## Wed Feb 18 17:36:48 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/SRD2_bin.18.fa -m mmseqs --output SRD2_bin.18 --output_dir /data/result/bins/wyx/eggqs50+/SRD2_bin.18 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRD2_k127_1115443_2	1123267.JONN01000001_gene1626	8.108e-11	62.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2TS7S@28211|Alphaproteobacteria,2JZWE@204457|Sphingomonadales	204457|Sphingomonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRD2_k127_1115443_0	1123267.JONN01000001_gene1627	0.0	2546.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2TRHV@28211|Alphaproteobacteria,2K1CM@204457|Sphingomonadales	204457|Sphingomonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRD2_k127_1115443_1	1123267.JONN01000001_gene466	8.054e-148	470.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2TQSB@28211|Alphaproteobacteria,2K0PF@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
SRD2_k127_1115443_5	702113.PP1Y_AT6065	4.367e-06	48.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2TX4U@28211|Alphaproteobacteria,2KEIV@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRD2_k127_1516045_5	1248917.ANFX01000012_gene1776	1.221e-107	355.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2TQXA@28211|Alphaproteobacteria,2K20G@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRD2_k127_1516045_1	1449076.JOOE01000003_gene3127	2.661e-229	722.0	COG0477@1|root,COG0477@2|Bacteria,1QTYG@1224|Proteobacteria,2U3R4@28211|Alphaproteobacteria,2K1BE@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Sugar (and other) transporter	-	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1
SRD2_k127_1516045_9	1037409.BJ6T_55070	5.082e-10	72.0	2BT1Y@1|root,32N69@2|Bacteria,1R9BE@1224|Proteobacteria,2U1H7@28211|Alphaproteobacteria,3JWFK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_1516045_2	1522072.IL54_1004	7.052e-224	720.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2TRX2@28211|Alphaproteobacteria,2K00N@204457|Sphingomonadales	204457|Sphingomonadales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
SRD2_k127_1516045_3	1123267.JONN01000001_gene1701	8.441e-172	555.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2TTV2@28211|Alphaproteobacteria,2K0E5@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16
SRD2_k127_1516045_7	1123267.JONN01000001_gene1702	2.007e-75	264.0	COG1651@1|root,COG1651@2|Bacteria,1MY3H@1224|Proteobacteria,2TTXR@28211|Alphaproteobacteria,2K3ZK@204457|Sphingomonadales	204457|Sphingomonadales	O	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4
SRD2_k127_1516045_0	1112216.JH594425_gene567	1.008e-293	918.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2TTAX@28211|Alphaproteobacteria,2KDD3@204457|Sphingomonadales	204457|Sphingomonadales	E	COG1505 Serine proteases of the peptidase family S9A	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRD2_k127_1516045_6	629773.AORY01000015_gene1203	8.234e-107	351.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2TSBW@28211|Alphaproteobacteria,2K02A@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
SRD2_k127_1516045_4	1123267.JONN01000001_gene1710	3.552e-156	500.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TT2C@28211|Alphaproteobacteria,2K1HK@204457|Sphingomonadales	204457|Sphingomonadales	FP	exopolyphosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRD2_k127_1516045_8	342113.DM82_343	5.593e-52	185.0	COG3177@1|root,COG3177@2|Bacteria,1NB0K@1224|Proteobacteria,2VJAT@28216|Betaproteobacteria,1K6QV@119060|Burkholderiaceae	28216|Betaproteobacteria	S	filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRD2_k127_1574262_19	1123267.JONN01000001_gene1340	1.571e-94	323.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2TSMT@28211|Alphaproteobacteria,2K0IR@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRD2_k127_1574262_17	1123267.JONN01000001_gene1341	8.263e-107	351.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2TQK3@28211|Alphaproteobacteria,2K0KE@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRD2_k127_1574262_29	317655.Sala_1311	6.385e-55	196.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2U72Q@28211|Alphaproteobacteria,2K4KM@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRD2_k127_1574262_14	1123267.JONN01000001_gene1343	1.071e-135	435.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2TR06@28211|Alphaproteobacteria,2K0TX@204457|Sphingomonadales	204457|Sphingomonadales	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRD2_k127_1574262_18	627192.SLG_23250	9.546e-104	340.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2TUWE@28211|Alphaproteobacteria,2K0HQ@204457|Sphingomonadales	204457|Sphingomonadales	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRD2_k127_1574262_28	1123267.JONN01000001_gene1345	1.114e-56	205.0	COG0739@1|root,COG0739@2|Bacteria,1RK7E@1224|Proteobacteria,2UB7B@28211|Alphaproteobacteria,2K58B@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRD2_k127_1574262_27	1545915.JROG01000009_gene2703	1.783e-61	220.0	COG3751@1|root,COG3751@2|Bacteria,1NG7K@1224|Proteobacteria,2U773@28211|Alphaproteobacteria,2K1IN@204457|Sphingomonadales	204457|Sphingomonadales	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	1.14.11.2	ko:K00472	ko00330,ko01100,map00330,map01100	-	R01252	RC00478	ko00000,ko00001,ko01000	-	-	-	2OG-FeII_Oxy_3
SRD2_k127_1574262_20	1123267.JONN01000001_gene1349	5.008e-90	306.0	COG0352@1|root,COG0352@2|Bacteria,1MV42@1224|Proteobacteria,2TSSA@28211|Alphaproteobacteria,2K16H@204457|Sphingomonadales	204457|Sphingomonadales	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SRD2_k127_1574262_15	314266.SKA58_09876	2.219e-135	444.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,2TU2S@28211|Alphaproteobacteria,2K14P@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis	fbaB	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
SRD2_k127_1574262_7	1123267.JONN01000001_gene1353	9.186e-200	631.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2TSKQ@28211|Alphaproteobacteria,2K0JN@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRD2_k127_1574262_9	1449076.JOOE01000001_gene1911	3.454e-181	576.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2TR6E@28211|Alphaproteobacteria,2K0GC@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRD2_k127_1574262_5	1123267.JONN01000001_gene1355	1.251e-316	981.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2TQUX@28211|Alphaproteobacteria,2K0UZ@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the transketolase family	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRD2_k127_1574262_35	1123267.JONN01000001_gene1357	7.297e-33	130.0	COG3027@1|root,COG3027@2|Bacteria,1Q3M7@1224|Proteobacteria,2VACI@28211|Alphaproteobacteria,2K78U@204457|Sphingomonadales	204457|Sphingomonadales	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
SRD2_k127_1574262_34	1123267.JONN01000001_gene1358	5.665e-44	169.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2UBY4@28211|Alphaproteobacteria,2K6W9@204457|Sphingomonadales	204457|Sphingomonadales	H	5-formyltetrahydrofolate cyclo-ligase	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SRD2_k127_1574262_4	1500894.JQNN01000001_gene2118	1.507e-320	997.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,2VJYR@28216|Betaproteobacteria,474G3@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Glycosyl hydrolases family 31	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
SRD2_k127_1574262_30	1041146.ATZB01000020_gene3744	5.836e-52	189.0	COG5649@1|root,COG5649@2|Bacteria,1RGY3@1224|Proteobacteria,2U9AG@28211|Alphaproteobacteria,4BF17@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRD2_k127_1574262_24	1449065.JMLL01000012_gene3528	1.489e-70	240.0	COG0346@1|root,COG0346@2|Bacteria,1RIAM@1224|Proteobacteria,2U9TG@28211|Alphaproteobacteria,43MEK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD2_k127_1574262_25	685778.AORL01000021_gene826	1.611e-69	239.0	COG2207@1|root,COG2207@2|Bacteria,1PGN2@1224|Proteobacteria,2V7J7@28211|Alphaproteobacteria,2K80U@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRD2_k127_1574262_10	685778.AORL01000013_gene2016	9.635e-170	544.0	COG0557@1|root,COG0557@2|Bacteria,1R4RK@1224|Proteobacteria,2TTRC@28211|Alphaproteobacteria,2K2TK@204457|Sphingomonadales	204457|Sphingomonadales	K	RNB	-	-	-	-	-	-	-	-	-	-	-	-	RNB
SRD2_k127_1574262_31	1219035.NT2_02_04530	6.054e-52	185.0	2B9KW@1|root,322Z5@2|Bacteria,1RJJB@1224|Proteobacteria,2UAVD@28211|Alphaproteobacteria,2K6EC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_1574262_33	228405.HNE_1380	1.52e-47	177.0	COG0789@1|root,COG0789@2|Bacteria,1N0AZ@1224|Proteobacteria,2UAMD@28211|Alphaproteobacteria,440AN@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	ko:K08365	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRD2_k127_1574262_11	1123267.JONN01000001_gene1278	8.012e-161	529.0	COG3667@1|root,COG3667@2|Bacteria,1R6TA@1224|Proteobacteria,2U52R@28211|Alphaproteobacteria,2K3M1@204457|Sphingomonadales	204457|Sphingomonadales	P	copper resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_1574262_39	1487921.DP68_18565	5.755e-13	71.0	2E42X@1|root,32YZB@2|Bacteria,1W00A@1239|Firmicutes,255US@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_1574262_38	317655.Sala_1323	3.826e-19	90.0	28WVU@1|root,2ZIV5@2|Bacteria,1NGX2@1224|Proteobacteria,2UJJ9@28211|Alphaproteobacteria,2K6RU@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2842)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2842
SRD2_k127_1574262_23	1123267.JONN01000001_gene1360	9.107e-71	253.0	COG3773@1|root,COG3773@2|Bacteria,1RE11@1224|Proteobacteria,2U89A@28211|Alphaproteobacteria,2K11T@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell Wall Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
SRD2_k127_1574262_41	585423.KR49_00940	4.329e-07	61.0	COG2214@1|root,COG2214@2|Bacteria,1GHFB@1117|Cyanobacteria,1GYH1@1129|Synechococcus	1117|Cyanobacteria	O	COG2214 DnaJ-class molecular chaperone	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
SRD2_k127_1574262_13	1123267.JONN01000001_gene1361	8.943e-152	492.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2TVPN@28211|Alphaproteobacteria,2K11M@204457|Sphingomonadales	204457|Sphingomonadales	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRD2_k127_1574262_22	123899.JPQP01000004_gene414	1.624e-74	258.0	COG3616@1|root,COG3616@2|Bacteria,1N2SF@1224|Proteobacteria,2VJ58@28216|Betaproteobacteria,3T6C0@506|Alcaligenaceae	28216|Betaproteobacteria	E	amino acid aldolase or racemase	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRD2_k127_1574262_37	123899.JPQP01000004_gene414	1.973e-30	125.0	COG3616@1|root,COG3616@2|Bacteria,1N2SF@1224|Proteobacteria,2VJ58@28216|Betaproteobacteria,3T6C0@506|Alcaligenaceae	28216|Betaproteobacteria	E	amino acid aldolase or racemase	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRD2_k127_1574262_8	383381.EH30_05855	7.269e-190	599.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2TQPA@28211|Alphaproteobacteria,2K11C@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRD2_k127_1574262_3	1123267.JONN01000001_gene1069	5e-324	1002.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2TR86@28211|Alphaproteobacteria,2K0MC@204457|Sphingomonadales	204457|Sphingomonadales	L	ATP-dependent DNA helicase RecG	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRD2_k127_1574262_36	1123267.JONN01000001_gene1068	7.475e-31	127.0	COG2938@1|root,COG2938@2|Bacteria,1N6SJ@1224|Proteobacteria,2VCGJ@28211|Alphaproteobacteria,2K5W5@204457|Sphingomonadales	204457|Sphingomonadales	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
SRD2_k127_1574262_0	1123267.JONN01000001_gene1067	0.0	1761.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,2K07V@204457|Sphingomonadales	204457|Sphingomonadales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRD2_k127_1574262_21	1123267.JONN01000001_gene1065	2.471e-81	278.0	COG5001@1|root,COG5001@2|Bacteria,1QWUF@1224|Proteobacteria,2TX5E@28211|Alphaproteobacteria,2KEGM@204457|Sphingomonadales	204457|Sphingomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRD2_k127_1574262_16	1123267.JONN01000001_gene1064	3.755e-107	355.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2TSKN@28211|Alphaproteobacteria,2K0E6@204457|Sphingomonadales	204457|Sphingomonadales	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	ppnK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRD2_k127_1574262_12	395964.KE386496_gene433	3.64e-155	509.0	COG0446@1|root,COG2146@1|root,COG0446@2|Bacteria,COG2146@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria,3NAVA@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	Reductase C-terminal	-	-	1.18.1.1	ko:K05297	ko00071,map00071	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim,Reductase_C,Rieske
SRD2_k127_1574262_1	1123267.JONN01000001_gene1061	0.0	1466.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2TQPT@28211|Alphaproteobacteria,2K1B6@204457|Sphingomonadales	204457|Sphingomonadales	CE	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
SRD2_k127_1574262_2	1123267.JONN01000001_gene1060	0.0	1406.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria,2K1MX@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRD2_k127_1574262_26	1449076.JOOE01000001_gene2354	1.954e-67	231.0	COG3791@1|root,COG3791@2|Bacteria,1N6S5@1224|Proteobacteria,2UG0P@28211|Alphaproteobacteria,2KD97@204457|Sphingomonadales	204457|Sphingomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRD2_k127_1574262_32	1123267.JONN01000001_gene1059	2.851e-50	189.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,2K589@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRD2_k127_1574262_6	1123267.JONN01000001_gene1058	7.731e-209	670.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2TQJZ@28211|Alphaproteobacteria,2K07I@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRD2_k127_1580481_11	1123267.JONN01000001_gene1729	2.794e-24	111.0	COG3895@1|root,COG3895@2|Bacteria,1N8G9@1224|Proteobacteria,2UQIF@28211|Alphaproteobacteria,2K4MY@204457|Sphingomonadales	204457|Sphingomonadales	S	Periplasmic Protein	-	-	-	-	-	-	-	-	-	-	-	-	MliC
SRD2_k127_1580481_14	1535287.JP74_21115	1.729e-11	66.0	2E69E@1|root,330XD@2|Bacteria,1NCQU@1224|Proteobacteria,2UJ96@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	KTSC
SRD2_k127_1580481_6	1123267.JONN01000001_gene1869	1.446e-97	329.0	COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,2TVBG@28211|Alphaproteobacteria,2K0J7@204457|Sphingomonadales	204457|Sphingomonadales	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRD2_k127_1580481_4	1123267.JONN01000001_gene1868	2.96e-146	471.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2TSUA@28211|Alphaproteobacteria,2K0EJ@204457|Sphingomonadales	204457|Sphingomonadales	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRD2_k127_1580481_9	291985.CCSI01000002_gene1706	3.065e-46	177.0	COG1917@1|root,COG1917@2|Bacteria,1RHWW@1224|Proteobacteria,2U97R@28211|Alphaproteobacteria,2KE5X@204457|Sphingomonadales	204457|Sphingomonadales	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD2_k127_1580481_1	1123267.JONN01000001_gene1864	1.329e-296	919.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2TQXN@28211|Alphaproteobacteria,2K0TU@204457|Sphingomonadales	204457|Sphingomonadales	E	aminopeptidase	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
SRD2_k127_1580481_0	1123267.JONN01000001_gene1863	0.0	1019.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,2TTR0@28211|Alphaproteobacteria,2K19E@204457|Sphingomonadales	204457|Sphingomonadales	E	peptidase S9	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRD2_k127_1580481_8	317655.Sala_1841	7.567e-50	184.0	COG0824@1|root,COG0824@2|Bacteria,1N06V@1224|Proteobacteria,2UCAQ@28211|Alphaproteobacteria,2K5A4@204457|Sphingomonadales	204457|Sphingomonadales	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
SRD2_k127_1580481_7	1123267.JONN01000001_gene1860	2.123e-86	290.0	COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2U5B6@28211|Alphaproteobacteria,2K49D@204457|Sphingomonadales	204457|Sphingomonadales	O	maleylacetoacetate isomerase	-	-	5.2.1.2,5.2.1.4	ko:K01800,ko:K01801	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R03181,R03868	RC00867	ko00000,ko00001,ko00002,ko01000	-	-	-	GST_C_2,GST_N,GST_N_3
SRD2_k127_1580481_5	1123267.JONN01000001_gene1859	1.288e-140	451.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria,2K1HY@204457|Sphingomonadales	204457|Sphingomonadales	G	Aldolase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SRD2_k127_1580481_12	1081640.AGFU01000006_gene1154	4.71e-20	95.0	2DRMR@1|root,33CBA@2|Bacteria,1NK1K@1224|Proteobacteria,2UN5G@28211|Alphaproteobacteria,2K83S@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_1580481_10	1090320.KB900605_gene1497	2.03e-25	115.0	COG1846@1|root,COG1846@2|Bacteria,1NF89@1224|Proteobacteria,2UGV3@28211|Alphaproteobacteria,2K604@204457|Sphingomonadales	204457|Sphingomonadales	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
SRD2_k127_1580481_3	1449076.JOOE01000002_gene955	5.601e-154	494.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,2K18M@204457|Sphingomonadales	204457|Sphingomonadales	C	Dehydrogenase	lldD	-	1.1.2.3	ko:K00101	ko00620,ko01100,map00620,map01100	-	R00196	RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRD2_k127_1580481_2	1112214.AHIS01000091_gene973	2.807e-203	657.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K0SK@204457|Sphingomonadales	204457|Sphingomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,dCache_3
SRD2_k127_1580481_16	1479238.JQMZ01000001_gene72	7.225e-06	49.0	COG3794@1|root,COG3794@2|Bacteria,1RHQU@1224|Proteobacteria,2UBHY@28211|Alphaproteobacteria,43ZX5@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_1654438_13	1192759.AKIB01000043_gene421	3.813e-60	219.0	2ASJY@1|root,31I0J@2|Bacteria,1N0AE@1224|Proteobacteria,2UCJQ@28211|Alphaproteobacteria,2K162@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_1654438_2	1449076.JOOE01000001_gene1987	3.412e-292	914.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,2TRU4@28211|Alphaproteobacteria,2K02W@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidase M13	-	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
SRD2_k127_1654438_3	1123269.NX02_06855	9.585e-266	840.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2K0WG@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	2.7.13.3	ko:K13587	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8,Response_reg
SRD2_k127_1654438_21	1123267.JONN01000001_gene881	1.776e-40	154.0	COG0784@1|root,COG0784@2|Bacteria,1N70P@1224|Proteobacteria,2UF5P@28211|Alphaproteobacteria,2K639@204457|Sphingomonadales	204457|Sphingomonadales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRD2_k127_1654438_12	420324.KI911956_gene3445	4.593e-66	235.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria	1224|Proteobacteria	S	COG1073 hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
SRD2_k127_1654438_5	1123267.JONN01000002_gene308	8.403e-246	762.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2TS3R@28211|Alphaproteobacteria,2JZWY@204457|Sphingomonadales	204457|Sphingomonadales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRD2_k127_1654438_9	452662.SJA_C1-22130	6.69e-101	346.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,2K19X@204457|Sphingomonadales	204457|Sphingomonadales	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
SRD2_k127_1654438_0	1123267.JONN01000001_gene1128	0.0	1322.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2TR4E@28211|Alphaproteobacteria,2K15B@204457|Sphingomonadales	204457|Sphingomonadales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRD2_k127_1654438_11	178901.AmDm5_0825	3.989e-73	254.0	COG0740@1|root,COG0740@2|Bacteria,1RBNX@1224|Proteobacteria,2U5ZH@28211|Alphaproteobacteria,2JUZ1@204441|Rhodospirillales	204441|Rhodospirillales	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRD2_k127_1654438_22	392499.Swit_0045	2.921e-35	138.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2UC5G@28211|Alphaproteobacteria,2K5WD@204457|Sphingomonadales	204457|Sphingomonadales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRD2_k127_1654438_10	1123267.JONN01000001_gene1130	2.107e-88	303.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
SRD2_k127_1654438_7	1123267.JONN01000001_gene1132	8.441e-151	483.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,2VGKD@28211|Alphaproteobacteria,2K0AY@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRD2_k127_1654438_8	1123267.JONN01000001_gene1133	9.509e-114	370.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2TSW8@28211|Alphaproteobacteria,2K13J@204457|Sphingomonadales	204457|Sphingomonadales	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SRD2_k127_1654438_19	1122612.AUBA01000011_gene779	1.409e-44	169.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2U99J@28211|Alphaproteobacteria,2K56Y@204457|Sphingomonadales	204457|Sphingomonadales	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
SRD2_k127_1654438_4	1331060.RLDS_09740	2.077e-259	814.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2TRNG@28211|Alphaproteobacteria,2K1MA@204457|Sphingomonadales	204457|Sphingomonadales	O	cytochrome C	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRD2_k127_1654438_15	392499.Swit_3991	1.25e-50	185.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2TSEW@28211|Alphaproteobacteria,2K4IY@204457|Sphingomonadales	204457|Sphingomonadales	CO	Alkyl hydroperoxide reductase	ccmG	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
SRD2_k127_1654438_18	1030157.AFMP01000042_gene1291	1.526e-45	171.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2U96P@28211|Alphaproteobacteria,2K57D@204457|Sphingomonadales	204457|Sphingomonadales	O	subunit of a heme lyase	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
SRD2_k127_1654438_20	1123267.JONN01000001_gene1139	1.331e-43	171.0	COG4235@1|root,COG4235@2|Bacteria,1RB0I@1224|Proteobacteria,2U69S@28211|Alphaproteobacteria,2K4DU@204457|Sphingomonadales	204457|Sphingomonadales	O	Cytochrome c biogenesis factor	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_14,TPR_16,TPR_19
SRD2_k127_1654438_6	1123267.JONN01000001_gene1141	5.932e-204	638.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2TQQC@28211|Alphaproteobacteria,2K0C2@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRD2_k127_1654438_1	685778.AORL01000021_gene838	6.786e-302	938.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2TRVJ@28211|Alphaproteobacteria,2JZUZ@204457|Sphingomonadales	204457|Sphingomonadales	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
SRD2_k127_1654438_16	1123267.JONN01000001_gene1143	1.548e-50	186.0	COG1873@1|root,COG1873@2|Bacteria	2|Bacteria	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
SRD2_k127_1654438_14	1123267.JONN01000001_gene1144	1.208e-56	201.0	COG1514@1|root,COG1514@2|Bacteria,1RIHA@1224|Proteobacteria,2UAUZ@28211|Alphaproteobacteria,2K46A@204457|Sphingomonadales	204457|Sphingomonadales	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
SRD2_k127_1654438_17	1123267.JONN01000001_gene1145	9.89e-48	176.0	2E4J2@1|root,32ZE4@2|Bacteria,1RHJR@1224|Proteobacteria,2V5X3@28211|Alphaproteobacteria,2K5FN@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3775)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3775
SRD2_k127_1752646_13	1248916.ANFY01000004_gene1677	2.363e-90	306.0	COG0730@1|root,COG0730@2|Bacteria,1R6MR@1224|Proteobacteria,2URRK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
SRD2_k127_1752646_1	1123267.JONN01000001_gene1030	3.415e-275	849.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TSCR@28211|Alphaproteobacteria,2K06N@204457|Sphingomonadales	204457|Sphingomonadales	E	highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRD2_k127_1752646_14	1123267.JONN01000001_gene1029	2.433e-69	247.0	2AM82@1|root,31C2W@2|Bacteria,1P3W8@1224|Proteobacteria,2UVCJ@28211|Alphaproteobacteria,2KB9A@204457|Sphingomonadales	204457|Sphingomonadales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
SRD2_k127_1752646_12	1449076.JOOE01000002_gene801	1.165e-90	316.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
SRD2_k127_1752646_3	1123267.JONN01000001_gene1027	8.326e-218	685.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TRNX@28211|Alphaproteobacteria,2K03C@204457|Sphingomonadales	204457|Sphingomonadales	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRD2_k127_1752646_0	1123269.NX02_08185	0.0	1356.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,2K0C4@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
SRD2_k127_1752646_6	1007104.SUS17_2642	1.14e-186	605.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,2TRWD@28211|Alphaproteobacteria,2JZVN@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0729 Outer membrane protein	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
SRD2_k127_1752646_17	1123267.JONN01000001_gene1025	5.429e-21	93.0	2A2WA@1|root,30RAD@2|Bacteria,1NY8N@1224|Proteobacteria,2USY9@28211|Alphaproteobacteria,2K6VV@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_1752646_8	1123267.JONN01000001_gene1654	2.361e-135	454.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1R6IK@1224|Proteobacteria,2U45Y@28211|Alphaproteobacteria,2KEUW@204457|Sphingomonadales	204457|Sphingomonadales	T	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRD2_k127_1752646_15	1522072.IL54_1032	3.126e-62	219.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,2U5BS@28211|Alphaproteobacteria,2K4S9@204457|Sphingomonadales	204457|Sphingomonadales	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRD2_k127_1752646_9	1123267.JONN01000001_gene1019	3.793e-134	436.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,2TUAH@28211|Alphaproteobacteria,2JZW2@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA topoisomerase	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
SRD2_k127_1752646_11	1123267.JONN01000001_gene1018	2.137e-96	332.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,2TV9F@28211|Alphaproteobacteria,2K1C9@204457|Sphingomonadales	204457|Sphingomonadales	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRD2_k127_1752646_16	1123267.JONN01000001_gene1014	8.439e-59	210.0	COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,2U9GG@28211|Alphaproteobacteria,2K4IV@204457|Sphingomonadales	204457|Sphingomonadales	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRD2_k127_1752646_5	546414.Deide_03560	1.91e-201	632.0	COG0183@1|root,COG0183@2|Bacteria,1WIAR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRD2_k127_1752646_10	685778.AORL01000022_gene1441	3.171e-102	339.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria,2K2F3@204457|Sphingomonadales	204457|Sphingomonadales	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRD2_k127_1752646_18	13689.BV96_03733	9.566e-21	95.0	2AM08@1|root,31BTY@2|Bacteria,1NYJI@1224|Proteobacteria,2VGXW@28211|Alphaproteobacteria,2K6BP@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_1752646_7	1123267.JONN01000001_gene1009	2.824e-171	550.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,2TT27@28211|Alphaproteobacteria,2K3H0@204457|Sphingomonadales	204457|Sphingomonadales	EGP	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRD2_k127_1752646_4	1081640.AGFU01000025_gene2552	1.22e-201	633.0	COG4553@1|root,COG4553@2|Bacteria,1MVUH@1224|Proteobacteria,2TQXW@28211|Alphaproteobacteria,2K1W9@204457|Sphingomonadales	204457|Sphingomonadales	I	de-polymerase	phaZ	-	3.1.1.75	ko:K05973	ko00650,map00650	-	R05118	-	ko00000,ko00001,ko01000	-	-	-	PHB_depo_C
SRD2_k127_1752646_2	1123269.NX02_03390	3.198e-247	775.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,2K0VT@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRD2_k127_1815017_5	161528.ED21_28918	3.065e-107	356.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2TR8Z@28211|Alphaproteobacteria,2K0WU@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRD2_k127_1815017_8	1123270.ATUR01000002_gene2651	3.098e-90	312.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2TRXI@28211|Alphaproteobacteria,2JZWR@204457|Sphingomonadales	204457|Sphingomonadales	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	-	-	-	-	-	-	-	-	-	-	-	-	IlvC,IlvN
SRD2_k127_1815017_7	279238.Saro_0292	2.985e-94	311.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2TQZM@28211|Alphaproteobacteria,2K19Z@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRD2_k127_1815017_10	1411123.JQNH01000001_gene2870	4.263e-40	152.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2UBUP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRD2_k127_1815017_0	1123267.JONN01000001_gene1008	9.917e-257	804.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2TR2M@28211|Alphaproteobacteria,2K2AP@204457|Sphingomonadales	204457|Sphingomonadales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
SRD2_k127_1815017_2	1123267.JONN01000001_gene1007	2.456e-172	549.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2TTQ2@28211|Alphaproteobacteria,2K10A@204457|Sphingomonadales	204457|Sphingomonadales	D	rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRD2_k127_1815017_11	1123267.JONN01000001_gene1007	7.119e-29	115.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2TTQ2@28211|Alphaproteobacteria,2K10A@204457|Sphingomonadales	204457|Sphingomonadales	D	rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRD2_k127_1815017_4	1123267.JONN01000001_gene1006	1.103e-116	381.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2U1FY@28211|Alphaproteobacteria,2K18A@204457|Sphingomonadales	204457|Sphingomonadales	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRD2_k127_1815017_9	1123267.JONN01000001_gene1005	2.99e-56	208.0	2923J@1|root,2ZPNK@2|Bacteria,1NHX1@1224|Proteobacteria,2UC0M@28211|Alphaproteobacteria,2K5BN@204457|Sphingomonadales	204457|Sphingomonadales	S	rod shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
SRD2_k127_1815017_1	1123267.JONN01000001_gene1004	6.64e-239	760.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2TRXN@28211|Alphaproteobacteria,2JZYI@204457|Sphingomonadales	204457|Sphingomonadales	M	Penicillin-binding Protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SRD2_k127_1815017_3	1123267.JONN01000001_gene1003	7.507e-157	503.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2TSM0@28211|Alphaproteobacteria,2K0FR@204457|Sphingomonadales	204457|Sphingomonadales	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRD2_k127_1815017_6	272943.RSP_3546	1.118e-105	346.0	COG4916@1|root,COG4916@2|Bacteria,1MXWM@1224|Proteobacteria,2U2XZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRD2_k127_182803_1	1123267.JONN01000001_gene478	0.0	1251.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,2K0JK@204457|Sphingomonadales	204457|Sphingomonadales	E	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind
SRD2_k127_182803_13	1030157.AFMP01000044_gene1872	5.074e-144	475.0	COG0646@1|root,COG0646@2|Bacteria,1NPFY@1224|Proteobacteria,2UJRS@28211|Alphaproteobacteria,2K10F@204457|Sphingomonadales	204457|Sphingomonadales	E	Methionine synthase I (cobalamin-dependent), methyltransferase domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
SRD2_k127_182803_14	1123267.JONN01000001_gene476	1.438e-143	461.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2TQZA@28211|Alphaproteobacteria,2K03Q@204457|Sphingomonadales	204457|Sphingomonadales	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRD2_k127_182803_20	1030157.AFMP01000044_gene1870	1.78e-118	388.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,2TSMV@28211|Alphaproteobacteria,2K0VB@204457|Sphingomonadales	204457|Sphingomonadales	K	ArsR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Methyltransf_11
SRD2_k127_182803_3	745310.G432_16525	8.243e-308	948.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,2K0H3@204457|Sphingomonadales	204457|Sphingomonadales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRD2_k127_182803_27	1346791.M529_18170	1.398e-50	182.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2U9AQ@28211|Alphaproteobacteria,2K539@204457|Sphingomonadales	204457|Sphingomonadales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRD2_k127_182803_12	745310.G432_09425	1.161e-146	479.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2TSDU@28211|Alphaproteobacteria,2K152@204457|Sphingomonadales	204457|Sphingomonadales	V	Na -driven multidrug efflux pump	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
SRD2_k127_182803_6	1123267.JONN01000001_gene462	6.327e-208	663.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2TSXA@28211|Alphaproteobacteria,2K1TY@204457|Sphingomonadales	204457|Sphingomonadales	OU	signal peptide peptidase	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRD2_k127_182803_28	661478.OP10G_0591	6.556e-46	174.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
SRD2_k127_182803_4	745310.G432_03945	3.891e-234	730.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TRN7@28211|Alphaproteobacteria,2K1EA@204457|Sphingomonadales	204457|Sphingomonadales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRD2_k127_182803_8	745310.G432_03950	3.442e-177	564.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria,2K18R@204457|Sphingomonadales	204457|Sphingomonadales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRD2_k127_182803_0	1123267.JONN01000001_gene1672	0.0	1523.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria,2K1J3@204457|Sphingomonadales	204457|Sphingomonadales	C	E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRD2_k127_182803_11	1123267.JONN01000001_gene1673	2.034e-162	526.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2TQKB@28211|Alphaproteobacteria,2K1F5@204457|Sphingomonadales	204457|Sphingomonadales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRD2_k127_182803_10	1081640.AGFU01000020_gene1886	3.808e-163	543.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2TSV6@28211|Alphaproteobacteria,2K17I@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRD2_k127_182803_17	1304275.C41B8_09015	6.672e-133	427.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
SRD2_k127_182803_24	1123267.JONN01000001_gene1682	3.981e-63	223.0	COG2050@1|root,COG2050@2|Bacteria,1MZPH@1224|Proteobacteria,2UDIQ@28211|Alphaproteobacteria,2K62E@204457|Sphingomonadales	204457|Sphingomonadales	Q	protein, possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRD2_k127_182803_9	1123267.JONN01000001_gene1681	2.268e-163	528.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2TRG1@28211|Alphaproteobacteria,2K2A7@204457|Sphingomonadales	204457|Sphingomonadales	S	AFG1 family ATPase	-	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
SRD2_k127_182803_7	1123267.JONN01000001_gene1677	2.423e-188	603.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,2TUHT@28211|Alphaproteobacteria,2K1MW@204457|Sphingomonadales	204457|Sphingomonadales	E	Acetylornithine deacetylase Succinyl-diaminopimelate	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRD2_k127_182803_25	1081640.AGFU01000072_gene3455	2.852e-57	203.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,2K4IB@204457|Sphingomonadales	204457|Sphingomonadales	O	Alkyl hydroperoxide reductase	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRD2_k127_182803_2	1123267.JONN01000001_gene1687	7.817e-320	1005.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2TRY7@28211|Alphaproteobacteria,2K1YP@204457|Sphingomonadales	204457|Sphingomonadales	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
SRD2_k127_182803_21	1123267.JONN01000001_gene1689	1.277e-112	366.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2TUUZ@28211|Alphaproteobacteria,2K0TM@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD2_k127_182803_15	1123267.JONN01000001_gene1690	6.8e-140	449.0	COG0784@1|root,COG1595@1|root,COG0784@2|Bacteria,COG1595@2|Bacteria,1MX3Y@1224|Proteobacteria,2TT2R@28211|Alphaproteobacteria,2K0S1@204457|Sphingomonadales	204457|Sphingomonadales	T	In Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma70_r4_2
SRD2_k127_182803_16	1123267.JONN01000001_gene1691	2.5e-135	447.0	COG3920@1|root,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria,2TSSQ@28211|Alphaproteobacteria,2K1HG@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_2
SRD2_k127_182803_18	1123267.JONN01000001_gene1692	3.314e-123	402.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2TTIX@28211|Alphaproteobacteria,2K1PD@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRD2_k127_182803_29	1123267.JONN01000001_gene1693	2.243e-29	121.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2UF4Z@28211|Alphaproteobacteria,2K60Q@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRD2_k127_182803_30	1123267.JONN01000001_gene1694	1.321e-18	89.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRD2_k127_182803_23	1123267.JONN01000001_gene1695	3.056e-82	288.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2TU64@28211|Alphaproteobacteria,2K231@204457|Sphingomonadales	204457|Sphingomonadales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRD2_k127_182803_22	745310.G432_05485	1.523e-105	350.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2TS1V@28211|Alphaproteobacteria,2K15W@204457|Sphingomonadales	204457|Sphingomonadales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRD2_k127_182803_5	685778.AORL01000010_gene2580	1.618e-215	683.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,2TS7R@28211|Alphaproteobacteria,2K0U5@204457|Sphingomonadales	204457|Sphingomonadales	E	peptidase S10 serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
SRD2_k127_182803_19	1123267.JONN01000001_gene1697	1.791e-121	398.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2TRJK@28211|Alphaproteobacteria,2JZUV@204457|Sphingomonadales	204457|Sphingomonadales	G	beta-N-acetylhexosaminidase	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRD2_k127_182803_26	1123267.JONN01000001_gene1698	2.493e-56	206.0	COG3115@1|root,COG3115@2|Bacteria,1RJNQ@1224|Proteobacteria,2UC30@28211|Alphaproteobacteria,2K2NX@204457|Sphingomonadales	204457|Sphingomonadales	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
SRD2_k127_1988029_2	1449076.JOOE01000001_gene2200	1.781e-103	346.0	COG1376@1|root,COG1376@2|Bacteria,1Q823@1224|Proteobacteria,2TV64@28211|Alphaproteobacteria,2K2JH@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRD2_k127_1988029_8	314266.SKA58_15362	2.353e-25	109.0	2D1BA@1|root,32TAA@2|Bacteria,1RJQD@1224|Proteobacteria,2U780@28211|Alphaproteobacteria,2K4RE@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_1988029_1	1030157.AFMP01000036_gene2542	3.701e-133	437.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,2K0ZS@204457|Sphingomonadales	204457|Sphingomonadales	T	nitrogen fixation sensor protein fixL	-	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,PAS
SRD2_k127_1988029_3	627192.SLG_38420	3.238e-79	273.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2TUND@28211|Alphaproteobacteria,2K16W@204457|Sphingomonadales	204457|Sphingomonadales	K	part of global network that controls expression of aerobic respiratory terminal oxidases and carbon and nitrogen metabolic enzymes	-	-	-	ko:K14987	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRD2_k127_1988029_6	292415.Tbd_0006	2.358e-32	134.0	COG3467@1|root,COG3467@2|Bacteria,1RAZD@1224|Proteobacteria,2VRB2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRD2_k127_1988029_4	1449076.JOOE01000001_gene2161	1.289e-62	226.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2TV0E@28211|Alphaproteobacteria,2K40D@204457|Sphingomonadales	204457|Sphingomonadales	K	CRP FNR family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRD2_k127_1988029_5	1408224.SAMCCGM7_c3675	3.337e-35	141.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2U5MT@28211|Alphaproteobacteria,4BDWS@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006457,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0033554,GO:0034605,GO:0034620,GO:0035966,GO:0035967,GO:0042221,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0050896,GO:0051082,GO:0051716,GO:0051788,GO:0061077,GO:0070887,GO:0071218,GO:0071310	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRD2_k127_1988029_7	443598.AUFA01000004_gene5431	3.006e-28	119.0	COG3467@1|root,COG3467@2|Bacteria,1RAZD@1224|Proteobacteria,2TXIF@28211|Alphaproteobacteria,3K6W8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRD2_k127_1988029_0	1122612.AUBA01000003_gene1661	3.312e-159	512.0	28JQB@1|root,2Z9G8@2|Bacteria,1QCH9@1224|Proteobacteria,2U822@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_1991030_2	1121022.ABENE_17115	3.538e-176	564.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,2UQ63@28211|Alphaproteobacteria,2KI73@204458|Caulobacterales	204458|Caulobacterales	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
SRD2_k127_1991030_0	1449076.JOOE01000001_gene2113	2.708e-233	743.0	COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,2TTKE@28211|Alphaproteobacteria,2JZZ7@204457|Sphingomonadales	204457|Sphingomonadales	E	Tryptophan halogenase	-	-	1.14.19.9	ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
SRD2_k127_1991030_3	391600.ABRU01000050_gene199	3.658e-148	484.0	COG5520@1|root,COG5520@2|Bacteria,1N9T9@1224|Proteobacteria,2U30K@28211|Alphaproteobacteria,2KG2G@204458|Caulobacterales	204458|Caulobacterales	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
SRD2_k127_1991030_5	685778.AORL01000001_gene175	6.021e-109	376.0	COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,2TSPF@28211|Alphaproteobacteria,2K1DV@204457|Sphingomonadales	204457|Sphingomonadales	G	Major Facilitator Superfamily	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
SRD2_k127_1991030_8	1379701.JPJC01000085_gene2053	5.684e-91	307.0	COG2273@1|root,COG2273@2|Bacteria,1NFHX@1224|Proteobacteria,2U1Y8@28211|Alphaproteobacteria,2K3AK@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
SRD2_k127_1991030_7	1123270.ATUR01000002_gene2568	6.261e-95	320.0	COG2755@1|root,COG2755@2|Bacteria,1RAIX@1224|Proteobacteria,2TZF6@28211|Alphaproteobacteria,2KE5G@204457|Sphingomonadales	204457|Sphingomonadales	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_1991030_6	1112216.JH594426_gene3883	5.245e-107	372.0	COG1629@1|root,COG4771@2|Bacteria,1MWB3@1224|Proteobacteria,2U1DE@28211|Alphaproteobacteria,2K2F9@204457|Sphingomonadales	28211|Alphaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRD2_k127_1991030_4	1346791.M529_22510	2.659e-120	401.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2TTE6@28211|Alphaproteobacteria,2K1VV@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	-	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRD2_k127_1991030_1	69279.BG36_05495	9.464e-196	623.0	COG1012@1|root,COG1012@2|Bacteria,1MW72@1224|Proteobacteria,2TUN4@28211|Alphaproteobacteria,43J21@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRD2_k127_1991030_9	204669.Acid345_3656	4.207e-33	133.0	COG3191@1|root,COG3191@2|Bacteria	2|Bacteria	EQ	aminopeptidase activity	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
SRD2_k127_2008840_5	1112216.JH594425_gene977	1.353e-124	404.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,2K03K@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRD2_k127_2008840_7	1123267.JONN01000001_gene1903	1.114e-71	260.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2U59A@28211|Alphaproteobacteria,2K0G8@204457|Sphingomonadales	204457|Sphingomonadales	U	UPF0056 membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
SRD2_k127_2008840_1	1123267.JONN01000001_gene1904	1.213e-221	702.0	COG1287@1|root,COG1287@2|Bacteria,1RCIB@1224|Proteobacteria,2U677@28211|Alphaproteobacteria,2K1YU@204457|Sphingomonadales	204457|Sphingomonadales	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2008840_8	1081640.AGFU01000055_gene157	4.051e-38	163.0	COG2246@1|root,COG2246@2|Bacteria,1N67P@1224|Proteobacteria,2UDG8@28211|Alphaproteobacteria,2KE35@204457|Sphingomonadales	204457|Sphingomonadales	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRD2_k127_2008840_10	670292.JH26_08480	7.731e-23	111.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.95	ko:K05928	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07236,R07504,R10491,R10492	RC00003,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRD2_k127_2008840_3	1123267.JONN01000001_gene1907	1.843e-157	503.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2TRRT@28211|Alphaproteobacteria,2K121@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
SRD2_k127_2008840_2	1123267.JONN01000001_gene1908	6.79e-175	562.0	COG4993@1|root,COG4993@2|Bacteria,1N7DU@1224|Proteobacteria,2U6Z1@28211|Alphaproteobacteria,2K133@204457|Sphingomonadales	204457|Sphingomonadales	G	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2008840_6	1090319.KE386571_gene2585	6.799e-113	391.0	COG1287@1|root,COG1287@2|Bacteria,1RCIB@1224|Proteobacteria,2TV2J@28211|Alphaproteobacteria,2KDNP@204457|Sphingomonadales	204457|Sphingomonadales	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2008840_9	1502850.FG91_01809	1.407e-27	117.0	COG2246@1|root,COG2246@2|Bacteria,1N1WS@1224|Proteobacteria,2UCID@28211|Alphaproteobacteria,2K5Y6@204457|Sphingomonadales	204457|Sphingomonadales	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRD2_k127_2008840_0	46429.BV95_02768	1.036e-265	825.0	COG1232@1|root,COG1232@2|Bacteria,1MX35@1224|Proteobacteria,2TU7I@28211|Alphaproteobacteria,2K14D@204457|Sphingomonadales	204457|Sphingomonadales	H	Thi4 family	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRD2_k127_2008840_4	1123267.JONN01000001_gene1910	2.261e-152	496.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria,2K0PR@204457|Sphingomonadales	204457|Sphingomonadales	M	synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRD2_k127_2008840_11	633149.Bresu_0285	2.139e-18	87.0	COG3662@1|root,COG3662@2|Bacteria,1R50Q@1224|Proteobacteria,2TSG5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRD2_k127_2024815_19	1292034.OR37_04092	8.953e-10	68.0	2CNHM@1|root,32SH4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2024815_15	1219035.NT2_07_00590	1.046e-61	222.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,2K0KA@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
SRD2_k127_2024815_11	1379270.AUXF01000001_gene1925	1.383e-85	298.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56,SHD1
SRD2_k127_2024815_17	1267534.KB906758_gene2463	1.019e-50	182.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD2_k127_2024815_7	1112212.JH584235_gene1643	2.514e-150	485.0	COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,2TS8Z@28211|Alphaproteobacteria,2K0WB@204457|Sphingomonadales	204457|Sphingomonadales	E	cystathionine beta-lyase	metC	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRD2_k127_2024815_3	1123267.JONN01000001_gene1196	1.187e-225	708.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2TQQ4@28211|Alphaproteobacteria,2K181@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRD2_k127_2024815_5	1331060.RLDS_09770	2.446e-191	605.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria,2K03V@204457|Sphingomonadales	204457|Sphingomonadales	M	ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SRD2_k127_2024815_9	1335760.ASTG01000025_gene1932	1.145e-108	357.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2TSBE@28211|Alphaproteobacteria,2K04P@204457|Sphingomonadales	204457|Sphingomonadales	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
SRD2_k127_2024815_1	1161401.ASJA01000007_gene2076	2.014e-319	1021.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2TSCN@28211|Alphaproteobacteria,43X9Q@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	DNA polymerase	dnaE	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRD2_k127_2024815_18	1123267.JONN01000001_gene1201	1.836e-49	186.0	COG5592@1|root,COG5592@2|Bacteria,1N6KG@1224|Proteobacteria,2UCBE@28211|Alphaproteobacteria,2K1MZ@204457|Sphingomonadales	204457|Sphingomonadales	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRD2_k127_2024815_8	1123267.JONN01000001_gene1202	1.078e-117	386.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2U0NP@28211|Alphaproteobacteria,2K0ZN@204457|Sphingomonadales	204457|Sphingomonadales	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
SRD2_k127_2024815_12	1443665.JACA01000012_gene1185	5.713e-72	253.0	28KF8@1|root,2ZA1G@2|Bacteria,4NK7X@976|Bacteroidetes,1I0C7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2024815_0	1123267.JONN01000002_gene322	0.0	1380.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2TQV4@28211|Alphaproteobacteria,2K28K@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRD2_k127_2024815_16	743720.Psefu_4325	2.161e-55	197.0	COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,1S4HQ@1236|Gammaproteobacteria,1YZ30@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRD2_k127_2024815_4	1007104.SUS17_1101	9.824e-217	688.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,2K061@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
SRD2_k127_2024815_6	392499.Swit_0456	8.905e-155	499.0	COG0654@1|root,COG0654@2|Bacteria,1P1NX@1224|Proteobacteria,2TRZX@28211|Alphaproteobacteria,2K20R@204457|Sphingomonadales	204457|Sphingomonadales	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRD2_k127_2024815_2	1123267.JONN01000001_gene1183	2.41e-238	740.0	COG0538@1|root,COG0538@2|Bacteria,1MUIB@1224|Proteobacteria,2TQWD@28211|Alphaproteobacteria,2K05F@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRD2_k127_2024815_10	317655.Sala_1963	3.008e-98	328.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2TRMG@28211|Alphaproteobacteria,2K019@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
SRD2_k127_2024815_14	1174684.EBMC1_02685	4.211e-64	222.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2TUF7@28211|Alphaproteobacteria,2K1B9@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_tran_2,CDP-OH_P_transf
SRD2_k127_2067183_0	1123267.JONN01000001_gene1690	2.872e-139	447.0	COG0784@1|root,COG1595@1|root,COG0784@2|Bacteria,COG1595@2|Bacteria,1MX3Y@1224|Proteobacteria,2TT2R@28211|Alphaproteobacteria,2K0S1@204457|Sphingomonadales	204457|Sphingomonadales	T	In Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma70_r4_2
SRD2_k127_2067183_1	1123267.JONN01000001_gene1691	3.71e-134	444.0	COG3920@1|root,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria,2TSSQ@28211|Alphaproteobacteria,2K1HG@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_2
SRD2_k127_2067183_2	1123267.JONN01000001_gene1692	2.802e-113	370.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2TTIX@28211|Alphaproteobacteria,2K1PD@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRD2_k127_2135818_13	745310.G432_05675	4.417e-47	170.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2UBQU@28211|Alphaproteobacteria,2K561@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRD2_k127_2135818_0	1144307.PMI04_04522	2.369e-220	698.0	COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2TS4N@28211|Alphaproteobacteria,2JZUK@204457|Sphingomonadales	204457|Sphingomonadales	H	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase)	-	-	6.6.1.2	ko:K09883	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobT,CobT_C
SRD2_k127_2135818_1	1123267.JONN01000001_gene2013	1.089e-191	601.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2TS1Z@28211|Alphaproteobacteria,2K0S6@204457|Sphingomonadales	204457|Sphingomonadales	S	Aerobic cobaltochelatase subunit CobS	-	-	6.6.1.2	ko:K09882	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	AAA_5,CbbQ_C,CobS_N
