## Wed Feb 18 17:32:12 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/SRD1_bin.30.fa -m mmseqs --output SRD1_bin.30 --output_dir /data/result/bins/wyx/eggqs50+/SRD1_bin.30 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRD1_k127_1008073_1	640081.Dsui_2059	3.073e-52	196.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VM4B@28216|Betaproteobacteria,2KZ2Q@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD1_k127_1008073_0	1206735.BAGG01000046_gene1971	1.563e-76	271.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2GKSQ@201174|Actinobacteria,4FW36@85025|Nocardiaceae	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	livF	-	-	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRD1_k127_1032541_1	926569.ANT_14230	7.852e-58	203.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRD1_k127_1032541_3	85643.Tmz1t_3374	5.895e-24	104.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRD1_k127_1032541_2	1343740.M271_18265	9.346e-52	205.0	COG4585@1|root,COG4585@2|Bacteria,2GKRM@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HisKA_3
SRD1_k127_1032541_0	485913.Krac_5377	4.833e-76	267.0	COG2197@1|root,COG2197@2|Bacteria,2G6K1@200795|Chloroflexi	2|Bacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRD1_k127_1032541_4	1380393.JHVP01000009_gene1386	4.906e-23	102.0	COG0477@1|root,COG0477@2|Bacteria,2I48M@201174|Actinobacteria,4EXF3@85013|Frankiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRD1_k127_1032833_5	309803.CTN_0519	2.888e-48	175.0	COG0495@1|root,COG0495@2|Bacteria,2GC3Z@200918|Thermotogae	200918|Thermotogae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRD1_k127_1032833_4	266117.Rxyl_0138	1.899e-49	188.0	COG0697@1|root,COG0697@2|Bacteria,2I8X5@201174|Actinobacteria	201174|Actinobacteria	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRD1_k127_1032833_2	589924.Ferp_0691	1.705e-53	192.0	COG0537@1|root,arCOG00419@2157|Archaea,2XWGT@28890|Euryarchaeota,2466N@183980|Archaeoglobi	183980|Archaeoglobi	F	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRD1_k127_1032833_1	357808.RoseRS_1950	1.495e-96	335.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi,375CQ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRD1_k127_1032833_0	562970.Btus_1728	2.939e-143	464.0	COG1960@1|root,COG1960@2|Bacteria,1TSN3@1239|Firmicutes,4HB0T@91061|Bacilli,278X4@186823|Alicyclobacillaceae	91061|Bacilli	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249,ko:K11731	ko00071,ko00280,ko00281,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00281,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754,R08089	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246,RC01893	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_1032833_3	1095772.CAHH01000028_gene2566	1.485e-52	192.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria	201174|Actinobacteria	J	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRD1_k127_1032833_6	521098.Aaci_1010	2.805e-34	144.0	COG1502@1|root,COG1502@2|Bacteria,1UXX9@1239|Firmicutes	1239|Firmicutes	I	Phosphatidylserine phosphatidylglycerophosphate cardiolipin	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRD1_k127_1032833_7	1249627.D779_3546	6.371e-05	46.0	COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,1RQES@1236|Gammaproteobacteria,1WXQ1@135613|Chromatiales	135613|Chromatiales	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRD1_k127_1035812_1	228410.NE2041	2.59e-28	127.0	2CCJR@1|root,2ZCU4@2|Bacteria,1RC7F@1224|Proteobacteria,2W4MN@28216|Betaproteobacteria,3720D@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1035812_0	709797.CSIRO_1431	6.373e-96	329.0	COG0683@1|root,COG0683@2|Bacteria,1MV1Z@1224|Proteobacteria,2TRTD@28211|Alphaproteobacteria,3JRR8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRD1_k127_1036151_0	656024.FsymDg_3626	1.218e-300	929.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4ERMR@85013|Frankiales	201174|Actinobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRD1_k127_1036704_0	864702.OsccyDRAFT_1593	2.958e-70	244.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD1_k127_1036704_8	1449347.JQLN01000005_gene3531	1.901e-16	86.0	COG3305@1|root,COG3305@2|Bacteria,2GNU5@201174|Actinobacteria,2M2AM@2063|Kitasatospora	201174|Actinobacteria	S	Predicted membrane protein (DUF2127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2127
SRD1_k127_1036704_5	255470.cbdbA34	2.611e-29	124.0	COG0589@1|root,COG0589@2|Bacteria,2G7D7@200795|Chloroflexi,34DAT@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRD1_k127_1036704_1	485913.Krac_8326	9.099e-39	150.0	COG0569@1|root,COG0569@2|Bacteria,2G71A@200795|Chloroflexi	200795|Chloroflexi	C	PFAM TrkA-N domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
SRD1_k127_1036704_2	485913.Krac_8327	4.662e-38	148.0	COG0569@1|root,COG0569@2|Bacteria,2G6J8@200795|Chloroflexi	200795|Chloroflexi	C	PFAM TrkA-N domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRD1_k127_1036704_9	1459636.NTE_03059	2.344e-13	70.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1036704_3	1379698.RBG1_1C00001G0667	7.616e-36	145.0	COG2110@1|root,COG2110@2|Bacteria,2NPPR@2323|unclassified Bacteria	2|Bacteria	S	Appr-1'-p processing enzyme	tfaE	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Caudo_TAP,Macro
SRD1_k127_1036704_6	1144275.COCOR_04284	7.962e-29	127.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,2YU0F@29|Myxococcales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
SRD1_k127_1036704_4	1009370.ALO_05268	2.24e-33	138.0	COG0613@1|root,COG0613@2|Bacteria,1VCKE@1239|Firmicutes,4H57V@909932|Negativicutes	909932|Negativicutes	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
SRD1_k127_1036704_10	404589.Anae109_1338	9.58e-06	53.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	1.17.1.9	ko:K00125,ko:K03646	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000,ko02000	2.C.1.2	-	-	Fer4,Fer4_17,Fer4_22,Fer4_8,FrhB_FdhB_C
SRD1_k127_1036704_7	716541.ECL_03533	3.843e-28	121.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RUEK@1236|Gammaproteobacteria,3X0N1@547|Enterobacter	1236|Gammaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpA	GO:0000166,GO:0003674,GO:0003824,GO:0004368,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006072,GO:0006091,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016901,GO:0019637,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046168,GO:0046434,GO:0048037,GO:0050660,GO:0050662,GO:0052646,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901136,GO:1901265,GO:1901363,GO:1901575	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	iSDY_1059.SDY_2436	DAO,Fer2_BFD
SRD1_k127_1043290_3	1246995.AFR_10190	3.175e-76	261.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,4DBVJ@85008|Micromonosporales	201174|Actinobacteria	K	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_1043290_2	869210.Marky_0813	2.508e-88	304.0	COG0111@1|root,COG0111@2|Bacteria,1WI3I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh_C
SRD1_k127_1043290_5	338969.Rfer_0357	4.277e-42	167.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VQ0S@28216|Betaproteobacteria,4ABCM@80864|Comamonadaceae	28216|Betaproteobacteria	P	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
SRD1_k127_1043290_4	358681.BBR47_44360	4.102e-45	166.0	COG0662@1|root,COG0662@2|Bacteria,1V7K2@1239|Firmicutes,4HN60@91061|Bacilli,26WT8@186822|Paenibacillaceae	91061|Bacilli	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD1_k127_1043290_7	234267.Acid_2832	1.207e-26	112.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRD1_k127_1043290_8	485913.Krac_6053	9.754e-22	100.0	2BVHN@1|root,32SWN@2|Bacteria,2G8ZV@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRD1_k127_1043290_6	446470.Snas_3937	9.076e-31	132.0	COG1309@1|root,COG1309@2|Bacteria,2IR4P@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD1_k127_1043290_0	929562.Emtol_4071	6.612e-125	428.0	COG2170@1|root,COG2170@2|Bacteria,4NFFP@976|Bacteroidetes,47KG2@768503|Cytophagia	976|Bacteroidetes	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRD1_k127_1043290_1	1521187.JPIM01000025_gene1118	5.455e-96	327.0	COG2308@1|root,COG2308@2|Bacteria,2G7ZB@200795|Chloroflexi,3754D@32061|Chloroflexia	32061|Chloroflexia	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SRD1_k127_1052874_0	1127134.NOCYR_1168	2.202e-51	188.0	COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,4FUW7@85025|Nocardiaceae	201174|Actinobacteria	Q	Isochorismatase family	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SRD1_k127_1052874_4	909663.KI867150_gene1557	3.681e-21	98.0	COG3360@1|root,COG3360@2|Bacteria,1Q2I5@1224|Proteobacteria,42VRR@68525|delta/epsilon subdivisions,2WRD2@28221|Deltaproteobacteria,2MS5T@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRD1_k127_1052874_1	1206743.BAGM01000210_gene423	2.31e-49	184.0	COG3832@1|root,COG3832@2|Bacteria,2IN9D@201174|Actinobacteria,4G113@85025|Nocardiaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRD1_k127_1052874_2	37919.EP51_30005	2.089e-47	179.0	COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria,4G18G@85025|Nocardiaceae	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SRD1_k127_1052874_3	1297742.A176_04053	5.506e-37	141.0	COG0640@1|root,COG0640@2|Bacteria,1N1QR@1224|Proteobacteria,43DTX@68525|delta/epsilon subdivisions,2WYV0@28221|Deltaproteobacteria,2Z0PR@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
SRD1_k127_1059232_0	1283299.AUKG01000001_gene2768	3.863e-167	551.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CS0R@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRD1_k127_1059232_1	1382306.JNIM01000001_gene1358	8.932e-39	156.0	COG0215@1|root,COG1216@1|root,COG0215@2|Bacteria,COG1216@2|Bacteria,2G5Z0@200795|Chloroflexi	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRD1_k127_1059232_2	240015.ACP_0765	1.648e-19	89.0	COG2025@1|root,COG2025@2|Bacteria,3Y3JE@57723|Acidobacteria,2JM9U@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRD1_k127_1083920_1	1122939.ATUD01000017_gene3992	1.697e-68	234.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4CPJM@84995|Rubrobacteria	84995|Rubrobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRD1_k127_1083920_4	1120949.KB903304_gene7006	3.393e-33	137.0	COG0265@1|root,COG0265@2|Bacteria,2IJ6Q@201174|Actinobacteria,4DDWI@85008|Micromonosporales	201174|Actinobacteria	O	peptidase S1 and S6, chymotrypsin Hap	hhoB	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Trypsin_2
SRD1_k127_1083920_7	1463920.JOGB01000031_gene6041	9.166e-15	87.0	2F0BY@1|root,33TF4@2|Bacteria,2ICQW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1083920_3	1382356.JQMP01000003_gene2307	1.58e-34	143.0	COG1842@1|root,COG1842@2|Bacteria,2G8QB@200795|Chloroflexi,27Y1A@189775|Thermomicrobia	189775|Thermomicrobia	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRD1_k127_1083920_2	1382356.JQMP01000003_gene2307	2.077e-51	191.0	COG1842@1|root,COG1842@2|Bacteria,2G8QB@200795|Chloroflexi,27Y1A@189775|Thermomicrobia	189775|Thermomicrobia	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRD1_k127_1083920_0	450851.PHZ_c1594	1.696e-88	297.0	COG1878@1|root,COG1878@2|Bacteria,1R8IH@1224|Proteobacteria,2U9RH@28211|Alphaproteobacteria,2KIQF@204458|Caulobacterales	204458|Caulobacterales	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRD1_k127_1083920_6	1121946.AUAX01000030_gene1290	1.87e-20	101.0	COG2852@1|root,COG2852@2|Bacteria,2GN40@201174|Actinobacteria,4DDX1@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRD1_k127_1083920_5	479434.Sthe_1091	4.976e-25	106.0	COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi,27XZS@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRD1_k127_1107731_13	1051632.TPY_0321	9.355e-26	106.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WCCR@538999|Clostridiales incertae sedis	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRD1_k127_1107731_0	243231.GSU2860	5.315e-290	905.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRD1_k127_1107731_11	867903.ThesuDRAFT_00555	3.806e-54	202.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,3WCGJ@538999|Clostridiales incertae sedis	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRD1_k127_1107731_10	326424.FRAAL1076	4.859e-56	208.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4ESMM@85013|Frankiales	201174|Actinobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRD1_k127_1107731_12	345341.KUTG_09006	8.812e-28	119.0	COG1971@1|root,COG1971@2|Bacteria	2|Bacteria	P	manganese ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
SRD1_k127_1107731_2	926550.CLDAP_11110	1.074e-126	415.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRD1_k127_1107731_4	1121106.JQKB01000005_gene2128	6.603e-113	374.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,2JVKW@204441|Rhodospirillales	204441|Rhodospirillales	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
SRD1_k127_1107731_5	255470.cbdbA1037	1.872e-92	312.0	COG1173@1|root,COG1173@2|Bacteria,2G9WH@200795|Chloroflexi,34DKE@301297|Dehalococcoidia	301297|Dehalococcoidia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRD1_k127_1107731_6	255470.cbdbA1038	8.205e-89	304.0	COG0601@1|root,COG0601@2|Bacteria,2G9WT@200795|Chloroflexi,34DMG@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
SRD1_k127_1107731_9	1321778.HMPREF1982_04442	2.927e-58	224.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,2682G@186813|unclassified Clostridiales	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRD1_k127_1107731_1	1382306.JNIM01000001_gene1271	3.446e-129	422.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRD1_k127_1107731_3	489825.LYNGBM3L_32450	5.55e-120	395.0	COG0444@1|root,COG0444@2|Bacteria,1G1NU@1117|Cyanobacteria,1HA9I@1150|Oscillatoriales	1117|Cyanobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRD1_k127_1107731_7	1286171.EAL2_c07090	3.82e-73	256.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,25WAU@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, permease protein	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRD1_k127_1107731_8	867903.ThesuDRAFT_02279	8.861e-70	247.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3WD0N@538999|Clostridiales incertae sedis	186801|Clostridia	U	ABC transporter (Permease)	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
SRD1_k127_1107949_1	1242864.D187_004008	2.048e-32	136.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1RAHZ@1224|Proteobacteria,42UGY@68525|delta/epsilon subdivisions,2WQPI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,GAF_2,Guanylate_cyc
SRD1_k127_1107949_0	590998.Celf_1107	3.346e-71	248.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4F0FB@85016|Cellulomonadaceae	201174|Actinobacteria	L	TIGRFAM ATP-dependent DNA helicase PcrA	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRD1_k127_1110281_3	42256.RradSPS_0217	3.415e-11	66.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CPCQ@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRD1_k127_1110281_1	1521187.JPIM01000013_gene2756	1.161e-36	144.0	COG1666@1|root,COG1666@2|Bacteria,2G6TD@200795|Chloroflexi,375J1@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
SRD1_k127_1110281_0	665571.STHERM_c01300	4.474e-51	190.0	COG0106@1|root,COG0106@2|Bacteria,2J8GX@203691|Spirochaetes	203691|Spirochaetes	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRD1_k127_1110281_2	1380347.JNII01000008_gene4408	2.054e-29	121.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria,4EUFI@85013|Frankiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD1_k127_1113546_3	351607.Acel_0595	5.529e-35	141.0	COG1873@1|root,COG2239@1|root,COG1873@2|Bacteria,COG2239@2|Bacteria,2GMMK@201174|Actinobacteria,4ERJN@85013|Frankiales	201174|Actinobacteria	P	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
SRD1_k127_1113546_0	1111479.AXAR01000008_gene2292	1.678e-199	635.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HE2B@91061|Bacilli	91061|Bacilli	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
SRD1_k127_1113546_1	1382306.JNIM01000001_gene253	1.26e-51	196.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRD1_k127_1113546_4	485913.Krac_12334	3.661e-12	79.0	COG0823@1|root,COG0823@2|Bacteria,2G9NG@200795|Chloroflexi	200795|Chloroflexi	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRD1_k127_1113546_2	195250.CM001776_gene1785	1.768e-35	147.0	COG0744@1|root,COG0744@2|Bacteria,1G28H@1117|Cyanobacteria,1H47Y@1129|Synechococcus	1117|Cyanobacteria	M	Transglycosylase	ponA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRD1_k127_1123074_5	525904.Tter_0915	2.833e-29	126.0	COG0149@1|root,COG0149@2|Bacteria,2NP24@2323|unclassified Bacteria	2|Bacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009758,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016854,GO:0016857,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	2.7.2.3,5.1.3.39,5.3.1.1,5.3.1.33	ko:K00927,ko:K01803,ko:K20905,ko:K21910	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265,iJN746.PP_4715	TIM
SRD1_k127_1123074_2	264732.Moth_0263	8.711e-123	407.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,42F8F@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRD1_k127_1123074_1	1382356.JQMP01000003_gene2505	2.134e-129	424.0	COG0057@1|root,COG0057@2|Bacteria,2G5MG@200795|Chloroflexi,27Y38@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRD1_k127_1123074_3	1262915.BN574_00327	1.782e-44	174.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4H222@909932|Negativicutes	909932|Negativicutes	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
SRD1_k127_1123074_0	326427.Cagg_2096	2.083e-142	461.0	COG0022@1|root,COG0022@2|Bacteria,2G5JU@200795|Chloroflexi,374SG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Transketolase central region	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRD1_k127_1123074_4	1121377.KB906409_gene862	5.938e-42	164.0	COG0006@1|root,COG0006@2|Bacteria,1WIXQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRD1_k127_1124299_7	526225.Gobs_1652	2.205e-43	166.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4EVYT@85013|Frankiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD1_k127_1124299_5	1128421.JAGA01000001_gene2136	5.204e-58	218.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRD1_k127_1124299_3	1463820.JOGW01000001_gene5517	7.867e-87	295.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria	201174|Actinobacteria	G	polyphosphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRD1_k127_1124299_2	106370.Francci3_3863	7.204e-95	320.0	COG0265@1|root,COG0265@2|Bacteria,2GNZT@201174|Actinobacteria,4EUA7@85013|Frankiales	201174|Actinobacteria	O	peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRD1_k127_1124299_0	357808.RoseRS_2761	2.282e-135	443.0	COG1020@1|root,COG1020@2|Bacteria,2G7PI@200795|Chloroflexi	200795|Chloroflexi	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRD1_k127_1124299_1	1394178.AWOO02000023_gene5544	5.668e-104	361.0	COG3842@1|root,COG3842@2|Bacteria,2H2JF@201174|Actinobacteria,4EH68@85012|Streptosporangiales	201174|Actinobacteria	P	TOBE domain	modC	-	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
SRD1_k127_1124299_4	1121924.ATWH01000003_gene1410	4.768e-70	248.0	COG4149@1|root,COG4149@2|Bacteria,2GJFB@201174|Actinobacteria,4FM7M@85023|Microbacteriaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	modB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE
SRD1_k127_1124299_6	258533.BN977_01876	5.491e-52	192.0	COG0725@1|root,COG0725@2|Bacteria,2GMPF@201174|Actinobacteria,234BP@1762|Mycobacteriaceae	201174|Actinobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRD1_k127_1125872_9	1179226.AJXO01000003_gene1617	3.51e-27	114.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,4GXB7@90964|Staphylococcaceae	91061|Bacilli	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRD1_k127_1125872_3	497964.CfE428DRAFT_0398	1.629e-56	215.0	COG5483@1|root,COG5483@2|Bacteria,46TB0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRD1_k127_1125872_10	469383.Cwoe_5806	3.824e-18	91.0	COG1595@1|root,COG1595@2|Bacteria,2HY6G@201174|Actinobacteria,4CQBA@84995|Rubrobacteria	84995|Rubrobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_1125872_6	1128421.JAGA01000002_gene101	3.544e-47	179.0	COG0584@1|root,COG0584@2|Bacteria,2NPNS@2323|unclassified Bacteria	2|Bacteria	C	PFAM Glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRD1_k127_1125872_0	1382306.JNIM01000001_gene1826	2.437e-189	606.0	COG1239@1|root,COG1239@2|Bacteria,2G5WJ@200795|Chloroflexi	200795|Chloroflexi	H	introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX	-	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
SRD1_k127_1125872_12	586416.GZ22_14485	0.0001022	51.0	COG2318@1|root,COG2318@2|Bacteria,1V2BI@1239|Firmicutes,4HF8B@91061|Bacilli	91061|Bacilli	S	Belongs to the metal hydrolase YfiT family	yfiT	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRD1_k127_1125872_5	1382356.JQMP01000003_gene2352	3.933e-48	179.0	COG1673@1|root,COG1673@2|Bacteria,2G9JU@200795|Chloroflexi,27Y95@189775|Thermomicrobia	189775|Thermomicrobia	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
SRD1_k127_1125872_7	1267535.KB906767_gene2770	1.238e-41	161.0	COG2898@1|root,COG2898@2|Bacteria,3Y4M0@57723|Acidobacteria,2JJ8Z@204432|Acidobacteriia	204432|Acidobacteriia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1125872_11	1121127.JAFA01000017_gene6283	7.049e-10	66.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VTRN@28216|Betaproteobacteria,1K356@119060|Burkholderiaceae	28216|Betaproteobacteria	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_1125872_8	1869.MB27_21195	1.187e-36	152.0	COG5662@1|root,COG5662@2|Bacteria,2GN1B@201174|Actinobacteria,4DBXN@85008|Micromonosporales	201174|Actinobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1125872_1	309801.trd_1503	1.722e-87	299.0	COG1131@1|root,COG1131@2|Bacteria,2G69S@200795|Chloroflexi,27XTG@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_1125872_2	1380393.JHVP01000005_gene3764	3.832e-58	212.0	COG1277@1|root,COG1277@2|Bacteria,2GKW6@201174|Actinobacteria,4ERMU@85013|Frankiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRD1_k127_1125872_4	1382306.JNIM01000001_gene3513	5.18e-50	180.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRD1_k127_1131840_2	1449346.JQMO01000002_gene689	1.42e-116	387.0	COG2072@1|root,COG2072@2|Bacteria,2GM3S@201174|Actinobacteria,2M590@2063|Kitasatospora	201174|Actinobacteria	P	Flavin-binding monooxygenase-like	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRD1_k127_1131840_3	1232410.KI421413_gene842	6.278e-90	314.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,43SZM@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRD1_k127_1131840_5	1122222.AXWR01000004_gene1784	2.909e-08	63.0	COG1276@1|root,COG1276@2|Bacteria,1WN6J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Copper resistance protein D	-	-	-	ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	CopD
SRD1_k127_1131840_1	644283.Micau_5370	1.035e-167	549.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DACA@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter related	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRD1_k127_1131840_0	1120950.KB892773_gene1095	2.363e-220	700.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DPXV@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRD1_k127_1131840_4	1121946.AUAX01000010_gene3771	3.86e-16	89.0	COG0454@1|root,COG0456@2|Bacteria,2IEMU@201174|Actinobacteria,4DEQ4@85008|Micromonosporales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD1_k127_1131840_7	999423.HMPREF9161_00609	0.0006033	49.0	COG0839@1|root,COG0839@2|Bacteria,1VAQI@1239|Firmicutes,4H4S3@909932|Negativicutes	909932|Negativicutes	C	NADH-ubiquinone plastoquinone oxidoreductase chain 6	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRD1_k127_1131840_6	882082.SaccyDRAFT_4044	6.5e-05	56.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,2GIT4@201174|Actinobacteria,4DZ06@85010|Pseudonocardiales	201174|Actinobacteria	CP	NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	-	-	-	ko:K05565,ko:K14086	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,NADHdh,Proton_antipo_M,Proton_antipo_N
SRD1_k127_1132297_5	697281.Mahau_2583	2.971e-29	118.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,42EY9@68295|Thermoanaerobacterales	186801|Clostridia	M	TIGRFAM UTP--glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRD1_k127_1132297_8	1121430.JMLG01000004_gene950	5.269e-19	93.0	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,2622Z@186807|Peptococcaceae	186801|Clostridia	S	THIoesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
SRD1_k127_1132297_12	42256.RradSPS_0047	2.375e-08	66.0	2DFV5@1|root,2ZT9W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1132297_9	1136417.AZWE01000004_gene4416	5.165e-14	74.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,4DF46@85008|Micromonosporales	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRD1_k127_1132297_11	1123072.AUDH01000001_gene2877	1.04e-13	82.0	COG0451@1|root,COG0451@2|Bacteria,1P603@1224|Proteobacteria,2U9VR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRD1_k127_1132297_7	1382306.JNIM01000001_gene4168	1.34e-21	105.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRD1_k127_1132297_4	1450694.BTS2_2929	5.864e-40	160.0	COG2267@1|root,COG2267@2|Bacteria,1TP59@1239|Firmicutes,4HBHV@91061|Bacilli,1ZSJG@1386|Bacillus	91061|Bacilli	I	Ndr family	yugF	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRD1_k127_1132297_10	485913.Krac_2293	5.185e-14	81.0	COG3340@1|root,COG3340@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRD1_k127_1132297_0	644966.Tmar_0077	2.754e-119	399.0	COG0008@1|root,COG1384@1|root,COG0008@2|Bacteria,COG1384@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3WCIN@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRD1_k127_1132297_6	324602.Caur_1344	6.861e-27	120.0	COG0682@1|root,COG0682@2|Bacteria,2G6QJ@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRD1_k127_1132297_3	1210884.HG799465_gene11340	5.92e-46	175.0	COG1801@1|root,COG1801@2|Bacteria,2IYWM@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRD1_k127_1132297_1	331113.SNE_A18180	2.464e-88	303.0	COG0820@1|root,COG0820@2|Bacteria,2JFG3@204428|Chlamydiae	204428|Chlamydiae	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN2	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
SRD1_k127_1132297_2	28444.JODQ01000014_gene6814	1.64e-54	202.0	COG0491@1|root,COG0491@2|Bacteria,2GKP9@201174|Actinobacteria,4EHC0@85012|Streptosporangiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	pksB_1	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRD1_k127_1149418_0	1206720.BAFQ01000147_gene3763	3.724e-66	230.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,4FVWD@85025|Nocardiaceae	201174|Actinobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD_5
SRD1_k127_1149418_2	196162.Noca_4890	3.996e-34	139.0	COG0425@1|root,COG0425@2|Bacteria,2GSNH@201174|Actinobacteria	201174|Actinobacteria	O	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRD1_k127_1149418_1	196162.Noca_4889	7.637e-50	183.0	COG2044@1|root,COG2044@2|Bacteria,2IHT6@201174|Actinobacteria	2|Bacteria	S	DsrE/DsrF-like family	-	-	-	ko:K06039,ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE
SRD1_k127_1150376_10	1123242.JH636435_gene1411	3.753e-13	70.0	COG2154@1|root,COG2154@2|Bacteria,2J0CT@203682|Planctomycetes	203682|Planctomycetes	H	PFAM Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRD1_k127_1150376_0	1449976.KALB_3698	2.706e-207	665.0	COG1132@1|root,COG1132@2|Bacteria,2GJYK@201174|Actinobacteria,4DZ3N@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRD1_k127_1150376_7	211114.JOEF01000002_gene4458	1.781e-24	107.0	28M3Q@1|root,2ZAHT@2|Bacteria,2GM5B@201174|Actinobacteria,4E09Q@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1150376_4	479434.Sthe_3033	3.015e-52	189.0	COG0500@1|root,COG2226@2|Bacteria,2G8IB@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRD1_k127_1150376_11	1384056.N787_03600	5.398e-09	60.0	COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,1SCD4@1236|Gammaproteobacteria,1X8UE@135614|Xanthomonadales	135614|Xanthomonadales	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRD1_k127_1150376_6	1380390.JIAT01000014_gene6196	7.597e-38	144.0	COG3461@1|root,COG3461@2|Bacteria,2GZN9@201174|Actinobacteria,4CSVG@84995|Rubrobacteria	84995|Rubrobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1150376_2	1128421.JAGA01000001_gene2191	1.767e-69	259.0	COG0400@1|root,COG0400@2|Bacteria,2NRU7@2323|unclassified Bacteria	2|Bacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999,ko:K15975	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,Glyoxalase
SRD1_k127_1150376_3	42256.RradSPS_1006	6.526e-68	243.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CSII@84995|Rubrobacteria	84995|Rubrobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRD1_k127_1150376_1	373994.Riv7116_4435	1.85e-119	437.0	COG2304@1|root,COG3209@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,1GPZZ@1117|Cyanobacteria,1HJUW@1161|Nostocales	1117|Cyanobacteria	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,VWA
SRD1_k127_1150376_8	1382306.JNIM01000001_gene1513	8.426e-22	104.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3,GNAT_acetyltran
SRD1_k127_1150376_5	1298863.AUEP01000008_gene1241	3.138e-44	170.0	29ZNQ@1|root,30MP9@2|Bacteria,2IJUR@201174|Actinobacteria,4DUE8@85009|Propionibacteriales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRD1_k127_1162634_0	292459.STH1342	1.58e-88	302.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRD1_k127_1162634_5	1382306.JNIM01000001_gene4145	1.538e-44	168.0	COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi	200795|Chloroflexi	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRD1_k127_1162634_2	713586.KB900536_gene2229	9.465e-68	241.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1WWQE@135613|Chromatiales	135613|Chromatiales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRD1_k127_1162634_3	1499685.CCFJ01000043_gene2625	5.762e-56	200.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,1ZFJ0@1386|Bacillus	91061|Bacilli	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRD1_k127_1162634_4	640511.BC1002_3912	1.252e-54	194.0	COG0346@1|root,COG0346@2|Bacteria,1RIQG@1224|Proteobacteria,2W46B@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1162634_1	1382306.JNIM01000001_gene316	1.882e-69	246.0	COG0208@1|root,COG0208@2|Bacteria	2|Bacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
SRD1_k127_1196423_3	1380390.JIAT01000011_gene2578	4.55e-49	179.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
SRD1_k127_1196423_0	663932.KB902575_gene1894	3.721e-137	454.0	COG0687@1|root,COG0687@2|Bacteria,1NKD7@1224|Proteobacteria,2TYST@28211|Alphaproteobacteria,2JR9A@204441|Rhodospirillales	204441|Rhodospirillales	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
SRD1_k127_1196423_1	1304275.C41B8_09936	6.461e-106	351.0	COG1176@1|root,COG1176@2|Bacteria,1NU6V@1224|Proteobacteria,1RZ7V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC transporter (Permease	ydcU	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	iEcSMS35_1347.EcSMS35_1732	BPD_transp_1
SRD1_k127_1196423_2	1304275.C41B8_09931	2.556e-92	311.0	COG1177@1|root,COG1177@2|Bacteria,1N3TB@1224|Proteobacteria,1RP67@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC transporter (permease)	ydcV	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	iEC55989_1330.EC55989_1575,iECIAI1_1343.ECIAI1_1439,iECO111_1330.ECO111_1832,iECO26_1355.ECO26_2042,iECW_1372.ECW_m1571,iECs_1301.ECs2047,iEKO11_1354.EKO11_2376,iUMNK88_1353.UMNK88_1846,iWFL_1372.ECW_m1571,iZ_1308.Z2276,ic_1306.c1867	BPD_transp_1
SRD1_k127_1196423_4	1304275.C41B8_09941	4.127e-17	91.0	COG0687@1|root,COG0687@2|Bacteria,1NKD7@1224|Proteobacteria,1RQPF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Spermidine putrescine ABC transporter substrate-binding protein	ydcS	GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	iECNA114_1301.ECNA114_1576,iECSF_1327.ECSF_1364,iEcHS_1320.EcHS_A1524	SBP_bac_8
SRD1_k127_1219601_0	1120936.KB907211_gene456	1.59e-163	529.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4EFX9@85012|Streptosporangiales	201174|Actinobacteria	P	Nitrite and sulphite reductase 4Fe-4S domain	sir	GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016002,GO:0016053,GO:0016491,GO:0016667,GO:0016673,GO:0019344,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRD1_k127_1219601_2	1122138.AQUZ01000081_gene4845	1.42e-10	68.0	2E36U@1|root,32Y6I@2|Bacteria,2IM2G@201174|Actinobacteria,4DRR8@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1416)	sseC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1416
SRD1_k127_1219601_1	561175.KB894093_gene3340	5.556e-96	317.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria,4EG2F@85012|Streptosporangiales	201174|Actinobacteria	P	Rhodanese Homology Domain	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRD1_k127_1227341_1	485913.Krac_11550	2.122e-75	271.0	COG1814@1|root,COG1814@2|Bacteria,2G7AE@200795|Chloroflexi	200795|Chloroflexi	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRD1_k127_1227341_4	525909.Afer_1115	6.101e-12	72.0	2BM3X@1|root,32FM8@2|Bacteria,2HH03@201174|Actinobacteria,4CP0F@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1227341_3	42256.RradSPS_1660	1.041e-52	193.0	COG1309@1|root,COG1309@2|Bacteria,2HRRV@201174|Actinobacteria,4CTUM@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRD1_k127_1227341_0	398767.Glov_2401	8.178e-93	318.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria,43V0Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
SRD1_k127_1227341_2	398767.Glov_2400	8.336e-60	228.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,430HE@68525|delta/epsilon subdivisions,2WVZI@28221|Deltaproteobacteria,43V4N@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
SRD1_k127_1298460_1	512565.AMIS_69530	5.344e-34	136.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4D8I3@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the peptidase M16 family	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRD1_k127_1298460_2	411460.RUMTOR_00206	8.822e-32	132.0	COG0681@1|root,COG0681@2|Bacteria,1UZ8V@1239|Firmicutes,25CN7@186801|Clostridia,3Y2EX@572511|Blautia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
SRD1_k127_1298460_0	1378168.N510_01086	4.559e-55	201.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes	1239|Firmicutes	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRD1_k127_130687_2	398767.Glov_2399	1.706e-32	144.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,43V8M@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRD1_k127_130687_0	398767.Glov_2399	4.677e-87	304.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,43V8M@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRD1_k127_130687_1	398767.Glov_2400	3.584e-37	145.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,430HE@68525|delta/epsilon subdivisions,2WVZI@28221|Deltaproteobacteria,43V4N@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
SRD1_k127_131413_1	1223544.GSI01S_02_00300	1.28e-07	64.0	COG3559@1|root,COG3559@2|Bacteria,2GMSI@201174|Actinobacteria,4GACJ@85026|Gordoniaceae	201174|Actinobacteria	M	Exporter of polyketide	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRD1_k127_131413_0	661478.OP10G_1632	1.436e-64	231.0	COG1273@1|root,COG1273@2|Bacteria	2|Bacteria	M	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRD1_k127_1314813_3	58123.JOFJ01000003_gene2116	4.988e-17	89.0	COG0207@1|root,COG0207@2|Bacteria,2GYT8@201174|Actinobacteria,4EP7M@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	-	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRD1_k127_1314813_0	1382306.JNIM01000001_gene152	1.177e-55	208.0	COG0208@1|root,COG0208@2|Bacteria	2|Bacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
SRD1_k127_1314813_1	1500304.JQKY01000007_gene3276	1.783e-37	157.0	COG2114@1|root,COG2114@2|Bacteria,1Q8YH@1224|Proteobacteria,2VD35@28211|Alphaproteobacteria,4BA5X@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRD1_k127_1314813_4	1122915.AUGY01000083_gene4478	3.251e-11	77.0	COG0664@1|root,COG1413@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,1U0F2@1239|Firmicutes,4I9SK@91061|Bacilli,271XT@186822|Paenibacillaceae	91061|Bacilli	CT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRD1_k127_1316307_1	2325.TKV_c00060	2.722e-67	246.0	COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,24A80@186801|Clostridia,42FTD@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM CobB CobQ domain protein glutamine amidotransferase	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
SRD1_k127_1316307_0	1128421.JAGA01000003_gene3528	9.025e-111	390.0	COG0771@1|root,COG0771@2|Bacteria	2|Bacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	3.4.21.10,6.3.2.13,6.3.2.9	ko:K01317,ko:K01925,ko:K01928,ko:K01932	ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100	-	R02783,R02788	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01002,ko01011,ko04131	-	-	-	DUF1727,Mur_ligase_C,Mur_ligase_M
SRD1_k127_1316307_3	742821.HMPREF9464_00369	2.218e-30	135.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria,4PQUY@995019|Sutterellaceae	28216|Betaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRD1_k127_1316307_2	266117.Rxyl_1750	1.131e-53	193.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria,4CTCP@84995|Rubrobacteria	84995|Rubrobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRD1_k127_1316307_6	1121877.JQKF01000022_gene2300	7.058e-05	50.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,4CNBN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRD1_k127_1316307_4	1033810.HLPCO_000401	2.126e-12	79.0	COG1466@1|root,COG1466@2|Bacteria,2NPN5@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRD1_k127_1316307_5	552811.Dehly_0037	3.992e-09	66.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2G6G7@200795|Chloroflexi,34CYA@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Domain of unknown function (DUF4131)	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRD1_k127_132321_0	511051.CSE_05140	1.456e-29	127.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
SRD1_k127_132321_1	338963.Pcar_2564	7.311e-08	64.0	COG1073@1|root,COG1073@2|Bacteria,1R4QH@1224|Proteobacteria,43C0C@68525|delta/epsilon subdivisions,2WKKS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_132321_2	1283299.AUKG01000001_gene1443	1.729e-07	57.0	COG4274@1|root,COG4274@2|Bacteria,2HR6Q@201174|Actinobacteria,4CT2K@84995|Rubrobacteria	84995|Rubrobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRD1_k127_1327442_0	321955.AAGP01000017_gene2194	4.798e-307	953.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4FAN4@85019|Brevibacteriaceae	201174|Actinobacteria	E	FAD dependent oxidoreductase central domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRD1_k127_1327442_1	694430.Natoc_1418	4.326e-40	154.0	COG2086@1|root,arCOG00446@2157|Archaea,2XW02@28890|Euryarchaeota,23TZ0@183963|Halobacteria	183963|Halobacteria	C	Electron transfer flavoprotein, beta subunit	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRD1_k127_1333686_3	1306174.JODP01000004_gene1243	2.264e-22	102.0	COG1802@1|root,COG1802@2|Bacteria,2IBT4@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRD1_k127_1333686_1	1121877.JQKF01000012_gene342	7.496e-60	224.0	COG0683@1|root,COG0683@2|Bacteria,2HFKF@201174|Actinobacteria,4CP0G@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRD1_k127_1333686_2	449447.MAE_02170	5.614e-46	178.0	COG0559@1|root,COG0559@2|Bacteria,1G32V@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Branched-chain amino acid transport system permease component	natD	-	-	ko:K11956	ko02010,map02010	M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.2,3.A.1.4.6	-	-	BPD_transp_2
SRD1_k127_1333686_0	1121877.JQKF01000012_gene340	8.476e-65	237.0	COG4177@1|root,COG4177@2|Bacteria,2H4RR@201174|Actinobacteria	201174|Actinobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRD1_k127_1335432_0	555079.Toce_1732	4.927e-96	332.0	COG3408@1|root,COG3408@2|Bacteria,1TPX8@1239|Firmicutes,249BI@186801|Clostridia,42FGZ@68295|Thermoanaerobacterales	186801|Clostridia	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRD1_k127_1338179_10	215803.DB30_0233	9.003e-06	53.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase,HTH_24,MarR_2,Methyltransf_14,NTP_transf_3
SRD1_k127_1338179_11	365528.KB891116_gene1657	2.779e-05	55.0	COG3087@1|root,COG3087@2|Bacteria,2IBKJ@201174|Actinobacteria	201174|Actinobacteria	D	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1338179_9	391600.ABRU01000049_gene11	8.722e-21	107.0	COG0739@1|root,COG0739@2|Bacteria,1N4RU@1224|Proteobacteria,2UECF@28211|Alphaproteobacteria,2KH4S@204458|Caulobacterales	204458|Caulobacterales	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRD1_k127_1338179_6	319225.Plut_0261	7.082e-31	126.0	COG0629@1|root,COG0629@2|Bacteria,1FE0M@1090|Chlorobi	1090|Chlorobi	L	PFAM single-strand binding protein Primosomal replication protein n	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRD1_k127_1338179_3	309801.trd_A0313	8.201e-61	214.0	28M3Q@1|root,2ZAHT@2|Bacteria,2GBEH@200795|Chloroflexi,27Z5I@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1338179_0	485913.Krac_2570	8.136e-209	659.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
SRD1_k127_1338179_2	1217720.ALOX01000071_gene628	6.448e-71	249.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2TSUR@28211|Alphaproteobacteria,2JPQ8@204441|Rhodospirillales	204441|Rhodospirillales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRD1_k127_1338179_5	1394178.AWOO02000045_gene6410	5.097e-55	204.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
SRD1_k127_1338179_4	379066.GAU_1075	4.458e-59	212.0	COG0454@1|root,COG0454@2|Bacteria,1ZTWK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD1_k127_1338179_8	69395.JQLZ01000012_gene4327	3.039e-21	98.0	2DPVY@1|root,333MG@2|Bacteria,1NPT0@1224|Proteobacteria,2UKR4@28211|Alphaproteobacteria,2KHI2@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
SRD1_k127_1338179_7	1126627.BAWE01000003_gene1570	4.405e-25	116.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,2TUHQ@28211|Alphaproteobacteria,3JTWA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	MA20_22080	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRD1_k127_1338179_1	518766.Rmar_2101	3.112e-175	554.0	COG1830@1|root,COG1830@2|Bacteria,4NEUM@976|Bacteroidetes,1FIWN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	DeoC/LacD family aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SRD1_k127_1344389_1	886293.Sinac_4686	1.129e-57	202.0	COG0229@1|root,COG0229@2|Bacteria,2IZVK@203682|Planctomycetes	203682|Planctomycetes	O	peptide-methionine (R)-S-oxide reductase	-	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRD1_k127_1344389_4	443143.GM18_3141	1.099e-10	66.0	2DQBG@1|root,335T7@2|Bacteria,1R35T@1224|Proteobacteria,42ZVK@68525|delta/epsilon subdivisions,2WV6B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
SRD1_k127_1344389_3	706587.Desti_3193	1.154e-16	86.0	2DQBG@1|root,335T7@2|Bacteria,1R35T@1224|Proteobacteria,42ZVK@68525|delta/epsilon subdivisions,2WV6B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
SRD1_k127_1344389_0	479434.Sthe_3051	4.54e-81	285.0	COG0384@1|root,COG0384@2|Bacteria,2G7U6@200795|Chloroflexi,27ZAQ@189775|Thermomicrobia	189775|Thermomicrobia	S	Phenazine biosynthesis-like protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
SRD1_k127_1344389_2	28444.JODQ01000015_gene1756	3.899e-40	152.0	COG2050@1|root,COG2050@2|Bacteria,2IJ48@201174|Actinobacteria,4EK26@85012|Streptosporangiales	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRD1_k127_1344764_12	1345695.CLSA_c30470	4.682e-09	61.0	COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,24ACH@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRD1_k127_1344764_2	240016.ABIZ01000001_gene1830	2.791e-88	297.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRD1_k127_1344764_3	1122247.C731_3548	1.3e-78	276.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,232QT@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRD1_k127_1344764_13	1122611.KB903940_gene1681	2.726e-06	56.0	COG5637@1|root,COG5637@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BON,DUF2892,Polyketide_cyc,Polyketide_cyc2
SRD1_k127_1344764_0	1206731.BAGB01000023_gene1222	5.833e-175	569.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4G5I0@85025|Nocardiaceae	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD1_k127_1344764_8	1268072.PSAB_09390	2.012e-45	186.0	COG1309@1|root,COG1309@2|Bacteria,1VNJW@1239|Firmicutes,4HSYP@91061|Bacilli,275QV@186822|Paenibacillaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD1_k127_1344764_6	287986.DV20_04860	8.243e-51	188.0	COG4119@1|root,COG4119@2|Bacteria,2IM6D@201174|Actinobacteria,4E45T@85010|Pseudonocardiales	201174|Actinobacteria	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRD1_k127_1344764_1	1386089.N865_01840	4.444e-148	487.0	COG1404@1|root,COG1404@2|Bacteria,2GJ14@201174|Actinobacteria,4FG1N@85021|Intrasporangiaceae	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRD1_k127_1344764_10	485913.Krac_0922	2.443e-29	126.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD1_k127_1344764_4	448385.sce5984	5.073e-75	268.0	COG1801@1|root,COG1801@2|Bacteria,1N06I@1224|Proteobacteria,43BIA@68525|delta/epsilon subdivisions,2X6WP@28221|Deltaproteobacteria,2Z3DC@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRD1_k127_1344764_5	35754.JNYJ01000008_gene3329	6.981e-55	199.0	COG5587@1|root,COG5587@2|Bacteria,2IJG5@201174|Actinobacteria,4DDX6@85008|Micromonosporales	201174|Actinobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SRD1_k127_1344764_7	1382306.JNIM01000001_gene3976	1.607e-46	184.0	COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi	200795|Chloroflexi	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRD1_k127_1344764_9	525904.Tter_2282	7.834e-30	125.0	COG3685@1|root,COG3685@2|Bacteria	2|Bacteria	S	cellular response to DNA damage stimulus	yciE	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716	-	-	-	-	-	-	-	-	-	-	DUF892
SRD1_k127_134698_3	1246995.AFR_11275	1.3e-22	102.0	COG0498@1|root,COG0498@2|Bacteria,2GNZD@201174|Actinobacteria,4DCA6@85008|Micromonosporales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD1_k127_134698_0	1079986.JH164861_gene7370	3.213e-125	406.0	COG1073@1|root,COG1073@2|Bacteria,2I345@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRD1_k127_134698_1	443598.AUFA01000027_gene1914	1.199e-120	403.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2TT6G@28211|Alphaproteobacteria,3JWEQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_134698_5	357808.RoseRS_0106	1.389e-11	74.0	2DPX2@1|root,333RW@2|Bacteria,2G7A0@200795|Chloroflexi,377B3@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
SRD1_k127_134698_2	1229780.BN381_310018	5.469e-55	204.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.4.11.5	ko:K01259,ko:K19311	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Hydrolase_4
SRD1_k127_134698_6	1121946.AUAX01000046_gene7472	3.879e-07	63.0	2F0BY@1|root,33TF4@2|Bacteria,2ICQW@201174|Actinobacteria,4DIWK@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_134698_4	85982.XP_007316066.1	1.104e-13	79.0	COG0204@1|root,KOG2848@2759|Eukaryota,38GE5@33154|Opisthokonta,3NX4B@4751|Fungi,3UZXC@5204|Basidiomycota,224HH@155619|Agaricomycetes	4751|Fungi	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	SLC1	GO:0003674,GO:0003824,GO:0003841,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005811,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0012505,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0031984,GO:0042171,GO:0042175,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071617,GO:0071704,GO:0090407,GO:0098827,GO:1901576	2.3.1.51	ko:K13509	ko00561,ko00564,ko01100,ko01110,ko04072,ko04975,map00561,map00564,map01100,map01110,map04072,map04975	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRD1_k127_1356064_0	693977.Deipr_1687	4.12e-60	218.0	COG0226@1|root,COG0226@2|Bacteria,1WJ0E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Belongs to the PstS family	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRD1_k127_1356064_1	661478.OP10G_4188	1.516e-24	113.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	phoR	-	2.7.13.3	ko:K02484,ko:K07636,ko:K07768	ko02020,map02020	M00434,M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SRD1_k127_135705_5	309801.trd_0149	1.148e-35	140.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	iAF987.Gmet_2266	CCG,ETF,Fer4_8
SRD1_k127_135705_1	309801.trd_0150	1.874e-188	597.0	COG0247@1|root,COG0247@2|Bacteria,2G5X6@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG
SRD1_k127_135705_3	882083.SacmaDRAFT_1924	1.429e-68	241.0	2DPCA@1|root,331H2@2|Bacteria,2HCYY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_135705_2	562970.Btus_2496	2.246e-154	494.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_6,Pyr_redox_2
SRD1_k127_135705_0	1051632.TPY_3530	1.009e-195	616.0	COG2048@1|root,COG2048@2|Bacteria,1V67B@1239|Firmicutes,248DI@186801|Clostridia	186801|Clostridia	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
SRD1_k127_135705_7	1240349.ANGC01000014_gene640	1.447e-23	103.0	COG0640@1|root,COG0640@2|Bacteria,2IKPW@201174|Actinobacteria,4G2PA@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
SRD1_k127_135705_4	638303.Thal_1350	4.45e-48	179.0	COG2210@1|root,COG2210@2|Bacteria,2G565@200783|Aquificae	200783|Aquificae	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRD1_k127_135705_6	1417296.U879_08065	5.433e-28	117.0	COG2044@1|root,COG2044@2|Bacteria,1RGWS@1224|Proteobacteria,2UB97@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRD1_k127_135705_8	45130.XP_007704478.1	0.0002841	48.0	COG0596@1|root,KOG2565@2759|Eukaryota,38UTB@33154|Opisthokonta,3NVT5@4751|Fungi,3QKRW@4890|Ascomycota,204MT@147541|Dothideomycetes,4KBP5@92860|Pleosporales	4751|Fungi	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
SRD1_k127_1363608_0	1121946.AUAX01000003_gene1447	8.048e-17	94.0	COG2267@1|root,COG2267@2|Bacteria,2IGKW@201174|Actinobacteria,4DIAN@85008|Micromonosporales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRD1_k127_137681_3	1123501.KB902283_gene2283	5.04e-34	136.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Methionine synthase	-	-	2.1.1.14,4.4.1.23	ko:K00549,ko:K22363	ko00270,ko00450,ko00625,ko01100,ko01110,ko01230,map00270,map00450,map00625,map01100,map01110,map01230	M00017	R04405,R09365,R11897,R11899	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRD1_k127_137681_1	1185652.USDA257_c15630	6.145e-87	303.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2TRVF@28211|Alphaproteobacteria,4BAUP@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
SRD1_k127_137681_2	543728.Vapar_1313	1.344e-79	283.0	COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,2VMR4@28216|Betaproteobacteria,4ABKB@80864|Comamonadaceae	28216|Betaproteobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRD1_k127_137681_0	485913.Krac_9106	1.675e-92	315.0	COG0346@1|root,COG0346@2|Bacteria,2G7VB@200795|Chloroflexi	2|Bacteria	C	PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRD1_k127_137681_4	1298863.AUEP01000008_gene1241	0.0002845	49.0	29ZNQ@1|root,30MP9@2|Bacteria,2IJUR@201174|Actinobacteria,4DUE8@85009|Propionibacteriales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRD1_k127_1409592_2	861299.J421_6265	4.752e-43	170.0	COG2152@1|root,COG2152@2|Bacteria	2|Bacteria	G	transferase activity, transferring glycosyl groups	-	-	2.4.1.339,2.4.1.340	ko:K20885	-	-	R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
SRD1_k127_1409592_0	518766.Rmar_1363	1.63e-91	315.0	COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD1_k127_1409592_5	1166018.FAES_1554	1.335e-05	55.0	COG1331@1|root,COG1331@2|Bacteria,4NPQI@976|Bacteroidetes	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1409592_4	1095769.CAHF01000011_gene2583	3.003e-08	63.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,472HT@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_1409592_3	309801.trd_1301	2.463e-36	141.0	COG0234@1|root,COG0234@2|Bacteria,2G6WW@200795|Chloroflexi,27YJ2@189775|Thermomicrobia	189775|Thermomicrobia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRD1_k127_1409592_1	1273103.NM10_06911	8.058e-85	286.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4H29X@909932|Negativicutes	909932|Negativicutes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRD1_k127_1416237_1	1121272.KB903249_gene1360	2.025e-35	145.0	2D2DJ@1|root,32TCJ@2|Bacteria,2GR1K@201174|Actinobacteria,4DKK0@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1416237_2	1121272.KB903249_gene1360	6.015e-32	134.0	2D2DJ@1|root,32TCJ@2|Bacteria,2GR1K@201174|Actinobacteria,4DKK0@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1416237_3	235985.BBPN01000021_gene6317	6.955e-23	104.0	2DSUM@1|root,33HGR@2|Bacteria,2ING4@201174|Actinobacteria,2NJHI@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1416237_0	926550.CLDAP_20530	3.512e-48	188.0	COG1131@1|root,COG1131@2|Bacteria,2G6HA@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRD1_k127_142222_0	561175.KB894095_gene2595	2.243e-104	351.0	COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,4EIC0@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRD1_k127_142222_4	1206737.BAGF01000152_gene6456	2.272e-06	60.0	28HBI@1|root,2Z7NH@2|Bacteria,2I3ZC@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4241)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4241
SRD1_k127_142222_3	671143.DAMO_0317	3.426e-14	85.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,CBM_35,DUF1080,PKD
SRD1_k127_142222_2	557599.MKAN_12095	1.14e-25	119.0	COG0515@1|root,COG3055@1|root,COG0515@2|Bacteria,COG3055@2|Bacteria,2I4I0@201174|Actinobacteria,23F8F@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	PFAM Protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Pkinase
SRD1_k127_142222_1	485913.Krac_4453	2.986e-89	302.0	COG0701@1|root,COG0701@2|Bacteria	2|Bacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
SRD1_k127_1430429_1	414996.IL38_04245	2.778e-73	259.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,408UF@622450|Actinopolysporales	201174|Actinobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRD1_k127_1430429_0	1292034.OR37_01610	1.022e-163	526.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2TSHK@28211|Alphaproteobacteria,2KFB5@204458|Caulobacterales	204458|Caulobacterales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD1_k127_1430429_3	760568.Desku_1853	1.019e-42	169.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,2623G@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRD1_k127_1430429_2	309801.trd_0105	4.132e-46	170.0	COG0134@1|root,COG0134@2|Bacteria,2G6GG@200795|Chloroflexi,27XGP@189775|Thermomicrobia	189775|Thermomicrobia	E	Indole-3-glycerol phosphate synthase	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRD1_k127_1450650_3	645512.GCWU000246_01628	7.539e-45	168.0	COG0012@1|root,COG0012@2|Bacteria,3TA1V@508458|Synergistetes	508458|Synergistetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRD1_k127_1450650_5	485913.Krac_11108	6.731e-22	102.0	COG4420@1|root,COG4420@2|Bacteria,2G98R@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
SRD1_k127_1450650_1	552811.Dehly_1466	9.362e-117	388.0	COG0003@1|root,COG0003@2|Bacteria,2G64V@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRD1_k127_1450650_4	643562.Daes_2473	4.458e-22	105.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,42STM@68525|delta/epsilon subdivisions,2WPAD@28221|Deltaproteobacteria,2MB8X@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRD1_k127_1450650_2	867903.ThesuDRAFT_00101	8.997e-111	383.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,3WCCS@538999|Clostridiales incertae sedis	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRD1_k127_1450650_0	309801.trd_0508	2.785e-156	521.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi,27XRW@189775|Thermomicrobia	189775|Thermomicrobia	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRD1_k127_145845_1	469382.Hbor_17360	5.384e-06	49.0	COG0473@1|root,arCOG01163@2157|Archaea,2XT99@28890|Euryarchaeota,23TK7@183963|Halobacteria	183963|Halobacteria	C	Isocitrate isopropylmalate dehydrogenase	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRD1_k127_145845_0	1121428.DESHY_150098___1	2.859e-157	506.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,2617C@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRD1_k127_1481423_0	1121403.AUCV01000020_gene3088	6.883e-101	338.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42MCE@68525|delta/epsilon subdivisions,2WIYP@28221|Deltaproteobacteria,2MMID@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
SRD1_k127_1481423_2	342949.PNA2_1811	4.556e-09	69.0	COG3463@1|root,arCOG03812@2157|Archaea,2Y1AV@28890|Euryarchaeota,2432A@183968|Thermococci	183968|Thermococci	S	Predicted membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
SRD1_k127_1481423_1	2002.JOEQ01000042_gene5905	3.882e-89	299.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4EFW6@85012|Streptosporangiales	201174|Actinobacteria	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRD1_k127_1488883_3	397278.JOJN01000007_gene3423	4.367e-35	138.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4DPDX@85009|Propionibacteriales	201174|Actinobacteria	L	DEAD/H associated	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
SRD1_k127_1488883_2	266117.Rxyl_1781	2.869e-45	169.0	COG1853@1|root,COG1853@2|Bacteria,2GPJS@201174|Actinobacteria,4CQK3@84995|Rubrobacteria	84995|Rubrobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRD1_k127_1488883_4	1082931.KKY_1808	2.207e-31	140.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria,3N6UN@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	O	cytochrome c biogenesis protein	MA20_17170	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRD1_k127_1488883_1	591158.SSMG_05537	7.402e-83	284.0	COG2021@1|root,COG2021@2|Bacteria,2I3NA@201174|Actinobacteria	201174|Actinobacteria	E	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRD1_k127_1488883_0	326427.Cagg_0130	1.487e-211	673.0	COG1164@1|root,COG1164@2|Bacteria,2G5UV@200795|Chloroflexi,376XT@32061|Chloroflexia	32061|Chloroflexia	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
SRD1_k127_1488883_5	1313172.YM304_05050	2.792e-12	68.0	COG0454@1|root,COG0456@2|Bacteria,2IMVD@201174|Actinobacteria,4CNB7@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD1_k127_1538072_3	887898.HMPREF0551_1357	0.0001078	54.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria,1K1F2@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Domain of unknown function (DUF3488)	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
SRD1_k127_1538072_2	886293.Sinac_2134	2.022e-12	78.0	COG1721@1|root,COG1721@2|Bacteria,2IZI6@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRD1_k127_1538072_0	1521187.JPIM01000232_gene2766	3.12e-98	330.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi,374V5@32061|Chloroflexia	32061|Chloroflexia	S	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRD1_k127_1538072_1	221027.JO40_06650	2.053e-15	80.0	COG1239@1|root,COG1239@2|Bacteria,2J7CG@203691|Spirochaetes	203691|Spirochaetes	H	AAA domain (dynein-related subfamily)	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase
SRD1_k127_1560518_5	404589.Anae109_1337	5.058e-20	102.0	COG3075@1|root,COG3075@2|Bacteria,1MU3K@1224|Proteobacteria,42Q09@68525|delta/epsilon subdivisions,2WKE0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	glpB	-	1.1.5.3	ko:K00112	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
SRD1_k127_1560518_2	525904.Tter_2454	4.308e-76	280.0	COG0277@1|root,COG0277@2|Bacteria,2NQC6@2323|unclassified Bacteria	2|Bacteria	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803,ko:K11472	ko00565,ko00630,ko01100,ko01110,ko01120,ko01130,ko04146,map00565,map00630,map01100,map01110,map01120,map01130,map04146	-	R00475,R04311	RC00020,RC00042,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRD1_k127_1560518_3	373903.Hore_15890	9.347e-58	213.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,25CN4@186801|Clostridia,3WB2H@53433|Halanaerobiales	186801|Clostridia	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRD1_k127_1560518_0	479434.Sthe_1347	8.942e-112	378.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,27Y0Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRD1_k127_1560518_4	883069.HMPREF9238_00356	1.045e-29	121.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4D5ZB@85005|Actinomycetales	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRD1_k127_1560518_1	1382306.JNIM01000001_gene96	3.818e-89	301.0	COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi	200795|Chloroflexi	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRD1_k127_1577922_2	1463909.KL585949_gene6462	3.408e-40	152.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRD1_k127_1577922_1	1123319.AUBE01000002_gene1235	7.096e-77	262.0	COG0512@1|root,COG0512@2|Bacteria,2IGEI@201174|Actinobacteria	201174|Actinobacteria	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRD1_k127_1577922_0	1123319.AUBE01000002_gene1236	1.471e-77	263.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria	201174|Actinobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRD1_k127_158140_3	309801.trd_0308	3.843e-34	132.0	COG0605@1|root,COG0605@2|Bacteria,2G5Q9@200795|Chloroflexi,27Y8G@189775|Thermomicrobia	189775|Thermomicrobia	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRD1_k127_158140_4	309801.trd_0781	8.879e-05	48.0	COG1314@1|root,COG1314@2|Bacteria,2G7D9@200795|Chloroflexi,27YMZ@189775|Thermomicrobia	189775|Thermomicrobia	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRD1_k127_158140_0	479434.Sthe_1249	3.071e-71	261.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi,27XPP@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD1_k127_158140_1	675635.Psed_3724	6.294e-60	233.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4EBD9@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD1_k127_158140_2	1487923.DP73_14965	2.447e-42	160.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,25ZZ5@186807|Peptococcaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRD1_k127_1653431_2	868595.Desca_1025	1.032e-57	208.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,260YT@186807|Peptococcaceae	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRD1_k127_1653431_0	886882.PPSC2_c1766	5.494e-201	656.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,26QXQ@186822|Paenibacillaceae	91061|Bacilli	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
SRD1_k127_1653431_4	765420.OSCT_1025	7.223e-45	169.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi,3772Y@32061|Chloroflexia	32061|Chloroflexia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRD1_k127_1653431_5	1128421.JAGA01000003_gene2863	2.113e-33	142.0	COG1285@1|root,COG1285@2|Bacteria,2NPSV@2323|unclassified Bacteria	2|Bacteria	S	MgtC family	mgtC	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
SRD1_k127_1653431_1	479434.Sthe_1904	1.197e-58	226.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi,27YU3@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRD1_k127_1653431_3	1122609.AUGT01000017_gene824	7.859e-49	187.0	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4DP2U@85009|Propionibacteriales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRD1_k127_1653431_6	744979.R2A130_1567	6.821e-08	57.0	COG3255@1|root,COG3255@2|Bacteria	2|Bacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRD1_k127_1683447_3	479434.Sthe_0413	2.159e-34	148.0	COG0477@1|root,COG2814@2|Bacteria,2G8SG@200795|Chloroflexi,27XS0@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD1_k127_1683447_2	1382306.JNIM01000001_gene2708	2.889e-40	156.0	COG0586@1|root,COG0586@2|Bacteria,2G79V@200795|Chloroflexi	200795|Chloroflexi	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
SRD1_k127_1683447_0	525904.Tter_0121	5.219e-190	611.0	COG0441@1|root,COG0441@2|Bacteria,2NNMT@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRD1_k127_1683447_6	378806.STAUR_7519	0.0005545	52.0	COG0457@1|root,COG0457@2|Bacteria,1QEEQ@1224|Proteobacteria,433Z2@68525|delta/epsilon subdivisions,2X451@28221|Deltaproteobacteria,2YY9W@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
