239|Firmicutes,4H2PV@909932|Negativicutes	909932|Negativicutes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
SRD1_k127_6867729_0	445970.ALIPUT_00067	1.55e-85	289.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,2FKZE@200643|Bacteroidia,22U72@171550|Rikenellaceae	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
SRD1_k127_6867729_7	316274.Haur_4434	0.0002029	53.0	COG3307@1|root,COG3307@2|Bacteria,2G6TE@200795|Chloroflexi,375HE@32061|Chloroflexia	32061|Chloroflexia	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRD1_k127_6867729_6	592015.HMPREF1705_01450	1.469e-06	53.0	COG1663@1|root,COG4370@1|root,COG1663@2|Bacteria,COG4370@2|Bacteria,3T9ZA@508458|Synergistetes	508458|Synergistetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
SRD1_k127_6886265_1	1185876.BN8_00122	9.352e-06	59.0	COG1629@1|root,COG4771@2|Bacteria,4NH5I@976|Bacteroidetes,47KFR@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRD1_k127_6886265_0	1382306.JNIM01000001_gene138	1.772e-39	149.0	COG0693@1|root,COG0693@2|Bacteria,2G6I3@200795|Chloroflexi	200795|Chloroflexi	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRD1_k127_6900380_0	1382306.JNIM01000001_gene1447	5.487e-172	548.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRD1_k127_6900380_1	1382306.JNIM01000001_gene1448	5.518e-152	497.0	COG1020@1|root,COG1020@2|Bacteria,2G86H@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding
SRD1_k127_6923411_0	635013.TherJR_1754	5.854e-162	528.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,2603X@186807|Peptococcaceae	186801|Clostridia	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
SRD1_k127_6923411_2	1122614.JHZF01000013_gene3440	0.000198	53.0	COG1934@1|root,COG1934@2|Bacteria,1MXGA@1224|Proteobacteria,2U6DD@28211|Alphaproteobacteria,2PEC3@252301|Oceanicola	28211|Alphaproteobacteria	S	OstA-like protein	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
SRD1_k127_6923411_1	1265502.KB905959_gene266	3.091e-35	146.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,4A9TY@80864|Comamonadaceae	28216|Betaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	rimN	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
SRD1_k127_6948888_4	546271.Selsp_1082	1.21e-06	59.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H2Z9@909932|Negativicutes	909932|Negativicutes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SRD1_k127_6948888_1	1089553.Tph_c08980	3.246e-149	508.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,42F1D@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRD1_k127_6948888_0	760568.Desku_1682	1.24e-164	531.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,2613E@186807|Peptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRD1_k127_6948888_3	1379698.RBG1_1C00001G0539	3.973e-21	95.0	COG0721@1|root,COG0721@2|Bacteria,2NPXC@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	iAF987.Gmet_0076	Glu-tRNAGln
SRD1_k127_6948888_2	997346.HMPREF9374_2052	3.656e-80	286.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,27BPG@186824|Thermoactinomycetaceae	91061|Bacilli	J	tRNA (Uracil-5-)-methyltransferase	rumA	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SRD1_k127_6955370_1	1410618.JNKI01000012_gene630	1.47e-38	160.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,4H3ET@909932|Negativicutes	909932|Negativicutes	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
SRD1_k127_6955370_0	1121430.JMLG01000002_gene1040	2.098e-46	187.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,249MB@186801|Clostridia,260BT@186807|Peptococcaceae	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRD1_k127_6955370_2	521011.Mpal_0753	1.003e-11	68.0	COG0671@1|root,arCOG07501@2157|Archaea,2XYXG@28890|Euryarchaeota	28890|Euryarchaeota	I	PFAM phosphatidate cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6956198_8	237368.SCABRO_01997	1.406e-73	277.0	COG1007@1|root,COG1007@2|Bacteria,2IXC6@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRD1_k127_6956198_7	243231.GSU0350	9.46e-87	305.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRD1_k127_6956198_2	929556.Solca_3729	7.575e-139	465.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRD1_k127_6956198_15	1382306.JNIM01000001_gene3462	1.739e-20	102.0	COG0713@1|root,COG0713@2|Bacteria,2G6TP@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRD1_k127_6956198_16	667014.Thein_1631	4.059e-15	83.0	COG0839@1|root,COG0839@2|Bacteria,2GHWH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRD1_k127_6956198_10	292459.STH1594	3.393e-55	200.0	COG1143@1|root,COG1143@2|Bacteria,1VBXF@1239|Firmicutes,24MWM@186801|Clostridia	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRD1_k127_6956198_6	1051632.TPY_0864	4.033e-95	333.0	COG1005@1|root,COG1005@2|Bacteria,1TQNU@1239|Firmicutes,25E6Z@186801|Clostridia,3WDJU@538999|Clostridiales incertae sedis	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRD1_k127_6956198_0	292459.STH1592	4.712e-187	629.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia	186801|Clostridia	C	Molybdopterin oxidoreductase, Fe4S4	-	-	1.17.1.10,1.6.5.3	ko:K00336,ko:K05299	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRD1_k127_6956198_1	1051632.TPY_0862	3.877e-155	501.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3WCEN@538999|Clostridiales incertae sedis	186801|Clostridia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	hymB	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
SRD1_k127_6956198_12	1313172.YM304_04100	1.954e-34	139.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4CN1U@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRD1_k127_6956198_3	1128421.JAGA01000002_gene140	3.304e-134	444.0	COG0649@1|root,COG0649@2|Bacteria,2NNWG@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa,NiFeSe_Hases
SRD1_k127_6956198_13	926566.Terro_1579	1.128e-30	130.0	COG0852@1|root,COG0852@2|Bacteria,3Y4IQ@57723|Acidobacteria,2JJCT@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRD1_k127_6956198_9	1340493.JNIF01000003_gene3241	6.925e-58	212.0	COG0377@1|root,COG0377@2|Bacteria,3Y475@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRD1_k127_6956198_11	292459.STH1586	2.07e-39	149.0	COG0838@1|root,COG0838@2|Bacteria,1V6P3@1239|Firmicutes,24MPD@186801|Clostridia	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRD1_k127_6956198_5	82654.Pse7367_1774	1.078e-112	384.0	COG0031@1|root,COG0031@2|Bacteria,1G0T4@1117|Cyanobacteria,1H7K5@1150|Oscillatoriales	1117|Cyanobacteria	E	Cysteine synthase	cysM	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD1_k127_6956198_14	401053.AciPR4_4156	1.05e-24	114.0	COG2020@1|root,COG2020@2|Bacteria,3Y53B@57723|Acidobacteria,2JJHM@204432|Acidobacteriia	204432|Acidobacteriia	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRD1_k127_6956198_4	525904.Tter_1226	1.943e-125	413.0	COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2
SRD1_k127_6956198_17	869209.Tresu_0849	3.681e-10	73.0	COG0457@1|root,COG0457@2|Bacteria,2J58Z@203691|Spirochaetes	203691|Spirochaetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_7,TPR_8
SRD1_k127_6998134_0	1134445.AJJM01000031_gene1407	1.577e-37	160.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria	201174|Actinobacteria	L	DNA helicase	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRD1_k127_7024623_1	215803.DB30_5754	3.864e-92	309.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,42QYJ@68525|delta/epsilon subdivisions,2WN82@28221|Deltaproteobacteria,2YX3U@29|Myxococcales	28221|Deltaproteobacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRD1_k127_7024623_0	1382356.JQMP01000003_gene1523	2.645e-200	636.0	COG0174@1|root,COG0174@2|Bacteria,2G61M@200795|Chloroflexi,27YTI@189775|Thermomicrobia	189775|Thermomicrobia	E	Glutamine synthetase, beta-Grasp domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRD1_k127_7024623_2	1223523.H340_01554	1.138e-36	149.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the FPG family	mutM1	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRD1_k127_7024623_5	118168.MC7420_6649	4.349e-18	97.0	COG0457@1|root,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1H968@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRD1_k127_7024623_3	861299.J421_3195	7.587e-31	125.0	COG0251@1|root,COG0251@2|Bacteria,1ZTSF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRD1_k127_7024623_6	767817.Desgi_1807	1.271e-07	55.0	COG0695@1|root,COG0695@2|Bacteria,1UUC1@1239|Firmicutes,2569X@186801|Clostridia,266AY@186807|Peptococcaceae	186801|Clostridia	O	Glutaredoxin	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
SRD1_k127_7024623_4	316274.Haur_4216	3.881e-18	99.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G8CK@200795|Chloroflexi,3776C@32061|Chloroflexia	32061|Chloroflexia	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
SRD1_k127_7071007_15	1380390.JIAT01000010_gene3985	3.862e-13	74.0	COG0711@1|root,COG0711@2|Bacteria,2HP0U@201174|Actinobacteria,4CQAI@84995|Rubrobacteria	84995|Rubrobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7071007_12	1410632.JHWW01000001_gene1035	2.857e-26	122.0	COG1835@1|root,COG1835@2|Bacteria,1UZQR@1239|Firmicutes	1239|Firmicutes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRD1_k127_7071007_13	1125971.ASJB01000042_gene3466	8.535e-20	100.0	COG2755@1|root,COG2755@2|Bacteria,2GP5V@201174|Actinobacteria,4DYK2@85010|Pseudonocardiales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,RicinB_lectin_2
SRD1_k127_7071007_3	1384049.CD29_01030	2.613e-58	218.0	COG3340@1|root,COG3340@2|Bacteria,1TRBA@1239|Firmicutes,4HB19@91061|Bacilli,3IVT6@400634|Lysinibacillus	91061|Bacilli	E	Belongs to the peptidase S51 family	ygaJ	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRD1_k127_7071007_4	326427.Cagg_2052	1.719e-57	216.0	COG1893@1|root,COG1893@2|Bacteria,2G718@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRD1_k127_7071007_5	258594.RPA0080	1.659e-56	201.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,3JYQC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRD1_k127_7071007_7	867903.ThesuDRAFT_02241	4.326e-47	173.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3WCHY@538999|Clostridiales incertae sedis	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRD1_k127_7071007_14	1459636.NTE_03059	9.72e-17	81.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7071007_9	479437.Elen_1751	1.278e-29	128.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
SRD1_k127_7071007_2	1121468.AUBR01000036_gene1295	1.614e-60	228.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,42FQZ@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRD1_k127_7071007_10	1321814.HMPREF9089_00792	8.83e-28	123.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,25WC9@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
SRD1_k127_7071007_0	555079.Toce_2184	8.658e-134	445.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,42ERB@68295|Thermoanaerobacterales	186801|Clostridia	J	TIGRFAM Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRD1_k127_7071007_11	649638.Trad_1150	4.503e-27	126.0	COG0628@1|root,COG0628@2|Bacteria,1WIXU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG0628 permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRD1_k127_7071007_16	1121861.KB899915_gene1929	0.0001326	51.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2UF5C@28211|Alphaproteobacteria,2JTU6@204441|Rhodospirillales	204441|Rhodospirillales	K	FR47-like protein	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRD1_k127_7071007_8	103733.JNYO01000007_gene5143	1.208e-33	144.0	COG2199@1|root,COG3437@1|root,COG3437@2|Bacteria,COG3706@2|Bacteria,2I49F@201174|Actinobacteria,4E0HG@85010|Pseudonocardiales	201174|Actinobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5