SRD2_k127_2135818_5	670292.JH26_19065	1.677e-79	271.0	COG1733@1|root,COG1733@2|Bacteria,1R6MK@1224|Proteobacteria,2U2KM@28211|Alphaproteobacteria,1JV50@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	PFAM helix-turn-helix HxlR type	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,HxlR,SCP2
SRD2_k127_2135818_14	1502850.FG91_03311	2.799e-34	136.0	COG3795@1|root,COG3795@2|Bacteria,1N3WX@1224|Proteobacteria,2VC6N@28211|Alphaproteobacteria,2KARX@204457|Sphingomonadales	204457|Sphingomonadales	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRD2_k127_2135818_12	685778.AORL01000021_gene475	7.168e-54	195.0	COG3607@1|root,COG3607@2|Bacteria,1RH1T@1224|Proteobacteria,2U7DZ@28211|Alphaproteobacteria,2K69I@204457|Sphingomonadales	204457|Sphingomonadales	S	Lactoylglutathione lyase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRD2_k127_2135818_6	1123267.JONN01000001_gene2010	2.273e-78	267.0	COG0625@1|root,COG0625@2|Bacteria,1NE6Z@1224|Proteobacteria,2TVN6@28211|Alphaproteobacteria,2K4P4@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_N
SRD2_k127_2135818_4	864069.MicloDRAFT_00069530	1.065e-82	282.0	COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,2UC7A@28211|Alphaproteobacteria,1JY94@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1428)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1428
SRD2_k127_2135818_3	702113.PP1Y_AT28375	6.002e-86	293.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,2U6BE@28211|Alphaproteobacteria,2K4NC@204457|Sphingomonadales	204457|Sphingomonadales	S	enzyme related to lactoylglutathione lyase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRD2_k127_2135818_9	1300345.LF41_932	1.631e-74	253.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,1S25M@1236|Gammaproteobacteria,1X5ZR@135614|Xanthomonadales	135614|Xanthomonadales	S	3-demethylubiquinone-9 3-methyltransferase	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	3-dmu-9_3-mt
SRD2_k127_2135818_11	864069.MicloDRAFT_00069560	1.975e-66	233.0	COG0262@1|root,COG0262@2|Bacteria,1R5UU@1224|Proteobacteria,2U45H@28211|Alphaproteobacteria,1JYWZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRD2_k127_2135818_7	1123267.JONN01000001_gene2004	9.681e-78	267.0	COG0625@1|root,COG0625@2|Bacteria,1PENB@1224|Proteobacteria,2TRVC@28211|Alphaproteobacteria,2K49C@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
SRD2_k127_2135818_8	1123267.JONN01000001_gene2003	8.862e-76	258.0	COG2214@1|root,COG2214@2|Bacteria,1MXTG@1224|Proteobacteria,2TRZH@28211|Alphaproteobacteria,2K4VC@204457|Sphingomonadales	204457|Sphingomonadales	O	molecular chaperone	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
SRD2_k127_2135818_15	392499.Swit_2333	1.021e-29	122.0	COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,2UF6U@28211|Alphaproteobacteria,2K60E@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the BolA IbaG family	-	-	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
SRD2_k127_2135818_2	685035.ADAE01000018_gene933	1.051e-127	414.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,2K10E@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRD2_k127_2135818_10	84531.JMTZ01000001_gene2280	8.301e-73	248.0	2DMBA@1|root,32GFI@2|Bacteria,1RM38@1224|Proteobacteria,1SNFE@1236|Gammaproteobacteria,1X66M@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2141181_4	380394.Lferr_0203	6.793e-103	350.0	2BZPA@1|root,2ZA2G@2|Bacteria,1NUVQ@1224|Proteobacteria,1SK2E@1236|Gammaproteobacteria,2NDQ1@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
SRD2_k127_2141181_5	1219045.BV98_002583	1.043e-59	217.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,2K2BZ@204457|Sphingomonadales	204457|Sphingomonadales	KT	Domain of unknown function (DUF4118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,Trans_reg_C
SRD2_k127_2141181_8	420324.KI912011_gene9459	6.128e-21	96.0	COG4453@1|root,COG4453@2|Bacteria,1N7K8@1224|Proteobacteria,2UAFR@28211|Alphaproteobacteria,1JW95@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
SRD2_k127_2141181_0	1382303.JPOM01000001_gene814	1.348e-265	832.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2U29S@28211|Alphaproteobacteria,2KFGJ@204458|Caulobacterales	204458|Caulobacterales	S	X-Pro dipeptidyl-peptidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
SRD2_k127_2141181_6	1458357.BG58_30865	5.491e-52	192.0	COG3038@1|root,COG3038@2|Bacteria,1RDR3@1224|Proteobacteria,2W38S@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome b561	-	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
SRD2_k127_2141181_7	1267534.KB906756_gene153	2.248e-29	124.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF4440,SnoaL_2,SnoaL_3
SRD2_k127_2141181_3	1335760.ASTG01000029_gene2352	5.538e-106	353.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria,2K34A@204457|Sphingomonadales	204457|Sphingomonadales	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
SRD2_k127_2141181_2	864069.MicloDRAFT_00035180	1.881e-174	552.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TR4W@28211|Alphaproteobacteria,1JRZF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	cysB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD2_k127_2141181_10	1550073.JROH01000014_gene80	0.0001226	49.0	2AKT1@1|root,31BK2@2|Bacteria,1NXBB@1224|Proteobacteria,2UTRK@28211|Alphaproteobacteria,2K5KP@204457|Sphingomonadales	204457|Sphingomonadales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
SRD2_k127_2141181_1	1123267.JONN01000001_gene1597	9.561e-253	785.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TW3C@28211|Alphaproteobacteria,2K0HU@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C_2
SRD2_k127_2155545_11	1123267.JONN01000001_gene1377	1.759e-63	232.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2TS5S@28211|Alphaproteobacteria,2K0IG@204457|Sphingomonadales	204457|Sphingomonadales	M	membrane-bound lytic murein transglycosylase	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
SRD2_k127_2155545_8	1123267.JONN01000001_gene1378	2.842e-76	261.0	COG4395@1|root,COG4395@2|Bacteria,1NCIX@1224|Proteobacteria,2TTDQ@28211|Alphaproteobacteria,2K0UG@204457|Sphingomonadales	204457|Sphingomonadales	S	import inner membrane translocase, subunit Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
SRD2_k127_2155545_12	1123267.JONN01000001_gene1379	6.5e-60	211.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2UBTB@28211|Alphaproteobacteria,2K4QA@204457|Sphingomonadales	204457|Sphingomonadales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
SRD2_k127_2155545_1	1549858.MC45_01815	6.315e-222	700.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2TS44@28211|Alphaproteobacteria,2K03M@204457|Sphingomonadales	204457|Sphingomonadales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRD2_k127_2155545_3	1123267.JONN01000001_gene1381	2.659e-152	487.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2TQZX@28211|Alphaproteobacteria,2K24N@204457|Sphingomonadales	204457|Sphingomonadales	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRD2_k127_2155545_15	1144343.PMI41_04154	1.1e-25	114.0	COG3932@1|root,COG3932@2|Bacteria,1MZD5@1224|Proteobacteria,2U77X@28211|Alphaproteobacteria,43PW3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Exopolysaccharide synthesis, ExoD	-	-	-	-	-	-	-	-	-	-	-	-	ExoD
SRD2_k127_2155545_2	1030157.AFMP01000031_gene2866	1.013e-181	582.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2TT03@28211|Alphaproteobacteria,2JZZ0@204457|Sphingomonadales	204457|Sphingomonadales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRD2_k127_2155545_14	1088721.NSU_1331	2.751e-29	118.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2UC42@28211|Alphaproteobacteria,2K617@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRD2_k127_2155545_4	1123267.JONN01000001_gene1388	4.129e-125	407.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria,2K2A5@204457|Sphingomonadales	204457|Sphingomonadales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRD2_k127_2155545_5	1123267.JONN01000001_gene1389	8.282e-117	385.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2TRWR@28211|Alphaproteobacteria,2K080@204457|Sphingomonadales	204457|Sphingomonadales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRD2_k127_2155545_0	392499.Swit_4883	1.619e-231	728.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2TS87@28211|Alphaproteobacteria,2K1BA@204457|Sphingomonadales	204457|Sphingomonadales	S	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
SRD2_k127_2155545_9	1537715.JQFJ01000002_gene2336	2.081e-75	256.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2TRN1@28211|Alphaproteobacteria,2K0N6@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRD2_k127_2155545_7	1123267.JONN01000001_gene1395	1.116e-83	284.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2TRN1@28211|Alphaproteobacteria,2K0N6@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRD2_k127_2155545_6	1123267.JONN01000001_gene1397	1.284e-101	337.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2TRWY@28211|Alphaproteobacteria,2K1F9@204457|Sphingomonadales	204457|Sphingomonadales	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
SRD2_k127_2155545_10	392499.Swit_4879	1e-70	245.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,2K4E7@204457|Sphingomonadales	204457|Sphingomonadales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRD2_k127_2155545_13	1123267.JONN01000001_gene1398	1.925e-34	134.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,2K2HN@204457|Sphingomonadales	204457|Sphingomonadales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
SRD2_k127_2191120_17	1451261.AS96_00195	1.351e-86	291.0	COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria,4FNCM@85023|Microbacteriaceae	201174|Actinobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
SRD2_k127_2191120_9	1292034.OR37_04078	2.086e-123	408.0	COG2239@1|root,COG2239@2|Bacteria,1Q5DD@1224|Proteobacteria,2UPW8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N
SRD2_k127_2191120_22	1174684.EBMC1_10549	4.237e-73	252.0	COG1961@1|root,COG1961@2|Bacteria,1R5CS@1224|Proteobacteria,2U18D@28211|Alphaproteobacteria,2K9GH@204457|Sphingomonadales	204457|Sphingomonadales	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
SRD2_k127_2191120_10	1415778.JQMM01000001_gene967	7.296e-116	383.0	COG4974@1|root,COG4974@2|Bacteria,1P8X9@1224|Proteobacteria,1SK66@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRD2_k127_2191120_37	420662.Mpe_A3817	2.888e-23	105.0	2E48J@1|root,32Z4E@2|Bacteria,1N6PH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRD2_k127_2191120_14	595536.ADVE02000001_gene2979	2.87e-100	342.0	COG0582@1|root,COG0582@2|Bacteria,1P8BQ@1224|Proteobacteria,2TUZ9@28211|Alphaproteobacteria,36XSD@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRD2_k127_2191120_13	876269.ARWA01000001_gene1462	1.488e-102	343.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,2U0IR@28211|Alphaproteobacteria,3NBY1@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Cytochrome C oxidase subunit II, periplasmic domain	cyoA	-	1.10.3.10	ko:K02297	ko00190,ko01100,map00190,map01100	M00417	R11335	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.5	-	-	COX2,COX_ARM
SRD2_k127_2191120_2	189753.AXAS01000062_gene8431	4.25e-305	949.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,3JR26@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	cyoB	-	1.10.3.10	ko:K02298	ko00190,ko01100,map00190,map01100	M00417	R11335	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.5	-	-	COX1
SRD2_k127_2191120_24	1081640.AGFU01000002_gene454	5.868e-72	250.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2TSVR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	CytOchrome o ubiquinol oxidase	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
SRD2_k127_2191120_34	1144305.PMI02_05519	4.833e-37	153.0	COG3125@1|root,COG3125@2|Bacteria,1RHE5@1224|Proteobacteria,2U67R@28211|Alphaproteobacteria,2K6B4@204457|Sphingomonadales	204457|Sphingomonadales	C	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	ko:K02300	ko00190,ko01100,map00190,map01100	M00417	-	-	ko00000,ko00001,ko00002	3.D.4.5	-	-	COX4_pro
SRD2_k127_2191120_18	715226.ABI_44440	6.578e-83	294.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,2U0C9@28211|Alphaproteobacteria,2KGSI@204458|Caulobacterales	204458|Caulobacterales	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
SRD2_k127_2191120_6	231434.JQJH01000024_gene2100	1.361e-132	429.0	COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,2TQSM@28211|Alphaproteobacteria,3NC34@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Putative esterase	fghA	-	3.1.2.12	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R00527	RC00167,RC00320	ko00000,ko00001,ko01000	-	CE1	-	Esterase
SRD2_k127_2191120_30	13690.CP98_02984	5.499e-52	186.0	COG0346@1|root,COG0346@2|Bacteria,1RH8G@1224|Proteobacteria,2U9BR@28211|Alphaproteobacteria,2K5AH@204457|Sphingomonadales	204457|Sphingomonadales	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD2_k127_2191120_3	1331060.RLDS_23595	4.176e-218	688.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TT67@28211|Alphaproteobacteria,2K04T@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD2_k127_2191120_20	190650.CC_0409	1.1e-77	267.0	COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,2TUIN@28211|Alphaproteobacteria,2KGIT@204458|Caulobacterales	204458|Caulobacterales	F	glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase
SRD2_k127_2191120_25	1123267.JONN01000001_gene2462	2.077e-70	249.0	COG1028@1|root,COG1028@2|Bacteria,1MUS7@1224|Proteobacteria,2TTYG@28211|Alphaproteobacteria,2K4G4@204457|Sphingomonadales	204457|Sphingomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD2_k127_2191120_11	392499.Swit_0825	9.496e-110	370.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2TTEG@28211|Alphaproteobacteria,2K3PS@204457|Sphingomonadales	204457|Sphingomonadales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD2_k127_2191120_7	1305735.JAFT01000005_gene2424	1.525e-130	430.0	COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2TTX8@28211|Alphaproteobacteria,2PD7I@252301|Oceanicola	28211|Alphaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD2_k127_2191120_33	394221.Mmar10_2689	1.454e-41	162.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2U9A9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRD2_k127_2191120_5	105425.BBPL01000065_gene5343	1.919e-176	567.0	COG0365@1|root,COG0365@2|Bacteria,2GJVK@201174|Actinobacteria,2NFQ6@228398|Streptacidiphilus	201174|Actinobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRD2_k127_2191120_0	1123267.JONN01000001_gene1816	0.0	1167.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,2TR3Z@28211|Alphaproteobacteria,2K17Q@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the PEP-utilizing enzyme family	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRD2_k127_2191120_27	1123267.JONN01000001_gene1815	9.766e-65	231.0	COG1426@1|root,COG1426@2|Bacteria,1ND8D@1224|Proteobacteria,2UB49@28211|Alphaproteobacteria,2K57P@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SRD2_k127_2191120_23	1123267.JONN01000001_gene1814	3.899e-72	255.0	COG1729@1|root,COG1729@2|Bacteria,1R8C4@1224|Proteobacteria,2VBNQ@28211|Alphaproteobacteria,2K0FK@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
SRD2_k127_2191120_21	158500.BV97_03938	2.37e-77	271.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2TRK1@28211|Alphaproteobacteria,2K3YA@204457|Sphingomonadales	204457|Sphingomonadales	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
SRD2_k127_2191120_12	1123267.JONN01000002_gene155	1.081e-106	353.0	COG0412@1|root,COG0412@2|Bacteria,1NRB4@1224|Proteobacteria,2TU91@28211|Alphaproteobacteria,2K272@204457|Sphingomonadales	204457|Sphingomonadales	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRD2_k127_2191120_38	1304275.C41B8_05443	3.63e-19	90.0	2EC8I@1|root,33670@2|Bacteria,1NH09@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2191120_1	1123267.JONN01000001_gene1811	0.0	1068.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TSYQ@28211|Alphaproteobacteria,2K1U5@204457|Sphingomonadales	204457|Sphingomonadales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRD2_k127_2191120_15	1144305.PMI02_04748	2.51e-94	320.0	COG1566@1|root,COG1566@2|Bacteria,1R50C@1224|Proteobacteria,2TUCN@28211|Alphaproteobacteria,2K0QD@204457|Sphingomonadales	204457|Sphingomonadales	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
SRD2_k127_2191120_19	1219049.SP5_016_00550	5.715e-80	272.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2U6ZC@28211|Alphaproteobacteria,2K3WB@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRD2_k127_2191120_31	1123267.JONN01000001_gene1806	3.569e-51	187.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2UBSV@28211|Alphaproteobacteria,2K55D@204457|Sphingomonadales	204457|Sphingomonadales	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRD2_k127_2191120_16	1123267.JONN01000001_gene1812	1.684e-92	312.0	COG2367@1|root,COG2367@2|Bacteria,1NMW4@1224|Proteobacteria,2UBDH@28211|Alphaproteobacteria,2K2BR@204457|Sphingomonadales	204457|Sphingomonadales	V	beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2,Peptidase_S13
SRD2_k127_2191120_28	1123267.JONN01000001_gene1805	2.21e-59	212.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2U95Q@28211|Alphaproteobacteria,2K4F0@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
SRD2_k127_2191120_29	1123267.JONN01000001_gene1804	5.591e-53	201.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2TUSP@28211|Alphaproteobacteria,2K22Y@204457|Sphingomonadales	204457|Sphingomonadales	D	Membrane-bound metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRD2_k127_2191120_4	1123267.JONN01000001_gene1803	4.302e-203	640.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria,2K0TK@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRD2_k127_2191120_32	1081640.AGFU01000002_gene464	1.991e-46	173.0	COG1495@1|root,COG1495@2|Bacteria,1N89I@1224|Proteobacteria,2UF49@28211|Alphaproteobacteria,2K59V@204457|Sphingomonadales	204457|Sphingomonadales	O	Disulfide bond formation protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbB
SRD2_k127_2191120_26	1123267.JONN01000001_gene1801	3.424e-68	244.0	COG2941@1|root,COG2941@2|Bacteria,1RAK4@1224|Proteobacteria,2U85I@28211|Alphaproteobacteria,2K46W@204457|Sphingomonadales	204457|Sphingomonadales	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
SRD2_k127_2191120_36	1123267.JONN01000001_gene1800	4.7e-30	123.0	2BJB4@1|root,3186Q@2|Bacteria,1NG3X@1224|Proteobacteria,2UG56@28211|Alphaproteobacteria,2K6GS@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2191120_8	1449076.JOOE01000001_gene2245	1.246e-125	415.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,2U15C@28211|Alphaproteobacteria,2K2WX@204457|Sphingomonadales	204457|Sphingomonadales	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SRD2_k127_2329380_5	1090319.KE386571_gene1267	2.577e-96	325.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria,2JZUI@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRD2_k127_2329380_4	1123267.JONN01000001_gene1983	1.002e-103	350.0	COG3555@1|root,COG3555@2|Bacteria,1MXZE@1224|Proteobacteria,2UQPG@28211|Alphaproteobacteria,2KD8E@204457|Sphingomonadales	204457|Sphingomonadales	O	Aspartyl/Asparaginyl beta-hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Arg_Hydrox
SRD2_k127_2329380_3	392499.Swit_3142	1.152e-125	420.0	COG0457@1|root,COG0457@2|Bacteria,1RHFI@1224|Proteobacteria,2TXPR@28211|Alphaproteobacteria,2KEIN@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative 2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_5
SRD2_k127_2329380_1	450851.PHZ_c3007	1.685e-186	599.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,2KFVS@204458|Caulobacterales	204458|Caulobacterales	S	Sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_14,TPR_16,TPR_19,TPR_8
SRD2_k127_2329380_0	1123267.JONN01000001_gene1981	0.0	1427.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,2K00X@204457|Sphingomonadales	204457|Sphingomonadales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRD2_k127_2329380_6	1123267.JONN01000001_gene1980	5.387e-68	247.0	COG3108@1|root,COG3108@2|Bacteria,1N3XU@1224|Proteobacteria,2V6WT@28211|Alphaproteobacteria,2KAR6@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
SRD2_k127_2329380_7	1123267.JONN01000001_gene1979	2.727e-25	108.0	2E9WT@1|root,3342I@2|Bacteria,1NBEH@1224|Proteobacteria,2UFGC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn)	MA20_00895	-	-	-	-	-	-	-	-	-	-	-	PHA_gran_rgn
SRD2_k127_2329380_2	1123267.JONN01000001_gene1978	2.347e-179	571.0	COG0493@1|root,COG0493@2|Bacteria,1P58U@1224|Proteobacteria,2TUCG@28211|Alphaproteobacteria,2K06F@204457|Sphingomonadales	204457|Sphingomonadales	E	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
SRD2_k127_2329380_9	1265505.ATUG01000003_gene860	0.0008195	42.0	COG0642@1|root,COG2205@2|Bacteria,1R7QH@1224|Proteobacteria,42PSC@68525|delta/epsilon subdivisions,2WKFW@28221|Deltaproteobacteria,2MJNP@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
SRD2_k127_2329380_8	1282360.ABAC460_22640	9.178e-06	50.0	2C8CD@1|root,2Z9AD@2|Bacteria,1N17D@1224|Proteobacteria,2U86Q@28211|Alphaproteobacteria,2KHY9@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2335681_6	1123267.JONN01000002_gene136	5.904e-150	479.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2TQZU@28211|Alphaproteobacteria,2JZX4@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRD2_k127_2335681_9	1123267.JONN01000002_gene137	7.127e-73	248.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2U5JU@28211|Alphaproteobacteria,2K439@204457|Sphingomonadales	204457|Sphingomonadales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRD2_k127_2335681_10	1123267.JONN01000002_gene138	8.668e-68	239.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria,2K57C@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRD2_k127_2335681_16	452662.SJA_C1-14420	2.695e-31	124.0	COG0483@1|root,COG0483@2|Bacteria,1N7D7@1224|Proteobacteria,2UF6T@28211|Alphaproteobacteria,2K5WG@204457|Sphingomonadales	204457|Sphingomonadales	G	Domain of unknown function (DUF4170)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4170
SRD2_k127_2335681_19	685778.AORL01000021_gene1037	3.597e-14	81.0	28M97@1|root,2ZAN6@2|Bacteria,1P8DS@1224|Proteobacteria,2UXPS@28211|Alphaproteobacteria,2K5VF@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2335681_22	745310.G432_13070	8.392e-08	61.0	2APHC@1|root,31EKB@2|Bacteria,1QBWH@1224|Proteobacteria,2VEF2@28211|Alphaproteobacteria,2K7RB@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
SRD2_k127_2335681_21	1449076.JOOE01000001_gene1734	5.093e-08	59.0	2BJES@1|root,32DR8@2|Bacteria,1Q84X@1224|Proteobacteria,2VEAR@28211|Alphaproteobacteria,2K7D2@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRD2_k127_2335681_17	1123267.JONN01000002_gene144	2.857e-29	124.0	2EJM3@1|root,33DC0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2335681_2	1123267.JONN01000002_gene145	1.235e-218	686.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria,2K00W@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRD2_k127_2335681_14	1123267.JONN01000002_gene146	1.306e-34	135.0	COG2919@1|root,COG2919@2|Bacteria,1NGSW@1224|Proteobacteria,2UJYE@28211|Alphaproteobacteria,2K7B8@204457|Sphingomonadales	204457|Sphingomonadales	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
SRD2_k127_2335681_5	1123267.JONN01000002_gene147	1.861e-178	565.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRSS@28211|Alphaproteobacteria,2K0VG@204457|Sphingomonadales	204457|Sphingomonadales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRD2_k127_2335681_3	1090319.KE386571_gene984	7.43e-218	686.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria,2JZYC@204457|Sphingomonadales	204457|Sphingomonadales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,Transket_pyr,Transketolase_C
SRD2_k127_2335681_15	1112212.JH584235_gene3834	2.437e-32	135.0	COG1562@1|root,COG1562@2|Bacteria,1N5V2@1224|Proteobacteria,2UBZJ@28211|Alphaproteobacteria,2K4II@204457|Sphingomonadales	204457|Sphingomonadales	I	ergosterol biosynthetic process	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRD2_k127_2335681_1	1123267.JONN01000001_gene968	1.14e-224	704.0	COG1206@1|root,COG1206@2|Bacteria,1MWNQ@1224|Proteobacteria,2TR6M@28211|Alphaproteobacteria,2K17V@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
SRD2_k127_2335681_13	685778.AORL01000021_gene1023	1.811e-56	200.0	COG5483@1|root,COG5483@2|Bacteria,1N3XQ@1224|Proteobacteria,2UCV7@28211|Alphaproteobacteria,2K4V4@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRD2_k127_2335681_20	935840.JAEQ01000011_gene1772	1.934e-12	75.0	COG3652@1|root,COG3652@2|Bacteria,1N6QU@1224|Proteobacteria,2UF70@28211|Alphaproteobacteria,43Q6C@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4142)	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
SRD2_k127_2335681_11	1038860.AXAP01000006_gene6785	9.155e-68	235.0	COG5483@1|root,COG5483@2|Bacteria,1RDGV@1224|Proteobacteria,2U5GD@28211|Alphaproteobacteria,3JSGY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRD2_k127_2335681_12	1123267.JONN01000002_gene337	1.555e-59	214.0	COG5622@1|root,COG5622@2|Bacteria,1RIEJ@1224|Proteobacteria,2U7UE@28211|Alphaproteobacteria,2K400@204457|Sphingomonadales	204457|Sphingomonadales	N	Protein required for attachment to host cells	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach
SRD2_k127_2335681_0	1123267.JONN01000002_gene338	0.0	1416.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria,2K02J@204457|Sphingomonadales	204457|Sphingomonadales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRD2_k127_2335681_18	1122970.AUHC01000001_gene531	5.081e-29	131.0	COG0457@1|root,COG0457@2|Bacteria,1Q7UR@1224|Proteobacteria,2U8BX@28211|Alphaproteobacteria,2K0N1@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2335681_8	1123267.JONN01000001_gene1078	1.242e-91	320.0	COG0642@1|root,COG5330@1|root,COG2205@2|Bacteria,COG5330@2|Bacteria,1R692@1224|Proteobacteria,2U480@28211|Alphaproteobacteria,2K18H@204457|Sphingomonadales	204457|Sphingomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA
SRD2_k127_2335681_23	1121355.KB903379_gene745	3.452e-06	52.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,22JV9@1653|Corynebacteriaceae	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRD2_k127_2335681_4	1123267.JONN01000001_gene1083	7.49e-183	578.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2TQQB@28211|Alphaproteobacteria,2K118@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA repair photolyase	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRD2_k127_2335681_7	1123267.JONN01000001_gene1085	1.492e-99	334.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2U35U@28211|Alphaproteobacteria,2K136@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	SLT
SRD2_k127_2343257_0	1123267.JONN01000001_gene433	6.246e-307	949.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,2TRGM@28211|Alphaproteobacteria,2K25A@204457|Sphingomonadales	204457|Sphingomonadales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRD2_k127_2343257_2	1123267.JONN01000001_gene1723	5.426e-61	215.0	COG2198@1|root,COG2198@2|Bacteria,1NMJT@1224|Proteobacteria,2UQPF@28211|Alphaproteobacteria,2K588@204457|Sphingomonadales	204457|Sphingomonadales	T	Hpt domain	-	-	-	ko:K20976	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Hpt
SRD2_k127_2343257_1	1123267.JONN01000001_gene1722	4.276e-225	704.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2TT38@28211|Alphaproteobacteria,2K0SQ@204457|Sphingomonadales	204457|Sphingomonadales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRD2_k127_2589820_9	1123267.JONN01000001_gene2219	2.704e-35	140.0	COG5452@1|root,COG5452@2|Bacteria,1N12T@1224|Proteobacteria,2UCES@28211|Alphaproteobacteria,2K5B4@204457|Sphingomonadales	204457|Sphingomonadales	S	Ubiquinol-cytochrome C chaperone	-	-	-	ko:K17662	-	-	-	-	ko00000,ko03029	-	-	-	Ubiq_cyt_C_chap
SRD2_k127_2589820_8	1123267.JONN01000001_gene2218	7.174e-54	194.0	COG1399@1|root,COG1399@2|Bacteria,1N7C2@1224|Proteobacteria,2UC4J@28211|Alphaproteobacteria,2K4K6@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized ACR, COG1399	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
SRD2_k127_2589820_6	1123267.JONN01000001_gene2217	6.552e-61	214.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,2K464@204457|Sphingomonadales	204457|Sphingomonadales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRD2_k127_2589820_0	1123267.JONN01000001_gene2216	1.472e-275	861.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2TQSU@28211|Alphaproteobacteria,2K0AQ@204457|Sphingomonadales	204457|Sphingomonadales	P	Ferrous iron transport protein B	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
SRD2_k127_2589820_10	1123267.JONN01000001_gene2215	6.911e-27	111.0	COG1918@1|root,COG1918@2|Bacteria,1N7XK@1224|Proteobacteria,2UI27@28211|Alphaproteobacteria,2K6S7@204457|Sphingomonadales	204457|Sphingomonadales	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
SRD2_k127_2589820_5	1123267.JONN01000001_gene2214	3.366e-72	257.0	COG5590@1|root,COG5590@2|Bacteria,1MW25@1224|Proteobacteria,2U9ST@28211|Alphaproteobacteria,2K3VY@204457|Sphingomonadales	204457|Sphingomonadales	S	RpsU-divergently transcribed	-	-	-	ko:K18587	-	-	-	-	ko00000	-	-	-	COQ9
SRD2_k127_2589820_3	1123267.JONN01000001_gene2213	9.038e-101	337.0	COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,2U66Q@28211|Alphaproteobacteria,2K1CY@204457|Sphingomonadales	204457|Sphingomonadales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRD2_k127_2589820_7	1123267.JONN01000001_gene2136	2.687e-55	196.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,2U9IZ@28211|Alphaproteobacteria,2K4FR@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRD2_k127_2589820_1	1123267.JONN01000001_gene2135	1.574e-219	686.0	COG0108@1|root,COG0108@2|Bacteria,1MU8P@1224|Proteobacteria,2TSMA@28211|Alphaproteobacteria,2K1FG@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRD2_k127_2589820_4	627192.SLG_36910	8.232e-79	267.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2U3RS@28211|Alphaproteobacteria,2K0MU@204457|Sphingomonadales	204457|Sphingomonadales	H	Riboflavin synthase	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRD2_k127_2589820_2	1123267.JONN01000001_gene2133	2.536e-118	384.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2TR70@28211|Alphaproteobacteria,2K10R@204457|Sphingomonadales	204457|Sphingomonadales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRD2_k127_2615919_1	291985.CCSI01000003_gene72	1.408e-202	636.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2U3I9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRD2_k127_2615919_9	1114964.L485_08985	1.242e-88	300.0	COG0664@1|root,COG0664@2|Bacteria,1NUXB@1224|Proteobacteria,2URDT@28211|Alphaproteobacteria,2KCW1@204457|Sphingomonadales	204457|Sphingomonadales	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
SRD2_k127_2615919_2	670292.JH26_15925	2.172e-167	547.0	COG0840@1|root,COG0840@2|Bacteria,1N5N4@1224|Proteobacteria,2TVC1@28211|Alphaproteobacteria,1JU6Z@119045|Methylobacteriaceae	28211|Alphaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
SRD2_k127_2615919_5	864069.MicloDRAFT_00026040	1.582e-119	404.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,2TSA3@28211|Alphaproteobacteria,1JUYQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRD2_k127_2615919_4	1168059.KB899087_gene3191	9.042e-136	443.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2TSGV@28211|Alphaproteobacteria,3EYZS@335928|Xanthobacteraceae	28211|Alphaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SRD2_k127_2615919_6	670292.JH26_15910	3.485e-117	385.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2TUWP@28211|Alphaproteobacteria,1JTUM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
SRD2_k127_2615919_3	1123060.JONP01000071_gene4297	1.126e-165	545.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,2TSN2@28211|Alphaproteobacteria,2JRKE@204441|Rhodospirillales	204441|Rhodospirillales	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SRD2_k127_2615919_15	670292.JH26_15895	8.455e-51	182.0	COG2197@1|root,COG2197@2|Bacteria,1N7EG@1224|Proteobacteria,2UASY@28211|Alphaproteobacteria,1JVW3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRD2_k127_2615919_10	1335760.ASTG01000003_gene1534	4.97e-79	274.0	COG1776@1|root,COG1776@2|Bacteria,1R430@1224|Proteobacteria,2U4PV@28211|Alphaproteobacteria,2K8YT@204457|Sphingomonadales	204457|Sphingomonadales	NT	chemotaxis protein	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC,CheX
SRD2_k127_2615919_0	1096930.L284_22805	4.154e-221	705.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2K01C@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,ParD_antitoxin,Response_reg
SRD2_k127_2615919_11	1385521.N803_03090	7.794e-69	241.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,4FF4T@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	pcl	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRD2_k127_2615919_8	161528.ED21_23488	5.664e-100	360.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TS9V@28211|Alphaproteobacteria,2K1VI@204457|Sphingomonadales	204457|Sphingomonadales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRD2_k127_2615919_17	1218075.BAYA01000053_gene6880	4.118e-32	134.0	COG4420@1|root,COG4420@2|Bacteria,1P3R0@1224|Proteobacteria,2W6Z4@28216|Betaproteobacteria,1KDBY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2615919_19	267608.RSp0600	1.366e-12	79.0	COG4319@1|root,COG4319@2|Bacteria,1N99A@1224|Proteobacteria,2VXDG@28216|Betaproteobacteria,1K9XQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SRD2_k127_2615919_13	1297569.MESS2_730055	2.278e-57	211.0	COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria,2U4IW@28211|Alphaproteobacteria,43J44@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
SRD2_k127_2615919_7	1297569.MESS2_730056	2.543e-100	330.0	COG5588@1|root,COG5588@2|Bacteria,1RGIE@1224|Proteobacteria,2U11D@28211|Alphaproteobacteria,43RQZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
SRD2_k127_2615919_12	269482.Bcep1808_5913	1.353e-64	229.0	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,2VRSU@28216|Betaproteobacteria,1K7IJ@119060|Burkholderiaceae	28216|Betaproteobacteria	M	lipocalin	blc	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
SRD2_k127_2615919_16	983545.Glaag_2950	1.896e-38	149.0	COG0662@1|root,COG0662@2|Bacteria,1QX05@1224|Proteobacteria,1T31V@1236|Gammaproteobacteria,46D37@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD2_k127_2615919_14	1112214.AHIS01000104_gene1473	5.122e-55	201.0	2A9MH@1|root,30YU7@2|Bacteria,1PKPW@1224|Proteobacteria,2UZBV@28211|Alphaproteobacteria,2K9XN@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4337)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4337
SRD2_k127_2615919_18	401053.AciPR4_0750	3.955e-21	103.0	2DSXC@1|root,33HTB@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
SRD2_k127_2615919_21	883080.HMPREF9697_01527	2.302e-10	63.0	2EJ7M@1|root,33CYT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2615919_20	1123072.AUDH01000012_gene3551	6.95e-11	72.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2TT3G@28211|Alphaproteobacteria,2JQH9@204441|Rhodospirillales	204441|Rhodospirillales	H	TonB-dependent receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
SRD2_k127_2642215_5	1123267.JONN01000001_gene565	5.029e-58	208.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,2U2AI@28211|Alphaproteobacteria,2K0Z4@204457|Sphingomonadales	204457|Sphingomonadales	V	beta-lactamase	-	-	3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase
SRD2_k127_2642215_8	1123270.ATUR01000006_gene17	6.581e-22	100.0	COG5416@1|root,COG5416@2|Bacteria,1NFVX@1224|Proteobacteria,2UHIC@28211|Alphaproteobacteria,2K759@204457|Sphingomonadales	204457|Sphingomonadales	S	Pfam:DUF1049	-	-	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
SRD2_k127_2642215_4	1123267.JONN01000001_gene563	1.273e-85	289.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2TTB3@28211|Alphaproteobacteria,2K06D@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRD2_k127_2642215_2	1030157.AFMP01000028_gene2223	5.213e-141	451.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2TRSH@28211|Alphaproteobacteria,2K159@204457|Sphingomonadales	204457|Sphingomonadales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRD2_k127_2642215_1	745310.G432_01905	1.195e-155	513.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2TR64@28211|Alphaproteobacteria,2K1S3@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
SRD2_k127_2642215_0	1112214.AHIS01000080_gene3602	1.024e-215	685.0	COG2271@1|root,COG2271@2|Bacteria,1QUF4@1224|Proteobacteria,2TW2A@28211|Alphaproteobacteria,2KEGA@204457|Sphingomonadales	204457|Sphingomonadales	G	Acetyl-coenzyme A transporter 1	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	Acatn,MFS_1
SRD2_k127_2642215_7	13689.BV96_01857	2.552e-39	151.0	COG0745@1|root,COG0745@2|Bacteria,1N2D5@1224|Proteobacteria,2UUU2@28211|Alphaproteobacteria,2K55K@204457|Sphingomonadales	204457|Sphingomonadales	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRD2_k127_2642215_3	392499.Swit_2705	1.675e-101	344.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2TQP2@28211|Alphaproteobacteria,2K0YS@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRD2_k127_2642215_6	1123267.JONN01000001_gene1463	7.826e-54	194.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2U70Y@28211|Alphaproteobacteria,2K3X3@204457|Sphingomonadales	204457|Sphingomonadales	L	Methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRD2_k127_2651902_26	1123267.JONN01000001_gene875	2.526e-21	96.0	29188@1|root,2ZNVC@2|Bacteria,1NM5D@1224|Proteobacteria,2UMZG@28211|Alphaproteobacteria,2K7SH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2651902_24	1379701.JPJC01000229_gene2421	1.933e-21	98.0	2A2WM@1|root,30RAQ@2|Bacteria,1NC0Y@1224|Proteobacteria,2UGYZ@28211|Alphaproteobacteria,2K6WP@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2651902_4	1123267.JONN01000001_gene955	2.434e-189	602.0	COG3724@1|root,COG3724@2|Bacteria,1MUJV@1224|Proteobacteria,2U0HD@28211|Alphaproteobacteria,2K01P@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)	astB	-	3.5.3.23	ko:K01484	ko00330,ko01100,map00330,map01100	-	R04189	RC00024	ko00000,ko00001,ko01000	-	-	-	AstB
SRD2_k127_2651902_9	1123267.JONN01000001_gene956	1.313e-156	511.0	COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,2TREF@28211|Alphaproteobacteria,2K0MB@204457|Sphingomonadales	204457|Sphingomonadales	E	arginine N-succinyltransferase	astA	-	2.3.1.109	ko:K00673	ko00330,ko01100,map00330,map01100	-	R00832	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	AstA
SRD2_k127_2651902_8	1346791.M529_21160	5.888e-160	514.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2TRTW@28211|Alphaproteobacteria,2K0AC@204457|Sphingomonadales	204457|Sphingomonadales	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRD2_k127_2651902_29	69042.WH5701_09209	8.589e-07	60.0	COG4916@1|root,COG4916@2|Bacteria	2|Bacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2,TIR_2
SRD2_k127_2651902_17	349521.HCH_00113	3.938e-70	249.0	COG5000@1|root,COG5000@2|Bacteria,1R45S@1224|Proteobacteria,1RY7Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP
SRD2_k127_2651902_13	1057002.KB905370_gene2611	3.364e-110	379.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_8
SRD2_k127_2651902_11	1057002.KB905370_gene2611	3.426e-119	404.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_8
SRD2_k127_2651902_16	1123267.JONN01000001_gene897	1.837e-72	246.0	COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,2TW25@28211|Alphaproteobacteria,2K4S3@204457|Sphingomonadales	204457|Sphingomonadales	F	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
SRD2_k127_2651902_1	1123267.JONN01000001_gene900	0.0	1041.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,2K2JW@204457|Sphingomonadales	204457|Sphingomonadales	C	COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRD2_k127_2651902_7	1123267.JONN01000001_gene902	1.798e-180	572.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2TR4R@28211|Alphaproteobacteria,2K1JI@204457|Sphingomonadales	204457|Sphingomonadales	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRD2_k127_2651902_18	1174684.EBMC1_16144	9.409e-68	241.0	COG1988@1|root,COG1988@2|Bacteria,1RA9E@1224|Proteobacteria,2U5TK@28211|Alphaproteobacteria,2K3A3@204457|Sphingomonadales	204457|Sphingomonadales	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
SRD2_k127_2651902_6	1123267.JONN01000001_gene906	1.046e-180	575.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria,2K1IB@204457|Sphingomonadales	204457|Sphingomonadales	M	synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRD2_k127_2651902_19	392499.Swit_3426	1.205e-66	237.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U182@28211|Alphaproteobacteria,2KD1K@204457|Sphingomonadales	204457|Sphingomonadales	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD2_k127_2651902_25	392499.Swit_3424	2.325e-21	100.0	COG3794@1|root,COG3794@2|Bacteria,1PPV9@1224|Proteobacteria,2UH4U@28211|Alphaproteobacteria,2K7FU@204457|Sphingomonadales	204457|Sphingomonadales	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2651902_20	1380355.JNIJ01000010_gene1556	2.299e-55	200.0	COG3652@1|root,COG3652@2|Bacteria,1RDPI@1224|Proteobacteria,2TUSW@28211|Alphaproteobacteria,3JWFC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4142)	MA20_42090	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
SRD2_k127_2651902_14	1123267.JONN01000001_gene908	1.316e-90	306.0	COG0300@1|root,COG0300@2|Bacteria,1QUNR@1224|Proteobacteria,2TW24@28211|Alphaproteobacteria,2K1AC@204457|Sphingomonadales	204457|Sphingomonadales	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD2_k127_2651902_23	1267533.KB906737_gene1984	3.279e-40	163.0	COG4270@1|root,COG4270@2|Bacteria,3Y68W@57723|Acidobacteria	57723|Acidobacteria	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRD2_k127_2651902_3	1123267.JONN01000002_gene150	4.632e-256	799.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2TR8V@28211|Alphaproteobacteria,2K0C0@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
SRD2_k127_2651902_15	1123267.JONN01000001_gene1606	2.253e-74	255.0	COG0225@1|root,COG0225@2|Bacteria,1NC84@1224|Proteobacteria,2TTDD@28211|Alphaproteobacteria,2K3XP@204457|Sphingomonadales	204457|Sphingomonadales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA_1	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRD2_k127_2651902_2	1123267.JONN01000002_gene152	1.596e-268	837.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria,2K0RG@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
SRD2_k127_2651902_22	1112214.AHIS01000047_gene2140	1.379e-51	192.0	COG4798@1|root,COG4798@2|Bacteria,1RHGZ@1224|Proteobacteria,2U7R8@28211|Alphaproteobacteria,2KDKG@204457|Sphingomonadales	204457|Sphingomonadales	S	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2651902_21	404380.Gbem_2014	1.276e-52	193.0	2ADQJ@1|root,313FX@2|Bacteria,1MYNR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2651902_12	1123267.JONN01000001_gene2393	1.111e-116	389.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,2K19X@204457|Sphingomonadales	204457|Sphingomonadales	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
SRD2_k127_2651902_0	1123267.JONN01000001_gene959	0.0	1085.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K07A@204457|Sphingomonadales	204457|Sphingomonadales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PilZ
SRD2_k127_2651902_10	1346791.M529_12325	2.758e-154	512.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria,2K2A3@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD2_k127_2651902_5	745310.G432_03695	2.909e-189	601.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,2TUM5@28211|Alphaproteobacteria,2K1MY@204457|Sphingomonadales	204457|Sphingomonadales	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRD2_k127_2672568_12	1123267.JONN01000001_gene536	1.83e-104	343.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria,2K21H@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
SRD2_k127_2672568_10	1123267.JONN01000001_gene535	3.622e-117	381.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2TU7F@28211|Alphaproteobacteria,2K0K0@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
SRD2_k127_2672568_21	1123267.JONN01000001_gene534	2.299e-19	94.0	2AI43@1|root,318I3@2|Bacteria,1NCMB@1224|Proteobacteria,2UFPI@28211|Alphaproteobacteria,2K76K@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2672568_8	1123267.JONN01000001_gene533	8.56e-136	438.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2TTUR@28211|Alphaproteobacteria,2K0YD@204457|Sphingomonadales	204457|Sphingomonadales	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
SRD2_k127_2672568_4	1123267.JONN01000001_gene532	1.395e-206	649.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2TSGT@28211|Alphaproteobacteria,2K0I4@204457|Sphingomonadales	204457|Sphingomonadales	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD2_k127_2672568_9	1123267.JONN01000001_gene530	1.867e-129	422.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2TQSY@28211|Alphaproteobacteria,2K23E@204457|Sphingomonadales	204457|Sphingomonadales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRD2_k127_2672568_13	1123267.JONN01000001_gene529	6.03e-92	323.0	COG5352@1|root,COG5352@2|Bacteria,1RHI6@1224|Proteobacteria,2TS7F@28211|Alphaproteobacteria,2K0A1@204457|Sphingomonadales	204457|Sphingomonadales	S	GcrA cell cycle regulator	-	-	-	ko:K13583	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	GcrA
SRD2_k127_2672568_20	1090319.KE386571_gene2291	1.291e-34	154.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2TU4E@28211|Alphaproteobacteria,2K07U@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRD2_k127_2672568_11	1123269.NX02_27645	2.144e-105	376.0	COG2267@1|root,COG3629@1|root,COG2267@2|Bacteria,COG3629@2|Bacteria,1QU9N@1224|Proteobacteria,2TW44@28211|Alphaproteobacteria,2K7FJ@204457|Sphingomonadales	204457|Sphingomonadales	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRD2_k127_2672568_16	935840.JAEQ01000029_gene672	1.849e-65	253.0	COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,2TW52@28211|Alphaproteobacteria,43M0X@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
SRD2_k127_2672568_14	450851.PHZ_c1673	2.049e-81	281.0	2CCCK@1|root,2Z7UH@2|Bacteria,1R3SV@1224|Proteobacteria,2UH90@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2672568_17	1123269.NX02_27640	3.447e-63	222.0	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,2U1VW@28211|Alphaproteobacteria,2K5RK@204457|Sphingomonadales	204457|Sphingomonadales	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRD2_k127_2672568_19	1007104.SUS17_3578	1.437e-56	205.0	COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,2U96D@28211|Alphaproteobacteria,2K489@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K04080	-	-	-	-	ko00000,ko03110	-	-	-	HSP20
SRD2_k127_2672568_0	1123267.JONN01000001_gene527	0.0	1083.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2TQZV@28211|Alphaproteobacteria,2K2GE@204457|Sphingomonadales	204457|Sphingomonadales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRD2_k127_2672568_3	392499.Swit_3968	1.06e-217	695.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K07A@204457|Sphingomonadales	204457|Sphingomonadales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PilZ
SRD2_k127_2672568_6	633149.Bresu_1163	7.239e-180	574.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TQVP@28211|Alphaproteobacteria,2KIDT@204458|Caulobacterales	204458|Caulobacterales	EGP	Sugar (and other) transporter	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
SRD2_k127_2672568_5	1123267.JONN01000002_gene68	6.39e-194	614.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,2K1AN@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRD2_k127_2672568_2	1123269.NX02_11060	3.884e-229	715.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2TQUS@28211|Alphaproteobacteria,2K1QA@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
SRD2_k127_2672568_18	391625.PPSIR1_24544	4.408e-57	212.0	COG3239@1|root,COG3239@2|Bacteria,1MW29@1224|Proteobacteria,4302Z@68525|delta/epsilon subdivisions,2WVE0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Fatty acid desaturase	-	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase
SRD2_k127_2672568_15	366602.Caul_1957	9.989e-78	273.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2TQJJ@28211|Alphaproteobacteria,2KF24@204458|Caulobacterales	204458|Caulobacterales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRD2_k127_2672568_22	13690.CP98_02405	1.231e-17	89.0	2EUEA@1|root,33MWN@2|Bacteria,1NYM7@1224|Proteobacteria,2UT87@28211|Alphaproteobacteria,2KAMX@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2672568_1	1112214.AHIS01000047_gene2177	0.0	1052.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TQMV@28211|Alphaproteobacteria,2K0W1@204457|Sphingomonadales	204457|Sphingomonadales	G	Glucose dehydrogenase	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
SRD2_k127_2672568_7	1219049.SP5_006_00080	6.389e-169	543.0	COG1680@1|root,COG1680@2|Bacteria,1R8N7@1224|Proteobacteria,2UCNR@28211|Alphaproteobacteria,2K0VY@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRD2_k127_2682554_5	1123267.JONN01000001_gene1284	1.113e-19	90.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2TS6I@28211|Alphaproteobacteria,2K1PI@204457|Sphingomonadales	204457|Sphingomonadales	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRD2_k127_2682554_1	1123267.JONN01000001_gene1285	1.88e-143	477.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2TRYU@28211|Alphaproteobacteria,2K0KV@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
SRD2_k127_2682554_2	1123267.JONN01000001_gene1287	5.911e-95	328.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2TT7W@28211|Alphaproteobacteria,2K1AX@204457|Sphingomonadales	204457|Sphingomonadales	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRD2_k127_2682554_4	1123267.JONN01000001_gene1313	1.976e-45	169.0	COG3324@1|root,COG3324@2|Bacteria,1N0AD@1224|Proteobacteria,2UD6F@28211|Alphaproteobacteria,2KDBW@204457|Sphingomonadales	204457|Sphingomonadales	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRD2_k127_2682554_0	1123267.JONN01000001_gene1316	4.303e-214	674.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRSU@28211|Alphaproteobacteria,2K09A@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRD2_k127_2682554_3	392499.Swit_3212	2.007e-92	306.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,2K0JS@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRD2_k127_272378_29	629773.AORY01000004_gene246	4.765e-06	50.0	2AFT8@1|root,315VF@2|Bacteria,1RAPJ@1224|Proteobacteria,2U6M6@28211|Alphaproteobacteria,2K2CZ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_272378_9	1123267.JONN01000001_gene577	2.629e-121	403.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2U103@28211|Alphaproteobacteria,2K0W4@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRD2_k127_272378_12	1123267.JONN01000001_gene576	5.99e-112	366.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2TSPC@28211|Alphaproteobacteria,2KD3G@204457|Sphingomonadales	204457|Sphingomonadales	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRD2_k127_272378_15	1090318.ATTI01000001_gene1542	5.175e-104	353.0	COG1301@1|root,COG1301@2|Bacteria,1MVID@1224|Proteobacteria,2TUR0@28211|Alphaproteobacteria,2K09V@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