SRD1_k127_1683447_1	868595.Desca_1052	1.103e-59	211.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,260V8@186807|Peptococcaceae	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRD1_k127_1683447_4	1235794.C811_00354	1.851e-06	52.0	COG0291@1|root,COG0291@2|Bacteria,2HV94@201174|Actinobacteria,4CWHW@84998|Coriobacteriia	84998|Coriobacteriia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRD1_k127_1683447_5	1121861.KB899912_gene1096	9.551e-05	44.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2U756@28211|Alphaproteobacteria,2JSNZ@204441|Rhodospirillales	204441|Rhodospirillales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRD1_k127_1684424_6	525904.Tter_0756	2.458e-32	130.0	COG1595@1|root,COG1595@2|Bacteria,2NPHU@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma factor	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_1684424_9	1172188.KB911821_gene1673	4.96e-09	60.0	COG5662@1|root,COG5662@2|Bacteria,2IM2X@201174|Actinobacteria,4FHE6@85021|Intrasporangiaceae	201174|Actinobacteria	K	Putative zinc-finger	rsrA	GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRD1_k127_1684424_5	756272.Plabr_4061	1.826e-32	136.0	COG0352@1|root,COG0352@2|Bacteria,2IY16@203682|Planctomycetes	203682|Planctomycetes	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Clp_N,TMP-TENI
SRD1_k127_1684424_4	1242864.D187_001096	1.266e-32	142.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2WNGE@28221|Deltaproteobacteria,2YVMB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRD1_k127_1684424_7	266940.Krad_0729	1.873e-24	108.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria	201174|Actinobacteria	K	ATPase or kinase	tsaE	GO:0008150,GO:0040007	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRD1_k127_1684424_8	401053.AciPR4_0942	1.039e-09	66.0	COG1214@1|root,COG1214@2|Bacteria,3Y5ED@57723|Acidobacteria,2JJSB@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM Peptidase M22, glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRD1_k127_1684424_2	479434.Sthe_0914	1.143e-39	154.0	COG0454@1|root,COG0456@2|Bacteria,2G6TF@200795|Chloroflexi,27Y7H@189775|Thermomicrobia	189775|Thermomicrobia	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRD1_k127_1684424_1	696281.Desru_0743	3.062e-92	323.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,260QV@186807|Peptococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRD1_k127_1684424_3	747365.Thena_0043	1.31e-38	147.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,42GV4@68295|Thermoanaerobacterales	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRD1_k127_1684424_0	401526.TcarDRAFT_0384	1.895e-149	479.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4H29X@909932|Negativicutes	909932|Negativicutes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRD1_k127_170578_2	552811.Dehly_1213	7.419e-50	195.0	COG2211@1|root,COG2211@2|Bacteria,2G8SN@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_170578_0	935836.JAEL01000082_gene1046	5.309e-148	481.0	COG1960@1|root,COG1960@2|Bacteria,1TPVK@1239|Firmicutes,4HA7B@91061|Bacilli,1ZBM4@1386|Bacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	B4168_2380	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_170578_1	65497.JODV01000014_gene3394	1.248e-65	247.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4DXSW@85010|Pseudonocardiales	201174|Actinobacteria	D	involved in chromosome partitioning	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRD1_k127_170578_3	696281.Desru_3268	2.443e-38	150.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,261Y2@186807|Peptococcaceae	186801|Clostridia	P	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRD1_k127_170578_4	46234.ANA_C10282	3.974e-05	51.0	2DB7J@1|root,2Z7MI@2|Bacteria,1G2I3@1117|Cyanobacteria,1HJGU@1161|Nostocales	1117|Cyanobacteria	S	PFAM S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
SRD1_k127_1711772_2	266117.Rxyl_1748	1.776e-71	249.0	COG1024@1|root,COG1024@2|Bacteria,2GNXD@201174|Actinobacteria,4CQCF@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD1_k127_1711772_1	1227360.C176_18066	5.733e-76	265.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,26EA2@186818|Planococcaceae	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SRD1_k127_1711772_4	562970.Btus_3147	1.999e-05	53.0	2DQT5@1|root,338GV@2|Bacteria,1VEES@1239|Firmicutes,4HNWP@91061|Bacilli,278NG@186823|Alicyclobacillaceae	91061|Bacilli	-	-	M1-488	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1711772_0	1382306.JNIM01000001_gene331	5.602e-88	298.0	COG2057@1|root,COG2057@2|Bacteria,2G6MS@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRD1_k127_171751_0	1267535.KB906767_gene2325	6.25e-35	140.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria,2JIZJ@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_171751_1	1210884.HG799464_gene10535	1.01e-28	121.0	COG1247@1|root,COG1247@2|Bacteria,2J0C9@203682|Planctomycetes	203682|Planctomycetes	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
SRD1_k127_171751_2	78245.Xaut_1620	7.772e-16	87.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2U0KM@28211|Alphaproteobacteria,3F1B6@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRD1_k127_1722924_1	479432.Sros_4171	2.233e-74	269.0	COG0654@1|root,COG0654@2|Bacteria,2I901@201174|Actinobacteria	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,NAD_binding_8,Trp_halogenase
SRD1_k127_1722924_0	298654.FraEuI1c_0848	1.486e-128	422.0	COG0446@1|root,COG0446@2|Bacteria,2GRTN@201174|Actinobacteria,4ESWT@85013|Frankiales	201174|Actinobacteria	S	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DsrC,Pyr_redox_2
SRD1_k127_1722924_2	266117.Rxyl_2353	3.936e-72	250.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria,4CSPT@84995|Rubrobacteria	84995|Rubrobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRD1_k127_175193_3	453591.Igni_0512	4.102e-21	104.0	COG0373@1|root,arCOG01036@2157|Archaea,2XQHB@28889|Crenarchaeota	28889|Crenarchaeota	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRD1_k127_175193_2	710696.Intca_1870	2.009e-21	101.0	COG2452@1|root,COG2452@2|Bacteria	2|Bacteria	L	recombinase activity	guaB2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07450	-	-	-	-	ko00000	-	-	-	MerR,MerR_1,Resolvase
SRD1_k127_175193_1	1455608.JDTH01000001_gene3182	4.843e-27	124.0	COG2258@1|root,arCOG11383@2157|Archaea,2XXK8@28890|Euryarchaeota,23VKF@183963|Halobacteria	183963|Halobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRD1_k127_175193_4	105422.BBPM01000094_gene5281	2.127e-20	100.0	2E39M@1|root,32Y96@2|Bacteria,2IITE@201174|Actinobacteria,2NJ8S@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_175193_0	1303518.CCALI_00612	3.087e-130	433.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRD1_k127_1776423_2	298655.KI912267_gene7455	3.1e-39	157.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD1_k127_1776423_1	1380390.JIAT01000012_gene3233	1.52e-40	164.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4CS0M@84995|Rubrobacteria	84995|Rubrobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRD1_k127_1776423_0	1211814.CAPG01000003_gene42	6.346e-66	247.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli,1ZB0Q@1386|Bacillus	91061|Bacilli	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRD1_k127_1803248_0	357808.RoseRS_3160	3.723e-53	202.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi,374YS@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRD1_k127_1859086_3	479434.Sthe_2066	4.627e-36	142.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
SRD1_k127_1859086_7	1128427.KB904821_gene1085	5.874e-11	74.0	COG4188@1|root,COG4188@2|Bacteria,1FZWS@1117|Cyanobacteria,1H817@1150|Oscillatoriales	1117|Cyanobacteria	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,DUF1400,PAF-AH_p_II
SRD1_k127_1859086_5	1197706.AKKK01000006_gene1206	1.455e-14	82.0	COG3070@1|root,COG3070@2|Bacteria,2IRAD@201174|Actinobacteria	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRD1_k127_1859086_8	555079.Toce_2267	2.172e-08	62.0	COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,24QT5@186801|Clostridia,42GQS@68295|Thermoanaerobacterales	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRD1_k127_1859086_6	690850.Desaf_1578	6.365e-13	74.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2MBWU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRD1_k127_1859086_0	479434.Sthe_3070	3.506e-129	431.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRD1_k127_1859086_4	926560.KE387027_gene263	8.871e-30	128.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRD1_k127_1859086_2	2002.JOEQ01000005_gene3526	2.431e-48	181.0	2CBRB@1|root,33SV2@2|Bacteria,2IJ64@201174|Actinobacteria,4EJ8Z@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1859086_1	42256.RradSPS_2749	8.789e-117	382.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CPFP@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD1_k127_186118_2	981369.JQMJ01000004_gene4460	4.474e-13	72.0	COG1846@1|root,COG1846@2|Bacteria,2IRPE@201174|Actinobacteria,2NJNT@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRD1_k127_186118_0	1123229.AUBC01000018_gene3722	3.263e-95	329.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,2TSV7@28211|Alphaproteobacteria,3JXW4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRD1_k127_186118_3	1172181.KB911703_gene190	1.136e-10	74.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_10,TPR_12,TPR_7,TPR_8,Trans_reg_C
SRD1_k127_186118_1	1254432.SCE1572_17210	1.812e-29	129.0	COG0454@1|root,COG0454@2|Bacteria,1QZHM@1224|Proteobacteria,43CIQ@68525|delta/epsilon subdivisions,2WWHV@28221|Deltaproteobacteria,2Z207@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD1_k127_1871412_1	1122939.ATUD01000004_gene3710	1.006e-106	370.0	COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria,2GJ75@201174|Actinobacteria,4CPFI@84995|Rubrobacteria	84995|Rubrobacteria	ET	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,Usp
SRD1_k127_1871412_0	1382306.JNIM01000001_gene1548	2.725e-126	427.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_1871412_2	1121377.KB906409_gene862	8.946e-100	342.0	COG0006@1|root,COG0006@2|Bacteria,1WIXQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRD1_k127_1871412_3	326427.Cagg_2096	8.904e-92	305.0	COG0022@1|root,COG0022@2|Bacteria,2G5JU@200795|Chloroflexi,374SG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Transketolase central region	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRD1_k127_190986_3	926564.KI911760_gene4972	9.297e-37	146.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4F5CQ@85017|Promicromonosporaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	kdpE	GO:0008150,GO:0040007	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_190986_2	78245.Xaut_3237	2.555e-40	168.0	COG2156@1|root,COG2156@2|Bacteria,1RABG@1224|Proteobacteria,2TSQ7@28211|Alphaproteobacteria,3EZD6@335928|Xanthobacteraceae	28211|Alphaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
SRD1_k127_190986_0	1169161.KB897713_gene6950	1.353e-279	878.0	COG2216@1|root,COG2216@2|Bacteria,2GIWT@201174|Actinobacteria	201174|Actinobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
SRD1_k127_190986_1	485913.Krac_1219	8.141e-191	614.0	COG2060@1|root,COG2060@2|Bacteria,2G5KK@200795|Chloroflexi	200795|Chloroflexi	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	-	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
SRD1_k127_190986_4	366602.Caul_2695	8.007e-11	64.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,2KF1T@204458|Caulobacterales	204458|Caulobacterales	T	Histidine kinase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD
SRD1_k127_2015485_0	709986.Deima_2224	0.0	1079.0	COG0745@1|root,COG0784@1|root,COG1511@1|root,COG2770@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG1511@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	MA20_07280	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRD1_k127_2015485_1	1487953.JMKF01000005_gene617	1.01e-80	284.0	COG1352@1|root,COG1352@2|Bacteria,1G1E5@1117|Cyanobacteria,1H94K@1150|Oscillatoriales	1117|Cyanobacteria	NT	PFAM CheR methyltransferase, SAM binding domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
SRD1_k127_2015485_2	1120999.JONM01000007_gene1751	7.037e-73	269.0	COG0642@1|root,COG2199@1|root,COG4251@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria	28216|Betaproteobacteria	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
SRD1_k127_2015485_3	656024.FsymDg_1645	2.317e-15	84.0	COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,4ESQZ@85013|Frankiales	201174|Actinobacteria	M	PFAM peptidase C60, sortase A and B	srtB	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRD1_k127_2023226_0	1150864.MILUP08_45981	1.772e-97	328.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,4D9MG@85008|Micromonosporales	201174|Actinobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRD1_k127_2023226_1	1077972.ARGLB_113_00660	5.617e-14	77.0	COG3631@1|root,COG3631@2|Bacteria,2IJ9D@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SRD1_k127_2023226_2	84588.SYNW1598	1.549e-08	61.0	COG0745@1|root,COG0745@2|Bacteria,1GDAV@1117|Cyanobacteria,1GZXS@1129|Synechococcus	1117|Cyanobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRD1_k127_2026367_2	103733.JNYO01000030_gene1458	3.239e-13	82.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4E23C@85010|Pseudonocardiales	201174|Actinobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRD1_k127_2026367_1	1379698.RBG1_1C00001G1071	1.913e-17	93.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRD1_k127_2026367_0	240015.ACP_3542	8.405e-92	316.0	COG0624@1|root,COG0624@2|Bacteria,3Y3TZ@57723|Acidobacteria,2JIUW@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRD1_k127_2036519_0	269799.Gmet_1676	1.144e-150	486.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,42M9Z@68525|delta/epsilon subdivisions,2WIYZ@28221|Deltaproteobacteria,43U0G@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRD1_k127_2052446_2	1148.1653943	5.09e-103	345.0	COG0549@1|root,COG0549@2|Bacteria,1GAQG@1117|Cyanobacteria	1117|Cyanobacteria	F	Belongs to the carbamate kinase family	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRD1_k127_2052446_8	330084.JNYZ01000002_gene1638	6.144e-13	80.0	2EIHP@1|root,33C91@2|Bacteria,2ICMY@201174|Actinobacteria,4EC8S@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
SRD1_k127_2052446_7	298654.FraEuI1c_0532	2.29e-65	235.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRD1_k127_2052446_5	584708.Apau_0507	2.307e-75	267.0	COG4603@1|root,COG4603@2|Bacteria,3TAAN@508458|Synergistetes	508458|Synergistetes	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRD1_k127_2052446_1	926550.CLDAP_02200	2.578e-113	387.0	COG3845@1|root,COG3845@2|Bacteria,2G68B@200795|Chloroflexi	200795|Chloroflexi	S	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRD1_k127_2052446_3	1380394.JADL01000011_gene3801	1.339e-96	336.0	COG0074@1|root,COG0074@2|Bacteria,1MWWN@1224|Proteobacteria,2TTYT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,Ligase_CoA
SRD1_k127_2052446_0	1298867.AUES01000001_gene1708	4.034e-121	402.0	COG0074@1|root,COG0074@2|Bacteria,1MX67@1224|Proteobacteria,2U0AT@28211|Alphaproteobacteria,3JX2B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1116
SRD1_k127_2052446_6	1122917.KB899661_gene959	2.696e-74	264.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HF7R@91061|Bacilli,26QEK@186822|Paenibacillaceae	91061|Bacilli	S	membrane	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRD1_k127_2052446_4	351607.Acel_1545	3.309e-89	309.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4ERWA@85013|Frankiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpE	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
SRD1_k127_2052859_1	1380393.JHVP01000001_gene2285	6.113e-92	312.0	COG1228@1|root,COG1228@2|Bacteria,2IE2S@201174|Actinobacteria	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRD1_k127_2052859_7	981369.JQMJ01000004_gene4606	2.066e-37	149.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria,2NIZ7@228398|Streptacidiphilus	201174|Actinobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRD1_k127_2052859_10	66875.JODY01000048_gene3110	4.107e-25	116.0	COG1846@1|root,COG1846@2|Bacteria,2GJ6W@201174|Actinobacteria	201174|Actinobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRD1_k127_2052859_11	512565.AMIS_31290	2.754e-20	97.0	COG0662@1|root,COG0662@2|Bacteria,2IEY0@201174|Actinobacteria,4DDRC@85008|Micromonosporales	201174|Actinobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD1_k127_2052859_5	1123023.JIAI01000002_gene5869	1.232e-63	236.0	COG0477@1|root,COG0477@2|Bacteria,2I31V@201174|Actinobacteria,4E1WF@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD1_k127_2052859_9	1267535.KB906767_gene2770	5.76e-30	125.0	COG2898@1|root,COG2898@2|Bacteria,3Y4M0@57723|Acidobacteria,2JJ8Z@204432|Acidobacteriia	204432|Acidobacteriia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2052859_4	1380390.JIAT01000010_gene4196	9.379e-69	243.0	COG2197@1|root,COG2197@2|Bacteria,2HQF1@201174|Actinobacteria,4CRZT@84995|Rubrobacteria	84995|Rubrobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD1_k127_2052859_3	298655.KI912266_gene533	2.12e-82	301.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I8X1@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HisKA_3
SRD1_k127_2052859_8	706587.Desti_0084	3.576e-32	139.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2MQDX@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SRD1_k127_2052859_0	1136417.AZWE01000005_gene4552	3.733e-134	437.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4DBBX@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD1_k127_2052859_2	66429.JOFL01000024_gene5926	2.799e-88	310.0	COG0402@1|root,COG0402@2|Bacteria,2IB7M@201174|Actinobacteria	201174|Actinobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRD1_k127_2052859_6	926560.KE387023_gene2224	5.999e-50	188.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	eryCVI	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0046983	2.1.1.234	ko:K13311,ko:K13326,ko:K21335	ko00523,ko01130,map00523,map01130	M00797,M00800	R06427,R11045,R11476	RC00003,RC01515,RC02262	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
SRD1_k127_2058581_2	1267535.KB906767_gene1609	7.18e-05	50.0	arCOG07533@1|root,2ZF5I@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRD1_k127_2058581_0	298655.KI912266_gene2769	1.374e-226	716.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4ERYX@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRD1_k127_2059102_1	1869.MB27_42525	8.673e-87	296.0	COG1752@1|root,COG1752@2|Bacteria,2IB0F@201174|Actinobacteria,4DCP2@85008|Micromonosporales	201174|Actinobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRD1_k127_2059102_6	485913.Krac_1964	6.166e-37	154.0	COG3945@1|root,COG3945@2|Bacteria,2G96X@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRD1_k127_2059102_2	1105029.HMPREF1137_0886	4.382e-81	285.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4D33Q@85005|Actinomycetales	201174|Actinobacteria	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRD1_k127_2059102_5	345341.KUTG_08092	2.78e-48	194.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRD1_k127_2059102_10	75379.Tint_0600	9.345e-23	112.0	COG0526@1|root,COG0526@2|Bacteria,1RHR7@1224|Proteobacteria,2WEG9@28216|Betaproteobacteria,1KPKG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbC,LGT,Redoxin
SRD1_k127_2059102_7	1382306.JNIM01000001_gene4039	1.235e-35	149.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi	200795|Chloroflexi	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
SRD1_k127_2059102_4	357808.RoseRS_0224	2.323e-70	260.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,375H6@32061|Chloroflexia	32061|Chloroflexia	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRD1_k127_2059102_8	68570.DC74_1424	6.063e-31	137.0	COG0491@1|root,COG0491@2|Bacteria,2IB2K@201174|Actinobacteria	201174|Actinobacteria	S	beta-lactamase domain protein	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRD1_k127_2059102_3	383372.Rcas_0321	1.456e-76	267.0	COG2897@1|root,COG2897@2|Bacteria,2G6J9@200795|Chloroflexi,377XD@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRD1_k127_2059102_0	266117.Rxyl_0853	1.214e-94	316.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria,4CP6Q@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD1_k127_2059102_11	323259.Mhun_2044	0.0007138	50.0	COG2314@1|root,arCOG03293@2157|Archaea,2XYU1@28890|Euryarchaeota,2NB9D@224756|Methanomicrobia	224756|Methanomicrobia	T	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
SRD1_k127_2059102_9	298653.Franean1_5603	7.282e-25	109.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4ETRN@85013|Frankiales	201174|Actinobacteria	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_2077351_0	1048339.KB913029_gene1694	3.842e-128	423.0	COG0467@1|root,COG0467@2|Bacteria,2I58C@201174|Actinobacteria	201174|Actinobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SRD1_k127_2077351_1	309801.trd_1847	8.361e-116	395.0	COG1529@1|root,COG1529@2|Bacteria,2G82V@200795|Chloroflexi,27XQT@189775|Thermomicrobia	189775|Thermomicrobia	C	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRD1_k127_2102373_2	1121422.AUMW01000012_gene2919	1.47e-44	173.0	COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,2493V@186801|Clostridia,260QU@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRD1_k127_2102373_0	1122138.AQUZ01000013_gene5704	2.738e-104	351.0	COG0665@1|root,COG0665@2|Bacteria,2GNAE@201174|Actinobacteria,4DPFK@85009|Propionibacteriales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRD1_k127_2102373_1	1121468.AUBR01000010_gene2426	6.12e-48	183.0	COG0702@1|root,COG0702@2|Bacteria,1TWZS@1239|Firmicutes,24EGR@186801|Clostridia,42H7V@68295|Thermoanaerobacterales	186801|Clostridia	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
SRD1_k127_2102373_3	1430440.MGMSRv2_3265	7.913e-09	68.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2U7FV@28211|Alphaproteobacteria,2JSQA@204441|Rhodospirillales	204441|Rhodospirillales	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRD1_k127_2113598_2	1379698.RBG1_1C00001G0618	1.422e-20	105.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria	2|Bacteria	EU	peptidase S9 prolyl oligopeptidase active site	yuxL	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
SRD1_k127_2113598_3	357808.RoseRS_1781	5.711e-14	84.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,37509@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
SRD1_k127_2113598_1	644966.Tmar_1516	1.961e-27	116.0	COG3255@1|root,COG3255@2|Bacteria,1V7IH@1239|Firmicutes	1239|Firmicutes	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRD1_k127_2113598_0	1120950.KB892745_gene2887	1.329e-42	164.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4DQT0@85009|Propionibacteriales	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRD1_k127_212076_3	1449355.JQNR01000005_gene3109	4.14e-07	58.0	2DR37@1|root,339ZB@2|Bacteria,2IK6U@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_212076_0	66377.JOBH01000013_gene1751	7.462e-60	221.0	COG1247@1|root,COG1247@2|Bacteria,2IHSY@201174|Actinobacteria	201174|Actinobacteria	M	acetyltransferase	bar	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
SRD1_k127_212076_2	3750.XP_008387124.1	1.56e-23	108.0	COG1539@1|root,2RZV8@2759|Eukaryota,37UEQ@33090|Viridiplantae,3GIVM@35493|Streptophyta,4JQRG@91835|fabids	35493|Streptophyta	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	-	GO:0003674,GO:0003824,GO:0004150,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044444,GO:0044464	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRD1_k127_212076_1	1128421.JAGA01000002_gene622	2.291e-31	128.0	COG1641@1|root,COG1641@2|Bacteria,2NNX0@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF111	larC	-	4.99.1.12	ko:K06898,ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRD1_k127_2122979_2	1123250.KB908402_gene2163	9.506e-128	417.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,4H28E@909932|Negativicutes	909932|Negativicutes	U	PFAM Type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRD1_k127_2122979_4	517418.Ctha_0605	9.517e-79	287.0	COG0784@1|root,COG2198@1|root,COG3292@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,1FDBJ@1090|Chlorobi	1090|Chlorobi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,Response_reg,dCache_3
SRD1_k127_2122979_3	562970.Btus_1091	8.536e-109	366.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,277Y8@186823|Alicyclobacillaceae	91061|Bacilli	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA-synt_His
SRD1_k127_2122979_1	335541.Swol_0812	2.074e-176	578.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,42JQI@68298|Syntrophomonadaceae	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRD1_k127_2122979_7	1210045.ALNP01000011_gene986	1.07e-05	54.0	COG2172@1|root,COG2172@2|Bacteria,2IHNR@201174|Actinobacteria	201174|Actinobacteria	T	anti-sigma regulatory factor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
SRD1_k127_2122979_5	742722.HMPREF9463_01497	1.545e-64	229.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4CUM2@84998|Coriobacteriia	84998|Coriobacteriia	K	RNA polymerase sigma-70 factor, sigma-B F G subfamily	-	-	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD1_k127_2122979_6	309807.SRU_0544	1.417e-54	200.0	COG0259@1|root,COG0259@2|Bacteria,4NFH7@976|Bacteroidetes,1FJ7D@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SRD1_k127_2122979_0	525904.Tter_0089	1.527e-192	625.0	COG0013@1|root,COG0013@2|Bacteria,2NNYC@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474	DHHA1,tRNA-synt_2c,tRNA_SAD
SRD1_k127_2123356_0	926569.ANT_20420	1.427e-162	527.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi	200795|Chloroflexi	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRD1_k127_2123356_2	1499680.CCFE01000016_gene1164	8.702e-59	230.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,1ZAYB@1386|Bacillus	91061|Bacilli	S	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like	yabN	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
SRD1_k127_2123356_5	1267534.KB906754_gene3295	3.479e-14	76.0	2FCYS@1|root,3451F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2123356_3	861299.J421_5827	2.722e-50	193.0	COG3315@1|root,COG3315@2|Bacteria	2|Bacteria	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
SRD1_k127_2123356_4	404589.Anae109_2339	3.079e-49	192.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,2YVDX@29|Myxococcales	28221|Deltaproteobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
SRD1_k127_2123356_1	765420.OSCT_0934	1.233e-73	256.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi,375CT@32061|Chloroflexia	32061|Chloroflexia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
SRD1_k127_2139070_1	251221.35214981	6.589e-39	151.0	COG5516@1|root,COG5516@2|Bacteria	2|Bacteria	S	CGNR zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRD1_k127_2139070_2	1187851.A33M_1644	4.835e-10	71.0	2CIPC@1|root,2Z9HB@2|Bacteria,1R3W8@1224|Proteobacteria,2TST7@28211|Alphaproteobacteria	1187851.A33M_1644|-	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2139070_0	1382306.JNIM01000001_gene1384	5.899e-227	713.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRD1_k127_2146288_0	309801.trd_0496	2.896e-170	542.0	COG2513@1|root,COG2513@2|Bacteria,2GAB6@200795|Chloroflexi,27YTJ@189775|Thermomicrobia	189775|Thermomicrobia	G	Phosphoenolpyruvate phosphomutase	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
SRD1_k127_2146288_1	266117.Rxyl_2065	3.577e-92	312.0	COG0583@1|root,COG0583@2|Bacteria,2GK13@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRD1_k127_2154083_1	479434.Sthe_2670	1.516e-50	195.0	COG0842@1|root,COG0842@2|Bacteria,2G6II@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRD1_k127_2154083_0	700598.Niako_2090	3.768e-96	321.0	COG1131@1|root,COG1131@2|Bacteria,4NMN9@976|Bacteroidetes	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_2154083_2	1120950.KB892763_gene5546	1.698e-33	136.0	COG3877@1|root,COG3877@2|Bacteria,2IT3M@201174|Actinobacteria,4DVDP@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
SRD1_k127_216580_0	290397.Adeh_1613	2.893e-191	606.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRD1_k127_216580_7	1382356.JQMP01000003_gene1563	1.731e-33	143.0	COG1322@1|root,COG1322@2|Bacteria,2G8PC@200795|Chloroflexi,27Z4X@189775|Thermomicrobia	189775|Thermomicrobia	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRD1_k127_216580_10	370438.PTH_2823	3.121e-21	101.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,261R0@186807|Peptococcaceae	186801|Clostridia	F	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
SRD1_k127_216580_8	59538.XP_005983646.1	8.759e-32	133.0	COG0494@1|root,KOG3904@2759|Eukaryota,39R6U@33154|Opisthokonta	33154|Opisthokonta	L	metal ion binding	-	-	-	ko:K13355	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRD1_k127_216580_5	290397.Adeh_2760	6.44e-68	239.0	COG1028@1|root,COG1028@2|Bacteria,1MW46@1224|Proteobacteria,430ID@68525|delta/epsilon subdivisions,2WW1J@28221|Deltaproteobacteria,2YZPM@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD1_k127_216580_3	66373.JOFQ01000001_gene2005	1.916e-111	376.0	COG0657@1|root,COG0657@2|Bacteria,2I5U9@201174|Actinobacteria	201174|Actinobacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRD1_k127_216580_9	1007103.AFHW01000017_gene5757	1.163e-21	110.0	COG4430@1|root,COG4430@2|Bacteria,1TYVP@1239|Firmicutes,4I0UE@91061|Bacilli,26YIC@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
SRD1_k127_216580_1	1179773.BN6_32170	9.92e-163	525.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4DXBU@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRD1_k127_216580_4	1232410.KI421424_gene1794	5.547e-104	355.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria,43TSP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRD1_k127_216580_2	1379698.RBG1_1C00001G1061	1.113e-111	378.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRD1_k127_216580_6	929556.Solca_3729	5.275e-66	237.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRD1_k127_2208480_2	1463841.JOIR01000056_gene7	3.305e-17	87.0	29ACN@1|root,2ZXD4@2|Bacteria,2H1S0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2208480_1	685727.REQ_14820	1.516e-96	347.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FUTU@85025|Nocardiaceae	201174|Actinobacteria	K	activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC,TPR_12
SRD1_k127_2208480_0	981369.JQMJ01000004_gene2150	1.257e-99	337.0	28JU5@1|root,2Z9J8@2|Bacteria,2H3FR@201174|Actinobacteria,2NEF1@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2209205_3	357808.RoseRS_2474	7.705e-34	136.0	COG1131@1|root,COG1131@2|Bacteria,2G5YX@200795|Chloroflexi,3762X@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_2209205_0	880073.Calab_3769	1.077e-227	725.0	COG1770@1|root,COG1770@2|Bacteria,2NNMF@2323|unclassified Bacteria	2|Bacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRD1_k127_2209205_6	509190.Cseg_0307	0.0004156	47.0	COG5649@1|root,COG5649@2|Bacteria	2|Bacteria	E	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRD1_k127_2209205_4	1089544.KB912942_gene7293	4.707e-33	134.0	COG3945@1|root,COG3945@2|Bacteria,2I92G@201174|Actinobacteria	201174|Actinobacteria	S	deazaflavin-dependent nitroreductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRD1_k127_2209205_1	1283299.AUKG01000001_gene1430	2.948e-84	286.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,4CRAC@84995|Rubrobacteria	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRD1_k127_2209205_5	929556.Solca_0145	3.118e-19	89.0	2E5NA@1|root,330D3@2|Bacteria,4NUZF@976|Bacteroidetes,1IU4P@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4287)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
SRD1_k127_2209205_2	1463825.JNXC01000005_gene2508	7.698e-45	173.0	COG1708@1|root,COG1708@2|Bacteria,2IFWR@201174|Actinobacteria,4E40Z@85010|Pseudonocardiales	201174|Actinobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRD1_k127_226333_1	485913.Krac_2245	9.085e-88	297.0	COG0600@1|root,COG0600@2|Bacteria,2G8D1@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRD1_k127_226333_0	485913.Krac_2246	2.31e-122	400.0	COG1116@1|root,COG1116@2|Bacteria,2G892@200795|Chloroflexi	200795|Chloroflexi	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRD1_k127_226333_2	1122939.ATUD01000009_gene3090	4.787e-28	118.0	COG3290@1|root,COG3290@2|Bacteria,2GIRZ@201174|Actinobacteria,4CSF7@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,sCache_3_2
SRD1_k127_2268870_0	931627.MycrhDRAFT_5098	2.542e-75	263.0	COG1215@1|root,COG1215@2|Bacteria,2IBMN@201174|Actinobacteria,239CX@1762|Mycobacteriaceae	201174|Actinobacteria	MQ	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11
SRD1_k127_2268870_1	35754.JNYJ01000001_gene7477	5.035e-26	108.0	COG0451@1|root,COG0451@2|Bacteria,2I9T0@201174|Actinobacteria,4DA9R@85008|Micromonosporales	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRD1_k127_2283156_14	1206731.BAGB01000151_gene4170	5.165e-07	66.0	2B6XM@1|root,31ZKD@2|Bacteria,2H296@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2283156_9	1121946.AUAX01000019_gene7812	1.363e-54	224.0	COG2931@1|root,COG2931@2|Bacteria,2GR03@201174|Actinobacteria,4DM29@85008|Micromonosporales	201174|Actinobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,HemolysinCabind,Peptidase_M91,fn3
SRD1_k127_2283156_16	344747.PM8797T_10909	0.0002137	58.0	COG1357@1|root,COG1357@2|Bacteria,2J2VS@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2283156_0	1461694.ATO9_12480	2.801e-224	787.0	COG0771@1|root,COG2931@1|root,COG0771@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2V8V8@28211|Alphaproteobacteria,2PFGF@252301|Oceanicola	28211|Alphaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2283156_13	1232410.KI421412_gene336	4.335e-17	82.0	29SGJ@1|root,2ZKKB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2283156_15	1146883.BLASA_2870	3.161e-05	49.0	2C59E@1|root,2ZDAY@2|Bacteria	2|Bacteria	S	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRD1_k127_2283156_12	926569.ANT_02430	1.659e-25	121.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2283156_11	2002.JOEQ01000009_gene6562	1.04e-31	136.0	COG3485@1|root,COG3485@2|Bacteria,2GZGT@201174|Actinobacteria,4EIYW@85012|Streptosporangiales	201174|Actinobacteria	Q	protocatechuate 3,4-dioxygenase	pcaG	-	1.13.11.3	ko:K00448	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
SRD1_k127_2283156_3	1411123.JQNH01000001_gene2070	8.406e-103	338.0	COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,2TU2C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	protocatechuate 3,4-dioxygenase, beta subunit'	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
SRD1_k127_2283156_1	543632.JOJL01000042_gene4590	7.37e-183	582.0	COG0683@1|root,COG0683@2|Bacteria,2IBBY@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRD1_k127_2283156_5	1158292.JPOE01000005_gene189	3.038e-85	292.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,1KK0Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRD1_k127_2283156_6	1040983.AXAE01000001_gene2796	6.04e-85	299.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2U1ZT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRD1_k127_2283156_4	543632.JOJL01000042_gene4593	7.171e-101	337.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRD1_k127_2283156_2	1463917.JODC01000041_gene2953	5.91e-108	372.0	COG4177@1|root,COG4177@2|Bacteria	2|Bacteria	E	L-phenylalanine transmembrane transporter activity	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD1_k127_2283156_10	1156844.KB891842_gene7169	6.556e-33	136.0	COG1846@1|root,COG1846@2|Bacteria,2IB1S@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K22489	-	-	-	-	ko00000,ko03000	-	-	-	HTH_27,MarR,MarR_2
SRD1_k127_2283156_7	479434.Sthe_2711	1.198e-78	278.0	COG1335@1|root,COG1335@2|Bacteria,2G922@200795|Chloroflexi,27YMA@189775|Thermomicrobia	189775|Thermomicrobia	Q	Isochorismatase family	-	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SRD1_k127_2283156_8	485913.Krac_2436	1.193e-56	203.0	COG1541@1|root,COG1541@2|Bacteria,2G695@200795|Chloroflexi	200795|Chloroflexi	H	AMP-binding enzyme	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
SRD1_k127_2290924_0	1121423.JONT01000028_gene672	1.521e-73	271.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1UYB2@1239|Firmicutes,24AKI@186801|Clostridia,263E3@186807|Peptococcaceae	186801|Clostridia	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
SRD1_k127_2293573_4	292459.STH607	2.332e-25	110.0	COG0577@1|root,COG0577@2|Bacteria,1TUYK@1239|Firmicutes,24DGM@186801|Clostridia	186801|Clostridia	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRD1_k127_2293573_3	926569.ANT_07660	2.712e-62	229.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_2293573_8	58344.JOEL01000080_gene3460	0.0002845	49.0	COG3832@1|root,COG3832@2|Bacteria,2ISCU@201174|Actinobacteria	201174|Actinobacteria	S	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRD1_k127_2293573_5	1120973.AQXL01000073_gene1104	4.894e-18	91.0	COG1309@1|root,COG1309@2|Bacteria,1V5AJ@1239|Firmicutes,4HI7X@91061|Bacilli	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRD1_k127_2293573_0	1242864.D187_003103	3.831e-159	539.0	COG2409@1|root,COG2409@2|Bacteria,1R9Z8@1224|Proteobacteria	1224|Proteobacteria	S	MMPL family	ydfJ	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRD1_k127_2293573_2	479434.Sthe_0414	9.004e-78	292.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi,27XKY@189775|Thermomicrobia	189775|Thermomicrobia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
SRD1_k127_2293573_1	373903.Hore_12400	9.986e-129	436.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WABM@53433|Halanaerobiales	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD1_k127_2293573_7	1179773.BN6_55980	1.822e-10	73.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,2GK45@201174|Actinobacteria,4E417@85010|Pseudonocardiales	201174|Actinobacteria	Q	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Lactonase,TIG
SRD1_k127_2293573_6	1382306.JNIM01000001_gene717	1.533e-16	86.0	COG1102@1|root,COG1102@2|Bacteria,2G9BR@200795|Chloroflexi	200795|Chloroflexi	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
SRD1_k127_2297738_3	1121115.AXVN01000066_gene3221	1.016e-06	57.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,3Y0DF@572511|Blautia	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
SRD1_k127_2297738_2	1894.JOER01000009_gene8032	2.317e-30	133.0	COG0265@1|root,COG0265@2|Bacteria,2GJ15@201174|Actinobacteria	201174|Actinobacteria	O	PDZ DHR GLGF domain protein	sprJ	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRD1_k127_2297738_0	665952.HMPREF1015_02576	2.208e-119	407.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,1ZBP1@1386|Bacillus	91061|Bacilli	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRD1_k127_2297738_1	552811.Dehly_0061	1.274e-60	227.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi,34D5Y@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRD1_k127_2300901_0	292459.STH1579	6.952e-108	359.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,24BNG@186801|Clostridia	186801|Clostridia	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRD1_k127_2300901_1	469383.Cwoe_1592	7.55e-66	233.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0N@201174|Actinobacteria,4CPTH@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD1_k127_2300901_2	105420.BBPO01000059_gene3253	3.604e-38	150.0	COG1971@1|root,COG1971@2|Bacteria,2HSSZ@201174|Actinobacteria,2NMA9@228398|Streptacidiphilus	201174|Actinobacteria	P	Putative manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
SRD1_k127_2300901_3	182217.HCW_03645	6.072e-14	76.0	COG0789@1|root,COG0789@2|Bacteria,1N948@1224|Proteobacteria,42SGY@68525|delta/epsilon subdivisions,2YPH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	hspR	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRD1_k127_2304123_3	489825.LYNGBM3L_47380	1.424e-101	380.0	COG2931@1|root,COG3386@1|root,COG4447@1|root,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4447@2|Bacteria,1G7BP@1117|Cyanobacteria,1HCF5@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
SRD1_k127_2304123_7	314230.DSM3645_28792	4.801e-13	86.0	COG1357@1|root,COG1357@2|Bacteria,2J2VS@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2304123_8	1206731.BAGB01000151_gene4170	2.754e-08	70.0	2B6XM@1|root,31ZKD@2|Bacteria,2H296@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2304123_9	1280390.CBQR020000166_gene4413	1.084e-07	68.0	COG4733@1|root,COG4733@2|Bacteria,1TQB3@1239|Firmicutes,4HU7T@91061|Bacilli,26RV2@186822|Paenibacillaceae	91061|Bacilli	G	Cellulose 1,4-beta-cellobiosidase	bglC3	-	-	-	-	-	-	-	-	-	-	-	CBM_3,Glyco_hydro_48,fn3
SRD1_k127_2304123_4	1121946.AUAX01000035_gene6175	1.622e-81	287.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4D8Q5@85008|Micromonosporales	201174|Actinobacteria	K	transcriptional	cebR	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRD1_k127_2304123_6	401526.TcarDRAFT_2136	7.718e-15	83.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4H4XP@909932|Negativicutes	909932|Negativicutes	M	transglycosylase	ltg	-	-	-	-	-	-	-	-	-	-	-	SLT
SRD1_k127_2304123_5	1380390.JIAT01000010_gene3637	1.701e-57	217.0	COG1752@1|root,COG1752@2|Bacteria,2IB0F@201174|Actinobacteria,4CR75@84995|Rubrobacteria	84995|Rubrobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SRD1_k127_2304123_0	710421.Mycch_1189	0.0	1168.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,235F6@1762|Mycobacteriaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase	adhE	-	1.1.1.1,1.2.1.10,1.2.1.81	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
SRD1_k127_2304123_2	653733.Selin_1410	3.099e-126	429.0	COG1022@1|root,COG1022@2|Bacteria	2|Bacteria	I	Amp-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRD1_k127_2304123_1	1283299.AUKG01000002_gene5335	1.042e-235	749.0	COG0058@1|root,COG0058@2|Bacteria,2GIVZ@201174|Actinobacteria,4CPGW@84995|Rubrobacteria	84995|Rubrobacteria	G	Protein of unknown function (DUF3417)	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRD1_k127_2312085_2	485913.Krac_12470	1.367e-102	342.0	COG1788@1|root,COG1788@2|Bacteria,2G6IM@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRD1_k127_2312085_1	1192034.CAP_5586	9.039e-123	417.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,2YVCP@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0976	Chorismate_synt
SRD1_k127_2312085_4	523850.TON_1169	1.161e-10	74.0	COG1011@1|root,arCOG02291@2157|Archaea,2XUJR@28890|Euryarchaeota,2431M@183968|Thermococci	183968|Thermococci	S	haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRD1_k127_2312085_3	1209989.TepiRe1_0459	2.153e-47	186.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,42J1J@68295|Thermoanaerobacterales	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4,1.17.1.5	ko:K00087,ko:K20447	ko00230,ko00760,ko01100,ko01120,map00230,map00760,map01100,map01120	M00546	R01720,R01768,R02103	RC00143,RC00589	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRD1_k127_2312085_0	1382306.JNIM01000001_gene1023	1.424e-242	766.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRD1_k127_2312656_1	1304865.JAGF01000001_gene1632	2.075e-40	153.0	COG3177@1|root,COG3177@2|Bacteria,2ICFW@201174|Actinobacteria	201174|Actinobacteria	K	PFAM filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRD1_k127_2312656_2	1089544.KB912942_gene5898	3.031e-08	56.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4E8W0@85010|Pseudonocardiales	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRD1_k127_2312656_0	1033743.CAES01000055_gene4783	1.466e-152	492.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli,2726Z@186822|Paenibacillaceae	91061|Bacilli	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRD1_k127_2321578_1	525368.HMPREF0591_2576	4.975e-24	106.0	COG0682@1|root,COG0682@2|Bacteria,2GP8C@201174|Actinobacteria,235FI@1762|Mycobacteriaceae	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT
SRD1_k127_2321578_0	1050202.KB913024_gene3614	1.409e-73	260.0	COG1964@1|root,COG1964@2|Bacteria,2I9RQ@201174|Actinobacteria	201174|Actinobacteria	Q	Radical SAM	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Methyltransf_11,Radical_SAM
SRD1_k127_2325131_2	509635.N824_03515	6.423e-105	355.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1IQ4X@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRD1_k127_2325131_4	1157490.EL26_10370	6.928e-17	94.0	COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,1VHJ0@1239|Firmicutes,4HRK1@91061|Bacilli,278VW@186823|Alicyclobacillaceae	91061|Bacilli	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,TPR_12,TPR_7,TPR_8
SRD1_k127_2325131_3	1111069.TCCBUS3UF1_16010	1.537e-62	231.0	COG0077@1|root,COG0077@2|Bacteria,1WIGR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
SRD1_k127_2325131_0	1121472.AQWN01000001_gene273	9.731e-138	450.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,260GB@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRD1_k127_2325131_1	479434.Sthe_1555	1.65e-134	435.0	COG0059@1|root,COG0059@2|Bacteria,2G5NP@200795|Chloroflexi,27XV8@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRD1_k127_2342106_1	264732.Moth_0850	1.233e-89	302.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,42EUU@68295|Thermoanaerobacterales	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRD1_k127_2342106_0	1382306.JNIM01000001_gene41	8.247e-106	358.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRD1_k127_2389128_2	525903.Taci_1265	1.041e-43	168.0	COG0325@1|root,COG0325@2|Bacteria,3TB2D@508458|Synergistetes	508458|Synergistetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRD1_k127_2389128_4	667014.Thein_1772	1.066e-14	76.0	COG0762@1|root,COG0762@2|Bacteria,2GHYF@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRD1_k127_2389128_0	926550.CLDAP_37140	5.257e-278	884.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRD1_k127_2389128_3	204669.Acid345_1860	1.287e-20	98.0	COG0597@1|root,COG0597@2|Bacteria,3Y55H@57723|Acidobacteria,2JJN7@204432|Acidobacteriia	204432|Acidobacteriia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRD1_k127_2389128_1	477974.Daud_0949	1.761e-61	227.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,2607F@186807|Peptococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRD1_k127_2403851_3	316274.Haur_1180	3.572e-23	104.0	COG1653@1|root,COG1653@2|Bacteria,2G8AR@200795|Chloroflexi,376NE@32061|Chloroflexia	32061|Chloroflexia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1
SRD1_k127_2403851_1	102129.Lepto7375DRAFT_3892	1.564e-82	289.0	COG1175@1|root,COG1175@2|Bacteria,1G3BG@1117|Cyanobacteria,1H8SB@1150|Oscillatoriales	1117|Cyanobacteria	G	COG1175 ABC-type sugar transport systems permease components	-	-	-	ko:K10233	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRD1_k127_2403851_0	889378.Spiaf_2494	1.355e-102	341.0	COG0395@1|root,COG0395@2|Bacteria,2J5Z6@203691|Spirochaetes	203691|Spirochaetes	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119,ko:K10234	ko02010,map02010	M00196,M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28,3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRD1_k127_2403851_2	324602.Caur_1110	4.617e-43	181.0	COG1472@1|root,COG1472@2|Bacteria,2G8JU@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRD1_k127_2411512_0	1380370.JIBA01000003_gene2738	8.118e-53	202.0	2DQWK@1|root,3393J@2|Bacteria,2IEMK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2411512_4	1122998.AUHZ01000001_gene1833	6.301e-14	81.0	COG4585@1|root,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,4DUSB@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRD1_k127_2411512_1	869210.Marky_1576	2.813e-41	162.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD1_k127_2411512_3	396588.Tgr7_1788	1.225e-25	113.0	COG1714@1|root,COG1714@2|Bacteria,1N1XF@1224|Proteobacteria,1SDY3@1236|Gammaproteobacteria,1WZR8@135613|Chromatiales	135613|Chromatiales	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRD1_k127_2411512_6	1089553.Tph_c05480	8.437e-10	69.0	COG3745@1|root,COG3745@2|Bacteria,1V5FZ@1239|Firmicutes,24I7V@186801|Clostridia,42H14@68295|Thermoanaerobacterales	186801|Clostridia	U	Flp pilus assembly protein RcpC/CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
SRD1_k127_2411512_7	9739.XP_004324835.1	9.223e-10	71.0	COG0664@1|root,KOG1113@2759|Eukaryota,38GS1@33154|Opisthokonta,3BBF2@33208|Metazoa,3CS4Z@33213|Bilateria,486N9@7711|Chordata,48XS9@7742|Vertebrata,3J9XA@40674|Mammalia,4J15Y@91561|Cetartiodactyla	33208|Metazoa	T	cAMP-dependent protein kinase type I-beta regulatory	PRKAR1B	GO:0000166,GO:0001932,GO:0001933,GO:0001934,GO:0003008,GO:0003014,GO:0003091,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005929,GO:0005952,GO:0006464,GO:0006468,GO:0006469,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0007596,GO:0007599,GO:0007610,GO:0007611,GO:0008150,GO:0008152,GO:0008283,GO:0008603,GO:0009611,GO:0009653,GO:0009719,GO:0009725,GO:0009887,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0016310,GO:0017076,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019538,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0030104,GO:0030234,GO:0030291,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032870,GO:0032991,GO:0033673,GO:0033674,GO:0033762,GO:0034199,GO:0034236,GO:0036094,GO:0036211,GO:0042060,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042592,GO:0042995,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043412,GO:0043434,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044441,GO:0044444,GO:0044463,GO:0044464,GO:0045859,GO:0045860,GO:0045936,GO:0045937,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048731,GO:0048856,GO:0048871,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050817,GO:0050877,GO:0050878,GO:0050890,GO:0050891,GO:0050896,GO:0051018,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051246,GO:0051247,GO:0051248,GO:0051338,GO:0051347,GO:0051348,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071310,GO:0071375,GO:0071377,GO:0071417,GO:0071495,GO:0071704,GO:0071900,GO:0071901,GO:0080090,GO:0097159,GO:0097367,GO:0097546,GO:0098772,GO:0120025,GO:0120038,GO:1901265,GO:1901363,GO:1901564,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:2000479,GO:2000480	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	RIIa,cNMP_binding
SRD1_k127_2411512_5	1385511.N783_03890	5.801e-12	78.0	COG0455@1|root,COG0455@2|Bacteria,1UMT9@1239|Firmicutes,4HJT8@91061|Bacilli	91061|Bacilli	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
SRD1_k127_2411512_8	1029824.AFID01000005_gene746	6.994e-07	61.0	COG1413@1|root,COG1413@2|Bacteria,2INKI@201174|Actinobacteria,1WAYG@1268|Micrococcaceae	201174|Actinobacteria	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRD1_k127_2411512_2	391613.RTM1035_14532	5.652e-36	144.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2TRNT@28211|Alphaproteobacteria,46NNN@74030|Roseovarius	28211|Alphaproteobacteria	U	Type II IV secretion system protein, TadA subfamily	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRD1_k127_2419805_0	479434.Sthe_0904	6.959e-47	183.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD1_k127_2419805_1	479434.Sthe_2654	1.2e-19	102.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZW@200795|Chloroflexi,27YUJ@189775|Thermomicrobia	189775|Thermomicrobia	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRD1_k127_2428641_2	1173027.Mic7113_4278	7.054e-32	130.0	COG0520@1|root,COG0520@2|Bacteria,1G5MD@1117|Cyanobacteria,1HEDZ@1150|Oscillatoriales	1117|Cyanobacteria	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRD1_k127_2428641_0	1122604.JONR01000028_gene3489	2.063e-69	257.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.123	ko:K05991	-	-	-	-	ko00000,ko01000	-	GH5	-	Cellulase
SRD1_k127_2428641_1	1463920.JOGB01000016_gene5490	8.061e-37	159.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter, ATP-binding protein	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRD1_k127_244258_2	1382356.JQMP01000003_gene2082	2.529e-70	243.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi,27XUN@189775|Thermomicrobia	189775|Thermomicrobia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRD1_k127_244258_3	667014.Thein_1233	2.437e-21	97.0	COG0718@1|root,COG0718@2|Bacteria,2GHY9@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRD1_k127_244258_1	643648.Slip_0034	5.836e-88	308.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,42JK4@68298|Syntrophomonadaceae	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRD1_k127_244258_5	7217.FBpp0121428	2.705e-09	67.0	COG0558@1|root,KOG1617@2759|Eukaryota,38BTA@33154|Opisthokonta,3BFWV@33208|Metazoa,3CWJD@33213|Bilateria,41WTJ@6656|Arthropoda,3SHCW@50557|Insecta,451GC@7147|Diptera,45T7P@7214|Drosophilidae	33208|Metazoa	I	Phosphotransferase activity, for other substituted phosphate groups. It is involved in the biological process described with phospholipid biosynthetic process	CRLS1	GO:0001101,GO:0003674,GO:0003824,GO:0003841,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0007006,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0010243,GO:0014070,GO:0016020,GO:0016043,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0030572,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032048,GO:0032049,GO:0033993,GO:0034641,GO:0034654,GO:0036148,GO:0042127,GO:0042171,GO:0042221,GO:0042391,GO:0042493,GO:0043200,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043337,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046034,GO:0046390,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0046683,GO:0047144,GO:0050789,GO:0050794,GO:0050896,GO:0051881,GO:0055086,GO:0061024,GO:0065007,GO:0065008,GO:0071617,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:0097066,GO:0097068,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901698,GO:1901700,GO:1904386,GO:1905711	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRD1_k127_244258_0	1128421.JAGA01000002_gene1247	7.285e-91	328.0	COG0744@1|root,COG0744@2|Bacteria	2|Bacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
SRD1_k127_244258_4	1279009.ADICEAN_01542	6.159e-12	77.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,47KJD@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRD1_k127_24481_7	1407650.BAUB01000004_gene982	4.446e-06	59.0	COG0510@1|root,COG0510@2|Bacteria,1G6EX@1117|Cyanobacteria	1117|Cyanobacteria	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRD1_k127_24481_6	1121874.KB892380_gene1765	8.725e-08	61.0	COG2340@1|root,COG3583@1|root,COG2340@2|Bacteria,COG3583@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	CAP,G5,LysM,Peptidase_M23
SRD1_k127_24481_1	926550.CLDAP_37440	7.747e-96	340.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
SRD1_k127_24481_0	479434.Sthe_1953	4.943e-127	424.0	COG0380@1|root,COG0380@2|Bacteria,2G6F8@200795|Chloroflexi,27XTV@189775|Thermomicrobia	189775|Thermomicrobia	G	Glycosyltransferase family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRD1_k127_24481_5	646529.Desaci_0708	7.915e-12	72.0	COG0762@1|root,COG0762@2|Bacteria,1VN1M@1239|Firmicutes,24X1E@186801|Clostridia,265M7@186807|Peptococcaceae	186801|Clostridia	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
SRD1_k127_24481_3	1408424.JHYI01000011_gene1350	3.786e-17	96.0	COG3291@1|root,COG3291@2|Bacteria,1V0FC@1239|Firmicutes,4HES3@91061|Bacilli,1ZE9N@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906
SRD1_k127_24481_2	926550.CLDAP_37440	3.962e-94	335.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
SRD1_k127_24481_4	263358.VAB18032_19320	6.42e-17	89.0	COG1595@1|root,COG1595@2|Bacteria,2GKDD@201174|Actinobacteria,4DDN5@85008|Micromonosporales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_2460539_4	1449346.JQMO01000003_gene2639	2.048e-09	66.0	COG0265@1|root,COG0265@2|Bacteria,2GJJ3@201174|Actinobacteria,2M53I@2063|Kitasatospora	201174|Actinobacteria	O	PDZ domain (Also known as DHR or GLGF)	pepA	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRD1_k127_2460539_1	1121272.KB903283_gene5019	8.586e-120	410.0	COG1215@1|root,COG1215@2|Bacteria,2GKFI@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
SRD1_k127_2460539_2	1283299.AUKG01000001_gene2533	2.126e-89	310.0	COG0477@1|root,COG2814@2|Bacteria,2GJPT@201174|Actinobacteria,4CPPA@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRD1_k127_2460539_0	1123389.ATXJ01000001_gene676	1.946e-219	689.0	COG1012@1|root,COG1012@2|Bacteria,1WJFH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD1_k127_2460539_3	1382306.JNIM01000001_gene2761	2.167e-69	237.0	COG1809@1|root,COG1809@2|Bacteria	2|Bacteria	S	phosphosulfolactate synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	ComA
SRD1_k127_2471185_4	1122925.KB895376_gene763	1.788e-18	89.0	COG0697@1|root,COG0697@2|Bacteria,1UYSM@1239|Firmicutes,4HFBU@91061|Bacilli,26SAB@186822|Paenibacillaceae	91061|Bacilli	EG	of the drug metabolite transporter (DMT) superfamily	yoaV5	-	-	-	-	-	-	-	-	-	-	-	EamA
SRD1_k127_2471185_3	2325.TKV_c11470	2.022e-37	145.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,42GII@68295|Thermoanaerobacterales	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRD1_k127_2471185_0	357808.RoseRS_3200	1.955e-86	308.0	COG0825@1|root,COG0825@2|Bacteria,2G7S3@200795|Chloroflexi,376V0@32061|Chloroflexia	32061|Chloroflexia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SRD1_k127_2471185_1	243230.DR_1215	1.817e-63	233.0	COG0777@1|root,COG0777@2|Bacteria,1WIB7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRD1_k127_2471185_2	1382306.JNIM01000001_gene1709	7.166e-49	178.0	COG1028@1|root,COG1028@2|Bacteria,2G5KB@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD1_k127_2476108_0	1329516.JPST01000015_gene758	1.17e-78	273.0	COG0842@1|root,COG0842@2|Bacteria,1VI3K@1239|Firmicutes,4IPII@91061|Bacilli	91061|Bacilli	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
SRD1_k127_2476108_2	1444309.JAQG01000057_gene4902	8.149e-25	108.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,26WUX@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRD1_k127_2476108_1	243231.GSU3077	9.004e-76	267.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2WJ8J@28221|Deltaproteobacteria,43TQT@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRD1_k127_2528772_4	644283.Micau_3308	1.552e-15	86.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4D9C3@85008|Micromonosporales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRD1_k127_2528772_1	523845.AQXV01000040_gene1689	3.482e-127	427.0	arCOG12080@1|root,arCOG12080@2157|Archaea,2Y30S@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2528772_5	313606.M23134_08441	0.0004154	50.0	2DCS6@1|root,2ZF4U@2|Bacteria,4P8QB@976|Bacteroidetes,47X2E@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2528772_3	315750.BPUM_0171	5.891e-44	163.0	COG0251@1|root,COG0251@2|Bacteria,1V6HQ@1239|Firmicutes,4HJ32@91061|Bacilli,1ZFSF@1386|Bacillus	91061|Bacilli	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRD1_k127_2528772_0	479435.Kfla_0362	5.275e-157	508.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria,4DPW1@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD1_k127_2528772_2	1306406.ASHX01000001_gene888	1.343e-122	400.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	sigG	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	NTF2,Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRD1_k127_2534031_0	1123023.JIAI01000007_gene1962	2.339e-163	518.0	COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria,4DXJB@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SRD1_k127_2534031_3	591157.SSLG_04686	4.181e-31	134.0	COG1793@1|root,COG1793@2|Bacteria,2IA2C@201174|Actinobacteria	201174|Actinobacteria	L	DNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_M
SRD1_k127_2534031_1	1122939.ATUD01000003_gene3528	2.734e-70	249.0	COG2514@1|root,COG2514@2|Bacteria,2GN1X@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRD1_k127_2534031_2	1051632.TPY_3590	1.27e-67	234.0	COG0247@1|root,COG0479@1|root,COG2181@1|root,COG0247@2|Bacteria,COG0479@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SRD1_k127_2550026_5	1095750.HMPREF9970_2962	9.19e-40	153.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,1HW31@1164882|Lachnoanaerobaculum	186801|Clostridia	I	BadF/BadG/BcrA/BcrD ATPase family	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRD1_k127_2550026_1	1379698.RBG1_1C00001G0907	6.235e-133	439.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	bamA	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788	3.7.1.21	ko:K07539,ko:K18570	ko00332,ko00362,ko01100,ko01120,ko01130,ko01220,map00332,map00362,map01100,map01120,map01130,map01220	M00541	R05593,R05594,R10696,R10750	RC01430,RC01431,RC03237,RC03270	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD1_k127_2550026_4	266265.Bxe_C1040	5.373e-44	174.0	COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,2VHY6@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRD1_k127_2550026_6	766499.C357_10879	1.701e-36	157.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,2TUZ8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRD1_k127_2550026_3	28042.GU90_06610	3.129e-75	261.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4E1KU@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059,ko:K07535	ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220	M00083,M00540,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05582,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00154	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD1_k127_2550026_7	1380390.JIAT01000009_gene1645	8.391e-32	141.0	COG0346@1|root,COG0346@2|Bacteria,2IQE0@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD1_k127_2550026_2	926569.ANT_28310	7.813e-112	371.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRD1_k127_2550026_0	595460.RRSWK_03757	7.331e-185	588.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,2IYDT@203682|Planctomycetes	203682|Planctomycetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
SRD1_k127_2586831_1	1515615.HQ41_06750	4.992e-44	181.0	COG0330@1|root,COG0330@2|Bacteria,4NH8V@976|Bacteroidetes,2FQPC@200643|Bacteroidia,22Z0Q@171551|Porphyromonadaceae	976|Bacteroidetes	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRD1_k127_2586831_2	158190.SpiGrapes_0105	7.235e-19	93.0	COG1585@1|root,COG1585@2|Bacteria	2|Bacteria	OU	cellular response to DNA damage stimulus	nfeD	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
SRD1_k127_2586831_0	379066.GAU_2304	3.399e-61	230.0	COG3595@1|root,COG3595@2|Bacteria,1ZTJA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRD1_k127_2651192_14	521045.Kole_0915	2.932e-15	88.0	COG0745@1|root,COG0745@2|Bacteria,2GCXG@200918|Thermotogae	200918|Thermotogae	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_2651192_10	749414.SBI_05880	1.742e-33	148.0	COG2197@1|root,COG3829@1|root,COG4585@1|root,COG2197@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,2IAG1@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,Response_reg
SRD1_k127_2651192_12	749414.SBI_05879	2.142e-21	98.0	COG2197@1|root,COG2197@2|Bacteria,2I126@201174|Actinobacteria	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD1_k127_2651192_13	1229780.BN381_100137	1.587e-19	97.0	COG2353@1|root,COG2353@2|Bacteria,2IM4N@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRD1_k127_2651192_15	471857.Svir_13680	0.0006305	51.0	COG0640@1|root,COG0640@2|Bacteria,2IMSD@201174|Actinobacteria,4E4SS@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory protein, arsR family	smtB	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0044212,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K22298	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRD1_k127_2651192_0	1236902.ANAS01000013_gene1352	1.682e-215	688.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,4EI8Q@85012|Streptosporangiales	201174|Actinobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRD1_k127_2651192_4	469383.Cwoe_3472	1.42e-82	289.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria	201174|Actinobacteria	O	Thioredoxin	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