SRD1_k127_7071007_1	696281.Desru_2418	3.065e-63	227.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,24BQA@186801|Clostridia,2601C@186807|Peptococcaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SRD1_k127_7071007_6	1449063.JMLS01000012_gene5434	2.375e-51	197.0	COG0501@1|root,COG0501@2|Bacteria,1TRQE@1239|Firmicutes,4HD5G@91061|Bacilli,26VWH@186822|Paenibacillaceae	91061|Bacilli	O	CAAX prenyl protease N-terminal, five membrane helices	yhfN	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M48_N
SRD1_k127_7071007_17	342610.Patl_3818	0.0005089	52.0	COG1629@1|root,COG1629@2|Bacteria,1MWTT@1224|Proteobacteria,1RRQ9@1236|Gammaproteobacteria,2Q1DI@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	OMP_b-brl_3,Plug,TonB_dep_Rec
SRD1_k127_7084558_3	1142394.PSMK_08090	3.026e-19	87.0	COG1249@1|root,COG1249@2|Bacteria,2IX5H@203682|Planctomycetes	203682|Planctomycetes	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRD1_k127_7084558_1	869210.Marky_0708	7.968e-117	392.0	COG0508@1|root,COG0508@2|Bacteria,1WI0W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRD1_k127_7084558_0	290397.Adeh_1826	6.937e-123	405.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42N06@68525|delta/epsilon subdivisions,2WK5N@28221|Deltaproteobacteria,2YTX4@29|Myxococcales	28221|Deltaproteobacteria	C	Transketolase, pyrimidine binding domain	bkdB	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K00167	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRD1_k127_7084558_2	867903.ThesuDRAFT_01196	7.533e-95	322.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,249HX@186801|Clostridia	186801|Clostridia	C	dehydrogenase, E1 component	-	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRD1_k127_7091147_0	1472716.KBK24_0111600	8.804e-96	323.0	COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria,2VK7I@28216|Betaproteobacteria,1K561@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRD1_k127_7091147_1	309801.trd_A0739	1.338e-22	107.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,27YHJ@189775|Thermomicrobia	189775|Thermomicrobia	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRD1_k127_7091147_2	1156919.QWC_07039	1.221e-12	72.0	COG1225@1|root,COG1225@2|Bacteria,1RHSM@1224|Proteobacteria,2VQNM@28216|Betaproteobacteria,3T3UH@506|Alcaligenaceae	28216|Betaproteobacteria	O	Peroxiredoxin	bcp_2	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
SRD1_k127_7115723_2	360911.EAT1b_2077	6.716e-07	54.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HFPF@91061|Bacilli	91061|Bacilli	T	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)	rsbW	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRD1_k127_7115723_1	936550.HMPREF1492_1105	2.417e-74	258.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4CUM2@84998|Coriobacteriia	84998|Coriobacteriia	K	RNA polymerase sigma-70 factor, sigma-B F G subfamily	-	-	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD1_k127_7115723_0	396588.Tgr7_1289	2.69e-198	645.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1WXPB@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRD1_k127_712769_1	1173020.Cha6605_0967	5.733e-79	272.0	arCOG10456@1|root,2ZA6T@2|Bacteria,1G36D@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_712769_8	891968.Anamo_1515	1.036e-24	109.0	29A4E@1|root,2ZX5H@2|Bacteria,3TB5P@508458|Synergistetes	508458|Synergistetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_712769_0	292459.STH1564	9.044e-175	571.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia	186801|Clostridia	H	Belongs to the UbiD family	-	-	4.1.1.61,4.1.1.98	ko:K03182,ko:K16239	ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120	M00117	R01238,R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRD1_k127_712769_3	709986.Deima_0590	4.125e-68	242.0	COG0382@1|root,COG0382@2|Bacteria,1WI4B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	COGs COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRD1_k127_712769_7	420324.KI911996_gene7844	2.649e-31	139.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2TT0T@28211|Alphaproteobacteria,1JQTG@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	PFAM Extracellular ligand-binding receptor	livK	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRD1_k127_712769_10	642492.Clole_0385	5.779e-07	57.0	COG2227@1|root,COG2227@2|Bacteria,1UXZZ@1239|Firmicutes,24BIT@186801|Clostridia	186801|Clostridia	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRD1_k127_712769_9	368407.Memar_0655	4.633e-10	66.0	COG0500@1|root,arCOG01791@2157|Archaea,2XZTQ@28890|Euryarchaeota,2NAGP@224756|Methanomicrobia	224756|Methanomicrobia	Q	Methyltransferase domain	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25
SRD1_k127_712769_6	1444309.JAQG01000075_gene141	2.834e-37	150.0	COG1587@1|root,COG1587@2|Bacteria,1UHSJ@1239|Firmicutes,4ITCT@91061|Bacilli,277CB@186822|Paenibacillaceae	91061|Bacilli	H	Uroporphyrinogen-III synthase HemD	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
SRD1_k127_712769_2	717605.Theco_2575	8.328e-74	277.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,4HAVC@91061|Bacilli,26RDF@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08420	GlutR_N,GlutR_dimer,Shikimate_DH
SRD1_k127_712769_5	1123320.KB889585_gene1858	4.343e-43	171.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria	201174|Actinobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRD1_k127_712769_4	264732.Moth_1244	3.32e-53	192.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,42EMC@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_7134412_3	1203606.HMPREF1526_02718	2.754e-17	96.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,36DGZ@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRD1_k127_7134412_2	273068.TTE0957	5.563e-35	145.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,42FBX@68295|Thermoanaerobacterales	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRD1_k127_7134412_0	401526.TcarDRAFT_1254	8.423e-118	389.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H28A@909932|Negativicutes	909932|Negativicutes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRD1_k127_7134412_1	370438.PTH_0875	9.893e-60	218.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,260NG@186807|Peptococcaceae	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
SRD1_k127_7143415_1	1121468.AUBR01000005_gene56	3.129e-49	186.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,42FHI@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM Aluminium resistance family protein	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
SRD1_k127_7143415_0	555079.Toce_0339	1.766e-54	209.0	COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,24808@186801|Clostridia,42FMW@68295|Thermoanaerobacterales	186801|Clostridia	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	-	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
SRD1_k127_7163930_6	1123075.AUDP01000003_gene608	1.702e-33	139.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRD1_k127_7163930_4	1160707.AJIK01000034_gene2029	1.055e-49	182.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,26EXD@186818|Planococcaceae	91061|Bacilli	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRD1_k127_7163930_7	927677.ALVU02000001_gene1334	1.528e-31	130.0	COG3548@1|root,COG3548@2|Bacteria,1G8WP@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1211)	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
SRD1_k127_7163930_1	1206741.BAFX01000017_gene7137	6.1e-128	436.0	COG2346@1|root,COG3369@1|root,COG3592@1|root,COG2346@2|Bacteria,COG3369@2|Bacteria,COG3592@2|Bacteria,2GMG5@201174|Actinobacteria,4FZD3@85025|Nocardiaceae	201174|Actinobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	ABM,Bac_globin,Fer4_19,zf-CDGSH
SRD1_k127_7163930_8	38833.XP_003057312.1	0.0005558	48.0	COG2217@1|root,KOG0207@2759|Eukaryota,37HKS@33090|Viridiplantae,34JKK@3041|Chlorophyta	3041|Chlorophyta	P	Heavy-metal-associated domain	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRD1_k127_7163930_3	1380763.BG53_15175	7.661e-53	202.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,26SXM@186822|Paenibacillaceae	91061|Bacilli	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRD1_k127_7163930_0	1304880.JAGB01000003_gene987	1.878e-144	478.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
SRD1_k127_7163930_5	1123226.KB899302_gene2912	1.513e-47	179.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,26TQV@186822|Paenibacillaceae	91061|Bacilli	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRD1_k127_7163930_2	1121422.AUMW01000010_gene1044	7.813e-112	371.0	COG5322@1|root,COG5322@2|Bacteria,1TQ2E@1239|Firmicutes,24A1Y@186801|Clostridia,260IM@186807|Peptococcaceae	186801|Clostridia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7166496_3	484770.UFO1_1578	1.473e-22	102.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD1_k127_7166496_1	401526.TcarDRAFT_1875	6.864e-105	360.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD1_k127_7166496_0	401526.TcarDRAFT_1875	1.402e-106	368.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD1_k127_7166496_2	401526.TcarDRAFT_1875	5.135e-97	338.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD1_k127_7180843_4	479436.Vpar_1490	2.007e-37	142.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4H4P6@909932|Negativicutes	909932|Negativicutes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRD1_k127_7180843_0	635013.TherJR_0299	1.297e-124	404.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,260NI@186807|Peptococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRD1_k127_7180843_5	349161.Dred_0217	1.656e-18	90.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,2632X@186807|Peptococcaceae	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRD1_k127_7180843_2	635013.TherJR_0297	2.786e-46	174.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,26186@186807|Peptococcaceae	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRD1_k127_7180843_1	373903.Hore_01170	2.343e-54	204.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3WAJF@53433|Halanaerobiales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRD1_k127_7180843_3	1121926.AXWO01000002_gene1547	8.378e-40	151.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4EYJQ@85014|Glycomycetales	201174|Actinobacteria	J	Ribosomal protein S10p/S20e	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRD1_k127_7180843_6	502025.Hoch_4022	1.315e-13	70.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2YX6I@29|Myxococcales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRD1_k127_7189063_2	485913.Krac_2434	8.15e-100	334.0	COG1529@1|root,COG1529@2|Bacteria,2G5NF@200795|Chloroflexi	2|Bacteria	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRD1_k127_7189063_5	1382306.JNIM01000001_gene1022	2.206e-58	210.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRD1_k127_7189063_0	1183438.GKIL_3500	2.252e-119	404.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRD1_k127_7189063_3	1123320.KB889664_gene1043	4.004e-72	254.0	COG0697@1|root,COG0697@2|Bacteria,2I91Y@201174|Actinobacteria	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRD1_k127_7189063_1	1170562.Cal6303_1443	2.542e-102	340.0	COG1398@1|root,COG1398@2|Bacteria,1G100@1117|Cyanobacteria,1HJIC@1161|Nostocales	1117|Cyanobacteria	I	PFAM Fatty acid desaturase	ole1	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRD1_k127_7189063_4	1382306.JNIM01000001_gene1703	1.439e-68	248.0	COG0683@1|root,COG0683@2|Bacteria,2G6Q3@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRD1_k127_7191754_1	1123073.KB899241_gene2615	2.337e-08	61.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S9R6@1236|Gammaproteobacteria,1X6GQ@135614|Xanthomonadales	135614|Xanthomonadales	U	Biopolymer	exbD1	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SRD1_k127_7191754_0	1041522.MCOL_V209310	1.896e-49	189.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,2362A@1762|Mycobacteriaceae	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRD1_k127_720512_3	933262.AXAM01000015_gene86	1.128e-27	125.0	COG0632@1|root,COG0632@2|Bacteria,1Q5HB@1224|Proteobacteria,42R4Y@68525|delta/epsilon subdivisions,2WMRB@28221|Deltaproteobacteria,2MJPI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_N