SRD2_k127_272378_16	392499.Swit_4519	4.959e-74	258.0	COG4798@1|root,COG4798@2|Bacteria,1RHGZ@1224|Proteobacteria,2U69N@28211|Alphaproteobacteria,2KDKH@204457|Sphingomonadales	204457|Sphingomonadales	S	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,PCMT
SRD2_k127_272378_19	1122604.JONR01000002_gene1619	4.676e-60	216.0	2919Q@1|root,32TZW@2|Bacteria,1Q71M@1224|Proteobacteria,1SIND@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_272378_18	331869.BAL199_05439	1.782e-62	218.0	COG3791@1|root,COG3791@2|Bacteria,1RFBP@1224|Proteobacteria,2U7YA@28211|Alphaproteobacteria,4BQZ3@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRD2_k127_272378_2	1123267.JONN01000001_gene1971	6.687e-199	634.0	COG1231@1|root,COG1231@2|Bacteria,1MWPH@1224|Proteobacteria,2U05G@28211|Alphaproteobacteria,2K26X@204457|Sphingomonadales	204457|Sphingomonadales	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRD2_k127_272378_21	1123267.JONN01000001_gene574	4.863e-49	183.0	COG1633@1|root,COG1633@2|Bacteria,1RJUG@1224|Proteobacteria,2UATR@28211|Alphaproteobacteria,2K5EA@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF2383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2383
SRD2_k127_272378_14	1123267.JONN01000002_gene197	9.981e-108	353.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,2TSZI@28211|Alphaproteobacteria,2K0QV@204457|Sphingomonadales	204457|Sphingomonadales	H	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRD2_k127_272378_13	1123267.JONN01000002_gene196	1.106e-110	375.0	COG4529@1|root,COG4529@2|Bacteria,1MU3U@1224|Proteobacteria,2TUBM@28211|Alphaproteobacteria,2K079@204457|Sphingomonadales	204457|Sphingomonadales	S	FAD-NAD(P)-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_9
SRD2_k127_272378_23	1090319.KE386571_gene415	1.648e-38	147.0	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2UBTA@28211|Alphaproteobacteria,2K54Q@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1178
SRD2_k127_272378_11	1123267.JONN01000002_gene194	6.074e-120	390.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2TRGZ@28211|Alphaproteobacteria,2K16U@204457|Sphingomonadales	204457|Sphingomonadales	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
SRD2_k127_272378_26	392499.Swit_0558	4.871e-28	116.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2UFM1@28211|Alphaproteobacteria,2K5VT@204457|Sphingomonadales	204457|Sphingomonadales	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
SRD2_k127_272378_22	1123267.JONN01000002_gene191	3.172e-43	171.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2TRFS@28211|Alphaproteobacteria,2K0V6@204457|Sphingomonadales	204457|Sphingomonadales	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRD2_k127_272378_5	1123267.JONN01000002_gene189	1.092e-161	528.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2TTU7@28211|Alphaproteobacteria,2K1IX@204457|Sphingomonadales	204457|Sphingomonadales	S	peptidase M48, Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M48
SRD2_k127_272378_6	1123269.NX02_10825	5.246e-152	485.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2TR6V@28211|Alphaproteobacteria,2K0BW@204457|Sphingomonadales	204457|Sphingomonadales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SRD2_k127_272378_10	1123267.JONN01000001_gene1261	2.965e-120	399.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2TRAA@28211|Alphaproteobacteria,2K25K@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRD2_k127_272378_4	1123267.JONN01000001_gene1262	2.603e-172	561.0	2BWFC@1|root,33R2I@2|Bacteria,1R42X@1224|Proteobacteria,2U4BF@28211|Alphaproteobacteria,2K0XT@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_272378_17	1123267.JONN01000001_gene1264	1.249e-64	227.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,2K4PP@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRD2_k127_272378_1	745310.G432_01695	1.515e-207	662.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,2K1PS@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
SRD2_k127_272378_24	579138.Zymop_0628	2.423e-29	124.0	COG0822@1|root,COG0822@2|Bacteria,1RDGB@1224|Proteobacteria,2U74A@28211|Alphaproteobacteria,2K54B@204457|Sphingomonadales	204457|Sphingomonadales	C	NifU homolog involved in Fe-S cluster formation	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
SRD2_k127_272378_3	1123267.JONN01000001_gene1268	1.108e-194	619.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2TQQ1@28211|Alphaproteobacteria,2K19T@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRD2_k127_272378_20	1123267.JONN01000001_gene1269	4.714e-51	186.0	COG1286@1|root,COG1286@2|Bacteria,1REF7@1224|Proteobacteria,2VA4D@28211|Alphaproteobacteria,2K52S@204457|Sphingomonadales	204457|Sphingomonadales	S	Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
SRD2_k127_272378_7	999541.bgla_1g30870	2.291e-148	483.0	COG0477@1|root,COG0477@2|Bacteria,1MWUR@1224|Proteobacteria,2VMD4@28216|Betaproteobacteria,1K2DY@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08169	-	-	-	-	ko00000,ko02000	2.A.1.3.17	-	-	MFS_1
SRD2_k127_272378_8	1545915.JROG01000003_gene1229	1.022e-143	465.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2TRRT@28211|Alphaproteobacteria,2K121@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
SRD2_k127_272378_0	1123267.JONN01000001_gene1270	6.839e-227	709.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2TS6F@28211|Alphaproteobacteria,2K1F3@204457|Sphingomonadales	204457|Sphingomonadales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
SRD2_k127_2782149_0	1123267.JONN01000002_gene104	0.0	1087.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2TQRQ@28211|Alphaproteobacteria,2K0IA@204457|Sphingomonadales	204457|Sphingomonadales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRD2_k127_2782149_1	1123267.JONN01000002_gene93	1.801e-233	734.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2KEG2@204457|Sphingomonadales	204457|Sphingomonadales	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
SRD2_k127_2837644_18	1502850.FG91_03472	9.428e-35	135.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2TUF7@28211|Alphaproteobacteria,2K1B9@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_tran_2,CDP-OH_P_transf
SRD2_k127_2837644_3	1123267.JONN01000001_gene1146	1.148e-143	459.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2TRXE@28211|Alphaproteobacteria,2K0DP@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRD2_k127_2837644_5	745310.G432_04285	2.713e-134	434.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2TQM0@28211|Alphaproteobacteria,2JZY1@204457|Sphingomonadales	204457|Sphingomonadales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRD2_k127_2837644_7	1346791.M529_11425	1.153e-121	394.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2TQYN@28211|Alphaproteobacteria,2K1B1@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRD2_k127_2837644_10	317655.Sala_1957	2.177e-84	282.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2U5B2@28211|Alphaproteobacteria,2K00Z@204457|Sphingomonadales	204457|Sphingomonadales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRD2_k127_2837644_9	1123267.JONN01000001_gene1150	1.336e-93	315.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TTVJ@28211|Alphaproteobacteria,2K0JM@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRD2_k127_2837644_12	1123267.JONN01000001_gene1151	2.803e-71	247.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2U9ED@28211|Alphaproteobacteria,2K1ET@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRD2_k127_2837644_4	1335760.ASTG01000001_gene3032	3.599e-141	462.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2TSD1@28211|Alphaproteobacteria,2K0YA@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRD2_k127_2837644_6	1123267.JONN01000001_gene1153	8.336e-131	427.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2TQXJ@28211|Alphaproteobacteria,2K0AZ@204457|Sphingomonadales	204457|Sphingomonadales	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
SRD2_k127_2837644_0	1123267.JONN01000001_gene1154	0.0	1089.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria,2K0GI@204457|Sphingomonadales	204457|Sphingomonadales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRD2_k127_2837644_14	1096930.L284_19455	7.55e-45	170.0	COG2825@1|root,COG2825@2|Bacteria,1NNT2@1224|Proteobacteria,2UM5J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Outer membrane protein (OmpH-like)	-	-	-	-	-	-	-	-	-	-	-	-	OmpH
SRD2_k127_2837644_11	745310.G432_04240	1.71e-73	256.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2U7G4@28211|Alphaproteobacteria,2K4JA@204457|Sphingomonadales	204457|Sphingomonadales	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRD2_k127_2837644_1	1123267.JONN01000001_gene1160	1.098e-174	567.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2TT3G@28211|Alphaproteobacteria,2K12C@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
SRD2_k127_2837644_15	945713.IALB_2304	2.632e-41	162.0	2CBKC@1|root,32RTJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2837644_17	1123267.JONN01000001_gene1161	3.655e-37	142.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2UBSC@28211|Alphaproteobacteria,2K643@204457|Sphingomonadales	204457|Sphingomonadales	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRD2_k127_2837644_16	311402.Avi_1793	9.031e-38	151.0	COG1670@1|root,COG1670@2|Bacteria,1RHBD@1224|Proteobacteria,2U80N@28211|Alphaproteobacteria,4BDWY@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRD2_k127_2837644_2	392499.Swit_4521	4.023e-163	535.0	COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,2TUBP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
SRD2_k127_2837644_13	392499.Swit_4520	6.614e-67	233.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2U6EM@28211|Alphaproteobacteria,2K6NB@204457|Sphingomonadales	204457|Sphingomonadales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRD2_k127_2837644_8	1123267.JONN01000002_gene354	6.537e-106	345.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2TSAC@28211|Alphaproteobacteria,2K030@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD2_k127_2846105_8	864069.MicloDRAFT_00011390	1.475e-28	121.0	2F5FH@1|root,33Y16@2|Bacteria,1NX2C@1224|Proteobacteria,2USI2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2846105_1	420324.KI912074_gene5900	2.116e-205	654.0	COG2723@1|root,COG2723@2|Bacteria,1MWU7@1224|Proteobacteria,2TT4I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the glycosyl hydrolase 1 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_1
SRD2_k127_2846105_3	1172179.AUKV01000009_gene4494	2.623e-133	436.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2846105_2	1282360.ABAC460_07210	1.419e-135	451.0	COG4796@1|root,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria	1224|Proteobacteria	U	type II and III secretion system protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	STN,Secretin,Secretin_N
SRD2_k127_2846105_10	1549858.MC45_02295	2.869e-13	76.0	COG3847@1|root,COG3847@2|Bacteria,1Q1G3@1224|Proteobacteria,2V11R@28211|Alphaproteobacteria,2K7TI@204457|Sphingomonadales	204457|Sphingomonadales	U	Flp pilus assembly protein, pilin Flp	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
SRD2_k127_2846105_0	1123267.JONN01000001_gene1579	5.172e-274	857.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,2K0XK@204457|Sphingomonadales	204457|Sphingomonadales	M	Penicillin-binding Protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRD2_k127_2846105_4	1123267.JONN01000001_gene1578	2.359e-132	437.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TWWQ@28211|Alphaproteobacteria,2KEK8@204457|Sphingomonadales	204457|Sphingomonadales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
SRD2_k127_2846105_6	685778.AORL01000010_gene2986	2.133e-53	190.0	2DMJE@1|root,32RYR@2|Bacteria,1N7PS@1224|Proteobacteria,2UFEW@28211|Alphaproteobacteria,2K57K@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4112)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4112
SRD2_k127_2846105_7	1081640.AGFU01000026_gene2674	7.388e-34	139.0	COG0810@1|root,COG0810@2|Bacteria,1NB5F@1224|Proteobacteria,2USI1@28211|Alphaproteobacteria,2K2ZM@204457|Sphingomonadales	204457|Sphingomonadales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRD2_k127_2846105_9	1549858.MC45_13515	3.831e-17	84.0	2AN25@1|root,31CZQ@2|Bacteria,1R3N2@1224|Proteobacteria,2U049@28211|Alphaproteobacteria,2K6MC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2846105_5	702113.PP1Y_AT34984	6.47e-128	413.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TTI9@28211|Alphaproteobacteria,2K29S@204457|Sphingomonadales	204457|Sphingomonadales	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
SRD2_k127_2849085_4	1234364.AMSF01000079_gene1847	3.22e-247	779.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,1RZK1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRD2_k127_2849085_5	861299.J421_1502	5.751e-243	792.0	COG4447@1|root,COG4447@2|Bacteria,1ZUS1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRD2_k127_2849085_0	1248916.ANFY01000009_gene99	0.0	1408.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2U0UY@28211|Alphaproteobacteria,2KDZF@204457|Sphingomonadales	204457|Sphingomonadales	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRD2_k127_2849085_9	1248916.ANFY01000009_gene98	5.567e-82	282.0	COG2834@1|root,COG2834@2|Bacteria,1R8JU@1224|Proteobacteria	1224|Proteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
SRD2_k127_2849085_11	1304275.C41B8_00915	1.492e-73	264.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST,RimK
SRD2_k127_2849085_13	1211115.ALIQ01000021_gene4564	2.045e-60	214.0	COG5502@1|root,COG5502@2|Bacteria,1NB8V@1224|Proteobacteria,2U9GZ@28211|Alphaproteobacteria,3NBWK@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
SRD2_k127_2849085_3	1123267.JONN01000002_gene5	2.644e-267	833.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2TRNT@28211|Alphaproteobacteria,2K008@204457|Sphingomonadales	204457|Sphingomonadales	U	Flp pilus assembly protein, ATPase CpaF	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRD2_k127_2849085_10	426117.M446_2760	1.069e-77	282.0	COG2311@1|root,COG2311@2|Bacteria,1R8CP@1224|Proteobacteria,2TQPJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2849085_8	35703.DQ02_16640	1.445e-84	297.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_11
SRD2_k127_2849085_16	391595.RLO149_c044350	4.215e-24	113.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_23
SRD2_k127_2849085_14	877421.AUJT01000002_gene1207	2.797e-57	213.0	COG0673@1|root,COG0673@2|Bacteria,1TQFW@1239|Firmicutes,24BIG@186801|Clostridia,27KU6@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRD2_k127_2849085_18	1082933.MEA186_12918	2.508e-13	75.0	2ESZ6@1|root,33KHF@2|Bacteria,1NQAZ@1224|Proteobacteria	1224|Proteobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRD2_k127_2849085_6	876269.ARWA01000001_gene2482	1.652e-133	437.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,2TVY5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD2_k127_2849085_15	1123267.JONN01000002_gene7	3.6e-29	118.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2UBXX@28211|Alphaproteobacteria,2K5WN@204457|Sphingomonadales	204457|Sphingomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02113,ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
SRD2_k127_2849085_17	864069.MicloDRAFT_00017450	2.826e-23	99.0	2DPZ8@1|root,3341I@2|Bacteria,1N7WK@1224|Proteobacteria,2UHE6@28211|Alphaproteobacteria,1JVNU@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2849085_2	1123267.JONN01000002_gene8	1.316e-276	856.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2TRGP@28211|Alphaproteobacteria,2K03H@204457|Sphingomonadales	204457|Sphingomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRD2_k127_2849085_7	1123267.JONN01000002_gene9	1.847e-124	404.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2TR11@28211|Alphaproteobacteria,2K0A5@204457|Sphingomonadales	204457|Sphingomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRD2_k127_2849085_1	1123267.JONN01000002_gene10	3.103e-297	915.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2TQYK@28211|Alphaproteobacteria,2K08A@204457|Sphingomonadales	204457|Sphingomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRD2_k127_2849085_12	1123267.JONN01000002_gene11	4.699e-67	232.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2U5IC@28211|Alphaproteobacteria,2K4UU@204457|Sphingomonadales	204457|Sphingomonadales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRD2_k127_2876412_9	1123267.JONN01000002_gene72	4.861e-116	376.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2TQXZ@28211|Alphaproteobacteria,2K0F4@204457|Sphingomonadales	204457|Sphingomonadales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRD2_k127_2876412_14	1123267.JONN01000002_gene73	1.047e-56	211.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2U74V@28211|Alphaproteobacteria,2K4GE@204457|Sphingomonadales	204457|Sphingomonadales	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRD2_k127_2876412_18	1123267.JONN01000002_gene74	8.812e-13	69.0	COG5570@1|root,COG5570@2|Bacteria,1NGRE@1224|Proteobacteria,2UJAX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Small protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
SRD2_k127_2876412_13	1123267.JONN01000002_gene76	3.47e-60	212.0	COG5317@1|root,COG5317@2|Bacteria,1RJIA@1224|Proteobacteria,2U9ID@28211|Alphaproteobacteria,2K5B1@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1465)	-	-	-	ko:K13592	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	DUF1465
SRD2_k127_2876412_5	1123267.JONN01000002_gene80	6.921e-153	488.0	COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,2TS5U@28211|Alphaproteobacteria,2K0V5@204457|Sphingomonadales	204457|Sphingomonadales	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
SRD2_k127_2876412_6	279238.Saro_3151	5.074e-149	478.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2TSIP@28211|Alphaproteobacteria,2K0VH@204457|Sphingomonadales	204457|Sphingomonadales	M	epimerase dehydratase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRD2_k127_2876412_0	161528.ED21_21814	0.0	1656.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2K2G6@204457|Sphingomonadales	204457|Sphingomonadales	EQ	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
SRD2_k127_2876412_11	383381.EH30_04555	2.065e-80	280.0	COG3819@1|root,COG3819@2|Bacteria,1MWFM@1224|Proteobacteria,2U5DR@28211|Alphaproteobacteria,2K0TR@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF969
SRD2_k127_2876412_10	685035.ADAE01000008_gene2928	4.379e-113	377.0	COG3817@1|root,COG3817@2|Bacteria,1MXGD@1224|Proteobacteria,2TUDC@28211|Alphaproteobacteria,2K1SX@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF979
SRD2_k127_2876412_8	1207055.C100_20960	5.128e-135	438.0	2C57D@1|root,2Z7RS@2|Bacteria,1MX6G@1224|Proteobacteria,2TTDU@28211|Alphaproteobacteria,2K0FT@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
SRD2_k127_2876412_16	1123269.NX02_28315	9.236e-33	140.0	COG3491@1|root,COG3491@2|Bacteria,1MUNT@1224|Proteobacteria,2TU3Y@28211|Alphaproteobacteria,2K1Y3@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
SRD2_k127_2876412_4	1114964.L485_21815	3.649e-154	507.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TUFK@28211|Alphaproteobacteria,2K0NW@204457|Sphingomonadales	204457|Sphingomonadales	M	RND efflux system, outer membrane lipoprotein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
SRD2_k127_2876412_1	194867.ALBQ01000012_gene711	0.0	1450.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2K02H@204457|Sphingomonadales	204457|Sphingomonadales	V	Efflux pump membrane transporter	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
SRD2_k127_2876412_7	1449076.JOOE01000004_gene616	8.095e-146	473.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2TSW4@28211|Alphaproteobacteria,2K1BG@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD,HlyD_D23
SRD2_k127_2876412_12	1121124.JNIX01000001_gene1006	1.617e-77	278.0	COG2382@1|root,COG2382@2|Bacteria,1QZM0@1224|Proteobacteria,2TY9P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRD2_k127_2876412_3	1123267.JONN01000001_gene499	1.69e-217	685.0	COG0654@1|root,COG0654@2|Bacteria,1NSGN@1224|Proteobacteria,2UPGQ@28211|Alphaproteobacteria,2KEGZ@204457|Sphingomonadales	204457|Sphingomonadales	CH	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
SRD2_k127_2876412_2	685778.AORL01000021_gene948	0.0	1053.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,2U1U0@28211|Alphaproteobacteria,2K175@204457|Sphingomonadales	204457|Sphingomonadales	G	Galactose mutarotase-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
SRD2_k127_2876412_15	1123267.JONN01000001_gene502	8.989e-50	181.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,2TRS3@28211|Alphaproteobacteria,2K1CG@204457|Sphingomonadales	204457|Sphingomonadales	G	Alpha-amylase domain	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
SRD2_k127_2890548_23	1123267.JONN01000002_gene251	4.698e-10	64.0	COG2234@1|root,COG2234@2|Bacteria,1R56X@1224|Proteobacteria,2U2G7@28211|Alphaproteobacteria,2K2WC@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRD2_k127_2890548_12	1449076.JOOE01000003_gene3197	1.572e-75	263.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2TRUD@28211|Alphaproteobacteria,2K414@204457|Sphingomonadales	204457|Sphingomonadales	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
SRD2_k127_2890548_0	685778.AORL01000021_gene430	0.0	1136.0	COG1506@1|root,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,2TRVE@28211|Alphaproteobacteria,2K0U1@204457|Sphingomonadales	204457|Sphingomonadales	E	peptidase S9	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
SRD2_k127_2890548_16	1123269.NX02_13010	2.864e-54	199.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2U9DF@28211|Alphaproteobacteria,2K4GC@204457|Sphingomonadales	204457|Sphingomonadales	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRD2_k127_2890548_5	1123267.JONN01000002_gene249	2.411e-129	417.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2TSIZ@28211|Alphaproteobacteria,2JZVZ@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRD2_k127_2890548_6	1123267.JONN01000002_gene247	3.778e-127	414.0	COG0492@1|root,COG0492@2|Bacteria,1MVWS@1224|Proteobacteria,2TU6F@28211|Alphaproteobacteria,2K1CC@204457|Sphingomonadales	204457|Sphingomonadales	O	Thioredoxin reductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
SRD2_k127_2890548_15	1123267.JONN01000002_gene312	6.234e-60	211.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2U9UT@28211|Alphaproteobacteria,2K4H2@204457|Sphingomonadales	204457|Sphingomonadales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRD2_k127_2890548_18	1537715.JQFJ01000002_gene2320	4.859e-49	194.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2U94X@28211|Alphaproteobacteria,2K4I6@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRD2_k127_2890548_1	1123267.JONN01000002_gene310	2.311e-241	753.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2TQSW@28211|Alphaproteobacteria,2K1DQ@204457|Sphingomonadales	204457|Sphingomonadales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRD2_k127_2890548_19	1123267.JONN01000001_gene1125	1.327e-30	126.0	2BPFV@1|root,32I85@2|Bacteria,1Q8G2@1224|Proteobacteria,2VEP2@28211|Alphaproteobacteria,2K6XS@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2890548_26	1242864.D187_007808	7.138e-07	53.0	COG0189@1|root,COG0189@2|Bacteria,1R5VK@1224|Proteobacteria,42UP6@68525|delta/epsilon subdivisions,2WVQB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	HJ	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2890548_8	1123267.JONN01000001_gene1124	2.606e-121	394.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2TUF2@28211|Alphaproteobacteria,2K1PV@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRD2_k127_2890548_7	745310.G432_03105	6.683e-122	406.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,2TRYD@28211|Alphaproteobacteria,2K0WZ@204457|Sphingomonadales	204457|Sphingomonadales	J	2-methylthioadenine	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
SRD2_k127_2890548_2	1123267.JONN01000001_gene1123	5.492e-161	516.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2TS0M@28211|Alphaproteobacteria,2K03J@204457|Sphingomonadales	204457|Sphingomonadales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRD2_k127_2890548_14	1346791.M529_07595	4.142e-64	226.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2U74X@28211|Alphaproteobacteria,2K4N8@204457|Sphingomonadales	204457|Sphingomonadales	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
SRD2_k127_2890548_4	1121123.AUAO01000003_gene2222	2.341e-131	431.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,2KFAS@204458|Caulobacterales	204458|Caulobacterales	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD2_k127_2890548_9	1035191.HMPREF0185_00814	3.482e-103	356.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2TQSY@28211|Alphaproteobacteria,2KF5W@204458|Caulobacterales	204458|Caulobacterales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRD2_k127_2890548_3	1384056.N787_12110	2.501e-150	498.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,1X45I@135614|Xanthomonadales	135614|Xanthomonadales	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRD2_k127_2890548_10	1449076.JOOE01000002_gene899	4.696e-90	301.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2TU3T@28211|Alphaproteobacteria,2K112@204457|Sphingomonadales	204457|Sphingomonadales	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRD2_k127_2890548_13	1449076.JOOE01000002_gene900	1.005e-74	256.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,2U7B1@28211|Alphaproteobacteria,2K410@204457|Sphingomonadales	204457|Sphingomonadales	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
SRD2_k127_2890548_22	1121949.AQXT01000002_gene614	7.329e-19	93.0	COG0457@1|root,COG0457@2|Bacteria,1MYIE@1224|Proteobacteria,2UAH0@28211|Alphaproteobacteria,43Y33@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
SRD2_k127_2890548_11	1123267.JONN01000001_gene1429	9.371e-78	271.0	COG3577@1|root,COG3577@2|Bacteria,1MYAD@1224|Proteobacteria,2U9RE@28211|Alphaproteobacteria,2K4GD@204457|Sphingomonadales	204457|Sphingomonadales	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,gag-asp_proteas
SRD2_k127_2890548_17	1123267.JONN01000001_gene1430	6.439e-54	200.0	2AKT1@1|root,31BK2@2|Bacteria,1NXBB@1224|Proteobacteria,2UTRK@28211|Alphaproteobacteria,2K5KP@204457|Sphingomonadales	204457|Sphingomonadales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
SRD2_k127_2890548_20	1120705.FG95_01143	1.5e-30	126.0	COG2813@1|root,COG2813@2|Bacteria,1RHAE@1224|Proteobacteria,2U5V5@28211|Alphaproteobacteria,2K42K@204457|Sphingomonadales	204457|Sphingomonadales	J	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
SRD2_k127_2890548_27	272134.KB731324_gene1612	6.179e-06	55.0	COG1848@1|root,COG1848@2|Bacteria,1G6WR@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRD2_k127_2977151_31	391595.RLO149_c017560	4.469e-13	69.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria,2P2YR@2433|Roseobacter	28211|Alphaproteobacteria	L	COG2826 Transposase and inactivated derivatives, IS30 family	-	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
SRD2_k127_2977151_7	1088721.NSU_0986	5.985e-135	443.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	BCSC_C,DUF560,TPR_16,TPR_19,TPR_8
SRD2_k127_2977151_25	1247963.JPHU01000010_gene2209	1.918e-24	120.0	COG3710@1|root,COG3710@2|Bacteria,1QTZ6@1224|Proteobacteria,2TZTT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRD2_k127_2977151_3	392499.Swit_3144	5.521e-252	811.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria,2JZUI@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRD2_k127_2977151_2	1382303.JPOM01000001_gene2110	6.788e-268	841.0	COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,2U2MN@28211|Alphaproteobacteria,2KF5T@204458|Caulobacterales	204458|Caulobacterales	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
SRD2_k127_2977151_27	279238.Saro_2779	8.987e-23	105.0	2EHBD@1|root,33B38@2|Bacteria,1N20E@1224|Proteobacteria,2UDRX@28211|Alphaproteobacteria,2KDND@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
SRD2_k127_2977151_1	1267533.KB906739_gene2494	1.018e-275	860.0	COG3533@1|root,COG3533@2|Bacteria,3Y6PC@57723|Acidobacteria,2JKG6@204432|Acidobacteriia	204432|Acidobacteriia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
SRD2_k127_2977151_26	1449049.JONW01000002_gene2488	3.747e-23	110.0	COG0726@1|root,COG0726@2|Bacteria,1RBMV@1224|Proteobacteria,2URX3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRD2_k127_2977151_12	383381.EH30_11565	2.426e-109	366.0	COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,2U2XC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
SRD2_k127_2977151_5	383381.EH30_11560	3.654e-181	578.0	COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,2UP2I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2977151_24	443598.AUFA01000004_gene5431	5.572e-29	124.0	COG3467@1|root,COG3467@2|Bacteria,1RAZD@1224|Proteobacteria,2TXIF@28211|Alphaproteobacteria,3K6W8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRD2_k127_2977151_28	443255.SCLAV_2037	6.38e-21	101.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
SRD2_k127_2977151_21	1449076.JOOE01000001_gene2852	4.376e-32	127.0	2AMM4@1|root,32GS6@2|Bacteria,1RJBC@1224|Proteobacteria,2UADA@28211|Alphaproteobacteria,2KDIC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2977151_20	1282360.ABAC460_23415	1.764e-42	163.0	COG0457@1|root,COG0457@2|Bacteria,1N9D5@1224|Proteobacteria,2UIQ4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2977151_19	485913.Krac_11463	2.101e-45	178.0	COG1266@1|root,COG1266@2|Bacteria,2G8XJ@200795|Chloroflexi	200795|Chloroflexi	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRD2_k127_2977151_16	1282360.ABAC460_05630	3.39e-73	256.0	28JPA@1|root,2Z9FC@2|Bacteria,1PN1F@1224|Proteobacteria,2TSKX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2977151_13	1123267.JONN01000001_gene1877	1.643e-102	344.0	COG0560@1|root,COG0560@2|Bacteria,1P4TB@1224|Proteobacteria,2UHTZ@28211|Alphaproteobacteria,2K3BN@204457|Sphingomonadales	204457|Sphingomonadales	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRD2_k127_2977151_14	1123267.JONN01000001_gene1876	3.155e-75	270.0	COG0746@1|root,COG0746@2|Bacteria,1QWF1@1224|Proteobacteria,2TXF5@28211|Alphaproteobacteria,2KEHV@204457|Sphingomonadales	204457|Sphingomonadales	H	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
SRD2_k127_2977151_8	1123267.JONN01000001_gene1875	1.621e-132	432.0	COG0558@1|root,COG0558@2|Bacteria,1MYE7@1224|Proteobacteria,2TSMC@28211|Alphaproteobacteria,2K2MN@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
SRD2_k127_2977151_6	1123267.JONN01000001_gene1874	8.199e-163	519.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,2K10W@204457|Sphingomonadales	204457|Sphingomonadales	Q	ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRD2_k127_2977151_9	1123267.JONN01000001_gene1873	3.47e-125	421.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,2K11G@204457|Sphingomonadales	204457|Sphingomonadales	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRD2_k127_2977151_10	1123267.JONN01000001_gene1872	2.403e-117	385.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2U1JN@28211|Alphaproteobacteria,2K12E@204457|Sphingomonadales	204457|Sphingomonadales	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRD2_k127_2977151_17	1123267.JONN01000001_gene1871	2.44e-54	200.0	COG3218@1|root,COG3218@2|Bacteria,1RKTW@1224|Proteobacteria,2UAXY@28211|Alphaproteobacteria,2K5KR@204457|Sphingomonadales	204457|Sphingomonadales	S	transport system auxiliary component	linN	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
SRD2_k127_2977151_0	745310.G432_15180	0.0	1127.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria,2K072@204457|Sphingomonadales	204457|Sphingomonadales	E	aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
SRD2_k127_2977151_22	1123267.JONN01000001_gene1946	2.082e-30	121.0	COG3798@1|root,COG3798@2|Bacteria,1N2FJ@1224|Proteobacteria,2UC84@28211|Alphaproteobacteria,2K6QA@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein conserved in bacteria (DUF2171)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2171
SRD2_k127_2977151_18	279238.Saro_3152	1.356e-50	183.0	2D8VC@1|root,32TS1@2|Bacteria,1MZWT@1224|Proteobacteria,2UEVN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2977151_15	161528.ED21_18302	2.372e-74	260.0	28NPB@1|root,2ZBP9@2|Bacteria,1R3HY@1224|Proteobacteria	1224|Proteobacteria	S	Sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
SRD2_k127_2977151_32	298653.Franean1_6539	1.111e-12	74.0	COG1525@1|root,COG1525@2|Bacteria	2|Bacteria	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur,SNase
SRD2_k127_2977151_4	314266.SKA58_14407	6.636e-212	661.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2TS3X@28211|Alphaproteobacteria,2K1H7@204457|Sphingomonadales	204457|Sphingomonadales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
SRD2_k127_2977151_23	1449076.JOOE01000003_gene3316	2.747e-29	123.0	2EG8Z@1|root,33A0S@2|Bacteria,1NKBI@1224|Proteobacteria,2UN0S@28211|Alphaproteobacteria,2K67X@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_2977151_11	685778.AORL01000009_gene3262	1.1e-109	362.0	COG2234@1|root,COG2234@2|Bacteria,1R6BQ@1224|Proteobacteria,2U2SM@28211|Alphaproteobacteria,2K3NR@204457|Sphingomonadales	204457|Sphingomonadales	S	Transferrin receptor-like dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28,TFR_dimer
SRD2_k127_299276_3	1114964.L485_20920	1.563e-102	341.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2TRV3@28211|Alphaproteobacteria,2K21F@204457|Sphingomonadales	204457|Sphingomonadales	T	Phosphate starvation-inducible protein PhoH	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRD2_k127_299276_0	383381.EH30_08350	4.413e-197	623.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2TQN6@28211|Alphaproteobacteria,2K1NH@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRD2_k127_299276_9	46429.BV95_00032	1.753e-52	196.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2TT8Q@28211|Alphaproteobacteria,2K221@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRD2_k127_299276_5	627192.SLG_29410	3.928e-73	248.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2U6ZS@28211|Alphaproteobacteria,2K3Z2@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRD2_k127_299276_6	1123267.JONN01000001_gene815	7.052e-67	231.0	COG4957@1|root,COG4957@2|Bacteria,1RGUW@1224|Proteobacteria,2U99M@28211|Alphaproteobacteria,2K4EY@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	ROS_MUCR
SRD2_k127_299276_10	685778.AORL01000010_gene2626	2.5e-38	153.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2UF5C@28211|Alphaproteobacteria,2K616@204457|Sphingomonadales	204457|Sphingomonadales	K	Acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
SRD2_k127_299276_8	1123267.JONN01000001_gene817	1.815e-56	205.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2TTM2@28211|Alphaproteobacteria,2K59A@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidase M22	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M22
SRD2_k127_299276_4	1123267.JONN01000001_gene866	1.879e-83	282.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria,2K0IN@204457|Sphingomonadales	204457|Sphingomonadales	O	COG0694 Thioredoxin-like proteins and domains	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
SRD2_k127_299276_7	1123267.JONN01000001_gene1312	9.73e-63	223.0	COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,2U9DR@28211|Alphaproteobacteria,2K5R6@204457|Sphingomonadales	204457|Sphingomonadales	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
SRD2_k127_299276_11	1123267.JONN01000001_gene1311	4.46e-26	114.0	COG3909@1|root,COG3909@2|Bacteria,1Q594@1224|Proteobacteria,2UG98@28211|Alphaproteobacteria,2K6Z1@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome C'	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
SRD2_k127_299276_1	1123267.JONN01000001_gene1310	9.498e-125	416.0	COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,2UVAZ@28211|Alphaproteobacteria,2K1F0@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the 3-hydroxyisobutyrate dehydrogenase family	mmsB	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRD2_k127_299276_2	1123267.JONN01000001_gene1309	1.35e-108	354.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,2K12I@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD2_k127_3022912_13	1088721.NSU_3857	6.562e-14	78.0	2AI6K@1|root,318KX@2|Bacteria,1P1HA@1224|Proteobacteria,2UV4H@28211|Alphaproteobacteria,2K74P@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_3022912_3	745310.G432_09735	4.255e-174	561.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2K08H@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRD2_k127_3022912_10	1123267.JONN01000001_gene414	6.76e-111	370.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2TRP4@28211|Alphaproteobacteria,2K1HR@204457|Sphingomonadales	204457|Sphingomonadales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
SRD2_k127_3022912_6	1123269.NX02_29005	1.279e-121	400.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2TRTP@28211|Alphaproteobacteria,2K20N@204457|Sphingomonadales	204457|Sphingomonadales	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
SRD2_k127_3022912_7	1123267.JONN01000001_gene416	1.482e-121	400.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,2K1RH@204457|Sphingomonadales	204457|Sphingomonadales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
SRD2_k127_3022912_12	745310.G432_09715	9.626e-67	235.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2TUIY@28211|Alphaproteobacteria,2K4FQ@204457|Sphingomonadales	204457|Sphingomonadales	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRD2_k127_3022912_4	745310.G432_11815	8.351e-155	506.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2TSAV@28211|Alphaproteobacteria,2K048@204457|Sphingomonadales	204457|Sphingomonadales	S	modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRD2_k127_3022912_9	1123267.JONN01000001_gene419	5.659e-118	388.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2TT3I@28211|Alphaproteobacteria,2K0XU@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRD2_k127_3022912_11	1123267.JONN01000001_gene1836	4.466e-85	289.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2TS0N@28211|Alphaproteobacteria,2K0TB@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRD2_k127_3022912_2	1123267.JONN01000001_gene1837	3.69e-243	756.0	COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,2TRPT@28211|Alphaproteobacteria,2K1IW@204457|Sphingomonadales	204457|Sphingomonadales	H	glutamate--cysteine ligase	-	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
SRD2_k127_3022912_5	1120792.JAFV01000001_gene3721	7.217e-134	435.0	COG2267@1|root,COG2267@2|Bacteria,1QU3E@1224|Proteobacteria,2TVXS@28211|Alphaproteobacteria,36XS6@31993|Methylocystaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	pipch2	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRD2_k127_3022912_1	1123267.JONN01000001_gene1480	2.585e-304	948.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2TS4D@28211|Alphaproteobacteria,2K1S8@204457|Sphingomonadales	204457|Sphingomonadales	S	COG2366 Protein related to penicillin acylase	-	-	-	-	-	-	-	-	-	-	-	-	Penicil_amidase
SRD2_k127_3022912_0	1123267.JONN01000001_gene1839	0.0	1200.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2TRSZ@28211|Alphaproteobacteria,2K046@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRD2_k127_3022912_8	392499.Swit_3981	2.22e-121	398.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,2TRTI@28211|Alphaproteobacteria,2K1JG@204457|Sphingomonadales	204457|Sphingomonadales	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRD2_k127_3022912_14	742823.HMPREF9465_00981	1.271e-10	64.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,4PQGC@995019|Sutterellaceae	28216|Betaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRD2_k127_3073655_0	1123267.JONN01000001_gene447	3.875e-215	675.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2TRT0@28211|Alphaproteobacteria,2K03S@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRD2_k127_3073655_2	1123267.JONN01000001_gene446	2.775e-169	547.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2TSEY@28211|Alphaproteobacteria,2K0YF@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRD2_k127_3073655_1	1123267.JONN01000001_gene445	2.647e-188	595.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2TQSA@28211|Alphaproteobacteria,2K0IS@204457|Sphingomonadales	204457|Sphingomonadales	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRD2_k127_3073655_3	291985.CCSI01000003_gene12	2.528e-21	94.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2TTE8@28211|Alphaproteobacteria,2K1GM@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRD2_k127_3084116_2	1123267.JONN01000002_gene27	2.488e-134	429.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2V929@28211|Alphaproteobacteria,2K9IC@204457|Sphingomonadales	204457|Sphingomonadales	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRD2_k127_3084116_1	1123267.JONN01000002_gene29	2.768e-161	520.0	COG0508@1|root,COG0508@2|Bacteria,1R0J5@1224|Proteobacteria,2U28K@28211|Alphaproteobacteria,2K8XE@204457|Sphingomonadales	204457|Sphingomonadales	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRD2_k127_3084116_3	1123269.NX02_08470	1.12e-102	340.0	COG2129@1|root,COG2129@2|Bacteria,1MVNK@1224|Proteobacteria,2U1YV@28211|Alphaproteobacteria,2K32D@204457|Sphingomonadales	204457|Sphingomonadales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRD2_k127_3084116_4	1121033.AUCF01000003_gene3135	5.586e-90	304.0	2DB86@1|root,2Z7QD@2|Bacteria,1MX4S@1224|Proteobacteria,2TTA6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
SRD2_k127_3084116_5	1476583.DEIPH_ctg079orf0054	7.21e-42	160.0	COG0221@1|root,COG0221@2|Bacteria,1WIM0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRD2_k127_3084116_0	392499.Swit_0037	7.392e-320	993.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2TRBP@28211|Alphaproteobacteria,2K167@204457|Sphingomonadales	204457|Sphingomonadales	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRD2_k127_3084116_6	204669.Acid345_2556	4.214e-40	154.0	COG1228@1|root,COG1228@2|Bacteria,3Y39J@57723|Acidobacteria,2JIMA@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRD2_k127_3107928_1	1144307.PMI04_02580	4.445e-246	769.0	COG2060@1|root,COG2060@2|Bacteria,1MV1K@1224|Proteobacteria,2TSIJ@28211|Alphaproteobacteria,2K0P6@204457|Sphingomonadales	204457|Sphingomonadales	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
SRD2_k127_3107928_0	314266.SKA58_01475	3.38e-316	979.0	COG2216@1|root,COG2216@2|Bacteria,1MU7D@1224|Proteobacteria,2TREM@28211|Alphaproteobacteria,2K0K4@204457|Sphingomonadales	204457|Sphingomonadales	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
SRD2_k127_3107928_2	1123267.JONN01000001_gene1257	4.291e-56	202.0	COG2156@1|root,COG2156@2|Bacteria,1RABG@1224|Proteobacteria,2TSQ7@28211|Alphaproteobacteria,2K2ZB@204457|Sphingomonadales	204457|Sphingomonadales	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	-	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
SRD2_k127_3131437_4	1123267.JONN01000001_gene756	1.087e-152	492.0	COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,2TS9N@28211|Alphaproteobacteria,2K1P6@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	2CSK_N,HATPase_c
SRD2_k127_3131437_5	1123267.JONN01000001_gene757	4.515e-134	428.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2TSV8@28211|Alphaproteobacteria,2K0M9@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD2_k127_3131437_9	1123267.JONN01000001_gene758	6.071e-25	108.0	29288@1|root,2ZPSV@2|Bacteria,1NJAG@1224|Proteobacteria,2UMCR@28211|Alphaproteobacteria,2K6S1@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
SRD2_k127_3131437_0	1123267.JONN01000001_gene759	1.163e-296	919.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TR3X@28211|Alphaproteobacteria,2K0QQ@204457|Sphingomonadales	204457|Sphingomonadales	S	of ABC transporters with duplicated ATPase	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD
SRD2_k127_3131437_2	1123267.JONN01000001_gene764	3.771e-218	685.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2K0MW@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRD2_k127_3131437_1	1123267.JONN01000001_gene765	6.638e-227	722.0	COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,2TXJW@28211|Alphaproteobacteria,2KEK6@204457|Sphingomonadales	204457|Sphingomonadales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c
SRD2_k127_3131437_3	1123267.JONN01000001_gene766	3.865e-182	587.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,2K0AI@204457|Sphingomonadales	204457|Sphingomonadales	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRD2_k127_3131437_7	1123267.JONN01000001_gene767	1.008e-49	193.0	2E21J@1|root,32X9B@2|Bacteria,1N5A7@1224|Proteobacteria,2UF1K@28211|Alphaproteobacteria,2K5FT@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4893)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4893
SRD2_k127_3131437_6	629773.AORY01000012_gene996	3.453e-120	394.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,2K16P@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
SRD2_k127_3131437_8	1114964.L485_15535	8.088e-35	138.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2TRCS@28211|Alphaproteobacteria,2K20W@204457|Sphingomonadales	204457|Sphingomonadales	S	metalloprotease	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRD2_k127_3185289_3	1030157.AFMP01000016_gene2436	3.673e-241	759.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2TRZQ@28211|Alphaproteobacteria,2K0VW@204457|Sphingomonadales	204457|Sphingomonadales	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRD2_k127_3185289_29	1123267.JONN01000001_gene2473	7.986e-48	181.0	2E3B5@1|root,32YAP@2|Bacteria,1N7KQ@1224|Proteobacteria,2UHG1@28211|Alphaproteobacteria,2K43M@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
SRD2_k127_3185289_38	1123267.JONN01000001_gene482	1.929e-26	119.0	2BSC6@1|root,32ME1@2|Bacteria,1PPBT@1224|Proteobacteria,2V1U9@28211|Alphaproteobacteria,2KC1J@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_3185289_27	1500894.JQNN01000001_gene529	1.05e-64	231.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,2VZ36@28216|Betaproteobacteria,472UX@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRD2_k127_3185289_23	450851.PHZ_c2869	2.717e-87	298.0	COG1266@1|root,COG1266@2|Bacteria,1NXKQ@1224|Proteobacteria	1224|Proteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRD2_k127_3185289_22	1123023.JIAI01000015_gene3217	4.036e-92	309.0	COG1794@1|root,COG1794@2|Bacteria,2H7J9@201174|Actinobacteria,4E0SW@85010|Pseudonocardiales	201174|Actinobacteria	M	Asp/Glu/Hydantoin racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
SRD2_k127_3185289_0	1123267.JONN01000001_gene1974	0.0	1264.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2TQSP@28211|Alphaproteobacteria,2K0F9@204457|Sphingomonadales	204457|Sphingomonadales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRD2_k127_3185289_36	1121123.AUAO01000005_gene1709	5.507e-35	139.0	2C7KN@1|root,336M6@2|Bacteria,1N4WC@1224|Proteobacteria,2UF7X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_3185289_7	460265.Mnod_3507	5.991e-208	664.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,1JST2@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1,PAS_9,Response_reg
SRD2_k127_3185289_10	1123257.AUFV01000007_gene336	6.02e-147	477.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,1RNIW@1236|Gammaproteobacteria,1X824@135614|Xanthomonadales	135614|Xanthomonadales	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRD2_k127_3185289_28	1071679.BG57_17550	1.917e-49	183.0	COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,2VQBM@28216|Betaproteobacteria,1K0DT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRD2_k127_3185289_30	452662.SJA_C1-25360	1.505e-47	187.0	COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,2U7RR@28211|Alphaproteobacteria,2K51K@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRD2_k127_3185289_21	1123267.JONN01000001_gene1765	4.327e-94	311.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2TRRE@28211|Alphaproteobacteria,2K0IZ@204457|Sphingomonadales	204457|Sphingomonadales	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
SRD2_k127_3185289_11	1120705.FG95_03100	1.203e-142	460.0	COG0665@1|root,COG0665@2|Bacteria,1Q9VR@1224|Proteobacteria,2U05R@28211|Alphaproteobacteria,2K32V@204457|Sphingomonadales	204457|Sphingomonadales	E	D-amino acid	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRD2_k127_3185289_5	1123267.JONN01000001_gene1766	6.013e-221	698.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2TRXC@28211|Alphaproteobacteria,2K0UP@204457|Sphingomonadales	204457|Sphingomonadales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
SRD2_k127_3185289_26	1123267.JONN01000001_gene1768	4.464e-72	251.0	2BXI0@1|root,2Z9A2@2|Bacteria,1MZF7@1224|Proteobacteria,2UCIX@28211|Alphaproteobacteria,2K3UM@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2459)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2459
SRD2_k127_3185289_37	1123267.JONN01000001_gene1769	1.785e-33	133.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria,2K62B@204457|Sphingomonadales	204457|Sphingomonadales	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRD2_k127_3185289_4	1123267.JONN01000001_gene1770	5.461e-229	720.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2TQYG@28211|Alphaproteobacteria,2K1DA@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRD2_k127_3185289_12	1123267.JONN01000001_gene1771	1.471e-130	423.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2TSFW@28211|Alphaproteobacteria,2K18K@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRD2_k127_3185289_20	1123267.JONN01000001_gene1772	1.007e-106	354.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2TRZ5@28211|Alphaproteobacteria,2JZVK@204457|Sphingomonadales	204457|Sphingomonadales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
SRD2_k127_3185289_8	1123267.JONN01000001_gene1773	2.026e-195	623.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2TREW@28211|Alphaproteobacteria,2K043@204457|Sphingomonadales	204457|Sphingomonadales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRD2_k127_3185289_32	318586.Pden_1076	1.209e-40	160.0	COG3797@1|root,COG3797@2|Bacteria,1PUJU@1224|Proteobacteria,2V1G4@28211|Alphaproteobacteria,2PY8P@265|Paracoccus	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRD2_k127_3185289_24	1123267.JONN01000001_gene1774	1.682e-82	285.0	COG0412@1|root,COG0412@2|Bacteria,1RJ0Q@1224|Proteobacteria,2UBJ9@28211|Alphaproteobacteria,2KDGK@204457|Sphingomonadales	204457|Sphingomonadales	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRD2_k127_3185289_2	1123267.JONN01000001_gene1776	0.0	1037.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2TRHK@28211|Alphaproteobacteria,2K00E@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