SRD1_k127_2651192_8	1206720.BAFQ01000196_gene4981	3.066e-50	197.0	COG2267@1|root,COG2267@2|Bacteria,2I3PK@201174|Actinobacteria,4G14X@85025|Nocardiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRD1_k127_2651192_5	1283299.AUKG01000001_gene1990	1.454e-75	257.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria,4CSPT@84995|Rubrobacteria	84995|Rubrobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRD1_k127_2651192_6	479434.Sthe_1767	1.077e-57	213.0	COG1277@1|root,COG1277@2|Bacteria,2GBGK@200795|Chloroflexi,27YD7@189775|Thermomicrobia	189775|Thermomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRD1_k127_2651192_2	479434.Sthe_1768	3.02e-93	315.0	COG1131@1|root,COG1131@2|Bacteria,2G5QI@200795|Chloroflexi,27XXC@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_2651192_1	1961.JOAK01000005_gene24	1.464e-95	329.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRD1_k127_2651192_3	1121272.KB903290_gene4729	7.071e-84	283.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,4DEM5@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRD1_k127_2651192_7	105422.BBPM01000067_gene406	9.868e-51	187.0	COG3593@1|root,COG3593@2|Bacteria,2GMN5@201174|Actinobacteria,2NJ3U@228398|Streptacidiphilus	201174|Actinobacteria	L	DNA synthesis involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2651192_11	877418.ATWV01000014_gene2783	7.163e-31	134.0	COG0739@1|root,COG0739@2|Bacteria,2J6RF@203691|Spirochaetes	203691|Spirochaetes	M	LysM domain M23 M37 peptidase domain protein	nlpD	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
SRD1_k127_2651192_9	1906.SFRA_05175	4.476e-48	191.0	COG0604@1|root,COG0604@2|Bacteria,2GK7Y@201174|Actinobacteria	201174|Actinobacteria	C	NADPH quinone	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD1_k127_266414_2	1415166.NONO_c66890	2.147e-10	66.0	COG4818@1|root,COG4818@2|Bacteria,2HHYG@201174|Actinobacteria,4G1PM@85025|Nocardiaceae	201174|Actinobacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
SRD1_k127_266414_0	356851.JOAN01000001_gene3660	1.358e-70	251.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4D8JM@85008|Micromonosporales	201174|Actinobacteria	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRD1_k127_266414_1	1123508.JH636446_gene6211	2.497e-64	229.0	COG0177@1|root,COG0177@2|Bacteria,2IYYT@203682|Planctomycetes	203682|Planctomycetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRD1_k127_266414_3	479433.Caci_9015	6.381e-05	46.0	COG1610@1|root,COG1610@2|Bacteria,2IFFJ@201174|Actinobacteria	201174|Actinobacteria	S	GatB YqeY	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRD1_k127_2680396_1	525904.Tter_1371	3.154e-106	360.0	COG0505@1|root,COG0505@2|Bacteria,2NNMS@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955,ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383	CPSase_sm_chain,GATase
SRD1_k127_2680396_5	1236902.ANAS01000015_gene595	7.857e-55	200.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,4EIM2@85012|Streptosporangiales	201174|Actinobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRD1_k127_2680396_0	40149.OMERI10G01490.1	5.364e-118	387.0	COG0458@1|root,KOG0370@2759|Eukaryota,37MJ1@33090|Viridiplantae,3GGQ1@35493|Streptophyta,3KQ6H@4447|Liliopsida,3I5GI@38820|Poales	35493|Streptophyta	EF	Belongs to the ATCase OTCase family	PYRB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009267,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009987,GO:0009991,GO:0016036,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0034654,GO:0042594,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRD1_k127_2680396_4	1123508.JH636439_gene1180	1.845e-63	227.0	COG4555@1|root,COG4555@2|Bacteria,2IY7K@203682|Planctomycetes	203682|Planctomycetes	CP	ABC transporter (ATP-binding protein)-putative sodium extrusion ABC transporter	-	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
SRD1_k127_2680396_6	1340493.JNIF01000003_gene2271	1.936e-33	146.0	COG1668@1|root,COG1668@2|Bacteria,3Y8H3@57723|Acidobacteria	57723|Acidobacteria	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
SRD1_k127_2680396_2	263358.VAB18032_29841	1.588e-100	337.0	COG3570@1|root,COG3570@2|Bacteria,2GNSH@201174|Actinobacteria,4DFH1@85008|Micromonosporales	201174|Actinobacteria	V	aminoglycoside hydroxyurea antibiotic resistance kinase	aph2	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
SRD1_k127_2680396_3	526225.Gobs_0929	2.995e-70	243.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4ES7N@85013|Frankiales	201174|Actinobacteria	I	Belongs to the thiolase family	fadA2	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRD1_k127_2682660_0	404589.Anae109_2572	1.264e-71	250.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,42ZZ6@68525|delta/epsilon subdivisions,2WV5A@28221|Deltaproteobacteria,2YZAW@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRD1_k127_2682660_1	477641.MODMU_0075	6.905e-14	81.0	2BZ6B@1|root,336KR@2|Bacteria,2IQEV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2725896_0	42256.RradSPS_0573	0.0	1784.0	COG5013@1|root,COG5013@2|Bacteria,2GKZU@201174|Actinobacteria,4CRPX@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding,Nitr_red_alph_N
SRD1_k127_2725896_1	469383.Cwoe_1490	8.609e-156	494.0	COG1140@1|root,COG1140@2|Bacteria,2GJ8P@201174|Actinobacteria,4CRN0@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitrate reductase beta subunit	-	-	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Fer4_11,Nitr_red_bet_C
SRD1_k127_2745708_0	573061.Clocel_1358	3.853e-44	182.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,36EHU@31979|Clostridiaceae	186801|Clostridia	E	Family 5	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRD1_k127_2745708_1	479434.Sthe_3181	2.561e-22	100.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,27Y2Q@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRD1_k127_281443_8	211114.JOEF01000002_gene4088	1.653e-15	77.0	COG5516@1|root,COG5516@2|Bacteria,2IFNZ@201174|Actinobacteria,4E4QJ@85010|Pseudonocardiales	201174|Actinobacteria	S	CGNR zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRD1_k127_281443_3	525904.Tter_2236	9.575e-88	300.0	COG1975@1|root,COG1975@2|Bacteria,2NPTS@2323|unclassified Bacteria	2|Bacteria	O	XdhC and CoxI family	pucA	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRD1_k127_281443_2	765420.OSCT_2362	6.858e-99	340.0	COG3552@1|root,COG3552@2|Bacteria,2G5IW@200795|Chloroflexi,3769V@32061|Chloroflexia	32061|Chloroflexia	S	SMART von Willebrand factor, type A	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRD1_k127_281443_1	1382356.JQMP01000004_gene230	1.299e-107	357.0	COG0714@1|root,COG0714@2|Bacteria,2G5WI@200795|Chloroflexi,27Y33@189775|Thermomicrobia	189775|Thermomicrobia	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRD1_k127_281443_4	1313172.YM304_33320	1.106e-76	269.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4CMQN@84992|Acidimicrobiia	84992|Acidimicrobiia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRD1_k127_281443_0	1382356.JQMP01000004_gene228	1.379e-257	815.0	COG1529@1|root,COG1529@2|Bacteria,2G608@200795|Chloroflexi,27XWN@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRD1_k127_281443_5	1382356.JQMP01000004_gene227	2.973e-74	254.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi,27XMB@189775|Thermomicrobia	189775|Thermomicrobia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRD1_k127_281443_7	1194972.MVAC_04777	1.812e-34	142.0	COG3427@1|root,COG3427@2|Bacteria,2GKTQ@201174|Actinobacteria,234VG@1762|Mycobacteriaceae	201174|Actinobacteria	S	carbon monoxide dehydrogenase subunit G	-	-	-	-	-	-	-	-	-	-	-	-	COXG
SRD1_k127_281443_6	357808.RoseRS_3083	2.505e-53	198.0	COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi,377YI@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRD1_k127_2816635_1	1382306.JNIM01000001_gene4122	2.185e-29	123.0	COG0613@1|root,COG0613@2|Bacteria,2G74N@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
SRD1_k127_2816635_0	247633.GP2143_07964	1.469e-145	478.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria,1J5JZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	alkK	-	6.2.1.44	ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRD1_k127_2837748_1	370438.PTH_2734	3.448e-48	187.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,260S2@186807|Peptococcaceae	186801|Clostridia	GK	pfam rok	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
SRD1_k127_2837748_2	867845.KI911784_gene2002	2.904e-18	99.0	COG1247@1|root,COG1670@1|root,COG1247@2|Bacteria,COG1670@2|Bacteria,2GA8C@200795|Chloroflexi	200795|Chloroflexi	JM	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD1_k127_2837748_3	591159.ACEZ01000155_gene4462	4.649e-13	74.0	2BC4Q@1|root,325PH@2|Bacteria,2HAXH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2837748_0	1144275.COCOR_05004	1.91e-68	251.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,42P5X@68525|delta/epsilon subdivisions,2WIQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRD1_k127_2837748_4	765420.OSCT_2798	2.578e-06	49.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi,3770N@32061|Chloroflexia	32061|Chloroflexia	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRD1_k127_2983127_0	290397.Adeh_0990	3.896e-98	326.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,438SC@68525|delta/epsilon subdivisions,2X3Z4@28221|Deltaproteobacteria,2YXNG@29|Myxococcales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRD1_k127_2983127_1	316274.Haur_2553	8.271e-22	99.0	COG0705@1|root,COG0705@2|Bacteria,2G6J5@200795|Chloroflexi,375V4@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRD1_k127_2988895_3	1120949.KB903326_gene3139	1.713e-58	214.0	COG0346@1|root,COG0346@2|Bacteria,2IG0S@201174|Actinobacteria,4DED6@85008|Micromonosporales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD1_k127_2988895_2	1120949.KB903326_gene3140	4.718e-60	210.0	COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria,4DMVC@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRD1_k127_2988895_4	1449976.KALB_5609	9.918e-55	196.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4E43G@85010|Pseudonocardiales	201174|Actinobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRD1_k127_2988895_5	227882.SAV_3757	9.947e-18	88.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRD1_k127_2988895_1	1128421.JAGA01000004_gene2690	1.635e-72	252.0	COG0500@1|root,COG2226@2|Bacteria,2NP8K@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRD1_k127_2988895_0	485913.Krac_6506	2.502e-116	383.0	COG1793@1|root,COG1793@2|Bacteria,2G92J@200795|Chloroflexi	200795|Chloroflexi	L	PFAM ATP dependent DNA ligase domain protein	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRD1_k127_2990640_3	1128421.JAGA01000002_gene963	3.025e-05	55.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
SRD1_k127_2990640_1	1382306.JNIM01000001_gene942	1.89e-95	330.0	COG0508@1|root,COG0508@2|Bacteria,2G619@200795|Chloroflexi	200795|Chloroflexi	C	Catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRD1_k127_2990640_0	525904.Tter_0091	1.665e-123	413.0	COG0022@1|root,COG0022@2|Bacteria,2NNQZ@2323|unclassified Bacteria	2|Bacteria	C	Transketolase, pyrimidine binding domain	pdhB	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRD1_k127_2990640_2	525904.Tter_0090	5.103e-54	195.0	COG1071@1|root,COG1071@2|Bacteria,2NQC2@2323|unclassified Bacteria	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRD1_k127_2996723_16	1123284.KB899043_gene411	3.857e-15	81.0	2CH44@1|root,32S57@2|Bacteria,1VCKH@1239|Firmicutes,4HKXX@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2996723_10	1463825.JNXC01000004_gene4288	1.028e-35	147.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,4E21F@85010|Pseudonocardiales	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRD1_k127_2996723_15	7739.XP_002594092.1	2.091e-18	93.0	COG0251@1|root,KOG2317@2759|Eukaryota,3A5RT@33154|Opisthokonta,3BQRB@33208|Metazoa,3D86F@33213|Bilateria,48E1Q@7711|Chordata	33208|Metazoa	J	xenon atom binding	HRSP12	GO:0001505,GO:0001655,GO:0001822,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005504,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005829,GO:0006082,GO:0006139,GO:0006417,GO:0006457,GO:0006520,GO:0006544,GO:0006566,GO:0006567,GO:0006725,GO:0006807,GO:0007049,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008150,GO:0008152,GO:0008285,GO:0008289,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016054,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0017144,GO:0017148,GO:0019222,GO:0019239,GO:0019518,GO:0019752,GO:0022402,GO:0030323,GO:0030324,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031974,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0033293,GO:0033993,GO:0034248,GO:0034249,GO:0034641,GO:0035295,GO:0036041,GO:0036094,GO:0042127,GO:0042133,GO:0042221,GO:0042579,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046872,GO:0046914,GO:0046983,GO:0048513,GO:0048519,GO:0048523,GO:0048731,GO:0048856,GO:0050678,GO:0050680,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0060322,GO:0060541,GO:0065007,GO:0065008,GO:0070013,GO:0070314,GO:0071704,GO:0072001,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902074,GO:1904012,GO:1904013,GO:2000112,GO:2000113	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRD1_k127_2996723_13	1298867.AUES01000130_gene725	6.774e-25	112.0	COG1309@1|root,COG1309@2|Bacteria,1R67Z@1224|Proteobacteria,2VF1G@28211|Alphaproteobacteria,3JUFF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD1_k127_2996723_5	1122611.KB903940_gene1874	1.83e-78	274.0	COG2207@1|root,COG2207@2|Bacteria,2IHD7@201174|Actinobacteria,4ENEN@85012|Streptosporangiales	201174|Actinobacteria	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
SRD1_k127_2996723_1	1386089.N865_16085	1.468e-151	493.0	COG0477@1|root,COG2814@2|Bacteria,2I3MJ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
SRD1_k127_2996723_11	1087481.AGFX01000020_gene2342	1.301e-29	121.0	COG0640@1|root,COG0640@2|Bacteria,1V6CU@1239|Firmicutes,4HJ7N@91061|Bacilli,26YN7@186822|Paenibacillaceae	91061|Bacilli	K	ArsR family transcriptional regulator	arsR9	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRD1_k127_2996723_14	1122603.ATVI01000010_gene1045	2.128e-19	93.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1XDAG@135614|Xanthomonadales	135614|Xanthomonadales	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRD1_k127_2996723_0	469383.Cwoe_5590	8.797e-153	520.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I3CX@201174|Actinobacteria	2|Bacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE,Trans_reg_C
SRD1_k127_2996723_12	381666.H16_A3199	7.024e-27	121.0	COG0834@1|root,COG0834@2|Bacteria,1N2RR@1224|Proteobacteria,2VMGM@28216|Betaproteobacteria,1K282@119060|Burkholderiaceae	28216|Betaproteobacteria	ET	SMART extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRD1_k127_2996723_2	1123024.AUII01000022_gene129	4.442e-149	506.0	COG2197@1|root,COG2197@2|Bacteria,2I321@201174|Actinobacteria,4EF7G@85010|Pseudonocardiales	201174|Actinobacteria	KT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRD1_k127_2996723_3	713587.THITH_07785	3.041e-131	438.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,1RRDD@1236|Gammaproteobacteria,1WYW4@135613|Chromatiales	135613|Chromatiales	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRD1_k127_2996723_7	706587.Desti_1998	1.401e-58	211.0	COG0410@1|root,COG0410@2|Bacteria,1MVYI@1224|Proteobacteria,43AR1@68525|delta/epsilon subdivisions,2X64Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRD1_k127_2996723_4	391589.RGAI101_4201	3.508e-81	302.0	COG0411@1|root,COG0559@1|root,COG4177@1|root,COG0411@2|Bacteria,COG0559@2|Bacteria,COG4177@2|Bacteria,1MY1E@1224|Proteobacteria,2TTC6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD1_k127_2996723_8	314265.R2601_10719	2.453e-51	193.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TSCF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD1_k127_2996723_9	991905.SL003B_3805	1.474e-39	164.0	COG0683@1|root,COG0683@2|Bacteria,1MVZR@1224|Proteobacteria,2TRRP@28211|Alphaproteobacteria,4BRXD@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	MA20_14925	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRD1_k127_2996723_6	196490.AUEZ01000005_gene3587	9.44e-68	237.0	COG0596@1|root,COG0596@2|Bacteria,1MUSF@1224|Proteobacteria,2TSK5@28211|Alphaproteobacteria,3JWU3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRD1_k127_2998093_5	1267534.KB906756_gene645	1.276e-29	138.0	COG1470@1|root,COG3391@1|root,COG4934@1|root,COG1470@2|Bacteria,COG3391@2|Bacteria,COG4934@2|Bacteria,3Y62V@57723|Acidobacteria,2JKVU@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM Peptidase S53, propeptide	-	-	-	-	-	-	-	-	-	-	-	-	Pro-kuma_activ
SRD1_k127_2998093_7	1051632.TPY_1415	1.554e-13	85.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	ko:K08677	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_S8,Pro-kuma_activ
SRD1_k127_2998093_3	469371.Tbis_1500	8.725e-102	351.0	COG0477@1|root,COG2814@2|Bacteria,2I2DZ@201174|Actinobacteria,4DYAW@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRD1_k127_2998093_8	35754.JNYJ01000054_gene9727	1.64e-08	66.0	2DQVM@1|root,338Y0@2|Bacteria,2I9JA@201174|Actinobacteria,4DEM0@85008|Micromonosporales	201174|Actinobacteria	S	LppX_LprAFG lipoprotein	lprG	GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008289,GO:0009405,GO:0009605,GO:0009607,GO:0009966,GO:0010469,GO:0010646,GO:0016020,GO:0020012,GO:0023051,GO:0030312,GO:0030545,GO:0030682,GO:0031982,GO:0035091,GO:0042783,GO:0042785,GO:0043167,GO:0043168,GO:0043207,GO:0043226,GO:0043227,GO:0043230,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044421,GO:0044464,GO:0048018,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051812,GO:0051832,GO:0051834,GO:0051861,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0065009,GO:0071944,GO:0075136,GO:0097367,GO:0097691,GO:0098772,GO:1903561	-	ko:K14954,ko:K14955	ko05152,map05152	-	-	-	ko00000,ko00001	-	-	-	LppX_LprAFG
SRD1_k127_2998093_2	926569.ANT_28670	5e-119	397.0	COG1252@1|root,COG1252@2|Bacteria,2G5SS@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRD1_k127_2998093_1	204669.Acid345_2863	1.377e-129	425.0	COG3285@1|root,COG3285@2|Bacteria,3Y637@57723|Acidobacteria,2JM9H@204432|Acidobacteriia	204432|Acidobacteriia	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRD1_k127_2998093_0	1120950.KB892707_gene4619	7.235e-159	519.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria	201174|Actinobacteria	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRD1_k127_2998093_4	1120950.KB892783_gene345	4.098e-69	258.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria,4DP7U@85009|Propionibacteriales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
SRD1_k127_2998093_6	1206739.BAGJ01000272_gene5377	2.702e-18	100.0	COG1309@1|root,COG1309@2|Bacteria,2HAGC@201174|Actinobacteria,4G0E6@85025|Nocardiaceae	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	ko:K18476	-	M00668	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C,TetR_N
SRD1_k127_2998940_1	561175.KB894094_gene1713	4.479e-133	436.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4EG4C@85012|Streptosporangiales	201174|Actinobacteria	K	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
SRD1_k127_2998940_7	1196322.A370_04879	2.781e-32	136.0	COG1266@1|root,COG1266@2|Bacteria,1VXTB@1239|Firmicutes,24HAI@186801|Clostridia	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRD1_k127_2998940_9	1206733.BAGC01000044_gene850	4.361e-25	110.0	COG1308@1|root,COG1308@2|Bacteria,2GVBU@201174|Actinobacteria	201174|Actinobacteria	K	Domain of unknown function (DUF4342)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
SRD1_k127_2998940_8	1206733.BAGC01000044_gene848	7.429e-29	127.0	2EHMA@1|root,33BD2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRD1_k127_2998940_4	350058.Mvan_3112	3.755e-48	193.0	COG2267@1|root,COG2267@2|Bacteria,2I4FK@201174|Actinobacteria,23FD3@1762|Mycobacteriaceae	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRD1_k127_2998940_12	861299.J421_1637	1.994e-07	61.0	2C1P2@1|root,32Y1F@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRD1_k127_2998940_0	653045.Strvi_4056	1.94e-145	491.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	AAA_22,GerE,NB-ARC,TPR_12
SRD1_k127_2998940_10	987059.RBXJA2T_06020	3.842e-10	66.0	2EIKM@1|root,33CBX@2|Bacteria,1NHWG@1224|Proteobacteria,2W4IF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_2998940_3	196162.Noca_3341	2.639e-69	238.0	COG1832@1|root,COG1832@2|Bacteria,2IJYY@201174|Actinobacteria	201174|Actinobacteria	S	PFAM CoA-binding domain protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRD1_k127_2998940_13	543632.JOJL01000026_gene2584	2.954e-07	62.0	COG3087@1|root,COG3087@2|Bacteria	2|Bacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	dacA1	-	3.4.16.4	ko:K01286,ko:K06186,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011,ko02000	1.B.33.1	-	-	CD225,NYN,Peptidase_S11,SPOR
SRD1_k127_2998940_6	1146883.BLASA_1057	1.015e-34	154.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4EVZ3@85013|Frankiales	201174|Actinobacteria	T	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRD1_k127_2998940_5	1463921.JODF01000044_gene6447	1.054e-45	173.0	COG2197@1|root,COG2197@2|Bacteria,2GJKM@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	yhcZ	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD1_k127_2998940_2	1121472.AQWN01000006_gene1831	5.895e-112	386.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,26166@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,NAD_binding_8,Pyr_redox_2
SRD1_k127_3003455_2	446470.Snas_1276	1.334e-23	100.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4EXWA@85014|Glycomycetales	201174|Actinobacteria	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRD1_k127_3003455_0	1128421.JAGA01000002_gene140	8.17e-152	493.0	COG0649@1|root,COG0649@2|Bacteria,2NNWG@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa,NiFeSe_Hases
SRD1_k127_3003455_1	936136.ARRT01000006_gene5767	5.209e-37	146.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2UPFY@28211|Alphaproteobacteria,4B9SR@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	oxidoreductase	nuoE2	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRD1_k127_3004590_1	1487923.DP73_09905	5.448e-107	357.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,2607C@186807|Peptococcaceae	186801|Clostridia	C	PFAM CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRD1_k127_3004590_4	1242864.D187_009156	3.466e-51	189.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2WPDF@28221|Deltaproteobacteria,2YVGY@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
SRD1_k127_3004590_0	1382358.JHVN01000006_gene72	1.616e-128	432.0	COG0644@1|root,COG0644@2|Bacteria,1TRRU@1239|Firmicutes,4HBFQ@91061|Bacilli,21VHM@150247|Anoxybacillus	91061|Bacilli	C	Thi4 family	-	-	-	ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,Trp_halogenase
SRD1_k127_3004590_5	479435.Kfla_4088	2.997e-41	171.0	COG1073@1|root,COG1073@2|Bacteria,2I44C@201174|Actinobacteria,4DRNF@85009|Propionibacteriales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRD1_k127_3004590_2	479434.Sthe_2181	1.354e-97	337.0	COG2041@1|root,COG2041@2|Bacteria,2G76Y@200795|Chloroflexi,27XUT@189775|Thermomicrobia	189775|Thermomicrobia	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRD1_k127_3004590_3	479434.Sthe_1950	5.739e-60	222.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRD1_k127_302095_1	558173.CDOO_03265	6e-21	104.0	COG0389@1|root,COG0389@2|Bacteria,2GMZ3@201174|Actinobacteria,22KH4@1653|Corynebacteriaceae	201174|Actinobacteria	L	DNA polymerase involved in DNA repair	dinB_2	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
SRD1_k127_302095_2	383372.Rcas_1048	3.843e-19	94.0	COG0617@1|root,COG0617@2|Bacteria,2G8X7@200795|Chloroflexi	200795|Chloroflexi	J	Aminoglycoside-2''-adenylyltransferase	-	-	-	ko:K19545	-	-	-	-	ko00000,ko01504	-	-	-	NTP_transf_5
SRD1_k127_302095_0	1267535.KB906767_gene1831	3.764e-49	191.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria,2JKQG@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRD1_k127_3023821_0	234267.Acid_4688	0.0	1039.0	COG0577@1|root,COG0577@2|Bacteria,3Y73F@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRD1_k127_3030120_3	485913.Krac_12259	2.358e-17	84.0	COG1028@1|root,COG1028@2|Bacteria,2G8G1@200795|Chloroflexi	485913.Krac_12259|-	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3030120_2	518766.Rmar_0192	2.774e-29	125.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1FJAI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRD1_k127_3030120_1	479434.Sthe_0116	7.24e-57	210.0	COG2146@1|root,COG4244@1|root,COG2146@2|Bacteria,COG4244@2|Bacteria	2|Bacteria	E	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231,Rieske
SRD1_k127_3030120_0	469371.Tbis_2102	1.276e-147	476.0	COG0362@1|root,COG0362@2|Bacteria,2GJ2J@201174|Actinobacteria,4DZCG@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRD1_k127_303324_10	414684.RC1_3175	1.207e-05	57.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TRTE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EU	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRD1_k127_303324_9	1449353.JQMQ01000005_gene5023	4.253e-06	54.0	COG1366@1|root,COG1366@2|Bacteria,2GVID@201174|Actinobacteria	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	MEDS,STAS_2
SRD1_k127_303324_3	479433.Caci_7185	1.909e-71	260.0	COG2172@1|root,COG2172@2|Bacteria,2GKU6@201174|Actinobacteria	201174|Actinobacteria	T	anti-sigma regulatory factor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS
SRD1_k127_303324_4	1122611.KB903944_gene1082	2.004e-51	199.0	COG1835@1|root,COG1835@2|Bacteria,2GKUS@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRD1_k127_303324_0	1122138.AQUZ01000011_gene4922	2.179e-98	336.0	COG1835@1|root,COG1835@2|Bacteria,2GKUS@201174|Actinobacteria,4DS4D@85009|Propionibacteriales	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRD1_k127_303324_6	1382306.JNIM01000001_gene1708	3.732e-25	117.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_25
SRD1_k127_303324_1	216594.MMAR_3322	4.26e-97	329.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,233TJ@1762|Mycobacteriaceae	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase	-	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRD1_k127_303324_2	1108045.GORHZ_125_00290	6.979e-74	262.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria,4GBU0@85026|Gordoniaceae	201174|Actinobacteria	C	Dehydrogenase E1 component	acoA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRD1_k127_303324_7	264198.Reut_B4834	8.92e-17	94.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRD1_k127_303324_8	316274.Haur_1430	1.637e-12	68.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia	200795|Chloroflexi	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRD1_k127_3036316_2	1429046.RR21198_1177	2.832e-10	65.0	COG1752@1|root,COG1752@2|Bacteria,2HJ6N@201174|Actinobacteria,4G5HY@85025|Nocardiaceae	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRD1_k127_3036316_1	711393.AYRX01000083_gene4724	6.242e-33	144.0	COG0517@1|root,COG2823@1|root,COG0517@2|Bacteria,COG2823@2|Bacteria,2IEKD@201174|Actinobacteria	201174|Actinobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRD1_k127_3036316_0	469383.Cwoe_5231	4.589e-93	313.0	COG3892@1|root,COG3892@2|Bacteria,2INPC@201174|Actinobacteria,4CRB8@84995|Rubrobacteria	84995|Rubrobacteria	G	Uncharacterized protein conserved in bacteria (DUF2090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2090
SRD1_k127_303917_5	699218.HMPREF0889_0902	6.489e-47	171.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4H2Y7@909932|Negativicutes	909932|Negativicutes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRD1_k127_303917_4	479434.Sthe_1032	2.176e-54	200.0	COG0049@1|root,COG0049@2|Bacteria,2G6GR@200795|Chloroflexi,27Y66@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRD1_k127_303917_3	525909.Afer_0393	3.193e-59	211.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4CN6J@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRD1_k127_303917_2	443255.SCLAV_4722	3.887e-69	240.0	COG2813@1|root,COG2813@2|Bacteria,2IFG7@201174|Actinobacteria	201174|Actinobacteria	J	methyltransferase small	rsmC	-	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
SRD1_k127_303917_1	479433.Caci_8318	9.468e-124	415.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRD1_k127_303917_0	1449353.JQMQ01000005_gene2422	3.476e-133	433.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,2NFTX@228398|Streptacidiphilus	201174|Actinobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRD1_k127_303917_6	330084.JNYZ01000008_gene6617	1.055e-41	154.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4E9CQ@85010|Pseudonocardiales	201174|Actinobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRD1_k127_3044143_5	1122182.KB903838_gene4195	2.146e-12	70.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4D9HS@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
SRD1_k127_3044143_2	1343740.M271_10830	1.195e-71	253.0	COG0697@1|root,COG0697@2|Bacteria,2GP9G@201174|Actinobacteria	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter DMT superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF1918,EamA
SRD1_k127_3044143_3	1205910.B005_1471	4.978e-62	229.0	COG0842@1|root,COG0842@2|Bacteria,2I0XU@201174|Actinobacteria,4EGKP@85012|Streptosporangiales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRD1_k127_3044143_1	68170.KL590533_gene5260	7.74e-95	327.0	COG0842@1|root,COG0842@2|Bacteria,2IART@201174|Actinobacteria,4E1XJ@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
SRD1_k127_3044143_0	1125971.ASJB01000099_gene2288	1.597e-111	381.0	COG1131@1|root,COG1131@2|Bacteria,2IBJD@201174|Actinobacteria,4E1YQ@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRD1_k127_3044143_4	1173027.Mic7113_1033	2.525e-58	215.0	COG0745@1|root,COG2114@1|root,COG4753@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG4753@2|Bacteria,COG5002@2|Bacteria,1G2RJ@1117|Cyanobacteria,1H9PS@1150|Oscillatoriales	1117|Cyanobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HATPase_c,HisKA,PAS_4,Response_reg
SRD1_k127_3045846_2	744872.Spica_1149	7.454e-08	61.0	COG1664@1|root,COG1664@2|Bacteria,2J861@203691|Spirochaetes	203691|Spirochaetes	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRD1_k127_3045846_0	146922.JOFU01000052_gene2304	1.335e-100	338.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria	201174|Actinobacteria	G	Fructose-1,6-bisphosphatase	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRD1_k127_3045846_1	479434.Sthe_0360	2.033e-44	162.0	COG0318@1|root,COG0318@2|Bacteria,2G5SX@200795|Chloroflexi	200795|Chloroflexi	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD1_k127_3049019_6	405948.SACE_7128	3.425e-08	64.0	COG2227@1|root,COG2227@2|Bacteria,2I3CT@201174|Actinobacteria,4E5NU@85010|Pseudonocardiales	201174|Actinobacteria	H	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRD1_k127_3049019_7	644283.Micau_2504	1.602e-05	51.0	296AY@1|root,2ZTKU@2|Bacteria,2GYWU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3049019_2	485913.Krac_2834	8.444e-106	357.0	COG4638@1|root,COG4638@2|Bacteria,2G75N@200795|Chloroflexi	200795|Chloroflexi	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRD1_k127_3049019_5	666510.ASAC_0549	1.649e-12	80.0	COG0517@1|root,arCOG00606@2157|Archaea,2XR4V@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRD1_k127_3049019_0	298655.KI912266_gene1909	7.227e-125	405.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4EUQX@85013|Frankiales	201174|Actinobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
SRD1_k127_3049019_4	29581.BW37_04598	1.388e-13	76.0	2EADY@1|root,334HI@2|Bacteria,1QV05@1224|Proteobacteria	1224|Proteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRD1_k127_3049019_1	670487.Ocepr_0388	4.699e-109	381.0	COG1171@1|root,COG1171@2|Bacteria,1WI3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD1_k127_3049019_3	1048339.KB913029_gene1556	2.307e-77	270.0	COG0596@1|root,COG0596@2|Bacteria,2I3PB@201174|Actinobacteria,4EXHN@85013|Frankiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
SRD1_k127_3055116_0	644966.Tmar_1398	1.965e-164	521.0	COG2225@1|root,COG2225@2|Bacteria,1TPE8@1239|Firmicutes,24Z0I@186801|Clostridia	186801|Clostridia	H	Belongs to the malate synthase family	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRD1_k127_3055116_1	106370.Francci3_2659	2.042e-101	339.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4ET1B@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD1_k127_3055116_2	469383.Cwoe_3748	3.061e-26	116.0	COG1902@1|root,COG1902@2|Bacteria,2IHUT@201174|Actinobacteria	201174|Actinobacteria	C	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRD1_k127_3065424_1	42256.RradSPS_0187	3.01e-53	192.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4CQV5@84995|Rubrobacteria	84995|Rubrobacteria	EU	Peptidase S9, prolyl oligopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRD1_k127_3065424_0	1386089.N865_19060	3.14e-155	502.0	2DCM0@1|root,2ZEJX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3068984_0	106370.Francci3_3984	2.585e-27	114.0	COG3585@1|root,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,4ET46@85013|Frankiales	201174|Actinobacteria	H	DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,MerR,TOBE
SRD1_k127_3068984_1	1120973.AQXL01000125_gene3126	3.004e-13	76.0	COG5267@1|root,COG5267@2|Bacteria,1VGX0@1239|Firmicutes,4HUYI@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
SRD1_k127_3069254_0	1206720.BAFQ01000147_gene3763	1.618e-186	599.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,4FVWD@85025|Nocardiaceae	201174|Actinobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD_5
SRD1_k127_3069254_7	1146883.BLASA_1859	3.062e-31	124.0	2EMVE@1|root,33FHN@2|Bacteria,2I5BN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3069254_4	1122138.AQUZ01000011_gene4922	7.441e-45	181.0	COG1835@1|root,COG1835@2|Bacteria,2GKUS@201174|Actinobacteria,4DS4D@85009|Propionibacteriales	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRD1_k127_3069254_11	234267.Acid_2441	2.867e-06	57.0	COG2020@1|root,COG2020@2|Bacteria,3Y8EC@57723|Acidobacteria	57723|Acidobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRD1_k127_3069254_12	1206744.BAGL01000058_gene2020	0.0003521	45.0	COG0748@1|root,COG0748@2|Bacteria,2IP6Y@201174|Actinobacteria,4G3D8@85025|Nocardiaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRD1_k127_3069254_13	446470.Snas_3455	0.0005136	48.0	28X37@1|root,2ZJ1Q@2|Bacteria,2HD08@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3069254_5	546414.Deide_03670	7.244e-40	158.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_18
SRD1_k127_3069254_8	1323361.JPOC01000073_gene3679	9.889e-16	90.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FUTU@85025|Nocardiaceae	201174|Actinobacteria	K	activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC,TPR_12
SRD1_k127_3069254_3	1123276.KB893264_gene4598	1.656e-73	265.0	COG2133@1|root,COG3386@1|root,COG4386@1|root,COG2133@2|Bacteria,COG3386@2|Bacteria,COG4386@2|Bacteria,4PNUT@976|Bacteroidetes,47YJ9@768503|Cytophagia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
SRD1_k127_3069254_9	1382306.JNIM01000001_gene3294	6.149e-10	70.0	2EEHZ@1|root,338BU@2|Bacteria,2G9GC@200795|Chloroflexi	200795|Chloroflexi	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
SRD1_k127_3069254_10	278963.ATWD01000001_gene3079	9.614e-10	68.0	COG5343@1|root,COG5343@2|Bacteria,3Y541@57723|Acidobacteria,2JJTM@204432|Acidobacteriia	204432|Acidobacteriia	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRD1_k127_3069254_6	1382356.JQMP01000003_gene1500	2.93e-39	153.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,27Z8H@189775|Thermomicrobia	189775|Thermomicrobia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_3069254_2	1121272.KB903249_gene2239	2.433e-109	362.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DB8J@85008|Micromonosporales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRD1_k127_3069254_1	1380393.JHVP01000001_gene2285	1.687e-110	364.0	COG1228@1|root,COG1228@2|Bacteria,2IE2S@201174|Actinobacteria	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRD1_k127_3069819_5	35841.BT1A1_0610	1.447e-25	116.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,4HBPI@91061|Bacilli,1ZB6W@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRD1_k127_3069819_0	1120983.KB894570_gene1409	5.384e-93	317.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U256@28211|Alphaproteobacteria,1JQFA@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
SRD1_k127_3069819_6	1206731.BAGB01000049_gene5003	1.182e-15	82.0	COG1610@1|root,COG1610@2|Bacteria,2GQVP@201174|Actinobacteria,4G44H@85025|Nocardiaceae	201174|Actinobacteria	S	YqeY-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRD1_k127_3069819_3	1123258.AQXZ01000018_gene415	2.335e-26	112.0	COG0662@1|root,COG0662@2|Bacteria,2IRGP@201174|Actinobacteria	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD1_k127_3069819_1	272558.10176195	3.737e-89	303.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,1ZBDJ@1386|Bacillus	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRD1_k127_3069819_4	768710.DesyoDRAFT_2954	1.061e-25	113.0	COG2440@1|root,COG2440@2|Bacteria,1V6DH@1239|Firmicutes,24P1D@186801|Clostridia,262XZ@186807|Peptococcaceae	186801|Clostridia	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	-	ko:K03855	-	-	-	-	ko00000	-	-	-	ETF_QO
SRD1_k127_3069819_2	1444309.JAQG01000017_gene755	3.036e-56	204.0	COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli,26SYE@186822|Paenibacillaceae	91061|Bacilli	E	peptidase M20	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRD1_k127_3072136_2	760568.Desku_0333	2.026e-49	180.0	COG1250@1|root,COG1250@2|Bacteria,1TPA4@1239|Firmicutes,24DBH@186801|Clostridia,263NE@186807|Peptococcaceae	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRD1_k127_3072136_3	1283299.AUKG01000001_gene1898	4.271e-43	168.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4CQ97@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRD1_k127_3072136_0	765420.OSCT_1630	8.818e-210	667.0	COG1884@1|root,COG1884@2|Bacteria,2G5TP@200795|Chloroflexi,376KZ@32061|Chloroflexia	32061|Chloroflexia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRD1_k127_3072136_4	926564.KI911760_gene4939	1.22e-35	154.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD1_k127_3072136_1	316274.Haur_0944	5.439e-183	589.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi,3750V@32061|Chloroflexia	32061|Chloroflexia	I	PFAM carboxyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRD1_k127_3074420_4	1121423.JONT01000001_gene2099	1.904e-100	337.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,2492A@186801|Clostridia,2608E@186807|Peptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRD1_k127_3074420_2	235909.GK2423	9.796e-186	596.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli,1WEFM@129337|Geobacillus	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRD1_k127_3074420_1	1449126.JQKL01000061_gene1910	5.05e-265	832.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,2682S@186813|unclassified Clostridiales	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRD1_k127_3074420_5	485916.Dtox_1176	2.681e-86	309.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRD1_k127_3074420_3	644966.Tmar_0951	4.056e-145	471.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WCS5@538999|Clostridiales incertae sedis	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRD1_k127_3074420_0	760568.Desku_0006	4.536e-281	887.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,2601Z@186807|Peptococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRD1_k127_3074420_7	58123.JOFJ01000007_gene744	2.801e-28	123.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4EGKZ@85012|Streptosporangiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRD1_k127_3074420_6	867903.ThesuDRAFT_01767	1.839e-29	122.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,3WD8H@538999|Clostridiales incertae sedis	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_3076_3	1121439.dsat_1170	1.46e-39	152.0	COG2606@1|root,COG2606@2|Bacteria,1RD82@1224|Proteobacteria,42TQP@68525|delta/epsilon subdivisions,2WRPZ@28221|Deltaproteobacteria,2MC5U@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRD1_k127_3076_1	335543.Sfum_1360	2.18e-75	270.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria,2MQ6W@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRD1_k127_3076_2	383372.Rcas_4390	3.543e-56	209.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi,374VS@32061|Chloroflexia	32061|Chloroflexia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
SRD1_k127_3076_5	383372.Rcas_4391	1.509e-33	136.0	COG0576@1|root,COG0576@2|Bacteria,2G77I@200795|Chloroflexi,375MV@32061|Chloroflexia	32061|Chloroflexia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRD1_k127_3076_0	555079.Toce_0910	1.364e-119	394.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,42ESV@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRD1_k127_3076_6	1174684.EBMC1_11405	2.947e-18	96.0	COG0708@1|root,COG3210@1|root,COG3468@1|root,COG4625@1|root,COG0708@2|Bacteria,COG3210@2|Bacteria,COG3468@2|Bacteria,COG4625@2|Bacteria,1QUXB@1224|Proteobacteria,2TX5F@28211|Alphaproteobacteria,2KEGN@204457|Sphingomonadales	204457|Sphingomonadales	MU	Putative Ig domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,He_PIG,TIG
SRD1_k127_3076_4	1229172.JQFA01000005_gene267	4.618e-39	163.0	COG0642@1|root,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRD1_k127_3093463_1	1205680.CAKO01000029_gene5141	2.011e-20	103.0	COG2211@1|root,COG2211@2|Bacteria,1R8C2@1224|Proteobacteria,2UNMW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD1_k127_3093463_0	871968.DESME_15235	0.0	1213.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,260NC@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRD1_k127_3126119_0	525904.Tter_2236	1.395e-78	271.0	COG1975@1|root,COG1975@2|Bacteria,2NPTS@2323|unclassified Bacteria	2|Bacteria	O	XdhC and CoxI family	pucA	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRD1_k127_3126119_1	525904.Tter_1921	3.695e-42	161.0	COG5516@1|root,COG5516@2|Bacteria	2|Bacteria	S	CGNR zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRD1_k127_3129199_0	1210884.HG799465_gene12056	1.78e-96	324.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3129199_2	926550.CLDAP_22650	1.402e-63	228.0	COG4947@1|root,COG4947@2|Bacteria	2|Bacteria	P	esterase	XK27_05675	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRD1_k127_3129199_1	1172186.KB911466_gene1411	1.369e-67	235.0	COG0701@1|root,COG0701@2|Bacteria,2GJWR@201174|Actinobacteria,2336Z@1762|Mycobacteriaceae	201174|Actinobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
SRD1_k127_3132346_0	316274.Haur_0133	1.591e-161	515.0	COG0473@1|root,COG0473@2|Bacteria	2|Bacteria	CE	3-isopropylmalate dehydrogenase activity	icd	-	1.1.1.41,1.1.1.85	ko:K00030,ko:K00052	ko00020,ko00290,ko00660,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00290,map00660,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00432,M00535	R00709,R00994,R04426,R10052	RC00084,RC00114,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRD1_k127_3132346_1	1111135.HMPREF1248_1113	2.302e-13	82.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4CWGB@84998|Coriobacteriia	84998|Coriobacteriia	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRD1_k127_3132346_3	1401067.HMPREF0872_08700	5.178e-08	57.0	COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes,4H682@909932|Negativicutes	909932|Negativicutes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRD1_k127_3132346_2	373903.Hore_01040	5.776e-10	61.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,3WAP2@53433|Halanaerobiales	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRD1_k127_3155915_5	479434.Sthe_0360	6.664e-64	228.0	COG0318@1|root,COG0318@2|Bacteria,2G5SX@200795|Chloroflexi	200795|Chloroflexi	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD1_k127_3155915_6	926560.KE387027_gene861	6.903e-59	220.0	COG0477@1|root,COG2814@2|Bacteria,1WJCM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRD1_k127_3155915_12	644966.Tmar_2009	5.419e-05	53.0	COG3339@1|root,COG3339@2|Bacteria,1VQH0@1239|Firmicutes,24X4Z@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRD1_k127_3155915_9	871968.DESME_15760	5.76e-30	125.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,26287@186807|Peptococcaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRD1_k127_3155915_1	635013.TherJR_2972	1.573e-132	436.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,260E3@186807|Peptococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRD1_k127_3155915_0	644966.Tmar_2349	3.001e-137	453.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3WCYT@538999|Clostridiales incertae sedis	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRD1_k127_3155915_4	469383.Cwoe_0139	2.661e-67	248.0	COG3214@1|root,COG3214@2|Bacteria,2HPYW@201174|Actinobacteria,4CRE6@84995|Rubrobacteria	84995|Rubrobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRD1_k127_3155915_11	760192.Halhy_0960	2.553e-07	63.0	COG4447@1|root,COG4447@2|Bacteria,4P16I@976|Bacteroidetes,1IWTV@117747|Sphingobacteriia	2|Bacteria	G	SPTR Glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRD1_k127_3155915_8	314271.RB2654_10663	3.21e-33	141.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2U9H4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRD1_k127_3155915_7	525904.Tter_1678	4.898e-41	168.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRD1_k127_3155915_2	316274.Haur_0210	1.597e-109	368.0	COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi,375R7@32061|Chloroflexia	32061|Chloroflexia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRD1_k127_3155915_10	479434.Sthe_0700	2.65e-21	97.0	2E63U@1|root,330SV@2|Bacteria,2G9KB@200795|Chloroflexi,27YPM@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3155915_3	1304865.JAGF01000001_gene95	1.938e-71	261.0	COG2206@1|root,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria	201174|Actinobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
SRD1_k127_3156013_2	1123234.AUKI01000011_gene1114	2.226e-15	76.0	COG1233@1|root,COG1233@2|Bacteria,4NF31@976|Bacteroidetes,1HYWT@117743|Flavobacteriia	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	pys	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRD1_k127_3156013_0	105422.BBPM01000097_gene5229	4.617e-191	604.0	COG3214@1|root,COG3214@2|Bacteria,2GJM7@201174|Actinobacteria,2NH21@228398|Streptacidiphilus	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRD1_k127_3156013_3	68570.DC74_7073	3.993e-09	67.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRD1_k127_3156013_4	1133850.SHJG_2373	1.387e-05	56.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRD1_k127_3156013_1	1380347.JNII01000006_gene1844	8.59e-21	104.0	COG2372@1|root,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria,4ESVK@85013|Frankiales	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRD1_k127_31611_1	13035.Dacsa_0912	5.976e-13	77.0	COG1544@1|root,COG1544@2|Bacteria,1G152@1117|Cyanobacteria	1117|Cyanobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRD1_k127_31611_0	401526.TcarDRAFT_1915	3.735e-144	468.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,4H28E@909932|Negativicutes	909932|Negativicutes	U	PFAM Type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRD1_k127_317324_0	644966.Tmar_0761	1.684e-101	336.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,25E67@186801|Clostridia,3WDRU@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB
SRD1_k127_317324_1	436229.JOEH01000002_gene3387	7.164e-53	196.0	COG2120@1|root,COG2120@2|Bacteria,2GIUS@201174|Actinobacteria,2NF6K@228398|Streptacidiphilus	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRD1_k127_317324_3	1089551.KE386572_gene963	9.908e-19	90.0	COG2905@1|root,COG2905@2|Bacteria,1PFAE@1224|Proteobacteria,2VACV@28211|Alphaproteobacteria,4BSKG@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRD1_k127_317324_2	1121472.AQWN01000005_gene2358	1.657e-21	100.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24PNN@186801|Clostridia,2673P@186807|Peptococcaceae	186801|Clostridia	S	HAD-superfamily hydrolase, subfamily IIB	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRD1_k127_31762_5	1128398.Curi_c10730	4.068e-44	168.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,26AQ4@186813|unclassified Clostridiales	186801|Clostridia	E	Beta-eliminating lyase	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRD1_k127_31762_6	479431.Namu_4896	5.814e-42	174.0	COG2203@1|root,COG2508@1|root,COG2203@2|Bacteria,COG2508@2|Bacteria,2GM1G@201174|Actinobacteria,4ET7V@85013|Frankiales	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HTH_30
SRD1_k127_31762_14	1499683.CCFF01000014_gene4129	9.106e-05	54.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,36F8Y@31979|Clostridiaceae	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRD1_k127_31762_0	1303518.CCALI_01633	3.181e-221	695.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRD1_k127_31762_1	1380390.JIAT01000011_gene2763	1.301e-156	508.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CP60@84995|Rubrobacteria	84995|Rubrobacteria	P	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRD1_k127_31762_8	1158345.JNLL01000001_gene1083	1.474e-28	119.0	COG0347@1|root,COG0347@2|Bacteria,2G43N@200783|Aquificae	200783|Aquificae	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRD1_k127_31762_7	926560.KE387023_gene2058	2.849e-33	138.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRD1_k127_31762_9	1267535.KB906767_gene2625	1.977e-28	120.0	COG3118@1|root,COG3118@2|Bacteria,3Y53D@57723|Acidobacteria,2JJHK@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRD1_k127_31762_4	1032480.MLP_17940	1.312e-54	212.0	COG1215@1|root,COG1215@2|Bacteria,2IK1V@201174|Actinobacteria	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_31762_10	479434.Sthe_3097	8.309e-22	109.0	2BQKI@1|root,32JGJ@2|Bacteria,2G9SN@200795|Chloroflexi,27YIJ@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRD1_k127_31762_13	1340434.AXVA01000013_gene320	1.656e-07	63.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,1TRS8@1239|Firmicutes,4H9XH@91061|Bacilli,1ZCZW@1386|Bacillus	91061|Bacilli	C	Menaquinol-cytochrome c reductase cytochrome b c subunit	qcrC	-	-	ko:K03888	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_C,Cytochrome_CBB3
SRD1_k127_31762_3	1499968.TCA2_2517	3.493e-63	224.0	COG1290@1|root,COG1290@2|Bacteria,1TP6M@1239|Firmicutes,4H9XV@91061|Bacilli,26S8U@186822|Paenibacillaceae	91061|Bacilli	C	Electron transport protein	qcrB	-	-	ko:K03887	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_B
SRD1_k127_31762_11	1148.1653923	8.951e-14	78.0	COG0723@1|root,COG0723@2|Bacteria,1G03Q@1117|Cyanobacteria,1H5CK@1142|Synechocystis	1117|Cyanobacteria	C	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions	petC	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	CytB6-F_Fe-S,Rieske
SRD1_k127_31762_2	552811.Dehly_1025	3.273e-91	311.0	COG0180@1|root,COG0180@2|Bacteria,2G6CG@200795|Chloroflexi,34CX6@301297|Dehalococcoidia	301297|Dehalococcoidia	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRD1_k127_31762_12	634498.mru_1524	2.331e-09	66.0	COG2244@1|root,arCOG02209@2157|Archaea,2XSUR@28890|Euryarchaeota,23PBE@183925|Methanobacteria	183925|Methanobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SRD1_k127_3192230_1	272844.PAB0892	1.254e-54	203.0	COG0066@1|root,arCOG02230@2157|Archaea,2XTXJ@28890|Euryarchaeota,243TQ@183968|Thermococci	183968|Thermococci	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD1	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRD1_k127_3192230_0	67373.JOBF01000027_gene1528	5.837e-125	415.0	COG0119@1|root,COG0119@2|Bacteria	2|Bacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA2	-	2.3.1.182,2.3.3.13,2.3.3.14	ko:K01649,ko:K02594,ko:K09011	ko00290,ko00620,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00271,R01213,R07399	RC00004,RC00067,RC00470,RC01205,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRD1_k127_3192230_2	324602.Caur_1693	3.067e-20	97.0	COG1071@1|root,COG1071@2|Bacteria,2G6HY@200795|Chloroflexi,3754C@32061|Chloroflexia	32061|Chloroflexia	C	PFAM dehydrogenase, E1 component	-	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRD1_k127_3199939_4	357808.RoseRS_2549	1.568e-59	216.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi,376TA@32061|Chloroflexia	32061|Chloroflexia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRD1_k127_3199939_2	1051632.TPY_0663	4.548e-103	356.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,248PD@186801|Clostridia	186801|Clostridia	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
SRD1_k127_3199939_1	479434.Sthe_2949	2.977e-169	557.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,2G665@200795|Chloroflexi,27XZR@189775|Thermomicrobia	189775|Thermomicrobia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,LUD_dom
SRD1_k127_3199939_3	1051632.TPY_1651	7.553e-95	329.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,248KF@186801|Clostridia,3WCGS@538999|Clostridiales incertae sedis	186801|Clostridia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRD1_k127_3199939_0	882083.SacmaDRAFT_2290	5.457e-207	661.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4DXY8@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRD1_k127_3199939_6	1123242.JH636436_gene6	7.107e-18	88.0	COG4911@1|root,COG4911@2|Bacteria,2J02T@203682|Planctomycetes	203682|Planctomycetes	S	conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRD1_k127_3199939_5	479432.Sros_8501	6.395e-48	177.0	COG3467@1|root,COG3467@2|Bacteria,2IQIK@201174|Actinobacteria,4EK1T@85012|Streptosporangiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRD1_k127_3225536_0	760568.Desku_3060	1.724e-196	622.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,2600F@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRD1_k127_3225536_2	479434.Sthe_1032	1.192e-56	202.0	COG0049@1|root,COG0049@2|Bacteria,2G6GR@200795|Chloroflexi,27Y66@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRD1_k127_3225536_1	1184607.AUCHE_08_03380	2.298e-59	209.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4F6YA@85018|Dermatophilaceae	201174|Actinobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRD1_k127_3236039_0	42256.RradSPS_1755	4.599e-81	290.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4CU1Q@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRD1_k127_3236039_3	1382306.JNIM01000001_gene3962	1.625e-24	119.0	COG0652@1|root,COG0652@2|Bacteria,2G6RE@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRD1_k127_3236039_4	1268072.PSAB_12300	1.064e-10	64.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRD1_k127_3236039_1	1089553.Tph_c15420	6.005e-33	137.0	COG0805@1|root,COG0805@2|Bacteria,1U7N7@1239|Firmicutes,24KCD@186801|Clostridia,42GQG@68295|Thermoanaerobacterales	186801|Clostridia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRD1_k127_3236039_2	1123504.JQKD01000015_gene972	2.927e-29	119.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2VIGI@28216|Betaproteobacteria,4A9XQ@80864|Comamonadaceae	28216|Betaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRD1_k127_3240951_2	489825.LYNGBM3L_24950	2.613e-104	348.0	COG0451@1|root,COG0451@2|Bacteria,1G0GJ@1117|Cyanobacteria,1H9Q3@1150|Oscillatoriales	1117|Cyanobacteria	M	NAD dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRD1_k127_3240951_0	264732.Moth_0581	4.102e-261	818.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,42F8U@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRD1_k127_3240951_5	1122921.KB898194_gene726	2.145e-25	120.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,26RFE@186822|Paenibacillaceae	91061|Bacilli	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRD1_k127_3240951_6	1461693.ATO10_06781	1.666e-13	79.0	COG3795@1|root,COG3795@2|Bacteria,1RJJG@1224|Proteobacteria,2UCR2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRD1_k127_3240951_4	479434.Sthe_2063	1.252e-38	161.0	COG1573@1|root,COG1573@2|Bacteria,2G8Q5@200795|Chloroflexi	200795|Chloroflexi	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRD1_k127_3240951_1	255470.cbdbA1382	1.363e-104	349.0	COG1488@1|root,COG1488@2|Bacteria,2G73F@200795|Chloroflexi,34CMV@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRD1_k127_3240951_3	479434.Sthe_0642	5.591e-68	238.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi,27XJW@189775|Thermomicrobia	189775|Thermomicrobia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRD1_k127_3267510_2	667014.Thein_1281	1.178e-30	123.0	COG1350@1|root,COG1350@2|Bacteria,2GHCP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD1_k127_3267510_0	208439.AJAP_03220	0.0	1062.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4DXEE@85010|Pseudonocardiales	201174|Actinobacteria	CH	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
SRD1_k127_3267510_1	67352.JODS01000009_gene7469	4.334e-211	668.0	COG0365@1|root,COG0365@2|Bacteria,2GJVK@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	-	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	4HBT,AMP-binding,AMP-binding_C
SRD1_k127_3267510_3	436229.JOEH01000055_gene5664	9.478e-28	117.0	COG0251@1|root,COG0251@2|Bacteria,2IHXH@201174|Actinobacteria,2NIM1@228398|Streptacidiphilus	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRD1_k127_3267510_4	1089544.KB912942_gene3984	2.195e-14	77.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria,4E2EI@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA5	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRD1_k127_3273455_0	390989.JOEG01000013_gene2489	1.182e-99	339.0	COG0477@1|root,COG2814@2|Bacteria,2I2G0@201174|Actinobacteria,4DIKC@85008|Micromonosporales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRD1_k127_3273455_1	1123321.KB905813_gene865	9.631e-57	202.0	COG0604@1|root,COG0604@2|Bacteria,2GK7Y@201174|Actinobacteria	201174|Actinobacteria	C	NADPH quinone	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD1_k127_3283285_4	771875.Ferpe_0011	1.165e-07	64.0	COG4254@1|root,COG4254@2|Bacteria,2GD0Z@200918|Thermotogae	200918|Thermotogae	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRD1_k127_3283285_2	771875.Ferpe_0011	9.051e-08	64.0	COG4254@1|root,COG4254@2|Bacteria,2GD0Z@200918|Thermotogae	200918|Thermotogae	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRD1_k127_3283285_3	1242864.D187_002073	1.124e-07	62.0	COG3409@1|root,COG3409@2|Bacteria,1Q95M@1224|Proteobacteria,43760@68525|delta/epsilon subdivisions,2X24E@28221|Deltaproteobacteria,2Z001@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3283285_0	42256.RradSPS_2265	8.815e-166	542.0	COG1620@1|root,COG1620@2|Bacteria,2GIUF@201174|Actinobacteria	201174|Actinobacteria	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
SRD1_k127_3283285_1	1306174.JODP01000032_gene4027	5.853e-82	292.0	COG4907@1|root,COG4907@2|Bacteria,2GNW7@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
SRD1_k127_3283534_1	471852.Tcur_3268	8.363e-68	248.0	COG1228@1|root,COG1228@2|Bacteria,2IBKT@201174|Actinobacteria,4EG36@85012|Streptosporangiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRD1_k127_3283534_0	356851.JOAN01000003_gene1381	2.328e-116	389.0	COG0402@1|root,COG0402@2|Bacteria,2GZ2Q@201174|Actinobacteria,4DAQ9@85008|Micromonosporales	201174|Actinobacteria	F	deiminase	hutF	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRD1_k127_3283534_2	1121924.ATWH01000001_gene4341	2.133e-59	206.0	COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria,4FK8Q@85023|Microbacteriaceae	201174|Actinobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRD1_k127_3298771_1	401526.TcarDRAFT_0399	1.463e-120	398.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H34D@909932|Negativicutes	909932|Negativicutes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRD1_k127_3298771_3	1048339.KB913029_gene5054	5.092e-78	284.0	COG3483@1|root,COG3483@2|Bacteria,2GNB1@201174|Actinobacteria,4ESUG@85013|Frankiales	201174|Actinobacteria	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
SRD1_k127_3298771_2	1449347.JQLN01000004_gene6659	2.314e-113	383.0	COG1680@1|root,COG1680@2|Bacteria,2H2SY@201174|Actinobacteria,2M0X5@2063|Kitasatospora	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRD1_k127_3298771_0	469383.Cwoe_1486	9.382e-150	488.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRD1_k127_3298771_4	298653.Franean1_3344	3.651e-30	124.0	COG1846@1|root,COG1846@2|Bacteria,2INK0@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRD1_k127_3298771_5	1303518.CCALI_00338	2.662e-19	98.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Acetyltransf_10,TsaE
SRD1_k127_3298843_9	337191.KTR9_0738	7.932e-15	82.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4GCXC@85026|Gordoniaceae	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_3298843_10	648885.KB316282_gene1879	9.84e-15	84.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2TV3A@28211|Alphaproteobacteria,1JT9M@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_3298843_3	688269.Theth_1211	5.669e-73	263.0	COG1473@1|root,COG1473@2|Bacteria,2GCJT@200918|Thermotogae	200918|Thermotogae	S	peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRD1_k127_3298843_1	1283299.AUKG01000004_gene1069	1.451e-119	412.0	COG0465@1|root,COG0465@2|Bacteria,2I9X7@201174|Actinobacteria,4CRZJ@84995|Rubrobacteria	84995|Rubrobacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
SRD1_k127_3298843_7	1122247.C731_2751	1.573e-31	139.0	COG0741@1|root,COG2027@1|root,COG0741@2|Bacteria,COG2027@2|Bacteria,2IBCH@201174|Actinobacteria,2359I@1762|Mycobacteriaceae	201174|Actinobacteria	M	transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1460,NLPC_P60,SLT,SLT_2
SRD1_k127_3298843_5	443218.AS9A_2146	5.926e-60	216.0	2CAJE@1|root,33XCP@2|Bacteria,2IMDF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3298843_8	1463856.JOHY01000002_gene1325	6.908e-21	101.0	COG0789@1|root,COG0789@2|Bacteria,2I8PU@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRD1_k127_3298843_2	469383.Cwoe_3578	1.03e-75	274.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4CQEB@84995|Rubrobacteria	84995|Rubrobacteria	HQ	chorismate binding enzyme	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRD1_k127_3298843_6	485913.Krac_10280	1.533e-53	205.0	COG0596@1|root,COG0596@2|Bacteria,2G6VQ@200795|Chloroflexi	2|Bacteria	S	PFAM alpha beta hydrolase fold	MA20_20400	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_6
SRD1_k127_3298843_0	479434.Sthe_3024	2.703e-125	421.0	COG1165@1|root,COG1165@2|Bacteria,2G6JR@200795|Chloroflexi,27XZC@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
SRD1_k127_3298843_4	479434.Sthe_3023	1.091e-60	219.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi,27Y8T@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
SRD1_k127_3320303_1	996637.SGM_0145	2.635e-33	128.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRD1_k127_3320303_2	1530186.JQEY01000008_gene3022	1.852e-25	115.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_3320303_0	1500897.JQNA01000002_gene4645	7.772e-129	426.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,HAMP,PAS,PAS_4,PAS_8,PAS_9,dCache_3
SRD1_k127_3325625_2	485915.Dret_1162	3.166e-11	76.0	COG4963@1|root,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,42QEH@68525|delta/epsilon subdivisions,2WKVC@28221|Deltaproteobacteria,2MAS2@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CBP_BcsQ,ParA,Response_reg
SRD1_k127_3325625_1	1209984.BN978_03638	3.884e-17	94.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,236D8@1762|Mycobacteriaceae	201174|Actinobacteria	T	helix_turn_helix, cAMP Regulatory protein	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRD1_k127_3325625_4	644966.Tmar_1538	6.764e-08	65.0	2BY2H@1|root,32R2G@2|Bacteria,1VUIG@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3325625_3	1385518.N798_07485	5.445e-09	68.0	COG4733@1|root,COG4932@1|root,COG4733@2|Bacteria,COG4932@2|Bacteria,2I7XV@201174|Actinobacteria,4FK2V@85021|Intrasporangiaceae	201174|Actinobacteria	M	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
SRD1_k127_3325625_0	33876.JNXY01000021_gene4774	1.05e-31	132.0	COG2852@1|root,COG2852@2|Bacteria,2GN40@201174|Actinobacteria,4DDX1@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRD1_k127_335730_0	1122611.KB903952_gene5821	2.802e-224	703.0	COG2072@1|root,COG2072@2|Bacteria,2GKYU@201174|Actinobacteria,4EMHG@85012|Streptosporangiales	201174|Actinobacteria	P	Flavin-binding monooxygenase-like	pamO	GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0044237,GO:0044249,GO:0046483,GO:0055114,GO:0071704,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901576	1.14.13.170,1.14.13.171,1.14.13.22	ko:K03379,ko:K18091	ko00930,ko01120,ko01130,ko01220,map00930,map01120,map01130,map01220	M00819	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko00002,ko01000	-	-	-	FMO-like,NAD_binding_8,Pyr_redox_2,Pyr_redox_3