SRD1_k127_720512_2	530564.Psta_3588	6.68e-35	141.0	COG0817@1|root,COG0817@2|Bacteria,2IZJS@203682|Planctomycetes	203682|Planctomycetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRD1_k127_720512_0	562970.Btus_1426	1.823e-81	297.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,277VY@186823|Alicyclobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRD1_k127_720512_1	1121468.AUBR01000005_gene39	9.262e-76	273.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,42FRP@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM penicillin-binding protein transpeptidase	ftsI	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRD1_k127_7217156_3	404589.Anae109_2535	0.0006584	46.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2YVEN@29|Myxococcales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRD1_k127_7217156_1	1452536.JARE01000050_gene2023	5.67e-28	123.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4FKTB@85023|Microbacteriaceae	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRD1_k127_7217156_2	635013.TherJR_2419	1.917e-27	119.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,262EI@186807|Peptococcaceae	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
SRD1_k127_7217156_0	1382306.JNIM01000001_gene2574	3.174e-99	339.0	COG1253@1|root,COG1253@2|Bacteria,2G6D1@200795|Chloroflexi	200795|Chloroflexi	S	CBS domain containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRD1_k127_7227226_3	1043205.AFYF01000018_gene960	1.35e-14	84.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,4FGZS@85021|Intrasporangiaceae	201174|Actinobacteria	S	Anti-sigma K factor RskA	rskA	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRD1_k127_7227226_2	278963.ATWD01000001_gene3078	4.132e-33	136.0	COG1595@1|root,COG1595@2|Bacteria,3Y7HW@57723|Acidobacteria,2JMVS@204432|Acidobacteriia	204432|Acidobacteriia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_7227226_0	56107.Cylst_0471	9.029e-67	246.0	29ZMS@1|root,30I2E@2|Bacteria,1G0J2@1117|Cyanobacteria,1HPFV@1161|Nostocales	1117|Cyanobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SRD1_k127_7227226_1	1380390.JIAT01000002_gene5966	2.949e-65	243.0	COG2215@1|root,COG2215@2|Bacteria,2H0S3@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	NicO
SRD1_k127_7244975_3	941824.TCEL_00822	0.0001975	48.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24U24@186801|Clostridia	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRD1_k127_7244975_1	931627.MycrhDRAFT_1898	2.222e-56	213.0	COG0406@1|root,COG0494@1|root,COG0406@2|Bacteria,COG0494@2|Bacteria,2GNRV@201174|Actinobacteria,2345G@1762|Mycobacteriaceae	201174|Actinobacteria	GL	Belongs to the NUDIX hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRD1_k127_7244975_2	345341.KUTG_00490	6.095e-32	137.0	COG5607@1|root,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria,4EAUR@85010|Pseudonocardiales	201174|Actinobacteria	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
SRD1_k127_7244975_0	1173028.ANKO01000202_gene3448	2.678e-219	715.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria,1H9DA@1150|Oscillatoriales	1117|Cyanobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRD1_k127_7264319_4	1125863.JAFN01000001_gene1427	3.555e-18	92.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2WQ0W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRD1_k127_7264319_1	1234364.AMSF01000005_gene753	2.556e-78	271.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,1RSCZ@1236|Gammaproteobacteria,1X67I@135614|Xanthomonadales	135614|Xanthomonadales	S	LamB/YcsF family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
SRD1_k127_7264319_2	555088.DealDRAFT_1781	2.24e-48	195.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,2485K@186801|Clostridia	186801|Clostridia	E	Allophanate hydrolase subunit 2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
SRD1_k127_7264319_3	1151117.AJLF01000001_gene986	8.655e-44	174.0	COG2049@1|root,arCOG05809@2157|Archaea,2XUMA@28890|Euryarchaeota,242UF@183968|Thermococci	183968|Thermococci	E	Allophanate hydrolase subunit 1	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
SRD1_k127_7264319_0	935948.KE386494_gene372	2.942e-110	389.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,248PD@186801|Clostridia,42FE6@68295|Thermoanaerobacterales	186801|Clostridia	O	COGs COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRD1_k127_7268400_4	1463920.JOGB01000029_gene5666	1.454e-31	143.0	COG0642@1|root,COG2208@1|root,COG0642@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria	201174|Actinobacteria	T	protein phosphatase 2C domain protein	prpE2	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c_2,PAS_4,SpoIIE
SRD1_k127_7268400_3	536019.Mesop_4400	1.205e-58	227.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRD1_k127_7268400_7	1123508.JH636449_gene7262	1.467e-10	68.0	arCOG13559@1|root,33239@2|Bacteria,2J0W1@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
SRD1_k127_7268400_2	941449.dsx2_1272	1.076e-61	232.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2X5JA@28221|Deltaproteobacteria,2MGRV@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRD1_k127_7268400_1	469381.Dpep_0844	3.688e-83	285.0	COG1136@1|root,COG1136@2|Bacteria,3TAPT@508458|Synergistetes	508458|Synergistetes	P	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_7268400_0	401526.TcarDRAFT_0461	4.872e-113	390.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4H2H6@909932|Negativicutes	909932|Negativicutes	V	Efflux ABC transporter permease protein	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRD1_k127_7268400_6	382464.ABSI01000011_gene2994	1.952e-11	76.0	2DQ7E@1|root,3353C@2|Bacteria,46SU5@74201|Verrucomicrobia,2IUQR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
SRD1_k127_7268400_5	747365.Thena_0758	2.977e-30	135.0	COG4783@1|root,COG4783@2|Bacteria,1TVZ0@1239|Firmicutes,25GSM@186801|Clostridia	1239|Firmicutes	M	Zn-dependent protease contains TPR repeats	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRD1_k127_7280289_0	309801.trd_0443	0.0	1090.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi,27XEJ@189775|Thermomicrobia	189775|Thermomicrobia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRD1_k127_7280289_1	251221.35214940	2.892e-108	364.0	COG1092@1|root,COG1092@2|Bacteria,1G4YN@1117|Cyanobacteria	1117|Cyanobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
SRD1_k127_7306867_1	330214.NIDE3182	5.675e-145	471.0	COG0205@1|root,COG0205@2|Bacteria,3J0Y1@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRD1_k127_7306867_4	1345697.M493_17990	8.309e-15	80.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HM6Z@91061|Bacilli,1WFXS@129337|Geobacillus	91061|Bacilli	T	Histidine kinase-like ATPase domain	rsbW	GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRD1_k127_7306867_3	1089553.Tph_c20450	2.154e-71	266.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,42EXG@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRD1_k127_7306867_2	309798.COPRO5265_1036	3.122e-83	287.0	COG3643@1|root,COG3643@2|Bacteria,1TP5T@1239|Firmicutes,24905@186801|Clostridia,42EU0@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Formiminotransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
SRD1_k127_7306867_0	485913.Krac_6820	2.025e-203	646.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRD1_k127_7342561_1	313606.M23134_07681	2.615e-17	93.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47JK5@768503|Cytophagia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRD1_k127_7342561_0	5334.XP_003033858.1	4.221e-54	200.0	COG0339@1|root,KOG2089@2759|Eukaryota,38SFI@33154|Opisthokonta,3NX1E@4751|Fungi,3UZUJ@5204|Basidiomycota,224SF@155619|Agaricomycetes,3W5Q4@5338|Agaricales	4751|Fungi	O	Peptidase family M3	PRD1	GO:0000322,GO:0000323,GO:0000324,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005773,GO:0005794,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0012505,GO:0016787,GO:0019538,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043603,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070011,GO:0070013,GO:0071704,GO:0140096,GO:1901564	3.4.24.37	ko:K01405,ko:K13726	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SRD1_k127_7389078_0	298654.FraEuI1c_0539	1.395e-16	85.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4ET9G@85013|Frankiales	201174|Actinobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRD1_k127_7393322_0	1304880.JAGB01000001_gene687	1.186e-131	445.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRD1_k127_7400181_2	394503.Ccel_1730	1.217e-17	84.0	COG4401@1|root,COG4401@2|Bacteria,1VAID@1239|Firmicutes,24N1H@186801|Clostridia,36KU9@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis	aroH	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
SRD1_k127_7400181_0	1121430.JMLG01000010_gene191	2.979e-127	416.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,260FR@186807|Peptococcaceae	186801|Clostridia	E	PFAM DAHP synthetase I	aroF1	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRD1_k127_7400181_1	309807.SRU_1616	7.05e-33	139.0	COG0287@1|root,COG0287@2|Bacteria,4NEKF@976|Bacteroidetes,1FJ4K@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRD1_k127_7440504_0	926569.ANT_14860	4.216e-126	415.0	COG1167@1|root,COG1167@2|Bacteria,2G61E@200795|Chloroflexi	200795|Chloroflexi	EK	PFAM Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRD1_k127_7440504_3	1121428.DESHY_40215___1	4.169e-70	250.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,260TX@186807|Peptococcaceae	186801|Clostridia	S	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRD1_k127_7440504_1	1449126.JQKL01000006_gene762	2.408e-96	331.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,268B6@186813|unclassified Clostridiales	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRD1_k127_7440504_4	266117.Rxyl_1079	5.055e-61	232.0	COG1606@1|root,COG1606@2|Bacteria,2GPA1@201174|Actinobacteria	201174|Actinobacteria	S	PFAM ExsB family protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,HAD,HAD_2,Hydrolase_like,NAD_synthase
SRD1_k127_7440504_5	1121946.AUAX01000029_gene1996	1.658e-13	83.0	COG0463@1|root,COG2244@1|root,COG0463@2|Bacteria,COG2244@2|Bacteria,2I7M5@201174|Actinobacteria,4DFBM@85008|Micromonosporales	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Polysacc_synt_3
SRD1_k127_7440504_2	483219.LILAB_14535	7.973e-75	273.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WINR@28221|Deltaproteobacteria,2YX29@29|Myxococcales	28221|Deltaproteobacteria	H	Aminotransferase class-III	-	-	2.6.1.55,2.6.1.77	ko:K03851,ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684,R05652	RC00006,RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_7446237_0	1500897.JQNA01000002_gene2689	3.477e-227	709.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VJ8B@28216|Betaproteobacteria,1K0BN@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRD1_k127_7446237_4	649831.L083_5318	0.0008194	49.0	2FJMA@1|root,34BAM@2|Bacteria,2IBW2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4760