SRD2_k127_3185289_6	392499.Swit_3119	2.562e-219	694.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,2TS7R@28211|Alphaproteobacteria,2K0U5@204457|Sphingomonadales	204457|Sphingomonadales	E	peptidase S10 serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
SRD2_k127_3185289_15	1123267.JONN01000001_gene1778	8.073e-114	375.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2TTP3@28211|Alphaproteobacteria,2K0Q7@204457|Sphingomonadales	204457|Sphingomonadales	J	ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRD2_k127_3185289_18	1123267.JONN01000001_gene1779	3.394e-109	362.0	COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,2TRXW@28211|Alphaproteobacteria,2K1DS@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRD2_k127_3185289_35	491916.RHECIAT_PC0000643	2.938e-35	143.0	COG1028@1|root,COG1028@2|Bacteria,1R8HN@1224|Proteobacteria,2U9XQ@28211|Alphaproteobacteria,4B6ZH@82115|Rhizobiaceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRD2_k127_3185289_14	1123267.JONN01000001_gene1781	1.034e-115	387.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2K1AE@204457|Sphingomonadales	204457|Sphingomonadales	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
SRD2_k127_3185289_31	392499.Swit_1312	3.83e-46	174.0	COG2009@1|root,COG2009@2|Bacteria,1N02N@1224|Proteobacteria,2UC47@28211|Alphaproteobacteria,2K6ED@204457|Sphingomonadales	204457|Sphingomonadales	C	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRD2_k127_3185289_34	1123267.JONN01000001_gene1783	1.896e-38	149.0	COG2142@1|root,COG2142@2|Bacteria	2|Bacteria	C	succinate dehydrogenase activity	sdhD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRD2_k127_3185289_1	1123267.JONN01000001_gene1784	0.0	1084.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2TQJA@28211|Alphaproteobacteria,2K1NE@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRD2_k127_3185289_42	194867.ALBQ01000003_gene1135	5.51e-05	49.0	COG2184@1|root,COG2184@2|Bacteria,1RAVF@1224|Proteobacteria,2U59F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	Mobile mystery protein B	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRD2_k127_3185289_33	396588.Tgr7_3298	1.218e-38	149.0	COG3655@1|root,COG3655@2|Bacteria,1QZZC@1224|Proteobacteria,1T4CQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRD2_k127_3185289_25	1123255.JHYS01000028_gene173	3.034e-75	260.0	28JTN@1|root,2Z9IV@2|Bacteria,1RCK3@1224|Proteobacteria,2VRPV@28216|Betaproteobacteria,4AE4F@80864|Comamonadaceae	28216|Betaproteobacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_3185289_19	1082933.MEA186_29792	3.943e-108	360.0	COG1846@1|root,COG1846@2|Bacteria,1RETW@1224|Proteobacteria,2UQEX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_3185289_40	161528.ED21_31994	3.163e-10	63.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2K2HE@204457|Sphingomonadales	204457|Sphingomonadales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRD2_k127_3185289_16	1123267.JONN01000001_gene1758	1.403e-112	372.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2TQMD@28211|Alphaproteobacteria,2K19R@204457|Sphingomonadales	204457|Sphingomonadales	GM	Dehydrogenase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind
SRD2_k127_3185289_17	1081640.AGFU01000006_gene1203	4.519e-111	364.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2TSUR@28211|Alphaproteobacteria,2K0R1@204457|Sphingomonadales	204457|Sphingomonadales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRD2_k127_3185289_13	1123267.JONN01000001_gene1824	8.325e-125	401.0	COG0625@1|root,COG0625@2|Bacteria,1MXM4@1224|Proteobacteria,2TTXD@28211|Alphaproteobacteria,2K1DG@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
SRD2_k127_3185289_9	1123267.JONN01000001_gene2077	2.232e-173	549.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2TTQ2@28211|Alphaproteobacteria,2K10A@204457|Sphingomonadales	28211|Alphaproteobacteria	D	rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRD2_k127_3361274_2	629773.AORY01000021_gene2347	9.019e-59	205.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2K395@204457|Sphingomonadales	204457|Sphingomonadales	E	Glutamine amidotransferase domain	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRD2_k127_3361274_0	1123267.JONN01000001_gene970	7.021e-153	496.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2U148@28211|Alphaproteobacteria,2KD5X@204457|Sphingomonadales	204457|Sphingomonadales	M	Bacterial sugar transferase	-	-	2.7.8.40	ko:K21303	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Bac_transf
SRD2_k127_3361274_1	666509.RCA23_c07200	1.607e-97	330.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,2TU8I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glycos_transf_1
SRD2_k127_3392309_10	392499.Swit_0536	3.069e-41	167.0	COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,2TRWS@28211|Alphaproteobacteria,2K02K@204457|Sphingomonadales	204457|Sphingomonadales	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRD2_k127_3392309_6	69395.JQLZ01000003_gene449	9.01e-74	265.0	COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,2TRWS@28211|Alphaproteobacteria,2KGRN@204458|Caulobacterales	204458|Caulobacterales	E	amino acid	-	-	-	ko:K03294,ko:K03759	-	-	-	-	ko00000,ko02000	2.A.3.2	-	-	AA_permease_2
SRD2_k127_3392309_0	1123267.JONN01000002_gene198	2.117e-203	640.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,2K2R1@204457|Sphingomonadales	204457|Sphingomonadales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
SRD2_k127_3392309_11	1007104.SUS17_3133	6.101e-40	155.0	2DWID@1|root,340GN@2|Bacteria,1ND9Q@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_3392309_9	1123267.JONN01000001_gene620	4.839e-53	190.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2U767@28211|Alphaproteobacteria,2K4F9@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRD2_k127_3392309_12	1123267.JONN01000001_gene619	1.912e-37	141.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2UC13@28211|Alphaproteobacteria,2K5WV@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRD2_k127_3392309_3	1123267.JONN01000001_gene618	7.483e-93	308.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2TSC9@28211|Alphaproteobacteria,2K0UT@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRD2_k127_3392309_7	317655.Sala_2088	2.335e-72	251.0	COG0625@1|root,COG0625@2|Bacteria,1RJVR@1224|Proteobacteria,2U5SU@28211|Alphaproteobacteria,2K42G@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N_3
SRD2_k127_3392309_5	685778.AORL01000016_gene2326	1.893e-74	254.0	COG1396@1|root,COG1396@2|Bacteria,1RKW7@1224|Proteobacteria,2U9PU@28211|Alphaproteobacteria,2K2H6@204457|Sphingomonadales	204457|Sphingomonadales	K	XRE family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRD2_k127_3392309_4	1123267.JONN01000001_gene612	4.836e-84	291.0	COG1218@1|root,COG1218@2|Bacteria,1QY18@1224|Proteobacteria,2TXFA@28211|Alphaproteobacteria,2KEHZ@204457|Sphingomonadales	204457|Sphingomonadales	P	PFAM inositol monophosphatase	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
SRD2_k127_3392309_2	1123267.JONN01000001_gene611	6.574e-126	409.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,2TRPN@28211|Alphaproteobacteria,2K13W@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRD2_k127_3392309_1	1219035.NT2_07_00590	4.998e-132	434.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,2K0KA@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
SRD2_k127_3392309_8	392499.Swit_0853	1.72e-60	219.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,2U17R@28211|Alphaproteobacteria,2K18P@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,OMP_b-brl,OmpA
SRD2_k127_3435428_0	46429.BV95_00701	1.001e-249	779.0	COG0028@1|root,COG0028@2|Bacteria,1MWKP@1224|Proteobacteria,2TQK6@28211|Alphaproteobacteria,2K1ZC@204457|Sphingomonadales	204457|Sphingomonadales	EH	Belongs to the TPP enzyme family	-	-	1.2.5.1	ko:K00156	ko00620,map00620	-	R03145	RC00860	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRD2_k127_3435428_1	864069.MicloDRAFT_00034130	1.435e-209	684.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,1JQYU@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRD2_k127_3550925_10	745310.G432_09235	2.108e-29	117.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,2K17X@204457|Sphingomonadales	204457|Sphingomonadales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRD2_k127_3550925_3	323097.Nham_4495	6.174e-117	384.0	COG1223@1|root,COG1223@2|Bacteria,1QW7U@1224|Proteobacteria,2TWRV@28211|Alphaproteobacteria,3JURZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRD2_k127_3550925_0	1123267.JONN01000001_gene2357	1.355e-283	896.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2K01C@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
SRD2_k127_3550925_1	78245.Xaut_0974	1.875e-132	428.0	COG1409@1|root,COG1409@2|Bacteria,1MUQJ@1224|Proteobacteria,2TTSK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRD2_k127_3550925_11	395965.Msil_0391	3.666e-27	122.0	COG3794@1|root,COG3794@2|Bacteria,1RI9G@1224|Proteobacteria,2U7KA@28211|Alphaproteobacteria,3NBM7@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRD2_k127_3550925_8	78245.Xaut_0976	5.656e-46	173.0	COG1595@1|root,COG1595@2|Bacteria,1NRNT@1224|Proteobacteria,2TT5K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	'TIGRFAM RNA polymerase sigma factor, sigma-70 family'	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD2_k127_3550925_7	426117.M446_4787	2.326e-59	214.0	COG5662@1|root,COG5662@2|Bacteria,1MV95@1224|Proteobacteria,2TVRG@28211|Alphaproteobacteria,1JU5T@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRD2_k127_3550925_2	1090320.KB900607_gene8	5.933e-126	410.0	COG4705@1|root,COG4705@2|Bacteria,1MVMJ@1224|Proteobacteria,2TS5R@28211|Alphaproteobacteria,2K0R0@204457|Sphingomonadales	204457|Sphingomonadales	S	Repeat of Unknown Function (DUF347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF347
SRD2_k127_3550925_9	1219035.NT2_10_01140	3.038e-45	177.0	2905E@1|root,2ZMVA@2|Bacteria,1REVI@1224|Proteobacteria,2UAXB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
SRD2_k127_3550925_6	158500.BV97_04143	4.786e-73	261.0	COG3391@1|root,COG3391@2|Bacteria,1RFSR@1224|Proteobacteria,2U8VQ@28211|Alphaproteobacteria,2K235@204457|Sphingomonadales	204457|Sphingomonadales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_3550925_5	1096930.L284_01410	5.383e-84	285.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2TV3A@28211|Alphaproteobacteria,2K0MT@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD2_k127_3550925_4	1219049.SP5_083_00020	1.9e-95	321.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,2K1GW@204457|Sphingomonadales	204457|Sphingomonadales	T	Osmosensitive K channel	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
SRD2_k127_3561678_5	1123267.JONN01000001_gene1339	7.543e-213	663.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2TQZ0@28211|Alphaproteobacteria,2K0QX@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRD2_k127_3561678_12	1346791.M529_00565	5.227e-113	368.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2TSEJ@28211|Alphaproteobacteria,2K18U@204457|Sphingomonadales	204457|Sphingomonadales	C	NADH dehydrogenase	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRD2_k127_3561678_2	1123267.JONN01000001_gene1336	8.069e-254	789.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2TRAH@28211|Alphaproteobacteria,2JZYB@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRD2_k127_3561678_0	1123267.JONN01000001_gene1333	0.0	1084.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2TS97@28211|Alphaproteobacteria,2K16X@204457|Sphingomonadales	204457|Sphingomonadales	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3,NADH_dhqG_C
SRD2_k127_3561678_8	392499.Swit_2992	6.413e-186	587.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2TS09@28211|Alphaproteobacteria,2JZYY@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRD2_k127_3561678_13	627192.SLG_23100	1.851e-96	317.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2TRFE@28211|Alphaproteobacteria,2K01J@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRD2_k127_3561678_15	1123267.JONN01000001_gene1330	6.812e-80	272.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2TRB2@28211|Alphaproteobacteria,2JZZS@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRD2_k127_3561678_17	1123267.JONN01000001_gene1329	1.091e-40	153.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2U93P@28211|Alphaproteobacteria,2K53D@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRD2_k127_3561678_1	1123267.JONN01000001_gene1328	0.0	1028.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TQSS@28211|Alphaproteobacteria,2K1DM@204457|Sphingomonadales	204457|Sphingomonadales	CP	NADH ubiquinone oxidoreductase subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADH5_C,Proton_antipo_M,Proton_antipo_N
SRD2_k127_3561678_4	1030157.AFMP01000052_gene164	5.605e-237	744.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria,2K0EQ@204457|Sphingomonadales	204457|Sphingomonadales	C	NADH ubiquinone oxidoreductase subunit	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRD2_k127_3561678_7	1123267.JONN01000001_gene1326	3.966e-189	626.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2TQMX@28211|Alphaproteobacteria,2K08E@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRD2_k127_3561678_16	1044.EH31_02285	1.024e-55	213.0	COG0340@1|root,COG0340@2|Bacteria,1MWCC@1224|Proteobacteria,2TS82@28211|Alphaproteobacteria,2JZZZ@204457|Sphingomonadales	204457|Sphingomonadales	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,BPL_LplA_LipB_2
SRD2_k127_3561678_10	1123267.JONN01000001_gene1324	5.396e-122	396.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2TS5A@28211|Alphaproteobacteria,2K0SW@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRD2_k127_3561678_3	1123267.JONN01000001_gene1323	2.409e-242	760.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,2TQTR@28211|Alphaproteobacteria,2K04C@204457|Sphingomonadales	204457|Sphingomonadales	S	metallo-beta-lactamase	-	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
SRD2_k127_3561678_18	1123267.JONN01000001_gene1322	4.197e-28	117.0	COG5454@1|root,COG5454@2|Bacteria,1N8U9@1224|Proteobacteria,2UGCD@28211|Alphaproteobacteria,2K711@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1467
SRD2_k127_3561678_6	1123267.JONN01000001_gene1321	5.421e-207	668.0	COG1511@1|root,COG1511@2|Bacteria,1QVM2@1224|Proteobacteria,2TWI1@28211|Alphaproteobacteria,2KEGK@204457|Sphingomonadales	204457|Sphingomonadales	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_3561678_11	1123267.JONN01000001_gene1320	1.182e-116	388.0	2AKKZ@1|root,31BDD@2|Bacteria,1NNE3@1224|Proteobacteria,2UMPR@28211|Alphaproteobacteria,2K4ZT@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_3561678_14	1123267.JONN01000001_gene1318	1.553e-92	325.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2U3HG@28211|Alphaproteobacteria,2K0AE@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRD2_k127_3561678_9	1123267.JONN01000001_gene1317	4.117e-183	574.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,2K0JS@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRD2_k127_3563420_2	1123267.JONN01000001_gene1938	2.131e-125	407.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2TSMS@28211|Alphaproteobacteria,2K0NQ@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRD2_k127_3563420_1	1123267.JONN01000001_gene1937	1.201e-126	409.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2TRCF@28211|Alphaproteobacteria,2K0A2@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Acetoacetyl-CoA reductase	phbB	-	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
SRD2_k127_3563420_4	1408418.JNJH01000004_gene1988	2.063e-06	53.0	COG4321@1|root,COG4321@2|Bacteria,1N7Z2@1224|Proteobacteria,2UF7W@28211|Alphaproteobacteria,2JUIJ@204441|Rhodospirillales	204441|Rhodospirillales	S	Ribbon-helix-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	RHH_4
SRD2_k127_3563420_3	1123267.JONN01000001_gene1935	9.528e-94	315.0	COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,2U88X@28211|Alphaproteobacteria,2K3W3@204457|Sphingomonadales	204457|Sphingomonadales	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP
SRD2_k127_3563420_0	1112214.AHIS01000049_gene2357	0.0	1135.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,2K0WP@204457|Sphingomonadales	204457|Sphingomonadales	E	glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRD2_k127_3607089_12	685778.AORL01000004_gene3577	7.713e-97	332.0	COG2244@1|root,COG2244@2|Bacteria,1RDQG@1224|Proteobacteria,2U27A@28211|Alphaproteobacteria,2K2K5@204457|Sphingomonadales	204457|Sphingomonadales	S	PFAM polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
SRD2_k127_3607089_10	279714.FuraDRAFT_1133	3.528e-131	423.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2VIQF@28216|Betaproteobacteria,2KQJP@206351|Neisseriales	206351|Neisseriales	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
SRD2_k127_3607089_15	1123267.JONN01000002_gene240	1.678e-72	258.0	COG0647@1|root,COG0647@2|Bacteria,1MU9Y@1224|Proteobacteria,2TUH0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	sugar phosphatases of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
SRD2_k127_3607089_14	1096930.L284_05800	3.105e-79	275.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2TUQM@28211|Alphaproteobacteria,2K293@204457|Sphingomonadales	204457|Sphingomonadales	M	3-deoxy-manno-octulosonate cytidylyltransferase	-	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
SRD2_k127_3607089_13	1122180.Lokhon_00786	1.855e-93	316.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2TU5X@28211|Alphaproteobacteria,2P7TE@245186|Loktanella	28211|Alphaproteobacteria	M	SIS domain	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
SRD2_k127_3607089_5	1123269.NX02_14195	1.751e-194	615.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2TUFB@28211|Alphaproteobacteria,2K0FM@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
SRD2_k127_3607089_7	1123269.NX02_14190	5.352e-156	502.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2TRQ5@28211|Alphaproteobacteria,2K0GN@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the peptidase M24B family	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRD2_k127_3607089_9	1123267.JONN01000002_gene239	8.544e-145	475.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRJ1@28211|Alphaproteobacteria,2K0JH@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
SRD2_k127_3607089_3	745310.G432_18050	8.105e-198	620.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,2K1TR@204457|Sphingomonadales	204457|Sphingomonadales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRD2_k127_3607089_6	685778.AORL01000001_gene135	1.236e-173	554.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2U0BD@28211|Alphaproteobacteria,2KCU9@204457|Sphingomonadales	204457|Sphingomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRD2_k127_3607089_11	1123267.JONN01000002_gene353	1.132e-113	370.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2TR5M@28211|Alphaproteobacteria,2JZX6@204457|Sphingomonadales	204457|Sphingomonadales	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRD2_k127_3607089_0	1502850.FG91_03844	0.0	1239.0	COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria,2TW6Q@28211|Alphaproteobacteria,2K1IJ@204457|Sphingomonadales	204457|Sphingomonadales	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRD2_k127_3607089_8	1123267.JONN01000002_gene349	1.615e-151	484.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,2U0P8@28211|Alphaproteobacteria,2K007@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD2_k127_3607089_16	1380394.JADL01000001_gene2668	5.656e-69	250.0	COG0662@1|root,COG0662@2|Bacteria,1NX8W@1224|Proteobacteria,2TY4P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD2_k127_3607089_4	1123267.JONN01000002_gene348	2.296e-196	627.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2TS8W@28211|Alphaproteobacteria,2K02U@204457|Sphingomonadales	204457|Sphingomonadales	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRD2_k127_3607089_20	1120963.KB894491_gene1107	5.036e-06	56.0	2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_3607089_18	1449076.JOOE01000002_gene1394	2.717e-38	156.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,2U4ZG@28211|Alphaproteobacteria,2K230@204457|Sphingomonadales	204457|Sphingomonadales	S	Alkaline phosphatase with broad substrate specificity	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Phosphodiest
SRD2_k127_3607089_1	1123267.JONN01000002_gene126	5.812e-262	813.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2TRHX@28211|Alphaproteobacteria,2K04H@204457|Sphingomonadales	204457|Sphingomonadales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRD2_k127_3607089_2	1219049.SP5_073_00730	8.847e-237	741.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TRFY@28211|Alphaproteobacteria,2K0UD@204457|Sphingomonadales	204457|Sphingomonadales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRD2_k127_3607089_17	1123267.JONN01000002_gene124	8.333e-41	153.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2UBSZ@28211|Alphaproteobacteria,2K5XM@204457|Sphingomonadales	204457|Sphingomonadales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRD2_k127_3607089_19	1123267.JONN01000002_gene121	7.28e-12	66.0	COG2267@1|root,COG2267@2|Bacteria,1MVDA@1224|Proteobacteria,2TUDQ@28211|Alphaproteobacteria,2K1MR@204457|Sphingomonadales	204457|Sphingomonadales	I	Protein of unknown function (DUF3089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3089
SRD2_k127_3748370_2	450851.PHZ_c1673	3.929e-79	275.0	2CCCK@1|root,2Z7UH@2|Bacteria,1R3SV@1224|Proteobacteria,2UH90@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_3748370_1	1502850.FG91_00756	1.491e-114	381.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2TQU4@28211|Alphaproteobacteria,2KCTI@204457|Sphingomonadales	204457|Sphingomonadales	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRD2_k127_3748370_3	1007104.SUS17_3578	2.045e-55	201.0	COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,2U96D@28211|Alphaproteobacteria,2K489@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K04080	-	-	-	-	ko00000,ko03110	-	-	-	HSP20
SRD2_k127_3748370_0	1123267.JONN01000001_gene527	7.312e-304	939.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2TQZV@28211|Alphaproteobacteria,2K2GE@204457|Sphingomonadales	204457|Sphingomonadales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRD2_k127_382664_2	1331060.RLDS_23440	6.844e-87	290.0	COG1708@1|root,COG2250@1|root,COG1708@2|Bacteria,COG2250@2|Bacteria,1PWC5@1224|Proteobacteria,2TT5M@28211|Alphaproteobacteria,2K1BT@204457|Sphingomonadales	204457|Sphingomonadales	S	Nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
SRD2_k127_382664_1	1112214.AHIS01000089_gene921	2.83e-125	414.0	COG3555@1|root,COG3555@2|Bacteria,1MXZE@1224|Proteobacteria,2U0S2@28211|Alphaproteobacteria,2K0VK@204457|Sphingomonadales	204457|Sphingomonadales	O	Aspartyl/Asparaginyl beta-hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Arg_Hydrox
SRD2_k127_382664_5	1219049.SP5_090_00140	5.213e-19	87.0	2FC5G@1|root,3449A@2|Bacteria,1NB1K@1224|Proteobacteria,2UFY7@28211|Alphaproteobacteria,2K6YG@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_382664_4	1470591.BW41_02401	4.044e-28	115.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,2K5Z5@204457|Sphingomonadales	204457|Sphingomonadales	K	Cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRD2_k127_382664_6	1379701.JPJC01000095_gene2323	8.603e-07	53.0	2AMEG@1|root,31C9X@2|Bacteria,1Q8AQ@1224|Proteobacteria,2VEGR@28211|Alphaproteobacteria,2K7UN@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_382664_3	348824.LPU83_1253	2.639e-67	236.0	COG3791@1|root,COG3791@2|Bacteria,1RH2A@1224|Proteobacteria,2U731@28211|Alphaproteobacteria,4BE1G@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRD2_k127_382664_0	1449076.JOOE01000002_gene990	0.0	1062.0	COG0840@1|root,COG1511@1|root,COG3437@1|root,COG5002@1|root,COG0840@2|Bacteria,COG1511@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TWEB@28211|Alphaproteobacteria,2KEIX@204457|Sphingomonadales	204457|Sphingomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,Response_reg
SRD2_k127_3867335_1	745310.G432_01420	1.605e-208	668.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1R81Z@1224|Proteobacteria,2U2DW@28211|Alphaproteobacteria,2K1YH@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRD2_k127_3867335_0	1123267.JONN01000001_gene1238	0.0	1255.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,MRJP
SRD2_k127_3867335_3	1123267.JONN01000001_gene1239	2.448e-97	329.0	2C1YS@1|root,2ZD2Y@2|Bacteria	2|Bacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SRD2_k127_3867335_5	1123267.JONN01000001_gene951	5.003e-44	161.0	2C82G@1|root,32RK9@2|Bacteria,1MZV5@1224|Proteobacteria,2UCEY@28211|Alphaproteobacteria,2K7ZX@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRD2_k127_3867335_2	1057002.KB905370_gene2611	7.434e-112	382.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_8
SRD2_k127_3876158_6	653733.Selin_2485	6.631e-11	72.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,Trans_reg_C,dCache_1
SRD2_k127_3876158_7	1090319.KE386571_gene318	3.143e-09	67.0	COG1846@1|root,COG2202@1|root,COG1846@2|Bacteria,COG2202@2|Bacteria,1N0NQ@1224|Proteobacteria,2UEIA@28211|Alphaproteobacteria,2K80Y@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,PAS_3
SRD2_k127_3876158_4	1123267.JONN01000001_gene614	4.095e-37	146.0	COG1846@1|root,COG1846@2|Bacteria,1N2Q4@1224|Proteobacteria,2UC5A@28211|Alphaproteobacteria,2K54U@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR
SRD2_k127_3876158_2	161528.ED21_23488	3.102e-104	366.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TS9V@28211|Alphaproteobacteria,2K1VI@204457|Sphingomonadales	204457|Sphingomonadales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRD2_k127_3876158_1	685778.AORL01000010_gene3052	5.168e-125	409.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria,2K19V@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the GST superfamily	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_N,GST_N_3
SRD2_k127_3876158_0	113395.AXAI01000049_gene3604	5.414e-156	498.0	28PP7@1|root,2ZCBP@2|Bacteria,1R53H@1224|Proteobacteria,2VGU9@28211|Alphaproteobacteria,3JUCR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_3876158_3	323097.Nham_3631	1.54e-47	176.0	COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,2UCUJ@28211|Alphaproteobacteria,3JZ8G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRD2_k127_3876158_5	1207058.L53_10475	8.59e-14	74.0	COG2823@1|root,COG2823@2|Bacteria,1RDBG@1224|Proteobacteria,2U89Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4001179_1	864069.MicloDRAFT_00026070	1.566e-166	543.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,2TSN2@28211|Alphaproteobacteria,1JSAQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	NT	Signal transducing histidine kinase, homodimeric	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SRD2_k127_4001179_5	864069.MicloDRAFT_00026080	2.55e-09	61.0	2EHSS@1|root,33BIG@2|Bacteria,1NI0S@1224|Proteobacteria,2UJTI@28211|Alphaproteobacteria,1JWS0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4001179_4	627192.SLG_13920	5.628e-50	180.0	COG2197@1|root,COG2197@2|Bacteria,1N7EG@1224|Proteobacteria,2UASY@28211|Alphaproteobacteria,2K5U3@204457|Sphingomonadales	204457|Sphingomonadales	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRD2_k127_4001179_2	1335760.ASTG01000003_gene1534	2.369e-81	278.0	COG1776@1|root,COG1776@2|Bacteria,1R430@1224|Proteobacteria,2U4PV@28211|Alphaproteobacteria,2K8YT@204457|Sphingomonadales	204457|Sphingomonadales	NT	chemotaxis protein	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC,CheX
SRD2_k127_4001179_0	555793.WSK_0222	1.138e-221	706.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2K01C@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,ParD_antitoxin,Response_reg
SRD2_k127_4001179_3	13690.CP98_00552	1.194e-72	248.0	COG1708@1|root,COG2250@1|root,COG1708@2|Bacteria,COG2250@2|Bacteria,1PWC5@1224|Proteobacteria,2TT5M@28211|Alphaproteobacteria,2K1BT@204457|Sphingomonadales	204457|Sphingomonadales	S	Nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HEPN,NTP_transf_2
SRD2_k127_4049031_3	1123267.JONN01000001_gene1168	8.686e-22	96.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TTGJ@28211|Alphaproteobacteria,2K0KM@204457|Sphingomonadales	204457|Sphingomonadales	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRD2_k127_4049031_0	1038860.AXAP01000010_gene7778	4.444e-202	639.0	COG1012@1|root,COG1012@2|Bacteria,1MW72@1224|Proteobacteria,2TUN4@28211|Alphaproteobacteria,3JUAW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	alh	GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD2_k127_4049031_1	1123267.JONN01000001_gene1169	9.302e-113	370.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TW2U@28211|Alphaproteobacteria,2KE9I@204457|Sphingomonadales	204457|Sphingomonadales	T	CHASE2	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,EAL
SRD2_k127_4049031_2	1123267.JONN01000001_gene1170	3.342e-34	133.0	COG0745@1|root,COG0745@2|Bacteria	1123267.JONN01000001_gene1170|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4078647_5	1282360.ABAC460_10305	6.542e-65	228.0	COG0346@1|root,COG0346@2|Bacteria,1RHRF@1224|Proteobacteria	1224|Proteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD2_k127_4078647_6	1218075.BAYA01000053_gene6880	3.426e-33	134.0	COG4420@1|root,COG4420@2|Bacteria,1P3R0@1224|Proteobacteria,2W6Z4@28216|Betaproteobacteria,1KDBY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4078647_1	402777.KB235903_gene1433	1.215e-175	561.0	COG0161@1|root,COG0161@2|Bacteria,1G1QE@1117|Cyanobacteria,1H9SQ@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.18,2.6.1.62	ko:K00822,ko:K00833	ko00280,ko00410,ko00640,ko00780,ko01100,map00280,map00410,map00640,map00780,map01100	M00123,M00573,M00577	R00907,R03231,R04187	RC00006,RC00008,RC00062,RC00160,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD2_k127_4078647_3	1123267.JONN01000001_gene1818	2.771e-167	531.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2TQRT@28211|Alphaproteobacteria,2K0DQ@204457|Sphingomonadales	204457|Sphingomonadales	S	2-nitropropane dioxygenase	-	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO,ThiG
SRD2_k127_4078647_2	392499.Swit_4503	2.086e-169	543.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2TRFA@28211|Alphaproteobacteria,2K044@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRD2_k127_4078647_0	1346791.M529_19490	3.828e-177	565.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2TQPB@28211|Alphaproteobacteria,2JZWD@204457|Sphingomonadales	204457|Sphingomonadales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRD2_k127_4078647_4	1174684.EBMC1_00065	2.954e-81	279.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2TRIK@28211|Alphaproteobacteria,2K0DH@204457|Sphingomonadales	204457|Sphingomonadales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
SRD2_k127_4106940_2	1007104.SUS17_2150	2.512e-140	456.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2TRJS@28211|Alphaproteobacteria,2K05A@204457|Sphingomonadales	204457|Sphingomonadales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
SRD2_k127_4106940_3	1449076.JOOE01000003_gene3725	9.953e-135	441.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2TQZW@28211|Alphaproteobacteria,2K0HT@204457|Sphingomonadales	204457|Sphingomonadales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
SRD2_k127_4106940_5	1123267.JONN01000001_gene2153	8.252e-75	257.0	COG0861@1|root,COG0861@2|Bacteria,1PN8B@1224|Proteobacteria,2TUV5@28211|Alphaproteobacteria,2K1SQ@204457|Sphingomonadales	204457|Sphingomonadales	P	membrane protein, TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
SRD2_k127_4106940_0	1123267.JONN01000001_gene2154	4.932e-249	771.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,2K1UD@204457|Sphingomonadales	204457|Sphingomonadales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRD2_k127_4106940_6	1123267.JONN01000001_gene2155	1.734e-66	231.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2U987@28211|Alphaproteobacteria,2K4J9@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
SRD2_k127_4106940_1	1123269.NX02_25420	8.124e-152	486.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2TQQV@28211|Alphaproteobacteria,2JZZP@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRD2_k127_4106940_10	1123267.JONN01000001_gene2157	6.049e-62	219.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2U9H5@28211|Alphaproteobacteria,2K2S3@204457|Sphingomonadales	204457|Sphingomonadales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRD2_k127_4106940_8	1123267.JONN01000001_gene2159	1.526e-62	221.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2U765@28211|Alphaproteobacteria,2K3YB@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
SRD2_k127_4106940_4	685778.AORL01000022_gene1583	3.784e-99	331.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2TTFF@28211|Alphaproteobacteria,2K06H@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
SRD2_k127_4106940_9	1123267.JONN01000001_gene2161	5.165e-62	222.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2TV3J@28211|Alphaproteobacteria,2K2CA@204457|Sphingomonadales	204457|Sphingomonadales	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	-	-	-	-	-	-	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRD2_k127_4106940_11	1123267.JONN01000001_gene2162	1.616e-61	216.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2U7B0@28211|Alphaproteobacteria,2K6E5@204457|Sphingomonadales	204457|Sphingomonadales	G	PTS IIA-like nitrogen-regulatory protein PtsN	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
SRD2_k127_4106940_13	702113.PP1Y_AT37249	2.592e-21	100.0	COG5447@1|root,COG5447@2|Bacteria,1N1KU@1224|Proteobacteria,2UFES@28211|Alphaproteobacteria,2K70S@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1491)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1491
SRD2_k127_4106940_12	1123267.JONN01000001_gene2165	3.432e-52	192.0	COG3773@1|root,COG3773@2|Bacteria,1RDSV@1224|Proteobacteria,2U8XY@28211|Alphaproteobacteria,2K4PG@204457|Sphingomonadales	204457|Sphingomonadales	M	COG3773 Cell wall hydrolyses involved in spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
SRD2_k127_4106940_7	1123267.JONN01000001_gene2166	2.063e-66	229.0	COG5321@1|root,COG5321@2|Bacteria,1RDXW@1224|Proteobacteria,2U73Y@28211|Alphaproteobacteria,2K5GG@204457|Sphingomonadales	204457|Sphingomonadales	S	DNA repair protein MmcB-like	-	-	-	-	-	-	-	-	-	-	-	-	MmcB-like
SRD2_k127_4108582_2	1550073.JROH01000011_gene2092	2.448e-94	314.0	COG1506@1|root,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,2TRVE@28211|Alphaproteobacteria,2K0U1@204457|Sphingomonadales	204457|Sphingomonadales	E	peptidase S9	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
SRD2_k127_4108582_3	1449076.JOOE01000003_gene3197	8.807e-69	251.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2TRUD@28211|Alphaproteobacteria,2K414@204457|Sphingomonadales	204457|Sphingomonadales	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
SRD2_k127_4108582_1	1123267.JONN01000002_gene251	5.373e-128	436.0	COG2234@1|root,COG2234@2|Bacteria,1R56X@1224|Proteobacteria,2U2G7@28211|Alphaproteobacteria,2K2WC@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRD2_k127_4108582_0	46429.BV95_00751	7.656e-186	585.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria,2K104@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRD2_k127_4137991_2	1007104.SUS17_1738	2.055e-204	641.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria,2K0M5@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C,DUF779
SRD2_k127_4137991_6	1112214.AHIS01000025_gene1246	1.154e-24	112.0	2AKZG@1|root,31BT4@2|Bacteria,1Q7R6@1224|Proteobacteria,2VDWQ@28211|Alphaproteobacteria,2K6B3@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3833)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3833
SRD2_k127_4137991_0	745310.G432_00370	4.823e-219	694.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TRAP@28211|Alphaproteobacteria,2K0IY@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRD2_k127_4137991_3	1123267.JONN01000001_gene2467	1.043e-107	353.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,2U5C7@28211|Alphaproteobacteria,2JZZT@204457|Sphingomonadales	204457|Sphingomonadales	G	6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRD2_k127_4137991_4	1123267.JONN01000001_gene521	2.875e-45	173.0	COG0810@1|root,COG0810@2|Bacteria,1NB5F@1224|Proteobacteria,2UJ8K@28211|Alphaproteobacteria,2KDGQ@204457|Sphingomonadales	204457|Sphingomonadales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRD2_k127_4137991_7	883126.HMPREF9710_02033	1.395e-06	51.0	COG3729@1|root,COG3729@2|Bacteria,1NH1J@1224|Proteobacteria,2VY5U@28216|Betaproteobacteria,477VZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Stress-induced bacterial acidophilic repeat motif	-	-	-	-	-	-	-	-	-	-	-	-	KGG
SRD2_k127_4137991_5	1463854.JOHT01000063_gene3448	8.117e-26	114.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,SnoaL_3
SRD2_k127_4137991_1	1123267.JONN01000001_gene1482	7.417e-216	689.0	COG4206@1|root,COG4206@2|Bacteria,1R1WX@1224|Proteobacteria,2U0GK@28211|Alphaproteobacteria,2K1DC@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRD2_k127_4167921_24	1123267.JONN01000001_gene1042	7.206e-75	254.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,2K0VS@204457|Sphingomonadales	204457|Sphingomonadales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRD2_k127_4167921_21	1123267.JONN01000002_gene255	2.259e-80	276.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,2TT08@28211|Alphaproteobacteria,2K7DA@204457|Sphingomonadales	204457|Sphingomonadales	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
SRD2_k127_4167921_14	685778.AORL01000021_gene765	5.737e-110	364.0	COG0657@1|root,COG0657@2|Bacteria,1N5QB@1224|Proteobacteria,2U1WU@28211|Alphaproteobacteria,2K1HS@204457|Sphingomonadales	204457|Sphingomonadales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
SRD2_k127_4167921_3	685778.AORL01000021_gene434	2.269e-195	620.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2U4WG@28211|Alphaproteobacteria,2K1X8@204457|Sphingomonadales	204457|Sphingomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRD2_k127_4167921_25	1346791.M529_04760	1.309e-73	251.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2U5B5@28211|Alphaproteobacteria,2K0C7@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRD2_k127_4167921_17	1123269.NX02_14070	5.268e-90	299.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2U5FM@28211|Alphaproteobacteria,2K28X@204457|Sphingomonadales	204457|Sphingomonadales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRD2_k127_4167921_45	1114964.L485_04695	1.646e-13	78.0	2AGMS@1|root,2ZXZW@2|Bacteria,1NIGW@1224|Proteobacteria,2UN9G@28211|Alphaproteobacteria,2KDQQ@204457|Sphingomonadales	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4167921_36	391616.OA238_c31440	1.36e-30	128.0	COG1051@1|root,COG1051@2|Bacteria,1QU3V@1224|Proteobacteria,2TVYC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRD2_k127_4167921_18	1041147.AUFB01000006_gene2359	5.707e-89	312.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1MY43@1224|Proteobacteria,2TQRV@28211|Alphaproteobacteria,4B8QY@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
SRD2_k127_4167921_48	693986.MOC_2653	0.000946	44.0	2AATE@1|root,31061@2|Bacteria,1PN64@1224|Proteobacteria,2V0SP@28211|Alphaproteobacteria,1JWA6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4167921_22	1081640.AGFU01000009_gene1414	9.786e-76	261.0	COG0664@1|root,COG0664@2|Bacteria,1RA0S@1224|Proteobacteria,2U65I@28211|Alphaproteobacteria,2KCW3@204457|Sphingomonadales	204457|Sphingomonadales	K	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
SRD2_k127_4167921_23	1114964.L485_09115	2.203e-75	267.0	COG0392@1|root,COG0392@2|Bacteria,1R468@1224|Proteobacteria,2U0QT@28211|Alphaproteobacteria,2K65B@204457|Sphingomonadales	204457|Sphingomonadales	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRD2_k127_4167921_38	745310.G432_13995	2.594e-25	108.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2UF5Y@28211|Alphaproteobacteria,2K75D@204457|Sphingomonadales	204457|Sphingomonadales	P	CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRD2_k127_4167921_8	1346791.M529_04745	3.524e-133	433.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,2K0QN@204457|Sphingomonadales	204457|Sphingomonadales	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRD2_k127_4167921_34	1219045.BV98_001969	2.659e-34	136.0	2EC1J@1|root,3360P@2|Bacteria,1NCAE@1224|Proteobacteria,2UMDW@28211|Alphaproteobacteria,2K72C@204457|Sphingomonadales	204457|Sphingomonadales	S	MerC mercury resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MerC
SRD2_k127_4167921_26	1123267.JONN01000002_gene262	1.192e-67	241.0	COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,2U9G4@28211|Alphaproteobacteria,2K4GM@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the Fur family	-	-	-	ko:K09823	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	FUR
SRD2_k127_4167921_0	1123267.JONN01000002_gene265	0.0	1010.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2TRDD@28211|Alphaproteobacteria,2K0XY@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRD2_k127_4167921_12	1449076.JOOE01000006_gene647	8.846e-116	377.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,2TRW9@28211|Alphaproteobacteria,2K0J2@204457|Sphingomonadales	204457|Sphingomonadales	J	Hemolysin	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRD2_k127_4167921_35	1081640.AGFU01000025_gene2487	1.047e-30	124.0	COG2960@1|root,COG2960@2|Bacteria,1N725@1224|Proteobacteria,2UFEP@28211|Alphaproteobacteria,2K74V@204457|Sphingomonadales	204457|Sphingomonadales	S	Membrane fusogenic activity	-	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
SRD2_k127_4167921_20	1123267.JONN01000002_gene270	2.705e-81	274.0	COG5465@1|root,COG5465@2|Bacteria,1REC1@1224|Proteobacteria,2U7UP@28211|Alphaproteobacteria,2K1T3@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
SRD2_k127_4167921_28	1123267.JONN01000002_gene271	2.624e-63	229.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2TTY7@28211|Alphaproteobacteria,2K353@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRD2_k127_4167921_7	1123267.JONN01000002_gene272	2.795e-147	470.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TR1H@28211|Alphaproteobacteria,2K0G3@204457|Sphingomonadales	204457|Sphingomonadales	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRD2_k127_4167921_27	1122604.JONR01000039_gene3785	4.481e-67	233.0	COG1695@1|root,COG1695@2|Bacteria,1NKS4@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRD2_k127_4167921_37	392499.Swit_4049	6.638e-27	114.0	28ZXZ@1|root,2ZMNF@2|Bacteria,1NM5Z@1224|Proteobacteria,2UWBC@28211|Alphaproteobacteria,2K81I@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4167921_33	1088721.NSU_1054	3.334e-38	149.0	COG3805@1|root,COG3805@2|Bacteria,1PK15@1224|Proteobacteria,2VBK3@28211|Alphaproteobacteria,2K89Y@204457|Sphingomonadales	204457|Sphingomonadales	Q	Dopa 4,5-dioxygenase family	-	-	-	ko:K10253	-	-	-	-	ko00000,ko01000	-	-	-	DOPA_dioxygen
SRD2_k127_4167921_40	652103.Rpdx1_3931	5.872e-24	106.0	2BH9F@1|root,32BAX@2|Bacteria,1NC2G@1224|Proteobacteria,2UH0Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4167921_30	411684.HPDFL43_00635	6.038e-47	175.0	COG3311@1|root,COG3311@2|Bacteria,1RI96@1224|Proteobacteria,2U90V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	dNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4167921_11	1057002.KB905370_gene2611	1.12e-120	409.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_8
SRD2_k127_4167921_42	1177179.A11A3_07198	1.573e-21	103.0	COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,1S2I3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRD2_k127_4167921_6	443598.AUFA01000014_gene7019	1.442e-150	483.0	COG0604@1|root,COG0604@2|Bacteria,1R8NX@1224|Proteobacteria,2TUG0@28211|Alphaproteobacteria,3JW8S@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRD2_k127_4167921_39	392499.Swit_1237	3.18e-25	109.0	COG1366@1|root,COG1366@2|Bacteria,1P4SA@1224|Proteobacteria,2UEM0@28211|Alphaproteobacteria,2K64R@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRD2_k127_4167921_13	392499.Swit_1236	1.988e-114	377.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,2U14Z@28211|Alphaproteobacteria,2K2H3@204457|Sphingomonadales	204457|Sphingomonadales	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRD2_k127_4167921_1	392499.Swit_1235	1.613e-226	721.0	COG2208@1|root,COG4252@1|root,COG2208@2|Bacteria,COG4252@2|Bacteria,1QUNZ@1224|Proteobacteria,2TW2I@28211|Alphaproteobacteria,2K2IY@204457|Sphingomonadales	204457|Sphingomonadales	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,SpoIIE
SRD2_k127_4167921_31	392499.Swit_1234	6.973e-47	177.0	COG2885@1|root,COG2885@2|Bacteria,1MZKA@1224|Proteobacteria,2UG8A@28211|Alphaproteobacteria,2K64M@204457|Sphingomonadales	204457|Sphingomonadales	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRD2_k127_4167921_29	392499.Swit_1233	1.224e-47	175.0	COG4254@1|root,COG4254@2|Bacteria,1N739@1224|Proteobacteria,2TY9V@28211|Alphaproteobacteria,2K5CY@204457|Sphingomonadales	204457|Sphingomonadales	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRD2_k127_4167921_41	392499.Swit_1232	2.062e-22	103.0	COG2172@1|root,COG2172@2|Bacteria,1NHFM@1224|Proteobacteria,2UN5Q@28211|Alphaproteobacteria,2K7AA@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
SRD2_k127_4167921_10	1292034.OR37_03541	3.204e-123	423.0	COG3664@1|root,COG3664@2|Bacteria,1NSK2@1224|Proteobacteria	1224|Proteobacteria	G	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
SRD2_k127_4167921_5	1122612.AUBA01000003_gene1612	4.139e-180	574.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2TR5F@28211|Alphaproteobacteria,2K04J@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRD2_k127_4167921_4	279238.Saro_1668	8.187e-190	601.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TRI3@28211|Alphaproteobacteria,2K00Q@204457|Sphingomonadales	204457|Sphingomonadales	C	belongs to the aldehyde dehydrogenase family	ligV	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRD2_k127_4167921_44	1219049.SP5_090_00090	9.94e-16	83.0	2BSQ9@1|root,32MT3@2|Bacteria,1NZFC@1224|Proteobacteria,2USS4@28211|Alphaproteobacteria,2K6MK@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
SRD2_k127_4167921_9	1123267.JONN01000001_gene1168	1.202e-132	442.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TTGJ@28211|Alphaproteobacteria,2K0KM@204457|Sphingomonadales	204457|Sphingomonadales	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRD2_k127_4167921_2	349102.Rsph17025_2725	7.015e-199	640.0	COG1012@1|root,COG1012@2|Bacteria,1MW72@1224|Proteobacteria,2TUN4@28211|Alphaproteobacteria,1FB6E@1060|Rhodobacter	28211|Alphaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	alh	GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD2_k127_4167921_15	1123267.JONN01000001_gene1169	1.339e-101	344.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TW2U@28211|Alphaproteobacteria,2KE9I@204457|Sphingomonadales	204457|Sphingomonadales	T	CHASE2	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,EAL
SRD2_k127_4167921_32	1123267.JONN01000001_gene1170	5.125e-41	154.0	COG0745@1|root,COG0745@2|Bacteria	1123267.JONN01000001_gene1170|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4167921_19	1123267.JONN01000001_gene1172	4.835e-88	294.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2TSAM@28211|Alphaproteobacteria,2K0CZ@204457|Sphingomonadales	204457|Sphingomonadales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRD2_k127_4167921_46	633131.TR2A62_2201	1.536e-07	53.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2TRIM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
SRD2_k127_4252993_23	1449076.JOOE01000004_gene70	3.855e-57	201.0	COG1793@1|root,COG1793@2|Bacteria,1R4SI@1224|Proteobacteria,2U213@28211|Alphaproteobacteria,2K3AE@204457|Sphingomonadales	204457|Sphingomonadales	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRD2_k127_4252993_14	1123267.JONN01000001_gene2285	3.255e-106	371.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2TQSZ@28211|Alphaproteobacteria,2K3CB@204457|Sphingomonadales	204457|Sphingomonadales	E	Arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRD2_k127_4252993_12	1502851.FG93_00408	2.57e-123	407.0	COG1228@1|root,COG1228@2|Bacteria,1MUYR@1224|Proteobacteria,2TSA1@28211|Alphaproteobacteria,3JVJX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	imidazolonepropionase activity	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRD2_k127_4252993_24	1192759.AKIB01000014_gene1648	1.605e-49	185.0	COG2141@1|root,COG2141@2|Bacteria,1RGXC@1224|Proteobacteria,2UGST@28211|Alphaproteobacteria,2K70E@204457|Sphingomonadales	204457|Sphingomonadales	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4252993_2	1123267.JONN01000001_gene2288	6.036e-318	977.0	COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,2TSJR@28211|Alphaproteobacteria,2K2BT@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRD2_k127_4252993_5	1123267.JONN01000001_gene2292	2.621e-222	703.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,2TSPJ@28211|Alphaproteobacteria,2K1IZ@204457|Sphingomonadales	204457|Sphingomonadales	E	Histidine	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRD2_k127_4252993_28	1123267.JONN01000001_gene2315	9.361e-18	87.0	COG4731@1|root,COG4731@2|Bacteria,1RHN9@1224|Proteobacteria,2UEIJ@28211|Alphaproteobacteria,2K69D@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
SRD2_k127_4252993_26	1449076.JOOE01000003_gene3330	1.254e-27	117.0	COG4731@1|root,COG4731@2|Bacteria,1RHN9@1224|Proteobacteria,2UEIJ@28211|Alphaproteobacteria,2K69D@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
SRD2_k127_4252993_0	1123267.JONN01000001_gene2314	0.0	1557.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2TRUB@28211|Alphaproteobacteria,2JZWI@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRD2_k127_4252993_9	1123267.JONN01000001_gene2313	5.959e-163	529.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2TQVR@28211|Alphaproteobacteria,2JZYV@204457|Sphingomonadales	204457|Sphingomonadales	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
SRD2_k127_4252993_25	1234595.C725_2398	1.252e-47	179.0	COG4544@1|root,COG4544@2|Bacteria,1MY56@1224|Proteobacteria,2TT91@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SOS response	-	-	-	ko:K14160	-	-	-	-	ko00000,ko03400	-	-	-	-
SRD2_k127_4252993_20	1123267.JONN01000001_gene2375	6.949e-66	237.0	COG1075@1|root,COG1075@2|Bacteria,1NJNA@1224|Proteobacteria,2TSQC@28211|Alphaproteobacteria,2K4XJ@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRD2_k127_4252993_6	1123267.JONN01000001_gene2376	1.486e-201	636.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2TR4T@28211|Alphaproteobacteria,2K0IX@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRD2_k127_4252993_21	1537715.JQFJ01000002_gene708	1.383e-63	224.0	COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,2UCHI@28211|Alphaproteobacteria,2K5IK@204457|Sphingomonadales	204457|Sphingomonadales	I	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Flavin_Reduct