SRD1_k127_335730_1	622637.KE124774_gene605	6.122e-11	73.0	COG0454@1|root,COG0456@2|Bacteria,1RK56@1224|Proteobacteria,2UZJE@28211|Alphaproteobacteria,36YRR@31993|Methylocystaceae	28211|Alphaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
SRD1_k127_335730_2	765420.OSCT_0497	1.017e-07	57.0	2DPX2@1|root,333RW@2|Bacteria,2G7A0@200795|Chloroflexi,377B3@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
SRD1_k127_3357841_12	1123024.AUII01000016_gene1246	1.732e-24	105.0	COG2180@1|root,COG2180@2|Bacteria,2IAQV@201174|Actinobacteria,4E3RA@85010|Pseudonocardiales	201174|Actinobacteria	C	Nitrate reductase delta subunit	narJ	-	-	ko:K00373	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Nitrate_red_del
SRD1_k127_3357841_5	1122611.KB903967_gene5176	6.033e-76	261.0	COG2181@1|root,COG2181@2|Bacteria,2GJVI@201174|Actinobacteria,4EMZJ@85012|Streptosporangiales	201174|Actinobacteria	C	Nitrate reductase gamma subunit	narI	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
SRD1_k127_3357841_18	351607.Acel_0515	0.0003489	51.0	2BM3X@1|root,33KY1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3357841_1	42256.RradSPS_0572	1.789e-104	353.0	COG2223@1|root,COG2223@2|Bacteria,2GJ1I@201174|Actinobacteria,4CQM5@84995|Rubrobacteria	84995|Rubrobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
SRD1_k127_3357841_15	1521187.JPIM01000024_gene714	6.42e-08	61.0	2DYEV@1|root,349E2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3357841_17	290340.AAur_0972	1.354e-06	59.0	COG3409@1|root,COG3409@2|Bacteria,2IM37@201174|Actinobacteria,1WBE2@1268|Micrococcaceae	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3357841_0	1232410.KI421428_gene1079	2.29e-127	428.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,43TKN@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRD1_k127_3357841_13	1210045.ALNP01000004_gene3455	8.718e-12	71.0	COG0517@1|root,COG0517@2|Bacteria,2IM3K@201174|Actinobacteria	201174|Actinobacteria	S	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRD1_k127_3357841_7	311424.DhcVS_642	1.243e-65	246.0	COG1028@1|root,COG1028@2|Bacteria,2G6RP@200795|Chloroflexi,34CMA@301297|Dehalococcoidia	301297|Dehalococcoidia	IQ	KR domain	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRD1_k127_3357841_6	469383.Cwoe_3478	1.615e-69	252.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRD1_k127_3357841_2	357808.RoseRS_2761	2.508e-89	310.0	COG1020@1|root,COG1020@2|Bacteria,2G7PI@200795|Chloroflexi	200795|Chloroflexi	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRD1_k127_3357841_4	1033810.HLPCO_002600	2.782e-78	288.0	COG1028@1|root,COG1028@2|Bacteria	1033810.HLPCO_002600|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3357841_9	465541.ATCJ01000005_gene1080	1.441e-34	141.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria	201174|Actinobacteria	C	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRD1_k127_3357841_11	1385518.N798_10605	5.485e-27	115.0	COG3467@1|root,COG3467@2|Bacteria,2IP5U@201174|Actinobacteria,4FGWT@85021|Intrasporangiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
SRD1_k127_3357841_10	909663.KI867150_gene2841	3.44e-34	149.0	COG0662@1|root,COG0662@2|Bacteria,1RJ7D@1224|Proteobacteria,431RV@68525|delta/epsilon subdivisions,2WWFG@28221|Deltaproteobacteria,2MS3I@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD1_k127_3357841_8	1268622.AVS7_03426	3.078e-56	208.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VHCY@28216|Betaproteobacteria,4ABPM@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_9
SRD1_k127_3357841_3	1382356.JQMP01000003_gene1584	4.624e-81	278.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,27XKK@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRD1_k127_3370449_0	1380354.JIAN01000005_gene2141	1.419e-240	755.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria	201174|Actinobacteria	G	Glycoside hydrolase	-	GO:0003674,GO:0003824,GO:0004553,GO:0004555,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0015927,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0042301,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044464,GO:0046352,GO:0071704,GO:0071944,GO:1901575	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRD1_k127_3370449_9	160492.XF_0275	3.827e-48	179.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1X668@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
SRD1_k127_3370449_8	1128421.JAGA01000001_gene2083	5.773e-55	203.0	COG1475@1|root,COG1475@2|Bacteria,2NS1X@2323|unclassified Bacteria	2|Bacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc
SRD1_k127_3370449_2	935948.KE386494_gene413	2.188e-130	424.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,42F3H@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM ABC transporter related	msmX	-	3.6.3.20	ko:K05816,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00198,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.3	-	-	ABC_tran,TOBE,TOBE_2
SRD1_k127_3370449_4	1382306.JNIM01000001_gene1417	5.481e-97	340.0	COG0395@1|root,COG0395@2|Bacteria,2G82A@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRD1_k127_3370449_5	744872.Spica_0828	2.489e-90	308.0	COG1175@1|root,COG1175@2|Bacteria,2J5SW@203691|Spirochaetes	203691|Spirochaetes	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10233	ko02010,map02010	M00201,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRD1_k127_3370449_3	744872.Spica_0827	5.073e-106	359.0	COG1653@1|root,COG1653@2|Bacteria,2J6W1@203691|Spirochaetes	203691|Spirochaetes	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1
SRD1_k127_3370449_7	134676.ACPL_2548	4.893e-80	278.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4DM0W@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRD1_k127_3370449_1	1280390.CBQR020000176_gene4672	2.965e-147	490.0	COG3250@1|root,COG3250@2|Bacteria,1TQAM@1239|Firmicutes,4HB7S@91061|Bacilli,26SR5@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRD1_k127_3370449_6	937777.Deipe_2373	4.649e-87	299.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRD1_k127_3370449_10	471853.Bcav_1145	0.0007551	51.0	COG4813@1|root,COG4813@2|Bacteria,2I8EC@201174|Actinobacteria	201174|Actinobacteria	G	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
SRD1_k127_3378062_1	640081.Dsui_1522	2.136e-41	164.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,2KV51@206389|Rhodocyclales	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
SRD1_k127_3378062_0	118168.MC7420_1326	5.124e-222	702.0	COG1506@1|root,COG1506@2|Bacteria,1G200@1117|Cyanobacteria,1H8T3@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase family	dap2	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRD1_k127_3385923_3	251229.Chro_2918	1.512e-94	318.0	COG0436@1|root,COG0436@2|Bacteria,1GHX7@1117|Cyanobacteria,3VM7E@52604|Pleurocapsales	1117|Cyanobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRD1_k127_3385923_5	1123023.JIAI01000020_gene2104	1.539e-31	124.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	fdhF	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0015942,GO:0015944,GO:0016491,GO:0016651,GO:0016999,GO:0017144,GO:0019752,GO:0030151,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704	1.17.1.10,1.17.1.9,1.17.99.7	ko:K00123,ko:K05299,ko:K22015	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	iECBD_1354.ECBD_3953,iHN637.CLJU_RS04405,iHN637.CLJU_c06990	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRD1_k127_3385923_0	675635.Psed_3298	7.106e-237	743.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4DZUH@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdnG	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
SRD1_k127_3385923_1	675635.Psed_3297	4.923e-189	607.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,2GMMC@201174|Actinobacteria,4E076@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.17.1.9,1.6.5.3	ko:K00122,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
SRD1_k127_3385923_2	28444.JODQ01000008_gene965	2.941e-125	406.0	COG3383@1|root,COG3383@2|Bacteria,2GKBP@201174|Actinobacteria,4EI2K@85012|Streptosporangiales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,NADH-G_4Fe-4S_3
SRD1_k127_3385923_6	1235794.C811_01491	9.049e-15	83.0	COG1595@1|root,COG1595@2|Bacteria,2HG3E@201174|Actinobacteria,4CY5F@84998|Coriobacteriia	84998|Coriobacteriia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_3385923_4	263358.VAB18032_12520	9.488e-52	188.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria,4DBSC@85008|Micromonosporales	201174|Actinobacteria	L	HhH-GPD superfamily base excision DNA repair protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRD1_k127_3399608_5	1111479.AXAR01000009_gene2450	1.704e-41	173.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HVN5@91061|Bacilli	91061|Bacilli	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
SRD1_k127_3399608_4	632245.CLP_2392	2.257e-50	200.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,36EHU@31979|Clostridiaceae	186801|Clostridia	E	Family 5	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRD1_k127_3399608_3	546269.HMPREF0389_00808	8.107e-65	237.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,25R6Q@186804|Peptostreptococcaceae	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
SRD1_k127_3399608_2	867903.ThesuDRAFT_01162	1.958e-77	269.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WD2P@538999|Clostridiales incertae sedis	186801|Clostridia	EP	N-terminal TM domain of oligopeptide transport permease C	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRD1_k127_3399608_1	91464.S7335_4328	6.795e-109	361.0	COG0444@1|root,COG0444@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRD1_k127_3399608_0	1173029.JH980292_gene3994	7.856e-125	413.0	COG4608@1|root,COG4608@2|Bacteria,1G1Q0@1117|Cyanobacteria,1HA59@1150|Oscillatoriales	1117|Cyanobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRD1_k127_3413440_5	69279.BG36_08150	1.406e-05	57.0	COG3307@1|root,COG3307@2|Bacteria,1NI7K@1224|Proteobacteria,2USRW@28211|Alphaproteobacteria,43KZ6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	O-antigen ligase	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
SRD1_k127_3413440_2	1211817.CCAT010000083_gene1670	7.225e-106	357.0	COG0438@1|root,COG0438@2|Bacteria,1UTQH@1239|Firmicutes,24BT3@186801|Clostridia,36F7W@31979|Clostridiaceae	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRD1_k127_3413440_0	697281.Mahau_0358	7.188e-132	429.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,247N7@186801|Clostridia,42HP4@68295|Thermoanaerobacterales	186801|Clostridia	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRD1_k127_3413440_1	926550.CLDAP_36220	1.182e-124	414.0	COG0399@1|root,COG0399@2|Bacteria,2G5QG@200795|Chloroflexi	200795|Chloroflexi	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRD1_k127_3413440_3	867845.KI911784_gene2883	9.689e-92	314.0	COG0673@1|root,COG0673@2|Bacteria,2G6Y0@200795|Chloroflexi,376NR@32061|Chloroflexia	32061|Chloroflexia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRD1_k127_3413440_4	697281.Mahau_0366	7.284e-10	70.0	COG3307@1|root,COG3307@2|Bacteria,1V4W4@1239|Firmicutes,24JD5@186801|Clostridia	186801|Clostridia	M	O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRD1_k127_3427866_7	196162.Noca_1180	1.519e-09	62.0	COG4177@1|root,COG4177@2|Bacteria	2|Bacteria	E	L-phenylalanine transmembrane transporter activity	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD1_k127_3427866_1	1120949.KB903330_gene9148	1.87e-82	282.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4DA7P@85008|Micromonosporales	201174|Actinobacteria	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRD1_k127_3427866_0	1120949.KB903330_gene9147	2.725e-92	309.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4D9QU@85008|Micromonosporales	201174|Actinobacteria	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRD1_k127_3427866_5	1121035.AUCH01000003_gene1360	2.209e-12	80.0	COG3831@1|root,COG3831@2|Bacteria,1QWC3@1224|Proteobacteria,2WFHK@28216|Betaproteobacteria	1224|Proteobacteria	S	Proposed nucleic acid binding domain	JD73_20480	-	-	-	-	-	-	-	-	-	-	-	DUF4132,WGR
SRD1_k127_3427866_3	1179773.BN6_44430	4.589e-44	182.0	2E26J@1|root,32XD0@2|Bacteria,2I8EP@201174|Actinobacteria,4E4KU@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4253)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4253
SRD1_k127_3427866_6	1379698.RBG1_1C00001G1428	1.582e-11	78.0	COG2911@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NS5I@2323|unclassified Bacteria	2|Bacteria	U	FlgD Ig-like domain	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Cytochrome_C554,DUF11,FlgD_ig,PKD,SLH
SRD1_k127_3427866_4	479431.Namu_4659	1.074e-23	118.0	COG3764@1|root,COG3764@2|Bacteria,2IR30@201174|Actinobacteria,4EVPW@85013|Frankiales	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRD1_k127_3427866_2	1298867.AUES01000064_gene46	1.555e-77	271.0	COG1028@1|root,COG1028@2|Bacteria,1MU32@1224|Proteobacteria,2TUYY@28211|Alphaproteobacteria,3JUT8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	KR domain	-	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD1_k127_3432788_2	867845.KI911784_gene2577	3.725e-27	113.0	COG0652@1|root,COG0652@2|Bacteria,2G8IA@200795|Chloroflexi,375NH@32061|Chloroflexia	32061|Chloroflexia	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
SRD1_k127_3432788_1	926550.CLDAP_29430	2.371e-46	183.0	COG0477@1|root,COG2814@2|Bacteria,2G6HS@200795|Chloroflexi	200795|Chloroflexi	EGP	Major facilitator superfamily MFS_1	-	-	-	ko:K08161	-	-	-	-	ko00000,ko02000	2.A.1.2.20	-	-	MFS_1,MFS_1_like
SRD1_k127_3432788_0	469371.Tbis_2228	1.159e-125	423.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4E111@85010|Pseudonocardiales	201174|Actinobacteria	C	xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRD1_k127_3482690_0	469381.Dpep_0113	1.817e-97	335.0	COG0404@1|root,COG0404@2|Bacteria,3TAKY@508458|Synergistetes	508458|Synergistetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRD1_k127_3482690_5	1232453.BAIF02000060_gene1687	7.544e-11	75.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,267PJ@186813|unclassified Clostridiales	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD1_k127_3482690_2	479434.Sthe_1855	5.189e-89	321.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi,27XU8@189775|Thermomicrobia	189775|Thermomicrobia	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
SRD1_k127_3482690_1	316274.Haur_1478	1.897e-90	304.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi,375BD@32061|Chloroflexia	32061|Chloroflexia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRD1_k127_3482690_4	926550.CLDAP_29420	4.036e-27	123.0	COG1266@1|root,COG1266@2|Bacteria,2G9FI@200795|Chloroflexi	200795|Chloroflexi	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRD1_k127_3482690_3	644966.Tmar_2367	8.846e-80	274.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,3WCDY@538999|Clostridiales incertae sedis	186801|Clostridia	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRD1_k127_3482690_6	663278.Ethha_2790	3.618e-10	68.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,3WHV1@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRD1_k127_3482782_1	561175.KB894093_gene3161	9.996e-149	477.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4EHQW@85012|Streptosporangiales	201174|Actinobacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRD1_k127_3482782_0	1122611.KB903940_gene1758	9.631e-151	485.0	COG0296@1|root,COG0296@2|Bacteria,2GMIS@201174|Actinobacteria,4EG9E@85012|Streptosporangiales	201174|Actinobacteria	G	Domain of unknown function (DUF3459)	treZ	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SRD1_k127_3511736_4	861299.J421_0742	7.697e-78	267.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRD1_k127_3511736_0	1382306.JNIM01000001_gene4115	1.524e-200	652.0	COG3845@1|root,COG3845@2|Bacteria,2G625@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRD1_k127_3511736_2	1382306.JNIM01000001_gene4116	9.013e-100	335.0	COG1079@1|root,COG1079@2|Bacteria,2G6BT@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRD1_k127_3511736_5	1382306.JNIM01000001_gene4117	7.695e-68	249.0	COG4603@1|root,COG4603@2|Bacteria,2G6MU@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRD1_k127_3511736_3	485913.Krac_8937	6.109e-97	329.0	COG1744@1|root,COG1744@2|Bacteria,2G6UB@200795|Chloroflexi	200795|Chloroflexi	M	PFAM basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRD1_k127_3511736_1	555079.Toce_0593	8.108e-123	408.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,42FDN@68295|Thermoanaerobacterales	186801|Clostridia	F	PFAM Glycosyl transferase, family 3	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRD1_k127_3511736_6	1391647.AVSV01000007_gene63	1.55e-54	197.0	COG2820@1|root,COG2820@2|Bacteria,1TSEU@1239|Firmicutes,25E2U@186801|Clostridia,36UH1@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRD1_k127_352467_1	525909.Afer_1141	4.58e-41	157.0	COG0747@1|root,COG0747@2|Bacteria,2GZTR@201174|Actinobacteria,4CNEY@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD1_k127_352467_0	1382356.JQMP01000003_gene2464	4.57e-79	286.0	COG4166@1|root,COG4166@2|Bacteria,2GBUU@200795|Chloroflexi,27YZK@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRD1_k127_3537913_2	479434.Sthe_2339	1.506e-36	141.0	COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi,27YHA@189775|Thermomicrobia	189775|Thermomicrobia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRD1_k127_3537913_3	743836.AYNA01000041_gene1066	7.753e-34	138.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,2TRW9@28211|Alphaproteobacteria,36YGA@31993|Methylocystaceae	28211|Alphaproteobacteria	J	FtsJ-like methyltransferase	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRD1_k127_3537913_4	644968.DFW101_0740	1.589e-24	105.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MCF7@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRD1_k127_3537913_1	1122609.AUGT01000029_gene2602	1.178e-52	200.0	COG0204@1|root,COG0204@2|Bacteria,2IAXZ@201174|Actinobacteria,4DPFR@85009|Propionibacteriales	201174|Actinobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRD1_k127_3537913_0	1120950.KB892707_gene4920	3.452e-137	443.0	COG3875@1|root,COG3875@2|Bacteria,2IAM4@201174|Actinobacteria,4DPEW@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRD1_k127_3543658_1	316274.Haur_2351	3.885e-80	277.0	COG0524@1|root,COG0524@2|Bacteria,2G7YR@200795|Chloroflexi,374WD@32061|Chloroflexia	32061|Chloroflexia	G	PFAM PfkB domain protein	-	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRD1_k127_3543658_3	926560.KE387026_gene4175	2.201e-48	186.0	COG0842@1|root,COG0842@2|Bacteria,1WM4H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
SRD1_k127_3543658_0	926560.KE387023_gene3855	2.098e-84	289.0	COG1131@1|root,COG1131@2|Bacteria,1WI6M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_3543658_4	465515.Mlut_07820	1.609e-47	174.0	COG0537@1|root,COG0537@2|Bacteria,2IKWU@201174|Actinobacteria,1W9DB@1268|Micrococcaceae	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRD1_k127_3543658_2	469371.Tbis_2726	3.975e-71	249.0	COG0412@1|root,COG0412@2|Bacteria,2I151@201174|Actinobacteria,4E3BE@85010|Pseudonocardiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRD1_k127_3544026_1	867903.ThesuDRAFT_01477	9.701e-104	341.0	COG2225@1|root,COG2225@2|Bacteria,1TPE8@1239|Firmicutes,24Z0I@186801|Clostridia	186801|Clostridia	H	Belongs to the malate synthase family	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRD1_k127_3544026_3	525904.Tter_0097	6.934e-45	173.0	COG0321@1|root,COG0321@2|Bacteria,2NPE7@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181,2.8.1.8	ko:K03644,ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07767,R07768,R07769	RC00039,RC00992,RC01978,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRD1_k127_3544026_0	266117.Rxyl_2548	2.562e-120	392.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4CPF1@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRD1_k127_3544026_2	525904.Tter_0095	2.958e-75	259.0	COG0508@1|root,COG0508@2|Bacteria,2NNZ8@2323|unclassified Bacteria	2|Bacteria	C	e3 binding domain	bfmBB	-	2.3.1.168,2.3.1.61	ko:K00658,ko:K09699	ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00036	R02570,R02571,R02662,R03174,R04097,R08549,R10998	RC00004,RC02727,RC02833,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRD1_k127_3565874_5	240016.ABIZ01000001_gene4581	8.755e-09	60.0	COG0165@1|root,COG0165@2|Bacteria,46SCX@74201|Verrucomicrobia,2ITKH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRD1_k127_3565874_3	401526.TcarDRAFT_0920	2.705e-85	289.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H2ZZ@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRD1_k127_3565874_2	56110.Oscil6304_1901	1.288e-125	423.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1G34C@1117|Cyanobacteria,1H7EG@1150|Oscillatoriales	1117|Cyanobacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
SRD1_k127_3565874_4	1269813.ATUL01000027_gene2672	9.483e-58	221.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,1RPS3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRD1_k127_3565874_0	264732.Moth_0152	6.249e-165	530.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,42EMJ@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
SRD1_k127_3565874_1	868595.Desca_0020	3.37e-141	459.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,260VV@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRD1_k127_3567208_0	298654.FraEuI1c_6626	1.229e-101	337.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4EU92@85013|Frankiales	201174|Actinobacteria	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRD1_k127_3567208_1	1303518.CCALI_02196	6.672e-45	174.0	COG1633@1|root,COG1814@1|root,COG1633@2|Bacteria,COG1814@2|Bacteria	2|Bacteria	S	cellular manganese ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
SRD1_k127_3592227_4	1386089.N865_18765	1.796e-13	82.0	2E7YB@1|root,332CR@2|Bacteria,2IRTP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
SRD1_k127_3592227_1	207559.Dde_2402	2.405e-59	215.0	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,42MYE@68525|delta/epsilon subdivisions,2WJC7@28221|Deltaproteobacteria,2M8JK@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRD1_k127_3592227_3	1089552.KI911559_gene2260	1.187e-30	138.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2TR5D@28211|Alphaproteobacteria,2JPR6@204441|Rhodospirillales	204441|Rhodospirillales	H	Probable molybdopterin binding domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRD1_k127_3592227_0	219305.MCAG_04305	5.841e-138	443.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4DHNE@85008|Micromonosporales	201174|Actinobacteria	H	Enoyl-CoA hydratase/isomerase	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD1_k127_3592227_2	1200352.A606_10035	5.409e-51	187.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,22JPA@1653|Corynebacteriaceae	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRD1_k127_359275_0	1382359.JIAL01000001_gene1362	2.737e-142	470.0	COG1793@1|root,COG1793@2|Bacteria,3Y3AP@57723|Acidobacteria,2JIGV@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRD1_k127_359275_3	1396141.BATP01000058_gene1959	4.1e-55	213.0	COG1236@1|root,COG1793@1|root,COG1236@2|Bacteria,COG1793@2|Bacteria,46SCR@74201|Verrucomicrobia,2ITPW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	JL	DNA ligase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N,RMMBL
SRD1_k127_359275_8	368408.Tpen_1647	1.27e-29	127.0	COG0063@1|root,arCOG00018@2157|Archaea,2XPXN@28889|Crenarchaeota	28889|Crenarchaeota	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRD1_k127_359275_9	867845.KI911784_gene3044	2.273e-24	111.0	COG2345@1|root,COG2345@2|Bacteria,2G8V0@200795|Chloroflexi,375MI@32061|Chloroflexia	32061|Chloroflexia	K	DeoR-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_DeoR
SRD1_k127_359275_2	390989.JOEG01000001_gene5076	3.365e-66	246.0	COG3371@1|root,COG3371@2|Bacteria,2II34@201174|Actinobacteria,4DDK4@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRD1_k127_359275_4	235985.BBPN01000012_gene6921	8.007e-46	172.0	COG1309@1|root,COG1309@2|Bacteria,2IN8A@201174|Actinobacteria,2NHVT@228398|Streptacidiphilus	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_7,TetR_N
SRD1_k127_359275_11	1166018.FAES_4235	1.559e-15	86.0	COG1413@1|root,COG2905@1|root,COG1413@2|Bacteria,COG2905@2|Bacteria,4PKPI@976|Bacteroidetes,47YF3@768503|Cytophagia	976|Bacteroidetes	CT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
SRD1_k127_359275_7	935839.JAGJ01000005_gene2767	5.003e-37	161.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4F3GB@85017|Promicromonosporaceae	201174|Actinobacteria	D	Phage integrase family	xerD	GO:0008150,GO:0040007	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRD1_k127_359275_1	67275.JOAP01000021_gene1843	3.508e-81	289.0	COG0204@1|root,COG0204@2|Bacteria,2GJKH@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRD1_k127_359275_10	1009370.ALO_08775	2.232e-21	111.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,4H3ET@909932|Negativicutes	909932|Negativicutes	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
SRD1_k127_359275_5	869210.Marky_1576	4.03e-45	171.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD1_k127_359275_6	1280390.CBQR020000140_gene3421	1.559e-39	166.0	COG1361@1|root,COG1361@2|Bacteria,1V4V3@1239|Firmicutes,4HT0D@91061|Bacilli,26QKX@186822|Paenibacillaceae	91061|Bacilli	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
SRD1_k127_359278_10	1089544.KB912942_gene7115	0.0002416	44.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DZRE@85010|Pseudonocardiales	201174|Actinobacteria	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD1_k127_359278_2	1121405.dsmv_0645	2.387e-98	331.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria,2MHR8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Beta-eliminating lyase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRD1_k127_359278_5	309801.trd_0387	1.327e-83	296.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi,27YYI@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRD1_k127_359278_7	867845.KI911784_gene107	1.176e-18	92.0	COG5394@1|root,COG5394@2|Bacteria,2G77C@200795|Chloroflexi,375VS@32061|Chloroflexia	32061|Chloroflexia	K	PFAM PHA accumulation regulator DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc_N
SRD1_k127_359278_0	383372.Rcas_2006	4.627e-161	524.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi,376F1@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRD1_k127_359278_6	710111.FraQA3DRAFT_3976	1.682e-61	226.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4ERGC@85013|Frankiales	201174|Actinobacteria	M	PFAM NAD-dependent epimerase dehydratase	galE2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0501	Epimerase
SRD1_k127_359278_3	1380346.JNIH01000058_gene110	2.722e-96	325.0	COG3173@1|root,COG3173@2|Bacteria,2GMHD@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRD1_k127_359278_1	272560.BPSS1911	4.631e-128	426.0	COG4409@1|root,COG4409@2|Bacteria,1Q513@1224|Proteobacteria,2WB3C@28216|Betaproteobacteria,1K536@119060|Burkholderiaceae	28216|Betaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_2
SRD1_k127_359278_8	981369.JQMJ01000004_gene4644	1.243e-13	77.0	2C6EM@1|root,2ZFYQ@2|Bacteria,2GXX8@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
SRD1_k127_359278_9	28115.HR11_08175	8.395e-11	68.0	COG3743@1|root,COG3743@2|Bacteria,4NQGZ@976|Bacteroidetes,2FT5C@200643|Bacteroidia,230IQ@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4332,HHH_5
SRD1_k127_359278_4	478741.JAFS01000002_gene758	7.565e-84	287.0	COG0516@1|root,COG0516@2|Bacteria,46W51@74201|Verrucomicrobia,37FWR@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	IMP dehydrogenase / GMP reductase domain	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRD1_k127_3594307_1	479434.Sthe_1647	2.701e-34	135.0	COG0277@1|root,COG0277@2|Bacteria,2GA3E@200795|Chloroflexi,27Z04@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRD1_k127_3594307_0	1463825.JNXC01000016_gene5328	2.61e-54	206.0	COG1835@1|root,COG1835@2|Bacteria,2GKUS@201174|Actinobacteria,4E1PA@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRD1_k127_3594307_2	868131.MSWAN_1118	1.251e-30	125.0	COG3324@1|root,arCOG04946@2157|Archaea,2Y0WQ@28890|Euryarchaeota	28890|Euryarchaeota	E	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRD1_k127_3594307_3	926560.KE387027_gene352	3.563e-21	100.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1WMXM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3607330_4	525904.Tter_0657	2.175e-26	115.0	COG4198@1|root,COG4198@2|Bacteria,2NNV0@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRD1_k127_3607330_0	357808.RoseRS_0271	6.484e-152	505.0	COG1052@1|root,COG1052@2|Bacteria,2GA73@200795|Chloroflexi,374WJ@32061|Chloroflexia	32061|Chloroflexia	CH	D-isomer specific 2-hydroxyacid dehydrogenase catalytic region	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRD1_k127_3607330_1	1089553.Tph_c00160	7.086e-108	362.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia,42EKA@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRD1_k127_3607330_3	1507.HMPREF0262_03707	1.425e-28	117.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,36KGE@31979|Clostridiaceae	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRD1_k127_3607330_2	1049564.TevJSym_aa00340	8.119e-37	143.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1J5PI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRD1_k127_361296_3	1341646.CBMO010000051_gene3438	1.049e-21	105.0	COG2339@1|root,COG2339@2|Bacteria,2GMIX@201174|Actinobacteria,232GB@1762|Mycobacteriaceae	201174|Actinobacteria	S	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease,zf-ribbon_3,zinc_ribbon_2
SRD1_k127_361296_1	1382359.JIAL01000001_gene469	5.038e-63	220.0	COG0225@1|root,COG0225@2|Bacteria,3Y4DM@57723|Acidobacteria,2JJ10@204432|Acidobacteriia	204432|Acidobacteriia	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRD1_k127_361296_0	390989.JOEG01000010_gene561	1.275e-138	453.0	COG0477@1|root,COG2814@2|Bacteria,2I2IS@201174|Actinobacteria,4DCIJ@85008|Micromonosporales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRD1_k127_361296_2	1894.JOER01000057_gene3329	1.123e-40	155.0	COG1764@1|root,COG1764@2|Bacteria,2IFFB@201174|Actinobacteria	201174|Actinobacteria	O	PFAM OsmC family protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRD1_k127_3613037_0	1380347.JNII01000008_gene4408	2.097e-122	401.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria,4EUFI@85013|Frankiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD1_k127_3613037_2	1303518.CCALI_01370	1.216e-82	281.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	sdh	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	adh_short
SRD1_k127_3613037_4	1254432.SCE1572_00795	8.829e-25	110.0	arCOG07238@1|root,34BTI@2|Bacteria,1P13S@1224|Proteobacteria,4354M@68525|delta/epsilon subdivisions,2WZFN@28221|Deltaproteobacteria,2Z21A@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3613037_5	285535.JOEY01000036_gene3945	1.263e-06	61.0	COG3832@1|root,COG3832@2|Bacteria,2IHQS@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRD1_k127_3613037_1	264732.Moth_1000	1.368e-88	314.0	COG0477@1|root,COG2814@2|Bacteria,1TRUT@1239|Firmicutes,25E84@186801|Clostridia,42FN6@68295|Thermoanaerobacterales	186801|Clostridia	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRD1_k127_3613037_3	1128421.JAGA01000002_gene13	6.457e-33	144.0	COG1300@1|root,COG1668@1|root,COG1300@2|Bacteria,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992,ko:K09696	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.115	-	-	ABC2_membrane,ABC2_membrane_2,ABC2_membrane_3,SpoIIM
SRD1_k127_3613037_6	34740.HMEL011780-PA	1.716e-05	49.0	COG1131@1|root,KOG0059@2759|Eukaryota,38BPG@33154|Opisthokonta,3BBB4@33208|Metazoa,3CSBI@33213|Bilateria,41WWW@6656|Arthropoda,3SXDA@50557|Insecta,449S2@7088|Lepidoptera	33208|Metazoa	I	ABC transporter	-	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0033036,GO:0042623,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K05643	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.211	-	-	ABC2_membrane_3,ABC_tran
SRD1_k127_361426_1	525909.Afer_1575	2.02e-51	188.0	COG4213@1|root,COG4213@2|Bacteria,2GKRE@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter substrate-binding protein	xylF	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
SRD1_k127_361426_0	1417296.U879_18800	4.396e-103	341.0	COG1129@1|root,COG4214@1|root,COG1129@2|Bacteria,COG4214@2|Bacteria,1P3ZB@1224|Proteobacteria,2VET1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system, ATPase component	-	-	3.6.3.17	ko:K02056,ko:K10545	ko02010,map02010	M00215,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.4	-	-	ABC_tran,BPD_transp_2
SRD1_k127_361426_2	1101188.KI912155_gene3650	1.471e-41	165.0	COG1129@1|root,COG4214@1|root,COG1129@2|Bacteria,COG4214@2|Bacteria,2GJDV@201174|Actinobacteria,1W8CQ@1268|Micrococcaceae	201174|Actinobacteria	G	ABC transporter	-	-	3.6.3.17	ko:K10545	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.4	-	-	ABC_tran
SRD1_k127_36252_4	234267.Acid_5269	1.768e-57	211.0	COG3391@1|root,COG3391@2|Bacteria,3Y7A2@57723|Acidobacteria	57723|Acidobacteria	S	Cytochrome D1 heme domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
SRD1_k127_36252_2	1121468.AUBR01000034_gene1361	2.827e-111	370.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42HX8@68295|Thermoanaerobacterales	186801|Clostridia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248,ko:K18244	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_36252_1	1121430.JMLG01000002_gene1109	4.522e-128	429.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,260D0@186807|Peptococcaceae	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_36252_6	926569.ANT_04440	3.003e-11	72.0	2DPX2@1|root,333RW@2|Bacteria,2G7A0@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
SRD1_k127_36252_8	227882.SAV_1063	6.318e-05	53.0	28VA1@1|root,2ZHCY@2|Bacteria,2INFH@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
SRD1_k127_36252_5	485913.Krac_10581	2.881e-28	130.0	COG1316@1|root,COG1316@2|Bacteria	2|Bacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRD1_k127_36252_3	1246448.ANAZ01000010_gene3244	2.931e-81	281.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4EHVD@85012|Streptosporangiales	201174|Actinobacteria	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRD1_k127_36252_0	555088.DealDRAFT_3072	1.617e-226	713.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,42KIA@68298|Syntrophomonadaceae	186801|Clostridia	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRD1_k127_36252_7	43354.JOIJ01000004_gene3498	2.119e-05	49.0	COG2185@1|root,COG2185@2|Bacteria,2IFJD@201174|Actinobacteria,4E4D0@85010|Pseudonocardiales	201174|Actinobacteria	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRD1_k127_3629400_0	1120960.ATXG01000001_gene1246	1.599e-171	544.0	COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria,4FKIA@85023|Microbacteriaceae	201174|Actinobacteria	G	Beta-galactosidase trimerisation domain	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
SRD1_k127_3629400_2	1382356.JQMP01000003_gene1686	1.303e-117	401.0	COG0395@1|root,COG0395@2|Bacteria,2G8BX@200795|Chloroflexi,27Z7I@189775|Thermomicrobia	189775|Thermomicrobia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17317	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
SRD1_k127_3629400_1	1382356.JQMP01000003_gene1685	4.665e-125	407.0	COG1175@1|root,COG1175@2|Bacteria,2G6P7@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K10118,ko:K17316	ko02010,map02010	M00196,M00207,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.24,3.A.1.1.28,3.A.1.1.30	-	-	BPD_transp_1
SRD1_k127_3661392_1	756272.Plabr_2388	2.037e-11	66.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD,Excalibur
SRD1_k127_3661392_0	311424.DhcVS_1081	4.736e-223	707.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi,34D8B@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Elongation factor G C-terminus	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRD1_k127_3771595_4	555793.WSK_1788	1.82e-17	87.0	2DD18@1|root,2ZG4B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3771595_3	314278.NB231_01004	2.538e-22	104.0	COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,1S9PQ@1236|Gammaproteobacteria,1X0ZT@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRD1_k127_3771595_5	478741.JAFS01000002_gene68	0.0005723	46.0	COG3189@1|root,COG3189@2|Bacteria,46WCK@74201|Verrucomicrobia,37GW9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRD1_k127_3771595_2	103733.JNYO01000023_gene7071	6.286e-86	298.0	COG1668@1|root,COG1668@2|Bacteria,2I9MY@201174|Actinobacteria,4DYBQ@85010|Pseudonocardiales	201174|Actinobacteria	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRD1_k127_3771595_1	1068980.ARVW01000001_gene5424	3.261e-121	398.0	COG4152@1|root,COG4152@2|Bacteria,2I2DK@201174|Actinobacteria,4DX3X@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRD1_k127_3771595_0	512565.AMIS_24940	2.948e-127	419.0	COG1878@1|root,COG1878@2|Bacteria,2GNFV@201174|Actinobacteria,4DE30@85008|Micromonosporales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRD1_k127_38332_1	1382306.JNIM01000001_gene1374	1.054e-66	230.0	COG0318@1|root,COG0318@2|Bacteria,2G5XA@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD1_k127_38332_0	357808.RoseRS_3551	1.606e-140	460.0	COG2421@1|root,COG2421@2|Bacteria,2G63Y@200795|Chloroflexi,376X6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Acetamidase Formamidase	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
SRD1_k127_38332_2	649747.HMPREF0083_05071	6.245e-54	215.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,26TP2@186822|Paenibacillaceae	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRD1_k127_3847535_0	589865.DaAHT2_1400	2.623e-134	450.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MI79@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRD1_k127_387434_6	2074.JNYD01000002_gene5788	3.087e-05	48.0	COG5012@1|root,COG5012@2|Bacteria,2IEGQ@201174|Actinobacteria	201174|Actinobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
SRD1_k127_387434_1	926550.CLDAP_19790	6.336e-101	336.0	COG1410@1|root,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRD1_k127_387434_0	1298863.AUEP01000009_gene50	4.918e-181	593.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,2HE4H@201174|Actinobacteria,4DTK0@85009|Propionibacteriales	201174|Actinobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
SRD1_k127_387434_2	926550.CLDAP_19800	9.584e-54	200.0	28I8Y@1|root,2Z8BR@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
SRD1_k127_387434_3	452637.Oter_4337	6.194e-15	77.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	mtbC	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
SRD1_k127_387434_5	700598.Niako_6244	3.435e-06	55.0	COG2318@1|root,COG2318@2|Bacteria,4NT5D@976|Bacteroidetes,1J169@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRD1_k127_387434_4	1123023.JIAI01000007_gene1961	1.879e-06	56.0	COG3404@1|root,COG3404@2|Bacteria,2HSFU@201174|Actinobacteria,4EDK3@85010|Pseudonocardiales	201174|Actinobacteria	E	Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
SRD1_k127_3902_5	525909.Afer_1020	4.026e-47	174.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4CNGZ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRD1_k127_3902_0	1304275.C41B8_18181	2.1e-177	572.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_3,Fer4_7
SRD1_k127_3902_8	1123354.AUDR01000015_gene352	3.791e-19	90.0	COG0640@1|root,COG0640@2|Bacteria,1PT7V@1224|Proteobacteria,2VSXK@28216|Betaproteobacteria	28216|Betaproteobacteria	K	regulatory protein, arsR	-	-	-	ko:K22298	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
SRD1_k127_3902_7	1151126.AQYI01000006_gene3215	2.328e-25	107.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4FPHS@85023|Microbacteriaceae	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRD1_k127_3902_2	926560.KE387025_gene3982	1.451e-108	373.0	COG1136@1|root,COG1136@2|Bacteria,1WM2T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_3902_4	926560.KE387025_gene3981	3.997e-79	278.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	devC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRD1_k127_3902_3	926560.KE387025_gene3980	2.569e-79	277.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	devC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRD1_k127_3902_10	1461693.ATO10_13989	4.329e-06	51.0	COG3462@1|root,COG3462@2|Bacteria,1NGXC@1224|Proteobacteria,2UIEV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
SRD1_k127_3902_6	1397699.JNIS01000001_gene994	5.483e-36	155.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli	91061|Bacilli	D	Alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRD1_k127_3902_9	479434.Sthe_1673	1.071e-18	93.0	COG1983@1|root,COG1983@2|Bacteria,2G9IZ@200795|Chloroflexi	200795|Chloroflexi	KT	PFAM PspC domain protein	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
SRD1_k127_3902_11	263358.VAB18032_10885	0.0004725	51.0	COG3087@1|root,COG3087@2|Bacteria,2IS4S@201174|Actinobacteria,4DEVE@85008|Micromonosporales	201174|Actinobacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3902_1	1298880.AUEV01000001_gene5625	2.536e-135	435.0	COG0596@1|root,COG0596@2|Bacteria,2GKT5@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRD1_k127_391649_0	1382306.JNIM01000001_gene3466	4.624e-119	405.0	COG3383@1|root,COG3383@2|Bacteria,2G65S@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM NADH-quinone oxidoreductase, chain G	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRD1_k127_391649_1	671143.DAMO_2695	5.16e-95	333.0	COG1005@1|root,COG1005@2|Bacteria,2NNTT@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRD1_k127_391649_2	926569.ANT_08370	1.317e-53	195.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRD1_k127_3970301_0	1229780.BN381_80233	1.603e-76	278.0	COG4658@1|root,COG4658@2|Bacteria	2|Bacteria	C	electron transport chain	-	-	1.6.5.8	ko:K00347,ko:K03614,ko:K21163	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Complex1_51K,NQR2_RnfD_RnfE,RnfC_N,UnbV_ASPIC,VCBS
SRD1_k127_3970301_2	1267533.KB906735_gene5000	1e-09	63.0	COG2128@1|root,COG2128@2|Bacteria,3Y8RP@57723|Acidobacteria,2JNQT@204432|Acidobacteriia	204432|Acidobacteriia	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3970301_3	446462.Amir_4098	1.562e-09	63.0	COG2128@1|root,COG2128@2|Bacteria,2IFPC@201174|Actinobacteria,4EEQY@85010|Pseudonocardiales	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRD1_k127_3970301_1	35754.JNYJ01000005_gene5510	3.601e-10	61.0	COG2346@1|root,COG2346@2|Bacteria,2IHUK@201174|Actinobacteria,4DM8F@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRD1_k127_3972294_0	1121422.AUMW01000001_gene2482	1.945e-93	314.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,26035@186807|Peptococcaceae	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18870	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRD1_k127_3972294_1	357808.RoseRS_3845	4.347e-56	217.0	COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRD1_k127_3972294_2	330084.JNYZ01000025_gene2726	3.588e-18	85.0	COG1975@1|root,COG1975@2|Bacteria,2IK3Z@201174|Actinobacteria,4E427@85010|Pseudonocardiales	201174|Actinobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C
SRD1_k127_3981361_0	326427.Cagg_3777	5.562e-75	257.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi,376J5@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRD1_k127_3981361_2	452637.Oter_3612	4.02e-05	53.0	2DNCS@1|root,32WU0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_3981361_1	479434.Sthe_1708	3.062e-06	52.0	2DPX2@1|root,333RW@2|Bacteria,2G7A0@200795|Chloroflexi,27Z8D@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
SRD1_k127_3981702_6	309801.trd_A0803	2.039e-45	178.0	COG0697@1|root,COG0697@2|Bacteria,2GBDJ@200795|Chloroflexi,27YYR@189775|Thermomicrobia	189775|Thermomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRD1_k127_3981702_7	1303518.CCALI_00150	4.403e-26	124.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,Guanylate_cyc,NB-ARC,TPR_12,TPR_19
SRD1_k127_3981702_5	1206731.BAGB01000027_gene2946	6.742e-48	182.0	COG1584@1|root,COG1584@2|Bacteria,2IIIX@201174|Actinobacteria,4G7CY@85025|Nocardiaceae	201174|Actinobacteria	S	GPR1/FUN34/yaaH family	-	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
SRD1_k127_3981702_0	351607.Acel_1068	0.0	1156.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4ERWG@85013|Frankiales	201174|Actinobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRD1_k127_3981702_2	1120971.AUCA01000081_gene2376	1.715e-277	876.0	COG2366@1|root,COG2366@2|Bacteria	2|Bacteria	D	antibiotic biosynthetic process	quiP	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRD1_k127_3981702_3	1111479.AXAR01000005_gene608	3.867e-88	310.0	COG0531@1|root,COG0531@2|Bacteria,1VS5Q@1239|Firmicutes,4HTCE@91061|Bacilli	91061|Bacilli	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRD1_k127_3981702_1	1122611.KB904029_gene5414	7.87e-303	947.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4EFY3@85012|Streptosporangiales	201174|Actinobacteria	E	FAD dependent oxidoreductase central domain	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRD1_k127_3981702_8	710686.Mycsm_02785	1.09e-18	101.0	COG2329@1|root,COG2329@2|Bacteria,2I4P2@201174|Actinobacteria,23FCE@1762|Mycobacteriaceae	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRD1_k127_3981702_4	390989.JOEG01000019_gene5909	2.666e-86	289.0	COG0262@1|root,COG0262@2|Bacteria,2GMZV@201174|Actinobacteria,4DE9F@85008|Micromonosporales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRD1_k127_3983142_4	926569.ANT_23310	4.008e-32	125.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRD1_k127_3983142_0	525904.Tter_1614	3.772e-92	327.0	COG0768@1|root,COG0768@2|Bacteria,2NNWR@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	iSSON_1240.SSON_0092	PASTA,PBP_dimer,Transpeptidase
SRD1_k127_3983142_2	1396141.BATP01000041_gene2212	1.681e-81	287.0	COG0770@1|root,COG0770@2|Bacteria,46SDF@74201|Verrucomicrobia,2ITUQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mur ligase middle domain	-	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRD1_k127_3983142_3	1552123.EP57_09125	5.775e-53	201.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,26JRC@186820|Listeriaceae	91061|Bacilli	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRD1_k127_3983142_1	555079.Toce_0950	6.179e-92	317.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,42EZQ@68295|Thermoanaerobacterales	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRD1_k127_3984527_4	671143.DAMO_0086	2.774e-62	237.0	COG0165@1|root,COG0165@2|Bacteria,2NP70@2323|unclassified Bacteria	2|Bacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,4.3.2.1	ko:K01755,ko:K14681	ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230	M00028,M00029,M00844,M00845	R00259,R01086	RC00004,RC00064,RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRD1_k127_3984527_0	644966.Tmar_0539	8.058e-158	510.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3WCR7@538999|Clostridiales incertae sedis	186801|Clostridia	H	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRD1_k127_3984527_5	264732.Moth_1508	6.8e-19	95.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,42GDW@68295|Thermoanaerobacterales	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRD1_k127_3984527_1	1121472.AQWN01000001_gene260	1.121e-128	422.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,2606U@186807|Peptococcaceae	186801|Clostridia	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_3984527_2	429009.Adeg_1831	2.604e-84	288.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia,42ET5@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10565	AA_kinase
SRD1_k127_3984527_3	562970.Btus_2271	1.344e-68	240.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli,277V7@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRD1_k127_3996895_2	1382306.JNIM01000001_gene1224	3.167e-116	383.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2G65W@200795|Chloroflexi	200795|Chloroflexi	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRD1_k127_3996895_0	1122222.AXWR01000035_gene216	1.032e-192	622.0	COG0058@1|root,COG0058@2|Bacteria,1WIR5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Alpha-glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRD1_k127_3996895_1	1089553.Tph_c11790	4.399e-122	408.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,42F2U@68295|Thermoanaerobacterales	186801|Clostridia	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1,HHH_3
SRD1_k127_4009625_3	367299.JOEE01000004_gene1285	2.799e-10	64.0	COG3714@1|root,COG3714@2|Bacteria,2IG79@201174|Actinobacteria,4FGG0@85021|Intrasporangiaceae	201174|Actinobacteria	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
SRD1_k127_4009625_0	316274.Haur_0199	5.23e-36	142.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	dinB	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB
SRD1_k127_4009625_2	1196031.ALEG01000043_gene2263	5.606e-16	87.0	COG3764@1|root,COG3764@2|Bacteria,1V1RS@1239|Firmicutes,4HFWK@91061|Bacilli,1ZFRS@1386|Bacillus	91061|Bacilli	M	COG3764 Sortase (surface protein transpeptidase)	yhcS	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRD1_k127_4009625_1	479433.Caci_5578	1.106e-27	121.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K19720	ko04611,ko04926,ko04933,ko04974,ko05146,map04611,map04926,map04933,map04974,map05146	-	-	-	ko00000,ko00001,ko00536	-	-	-	BNR_2,Peptidase_M23,SLT_2,VCBS
SRD1_k127_4014403_1	880073.Calab_1964	2.852e-26	120.0	COG3382@1|root,COG3382@2|Bacteria,2NPUN@2323|unclassified Bacteria	2|Bacteria	S	B3/4 domain	XK27_07210	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4
SRD1_k127_4014403_0	1218173.BALCAV_0200310	1.281e-112	376.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli,1ZBP0@1386|Bacillus	91061|Bacilli	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRD1_k127_4014996_1	4155.Migut.N02410.1.p	7.049e-06	49.0	COG0303@1|root,KOG2371@2759|Eukaryota,37MHI@33090|Viridiplantae,3G7K1@35493|Streptophyta,44EER@71274|asterids	35493|Streptophyta	H	molybdopterin biosynthesis	-	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008940,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009719,GO:0009725,GO:0009733,GO:0009734,GO:0009755,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0016491,GO:0016661,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0023052,GO:0030151,GO:0032324,GO:0032870,GO:0034641,GO:0036211,GO:0042040,GO:0042221,GO:0042278,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051716,GO:0055086,GO:0055114,GO:0061598,GO:0061599,GO:0065007,GO:0070566,GO:0070887,GO:0071310,GO:0071365,GO:0071495,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1,2.7.7.75	ko:K15376	ko00790,ko01100,ko04727,map00790,map01100,map04727	-	R09726,R09735	RC00002,RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRD1_k127_4014996_2	1123359.AUIQ01000012_gene608	0.0003277	47.0	2ES7N@1|root,33JSD@2|Bacteria,1VMVD@1239|Firmicutes,4HRRE@91061|Bacilli,4B4GE@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4014996_0	1128421.JAGA01000003_gene2751	4.243e-237	747.0	COG0556@1|root,COG0556@2|Bacteria,2NNPM@2323|unclassified Bacteria	2|Bacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702,ko:K08999	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRD1_k127_4015857_5	485913.Krac_11346	2.836e-69	237.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3,AhpC-TSA
SRD1_k127_4015857_6	479434.Sthe_2277	1.133e-67	245.0	COG0639@1|root,COG0639@2|Bacteria,2G8I3@200795|Chloroflexi	200795|Chloroflexi	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRD1_k127_4015857_10	1112217.PPL19_21805	1.23e-19	104.0	COG0642@1|root,COG2205@2|Bacteria,1R82N@1224|Proteobacteria,1S1AN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRD1_k127_4015857_4	1380370.JIBA01000019_gene951	2.246e-78	284.0	COG2172@1|root,COG2208@1|root,COG3447@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,COG3447@2|Bacteria,2GJB0@201174|Actinobacteria,4FG40@85021|Intrasporangiaceae	201174|Actinobacteria	KT	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MASE1,SpoIIE
SRD1_k127_4015857_0	335541.Swol_1716	2.751e-134	461.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1TQXZ@1239|Firmicutes,249E6@186801|Clostridia	186801|Clostridia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,GATase1_like,VWA,VWA_2,VWA_3
SRD1_k127_4015857_3	335541.Swol_1717	6.357e-82	302.0	COG2304@1|root,COG2304@2|Bacteria,1V0C8@1239|Firmicutes,249ZD@186801|Clostridia	186801|Clostridia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
SRD1_k127_4015857_7	383372.Rcas_3819	6.901e-58	211.0	COG1721@1|root,COG1721@2|Bacteria,2GACI@200795|Chloroflexi,375AS@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRD1_k127_4015857_1	1128421.JAGA01000003_gene3250	2.106e-118	398.0	COG0714@1|root,COG0714@2|Bacteria,2NNV8@2323|unclassified Bacteria	2|Bacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRD1_k127_4015857_11	326427.Cagg_0208	2.86e-15	90.0	COG0497@1|root,COG0497@2|Bacteria,2GA8M@200795|Chloroflexi,37598@32061|Chloroflexia	32061|Chloroflexia	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4015857_8	335541.Swol_1722	1.73e-37	161.0	COG1277@1|root,COG1277@2|Bacteria,1V2H6@1239|Firmicutes,25F4G@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRD1_k127_4015857_2	335541.Swol_1723	5.411e-91	317.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRD1_k127_4015857_9	357808.RoseRS_0322	1.18e-26	128.0	COG0318@1|root,COG0318@2|Bacteria,2GBKJ@200795|Chloroflexi,3781K@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4019365_1	290397.Adeh_0418	1.274e-16	94.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1QYFP@1224|Proteobacteria,43CBV@68525|delta/epsilon subdivisions,2X7MN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA
SRD1_k127_4019365_0	1089545.KB913037_gene727	1.854e-95	318.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4DZ59@85010|Pseudonocardiales	201174|Actinobacteria	G	Beta-glucosidase	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRD1_k127_4045858_1	192952.MM_1609	7.536e-10	70.0	COG0577@1|root,arCOG02312@2157|Archaea,2XUEE@28890|Euryarchaeota,2NB5Y@224756|Methanomicrobia	224756|Methanomicrobia	P	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRD1_k127_4045858_0	324602.Caur_2220	2.05e-43	171.0	COG2211@1|root,COG2211@2|Bacteria,2GBJQ@200795|Chloroflexi,376XV@32061|Chloroflexia	32061|Chloroflexia	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4061491_1	1123319.AUBE01000027_gene4804	1.989e-123	416.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRD1_k127_4061491_4	2002.JOEQ01000028_gene8112	2.372e-22	104.0	COG1846@1|root,COG1846@2|Bacteria,2IIAG@201174|Actinobacteria	201174|Actinobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRD1_k127_4061491_3	469371.Tbis_0922	9.934e-39	155.0	COG1102@1|root,COG1102@2|Bacteria,2I8J3@201174|Actinobacteria,4EBNU@85010|Pseudonocardiales	201174|Actinobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
SRD1_k127_4061491_2	1382306.JNIM01000001_gene2314	5.809e-123	413.0	COG0477@1|root,COG2814@2|Bacteria,2GA6K@200795|Chloroflexi	200795|Chloroflexi	P	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRD1_k127_4061491_8	479434.Sthe_3170	0.000447	53.0	COG0457@1|root,COG0515@1|root,COG2199@1|root,COG2203@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	200795|Chloroflexi	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRD1_k127_4061491_7	1347392.CCEZ01000011_gene2430	4.346e-05	49.0	2E4Y1@1|root,32ZRZ@2|Bacteria,1VGPN@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4061491_6	1123360.thalar_03292	3.711e-08	64.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2TS87@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
SRD1_k127_4061491_0	710421.Mycch_2937	1.047e-141	467.0	COG3559@1|root,COG3559@2|Bacteria	2|Bacteria	M	Exporter of polyketide antibiotics	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRD1_k127_4061491_5	1206733.BAGC01000053_gene3072	2.015e-21	98.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4FUJH@85025|Nocardiaceae	201174|Actinobacteria	V	ABC transporter ATP-binding	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRD1_k127_4081237_1	1382306.JNIM01000001_gene466	5.468e-50	187.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRD1_k127_4081237_2	44060.JODL01000031_gene1764	1.337e-05	54.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRD1_k127_4081237_0	1123371.ATXH01000009_gene1077	3.372e-83	287.0	COG0438@1|root,COG0438@2|Bacteria,2GHNP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD1_k127_4083552_5	644282.Deba_1962	3.51e-08	58.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRD1_k127_4083552_0	1382356.JQMP01000003_gene2474	5.363e-292	920.0	COG0653@1|root,COG0653@2|Bacteria,2G603@200795|Chloroflexi,27XJU@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRD1_k127_4083552_1	926550.CLDAP_34520	1.185e-115	382.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRD1_k127_4083552_2	1111479.AXAR01000014_gene1199	2.023e-83	286.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli,277XT@186823|Alicyclobacillaceae	91061|Bacilli	D	ABC transporter	ftsE	GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRD1_k127_4083552_3	699218.HMPREF0889_1052	2.488e-35	147.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4H36P@909932|Negativicutes	909932|Negativicutes	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRD1_k127_4083552_4	552398.HMPREF0866_00382	3.856e-09	66.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,3WGCB@541000|Ruminococcaceae	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRD1_k127_4101428_1	318996.AXAZ01000055_gene6354	1.82e-71	249.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria	1224|Proteobacteria	S	transport system periplasmic component	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
SRD1_k127_4101428_0	189753.AXAS01000041_gene2534	2.623e-89	307.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
SRD1_k127_4107480_2	219305.MCAG_05447	1.136e-30	124.0	COG1801@1|root,COG1801@2|Bacteria,2HU1R@201174|Actinobacteria,4DADR@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRD1_k127_4107480_3	446470.Snas_3455	2.056e-06	57.0	28X37@1|root,2ZJ1Q@2|Bacteria,2HD08@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4107480_1	1470591.BW41_01763	4.065e-37	150.0	COG0300@1|root,COG0300@2|Bacteria,1QU2C@1224|Proteobacteria,2TYY9@28211|Alphaproteobacteria,2K2M7@204457|Sphingomonadales	204457|Sphingomonadales	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD1_k127_4107480_0	867903.ThesuDRAFT_01319	1.223e-46	171.0	COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,24AY7@186801|Clostridia,3WDFJ@538999|Clostridiales incertae sedis	186801|Clostridia	C	Alcohol dehydrogenase GroES-like domain	adhB	-	1.1.1.1,1.1.1.284,1.2.1.46	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00604,R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00188,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRD1_k127_4114433_3	749414.SBI_04493	6.673e-35	139.0	COG0122@1|root,COG0122@2|Bacteria,2GP69@201174|Actinobacteria	201174|Actinobacteria	L	3-methyladenine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4114433_1	316274.Haur_4061	2.475e-38	163.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G8PA@200795|Chloroflexi,376UG@32061|Chloroflexia	32061|Chloroflexia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
SRD1_k127_4114433_0	1128421.JAGA01000002_gene1336	6.172e-50	194.0	COG2514@1|root,COG2514@2|Bacteria,2NRH9@2323|unclassified Bacteria	2|Bacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	catE	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	CppA_C,Glyoxalase
SRD1_k127_4114433_2	298655.KI912266_gene3539	3.179e-36	147.0	COG0204@1|root,COG0204@2|Bacteria,2IAXZ@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRD1_k127_4114433_4	526225.Gobs_1811	5.682e-05	53.0	COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria,4ET39@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
SRD1_k127_4114886_2	1283299.AUKG01000002_gene4064	7.457e-31	129.0	COG1392@1|root,COG1392@2|Bacteria,2GJME@201174|Actinobacteria,4CQ5I@84995|Rubrobacteria	84995|Rubrobacteria	P	Protein of unknown function DUF47	-	-	-	-	-	-	-	-	-	-	-	-	PhoU_div
SRD1_k127_4114886_1	351607.Acel_2027	3.962e-97	332.0	COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria,4ERKR@85013|Frankiales	201174|Actinobacteria	P	phosphate transporter	pit	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	iNJ661.Rv0545c,iNJ661.Rv2281	PHO4
SRD1_k127_4114886_0	525904.Tter_0422	1.416e-170	548.0	COG0114@1|root,COG0114@2|Bacteria,2NS3X@2323|unclassified Bacteria	2|Bacteria	C	Fumarase C C-terminus	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRD1_k127_4114886_3	390989.JOEG01000001_gene5390	2.506e-08	61.0	COG0431@1|root,COG0454@1|root,COG0431@2|Bacteria,COG0456@2|Bacteria,2GNFR@201174|Actinobacteria,4DCI8@85008|Micromonosporales	201174|Actinobacteria	K	FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,FMN_red
SRD1_k127_4132383_2	765420.OSCT_0418	1.126e-50	203.0	COG0745@1|root,COG0745@2|Bacteria,2G6JP@200795|Chloroflexi,3773X@32061|Chloroflexia	32061|Chloroflexia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_4132383_1	562970.Btus_0568	1.074e-56	219.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,4HCQ3@91061|Bacilli,2795G@186823|Alicyclobacillaceae	91061|Bacilli	T	PFAM Osmosensitive K channel His kinase sensor	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
SRD1_k127_4132383_0	525368.HMPREF0591_3789	4.562e-65	238.0	COG4427@1|root,COG4427@2|Bacteria,2HVQW@201174|Actinobacteria,232QG@1762|Mycobacteriaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
SRD1_k127_4132383_3	751944.HALDL1_06175	1.226e-08	63.0	COG0451@1|root,arCOG03019@2157|Archaea,2XTV4@28890|Euryarchaeota,23T5Z@183963|Halobacteria	183963|Halobacteria	M	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRD1_k127_4153249_2	298655.KI912266_gene2769	2.65e-20	93.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4ERYX@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRD1_k127_4153249_1	1047013.AQSP01000017_gene1088	1.53e-84	291.0	COG0604@1|root,COG0604@2|Bacteria,2NP5I@2323|unclassified Bacteria	2|Bacteria	C	PFAM Alcohol dehydrogenase, zinc-binding	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRD1_k127_4153249_0	1458357.BG58_10715	2.595e-113	372.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,1MWIC@1224|Proteobacteria,2W410@28216|Betaproteobacteria,1K5WE@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,MarR_2
SRD1_k127_4163592_1	643648.Slip_0722	1.425e-114	383.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,42K3A@68298|Syntrophomonadaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRD1_k127_4163592_2	1158318.ATXC01000001_gene573	7.545e-79	271.0	COG0217@1|root,COG0217@2|Bacteria,2G3N5@200783|Aquificae	200783|Aquificae	K	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRD1_k127_4163592_4	357808.RoseRS_4363	4.047e-30	125.0	COG0817@1|root,COG0817@2|Bacteria,2G6MA@200795|Chloroflexi,375KP@32061|Chloroflexia	32061|Chloroflexia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRD1_k127_4163592_3	1123355.JHYO01000013_gene1127	1.244e-30	132.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2TSKM@28211|Alphaproteobacteria,36Y1J@31993|Methylocystaceae	28211|Alphaproteobacteria	L	RuvA, C-terminal domain	ruvA	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRD1_k127_4163592_0	1382306.JNIM01000001_gene3853	5.836e-125	414.0	COG2255@1|root,COG2255@2|Bacteria,2G5QQ@200795|Chloroflexi	200795|Chloroflexi	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRD1_k127_4163592_6	1385513.N780_04525	1.593e-07	55.0	2DNS1@1|root,32YVX@2|Bacteria,1VEGC@1239|Firmicutes,4HPC6@91061|Bacilli,2YAY3@289201|Pontibacillus	91061|Bacilli	S	Protein of unknown function (DUF2905)	yrzS	-	-	-	-	-	-	-	-	-	-	-	DUF2905