SRD1_k127_7446237_1	573413.Spirs_1160	1.577e-30	126.0	COG0454@1|root,COG0456@2|Bacteria,2JB1N@203691|Spirochaetes	203691|Spirochaetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD1_k127_7446237_3	1308866.J416_11165	2.455e-07	57.0	COG1366@1|root,COG1366@2|Bacteria,1VER8@1239|Firmicutes,4HP2I@91061|Bacilli,47172@74385|Gracilibacillus	91061|Bacilli	T	STAS domain	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRD1_k127_7446237_2	1380390.JIAT01000009_gene678	2.607e-23	104.0	2E7G3@1|root,331YZ@2|Bacteria,2IQJZ@201174|Actinobacteria,4CQQW@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7468490_4	1123261.AXDW01000010_gene253	3.202e-19	88.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,1X6HE@135614|Xanthomonadales	135614|Xanthomonadales	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRD1_k127_7468490_2	498761.HM1_1395	7.41e-59	208.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRD1_k127_7468490_3	1449126.JQKL01000050_gene2693	1.118e-32	133.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,268S2@186813|unclassified Clostridiales	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRD1_k127_7468490_0	1121468.AUBR01000044_gene1841	1.331e-122	409.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,42ESN@68295|Thermoanaerobacterales	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRD1_k127_7468490_1	796606.BMMGA3_00800	9.934e-63	225.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,1ZBYM@1386|Bacillus	91061|Bacilli	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRD1_k127_7477051_1	1499967.BAYZ01000055_gene4841	5.433e-76	271.0	COG0287@1|root,COG0287@2|Bacteria	2|Bacteria	E	prephenate dehydrogenase (NADP+) activity	-	-	1.3.1.12,1.5.1.28	ko:K04517,ko:K04940,ko:K06410	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh_C,AlaDh_PNT_C,DpaA_N,NAD_Gly3P_dh_N,Octopine_DH
SRD1_k127_7477051_0	1038860.AXAP01000035_gene4075	1.183e-87	304.0	COG3919@1|root,COG3919@2|Bacteria,1N13P@1224|Proteobacteria,2U3BD@28211|Alphaproteobacteria,3K0WW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
SRD1_k127_7478165_4	56107.Cylst_2452	3.075e-33	132.0	COG1733@1|root,COG1733@2|Bacteria,1G6J8@1117|Cyanobacteria,1HNV6@1161|Nostocales	1117|Cyanobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRD1_k127_7478165_5	452637.Oter_2391	9.554e-24	107.0	COG3558@1|root,COG3558@2|Bacteria,46VBZ@74201|Verrucomicrobia,3K86T@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
SRD1_k127_7478165_1	1210884.HG799466_gene12819	5.443e-139	452.0	COG5002@1|root,COG5002@2|Bacteria,2IXHW@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
SRD1_k127_7478165_2	1123508.JH636440_gene2903	1.721e-64	231.0	COG0745@1|root,COG0745@2|Bacteria,2J32S@203682|Planctomycetes	203682|Planctomycetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRD1_k127_7478165_3	1048834.TC41_0949	1.118e-33	135.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli	91061|Bacilli	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08940	DMRL_synthase
SRD1_k127_7478165_0	1123376.AUIU01000007_gene1178	5.766e-157	507.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,3J0E0@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRD1_k127_7478165_6	1463920.JOGB01000043_gene1631	0.0003324	50.0	2FJMA@1|root,344HE@2|Bacteria,2GTDW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7478194_4	665571.STHERM_c08610	2.096e-27	118.0	COG0526@1|root,COG0526@2|Bacteria,2J8ET@203691|Spirochaetes	203691|Spirochaetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRD1_k127_7478194_3	1009370.ALO_19052	1.097e-35	139.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,4H4QP@909932|Negativicutes	909932|Negativicutes	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRD1_k127_7478194_2	720554.Clocl_0677	3.964e-37	147.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia,3WJ3F@541000|Ruminococcaceae	186801|Clostridia	M	Transglycosylase SLT domain	yjbJ	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
SRD1_k127_7478194_1	373903.Hore_17610	2.775e-43	174.0	COG0795@1|root,COG1452@1|root,COG0795@2|Bacteria,COG1452@2|Bacteria,1UZNX@1239|Firmicutes,24F8X@186801|Clostridia,3WAEC@53433|Halanaerobiales	186801|Clostridia	M	Permease YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
SRD1_k127_7478194_5	748449.Halha_2433	7.409e-12	79.0	COG1452@1|root,COG1452@2|Bacteria,1W2IS@1239|Firmicutes	1239|Firmicutes	M	Organic solvent tolerance protein OstA	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
SRD1_k127_7478194_0	316067.Geob_3094	2.592e-50	199.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRD1_k127_7482892_3	1382306.JNIM01000001_gene1170	1.528e-77	262.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_7482892_4	485913.Krac_11109	1.329e-74	257.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_7482892_2	521460.Athe_1801	1.526e-80	275.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,42EW3@68295|Thermoanaerobacterales	186801|Clostridia	D	TIGRFAM Cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRD1_k127_7482892_8	1232428.CAVO010000017_gene905	4.229e-42	170.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4H36P@909932|Negativicutes	909932|Negativicutes	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRD1_k127_7482892_7	1089553.Tph_c06550	2.23e-53	212.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,42FSF@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM Peptidase M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRD1_k127_7482892_5	1449126.JQKL01000003_gene1752	6.143e-74	266.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,267T5@186813|unclassified Clostridiales	186801|Clostridia	M	tail specific protease	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRD1_k127_7482892_6	102232.GLO73106DRAFT_00026240	6.897e-65	239.0	COG0793@1|root,COG0793@2|Bacteria,1G1YJ@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41,Tricorn_C1
SRD1_k127_7482892_0	479434.Sthe_2381	3.045e-253	797.0	COG0365@1|root,COG0365@2|Bacteria,2G830@200795|Chloroflexi,27XH3@189775|Thermomicrobia	189775|Thermomicrobia	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRD1_k127_7482892_1	1382306.JNIM01000001_gene665	1.138e-123	420.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRD1_k127_7500823_0	1303518.CCALI_02346	4.343e-112	370.0	COG0171@1|root,COG0171@2|Bacteria	2|Bacteria	H	NAD+ synthase (glutamine-hydrolyzing) activity	nadE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
SRD1_k127_7500823_7	211114.JOEF01000008_gene1234	8.003e-07	57.0	COG0346@1|root,COG0346@2|Bacteria,2IHXI@201174|Actinobacteria,4E4PR@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRD1_k127_7500823_5	1089551.KE386572_gene695	2.206e-22	106.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,4BSEE@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRD1_k127_7500823_1	562970.Btus_1602	1.362e-97	332.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli,2782Z@186823|Alicyclobacillaceae	91061|Bacilli	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRD1_k127_7500823_3	1297742.A176_02454	1.56e-30	139.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42Q14@68525|delta/epsilon subdivisions,2WJ8C@28221|Deltaproteobacteria,2YX9F@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
SRD1_k127_7500823_2	1463887.KL589953_gene42	3.74e-55	201.0	COG0580@1|root,COG0580@2|Bacteria,2IG6C@201174|Actinobacteria	201174|Actinobacteria	G	Major intrinsic protein	-	-	-	-	-	-	-	-	-	-	-	-	MIP
SRD1_k127_7500823_4	926549.KI421517_gene1103	3.308e-27	121.0	COG0221@1|root,COG0221@2|Bacteria,4NUA4@976|Bacteroidetes,47VDT@768503|Cytophagia	976|Bacteroidetes	C	Inorganic pyrophosphatase	-	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRD1_k127_7500823_6	1158050.KB895452_gene554	3.838e-14	78.0	COG0531@1|root,COG0531@2|Bacteria,2GMTD@201174|Actinobacteria,1WAT8@1268|Micrococcaceae	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRD1_k127_7519595_0	1382306.JNIM01000001_gene1561	9e-323	1012.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2G64C@200795|Chloroflexi	200795|Chloroflexi	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SRD1_k127_7525597_1	864051.BurJ1DRAFT_4252	8.829e-09	64.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,1KKUJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRD1_k127_7525597_0	868864.Dester_0055	1.507e-86	294.0	COG0439@1|root,COG0439@2|Bacteria,2G3KR@200783|Aquificae	200783|Aquificae	I	acetyl-CoA carboxylase, biotin carboxylase	accC_1	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRD1_k127_7532092_1	1500304.JQKY01000013_gene3544	7.619e-134	436.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,4B7FG@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRD1_k127_7532092_0	1121861.KB899917_gene3716	7.54e-172	551.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	srrA1	-	-	ko:K02027,ko:K17244	ko02010,map02010	M00207,M00601	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.40	-	-	SBP_bac_1,SBP_bac_8
SRD1_k127_7532092_3	1121861.KB899917_gene3717	7.657e-117	384.0	COG1175@1|root,COG1175@2|Bacteria,1NAGS@1224|Proteobacteria,2TUXQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type sugar transport systems permease components	-	-	-	ko:K02025,ko:K10118	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
SRD1_k127_7532092_2	1121861.KB899917_gene3718	4.165e-117	398.0	COG0395@1|root,COG0395@2|Bacteria,1R4GU@1224|Proteobacteria	1224|Proteobacteria	P	Binding-protein-dependent transport system inner membrane component	ycjP_1	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRD1_k127_7532092_4	1380391.JIAS01000015_gene109	2.857e-33	140.0	COG0111@1|root,COG0111@2|Bacteria,1R76G@1224|Proteobacteria,2VGNT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRD1_k127_7532092_6	1267535.KB906767_gene1583	9.938e-10	63.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,3Y2Z0@57723|Acidobacteria,2JI83@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
SRD1_k127_7545322_3	1396141.BATP01000032_gene4419	2.932e-63	221.0	COG3837@1|root,COG3837@2|Bacteria,46T0V@74201|Verrucomicrobia,2IU8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD1_k127_7545322_0	649638.Trad_2075	7.964e-209	666.0	COG1217@1|root,COG1217@2|Bacteria,1WINQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRD1_k127_7545322_2	314345.SPV1_10621	1.967e-70	246.0	COG1611@1|root,COG3350@1|root,COG1611@2|Bacteria,COG3350@2|Bacteria,1R8EU@1224|Proteobacteria	1224|Proteobacteria	S	YHS domain	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	YHS
SRD1_k127_7545322_1	1210884.HG799464_gene10982	6.236e-122	411.0	COG1236@1|root,COG1236@2|Bacteria,2IXNS@203682|Planctomycetes	203682|Planctomycetes	J	Exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
SRD1_k127_7545662_21	639030.JHVA01000001_gene2431	3.375e-26	118.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria,2JHPY@204432|Acidobacteriia	204432|Acidobacteriia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRD1_k127_7545662_7	1120973.AQXL01000131_gene2036	2.197e-134	436.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,2788A@186823|Alicyclobacillaceae	91061|Bacilli	C	Transketolase, pyrimidine binding domain	dxpS	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRD1_k127_7545662_10	479434.Sthe_3477	1.035e-105	353.0	COG1071@1|root,COG1071@2|Bacteria,2GAC3@200795|Chloroflexi,27Z5H@189775|Thermomicrobia	189775|Thermomicrobia	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRD1_k127_7545662_1	1120973.AQXL01000119_gene596	7.088e-179	574.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,278X6@186823|Alicyclobacillaceae	91061|Bacilli	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
SRD1_k127_7545662_6	525904.Tter_2189	2.305e-136	456.0	COG1215@1|root,COG1215@2|Bacteria,2NPD4@2323|unclassified Bacteria	2|Bacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
SRD1_k127_7545662_28	1123267.JONN01000001_gene733	5.533e-12	78.0	COG1413@1|root,COG1413@2|Bacteria,1N7UC@1224|Proteobacteria,2UGUW@28211|Alphaproteobacteria,2KA0S@204457|Sphingomonadales	204457|Sphingomonadales	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRD1_k127_7545662_15	1380354.JIAN01000009_gene3702	3.338e-32	134.0	COG0745@1|root,COG0745@2|Bacteria,2IQWH@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRD1_k127_7545662_22	292459.STH2399	2.923e-25	111.0	COG0745@1|root,COG0745@2|Bacteria,1VHJ1@1239|Firmicutes,24QWF@186801|Clostridia	186801|Clostridia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRD1_k127_7545662_0	1144275.COCOR_00554	3.315e-199	652.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria,2YTZK@29|Myxococcales	28221|Deltaproteobacteria	CE	Peptidase family M1 domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,HEAT_2,Peptidase_M1