SRD2_k127_4252993_1	685778.AORL01000021_gene958	0.0	1072.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2TTAX@28211|Alphaproteobacteria,2KDD3@204457|Sphingomonadales	204457|Sphingomonadales	E	COG1505 Serine proteases of the peptidase family S9A	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRD2_k127_4252993_17	1123267.JONN01000001_gene2373	6.436e-83	284.0	COG3186@1|root,COG3186@2|Bacteria,1MU29@1224|Proteobacteria,2TU1E@28211|Alphaproteobacteria,2K01F@204457|Sphingomonadales	204457|Sphingomonadales	E	Phenylalanine-4-hydroxylase	phhA	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
SRD2_k127_4252993_29	13690.CP98_01407	5.419e-07	54.0	COG3847@1|root,COG3847@2|Bacteria,1Q1G3@1224|Proteobacteria,2V11R@28211|Alphaproteobacteria,2K7TI@204457|Sphingomonadales	204457|Sphingomonadales	U	Flp pilus assembly protein, pilin Flp	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
SRD2_k127_4252993_3	1470591.BW41_01728	9.379e-265	830.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSUQ@28211|Alphaproteobacteria,2K0GU@204457|Sphingomonadales	204457|Sphingomonadales	O	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRD2_k127_4252993_27	1123267.JONN01000001_gene2371	9.198e-27	112.0	COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2UBWN@28211|Alphaproteobacteria,2K5VW@204457|Sphingomonadales	204457|Sphingomonadales	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRD2_k127_4252993_11	1380394.JADL01000012_gene1023	2.69e-156	501.0	COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,2TRCC@28211|Alphaproteobacteria,2JQJ4@204441|Rhodospirillales	204441|Rhodospirillales	E	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
SRD2_k127_4252993_8	1123267.JONN01000001_gene2369	3.633e-193	617.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2K04I@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
SRD2_k127_4252993_22	1090320.KB900605_gene3037	5.151e-61	215.0	COG2151@1|root,COG2151@2|Bacteria,1RF3S@1224|Proteobacteria,2TRQW@28211|Alphaproteobacteria,2K4PD@204457|Sphingomonadales	204457|Sphingomonadales	L	Iron-sulfur cluster assembly protein	-	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRD2_k127_4252993_7	1123267.JONN01000001_gene517	2.642e-197	620.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2TRS9@28211|Alphaproteobacteria,2KCTY@204457|Sphingomonadales	204457|Sphingomonadales	M	mandelate racemase muconate lactonizing	-	-	4.2.1.6,4.2.1.8,5.1.2.2	ko:K01684,ko:K01781,ko:K08323	ko00040,ko00052,ko00627,ko01100,ko01120,map00040,map00052,map00627,map01100,map01120	M00061,M00552	R03033,R03791,R04161,R05606	RC00543,RC00998	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRD2_k127_4252993_4	1123267.JONN01000001_gene516	4.7e-231	719.0	COG2723@1|root,COG2723@2|Bacteria,1MWU7@1224|Proteobacteria,2TT4I@28211|Alphaproteobacteria,2K354@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_1
SRD2_k127_4252993_15	1123267.JONN01000001_gene514	8.883e-89	301.0	COG3734@1|root,COG3734@2|Bacteria,1MWGX@1224|Proteobacteria,2TTG8@28211|Alphaproteobacteria,2K1K8@204457|Sphingomonadales	204457|Sphingomonadales	G	2-keto-3-deoxy-galactonokinase	dgoK	-	2.7.1.58	ko:K00883	ko00052,ko01100,map00052,map01100	M00552	R03387	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	DGOK
SRD2_k127_4252993_19	1123267.JONN01000001_gene513	2.234e-74	259.0	COG0800@1|root,COG0800@2|Bacteria,1RD0T@1224|Proteobacteria,2U7AQ@28211|Alphaproteobacteria,2K1WJ@204457|Sphingomonadales	204457|Sphingomonadales	G	Aldolase	-	-	4.1.2.21	ko:K01631	ko00052,ko01100,map00052,map01100	M00552	R01064	RC00307,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
SRD2_k127_4252993_13	1123267.JONN01000001_gene512	8.044e-123	407.0	COG0673@1|root,COG0673@2|Bacteria,1MW0Q@1224|Proteobacteria,2TQR0@28211|Alphaproteobacteria,2K0NU@204457|Sphingomonadales	204457|Sphingomonadales	S	Galactose 1-dehydrogenase	-	-	1.1.1.48	ko:K00035	ko00052,ko01100,map00052,map01100	-	R01094,R01097	RC00161	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
SRD2_k127_4252993_18	1123267.JONN01000001_gene2389	3.979e-82	280.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2TQXG@28211|Alphaproteobacteria,2K1GD@204457|Sphingomonadales	204457|Sphingomonadales	K	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
SRD2_k127_4252993_10	1123267.JONN01000001_gene2388	6.829e-162	515.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2TT2U@28211|Alphaproteobacteria,2K057@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRD2_k127_4252993_16	1123267.JONN01000001_gene2387	2.934e-85	284.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2TR8J@28211|Alphaproteobacteria,2K18B@204457|Sphingomonadales	204457|Sphingomonadales	S	Aminomethyltransferase	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T
SRD2_k127_4254579_9	392499.Swit_2821	2.485e-37	159.0	COG0666@1|root,COG0666@2|Bacteria,1RFFD@1224|Proteobacteria,2U8T6@28211|Alphaproteobacteria,2K4S6@204457|Sphingomonadales	204457|Sphingomonadales	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4,Ank_5
SRD2_k127_4254579_4	1123267.JONN01000001_gene2168	2.808e-67	231.0	COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,2U99S@28211|Alphaproteobacteria,2K4JE@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0260 family	-	-	-	ko:K09160	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SRD2_k127_4254579_5	1123267.JONN01000001_gene2169	4.028e-61	221.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2U1JG@28211|Alphaproteobacteria,2K287@204457|Sphingomonadales	204457|Sphingomonadales	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
SRD2_k127_4254579_0	1123267.JONN01000001_gene2170	1.916e-288	900.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,2K0HX@204457|Sphingomonadales	204457|Sphingomonadales	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRD2_k127_4254579_8	1123267.JONN01000001_gene2172	6.263e-40	154.0	2AGZR@1|root,3178H@2|Bacteria,1NJBM@1224|Proteobacteria,2UJXF@28211|Alphaproteobacteria,2K8AT@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4402
SRD2_k127_4254579_10	317655.Sala_2858	5.31e-16	85.0	2EKFG@1|root,33E5M@2|Bacteria,1NJ6W@1224|Proteobacteria,2UJAN@28211|Alphaproteobacteria,2K84W@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4402
SRD2_k127_4254579_3	1123267.JONN01000001_gene2123	3.639e-87	298.0	COG3121@1|root,COG3121@2|Bacteria,1RFSJ@1224|Proteobacteria,2U926@28211|Alphaproteobacteria,2K4YS@204457|Sphingomonadales	204457|Sphingomonadales	NU	COG3121 P pilus assembly protein, chaperone PapD	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4254579_1	1123267.JONN01000001_gene2122	1.384e-272	866.0	COG3188@1|root,COG3188@2|Bacteria,1R6ZJ@1224|Proteobacteria,2U0NW@28211|Alphaproteobacteria,2K2TI@204457|Sphingomonadales	204457|Sphingomonadales	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRD2_k127_4254579_7	1123267.JONN01000001_gene2120	3.26e-46	185.0	2E521@1|root,32ZVA@2|Bacteria,1RF95@1224|Proteobacteria,2U8QW@28211|Alphaproteobacteria,2K2DR@204457|Sphingomonadales	204457|Sphingomonadales	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
SRD2_k127_4254579_2	1123267.JONN01000001_gene2119	1.211e-115	376.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2TS9Y@28211|Alphaproteobacteria,2JZVB@204457|Sphingomonadales	204457|Sphingomonadales	D	cell division	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRD2_k127_4254579_6	1030157.AFMP01000014_gene3385	3.412e-48	183.0	COG2177@1|root,COG2177@2|Bacteria,1MXKQ@1224|Proteobacteria,2TSNT@28211|Alphaproteobacteria,2K43P@204457|Sphingomonadales	204457|Sphingomonadales	D	Cell division protein	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRD2_k127_4262111_1	1040986.ATYO01000003_gene5825	5.732e-60	213.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,43H3D@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Dehydrogenase	lldD	-	1.1.2.3	ko:K00101	ko00620,ko01100,map00620,map01100	-	R00196	RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRD2_k127_4262111_0	716928.AJQT01000058_gene5368	0.0	1209.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSN5@28211|Alphaproteobacteria,4B8XS@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SRD2_k127_4262111_2	745310.G432_11310	1.286e-39	156.0	29Y62@1|root,30JZF@2|Bacteria,1NKNK@1224|Proteobacteria,2UKHF@28211|Alphaproteobacteria,2K7QH@204457|Sphingomonadales	204457|Sphingomonadales	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
SRD2_k127_4311786_7	1123240.ATVO01000004_gene1270	6.169e-104	341.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2TRV3@28211|Alphaproteobacteria,2K21F@204457|Sphingomonadales	204457|Sphingomonadales	T	Phosphate starvation-inducible protein PhoH	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRD2_k127_4311786_10	1123267.JONN01000001_gene810	3.096e-57	204.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2UBXV@28211|Alphaproteobacteria,2K4EE@204457|Sphingomonadales	204457|Sphingomonadales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRD2_k127_4311786_6	1123267.JONN01000001_gene809	2.079e-117	384.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TVFA@28211|Alphaproteobacteria,2K03F@204457|Sphingomonadales	204457|Sphingomonadales	S	COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC
SRD2_k127_4311786_11	1122970.AUHC01000013_gene1074	2.934e-53	207.0	COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,2U78G@28211|Alphaproteobacteria,2K4FM@204457|Sphingomonadales	204457|Sphingomonadales	S	dioxygenase of extradiol dioxygenase family	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRD2_k127_4311786_1	1123267.JONN01000001_gene808	2.517e-165	534.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2TQRC@28211|Alphaproteobacteria,2K1Y8@204457|Sphingomonadales	204457|Sphingomonadales	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRD2_k127_4311786_0	317655.Sala_3139	3.888e-191	604.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2TR4P@28211|Alphaproteobacteria,2K02E@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRD2_k127_4311786_12	491916.RHECIAT_CH0001140	3.611e-38	149.0	COG4244@1|root,COG4244@2|Bacteria,1RKBB@1224|Proteobacteria,2UA11@28211|Alphaproteobacteria,4BFTR@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SRD2_k127_4311786_4	1123267.JONN01000001_gene804	9.745e-119	384.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2TUU9@28211|Alphaproteobacteria,2K0BM@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
SRD2_k127_4311786_3	1090319.KE386571_gene103	1.723e-142	463.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2K0QG@204457|Sphingomonadales	204457|Sphingomonadales	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRD2_k127_4311786_2	1123267.JONN01000001_gene801	2.662e-146	471.0	COG3424@1|root,COG3424@2|Bacteria,1MUDX@1224|Proteobacteria,2TRTX@28211|Alphaproteobacteria,2K1FI@204457|Sphingomonadales	204457|Sphingomonadales	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
SRD2_k127_4311786_9	1123267.JONN01000001_gene800	5.47e-58	208.0	COG1755@1|root,COG1755@2|Bacteria,1RERZ@1224|Proteobacteria,2U77M@28211|Alphaproteobacteria,2K4HJ@204457|Sphingomonadales	204457|Sphingomonadales	S	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
SRD2_k127_4311786_8	745310.G432_07650	1.304e-64	226.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2TS4E@28211|Alphaproteobacteria,2K45N@204457|Sphingomonadales	204457|Sphingomonadales	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRD2_k127_4311786_5	1219049.SP5_053_00060	9.149e-118	391.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2TRQN@28211|Alphaproteobacteria,2K1KF@204457|Sphingomonadales	204457|Sphingomonadales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
SRD2_k127_4544331_0	317655.Sala_0472	3.788e-278	877.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2K0BI@204457|Sphingomonadales	204457|Sphingomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRD2_k127_4544331_2	1123267.JONN01000001_gene387	3.178e-153	494.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,2U18A@28211|Alphaproteobacteria,2K0EM@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRD2_k127_4544331_10	1123267.JONN01000001_gene388	5.979e-29	117.0	COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,2UBU4@28211|Alphaproteobacteria,2K6WX@204457|Sphingomonadales	204457|Sphingomonadales	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRD2_k127_4544331_6	685778.AORL01000019_gene1695	2.348e-66	238.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria,2K40S@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SRD2_k127_4544331_9	1550073.JROH01000008_gene1807	1.14e-31	128.0	COG2261@1|root,COG2261@2|Bacteria,1N8B3@1224|Proteobacteria,2UKNY@28211|Alphaproteobacteria,2K64H@204457|Sphingomonadales	204457|Sphingomonadales	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRD2_k127_4544331_7	1174684.EBMC1_00345	6.62e-51	181.0	2AMHV@1|root,31CDG@2|Bacteria,1RGVA@1224|Proteobacteria,2U98Q@28211|Alphaproteobacteria,2K54G@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1153
SRD2_k127_4544331_1	1123267.JONN01000001_gene392	7.299e-180	569.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2TQU7@28211|Alphaproteobacteria,2K1HV@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRD2_k127_4544331_8	13689.BV96_01501	5.169e-50	189.0	COG4119@1|root,COG4119@2|Bacteria,1RHCE@1224|Proteobacteria,2U8N1@28211|Alphaproteobacteria,2K5NT@204457|Sphingomonadales	204457|Sphingomonadales	L	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRD2_k127_4544331_5	1123267.JONN01000001_gene394	3.832e-89	302.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,2U4TZ@28211|Alphaproteobacteria,2K01E@204457|Sphingomonadales	204457|Sphingomonadales	S	PhzC PhzF	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRD2_k127_4544331_3	1123267.JONN01000001_gene395	1.616e-123	407.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2TT78@28211|Alphaproteobacteria,2K09U@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	ko:K13283	-	-	-	-	ko00000,ko02000	2.A.4.7.1	-	-	Cation_efflux,ZT_dimer
SRD2_k127_4544331_4	1007104.SUS17_3700	4.567e-93	309.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2TT1U@28211|Alphaproteobacteria,2K0J3@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SRD2_k127_4545372_2	1123267.JONN01000001_gene579	6.475e-99	324.0	2AFT8@1|root,315VF@2|Bacteria,1RAPJ@1224|Proteobacteria,2U6M6@28211|Alphaproteobacteria,2K2CZ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4545372_5	1123267.JONN01000001_gene580	2.162e-57	204.0	2D94Q@1|root,32TSM@2|Bacteria,1R37H@1224|Proteobacteria,2TZZ1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NT5C
SRD2_k127_4545372_1	1123267.JONN01000001_gene582	1.749e-197	625.0	COG0773@1|root,COG0773@2|Bacteria,1MVCG@1224|Proteobacteria,2TTDN@28211|Alphaproteobacteria,2K0S4@204457|Sphingomonadales	204457|Sphingomonadales	M	UDP-N-acetylmuramate-alanine ligase	-	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRD2_k127_4545372_0	745310.G432_10805	1.245e-237	748.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria,2K1RR@204457|Sphingomonadales	204457|Sphingomonadales	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SRD2_k127_4545372_3	1123267.JONN01000001_gene583	1.254e-94	317.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,2U0U5@28211|Alphaproteobacteria,2K08M@204457|Sphingomonadales	204457|Sphingomonadales	V	proteins, homologs of microcin C7 resistance protein MccF	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
SRD2_k127_4545372_6	1449076.JOOE01000001_gene2602	7.954e-32	130.0	COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,2UC9T@28211|Alphaproteobacteria,2KCA8@204457|Sphingomonadales	204457|Sphingomonadales	B	SWI complex, BAF60b domains	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
SRD2_k127_4545372_4	1123269.NX02_23225	2.195e-63	225.0	COG1051@1|root,COG1051@2|Bacteria,1QUPQ@1224|Proteobacteria,2TW3M@28211|Alphaproteobacteria,2K0RT@204457|Sphingomonadales	204457|Sphingomonadales	F	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRD2_k127_4562345_2	69279.BG36_05460	1.788e-298	923.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TZTW@28211|Alphaproteobacteria,43MN8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.5.8.1,1.5.8.2	ko:K00317	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R01588,R02511	RC00185,RC00556,RC00557,RC00732	ko00000,ko00001,ko01000	-	-	-	NAD_binding_8,Oxidored_FMN,Pyr_redox_2
SRD2_k127_4562345_3	69279.BG36_05465	1.708e-174	557.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,43GR9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRD2_k127_4562345_0	1163409.UUA_08346	0.0	1170.0	COG0823@1|root,COG0823@2|Bacteria,1MWYK@1224|Proteobacteria,1RXYW@1236|Gammaproteobacteria,1XD03@135614|Xanthomonadales	135614|Xanthomonadales	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRD2_k127_4562345_4	1185876.BN8_02716	1.504e-70	250.0	COG0604@1|root,COG0604@2|Bacteria,4NHHT@976|Bacteroidetes,47N64@768503|Cytophagia	976|Bacteroidetes	C	COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_2,ADH_zinc_N_2
SRD2_k127_4562345_5	639283.Snov_2319	9.025e-53	194.0	COG0671@1|root,COG0671@2|Bacteria,1PX74@1224|Proteobacteria,2TUV9@28211|Alphaproteobacteria,3F16K@335928|Xanthobacteraceae	28211|Alphaproteobacteria	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
SRD2_k127_4562345_7	1500259.JQLD01000015_gene4507	2.974e-24	113.0	COG3230@1|root,COG3230@2|Bacteria,1NDMX@1224|Proteobacteria,2UFQI@28211|Alphaproteobacteria,4BDV5@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	heme oxygenase	-	-	1.14.99.58	ko:K07215	ko00860,map00860	-	-	-	ko00000,ko00001,ko01000	-	-	-	-
SRD2_k127_4562345_1	1112214.AHIS01000095_gene661	0.0	1111.0	COG3279@1|root,COG4251@1|root,COG3279@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2TWHG@28211|Alphaproteobacteria,2KEPG@204457|Sphingomonadales	204457|Sphingomonadales	T	Phytochrome region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c_2,HWE_HK,HisKA_2,PAS_2,PHY,Response_reg
SRD2_k127_4562345_8	1379698.RBG1_1C00001G0762	2.768e-16	83.0	2EMPS@1|root,33FC7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4562345_6	1123267.JONN01000001_gene1852	1.616e-40	163.0	COG2202@1|root,COG3920@1|root,COG2202@2|Bacteria,COG3920@2|Bacteria,1NWNJ@1224|Proteobacteria,2TZHN@28211|Alphaproteobacteria,2KETX@204457|Sphingomonadales	204457|Sphingomonadales	T	HWE histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HWE_HK
SRD2_k127_4562345_10	1549858.MC45_02295	1.531e-14	74.0	COG3847@1|root,COG3847@2|Bacteria,1Q1G3@1224|Proteobacteria,2V11R@28211|Alphaproteobacteria,2K7TI@204457|Sphingomonadales	204457|Sphingomonadales	U	Flp pilus assembly protein, pilin Flp	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
SRD2_k127_4562345_9	1549858.MC45_02295	2.692e-15	77.0	COG3847@1|root,COG3847@2|Bacteria,1Q1G3@1224|Proteobacteria,2V11R@28211|Alphaproteobacteria,2K7TI@204457|Sphingomonadales	204457|Sphingomonadales	U	Flp pilus assembly protein, pilin Flp	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
SRD2_k127_4562345_11	316057.RPD_2430	3.399e-14	82.0	COG4251@1|root,COG5278@1|root,COG4251@2|Bacteria,COG5278@2|Bacteria,1NSQ1@1224|Proteobacteria,2TSPY@28211|Alphaproteobacteria,3JU59@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,MHYT,PAS_3
SRD2_k127_4582447_6	1112214.AHIS01000047_gene1995	3.423e-19	92.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2TR70@28211|Alphaproteobacteria,2K10R@204457|Sphingomonadales	204457|Sphingomonadales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRD2_k127_4582447_1	1123267.JONN01000001_gene2130	1.679e-189	603.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRCI@28211|Alphaproteobacteria,2K0M4@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX2	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRD2_k127_4582447_0	1123267.JONN01000001_gene2129	1.455e-229	722.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2TRAU@28211|Alphaproteobacteria,2K0R3@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRD2_k127_4582447_2	1123267.JONN01000001_gene2128	8.729e-163	520.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2TR4Y@28211|Alphaproteobacteria,2K0MQ@204457|Sphingomonadales	204457|Sphingomonadales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRD2_k127_4582447_4	1110502.TMO_2217	6.313e-58	208.0	COG2135@1|root,COG2135@2|Bacteria,1MY65@1224|Proteobacteria,2U39X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRD2_k127_4582447_5	1248916.ANFY01000010_gene419	7.594e-57	200.0	COG1917@1|root,COG1917@2|Bacteria,1RHHY@1224|Proteobacteria,2UCCW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_3
SRD2_k127_4582447_3	1123267.JONN01000001_gene2105	1.04e-58	211.0	COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,2TUR9@28211|Alphaproteobacteria,2K4MT@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD2_k127_4582447_7	161528.ED21_20104	7.68e-06	53.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2UF6K@28211|Alphaproteobacteria,2K5YR@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRD2_k127_4846224_8	1123267.JONN01000001_gene539	3.771e-88	299.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2TRXJ@28211|Alphaproteobacteria,2K28T@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRD2_k127_4846224_16	494419.ALPM01000024_gene272	0.000307	51.0	COG5180@1|root,COG5180@2|Bacteria,2GKJ7@201174|Actinobacteria,1WCEY@1268|Micrococcaceae	201174|Actinobacteria	A	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
SRD2_k127_4846224_11	1030157.AFMP01000062_gene3529	2.626e-70	243.0	COG0454@1|root,COG0454@2|Bacteria,1RDGT@1224|Proteobacteria,2TRF5@28211|Alphaproteobacteria,2K22G@204457|Sphingomonadales	204457|Sphingomonadales	K	N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD2_k127_4846224_2	1219049.SP5_018_00860	4.579e-141	452.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2TQNC@28211|Alphaproteobacteria,2K084@204457|Sphingomonadales	204457|Sphingomonadales	H	coproporphyrinogen III oxidase	hemF	-	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
SRD2_k127_4846224_17	579138.Zymop_0247	0.0003509	52.0	COG5126@1|root,COG5126@2|Bacteria,1NH5D@1224|Proteobacteria,2UJHN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	DTZ	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
SRD2_k127_4846224_14	1123267.JONN01000001_gene1032	1.699e-28	116.0	2B3XE@1|root,31WMD@2|Bacteria,1P4DI@1224|Proteobacteria,2UW3Y@28211|Alphaproteobacteria,2KBX1@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_CI_repr
SRD2_k127_4846224_12	1123267.JONN01000001_gene1033	1.563e-54	196.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria,2K4IQ@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRD2_k127_4846224_7	1123267.JONN01000001_gene1034	3.179e-97	325.0	COG1213@1|root,COG1213@2|Bacteria,1RB54@1224|Proteobacteria,2U5XC@28211|Alphaproteobacteria,2K2S2@204457|Sphingomonadales	204457|Sphingomonadales	M	Nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
SRD2_k127_4846224_10	1297865.APJD01000015_gene3469	1.523e-79	271.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,3JSHJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH,Thioesterase
SRD2_k127_4846224_1	1081640.AGFU01000025_gene2518	9.726e-154	488.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2TQTH@28211|Alphaproteobacteria,2K0AR@204457|Sphingomonadales	204457|Sphingomonadales	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRD2_k127_4846224_6	1174684.EBMC1_13998	4.949e-102	343.0	2C59N@1|root,30HSI@2|Bacteria,1R378@1224|Proteobacteria,2TZYT@28211|Alphaproteobacteria,2KEWA@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4846224_5	1123267.JONN01000001_gene1037	2.311e-111	364.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2TU5C@28211|Alphaproteobacteria,2K05Q@204457|Sphingomonadales	204457|Sphingomonadales	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SRD2_k127_4846224_3	1267533.KB906740_gene284	1.913e-137	463.0	COG1505@1|root,COG1505@2|Bacteria,3Y2UH@57723|Acidobacteria,2JHQ3@204432|Acidobacteriia	204432|Acidobacteriia	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRD2_k127_4846224_15	272568.GDI3437	1.178e-05	51.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,2UF4X@28211|Alphaproteobacteria,2JTUA@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein conserved in bacteria	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
SRD2_k127_4846224_13	1123267.JONN01000001_gene1039	1.813e-44	166.0	COG1846@1|root,COG1846@2|Bacteria,1MZY5@1224|Proteobacteria,2U9EE@28211|Alphaproteobacteria,2K62J@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRD2_k127_4846224_4	1123267.JONN01000001_gene1040	1.508e-115	383.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,2K1WC@204457|Sphingomonadales	204457|Sphingomonadales	V	Secretion protein, HlyD	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRD2_k127_4846224_0	1123267.JONN01000001_gene1041	1.211e-220	694.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2TVXT@28211|Alphaproteobacteria,2JZYF@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
SRD2_k127_4846224_18	1174684.EBMC1_07375	0.0006609	49.0	COG1872@1|root,COG1872@2|Bacteria	2|Bacteria	I	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRD2_k127_4846224_9	670292.JH26_24625	2.422e-85	286.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,1JT1V@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRD2_k127_4921242_1	1123267.JONN01000001_gene1413	2.872e-150	481.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,2U0RR@28211|Alphaproteobacteria,2K0B9@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the agmatine deiminase family	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
SRD2_k127_4921242_3	161528.ED21_29038	2.937e-58	210.0	COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,2TSWP@28211|Alphaproteobacteria,2K2QW@204457|Sphingomonadales	204457|Sphingomonadales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRD2_k127_4921242_0	1123267.JONN01000001_gene1415	3.608e-159	504.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,2TVCS@28211|Alphaproteobacteria,2K0V3@204457|Sphingomonadales	204457|Sphingomonadales	S	N-carbamoylputrescine amidase	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRD2_k127_4921242_2	1123267.JONN01000001_gene1418	1.179e-92	312.0	COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,2TSUP@28211|Alphaproteobacteria,2K0J4@204457|Sphingomonadales	204457|Sphingomonadales	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRD2_k127_4921242_4	1123267.JONN01000001_gene1419	3.472e-50	183.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2U8D6@28211|Alphaproteobacteria,2K57H@204457|Sphingomonadales	204457|Sphingomonadales	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SRD2_k127_4968748_1	1209072.ALBT01000013_gene3573	1.572e-163	526.0	COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,1RQX9@1236|Gammaproteobacteria,1FHW2@10|Cellvibrio	1236|Gammaproteobacteria	G	Major Facilitator Superfamily	gluP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
SRD2_k127_4968748_7	1123269.NX02_24485	2.021e-12	73.0	2B1VU@1|root,31UBX@2|Bacteria,1QS6Q@1224|Proteobacteria,2V693@28211|Alphaproteobacteria,2K5PD@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4968748_2	1121033.AUCF01000009_gene1136	2.434e-157	507.0	COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria,2TTWR@28211|Alphaproteobacteria,2JQPS@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
SRD2_k127_4968748_5	509190.Cseg_1268	3.089e-70	248.0	COG0726@1|root,COG0726@2|Bacteria,1NBB8@1224|Proteobacteria,2UP9U@28211|Alphaproteobacteria,2KJYG@204458|Caulobacterales	204458|Caulobacterales	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRD2_k127_4968748_0	194867.ALBQ01000038_gene2377	7.919e-212	667.0	COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,2U3NF@28211|Alphaproteobacteria,2KEH5@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRD2_k127_4968748_4	1449076.JOOE01000001_gene2849	1.341e-106	353.0	COG3386@1|root,COG3386@2|Bacteria,1MWTR@1224|Proteobacteria,2TV5X@28211|Alphaproteobacteria,2K16R@204457|Sphingomonadales	204457|Sphingomonadales	G	Gluconolactonase	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
SRD2_k127_4968748_3	1123267.JONN01000001_gene1933	1.015e-129	430.0	COG5388@1|root,COG5388@2|Bacteria,1R74W@1224|Proteobacteria,2TUTW@28211|Alphaproteobacteria,2K1EC@204457|Sphingomonadales	204457|Sphingomonadales	S	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_4968748_6	1030157.AFMP01000040_gene1347	1.35e-32	132.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,2K0WP@204457|Sphingomonadales	204457|Sphingomonadales	E	glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRD2_k127_5011817_22	1123267.JONN01000002_gene166	4.165e-25	109.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria,2K6WZ@204457|Sphingomonadales	204457|Sphingomonadales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRD2_k127_5011817_7	1123267.JONN01000002_gene165	2.876e-110	366.0	COG3820@1|root,COG3820@2|Bacteria,1MVR2@1224|Proteobacteria,2TT8Z@28211|Alphaproteobacteria,2K0D3@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09987	-	-	-	-	ko00000	-	-	-	DUF1013
SRD2_k127_5011817_11	1502850.FG91_03755	4.21e-87	292.0	COG0625@1|root,COG0625@2|Bacteria,1REDI@1224|Proteobacteria,2TR9W@28211|Alphaproteobacteria,2K0R9@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the GST superfamily	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
SRD2_k127_5011817_5	1470591.BW41_00913	6.534e-142	457.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TR1J@28211|Alphaproteobacteria,2K115@204457|Sphingomonadales	204457|Sphingomonadales	C	NADPH quinone	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRD2_k127_5011817_24	1550073.JROH01000075_gene2923	1.735e-09	64.0	COG5509@1|root,COG5509@2|Bacteria,1NG8P@1224|Proteobacteria,2UJB2@28211|Alphaproteobacteria,2K7YT@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1192)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1192
SRD2_k127_5011817_1	627192.SLG_33040	0.0	1256.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2TQUZ@28211|Alphaproteobacteria,2K0MN@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRD2_k127_5011817_21	1123267.JONN01000002_gene159	7.107e-29	124.0	2B9KF@1|root,322YP@2|Bacteria,1P8XS@1224|Proteobacteria,2UX7H@28211|Alphaproteobacteria,2K64E@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5011817_8	1121939.L861_23050	6.731e-104	343.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,1RYXI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRD2_k127_5011817_19	1449076.JOOE01000003_gene3772	4.174e-41	158.0	COG3832@1|root,COG3832@2|Bacteria,1RHJJ@1224|Proteobacteria,2U6I2@28211|Alphaproteobacteria,2K7CQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRD2_k127_5011817_15	1449076.JOOE01000003_gene3771	3.632e-55	200.0	COG3832@1|root,COG3832@2|Bacteria,1N4FU@1224|Proteobacteria,2UD8Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRD2_k127_5011817_18	1449076.JOOE01000003_gene3769	4.061e-44	172.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,2U960@28211|Alphaproteobacteria,2KD85@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRD2_k127_5011817_2	745310.G432_02550	3.72e-279	874.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TRTE@28211|Alphaproteobacteria,2K0PD@204457|Sphingomonadales	204457|Sphingomonadales	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRD2_k127_5011817_4	685778.AORL01000004_gene3475	1.434e-220	700.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,2TVJ5@28211|Alphaproteobacteria,2K04D@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRD2_k127_5011817_12	1449076.JOOE01000004_gene510	9.019e-87	291.0	COG0625@1|root,COG0625@2|Bacteria,1RA05@1224|Proteobacteria,2TS58@28211|Alphaproteobacteria,2K1M0@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
SRD2_k127_5011817_10	1207055.C100_07790	1.218e-92	311.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2TRSF@28211|Alphaproteobacteria,2K14K@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
SRD2_k127_5011817_16	530564.Psta_0527	1.391e-52	199.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD2_k127_5011817_9	161528.ED21_20789	3.446e-95	323.0	COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,2UUEK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Protein phosphatase 2A homologues, catalytic domain.	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRD2_k127_5011817_13	291985.CCSI01000007_gene460	1.206e-70	254.0	28M5H@1|root,2ZAJ9@2|Bacteria,1RJY2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5011817_14	161528.ED21_20779	8.476e-57	205.0	2FGC9@1|root,3488G@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
SRD2_k127_5011817_6	158500.BV97_02672	4.544e-112	367.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,2K0KF@204457|Sphingomonadales	204457|Sphingomonadales	S	Polyphosphate kinase 2 (PPK2)	ppk2	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
SRD2_k127_5011817_20	1123501.KB902287_gene1963	5.04e-34	136.0	COG1051@1|root,COG1051@2|Bacteria,1N0YW@1224|Proteobacteria,2UC2E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRD2_k127_5011817_17	1123267.JONN01000002_gene153	8.463e-52	188.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2U7FV@28211|Alphaproteobacteria,2K3F8@204457|Sphingomonadales	204457|Sphingomonadales	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRD2_k127_5011817_3	1144307.PMI04_03535	6.464e-252	793.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2TUZZ@28211|Alphaproteobacteria,2K9N7@204457|Sphingomonadales	204457|Sphingomonadales	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRD2_k127_5011817_0	1123267.JONN01000001_gene1294	0.0	1635.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,2K0VM@204457|Sphingomonadales	204457|Sphingomonadales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRD2_k127_5011817_23	526225.Gobs_2287	8.709e-15	81.0	COG0400@1|root,COG0400@2|Bacteria,2IM4S@201174|Actinobacteria,4EVK0@85013|Frankiales	201174|Actinobacteria	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase_phd
SRD2_k127_5082392_26	1123267.JONN01000001_gene2065	1.074e-134	437.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TRNY@28211|Alphaproteobacteria,2JZVI@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRD2_k127_5082392_47	1123267.JONN01000001_gene2066	5.501e-74	258.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,2TTK9@28211|Alphaproteobacteria,2K20T@204457|Sphingomonadales	204457|Sphingomonadales	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRD2_k127_5082392_28	1123267.JONN01000001_gene2067	1.879e-120	392.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2TS8T@28211|Alphaproteobacteria,2K0E3@204457|Sphingomonadales	204457|Sphingomonadales	O	ABC-type transport system involved in Fe-S cluster assembly, ATPase component	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRD2_k127_5082392_68	1123267.JONN01000001_gene2068	2.571e-24	108.0	2AMGD@1|root,31CBX@2|Bacteria,1Q8D5@1224|Proteobacteria,2VEJQ@28211|Alphaproteobacteria,2K80X@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5082392_10	1123267.JONN01000001_gene2069	4.47e-283	882.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,2TRU6@28211|Alphaproteobacteria,2K196@204457|Sphingomonadales	204457|Sphingomonadales	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRD2_k127_5082392_56	392499.Swit_2919	5.402e-46	169.0	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,2UAVK@28211|Alphaproteobacteria,2K421@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRD2_k127_5082392_25	1123267.JONN01000001_gene2071	1.692e-137	448.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2TRF8@28211|Alphaproteobacteria,2K1QF@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRD2_k127_5082392_13	279238.Saro_0192	6.143e-215	684.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,2K0PZ@204457|Sphingomonadales	204457|Sphingomonadales	E	gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRD2_k127_5082392_11	1123267.JONN01000001_gene1917	4.074e-273	852.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2TSSI@28211|Alphaproteobacteria,2K12J@204457|Sphingomonadales	204457|Sphingomonadales	I	synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRD2_k127_5082392_72	1123267.JONN01000001_gene1918	6.967e-22	108.0	2FB68@1|root,30QV6@2|Bacteria,1NWWK@1224|Proteobacteria,2US5H@28211|Alphaproteobacteria,2K6YE@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5082392_39	1112216.JH594425_gene1623	1.935e-93	312.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2TSVS@28211|Alphaproteobacteria,2K0DY@204457|Sphingomonadales	204457|Sphingomonadales	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
SRD2_k127_5082392_34	1030157.AFMP01000016_gene2495	2.086e-110	370.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2TUT7@28211|Alphaproteobacteria,2K14V@204457|Sphingomonadales	204457|Sphingomonadales	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
SRD2_k127_5082392_48	1123267.JONN01000001_gene1920	2.781e-73	248.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,2K4E9@204457|Sphingomonadales	204457|Sphingomonadales	E	COG0346 Lactoylglutathione lyase and related lyases	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRD2_k127_5082392_42	685035.ADAE01000018_gene694	1.47e-90	308.0	COG2859@1|root,COG2859@2|Bacteria,1QU0K@1224|Proteobacteria,2U5D2@28211|Alphaproteobacteria,2K0TS@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
SRD2_k127_5082392_69	1449076.JOOE01000004_gene346	5.111e-24	110.0	COG0457@1|root,COG0457@2|Bacteria,1RK4Q@1224|Proteobacteria,2UBBB@28211|Alphaproteobacteria,2KET6@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5082392_43	13689.BV96_02173	2.401e-87	294.0	COG1073@1|root,COG1073@2|Bacteria,1MX88@1224|Proteobacteria,2TSRE@28211|Alphaproteobacteria,2K1F6@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRD2_k127_5082392_41	1247963.JPHU01000008_gene2882	1.022e-90	310.0	COG2850@1|root,COG2850@2|Bacteria,1MUAC@1224|Proteobacteria,2U0YE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	A domain family that is part of the cupin metalloenzyme superfamily.	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
SRD2_k127_5082392_23	1123267.JONN01000001_gene638	8.3e-146	469.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria,2K1KY@204457|Sphingomonadales	204457|Sphingomonadales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRD2_k127_5082392_53	1123267.JONN01000001_gene2027	1.704e-51	186.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,2U768@28211|Alphaproteobacteria,2K4NB@204457|Sphingomonadales	204457|Sphingomonadales	O	redox protein, regulator of disulfide bond formation	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRD2_k127_5082392_70	1112212.JH584235_gene3156	2.171e-23	109.0	COG1476@1|root,COG1476@2|Bacteria,1N6SS@1224|Proteobacteria,2UFFG@28211|Alphaproteobacteria,2K6RT@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
SRD2_k127_5082392_57	1112212.JH584235_gene3158	8.376e-45	168.0	2E2TJ@1|root,335ZH@2|Bacteria,1NE5E@1224|Proteobacteria,2UHE1@28211|Alphaproteobacteria,2K6CV@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5082392_44	113395.AXAI01000002_gene5399	2.321e-86	290.0	COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria,2VG1Y@28211|Alphaproteobacteria,3K6HR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
SRD2_k127_5082392_4	627192.SLG_01460	0.0	1120.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2TQWI@28211|Alphaproteobacteria,2K14B@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRD2_k127_5082392_40	1123267.JONN01000001_gene2054	2.009e-91	305.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2U58Z@28211|Alphaproteobacteria,2K0EN@204457|Sphingomonadales	204457|Sphingomonadales	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRD2_k127_5082392_6	1123267.JONN01000001_gene2053	0.0	1060.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2TTI2@28211|Alphaproteobacteria,2K0SD@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRD2_k127_5082392_5	1123267.JONN01000001_gene2052	0.0	1103.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria,2K0BN@204457|Sphingomonadales	204457|Sphingomonadales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
SRD2_k127_5082392_1	1123267.JONN01000001_gene2051	0.0	1222.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2TQRR@28211|Alphaproteobacteria,2K09S@204457|Sphingomonadales	204457|Sphingomonadales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRD2_k127_5082392_3	1123267.JONN01000001_gene2050	0.0	1187.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,2JZY4@204457|Sphingomonadales	204457|Sphingomonadales	C	Malic enzyme	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
SRD2_k127_5082392_2	1123267.JONN01000001_gene2049	0.0	1216.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2TQNY@28211|Alphaproteobacteria,2K15Q@204457|Sphingomonadales	204457|Sphingomonadales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRD2_k127_5082392_77	629773.AORY01000004_gene185	0.0002746	48.0	2AM78@1|root,31C1V@2|Bacteria,1Q805@1224|Proteobacteria,2VE5V@28211|Alphaproteobacteria,2K70U@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5082392_58	1219045.BV98_001785	8.428e-45	171.0	COG1733@1|root,COG1733@2|Bacteria,1RIZT@1224|Proteobacteria,2U7SS@28211|Alphaproteobacteria,2K4MD@204457|Sphingomonadales	204457|Sphingomonadales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRD2_k127_5082392_59	745310.G432_15545	2.273e-43	165.0	COG0847@1|root,COG0847@2|Bacteria,1R1PR@1224|Proteobacteria,2TZ52@28211|Alphaproteobacteria,2KER2@204457|Sphingomonadales	204457|Sphingomonadales	L	3' exoribonuclease, RNase T-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF5051
SRD2_k127_5082392_76	1479239.JQMU01000001_gene1412	5.772e-10	64.0	2DCTG@1|root,2ZF9T@2|Bacteria,1N82Z@1224|Proteobacteria,2UGXI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5082392_0	1123267.JONN01000001_gene2428	0.0	1230.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,2K0I6@204457|Sphingomonadales	204457|Sphingomonadales	L	helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRD2_k127_5082392_18	1470591.BW41_03929	6.033e-174	550.0	COG1236@1|root,COG1236@2|Bacteria,1MV7U@1224|Proteobacteria,2TQU5@28211|Alphaproteobacteria,2K1G9@204457|Sphingomonadales	204457|Sphingomonadales	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Lactamase_B
SRD2_k127_5082392_51	153721.MYP_3865	2.955e-63	229.0	COG0642@1|root,COG2199@1|root,COG4251@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,4NE3J@976|Bacteroidetes,47JCX@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRD2_k127_5082392_62	392499.Swit_0420	8.375e-39	156.0	2C38E@1|root,33Z2K@2|Bacteria,1MY9G@1224|Proteobacteria,2U9BB@28211|Alphaproteobacteria,2K5SY@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5082392_12	1123267.JONN01000001_gene2459	3.281e-219	706.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2TRIJ@28211|Alphaproteobacteria,2K0Q1@204457|Sphingomonadales	204457|Sphingomonadales	G	phosphomannomutase	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRD2_k127_5082392_27	1123267.JONN01000001_gene2458	2.457e-125	406.0	COG1192@1|root,COG1192@2|Bacteria,1MVKR@1224|Proteobacteria,2TRZY@28211|Alphaproteobacteria,2K06A@204457|Sphingomonadales	204457|Sphingomonadales	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MipZ
SRD2_k127_5082392_38	392499.Swit_2788	3.045e-94	316.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2TS2D@28211|Alphaproteobacteria,2K0S2@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRD2_k127_5082392_60	1123267.JONN01000001_gene2456	1.003e-40	153.0	COG0790@1|root,COG0790@2|Bacteria,1N8SR@1224|Proteobacteria,2UFFQ@28211|Alphaproteobacteria,2K5VX@204457|Sphingomonadales	204457|Sphingomonadales	S	FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
SRD2_k127_5082392_75	1449049.JONW01000002_gene2508	3.413e-15	82.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2U758@28211|Alphaproteobacteria,2KGKV@204458|Caulobacterales	204458|Caulobacterales	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SRD2_k127_5082392_30	1219049.SP5_039_00200	6.177e-119	400.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,2K1NT@204457|Sphingomonadales	204457|Sphingomonadales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SRD2_k127_5082392_52	1123267.JONN01000001_gene2450	7.76e-52	188.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2UBYM@28211|Alphaproteobacteria,2K4JS@204457|Sphingomonadales	204457|Sphingomonadales	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRD2_k127_5082392_66	1123267.JONN01000001_gene2449	3.674e-26	113.0	292VB@1|root,3167J@2|Bacteria,1PVMM@1224|Proteobacteria,2V6YV@28211|Alphaproteobacteria,2KC64@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5082392_73	1123267.JONN01000001_gene2448	3.44e-20	92.0	COG1476@1|root,COG1476@2|Bacteria,1N9GC@1224|Proteobacteria,2UIC6@28211|Alphaproteobacteria,2K788@204457|Sphingomonadales	204457|Sphingomonadales	K	Helix-turn-helix domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
SRD2_k127_5082392_24	1123267.JONN01000001_gene2447	8.153e-142	470.0	COG2267@1|root,COG2267@2|Bacteria,1QDFI@1224|Proteobacteria,2U244@28211|Alphaproteobacteria,2K3CZ@204457|Sphingomonadales	204457|Sphingomonadales	I	Protein of unknown function (DUF3089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3089
SRD2_k127_5082392_17	1123267.JONN01000001_gene2446	1.591e-186	587.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2TQNG@28211|Alphaproteobacteria,2K0Y3@204457|Sphingomonadales	204457|Sphingomonadales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRD2_k127_5082392_35	745310.G432_11970	3.681e-109	364.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2K0GT@204457|Sphingomonadales	204457|Sphingomonadales	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRD2_k127_5082392_64	1144307.PMI04_01740	3.748e-33	136.0	COG3087@1|root,COG3087@2|Bacteria	2|Bacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	dacA1	-	3.4.16.4	ko:K01286,ko:K01992,ko:K07258	ko00550,ko01100,map00550,map01100	M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02000	3.A.1	-	-	CD225,Collagen,DUF320,NYN,Peptidase_S11,SPOR
SRD2_k127_5082392_55	1123267.JONN01000001_gene2445	6.72e-47	173.0	COG3791@1|root,COG3791@2|Bacteria,1N023@1224|Proteobacteria,2UC7M@28211|Alphaproteobacteria,2K6R3@204457|Sphingomonadales	204457|Sphingomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRD2_k127_5082392_46	314266.SKA58_05490	1.147e-78	271.0	COG1192@1|root,COG1192@2|Bacteria,1R62T@1224|Proteobacteria,2TUDH@28211|Alphaproteobacteria,2JZW4@204457|Sphingomonadales	204457|Sphingomonadales	D	Chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
SRD2_k127_5082392_61	244582.JQAK01000001_gene1778	8.028e-40	154.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2TSKM@28211|Alphaproteobacteria,47FG4@766|Rickettsiales	766|Rickettsiales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRD2_k127_5082392_50	745310.G432_11955	2.121e-64	232.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2U70Z@28211|Alphaproteobacteria,2K4Q1@204457|Sphingomonadales	204457|Sphingomonadales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRD2_k127_5082392_31	1123267.JONN01000001_gene2441	5.378e-116	377.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2TRSK@28211|Alphaproteobacteria,2K0KW@204457|Sphingomonadales	204457|Sphingomonadales	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRD2_k127_5082392_65	1346791.M529_13315	1.313e-30	122.0	COG3750@1|root,COG3750@2|Bacteria,1N77J@1224|Proteobacteria,2UFX6@28211|Alphaproteobacteria,2K5Z1@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0335 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2312
SRD2_k127_5082392_14	1123267.JONN01000001_gene2437	4.557e-213	672.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2TRFV@28211|Alphaproteobacteria,2K07D@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRD2_k127_5082392_33	1123267.JONN01000001_gene2435	4.158e-112	367.0	COG0406@1|root,COG0406@2|Bacteria,1RAPQ@1224|Proteobacteria,2U0U1@28211|Alphaproteobacteria,2K12D@204457|Sphingomonadales	204457|Sphingomonadales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRD2_k127_5082392_15	1123267.JONN01000001_gene2433	1.065e-194	616.0	COG0438@1|root,COG0562@1|root,COG0438@2|Bacteria,COG0562@2|Bacteria,1MV4H@1224|Proteobacteria,2TTP4@28211|Alphaproteobacteria,2K2QF@204457|Sphingomonadales	204457|Sphingomonadales	M	UDP-galactopyranose mutase	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,Glyco_trans_1_4,NAD_binding_8
SRD2_k127_5082392_21	1123267.JONN01000001_gene2433	8.952e-155	501.0	COG0438@1|root,COG0562@1|root,COG0438@2|Bacteria,COG0562@2|Bacteria,1MV4H@1224|Proteobacteria,2TTP4@28211|Alphaproteobacteria,2K2QF@204457|Sphingomonadales	204457|Sphingomonadales	M	UDP-galactopyranose mutase	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,Glyco_trans_1_4,NAD_binding_8
SRD2_k127_5082392_9	1123267.JONN01000001_gene2432	1.701e-294	908.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRI1@28211|Alphaproteobacteria,2K0V7@204457|Sphingomonadales	204457|Sphingomonadales	I	acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRD2_k127_5082392_54	1381123.AYOD01000044_gene1802	2.23e-51	186.0	COG1764@1|root,COG1764@2|Bacteria,1RI5C@1224|Proteobacteria,2U99X@28211|Alphaproteobacteria,43KYR@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRD2_k127_5082392_67	1174684.EBMC1_11390	2.175e-24	112.0	2BIRS@1|root,32CZA@2|Bacteria,1NENV@1224|Proteobacteria,2UHYW@28211|Alphaproteobacteria,2K7P3@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5082392_49	1123267.JONN01000001_gene2431	1.455e-70	241.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,2U728@28211|Alphaproteobacteria,2K46C@204457|Sphingomonadales	204457|Sphingomonadales	E	methylmalonyl-CoA epimerase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRD2_k127_5082392_37	685778.AORL01000010_gene2855	1.035e-97	336.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2U6NR@28211|Alphaproteobacteria,2K2XA@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
SRD2_k127_5082392_19	627192.SLG_27150	6.948e-173	555.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2KCJR@204457|Sphingomonadales	204457|Sphingomonadales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRD2_k127_5082392_22	745310.G432_10385	1.705e-146	477.0	COG0845@1|root,COG0845@2|Bacteria,1NGI2@1224|Proteobacteria,2U1S9@28211|Alphaproteobacteria,2K0MG@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
SRD2_k127_5082392_32	1449076.JOOE01000001_gene2749	4.79e-114	370.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VEU2@28211|Alphaproteobacteria,2K027@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD2_k127_5082392_7	1144307.PMI04_03252	3.938e-320	1000.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,2U1KH@28211|Alphaproteobacteria,2K128@204457|Sphingomonadales	204457|Sphingomonadales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRD2_k127_5082392_8	745310.G432_10375	2.164e-309	969.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,2U1KH@28211|Alphaproteobacteria,2K128@204457|Sphingomonadales	204457|Sphingomonadales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRD2_k127_5082392_45	1282362.AEAC466_16950	5.043e-85	291.0	COG0598@1|root,COG0598@2|Bacteria,1N5NA@1224|Proteobacteria,2UJ4U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	CorA