SRD1_k127_4163592_5	203124.Tery_5077	4.229e-08	64.0	COG0342@1|root,COG0342@2|Bacteria,1G053@1117|Cyanobacteria,1H7U4@1150|Oscillatoriales	1117|Cyanobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRD1_k127_4169560_6	883066.HMPREF9233_00989	1.421e-20	103.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4D359@85005|Actinomycetales	201174|Actinobacteria	K	Crp Fnr family transcriptional regulator	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRD1_k127_4169560_3	1123226.KB899288_gene1070	3.835e-70	253.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,26QBK@186822|Paenibacillaceae	91061|Bacilli	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRD1_k127_4169560_1	756272.Plabr_1015	2.209e-97	328.0	COG2896@1|root,COG2896@2|Bacteria,2IXWS@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
SRD1_k127_4169560_2	997346.HMPREF9374_3292	2.594e-84	286.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HB73@91061|Bacilli,27BNS@186824|Thermoactinomycetaceae	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD1_k127_4169560_4	1408254.T458_23355	3.229e-56	207.0	COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli,26UEW@186822|Paenibacillaceae	91061|Bacilli	I	Belongs to the enoyl-CoA hydratase isomerase family	paaG	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRD1_k127_4169560_0	644966.Tmar_2129	2.633e-152	491.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WCX5@538999|Clostridiales incertae sedis	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRD1_k127_4169560_5	670487.Ocepr_0305	1.537e-45	173.0	COG0500@1|root,COG2226@2|Bacteria,1WIUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRD1_k127_4169560_7	285535.JOEY01000011_gene6082	1.729e-20	100.0	COG2968@1|root,COG2968@2|Bacteria,2GM1U@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF541)	lpqG	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SRD1_k127_4186085_5	1382356.JQMP01000001_gene933	4.978e-70	247.0	COG1175@1|root,COG1175@2|Bacteria,2G86U@200795|Chloroflexi,27YTK@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRD1_k127_4186085_0	1382356.JQMP01000001_gene934	1.844e-212	670.0	COG1653@1|root,COG1653@2|Bacteria,2G891@200795|Chloroflexi,27YX0@189775|Thermomicrobia	189775|Thermomicrobia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
SRD1_k127_4186085_8	1463854.JOHT01000004_gene914	6.998e-26	117.0	COG0395@1|root,COG0395@2|Bacteria,2GKEE@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRD1_k127_4186085_7	580331.Thit_0425	1.092e-34	143.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia,42FWJ@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K10237	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
SRD1_k127_4186085_4	1122915.AUGY01000018_gene6279	5.528e-92	308.0	COG1028@1|root,COG1028@2|Bacteria,1TSWA@1239|Firmicutes,4HBHR@91061|Bacilli,274QR@186822|Paenibacillaceae	91061|Bacilli	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD1_k127_4186085_6	1214101.BN159_6920	1.436e-60	217.0	COG2186@1|root,COG2186@2|Bacteria,2GJ82@201174|Actinobacteria	201174|Actinobacteria	K	gntR family	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRD1_k127_4186085_9	479432.Sros_6243	2.415e-21	96.0	COG3254@1|root,COG3254@2|Bacteria,2INBP@201174|Actinobacteria	201174|Actinobacteria	S	L-rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
SRD1_k127_4186085_2	288000.BBta_1823	7.344e-119	393.0	COG0667@1|root,COG0667@2|Bacteria,1MWGQ@1224|Proteobacteria,2TUJ8@28211|Alphaproteobacteria,3JRSP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldo/keto reductase family	-	-	1.1.1.122	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	M00114	R07675,R08926	RC00066,RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
SRD1_k127_4186085_3	1245469.S58_61300	2.897e-92	314.0	COG3618@1|root,COG3618@2|Bacteria,1P5PT@1224|Proteobacteria,2U3BR@28211|Alphaproteobacteria,3JU4M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
SRD1_k127_4186085_1	1382356.JQMP01000004_gene185	1.72e-149	479.0	COG2042@1|root,COG3376@2|Bacteria,2G83J@200795|Chloroflexi	200795|Chloroflexi	S	High-affinity nickel-transport protein	-	-	-	-	-	-	-	-	-	-	-	-	NicO
SRD1_k127_4186085_10	1123023.JIAI01000003_gene3075	1.765e-08	61.0	COG1540@1|root,COG1540@2|Bacteria,2H5Y7@201174|Actinobacteria,4E2V6@85010|Pseudonocardiales	201174|Actinobacteria	S	5-oxoprolinase (ATP-hydrolyzing) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4194764_6	1232683.ADIMK_0968	2.116e-18	93.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,467GE@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRD1_k127_4194764_4	485913.Krac_8699	9.214e-30	119.0	COG0211@1|root,COG0211@2|Bacteria,2G709@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRD1_k127_4194764_0	1449080.JQMV01000003_gene329	4.283e-101	343.0	COG0536@1|root,COG0536@2|Bacteria,1WIKJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRD1_k127_4194764_3	1499968.TCA2_2070	5.68e-39	158.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,26TNS@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRD1_k127_4194764_5	1232428.CAVO010000016_gene893	9.039e-24	106.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4H585@909932|Negativicutes	909932|Negativicutes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRD1_k127_4194764_7	751945.Theos_1799	2.082e-15	85.0	COG0789@1|root,COG0789@2|Bacteria,1WJ4G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM MerR family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRD1_k127_4194764_1	357808.RoseRS_1276	9.669e-44	179.0	COG2064@1|root,COG2064@2|Bacteria,2G6CF@200795|Chloroflexi,3766N@32061|Chloroflexia	32061|Chloroflexia	NU	PFAM type II secretion system protein	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRD1_k127_4194764_2	574087.Acear_0237	3.871e-42	166.0	COG4965@1|root,COG4965@2|Bacteria,1UZ3V@1239|Firmicutes,25D46@186801|Clostridia	186801|Clostridia	U	type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRD1_k127_4194764_10	457570.Nther_2318	0.0005265	51.0	COG3745@1|root,COG3745@2|Bacteria,1V5FZ@1239|Firmicutes,24I7V@186801|Clostridia	186801|Clostridia	U	Flp pilus assembly protein CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	LysM,RcpC,SAF
SRD1_k127_4194764_9	644966.Tmar_1212	1.151e-05	55.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,3WDPM@538999|Clostridiales incertae sedis	186801|Clostridia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRD1_k127_4194764_8	1380370.JIBA01000003_gene2729	2.113e-07	60.0	COG4961@1|root,COG4961@2|Bacteria,2GWMA@201174|Actinobacteria,4FI0B@85021|Intrasporangiaceae	201174|Actinobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRD1_k127_4198165_2	1283299.AUKG01000001_gene2566	3.365e-107	352.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4CPEP@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_4198165_7	345341.KUTG_01076	3.711e-75	264.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRD1_k127_4198165_4	1382306.JNIM01000001_gene3601	1.626e-88	308.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2G5VX@200795|Chloroflexi	200795|Chloroflexi	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRD1_k127_4198165_14	1341646.CBMO010000123_gene2075	2.733e-09	67.0	COG3080@1|root,COG3080@2|Bacteria,2IMEN@201174|Actinobacteria,239WE@1762|Mycobacteriaceae	201174|Actinobacteria	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdD	-	-	ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1555	Fumarate_red_D
SRD1_k127_4198165_15	443218.AS9A_2958	1.746e-08	63.0	COG3029@1|root,COG3029@2|Bacteria,2IQ2Z@201174|Actinobacteria,23A9K@1762|Mycobacteriaceae	201174|Actinobacteria	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdC	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Fumarate_red_C
SRD1_k127_4198165_3	1122138.AQUZ01000004_gene889	2.179e-93	317.0	COG0479@1|root,COG0479@2|Bacteria,2GJPS@201174|Actinobacteria,4DPU6@85009|Propionibacteriales	201174|Actinobacteria	C	Succinate dehydrogenase fumarate reductase	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
SRD1_k127_4198165_0	1123024.AUII01000011_gene4422	1.27e-199	640.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4DZPA@85010|Pseudonocardiales	201174|Actinobacteria	C	succinate dehydrogenase	frdA	GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0022900,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00244,ko:K00278	ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00115,M00149,M00150,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1552	FAD_binding_2,Succ_DH_flav_C
SRD1_k127_4198165_9	1128421.JAGA01000001_gene2029	5.094e-59	218.0	COG0665@1|root,COG0665@2|Bacteria,2NRT0@2323|unclassified Bacteria	2|Bacteria	E	FAD dependent oxidoreductase	puuB	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
SRD1_k127_4198165_10	1128421.JAGA01000002_gene1079	3.287e-58	216.0	COG2355@1|root,COG2355@2|Bacteria	2|Bacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	pvdM	-	3.4.13.19	ko:K01273,ko:K01274	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRD1_k127_4198165_12	479434.Sthe_2339	2.814e-35	137.0	COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi,27YHA@189775|Thermomicrobia	189775|Thermomicrobia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRD1_k127_4198165_6	266117.Rxyl_2407	3.427e-76	267.0	COG1878@1|root,COG1878@2|Bacteria,2GUSA@201174|Actinobacteria,4CSW4@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRD1_k127_4198165_13	1121448.DGI_0726	5.9e-24	104.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MCF7@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRD1_k127_4198165_5	1278073.MYSTI_02808	1.103e-81	282.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria	1224|Proteobacteria	S	major pilin protein fima	MA20_16755	-	-	-	-	-	-	-	-	-	-	-	DUF1028
SRD1_k127_4198165_8	1968.JOEV01000001_gene7623	2.63e-61	214.0	2BVHN@1|root,32QW3@2|Bacteria,2IKWS@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRD1_k127_4198165_11	1122609.AUGT01000029_gene2602	1.274e-49	188.0	COG0204@1|root,COG0204@2|Bacteria,2IAXZ@201174|Actinobacteria,4DPFR@85009|Propionibacteriales	201174|Actinobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRD1_k127_4198165_1	1120950.KB892707_gene4920	1.209e-156	503.0	COG3875@1|root,COG3875@2|Bacteria,2IAM4@201174|Actinobacteria,4DPEW@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRD1_k127_4198838_0	1123073.KB899241_gene2942	0.0	1448.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1RNST@1236|Gammaproteobacteria,1XCEU@135614|Xanthomonadales	135614|Xanthomonadales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
SRD1_k127_4202067_10	1267535.KB906767_gene5286	8.328e-22	100.0	COG0693@1|root,COG0693@2|Bacteria,3Y9BB@57723|Acidobacteria,2JP5T@204432|Acidobacteriia	204432|Acidobacteriia	S	DJ-1/PfpI family	-	-	4.2.1.103	ko:K18199	ko00930,map00930	-	R05771	RC01467	ko00000,ko00001,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRD1_k127_4202067_8	1211815.CBYP010000023_gene1465	5.151e-36	150.0	COG2852@1|root,COG2852@2|Bacteria,2GSDS@201174|Actinobacteria,4EWH6@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF559)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRD1_k127_4202067_0	1123023.JIAI01000005_gene917	5.813e-278	887.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4DYVW@85010|Pseudonocardiales	201174|Actinobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRD1_k127_4202067_4	1382356.JQMP01000003_gene2318	5.433e-101	340.0	COG4213@1|root,COG4213@2|Bacteria,2G6C4@200795|Chloroflexi,27YS4@189775|Thermomicrobia	189775|Thermomicrobia	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
SRD1_k127_4202067_1	1101188.KI912155_gene3650	3.934e-120	400.0	COG1129@1|root,COG4214@1|root,COG1129@2|Bacteria,COG4214@2|Bacteria,2GJDV@201174|Actinobacteria,1W8CQ@1268|Micrococcaceae	201174|Actinobacteria	G	ABC transporter	-	-	3.6.3.17	ko:K10545	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.4	-	-	ABC_tran
SRD1_k127_4202067_3	104623.Ser39006_04124	2.966e-101	336.0	COG1129@1|root,COG4214@1|root,COG1129@2|Bacteria,COG4214@2|Bacteria,1MVNR@1224|Proteobacteria,1RY9K@1236|Gammaproteobacteria,4053R@613|Serratia	1236|Gammaproteobacteria	G	COG1129 ABC-type sugar transport system, ATPase component	-	-	3.6.3.17	ko:K02056,ko:K10544,ko:K10545	ko02010,map02010	M00215,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.4	-	-	ABC_tran
SRD1_k127_4202067_5	1317124.DW2_03834	1.551e-97	333.0	COG4213@1|root,COG4213@2|Bacteria,1R4J2@1224|Proteobacteria,2TUHF@28211|Alphaproteobacteria,2XKYD@285107|Thioclava	28211|Alphaproteobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
SRD1_k127_4202067_2	298653.Franean1_5188	2.996e-111	375.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,2GJ2S@201174|Actinobacteria,4EV29@85013|Frankiales	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
SRD1_k127_4202067_6	1380355.JNIJ01000050_gene136	1.133e-78	282.0	COG0348@1|root,COG3889@1|root,COG0348@2|Bacteria,COG3889@2|Bacteria,1R9JQ@1224|Proteobacteria,2U3WR@28211|Alphaproteobacteria,3K36U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4202067_7	1382306.JNIM01000001_gene1733	2.998e-55	213.0	arCOG03842@1|root,30WW9@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF929
SRD1_k127_4202067_9	485913.Krac_7869	2.462e-25	120.0	COG4243@1|root,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4,VKOR
SRD1_k127_4209431_1	1121372.AULK01000001_gene2215	1.821e-21	101.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4FPAM@85023|Microbacteriaceae	201174|Actinobacteria	L	SLBB domain	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRD1_k127_4209431_2	543632.JOJL01000027_gene2804	0.0009536	48.0	2AYAN@1|root,31QD6@2|Bacteria,2H0HE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4209431_0	309799.DICTH_1454	1.344e-121	402.0	COG0495@1|root,COG0495@2|Bacteria	2|Bacteria	J	leucyl-tRNA aminoacylation	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRD1_k127_4211490_3	903818.KI912268_gene911	2.473e-36	141.0	COG0253@1|root,COG0253@2|Bacteria,3Y4EC@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRD1_k127_4211490_1	1123023.JIAI01000001_gene6784	3.617e-73	258.0	COG1011@1|root,COG1011@2|Bacteria,2IBB1@201174|Actinobacteria,4E7YD@85010|Pseudonocardiales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRD1_k127_4211490_4	1120950.KB892762_gene5508	3.823e-29	120.0	COG4274@1|root,COG4274@2|Bacteria,2HWQ8@201174|Actinobacteria,4DW30@85009|Propionibacteriales	201174|Actinobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRD1_k127_4211490_0	926566.Terro_0183	6.019e-88	295.0	COG2013@1|root,COG2013@2|Bacteria,3Y2XF@57723|Acidobacteria,2JIE5@204432|Acidobacteriia	204432|Acidobacteriia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
SRD1_k127_4211490_5	1120950.KB892795_gene2293	7.22e-16	86.0	COG0735@1|root,COG0735@2|Bacteria,2IFHB@201174|Actinobacteria,4DRC8@85009|Propionibacteriales	201174|Actinobacteria	P	Ferric uptake regulator family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRD1_k127_4211490_2	1382358.JHVN01000020_gene1372	5.932e-48	176.0	COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,21V2W@150247|Anoxybacillus	91061|Bacilli	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRD1_k127_4213474_0	42256.RradSPS_2424	1.711e-113	393.0	COG0642@1|root,COG4251@1|root,COG5002@1|root,COG0642@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria,4CU46@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
SRD1_k127_4213474_1	485913.Krac_8323	2.402e-53	213.0	COG5002@1|root,COG5002@2|Bacteria,2G8WY@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
SRD1_k127_4213474_2	1121438.JNJA01000003_gene3014	3.074e-21	100.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2M7T3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
SRD1_k127_4219998_5	436229.JOEH01000005_gene3129	8.822e-10	64.0	COG2706@1|root,COG2706@2|Bacteria,2I6SW@201174|Actinobacteria,2NHET@228398|Streptacidiphilus	201174|Actinobacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
SRD1_k127_4219998_0	35754.JNYJ01000009_gene1829	1.508e-54	205.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria,4DAKM@85008|Micromonosporales	201174|Actinobacteria	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRD1_k127_4219998_1	1121423.JONT01000006_gene2462	8.375e-53	194.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_4219998_4	265072.Mfla_1015	8.566e-11	67.0	2DQZQ@1|root,339JR@2|Bacteria,1NNI2@1224|Proteobacteria,2W5R6@28216|Betaproteobacteria,2KN9M@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4219998_6	1286631.X805_07210	1.338e-09	71.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,1KJCZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
SRD1_k127_4219998_2	1121468.AUBR01000036_gene1308	2.092e-33	147.0	COG2203@1|root,COG3437@1|root,COG3605@1|root,COG4936@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3605@2|Bacteria,COG4936@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,42JGC@68295|Thermoanaerobacterales	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,PocR,SBP_bac_3
SRD1_k127_4219998_7	298655.KI912266_gene3275	1.724e-05	57.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,4ESHE@85013|Frankiales	201174|Actinobacteria	T	Two component transcriptional regulator, LuxR family	devR	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD1_k127_4219998_3	485913.Krac_0962	3.958e-21	95.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
SRD1_k127_4248007_4	1463887.KL590018_gene8156	3.532e-67	248.0	COG4934@1|root,COG4934@2|Bacteria,2GMZ8@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase S53	-	-	-	ko:K08677	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_S8,Pro-kuma_activ
SRD1_k127_4248007_7	1122247.C731_4985	3.148e-34	151.0	COG2339@1|root,COG2339@2|Bacteria,2GMIX@201174|Actinobacteria,232GB@1762|Mycobacteriaceae	201174|Actinobacteria	S	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease,zf-ribbon_3,zinc_ribbon_2
SRD1_k127_4248007_6	1068980.ARVW01000001_gene1143	2.231e-42	162.0	COG1280@1|root,COG1280@2|Bacteria,2ICJX@201174|Actinobacteria,4EBWK@85010|Pseudonocardiales	201174|Actinobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRD1_k127_4248007_8	1122622.ATWJ01000009_gene3090	5.077e-34	138.0	COG0454@1|root,COG1042@1|root,COG0456@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4FEVV@85021|Intrasporangiaceae	201174|Actinobacteria	CJ	Multidrug ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRD1_k127_4248007_9	1187851.A33M_1953	1.23e-09	70.0	2CIPC@1|root,2Z9HB@2|Bacteria,1R3W8@1224|Proteobacteria,2TST7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRD1_k127_4248007_2	1382356.JQMP01000003_gene1660	2.258e-89	306.0	COG0842@1|root,COG0842@2|Bacteria,2G6H9@200795|Chloroflexi,27Y1P@189775|Thermomicrobia	189775|Thermomicrobia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRD1_k127_4248007_1	479434.Sthe_2137	1.81e-118	389.0	COG1131@1|root,COG1131@2|Bacteria,2G5RD@200795|Chloroflexi,27XNW@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_4248007_3	1121949.AQXT01000002_gene1623	8.004e-88	297.0	COG1024@1|root,COG1024@2|Bacteria,1NDT7@1224|Proteobacteria,2U2R9@28211|Alphaproteobacteria,43XFU@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD1_k127_4248007_0	945713.IALB_1070	2.154e-206	671.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	pruA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRD1_k127_4248118_0	1306990.BARG01000005_gene284	1.336e-90	307.0	COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria	201174|Actinobacteria	G	Beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
SRD1_k127_4248118_1	1122939.ATUD01000002_gene1481	7.041e-75	262.0	COG0524@1|root,COG0524@2|Bacteria,2GYHF@201174|Actinobacteria,4CQ63@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRD1_k127_4248118_2	1449080.JQMV01000003_gene1298	1.951e-50	185.0	COG1321@1|root,COG1321@2|Bacteria,1WIR2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRD1_k127_4248118_3	1122139.KB907862_gene634	6.285e-12	74.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,1RNA2@1236|Gammaproteobacteria,1XMVS@135619|Oceanospirillales	135619|Oceanospirillales	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
SRD1_k127_4271960_1	1304880.JAGB01000001_gene262	4.76e-23	102.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRD1_k127_4271960_0	246194.CHY_1159	1.181e-153	512.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,42EM0@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRD1_k127_4274476_1	765420.OSCT_1334	5.566e-98	330.0	COG0714@1|root,COG0714@2|Bacteria,2G85W@200795|Chloroflexi,3759A@32061|Chloroflexia	32061|Chloroflexia	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRD1_k127_4274476_4	316274.Haur_0073	3.172e-07	62.0	2E0NP@1|root,32W7Q@2|Bacteria,2G9D8@200795|Chloroflexi,375QK@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
SRD1_k127_4274476_5	67352.JODS01000010_gene4957	8.65e-07	62.0	2CT9V@1|root,32SSX@2|Bacteria,2GKR6@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SRD1_k127_4274476_3	103733.JNYO01000011_gene4878	7.723e-15	84.0	COG5180@1|root,COG5180@2|Bacteria,2GKJ7@201174|Actinobacteria,4E186@85010|Pseudonocardiales	201174|Actinobacteria	A	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
SRD1_k127_4274476_2	1122951.ATUE01000006_gene1204	4.977e-20	94.0	COG0745@1|root,COG0745@2|Bacteria,1N8CM@1224|Proteobacteria,1SZK6@1236|Gammaproteobacteria	1224|Proteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRD1_k127_4274476_0	986075.CathTA2_0959	1.172e-214	679.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRD1_k127_4285057_1	469371.Tbis_2726	7.517e-71	248.0	COG0412@1|root,COG0412@2|Bacteria,2I151@201174|Actinobacteria,4E3BE@85010|Pseudonocardiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRD1_k127_4285057_2	469383.Cwoe_1641	1.494e-11	76.0	COG3835@1|root,COG3835@2|Bacteria	2|Bacteria	KT	positive regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HTH_30
SRD1_k127_4285057_0	997346.HMPREF9374_0894	7.893e-157	506.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,27B4D@186824|Thermoactinomycetaceae	91061|Bacilli	IQ	Beta-ketoacyl synthase, C-terminal domain	fabF3	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRD1_k127_4285057_3	1283287.KB822579_gene1860	1.797e-10	64.0	COG0236@1|root,COG0236@2|Bacteria,2IQ43@201174|Actinobacteria,4DRYW@85009|Propionibacteriales	201174|Actinobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRD1_k127_4286533_2	1298880.AUEV01000003_gene3584	1.594e-30	121.0	COG2346@1|root,COG2346@2|Bacteria,2IKPF@201174|Actinobacteria	201174|Actinobacteria	O	PFAM globin	glbO	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRD1_k127_4286533_1	253839.SSNG_06972	7.155e-62	234.0	COG5504@1|root,COG5504@2|Bacteria,2IBGA@201174|Actinobacteria	201174|Actinobacteria	O	Predicted Zn-dependent protease (DUF2268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2268
SRD1_k127_4286533_0	479434.Sthe_2683	2.355e-72	252.0	COG0477@1|root,COG2814@2|Bacteria,2GBPV@200795|Chloroflexi,27Z1P@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
SRD1_k127_4336965_0	289376.THEYE_A1278	2.252e-144	464.0	COG0473@1|root,COG0473@2|Bacteria,3J0X4@40117|Nitrospirae	40117|Nitrospirae	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRD1_k127_4336965_1	525904.Tter_0600	1.855e-36	139.0	COG1146@1|root,COG1146@2|Bacteria,2NPWS@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S binding domain	fdxA	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_7
SRD1_k127_4336965_2	1463845.JOIG01000004_gene4438	0.0005982	52.0	COG0515@1|root,COG0683@1|root,COG0515@2|Bacteria,COG0683@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4328,PQQ_2,PQQ_3,Peripla_BP_6,Pkinase,TPR_12
SRD1_k127_4350970_1	1183438.GKIL_3787	2.128e-63	222.0	COG0034@1|root,COG0034@2|Bacteria,1G1C9@1117|Cyanobacteria	1117|Cyanobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRD1_k127_4350970_0	483219.LILAB_21205	2.433e-83	295.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2WIXY@28221|Deltaproteobacteria,2YTTG@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844	AIRS,AIRS_C
SRD1_k127_4358331_1	931627.MycrhDRAFT_1688	1.892e-83	282.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,238CW@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_4358331_0	931627.MycrhDRAFT_1689	1.109e-89	304.0	COG3173@1|root,COG3173@2|Bacteria,2GNNV@201174|Actinobacteria,235T8@1762|Mycobacteriaceae	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRD1_k127_4358331_2	1214101.BN159_8033	9.469e-22	104.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	mutT	-	3.1.3.73,3.6.1.55,5.4.2.11,5.4.2.12	ko:K01834,ko:K02226,ko:K03574,ko:K15634	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003,M00122	R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000,ko03400,ko04131,ko04147	-	-	-	His_Phos_1,NUDIX
SRD1_k127_4359251_0	525904.Tter_1052	1.258e-166	531.0	COG0465@1|root,COG0465@2|Bacteria,2NNQ5@2323|unclassified Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRD1_k127_4359251_3	1452536.JARE01000048_gene921	1.348e-29	132.0	COG5495@1|root,COG5495@2|Bacteria,2IK43@201174|Actinobacteria,4FRXI@85023|Microbacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520
SRD1_k127_4359251_1	502025.Hoch_2431	2.356e-98	331.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,2YU2N@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRD1_k127_4359251_2	479434.Sthe_0699	2.083e-79	286.0	COG0414@1|root,COG0414@2|Bacteria,2G64N@200795|Chloroflexi,27XI9@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRD1_k127_4360762_0	1382306.JNIM01000001_gene971	4.213e-46	189.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
SRD1_k127_4360762_1	1382306.JNIM01000001_gene970	9.319e-31	129.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRD1_k127_43807_0	264732.Moth_2463	3.972e-263	820.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,42EYD@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRD1_k127_43807_1	1151116.Q7S_21035	4.216e-204	640.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,3FGD2@34037|Rahnella	1236|Gammaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRD1_k127_43807_4	1121472.AQWN01000002_gene2039	1.003e-44	163.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,2620M@186807|Peptococcaceae	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRD1_k127_43807_2	555088.DealDRAFT_1523	1.728e-67	242.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,42JTZ@68298|Syntrophomonadaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRD1_k127_43807_3	562970.Btus_0154	5.432e-57	207.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,2789A@186823|Alicyclobacillaceae	91061|Bacilli	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRD1_k127_43807_6	316274.Haur_4917	7.824e-20	95.0	COG0089@1|root,COG0089@2|Bacteria,2G73T@200795|Chloroflexi,375Y1@32061|Chloroflexia	32061|Chloroflexia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRD1_k127_43807_5	1121423.JONT01000027_gene655	1.341e-33	136.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,260NI@186807|Peptococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRD1_k127_4385003_3	644283.Micau_5489	2.281e-29	128.0	COG2852@1|root,COG2852@2|Bacteria,2GN40@201174|Actinobacteria,4DDX1@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRD1_k127_4385003_5	985867.AEWF01000003_gene1003	2.942e-18	93.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2TS4E@28211|Alphaproteobacteria,47FMI@766|Rickettsiales	766|Rickettsiales	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRD1_k127_4385003_1	525904.Tter_0912	6.849e-77	273.0	COG0195@1|root,COG0195@2|Bacteria,2NNV1@2323|unclassified Bacteria	2|Bacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRD1_k127_4385003_4	1123226.KB899277_gene1173	4.591e-19	89.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli,26YIS@186822|Paenibacillaceae	91061|Bacilli	K	Nucleic-acid-binding protein	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SRD1_k127_4385003_0	1123371.ATXH01000025_gene203	7.236e-178	578.0	COG0532@1|root,COG0532@2|Bacteria,2GGT0@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
SRD1_k127_4385003_2	997346.HMPREF9374_0699	9.013e-30	123.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,27C3I@186824|Thermoactinomycetaceae	91061|Bacilli	J	Ribosome-binding factor A	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRD1_k127_4401492_0	234267.Acid_6996	7.441e-312	972.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,3Y415@57723|Acidobacteria	57723|Acidobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
SRD1_k127_4401492_1	710421.Mycch_2936	4.743e-120	392.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,23350@1762|Mycobacteriaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRD1_k127_4411761_0	1430331.EP10_18140	1.173e-47	174.0	COG1028@1|root,COG1028@2|Bacteria,1V14I@1239|Firmicutes,4HCT7@91061|Bacilli,1WFZ8@129337|Geobacillus	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRD1_k127_4411761_3	928724.SacglDRAFT_00423	1.66e-24	113.0	COG2030@1|root,COG2030@2|Bacteria,2IFCJ@201174|Actinobacteria,4E4UR@85010|Pseudonocardiales	201174|Actinobacteria	I	dehydratase	hadB	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRD1_k127_4411761_5	1340434.AXVA01000006_gene4355	6.341e-11	74.0	COG2030@1|root,COG2030@2|Bacteria,1V4PQ@1239|Firmicutes,4HGYW@91061|Bacilli,1ZFZ6@1386|Bacillus	91061|Bacilli	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRD1_k127_4411761_2	1121422.AUMW01000018_gene1909	1.303e-27	115.0	COG3255@1|root,COG3255@2|Bacteria,1VFEY@1239|Firmicutes,24QXQ@186801|Clostridia,263BY@186807|Peptococcaceae	186801|Clostridia	I	sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRD1_k127_4411761_4	1223542.GM1_011_00090	3.665e-17	87.0	COG2867@1|root,COG2867@2|Bacteria,2I47G@201174|Actinobacteria,4GH8A@85026|Gordoniaceae	201174|Actinobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRD1_k127_4411761_1	1128421.JAGA01000002_gene119	1.516e-41	156.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRD1_k127_4421941_0	1173020.Cha6605_0891	3.192e-68	260.0	COG3250@1|root,COG3250@2|Bacteria,1G27N@1117|Cyanobacteria	1117|Cyanobacteria	G	glycoside hydrolase family 2, TIM barrel	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRD1_k127_4424278_1	1379698.RBG1_1C00001G0452	1.122e-66	254.0	COG0479@1|root,COG0479@2|Bacteria,2NPY8@2323|unclassified Bacteria	2|Bacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB1	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0247c	Fer2_3,Fer4_8
SRD1_k127_4424278_0	1267534.KB906759_gene1792	4e-214	691.0	COG1053@1|root,COG1053@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRD1_k127_4424278_2	604331.AUHY01000058_gene1343	4.446e-66	233.0	2CEY7@1|root,2Z8CG@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4424278_3	35754.JNYJ01000144_gene2342	2.05e-18	91.0	2A18G@1|root,30PEU@2|Bacteria,2IGED@201174|Actinobacteria,4DD94@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4426601_2	338969.Rfer_3526	1.092e-29	121.0	COG3320@1|root,COG4221@1|root,COG3320@2|Bacteria,COG4221@2|Bacteria,1QSHC@1224|Proteobacteria,2VKRX@28216|Betaproteobacteria,4AB29@80864|Comamonadaceae	28216|Betaproteobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4,adh_short
SRD1_k127_4426601_3	979556.MTES_3632	5.909e-07	63.0	2EGCD@1|root,33A46@2|Bacteria,2HKUV@201174|Actinobacteria,4FQBT@85023|Microbacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
SRD1_k127_4426601_0	868595.Desca_2524	1.727e-170	554.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,260I5@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRD1_k127_4426601_1	1035195.HMPREF9997_01075	8.478e-30	130.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,22JNF@1653|Corynebacteriaceae	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRD1_k127_4451637_6	1449347.JQLN01000006_gene3088	4.184e-07	62.0	COG0823@1|root,COG3468@1|root,COG0823@2|Bacteria,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	PD40,REJ,TIG,VWA,YbaB_DNA_bd
SRD1_k127_4451637_5	498761.HM1_0309	2.518e-21	108.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia	186801|Clostridia	L	Hydrolase, nudix family	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRD1_k127_4451637_1	479434.Sthe_2003	6.084e-147	500.0	COG0439@1|root,COG0439@2|Bacteria,2G62X@200795|Chloroflexi	200795|Chloroflexi	I	Carbamoyl-phosphate synthetase large chain domain protein	accC	-	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01961,ko:K01968,ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00376,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRD1_k127_4451637_0	386456.JQKN01000017_gene869	5.995e-156	518.0	COG5016@1|root,arCOG02095@2157|Archaea,2XV3W@28890|Euryarchaeota,23PD1@183925|Methanobacteria	183925|Methanobacteria	C	TIGRFAM oxaloacetate decarboxylase alpha subunit	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
SRD1_k127_4451637_4	479434.Sthe_1820	5.163e-46	170.0	COG0041@1|root,COG0041@2|Bacteria,2G6JS@200795|Chloroflexi,27YJ0@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRD1_k127_4451637_2	290397.Adeh_2467	1.807e-119	402.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2YU6X@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
SRD1_k127_4451637_3	1122138.AQUZ01000012_gene6041	1.032e-67	243.0	2C1EG@1|root,2Z7MZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4454856_2	405948.SACE_5619	2.708e-102	336.0	COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria,4DXJB@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SRD1_k127_4454856_7	1463917.JODC01000002_gene860	3.145e-80	285.0	COG0685@1|root,COG0685@2|Bacteria,2I92A@201174|Actinobacteria	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRD1_k127_4454856_4	1380356.JNIK01000016_gene3793	4.331e-101	345.0	COG1409@1|root,COG1409@2|Bacteria,2GK31@201174|Actinobacteria	201174|Actinobacteria	M	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRD1_k127_4454856_0	1306174.JODP01000001_gene5144	4.288e-146	481.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
SRD1_k127_4454856_6	1306174.JODP01000001_gene5145	7.327e-82	280.0	COG1177@1|root,COG1177@2|Bacteria,2GM0E@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type spermidine putrescine transport system, permease component II	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
SRD1_k127_4454856_3	1246995.AFR_20940	9.808e-102	340.0	COG4132@1|root,COG4132@2|Bacteria,2GNDF@201174|Actinobacteria,4DDI7@85008|Micromonosporales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
SRD1_k127_4454856_1	543632.JOJL01000036_gene3033	1.885e-131	429.0	COG1840@1|root,COG1840@2|Bacteria,2GJFH@201174|Actinobacteria,4DC3Y@85008|Micromonosporales	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6
SRD1_k127_4454856_8	1121019.AUMN01000002_gene374	4.171e-56	205.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,1WAMW@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRD1_k127_4454856_5	397278.JOJN01000002_gene637	1.498e-88	301.0	COG5012@1|root,COG5012@2|Bacteria,2IEGQ@201174|Actinobacteria,4DTAH@85009|Propionibacteriales	201174|Actinobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
SRD1_k127_4465419_6	525904.Tter_1026	3.616e-07	55.0	COG3847@1|root,COG3847@2|Bacteria	2|Bacteria	U	Flp Fap pilin component	pilA	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Class_IIIsignal,Flp_Fap
SRD1_k127_4465419_7	555088.DealDRAFT_0812	3.64e-06	58.0	COG3745@1|root,COG3745@2|Bacteria,1V5FZ@1239|Firmicutes,24I7V@186801|Clostridia,42KSY@68298|Syntrophomonadaceae	186801|Clostridia	U	TIGRFAM Flp pilus assembly protein CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
SRD1_k127_4465419_0	688245.CtCNB1_2095	1.797e-125	417.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2VJWJ@28216|Betaproteobacteria,4ABAY@80864|Comamonadaceae	28216|Betaproteobacteria	U	type II secretion system protein E	cpaF1	-	-	ko:K02283,ko:K20527	ko02024,map02024	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.7.4	-	-	T2SSE
SRD1_k127_4465419_3	1121428.DESHY_10183___1	4.445e-57	211.0	COG4965@1|root,COG4965@2|Bacteria,1UZ3V@1239|Firmicutes,25D46@186801|Clostridia,260VX@186807|Peptococcaceae	186801|Clostridia	U	PFAM type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRD1_k127_4465419_1	926569.ANT_20670	1.351e-62	226.0	COG2064@1|root,COG2064@2|Bacteria,2G6CF@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM type II secretion system protein	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRD1_k127_4465419_4	1382356.JQMP01000003_gene2008	2.011e-40	168.0	COG2323@1|root,COG2323@2|Bacteria,2GBW1@200795|Chloroflexi,27YMQ@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
SRD1_k127_4465419_2	797303.Natpe_0714	3.768e-58	210.0	COG0596@1|root,arCOG01648@2157|Archaea	797303.Natpe_0714|-	IQ	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4465419_5	479434.Sthe_0522	1.428e-20	95.0	COG1430@1|root,COG1430@2|Bacteria,2G794@200795|Chloroflexi,27YP7@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRD1_k127_448759_0	224325.AF_1753	6.042e-43	167.0	COG2267@1|root,arCOG01650@2157|Archaea,2XYG5@28890|Euryarchaeota	28890|Euryarchaeota	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRD1_k127_448759_2	485913.Krac_6791	1.002e-24	107.0	COG2261@1|root,COG2261@2|Bacteria,2G9IB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Transglycosylase-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRD1_k127_448759_1	1121946.AUAX01000027_gene7931	4.74e-39	151.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4D9JZ@85008|Micromonosporales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD1_k127_449185_0	298654.FraEuI1c_0741	2.805e-67	234.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4ERS8@85013|Frankiales	201174|Actinobacteria	E	aminotransferase class I and II	-	-	2.6.1.1,2.6.1.17,2.6.1.2,2.6.1.66	ko:K00812,ko:K10907,ko:K14260,ko:K14261,ko:K14267	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R04475,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRD1_k127_449185_2	351607.Acel_0591	2.434e-30	131.0	COG0517@1|root,COG1592@1|root,COG0517@2|Bacteria,COG1592@2|Bacteria,2GKSH@201174|Actinobacteria,4ETKN@85013|Frankiales	201174|Actinobacteria	C	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRD1_k127_449185_1	751945.Theos_0249	3.156e-66	246.0	COG1171@1|root,COG1171@2|Bacteria,1WI3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD1_k127_449185_3	1280390.CBQR020000102_gene2590	3.657e-27	119.0	COG0697@1|root,COG0697@2|Bacteria,1UYSM@1239|Firmicutes,4HFBU@91061|Bacilli,26SAB@186822|Paenibacillaceae	91061|Bacilli	EG	of the drug metabolite transporter (DMT) superfamily	yoaV5	-	-	-	-	-	-	-	-	-	-	-	EamA
SRD1_k127_4514549_15	1121877.JQKF01000017_gene185	1.596e-50	191.0	28MYG@1|root,2ZB5C@2|Bacteria,2H19V@201174|Actinobacteria,4CN08@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4514549_12	525904.Tter_0599	4.045e-57	210.0	COG0506@1|root,COG0506@2|Bacteria,2NPED@2323|unclassified Bacteria	2|Bacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRD1_k127_4514549_17	189753.AXAS01000002_gene5413	6.627e-43	169.0	COG3391@1|root,COG3391@2|Bacteria,1RFWG@1224|Proteobacteria,2U7T8@28211|Alphaproteobacteria,3K2MV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4514549_16	105420.BBPO01000027_gene6925	1.222e-45	175.0	2DPF3@1|root,331TJ@2|Bacteria,2IK5R@201174|Actinobacteria,2NKS8@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4514549_22	31964.CMS0652	2.545e-26	112.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4FPHS@85023|Microbacteriaceae	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRD1_k127_4514549_0	1410634.JHVD01000027_gene1655	6.03e-322	1009.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DPNE@85009|Propionibacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
SRD1_k127_4514549_30	909663.KI867150_gene4	0.0002635	53.0	COG3462@1|root,COG3462@2|Bacteria,1Q55M@1224|Proteobacteria,42WZ8@68525|delta/epsilon subdivisions,2WSP8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
SRD1_k127_4514549_19	926569.ANT_26550	5.893e-38	151.0	COG3212@1|root,COG3212@2|Bacteria	2|Bacteria	T	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
SRD1_k127_4514549_29	953739.SVEN_0518	0.0002224	46.0	297DF@1|root,2ZUKY@2|Bacteria,2GRA4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4514549_27	1123226.KB899279_gene2443	2.906e-07	62.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,26SZA@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRD1_k127_4514549_28	44060.JODL01000031_gene1764	1.186e-06	55.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRD1_k127_4514549_2	525904.Tter_0670	1.163e-121	398.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD1_k127_4514549_3	234267.Acid_6457	5.137e-121	406.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
SRD1_k127_4514549_25	697281.Mahau_2221	8.44e-17	91.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,42G4P@68295|Thermoanaerobacterales	186801|Clostridia	I	PFAM phosphoesterase, PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRD1_k127_4514549_26	1463917.JODC01000001_gene204	3.489e-13	76.0	COG1366@1|root,COG1366@2|Bacteria,2GVID@201174|Actinobacteria	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	MEDS,STAS_2
SRD1_k127_4514549_7	1449976.KALB_4798	7.152e-78	273.0	COG2172@1|root,COG2172@2|Bacteria,2GKU6@201174|Actinobacteria,4E0A3@85010|Pseudonocardiales	201174|Actinobacteria	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS
SRD1_k127_4514549_5	67356.KL575607_gene8906	2.037e-86	298.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRD1_k127_4514549_14	1121946.AUAX01000003_gene1482	1.062e-50	195.0	2C56P@1|root,2ZJ2W@2|Bacteria,2IKDI@201174|Actinobacteria,4DDQZ@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4514549_6	35754.JNYJ01000022_gene8131	5.704e-85	300.0	COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRD1_k127_4514549_10	525904.Tter_1098	8.55e-66	232.0	COG0745@1|root,COG0745@2|Bacteria,2NQA9@2323|unclassified Bacteria	2|Bacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_4514549_23	1283283.ATXA01000001_gene487	2.873e-18	89.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2,YCII
SRD1_k127_4514549_8	33876.JNXY01000033_gene2222	3.26e-72	256.0	COG1305@1|root,COG1305@2|Bacteria,2IIM2@201174|Actinobacteria,4DGSH@85008|Micromonosporales	201174|Actinobacteria	E	Bacterial transglutaminase-like N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
SRD1_k127_4514549_4	1121272.KB903249_gene1705	1.479e-88	312.0	COG1305@1|root,COG1305@2|Bacteria,2GMD7@201174|Actinobacteria,4DDU8@85008|Micromonosporales	201174|Actinobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
SRD1_k127_4514549_1	357808.RoseRS_3276	2.471e-170	564.0	COG2308@1|root,COG2308@2|Bacteria,2GACA@200795|Chloroflexi,37575@32061|Chloroflexia	32061|Chloroflexia	S	A circularly permuted ATPgrasp	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SRD1_k127_4514549_21	644968.DFW101_0377	2.527e-26	120.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,42PS4@68525|delta/epsilon subdivisions,2WM4V@28221|Deltaproteobacteria,2M95K@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
SRD1_k127_4514549_13	1123508.JH636443_gene4681	4.137e-54	200.0	COG1305@1|root,COG1305@2|Bacteria,2IYAD@203682|Planctomycetes	203682|Planctomycetes	E	transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
SRD1_k127_4514549_11	266117.Rxyl_1776	1.567e-63	236.0	COG1707@1|root,COG1707@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06862	-	-	-	-	ko00000	-	-	-	ACT
SRD1_k127_4514549_9	479433.Caci_5126	3.099e-66	236.0	COG1414@1|root,COG1414@2|Bacteria,2GJAZ@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	gylR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRD1_k127_4514549_20	1869.MB27_15525	1.123e-32	131.0	COG3412@1|root,COG3412@2|Bacteria,2IHRN@201174|Actinobacteria,4DG22@85008|Micromonosporales	201174|Actinobacteria	S	PTS system fructose IIA component	dhaM	-	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	EIIA-man,PTS-HPr
SRD1_k127_4514549_24	867903.ThesuDRAFT_00838	1.974e-17	86.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,3WDM8@538999|Clostridiales incertae sedis	186801|Clostridia	G	PFAM PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
SRD1_k127_4514549_18	1380358.JADJ01000027_gene1643	3.48e-41	159.0	COG1080@1|root,COG4668@1|root,COG1080@2|Bacteria,COG4668@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1XNNQ@135619|Oceanospirillales	135619|Oceanospirillales	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr,PTS_EIIA_2
SRD1_k127_4517652_0	1382356.JQMP01000003_gene2075	4.348e-74	257.0	COG0458@1|root,COG0458@2|Bacteria,2G5NX@200795|Chloroflexi,27XRT@189775|Thermomicrobia	189775|Thermomicrobia	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRD1_k127_4517652_2	644282.Deba_2876	1.436e-46	177.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SRD1_k127_4517652_1	477974.Daud_1300	5.104e-59	211.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,260Y3@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRD1_k127_452916_0	479434.Sthe_0463	2.509e-121	405.0	COG0821@1|root,COG0821@2|Bacteria,2G5SC@200795|Chloroflexi,27XZE@189775|Thermomicrobia	189775|Thermomicrobia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRD1_k127_452916_3	401526.TcarDRAFT_2101	1.793e-49	190.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4H220@909932|Negativicutes	909932|Negativicutes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
SRD1_k127_452916_1	1380356.JNIK01000016_gene3860	6.002e-93	330.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4ERMJ@85013|Frankiales	201174|Actinobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2870c	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRD1_k127_452916_4	635013.TherJR_1363	1.93e-32	143.0	COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,25HJP@186801|Clostridia,267IB@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRD1_k127_452916_2	926550.CLDAP_41140	3.263e-72	250.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRD1_k127_4532899_1	498848.TaqDRAFT_4204	1.592e-52	200.0	COG1494@1|root,COG1494@2|Bacteria,1WI3D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRD1_k127_4532899_0	246194.CHY_0125	1.365e-109	361.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,42F21@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
SRD1_k127_4559412_2	882083.SacmaDRAFT_4947	0.0009687	42.0	COG1082@1|root,COG1082@2|Bacteria,2GJKJ@201174|Actinobacteria,4E0PV@85010|Pseudonocardiales	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRD1_k127_4559412_1	867845.KI911784_gene292	1.265e-32	139.0	COG0500@1|root,COG2226@2|Bacteria,2G948@200795|Chloroflexi,376TJ@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRD1_k127_4559412_0	1313172.YM304_41890	1.529e-97	334.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD1_k127_4587804_6	228405.HNE_1129	3.656e-14	73.0	COG1680@1|root,COG1680@2|Bacteria,1QD0J@1224|Proteobacteria,2U189@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRD1_k127_4587804_1	1536774.H70357_13430	5.762e-92	329.0	COG0726@1|root,COG2755@1|root,COG3250@1|root,COG3693@1|root,COG0726@2|Bacteria,COG2755@2|Bacteria,COG3250@2|Bacteria,COG3693@2|Bacteria,1UIPP@1239|Firmicutes,4ISP9@91061|Bacilli,2775K@186822|Paenibacillaceae	91061|Bacilli	G	PFAM glycoside hydrolase family 10	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Lipase_GDSL_2,Polysacc_deac_1,SLH
SRD1_k127_4587804_3	666684.AfiDRAFT_0399	1.178e-34	134.0	2C3CF@1|root,32RRR@2|Bacteria,1MZUG@1224|Proteobacteria,2UC1Q@28211|Alphaproteobacteria,3K03D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3175
SRD1_k127_4587804_4	1068978.AMETH_3985	1.476e-22	102.0	COG1359@1|root,COG5485@1|root,COG1359@2|Bacteria,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	ko:K15945	ko01057,ko01130,map01057,map01130	-	R09330	RC00046	ko00000,ko00001	-	-	-	ABM,SnoaL
SRD1_k127_4587804_0	525904.Tter_2662	3.066e-151	488.0	COG2267@1|root,COG2267@2|Bacteria,2NRKH@2323|unclassified Bacteria	2|Bacteria	I	Alpha/beta hydrolase family	fpaP	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRD1_k127_4587804_7	937777.Deipe_2119	2.409e-10	65.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRD1_k127_4587804_8	35754.JNYJ01000015_gene8477	9.74e-08	62.0	2AVGH@1|root,31M8P@2|Bacteria,2IMUQ@201174|Actinobacteria,4DEJS@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4587804_2	926569.ANT_04120	2.231e-42	162.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi	200795|Chloroflexi	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRD1_k127_4587804_5	1121937.AUHJ01000010_gene1587	6.613e-18	84.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,464J3@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRD1_k127_459352_4	479434.Sthe_0729	1.679e-23	100.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi,27XEZ@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD1_k127_459352_2	861299.J421_1984	5.395e-25	112.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
SRD1_k127_459352_1	1150398.JIBJ01000013_gene2548	4.397e-39	150.0	2EN3K@1|root,33FRP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_459352_3	635013.TherJR_0815	8.36e-24	111.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia,261Y1@186807|Peptococcaceae	186801|Clostridia	I	PFAM PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRD1_k127_459352_5	76636.JOEC01000001_gene372	0.0005415	48.0	COG1359@1|root,COG1359@2|Bacteria,2GR78@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRD1_k127_459352_0	525904.Tter_2842	6.839e-204	644.0	COG2146@1|root,COG2220@1|root,COG2146@2|Bacteria,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	1.14.18.2	ko:K08080,ko:K14952	ko00520,ko05152,map00520,map05152	-	R01115,R01803	RC00157	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_3,Rieske
SRD1_k127_4693944_3	370438.PTH_0502	3.81e-54	197.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,26184@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRD1_k127_4693944_1	552811.Dehly_1121	4.593e-88	301.0	COG0002@1|root,COG0002@2|Bacteria,2G6D0@200795|Chloroflexi,34CPV@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRD1_k127_4693944_6	586416.GZ22_07755	1.25e-32	142.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli	91061|Bacilli	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14110,iYO844.BSU34860	PRA-CH,PRA-PH
SRD1_k127_4693944_0	251221.35214889	2.804e-101	335.0	COG0107@1|root,COG0107@2|Bacteria,1G18S@1117|Cyanobacteria	1117|Cyanobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRD1_k127_4693944_5	1122915.AUGY01000189_gene2043	3.654e-47	184.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HFXQ@91061|Bacilli,26TP6@186822|Paenibacillaceae	91061|Bacilli	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRD1_k127_4693944_4	519989.ECTPHS_01509	5.126e-50	184.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1WVVY@135613|Chromatiales	135613|Chromatiales	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRD1_k127_4693944_2	1033810.HLPCO_001848	2.948e-64	226.0	COG0141@1|root,COG0141@2|Bacteria,2NNTS@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRD1_k127_4698650_0	1051632.TPY_1184	5.976e-128	419.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3WCC2@538999|Clostridiales incertae sedis	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRD1_k127_4698650_1	1499685.CCFJ01000042_gene2513	1.136e-31	138.0	COG0266@1|root,COG0266@2|Bacteria,1V0IH@1239|Firmicutes,4HCNZ@91061|Bacilli,1ZDTY@1386|Bacillus	91061|Bacilli	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRD1_k127_4703503_2	1121105.ATXL01000016_gene1637	1.199e-38	152.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,4B2A4@81852|Enterococcaceae	91061|Bacilli	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRD1_k127_4703503_0	479434.Sthe_1056	9.318e-107	361.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi,27XI1@189775|Thermomicrobia	189775|Thermomicrobia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRD1_k127_4703503_1	1071073.KI530535_gene450	3.857e-57	211.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,1ZBYM@1386|Bacillus	91061|Bacilli	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRD1_k127_4703503_3	547163.BN979_00893	1.363e-31	126.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,232U8@1762|Mycobacteriaceae	201174|Actinobacteria	E	Methionine aminopeptidase	mapA	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016020,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRD1_k127_4711750_1	880072.Desac_0080	0.0001777	46.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WSGG@28221|Deltaproteobacteria,2MSG3@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRD1_k127_4711750_0	760568.Desku_1728	1.455e-68	255.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia,262BK@186807|Peptococcaceae	186801|Clostridia	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRD1_k127_4719751_1	760568.Desku_1708	1.352e-34	141.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,2617E@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRD1_k127_4719751_3	485913.Krac_12241	8.215e-20	92.0	COG2331@1|root,COG2331@2|Bacteria,2G752@200795|Chloroflexi	200795|Chloroflexi	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRD1_k127_4719751_2	1131814.JAFO01000001_gene430	2.359e-34	134.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,3EZPV@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	Thioredoxin-like domain	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRD1_k127_4719751_0	1122963.AUHB01000005_gene2691	8.938e-54	198.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,36Y2G@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRD1_k127_4755039_0	211114.JOEF01000037_gene6902	0.0	1273.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4DYUS@85010|Pseudonocardiales	201174|Actinobacteria	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRD1_k127_4768939_0	479434.Sthe_1091	3.616e-295	943.0	COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi,27XZS@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRD1_k127_4768939_1	1232410.KI421421_gene3518	1.723e-117	397.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,1MVKX@1224|Proteobacteria,42QDJ@68525|delta/epsilon subdivisions,2WIJ9@28221|Deltaproteobacteria,43S4B@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Alpha-amylase domain	treS	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
SRD1_k127_4887167_0	326427.Cagg_2706	2.457e-217	693.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi,374SV@32061|Chloroflexia	32061|Chloroflexia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRD1_k127_4896733_0	401526.TcarDRAFT_0437	9.207e-109	362.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4H28M@909932|Negativicutes	909932|Negativicutes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRD1_k127_4896733_1	983917.RGE_30170	2.779e-35	149.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	-	-	-	ko:K03830	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,YiiD_C
SRD1_k127_4896733_2	742738.HMPREF9460_00192	5.422e-23	109.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,2696F@186813|unclassified Clostridiales	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRD1_k127_4905448_1	1094980.Mpsy_1961	7.607e-88	294.0	COG0262@1|root,arCOG01490@2157|Archaea,2XYCD@28890|Euryarchaeota	28890|Euryarchaeota	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRD1_k127_4905448_5	1385520.N802_09865	1.794e-08	65.0	2CC7D@1|root,33HWJ@2|Bacteria,2IP68@201174|Actinobacteria,4FJ2F@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4905448_0	1386089.N865_11580	4.896e-126	430.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4FJUP@85021|Intrasporangiaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRD1_k127_4905448_2	66429.JOFL01000020_gene5523	6.378e-79	271.0	COG2197@1|root,COG2197@2|Bacteria,2IIDD@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD1_k127_4905448_4	83332.Rv0582	1.62e-08	59.0	COG2402@1|root,COG2402@2|Bacteria,2HZHQ@201174|Actinobacteria,23BTY@1762|Mycobacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
SRD1_k127_4905448_3	1282361.ABAC402_06505	8.21e-14	74.0	COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,2UFM5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Transglycosylase-associated protein	MA20_19350	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRD1_k127_4922377_1	367299.JOEE01000001_gene1898	4.435e-111	365.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4FEEW@85021|Intrasporangiaceae	201174|Actinobacteria	V	Multidrug ABC transporter ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRD1_k127_4922377_0	479431.Namu_0806	7.996e-124	421.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4ERP6@85013|Frankiales	201174|Actinobacteria	V	ABC transporter, transmembrane region	yfiC	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRD1_k127_4940656_1	661478.OP10G_3165	4.313e-10	72.0	28JU0@1|root,2Z9J3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4940656_0	1245469.S58_56860	1.835e-16	80.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,3JRGD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14,4.4.1.23	ko:K00549,ko:K22363	ko00270,ko00450,ko00625,ko01100,ko01110,ko01230,map00270,map00450,map00625,map01100,map01110,map01230	M00017	R04405,R09365,R11897,R11899	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRD1_k127_4941984_10	1429046.RR21198_1694	9.758e-09	59.0	COG1680@1|root,COG1680@2|Bacteria,2GN1H@201174|Actinobacteria,4G8ND@85025|Nocardiaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRD1_k127_4941984_0	1068978.AMETH_3059	3.173e-113	381.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4DZCT@85010|Pseudonocardiales	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,PAP2_3,WES_acyltransf
SRD1_k127_4941984_7	357808.RoseRS_1141	3.034e-20	104.0	COG3467@1|root,COG3467@2|Bacteria,2G77X@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRD1_k127_4941984_6	1304865.JAGF01000001_gene1567	2.925e-23	114.0	COG3871@1|root,COG3871@2|Bacteria	1304865.JAGF01000001_gene1567|-	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4941984_2	1184609.KILIM_005_00510	1.346e-81	279.0	COG1266@1|root,COG1266@2|Bacteria,2IGUR@201174|Actinobacteria	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRD1_k127_4941984_1	1128421.JAGA01000002_gene1189	2.657e-92	312.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4941984_4	1128421.JAGA01000002_gene1188	1.929e-50	192.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRD1_k127_4941984_9	1120950.KB892830_gene5046	1.901e-13	72.0	COG2524@1|root,COG2524@2|Bacteria,2I1DT@201174|Actinobacteria,4DWBB@85009|Propionibacteriales	201174|Actinobacteria	K	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRD1_k127_4941984_5	1385519.N801_05270	9.869e-49	180.0	COG4635@1|root,COG4635@2|Bacteria,2IQCQ@201174|Actinobacteria	201174|Actinobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
SRD1_k127_4941984_8	252305.OB2597_09419	4.053e-14	77.0	COG2905@1|root,COG2905@2|Bacteria,1N7MU@1224|Proteobacteria,2UGVF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG0517 FOG CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRD1_k127_4941984_3	391009.Tmel_0603	1.076e-65	233.0	COG0334@1|root,COG0334@2|Bacteria,2GCH4@200918|Thermotogae	2|Bacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.gdhA	ELFV_dehydrog,ELFV_dehydrog_N
SRD1_k127_4944507_5	698964.CDPW8_1141	8.774e-06	50.0	2DQ2A@1|root,334FV@2|Bacteria,2I1WX@201174|Actinobacteria,22MP3@1653|Corynebacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4944507_4	204669.Acid345_1382	2.099e-07	59.0	2BM3X@1|root,33KY1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4944507_3	1137269.AZWL01000017_gene472	7.233e-11	73.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRD1_k127_4944507_1	1160718.SU9_01020	2.077e-46	181.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria	201174|Actinobacteria	C	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRD1_k127_4944507_2	639282.DEFDS_1576	2.433e-16	85.0	COG0071@1|root,COG0071@2|Bacteria,2GFTF@200930|Deferribacteres	200930|Deferribacteres	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRD1_k127_4944507_0	345341.KUTG_02447	3.941e-204	651.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4E035@85010|Pseudonocardiales	201174|Actinobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRD1_k127_4963967_2	882086.SacxiDRAFT_3806	4.242e-81	274.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4E111@85010|Pseudonocardiales	201174|Actinobacteria	C	xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRD1_k127_4963967_0	1150398.JIBJ01000012_gene2159	2.253e-111	379.0	2DBC4@1|root,2Z8BS@2|Bacteria,2GYBF@201174|Actinobacteria	201174|Actinobacteria	S	Responsible for the hydrolysis of barbituric acid (2,4,6-trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid	bar	-	3.5.2.1,3.5.2.15	ko:K03383,ko:K19794	ko00240,ko00791,ko01100,ko01120,map00240,map00791,map01100,map01120	-	R02139,R05561,R10777	RC00632,RC00680,RC01423,RC03058	ko00000,ko00001,ko01000	-	-	-	Amido_AtzD_TrzD
SRD1_k127_4963967_3	309801.trd_0173	1.501e-53	211.0	COG0154@1|root,COG0154@2|Bacteria,2G7WJ@200795|Chloroflexi,27XWA@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRD1_k127_4963967_6	123899.JPQP01000020_gene2036	3.652e-28	123.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,2VQBX@28216|Betaproteobacteria,3T4EW@506|Alcaligenaceae	28216|Betaproteobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRD1_k127_4963967_5	1189612.A33Q_4394	7.86e-45	178.0	COG1835@1|root,COG1835@2|Bacteria,4NHPE@976|Bacteroidetes,47JWZ@768503|Cytophagia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	ko:K11941	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
SRD1_k127_4963967_8	1122611.KB903981_gene3403	0.0008754	49.0	COG3371@1|root,COG3371@2|Bacteria,2GTR3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRD1_k127_4963967_4	1463887.KL589953_gene25	1.025e-48	182.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria	201174|Actinobacteria	C	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRD1_k127_4963967_1	1120936.KB907217_gene3549	4.983e-111	378.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4EGQJ@85012|Streptosporangiales	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA_3,PAS_4
SRD1_k127_4963967_7	1179773.BN6_01330	4.441e-17	83.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,4E0MG@85010|Pseudonocardiales	201174|Actinobacteria	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD1_k127_4967693_1	316274.Haur_3570	1.404e-62	231.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,2GAB0@200795|Chloroflexi,374U6@32061|Chloroflexia	32061|Chloroflexia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HD