SRD1_k127_7545662_3	1125863.JAFN01000001_gene3002	1.539e-148	504.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	elongation factor G domain IV	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRD1_k127_7545662_17	292415.Tbd_2203	2.806e-31	132.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2VGZ7@28216|Betaproteobacteria,1KSQN@119069|Hydrogenophilales	119069|Hydrogenophilales	O	4Fe-4S single cluster domain	-	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
SRD1_k127_7545662_29	1410665.JNKR01000002_gene1722	2.646e-11	71.0	COG0720@1|root,COG0720@2|Bacteria,1VAJX@1239|Firmicutes,4H58Z@909932|Negativicutes	909932|Negativicutes	H	queuosine biosynthesis protein QueD	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRD1_k127_7545662_32	265072.Mfla_0049	0.0004293	46.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2VVUH@28216|Betaproteobacteria,2KN43@206350|Nitrosomonadales	206350|Nitrosomonadales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRD1_k127_7545662_27	1286093.C266_23236	2.125e-14	84.0	COG2030@1|root,COG2030@2|Bacteria,1NDST@1224|Proteobacteria,2VY7N@28216|Betaproteobacteria,1K2TC@119060|Burkholderiaceae	28216|Betaproteobacteria	I	PFAM MaoC domain protein dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1289,MaoC_dehydrat_N,MaoC_dehydratas
SRD1_k127_7545662_26	1159870.KB907784_gene688	4.177e-15	83.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2VUEV@28216|Betaproteobacteria,3T48Y@506|Alcaligenaceae	28216|Betaproteobacteria	S	Acyl-CoA thioesterase	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
SRD1_k127_7545662_30	1569209.BBPH01000130_gene2864	5.502e-08	60.0	COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria,2U9MH@28211|Alphaproteobacteria,2PWY7@265|Paracoccus	28211|Alphaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRD1_k127_7545662_20	330214.NIDE1847	2.34e-28	121.0	2DQ7E@1|root,3353C@2|Bacteria,3J1EM@40117|Nitrospirae	40117|Nitrospirae	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
SRD1_k127_7545662_14	1121382.JQKG01000019_gene1278	5.23e-33	138.0	COG3694@1|root,COG3694@2|Bacteria,1WM9D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_6
SRD1_k127_7545662_12	665959.HMPREF1013_01724	1.058e-44	176.0	COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,4HBVU@91061|Bacilli,1ZBKH@1386|Bacillus	91061|Bacilli	S	ABC transporter (permease)	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
SRD1_k127_7545662_19	671143.DAMO_0021	4.797e-30	135.0	COG3055@1|root,COG3055@2|Bacteria,2NPM4@2323|unclassified Bacteria	2|Bacteria	G	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6
SRD1_k127_7545662_8	292459.STH2664	3.517e-123	406.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,247KC@186801|Clostridia	186801|Clostridia	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRD1_k127_7545662_25	1248760.ANFZ01000002_gene3078	1.163e-16	84.0	COG2105@1|root,COG2105@2|Bacteria,1N80E@1224|Proteobacteria,2U5YU@28211|Alphaproteobacteria,2K78W@204457|Sphingomonadales	204457|Sphingomonadales	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
SRD1_k127_7545662_11	1267535.KB906767_gene1755	9.103e-76	289.0	COG3240@1|root,COG4993@1|root,COG3240@2|Bacteria,COG4993@2|Bacteria,3Y2WV@57723|Acidobacteria,2JKWV@204432|Acidobacteriia	204432|Acidobacteriia	G	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ
SRD1_k127_7545662_31	543632.JOJL01000005_gene4835	8.03e-05	57.0	COG3979@1|root,COG3979@2|Bacteria,2H72H@201174|Actinobacteria,4DJJD@85008|Micromonosporales	201174|Actinobacteria	S	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7545662_16	864702.OsccyDRAFT_5002	7.108e-32	146.0	COG1028@1|root,COG2133@1|root,COG1028@2|Bacteria,COG2133@2|Bacteria,1G2IN@1117|Cyanobacteria,1H8RG@1150|Oscillatoriales	1117|Cyanobacteria	IQ	Short-chain dehydrogenase reductase Sdr	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
SRD1_k127_7545662_9	861299.J421_1879	2.24e-116	389.0	COG1252@1|root,COG1252@2|Bacteria,1ZT8C@142182|Gemmatimonadetes	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRD1_k127_7545662_2	562970.Btus_0523	3.324e-159	529.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,1V255@1239|Firmicutes,4HFUF@91061|Bacilli,278TP@186823|Alicyclobacillaceae	91061|Bacilli	M	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Cytochrom_D1,Lactonase,Phosphoesterase
SRD1_k127_7545662_24	1122603.ATVI01000012_gene1227	1.929e-19	100.0	COG3837@1|root,COG3837@2|Bacteria,1N15Q@1224|Proteobacteria,1T07G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD1_k127_7545662_18	103690.17135270	1.521e-30	134.0	COG0491@1|root,COG0491@2|Bacteria,1G4UY@1117|Cyanobacteria,1HM6G@1161|Nostocales	1117|Cyanobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_5
SRD1_k127_7545662_23	232348.ADXL01000039_gene1679	7.113e-22	106.0	COG2197@1|root,COG2197@2|Bacteria,1G1TZ@1117|Cyanobacteria,1GYRN@1129|Synechococcus	1117|Cyanobacteria	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	ycf29	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD1_k127_7545662_13	1111479.AXAR01000012_gene1372	5.551e-40	171.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli	91061|Bacilli	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
SRD1_k127_7545662_4	215803.DB30_4326	7.099e-146	507.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WIW8@28221|Deltaproteobacteria,2YU7C@29|Myxococcales	28221|Deltaproteobacteria	KL	helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
SRD1_k127_7545662_5	479432.Sros_4546	6.122e-137	449.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria	201174|Actinobacteria	E	decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRD1_k127_7545905_0	234267.Acid_2317	5.024e-87	299.0	COG1171@1|root,COG1171@2|Bacteria,3Y2RI@57723|Acidobacteria	57723|Acidobacteria	E	beta' subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
SRD1_k127_7545905_3	562970.Btus_1294	1.419e-24	109.0	COG0526@1|root,COG0526@2|Bacteria,1V1R4@1239|Firmicutes,4HFWU@91061|Bacilli,278EK@186823|Alicyclobacillaceae	91061|Bacilli	CO	Thioredoxin-like	ykuV	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRD1_k127_7545905_2	316274.Haur_0442	1.034e-35	141.0	COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi,377DW@32061|Chloroflexia	32061|Chloroflexia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRD1_k127_7545905_1	1449347.JQLN01000007_gene1527	1.168e-53	198.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Peptidase_S8
SRD1_k127_7553448_0	329726.AM1_3791	2.188e-36	157.0	COG3206@1|root,COG3206@2|Bacteria,1GQNN@1117|Cyanobacteria	1117|Cyanobacteria	M	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRD1_k127_7553448_3	1380391.JIAS01000013_gene3828	5.579e-32	139.0	COG1595@1|root,COG1595@2|Bacteria,1RHRR@1224|Proteobacteria,2U9G0@28211|Alphaproteobacteria,2JS74@204441|Rhodospirillales	204441|Rhodospirillales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRD1_k127_7553448_4	1380394.JADL01000010_gene4101	1.133e-20	95.0	COG0662@1|root,COG0662@2|Bacteria,1N71F@1224|Proteobacteria,2UFSH@28211|Alphaproteobacteria,2JUW5@204441|Rhodospirillales	204441|Rhodospirillales	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD1_k127_7553448_2	1071679.BG57_03280	3.427e-34	142.0	2D9QC@1|root,336IT@2|Bacteria,1R3C8@1224|Proteobacteria,2WIGR@28216|Betaproteobacteria,1KGA6@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7553448_1	1071679.BG57_03280	6.362e-35	143.0	2D9QC@1|root,336IT@2|Bacteria,1R3C8@1224|Proteobacteria,2WIGR@28216|Betaproteobacteria,1KGA6@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7588873_0	1121346.KB899817_gene3164	1.552e-92	310.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,26R0C@186822|Paenibacillaceae	91061|Bacilli	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRD1_k127_7588873_1	926550.CLDAP_07830	3.566e-28	132.0	COG4447@1|root,COG4447@2|Bacteria,2G66V@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRD1_k127_7604201_1	1303518.CCALI_02907	3.02e-87	306.0	COG5267@1|root,COG5267@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
SRD1_k127_7604201_0	1382306.JNIM01000001_gene706	1.337e-99	339.0	COG4102@1|root,COG4102@2|Bacteria,2G79B@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRD1_k127_7614597_1	228410.NE2264	9.586e-89	302.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2VH1G@28216|Betaproteobacteria,37202@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
SRD1_k127_7614597_0	1123368.AUIS01000009_gene2506	2.915e-124	402.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,2NC9C@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRD1_k127_7616411_1	1122963.AUHB01000017_gene1994	1.768e-36	147.0	COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,2U0RG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRD1_k127_7616411_0	1128421.JAGA01000004_gene2673	1.05e-196	625.0	COG0519@1|root,COG0519@2|Bacteria,2NNRS@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iJN746.PP_1032,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833	GATase,GMP_synt_C,NAD_synthase
SRD1_k127_7640917_2	1265502.KB905946_gene1130	2.104e-44	166.0	COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,2VQA1@28216|Betaproteobacteria,4ADNK@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM flavin reductase domain protein, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRD1_k127_7640917_1	1163617.SCD_n00104	3.953e-100	351.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria	28216|Betaproteobacteria	EH	Aminotransferase class IV	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
SRD1_k127_7640917_0	323848.Nmul_A1991	1.36e-136	444.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria,3721U@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
SRD1_k127_7658427_1	1121924.ATWH01000010_gene1007	2.246e-64	226.0	COG1309@1|root,COG1309@2|Bacteria,2I8Z7@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD1_k127_7658427_0	1380390.JIAT01000013_gene123	9.356e-284	893.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	yvaM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C,Hydrolase_4
SRD1_k127_7671228_1	272624.lpg1678	5.15e-130	452.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1JDPB@118969|Legionellales	118969|Legionellales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRD1_k127_7671228_2	126957.SMAR000022-PA	5.299e-83	302.0	COG0152@1|root,KOG2835@2759|Eukaryota,38BXP@33154|Opisthokonta,3BDBW@33208|Metazoa,3CVID@33213|Bilateria,41UM7@6656|Arthropoda	33208|Metazoa	F	It is involved in the biological process described with 'de novo' IMP biosynthetic process	PAICS	GO:0000082,GO:0000278,GO:0003674,GO:0003824,GO:0004638,GO:0004639,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022402,GO:0034641,GO:0034654,GO:0042440,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0046040,GO:0046112,GO:0046148,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903047	4.1.1.21,6.3.2.6	ko:K01587	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04209,R04591	RC00064,RC00162,RC00590	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,Myb_DNA-bind_4,SAICAR_synt
SRD1_k127_7671228_0	926550.CLDAP_23750	2.692e-135	445.0	COG0015@1|root,COG0015@2|Bacteria,2G607@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2,5.5.1.2	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	M00048,M00049	R01083,R03307,R04559	RC00379,RC00444,RC00445,RC00902	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
SRD1_k127_7671228_3	929556.Solca_4153	2.092e-49	181.0	COG1670@1|root,COG1670@2|Bacteria,4NQB5@976|Bacteroidetes,1ITC7@117747|Sphingobacteriia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRD1_k127_7671389_3	316274.Haur_0945	3.816e-36	147.0	COG0299@1|root,COG0299@2|Bacteria,2G6ZJ@200795|Chloroflexi,375JQ@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRD1_k127_7671389_0	1128421.JAGA01000002_gene1645	1.276e-142	475.0	COG0469@1|root,COG0469@2|Bacteria,2NNKX@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the pyruvate kinase family	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iAF987.Gmet_0122	PK,PK_C