SRD2_k127_5082392_20	883078.HMPREF9695_00608	6.746e-164	539.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,3JR0R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,MHYT,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRD2_k127_5082392_16	1304877.KI519401_gene247	2.977e-188	603.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,2TRTV@28211|Alphaproteobacteria,3JV7U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	GvpD gas vesicle protein	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SRD2_k127_5082392_36	1336243.JAEA01000013_gene3237	2.787e-100	336.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2TQXG@28211|Alphaproteobacteria,1JZBT@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	MA20_25280	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
SRD2_k127_5082392_29	1174684.EBMC1_12010	1.33e-119	391.0	COG2941@1|root,COG2941@2|Bacteria,1R4IU@1224|Proteobacteria,2U0RX@28211|Alphaproteobacteria,2K1A0@204457|Sphingomonadales	204457|Sphingomonadales	H	Alternative oxidase	-	-	1.10.3.11	ko:K17893	-	-	R09504	RC00061	ko00000,ko01000	-	-	-	AOX
SRD2_k127_5082392_63	1034943.BN1094_03759	8.338e-36	143.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,1RQ01@1236|Gammaproteobacteria,1JCFA@118969|Legionellales	118969|Legionellales	P	Cytochrome C and Quinol oxidase polypeptide I	norB	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
SRD2_k127_5104092_3	62928.azo0027	8.83e-23	108.0	COG0463@1|root,COG0463@2|Bacteria,1QVBU@1224|Proteobacteria	1224|Proteobacteria	M	N-terminal domain of galactosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD2_k127_5104092_0	1123267.JONN01000001_gene2075	1.872e-298	923.0	COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,2TUN9@28211|Alphaproteobacteria,2K091@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
SRD2_k127_5104092_1	1123267.JONN01000001_gene2074	4.261e-100	343.0	2AFUA@1|root,315WQ@2|Bacteria,1NHGB@1224|Proteobacteria,2TQWW@28211|Alphaproteobacteria,2JZXR@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative transmembrane protein (Alph_Pro_TM)	-	-	-	-	-	-	-	-	-	-	-	-	Alph_Pro_TM
SRD2_k127_5104092_2	1123267.JONN01000001_gene2073	2.112e-92	308.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,2TRIC@28211|Alphaproteobacteria,2K1QQ@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRD2_k127_514654_0	1123267.JONN01000001_gene1960	0.0	1133.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,2K0F8@204457|Sphingomonadales	204457|Sphingomonadales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
SRD2_k127_514654_1	685778.AORL01000009_gene3262	0.0	1035.0	COG2234@1|root,COG2234@2|Bacteria,1R6BQ@1224|Proteobacteria,2U2SM@28211|Alphaproteobacteria,2K3NR@204457|Sphingomonadales	204457|Sphingomonadales	S	Transferrin receptor-like dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28,TFR_dimer
SRD2_k127_514654_3	1449076.JOOE01000003_gene3316	6.956e-28	118.0	2EG8Z@1|root,33A0S@2|Bacteria,1NKBI@1224|Proteobacteria,2UN0S@28211|Alphaproteobacteria,2K67X@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_514654_2	1335760.ASTG01000005_gene1119	2.783e-178	565.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2TS3X@28211|Alphaproteobacteria,2K1H7@204457|Sphingomonadales	204457|Sphingomonadales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
SRD2_k127_5189133_10	1346791.M529_11540	8.676e-46	167.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2TSDZ@28211|Alphaproteobacteria,2JZY9@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRD2_k127_5189133_0	1123267.JONN01000001_gene747	0.0	1152.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2TRMJ@28211|Alphaproteobacteria,2K0GM@204457|Sphingomonadales	204457|Sphingomonadales	L	ATP-dependent helicase	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
SRD2_k127_5189133_9	1496688.ER33_11550	3.243e-57	209.0	28PFD@1|root,2ZC6I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5189133_12	1123267.JONN01000001_gene746	4.396e-37	145.0	2C7TH@1|root,32RJS@2|Bacteria,1MZK8@1224|Proteobacteria,2UC2R@28211|Alphaproteobacteria,2K5XZ@204457|Sphingomonadales	204457|Sphingomonadales	S	ETC complex I subunit	-	-	-	-	-	-	-	-	-	-	-	-	ETC_C1_NDUFA4
SRD2_k127_5189133_15	1123267.JONN01000001_gene1365	1.1e-19	92.0	2A3CY@1|root,30RVE@2|Bacteria,1NNPQ@1224|Proteobacteria,2UJZN@28211|Alphaproteobacteria,2K7DT@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
SRD2_k127_5189133_11	314266.SKA58_14912	1.421e-40	158.0	COG0594@1|root,COG0594@2|Bacteria,1N6QY@1224|Proteobacteria,2UFAB@28211|Alphaproteobacteria,2K5Y4@204457|Sphingomonadales	204457|Sphingomonadales	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRD2_k127_5189133_14	1090320.KB900605_gene3217	4.147e-31	128.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2UFKH@28211|Alphaproteobacteria,2K6W4@204457|Sphingomonadales	204457|Sphingomonadales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRD2_k127_5189133_3	1123267.JONN01000001_gene1369	1.225e-198	634.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2TSTJ@28211|Alphaproteobacteria,2K1E1@204457|Sphingomonadales	204457|Sphingomonadales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
SRD2_k127_5189133_6	745310.G432_15400	2.36e-95	316.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2U5E5@28211|Alphaproteobacteria,2K0SN@204457|Sphingomonadales	204457|Sphingomonadales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
SRD2_k127_5189133_5	1123269.NX02_07160	1.018e-97	323.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2TTQZ@28211|Alphaproteobacteria,2K0C9@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_2,GST_N_3
SRD2_k127_5189133_8	317655.Sala_2020	1.265e-69	238.0	COG3837@1|root,COG3837@2|Bacteria,1R9WZ@1224|Proteobacteria,2U7QQ@28211|Alphaproteobacteria,2K4VJ@204457|Sphingomonadales	204457|Sphingomonadales	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD2_k127_5189133_2	1449076.JOOE01000004_gene240	3.54e-209	674.0	COG4206@1|root,COG4206@2|Bacteria,1QUUI@1224|Proteobacteria,2TW89@28211|Alphaproteobacteria,2K1UP@204457|Sphingomonadales	204457|Sphingomonadales	H	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug
SRD2_k127_5189133_4	1123267.JONN01000001_gene1374	1.067e-168	537.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2TT0J@28211|Alphaproteobacteria,2K0C3@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRD2_k127_5189133_1	1123267.JONN01000001_gene1375	3.508e-235	740.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K2DF@204457|Sphingomonadales	204457|Sphingomonadales	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRD2_k127_5189133_13	1007104.SUS17_1334	1.343e-31	133.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2UCM1@28211|Alphaproteobacteria,2K652@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Smr
SRD2_k127_5189133_7	1550073.JROH01000005_gene1655	3.63e-86	288.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2TS5S@28211|Alphaproteobacteria,2K0IG@204457|Sphingomonadales	204457|Sphingomonadales	M	membrane-bound lytic murein transglycosylase	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
SRD2_k127_520198_0	1123267.JONN01000001_gene386	4.278e-189	599.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2K0BI@204457|Sphingomonadales	204457|Sphingomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRD2_k127_520198_1	1123267.JONN01000001_gene385	3.898e-187	592.0	COG2733@1|root,COG2733@2|Bacteria,1MX3G@1224|Proteobacteria,2U15J@28211|Alphaproteobacteria,2K0FY@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
SRD2_k127_520198_2	1123269.NX02_01890	1.064e-10	64.0	2AAB5@1|root,30ZKU@2|Bacteria,1PMIY@1224|Proteobacteria,2V05S@28211|Alphaproteobacteria,2K9YA@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5207445_34	629773.AORY01000002_gene1728	1.261e-45	171.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2UC0F@28211|Alphaproteobacteria,2K5EC@204457|Sphingomonadales	204457|Sphingomonadales	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRD2_k127_5207445_32	1123267.JONN01000001_gene2280	2.735e-53	189.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2U93J@28211|Alphaproteobacteria,2K591@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA hydrolase	-	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
SRD2_k127_5207445_36	1123267.JONN01000001_gene2277	7.328e-41	158.0	COG5373@1|root,COG5373@2|Bacteria,1N7JV@1224|Proteobacteria,2TR7A@28211|Alphaproteobacteria,2K53N@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4167)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4167
SRD2_k127_5207445_24	1090319.KE386571_gene2888	4.881e-89	304.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2TZFK@28211|Alphaproteobacteria,2K12S@204457|Sphingomonadales	204457|Sphingomonadales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
SRD2_k127_5207445_8	392499.Swit_2530	2.706e-175	556.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2TQSV@28211|Alphaproteobacteria,2K1M6@204457|Sphingomonadales	204457|Sphingomonadales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRD2_k127_5207445_7	1219045.BV98_003787	3.191e-181	575.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2TSTH@28211|Alphaproteobacteria,2K101@204457|Sphingomonadales	204457|Sphingomonadales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRD2_k127_5207445_11	1123267.JONN01000001_gene2271	1.844e-165	549.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1MXFM@1224|Proteobacteria,2TWYV@28211|Alphaproteobacteria,2K14T@204457|Sphingomonadales	204457|Sphingomonadales	H	Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRD2_k127_5207445_3	1123267.JONN01000001_gene2271	3.102e-227	734.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1MXFM@1224|Proteobacteria,2TWYV@28211|Alphaproteobacteria,2K14T@204457|Sphingomonadales	204457|Sphingomonadales	H	Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRD2_k127_5207445_2	685778.AORL01000025_gene122	5.576e-248	782.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2TRZF@28211|Alphaproteobacteria,2K0CU@204457|Sphingomonadales	204457|Sphingomonadales	S	protease with the C-terminal PDZ	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
SRD2_k127_5207445_6	1123240.ATVO01000008_gene2479	1.132e-181	584.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TV11@28211|Alphaproteobacteria,2K0M0@204457|Sphingomonadales	204457|Sphingomonadales	J	Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRD2_k127_5207445_25	1242864.D187_008923	4.415e-87	298.0	COG0657@1|root,COG0657@2|Bacteria,1RGFY@1224|Proteobacteria	1224|Proteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRD2_k127_5207445_37	82654.Pse7367_2512	1.263e-37	157.0	COG0491@1|root,COG0491@2|Bacteria,1G455@1117|Cyanobacteria,1HDSU@1150|Oscillatoriales	1117|Cyanobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRD2_k127_5207445_33	392499.Swit_2122	1.146e-46	170.0	COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,2UBR4@28211|Alphaproteobacteria,2K583@204457|Sphingomonadales	204457|Sphingomonadales	P	Small Multidrug Resistance protein	-	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
SRD2_k127_5207445_31	13690.CP98_02188	2.768e-54	199.0	COG4291@1|root,COG4291@2|Bacteria,1RGUF@1224|Proteobacteria,2TRCQ@28211|Alphaproteobacteria,2K1VR@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1345
SRD2_k127_5207445_27	745310.G432_08300	1.109e-67	240.0	COG0697@1|root,COG0697@2|Bacteria,1RC7K@1224|Proteobacteria,2U0HX@28211|Alphaproteobacteria,2KDGS@204457|Sphingomonadales	204457|Sphingomonadales	EG	EamA-like transporter family	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
SRD2_k127_5207445_4	745310.G432_08305	4.089e-211	660.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2TQSI@28211|Alphaproteobacteria,2K1FA@204457|Sphingomonadales	204457|Sphingomonadales	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRD2_k127_5207445_17	1248917.ANFX01000011_gene167	3.669e-122	418.0	COG0457@1|root,COG0457@2|Bacteria,1N06S@1224|Proteobacteria,2TQVV@28211|Alphaproteobacteria,2K2KZ@204457|Sphingomonadales	204457|Sphingomonadales	S	MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
SRD2_k127_5207445_26	1123267.JONN01000002_gene287	3.74e-84	302.0	COG0758@1|root,COG0758@2|Bacteria,1R9P1@1224|Proteobacteria,2U30Q@28211|Alphaproteobacteria,2K3JF@204457|Sphingomonadales	204457|Sphingomonadales	LU	DNA mediated transformation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5207445_18	1123267.JONN01000001_gene2262	5.019e-114	376.0	COG1073@1|root,COG1073@2|Bacteria,1R67P@1224|Proteobacteria,2U3D5@28211|Alphaproteobacteria,2K2QV@204457|Sphingomonadales	204457|Sphingomonadales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRD2_k127_5207445_42	158500.BV97_03916	2.954e-12	72.0	2EGBE@1|root,33A39@2|Bacteria,1NHZG@1224|Proteobacteria,2UKX9@28211|Alphaproteobacteria,2K7TT@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5207445_40	1090320.KB900605_gene915	2.669e-19	90.0	COG4877@1|root,COG4877@2|Bacteria,1NJMT@1224|Proteobacteria,2UK5B@28211|Alphaproteobacteria,2K6XY@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HicB
SRD2_k127_5207445_15	1449076.JOOE01000004_gene453	5.55e-137	441.0	COG0330@1|root,COG0330@2|Bacteria,1P8ZI@1224|Proteobacteria,2TTBE@28211|Alphaproteobacteria,2JZUP@204457|Sphingomonadales	204457|Sphingomonadales	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRD2_k127_5207445_22	1123267.JONN01000001_gene2258	1.131e-104	349.0	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,2TU8K@28211|Alphaproteobacteria,2K0JU@204457|Sphingomonadales	204457|Sphingomonadales	E	Asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
SRD2_k127_5207445_13	1123267.JONN01000001_gene2247	3.464e-156	501.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2TS5I@28211|Alphaproteobacteria,2K1NQ@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
SRD2_k127_5207445_28	1123267.JONN01000001_gene2249	3.487e-65	235.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2U9H4@28211|Alphaproteobacteria,2K4U7@204457|Sphingomonadales	204457|Sphingomonadales	J	endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRD2_k127_5207445_20	1123267.JONN01000001_gene2250	8.154e-106	349.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,2TR5S@28211|Alphaproteobacteria,2K1R4@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.276	ko:K05886	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
SRD2_k127_5207445_39	745310.G432_12055	2.331e-19	90.0	2DMKE@1|root,32S6E@2|Bacteria,1NH3D@1224|Proteobacteria,2UHAS@28211|Alphaproteobacteria,2K72S@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3572
SRD2_k127_5207445_35	1123267.JONN01000001_gene2253	2.007e-45	169.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2U745@28211|Alphaproteobacteria,2K53C@204457|Sphingomonadales	204457|Sphingomonadales	T	response regulator	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRD2_k127_5207445_38	1192759.AKIB01000005_gene172	6.282e-24	102.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2UF4D@28211|Alphaproteobacteria,2K6VC@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRD2_k127_5207445_1	1123267.JONN01000001_gene2256	1.298e-257	803.0	COG1793@1|root,COG1793@2|Bacteria,1MV3S@1224|Proteobacteria,2TRQ9@28211|Alphaproteobacteria,2K08Z@204457|Sphingomonadales	204457|Sphingomonadales	L	ATP-dependent DNA ligase	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRD2_k127_5207445_10	1112216.JH594425_gene1603	7.858e-173	552.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,2K0Q2@204457|Sphingomonadales	204457|Sphingomonadales	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRD2_k127_5207445_9	1123269.NX02_19010	2.803e-174	565.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,2TS7R@28211|Alphaproteobacteria,2K0U5@204457|Sphingomonadales	204457|Sphingomonadales	E	peptidase S10 serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
SRD2_k127_5207445_23	1123267.JONN01000001_gene2246	1.955e-104	346.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,2JZZ2@204457|Sphingomonadales	204457|Sphingomonadales	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRD2_k127_5207445_21	1123267.JONN01000001_gene2245	2.841e-105	344.0	COG0349@1|root,COG0349@2|Bacteria,1MWFD@1224|Proteobacteria,2TQXS@28211|Alphaproteobacteria,2K0FG@204457|Sphingomonadales	204457|Sphingomonadales	L	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1
SRD2_k127_5207445_29	1123267.JONN01000001_gene2244	1.495e-63	226.0	COG5375@1|root,COG5375@2|Bacteria,1NMV8@1224|Proteobacteria,2VCS4@28211|Alphaproteobacteria,2K34V@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein conserved in bacteria	-	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
SRD2_k127_5207445_30	1123267.JONN01000001_gene2243	4.81e-61	220.0	COG1934@1|root,COG1934@2|Bacteria,1MXGA@1224|Proteobacteria,2U6DD@28211|Alphaproteobacteria,2K3YP@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
SRD2_k127_5207445_16	1123267.JONN01000001_gene2242	1.458e-133	430.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2TR7F@28211|Alphaproteobacteria,2K0YX@204457|Sphingomonadales	204457|Sphingomonadales	S	ABC-type (Unclassified) transport system, ATPase component	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
SRD2_k127_5207445_12	1090320.KB900605_gene847	4.01e-158	512.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2TS41@28211|Alphaproteobacteria,2K182@204457|Sphingomonadales	204457|Sphingomonadales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
SRD2_k127_5207445_19	1123267.JONN01000001_gene2240	7.613e-109	358.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2U1MH@28211|Alphaproteobacteria,2K0EG@204457|Sphingomonadales	204457|Sphingomonadales	L	endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRD2_k127_5207445_0	555217.Zmob_1552	0.0	1200.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2TRBK@28211|Alphaproteobacteria,2K0E4@204457|Sphingomonadales	204457|Sphingomonadales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRD2_k127_5207445_14	1123267.JONN01000001_gene2234	3.659e-147	474.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,2TQRD@28211|Alphaproteobacteria,2K0WV@204457|Sphingomonadales	204457|Sphingomonadales	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRD2_k127_5207445_5	1123267.JONN01000001_gene2229	6.461e-203	635.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2TSRZ@28211|Alphaproteobacteria,2K052@204457|Sphingomonadales	204457|Sphingomonadales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRD2_k127_5285265_9	1112212.JH584235_gene1109	6.038e-84	286.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,2K1UV@204457|Sphingomonadales	204457|Sphingomonadales	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRD2_k127_5285265_0	1123267.JONN01000001_gene481	7.369e-183	580.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2K130@204457|Sphingomonadales	204457|Sphingomonadales	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
SRD2_k127_5285265_5	452662.SJA_C1-15210	1.648e-126	410.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2TQY8@28211|Alphaproteobacteria,2K00M@204457|Sphingomonadales	204457|Sphingomonadales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
SRD2_k127_5285265_7	1449076.JOOE01000001_gene2717	1e-100	339.0	COG3710@1|root,COG3710@2|Bacteria,1PE98@1224|Proteobacteria,2VD0F@28211|Alphaproteobacteria,2K3KN@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRD2_k127_5285265_11	685778.AORL01000021_gene921	7.292e-68	236.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,2TVKC@28211|Alphaproteobacteria,2K4M1@204457|Sphingomonadales	204457|Sphingomonadales	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD2_k127_5285265_16	685778.AORL01000021_gene922	3.253e-33	141.0	2ES5B@1|root,33JQ4@2|Bacteria,1NHPR@1224|Proteobacteria,2UN83@28211|Alphaproteobacteria,2K67H@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRD2_k127_5285265_4	685778.AORL01000021_gene923	1.219e-132	443.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2TT0E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRD2_k127_5285265_13	685778.AORL01000021_gene924	4.304e-46	176.0	2FDTI@1|root,345U8@2|Bacteria,1NJ6F@1224|Proteobacteria,2V4SS@28211|Alphaproteobacteria,2K6Q3@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
SRD2_k127_5285265_2	1122612.AUBA01000003_gene1661	5.683e-154	503.0	28JQB@1|root,2Z9G8@2|Bacteria,1QCH9@1224|Proteobacteria,2U822@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5285265_17	1112212.JH584235_gene1551	2.241e-14	86.0	2EJQP@1|root,33DFH@2|Bacteria,1NI6C@1224|Proteobacteria,2UMF9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HIPIP
SRD2_k127_5285265_3	1123267.JONN01000001_gene1662	1.866e-141	451.0	COG0745@1|root,COG0745@2|Bacteria,1MWVI@1224|Proteobacteria,2TRSP@28211|Alphaproteobacteria,2K0S8@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ctrA	-	-	ko:K13584	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD2_k127_5285265_8	1123267.JONN01000001_gene1661	6.033e-98	326.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,2TSCG@28211|Alphaproteobacteria,2K0XZ@204457|Sphingomonadales	204457|Sphingomonadales	J	Pseudouridine synthase	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
SRD2_k127_5285265_14	194867.ALBQ01000032_gene941	1.439e-42	162.0	COG0216@1|root,COG0216@2|Bacteria,1R348@1224|Proteobacteria,2TZXT@28211|Alphaproteobacteria,2KEW4@204457|Sphingomonadales	204457|Sphingomonadales	J	chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SRD2_k127_5285265_10	1123267.JONN01000001_gene1576	1.391e-70	246.0	COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,2U595@28211|Alphaproteobacteria,2K4NG@204457|Sphingomonadales	204457|Sphingomonadales	T	GAF domain-containing protein	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
SRD2_k127_5285265_12	1123267.JONN01000001_gene1574	5.567e-48	194.0	COG0589@1|root,COG0589@2|Bacteria,1R9XB@1224|Proteobacteria,2U59E@28211|Alphaproteobacteria,2K49I@204457|Sphingomonadales	204457|Sphingomonadales	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRD2_k127_5285265_1	13690.CP98_00698	4.55e-174	557.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2TRXM@28211|Alphaproteobacteria,2K0EK@204457|Sphingomonadales	204457|Sphingomonadales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRD2_k127_5285265_15	161528.ED21_27563	1.57e-41	158.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2U93J@28211|Alphaproteobacteria,2K4GY@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA thioester hydrolase	-	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
SRD2_k127_5285265_6	46429.BV95_00025	1.57e-114	374.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TR8H@28211|Alphaproteobacteria,2JZWH@204457|Sphingomonadales	204457|Sphingomonadales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRD2_k127_5314887_12	745310.G432_02030	1.106e-82	278.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2TUHX@28211|Alphaproteobacteria,2K07X@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome c1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
SRD2_k127_5314887_3	1174684.EBMC1_10224	4.053e-219	693.0	COG2234@1|root,COG2234@2|Bacteria,1MWQ0@1224|Proteobacteria,2U1HX@28211|Alphaproteobacteria,2JZUX@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRD2_k127_5314887_17	1219049.SP5_018_00920	4.889e-21	98.0	28RMB@1|root,2ZE02@2|Bacteria,1P04A@1224|Proteobacteria,2UV0Q@28211|Alphaproteobacteria,2K50J@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5314887_13	1112216.JH594425_gene3607	1.649e-59	211.0	COG2030@1|root,COG2030@2|Bacteria,1RIBV@1224|Proteobacteria,2U9QR@28211|Alphaproteobacteria,2K4JQ@204457|Sphingomonadales	204457|Sphingomonadales	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRD2_k127_5314887_4	1112212.JH584235_gene1438	2.154e-216	683.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,2K04M@204457|Sphingomonadales	204457|Sphingomonadales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16,TPR_19,TPR_8
SRD2_k127_5314887_0	1123267.JONN01000001_gene2395	5.268e-280	885.0	COG1629@1|root,COG1629@2|Bacteria,1QUTW@1224|Proteobacteria,2TW7F@28211|Alphaproteobacteria,2KECH@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRD2_k127_5314887_16	1123267.JONN01000001_gene1432	4.862e-32	133.0	COG0671@1|root,COG0671@2|Bacteria,1RDK3@1224|Proteobacteria,2U7BJ@28211|Alphaproteobacteria,2K70Y@204457|Sphingomonadales	204457|Sphingomonadales	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRD2_k127_5314887_5	1090320.KB900605_gene626	1.597e-186	588.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2TRAD@28211|Alphaproteobacteria,2K213@204457|Sphingomonadales	204457|Sphingomonadales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRD2_k127_5314887_15	1089551.KE386572_gene640	2.941e-48	179.0	COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,2UBZM@28211|Alphaproteobacteria,4BQVN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	nsrR	-	-	ko:K13771,ko:K13772	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
SRD2_k127_5314887_9	1123267.JONN01000001_gene553	2.594e-90	300.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,Peptidase_C39_2,Rhomboid,TPR_16,TPR_19,TPR_8
SRD2_k127_5314887_2	291985.CCSI01000001_gene2264	9.771e-266	842.0	COG1913@1|root,COG1913@2|Bacteria,1MY52@1224|Proteobacteria,2TUDY@28211|Alphaproteobacteria,2K1Q2@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117
SRD2_k127_5314887_7	1057002.KB905370_gene2611	2.578e-113	387.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_8
SRD2_k127_5314887_10	685035.ADAE01000018_gene652	1.127e-86	289.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2TT6Q@28211|Alphaproteobacteria,2K0UK@204457|Sphingomonadales	204457|Sphingomonadales	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRD2_k127_5314887_11	1346791.M529_21225	4.094e-84	284.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2U5P0@28211|Alphaproteobacteria,2K122@204457|Sphingomonadales	204457|Sphingomonadales	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRD2_k127_5314887_14	1123267.JONN01000001_gene1457	4.21e-49	184.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,2U5RA@28211|Alphaproteobacteria,2JZWN@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
SRD2_k127_5314887_8	1123267.JONN01000001_gene1456	1.92e-100	336.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,2U5RA@28211|Alphaproteobacteria,2JZWN@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
SRD2_k127_5314887_6	1123267.JONN01000001_gene1455	2.692e-164	521.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2TS2N@28211|Alphaproteobacteria,2K1RK@204457|Sphingomonadales	204457|Sphingomonadales	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
SRD2_k127_5314887_1	1123267.JONN01000001_gene1454	6.189e-272	854.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2TQKJ@28211|Alphaproteobacteria,2K16M@204457|Sphingomonadales	204457|Sphingomonadales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
SRD2_k127_5385497_4	1123267.JONN01000001_gene1052	4.873e-63	222.0	COG0642@1|root,COG2205@2|Bacteria,1MVY8@1224|Proteobacteria,2TS5B@28211|Alphaproteobacteria,2K08R@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7
SRD2_k127_5385497_5	685035.ADAE01000018_gene506	1.797e-31	128.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2UBQ9@28211|Alphaproteobacteria,2K5A7@204457|Sphingomonadales	204457|Sphingomonadales	S	ATPase or kinase	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRD2_k127_5385497_1	1123267.JONN01000001_gene1054	2.287e-161	517.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2TSJD@28211|Alphaproteobacteria,2K04R@204457|Sphingomonadales	204457|Sphingomonadales	S	Phosphotransferase	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
SRD2_k127_5385497_3	1123267.JONN01000001_gene1055	8.131e-117	387.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2TU2V@28211|Alphaproteobacteria,2K1HH@204457|Sphingomonadales	204457|Sphingomonadales	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3,NTP_transferase
SRD2_k127_5385497_0	1123267.JONN01000001_gene1056	0.0	1021.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2TS74@28211|Alphaproteobacteria,2K06P@204457|Sphingomonadales	204457|Sphingomonadales	L	helicase	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
SRD2_k127_5385497_2	1123267.JONN01000001_gene1058	4.907e-139	455.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2TQJZ@28211|Alphaproteobacteria,2K07I@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRD2_k127_551935_2	240015.ACP_0672	9.833e-19	93.0	COG2010@1|root,COG2010@2|Bacteria,3Y4X7@57723|Acidobacteria,2JJFH@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRD2_k127_551935_1	1449076.JOOE01000001_gene2321	3.66e-24	109.0	2AKT3@1|root,31BK4@2|Bacteria,1P4RX@1224|Proteobacteria,2UXC3@28211|Alphaproteobacteria,2K5G1@204457|Sphingomonadales	204457|Sphingomonadales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
SRD2_k127_551935_0	1123267.JONN01000001_gene570	0.0	1218.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2TS2B@28211|Alphaproteobacteria,2K04E@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRD2_k127_551935_3	1030157.AFMP01000013_gene3328	7.2e-17	84.0	COG3794@1|root,COG3794@2|Bacteria,1N2CZ@1224|Proteobacteria,2UEDD@28211|Alphaproteobacteria,2K66I@204457|Sphingomonadales	204457|Sphingomonadales	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRD2_k127_5523857_12	1449076.JOOE01000002_gene948	1.905e-70	246.0	COG2755@1|root,COG2755@2|Bacteria,1RE9P@1224|Proteobacteria,2UJZG@28211|Alphaproteobacteria,2K30X@204457|Sphingomonadales	204457|Sphingomonadales	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRD2_k127_5523857_10	1248760.ANFZ01000015_gene1664	3.868e-78	269.0	COG1482@1|root,COG1482@2|Bacteria,1P6JR@1224|Proteobacteria,2U30V@28211|Alphaproteobacteria,2K0Y1@204457|Sphingomonadales	204457|Sphingomonadales	G	isomerase	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRD2_k127_5523857_6	1081640.AGFU01000042_gene3152	9.018e-102	340.0	COG1940@1|root,COG1940@2|Bacteria,1R7YN@1224|Proteobacteria,2TUWX@28211|Alphaproteobacteria,2K1T7@204457|Sphingomonadales	204457|Sphingomonadales	GK	Transcriptional regulator sugar kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
SRD2_k127_5523857_5	1335760.ASTG01000025_gene1971	2.898e-118	388.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2TR5J@28211|Alphaproteobacteria,2K0RM@204457|Sphingomonadales	204457|Sphingomonadales	L	exodeoxyribonuclease III	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRD2_k127_5523857_3	1346791.M529_01490	2.528e-178	565.0	COG0498@1|root,COG0498@2|Bacteria,1R7X1@1224|Proteobacteria,2TUR3@28211|Alphaproteobacteria,2K0P7@204457|Sphingomonadales	204457|Sphingomonadales	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD2_k127_5523857_7	443598.AUFA01000003_gene2026	4.208e-95	319.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TR65@28211|Alphaproteobacteria,3JTI5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	cation efflux	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRD2_k127_5523857_18	1219045.BV98_001947	2.806e-18	87.0	29B0T@1|root,2ZXZQ@2|Bacteria,1ND25@1224|Proteobacteria,2UJ2J@28211|Alphaproteobacteria,2K6SU@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5523857_17	1123267.JONN01000001_gene689	1.138e-20	97.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
SRD2_k127_5523857_11	1123267.JONN01000001_gene1114	1.693e-74	258.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,2U6CN@28211|Alphaproteobacteria,2K2DP@204457|Sphingomonadales	204457|Sphingomonadales	KT	Phage shock protein A	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRD2_k127_5523857_19	1219035.NT2_05_02150	5.527e-05	51.0	2AMI2@1|root,31CDP@2|Bacteria,1P2BA@1224|Proteobacteria,2UVHW@28211|Alphaproteobacteria,2K86C@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5523857_14	1123267.JONN01000001_gene685	5.228e-38	144.0	2CC0C@1|root,32ZJ1@2|Bacteria,1R3EF@1224|Proteobacteria,2U01N@28211|Alphaproteobacteria,2KEWT@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3297)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3297
SRD2_k127_5523857_1	1123267.JONN01000001_gene683	4.736e-212	668.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TSEI@28211|Alphaproteobacteria,2K13V@204457|Sphingomonadales	204457|Sphingomonadales	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	E1_dh,OxoDH_E1alpha_N
SRD2_k127_5523857_2	1123267.JONN01000001_gene682	1.4e-189	595.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRFK@28211|Alphaproteobacteria,2K02S@204457|Sphingomonadales	204457|Sphingomonadales	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	bkdA2	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRD2_k127_5523857_4	1346791.M529_00710	5.747e-141	460.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2TS31@28211|Alphaproteobacteria,2K1MM@204457|Sphingomonadales	204457|Sphingomonadales	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bkdB	-	2.3.1.168	ko:K09699	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R02662,R03174,R04097,R10998	RC00004,RC02727,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRD2_k127_5523857_15	1123267.JONN01000001_gene680	4.986e-36	144.0	2DXAI@1|root,3444M@2|Bacteria,1P0TN@1224|Proteobacteria,2UVMP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SRD2_k127_5523857_16	649831.L083_3552	7.136e-27	111.0	2DD18@1|root,2ZG4B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5523857_9	935848.JAEN01000013_gene4122	1.186e-79	269.0	COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,2U8Z1@28211|Alphaproteobacteria,2PWT8@265|Paracoccus	28211|Alphaproteobacteria	I	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity	azoR	-	-	ko:K01118	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_2
SRD2_k127_5523857_13	1123267.JONN01000001_gene677	1.144e-53	192.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6N@1224|Proteobacteria,2UC19@28211|Alphaproteobacteria,2K6D3@204457|Sphingomonadales	204457|Sphingomonadales	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRD2_k127_5523857_8	1123267.JONN01000001_gene1074	3.251e-81	284.0	COG3555@1|root,COG3555@2|Bacteria,1MW3M@1224|Proteobacteria,2U5YV@28211|Alphaproteobacteria,2K07E@204457|Sphingomonadales	204457|Sphingomonadales	O	Aspartyl/Asparaginyl beta-hydroxylase	-	-	-	ko:K12979	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Asp_Arg_Hydrox
SRD2_k127_5523857_0	1123267.JONN01000001_gene676	0.0	1131.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2TSZ9@28211|Alphaproteobacteria,2K18V@204457|Sphingomonadales	204457|Sphingomonadales	C	Transketolase, thiamine diphosphate binding domain	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N
SRD2_k127_5566299_2	1123267.JONN01000002_gene118	1.377e-95	329.0	COG3147@1|root,COG5010@1|root,COG3147@2|Bacteria,COG5010@2|Bacteria,1RK9P@1224|Proteobacteria,2U5CI@28211|Alphaproteobacteria,2K119@204457|Sphingomonadales	204457|Sphingomonadales	U	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_16,TPR_19,TPR_4
SRD2_k127_5566299_0	1123267.JONN01000002_gene119	1.458e-118	387.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2TRHP@28211|Alphaproteobacteria,2K0IH@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRD2_k127_5566299_3	1123267.JONN01000002_gene120	6.735e-67	234.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2U98Y@28211|Alphaproteobacteria,2K4GA@204457|Sphingomonadales	204457|Sphingomonadales	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRD2_k127_5566299_1	1112214.AHIS01000095_gene800	3.189e-117	384.0	COG2267@1|root,COG2267@2|Bacteria,1MVDA@1224|Proteobacteria,2TUDQ@28211|Alphaproteobacteria,2K1MR@204457|Sphingomonadales	204457|Sphingomonadales	I	Protein of unknown function (DUF3089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3089
SRD2_k127_5574925_14	1537715.JQFJ01000002_gene1142	3.904e-52	201.0	COG2813@1|root,COG2813@2|Bacteria,1RHAE@1224|Proteobacteria,2U5V5@28211|Alphaproteobacteria,2K42K@204457|Sphingomonadales	204457|Sphingomonadales	J	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
SRD2_k127_5574925_15	1549858.MC45_05600	4.101e-45	169.0	2ERK7@1|root,33J5Q@2|Bacteria,1NRZ4@1224|Proteobacteria,2UQEM@28211|Alphaproteobacteria,2K44W@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1453)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1453
SRD2_k127_5574925_0	1123267.JONN01000001_gene1436	1.915e-283	880.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2TSFF@28211|Alphaproteobacteria,2K1GP@204457|Sphingomonadales	204457|Sphingomonadales	E	Glycine dehydrogenase (aminomethyl-transferring)	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRD2_k127_5574925_2	1123267.JONN01000001_gene1437	2.163e-219	690.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2TR6C@28211|Alphaproteobacteria,2K0IW@204457|Sphingomonadales	204457|Sphingomonadales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRD2_k127_5574925_9	1123267.JONN01000001_gene1438	4.43e-97	323.0	COG4106@1|root,COG4106@2|Bacteria,1R04W@1224|Proteobacteria,2U5VR@28211|Alphaproteobacteria,2K298@204457|Sphingomonadales	204457|Sphingomonadales	S	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRD2_k127_5574925_13	1123267.JONN01000001_gene1439	4.299e-59	207.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2U9BY@28211|Alphaproteobacteria,2K5E0@204457|Sphingomonadales	204457|Sphingomonadales	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRD2_k127_5574925_5	1123267.JONN01000001_gene1440	2.526e-152	496.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2TRN4@28211|Alphaproteobacteria,2K1GI@204457|Sphingomonadales	204457|Sphingomonadales	E	Glycine cleavage system T protein	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRD2_k127_5574925_11	1123267.JONN01000001_gene1443	6.484e-62	220.0	2B5IK@1|root,31YDD@2|Bacteria,1RAZF@1224|Proteobacteria,2U6F0@28211|Alphaproteobacteria,2K43H@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5574925_4	1123267.JONN01000001_gene1444	1.409e-154	496.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2TRNR@28211|Alphaproteobacteria,2K1ES@204457|Sphingomonadales	204457|Sphingomonadales	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRD2_k127_5574925_10	452662.SJA_C1-28190	2.186e-69	238.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2U7C4@28211|Alphaproteobacteria,2K3YC@204457|Sphingomonadales	204457|Sphingomonadales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
SRD2_k127_5574925_8	1123267.JONN01000001_gene1446	2.674e-117	387.0	COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria,2TRM2@28211|Alphaproteobacteria,2JZYS@204457|Sphingomonadales	204457|Sphingomonadales	E	Oxidoreductase	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
SRD2_k127_5574925_16	1207055.C100_05075	2.018e-41	158.0	COG4960@1|root,COG4960@2|Bacteria,1RAYG@1224|Proteobacteria,2UJT9@28211|Alphaproteobacteria,2K6EK@204457|Sphingomonadales	204457|Sphingomonadales	OU	peptidase	cpaA	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
SRD2_k127_5574925_6	1123267.JONN01000001_gene1447	1.837e-139	451.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,2TTPE@28211|Alphaproteobacteria,2K08W@204457|Sphingomonadales	204457|Sphingomonadales	U	Pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
SRD2_k127_5574925_3	1123267.JONN01000001_gene1448	1.26e-157	512.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,2TRNN@28211|Alphaproteobacteria,2K0ZQ@204457|Sphingomonadales	204457|Sphingomonadales	U	Belongs to the GSP D family	cpaC	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
SRD2_k127_5574925_12	1123267.JONN01000001_gene1449	2.1e-61	225.0	COG5461@1|root,COG5461@2|Bacteria,1REYP@1224|Proteobacteria,2U8J3@28211|Alphaproteobacteria,2K5AY@204457|Sphingomonadales	204457|Sphingomonadales	N	Pilus assembly protein CpaD	cpaD	-	-	ko:K02281	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Pilus_CpaD
SRD2_k127_5574925_1	1123267.JONN01000001_gene1450	6.534e-233	724.0	COG2204@1|root,COG4963@1|root,COG2204@2|Bacteria,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2TUDS@28211|Alphaproteobacteria,2K0BT@204457|Sphingomonadales	204457|Sphingomonadales	TU	Flp pilus assembly protein, ATPase CpaE	cpaE	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	CbiA,ParA
SRD2_k127_5574925_7	1123267.JONN01000001_gene1451	7.84e-126	409.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,2TRBI@28211|Alphaproteobacteria,2K0B5@204457|Sphingomonadales	204457|Sphingomonadales	U	pilus assembly protein TadB	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRD2_k127_5605124_6	1123267.JONN01000001_gene386	3.965e-129	418.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2K0BI@204457|Sphingomonadales	204457|Sphingomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRD2_k127_5605124_3	1123267.JONN01000001_gene385	6.153e-192	606.0	COG2733@1|root,COG2733@2|Bacteria,1MX3G@1224|Proteobacteria,2U15J@28211|Alphaproteobacteria,2K0FY@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
SRD2_k127_5605124_21	497964.CfE428DRAFT_4663	1.796e-15	90.0	COG0454@1|root,COG0456@2|Bacteria,46W5V@74201|Verrucomicrobia	74201|Verrucomicrobia	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD2_k127_5605124_1	1123267.JONN01000001_gene377	2.157e-229	715.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria,2K1H1@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRD2_k127_5605124_14	1123267.JONN01000001_gene378	9.562e-56	196.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2U982@28211|Alphaproteobacteria,2K5BT@204457|Sphingomonadales	204457|Sphingomonadales	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRD2_k127_5605124_17	1123267.JONN01000001_gene379	5.575e-36	145.0	COG5490@1|root,COG5490@2|Bacteria,1N3RI@1224|Proteobacteria,2UDTZ@28211|Alphaproteobacteria,2K476@204457|Sphingomonadales	204457|Sphingomonadales	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
SRD2_k127_5605124_10	745310.G432_11670	8.135e-82	278.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2TSCQ@28211|Alphaproteobacteria,2K16A@204457|Sphingomonadales	204457|Sphingomonadales	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRD2_k127_5605124_9	1123267.JONN01000001_gene381	3.983e-87	293.0	COG5387@1|root,COG5387@2|Bacteria,1Q3B5@1224|Proteobacteria,2TVK1@28211|Alphaproteobacteria,2K1FD@204457|Sphingomonadales	204457|Sphingomonadales	O	Chaperone required for the assembly of the mitochondrial F1-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ATP12
SRD2_k127_5605124_11	1123267.JONN01000001_gene383	1.275e-78	270.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2U703@28211|Alphaproteobacteria,2K3XQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRD2_k127_5605124_4	1123267.JONN01000001_gene384	2.995e-157	503.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2TTQC@28211|Alphaproteobacteria,2K1YR@204457|Sphingomonadales	204457|Sphingomonadales	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
SRD2_k127_5605124_16	1123267.JONN01000001_gene376	6.023e-38	147.0	2E4C3@1|root,32Z7N@2|Bacteria,1N1SM@1224|Proteobacteria,2UEBN@28211|Alphaproteobacteria,2K667@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5605124_12	1123267.JONN01000001_gene375	1.764e-74	257.0	2E21J@1|root,32X9B@2|Bacteria,1NEYU@1224|Proteobacteria,2UJ33@28211|Alphaproteobacteria,2K6I0@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4893)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4893
SRD2_k127_5605124_8	1123267.JONN01000001_gene374	3.46e-99	332.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,2TV8D@28211|Alphaproteobacteria,2K1SV@204457|Sphingomonadales	204457|Sphingomonadales	S	RarD protein	-	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
SRD2_k127_5605124_20	317655.Sala_1429	6.194e-22	97.0	2EIB4@1|root,33C2I@2|Bacteria,1NCTY@1224|Proteobacteria,2UHUB@28211|Alphaproteobacteria,2K6ZK@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5605124_15	1121015.N789_11895	3.432e-48	182.0	COG4430@1|root,COG4430@2|Bacteria,1RG2R@1224|Proteobacteria,1T0AD@1236|Gammaproteobacteria,1X6JK@135614|Xanthomonadales	135614|Xanthomonadales	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
SRD2_k127_5605124_19	1320556.AVBP01000009_gene2469	1.709e-27	117.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	yrkN	-	2.3.1.82	ko:K03826,ko:K03827,ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRD2_k127_5605124_0	1123267.JONN01000001_gene372	1.961e-273	851.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TR7S@28211|Alphaproteobacteria,2K0U9@204457|Sphingomonadales	204457|Sphingomonadales	I	poly(R)-hydroxyalkanoic acid synthase	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
SRD2_k127_5605124_5	1123267.JONN01000001_gene1962	1.126e-143	468.0	COG1680@1|root,COG1680@2|Bacteria,1RB35@1224|Proteobacteria,2U2A3@28211|Alphaproteobacteria,2K36P@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRD2_k127_5605124_18	1267533.KB906741_gene652	2.352e-30	129.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	ysfE	-	2.7.1.49,2.7.4.7,4.2.1.96,4.4.1.5	ko:K00941,ko:K01724,ko:K01759,ko:K07032,ko:K08234	ko00620,ko00730,ko00790,ko01100,map00620,map00730,map00790,map01100	M00127	R02530,R03471,R04509,R04734	RC00002,RC00004,RC00017,RC00740,RC01208	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
SRD2_k127_5605124_2	1123267.JONN01000001_gene2476	3.768e-207	648.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2TRE3@28211|Alphaproteobacteria,2K0GY@204457|Sphingomonadales	204457|Sphingomonadales	E	Aminotransferase	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRD2_k127_5605124_13	194867.ALBQ01000013_gene804	2.097e-58	212.0	2C130@1|root,32R80@2|Bacteria,1RDSY@1224|Proteobacteria,2U84Y@28211|Alphaproteobacteria,2KEWC@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
SRD2_k127_5605124_7	378806.STAUR_0176	1.303e-107	356.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,438TR@68525|delta/epsilon subdivisions,2X9FE@28221|Deltaproteobacteria,2YXRD@29|Myxococcales	28221|Deltaproteobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRD2_k127_5659837_17	1122612.AUBA01000003_gene1661	1.782e-53	192.0	28JQB@1|root,2Z9G8@2|Bacteria,1QCH9@1224|Proteobacteria,2U822@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5659837_22	1112212.JH584235_gene1551	2.946e-24	106.0	2EJQP@1|root,33DFH@2|Bacteria,1NI6C@1224|Proteobacteria,2UMF9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HIPIP
SRD2_k127_5659837_27	391038.Bphy_0349	0.0001228	47.0	2FKU8@1|root,34CEN@2|Bacteria,1NAVZ@1224|Proteobacteria,2W5RW@28216|Betaproteobacteria,1KADB@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5659837_13	509190.Cseg_2282	1.094e-73	255.0	COG1622@1|root,COG1622@2|Bacteria,1NZNI@1224|Proteobacteria,2U284@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
SRD2_k127_5659837_2	509190.Cseg_2281	5.554e-257	803.0	COG0843@1|root,COG0843@2|Bacteria,1R57U@1224|Proteobacteria,2U068@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRD2_k127_5659837_14	509190.Cseg_2280	1.025e-62	227.0	COG2863@1|root,COG2863@2|Bacteria,1PG12@1224|Proteobacteria,2V88Z@28211|Alphaproteobacteria,2KJGI@204458|Caulobacterales	204458|Caulobacterales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5659837_25	1410668.JNKC01000016_gene993	1.811e-07	53.0	2DES4@1|root,2ZP1M@2|Bacteria,1W3CF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5659837_26	392499.Swit_1959	2.436e-06	52.0	28M8G@1|root,2ZAMM@2|Bacteria,1MVBT@1224|Proteobacteria,2TTGC@28211|Alphaproteobacteria,2K48T@204457|Sphingomonadales	204457|Sphingomonadales	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
SRD2_k127_5659837_21	392499.Swit_3181	9.107e-25	111.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282,ko:K07782,ko:K19135	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko02035,ko02044,ko02048,ko03000	-	-	-	Cas_NE0113,GerE,Response_reg,TPR_16
SRD2_k127_5659837_24	1379701.JPJC01000161_gene951	1.952e-20	98.0	2EP5S@1|root,33GSG@2|Bacteria,1NI0K@1224|Proteobacteria,2UK2B@28211|Alphaproteobacteria,2K7KA@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5659837_9	392499.Swit_2426	2.05e-93	320.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2TUG7@28211|Alphaproteobacteria,2K163@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRD2_k127_5659837_10	1123267.JONN01000001_gene1826	9.729e-86	291.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2TVJ7@28211|Alphaproteobacteria,2K0I0@204457|Sphingomonadales	204457|Sphingomonadales	L	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRD2_k127_5659837_20	1411123.JQNH01000001_gene264	9.395e-30	123.0	COG3278@1|root,COG3278@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
SRD2_k127_5659837_7	1123267.JONN01000001_gene1850	1.08e-119	387.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2TSR6@28211|Alphaproteobacteria,2K0PN@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
SRD2_k127_5659837_5	1545915.JROG01000009_gene2742	2.162e-133	440.0	COG4452@1|root,COG4452@2|Bacteria,1MVVR@1224|Proteobacteria,2TVJ2@28211|Alphaproteobacteria,2K3GA@204457|Sphingomonadales	204457|Sphingomonadales	V	Inner membrane protein CreD	-	-	-	-	-	-	-	-	-	-	-	-	CreD
SRD2_k127_5659837_6	1123267.JONN01000001_gene1787	5.99e-129	429.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2TR90@28211|Alphaproteobacteria,2K00V@204457|Sphingomonadales	204457|Sphingomonadales	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRD2_k127_5659837_11	745310.G432_02635	3.578e-78	270.0	COG3474@1|root,COG3474@2|Bacteria,1RIDN@1224|Proteobacteria,2U142@28211|Alphaproteobacteria,2K42S@204457|Sphingomonadales	204457|Sphingomonadales	C	cytochrome C	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
SRD2_k127_5659837_8	1123267.JONN01000001_gene1791	1.253e-109	367.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2TQVX@28211|Alphaproteobacteria,2K0ZZ@204457|Sphingomonadales	204457|Sphingomonadales	L	glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
SRD2_k127_5659837_15	1123267.JONN01000001_gene1792	2.034e-58	218.0	COG5389@1|root,COG5389@2|Bacteria,1N82D@1224|Proteobacteria,2UFA9@28211|Alphaproteobacteria,2K4U1@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRD2_k127_5659837_16	1123267.JONN01000001_gene1793	1.392e-56	206.0	COG1651@1|root,COG1651@2|Bacteria,1RFF4@1224|Proteobacteria,2U5BN@28211|Alphaproteobacteria,2KCZI@204457|Sphingomonadales	204457|Sphingomonadales	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRD2_k127_5659837_18	1331060.RLDS_14085	3.394e-48	183.0	COG1651@1|root,COG1651@2|Bacteria,1RFF4@1224|Proteobacteria,2U5BN@28211|Alphaproteobacteria,2KCZI@204457|Sphingomonadales	204457|Sphingomonadales	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRD2_k127_5659837_0	1123267.JONN01000001_gene1794	0.0	1073.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2TRQG@28211|Alphaproteobacteria,2K02F@204457|Sphingomonadales	204457|Sphingomonadales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N
SRD2_k127_5659837_3	1123267.JONN01000001_gene1795	3.028e-222	708.0	COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,2TVX5@28211|Alphaproteobacteria,2KED5@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	ko:K16090	-	-	-	-	ko00000,ko02000	1.B.14.1.11	-	-	Plug,TonB_dep_Rec
SRD2_k127_5659837_12	1112212.JH584235_gene1801	6.16e-76	282.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2TSAR@28211|Alphaproteobacteria,2K0Y7@204457|Sphingomonadales	204457|Sphingomonadales	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4130,UDG