SRD1_k127_4967693_0	1313301.AUGC01000001_gene1488	5.13e-77	267.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRD1_k127_4972239_9	1211035.CD30_03580	2.244e-13	70.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli,3IY4W@400634|Lysinibacillus	91061|Bacilli	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRD1_k127_4972239_10	1298865.H978DRAFT_3962	3.951e-13	71.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,1SGC9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRD1_k127_4972239_11	370438.PTH_0343	4.753e-13	78.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,262EV@186807|Peptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRD1_k127_4972239_1	643648.Slip_2215	1.897e-90	304.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,42JSQ@68298|Syntrophomonadaceae	186801|Clostridia	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRD1_k127_4972239_2	1123373.ATXI01000015_gene1207	2.223e-68	239.0	COG0563@1|root,COG0563@2|Bacteria,2GGXU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRD1_k127_4972239_0	479434.Sthe_1056	7.216e-107	362.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi,27XI1@189775|Thermomicrobia	189775|Thermomicrobia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRD1_k127_4972239_5	1123405.AUMM01000026_gene2205	1.716e-41	160.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,26NW1@186821|Sporolactobacillaceae	91061|Bacilli	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRD1_k127_4972239_12	479434.Sthe_1054	2.666e-11	76.0	COG1841@1|root,COG1841@2|Bacteria,2G7E7@200795|Chloroflexi,27YRK@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRD1_k127_4972239_3	1121472.AQWN01000002_gene2056	1.63e-67	235.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,261HV@186807|Peptococcaceae	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRD1_k127_4972239_7	1120933.ATUY01000011_gene650	1.87e-32	138.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4D5ZC@85005|Actinomycetales	201174|Actinobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRD1_k127_4972239_4	696281.Desru_0313	1.198e-63	227.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,261NE@186807|Peptococcaceae	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRD1_k127_4972239_6	105420.BBPO01000022_gene5789	1.733e-40	157.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,2NIAQ@228398|Streptacidiphilus	201174|Actinobacteria	J	Ribosomal protein S8	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRD1_k127_4972239_8	944479.JQLX01000017_gene299	5.606e-23	98.0	COG0199@1|root,COG0199@2|Bacteria,1PDMJ@1224|Proteobacteria,42VCE@68525|delta/epsilon subdivisions,2WR7W@28221|Deltaproteobacteria,2M7GG@213113|Desulfurellales	28221|Deltaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRD1_k127_4976373_3	886293.Sinac_5592	9.286e-16	87.0	COG0210@1|root,COG0210@2|Bacteria,2IWTI@203682|Planctomycetes	203682|Planctomycetes	L	COG0210 Superfamily I DNA and RNA	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRD1_k127_4976373_4	1123389.ATXJ01000001_gene716	2.341e-08	59.0	COG5512@1|root,COG5512@2|Bacteria,1WIYS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRD1_k127_4976373_2	1120973.AQXL01000114_gene716	3.549e-67	242.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,277VW@186823|Alicyclobacillaceae	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRD1_k127_4976373_1	311424.DhcVS_1009	4.512e-83	289.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi,34CUN@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRD1_k127_4976373_0	1031288.AXAA01000049_gene2128	7.158e-94	313.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,36DSQ@31979|Clostridiaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRD1_k127_4995750_3	1121378.KB899702_gene2272	1.713e-08	66.0	COG1404@1|root,COG1404@2|Bacteria,1WKW6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	S53, subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRD1_k127_4995750_1	749414.SBI_05879	5.793e-51	189.0	COG2197@1|root,COG2197@2|Bacteria,2I126@201174|Actinobacteria	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD1_k127_4995750_0	1382359.JIAL01000001_gene2050	1.17e-54	206.0	2DBVK@1|root,2ZBBH@2|Bacteria,3Y3II@57723|Acidobacteria,2JJ0E@204432|Acidobacteriia	204432|Acidobacteriia	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRD1_k127_4995750_2	1451261.AS96_00190	4.277e-17	86.0	COG4420@1|root,COG4420@2|Bacteria,2IHZA@201174|Actinobacteria,4FT5C@85023|Microbacteriaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4997503_3	1128421.JAGA01000003_gene2774	6.114e-23	105.0	2E3S2@1|root,32YPN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_4997503_0	525904.Tter_2605	2.973e-52	199.0	COG1472@1|root,COG1472@2|Bacteria,2NNZB@2323|unclassified Bacteria	2|Bacteria	G	Glycoside hydrolase family 3 domain protein	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
SRD1_k127_4997503_2	684949.ATTJ01000003_gene3233	9.399e-27	121.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRD1_k127_4997503_1	234621.RER_10530	5.019e-31	126.0	COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria,4G094@85025|Nocardiaceae	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRD1_k127_5005230_9	292459.STH634	1.572e-16	89.0	COG0400@1|root,COG0400@2|Bacteria,1V5GR@1239|Firmicutes,24S3Z@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5005230_0	1313172.YM304_13880	5.38e-167	540.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4CNIJ@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
SRD1_k127_5005230_7	574087.Acear_1890	2.245e-21	111.0	COG5662@1|root,COG5662@2|Bacteria,1UHWV@1239|Firmicutes,24JF8@186801|Clostridia,3WBR9@53433|Halanaerobiales	186801|Clostridia	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
SRD1_k127_5005230_5	345341.KUTG_02226	2.878e-29	123.0	COG1595@1|root,COG1595@2|Bacteria,2IG1M@201174|Actinobacteria,4E9SD@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRD1_k127_5005230_8	1206744.BAGL01000059_gene1865	5.028e-17	93.0	COG2146@1|root,COG2146@2|Bacteria,2I9FW@201174|Actinobacteria,4G11N@85025|Nocardiaceae	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRD1_k127_5005230_1	1118054.CAGW01000083_gene2864	6.754e-164	525.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,26QFD@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRD1_k127_5005230_2	357808.RoseRS_3331	3.598e-96	331.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi,3759H@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.3.1.13	ko:K15526	-	-	-	-	ko00000,ko01000	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRD1_k127_5005230_3	479434.Sthe_3364	7.322e-73	271.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi,27Z1H@189775|Thermomicrobia	189775|Thermomicrobia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRD1_k127_5005230_4	479434.Sthe_3365	5.18e-70	251.0	COG1131@1|root,COG1131@2|Bacteria,2G6JW@200795|Chloroflexi,27YZ8@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_5005230_6	345341.KUTG_02291	1.293e-25	111.0	COG1309@1|root,COG1309@2|Bacteria,2HXVA@201174|Actinobacteria,4E41W@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD1_k127_5032353_2	1283283.ATXA01000041_gene2245	6.788e-29	126.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4EUCJ@85013|Frankiales	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD1_k127_5032353_0	1123288.SOV_2c11860	1.79e-67	243.0	COG0745@1|root,COG0745@2|Bacteria,1U3FH@1239|Firmicutes,4H3RA@909932|Negativicutes	909932|Negativicutes	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_5032353_1	324602.Caur_0875	4.851e-34	148.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRD1_k127_5041940_1	671143.DAMO_3011	1.755e-136	444.0	COG1459@1|root,COG1459@2|Bacteria,2NP2J@2323|unclassified Bacteria	2|Bacteria	U	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
SRD1_k127_5041940_2	671143.DAMO_3010	5.433e-85	302.0	COG5000@1|root,COG5000@2|Bacteria,2NP6K@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
SRD1_k127_5041940_0	1232410.KI421416_gene2592	2.058e-156	513.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43UCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRD1_k127_5044138_0	1123023.JIAI01000004_gene7828	1.324e-210	660.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2GJCK@201174|Actinobacteria,4DZEM@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRD1_k127_5044138_8	1123023.JIAI01000004_gene7829	4.414e-55	217.0	COG3058@1|root,COG3058@2|Bacteria	2|Bacteria	O	ferric iron binding	fdhE	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008199,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0051604,GO:0055114,GO:0071704,GO:1901564	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
SRD1_k127_5044138_2	1123023.JIAI01000004_gene7830	2.595e-132	427.0	COG0437@1|root,COG0437@2|Bacteria,2I2DV@201174|Actinobacteria,4E0GZ@85010|Pseudonocardiales	201174|Actinobacteria	C	formate dehydrogenase, beta subunit	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3,Fer4_7
SRD1_k127_5044138_11	479434.Sthe_2477	2.061e-15	90.0	COG3301@1|root,COG3301@2|Bacteria,2G8A3@200795|Chloroflexi,27XFI@189775|Thermomicrobia	189775|Thermomicrobia	P	Polysulfide reductase	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
SRD1_k127_5044138_4	479434.Sthe_0642	2.343e-108	362.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi,27XJW@189775|Thermomicrobia	189775|Thermomicrobia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRD1_k127_5044138_1	1133850.SHJG_8634	7.853e-208	662.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria	201174|Actinobacteria	E	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRD1_k127_5044138_7	479434.Sthe_1511	2.627e-70	261.0	COG1173@1|root,COG1173@2|Bacteria,2G841@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRD1_k127_5044138_5	479434.Sthe_0679	8.354e-108	357.0	COG0601@1|root,COG0601@2|Bacteria,2G6BV@200795|Chloroflexi,27XFE@189775|Thermomicrobia	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRD1_k127_5044138_3	485913.Krac_3079	3.427e-126	422.0	COG0747@1|root,COG0747@2|Bacteria,2G6BC@200795|Chloroflexi	200795|Chloroflexi	E	COGs COG0747 ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD1_k127_5044138_10	1297742.A176_01679	9.402e-31	128.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,42TBH@68525|delta/epsilon subdivisions,2WPJ5@28221|Deltaproteobacteria,2YW2S@29|Myxococcales	28221|Deltaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRD1_k127_5044138_6	479433.Caci_4804	1.029e-71	250.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRD1_k127_5044138_9	380703.AHA_3405	2.967e-40	154.0	COG2313@1|root,COG2313@2|Bacteria,1MUQU@1224|Proteobacteria,1RQJH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	GO:0001522,GO:0003674,GO:0003824,GO:0004730,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016043,GO:0016070,GO:0016787,GO:0016798,GO:0016829,GO:0016835,GO:0016836,GO:0022607,GO:0030145,GO:0034641,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0090304,GO:1901360	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
SRD1_k127_5047945_0	1356852.N008_00900	8.489e-158	508.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,47KBI@768503|Cytophagia	976|Bacteroidetes	C	Dehydrogenase E1 component	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRD1_k127_5047945_1	457570.Nther_1744	8.39e-87	308.0	COG0616@1|root,COG0616@2|Bacteria,1V7VW@1239|Firmicutes,24ME2@186801|Clostridia	186801|Clostridia	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRD1_k127_5092725_2	1123504.JQKD01000076_gene5816	1.466e-14	76.0	COG4177@1|root,COG4177@2|Bacteria,1P0DF@1224|Proteobacteria,2VKP9@28216|Betaproteobacteria,4ADF3@80864|Comamonadaceae	28216|Betaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD1_k127_5092725_0	1120936.KB907208_gene1216	3.102e-91	308.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria,4EIQD@85012|Streptosporangiales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD1_k127_5092725_1	1121106.JQKB01000020_gene1996	3.86e-73	251.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2U1BU@28211|Alphaproteobacteria,2JW92@204441|Rhodospirillales	204441|Rhodospirillales	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRD1_k127_5103685_1	479434.Sthe_2307	2.977e-45	181.0	COG2203@1|root,COG2508@1|root,COG3170@1|root,COG2203@2|Bacteria,COG2508@2|Bacteria,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	2.7.11.1,3.5.1.104	ko:K03699,ko:K12132,ko:K17763,ko:K22278	-	-	-	-	ko00000,ko01000,ko01001,ko02042,ko03021	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,GAF,GAF_2,HTH_30
SRD1_k127_5103685_0	1521187.JPIM01000017_gene353	5.897e-106	358.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2G5VK@200795|Chloroflexi,37589@32061|Chloroflexia	32061|Chloroflexia	E	glutamate synthase, alpha subunit domain protein	-	-	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRD1_k127_511207_3	574087.Acear_0299	2.046e-43	174.0	COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,247KD@186801|Clostridia,3WC1G@53433|Halanaerobiales	186801|Clostridia	F	Adenosine/AMP deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS13960	A_deaminase
SRD1_k127_511207_2	589865.DaAHT2_2560	2.841e-46	173.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,42SNI@68525|delta/epsilon subdivisions,2WPFN@28221|Deltaproteobacteria,2MKAJ@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRD1_k127_511207_1	58123.JOFJ01000004_gene1873	1.496e-89	303.0	COG1012@1|root,COG1012@2|Bacteria,2GKSN@201174|Actinobacteria,4EHBQ@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD1_k127_511207_0	479432.Sros_0778	3.61e-226	706.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4EH5D@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD1_k127_5120961_2	240015.ACP_0214	1.123e-70	249.0	COG0389@1|root,COG0389@2|Bacteria,3Y3NY@57723|Acidobacteria,2JIP4@204432|Acidobacteriia	204432|Acidobacteriia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRD1_k127_5120961_1	1340493.JNIF01000004_gene171	3.652e-76	262.0	COG1209@1|root,COG1209@2|Bacteria,3Y2ZJ@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRD1_k127_5120961_3	1047013.AQSP01000144_gene832	2.884e-38	151.0	COG1898@1|root,COG1898@2|Bacteria,2NPIP@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRD1_k127_5120961_0	357808.RoseRS_1611	7.194e-124	406.0	COG1088@1|root,COG1088@2|Bacteria,2G5KR@200795|Chloroflexi,375GP@32061|Chloroflexia	32061|Chloroflexia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRD1_k127_5141394_2	1382306.JNIM01000001_gene1168	2.293e-116	379.0	COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi	200795|Chloroflexi	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRD1_k127_5141394_4	243274.THEMA_07405	1.181e-54	196.0	COG0503@1|root,COG0503@2|Bacteria,2GCSE@200918|Thermotogae	200918|Thermotogae	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRD1_k127_5141394_1	237368.SCABRO_00387	6.285e-123	401.0	COG0451@1|root,COG0451@2|Bacteria,2IWW0@203682|Planctomycetes	203682|Planctomycetes	GM	NAD- dependent epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRD1_k127_5141394_0	1382306.JNIM01000001_gene3879	9.107e-156	520.0	COG1004@1|root,COG1004@2|Bacteria,2G62F@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRD1_k127_5141394_5	644282.Deba_0451	4.027e-46	187.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,43AVJ@68525|delta/epsilon subdivisions,2X69P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD1_k127_5141394_3	575540.Isop_0086	2.835e-70	244.0	COG0677@1|root,COG0677@2|Bacteria,2IXVX@203682|Planctomycetes	2|Bacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wecC	-	1.1.1.132,1.1.1.136,1.1.1.336	ko:K00066,ko:K02472,ko:K02474,ko:K13015	ko00051,ko00520,ko02020,ko05111,map00051,map00520,map02020,map05111	-	R00421,R00880,R03317,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRD1_k127_5142878_2	944480.ATUV01000001_gene864	6.308e-14	79.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,42QGR@68525|delta/epsilon subdivisions,2WKUQ@28221|Deltaproteobacteria,2M72K@213113|Desulfurellales	28221|Deltaproteobacteria	S	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SRD1_k127_5142878_1	439235.Dalk_0059	2.494e-44	178.0	COG1024@1|root,COG1024@2|Bacteria,1R56Y@1224|Proteobacteria,42MRW@68525|delta/epsilon subdivisions,2WKNI@28221|Deltaproteobacteria,2MJAI@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD1_k127_5142878_0	1234664.AMRO01000022_gene1652	7.006e-76	257.0	COG1028@1|root,COG1028@2|Bacteria,1V14I@1239|Firmicutes,4HCT7@91061|Bacilli,1WFZ8@129337|Geobacillus	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRD1_k127_5152875_1	485913.Krac_7256	3.915e-91	305.0	COG0667@1|root,COG0667@2|Bacteria,2G5N6@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRD1_k127_5152875_0	351607.Acel_1822	2.916e-151	493.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4ES4Q@85013|Frankiales	201174|Actinobacteria	G	PFAM Glycosyl transferase, group 1	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRD1_k127_5152875_3	1343740.M271_36785	6.899e-24	112.0	COG3878@1|root,COG3878@2|Bacteria,2IB6Q@201174|Actinobacteria	201174|Actinobacteria	C	Domain of unknown function (DUF1963)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1963
SRD1_k127_5152875_2	479432.Sros_9382	2.734e-88	305.0	COG0596@1|root,COG0596@2|Bacteria,2I97G@201174|Actinobacteria,4EPC0@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRD1_k127_5152875_4	292459.STH2103	2.769e-19	93.0	COG3714@1|root,COG3714@2|Bacteria,1VD4D@1239|Firmicutes	1239|Firmicutes	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
SRD1_k127_5155431_2	1122218.KB893653_gene1138	4.607e-12	66.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2TR5M@28211|Alphaproteobacteria,1JQVS@119045|Methylobacteriaceae	28211|Alphaproteobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRD1_k127_5155431_1	211114.JOEF01000009_gene1697	2.777e-87	301.0	COG0451@1|root,COG0451@2|Bacteria,2HQWK@201174|Actinobacteria,4E9XH@85010|Pseudonocardiales	201174|Actinobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5155431_0	118163.Ple7327_0392	2.066e-185	609.0	COG1615@1|root,COG1615@2|Bacteria,1G05D@1117|Cyanobacteria,3VIF0@52604|Pleurocapsales	1117|Cyanobacteria	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRD1_k127_5166207_5	889378.Spiaf_1207	1.576e-46	185.0	COG1196@1|root,COG1196@2|Bacteria,2J57J@203691|Spirochaetes	203691|Spirochaetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N
SRD1_k127_5166207_3	1378168.N510_01556	4.871e-66	238.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes	1239|Firmicutes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRD1_k127_5166207_11	572479.Hprae_1828	2.062e-15	87.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,3WBCP@53433|Halanaerobiales	186801|Clostridia	S	PFAM PHP domain	trpH	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
SRD1_k127_5166207_4	349124.Hhal_1796	2e-56	208.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1WWE2@135613|Chromatiales	135613|Chromatiales	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRD1_k127_5166207_8	1380390.JIAT01000009_gene704	5.362e-28	120.0	COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria,4CQQR@84995|Rubrobacteria	84995|Rubrobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRD1_k127_5166207_9	485913.Krac_5508	2.69e-26	113.0	COG2318@1|root,COG2318@2|Bacteria,2G92D@200795|Chloroflexi	2|Bacteria	S	SPTR D1C1B9 DinB family protein	dinB	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB
SRD1_k127_5166207_12	1111479.AXAR01000004_gene2041	7.882e-13	76.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli	91061|Bacilli	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	ylxM	GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
SRD1_k127_5166207_0	665956.HMPREF1032_00081	1.837e-121	403.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3WH5J@541000|Ruminococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRD1_k127_5166207_7	997346.HMPREF9374_0881	3.631e-28	123.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,27C4Q@186824|Thermoactinomycetaceae	91061|Bacilli	J	Ribosomal protein S16	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRD1_k127_5166207_13	1121918.ARWE01000001_gene845	2.544e-11	70.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,43SP5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	KH domain	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRD1_k127_5166207_10	908339.HMPREF9265_0686	2.641e-23	108.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,3F74P@33958|Lactobacillaceae	91061|Bacilli	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRD1_k127_5166207_1	1382306.JNIM01000001_gene4081	3.568e-72	249.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRD1_k127_5166207_6	871968.DESME_11550	7.915e-39	154.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,261ZW@186807|Peptococcaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRD1_k127_5166207_2	1144275.COCOR_06731	3.392e-70	249.0	COG0438@1|root,COG0438@2|Bacteria,1MYTB@1224|Proteobacteria,42MCA@68525|delta/epsilon subdivisions,2WJVX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
SRD1_k127_5169100_6	1355368.JART01000002_gene2262	3.273e-07	61.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2YMSC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
SRD1_k127_5169100_0	1131269.AQVV01000025_gene2340	2.253e-62	224.0	COG0377@1|root,COG0377@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRD1_k127_5169100_2	671143.DAMO_2700	5.93e-33	134.0	COG0838@1|root,COG0838@2|Bacteria,2NPTW@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRD1_k127_5169100_4	1345697.M493_09125	3.025e-20	96.0	COG1765@1|root,COG1765@2|Bacteria,1V7SN@1239|Firmicutes,4HIEM@91061|Bacilli,1WFEG@129337|Geobacillus	91061|Bacilli	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
SRD1_k127_5169100_5	404589.Anae109_3547	3.299e-14	85.0	COG0457@1|root,COG0457@2|Bacteria	404589.Anae109_3547|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5169100_3	929712.KI912613_gene2851	4.687e-23	111.0	COG0457@1|root,COG0457@2|Bacteria	929712.KI912613_gene2851|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5169100_1	986075.CathTA2_1076	6.646e-37	155.0	COG0500@1|root,COG2226@2|Bacteria,1UZN6@1239|Firmicutes,4HB38@91061|Bacilli	91061|Bacilli	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRD1_k127_5193366_3	479433.Caci_8762	2.402e-24	119.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD16	-	6.2.1.41	ko:K18687	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R10769	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRD1_k127_5193366_0	28444.JODQ01000006_gene195	8.941e-144	472.0	COG2986@1|root,COG2986@2|Bacteria,2GJZW@201174|Actinobacteria,4EFM8@85012|Streptosporangiales	201174|Actinobacteria	E	Aromatic amino acid lyase	-	-	4.3.1.24,4.3.1.3,5.4.3.6	ko:K01745,ko:K10775,ko:K21181	ko00340,ko00360,ko00940,ko01059,ko01100,ko01110,ko01130,map00340,map00360,map00940,map01059,map01100,map01110,map01130	M00039,M00045,M00137,M00350,M00827,M00828	R00697,R01168,R11366	RC00361,RC00366	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRD1_k127_5193366_2	189753.AXAS01000075_gene6003	6.487e-33	140.0	COG0715@1|root,COG0715@2|Bacteria,1R8AT@1224|Proteobacteria,2U2Z7@28211|Alphaproteobacteria,3K3AI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5193366_1	405948.SACE_3132	5.464e-79	270.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria,4E2EI@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA5	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRD1_k127_5202849_1	204669.Acid345_3437	1.175e-67	242.0	COG2220@1|root,COG2220@2|Bacteria,3Y4RK@57723|Acidobacteria,2JM7M@204432|Acidobacteriia	204432|Acidobacteriia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRD1_k127_5202849_0	469383.Cwoe_2120	1.88e-106	360.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4CPJR@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRD1_k127_5202849_2	309801.trd_A0506	8.925e-25	108.0	COG4867@1|root,COG4867@2|Bacteria,2G8A6@200795|Chloroflexi,27XPF@189775|Thermomicrobia	189775|Thermomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5210066_1	517418.Ctha_1405	5.817e-30	131.0	COG4591@1|root,COG4591@2|Bacteria,1FECJ@1090|Chlorobi	1090|Chlorobi	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRD1_k127_5210066_4	1121924.ATWH01000001_gene4299	5.719e-10	73.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
SRD1_k127_5210066_2	1170562.Cal6303_1282	5.942e-28	122.0	COG0204@1|root,COG0204@2|Bacteria,1G1AK@1117|Cyanobacteria,1HMFN@1161|Nostocales	1117|Cyanobacteria	I	PFAM Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRD1_k127_5210066_3	1382306.JNIM01000001_gene3477	5.512e-14	79.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	rlpA	-	3.5.1.104	ko:K03642,ko:K03791,ko:K22278	-	-	-	-	ko00000,ko01000	-	GH19	-	3D,DPBB_1,Hydrolase_2,LysM
SRD1_k127_5210066_0	1254432.SCE1572_41035	6.478e-35	139.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,42SUQ@68525|delta/epsilon subdivisions,2WPIY@28221|Deltaproteobacteria,2Z0N9@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
SRD1_k127_5210301_4	575540.Isop_2345	5.766e-13	71.0	COG0160@1|root,COG0160@2|Bacteria,2IYBU@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_5210301_3	1121938.AUDY01000008_gene2026	9.187e-14	82.0	28HWT@1|root,2Z82P@2|Bacteria,1TSBJ@1239|Firmicutes,4HCMR@91061|Bacilli,3NFYI@45667|Halobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Xpo1
SRD1_k127_5210301_0	1463856.JOHY01000008_gene945	3.196e-71	250.0	COG0258@1|root,COG0258@2|Bacteria,2GKTZ@201174|Actinobacteria	201174|Actinobacteria	L	5'-3' exonuclease	polA_1	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRD1_k127_5210301_6	469383.Cwoe_2923	9.947e-09	58.0	2A5VU@1|root,30UMP@2|Bacteria,2HRRK@201174|Actinobacteria,4CTU7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5210301_2	1128421.JAGA01000002_gene1044	5.058e-39	152.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_5210301_1	1382306.JNIM01000001_gene1969	2.667e-61	220.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	ogt	-	2.1.1.63,3.2.2.21	ko:K00567,ko:K13529,ko:K15051	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AraC_binding,DNA_binding_1,Endonuclea_NS_2,HTH_18
SRD1_k127_5210301_5	1157637.KB892093_gene6698	1.101e-09	68.0	COG0639@1|root,COG0639@2|Bacteria,2GITY@201174|Actinobacteria	201174|Actinobacteria	T	Serine Threonine protein	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRD1_k127_5214916_0	1054860.KB913030_gene6404	7.344e-46	170.0	COG5646@1|root,COG5646@2|Bacteria,2IINN@201174|Actinobacteria	201174|Actinobacteria	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRD1_k127_5214916_4	1448860.BBJO01000014_gene1283	8.761e-05	51.0	arCOG10130@1|root,arCOG10130@2157|Archaea,2XZWX@28890|Euryarchaeota,23Y13@183963|Halobacteria	183963|Halobacteria	S	metal-sulfur cluster biosynthetic enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5214916_1	1382306.JNIM01000001_gene267	1.998e-33	139.0	COG3396@1|root,COG3396@2|Bacteria,2G9KQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phenylacetic acid catabolic family protein	-	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRD1_k127_5214916_3	1111479.AXAR01000003_gene1557	6.266e-07	59.0	2DTNH@1|root,33M2H@2|Bacteria,1W1AW@1239|Firmicutes,4HZ7K@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5214916_2	1382306.JNIM01000001_gene265	5.272e-32	128.0	COG2151@1|root,COG2151@2|Bacteria,2G9PR@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRD1_k127_5233674_1	1128427.KB904821_gene205	1.147e-167	542.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRD1_k127_5233674_7	1172188.KB911820_gene2790	1.317e-34	138.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,4FGGF@85021|Intrasporangiaceae	201174|Actinobacteria	K	PadR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRD1_k127_5233674_5	1206733.BAGC01000041_gene1871	1.52e-55	203.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4G0D9@85025|Nocardiaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_5233674_3	105422.BBPM01000088_gene7448	1.093e-96	348.0	COG0577@1|root,COG0577@2|Bacteria,2GN4X@201174|Actinobacteria,2NI18@228398|Streptacidiphilus	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRD1_k127_5233674_6	33876.JNXY01000029_gene2663	1.827e-45	173.0	COG1309@1|root,COG1309@2|Bacteria,2HWQ4@201174|Actinobacteria,4DJWP@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD1_k127_5233674_2	1382306.JNIM01000001_gene464	1.477e-105	352.0	COG1131@1|root,COG1131@2|Bacteria,2G5QI@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_5233674_0	485913.Krac_10031	1.073e-193	619.0	COG3559@1|root,COG3559@2|Bacteria,2G7I8@200795|Chloroflexi	200795|Chloroflexi	M	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRD1_k127_5233674_4	1125971.ASJB01000065_gene6268	1.421e-74	260.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRD1_k127_5238137_1	1382306.JNIM01000001_gene4159	6.197e-134	442.0	COG0114@1|root,COG0114@2|Bacteria,2GBNI@200795|Chloroflexi	200795|Chloroflexi	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRD1_k127_5238137_4	1382306.JNIM01000001_gene592	2.096e-32	138.0	COG0248@1|root,COG0248@2|Bacteria,2G776@200795|Chloroflexi	200795|Chloroflexi	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	CHAD,HD,Ppx-GppA
SRD1_k127_5238137_3	1382306.JNIM01000001_gene2027	6.738e-71	250.0	COG1230@1|root,COG1230@2|Bacteria,2G6FI@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRD1_k127_5238137_0	479434.Sthe_0589	1.977e-170	552.0	COG0664@1|root,COG0664@2|Bacteria,2G63K@200795|Chloroflexi,27YV2@189775|Thermomicrobia	189775|Thermomicrobia	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5238137_5	1120972.AUMH01000033_gene3059	0.0001455	52.0	2DZXU@1|root,32VMR@2|Bacteria,1VBBV@1239|Firmicutes,4HPWN@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5238137_2	1191523.MROS_0175	7.121e-108	362.0	COG1022@1|root,COG1022@2|Bacteria	2|Bacteria	I	Amp-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRD1_k127_5250081_1	1476583.DEIPH_ctg046orf0076	8.034e-29	130.0	COG5001@1|root,COG5001@2|Bacteria,1WK20@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS_4,PAS_9
SRD1_k127_5250081_0	138119.DSY3705	3.159e-40	158.0	COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,24FRV@186801|Clostridia,261K2@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRD1_k127_5250081_2	1499967.BAYZ01000137_gene102	1.468e-16	83.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	MA20_40115	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD1_k127_5286208_2	107636.JQNK01000008_gene4141	2.76e-22	106.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRD1_k127_5286208_4	1246626.BleG1_3538	9.36e-12	73.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HCCV@91061|Bacilli,1ZDBY@1386|Bacillus	91061|Bacilli	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	yhcZ	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRD1_k127_5286208_1	95619.PM1_0213980	1.265e-104	358.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRD1_k127_5286208_3	926564.KI911697_gene273	2.986e-17	85.0	COG2350@1|root,COG2350@2|Bacteria,2GV9T@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRD1_k127_5286208_0	1304275.C41B8_09941	4.829e-118	387.0	COG0687@1|root,COG0687@2|Bacteria,1NKD7@1224|Proteobacteria,1RQPF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Spermidine putrescine ABC transporter substrate-binding protein	ydcS	GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	iECNA114_1301.ECNA114_1576,iECSF_1327.ECSF_1364,iEcHS_1320.EcHS_A1524	SBP_bac_8
SRD1_k127_5306602_2	469371.Tbis_1049	1.048e-42	160.0	COG1611@1|root,COG1611@2|Bacteria,2IN1B@201174|Actinobacteria,4E5V0@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRD1_k127_5306602_0	525904.Tter_0555	8.717e-107	354.0	COG1085@1|root,COG1085@2|Bacteria,2NQV8@2323|unclassified Bacteria	2|Bacteria	C	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
SRD1_k127_5306602_1	765420.OSCT_2566	3.193e-51	195.0	COG0153@1|root,COG0153@2|Bacteria,2G6CE@200795|Chloroflexi,375CJ@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRD1_k127_5338286_2	638302.HMPREF0908_1784	1.041e-35	145.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,4H26Q@909932|Negativicutes	909932|Negativicutes	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRD1_k127_5338286_0	373903.Hore_09190	5.483e-50	181.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3WBUJ@53433|Halanaerobiales	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRD1_k127_5338286_1	871968.DESME_12310	1.512e-42	160.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,260UE@186807|Peptococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRD1_k127_5344971_0	324602.Caur_0354	1.889e-56	203.0	COG1351@1|root,COG1351@2|Bacteria,2G8EZ@200795|Chloroflexi,374YN@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRD1_k127_5344971_2	525904.Tter_1481	4.053e-27	122.0	COG2265@1|root,COG2265@2|Bacteria,2NRDB@2323|unclassified Bacteria	2|Bacteria	J	Methyltransferase domain	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Methyltransf_21,Methyltransf_25,Methyltransf_31
SRD1_k127_5344971_3	523850.TON_1158	1.122e-13	83.0	COG0454@1|root,arCOG00845@2157|Archaea,2Y67B@28890|Euryarchaeota,2430F@183968|Thermococci	183968|Thermococci	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD1_k127_5344971_1	525904.Tter_0858	7.638e-34	133.0	COG1251@1|root,COG1251@2|Bacteria,2NS41@2323|unclassified Bacteria	2|Bacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	narC	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
SRD1_k127_5366027_0	1123023.JIAI01000004_gene7828	6.699e-225	704.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2GJCK@201174|Actinobacteria,4DZEM@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRD1_k127_5366027_1	1123023.JIAI01000004_gene7827	1.676e-82	284.0	COG0243@1|root,COG0243@2|Bacteria,2GJ7X@201174|Actinobacteria,4E328@85010|Pseudonocardiales	201174|Actinobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4
SRD1_k127_5366027_2	1123023.JIAI01000004_gene7826	8.232e-10	67.0	2B2YI@1|root,31VJH@2|Bacteria,2GVT3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5366027_3	1187851.A33M_2348	9.289e-10	61.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,3FDFW@34008|Rhodovulum	28211|Alphaproteobacteria	J	Phosphoglucose isomerase	tal	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
SRD1_k127_5366454_2	1121440.AUMA01000021_gene219	1.828e-52	190.0	COG2164@1|root,COG2164@2|Bacteria,1RCY5@1224|Proteobacteria,431Q6@68525|delta/epsilon subdivisions,2WWUX@28221|Deltaproteobacteria,2MFA6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3830)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3830
SRD1_k127_5366454_1	1120948.KB903217_gene1337	1.363e-131	447.0	COG1457@1|root,COG1457@2|Bacteria,2GJ6B@201174|Actinobacteria,4EEQH@85010|Pseudonocardiales	201174|Actinobacteria	U	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
SRD1_k127_5366454_0	1122223.KB890688_gene1630	5.226e-146	476.0	COG0402@1|root,COG0402@2|Bacteria	2|Bacteria	F	S-adenosylhomocysteine deaminase activity	codA	GO:0003674,GO:0003824,GO:0004131,GO:0005488,GO:0005506,GO:0005515,GO:0006139,GO:0006206,GO:0006208,GO:0006209,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0019439,GO:0019858,GO:0034641,GO:0035888,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.4.1,3.5.4.21	ko:K01485,ko:K03365	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_0343,iEcSMS35_1347.EcSMS35_0368	Amidohydro_3
SRD1_k127_5366454_3	517417.Cpar_1613	6.295e-47	175.0	COG0634@1|root,COG0634@2|Bacteria,1FE2X@1090|Chlorobi	1090|Chlorobi	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRD1_k127_5366454_5	1227497.C491_14577	1.283e-33	138.0	COG3369@1|root,arCOG03175@1|root,arCOG03174@2157|Archaea,arCOG03175@2157|Archaea,2Y1YC@28890|Euryarchaeota,23ZKU@183963|Halobacteria	183963|Halobacteria	S	CDGSH-type zinc finger. Function unknown.	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
SRD1_k127_5366454_4	326424.FRAAL2583	1.269e-33	139.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRD1_k127_5366454_6	269796.Rru_A2788	2.394e-19	91.0	COG0402@1|root,COG0402@2|Bacteria,1MX34@1224|Proteobacteria,2U0IN@28211|Alphaproteobacteria,2JR86@204441|Rhodospirillales	204441|Rhodospirillales	F	Amidohydrolase family	-	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_3
SRD1_k127_5372016_1	644966.Tmar_0169	2.821e-200	642.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3WCCD@538999|Clostridiales incertae sedis	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRD1_k127_5372016_2	525904.Tter_0064	3.515e-76	264.0	COG0224@1|root,COG0224@2|Bacteria,2NP76@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138	ATP-synt
SRD1_k127_5372016_0	525904.Tter_0065	2.875e-214	676.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRD1_k127_5372016_4	1033802.SSPSH_002238	2.434e-24	109.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953	OSCP
SRD1_k127_5372016_6	1123024.AUII01000016_gene1320	7.542e-13	78.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4E5ST@85010|Pseudonocardiales	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iNJ661.Rv1306	ATP-synt_B
SRD1_k127_5372016_5	47839.CCAU010000013_gene4995	1.692e-13	72.0	COG0636@1|root,COG0636@2|Bacteria,2IQZQ@201174|Actinobacteria,23AQH@1762|Mycobacteriaceae	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0015988,GO:0015991,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iNJ661.Rv1305	ATP-synt_C
SRD1_k127_5372016_3	1298863.AUEP01000001_gene894	5.387e-40	162.0	COG0356@1|root,COG0356@2|Bacteria,2HY9H@201174|Actinobacteria,4DTV7@85009|Propionibacteriales	201174|Actinobacteria	C	ATP synthase A chain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_A
SRD1_k127_5372016_7	265729.GS18_0216860	5.057e-05	48.0	COG5336@1|root,COG5336@2|Bacteria,1VF5M@1239|Firmicutes,4HNYV@91061|Bacilli,1ZJ1K@1386|Bacillus	91061|Bacilli	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
SRD1_k127_5407003_1	926554.KI912673_gene2864	4.792e-22	108.0	COG0697@1|root,COG0697@2|Bacteria,1WJM1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRD1_k127_5407003_0	247490.KSU1_D1051	8.044e-156	504.0	COG2317@1|root,COG2317@2|Bacteria,2IXSU@203682|Planctomycetes	203682|Planctomycetes	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
SRD1_k127_5412383_2	309801.trd_0829	4.846e-42	156.0	COG0292@1|root,COG0292@2|Bacteria,2G6V4@200795|Chloroflexi,27YHE@189775|Thermomicrobia	189775|Thermomicrobia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRD1_k127_5412383_3	742738.HMPREF9460_02751	4.101e-31	133.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,268GU@186813|unclassified Clostridiales	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SRD1_k127_5412383_1	264732.Moth_1751	1.3e-102	354.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,42EPG@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRD1_k127_5412383_0	555079.Toce_1396	4.83e-164	550.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,42F4K@68295|Thermoanaerobacterales	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
SRD1_k127_5416095_1	471852.Tcur_3618	6.299e-230	744.0	COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria,4EFM1@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRD1_k127_5416095_2	1283299.AUKG01000001_gene2498	3.708e-180	577.0	COG2986@1|root,COG2986@2|Bacteria,2GJZW@201174|Actinobacteria,4CPAC@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM phenylalanine histidine ammonia-lyase	-	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRD1_k127_5416095_5	298655.KI912266_gene277	3.242e-59	223.0	COG4912@1|root,COG4912@2|Bacteria,2GNQD@201174|Actinobacteria,4EWG8@85013|Frankiales	201174|Actinobacteria	L	DNA alkylation repair enzyme	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRD1_k127_5416095_7	1313172.YM304_09680	7.563e-17	93.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	3.6.1.55	ko:K03574,ko:K08296	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRD1_k127_5416095_3	345341.KUTG_00490	4.366e-103	352.0	COG5607@1|root,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria,4EAUR@85010|Pseudonocardiales	201174|Actinobacteria	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
SRD1_k127_5416095_0	477641.MODMU_4459	2.812e-231	736.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4ERTG@85013|Frankiales	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRD1_k127_5416095_6	634177.GLX_04430	1.401e-37	153.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2TQS4@28211|Alphaproteobacteria,2JQ1E@204441|Rhodospirillales	204441|Rhodospirillales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRD1_k127_5416095_4	1121926.AXWO01000018_gene2469	2.498e-96	328.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4EY3H@85014|Glycomycetales	201174|Actinobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRD1_k127_5418518_0	383372.Rcas_1932	1.321e-73	259.0	COG2723@1|root,COG2723@2|Bacteria,2G5QE@200795|Chloroflexi,3774T@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRD1_k127_5418518_3	479434.Sthe_1418	1.569e-19	94.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi,27YDN@189775|Thermomicrobia	189775|Thermomicrobia	CO	Thioredoxin-like	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
SRD1_k127_5418518_2	525904.Tter_1506	1.26e-22	105.0	COG2332@1|root,COG2332@2|Bacteria,2NQ2A@2323|unclassified Bacteria	2|Bacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
SRD1_k127_5418518_1	309801.trd_1222	8.449e-72	252.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi,27Y17@189775|Thermomicrobia	189775|Thermomicrobia	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRD1_k127_5418735_0	1120973.AQXL01000124_gene2358	6.259e-62	222.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,279HQ@186823|Alicyclobacillaceae	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_5418735_1	1444309.JAQG01000012_gene2070	3.255e-37	147.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,26T15@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
SRD1_k127_5511060_3	903818.KI912268_gene3171	8.038e-08	57.0	COG0227@1|root,COG0227@2|Bacteria,3Y5KC@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRD1_k127_5511060_2	1499680.CCFE01000024_gene2790	7.776e-25	110.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,4HIS4@91061|Bacilli,1ZG6I@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yloU	-	-	-	-	-	-	-	-	-	-	-	Asp23
SRD1_k127_5511060_0	1128421.JAGA01000002_gene200	1.178e-121	409.0	COG1461@1|root,COG1461@2|Bacteria,2NPHY@2323|unclassified Bacteria	2|Bacteria	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRD1_k127_5511060_1	1007103.AFHW01000092_gene3618	6.492e-25	109.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,26S8K@186822|Paenibacillaceae	91061|Bacilli	S	DegV family	degV3	-	-	-	-	-	-	-	-	-	-	-	DegV
SRD1_k127_5553155_15	485913.Krac_12259	5.64e-21	98.0	COG1028@1|root,COG1028@2|Bacteria,2G8G1@200795|Chloroflexi	485913.Krac_12259|-	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5553155_12	478801.Ksed_26620	4.479e-34	144.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,1ZWUA@145357|Dermacoccaceae	201174|Actinobacteria	H	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRD1_k127_5553155_17	1124983.PFLCHA0_c32970	1.686e-12	76.0	COG0500@1|root,COG2226@2|Bacteria,1R51W@1224|Proteobacteria,1SFJF@1236|Gammaproteobacteria,1YPU1@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRD1_k127_5553155_13	525904.Tter_2084	2.815e-30	125.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	CBS
SRD1_k127_5553155_20	476272.RUMHYD_02189	2.691e-05	50.0	COG0607@1|root,COG0607@2|Bacteria,1U0PW@1239|Firmicutes,24RKU@186801|Clostridia,3Y0JZ@572511|Blautia	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRD1_k127_5553155_0	926560.KE387027_gene419	4.843e-171	554.0	COG0477@1|root,COG0477@2|Bacteria,1WMC1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD1_k127_5553155_14	1459636.NTE_00536	1.687e-23	109.0	COG0346@1|root,arCOG02708@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRD1_k127_5553155_19	1174684.EBMC1_07630	8.759e-07	59.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2U1MH@28211|Alphaproteobacteria,2K0EG@204457|Sphingomonadales	204457|Sphingomonadales	L	endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRD1_k127_5553155_10	1120949.KB903325_gene3072	4.352e-41	169.0	COG1524@1|root,COG1524@2|Bacteria,2HH0Q@201174|Actinobacteria,4DAQP@85008|Micromonosporales	201174|Actinobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_2,Phosphodiest
SRD1_k127_5553155_21	44060.JODL01000004_gene2659	0.0008835	51.0	COG0697@1|root,COG0697@2|Bacteria,2GKVT@201174|Actinobacteria	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	ydeD	-	-	-	-	-	-	-	-	-	-	-	EamA
SRD1_k127_5553155_16	1080067.BAZH01000013_gene930	2.269e-19	95.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1MVSA@1224|Proteobacteria,1RP1K@1236|Gammaproteobacteria,3WWBH@544|Citrobacter	1236|Gammaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	yeaP	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621	2.7.7.65	ko:K13069,ko:K21021	ko02025,map02025	-	R08057	-	ko00000,ko00001,ko01000	-	-	-	GAF_2,GAF_3,GGDEF
SRD1_k127_5553155_1	765420.OSCT_0800	6.864e-164	542.0	COG0318@1|root,COG0318@2|Bacteria,2G83V@200795|Chloroflexi,376U1@32061|Chloroflexia	32061|Chloroflexia	IQ	AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRD1_k127_5553155_3	1183438.GKIL_0183	8.499e-92	327.0	COG1893@1|root,COG1893@2|Bacteria,1G47S@1117|Cyanobacteria	1117|Cyanobacteria	H	2-dehydropantoate 2-reductase	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRD1_k127_5553155_9	1382306.JNIM01000001_gene1607	2.382e-46	186.0	COG1802@1|root,COG1802@2|Bacteria,2G993@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRD1_k127_5553155_18	1027371.GOALK_094_00100	2.836e-10	72.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4GAKJ@85026|Gordoniaceae	201174|Actinobacteria	E	Receptor family ligand binding region	livK	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRD1_k127_5553155_8	1194972.MVAC_25890	3.831e-62	224.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,232H0@1762|Mycobacteriaceae	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K11956	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	BPD_transp_2,CarboxypepD_reg
SRD1_k127_5553155_5	1121877.JQKF01000012_gene340	9.611e-75	275.0	COG4177@1|root,COG4177@2|Bacteria,2H4RR@201174|Actinobacteria	201174|Actinobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRD1_k127_5553155_6	525909.Afer_0505	1.258e-66	237.0	COG0411@1|root,COG0411@2|Bacteria,2I3Z1@201174|Actinobacteria,4CP54@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRD1_k127_5553155_7	1121877.JQKF01000012_gene338	8.018e-65	231.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4CN2Y@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRD1_k127_5553155_4	1123401.JHYQ01000012_gene2940	3.638e-83	285.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,1RPYA@1236|Gammaproteobacteria,460GJ@72273|Thiotrichales	72273|Thiotrichales	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRD1_k127_5553155_2	1449353.JQMQ01000005_gene5069	2.926e-152	512.0	COG3292@1|root,COG3386@1|root,COG3292@2|Bacteria,COG3386@2|Bacteria,2IAXB@201174|Actinobacteria,2NEJK@228398|Streptacidiphilus	201174|Actinobacteria	GT	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5553155_11	1189612.A33Q_4395	3.414e-36	143.0	COG0329@1|root,COG0329@2|Bacteria,4NFIH@976|Bacteroidetes	976|Bacteroidetes	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRD1_k127_5564941_4	751944.HALDL1_11470	1.631e-14	77.0	COG0402@1|root,arCOG00697@2157|Archaea,2XUBV@28890|Euryarchaeota,23UGS@183963|Halobacteria	183963|Halobacteria	F	COG0402 Cytosine deaminase and related metal-dependent hydrolases	-	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_3
SRD1_k127_5564941_1	1382356.JQMP01000003_gene1479	1.644e-116	389.0	COG2233@1|root,COG2233@2|Bacteria,2G8VZ@200795|Chloroflexi	200795|Chloroflexi	F	Permease family	-	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
SRD1_k127_5564941_2	405948.SACE_4022	5.882e-116	396.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4E8T3@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C,MCD,MCD_N
SRD1_k127_5564941_0	1382356.JQMP01000003_gene1474	9.48e-121	394.0	COG1878@1|root,COG1878@2|Bacteria,2GBE2@200795|Chloroflexi,27Z29@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRD1_k127_5564941_3	1394178.AWOO02000032_gene4940	4.002e-64	229.0	COG1319@1|root,COG1319@2|Bacteria,2GP37@201174|Actinobacteria,4EFM4@85012|Streptosporangiales	201174|Actinobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRD1_k127_5579904_1	649638.Trad_0584	1.973e-77	274.0	COG0513@1|root,COG0513@2|Bacteria,1WKZ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRD1_k127_5579904_2	1121472.AQWN01000006_gene1710	0.0001746	48.0	COG0745@1|root,COG0745@2|Bacteria,1V9RJ@1239|Firmicutes,24PV6@186801|Clostridia	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SRD1_k127_5579904_0	395495.Lcho_2036	1.48e-129	439.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,1KKDW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRD1_k127_5613962_0	1382306.JNIM01000001_gene3604	4.021e-18	97.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
SRD1_k127_5613962_2	1177594.MIC448_1610006	1.419e-13	78.0	COG0671@1|root,COG0671@2|Bacteria,2I9FB@201174|Actinobacteria,4FMIK@85023|Microbacteriaceae	201174|Actinobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRD1_k127_5616327_0	518766.Rmar_1231	6.396e-196	620.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1FIW6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
SRD1_k127_5616327_1	314254.OA2633_01539	4.836e-89	301.0	COG1024@1|root,COG1024@2|Bacteria,1NDT7@1224|Proteobacteria,2U2R9@28211|Alphaproteobacteria,43XFU@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD1_k127_5616327_4	1123288.SOV_5c00610	6.032e-11	74.0	2CIPC@1|root,2Z9HB@2|Bacteria	2|Bacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRD1_k127_5616327_2	1122622.ATWJ01000009_gene3090	7.037e-33	139.0	COG0454@1|root,COG1042@1|root,COG0456@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4FEVV@85021|Intrasporangiaceae	201174|Actinobacteria	CJ	Multidrug ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRD1_k127_5616327_3	1068980.ARVW01000001_gene1143	2.202e-13	76.0	COG1280@1|root,COG1280@2|Bacteria,2ICJX@201174|Actinobacteria,4EBWK@85010|Pseudonocardiales	201174|Actinobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRD1_k127_5698625_0	266117.Rxyl_2839	6.898e-277	869.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4CPP1@84995|Rubrobacteria	84995|Rubrobacteria	C	xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRD1_k127_5702857_0	292459.STH1524	9.194e-60	217.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia	186801|Clostridia	J	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRD1_k127_5702857_1	1128421.JAGA01000003_gene3155	2.459e-54	204.0	COG0130@1|root,COG0130@2|Bacteria,2NP9J@2323|unclassified Bacteria	2|Bacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
SRD1_k127_5702857_2	357808.RoseRS_3756	1.046e-26	124.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi,374TG@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM riboflavin biosynthesis protein RibF	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRD1_k127_5746513_11	404380.Gbem_2673	1.187e-28	119.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,42QF7@68525|delta/epsilon subdivisions,2WJAU@28221|Deltaproteobacteria,43VY7@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Sensor histidine kinase, HAMP domain-containing	-	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_9,Response_reg
SRD1_k127_5746513_3	2002.JOEQ01000048_gene7447	7.662e-89	301.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4EM3I@85012|Streptosporangiales	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRD1_k127_5746513_8	926569.ANT_27760	3.722e-37	150.0	COG0704@1|root,COG0704@2|Bacteria,2G6HD@200795|Chloroflexi	200795|Chloroflexi	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRD1_k127_5746513_5	1120947.ATUX01000013_gene1171	2.525e-63	227.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4D3E8@85005|Actinomycetales	201174|Actinobacteria	KT	response regulator	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_5746513_4	768710.DesyoDRAFT_3277	3.092e-75	263.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,26553@186807|Peptococcaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRD1_k127_5746513_6	1123371.ATXH01000005_gene2120	2.195e-61	235.0	COG0581@1|root,COG0581@2|Bacteria,2GGUY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRD1_k127_5746513_9	204669.Acid345_3130	1.532e-33	137.0	COG1392@1|root,COG1392@2|Bacteria,3Y58U@57723|Acidobacteria,2JK4H@204432|Acidobacteriia	204432|Acidobacteriia	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRD1_k127_5746513_7	1283299.AUKG01000004_gene1132	7.047e-39	156.0	COG1392@1|root,COG1392@2|Bacteria,2GJME@201174|Actinobacteria,4CPW4@84995|Rubrobacteria	84995|Rubrobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRD1_k127_5746513_2	351607.Acel_2027	1.141e-94	321.0	COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria,4ERKR@85013|Frankiales	201174|Actinobacteria	P	phosphate transporter	pit	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	iNJ661.Rv0545c,iNJ661.Rv2281	PHO4
SRD1_k127_5746513_10	1463845.JOIG01000003_gene5175	5.927e-32	130.0	COG1051@1|root,COG1051@2|Bacteria,2I2N2@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the NUDIX hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRD1_k127_5746513_1	479434.Sthe_1495	1.016e-107	360.0	COG2022@1|root,COG2022@2|Bacteria,2G6DX@200795|Chloroflexi,27XT9@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
SRD1_k127_5746513_12	234267.Acid_6375	2.134e-19	102.0	COG0352@1|root,COG0352@2|Bacteria,3Y53Y@57723|Acidobacteria	57723|Acidobacteria	H	PFAM thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SRD1_k127_5746513_14	272134.KB731324_gene2374	1.004e-11	75.0	COG2104@1|root,COG2104@2|Bacteria,1G986@1117|Cyanobacteria,1HCXC@1150|Oscillatoriales	1117|Cyanobacteria	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	iJN678.ycf40	ThiS
SRD1_k127_5746513_0	1382306.JNIM01000001_gene2552	5.757e-108	369.0	COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRD1_k127_5746513_13	255470.cbdbA1696	3.065e-12	76.0	COG0294@1|root,COG0294@2|Bacteria,2G6A6@200795|Chloroflexi,34D72@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Pterin binding enzyme	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRD1_k127_5806535_0	234267.Acid_6457	5.283e-101	346.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
SRD1_k127_5806535_4	1122138.AQUZ01000004_gene891	0.0002518	51.0	COG3080@1|root,COG3080@2|Bacteria,2IMEN@201174|Actinobacteria	201174|Actinobacteria	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdD	-	-	ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1555	Fumarate_red_D
SRD1_k127_5806535_3	1123024.AUII01000011_gene4420	3.514e-06	54.0	COG3029@1|root,COG3029@2|Bacteria,2IQ2Z@201174|Actinobacteria	201174|Actinobacteria	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdC	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Fumarate_red_C
SRD1_k127_5806535_1	443218.AS9A_2959	5.053e-88	298.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,235N9@1762|Mycobacteriaceae	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1553	Fer2_3,Fer4_8
SRD1_k127_5806535_2	1123388.AQWU01000061_gene931	7.22e-20	90.0	COG1053@1|root,COG1053@2|Bacteria,1WIYZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	succinate dehydrogenase or fumarate reductase, flavoprotein	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRD1_k127_5814955_1	935866.JAER01000040_gene506	4.567e-05	47.0	2DNW5@1|root,32ZGI@2|Bacteria,2IQ5T@201174|Actinobacteria,4DS78@85009|Propionibacteriales	201174|Actinobacteria	S	Rho termination factor, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
SRD1_k127_5814955_0	861299.J421_1576	4.33e-10	72.0	COG4447@1|root,COG4447@2|Bacteria,1ZTS2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5916543_3	595593.JREV01000048_gene1050	1.133e-29	128.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,1W7JA@1268|Micrococcaceae	201174|Actinobacteria	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRD1_k127_5916543_1	1380370.JIBA01000015_gene304	2.822e-90	310.0	COG2041@1|root,COG2041@2|Bacteria,2GIZH@201174|Actinobacteria,4FI2F@85021|Intrasporangiaceae	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB,Oxidored_molyb
SRD1_k127_5916543_4	1122138.AQUZ01000070_gene130	9.533e-09	64.0	COG1846@1|root,COG1846@2|Bacteria,2IFRN@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRD1_k127_5916543_2	1382356.JQMP01000003_gene1386	1.924e-45	170.0	COG2353@1|root,COG2353@2|Bacteria,2G6G9@200795|Chloroflexi,27Y8W@189775|Thermomicrobia	189775|Thermomicrobia	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRD1_k127_5916543_0	1532558.JL39_00460	3.175e-106	358.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,2TR29@28211|Alphaproteobacteria,4BDF2@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRD1_k127_5916543_5	1379698.RBG1_1C00001G1769	9.869e-07	57.0	COG0640@1|root,COG0640@2|Bacteria,2NQ1G@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRD1_k127_5942341_2	266117.Rxyl_2822	9.648e-62	224.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria,4CPI4@84995|Rubrobacteria	84995|Rubrobacteria	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
SRD1_k127_5942341_6	383381.EH30_02315	3.019e-19	97.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2TV3Q@28211|Alphaproteobacteria,2K3ZW@204457|Sphingomonadales	204457|Sphingomonadales	L	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRD1_k127_5942341_1	543632.JOJL01000019_gene10100	9.532e-66	233.0	COG0428@1|root,COG0428@2|Bacteria,2IBHZ@201174|Actinobacteria	201174|Actinobacteria	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRD1_k127_5942341_5	357808.RoseRS_4549	3.397e-46	175.0	COG1321@1|root,COG1321@2|Bacteria,2G7DY@200795|Chloroflexi,3771X@32061|Chloroflexia	32061|Chloroflexia	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRD1_k127_5942341_4	1183438.GKIL_3645	1.25e-48	188.0	COG1970@1|root,COG1970@2|Bacteria,1G829@1117|Cyanobacteria	1117|Cyanobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRD1_k127_5942341_0	1123504.JQKD01000012_gene1236	6.952e-80	278.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,2VJXC@28216|Betaproteobacteria,4ACYX@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRD1_k127_5942341_7	292459.STH2132	1.984e-17	97.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1VAC5@1239|Firmicutes,25EMF@186801|Clostridia	186801|Clostridia	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1,Peptidase_M23
SRD1_k127_5942341_3	525909.Afer_1432	1.197e-48	182.0	COG0560@1|root,COG3320@1|root,COG0560@2|Bacteria,COG3320@2|Bacteria,2GJVX@201174|Actinobacteria,4CMQQ@84992|Acidimicrobiia	84992|Acidimicrobiia	EQ	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,NAD_binding_4
SRD1_k127_5957745_5	696281.Desru_0764	7.418e-18	89.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,24RC0@186801|Clostridia,262C8@186807|Peptococcaceae	186801|Clostridia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS01470	ACPS
SRD1_k127_5957745_0	379066.GAU_2427	8.113e-185	596.0	COG0449@1|root,COG0449@2|Bacteria,1ZSTI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRD1_k127_5957745_6	1051632.TPY_0876	5.69e-08	65.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,24GKC@186801|Clostridia	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
SRD1_k127_5957745_3	264732.Moth_2248	6.524e-62	228.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,42FDQ@68295|Thermoanaerobacterales	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
SRD1_k127_5957745_2	1151117.AJLF01000001_gene1236	3.613e-87	297.0	COG0448@1|root,arCOG00912@2157|Archaea,2XTI4@28890|Euryarchaeota,242ZT@183968|Thermococci	183968|Thermococci	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRD1_k127_5957745_1	928724.SacglDRAFT_03265	9.963e-150	495.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DZ2U@85010|Pseudonocardiales	201174|Actinobacteria	I	AMP-forming long-chain acyl-CoA synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRD1_k127_5957745_4	67281.JNZZ01000003_gene4289	2.558e-34	145.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,417NI@629295|Streptomyces griseus group	201174|Actinobacteria	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRD1_k127_5960519_1	1382306.JNIM01000001_gene3038	3.229e-32	132.0	COG1457@1|root,COG1457@2|Bacteria,2G9KC@200795|Chloroflexi	200795|Chloroflexi	F	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
SRD1_k127_5960519_0	1120973.AQXL01000123_gene3072	6.201e-85	293.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,2786M@186823|Alicyclobacillaceae	91061|Bacilli	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
SRD1_k127_5960519_2	545243.BAEV01000087_gene2355	0.0002365	52.0	2DN90@1|root,32W6G@2|Bacteria,1VC37@1239|Firmicutes,24KFW@186801|Clostridia,36JZU@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5961846_0	479434.Sthe_0519	1.846e-82	283.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi,27XTR@189775|Thermomicrobia	189775|Thermomicrobia	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRD1_k127_5961846_1	479434.Sthe_0523	1.26e-38	153.0	COG1040@1|root,COG1040@2|Bacteria,2G6WB@200795|Chloroflexi,27YJE@189775|Thermomicrobia	189775|Thermomicrobia	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRD1_k127_5964058_0	1440774.Y900_004970	1.264e-112	370.0	COG0330@1|root,COG0330@2|Bacteria,2GKFP@201174|Actinobacteria,2349A@1762|Mycobacteriaceae	201174|Actinobacteria	O	SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRD1_k127_5968916_10	316274.Haur_3472	2.34e-55	214.0	COG0457@1|root,COG0515@1|root,COG3266@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3266@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
SRD1_k127_5968916_4	671143.DAMO_0479	7.666e-89	314.0	COG3437@1|root,COG3437@2|Bacteria,2NPBP@2323|unclassified Bacteria	2|Bacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
SRD1_k127_5968916_1	247490.KSU1_C0338	3.469e-119	425.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,2J515@203682|Planctomycetes	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
SRD1_k127_5968916_19	1125863.JAFN01000001_gene578	2.056e-27	118.0	COG0784@1|root,COG0784@2|Bacteria,1QU3I@1224|Proteobacteria,43BYJ@68525|delta/epsilon subdivisions,2X79G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRD1_k127_5968916_20	305900.GV64_12080	3.298e-17	91.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T3S9@1236|Gammaproteobacteria,1XR40@135619|Oceanospirillales	1224|Proteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg,SBP_bac_3
SRD1_k127_5968916_11	1298863.AUEP01000008_gene1319	3.611e-55	218.0	COG5002@1|root,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
SRD1_k127_5968916_8	309801.trd_A0706	7.117e-77	280.0	COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi,27XY2@189775|Thermomicrobia	189775|Thermomicrobia	M	SIS domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
SRD1_k127_5968916_14	1120797.KB908260_gene4211	3.623e-52	207.0	COG2971@1|root,COG2971@2|Bacteria,2GKNB@201174|Actinobacteria,237W0@1762|Mycobacteriaceae	201174|Actinobacteria	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRD1_k127_5968916_9	502025.Hoch_1477	9.326e-68	254.0	COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,430VJ@68525|delta/epsilon subdivisions,2WVQI@28221|Deltaproteobacteria,2Z0VP@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRD1_k127_5968916_13	1118054.CAGW01000068_gene1878	2.893e-53	201.0	COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,26QZT@186822|Paenibacillaceae	91061|Bacilli	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
SRD1_k127_5968916_0	66897.DJ64_14965	5.944e-126	431.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRD1_k127_5968916_5	1348663.KCH_58750	1.48e-88	303.0	COG0395@1|root,COG0395@2|Bacteria,2GKEE@201174|Actinobacteria,2M0BG@2063|Kitasatospora	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	dasC	-	-	ko:K17331	ko02010,map02010	M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.33	-	-	BPD_transp_1
SRD1_k127_5968916_6	351607.Acel_0553	2.374e-83	287.0	COG1175@1|root,COG1175@2|Bacteria,2GX5P@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K17330	ko02010,map02010	M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.33	-	-	BPD_transp_1
SRD1_k127_5968916_3	351607.Acel_0552	7.342e-109	366.0	COG1653@1|root,COG1653@2|Bacteria,2GN08@201174|Actinobacteria,4ETH8@85013|Frankiales	201174|Actinobacteria	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027,ko:K17329	ko02010,map02010	M00207,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.33	-	-	SBP_bac_1,SBP_bac_8
SRD1_k127_5968916_7	1394178.AWOO02000081_gene2216	4.732e-81	278.0	COG2188@1|root,COG2188@2|Bacteria,2GJZ1@201174|Actinobacteria,4EJBH@85012|Streptosporangiales	201174|Actinobacteria	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRD1_k127_5968916_21	1122236.KB905141_gene1793	0.0002115	47.0	COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,2VVQ9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Transglycosylase-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRD1_k127_5968916_16	1003195.SCAT_3042	1.23e-41	163.0	COG4894@1|root,COG4894@2|Bacteria,2GKWI@201174|Actinobacteria	201174|Actinobacteria	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
SRD1_k127_5968916_17	28444.JODQ01000002_gene4110	1.32e-40	162.0	COG1280@1|root,COG1280@2|Bacteria,2GMDP@201174|Actinobacteria,4EIVP@85012|Streptosporangiales	201174|Actinobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRD1_k127_5968916_12	1242864.D187_007162	5.128e-54	211.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,2YV6M@29|Myxococcales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284,ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3,1.A.35.4	-	-	CorA
SRD1_k127_5968916_15	136273.GY22_15995	2.779e-46	186.0	COG2227@1|root,COG2227@2|Bacteria,2IIE2@201174|Actinobacteria	201174|Actinobacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.11	ko:K03428	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R04237	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRD1_k127_5968916_2	479434.Sthe_0784	1.095e-118	396.0	COG0498@1|root,COG0498@2|Bacteria,2G5RK@200795|Chloroflexi,27Y4R@189775|Thermomicrobia	189775|Thermomicrobia	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD1_k127_5968916_18	1079986.JH164861_gene7370	2.031e-39	147.0	COG1073@1|root,COG1073@2|Bacteria,2I345@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRD1_k127_5977437_2	1451189.CFAL_04525	3.898e-16	82.0	COG0296@1|root,COG0296@2|Bacteria,2GMIS@201174|Actinobacteria,22K85@1653|Corynebacteriaceae	201174|Actinobacteria	G	4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase	treZ	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016787,GO:0016798,GO:0030978,GO:0030980,GO:0033942,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0071704,GO:1901575,GO:1901576	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SRD1_k127_5977437_0	713586.KB900536_gene49	1.642e-255	811.0	COG3280@1|root,COG3280@2|Bacteria,1QTVK@1224|Proteobacteria,1T1IP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	synthase	treY	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