SRD1_k127_7671389_1	926692.AZYG01000040_gene1496	4.22e-97	335.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,3WA6G@53433|Halanaerobiales	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRD1_k127_7671389_2	204773.HEAR0704	5.326e-44	164.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2VR8T@28216|Betaproteobacteria,473F8@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
SRD1_k127_767403_6	204669.Acid345_2973	1.15e-22	103.0	COG0581@1|root,COG0581@2|Bacteria,3Y3JF@57723|Acidobacteria,2JHVP@204432|Acidobacteriia	204432|Acidobacteriia	P	Phosphate transport system permease protein PstA	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRD1_k127_767403_1	768710.DesyoDRAFT_3277	2.034e-89	308.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,26553@186807|Peptococcaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRD1_k127_767403_0	562970.Btus_2535	1.009e-120	396.0	COG0226@1|root,COG0226@2|Bacteria,1TYCT@1239|Firmicutes,4I7GX@91061|Bacilli,279TX@186823|Alicyclobacillaceae	91061|Bacilli	P	Belongs to the PstS family	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRD1_k127_767403_4	574087.Acear_0866	4.426e-60	215.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,3WANJ@53433|Halanaerobiales	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRD1_k127_767403_3	1121430.JMLG01000003_gene597	1.994e-67	245.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,260MY@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SRD1_k127_767403_2	326427.Cagg_1100	1.42e-72	253.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,3752X@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_767403_5	441620.Mpop_3361	6.047e-30	135.0	COG1807@1|root,COG1807@2|Bacteria,1R77I@1224|Proteobacteria,2U3HK@28211|Alphaproteobacteria,1JSJK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRD1_k127_767403_7	903818.KI912268_gene2452	2.462e-11	67.0	COG0013@1|root,COG0013@2|Bacteria,3Y359@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRD1_k127_7682891_3	1463920.JOGB01000006_gene199	7.948e-35	147.0	COG0596@1|root,COG0596@2|Bacteria,2GNFU@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRD1_k127_7682891_4	1183438.GKIL_4381	9.688e-21	108.0	COG1404@1|root,COG3386@1|root,COG1404@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,P_proprotein,Peptidase_S8,VCBS
SRD1_k127_7682891_0	401526.TcarDRAFT_0202	3.355e-133	437.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H2ZB@909932|Negativicutes	909932|Negativicutes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.82	ko:K09251	ko00330,ko01100,map00330,map01100	-	R01155	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_7682891_2	1009370.ALO_13809	8.798e-39	151.0	COG2867@1|root,COG2867@2|Bacteria,1V5PS@1239|Firmicutes,4H4DX@909932|Negativicutes	909932|Negativicutes	I	Cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRD1_k127_7682891_1	273068.TTE2374	6.456e-109	363.0	COG5322@1|root,COG5322@2|Bacteria,1TSXZ@1239|Firmicutes,24992@186801|Clostridia,42EPQ@68295|Thermoanaerobacterales	186801|Clostridia	S	Shikimate quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
SRD1_k127_7683841_1	525904.Tter_0021	8.673e-121	400.0	COG0304@1|root,COG0304@2|Bacteria,2NNSX@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabB	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRD1_k127_7683841_2	479434.Sthe_1005	4.978e-40	156.0	COG2867@1|root,COG2867@2|Bacteria	2|Bacteria	I	negative regulation of translational initiation	-	-	-	ko:K05554,ko:K15885	ko01056,ko01130,map01056,map01130	M00778	R09265,R09268	RC02546,RC02547	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Polyketide_cyc,Polyketide_cyc2
SRD1_k127_7683841_4	479434.Sthe_1006	3.939e-35	151.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	fixC	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,Trp_halogenase
SRD1_k127_7683841_3	324057.Pjdr2_2585	1.597e-37	149.0	COG0500@1|root,COG2226@2|Bacteria,1V1WV@1239|Firmicutes,4HFQ9@91061|Bacilli,26SKG@186822|Paenibacillaceae	91061|Bacilli	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRD1_k127_7683841_0	2423.NA23_0205420	2.439e-205	657.0	COG1012@1|root,COG1012@2|Bacteria,2GCJA@200918|Thermotogae	200918|Thermotogae	C	PFAM Aldehyde dehydrogenase	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRD1_k127_7683841_5	1123388.AQWU01000051_gene1445	1.225e-17	87.0	COG1167@1|root,COG1167@2|Bacteria,1WI26@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EK	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRD1_k127_7733790_2	1382356.JQMP01000004_gene437	5.892e-99	329.0	COG0133@1|root,COG0133@2|Bacteria,2G5Q3@200795|Chloroflexi,27XJP@189775|Thermomicrobia	189775|Thermomicrobia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD1_k127_7733790_5	1123257.AUFV01000001_gene1586	8.325e-57	210.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,1X40W@135614|Xanthomonadales	135614|Xanthomonadales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRD1_k127_7733790_6	367299.JOEE01000008_gene482	1.909e-16	84.0	2C9IE@1|root,31AT3@2|Bacteria,2IM6M@201174|Actinobacteria,4FH07@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4383
SRD1_k127_7733790_3	456442.Mboo_2020	3.016e-94	319.0	COG0111@1|root,arCOG01754@2157|Archaea,2XU9V@28890|Euryarchaeota	28890|Euryarchaeota	E	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRD1_k127_7733790_1	266117.Rxyl_2760	5.57e-136	443.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria,4CPGH@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRD1_k127_7733790_0	1191523.MROS_1560	3.102e-218	691.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3169	PEPCK_ATP
SRD1_k127_7733790_4	1122221.JHVI01000014_gene1360	2.596e-63	223.0	COG1171@1|root,COG1171@2|Bacteria,1WJZG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD1_k127_7736364_0	56107.Cylst_0472	9.202e-93	321.0	COG0457@1|root,COG0457@2|Bacteria,1GI5Z@1117|Cyanobacteria,1HT1F@1161|Nostocales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7736364_2	1227360.C176_10757	2.314e-18	90.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4HBBF@91061|Bacilli,26D26@186818|Planococcaceae	91061|Bacilli	S	Belongs to the peptidase M16 family	mlpA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRD1_k127_7738610_2	670487.Ocepr_0165	1.382e-39	153.0	COG0745@1|root,COG0745@2|Bacteria,1WJQC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07664	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_7738610_0	234267.Acid_4911	4.836e-157	511.0	2EX9M@1|root,33QKC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7738610_1	457570.Nther_2188	2.46e-44	182.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRD1_k127_7738610_3	649831.L083_4855	9.672e-11	64.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4D8KN@85008|Micromonosporales	201174|Actinobacteria	E	amino acid	rocE	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRD1_k127_7763614_0	469383.Cwoe_4113	8.851e-106	365.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4CPP1@84995|Rubrobacteria	84995|Rubrobacteria	C	xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRD1_k127_7763614_1	1123288.SOV_4c04230	9.389e-93	329.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD1_k127_7771127_8	279010.BL00110	0.0004631	45.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,1ZBTZ@1386|Bacillus	91061|Bacilli	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
SRD1_k127_7771127_4	888062.HMPREF9083_0575	1.768e-23	110.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4H41I@909932|Negativicutes	909932|Negativicutes	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRD1_k127_7771127_3	1293054.HSACCH_01676	3.187e-31	135.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,3WAP9@53433|Halanaerobiales	186801|Clostridia	U	TIGRFAM membrane protein insertase, YidC Oxa1 family	oxaA	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRD1_k127_7771127_5	525263.HMPREF0298_1747	4.491e-19	96.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,22PAT@1653|Corynebacteriaceae	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRD1_k127_7771127_7	1123389.ATXJ01000012_gene2083	6.491e-08	61.0	COG0594@1|root,COG0594@2|Bacteria,1WKD9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRD1_k127_7771127_6	1304275.C41B8_10430	4.445e-11	66.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRD1_k127_7771127_0	315750.BPUM_0001	9.439e-145	473.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,1ZBKI@1386|Bacillus	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRD1_k127_7771127_2	926561.KB900621_gene2726	1.724e-57	215.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,3WA84@53433|Halanaerobiales	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRD1_k127_7771127_1	292459.STH4	1.982e-61	227.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRD1_k127_7815453_2	525904.Tter_1921	2.06e-39	153.0	COG5516@1|root,COG5516@2|Bacteria	2|Bacteria	S	CGNR zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRD1_k127_7815453_5	861299.J421_6009	3.925e-15	78.0	2E328@1|root,32Y2G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7815453_1	643648.Slip_1953	4.341e-80	280.0	COG1208@1|root,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,24AGU@186801|Clostridia,42K9R@68298|Syntrophomonadaceae	186801|Clostridia	M	transferase hexapeptide repeat containing protein	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRD1_k127_7815453_0	323848.Nmul_A0715	8.787e-302	950.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VM4W@28216|Betaproteobacteria,372UR@32003|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRD1_k127_7815453_3	1303518.CCALI_01606	1.152e-38	159.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	ko:K14274,ko:K20276	ko00040,ko02024,map00040,map02024	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	DUF5122,He_PIG,SBBP,SGL
SRD1_k127_7827542_1	521098.Aaci_0254	7.291e-48	179.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,4HCQ3@91061|Bacilli,2795G@186823|Alicyclobacillaceae	91061|Bacilli	T	PFAM Osmosensitive K channel His kinase sensor	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	KdpD,Usp
SRD1_k127_7827542_0	1540221.JQNI01000002_gene2498	6.969e-56	215.0	COG0642@1|root,COG2205@2|Bacteria,1WME7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
SRD1_k127_7830672_6	298653.Franean1_2048	3.628e-33	133.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4ESVT@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
SRD1_k127_7830672_3	498761.HM1_1931	8.888e-83	291.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia	186801|Clostridia	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
SRD1_k127_7830672_5	1128421.JAGA01000003_gene3265	8.595e-62	222.0	COG0266@1|root,COG0266@2|Bacteria,2NPGY@2323|unclassified Bacteria	2|Bacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRD1_k127_7830672_0	1121468.AUBR01000058_gene881	4.367e-211	686.0	COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,42FDS@68295|Thermoanaerobacterales	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRD1_k127_7830672_4	1121423.JONT01000012_gene393	1.662e-63	233.0	COG2271@1|root,COG2271@2|Bacteria,1UJAW@1239|Firmicutes,25F03@186801|Clostridia,263F1@186807|Peptococcaceae	186801|Clostridia	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
SRD1_k127_7830672_8	69395.JQLZ01000012_gene4283	1.995e-18	94.0	COG1266@1|root,COG1266@2|Bacteria,1NFV7@1224|Proteobacteria,2V70Q@28211|Alphaproteobacteria,2KJMQ@204458|Caulobacterales	204458|Caulobacterales	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRD1_k127_7830672_7	1463909.KL585966_gene444	2.254e-29	119.0	COG1146@1|root,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K05524	-	-	R10159	-	ko00000,ko01000	-	-	-	Fer4,Fer4_4,Pyr_redox_2