SRD2_k127_5659837_1	685778.AORL01000021_gene696	6.388e-305	960.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2U29S@28211|Alphaproteobacteria,2K0TJ@204457|Sphingomonadales	204457|Sphingomonadales	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRD2_k127_5659837_4	1174684.EBMC1_08421	9.096e-192	608.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,2U15C@28211|Alphaproteobacteria,2K2WX@204457|Sphingomonadales	204457|Sphingomonadales	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SRD2_k127_5659837_23	1449076.JOOE01000001_gene2245	3.274e-24	105.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,2U15C@28211|Alphaproteobacteria,2K2WX@204457|Sphingomonadales	204457|Sphingomonadales	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SRD2_k127_5677316_0	1123267.JONN01000001_gene1061	0.0	1467.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2TQPT@28211|Alphaproteobacteria,2K1B6@204457|Sphingomonadales	204457|Sphingomonadales	CE	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
SRD2_k127_5677316_1	745310.G432_16255	1.886e-218	687.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria,2K1MX@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRD2_k127_5772131_1	1096930.L284_18205	4.553e-227	708.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2TQJ7@28211|Alphaproteobacteria,2K0B7@204457|Sphingomonadales	204457|Sphingomonadales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
SRD2_k127_5772131_10	1123267.JONN01000001_gene1634	9.349e-86	287.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2TUI7@28211|Alphaproteobacteria,2K47C@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRD2_k127_5772131_4	1174684.EBMC1_12771	5.745e-160	517.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2TW1S@28211|Alphaproteobacteria,2K09D@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD2_k127_5772131_6	745310.G432_00860	1.545e-149	489.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2KCM1@204457|Sphingomonadales	204457|Sphingomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRD2_k127_5772131_13	1123267.JONN01000001_gene464	2.818e-43	160.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2UBR5@28211|Alphaproteobacteria,2K633@204457|Sphingomonadales	204457|Sphingomonadales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	ihfB	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRD2_k127_5772131_0	1123267.JONN01000001_gene463	3.331e-316	980.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2TQPV@28211|Alphaproteobacteria,2K0KT@204457|Sphingomonadales	204457|Sphingomonadales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRD2_k127_5772131_14	492774.JQMB01000018_gene3608	9.812e-42	165.0	COG0454@1|root,COG0456@2|Bacteria,1PG3T@1224|Proteobacteria,2V3M0@28211|Alphaproteobacteria,4BFHI@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD2_k127_5772131_12	1123267.JONN01000002_gene223	4.108e-55	198.0	COG2340@1|root,COG2340@2|Bacteria,1N9SZ@1224|Proteobacteria,2UTM1@28211|Alphaproteobacteria,2KE6B@204457|Sphingomonadales	204457|Sphingomonadales	S	SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains.	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRD2_k127_5772131_9	1219035.NT2_07_00590	3.667e-87	311.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,2K0KA@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
SRD2_k127_5772131_5	864069.MicloDRAFT_00051970	2.269e-154	492.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,2TRUA@28211|Alphaproteobacteria,1JQU4@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Hydrolase_4
SRD2_k127_5772131_2	717785.HYPMC_0854	3.08e-200	638.0	COG0492@1|root,COG0664@1|root,COG0492@2|Bacteria,COG0664@2|Bacteria,1MVX2@1224|Proteobacteria,2TQN3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	OT	Pyridine nucleotide-disulphide oxidoreductase	MA20_21135	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,cNMP_binding
SRD2_k127_5772131_7	1449076.JOOE01000002_gene894	5.828e-128	427.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2KCM1@204457|Sphingomonadales	204457|Sphingomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRD2_k127_5772131_11	1123267.JONN01000001_gene1584	1.445e-69	244.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,2U71H@28211|Alphaproteobacteria,2K3ZM@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRD2_k127_5772131_8	1090318.ATTI01000001_gene209	5.818e-125	409.0	COG2267@1|root,COG2267@2|Bacteria,1QU3E@1224|Proteobacteria,2TVXS@28211|Alphaproteobacteria,2KEPE@204457|Sphingomonadales	204457|Sphingomonadales	I	Serine aminopeptidase, S33	-	-	3.5.1.101	ko:K18457	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
SRD2_k127_5772131_15	1030157.AFMP01000031_gene2918	5.128e-35	139.0	COG4530@1|root,COG4530@2|Bacteria,1N42Z@1224|Proteobacteria,2UDI6@28211|Alphaproteobacteria,2K62H@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (FYDLN_acid)	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
SRD2_k127_5772131_3	666685.R2APBS1_1401	2.655e-194	619.0	COG2382@1|root,COG2382@2|Bacteria,1R6XH@1224|Proteobacteria,1SPDA@1236|Gammaproteobacteria,1X4S9@135614|Xanthomonadales	135614|Xanthomonadales	P	Enterochelin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRD2_k127_5772131_16	1123267.JONN01000001_gene744	1.419e-22	102.0	2DHDJ@1|root,2ZZBS@2|Bacteria,1P6FB@1224|Proteobacteria,2UWYW@28211|Alphaproteobacteria,2KBPW@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_583933_13	392499.Swit_2148	7.63e-37	151.0	2E5AF@1|root,3302M@2|Bacteria,1NEU4@1224|Proteobacteria,2UI3N@28211|Alphaproteobacteria,2K5G5@204457|Sphingomonadales	204457|Sphingomonadales	S	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
SRD2_k127_583933_12	392499.Swit_0053	2.074e-38	150.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2U97J@28211|Alphaproteobacteria,2K5X1@204457|Sphingomonadales	204457|Sphingomonadales	C	Ferredoxin	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
SRD2_k127_583933_5	1123267.JONN01000001_gene1102	5.884e-142	464.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,2K05P@204457|Sphingomonadales	204457|Sphingomonadales	E	overlaps another CDS with the same product name	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRD2_k127_583933_7	1123267.JONN01000001_gene1101	1.791e-125	413.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,2JZZX@204457|Sphingomonadales	204457|Sphingomonadales	E	overlaps another CDS with the same product name	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRD2_k127_583933_6	1123267.JONN01000001_gene1100	1.895e-129	416.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2TRMI@28211|Alphaproteobacteria,2JZVR@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha Beta	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
SRD2_k127_583933_8	1123267.JONN01000001_gene1097	4.026e-119	390.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2K27R@204457|Sphingomonadales	204457|Sphingomonadales	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD2_k127_583933_1	1123267.JONN01000001_gene1096	1.3e-202	640.0	COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,2TSKB@28211|Alphaproteobacteria,2K02Y@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Orn Lys Arg decarboxylase class-II family	speF	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRD2_k127_583933_2	1123267.JONN01000001_gene1095	2.456e-199	626.0	COG1899@1|root,COG1899@2|Bacteria,1MVC6@1224|Proteobacteria,2TTRW@28211|Alphaproteobacteria,2K1R2@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
SRD2_k127_583933_0	685778.AORL01000022_gene1614	7.986e-215	677.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,2TS7R@28211|Alphaproteobacteria,2K2R0@204457|Sphingomonadales	204457|Sphingomonadales	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
SRD2_k127_583933_9	196490.AUEZ01000049_gene20	4.113e-99	339.0	COG0477@1|root,COG2814@2|Bacteria,1QTW0@1224|Proteobacteria,2TSC6@28211|Alphaproteobacteria,3JVT2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRD2_k127_583933_14	1123267.JONN01000001_gene1093	6.993e-35	138.0	COG5331@1|root,COG5331@2|Bacteria,1N0MD@1224|Proteobacteria,2U9ZR@28211|Alphaproteobacteria,2K571@204457|Sphingomonadales	204457|Sphingomonadales	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
SRD2_k127_583933_4	1123267.JONN01000001_gene1092	6.14e-159	517.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2TR40@28211|Alphaproteobacteria,2K0YT@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
SRD2_k127_583933_3	1123267.JONN01000001_gene1091	1.009e-175	561.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2TT58@28211|Alphaproteobacteria,2K1P3@204457|Sphingomonadales	204457|Sphingomonadales	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	-	-	-	-	-	-	-	-	-	-	Carb_kinase,YjeF_N
SRD2_k127_583933_10	1123267.JONN01000001_gene1090	3.059e-98	329.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2TUFV@28211|Alphaproteobacteria,2K1QE@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRD2_k127_583933_11	1123267.JONN01000001_gene1089	6.37e-82	284.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2TQV5@28211|Alphaproteobacteria,2K0KS@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19
SRD2_k127_5933584_10	1123267.JONN01000002_gene22	7.201e-100	332.0	COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,2TTC4@28211|Alphaproteobacteria,2K27K@204457|Sphingomonadales	204457|Sphingomonadales	S	Phenylacetic acid catabolic protein	-	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRD2_k127_5933584_17	1382303.JPOM01000001_gene2163	6.697e-51	186.0	COG3247@1|root,COG3247@2|Bacteria,1RH69@1224|Proteobacteria,2U93B@28211|Alphaproteobacteria,2KJ8A@204458|Caulobacterales	204458|Caulobacterales	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
SRD2_k127_5933584_22	1088721.NSU_3805	2.455e-41	156.0	COG2050@1|root,COG2050@2|Bacteria,1RH35@1224|Proteobacteria,2U5QW@28211|Alphaproteobacteria,2K6MG@204457|Sphingomonadales	204457|Sphingomonadales	Q	Thioesterase superfamily	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
SRD2_k127_5933584_9	1123267.JONN01000002_gene224	5.556e-114	372.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2TUXD@28211|Alphaproteobacteria,2K0UE@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRD2_k127_5933584_14	1292034.OR37_00448	5.746e-76	269.0	2DBHB@1|root,2Z98D@2|Bacteria,1QZEM@1224|Proteobacteria,2TY7S@28211|Alphaproteobacteria,2KK84@204458|Caulobacterales	204458|Caulobacterales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
SRD2_k127_5933584_12	1123269.NX02_26350	2.631e-87	295.0	COG1917@1|root,COG1917@2|Bacteria,1N3S2@1224|Proteobacteria,2VFT8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Aspartyl/Asparaginyl beta-hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Arg_Hydrox
SRD2_k127_5933584_23	765698.Mesci_0196	3.705e-37	143.0	COG1765@1|root,COG1765@2|Bacteria,1NVUS@1224|Proteobacteria,2URXQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	OsmC-like protein	attW	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRD2_k127_5933584_29	1054213.HMPREF9946_03686	2.437e-17	82.0	2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,2UGKQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3309
SRD2_k127_5933584_6	1112216.JH594426_gene3803	2.063e-134	445.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2TT2N@28211|Alphaproteobacteria,2K142@204457|Sphingomonadales	204457|Sphingomonadales	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRD2_k127_5933584_4	1123270.ATUR01000003_gene1159	1.353e-203	640.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2TSK3@28211|Alphaproteobacteria,2JZVP@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD2_k127_5933584_13	234267.Acid_2317	1.158e-78	278.0	COG1171@1|root,COG1171@2|Bacteria,3Y2RI@57723|Acidobacteria	57723|Acidobacteria	E	beta' subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
SRD2_k127_5933584_15	1144307.PMI04_00844	1.171e-72	265.0	COG2246@1|root,COG2246@2|Bacteria,1QUSS@1224|Proteobacteria,2TW63@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_5933584_1	1123267.JONN01000002_gene222	0.0	1050.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,1MWD4@1224|Proteobacteria,2TUPI@28211|Alphaproteobacteria,2K1V8@204457|Sphingomonadales	204457|Sphingomonadales	CI	MaoC like domain	-	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,MaoC_dehydratas
SRD2_k127_5933584_20	266779.Meso_2788	4.938e-42	159.0	COG0517@1|root,COG0517@2|Bacteria,1NMH1@1224|Proteobacteria,2U9D8@28211|Alphaproteobacteria,43M98@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRD2_k127_5933584_21	1123267.JONN01000002_gene221	5.148e-42	160.0	COG0711@1|root,COG0711@2|Bacteria,1N0P5@1224|Proteobacteria,2U5DD@28211|Alphaproteobacteria,2K57Z@204457|Sphingomonadales	204457|Sphingomonadales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF_2	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRD2_k127_5933584_25	392499.Swit_4485	9.841e-32	134.0	COG0711@1|root,COG0711@2|Bacteria,1MZGU@1224|Proteobacteria,2UBVW@28211|Alphaproteobacteria,2K5D0@204457|Sphingomonadales	204457|Sphingomonadales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF_1	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRD2_k127_5933584_27	685778.AORL01000015_gene2360	5.66e-28	114.0	COG0636@1|root,COG0636@2|Bacteria,1MZBU@1224|Proteobacteria,2UFPN@28211|Alphaproteobacteria,2K61N@204457|Sphingomonadales	204457|Sphingomonadales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRD2_k127_5933584_11	1549858.MC45_10075	1.403e-90	304.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2TRNV@28211|Alphaproteobacteria,2K17B@204457|Sphingomonadales	204457|Sphingomonadales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRD2_k127_5933584_30	1449076.JOOE01000002_gene1504	3.413e-17	86.0	COG5336@1|root,COG5336@2|Bacteria,1N2ME@1224|Proteobacteria,2UCBR@28211|Alphaproteobacteria,2K62W@204457|Sphingomonadales	204457|Sphingomonadales	S	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
SRD2_k127_5933584_19	1123267.JONN01000002_gene216	1.946e-43	168.0	2ANQE@1|root,31DQ0@2|Bacteria,1MWJD@1224|Proteobacteria,2U7P7@28211|Alphaproteobacteria,2K5A1@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4163)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4163
SRD2_k127_5933584_28	1123267.JONN01000002_gene215	1.647e-22	105.0	COG3784@1|root,COG3784@2|Bacteria,1Q09W@1224|Proteobacteria,2UCIH@28211|Alphaproteobacteria,2K5RZ@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09978	-	-	-	-	ko00000	-	-	-	DUF1318
SRD2_k127_5933584_2	1123267.JONN01000002_gene213	2e-323	1022.0	COG2911@1|root,COG2911@2|Bacteria,1R6VP@1224|Proteobacteria,2U46Q@28211|Alphaproteobacteria,2KCIH@204457|Sphingomonadales	204457|Sphingomonadales	S	Dicarboxylate transport	-	-	-	-	-	-	-	-	-	-	-	-	DctA-YdbH
SRD2_k127_5933584_3	1123267.JONN01000002_gene208	1.389e-235	733.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2TQUE@28211|Alphaproteobacteria,2K0GV@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRD2_k127_5933584_26	1144307.PMI04_00190	2.49e-31	134.0	COG0784@1|root,COG4251@1|root,COG0784@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria,2TT77@28211|Alphaproteobacteria,2JZXT@204457|Sphingomonadales	204457|Sphingomonadales	T	light-regulated signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HWE_HK,PAS_2,PHY,Response_reg
SRD2_k127_5933584_24	1380391.JIAS01000011_gene4882	2.674e-34	134.0	COG0640@1|root,COG0640@2|Bacteria,1RJ39@1224|Proteobacteria,2UA6C@28211|Alphaproteobacteria,2JXH1@204441|Rhodospirillales	204441|Rhodospirillales	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRD2_k127_5933584_18	1320556.AVBP01000007_gene621	2.828e-45	173.0	COG3832@1|root,COG3832@2|Bacteria,1RAW4@1224|Proteobacteria,2UI5Z@28211|Alphaproteobacteria,43P5K@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRD2_k127_5933584_16	1040989.AWZU01000004_gene7029	5.85e-53	199.0	COG0625@1|root,COG0625@2|Bacteria,1RC4Y@1224|Proteobacteria,2U6JK@28211|Alphaproteobacteria,3JVU5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
SRD2_k127_5933584_5	685778.AORL01000010_gene3176	2.563e-151	486.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria,2K1EY@204457|Sphingomonadales	204457|Sphingomonadales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRD2_k127_5933584_0	1123267.JONN01000002_gene202	0.0	1095.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria,2K1KK@204457|Sphingomonadales	204457|Sphingomonadales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRD2_k127_5933584_8	1123267.JONN01000002_gene201	1.239e-119	387.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2TQZG@28211|Alphaproteobacteria,2K1MK@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD2_k127_5933584_7	194867.ALBQ01000027_gene2785	8.845e-130	421.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2TRTT@28211|Alphaproteobacteria,2K15H@204457|Sphingomonadales	204457|Sphingomonadales	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRD2_k127_6005229_59	1123267.JONN01000002_gene14	6.356e-43	161.0	COG0454@1|root,COG0456@2|Bacteria,1RHB3@1224|Proteobacteria,2UD6D@28211|Alphaproteobacteria,2KEH9@204457|Sphingomonadales	204457|Sphingomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRD2_k127_6005229_53	1123267.JONN01000002_gene15	2.335e-52	189.0	2CVTP@1|root,32SY9@2|Bacteria,1N209@1224|Proteobacteria,2UC8J@28211|Alphaproteobacteria,2K6M8@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1203
SRD2_k127_6005229_23	1449076.JOOE01000004_gene559	9.01e-130	430.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,2K165@204457|Sphingomonadales	204457|Sphingomonadales	FL	Metal binding domain of Ada	ada	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
SRD2_k127_6005229_46	1248917.ANFX01000032_gene904	2.988e-68	243.0	COG1266@1|root,COG1266@2|Bacteria,1RJQW@1224|Proteobacteria,2UB06@28211|Alphaproteobacteria,2K5HR@204457|Sphingomonadales	204457|Sphingomonadales	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRD2_k127_6005229_0	1123267.JONN01000002_gene21	0.0	1170.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2TQTQ@28211|Alphaproteobacteria,2K0DV@204457|Sphingomonadales	204457|Sphingomonadales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
SRD2_k127_6005229_16	1123267.JONN01000002_gene109	3.49e-150	477.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2TR8D@28211|Alphaproteobacteria,2K0D0@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRD2_k127_6005229_28	1123267.JONN01000002_gene106	5.663e-117	384.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2TU4E@28211|Alphaproteobacteria,2K07U@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRD2_k127_6005229_1	1123267.JONN01000002_gene104	0.0	1112.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2TQRQ@28211|Alphaproteobacteria,2K0IA@204457|Sphingomonadales	204457|Sphingomonadales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRD2_k127_6005229_6	1123267.JONN01000002_gene93	6.114e-251	786.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2KEG2@204457|Sphingomonadales	204457|Sphingomonadales	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
SRD2_k127_6005229_44	1007104.SUS17_3360	3.349e-77	265.0	COG3233@1|root,COG3233@2|Bacteria,1RG07@1224|Proteobacteria,2VERM@28211|Alphaproteobacteria,2KDTF@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein conserved in bacteria (DUF2334)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2334
SRD2_k127_6005229_22	1081640.AGFU01000075_gene3330	9.65e-132	436.0	COG0438@1|root,COG0438@2|Bacteria,1NU0D@1224|Proteobacteria,2U2M4@28211|Alphaproteobacteria,2K040@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyltransferase Family 4	-	-	-	ko:K14335	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRD2_k127_6005229_5	685778.AORL01000021_gene1008	6.58e-255	798.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,2TTBG@28211|Alphaproteobacteria,2K2S9@204457|Sphingomonadales	204457|Sphingomonadales	P	Chloride channel protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Voltage_CLC
SRD2_k127_6005229_19	1123269.NX02_28585	2.183e-141	462.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2TRPZ@28211|Alphaproteobacteria,2K1SR@204457|Sphingomonadales	204457|Sphingomonadales	J	Polynucleotide adenylyltransferase	cca	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd
SRD2_k127_6005229_48	1449076.JOOE01000001_gene2436	4.205e-65	229.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2TV3Q@28211|Alphaproteobacteria,2K3ZW@204457|Sphingomonadales	204457|Sphingomonadales	L	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRD2_k127_6005229_47	13689.BV96_02635	3.442e-68	236.0	COG3816@1|root,COG3816@2|Bacteria,1RD5Q@1224|Proteobacteria,2U7DA@28211|Alphaproteobacteria,2K0YC@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09986	-	-	-	-	ko00000	-	-	-	DUF1285
SRD2_k127_6005229_41	1123267.JONN01000001_gene888	6.282e-84	286.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2TR0A@28211|Alphaproteobacteria,2K33T@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD2_k127_6005229_56	1123267.JONN01000001_gene889	3.467e-48	175.0	COG1539@1|root,COG1539@2|Bacteria,1PSIE@1224|Proteobacteria,2UD0R@28211|Alphaproteobacteria,2K4H4@204457|Sphingomonadales	204457|Sphingomonadales	H	dihydroneopterin aldolase	-	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRD2_k127_6005229_61	1007104.SUS17_1986	1.572e-35	145.0	COG0810@1|root,COG0810@2|Bacteria,1RCAG@1224|Proteobacteria,2U664@28211|Alphaproteobacteria,2K187@204457|Sphingomonadales	204457|Sphingomonadales	M	Periplasmic protein TonB, links inner and outer membranes	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRD2_k127_6005229_31	1123267.JONN01000001_gene891	7.207e-107	351.0	COG0811@1|root,COG0811@2|Bacteria,1NMPB@1224|Proteobacteria,2TS4F@28211|Alphaproteobacteria,2K1P2@204457|Sphingomonadales	204457|Sphingomonadales	U	MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
SRD2_k127_6005229_55	1335760.ASTG01000005_gene1077	1.32e-51	188.0	COG0848@1|root,COG0848@2|Bacteria,1RH4U@1224|Proteobacteria,2UAMQ@28211|Alphaproteobacteria,2K4K9@204457|Sphingomonadales	204457|Sphingomonadales	U	Biopolymer	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SRD2_k127_6005229_54	1123267.JONN01000001_gene893	6.602e-52	186.0	COG0848@1|root,COG0848@2|Bacteria,1RHDF@1224|Proteobacteria,2UEA0@28211|Alphaproteobacteria,2K55Z@204457|Sphingomonadales	204457|Sphingomonadales	U	Biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SRD2_k127_6005229_11	1123267.JONN01000002_gene49	1.295e-195	620.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2TQPS@28211|Alphaproteobacteria,2K246@204457|Sphingomonadales	204457|Sphingomonadales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
SRD2_k127_6005229_2	1123267.JONN01000002_gene52	5.465e-320	987.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2TQPM@28211|Alphaproteobacteria,2K017@204457|Sphingomonadales	204457|Sphingomonadales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRD2_k127_6005229_12	392499.Swit_3739	1.949e-188	605.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,2TTBG@28211|Alphaproteobacteria,2K15J@204457|Sphingomonadales	204457|Sphingomonadales	P	Chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
SRD2_k127_6005229_68	1129374.AJE_06236	2.076e-13	81.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,464ES@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the peptidase S1C family	degQ	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575	1.3.1.74,3.4.21.107	ko:K04771,ko:K04772,ko:K08070	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
SRD2_k127_6005229_21	1449076.JOOE01000004_gene369	1.374e-134	436.0	COG5285@1|root,COG5285@2|Bacteria,1R7DG@1224|Proteobacteria,2TTB2@28211|Alphaproteobacteria,2K7VF@204457|Sphingomonadales	204457|Sphingomonadales	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRD2_k127_6005229_57	1248760.ANFZ01000004_gene1994	1.381e-46	170.0	COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,2UBRG@28211|Alphaproteobacteria,2K5NY@204457|Sphingomonadales	204457|Sphingomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRD2_k127_6005229_26	392499.Swit_0013	4.561e-121	402.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2TQKD@28211|Alphaproteobacteria,2K0BU@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRD2_k127_6005229_34	1030157.AFMP01000052_gene268	6.057e-100	334.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2TRI2@28211|Alphaproteobacteria,2K0EP@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRD2_k127_6005229_36	204669.Acid345_1475	4.019e-92	332.0	COG0436@1|root,COG0436@2|Bacteria,3Y5AV@57723|Acidobacteria,2JJXH@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRD2_k127_6005229_17	204669.Acid345_1474	1.48e-146	479.0	COG1113@1|root,COG1113@2|Bacteria	2|Bacteria	E	amino acid transport	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRD2_k127_6005229_35	1123267.JONN01000001_gene628	1.656e-96	320.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2TSFJ@28211|Alphaproteobacteria,2K2CC@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRD2_k127_6005229_38	1123267.JONN01000001_gene432	1.192e-90	304.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,2TT1D@28211|Alphaproteobacteria,2K0SX@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRD2_k127_6005229_30	1123267.JONN01000001_gene630	1.259e-108	356.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2TV1Q@28211|Alphaproteobacteria,2K1HB@204457|Sphingomonadales	204457|Sphingomonadales	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRD2_k127_6005229_24	1123267.JONN01000001_gene631	5.224e-127	413.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2TSHM@28211|Alphaproteobacteria,2K01W@204457|Sphingomonadales	204457|Sphingomonadales	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRD2_k127_6005229_42	1123267.JONN01000001_gene632	2.923e-80	276.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2TTIA@28211|Alphaproteobacteria,2K1G1@204457|Sphingomonadales	204457|Sphingomonadales	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRD2_k127_6005229_37	1123267.JONN01000001_gene633	5.576e-91	307.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,2K1QM@204457|Sphingomonadales	204457|Sphingomonadales	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRD2_k127_6005229_10	1123269.NX02_13330	9.297e-196	625.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,2K0KU@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the GPI family	pgi	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRD2_k127_6005229_8	1123267.JONN01000001_gene635	2.071e-211	664.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria,2K11W@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRD2_k127_6005229_62	1122604.JONR01000013_gene3227	4.443e-34	136.0	COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria,1S73M@1236|Gammaproteobacteria,1X6W8@135614|Xanthomonadales	135614|Xanthomonadales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRD2_k127_6005229_4	1123267.JONN01000001_gene636	2.613e-271	848.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,2JZXX@204457|Sphingomonadales	204457|Sphingomonadales	Q	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRD2_k127_6005229_20	1118153.MOY_04018	2.396e-141	461.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,1XHZR@135619|Oceanospirillales	135619|Oceanospirillales	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRD2_k127_6005229_63	745310.G432_01430	6.659e-30	130.0	2ENSP@1|root,33GDV@2|Bacteria,1N3J8@1224|Proteobacteria,2UBZE@28211|Alphaproteobacteria,2K5KK@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6005229_70	485913.Krac_10552	5.76e-07	63.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRD2_k127_6005229_45	1123267.JONN01000001_gene640	6.694e-72	259.0	2F69V@1|root,33YTJ@2|Bacteria,1MYST@1224|Proteobacteria,2UA2M@28211|Alphaproteobacteria,2K4MC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6005229_9	1123267.JONN01000001_gene641	5.186e-197	620.0	COG3853@1|root,COG3853@2|Bacteria,1MY18@1224|Proteobacteria,2TU4T@28211|Alphaproteobacteria,2K07G@204457|Sphingomonadales	204457|Sphingomonadales	P	Toxic anion resistance	-	-	-	-	-	-	-	-	-	-	-	-	TelA
SRD2_k127_6005229_40	1219045.BV98_003779	1.121e-85	299.0	COG4961@1|root,COG4961@2|Bacteria,1QV5Z@1224|Proteobacteria,2TWAQ@28211|Alphaproteobacteria,2K52P@204457|Sphingomonadales	204457|Sphingomonadales	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRD2_k127_6005229_69	1248916.ANFY01000003_gene851	9.954e-13	79.0	COG4961@1|root,COG4961@2|Bacteria,1NJI2@1224|Proteobacteria,2UKY3@28211|Alphaproteobacteria,2K8BZ@204457|Sphingomonadales	204457|Sphingomonadales	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRD2_k127_6005229_66	1123267.JONN01000001_gene644	2e-19	94.0	COG4961@1|root,COG4961@2|Bacteria,1NI9M@1224|Proteobacteria,2UM62@28211|Alphaproteobacteria,2K7R9@204457|Sphingomonadales	204457|Sphingomonadales	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRD2_k127_6005229_39	1123267.JONN01000001_gene645	8.261e-87	302.0	COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,2U2T5@28211|Alphaproteobacteria,2K0VU@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD2_k127_6005229_32	1123267.JONN01000001_gene646	5.328e-102	336.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2TQJB@28211|Alphaproteobacteria,2K0F2@204457|Sphingomonadales	204457|Sphingomonadales	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRD2_k127_6005229_67	1549858.MC45_02295	1.908e-15	78.0	COG3847@1|root,COG3847@2|Bacteria,1Q1G3@1224|Proteobacteria,2V11R@28211|Alphaproteobacteria,2K7TI@204457|Sphingomonadales	204457|Sphingomonadales	U	Flp pilus assembly protein, pilin Flp	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
SRD2_k127_6005229_49	1030157.AFMP01000044_gene1928	1.647e-63	225.0	COG3159@1|root,COG3159@2|Bacteria,1Q6ZX@1224|Proteobacteria,2VD3T@28211|Alphaproteobacteria,2K427@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
SRD2_k127_6005229_25	1123267.JONN01000001_gene648	4.448e-121	401.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,2TS7W@28211|Alphaproteobacteria,2K1R3@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the 'phage' integrase family	xerC_2	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRD2_k127_6005229_15	1081640.AGFU01000018_gene1794	5.283e-153	489.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2TQNE@28211|Alphaproteobacteria,2K0JQ@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
SRD2_k127_6005229_33	1123269.NX02_27830	1.273e-101	337.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2TR14@28211|Alphaproteobacteria,2K0AW@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRD2_k127_6005229_13	1123267.JONN01000001_gene656	8.08e-168	537.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2TT63@28211|Alphaproteobacteria,2K09I@204457|Sphingomonadales	204457|Sphingomonadales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRD2_k127_6005229_43	1123267.JONN01000001_gene657	6.378e-78	266.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2TV4B@28211|Alphaproteobacteria,2K1NS@204457|Sphingomonadales	204457|Sphingomonadales	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRD2_k127_6005229_29	1174684.EBMC1_01400	9.487e-116	379.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2TRMC@28211|Alphaproteobacteria,2K0PW@204457|Sphingomonadales	204457|Sphingomonadales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRD2_k127_6005229_18	1123267.JONN01000001_gene659	3.494e-144	464.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2TRUF@28211|Alphaproteobacteria,2K03N@204457|Sphingomonadales	204457|Sphingomonadales	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
SRD2_k127_6005229_51	1449076.JOOE01000004_gene400	6.095e-56	213.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2U5V2@28211|Alphaproteobacteria,2K3XC@204457|Sphingomonadales	204457|Sphingomonadales	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRD2_k127_6005229_14	1123267.JONN01000001_gene661	2.147e-159	513.0	COG0665@1|root,COG0665@2|Bacteria,1MU7M@1224|Proteobacteria,2U3N5@28211|Alphaproteobacteria,2K4RF@204457|Sphingomonadales	204457|Sphingomonadales	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRD2_k127_6005229_3	1123267.JONN01000001_gene662	3.904e-317	998.0	COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,2U1V9@28211|Alphaproteobacteria,2KEE4@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRD2_k127_6005229_52	452662.SJA_C1-09640	1.2e-55	199.0	COG4253@1|root,COG4253@2|Bacteria,1RJSI@1224|Proteobacteria,2UAVI@28211|Alphaproteobacteria,2K54I@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6005229_60	1549858.MC45_04350	9.149e-36	139.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2UBWW@28211|Alphaproteobacteria,2K5X6@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRD2_k127_6005229_7	1144305.PMI02_01035	5.277e-246	762.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2TR32@28211|Alphaproteobacteria,2JZXI@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRD2_k127_6005229_27	1123267.JONN01000001_gene666	5.013e-117	386.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2TR89@28211|Alphaproteobacteria,2JZXN@204457|Sphingomonadales	204457|Sphingomonadales	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRD2_k127_6005229_64	745310.G432_17460	1.516e-22	103.0	COG0791@1|root,COG0791@2|Bacteria,1MW03@1224|Proteobacteria,2TSFG@28211|Alphaproteobacteria,2K27W@204457|Sphingomonadales	204457|Sphingomonadales	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
SRD2_k127_6005229_50	1123267.JONN01000001_gene668	4.575e-59	206.0	COG1846@1|root,COG1846@2|Bacteria,1RJNN@1224|Proteobacteria,2U9SQ@28211|Alphaproteobacteria,2KDEK@204457|Sphingomonadales	204457|Sphingomonadales	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRD2_k127_6005229_58	627192.SLG_32850	7.929e-45	164.0	COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,2TSI6@28211|Alphaproteobacteria,2JZV7@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the peptidase M17 family	-	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17
SRD2_k127_6098011_0	1123267.JONN01000002_gene136	0.0	1353.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2TQZU@28211|Alphaproteobacteria,2JZX4@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRD2_k127_6098011_6	1123267.JONN01000002_gene135	2.091e-196	617.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2TR3W@28211|Alphaproteobacteria,2K02X@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRD2_k127_6098011_24	1123267.JONN01000002_gene134	2.004e-59	209.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2U7DJ@28211|Alphaproteobacteria,2K3W5@204457|Sphingomonadales	204457|Sphingomonadales	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRD2_k127_6098011_2	1123267.JONN01000002_gene132	2.179e-219	696.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2TRU2@28211|Alphaproteobacteria,2K0VR@204457|Sphingomonadales	204457|Sphingomonadales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_4,Toprim_N,zf-CHC2
SRD2_k127_6098011_1	627192.SLG_24150	2.922e-315	977.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2TS6C@28211|Alphaproteobacteria,2K260@204457|Sphingomonadales	204457|Sphingomonadales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD2_k127_6098011_34	1121124.JNIX01000016_gene2122	1.528e-17	90.0	2F0QW@1|root,33TTA@2|Bacteria,1NCW4@1224|Proteobacteria,2UI5R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6098011_40	485913.Krac_0621	2.96e-06	56.0	2BHPS@1|root,32BT1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6098011_41	693986.MOC_5661	5.99e-06	56.0	COG3103@1|root,COG3103@2|Bacteria,1NCWH@1224|Proteobacteria,2V0DM@28211|Alphaproteobacteria,1JVU5@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Protein of unknown function (DUF3761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3761
SRD2_k127_6098011_31	1449076.JOOE01000001_gene1960	4.593e-28	118.0	2AY5B@1|root,31Q79@2|Bacteria,1NF1Q@1224|Proteobacteria,2UH21@28211|Alphaproteobacteria,2KCFQ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6098011_27	13690.CP98_01915	6.807e-42	164.0	2AK5K@1|root,31AVG@2|Bacteria,1REG7@1224|Proteobacteria,2U8E6@28211|Alphaproteobacteria,2K5AP@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	-
SRD2_k127_6098011_18	158500.BV97_04396	2.796e-72	253.0	COG0265@1|root,COG0265@2|Bacteria,1R55B@1224|Proteobacteria,2U3H7@28211|Alphaproteobacteria,2K0CF@204457|Sphingomonadales	2|Bacteria	O	Trypsin-like peptidase domain	-	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
SRD2_k127_6098011_19	1042326.AZNV01000013_gene3369	1.85e-71	246.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U5Q0@28211|Alphaproteobacteria,4BCA3@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	SelR domain	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRD2_k127_6098011_13	1112212.JH584235_gene782	4.491e-103	355.0	2E384@1|root,32Y7U@2|Bacteria,1N36R@1224|Proteobacteria,2UW56@28211|Alphaproteobacteria,2K1PQ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	ko:K18546	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
SRD2_k127_6098011_22	479433.Caci_8382	1.109e-61	214.0	COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
SRD2_k127_6098011_35	627192.SLG_30620	6.771e-15	77.0	COG1983@1|root,COG1983@2|Bacteria,1NK8Q@1224|Proteobacteria,2UNBI@28211|Alphaproteobacteria,2K844@204457|Sphingomonadales	204457|Sphingomonadales	KT	PspC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PspC
SRD2_k127_6098011_21	1123267.JONN01000002_gene343	1.68e-64	228.0	29636@1|root,2ZTDK@2|Bacteria,1RFN7@1224|Proteobacteria,2U8TB@28211|Alphaproteobacteria,2K5I9@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6098011_3	1123267.JONN01000002_gene341	3.564e-217	682.0	COG0840@1|root,COG0840@2|Bacteria,1NJXF@1224|Proteobacteria,2TTNX@28211|Alphaproteobacteria,2K1FW@204457|Sphingomonadales	204457|Sphingomonadales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
SRD2_k127_6098011_4	1123269.NX02_16500	1.129e-213	668.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,2U1KM@28211|Alphaproteobacteria,2K0PB@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
SRD2_k127_6098011_29	1123269.NX02_16505	1.818e-37	149.0	2DPQ0@1|root,332XN@2|Bacteria,1R3DX@1224|Proteobacteria,2UHFZ@28211|Alphaproteobacteria,2KEWP@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6098011_8	1123267.JONN01000001_gene1115	1.076e-163	522.0	COG3829@1|root,COG3829@2|Bacteria,1QUPP@1224|Proteobacteria,2TR58@28211|Alphaproteobacteria,2K0CK@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain	pspF	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
SRD2_k127_6098011_15	1123267.JONN01000001_gene1114	2.79e-93	310.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,2U6CN@28211|Alphaproteobacteria,2K2DP@204457|Sphingomonadales	204457|Sphingomonadales	KT	Phage shock protein A	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRD2_k127_6098011_30	1123267.JONN01000001_gene1113	1.169e-31	125.0	2EH78@1|root,33AZ2@2|Bacteria,1N7AP@1224|Proteobacteria,2UGJI@28211|Alphaproteobacteria,2K6SQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Phage shock protein B	pspB	-	-	ko:K03970	-	-	-	-	ko00000,ko02048	-	-	-	PspB
SRD2_k127_6098011_26	1123267.JONN01000001_gene1112	1.852e-48	179.0	COG1983@1|root,COG1983@2|Bacteria,1RHXA@1224|Proteobacteria,2UA9Z@28211|Alphaproteobacteria,2K54F@204457|Sphingomonadales	204457|Sphingomonadales	KT	PspC domain	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
SRD2_k127_6098011_32	1248760.ANFZ01000009_gene880	2.606e-26	112.0	28X1J@1|root,344AU@2|Bacteria,1N404@1224|Proteobacteria,2UC94@28211|Alphaproteobacteria,2K65T@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6098011_38	1123267.JONN01000001_gene1111	3.061e-11	69.0	2B2V7@1|root,31VFS@2|Bacteria,1NBPZ@1224|Proteobacteria,2UGTR@28211|Alphaproteobacteria,2KCC5@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6098011_37	1120705.FG95_01415	1.249e-11	68.0	2DNTE@1|root,32Z25@2|Bacteria,1NC1W@1224|Proteobacteria,2UGD6@28211|Alphaproteobacteria,2KCC6@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6098011_42	1248917.ANFX01000051_gene454	4.131e-05	49.0	2B2V7@1|root,31VFS@2|Bacteria,1NBPZ@1224|Proteobacteria,2UGTR@28211|Alphaproteobacteria,2KCC5@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6098011_23	279238.Saro_1164	1.815e-59	208.0	COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,2U9A2@28211|Alphaproteobacteria,2K4H9@204457|Sphingomonadales	204457|Sphingomonadales	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
SRD2_k127_6098011_17	1123267.JONN01000001_gene1107	3.917e-79	270.0	COG2214@1|root,COG2214@2|Bacteria,1RHBK@1224|Proteobacteria,2TYF4@28211|Alphaproteobacteria,2KEMB@204457|Sphingomonadales	204457|Sphingomonadales	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
SRD2_k127_6098011_11	1123267.JONN01000002_gene318	1.288e-123	401.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2TSW3@28211|Alphaproteobacteria,2K0W6@204457|Sphingomonadales	204457|Sphingomonadales	V	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
SRD2_k127_6098011_10	1123267.JONN01000002_gene317	2.024e-129	418.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2TRQ3@28211|Alphaproteobacteria,2K3X1@204457|Sphingomonadales	204457|Sphingomonadales	NT	COG1352 Methylase of chemotaxis methyl-accepting proteins	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR
SRD2_k127_6098011_12	1123267.JONN01000002_gene316	2.319e-121	401.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2TSGV@28211|Alphaproteobacteria,2K0GS@204457|Sphingomonadales	204457|Sphingomonadales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SRD2_k127_6098011_20	1123267.JONN01000002_gene315	5.927e-70	237.0	COG0745@1|root,COG0745@2|Bacteria,1QU38@1224|Proteobacteria,2TVXD@28211|Alphaproteobacteria,2KEGQ@204457|Sphingomonadales	204457|Sphingomonadales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SRD2_k127_6098011_25	1123267.JONN01000002_gene314	2.838e-55	197.0	COG0835@1|root,COG0835@2|Bacteria,1N88R@1224|Proteobacteria,2UGI7@28211|Alphaproteobacteria,2K55G@204457|Sphingomonadales	204457|Sphingomonadales	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRD2_k127_6098011_5	1144307.PMI04_03910	1.853e-211	681.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2TSN2@28211|Alphaproteobacteria,2K0Z1@204457|Sphingomonadales	204457|Sphingomonadales	NT	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SRD2_k127_6098011_16	1123267.JONN01000002_gene246	4.93e-92	308.0	COG5385@1|root,COG5385@2|Bacteria,1MVEY@1224|Proteobacteria,2TSE6@28211|Alphaproteobacteria,2K0H0@204457|Sphingomonadales	204457|Sphingomonadales	S	Histidine phosphotransferase C-terminal domain	-	-	-	ko:K13588	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001	-	-	-	HPTransfase
SRD2_k127_6098011_9	1123267.JONN01000002_gene245	6.156e-147	481.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2TSBK@28211|Alphaproteobacteria,2K1VU@204457|Sphingomonadales	204457|Sphingomonadales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRD2_k127_6098011_7	1123267.JONN01000002_gene244	1.757e-168	532.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2TR9Q@28211|Alphaproteobacteria,2K1G6@204457|Sphingomonadales	204457|Sphingomonadales	K	RNA polymerase sigma	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
SRD2_k127_6098011_14	1549858.MC45_09690	8.816e-100	338.0	COG0546@1|root,COG1295@1|root,COG0546@2|Bacteria,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,2TSFP@28211|Alphaproteobacteria,2K0P0@204457|Sphingomonadales	204457|Sphingomonadales	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	HAD_2,Virul_fac_BrkB
SRD2_k127_6098011_28	1123267.JONN01000002_gene242	6.091e-38	146.0	COG0480@1|root,COG0480@2|Bacteria,1MU2W@1224|Proteobacteria,2TYVK@28211|Alphaproteobacteria,2K1XU@204457|Sphingomonadales	204457|Sphingomonadales	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
SRD2_k127_6117039_0	1112216.JH594425_gene2026	0.0	1010.0	COG0726@1|root,COG1215@1|root,COG3858@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,COG3858@2|Bacteria,1MXG7@1224|Proteobacteria,2TVZ5@28211|Alphaproteobacteria,2K1ER@204457|Sphingomonadales	204457|Sphingomonadales	GM	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_18,Glyco_tranf_2_3,Polysacc_deac_1
SRD2_k127_6117039_3	1123267.JONN01000001_gene1010	1.699e-30	124.0	COG3631@1|root,COG3631@2|Bacteria,1RD0K@1224|Proteobacteria,2UGFJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRD2_k127_6117039_1	1549858.MC45_15935	4.209e-39	150.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2U98H@28211|Alphaproteobacteria,2K6Q8@204457|Sphingomonadales	204457|Sphingomonadales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRD2_k127_6161156_7	935863.AWZR01000001_gene1995	6.25e-08	63.0	2919Q@1|root,2ZNWS@2|Bacteria,1NAF5@1224|Proteobacteria,1T66P@1236|Gammaproteobacteria,1X925@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6161156_5	331869.BAL199_16208	5.939e-46	172.0	2E129@1|root,32WI1@2|Bacteria,1NVE4@1224|Proteobacteria,2URU9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRD2_k127_6161156_6	1123267.JONN01000001_gene771	2.18e-45	177.0	COG3798@1|root,COG3798@2|Bacteria,1N0BJ@1224|Proteobacteria,2UDJF@28211|Alphaproteobacteria,2KE5H@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein conserved in bacteria (DUF2171)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2171
SRD2_k127_6161156_1	1123267.JONN01000001_gene770	3.284e-144	465.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2TQYM@28211|Alphaproteobacteria,2K21X@204457|Sphingomonadales	204457|Sphingomonadales	L	alcohol dehydrogenase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
SRD2_k127_6161156_3	1335760.ASTG01000001_gene3101	9.266e-98	327.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2TRCS@28211|Alphaproteobacteria,2K20W@204457|Sphingomonadales	204457|Sphingomonadales	S	metalloprotease	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRD2_k127_6161156_2	1550073.JROH01000036_gene2656	1.451e-115	377.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,2K16P@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
SRD2_k127_6161156_4	1123267.JONN01000001_gene767	5.461e-49	189.0	2E21J@1|root,32X9B@2|Bacteria,1N5A7@1224|Proteobacteria,2UF1K@28211|Alphaproteobacteria,2K5FT@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4893)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4893
SRD2_k127_6161156_0	745310.G432_03975	2.693e-163	525.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,2K0AI@204457|Sphingomonadales	204457|Sphingomonadales	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRD2_k127_6217408_44	1449076.JOOE01000001_gene2759	1.014e-27	125.0	2DPYS@1|root,33403@2|Bacteria,1N637@1224|Proteobacteria,2UEN9@28211|Alphaproteobacteria,2K6J2@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6217408_36	1219035.NT2_02_00550	6.22e-55	198.0	COG1225@1|root,COG1225@2|Bacteria,1RHSM@1224|Proteobacteria,2U9FF@28211|Alphaproteobacteria,2K56N@204457|Sphingomonadales	204457|Sphingomonadales	O	Peroxiredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRD2_k127_6217408_42	450851.PHZ_c3035	2.16e-44	166.0	COG5579@1|root,COG5579@2|Bacteria,1RGXV@1224|Proteobacteria,2U9EH@28211|Alphaproteobacteria,2KIZV@204458|Caulobacterales	204458|Caulobacterales	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
SRD2_k127_6217408_17	1219045.BV98_001498	6.71e-134	435.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2TRDT@28211|Alphaproteobacteria,2K203@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD2_k127_6217408_49	1123267.JONN01000001_gene2175	3.878e-16	81.0	2CIBQ@1|root,300DF@2|Bacteria,1PBAP@1224|Proteobacteria,2UYXT@28211|Alphaproteobacteria,2K7A4@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6217408_5	1123269.NX02_23410	1.699e-258	810.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2UQAG@28211|Alphaproteobacteria,2K16I@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRD2_k127_6217408_9	1112216.JH594425_gene411	7.914e-197	625.0	2DBJC@1|root,2Z9K5@2|Bacteria,1Q6WE@1224|Proteobacteria,2VCZK@28211|Alphaproteobacteria,2K3G8@204457|Sphingomonadales	204457|Sphingomonadales	S	Glycosyl hydrolase family 47	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_47
SRD2_k127_6217408_4	1120919.AUBI01000020_gene2642	3.674e-274	862.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2TRCK@28211|Alphaproteobacteria,2JPFE@204441|Rhodospirillales	204441|Rhodospirillales	E	Peptidase family M3	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SRD2_k127_6217408_43	1123267.JONN01000001_gene2183	5.277e-34	134.0	COG3453@1|root,COG3453@2|Bacteria,1N9AF@1224|Proteobacteria,2UD2M@28211|Alphaproteobacteria,2K56H@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
SRD2_k127_6217408_54	1120705.FG95_00091	3.341e-06	55.0	2AG1F@1|root,3165I@2|Bacteria,1NGEF@1224|Proteobacteria,2UMPX@28211|Alphaproteobacteria,2K6SM@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
SRD2_k127_6217408_39	392499.Swit_1919	1.694e-51	195.0	COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,2U7AN@28211|Alphaproteobacteria,2K570@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
SRD2_k127_6217408_7	1030157.AFMP01000016_gene2506	3e-237	742.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2TRSR@28211|Alphaproteobacteria,2JZY8@204457|Sphingomonadales	204457|Sphingomonadales	S	peptidase U62, modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRD2_k127_6217408_46	1550073.JROH01000001_gene542	4.356e-24	102.0	COG4391@1|root,COG4391@2|Bacteria,1N7F4@1224|Proteobacteria,2UHY4@28211|Alphaproteobacteria,2K6U4@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
SRD2_k127_6217408_47	1123267.JONN01000001_gene2186	1.195e-20	98.0	2D4N4@1|root,32THB@2|Bacteria,1P3T6@1224|Proteobacteria,2UU52@28211|Alphaproteobacteria,2KB4Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4402
SRD2_k127_6217408_45	1123267.JONN01000001_gene2187	5.272e-25	110.0	2EKFG@1|root,33E5M@2|Bacteria,1NJ6W@1224|Proteobacteria,2UJND@28211|Alphaproteobacteria,2KBN4@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4402
SRD2_k127_6217408_14	1123267.JONN01000001_gene2188	2.255e-148	475.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,2K06G@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD2_k127_6217408_3	1123267.JONN01000001_gene2189	5.848e-283	879.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2TS0E@28211|Alphaproteobacteria,2JZXW@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRD2_k127_6217408_40	1114964.L485_19365	6.569e-50	181.0	COG3686@1|root,COG3686@2|Bacteria,1N00R@1224|Proteobacteria,2U94Y@28211|Alphaproteobacteria,2K6NU@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
SRD2_k127_6217408_21	392499.Swit_2415	9.925e-121	396.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2TSR9@28211|Alphaproteobacteria,2K173@204457|Sphingomonadales	204457|Sphingomonadales	E	ornithine cyclodeaminase	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRD2_k127_6217408_1	745310.G432_11300	0.0	1289.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,2K1KW@204457|Sphingomonadales	204457|Sphingomonadales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRD2_k127_6217408_11	1123267.JONN01000001_gene2194	5.056e-183	588.0	COG2244@1|root,COG2244@2|Bacteria,1PDRG@1224|Proteobacteria,2TVKM@28211|Alphaproteobacteria,2K0P5@204457|Sphingomonadales	204457|Sphingomonadales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3
SRD2_k127_6217408_6	1207055.C100_13320	3.147e-254	797.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2TRMY@28211|Alphaproteobacteria,2K0R5@204457|Sphingomonadales	204457|Sphingomonadales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRD2_k127_6217408_8	1123267.JONN01000001_gene2196	5.792e-228	725.0	COG5360@1|root,COG5360@2|Bacteria,1MUJ4@1224|Proteobacteria,2TR5G@28211|Alphaproteobacteria,2K1RQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Heparinase	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