SRD1_k127_5977437_1	316274.Haur_1630	5.342e-53	192.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	yuaD	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRD1_k127_5977437_3	208444.JNYY01000001_gene5218	3.351e-14	74.0	COG0596@1|root,COG0596@2|Bacteria,2GKT5@201174|Actinobacteria,4E084@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRD1_k127_5984705_1	205918.Psyr_2881	1.006e-99	334.0	COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,1S02V@1236|Gammaproteobacteria,1Z6BR@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	O	Papain cysteine protease family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
SRD1_k127_5984705_2	1123322.KB904698_gene4698	4.88e-32	132.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRD1_k127_5984705_3	1386089.N865_18425	3.143e-07	61.0	2B1TT@1|root,31U9S@2|Bacteria,2GTPW@201174|Actinobacteria,4FHP5@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_5984705_0	1386089.N865_20905	5.556e-114	372.0	COG2267@1|root,COG2267@2|Bacteria,2HEX8@201174|Actinobacteria,4FIB8@85021|Intrasporangiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C
SRD1_k127_5988401_1	313589.JNB_09959	2.549e-50	198.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	BACON,DUF285,DUF4955,DUF4988,LRR_4,LRR_5,LRR_8
SRD1_k127_5988401_2	305700.B447_11282	2.539e-18	95.0	COG0500@1|root,COG2226@2|Bacteria,1REVA@1224|Proteobacteria,2VMI7@28216|Betaproteobacteria,2KVP6@206389|Rhodocyclales	206389|Rhodocyclales	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRD1_k127_5988401_3	1392490.JHZX01000001_gene1648	2.337e-07	63.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,1I47M@117743|Flavobacteriia	976|Bacteroidetes	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRD1_k127_5988401_0	1125863.JAFN01000001_gene886	4.791e-80	272.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42N1P@68525|delta/epsilon subdivisions,2WM2V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRD1_k127_6013875_0	557599.MKAN_26255	5.539e-73	258.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,234XD@1762|Mycobacteriaceae	201174|Actinobacteria	S	Contains patatin domain. This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40 of the total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRD1_k127_6013875_5	357808.RoseRS_1631	5.252e-15	89.0	COG0823@1|root,COG0823@2|Bacteria,2G8Z9@200795|Chloroflexi,376BX@32061|Chloroflexia	32061|Chloroflexia	U	PFAM WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRD1_k127_6013875_1	1382306.JNIM01000001_gene253	6.308e-57	211.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRD1_k127_6013875_4	272134.KB731324_gene3782	1.029e-18	98.0	2EWB1@1|root,33PPS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
SRD1_k127_6013875_3	1192034.CAP_5968	4.672e-21	98.0	COG4430@1|root,COG4430@2|Bacteria,1QZAG@1224|Proteobacteria	1224|Proteobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
SRD1_k127_6013875_2	749927.AMED_1094	3.562e-33	139.0	COG2129@1|root,COG2129@2|Bacteria,2ICBG@201174|Actinobacteria,4DYD7@85010|Pseudonocardiales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRD1_k127_6015963_0	383372.Rcas_4102	8.798e-139	453.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi,3750V@32061|Chloroflexia	32061|Chloroflexia	I	PFAM carboxyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRD1_k127_6015963_2	309801.trd_0497	1.545e-71	255.0	COG0583@1|root,COG0583@2|Bacteria,2G70X@200795|Chloroflexi,27YSC@189775|Thermomicrobia	189775|Thermomicrobia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRD1_k127_6015963_6	504832.OCAR_7174	9.814e-07	61.0	2CIPC@1|root,2Z9HB@2|Bacteria,1R3W8@1224|Proteobacteria,2TST7@28211|Alphaproteobacteria,3JT48@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRD1_k127_6015963_3	35754.JNYJ01000069_gene4216	1.909e-56	209.0	COG0702@1|root,COG0702@2|Bacteria,2IT8A@201174|Actinobacteria,4DH5S@85008|Micromonosporales	201174|Actinobacteria	GM	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRD1_k127_6015963_1	118163.Ple7327_4336	4.443e-136	460.0	COG2303@1|root,COG2303@2|Bacteria,1GB9F@1117|Cyanobacteria	1117|Cyanobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,NAD_binding_8
SRD1_k127_6015963_5	1121946.AUAX01000034_gene6823	2.185e-07	64.0	COG3170@1|root,COG3170@2|Bacteria,2I40K@201174|Actinobacteria,4D8QC@85008|Micromonosporales	201174|Actinobacteria	NU	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
SRD1_k127_6017750_1	926554.KI912633_gene3829	1.399e-46	171.0	COG0066@1|root,COG0066@2|Bacteria,1WIK6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRD1_k127_6017750_0	1382306.JNIM01000001_gene3339	8.335e-147	473.0	COG0129@1|root,COG0129@2|Bacteria,2G67Z@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRD1_k127_6021455_0	290397.Adeh_1707	0.0	998.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YUPG@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRD1_k127_6034217_0	1382306.JNIM01000001_gene3912	4.861e-121	392.0	COG1219@1|root,COG1219@2|Bacteria,2G661@200795|Chloroflexi	200795|Chloroflexi	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRD1_k127_6034217_5	449447.MAE_62730	3.503e-06	58.0	COG1219@1|root,COG1219@2|Bacteria,1G04H@1117|Cyanobacteria	1117|Cyanobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRD1_k127_6034217_2	648996.Theam_0136	4.415e-88	295.0	COG0740@1|root,COG0740@2|Bacteria,2G3IM@200783|Aquificae	200783|Aquificae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRD1_k127_6034217_3	635013.TherJR_2564	1.91e-63	236.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,260PB@186807|Peptococcaceae	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRD1_k127_6034217_1	926550.CLDAP_37440	3.114e-101	357.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
SRD1_k127_6034217_4	269797.Mbar_A0234	1.179e-35	153.0	COG2244@1|root,arCOG02209@2157|Archaea,2XSUR@28890|Euryarchaeota,2NAAG@224756|Methanomicrobia	224756|Methanomicrobia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SRD1_k127_6034217_6	1122149.BACN01000051_gene147	1.046e-05	53.0	COG4990@1|root,COG4990@2|Bacteria,1VE2G@1239|Firmicutes,4HMDI@91061|Bacilli,3F6FB@33958|Lactobacillaceae	91061|Bacilli	M	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
SRD1_k127_6040307_0	319795.Dgeo_1999	4.971e-39	166.0	COG3437@1|root,COG3437@2|Bacteria,1WJ3D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PFAM HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD_5,PAS_3
SRD1_k127_6041762_1	153721.MYP_2285	1.072e-52	196.0	2DKU7@1|root,30BG5@2|Bacteria,4NNSQ@976|Bacteroidetes,47PSB@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
SRD1_k127_6041762_0	1278073.MYSTI_03014	1.979e-71	248.0	COG3361@1|root,COG3361@2|Bacteria	2|Bacteria	S	conserved protein (COG2071)	-	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
SRD1_k127_6041762_2	1033730.CAHG01000012_gene2361	7.302e-05	46.0	COG0346@1|root,COG0346@2|Bacteria,2IQ7F@201174|Actinobacteria,4DSTU@85009|Propionibacteriales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRD1_k127_6061034_0	1449126.JQKL01000064_gene48	0.0	1057.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,267JY@186813|unclassified Clostridiales	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRD1_k127_6068966_1	1226322.HMPREF1545_01814	5.047e-05	47.0	COG1595@1|root,COG1595@2|Bacteria,1V57W@1239|Firmicutes,25BIS@186801|Clostridia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_6068966_0	1122927.KB895417_gene2981	2.316e-12	75.0	COG1595@1|root,COG1595@2|Bacteria,1V3WW@1239|Firmicutes,4HHBT@91061|Bacilli,26UWJ@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_6073298_0	1382306.JNIM01000001_gene244	5.748e-87	304.0	COG0849@1|root,COG0849@2|Bacteria	2|Bacteria	D	cell division	-	-	-	-	-	-	-	-	-	-	-	-	FtsA
SRD1_k127_6073298_6	370438.PTH_1065	2.716e-31	132.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,2622P@186807|Peptococcaceae	186801|Clostridia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRD1_k127_6073298_3	401526.TcarDRAFT_0046	1.065e-44	177.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4H20Z@909932|Negativicutes	909932|Negativicutes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRD1_k127_6073298_4	1122223.KB890688_gene1782	2.528e-44	177.0	COG0169@1|root,COG0169@2|Bacteria,1WIM8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0048037,GO:0050661,GO:0050662,GO:0097159,GO:1901265,GO:1901363	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRD1_k127_6073298_10	1121468.AUBR01000002_gene702	5.114e-11	75.0	COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,24HC0@186801|Clostridia,42FQ9@68295|Thermoanaerobacterales	186801|Clostridia	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRD1_k127_6073298_8	877455.Metbo_2368	3.898e-16	85.0	COG3428@1|root,arCOG04619@2157|Archaea,2XZYG@28890|Euryarchaeota,23P86@183925|Methanobacteria	183925|Methanobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRD1_k127_6073298_7	1280953.HOC_05523	2.78e-27	121.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,43XTC@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRD1_k127_6073298_1	1128421.JAGA01000003_gene2989	6.37e-70	253.0	COG0337@1|root,COG0337@2|Bacteria,2NP5Z@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRD1_k127_6073298_5	373903.Hore_06130	1.123e-39	165.0	COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,24JBK@186801|Clostridia,3WBRR@53433|Halanaerobiales	186801|Clostridia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRD1_k127_6073298_2	1304880.JAGB01000001_gene84	8.807e-50	186.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRD1_k127_6073298_9	1122217.KB899576_gene1882	2.99e-11	68.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4H4DV@909932|Negativicutes	909932|Negativicutes	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
SRD1_k127_6094735_5	1210045.ALNP01000037_gene2322	1.862e-18	90.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria	201174|Actinobacteria	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRD1_k127_6094735_3	1313172.YM304_09910	1.618e-66	235.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4CMXI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRD1_k127_6094735_4	1121472.AQWN01000005_gene2528	3.624e-21	100.0	COG0746@1|root,COG0746@2|Bacteria,1VA6T@1239|Firmicutes,24JG6@186801|Clostridia,262DJ@186807|Peptococcaceae	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRD1_k127_6094735_1	1382306.JNIM01000001_gene1934	1.141e-94	321.0	COG2159@1|root,COG2159@2|Bacteria,2G8DN@200795|Chloroflexi	200795|Chloroflexi	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRD1_k127_6094735_0	479434.Sthe_2381	2.752e-265	831.0	COG0365@1|root,COG0365@2|Bacteria,2G830@200795|Chloroflexi,27XH3@189775|Thermomicrobia	189775|Thermomicrobia	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRD1_k127_6094735_6	670292.JH26_21790	0.0007497	46.0	COG2044@1|root,COG2044@2|Bacteria,1NI0Y@1224|Proteobacteria,2UJJT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRD1_k127_6094735_2	1187851.A33M_0926	3.202e-77	274.0	COG2807@1|root,COG2807@2|Bacteria,1MXGT@1224|Proteobacteria,2TVC9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Major facilitator superfamily	-	-	-	ko:K03449	-	-	-	-	ko00000,ko02000	2.A.1.17	-	-	MFS_1
SRD1_k127_6098417_6	1123269.NX02_16250	6.712e-06	57.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,2UBXS@28211|Alphaproteobacteria,2K5AR@204457|Sphingomonadales	204457|Sphingomonadales	C	nad(P) transhydrogenase subunit alpha	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRD1_k127_6098417_3	483219.LILAB_36415	4.004e-23	104.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
SRD1_k127_6098417_2	443218.AS9A_3060	2.137e-23	105.0	COG1846@1|root,COG1846@2|Bacteria,2I18D@201174|Actinobacteria,237M1@1762|Mycobacteriaceae	201174|Actinobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRD1_k127_6098417_5	479432.Sros_0565	6.253e-22	102.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	1.13.11.24	ko:K07155	-	-	-	-	ko00000,ko01000	-	-	-	Cupin_2
SRD1_k127_6098417_7	1122135.KB893171_gene2117	0.0002535	50.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,2TSK7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain	regA	GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
SRD1_k127_6098417_1	644966.Tmar_0771	3.262e-33	138.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,3WD8H@538999|Clostridiales incertae sedis	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_6098417_4	1121440.AUMA01000010_gene364	7.884e-23	110.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42U4X@68525|delta/epsilon subdivisions,2WQCD@28221|Deltaproteobacteria,2MA4N@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_3,PAS_9
SRD1_k127_6098417_0	742818.HMPREF9451_01639	6.802e-38	147.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CU8E@84998|Coriobacteriia	84998|Coriobacteriia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRD1_k127_6110215_1	1382356.JQMP01000003_gene1584	4.771e-98	332.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,27XKK@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRD1_k127_6110215_0	1242864.D187_002420	1.418e-195	633.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42MQJ@68525|delta/epsilon subdivisions,2WJIX@28221|Deltaproteobacteria,2YX9E@29|Myxococcales	28221|Deltaproteobacteria	P	Hemerythrin HHE cation binding domain	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
SRD1_k127_6110215_2	298655.KI912266_gene2830	1.672e-32	135.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria,4ETKN@85013|Frankiales	201174|Actinobacteria	C	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRD1_k127_6110215_3	207559.Dde_0589	1.14e-12	74.0	COG0589@1|root,COG0589@2|Bacteria,1PDTQ@1224|Proteobacteria,42T4W@68525|delta/epsilon subdivisions,2WS67@28221|Deltaproteobacteria,2MD3W@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRD1_k127_6120936_0	742743.HMPREF9453_01577	1.067e-22	103.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4H57T@909932|Negativicutes	909932|Negativicutes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRD1_k127_6120936_1	1157490.EL26_18935	1.348e-17	92.0	2DBDP@1|root,32TXA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6120936_2	471852.Tcur_4934	9.202e-05	51.0	COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,2GNQ9@201174|Actinobacteria,4EHDW@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,TPR_12
SRD1_k127_6125302_7	545243.BAEV01000087_gene2355	2.656e-07	58.0	2DN90@1|root,32W6G@2|Bacteria,1VC37@1239|Firmicutes,24KFW@186801|Clostridia,36JZU@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6125302_5	709986.Deima_0811	2.756e-42	169.0	COG0454@1|root,COG0454@2|Bacteria,COG0456@2|Bacteria,1WJYD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD1_k127_6125302_4	1150864.MILUP08_41973	5.606e-84	287.0	COG2141@1|root,COG2141@2|Bacteria,2GPA5@201174|Actinobacteria,4DIRB@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD1_k127_6125302_1	525909.Afer_1978	5.818e-163	531.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria	201174|Actinobacteria	C	the transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRD1_k127_6125302_6	103733.JNYO01000002_gene474	2.232e-27	124.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria,4E5KZ@85010|Pseudonocardiales	201174|Actinobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRD1_k127_6125302_2	1173027.Mic7113_5936	1.421e-120	404.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,1H7A5@1150|Oscillatoriales	1117|Cyanobacteria	C	NAD NADP transhydrogenase alpha subunit	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
SRD1_k127_6125302_0	1382359.JIAL01000001_gene135	2.046e-218	693.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,3Y3NX@57723|Acidobacteria,2JKIA@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
SRD1_k127_6125302_3	234267.Acid_7692	8.085e-95	324.0	COG1013@1|root,COG1013@2|Bacteria,3Y3NE@57723|Acidobacteria	57723|Acidobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRD1_k127_6130218_6	945713.IALB_0995	0.0004606	51.0	COG0860@1|root,COG0860@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	3.2.1.1,3.5.1.28	ko:K01176,ko:K01448,ko:K06385	ko00500,ko01100,ko01503,ko04973,map00500,map01100,map01503,map04973	M00727	R02108,R02112,R04112,R11262	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	GH13	-	Amidase_3,CHAP,Cu_amine_oxidN1,DUF4280,Glucosaminidase,Peptidase_C39_2
SRD1_k127_6130218_4	292459.STH2528	2.256e-38	151.0	COG1595@1|root,COG1595@2|Bacteria,1VD37@1239|Firmicutes,25BCE@186801|Clostridia	186801|Clostridia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRD1_k127_6130218_0	644966.Tmar_1426	2.032e-142	465.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3WCKG@538999|Clostridiales incertae sedis	186801|Clostridia	F	Adenylosuccinate lyase C-terminus	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRD1_k127_6130218_1	479434.Sthe_1292	5.772e-105	350.0	COG0152@1|root,COG0152@2|Bacteria,2G6S5@200795|Chloroflexi,27Y59@189775|Thermomicrobia	189775|Thermomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRD1_k127_6130218_5	621372.ACIH01000100_gene3616	7.539e-19	88.0	COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,26Z31@186822|Paenibacillaceae	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
SRD1_k127_6130218_2	1449126.JQKL01000015_gene2927	2.119e-96	321.0	COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,24A2E@186801|Clostridia	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRD1_k127_6130218_3	246194.CHY_1074	3.696e-52	199.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,42F8R@68295|Thermoanaerobacterales	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
SRD1_k127_6138619_1	1380390.JIAT01000015_gene5673	1.362e-78	281.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4CSCX@84995|Rubrobacteria	84995|Rubrobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRD1_k127_6138619_0	1123023.JIAI01000001_gene6681	2.335e-89	309.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4DXK6@85010|Pseudonocardiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_6138619_2	1123023.JIAI01000001_gene6727	2.286e-54	211.0	COG0845@1|root,COG0845@2|Bacteria,2IB2N@201174|Actinobacteria,4EEYJ@85010|Pseudonocardiales	201174|Actinobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
SRD1_k127_6144737_0	644282.Deba_2668	5.041e-67	243.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2WJEE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRD1_k127_6144737_2	515635.Dtur_0800	1.968e-32	129.0	COG2359@1|root,COG2359@2|Bacteria	2|Bacteria	S	Stage V sporulation protein S (SpoVS)	-	-	-	ko:K06416	-	-	-	-	ko00000	-	-	-	SpoVS
SRD1_k127_6144737_1	1121472.AQWN01000001_gene159	3.222e-53	190.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,2604A@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM metallophosphoesterase, MG_246 BB_0505 family	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SRD1_k127_6146302_3	266117.Rxyl_1872	5.325e-47	175.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4CS77@84995|Rubrobacteria	84995|Rubrobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRD1_k127_6146302_0	1123251.ATWM01000001_gene625	2.069e-55	211.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FE5K@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRD1_k127_6146302_2	1437824.BN940_05631	1.328e-50	189.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,2WGH6@28216|Betaproteobacteria,3T9MM@506|Alcaligenaceae	28216|Betaproteobacteria	I	Ndr family	pcaD	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,CMD
SRD1_k127_6146302_4	694430.Natoc_3641	3.597e-30	131.0	COG1250@1|root,arCOG00249@2157|Archaea,2Y84A@28890|Euryarchaeota,2414R@183963|Halobacteria	183963|Halobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRD1_k127_6146302_1	1075090.GOAMR_33_00750	1.476e-54	211.0	COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria,4GGMG@85026|Gordoniaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
SRD1_k127_6146302_5	452662.SJA_C2-05510	0.0008002	42.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2TTVF@28211|Alphaproteobacteria,2K2SE@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRD1_k127_6150488_1	1120950.KB892709_gene4128	4.947e-57	205.0	COG0842@1|root,COG0842@2|Bacteria,2GJGH@201174|Actinobacteria,4DP5I@85009|Propionibacteriales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRD1_k127_6150488_2	525904.Tter_2335	1.724e-29	124.0	2BHDR@1|root,32BFQ@2|Bacteria,2NRPF@2323|unclassified Bacteria	2|Bacteria	S	Putative zincin peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3267
SRD1_k127_6150488_0	1382306.JNIM01000001_gene3037	1.455e-67	233.0	COG1486@1|root,COG1486@2|Bacteria,2G5KA@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
SRD1_k127_6150844_4	479435.Kfla_1662	5.821e-08	65.0	COG1309@1|root,COG1309@2|Bacteria,2GNGT@201174|Actinobacteria,4DS1I@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD1_k127_6150844_0	1121877.JQKF01000016_gene124	1.807e-159	511.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4CMRQ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_6150844_3	189426.PODO_26290	7.955e-10	69.0	COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,4HCYJ@91061|Bacilli,26SB2@186822|Paenibacillaceae	91061|Bacilli	S	membrane transporter protein	yunE	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRD1_k127_6150844_2	401526.TcarDRAFT_0008	4.208e-14	78.0	COG0730@1|root,COG0730@2|Bacteria,1VAMI@1239|Firmicutes,4H54C@909932|Negativicutes	909932|Negativicutes	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
SRD1_k127_6150844_1	1382306.JNIM01000001_gene2899	4.618e-138	450.0	COG1915@1|root,COG1915@2|Bacteria	2|Bacteria	E	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf,Saccharop_dh_N
SRD1_k127_6153984_5	204669.Acid345_3992	3.727e-26	110.0	COG0215@1|root,COG0215@2|Bacteria,3Y2PW@57723|Acidobacteria,2JHIQ@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRD1_k127_6153984_3	1235799.C818_02516	6.4e-47	175.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,27M94@186928|unclassified Lachnospiraceae	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRD1_k127_6153984_4	429009.Adeg_0401	2.879e-38	153.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,42FTZ@68295|Thermoanaerobacterales	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRD1_k127_6153984_1	264732.Moth_2488	1.695e-77	272.0	COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,248F4@186801|Clostridia,42EMS@68295|Thermoanaerobacterales	186801|Clostridia	S	SMART Nucleotide binding protein, PINc	yacL	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_4,TRAM
SRD1_k127_6153984_0	251221.35212974	2.041e-124	414.0	COG1066@1|root,COG1066@2|Bacteria,1G0A9@1117|Cyanobacteria	1117|Cyanobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
SRD1_k127_6153984_2	861299.J421_4143	3.887e-48	180.0	COG1171@1|root,COG1171@2|Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD1_k127_6154609_2	525904.Tter_0090	3.189e-69	259.0	COG1071@1|root,COG1071@2|Bacteria,2NQC2@2323|unclassified Bacteria	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRD1_k127_6154609_1	926560.KE387023_gene2274	1.031e-109	380.0	COG1249@1|root,COG1249@2|Bacteria,1WJBU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRD1_k127_6154609_0	243164.DET1122	8.261e-182	585.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G8XD@200795|Chloroflexi,34CY9@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRD1_k127_6154609_3	1370121.AUWS01000034_gene4093	4.804e-20	96.0	COG0682@1|root,COG0682@2|Bacteria,2GP8C@201174|Actinobacteria,235FI@1762|Mycobacteriaceae	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT
SRD1_k127_6157033_1	1206731.BAGB01000027_gene2946	3.216e-47	177.0	COG1584@1|root,COG1584@2|Bacteria,2IIIX@201174|Actinobacteria,4G7CY@85025|Nocardiaceae	201174|Actinobacteria	S	GPR1/FUN34/yaaH family	-	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
SRD1_k127_6157033_0	867903.ThesuDRAFT_02120	2.83e-261	820.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes	1239|Firmicutes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRD1_k127_6157033_2	1150864.MILUP08_40336	9.039e-39	157.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4D8SX@85008|Micromonosporales	201174|Actinobacteria	V	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRD1_k127_6157033_3	1123321.KB905815_gene3202	2.239e-36	141.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria	201174|Actinobacteria	L	PFAM HhH-GPD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRD1_k127_6180242_1	222534.KB893725_gene256	2.914e-60	216.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0K@201174|Actinobacteria,4EUPN@85013|Frankiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA8_2	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD1_k127_6180242_0	882.DVU_1606	7.089e-68	252.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria,2M9CJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRD1_k127_6180242_2	1380390.JIAT01000014_gene6100	1.889e-55	212.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4CPB0@84995|Rubrobacteria	84995|Rubrobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRD1_k127_6204249_1	1210884.HG799464_gene11262	5.711e-141	453.0	COG3335@1|root,COG3335@2|Bacteria,2J12Q@203682|Planctomycetes	203682|Planctomycetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
SRD1_k127_6204249_0	886293.Sinac_6159	4.036e-234	728.0	28IU8@1|root,2Z8T0@2|Bacteria,2IXJA@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6215548_3	118166.JH976537_gene616	3.551e-43	176.0	COG1305@1|root,COG1305@2|Bacteria,1FZW2@1117|Cyanobacteria,1H7X1@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Transglutaminase-like superfamily	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
SRD1_k127_6215548_2	1123368.AUIS01000007_gene2717	9.159e-171	567.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,1S6M5@1236|Gammaproteobacteria,2NBV4@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
SRD1_k127_6215548_1	525904.Tter_0415	6.734e-251	788.0	COG0021@1|root,COG0021@2|Bacteria,2NS3T@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRD1_k127_6215548_0	204669.Acid345_2810	1.195e-269	859.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,3Y5VJ@57723|Acidobacteria,2JKZ5@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphoglucose isomerase	-	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRD1_k127_6219417_2	1382306.JNIM01000001_gene4136	1.128e-50	188.0	COG0834@1|root,COG0834@2|Bacteria,2G7BD@200795|Chloroflexi	200795|Chloroflexi	ET	COGs COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRD1_k127_6219417_1	525904.Tter_0904	3.021e-58	213.0	COG0765@1|root,COG0765@2|Bacteria,2NPKZ@2323|unclassified Bacteria	2|Bacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029,ko:K10009	ko02010,map02010	M00234,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1
SRD1_k127_6219417_0	1394178.AWOO02000027_gene5296	1.983e-106	358.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4EHV2@85012|Streptosporangiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	atrC	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRD1_k127_6219417_3	1121428.DESHY_160108___1	0.0001668	44.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,260JW@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
SRD1_k127_6225273_1	373903.Hore_07650	3.758e-80	274.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WAH8@53433|Halanaerobiales	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRD1_k127_6225273_2	273068.TTE1408	1.449e-60	226.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,42EMG@68295|Thermoanaerobacterales	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRD1_k127_6225273_0	246194.CHY_1785	1.934e-100	334.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,42EJV@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRD1_k127_6225273_3	479434.Sthe_1737	2.818e-53	203.0	COG0233@1|root,COG0233@2|Bacteria,2G6FY@200795|Chloroflexi,27Y79@189775|Thermomicrobia	189775|Thermomicrobia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRD1_k127_6225273_4	572477.Alvin_2048	8.88e-10	60.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,1WX0N@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRD1_k127_6252928_2	926569.ANT_20140	1.232e-107	362.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	2|Bacteria	M	PFAM Glycosyl transferase family 2	wcqE	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
SRD1_k127_6252928_6	1231392.OCGS_1680	2.042e-35	147.0	COG0454@1|root,COG0456@2|Bacteria,1NDD2@1224|Proteobacteria	1224|Proteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD1_k127_6252928_5	1485544.JQKP01000001_gene1267	4.991e-42	167.0	COG0500@1|root,COG2226@2|Bacteria,1RFBE@1224|Proteobacteria,2VJY1@28216|Betaproteobacteria,44WE2@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRD1_k127_6252928_0	926569.ANT_20160	3.195e-171	549.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	wecE	GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016769,GO:0019180,GO:0019842,GO:0030170,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901576	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	iE2348C_1286.E2348C_4092,iEC55989_1330.EC55989_4263,iECIAI1_1343.ECIAI1_3978,iECIAI39_1322.ECIAI39_2996,iECO103_1326.ECO103_4373,iECO111_1330.ECO111_4617,iECO26_1355.ECO26_4795,iECUMN_1333.ECUMN_4316,iECW_1372.ECW_m4089,iEKO11_1354.EKO11_4565,iSSON_1240.SSON_3963,iWFL_1372.ECW_m4089	DegT_DnrJ_EryC1
SRD1_k127_6252928_9	1089549.AZUQ01000001_gene565	4.276e-05	56.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4EYK6@85014|Glycomycetales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	menG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRD1_k127_6252928_3	931627.MycrhDRAFT_5099	4.696e-75	276.0	2EE4T@1|root,337ZF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6252928_1	118163.Ple7327_4340	1.735e-145	474.0	COG0463@1|root,COG0463@2|Bacteria,1G4BG@1117|Cyanobacteria,3VJC0@52604|Pleurocapsales	1117|Cyanobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD1_k127_6252928_4	1463825.JNXC01000031_gene1584	1.812e-72	252.0	COG1028@1|root,COG1028@2|Bacteria,2I95F@201174|Actinobacteria,4E4QR@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K14633	ko01057,ko01130,map01057,map01130	-	R09309,R09310	RC02484	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRD1_k127_6252928_7	1206743.BAGM01000109_gene3449	1.302e-33	133.0	COG3193@1|root,COG3193@2|Bacteria,2HNGT@201174|Actinobacteria,4G572@85025|Nocardiaceae	201174|Actinobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
SRD1_k127_6252928_8	1316936.K678_15029	6.912e-09	59.0	COG1514@1|root,COG2755@1|root,COG1514@2|Bacteria,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,2U74E@28211|Alphaproteobacteria,2JS6D@204441|Rhodospirillales	204441|Rhodospirillales	E	GDSL-like Lipase/Acylhydrolase	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
SRD1_k127_6254625_3	316274.Haur_3362	7.323e-107	353.0	COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi,37550@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRD1_k127_6254625_2	1382306.JNIM01000001_gene1299	5.283e-114	379.0	COG1929@1|root,COG1929@2|Bacteria	2|Bacteria	G	organic acid phosphorylation	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRD1_k127_6254625_5	1121422.AUMW01000024_gene240	8.126e-22	105.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_6254625_1	1128421.JAGA01000002_gene682	2.388e-139	449.0	COG0214@1|root,COG0214@2|Bacteria,2NNZ6@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRD1_k127_6254625_4	1440053.JOEI01000036_gene6558	7.223e-56	204.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRD1_k127_6254625_0	309801.trd_0202	1.111e-140	457.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi,27Y49@189775|Thermomicrobia	189775|Thermomicrobia	S	R3H domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA,R3H
SRD1_k127_6266006_1	1054213.HMPREF9946_04870	2.992e-92	316.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRD1_k127_6266006_0	867903.ThesuDRAFT_01054	2.652e-114	375.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia	186801|Clostridia	IQ	reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD1_k127_6266006_2	1159488.SEQMU2_01020	1.732e-22	108.0	COG1388@1|root,COG3942@1|root,COG1388@2|Bacteria,COG3942@2|Bacteria,1V8WM@1239|Firmicutes,4I27S@91061|Bacilli,4GX44@90964|Staphylococcaceae	91061|Bacilli	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,LysM
SRD1_k127_6266006_3	1151061.CAJY01000036_gene1478	4.211e-11	70.0	COG0477@1|root,COG2814@2|Bacteria,2HBIW@201174|Actinobacteria	201174|Actinobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD1_k127_6266283_2	1120949.KB903330_gene9151	1.512e-97	333.0	COG0683@1|root,COG0683@2|Bacteria,2IEFV@201174|Actinobacteria,4DK6Z@85008|Micromonosporales	201174|Actinobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRD1_k127_6266283_0	1120949.KB903330_gene9150	1.617e-103	345.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,4DM3Q@85008|Micromonosporales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD1_k127_6266283_1	1120949.KB903330_gene9149	1.045e-101	342.0	COG4177@1|root,COG4177@2|Bacteria,2I93C@201174|Actinobacteria,4DJPW@85008|Micromonosporales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD1_k127_6266283_3	1121439.dsat_1286	2.512e-33	135.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,42NNW@68525|delta/epsilon subdivisions,2WMWA@28221|Deltaproteobacteria,2MA46@213115|Desulfovibrionales	28221|Deltaproteobacteria	GM	pfam abc	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
SRD1_k127_6275828_2	1128421.JAGA01000002_gene202	2.882e-50	186.0	COG1307@1|root,COG1307@2|Bacteria,2NQTE@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised protein, DegV family COG1307	degV	-	-	-	-	-	-	-	-	-	-	-	DegV
SRD1_k127_6275828_3	1382306.JNIM01000001_gene2482	5.66e-49	184.0	COG3662@1|root,COG3662@2|Bacteria,2G8VS@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRD1_k127_6275828_1	1449355.JQNR01000004_gene1668	2.564e-57	207.0	COG4280@1|root,COG4280@2|Bacteria,2GN58@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
SRD1_k127_6275828_0	309801.trd_0084	2.053e-167	549.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi,27XT4@189775|Thermomicrobia	189775|Thermomicrobia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRD1_k127_6275828_4	709986.Deima_0127	1.226e-36	144.0	COG3885@1|root,COG3885@2|Bacteria	2|Bacteria	S	ferrous iron binding	amrA	-	-	ko:K06990,ko:K15755	ko00621,ko01100,ko01120,ko01220,map00621,map01100,map01120,map01220	M00544	R05415	RC01306	br01602,ko00000,ko00001,ko00002,ko01000,ko04812	-	-	-	AMMECR1,LigB
SRD1_k127_6289678_0	1121918.ARWE01000001_gene3110	9.727e-136	459.0	COG3387@1|root,COG3387@2|Bacteria,1MYVI@1224|Proteobacteria,42YST@68525|delta/epsilon subdivisions,2WURK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Glucodextranase, domain N	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glucodextran_N,Glyco_hydro_15
SRD1_k127_6289678_1	1313265.JNIE01000008_gene73	4.545e-49	178.0	COG0476@1|root,COG0476@2|Bacteria,2G4P8@200783|Aquificae	200783|Aquificae	H	PFAM UBA THIF-type NAD FAD binding protein	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
SRD1_k127_6322225_0	479434.Sthe_1183	3.756e-154	502.0	COG4262@1|root,COG4262@2|Bacteria,2G5YS@200795|Chloroflexi	200795|Chloroflexi	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRD1_k127_6324341_1	1246995.AFR_34865	1.064e-51	188.0	COG0122@1|root,COG0122@2|Bacteria,2GP69@201174|Actinobacteria,4D9BH@85008|Micromonosporales	201174|Actinobacteria	L	3-methyladenine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6324341_0	861299.J421_3665	8.87e-188	603.0	COG1164@1|root,COG1164@2|Bacteria,1ZTDD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SRD1_k127_6324341_2	1297742.A176_03908	1.916e-44	173.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,42USD@68525|delta/epsilon subdivisions,2WQCM@28221|Deltaproteobacteria,2YXGM@29|Myxococcales	28221|Deltaproteobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRD1_k127_6324341_3	324602.Caur_0250	7.83e-21	94.0	COG1013@1|root,COG1013@2|Bacteria,2G679@200795|Chloroflexi,374ZH@32061|Chloroflexia	32061|Chloroflexia	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRD1_k127_6326650_2	398767.Glov_0095	1.162e-16	90.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WIJM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD1_k127_6326650_1	479434.Sthe_1406	3.845e-31	130.0	COG1051@1|root,COG1051@2|Bacteria,2G77J@200795|Chloroflexi,27YGM@189775|Thermomicrobia	189775|Thermomicrobia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRD1_k127_6326650_0	861299.J421_2398	2.697e-38	149.0	COG0745@1|root,COG2199@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1ZT7F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
SRD1_k127_6331114_3	1206733.BAGC01000041_gene1874	7.858e-56	202.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4FXF4@85025|Nocardiaceae	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_6331114_2	880073.Calab_0865	2.869e-57	209.0	COG0491@1|root,COG0491@2|Bacteria,2NPRD@2323|unclassified Bacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	ytnP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRD1_k127_6331114_5	1463934.JOCF01000023_gene6163	5.257e-39	165.0	COG0596@1|root,COG0596@2|Bacteria,2GNBX@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the peptidase S33 family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRD1_k127_6331114_1	637389.Acaty_c1511	1.129e-129	431.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,2NBU3@225057|Acidithiobacillales	225057|Acidithiobacillales	O	MCM2/3/5 family	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRD1_k127_6331114_4	290397.Adeh_2700	1.93e-55	205.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,2YVFF@29|Myxococcales	28221|Deltaproteobacteria	LU	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
SRD1_k127_6331114_0	485913.Krac_10925	1.234e-207	670.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi	200795|Chloroflexi	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRD1_k127_6390817_0	234267.Acid_5121	7.858e-219	691.0	COG0480@1|root,COG0480@2|Bacteria,3Y2YX@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRD1_k127_6402364_4	390989.JOEG01000019_gene5909	6.684e-20	90.0	COG0262@1|root,COG0262@2|Bacteria,2GMZV@201174|Actinobacteria,4DE9F@85008|Micromonosporales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRD1_k127_6402364_5	1045855.DSC_11355	4.324e-15	80.0	2EGCD@1|root,33A46@2|Bacteria,1NMIX@1224|Proteobacteria,1SIUN@1236|Gammaproteobacteria,1X8EM@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
SRD1_k127_6402364_6	84531.JMTZ01000086_gene1373	3.768e-11	68.0	2EGCD@1|root,33A46@2|Bacteria,1NMIX@1224|Proteobacteria,1SIUN@1236|Gammaproteobacteria,1X8EM@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
SRD1_k127_6402364_3	1283299.AUKG01000002_gene4309	7.094e-64	231.0	COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria,4CR72@84995|Rubrobacteria	84995|Rubrobacteria	M	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Choline_kinase
SRD1_k127_6402364_1	926560.KE387023_gene1931	6.035e-157	512.0	COG0160@1|root,COG0160@2|Bacteria,1WIP2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_6402364_0	469383.Cwoe_1552	5.951e-193	633.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CPEC@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD1_k127_6402364_2	1380390.JIAT01000011_gene2578	3.876e-95	316.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
SRD1_k127_6419590_0	1408224.SAMCCGM7_c5115	2.701e-82	278.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,4BB7Y@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	-	GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009448,GO:0009450,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0032787,GO:0034641,GO:0042133,GO:0042135,GO:0042402,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0072329,GO:0097164,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.16,1.2.1.20,1.2.1.24,1.2.1.79	ko:K00135,ko:K08324	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD1_k127_6419590_2	525904.Tter_0417	1.398e-17	90.0	COG1437@1|root,COG1437@2|Bacteria,2NRYX@2323|unclassified Bacteria	2|Bacteria	F	CYTH domain	cyaB	-	4.6.1.1	ko:K01768,ko:K05873	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
SRD1_k127_6419590_1	330084.JNYZ01000032_gene5549	3.933e-44	164.0	COG1832@1|root,COG1832@2|Bacteria,2IHSP@201174|Actinobacteria,4E51X@85010|Pseudonocardiales	201174|Actinobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRD1_k127_6424464_0	644283.Micau_6111	4.797e-64	240.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria,4DAHT@85008|Micromonosporales	201174|Actinobacteria	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87,PrgI
SRD1_k127_6441587_3	525904.Tter_0673	1.45e-12	69.0	COG0568@1|root,COG0568@2|Bacteria,2NNY9@2323|unclassified Bacteria	2|Bacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD1_k127_6441587_1	525904.Tter_0383	1.796e-22	104.0	COG0071@1|root,COG0071@2|Bacteria,2NPXZ@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRD1_k127_6441587_0	290397.Adeh_1433	2.103e-35	139.0	COG4747@1|root,COG4747@2|Bacteria,1RDCG@1224|Proteobacteria,42RTD@68525|delta/epsilon subdivisions,2WNC2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
SRD1_k127_6441587_2	1121946.AUAX01000005_gene5502	1.844e-18	87.0	COG1309@1|root,COG1309@2|Bacteria,2ISE5@201174|Actinobacteria,4DM6H@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD1_k127_6481721_0	926569.ANT_13300	5.023e-27	130.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
SRD1_k127_6512822_0	502025.Hoch_2000	1.081e-308	964.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2_2
SRD1_k127_6512822_2	502025.Hoch_2001	8.994e-65	236.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,4309M@68525|delta/epsilon subdivisions,2WV9K@28221|Deltaproteobacteria,2Z3A1@29|Myxococcales	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
SRD1_k127_6512822_1	502025.Hoch_2002	1.228e-65	229.0	COG1319@1|root,COG1319@2|Bacteria,1PG5C@1224|Proteobacteria,43EJH@68525|delta/epsilon subdivisions,2X9UI@28221|Deltaproteobacteria,2Z2GS@29|Myxococcales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRD1_k127_6522150_2	1463861.JNXE01000032_gene1455	3.67e-49	192.0	COG1477@1|root,COG1477@2|Bacteria,2H74Y@201174|Actinobacteria	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRD1_k127_6522150_1	1122138.AQUZ01000008_gene3640	7.935e-79	273.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4DNG2@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRD1_k127_6522150_4	1463900.JOIX01000004_gene4897	1.473e-23	113.0	COG0662@1|root,COG0662@2|Bacteria,2IHNU@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD1_k127_6522150_3	1122604.JONR01000026_gene3000	3.892e-43	162.0	COG0393@1|root,COG0393@2|Bacteria,1N2F5@1224|Proteobacteria,1SDQC@1236|Gammaproteobacteria,1X7NT@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
SRD1_k127_6522150_5	646529.Desaci_2611	1.617e-06	57.0	2EISG@1|root,33CHT@2|Bacteria,1VMS2@1239|Firmicutes,24RY6@186801|Clostridia,266HS@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6522150_0	1306406.ASHX01000002_gene5137	6.046e-138	445.0	COG3011@1|root,COG3011@2|Bacteria,2GMSU@201174|Actinobacteria	201174|Actinobacteria	S	Lipase maturation factor	LMF	-	-	-	-	-	-	-	-	-	-	-	LMF1
SRD1_k127_6531823_0	644966.Tmar_1991	3.892e-113	376.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,3WCD3@538999|Clostridiales incertae sedis	186801|Clostridia	H	Riboflavin biosynthesis protein RibD	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRD1_k127_6531823_1	1232427.CAVS020000026_gene1170	5.518e-23	103.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,22M8W@1653|Corynebacteriaceae	201174|Actinobacteria	H	Riboflavin synthase	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRD1_k127_6554934_2	1157640.AQWO01000008_gene4072	4.973e-46	173.0	COG0596@1|root,COG0596@2|Bacteria,2GJYS@201174|Actinobacteria	201174|Actinobacteria	NU	Alpha beta hydrolase	slpD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRD1_k127_6554934_0	561175.KB894093_gene4240	1.506e-119	400.0	COG0596@1|root,COG0596@2|Bacteria,2GJYS@201174|Actinobacteria,4EFG6@85012|Streptosporangiales	201174|Actinobacteria	S	TAP-like protein	slpD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRD1_k127_6554934_1	639283.Snov_2721	4.825e-53	191.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,3EXXI@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRD1_k127_6584434_3	234267.Acid_3697	5.736e-05	46.0	COG1287@1|root,COG1287@2|Bacteria,3Y5FJ@57723|Acidobacteria	57723|Acidobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6584434_2	926569.ANT_18400	9.395e-30	136.0	COG1287@1|root,COG1287@2|Bacteria,2G785@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6584434_0	926550.CLDAP_23270	1.532e-64	239.0	COG0463@1|root,COG0463@2|Bacteria,2GBP0@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRD1_k127_6584434_1	886293.Sinac_4732	1.153e-61	220.0	COG1215@1|root,COG1215@2|Bacteria,2J0E2@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD1_k127_6597473_4	1267535.KB906767_gene1648	1.013e-17	87.0	COG5646@1|root,COG5646@2|Bacteria,3Y5GZ@57723|Acidobacteria,2JNWJ@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRD1_k127_6597473_1	404589.Anae109_3495	2.117e-53	196.0	2CK59@1|root,32VV2@2|Bacteria,1P616@1224|Proteobacteria,4329Y@68525|delta/epsilon subdivisions,2X772@28221|Deltaproteobacteria,2YVDY@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6597473_0	1300345.LF41_793	6.257e-69	240.0	COG0262@1|root,COG0262@2|Bacteria,1RH02@1224|Proteobacteria,1S2UN@1236|Gammaproteobacteria,1XAW8@135614|Xanthomonadales	135614|Xanthomonadales	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRD1_k127_6597473_2	493475.GARC_4063	2.95e-28	113.0	COG0346@1|root,COG0346@2|Bacteria,1N08M@1224|Proteobacteria,1SE7M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6610639_0	351607.Acel_1545	1.801e-98	334.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4ERWA@85013|Frankiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpE	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
SRD1_k127_6610639_3	405948.SACE_2451	1.689e-16	85.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria,4ECNY@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRD1_k127_6610639_5	479434.Sthe_2622	3.567e-07	59.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
SRD1_k127_6610639_1	909663.KI867150_gene2841	1.835e-29	126.0	COG0662@1|root,COG0662@2|Bacteria,1RJ7D@1224|Proteobacteria,431RV@68525|delta/epsilon subdivisions,2WWFG@28221|Deltaproteobacteria,2MS3I@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD1_k127_6610639_4	1429046.RR21198_3908	1.332e-10	66.0	2E9P6@1|root,333VK@2|Bacteria,2GVEJ@201174|Actinobacteria,4G23P@85025|Nocardiaceae	201174|Actinobacteria	S	SPW repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPW
SRD1_k127_6610639_2	1234664.AMRO01000080_gene1196	2.436e-27	122.0	COG0791@1|root,COG0791@2|Bacteria,1TSZ0@1239|Firmicutes,4HBUM@91061|Bacilli,1WG74@129337|Geobacillus	91061|Bacilli	M	NlpC/P60 family	ykfC	-	3.4.14.13	ko:K20742	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	NLPC_P60
SRD1_k127_6644224_6	479433.Caci_1103	3.638e-74	267.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria	201174|Actinobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N,PTS-HPr
SRD1_k127_6644224_7	479432.Sros_3047	1.342e-58	210.0	COG1461@1|root,COG1461@2|Bacteria,2HEQ9@201174|Actinobacteria,4EJE3@85012|Streptosporangiales	201174|Actinobacteria	S	Dak2	dhaL	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
SRD1_k127_6644224_3	1043205.AFYF01000053_gene3096	1.873e-136	446.0	COG2376@1|root,COG2376@2|Bacteria,2GJV9@201174|Actinobacteria,4FGRD@85021|Intrasporangiaceae	201174|Actinobacteria	G	Dak1 domain	dhaK	-	2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	M00344	R01011,R01012,R01059	RC00002,RC00015,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Dak1
SRD1_k127_6644224_9	110319.CF8_3307	4.498e-56	206.0	COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria,4DPG7@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440,ko:K06188,ko:K09874	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.12,1.A.8.2	-	-	MIP
SRD1_k127_6644224_1	765420.OSCT_0356	1.047e-164	534.0	COG0119@1|root,COG0119@2|Bacteria,2G5KT@200795|Chloroflexi,3758Q@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRD1_k127_6644224_0	471852.Tcur_4129	3.125e-311	976.0	COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria,4EHTY@85012|Streptosporangiales	201174|Actinobacteria	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
SRD1_k127_6644224_4	321332.CYB_1130	3.588e-88	301.0	COG3437@1|root,COG3437@2|Bacteria,1G2ZH@1117|Cyanobacteria,1H05S@1129|Synechococcus	1117|Cyanobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
SRD1_k127_6644224_10	1463856.JOHY01000008_gene853	1.017e-05	58.0	COG0457@1|root,COG0457@2|Bacteria,2INUN@201174|Actinobacteria	201174|Actinobacteria	G	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,NB-ARC,TPR_10,TPR_12,TPR_7
SRD1_k127_6644224_8	485913.Krac_8323	1.412e-56	222.0	COG5002@1|root,COG5002@2|Bacteria,2G8WY@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
SRD1_k127_6644224_2	926550.CLDAP_18710	1.639e-144	467.0	COG4638@1|root,COG4638@2|Bacteria,2G720@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.14.12.19,1.14.15.7	ko:K00479,ko:K00499,ko:K05708	ko00260,ko00360,ko01120,ko01220,map00260,map00360,map01120,map01220	M00545	R06782,R06783,R07409	RC00087,RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
SRD1_k127_6644224_5	251221.35210936	9.669e-88	309.0	COG1574@1|root,COG1574@2|Bacteria,1G40U@1117|Cyanobacteria	1117|Cyanobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRD1_k127_6686587_1	1123239.KB898625_gene271	2.008e-50	181.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HC2S@91061|Bacilli	91061|Bacilli	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_6686587_0	986075.CathTA2_1193	3.657e-90	304.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HC2S@91061|Bacilli	91061|Bacilli	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_6686587_2	1118054.CAGW01000014_gene335	6.177e-18	90.0	COG2030@1|root,COG2030@2|Bacteria,1VCFH@1239|Firmicutes	1239|Firmicutes	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRD1_k127_6686587_3	714083.JH370377_gene362	2.374e-07	58.0	COG2030@1|root,COG2030@2|Bacteria,2GMVC@201174|Actinobacteria,4FNUQ@85023|Microbacteriaceae	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	hadA	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRD1_k127_66909_1	756499.Desde_1370	1.153e-88	307.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,25ZZP@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRD1_k127_66909_0	264732.Moth_2048	3.411e-101	340.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,42F8R@68295|Thermoanaerobacterales	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
SRD1_k127_6694412_0	309801.trd_1505	2.273e-53	194.0	COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi,27XSH@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRD1_k127_6694412_2	429009.Adeg_2148	9.084e-32	132.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,42G7M@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Single-stranded nucleic acid binding R3H	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRD1_k127_6694412_1	246194.CHY_0004	1.631e-32	138.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,42G81@68295|Thermoanaerobacterales	186801|Clostridia	U	PFAM 60 kDa inner membrane insertion protein	oxaA	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRD1_k127_6694412_3	321332.CYB_0560	9.24e-25	106.0	COG0759@1|root,COG0759@2|Bacteria,1G90B@1117|Cyanobacteria,1H14U@1129|Synechococcus	1117|Cyanobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRD1_k127_6694412_5	1096546.WYO_0275	3.364e-11	69.0	COG0594@1|root,COG0594@2|Bacteria,1Q41P@1224|Proteobacteria,2VAIV@28211|Alphaproteobacteria,1JW2N@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRD1_k127_6694412_6	429009.Adeg_2152	1.806e-09	60.0	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,42HF3@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRD1_k127_6694412_4	545693.BMQ_0001	6.846e-13	74.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,1ZBKI@1386|Bacillus	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRD1_k127_6757285_0	861299.J421_0455	1.985e-240	756.0	COG0841@1|root,COG0841@2|Bacteria,1ZUFU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRD1_k127_6759461_3	477974.Daud_0190	3.456e-47	176.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,2602K@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRD1_k127_6759461_2	329726.AM1_0668	2.348e-49	190.0	COG0457@1|root,COG1994@1|root,COG0457@2|Bacteria,COG1994@2|Bacteria,1G1EH@1117|Cyanobacteria	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
SRD1_k127_6759461_4	1000569.HMPREF1040_0714	2.818e-19	102.0	COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4H52Z@909932|Negativicutes	909932|Negativicutes	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
SRD1_k127_6759461_0	760568.Desku_1651	1.372e-123	419.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,260WY@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
SRD1_k127_6759461_1	479434.Sthe_2201	4.326e-59	213.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,27XM3@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRD1_k127_6822455_2	1449347.JQLN01000007_gene1837	2.5e-81	290.0	COG1290@1|root,COG1290@2|Bacteria,2GK58@201174|Actinobacteria	201174|Actinobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_N_2
SRD1_k127_6822455_3	525909.Afer_1523	1.512e-74	257.0	COG1290@1|root,COG1290@2|Bacteria,2GK58@201174|Actinobacteria,4CNNI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6822455_4	1121877.JQKF01000039_gene1843	0.0003547	46.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_B
SRD1_k127_6822455_1	1120950.KB892761_gene5808	7.997e-122	402.0	COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4DQ5W@85009|Propionibacteriales	201174|Actinobacteria	C	Acetokinase family	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
SRD1_k127_6822455_0	1394178.AWOO02000030_gene4705	2.144e-146	466.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4EGX0@85012|Streptosporangiales	201174|Actinobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRD1_k127_6868379_3	204669.Acid345_4444	7.358e-36	136.0	COG0025@1|root,COG0025@2|Bacteria	2|Bacteria	P	sodium:proton antiporter activity	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,zf-UBP
SRD1_k127_6868379_1	324602.Caur_2454	1.219e-54	197.0	COG0262@1|root,COG0262@2|Bacteria,2G8M0@200795|Chloroflexi,377EH@32061|Chloroflexia	32061|Chloroflexia	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRD1_k127_6868379_0	543632.JOJL01000039_gene1638	4.122e-209	668.0	COG0465@1|root,COG0465@2|Bacteria,2H5KC@201174|Actinobacteria,4DM46@85008|Micromonosporales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRD1_k127_6868379_5	1122939.ATUD01000007_gene1943	6.021e-26	111.0	COG3695@1|root,COG3695@2|Bacteria,2HRG8@201174|Actinobacteria,4CTFC@84995|Rubrobacteria	84995|Rubrobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
SRD1_k127_6868379_4	1386089.N865_06430	1.913e-32	136.0	29XZ9@1|root,30JRZ@2|Bacteria,2GTWZ@201174|Actinobacteria,4FJEC@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_6868379_2	1232410.KI421421_gene3566	3.038e-42	170.0	COG1524@1|root,COG1524@2|Bacteria,1QX9K@1224|Proteobacteria	1224|Proteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRD1_k127_68697_0	118166.JH976537_gene1816	1.137e-90	323.0	COG0744@1|root,COG0744@2|Bacteria,1G1XF@1117|Cyanobacteria,1H8WS@1150|Oscillatoriales	1117|Cyanobacteria	M	Penicillin-binding protein, 1A family	mrcB	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRD1_k127_689889_1	926561.KB900617_gene2258	3.632e-98	343.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,3WA7K@53433|Halanaerobiales	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
SRD1_k127_689889_0	1382356.JQMP01000003_gene2232	7.857e-126	413.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi,27XY6@189775|Thermomicrobia	189775|Thermomicrobia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRD1_k127_6905849_0	485913.Krac_11079	9.555e-73	259.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2G65W@200795|Chloroflexi	200795|Chloroflexi	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRD1_k127_6954981_0	1379270.AUXF01000001_gene2325	6.305e-282	895.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1ZSQA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Conserved region in glutamate synthase	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRD1_k127_6958485_1	1380347.JNII01000006_gene1593	1.07e-109	376.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRD1_k127_6958485_7	1382306.JNIM01000001_gene3957	1.881e-27	116.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRD1_k127_6958485_4	1382306.JNIM01000001_gene4085	7.083e-67	239.0	COG0407@1|root,COG0407@2|Bacteria,2G6BE@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRD1_k127_6958485_0	479434.Sthe_0985	1.795e-153	498.0	COG0277@1|root,COG0277@2|Bacteria,2G5TM@200795|Chloroflexi,27XF8@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRD1_k127_6958485_5	326427.Cagg_1892	1.064e-57	218.0	COG0277@1|root,COG0277@2|Bacteria,2G6FW@200795|Chloroflexi,376EU@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD linked oxidase domain protein	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
SRD1_k127_6958485_3	357808.RoseRS_3607	1.007e-97	332.0	COG0247@1|root,COG0247@2|Bacteria,2G5V8@200795|Chloroflexi,37729@32061|Chloroflexia	32061|Chloroflexia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
SRD1_k127_6958485_2	1382306.JNIM01000001_gene1145	4.77e-99	333.0	COG2309@1|root,COG2309@2|Bacteria	2|Bacteria	E	aminopeptidase activity	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
SRD1_k127_6958485_6	1382306.JNIM01000001_gene897	4.686e-43	167.0	COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRD1_k127_6958485_8	1382356.JQMP01000004_gene415	3.033e-14	86.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,27Y7S@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
SRD1_k127_6992137_0	1382306.JNIM01000001_gene1605	3.593e-47	180.0	COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi	200795|Chloroflexi	E	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRD1_k127_6992137_1	1206720.BAFQ01000135_gene3382	3.247e-46	169.0	COG2876@1|root,COG2876@2|Bacteria,2I3UA@201174|Actinobacteria	201174|Actinobacteria	E	PFAM DAHP synthetase I	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRD1_k127_6994730_0	58123.JOFJ01000030_gene1191	6.712e-122	406.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4EG41@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme	alkK	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD1_k127_6994730_4	1382306.JNIM01000001_gene4122	2.864e-42	165.0	COG0613@1|root,COG0613@2|Bacteria,2G74N@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
SRD1_k127_6994730_5	1146883.BLASA_1782	4e-29	131.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
SRD1_k127_6994730_2	1128421.JAGA01000004_gene2534	5.096e-68	250.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRD1_k127_6994730_6	935866.JAER01000046_gene543	8.823e-20	97.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria,4DQEU@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_6994730_3	1123354.AUDR01000013_gene805	4.155e-52	208.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,2WFNY@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Ornithine cyclodeaminase mu-crystallin	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRD1_k127_6994730_1	935948.KE386495_gene1409	8.784e-109	364.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,42EN4@68295|Thermoanaerobacterales	186801|Clostridia	E	homoserine dehydrogenase NAD-binding	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SRD1_k127_7014620_3	309801.trd_0869	7.002e-59	217.0	COG5282@1|root,COG5282@2|Bacteria,2G800@200795|Chloroflexi,27XTJ@189775|Thermomicrobia	189775|Thermomicrobia	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRD1_k127_7014620_5	673860.AciM339_1354	1.076e-28	120.0	arCOG12220@1|root,arCOG12220@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7014620_2	316274.Haur_2614	3.451e-74	257.0	COG1028@1|root,COG1028@2|Bacteria,2G5KB@200795|Chloroflexi,3759E@32061|Chloroflexia	316274.Haur_2614|-	IQ	short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7014620_4	1380390.JIAT01000010_gene4277	4.673e-58	220.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4CQ6C@84995|Rubrobacteria	84995|Rubrobacteria	GM	Epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRD1_k127_7014620_1	526225.Gobs_3881	2.504e-86	297.0	COG1893@1|root,COG1893@2|Bacteria,2I3AM@201174|Actinobacteria,4ETFG@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRD1_k127_7014620_0	1122611.KB904018_gene6998	9.777e-123	424.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,4EH6A@85012|Streptosporangiales	201174|Actinobacteria	L	DSHCT	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
SRD1_k127_7014620_6	525904.Tter_1743	2.719e-15	80.0	COG1550@1|root,COG1550@2|Bacteria	2|Bacteria	H	Protein conserved in bacteria	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRD1_k127_7022302_2	946483.Cenrod_1616	3.691e-06	51.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,4ABRN@80864|Comamonadaceae	28216|Betaproteobacteria	E	glutamate synthase, alpha subunit domain protein	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRD1_k127_7022302_1	306281.AJLK01000017_gene3766	6.421e-07	59.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1JK6S@1189|Stigonemataceae	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
SRD1_k127_7022302_0	1128421.JAGA01000003_gene3369	1.702e-55	202.0	COG0673@1|root,COG0673@2|Bacteria,2NP86@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRD1_k127_7027395_1	485913.Krac_2984	3.146e-203	646.0	COG1231@1|root,COG1231@2|Bacteria,2G942@200795|Chloroflexi	200795|Chloroflexi	E	PFAM amine oxidase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRD1_k127_7027395_0	1463934.JOCF01000015_gene564	7.036e-224	708.0	COG4409@1|root,COG4409@2|Bacteria,2H1PD@201174|Actinobacteria	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7028643_2	1121324.CLIT_23c00500	5.775e-117	387.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia	186801|Clostridia	U	Type II IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRD1_k127_7028643_1	15368.BRADI3G18990.1	2.96e-120	396.0	COG0458@1|root,KOG0370@2759|Eukaryota,37MJ1@33090|Viridiplantae,3GGQ1@35493|Streptophyta,3KQ6H@4447|Liliopsida,3I5GI@38820|Poales	35493|Streptophyta	EF	Belongs to the ATCase OTCase family	PYRB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009267,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009987,GO:0009991,GO:0016036,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0034654,GO:0042594,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRD1_k127_7028643_3	1122175.ATXU01000008_gene245	6.574e-53	191.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,4FNED@85023|Microbacteriaceae	201174|Actinobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRD1_k127_7028643_4	1163409.UUA_09246	1.476e-21	111.0	2EHAS@1|root,33B2M@2|Bacteria,1NZNX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7028643_0	309801.trd_0212	1.432e-192	635.0	COG0458@1|root,COG0458@2|Bacteria,2G5NX@200795|Chloroflexi,27XRT@189775|Thermomicrobia	189775|Thermomicrobia	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRD1_k127_7033667_1	1151061.CAJY01000016_gene565	7.959e-37	151.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRD1_k127_7033667_0	671143.DAMO_2385	3.303e-100	340.0	COG0489@1|root,COG0489@2|Bacteria,2NNX1@2323|unclassified Bacteria	2|Bacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRD1_k127_7033667_2	371731.Rsw2DRAFT_3293	3.582e-32	134.0	COG0095@1|root,COG0095@2|Bacteria,1RDZE@1224|Proteobacteria	1224|Proteobacteria	H	PFAM biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
SRD1_k127_7037984_4	591159.ACEZ01000206_gene7046	2.562e-54	196.0	COG1247@1|root,COG1247@2|Bacteria,2II0A@201174|Actinobacteria	201174|Actinobacteria	M	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7037984_9	649831.L083_7979	2.423e-29	129.0	COG0457@1|root,COG0457@2|Bacteria,2I9X6@201174|Actinobacteria,4DEK8@85008|Micromonosporales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4034