SRD1_k127_7830672_2	1313172.YM304_30930	1.019e-119	394.0	COG3383@1|root,COG3383@2|Bacteria,2GKBP@201174|Actinobacteria	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,NADH-G_4Fe-4S_3
SRD1_k127_7830672_1	2074.JNYD01000022_gene1409	6.321e-180	578.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4E076@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.17.1.9,1.6.5.3	ko:K00122,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
SRD1_k127_7853964_1	518766.Rmar_1784	9.976e-136	446.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,4NFTI@976|Bacteroidetes,1FITQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRD1_k127_7853964_0	395495.Lcho_2036	5.155e-136	458.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,1KKDW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRD1_k127_7870178_1	1521187.JPIM01000084_gene664	1.632e-58	233.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,2G87Y@200795|Chloroflexi,376D4@32061|Chloroflexia	32061|Chloroflexia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS_8
SRD1_k127_7870178_0	926569.ANT_23640	4.899e-84	301.0	COG2114@1|root,COG2203@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2G6X8@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc,PAS
SRD1_k127_7870178_2	1196323.ALKF01000205_gene4190	1.7e-06	58.0	COG1558@1|root,COG1558@2|Bacteria,1V6NB@1239|Firmicutes,4HH4W@91061|Bacilli,26XHN@186822|Paenibacillaceae	91061|Bacilli	N	Belongs to the flagella basal body rod proteins family	flgC	GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
SRD1_k127_7875246_0	1198114.AciX9_2438	2.703e-264	826.0	COG2216@1|root,COG2216@2|Bacteria,3Y302@57723|Acidobacteria,2JHQI@204432|Acidobacteriia	204432|Acidobacteriia	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
SRD1_k127_7875246_1	1040982.AXAL01000013_gene4508	1.104e-59	213.0	COG2156@1|root,COG2156@2|Bacteria,1RABG@1224|Proteobacteria,2TSQ7@28211|Alphaproteobacteria,43JU6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
SRD1_k127_7887172_0	1341151.ASZU01000004_gene157	5.072e-105	357.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,27BGA@186824|Thermoactinomycetaceae	91061|Bacilli	E	C-terminus of AA_permease	yfnA	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRD1_k127_7904868_0	760568.Desku_2292	8.139e-86	289.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,2602N@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRD1_k127_7904868_1	1382304.JNIL01000001_gene276	7.433e-49	185.0	COG3511@1|root,COG3511@2|Bacteria,1U22R@1239|Firmicutes,4HCD7@91061|Bacilli,279H4@186823|Alicyclobacillaceae	91061|Bacilli	M	Phosphoesterase family	-	-	3.1.3.64	ko:K21302	ko00562,ko01100,ko05152,map00562,map01100,map05152	-	-	-	ko00000,ko00001,ko01000	-	-	-	Phosphoesterase
SRD1_k127_7913834_0	867903.ThesuDRAFT_00760	5.35e-75	256.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,3WCG0@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SRD1_k127_7913834_2	671143.DAMO_1357	1.101e-07	64.0	COG1466@1|root,COG1466@2|Bacteria,2NPN5@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta,DNA_pol3_gamma3
SRD1_k127_7913834_1	929562.Emtol_2322	7.658e-10	61.0	COG1670@1|root,COG1670@2|Bacteria,4NQB5@976|Bacteroidetes,47RAN@768503|Cytophagia	976|Bacteroidetes	J	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRD1_k127_7916568_4	661478.OP10G_0763	5.532e-13	82.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRD1_k127_7916568_2	204669.Acid345_1615	2.059e-21	108.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
SRD1_k127_7916568_1	1068978.AMETH_2724	6.376e-65	226.0	COG1765@1|root,COG1765@2|Bacteria,2IIUB@201174|Actinobacteria,4E3VV@85010|Pseudonocardiales	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRD1_k127_7916568_0	497964.CfE428DRAFT_0631	4.196e-154	509.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRD1_k127_7925520_3	378806.STAUR_2110	1.475e-40	154.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42NA6@68525|delta/epsilon subdivisions,2WIMU@28221|Deltaproteobacteria,2YU9T@29|Myxococcales	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRD1_k127_7925520_6	469383.Cwoe_4791	1.299e-33	137.0	COG3797@1|root,COG3797@2|Bacteria,2GPDB@201174|Actinobacteria	201174|Actinobacteria	I	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRD1_k127_7925520_7	1071679.BG57_03280	1.426e-28	125.0	2D9QC@1|root,336IT@2|Bacteria,1R3C8@1224|Proteobacteria,2WIGR@28216|Betaproteobacteria,1KGA6@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7925520_10	525909.Afer_1115	0.0005096	49.0	2BM3X@1|root,32FM8@2|Bacteria,2HH03@201174|Actinobacteria,4CP0F@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7925520_8	1040989.AWZU01000041_gene6043	1.602e-24	108.0	COG0590@1|root,COG0590@2|Bacteria,1R1KN@1224|Proteobacteria,2TZCD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	FJ	Protein of unknown function (DUF3175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3175
SRD1_k127_7925520_9	1123024.AUII01000025_gene2129	9.191e-22	105.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,2IH0Y@201174|Actinobacteria,4E30J@85010|Pseudonocardiales	201174|Actinobacteria	FL	Metal binding domain of Ada	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1
SRD1_k127_7925520_0	330214.NIDE0324	9.547e-122	402.0	COG3191@1|root,COG3191@2|Bacteria	2|Bacteria	EQ	aminopeptidase activity	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
SRD1_k127_7925520_5	56110.Oscil6304_1264	8.024e-36	150.0	COG2385@1|root,COG2385@2|Bacteria,1G2FP@1117|Cyanobacteria,1H8UJ@1150|Oscillatoriales	1117|Cyanobacteria	D	PFAM Stage II sporulation protein	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
SRD1_k127_7925520_4	28042.GU90_10085	1.232e-38	164.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4DY4W@85010|Pseudonocardiales	201174|Actinobacteria	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRD1_k127_7925520_2	290397.Adeh_0738	1.53e-44	174.0	COG0122@1|root,COG0122@2|Bacteria,1P0FP@1224|Proteobacteria	1224|Proteobacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRD1_k127_7925520_1	1042877.GQS_10185	6.385e-96	325.0	COG1703@1|root,arCOG01226@2157|Archaea,2XUHG@28890|Euryarchaeota,242YC@183968|Thermococci	183968|Thermococci	E	GTPase activity	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRD1_k127_847983_0	635013.TherJR_0178	3.198e-190	608.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,2600Y@186807|Peptococcaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRD1_k127_885300_0	696281.Desru_1145	3.259e-120	394.0	COG4864@1|root,COG4864@2|Bacteria,1TPTD@1239|Firmicutes,24APU@186801|Clostridia,260UQ@186807|Peptococcaceae	186801|Clostridia	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
SRD1_k127_885300_1	644966.Tmar_2177	6.524e-65	241.0	COG1030@1|root,COG1030@2|Bacteria,1TR54@1239|Firmicutes,247N5@186801|Clostridia,3WDIF@538999|Clostridiales incertae sedis	186801|Clostridia	O	NfeD-like C-terminal, partner-binding	yqeZ	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
SRD1_k127_885300_2	240015.ACP_2390	1.413e-19	95.0	COG1610@1|root,COG1610@2|Bacteria,3Y4VF@57723|Acidobacteria,2JJJH@204432|Acidobacteriia	204432|Acidobacteriia	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRD1_k127_885300_3	1121422.AUMW01000027_gene441	9.071e-18	86.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
SRD1_k127_885590_1	742742.HMPREF9452_01828	2.137e-49	184.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4CU8J@84998|Coriobacteriia	84998|Coriobacteriia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	DegV,GARS_A,GARS_C,GARS_N
SRD1_k127_885590_0	311424.DhcVS_1196	1.929e-161	522.0	COG0034@1|root,COG0034@2|Bacteria,2G61T@200795|Chloroflexi,34CJ3@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
SRD1_k127_910394_6	702450.CUW_1903	9.478e-18	86.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,3VRKQ@526524|Erysipelotrichia	526524|Erysipelotrichia	J	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
SRD1_k127_910394_4	1121468.AUBR01000005_gene97	3.487e-64	237.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,24ANI@186801|Clostridia,42FW0@68295|Thermoanaerobacterales	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD1_k127_910394_5	1121468.AUBR01000012_gene2577	1.218e-31	139.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,42EPK@68295|Thermoanaerobacterales	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
SRD1_k127_910394_1	309801.trd_0778	6.57e-141	458.0	COG0057@1|root,COG0057@2|Bacteria,2G5MG@200795|Chloroflexi,27Y38@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRD1_k127_910394_2	696369.KI912183_gene1961	1.436e-120	406.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,2605P@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRD1_k127_910394_3	370438.PTH_2721	1.089e-64	239.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,260CH@186807|Peptococcaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRD1_k127_910394_0	207559.Dde_1757	2.598e-147	484.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2WJ66@28221|Deltaproteobacteria,2M93K@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
SRD1_k127_937002_3	1163409.UUA_01574	5.248e-26	113.0	COG2207@1|root,COG2207@2|Bacteria,1N8ZK@1224|Proteobacteria,1T6Z9@1236|Gammaproteobacteria,1X8G8@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRD1_k127_937002_5	278957.ABEA03000176_gene2841	3.146e-12	74.0	COG1999@1|root,COG1999@2|Bacteria,46W2T@74201|Verrucomicrobia,3K80B@414999|Opitutae	414999|Opitutae	S	Copper binding periplasmic protein CusF	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	CusF_Ec,SCO1-SenC
SRD1_k127_937002_4	1547437.LL06_01270	6.645e-16	88.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2UBUR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Protein conserved in bacteria	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
SRD1_k127_937002_1	547045.NEISICOT_02055	2.934e-32	137.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,2KQCS@206351|Neisseriales	206351|Neisseriales	S	SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRD1_k127_937002_0	450851.PHZ_c0831	2.61e-43	167.0	COG4977@1|root,COG4977@2|Bacteria,1PFG6@1224|Proteobacteria,2V7GC@28211|Alphaproteobacteria,2KJ6G@204458|Caulobacterales	204458|Caulobacterales	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRD1_k127_937002_2	1382356.JQMP01000004_gene119	4.451e-28	120.0	2E4KM@1|root,32ZFK@2|Bacteria,2GBAS@200795|Chloroflexi,27YJQ@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRD1_k127_937002_6	661478.OP10G_0763	2.185e-05	57.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRD1_k127_941091_2	935863.AWZR01000003_gene2845	1.811e-24	118.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1X7Y9@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyl transferases group 1	-	-	-	ko:K21001	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
SRD1_k127_941091_3	1089546.AQUI01000002_gene2058	2.296e-24	116.0	COG0438@1|root,COG0438@2|Bacteria,2GNR8@201174|Actinobacteria,408AD@622450|Actinopolysporales	201174|Actinobacteria	M	Glycosyl transferase 4-like	-	-	-	ko:K19424	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRD1_k127_941091_0	1173026.Glo7428_0892	1.263e-60	223.0	28IVI@1|root,2Z8TY@2|Bacteria,1G87H@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
SRD1_k127_941091_1	592015.HMPREF1705_00547	5.586e-31	132.0	COG0241@1|root,COG0241@2|Bacteria,3TB5N@508458|Synergistetes	508458|Synergistetes	E	1,7-bisphosphate phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_951954_2	1121334.KB911073_gene1941	5.509e-94	313.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,3WGA4@541000|Ruminococcaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRD1_k127_951954_3	383372.Rcas_1383	6.796e-47	186.0	COG2890@1|root,COG2890@2|Bacteria,2G6I8@200795|Chloroflexi,375AV@32061|Chloroflexia	32061|Chloroflexia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRD1_k127_951954_1	1278073.MYSTI_07371	2.5e-114	377.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,42YH3@68525|delta/epsilon subdivisions,2WU01@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Coproporphyrinogen III oxidase	hemF	-	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