SRD1_k127_7037984_10	1121272.KB903249_gene1252	8.112e-29	129.0	COG2365@1|root,COG2365@2|Bacteria,2INRM@201174|Actinobacteria,4DF56@85008|Micromonosporales	201174|Actinobacteria	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
SRD1_k127_7037984_7	760568.Desku_3022	1.99e-42	159.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,261YG@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRD1_k127_7037984_5	373903.Hore_02460	2.15e-46	172.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,3WAPJ@53433|Halanaerobiales	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRD1_k127_7037984_3	555079.Toce_0152	3.743e-58	210.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,42FMH@68295|Thermoanaerobacterales	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRD1_k127_7037984_8	937777.Deipe_3065	1.313e-30	124.0	COG0203@1|root,COG0203@2|Bacteria,1WK7W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRD1_k127_7037984_0	1051632.TPY_0350	2.559e-104	347.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3WCF9@538999|Clostridiales incertae sedis	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRD1_k127_7037984_1	349161.Dred_0242	2.386e-76	262.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,260U9@186807|Peptococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRD1_k127_7037984_2	189426.PODO_27675	3.529e-58	207.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,26WQK@186822|Paenibacillaceae	91061|Bacilli	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRD1_k127_7037984_6	485913.Krac_12504	2.084e-43	161.0	COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi	200795|Chloroflexi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRD1_k127_7038646_1	644283.Micau_3083	3.251e-88	299.0	COG3217@1|root,COG3217@2|Bacteria,2GPWY@201174|Actinobacteria,4DCH4@85008|Micromonosporales	201174|Actinobacteria	S	MOSC domain protein beta barrel domain protein	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRD1_k127_7038646_4	1380390.JIAT01000009_gene661	1.236e-45	174.0	COG3629@1|root,COG3629@2|Bacteria,2IBMM@201174|Actinobacteria,4CTN8@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRD1_k127_7038646_10	1173028.ANKO01000017_gene206	0.0002362	49.0	COG1359@1|root,COG1359@2|Bacteria,1G94C@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Antibiotic biosynthesis monooxygenase	-	GO:0003674,GO:0003824	-	-	-	-	-	-	-	-	-	-	ABM
SRD1_k127_7038646_2	710685.MycrhN_1614	5.759e-70	246.0	COG1011@1|root,COG1011@2|Bacteria,2HHHH@201174|Actinobacteria,2341D@1762|Mycobacteriaceae	201174|Actinobacteria	S	haloacid dehalogenase	dehII	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
SRD1_k127_7038646_0	47716.JOFH01000019_gene4945	1.508e-154	496.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_7038646_5	405948.SACE_5368	1.91e-38	154.0	COG0748@1|root,COG0748@2|Bacteria,2I63J@201174|Actinobacteria,4EE4G@85010|Pseudonocardiales	201174|Actinobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRD1_k127_7038646_6	479431.Namu_2557	9.249e-35	145.0	COG1765@1|root,COG1765@2|Bacteria,2IFY4@201174|Actinobacteria,4ET1W@85013|Frankiales	201174|Actinobacteria	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRD1_k127_7038646_3	710696.Intca_2822	1.181e-51	196.0	COG2210@1|root,COG2210@2|Bacteria,2IGW8@201174|Actinobacteria	201174|Actinobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRD1_k127_7038646_8	319225.Plut_0033	1.408e-19	90.0	COG0425@1|root,COG0425@2|Bacteria,1FE4M@1090|Chlorobi	1090|Chlorobi	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
SRD1_k127_7038646_7	351607.Acel_0523	2.291e-30	121.0	COG0446@1|root,COG0446@2|Bacteria,2GRTN@201174|Actinobacteria,4ESWT@85013|Frankiales	201174|Actinobacteria	S	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DsrC,Pyr_redox_2
SRD1_k127_7045693_0	1254432.SCE1572_49820	3.958e-122	411.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42M8D@68525|delta/epsilon subdivisions,2WJ6E@28221|Deltaproteobacteria,2YWFY@29|Myxococcales	28221|Deltaproteobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C,Fer2_BFD
SRD1_k127_7046631_0	298655.KI912266_gene2030	1.357e-149	486.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4ERKP@85013|Frankiales	201174|Actinobacteria	H	PFAM Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD1_k127_7046631_4	1120948.KB903218_gene2262	1.092e-89	314.0	COG2141@1|root,COG2141@2|Bacteria,2GMMJ@201174|Actinobacteria,4E2MJ@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD1_k127_7046631_8	1121472.AQWN01000006_gene1709	2.792e-40	158.0	COG3290@1|root,COG3437@1|root,COG3290@2|Bacteria,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24Y6H@186801|Clostridia,267AY@186807|Peptococcaceae	186801|Clostridia	T	diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,HD,HD_5,PAS,PAS_3,PAS_4,PAS_9,SBP_bac_3,dCache_1
SRD1_k127_7046631_9	485913.Krac_4003	9.405e-24	108.0	2E4G6@1|root,335WF@2|Bacteria,2G9R2@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7046631_3	1380390.JIAT01000011_gene2478	9.138e-93	315.0	COG1018@1|root,COG1018@2|Bacteria,2I28S@201174|Actinobacteria,4CPW9@84995|Rubrobacteria	84995|Rubrobacteria	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
SRD1_k127_7046631_1	479434.Sthe_0341	1.83e-98	325.0	COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRD1_k127_7046631_6	1048834.TC41_0467	6.147e-70	261.0	COG1686@1|root,COG1686@2|Bacteria,1VZJP@1239|Firmicutes	1239|Firmicutes	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
SRD1_k127_7046631_2	485913.Krac_1451	2.722e-98	328.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC-3 protein	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRD1_k127_7046631_7	104623.Ser39006_00643	2.915e-50	203.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,1RPJT@1236|Gammaproteobacteria,404XZ@613|Serratia	1236|Gammaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02074	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
SRD1_k127_7046631_5	485913.Krac_4091	4.468e-85	291.0	COG0803@1|root,COG0803@2|Bacteria,2G8F6@200795|Chloroflexi	200795|Chloroflexi	P	PFAM periplasmic solute binding protein	-	-	-	ko:K02077,ko:K09815,ko:K09818,ko:K11707	ko02010,map02010	M00242,M00243,M00244,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SRD1_k127_7046631_10	1231241.Mc24_02733	1.118e-15	85.0	COG0735@1|root,COG0735@2|Bacteria,2GD8Q@200918|Thermotogae	200918|Thermotogae	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRD1_k127_7047275_0	237368.SCABRO_01999	1.119e-93	318.0	COG1009@1|root,COG1009@2|Bacteria,2IX10@203682|Planctomycetes	203682|Planctomycetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRD1_k127_7047275_1	1382306.JNIM01000001_gene3462	1.513e-23	106.0	COG0713@1|root,COG0713@2|Bacteria,2G6TP@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRD1_k127_7047275_2	1385514.N782_16265	6.417e-08	56.0	COG0839@1|root,COG0839@2|Bacteria,1V6MW@1239|Firmicutes,4IRSU@91061|Bacilli	91061|Bacilli	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRD1_k127_7064099_1	1122611.KB904029_gene5414	6.367e-165	545.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4EFY3@85012|Streptosporangiales	201174|Actinobacteria	E	FAD dependent oxidoreductase central domain	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRD1_k127_7064099_5	479432.Sros_0797	2.201e-61	223.0	COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria,4EJIC@85012|Streptosporangiales	201174|Actinobacteria	M	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
SRD1_k127_7064099_6	1123023.JIAI01000001_gene6383	6.264e-51	189.0	COG1802@1|root,COG1802@2|Bacteria,2HS3R@201174|Actinobacteria,4E1VV@85010|Pseudonocardiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRD1_k127_7064099_4	1128421.JAGA01000003_gene3665	8.419e-115	377.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096,ko:K07496	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
SRD1_k127_7064099_2	266117.Rxyl_0773	1.215e-156	518.0	COG0531@1|root,COG0531@2|Bacteria,2IPSH@201174|Actinobacteria,4CQHF@84995|Rubrobacteria	84995|Rubrobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRD1_k127_7064099_3	42256.RradSPS_0636	2.722e-143	465.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CQA4@84995|Rubrobacteria	201174|Actinobacteria	C	COG COG1454 Alcohol dehydrogenase class IV Energy production and conversion	-	-	1.1.1.1,1.1.1.202	ko:K00086,ko:K11440	ko00260,ko00561,ko00640,ko01100,map00260,map00561,map00640,map01100	M00555	R02377,R03119,R08557,R08558	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Fe-ADH
SRD1_k127_7064099_0	1246995.AFR_16910	4.422e-169	556.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD1_k127_7065509_1	460265.Mnod_2306	1.718e-64	222.0	COG4221@1|root,COG4221@2|Bacteria,1MWXS@1224|Proteobacteria,2TQYY@28211|Alphaproteobacteria,1JR5N@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	MA20_32450	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD1_k127_7065509_0	1229520.ADIAL_0523	1.558e-94	323.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,4HDKW@91061|Bacilli	91061|Bacilli	Q	Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRD1_k127_7065509_3	1304275.C41B8_06537	1.363e-40	162.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,1SZ3S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRD1_k127_7065509_2	101510.RHA1_ro03302	3.24e-45	170.0	COG0665@1|root,COG0665@2|Bacteria,2I9WR@201174|Actinobacteria,4FY2U@85025|Nocardiaceae	201174|Actinobacteria	E	sarcosine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRD1_k127_7070737_5	383372.Rcas_4321	2.657e-40	151.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi,37569@32061|Chloroflexia	32061|Chloroflexia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRD1_k127_7070737_3	246194.CHY_2323	2.051e-54	194.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,42G61@68295|Thermoanaerobacterales	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRD1_k127_7070737_1	401526.TcarDRAFT_0987	2.001e-80	279.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4H228@909932|Negativicutes	909932|Negativicutes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRD1_k127_7070737_4	525904.Tter_0120	1.237e-44	168.0	COG1670@1|root,COG1670@2|Bacteria,2NPXX@2323|unclassified Bacteria	2|Bacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRD1_k127_7070737_6	401526.TcarDRAFT_0988	1.761e-39	154.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4H3ZQ@909932|Negativicutes	909932|Negativicutes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRD1_k127_7070737_7	525909.Afer_0390	7.996e-37	142.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4CN5G@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRD1_k127_7070737_0	479433.Caci_6405	1.042e-308	969.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 65, central catalytic	-	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944	2.4.1.64	ko:K05342	ko00500,ko01100,map00500,map01100	-	R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SRD1_k127_7070737_2	1133850.SHJG_2266	3.022e-73	256.0	COG0637@1|root,COG0637@2|Bacteria,2I2IT@201174|Actinobacteria	201174|Actinobacteria	G	Beta-phosphoglucomutase family hydrolase	-	GO:0003674,GO:0003824,GO:0008801,GO:0016853,GO:0016866,GO:0016868	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
SRD1_k127_7070737_8	1210908.HSB1_40310	0.0002207	45.0	COG0520@1|root,arCOG00065@2157|Archaea,2XYKY@28890|Euryarchaeota,23ZYZ@183963|Halobacteria	183963|Halobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRD1_k127_7087648_2	555088.DealDRAFT_0483	6.358e-62	220.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,42JV3@68298|Syntrophomonadaceae	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRD1_k127_7087648_1	383372.Rcas_3144	7.969e-99	338.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi,375D2@32061|Chloroflexia	32061|Chloroflexia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRD1_k127_7087648_0	246194.CHY_1492	6.814e-146	477.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,2491B@186801|Clostridia,42ERE@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Aminotransferase class I and II	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRD1_k127_7087648_3	309801.trd_A0869	3.351e-60	219.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi,27XIQ@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRD1_k127_7087673_5	1382356.JQMP01000001_gene933	5.121e-77	260.0	COG1175@1|root,COG1175@2|Bacteria,2G86U@200795|Chloroflexi,27YTK@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRD1_k127_7087673_3	926550.CLDAP_34340	1.429e-129	430.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRD1_k127_7087673_0	861299.J421_5606	2.273e-211	664.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRD1_k127_7087673_6	886293.Sinac_2247	6.473e-77	266.0	COG3970@1|root,COG3970@2|Bacteria,2IWUC@203682|Planctomycetes	203682|Planctomycetes	S	fumarylacetoacetate (FAA) hydrolase	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
SRD1_k127_7087673_2	272560.BPSS2021	4.457e-149	484.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,2W26D@28216|Betaproteobacteria,1KADQ@119060|Burkholderiaceae	28216|Betaproteobacteria	E	to Mus musculus sphingosine-1-phosphate lyase Sgpl1 SWALL O54955 (EMBL AF036894) (568 aa) fasta scores E()	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRD1_k127_7087673_1	58123.JOFJ01000021_gene3964	3.74e-165	533.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,4EPGJ@85012|Streptosporangiales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17,2.7.1.215,2.7.1.53	ko:K00854,ko:K00862,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	M00014	R01639,R01901,R07127,R11536	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRD1_k127_7087673_4	367299.JOEE01000001_gene1663	7.878e-91	312.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD1_k127_7090918_0	321327.CYA_2805	6.539e-139	469.0	COG1449@1|root,COG1449@2|Bacteria,1G1R3@1117|Cyanobacteria,1GZTF@1129|Synechococcus	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
SRD1_k127_7090918_1	1382306.JNIM01000001_gene281	2.249e-125	424.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	rfaG	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	iSDY_1059.SDY_4061	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRD1_k127_7090918_3	929712.KI912613_gene946	1.969e-38	156.0	COG0483@1|root,COG0483@2|Bacteria,2HNNN@201174|Actinobacteria,4CPT9@84995|Rubrobacteria	84995|Rubrobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRD1_k127_7090918_2	1240349.ANGC01000020_gene4256	3.687e-61	222.0	COG0596@1|root,COG0596@2|Bacteria,2GJDM@201174|Actinobacteria,4FUPB@85025|Nocardiaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRD1_k127_7090918_4	526226.Gbro_3178	1.19e-23	108.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria,4GCHG@85026|Gordoniaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
SRD1_k127_7091451_0	290397.Adeh_1948	0.0	1255.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,2YUNN@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRD1_k127_7091451_1	290397.Adeh_1584	9.104e-14	85.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2YX6I@29|Myxococcales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRD1_k127_7103031_3	1397278.AYMV01000020_gene538	2.306e-22	104.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4FKUX@85023|Microbacteriaceae	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRD1_k127_7103031_4	1133849.O3I_032185	3.686e-11	75.0	COG5513@1|root,COG5513@2|Bacteria,2GXM1@201174|Actinobacteria,4G4J0@85025|Nocardiaceae	201174|Actinobacteria	S	Chagasin family peptidase inhibitor I42	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	Inhibitor_I42
SRD1_k127_7103031_5	485913.Krac_1779	0.0001999	50.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
SRD1_k127_7103031_2	56780.SYN_02575	4.54e-28	125.0	COG4420@1|root,COG4420@2|Bacteria,1RIDY@1224|Proteobacteria,42WI7@68525|delta/epsilon subdivisions,2WSAF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
SRD1_k127_7103031_0	1041930.Mtc_1525	1.909e-57	224.0	COG5427@1|root,arCOG00563@2157|Archaea	2157|Archaea	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
SRD1_k127_7103031_1	316067.Geob_0316	3.332e-39	160.0	COG4346@1|root,COG4346@2|Bacteria,1QHX0@1224|Proteobacteria	1224|Proteobacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
SRD1_k127_711056_1	311424.DhcVS_979	5.478e-61	222.0	COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi,34D7Z@301297|Dehalococcoidia	301297|Dehalococcoidia	L	UvrD/REP helicase N-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRD1_k127_711056_0	644966.Tmar_0286	1.787e-124	420.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WCD6@538999|Clostridiales incertae sedis	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRD1_k127_7126696_2	452637.Oter_0092	5.085e-38	145.0	COG0745@1|root,COG0784@1|root,COG2202@1|root,COG3452@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3452@2|Bacteria,COG5002@2|Bacteria,46TZ6@74201|Verrucomicrobia,3K8NE@414999|Opitutae	414999|Opitutae	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRD1_k127_7126696_1	266117.Rxyl_2673	6.786e-58	222.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,2GJSK@201174|Actinobacteria	201174|Actinobacteria	T	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,PAS,Response_reg,SpoIIE
SRD1_k127_7126696_4	1292020.H483_0112890	1.421e-22	101.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRD1_k127_7126696_5	446466.Cfla_2617	1.275e-12	75.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRD1_k127_7126696_6	1254432.SCE1572_21780	1.236e-05	54.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2YUC3@29|Myxococcales	28221|Deltaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8,Response_reg
SRD1_k127_7126696_0	263358.VAB18032_15090	7.361e-72	257.0	COG2199@1|root,COG3706@2|Bacteria,2IABQ@201174|Actinobacteria,4D9W3@85008|Micromonosporales	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
SRD1_k127_7126696_3	1341151.ASZU01000021_gene1231	3.172e-29	130.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,4HAQM@91061|Bacilli,27BPK@186824|Thermoactinomycetaceae	91061|Bacilli	U	Type II/IV secretion system protein	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRD1_k127_7128238_3	1265502.KB905932_gene1849	5.945e-06	49.0	COG0500@1|root,COG0500@2|Bacteria,1RBAM@1224|Proteobacteria,2VQHX@28216|Betaproteobacteria,4AJY9@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRD1_k127_7128238_0	604331.AUHY01000007_gene725	1.577e-154	499.0	COG0399@1|root,COG0399@2|Bacteria,1WJBP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRD1_k127_7128238_1	1120746.CCNL01000010_gene1400	4.397e-51	187.0	COG2148@1|root,COG2148@2|Bacteria,2NPSP@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	bplG	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRD1_k127_7128238_2	269797.Mbar_A0025	2.777e-31	139.0	COG2244@1|root,arCOG02209@2157|Archaea,2XT90@28890|Euryarchaeota	28890|Euryarchaeota	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SRD1_k127_7128513_7	1128421.JAGA01000002_gene685	4.77e-29	123.0	COG3854@1|root,COG3854@2|Bacteria,2NQEN@2323|unclassified Bacteria	2|Bacteria	S	R3H domain	ycf45	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
SRD1_k127_7128513_6	883077.HMPREF9241_00295	1.859e-46	174.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4D3KI@85005|Actinomycetales	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3,Thymidylate_kin
SRD1_k127_7128513_8	83406.HDN1F_14560	5.895e-24	104.0	COG2076@1|root,COG2076@2|Bacteria,1MZ54@1224|Proteobacteria,1S8SG@1236|Gammaproteobacteria,1J6RR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Small Multidrug Resistance protein	-	-	-	ko:K03297	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
SRD1_k127_7128513_2	298655.KI912266_gene2716	5.62e-102	344.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4EU2D@85013|Frankiales	201174|Actinobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_7128513_0	266117.Rxyl_0614	6.141e-169	545.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,4CP7Q@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD1_k127_7128513_1	469383.Cwoe_0960	3.004e-117	388.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4CPSQ@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_7128513_3	309801.trd_0462	3.28e-77	269.0	COG2141@1|root,COG2141@2|Bacteria,2G87P@200795|Chloroflexi,27XPZ@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD1_k127_7128513_9	714961.BFZC1_23154	2.959e-19	96.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,3IVPZ@400634|Lysinibacillus	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRD1_k127_7128513_5	1313172.YM304_32940	2.75e-68	245.0	COG1387@1|root,COG1387@2|Bacteria,2GMFH@201174|Actinobacteria	201174|Actinobacteria	E	PHP domain	polX	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_8,PHP
SRD1_k127_7128513_4	880073.Calab_1145	1.274e-68	237.0	COG0302@1|root,COG0302@2|Bacteria,2NPAT@2323|unclassified Bacteria	2|Bacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRD1_k127_7153189_3	926550.CLDAP_27630	5.208e-46	189.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,2GBIY@200795|Chloroflexi	200795|Chloroflexi	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRD1_k127_7153189_1	1304880.JAGB01000001_gene507	3.936e-72	250.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_7153189_0	717605.Theco_1870	4.462e-125	431.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,26RZ6@186822|Paenibacillaceae	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRD1_k127_7153189_2	1234364.AMSF01000015_gene3086	2.568e-55	209.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,1RNP5@1236|Gammaproteobacteria,1X4HK@135614|Xanthomonadales	135614|Xanthomonadales	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRD1_k127_7155498_3	357808.RoseRS_0118	1.786e-36	152.0	COG0558@1|root,COG0558@2|Bacteria,2G9UJ@200795|Chloroflexi,377IH@32061|Chloroflexia	32061|Chloroflexia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRD1_k127_7155498_0	479434.Sthe_0282	1.983e-94	327.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi,27XU5@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRD1_k127_7155498_4	1382306.JNIM01000001_gene4123	7.807e-29	126.0	COG1560@1|root,COG1560@2|Bacteria,2G7BA@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241,2.3.1.265	ko:K02517,ko:K22311	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SRD1_k127_7155498_2	471852.Tcur_2101	2.769e-37	151.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,4EHU2@85012|Streptosporangiales	201174|Actinobacteria	M	Bacterial lipid A biosynthesis acyltransferase	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
SRD1_k127_7155498_1	867845.KI911784_gene1591	4.096e-77	261.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,374ZW@32061|Chloroflexia	32061|Chloroflexia	I	Myo-inositol-1-phosphate synthase, GAPDH domain protein	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRD1_k127_7174334_2	883078.HMPREF9695_01225	4.198e-40	151.0	COG3461@1|root,COG3461@2|Bacteria,1PX7K@1224|Proteobacteria,2V6ED@28211|Alphaproteobacteria,3K4GW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7174334_4	555088.DealDRAFT_0812	1.493e-13	80.0	COG3745@1|root,COG3745@2|Bacteria,1V5FZ@1239|Firmicutes,24I7V@186801|Clostridia,42KSY@68298|Syntrophomonadaceae	186801|Clostridia	U	TIGRFAM Flp pilus assembly protein CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
SRD1_k127_7174334_6	350054.Mflv_4388	6.619e-06	58.0	COG0664@1|root,COG0664@2|Bacteria,2IBMC@201174|Actinobacteria,238C7@1762|Mycobacteriaceae	201174|Actinobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRD1_k127_7174334_5	1120959.ATXF01000006_gene1721	3.957e-13	81.0	COG4963@1|root,COG4963@2|Bacteria,2GNHI@201174|Actinobacteria,4FS8H@85023|Microbacteriaceae	201174|Actinobacteria	D	NUBPL iron-transfer P-loop NTPase	flpE	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA
SRD1_k127_7174334_0	326427.Cagg_3210	1.182e-121	419.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi,374Z4@32061|Chloroflexia	32061|Chloroflexia	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRD1_k127_7174334_1	509191.AEDB02000063_gene451	4.353e-46	180.0	COG4965@1|root,COG4965@2|Bacteria,1UZ3V@1239|Firmicutes,25D46@186801|Clostridia,3WMV0@541000|Ruminococcaceae	186801|Clostridia	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRD1_k127_7174334_3	479434.Sthe_0521	3.012e-29	134.0	COG2064@1|root,COG2064@2|Bacteria,2G6CF@200795|Chloroflexi,27XSY@189775|Thermomicrobia	189775|Thermomicrobia	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRD1_k127_7175844_0	671143.DAMO_0532	8.732e-190	610.0	COG0085@1|root,COG0085@2|Bacteria,2NNM9@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRD1_k127_7190817_0	710696.Intca_2335	8.173e-98	326.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4FFKX@85021|Intrasporangiaceae	201174|Actinobacteria	C	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone	fgd	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0019725,GO:0030312,GO:0031406,GO:0036094,GO:0042592,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046983,GO:0048037,GO:0050662,GO:0050789,GO:0050794,GO:0055114,GO:0065007,GO:0065008,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363	1.1.98.2	ko:K15510	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
SRD1_k127_7190817_1	1380390.JIAT01000009_gene1898	1.26e-30	131.0	COG0340@1|root,COG0340@2|Bacteria,2HGFP@201174|Actinobacteria,4CQNA@84995|Rubrobacteria	84995|Rubrobacteria	H	biotin lipoate A B protein ligase	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
SRD1_k127_7190817_2	224325.AF_0112	1.321e-26	111.0	COG0846@1|root,arCOG04248@2157|Archaea,2XT4V@28890|Euryarchaeota,246N6@183980|Archaeoglobi	183980|Archaeoglobi	F	NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRD1_k127_7196609_0	1121428.DESHY_70030___1	2.534e-75	281.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,260F2@186807|Peptococcaceae	186801|Clostridia	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRD1_k127_7198822_0	1340434.AXVA01000012_gene3023	1.063e-135	441.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4HASW@91061|Bacilli,1ZB29@1386|Bacillus	91061|Bacilli	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRD1_k127_7198822_1	309801.trd_A0384	8.197e-110	376.0	COG0634@1|root,COG0634@2|Bacteria,2G6HX@200795|Chloroflexi,27XU9@189775|Thermomicrobia	189775|Thermomicrobia	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRD1_k127_7198822_3	1396141.BATP01000057_gene3021	3.697e-49	183.0	COG2518@1|root,COG2518@2|Bacteria,46V8Z@74201|Verrucomicrobia,2IUUY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	PCMT
SRD1_k127_7198822_2	1121428.DESHY_110052___1	2.37e-74	260.0	COG1615@1|root,COG1615@2|Bacteria,1TQHM@1239|Firmicutes,248PM@186801|Clostridia,260EY@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised protein family UPF0182	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRD1_k127_7202673_4	1036674.A28LD_1227	2.679e-13	71.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,2QFZX@267893|Idiomarinaceae	1236|Gammaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_0380	DMRL_synthase
SRD1_k127_7202673_1	543632.JOJL01000036_gene3013	5.509e-90	317.0	COG1520@1|root,COG1520@2|Bacteria,2I9FJ@201174|Actinobacteria	201174|Actinobacteria	M	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRD1_k127_7202673_3	1068980.ARVW01000001_gene6161	7.421e-14	76.0	COG3467@1|root,COG3467@2|Bacteria,2IR80@201174|Actinobacteria,4EBEQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K05558	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRD1_k127_7202673_0	1122223.KB890688_gene1598	3.157e-273	873.0	COG1026@1|root,COG1026@2|Bacteria,1WMAV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
SRD1_k127_7202673_2	35754.JNYJ01000094_gene9241	2.303e-15	85.0	COG3087@1|root,COG3087@2|Bacteria,2IS4S@201174|Actinobacteria,4DEVE@85008|Micromonosporales	201174|Actinobacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7202673_5	929703.KE386491_gene526	2.189e-07	63.0	COG4758@1|root,COG4758@2|Bacteria,4PN0Y@976|Bacteroidetes,47P58@768503|Cytophagia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7209951_0	671143.DAMO_2896	1.032e-73	274.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2NNZG@2323|unclassified Bacteria	2|Bacteria	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRD1_k127_7209951_1	485913.Krac_11897	9.381e-40	155.0	COG0707@1|root,COG0707@2|Bacteria,2G6CA@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase 28 domain	-	-	2.4.1.46	ko:K03715	ko00561,ko01100,map00561,map01100	-	R02691	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
SRD1_k127_7211587_0	1157490.EL26_15660	1.445e-111	373.0	COG0508@1|root,COG0508@2|Bacteria,1TQSH@1239|Firmicutes,4HBSU@91061|Bacilli,27892@186823|Alicyclobacillaceae	91061|Bacilli	C	e3 binding domain	bkdB	-	2.3.1.12,2.3.1.168	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	M00036,M00307	R00209,R02569,R02662,R03174,R04097,R10998	RC00004,RC02727,RC02742,RC02857,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRD1_k127_7211587_1	292459.STH2305	1.465e-18	89.0	COG0563@1|root,COG0563@2|Bacteria	2|Bacteria	F	adenylate kinase activity	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AAA_33,ADK,ADK_lid,SKI
SRD1_k127_7212788_1	1122222.AXWR01000028_gene951	1.023e-98	339.0	COG0044@1|root,COG0044@2|Bacteria,1WJQT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring	allB	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.5	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02425	RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRD1_k127_7212788_0	1128421.JAGA01000001_gene2232	7.152e-118	389.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	amaB	-	3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00905,R02423,R04666	RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iPC815.YPO3249	M20_dimer,OHCU_decarbox,Peptidase_M20,Peptidase_M28
SRD1_k127_7216245_1	251229.Chro_1744	5.649e-33	135.0	COG0253@1|root,COG0253@2|Bacteria,1GBIU@1117|Cyanobacteria,3VNGK@52604|Pleurocapsales	1117|Cyanobacteria	J	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	-	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRD1_k127_7216245_0	525904.Tter_1312	4.204e-119	390.0	COG2897@1|root,COG2897@2|Bacteria,2NP8T@2323|unclassified Bacteria	2|Bacteria	P	Rhodanese Homology Domain	sseA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRD1_k127_7218785_0	861299.J421_1964	1.01e-184	590.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	swrC	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRD1_k127_7223442_1	105425.BBPL01000001_gene6343	1.942e-96	321.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,2NF53@228398|Streptacidiphilus	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_7223442_0	309801.trd_0777	2.464e-114	383.0	COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi,27XU0@189775|Thermomicrobia	189775|Thermomicrobia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRD1_k127_7223442_3	269799.Gmet_2522	4.102e-29	122.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2WP7G@28221|Deltaproteobacteria,43V0M@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRD1_k127_7223442_2	326427.Cagg_2820	9.479e-60	215.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi,374V1@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
SRD1_k127_7226629_0	1429046.RR21198_5082	5.488e-99	332.0	COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria,4FV28@85025|Nocardiaceae	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRD1_k127_7226629_2	521096.Tpau_1451	1.603e-76	278.0	COG1120@1|root,COG1120@2|Bacteria,2IA4F@201174|Actinobacteria	201174|Actinobacteria	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRD1_k127_7226629_3	525909.Afer_0804	6.862e-61	219.0	COG2109@1|root,COG2109@2|Bacteria,2GNJQ@201174|Actinobacteria,4CN3K@84992|Acidimicrobiia	84992|Acidimicrobiia	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	cobO	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
SRD1_k127_7226629_5	1122622.ATWJ01000002_gene837	1.549e-40	158.0	COG2087@1|root,COG2087@2|Bacteria,2GM8Q@201174|Actinobacteria,4FHTM@85021|Intrasporangiaceae	201174|Actinobacteria	H	COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase	-	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
SRD1_k127_7226629_8	398525.KB900701_gene2492	8.226e-25	118.0	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,2U97D@28211|Alphaproteobacteria,3JUE6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
SRD1_k127_7226629_9	324602.Caur_1200	1.35e-08	62.0	COG1657@1|root,COG1657@2|Bacteria,2G7AD@200795|Chloroflexi,377CX@32061|Chloroflexia	32061|Chloroflexia	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7226629_7	1304883.KI912532_gene1364	7.752e-26	119.0	COG2045@1|root,COG2045@2|Bacteria,1N3KG@1224|Proteobacteria,2VR4U@28216|Betaproteobacteria,2KWE8@206389|Rhodocyclales	206389|Rhodocyclales	H	2-phosphosulpholactate phosphatase	-	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
SRD1_k127_7226629_11	1526927.Plano_2653	0.0001195	52.0	COG1917@1|root,COG1917@2|Bacteria,1VHKZ@1239|Firmicutes,4HP7P@91061|Bacilli,26G87@186818|Planococcaceae	91061|Bacilli	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding
SRD1_k127_7226629_4	1283287.KB822578_gene2476	5.855e-47	183.0	COG0406@1|root,COG0406@2|Bacteria,2GNRS@201174|Actinobacteria,4DQ6Z@85009|Propionibacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	gpm2	GO:0003674,GO:0003824,GO:0003993,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0042802,GO:0042803,GO:0044237,GO:0046983	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRD1_k127_7226629_10	1304885.AUEY01000003_gene534	6.146e-07	59.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,42TBQ@68525|delta/epsilon subdivisions,2WPWC@28221|Deltaproteobacteria,2MPSG@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
SRD1_k127_7226629_6	266117.Rxyl_0906	5.33e-29	119.0	COG1733@1|root,COG1733@2|Bacteria,2IQWP@201174|Actinobacteria,4CQQK@84995|Rubrobacteria	84995|Rubrobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRD1_k127_7226629_1	1123242.JH636434_gene4803	5.149e-88	301.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD1_k127_7226812_4	1540221.JQNI01000002_gene1076	6.061e-23	100.0	COG0074@1|root,COG0074@2|Bacteria,1WJBR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
SRD1_k127_7226812_5	1220583.GOACH_03_04780	3.614e-09	63.0	2EGD2@1|root,33A4V@2|Bacteria,2GWY9@201174|Actinobacteria,4GECV@85026|Gordoniaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
SRD1_k127_7226812_3	1155718.KB891967_gene7311	5.567e-34	136.0	COG0454@1|root,COG0456@2|Bacteria,2GQGN@201174|Actinobacteria	201174|Actinobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD1_k127_7226812_1	290317.Cpha266_1005	9.547e-57	210.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6,Hydrolase_4
SRD1_k127_7226812_0	1382306.JNIM01000001_gene1170	1.238e-160	516.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD1_k127_7226812_2	749927.AMED_3585	2.916e-50	182.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria,4E25B@85010|Pseudonocardiales	201174|Actinobacteria	S	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
SRD1_k127_7236694_3	1463881.KL591008_gene2092	0.0007876	47.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria	201174|Actinobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRD1_k127_7236694_2	272943.RSP_2202	2.448e-05	56.0	COG2050@1|root,COG2050@2|Bacteria,1RHK6@1224|Proteobacteria,2U72Z@28211|Alphaproteobacteria,1FBV4@1060|Rhodobacter	28211|Alphaproteobacteria	Q	Thioesterase superfamily	MA20_04725	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRD1_k127_7236694_1	485913.Krac_0164	3.014e-19	99.0	COG0454@1|root,COG0456@2|Bacteria,2G8DV@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD1_k127_7236694_0	1440053.JOEI01000029_gene4460	6.701e-23	106.0	COG1082@1|root,COG1082@2|Bacteria,2GJKJ@201174|Actinobacteria	201174|Actinobacteria	G	dehydratase	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRD1_k127_7239188_2	547042.BACCOPRO_03836	0.0003293	49.0	COG3507@1|root,COG3507@2|Bacteria,4PKZY@976|Bacteroidetes,2G09G@200643|Bacteroidia,4AV4I@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
SRD1_k127_7239188_0	1313172.YM304_37310	2.071e-37	146.0	COG3871@1|root,COG3871@2|Bacteria,2GWY2@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRD1_k127_7239188_1	1157490.EL26_16920	1.411e-06	61.0	COG0739@1|root,COG0739@2|Bacteria,1VJBW@1239|Firmicutes,4I0I7@91061|Bacilli	91061|Bacilli	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7239188_3	485913.Krac_4260	0.0005206	47.0	2DQ8Q@1|root,335AV@2|Bacteria,2G9D1@200795|Chloroflexi	200795|Chloroflexi	S	pyridoxamine 5'-phosphate oxidase-related, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRD1_k127_7249759_1	383372.Rcas_0481	3.771e-37	147.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	MA20_16785	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7249759_2	1223542.GM1_034_00210	8.198e-37	149.0	COG0494@1|root,COG0494@2|Bacteria,2II41@201174|Actinobacteria,4GASB@85026|Gordoniaceae	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRD1_k127_7249759_0	479432.Sros_6963	6.999e-51	189.0	COG0596@1|root,COG0596@2|Bacteria,2GKT5@201174|Actinobacteria,4EIZP@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRD1_k127_7257336_3	639030.JHVA01000001_gene3029	1.615e-32	135.0	COG0474@1|root,COG0474@2|Bacteria,3Y3ZX@57723|Acidobacteria,2JIQJ@204432|Acidobacteriia	204432|Acidobacteriia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.6,3.6.3.8	ko:K01535,ko:K01537	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.2,3.A.3.3	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRD1_k127_7257336_4	410359.Pcal_2109	4.582e-10	71.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRD1_k127_7257336_2	2074.JNYD01000001_gene6101	1.01e-36	145.0	COG3467@1|root,COG3467@2|Bacteria,2IAMC@201174|Actinobacteria,4ECIR@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyridox_ox_2
SRD1_k127_7257336_0	1299327.I546_3865	6.57e-108	362.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Dynamin_N,Patatin
SRD1_k127_7257336_1	1265310.CCBD010000029_gene1567	1.285e-91	317.0	COG1075@1|root,COG1075@2|Bacteria,2IBAW@201174|Actinobacteria,238FC@1762|Mycobacteriaceae	201174|Actinobacteria	S	Putative serine esterase (DUF676)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,DUF676,PGAP1
SRD1_k127_7260993_1	448385.sce8772	1.158e-127	412.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42R4P@68525|delta/epsilon subdivisions,2X5AT@28221|Deltaproteobacteria,2YWDD@29|Myxococcales	28221|Deltaproteobacteria	L	COG1484 DNA replication protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SRD1_k127_7260993_0	448385.sce8773	1.829e-167	537.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42T20@68525|delta/epsilon subdivisions,2WP7S@28221|Deltaproteobacteria,2YZ8W@29|Myxococcales	28221|Deltaproteobacteria	L	COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	rve
SRD1_k127_7260993_2	1009370.ALO_02226	1.559e-06	53.0	COG3378@1|root,COG4983@1|root,COG3378@2|Bacteria,COG4983@2|Bacteria,1TQP9@1239|Firmicutes,4H9HC@909932|Negativicutes	909932|Negativicutes	S	D5 N terminal like	-	-	-	-	-	-	-	-	-	-	-	-	D5_N
SRD1_k127_7278232_2	429009.Adeg_1883	1.765e-35	137.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,42FAT@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
SRD1_k127_7278232_3	1200792.AKYF01000004_gene6045	1.057e-32	134.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,26USM@186822|Paenibacillaceae	91061|Bacilli	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SRD1_k127_7278232_0	1449050.JNLE01000005_gene4039	2.424e-55	201.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,36W97@31979|Clostridiaceae	186801|Clostridia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_7278232_4	926550.CLDAP_31480	1.485e-31	136.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
SRD1_k127_7278232_1	429009.Adeg_1465	6.607e-38	151.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24JDV@186801|Clostridia,42G0T@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Phosphoglycerate mutase	pspA	-	3.1.3.3,3.1.3.73	ko:K02226,ko:K22305	ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130	M00122	R00582,R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRD1_k127_7278232_7	204669.Acid345_4648	0.0003462	53.0	COG0745@1|root,COG0745@2|Bacteria,3Y8XM@57723|Acidobacteria	57723|Acidobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
SRD1_k127_7278232_5	316067.Geob_2671	8.791e-09	68.0	2B9FT@1|root,322TS@2|Bacteria,1RKUJ@1224|Proteobacteria,42SNA@68525|delta/epsilon subdivisions,2WPES@28221|Deltaproteobacteria,43SKX@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7278232_6	1500301.JQMF01000014_gene4625	1.745e-05	55.0	COG3055@1|root,COG3055@2|Bacteria,1R27R@1224|Proteobacteria,2TZD2@28211|Alphaproteobacteria,4BB8D@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
SRD1_k127_7319072_2	1120972.AUMH01000020_gene2105	4.276e-86	292.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli,277XT@186823|Alicyclobacillaceae	91061|Bacilli	D	ABC transporter	ftsE	GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRD1_k127_7319072_1	926569.ANT_16650	7.198e-113	374.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRD1_k127_7319072_0	555079.Toce_1709	1.391e-261	826.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,42ETW@68295|Thermoanaerobacterales	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRD1_k127_7325358_9	926569.ANT_03800	4.076e-46	175.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi	200795|Chloroflexi	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRD1_k127_7325358_7	1027273.GZ77_01240	7.419e-48	181.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1XH4I@135619|Oceanospirillales	135619|Oceanospirillales	L	TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRD1_k127_7325358_0	765420.OSCT_1677	4.426e-257	803.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi,37527@32061|Chloroflexia	32061|Chloroflexia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRD1_k127_7325358_6	479434.Sthe_1932	1.525e-50	196.0	COG0313@1|root,COG0313@2|Bacteria,2G6E3@200795|Chloroflexi,27Y2H@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRD1_k127_7325358_1	292459.STH1713	7.895e-179	596.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,1TQHQ@1239|Firmicutes,25C6H@186801|Clostridia	186801|Clostridia	L	helicase involved in DNA repair and perhaps also replication	dinG	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T,RadC,ResIII
SRD1_k127_7325358_2	309801.trd_0219	5.797e-93	320.0	COG0464@1|root,COG0464@2|Bacteria,2G642@200795|Chloroflexi,27XW8@189775|Thermomicrobia	189775|Thermomicrobia	O	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7325358_11	1303518.CCALI_01653	1.697e-35	151.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	cmk	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase,Cytidylate_kin
SRD1_k127_7325358_10	883103.HMPREF9703_00778	9.47e-45	173.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,27G6H@186828|Carnobacteriaceae	91061|Bacilli	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRD1_k127_7325358_5	555088.DealDRAFT_0690	2.252e-63	233.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,42JUR@68298|Syntrophomonadaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRD1_k127_7325358_13	926561.KB900623_gene988	8.874e-33	138.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia,3WATD@53433|Halanaerobiales	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRD1_k127_7325358_15	926569.ANT_22490	7.426e-25	117.0	COG1354@1|root,COG1354@2|Bacteria,2G6WU@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRD1_k127_7325358_3	1379270.AUXF01000006_gene96	3.049e-90	316.0	COG0497@1|root,COG0497@2|Bacteria,1ZSV4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRD1_k127_7325358_8	498761.HM1_0298	3.784e-47	181.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
SRD1_k127_7325358_4	926569.ANT_15920	5.435e-65	233.0	COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal RNA methyltransferase RrmJ FtsJ	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRD1_k127_7325358_12	857293.CAAU_2501	5.14e-35	144.0	COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,24MV7@186801|Clostridia,36KSA@31979|Clostridiaceae	186801|Clostridia	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
SRD1_k127_7325358_14	696281.Desru_3077	3.547e-28	120.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,26201@186807|Peptococcaceae	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRD1_k127_7359156_0	1123511.KB905867_gene220	2.454e-157	514.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4H304@909932|Negativicutes	909932|Negativicutes	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
SRD1_k127_7359156_4	1123023.JIAI01000013_gene3892	1.833e-23	105.0	COG3195@1|root,COG3195@2|Bacteria,2GKIP@201174|Actinobacteria,4E5HU@85010|Pseudonocardiales	201174|Actinobacteria	S	OHCU decarboxylase	uraD	-	3.5.2.17,4.1.1.97	ko:K07127,ko:K16840	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601,R06604	RC01551,RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	OHCU_decarbox,Transthyretin
SRD1_k127_7359156_3	1155714.KB891994_gene4768	1.731e-26	111.0	COG2351@1|root,COG2351@2|Bacteria,2IQUN@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	uraH	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
SRD1_k127_7359156_2	1449976.KALB_4480	1.205e-110	371.0	COG3648@1|root,COG3648@2|Bacteria,2GK7W@201174|Actinobacteria,4DXWX@85010|Pseudonocardiales	201174|Actinobacteria	Q	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin	uox	-	1.7.3.3	ko:K00365	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	M00546	R02106,R07981	RC02107,RC02551	ko00000,ko00001,ko00002,ko01000	-	-	-	Uricase
SRD1_k127_7359156_1	266117.Rxyl_2836	8.121e-118	395.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4CQ7I@84995|Rubrobacteria	84995|Rubrobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
SRD1_k127_7381782_0	211114.JOEF01000024_gene83	5.562e-72	267.0	COG0642@1|root,COG2205@2|Bacteria,2GJKC@201174|Actinobacteria,4E0PS@85010|Pseudonocardiales	201174|Actinobacteria	T	Osmosensitive K+ channel His kinase sensor domain	kdpD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
SRD1_k127_7381782_1	1150864.MILUP08_44102	1.111e-70	241.0	COG0702@1|root,COG0702@2|Bacteria,2HVU1@201174|Actinobacteria,4D8HF@85008|Micromonosporales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRD1_k127_7392720_1	357808.RoseRS_3801	6.298e-36	140.0	COG1300@1|root,COG1300@2|Bacteria,2G8HV@200795|Chloroflexi,37546@32061|Chloroflexia	32061|Chloroflexia	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
SRD1_k127_7392720_0	357808.RoseRS_1836	1.037e-80	287.0	COG1721@1|root,COG1721@2|Bacteria,2G7PU@200795|Chloroflexi,375DS@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRD1_k127_7392720_2	1128421.JAGA01000002_gene1058	1.917e-15	77.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRD1_k127_7412542_0	1120950.KB892771_gene1287	1.208e-74	259.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria,4DPZ7@85009|Propionibacteriales	201174|Actinobacteria	C	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Bac_luciferase
SRD1_k127_7412542_1	1464048.JNZS01000016_gene3875	5.424e-56	203.0	COG3358@1|root,COG3358@2|Bacteria,2IHE3@201174|Actinobacteria,4DCTC@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SRD1_k127_7417412_3	316274.Haur_4531	1.931e-05	56.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G8F8@200795|Chloroflexi	200795|Chloroflexi	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SRD1_k127_7417412_0	526225.Gobs_4609	1.21e-82	295.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4EXEW@85013|Frankiales	201174|Actinobacteria	G	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway	mshA	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD1_k127_7417412_2	562970.Btus_1703	8.277e-06	56.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,1TRS8@1239|Firmicutes,4H9XH@91061|Bacilli,277YX@186823|Alicyclobacillaceae	91061|Bacilli	C	Cytochrome b(C-terminal)/b6/petD	qcrC	-	-	ko:K03888	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_C,Cytochrome_CBB3
SRD1_k127_7417412_1	1035308.AQYY01000002_gene479	9.55e-20	98.0	COG0707@1|root,COG0707@2|Bacteria,1UZ4A@1239|Firmicutes,249EE@186801|Clostridia	186801|Clostridia	M	PFAM Monogalactosyldiacylglycerol synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glyco_trans_1_4,MGDG_synth
SRD1_k127_7422379_1	1122611.KB903975_gene3209	8.936e-52	188.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4EN0V@85012|Streptosporangiales	201174|Actinobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRD1_k127_7422379_7	1122622.ATWJ01000012_gene1014	3.416e-05	54.0	2EIHP@1|root,33C91@2|Bacteria,2ICMY@201174|Actinobacteria,4FJY4@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
SRD1_k127_7422379_0	1429046.RR21198_4923	3.012e-85	302.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4G1Y6@85025|Nocardiaceae	201174|Actinobacteria	I	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,PAP2_3,WES_acyltransf
SRD1_k127_7422379_5	996637.SGM_2385	6.448e-18	90.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria	201174|Actinobacteria	K	pyridoxamine 5-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	HTH_3,HTH_31,Pyridox_ox_2
SRD1_k127_7422379_4	749927.AMED_5487	7.134e-21	99.0	COG0716@1|root,COG0716@2|Bacteria,2IQZD@201174|Actinobacteria,4E5JA@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Flavodoxin	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_1,Flavodoxin_5
SRD1_k127_7422379_2	351607.Acel_0525	6.889e-24	108.0	COG2210@1|root,COG2210@2|Bacteria,2IFXH@201174|Actinobacteria,4EWZZ@85013|Frankiales	201174|Actinobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRD1_k127_7422379_3	351607.Acel_0524	1.227e-22	101.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	-	-	-	-	-	-	-	-	-	-	-	-	TusA
SRD1_k127_7422379_6	351607.Acel_0523	3.167e-05	49.0	COG0446@1|root,COG0446@2|Bacteria,2GRTN@201174|Actinobacteria,4ESWT@85013|Frankiales	201174|Actinobacteria	S	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DsrC,Pyr_redox_2
SRD1_k127_7431298_1	1122221.JHVI01000020_gene1111	1.094e-15	80.0	COG0045@1|root,COG0045@2|Bacteria,1WIT1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRD1_k127_7431298_0	357808.RoseRS_3291	1.914e-156	500.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi,3750V@32061|Chloroflexia	32061|Chloroflexia	I	PFAM carboxyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRD1_k127_7451092_0	500635.MITSMUL_05455	1.416e-29	134.0	COG0739@1|root,COG0739@2|Bacteria,1V3ZU@1239|Firmicutes,4H4HE@909932|Negativicutes	909932|Negativicutes	M	Peptidase, M23 family	envC_2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRD1_k127_75242_3	1122239.AULS01000001_gene2003	4.357e-52	196.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4FMCX@85023|Microbacteriaceae	201174|Actinobacteria	E	Beta-eliminating lyase	iscS1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRD1_k127_75242_10	309801.trd_1490	2.36e-25	107.0	COG1917@1|root,COG1917@2|Bacteria,2G9S4@200795|Chloroflexi,27ZAD@189775|Thermomicrobia	189775|Thermomicrobia	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD1_k127_75242_9	255470.cbdbA378	8.629e-35	138.0	COG1656@1|root,COG1656@2|Bacteria,2G6GZ@200795|Chloroflexi,34DKC@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C
SRD1_k127_75242_2	374847.Kcr_0479	8.477e-56	213.0	COG1691@1|root,arCOG02465@2157|Archaea	2157|Archaea	S	1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRD1_k127_75242_15	1379698.RBG1_1C00001G0843	1.366e-12	79.0	COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.1.3.5	ko:K07025,ko:K08723	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRD1_k127_75242_5	1449347.JQLN01000005_gene3954	1.093e-47	176.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,2M2MN@2063|Kitasatospora	201174|Actinobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRD1_k127_75242_6	298655.KI912266_gene1786	2.421e-42	164.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria,4ESU1@85013|Frankiales	201174|Actinobacteria	H	TIGRFAM molybdenum cofactor synthesis domain	mog	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaE
SRD1_k127_75242_7	648757.Rvan_3096	1.055e-41	168.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,2TQUC@28211|Alphaproteobacteria,3N71R@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	LamB/YcsF family	ybgL	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
SRD1_k127_75242_8	1218075.BAYA01000031_gene6005	4.915e-36	154.0	2DBRF@1|root,2ZAKB@2|Bacteria,1R3HQ@1224|Proteobacteria,2WIHV@28216|Betaproteobacteria,1KISP@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_75242_1	1089544.KB912942_gene7538	2.535e-57	221.0	COG3375@1|root,COG3375@2|Bacteria,2I8MV@201174|Actinobacteria,4DZFG@85010|Pseudonocardiales	201174|Actinobacteria	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_75242_17	331869.BAL199_03974	0.0006191	46.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,4BQD8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRD1_k127_75242_13	485914.Hmuk_2683	6.451e-19	90.0	COG1225@1|root,arCOG00310@2157|Archaea,2XXB2@28890|Euryarchaeota,23VSA@183963|Halobacteria	183963|Halobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp-1	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRD1_k127_75242_11	525904.Tter_2712	8.696e-23	109.0	COG4283@1|root,COG4283@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
SRD1_k127_75242_0	1382304.JNIL01000001_gene3302	1.015e-67	245.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli	91061|Bacilli	E	allophanate hydrolase subunit 2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
SRD1_k127_75242_4	195522.BD01_1024	2.126e-49	183.0	COG2049@1|root,arCOG05809@2157|Archaea,2XUMA@28890|Euryarchaeota,242UF@183968|Thermococci	183968|Thermococci	E	Allophanate hydrolase subunit 1	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
SRD1_k127_75242_16	1380347.JNII01000008_gene4355	2.909e-11	74.0	COG2345@1|root,COG2345@2|Bacteria,2HCEF@201174|Actinobacteria,4ESVJ@85013|Frankiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRD1_k127_75242_12	477641.MODMU_4267	5.212e-20	105.0	COG2199@1|root,COG3706@2|Bacteria,2I6MR@201174|Actinobacteria	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRD1_k127_75242_14	365528.KB891236_gene30	4.485e-13	81.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRD1_k127_7532064_0	645991.Sgly_0135	2.441e-62	223.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD1_k127_7532064_1	765420.OSCT_0214	5.325e-48	188.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G66G@200795|Chloroflexi,3754U@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS
SRD1_k127_7552242_5	352165.HMPREF7215_0020	3.735e-16	81.0	COG0595@1|root,COG0595@2|Bacteria,3TABU@508458|Synergistetes	508458|Synergistetes	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
SRD1_k127_7552242_3	309801.trd_0206	6.538e-59	211.0	COG1573@1|root,COG1573@2|Bacteria,2G6BR@200795|Chloroflexi,27XM8@189775|Thermomicrobia	189775|Thermomicrobia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRD1_k127_7552242_2	767817.Desgi_1868	1.241e-81	295.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,2607M@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRD1_k127_7552242_1	436114.SYO3AOP1_0687	7.735e-104	347.0	COG0136@1|root,COG0136@2|Bacteria,2G3QW@200783|Aquificae	200783|Aquificae	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRD1_k127_7552242_4	429009.Adeg_0347	2.362e-55	216.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,42FCF@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRD1_k127_7552242_0	1131462.DCF50_p2076	6.448e-157	504.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,260DE@186807|Peptococcaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRD1_k127_75980_1	525909.Afer_1523	1.893e-74	254.0	COG1290@1|root,COG1290@2|Bacteria,2GK58@201174|Actinobacteria,4CNNI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_75980_0	235985.BBPN01000009_gene3759	6.999e-91	314.0	COG1290@1|root,COG1290@2|Bacteria,2GK58@201174|Actinobacteria,2NI2H@228398|Streptacidiphilus	201174|Actinobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_N_2
SRD1_k127_75980_2	1283283.ATXA01000001_gene460	1e-28	122.0	2A18G@1|root,30PEU@2|Bacteria,2IGED@201174|Actinobacteria,4ESR9@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7636112_0	1320556.AVBP01000013_gene1642	2.539e-115	374.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	y2-aiiA	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRD1_k127_7636112_1	861299.J421_2028	6.805e-69	244.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_2028|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7655352_0	1173027.Mic7113_0231	2.24e-52	195.0	2DBB1@1|root,2Z854@2|Bacteria,1G05N@1117|Cyanobacteria,1H7Z3@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
SRD1_k127_7655352_1	102232.GLO73106DRAFT_00019290	5.149e-15	87.0	COG1597@1|root,COG1597@2|Bacteria,1G0MV@1117|Cyanobacteria	1117|Cyanobacteria	I	PFAM Diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRD1_k127_7655352_2	1522072.IL54_1769	1.035e-13	81.0	COG0671@1|root,COG0671@2|Bacteria,1NA6H@1224|Proteobacteria,2UJ2H@28211|Alphaproteobacteria,2KDFA@204457|Sphingomonadales	204457|Sphingomonadales	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRD1_k127_7835215_1	1120999.JONM01000001_gene1273	7.877e-79	275.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VH55@28216|Betaproteobacteria,2KPJJ@206351|Neisseriales	206351|Neisseriales	E	amino acid ABC transporter	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRD1_k127_7835215_0	1485544.JQKP01000002_gene1654	1.39e-81	282.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VJAS@28216|Betaproteobacteria,44VDS@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD1_k127_7858326_1	345219.Bcoa_0489	8.563e-06	57.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4HB9Q@91061|Bacilli,1ZBKA@1386|Bacillus	91061|Bacilli	D	peptidase	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRD1_k127_7858326_0	195250.CM001776_gene1082	9.682e-159	510.0	COG1012@1|root,COG1012@2|Bacteria,1G2U1@1117|Cyanobacteria,1GYU6@1129|Synechococcus	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD1_k127_7899939_2	479434.Sthe_1200	2.288e-43	166.0	COG0193@1|root,COG0193@2|Bacteria,2G6SW@200795|Chloroflexi,27YD1@189775|Thermomicrobia	189775|Thermomicrobia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRD1_k127_7899939_3	1382304.JNIL01000001_gene887	8.748e-21	98.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,279W9@186823|Alicyclobacillaceae	91061|Bacilli	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRD1_k127_7899939_1	511051.CSE_15250	6.882e-102	344.0	COG1087@1|root,COG1087@2|Bacteria	2|Bacteria	M	UDP-glucose 4-epimerase activity	galE	-	5.1.3.2,5.1.3.25	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	M00361,M00362,M00632	R00291,R02984,R10279	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRD1_k127_7899939_0	318996.AXAZ01000004_gene6286	2.149e-111	373.0	COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,2TW46@28211|Alphaproteobacteria,3JQZM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Polysaccharide biosynthesis protein	rfbE	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRD1_k127_7899939_4	1403819.BATR01000181_gene6162	5.56e-15	84.0	COG0438@1|root,COG0438@2|Bacteria,46WHJ@74201|Verrucomicrobia,2IVEA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD1_k127_7917585_0	33876.JNXY01000031_gene2981	2.709e-09	63.0	2ADQJ@1|root,313FX@2|Bacteria,2H0DG@201174|Actinobacteria,4DDU9@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_7917585_1	1223545.GS4_19_00670	3.763e-06	59.0	2F13Q@1|root,33U55@2|Bacteria,2I955@201174|Actinobacteria,4GA3K@85026|Gordoniaceae	201174|Actinobacteria	M	Glycosyltransferase family 87	aftC	GO:0008150,GO:0040007	2.4.2.47	ko:K16647	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	GT87
SRD1_k127_83334_2	997346.HMPREF9374_0832	5.241e-100	334.0	COG1028@1|root,COG1028@2|Bacteria,1V14I@1239|Firmicutes,4HCT7@91061|Bacilli,27CRS@186824|Thermoactinomycetaceae	91061|Bacilli	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRD1_k127_83334_4	1236902.ANAS01000041_gene4365	1.313e-48	190.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4EH13@85012|Streptosporangiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA17	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD1_k127_83334_7	1214101.BN159_4305	2.812e-26	111.0	COG3795@1|root,COG3795@2|Bacteria,2IMCW@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRD1_k127_83334_1	58123.JOFJ01000010_gene797	6.596e-130	429.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4EMFS@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD1_k127_83334_6	452863.Achl_1113	1.811e-35	146.0	COG0596@1|root,COG0596@2|Bacteria,2H406@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRD1_k127_83334_3	1121946.AUAX01000023_gene4182	1.08e-73	266.0	COG0596@1|root,COG0596@2|Bacteria,2GJ4I@201174|Actinobacteria,4DM56@85008|Micromonosporales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRD1_k127_83334_5	391623.TERMP_00455	2.265e-36	147.0	COG1058@1|root,arCOG00215@2157|Archaea,2XUAN@28890|Euryarchaeota,242S9@183968|Thermococci	183968|Thermococci	S	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SRD1_k127_83334_8	926560.KE387027_gene926	9.332e-23	102.0	COG1254@1|root,COG1254@2|Bacteria,1WK7T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRD1_k127_83334_0	1382356.JQMP01000004_gene58	2.312e-248	789.0	COG3808@1|root,COG3808@2|Bacteria,2G5N7@200795|Chloroflexi,27XGS@189775|Thermomicrobia	189775|Thermomicrobia	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRD1_k127_83334_9	1122603.ATVI01000005_gene3218	1.534e-10	61.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RPJW@1236|Gammaproteobacteria,1X39K@135614|Xanthomonadales	135614|Xanthomonadales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD1_k127_866540_1	645991.Sgly_2003	2.362e-68	250.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,248WG@186801|Clostridia,261DY@186807|Peptococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990,ko:K16907	ko02010,map02010	M00224,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
SRD1_k127_866540_0	485916.Dtox_2632	2.844e-89	303.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
SRD1_k127_866540_2	1137269.AZWL01000026_gene152	1.139e-57	215.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria	201174|Actinobacteria	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRD1_k127_866540_3	298655.KI912266_gene5070	8.205e-44	171.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4EV73@85013|Frankiales	201174|Actinobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRD1_k127_891010_0	926550.CLDAP_16590	2.269e-150	484.0	COG2403@1|root,COG2403@2|Bacteria,2G7VS@200795|Chloroflexi	200795|Chloroflexi	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD1_k127_891010_1	207559.Dde_1513	6.548e-14	75.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2M88M@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRD1_k127_911532_5	1122611.KB903950_gene6435	2.129e-35	137.0	COG2346@1|root,COG2346@2|Bacteria,2IKPF@201174|Actinobacteria,4EJN6@85012|Streptosporangiales	201174|Actinobacteria	S	Bacterial-like globin	glbO	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRD1_k127_911532_3	1192034.CAP_4701	3.834e-36	156.0	COG4325@1|root,COG4325@2|Bacteria,1QKIM@1224|Proteobacteria,43411@68525|delta/epsilon subdivisions,2X4JG@28221|Deltaproteobacteria,2YZ4U@29|Myxococcales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
SRD1_k127_911532_2	526227.Mesil_0179	2.237e-60	216.0	COG0637@1|root,COG0637@2|Bacteria,1WJ5Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRD1_k127_911532_0	323259.Mhun_1465	1.407e-102	353.0	COG0205@1|root,arCOG03641@2157|Archaea	2157|Archaea	F	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRD1_k127_911532_4	926569.ANT_11280	4.986e-36	144.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRD1_k127_911532_1	1521187.JPIM01000139_gene2217	4.777e-61	222.0	COG1073@1|root,COG1073@2|Bacteria,2G73I@200795|Chloroflexi,375SM@32061|Chloroflexia	32061|Chloroflexia	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRD1_k127_911532_6	292459.STH1152	3.016e-14	79.0	COG1595@1|root,COG1595@2|Bacteria,1V9ZH@1239|Firmicutes,24NF2@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
## 2515 queries scanned
## Total time (seconds): 18.30618906021118
## Rate: 137.39 q/s