SRD1_k127_951954_0	555079.Toce_2181	1.31e-232	731.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,42F21@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
SRD1_k127_976320_0	234267.Acid_2596	0.0	1043.0	COG4447@1|root,COG4447@2|Bacteria,3Y2SN@57723|Acidobacteria	57723|Acidobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRD1_k127_976320_4	1278073.MYSTI_06593	2.938e-123	417.0	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,437YB@68525|delta/epsilon subdivisions,2X387@28221|Deltaproteobacteria,2YVXR@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRD1_k127_976320_14	1149133.ppKF707_4725	1.395e-21	101.0	COG3108@1|root,COG3108@2|Bacteria,1QEUE@1224|Proteobacteria,1TBQS@1236|Gammaproteobacteria,1YIK8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF882)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_2
SRD1_k127_976320_18	1300345.LF41_1416	3.186e-10	66.0	2E5FW@1|root,3307K@2|Bacteria,1R3G8@1224|Proteobacteria,1T67F@1236|Gammaproteobacteria,1X8M9@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
SRD1_k127_976320_1	926560.KE387023_gene1973	4.286e-153	499.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1WIZK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	PFAM Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
SRD1_k127_976320_17	1122605.KB893626_gene2770	2.219e-13	75.0	2F60U@1|root,33YJ8@2|Bacteria,4P494@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRD1_k127_976320_8	1035308.AQYY01000001_gene1577	7.029e-94	319.0	COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,24CIW@186801|Clostridia	186801|Clostridia	E	hmm pf01447	-	-	3.4.24.28,3.4.24.29	ko:K01400,ko:K01401	ko01503,ko05150,map01503,map05150	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FTP,PPC,PepSY,Peptidase_M4,Peptidase_M4_C
SRD1_k127_976320_15	1121015.N789_06345	2.124e-18	100.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,1X4WG@135614|Xanthomonadales	135614|Xanthomonadales	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRD1_k127_976320_12	156889.Mmc1_2179	2.006e-26	122.0	COG1357@1|root,COG2931@1|root,COG3184@1|root,COG1357@2|Bacteria,COG2931@2|Bacteria,COG3184@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Collar,HemolysinCabind,Peptidase_M10_C
SRD1_k127_976320_16	1254432.SCE1572_45095	2.624e-16	94.0	COG1357@1|root,COG5351@1|root,COG1357@2|Bacteria,COG5351@2|Bacteria,1N7U9@1224|Proteobacteria,42RQA@68525|delta/epsilon subdivisions,2X63E@28221|Deltaproteobacteria	1224|Proteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2169)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2169,Pentapeptide,Pentapeptide_4
SRD1_k127_976320_11	251221.35211640	3.629e-35	155.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4825,PBP_dimer,Peptidase_M56,Transpeptidase
SRD1_k127_976320_10	251221.35213547	1.093e-35	139.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRD1_k127_976320_6	909613.UO65_1874	1.35e-108	366.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4DYYS@85010|Pseudonocardiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRD1_k127_976320_13	1232410.KI421424_gene1807	4.964e-23	102.0	2BWVJ@1|root,33YN1@2|Bacteria,1NXTC@1224|Proteobacteria,430BZ@68525|delta/epsilon subdivisions,2WVZK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_976320_2	1463856.JOHY01000032_gene2957	1.752e-144	472.0	COG4409@1|root,COG4409@2|Bacteria,2GN94@201174|Actinobacteria	201174|Actinobacteria	G	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
SRD1_k127_976320_5	272134.KB731324_gene3157	9.383e-115	401.0	COG5549@1|root,COG5549@2|Bacteria,1G2AK@1117|Cyanobacteria,1H6X4@1150|Oscillatoriales	1117|Cyanobacteria	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
SRD1_k127_976320_7	1122609.AUGT01000009_gene3341	1.263e-99	353.0	COG0665@1|root,COG0665@2|Bacteria,2I9WR@201174|Actinobacteria,4DRYR@85009|Propionibacteriales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRD1_k127_976320_3	247639.MGP2080_02481	1.301e-136	447.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1RYN7@1236|Gammaproteobacteria,1JBXZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
SRD1_k127_976320_9	321332.CYB_2124	2.535e-66	233.0	COG0834@1|root,COG0834@2|Bacteria,1GJVF@1117|Cyanobacteria,1H1U5@1129|Synechococcus	1117|Cyanobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
SRD1_k127_981393_5	932677.PAJ_2621	5.379e-50	183.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,3VYVB@53335|Pantoea	1236|Gammaproteobacteria	S	in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine	ygiD	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046566,GO:0051213,GO:0055114	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
SRD1_k127_981393_1	1267535.KB906767_gene5167	8.109e-76	261.0	COG0225@1|root,COG0225@2|Bacteria,3Y7DI@57723|Acidobacteria	57723|Acidobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRD1_k127_981393_0	330214.NIDE3604	2.152e-133	432.0	COG0435@1|root,COG0435@2|Bacteria	2|Bacteria	O	Glutathione S-transferase	yqjG	GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.5.7,2.5.1.18	ko:K00799,ko:K07393	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	iECW_1372.ECW_m3373,iWFL_1372.ECW_m3373	GST_C_2,GST_N_2
SRD1_k127_981393_9	42256.RradSPS_2003	0.0001022	51.0	COG4968@1|root,COG4968@2|Bacteria,2I4BD@201174|Actinobacteria,4CU66@84995|Rubrobacteria	84995|Rubrobacteria	NU	Cell motility and secretion Intracellular trafficking and secretion	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRD1_k127_981393_8	285514.JNWO01000006_gene1524	6.179e-13	77.0	COG2188@1|root,COG2188@2|Bacteria,2GKW8@201174|Actinobacteria	201174|Actinobacteria	K	gntR family	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRD1_k127_981393_6	596330.HMPREF0628_0256	1.602e-16	88.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia,22GGC@1570339|Peptoniphilaceae	186801|Clostridia	T	Response regulator receiver domain protein	cutR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_981393_3	471852.Tcur_3575	4.666e-60	218.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4EFT7@85012|Streptosporangiales	201174|Actinobacteria	C	Electron transfer flavoprotein domain	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRD1_k127_981393_2	1210045.ALNP01000037_gene2322	4.084e-67	240.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria	201174|Actinobacteria	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRD1_k127_981393_7	867845.KI911784_gene2462	2.122e-15	89.0	COG0457@1|root,COG0457@2|Bacteria,2GBDY@200795|Chloroflexi,375DC@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8
SRD1_k127_981393_4	378806.STAUR_6566	7.343e-53	199.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2YU20@29|Myxococcales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRD1_k127_982964_0	290317.Cpha266_1159	5.819e-60	215.0	COG2738@1|root,COG2738@2|Bacteria,1FEE1@1090|Chlorobi	1090|Chlorobi	S	PFAM peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
SRD1_k127_982964_1	445335.CBN_3268	1.241e-06	60.0	COG2378@1|root,COG2378@2|Bacteria,1TT23@1239|Firmicutes,248A8@186801|Clostridia,36E8C@31979|Clostridiaceae	186801|Clostridia	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
SRD1_k127_983012_1	1472716.KBK24_0112220	3.746e-11	66.0	2EFSS@1|root,339IS@2|Bacteria,1NHF5@1224|Proteobacteria,2WDD6@28216|Betaproteobacteria,1KA1W@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3311)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3311
SRD1_k127_983012_0	1047013.AQSP01000133_gene2109	5.319e-93	327.0	COG0591@1|root,COG0591@2|Bacteria,2NQV3@2323|unclassified Bacteria	2|Bacteria	E	Sodium:solute symporter family	yhjB	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
SRD1_k127_983012_2	1206739.BAGJ01000273_gene4012	6.922e-09	65.0	2CHCR@1|root,2ZT0Y@2|Bacteria,2HHZF@201174|Actinobacteria,4G1VY@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_990289_0	234267.Acid_5837	6.328e-167	535.0	COG1201@1|root,COG1201@2|Bacteria,3Y348@57723|Acidobacteria	57723|Acidobacteria	L	DEAD DEAH box	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRD1_k127_990289_6	1122179.KB890431_gene4187	1.061e-06	57.0	2EHC3@1|root,33B3Y@2|Bacteria,4NZPQ@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
SRD1_k127_990289_5	1380370.JIBA01000016_gene819	2.641e-07	61.0	COG2755@1|root,COG2755@2|Bacteria,2HXHN@201174|Actinobacteria,4FGWU@85021|Intrasporangiaceae	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRD1_k127_990289_1	1128421.JAGA01000002_gene189	1.659e-77	275.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2NR1B@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	yhcY	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
SRD1_k127_990289_4	266117.Rxyl_2613	9.377e-46	175.0	COG2197@1|root,COG2197@2|Bacteria,2GMUG@201174|Actinobacteria,4CTCH@84995|Rubrobacteria	84995|Rubrobacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD1_k127_990289_3	448385.sce4978	2.051e-53	198.0	COG0300@1|root,COG0300@2|Bacteria,1QUNR@1224|Proteobacteria,43CVE@68525|delta/epsilon subdivisions,2X83C@28221|Deltaproteobacteria,2Z3K2@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD1_k127_990289_2	1121377.KB906405_gene135	1.661e-61	226.0	COG0809@1|root,COG0809@2|Bacteria,1WJW8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRD1_k127_999746_2	1128421.JAGA01000004_gene2675	2.01e-104	351.0	COG0372@1|root,COG0372@2|Bacteria,2NP9P@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRD1_k127_999746_3	215803.DB30_2965	2.775e-88	305.0	COG0665@1|root,COG0665@2|Bacteria,1MU7M@1224|Proteobacteria,42P85@68525|delta/epsilon subdivisions,2WSYY@28221|Deltaproteobacteria,2YVCG@29|Myxococcales	28221|Deltaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRD1_k127_999746_6	485913.Krac_11897	7.579e-68	251.0	COG0707@1|root,COG0707@2|Bacteria,2G6CA@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase 28 domain	-	-	2.4.1.46	ko:K03715	ko00561,ko01100,map00561,map01100	-	R02691	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
SRD1_k127_999746_7	1507.HMPREF0262_01983	7.126e-52	196.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,36ESA@31979|Clostridiaceae	186801|Clostridia	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRD1_k127_999746_4	1121378.KB899737_gene3941	6.799e-86	294.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	MA20_01210	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRD1_k127_999746_5	1510531.JQJJ01000012_gene1758	2.681e-82	285.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQJC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRD1_k127_999746_8	1041159.AZUW01000006_gene1833	1.032e-29	124.0	COG0073@1|root,COG0073@2|Bacteria,1RGU7@1224|Proteobacteria,2U9AH@28211|Alphaproteobacteria,4BEPC@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	tRNA-binding protein	csaA	GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
SRD1_k127_999746_0	867903.ThesuDRAFT_01180	0.0	1148.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia	186801|Clostridia	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRD1_k127_999746_1	485913.Krac_11709	1.624e-224	704.0	COG0473@1|root,COG0473@2|Bacteria,2G7RB@200795|Chloroflexi	200795|Chloroflexi	C	Isocitrate/isopropylmalate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
SRD1_k127_999746_9	36809.MAB_3105c	2.284e-27	124.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,233RW@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the peptidase M16 family	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
## 2177 queries scanned
## Total time (seconds): 170.410227060318
## Rate: 12.78 q/s