SRD2_k127_6217408_23	1123267.JONN01000001_gene2197	4.425e-109	356.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2TQKR@28211|Alphaproteobacteria,2K1ZB@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRD2_k127_6217408_15	1090320.KB900605_gene1258	2.56e-144	469.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2TSIA@28211|Alphaproteobacteria,2K0U7@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRD2_k127_6217408_18	1123267.JONN01000001_gene2200	2.128e-131	427.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2TT75@28211|Alphaproteobacteria,2K0GB@204457|Sphingomonadales	204457|Sphingomonadales	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRD2_k127_6217408_12	1123267.JONN01000001_gene2201	6.618e-179	566.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2TSF7@28211|Alphaproteobacteria,2K0S9@204457|Sphingomonadales	204457|Sphingomonadales	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRD2_k127_6217408_26	1112216.JH594425_gene1070	1.999e-94	321.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2TS3D@28211|Alphaproteobacteria,2K19Y@204457|Sphingomonadales	204457|Sphingomonadales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRD2_k127_6217408_41	1123267.JONN01000001_gene2203	1.691e-49	196.0	COG1587@1|root,COG1587@2|Bacteria,1NMTP@1224|Proteobacteria,2UMED@28211|Alphaproteobacteria,2K52Q@204457|Sphingomonadales	204457|Sphingomonadales	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
SRD2_k127_6217408_32	1123267.JONN01000001_gene2204	7.767e-72	252.0	291EX@1|root,2ZP1S@2|Bacteria,1RF3T@1224|Proteobacteria,2U83Z@28211|Alphaproteobacteria,2K4S8@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mitofilin
SRD2_k127_6217408_19	1123267.JONN01000001_gene2205	2.474e-130	426.0	COG2367@1|root,COG2367@2|Bacteria,1PNSR@1224|Proteobacteria,2U483@28211|Alphaproteobacteria,2K1SY@204457|Sphingomonadales	204457|Sphingomonadales	V	beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2,Peptidase_S13
SRD2_k127_6217408_27	1123267.JONN01000001_gene2206	3.417e-83	281.0	COG3751@1|root,COG3751@2|Bacteria,1NG7K@1224|Proteobacteria,2VG2X@28211|Alphaproteobacteria,2KE11@204457|Sphingomonadales	204457|Sphingomonadales	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	1.14.11.2	ko:K00472	ko00330,ko01100,map00330,map01100	-	R01252	RC00478	ko00000,ko00001,ko01000	-	-	-	2OG-FeII_Oxy_3
SRD2_k127_6217408_10	648757.Rvan_2423	1.102e-189	606.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,3N6K2@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD2_k127_6217408_33	1112214.AHIS01000078_gene3474	3.327e-68	261.0	COG1807@1|root,COG1807@2|Bacteria,1RK4G@1224|Proteobacteria,2U9K9@28211|Alphaproteobacteria,2K39M@204457|Sphingomonadales	204457|Sphingomonadales	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6217408_24	745310.G432_08385	8.612e-105	349.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2TS5X@28211|Alphaproteobacteria,2K0HB@204457|Sphingomonadales	204457|Sphingomonadales	O	Thioredoxin	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_15,TPR_19,TPR_20,Thioredoxin
SRD2_k127_6217408_31	1123267.JONN01000001_gene2208	6.772e-73	253.0	COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,2TQZ4@28211|Alphaproteobacteria,2K0QK@204457|Sphingomonadales	204457|Sphingomonadales	S	to the N-terminal domain of Lon protease	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
SRD2_k127_6217408_13	1090320.KB900605_gene1023	6.379e-152	493.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2TRZU@28211|Alphaproteobacteria,2JZY3@204457|Sphingomonadales	204457|Sphingomonadales	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	-	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
SRD2_k127_6217408_2	1123269.NX02_25960	4.253e-302	944.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2TR48@28211|Alphaproteobacteria,2K02P@204457|Sphingomonadales	204457|Sphingomonadales	D	DNA segregation ATPase FtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRD2_k127_6217408_37	1123267.JONN01000001_gene2137	1.663e-53	196.0	COG2834@1|root,COG2834@2|Bacteria,1RA1S@1224|Proteobacteria,2U58W@28211|Alphaproteobacteria,2K43J@204457|Sphingomonadales	204457|Sphingomonadales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	-	-	-	-	-	-	-	-	-	LolA
SRD2_k127_6217408_16	1123267.JONN01000001_gene2138	1.746e-140	452.0	COG0708@1|root,COG0708@2|Bacteria,1MVMC@1224|Proteobacteria,2TRWQ@28211|Alphaproteobacteria,2K09T@204457|Sphingomonadales	204457|Sphingomonadales	L	exodeoxyribonuclease III	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRD2_k127_6217408_22	1123267.JONN01000001_gene2139	1.87e-118	391.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,2TR82@28211|Alphaproteobacteria,2K0DD@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
SRD2_k127_6217408_29	1550073.JROH01000008_gene1737	6.033e-76	261.0	COG0637@1|root,COG0637@2|Bacteria,1NSPA@1224|Proteobacteria,2U0W3@28211|Alphaproteobacteria,2K05N@204457|Sphingomonadales	204457|Sphingomonadales	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRD2_k127_6217408_30	383381.EH30_13760	9.03e-74	260.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2TR5Z@28211|Alphaproteobacteria,2K0C6@204457|Sphingomonadales	204457|Sphingomonadales	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRD2_k127_6217408_51	1090319.KE386571_gene2735	2.519e-14	81.0	COG0352@1|root,COG0352@2|Bacteria,1MZ0K@1224|Proteobacteria,2UA7U@28211|Alphaproteobacteria,2KCXN@204457|Sphingomonadales	204457|Sphingomonadales	H	Thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SRD2_k127_6217408_34	1123267.JONN01000001_gene2142	1.674e-67	238.0	2C7BT@1|root,33MZ9@2|Bacteria,1NMQ4@1224|Proteobacteria,2UG5B@28211|Alphaproteobacteria,2K40I@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
SRD2_k127_6217408_35	1123267.JONN01000001_gene2143	1.459e-58	206.0	2C2J5@1|root,315UG@2|Bacteria,1RHAH@1224|Proteobacteria,2U94W@28211|Alphaproteobacteria,2K4E5@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF3576)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3576
SRD2_k127_6217408_0	1123267.JONN01000001_gene2144	0.0	1338.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2TQPK@28211|Alphaproteobacteria,2K0Q0@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRD2_k127_6217408_38	1470591.BW41_03494	5.068e-52	190.0	COG5468@1|root,COG5468@2|Bacteria,1MXDR@1224|Proteobacteria,2UB6D@28211|Alphaproteobacteria,2KD8X@204457|Sphingomonadales	204457|Sphingomonadales	S	Lipopolysaccharide-assembly	-	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
SRD2_k127_6217408_28	745310.G432_10090	8.517e-81	284.0	COG1466@1|root,COG1466@2|Bacteria,1N7AB@1224|Proteobacteria,2UHPM@28211|Alphaproteobacteria,2K0ER@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase III	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRD2_k127_6217408_25	745310.G432_10150	1.391e-96	328.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,2K0RQ@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRD2_k127_6217408_20	685778.AORL01000022_gene1601	3.593e-122	397.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2TSWH@28211|Alphaproteobacteria,2K02Z@204457|Sphingomonadales	204457|Sphingomonadales	D	Chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRD2_k127_6217408_48	745310.G432_10160	4.369e-20	92.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2U9T9@28211|Alphaproteobacteria,2K4N2@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRD2_k127_6303307_4	1123267.JONN01000001_gene2018	6.269e-62	216.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2U77Q@28211|Alphaproteobacteria,2K4E6@204457|Sphingomonadales	204457|Sphingomonadales	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
SRD2_k127_6303307_5	1123267.JONN01000001_gene2019	5.778e-44	169.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2U787@28211|Alphaproteobacteria,2K074@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
SRD2_k127_6303307_1	1123267.JONN01000001_gene2020	1.609e-196	627.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TS80@28211|Alphaproteobacteria,2K087@204457|Sphingomonadales	204457|Sphingomonadales	S	COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRD2_k127_6303307_6	1123267.JONN01000001_gene1993	1.497e-36	143.0	COG3743@1|root,COG3743@2|Bacteria,1N76A@1224|Proteobacteria,2U93Q@28211|Alphaproteobacteria,2KD7J@204457|Sphingomonadales	204457|Sphingomonadales	S	NADH ubiquinone oxidoreductase 41 kD complex I subunit	-	-	-	-	-	-	-	-	-	-	-	-	HHH_5
SRD2_k127_6303307_2	1123267.JONN01000001_gene1990	1.507e-190	604.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2TQR5@28211|Alphaproteobacteria,2K0GD@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRD2_k127_6303307_3	1123267.JONN01000001_gene1989	5.633e-187	597.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2TR1R@28211|Alphaproteobacteria,2K05G@204457|Sphingomonadales	204457|Sphingomonadales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRD2_k127_6303307_8	1123267.JONN01000001_gene1988	3.352e-24	106.0	COG3908@1|root,COG3908@2|Bacteria,1N7PA@1224|Proteobacteria,2UFTN@28211|Alphaproteobacteria,2K6ZC@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein conserved in bacteria (DUF2093)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2093
SRD2_k127_6303307_7	1174684.EBMC1_07125	1.791e-29	124.0	2DTSK@1|root,32UVT@2|Bacteria,1N20S@1224|Proteobacteria,2UCXK@28211|Alphaproteobacteria,2K628@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6303307_0	629773.AORY01000014_gene2523	7.871e-198	641.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria,2JZUI@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRD2_k127_6431608_2	1123267.JONN01000002_gene86	2.952e-137	442.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2TS98@28211|Alphaproteobacteria,2K035@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRD2_k127_6431608_4	1313172.YM304_20800	8.69e-85	295.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4CMYC@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRD2_k127_6431608_3	1123267.JONN01000002_gene84	1.096e-109	363.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2TR81@28211|Alphaproteobacteria,2K0CM@204457|Sphingomonadales	204457|Sphingomonadales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRD2_k127_6431608_0	1123267.JONN01000002_gene83	1.521e-236	735.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2TTGS@28211|Alphaproteobacteria,2K0AN@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRD2_k127_6431608_1	1123267.JONN01000002_gene82	2.567e-212	668.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2TR4H@28211|Alphaproteobacteria,2K185@204457|Sphingomonadales	204457|Sphingomonadales	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRD2_k127_6435240_0	716928.AJQT01000058_gene5370	8.025e-262	817.0	COG0028@1|root,COG0028@2|Bacteria,1MWKP@1224|Proteobacteria,2TQK6@28211|Alphaproteobacteria,4BAGA@82115|Rhizobiaceae	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRD2_k127_6435240_2	1040986.ATYO01000003_gene5825	6.163e-128	423.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,43H3D@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Dehydrogenase	lldD	-	1.1.2.3	ko:K00101	ko00620,ko01100,map00620,map01100	-	R00196	RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRD2_k127_6435240_1	187303.BN69_3475	1.875e-258	808.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,2TT3C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
SRD2_k127_6435240_3	1247963.JPHU01000019_gene3010	2.805e-67	234.0	COG2267@1|root,COG2267@2|Bacteria,1RFQV@1224|Proteobacteria,2U7CC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
SRD2_k127_6435240_4	426117.M446_2087	2.907e-63	228.0	28KGV@1|root,2ZA2H@2|Bacteria,1N071@1224|Proteobacteria,2U0QB@28211|Alphaproteobacteria,1JXIQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6451154_2	685778.AORL01000022_gene1314	1.123e-106	349.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2TSDZ@28211|Alphaproteobacteria,2JZY9@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRD2_k127_6451154_0	1123267.JONN01000001_gene754	2.5e-323	1007.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,2TRU4@28211|Alphaproteobacteria,2K02W@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidase M13	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M13,Peptidase_M13_N
SRD2_k127_6451154_1	1123267.JONN01000001_gene754	7.441e-268	839.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,2TRU4@28211|Alphaproteobacteria,2K02W@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidase M13	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M13,Peptidase_M13_N
SRD2_k127_6451154_3	1123267.JONN01000001_gene756	4.828e-40	149.0	COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,2TS9N@28211|Alphaproteobacteria,2K1P6@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	2CSK_N,HATPase_c
SRD2_k127_6543955_1	1123267.JONN01000002_gene251	2.311e-145	483.0	COG2234@1|root,COG2234@2|Bacteria,1R56X@1224|Proteobacteria,2U2G7@28211|Alphaproteobacteria,2K2WC@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRD2_k127_6543955_0	627192.SLG_23720	1.804e-185	584.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria,2K104@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRD2_k127_6543955_2	1120705.FG95_02908	8.975e-84	285.0	COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,2TRH2@28211|Alphaproteobacteria,2K99V@204457|Sphingomonadales	204457|Sphingomonadales	C	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	-	ko:K07336	-	-	-	-	ko00000,ko01000	-	-	-	2OG-FeII_Oxy_3
SRD2_k127_6543955_3	745310.G432_04905	6.006e-18	89.0	2DWG9@1|root,34073@2|Bacteria,1NVA6@1224|Proteobacteria,2URJH@28211|Alphaproteobacteria,2K8JR@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6553364_3	685778.AORL01000009_gene3213	7.273e-80	276.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,2K25R@204457|Sphingomonadales	204457|Sphingomonadales	C	aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRD2_k127_6553364_0	1030157.AFMP01000050_gene14	3.587e-177	571.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2JZZB@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRD2_k127_6553364_1	1123267.JONN01000001_gene1941	5.127e-144	461.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria,2K1JZ@204457|Sphingomonadales	204457|Sphingomonadales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRD2_k127_6553364_2	1123267.JONN01000001_gene1942	4.963e-109	362.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2TRHW@28211|Alphaproteobacteria,2K21E@204457|Sphingomonadales	204457|Sphingomonadales	M	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	ko:K18164	ko04714,map04714	-	-	-	ko00000,ko00001,ko03029	-	-	-	Methyltransf_28
SRD2_k127_6553364_5	194867.ALBQ01000009_gene2316	4.247e-53	192.0	COG0454@1|root,COG0456@2|Bacteria,1MZA6@1224|Proteobacteria,2UCC0@28211|Alphaproteobacteria,2K4CY@204457|Sphingomonadales	204457|Sphingomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRD2_k127_6553364_4	1090320.KB900605_gene1242	7.053e-54	202.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2TTXU@28211|Alphaproteobacteria,2K13X@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRD2_k127_6607233_3	1449049.JONW01000010_gene3729	9.078e-25	107.0	COG1376@1|root,COG1376@2|Bacteria,1Q823@1224|Proteobacteria,2TV64@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRD2_k127_6607233_4	579138.Zymop_1509	7.507e-16	81.0	COG1335@1|root,COG1335@2|Bacteria,1QK2B@1224|Proteobacteria,2U5X9@28211|Alphaproteobacteria,2K43F@204457|Sphingomonadales	204457|Sphingomonadales	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRD2_k127_6607233_2	330214.NIDE0745	4.188e-38	158.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRD2_k127_6607233_0	1123267.JONN01000001_gene784	0.0	1240.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2TRH3@28211|Alphaproteobacteria,2K0IJ@204457|Sphingomonadales	204457|Sphingomonadales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRD2_k127_6607233_1	1219045.BV98_000330	1.433e-39	149.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2UBRZ@28211|Alphaproteobacteria,2K622@204457|Sphingomonadales	204457|Sphingomonadales	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRD2_k127_6615343_35	1123267.JONN01000001_gene1284	2.681e-63	221.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2TS6I@28211|Alphaproteobacteria,2K1PI@204457|Sphingomonadales	204457|Sphingomonadales	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRD2_k127_6615343_46	1123267.JONN01000001_gene1283	8.027e-27	114.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2UCIP@28211|Alphaproteobacteria,2K5YU@204457|Sphingomonadales	204457|Sphingomonadales	U	Preprotein translocase subunit SecG	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRD2_k127_6615343_1	1123267.JONN01000001_gene1282	1.571e-299	924.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2TS4Y@28211|Alphaproteobacteria,2K005@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRD2_k127_6615343_48	685778.AORL01000019_gene1855	3.453e-11	64.0	2EFZF@1|root,339RM@2|Bacteria,1Q79X@1224|Proteobacteria,2UWHC@28211|Alphaproteobacteria,2K7QX@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6615343_13	1123267.JONN01000001_gene1276	9.693e-166	526.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2TRBW@28211|Alphaproteobacteria,2K0I2@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRD2_k127_6615343_22	1123267.JONN01000001_gene962	4.856e-120	390.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2TR57@28211|Alphaproteobacteria,2K0ZD@204457|Sphingomonadales	204457|Sphingomonadales	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRD2_k127_6615343_25	1123267.JONN01000001_gene963	3.308e-109	361.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2TSWX@28211|Alphaproteobacteria,2K0ZM@204457|Sphingomonadales	204457|Sphingomonadales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRD2_k127_6615343_27	1123267.JONN01000001_gene964	3.149e-104	343.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2TRZM@28211|Alphaproteobacteria,2K15N@204457|Sphingomonadales	204457|Sphingomonadales	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRD2_k127_6615343_50	1121022.ABENE_16245	2.521e-08	56.0	COG0346@1|root,COG0346@2|Bacteria,1N08M@1224|Proteobacteria,2UCUW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD2_k127_6615343_30	1123267.JONN01000002_gene149	7.02e-75	255.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2U797@28211|Alphaproteobacteria,2K3Y2@204457|Sphingomonadales	204457|Sphingomonadales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRD2_k127_6615343_40	1096930.L284_20960	2.924e-51	185.0	COG1145@1|root,32SB1@2|Bacteria,1N096@1224|Proteobacteria,2U9JE@28211|Alphaproteobacteria,2K59E@204457|Sphingomonadales	204457|Sphingomonadales	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
SRD2_k127_6615343_12	1470591.BW41_03734	2.183e-171	549.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2TTX6@28211|Alphaproteobacteria,2K0B3@204457|Sphingomonadales	204457|Sphingomonadales	S	DNA recombination protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRD2_k127_6615343_24	1123267.JONN01000001_gene912	1.122e-112	376.0	COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,2TT4Y@28211|Alphaproteobacteria,2K16F@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SRD2_k127_6615343_45	1123267.JONN01000001_gene913	4.83e-27	119.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2UC0H@28211|Alphaproteobacteria,2K638@204457|Sphingomonadales	204457|Sphingomonadales	G	COG1925 Phosphotransferase system, HPr-related proteins	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
SRD2_k127_6615343_36	1030157.AFMP01000019_gene613	1.345e-61	215.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2U9E5@28211|Alphaproteobacteria,2K4MZ@204457|Sphingomonadales	204457|Sphingomonadales	G	PTS fructose transporter subunit IIA	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
SRD2_k127_6615343_20	1123267.JONN01000001_gene915	3.52e-125	408.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2TTI4@28211|Alphaproteobacteria,2K01M@204457|Sphingomonadales	204457|Sphingomonadales	T	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRD2_k127_6615343_37	1123267.JONN01000001_gene916	1.27e-57	204.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2UFPB@28211|Alphaproteobacteria,2K65M@204457|Sphingomonadales	204457|Sphingomonadales	T	Serine kinase of the HPr protein, regulates carbohydrate metabolism	-	-	-	-	-	-	-	-	-	-	-	-	Hpr_kinase_C
SRD2_k127_6615343_8	1123267.JONN01000001_gene917	4.397e-198	632.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2TS69@28211|Alphaproteobacteria,2K1JA@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	2.7.13.3	ko:K14980	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Sensor_TM1,Stimulus_sens_1
SRD2_k127_6615343_23	1090319.KE386571_gene1141	3.781e-113	371.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2TR43@28211|Alphaproteobacteria,2JZVH@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K14981	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD2_k127_6615343_3	1123267.JONN01000001_gene919	7.154e-288	891.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,2TRC4@28211|Alphaproteobacteria,2JZZG@204457|Sphingomonadales	204457|Sphingomonadales	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
SRD2_k127_6615343_39	1449076.JOOE01000001_gene1961	2.35e-53	191.0	2CKCH@1|root,331PP@2|Bacteria,1QYXW@1224|Proteobacteria,2TY15@28211|Alphaproteobacteria,2KEKB@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6615343_18	745310.G432_04360	3.593e-134	448.0	COG1228@1|root,COG1228@2|Bacteria,1R86X@1224|Proteobacteria,2U400@28211|Alphaproteobacteria,2K1TI@204457|Sphingomonadales	204457|Sphingomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRD2_k127_6615343_5	1247963.JPHU01000001_gene1893	1.354e-224	715.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSQN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRD2_k127_6615343_43	1123267.JONN01000001_gene922	2.757e-33	137.0	COG1585@1|root,COG1585@2|Bacteria,1N241@1224|Proteobacteria,2UC8X@28211|Alphaproteobacteria,2K5WQ@204457|Sphingomonadales	204457|Sphingomonadales	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
SRD2_k127_6615343_17	1123267.JONN01000001_gene923	1.246e-143	464.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria,2K2F3@204457|Sphingomonadales	204457|Sphingomonadales	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
SRD2_k127_6615343_28	1123267.JONN01000001_gene924	5.013e-83	284.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria,2K2U8@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRD2_k127_6615343_4	1123267.JONN01000001_gene925	4.095e-254	791.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2TQXC@28211|Alphaproteobacteria,2K0CG@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
SRD2_k127_6615343_16	1123267.JONN01000001_gene926	2.355e-146	473.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2TS6U@28211|Alphaproteobacteria,2K17G@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F
SRD2_k127_6615343_42	1123267.JONN01000001_gene927	2.744e-38	150.0	COG3063@1|root,COG3063@2|Bacteria,1R17W@1224|Proteobacteria,2TYY0@28211|Alphaproteobacteria,2KEPF@204457|Sphingomonadales	204457|Sphingomonadales	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
SRD2_k127_6615343_21	1123267.JONN01000001_gene928	9.671e-121	396.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2TRD9@28211|Alphaproteobacteria,2K042@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRD2_k127_6615343_15	1123267.JONN01000001_gene929	1.052e-154	494.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,2K0HZ@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
SRD2_k127_6615343_11	1123267.JONN01000001_gene930	3.505e-176	563.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2TSJ3@28211|Alphaproteobacteria,2K0UR@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidylprolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N,SurA_N_3
SRD2_k127_6615343_2	1123267.JONN01000001_gene931	1.081e-288	906.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2TR3B@28211|Alphaproteobacteria,2K1GQ@204457|Sphingomonadales	204457|Sphingomonadales	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
SRD2_k127_6615343_10	392499.Swit_0412	3.708e-178	571.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2TQU9@28211|Alphaproteobacteria,2K04B@204457|Sphingomonadales	204457|Sphingomonadales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRD2_k127_6615343_38	1123267.JONN01000001_gene933	2.963e-55	196.0	COG2927@1|root,COG2927@2|Bacteria,1RGVC@1224|Proteobacteria,2U94V@28211|Alphaproteobacteria,2K5Y0@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase III	holC	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
SRD2_k127_6615343_32	702113.PP1Y_AT20481	8.902e-74	250.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2U5CS@28211|Alphaproteobacteria,2K3WY@204457|Sphingomonadales	204457|Sphingomonadales	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRD2_k127_6615343_9	1174684.EBMC1_13366	1.749e-183	585.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2TUW3@28211|Alphaproteobacteria,2K25Z@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
SRD2_k127_6615343_49	13690.CP98_00390	1.255e-08	63.0	2FBT4@1|root,343XW@2|Bacteria,1NV0Z@1224|Proteobacteria,2URIG@28211|Alphaproteobacteria,2K4MR@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6615343_41	1449076.JOOE01000001_gene1820	9.59e-44	162.0	COG3801@1|root,COG3801@2|Bacteria,1PTCF@1224|Proteobacteria,2V58I@28211|Alphaproteobacteria,2K60B@204457|Sphingomonadales	204457|Sphingomonadales	S	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRD2_k127_6615343_34	1112212.JH584235_gene534	1.327e-70	244.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2TRY6@28211|Alphaproteobacteria,2K28Q@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N,YjbR
SRD2_k127_6615343_14	1549858.MC45_03365	3.601e-158	509.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2TR6G@28211|Alphaproteobacteria,2K07H@204457|Sphingomonadales	204457|Sphingomonadales	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRD2_k127_6615343_26	1123267.JONN01000001_gene942	1.925e-108	368.0	COG3249@1|root,COG3249@2|Bacteria,1R81G@1224|Proteobacteria,2U1EP@28211|Alphaproteobacteria,2K0TT@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6615343_29	1123267.JONN01000001_gene943	4.29e-81	283.0	COG0593@1|root,COG0593@2|Bacteria,1N4PG@1224|Proteobacteria,2U96K@28211|Alphaproteobacteria,2K4AT@204457|Sphingomonadales	204457|Sphingomonadales	L	ATPase involved in DNA replication	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA
SRD2_k127_6615343_6	1123267.JONN01000001_gene947	3.019e-207	651.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,2TSQM@28211|Alphaproteobacteria,2K0ID@204457|Sphingomonadales	204457|Sphingomonadales	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SRD2_k127_6615343_0	1537715.JQFJ01000002_gene1060	0.0	1007.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2TR9U@28211|Alphaproteobacteria,2K0PT@204457|Sphingomonadales	204457|Sphingomonadales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRD2_k127_6615343_31	1123267.JONN01000001_gene952	2.713e-74	254.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,2U75V@28211|Alphaproteobacteria,2K3X2@204457|Sphingomonadales	204457|Sphingomonadales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRD2_k127_6615343_7	1123267.JONN01000001_gene953	8.42e-205	657.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2TRDB@28211|Alphaproteobacteria,2K0PK@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
SRD2_k127_6615343_19	1123267.JONN01000001_gene954	1.279e-125	410.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2TR5W@28211|Alphaproteobacteria,2K09B@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRD2_k127_6615343_33	1207055.C100_15085	6.315e-72	246.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2U71I@28211|Alphaproteobacteria,2K3YM@204457|Sphingomonadales	204457|Sphingomonadales	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRD2_k127_6615343_44	1379701.JPJC01000136_gene2734	3.246e-29	123.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,2UB7Z@28211|Alphaproteobacteria,2K4SW@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
SRD2_k127_6665120_6	1449076.JOOE01000001_gene2112	9.803e-61	214.0	COG2850@1|root,COG2850@2|Bacteria,1MUAC@1224|Proteobacteria,2TSG2@28211|Alphaproteobacteria,2K0V1@204457|Sphingomonadales	204457|Sphingomonadales	S	A domain family that is part of the cupin metalloenzyme superfamily.	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
SRD2_k127_6665120_0	1121022.ABENE_16330	3.804e-292	914.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,2TS28@28211|Alphaproteobacteria,2KHQI@204458|Caulobacterales	204458|Caulobacterales	G	PFAM glycoside hydrolase family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRD2_k127_6665120_4	633149.Bresu_2901	2.004e-112	372.0	COG2850@1|root,COG2850@2|Bacteria,1MUAC@1224|Proteobacteria,2U4X2@28211|Alphaproteobacteria,2KK62@204458|Caulobacterales	204458|Caulobacterales	S	A domain family that is part of the cupin metalloenzyme superfamily.	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
SRD2_k127_6665120_7	1123267.JONN01000001_gene625	5.569e-54	199.0	COG3637@1|root,COG3637@2|Bacteria,1N7U7@1224|Proteobacteria,2TXS0@28211|Alphaproteobacteria,2KEJB@204457|Sphingomonadales	204457|Sphingomonadales	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
SRD2_k127_6665120_1	1090318.ATTI01000001_gene1768	6.392e-224	704.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2TRD7@28211|Alphaproteobacteria,2K01R@204457|Sphingomonadales	204457|Sphingomonadales	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRD2_k127_6665120_2	317655.Sala_0753	9.575e-189	600.0	COG3507@1|root,COG3507@2|Bacteria,1R5F2@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
SRD2_k127_6665120_11	886377.Murru_0150	3.569e-12	74.0	2FECF@1|root,346C7@2|Bacteria,4P54D@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6665120_3	450851.PHZ_c3271	2.654e-118	384.0	COG0625@1|root,COG0625@2|Bacteria,1NUET@1224|Proteobacteria,2TRGC@28211|Alphaproteobacteria,2KJCX@204458|Caulobacterales	204458|Caulobacterales	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
SRD2_k127_6665120_5	1123267.JONN01000001_gene1712	2.524e-62	221.0	COG0784@1|root,COG0784@2|Bacteria,1Q8CG@1224|Proteobacteria,2VEIV@28211|Alphaproteobacteria,2K7Z1@204457|Sphingomonadales	204457|Sphingomonadales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRD2_k127_6665120_10	1122970.AUHC01000010_gene1637	3.299e-38	153.0	COG3773@1|root,COG3773@2|Bacteria,1RDSV@1224|Proteobacteria,2U8XY@28211|Alphaproteobacteria,2K4PG@204457|Sphingomonadales	204457|Sphingomonadales	M	COG3773 Cell wall hydrolyses involved in spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
SRD2_k127_6665120_8	1030157.AFMP01000019_gene660	2.884e-51	188.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2U71N@28211|Alphaproteobacteria,2K5EU@204457|Sphingomonadales	204457|Sphingomonadales	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
SRD2_k127_6665120_12	1226994.AMZB01000095_gene642	1.329e-09	67.0	2C67P@1|root,32RGV@2|Bacteria,1RKYU@1224|Proteobacteria,1S8BB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3828)	yqhG	-	-	-	-	-	-	-	-	-	-	-	DUF3828
SRD2_k127_6665120_9	1123267.JONN01000001_gene1714	4.908e-46	166.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2TR63@28211|Alphaproteobacteria,2K169@204457|Sphingomonadales	204457|Sphingomonadales	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRD2_k127_6682566_10	656024.FsymDg_2257	1.982e-64	228.0	COG2132@1|root,COG2132@2|Bacteria,2HTNT@201174|Actinobacteria,4ETQF@85013|Frankiales	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRD2_k127_6682566_2	69395.JQLZ01000004_gene783	2.237e-152	490.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,2TU59@28211|Alphaproteobacteria,2KFZ9@204458|Caulobacterales	204458|Caulobacterales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRD2_k127_6682566_3	69395.JQLZ01000004_gene782	2.225e-135	442.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TR2P@28211|Alphaproteobacteria,2KFF0@204458|Caulobacterales	204458|Caulobacterales	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD2_k127_6682566_9	450851.PHZ_c0717	2.601e-68	244.0	COG0845@1|root,COG0845@2|Bacteria,1R3U4@1224|Proteobacteria,2TW9A@28211|Alphaproteobacteria,2KJVA@204458|Caulobacterales	204458|Caulobacterales	M	HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
SRD2_k127_6682566_7	629773.AORY01000004_gene90	1.302e-111	384.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TSN8@28211|Alphaproteobacteria,2K0XN@204457|Sphingomonadales	204457|Sphingomonadales	MU	COG1538 Outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRD2_k127_6682566_8	1449049.JONW01000005_gene1637	1.013e-70	252.0	COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2TRPA@28211|Alphaproteobacteria,2KH4Q@204458|Caulobacterales	204458|Caulobacterales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRD2_k127_6682566_15	46429.BV95_01648	5.036e-13	74.0	2ARWT@1|root,31H8N@2|Bacteria,1PAA6@1224|Proteobacteria,2UYHM@28211|Alphaproteobacteria,2KBWE@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6682566_13	1547437.LL06_06185	1.102e-21	96.0	COG4391@1|root,COG4391@2|Bacteria,1MZNK@1224|Proteobacteria,2UD0H@28211|Alphaproteobacteria,43KN5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Zinc-finger domain	MA20_32275	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
SRD2_k127_6682566_14	1121028.ARQE01000014_gene147	1.058e-18	87.0	28W9K@1|root,2ZIA4@2|Bacteria,1PAX5@1224|Proteobacteria,2UWZK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6682566_23	1380394.JADL01000012_gene851	0.0003521	45.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRD2_k127_6682566_20	158500.BV97_02530	5.907e-05	49.0	2BMNS@1|root,32G80@2|Bacteria,1NMXA@1224|Proteobacteria,2UNGA@28211|Alphaproteobacteria,2K7TQ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
SRD2_k127_6682566_19	748280.NH8B_1148	2.535e-08	55.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6682566_5	1112212.JH584235_gene3566	4.639e-114	372.0	COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,2TTZV@28211|Alphaproteobacteria,2K1FS@204457|Sphingomonadales	204457|Sphingomonadales	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
SRD2_k127_6682566_6	317655.Sala_0591	8.552e-114	375.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,2TS67@28211|Alphaproteobacteria,2K0NC@204457|Sphingomonadales	204457|Sphingomonadales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRD2_k127_6682566_11	1030157.AFMP01000052_gene131	5.284e-36	138.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria,2K5YV@204457|Sphingomonadales	204457|Sphingomonadales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRD2_k127_6682566_18	1545915.JROG01000004_gene2452	3.705e-09	68.0	2AE8J@1|root,3142J@2|Bacteria,1P7XY@1224|Proteobacteria,2UX9M@28211|Alphaproteobacteria,2K7W8@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6682566_12	1411123.JQNH01000001_gene2204	2.96e-30	131.0	2EMWB@1|root,33FIJ@2|Bacteria,1R3GB@1224|Proteobacteria,2U02P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SRD2_k127_6682566_0	1123267.JONN01000001_gene1733	0.0	1036.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,2K0RP@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
SRD2_k127_6682566_4	1123267.JONN01000001_gene1716	3.246e-133	436.0	COG0477@1|root,COG2814@2|Bacteria,1NGB4@1224|Proteobacteria,2TWAK@28211|Alphaproteobacteria,2K8XV@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRD2_k127_6682566_22	596152.DesU5LDRAFT_1786	0.0001119	52.0	COG1846@1|root,COG1846@2|Bacteria,1NI1U@1224|Proteobacteria,42XXC@68525|delta/epsilon subdivisions,2WSPF@28221|Deltaproteobacteria,2MBMC@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Regulatory protein MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRD2_k127_6682566_16	1094715.CM001373_gene1601	1.587e-10	63.0	COG3668@1|root,32ZH9@2|Bacteria,1N7YH@1224|Proteobacteria,1SDBR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG3668 Plasmid stabilization system protein	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
SRD2_k127_6682566_1	555217.Zmob_1644	3.836e-261	812.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2TR63@28211|Alphaproteobacteria,2K169@204457|Sphingomonadales	204457|Sphingomonadales	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRD2_k127_6708918_21	702113.PP1Y_AT4889	2.443e-22	98.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2TR8J@28211|Alphaproteobacteria,2K18B@204457|Sphingomonadales	204457|Sphingomonadales	S	Aminomethyltransferase	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T
SRD2_k127_6708918_14	1144307.PMI04_02379	1.583e-92	312.0	COG1878@1|root,COG1878@2|Bacteria,1R8IH@1224|Proteobacteria,2U9RH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRD2_k127_6708918_22	1280949.HAD_01410	1.579e-20	95.0	2EFVT@1|root,339N0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Imp-YgjV
SRD2_k127_6708918_0	1123267.JONN01000001_gene2385	0.0	1467.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,2K0CP@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRD2_k127_6708918_13	1123267.JONN01000001_gene2382	1.863e-102	350.0	COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,2TQQD@28211|Alphaproteobacteria,2K4ZK@204457|Sphingomonadales	204457|Sphingomonadales	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRD2_k127_6708918_19	1090320.KB900605_gene2110	3.379e-57	204.0	29CWT@1|root,2ZZUX@2|Bacteria,1REF2@1224|Proteobacteria,2U7K7@28211|Alphaproteobacteria,2K4SS@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2585)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2585
SRD2_k127_6708918_20	1123267.JONN01000001_gene2379	7.896e-56	200.0	2BYSU@1|root,32R3U@2|Bacteria,1MZ0R@1224|Proteobacteria,2U9AE@28211|Alphaproteobacteria,2K44Z@204457|Sphingomonadales	204457|Sphingomonadales	S	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
SRD2_k127_6708918_2	279238.Saro_1696	4.015e-206	649.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2TQM7@28211|Alphaproteobacteria,2K0K7@204457|Sphingomonadales	204457|Sphingomonadales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRD2_k127_6708918_17	13689.BV96_03392	3.089e-64	224.0	COG3814@1|root,COG3814@2|Bacteria,1N1FE@1224|Proteobacteria,2U7H9@28211|Alphaproteobacteria,2K35H@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09985	-	-	-	-	ko00000	-	-	-	SspB
SRD2_k127_6708918_18	745310.G432_10445	5.559e-62	215.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2U956@28211|Alphaproteobacteria,2K4G2@204457|Sphingomonadales	204457|Sphingomonadales	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	HIT
SRD2_k127_6708918_1	1292034.OR37_02259	2.932e-259	809.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TRNX@28211|Alphaproteobacteria,2KEXX@204458|Caulobacterales	204458|Caulobacterales	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRD2_k127_6708918_24	322710.Avin_29360	2.798e-18	92.0	COG0346@1|root,COG0346@2|Bacteria,1RHD4@1224|Proteobacteria,1S67S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD2_k127_6708918_7	1545915.JROG01000004_gene2391	1.346e-121	398.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,2K0DX@204457|Sphingomonadales	204457|Sphingomonadales	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRD2_k127_6708918_23	1219049.SP5_038_00070	8.822e-19	91.0	2EHHR@1|root,33B9P@2|Bacteria,1NGHW@1224|Proteobacteria,2UJVS@28211|Alphaproteobacteria,2K6SJ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6708918_3	13690.CP98_04391	9.691e-152	486.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2TR5E@28211|Alphaproteobacteria,2K0HW@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
SRD2_k127_6708918_4	1123267.JONN01000001_gene2303	2.016e-141	457.0	COG4152@1|root,COG4152@2|Bacteria,1QUPV@1224|Proteobacteria,2TW40@28211|Alphaproteobacteria,2JZWA@204457|Sphingomonadales	204457|Sphingomonadales	S	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD2_k127_6708918_12	1123267.JONN01000001_gene2302	3.884e-104	359.0	COG1668@1|root,COG1668@2|Bacteria,1MWAS@1224|Proteobacteria,2TU2K@28211|Alphaproteobacteria,2K1E9@204457|Sphingomonadales	204457|Sphingomonadales	CP	ABC-type Na efflux pump, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRD2_k127_6708918_15	1449076.JOOE01000004_gene493	1.284e-82	282.0	COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria,2U3CR@28211|Alphaproteobacteria,2K4EU@204457|Sphingomonadales	204457|Sphingomonadales	G	COG2513 PEP phosphonomutase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRD2_k127_6708918_6	1458357.BG58_13995	1.141e-129	424.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2VIJV@28216|Betaproteobacteria,1K0BS@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRD2_k127_6708918_5	1458357.BG58_13990	1.786e-134	436.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria,1K00C@119060|Burkholderiaceae	28216|Betaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRD2_k127_6708918_11	1246459.KB898357_gene1484	2.598e-104	349.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2TQYQ@28211|Alphaproteobacteria,4BCJY@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	pstA	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRD2_k127_6708918_9	1040986.ATYO01000006_gene306	1.422e-108	359.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2TQX9@28211|Alphaproteobacteria,43J47@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRD2_k127_6708918_10	1123267.JONN01000001_gene1843	2.044e-107	351.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2TQMN@28211|Alphaproteobacteria,2K0AA@204457|Sphingomonadales	204457|Sphingomonadales	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRD2_k127_6708918_8	392499.Swit_3577	1.9e-116	378.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,2K0QB@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD2_k127_6708918_16	1385517.N800_10875	5.705e-70	240.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,1RN5Q@1236|Gammaproteobacteria,1X3FS@135614|Xanthomonadales	135614|Xanthomonadales	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRD2_k127_6739347_2	1282362.AEAC466_10495	7.046e-21	94.0	COG0665@1|root,COG0665@2|Bacteria,1RH7N@1224|Proteobacteria,2U9PJ@28211|Alphaproteobacteria,2KINY@204458|Caulobacterales	204458|Caulobacterales	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6739347_0	1449076.JOOE01000001_gene2874	8.036e-232	734.0	COG5368@1|root,COG5368@2|Bacteria,1NX2K@1224|Proteobacteria,2U1B2@28211|Alphaproteobacteria,2K0T2@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
SRD2_k127_6739347_1	1449076.JOOE01000001_gene2873	3.368e-49	181.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2U199@28211|Alphaproteobacteria,2K1DZ@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRD2_k127_6742928_12	1123267.JONN01000001_gene397	3.151e-135	437.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2TR01@28211|Alphaproteobacteria,2K1JP@204457|Sphingomonadales	204457|Sphingomonadales	O	molecular chaperone	dnaJ_2	-	-	-	-	-	-	-	-	-	-	-	DnaJ,DnaJ_C
SRD2_k127_6742928_13	1123267.JONN01000001_gene398	2.772e-126	412.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,2TTN5@28211|Alphaproteobacteria,2K0UY@204457|Sphingomonadales	204457|Sphingomonadales	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRD2_k127_6742928_8	1123269.NX02_27450	4.264e-145	463.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2TSU4@28211|Alphaproteobacteria,2K0BH@204457|Sphingomonadales	204457|Sphingomonadales	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD2_k127_6742928_27	1219045.BV98_002092	1.15e-16	92.0	COG1254@1|root,COG1254@2|Bacteria,1PU46@1224|Proteobacteria,2UF7Z@28211|Alphaproteobacteria,2K720@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRD2_k127_6742928_3	1123267.JONN01000001_gene404	2.492e-235	732.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2TRKY@28211|Alphaproteobacteria,2K0T7@204457|Sphingomonadales	204457|Sphingomonadales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRD2_k127_6742928_29	1549858.MC45_17960	4.233e-06	60.0	2AF79@1|root,3156A@2|Bacteria,1P9ZW@1224|Proteobacteria,2UWA2@28211|Alphaproteobacteria,2K5Y5@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6742928_2	1123267.JONN01000001_gene406	3.92e-248	776.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria,2K0J0@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRD2_k127_6742928_7	745310.G432_17685	8.042e-164	527.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2TSHT@28211|Alphaproteobacteria,2K0J1@204457|Sphingomonadales	204457|Sphingomonadales	EH	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRD2_k127_6742928_14	1123267.JONN01000001_gene408	1.558e-106	356.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,2K148@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRD2_k127_6742928_26	237727.NAP1_13083	3.699e-42	159.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2UBR8@28211|Alphaproteobacteria,2K54P@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the HesB IscA family	erpA	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
SRD2_k127_6742928_10	1123267.JONN01000001_gene410	3.309e-143	456.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2TR5J@28211|Alphaproteobacteria,2K0HF@204457|Sphingomonadales	204457|Sphingomonadales	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRD2_k127_6742928_6	1123267.JONN01000001_gene411	4.669e-171	544.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,2TUU2@28211|Alphaproteobacteria,2K0BS@204457|Sphingomonadales	204457|Sphingomonadales	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6742928_11	1090319.KE386571_gene209	5.811e-136	443.0	COG3239@1|root,COG3239@2|Bacteria,1MVY5@1224|Proteobacteria,2U156@28211|Alphaproteobacteria,2K0CR@204457|Sphingomonadales	204457|Sphingomonadales	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRD2_k127_6742928_19	1090320.KB900605_gene1993	4.523e-68	233.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria,2K4J0@204457|Sphingomonadales	204457|Sphingomonadales	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRD2_k127_6742928_1	1123267.JONN01000001_gene1738	7.102e-301	929.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2TRN0@28211|Alphaproteobacteria,2JZZK@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRD2_k127_6742928_21	1123267.JONN01000001_gene1736	5.107e-59	211.0	COG1376@1|root,COG1376@2|Bacteria,1Q823@1224|Proteobacteria,2TV64@28211|Alphaproteobacteria,2K2JH@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,YkuD
SRD2_k127_6742928_30	392499.Swit_3430	1.191e-05	54.0	COG3798@1|root,COG3798@2|Bacteria,1N0BJ@1224|Proteobacteria,2UDJF@28211|Alphaproteobacteria,2KE5H@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein conserved in bacteria (DUF2171)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2171
SRD2_k127_6742928_15	1007104.SUS17_2016	9.108e-94	325.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,2TUSJ@28211|Alphaproteobacteria,2K1K2@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRD2_k127_6742928_16	1219049.SP5_013_00030	1.865e-88	297.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2TRTZ@28211|Alphaproteobacteria,2K1RM@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD2_k127_6742928_24	1123269.NX02_21010	7.032e-48	181.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2U9GW@28211|Alphaproteobacteria,2K4I1@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRD2_k127_6742928_9	1123267.JONN01000001_gene1719	4.523e-145	465.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2TQT1@28211|Alphaproteobacteria,2K1CJ@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRD2_k127_6742928_23	1114964.L485_15780	2.131e-52	194.0	COG4649@1|root,COG4649@2|Bacteria,1P2GI@1224|Proteobacteria,2UCFZ@28211|Alphaproteobacteria,2K40C@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
SRD2_k127_6742928_5	1123267.JONN01000001_gene1721	1.744e-171	551.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria,2K0GW@204457|Sphingomonadales	204457|Sphingomonadales	S	Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRD2_k127_6742928_4	1123267.JONN01000001_gene1722	9.963e-224	700.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2TT38@28211|Alphaproteobacteria,2K0SQ@204457|Sphingomonadales	204457|Sphingomonadales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRD2_k127_6742928_20	1123267.JONN01000001_gene1723	2.067e-65	227.0	COG2198@1|root,COG2198@2|Bacteria,1NMJT@1224|Proteobacteria,2UQPF@28211|Alphaproteobacteria,2K588@204457|Sphingomonadales	204457|Sphingomonadales	T	Hpt domain	-	-	-	ko:K20976	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Hpt
SRD2_k127_6742928_18	1123267.JONN01000001_gene1725	3.41e-75	256.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,2U70I@28211|Alphaproteobacteria,2K3XA@204457|Sphingomonadales	204457|Sphingomonadales	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	bfr	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRD2_k127_6742928_28	627192.SLG_23210	4.836e-14	73.0	COG2906@1|root,COG2906@2|Bacteria,1NI9P@1224|Proteobacteria,2UKEU@28211|Alphaproteobacteria,2KDRJ@204457|Sphingomonadales	204457|Sphingomonadales	P	BFD-like [2Fe-2S] binding domain	-	-	-	ko:K02192	-	-	-	-	ko00000	-	-	-	Fer2_BFD
SRD2_k127_6742928_25	1545915.JROG01000001_gene136	6.477e-46	169.0	2DMMQ@1|root,32SHK@2|Bacteria,1N2WS@1224|Proteobacteria,2UC62@28211|Alphaproteobacteria,2K5BZ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
SRD2_k127_6742928_0	1123267.JONN01000001_gene433	0.0	1162.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,2TRGM@28211|Alphaproteobacteria,2K25A@204457|Sphingomonadales	204457|Sphingomonadales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRD2_k127_6742928_22	745310.G432_05620	2.141e-58	208.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,2U922@28211|Alphaproteobacteria,2K6UN@204457|Sphingomonadales	204457|Sphingomonadales	S	Glyoxalase-like domain	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRD2_k127_6742928_17	1248916.ANFY01000017_gene1427	1.358e-78	277.0	COG1680@1|root,COG1680@2|Bacteria,1R8N7@1224|Proteobacteria,2UCNR@28211|Alphaproteobacteria,2K0VY@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRD2_k127_6758690_11	1123267.JONN01000001_gene2271	1.094e-81	284.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1MXFM@1224|Proteobacteria,2TWYV@28211|Alphaproteobacteria,2K14T@204457|Sphingomonadales	204457|Sphingomonadales	H	Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRD2_k127_6758690_12	1304275.C41B8_00915	1.834e-80	286.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST,RimK
SRD2_k127_6758690_22	314278.NB231_15833	8.169e-49	189.0	COG4424@1|root,COG4424@2|Bacteria,1RGI6@1224|Proteobacteria,1S85X@1236|Gammaproteobacteria,1X13Z@135613|Chromatiales	135613|Chromatiales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRD2_k127_6758690_20	1219045.BV98_000255	2.014e-55	209.0	COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRD2_k127_6758690_0	1088721.NSU_0816	1.686e-194	626.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRD2_k127_6758690_7	1123270.ATUR01000002_gene2557	1.348e-133	436.0	COG1887@1|root,COG1887@2|Bacteria,1RCSC@1224|Proteobacteria,2U6GW@28211|Alphaproteobacteria,2K97N@204457|Sphingomonadales	204457|Sphingomonadales	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
SRD2_k127_6758690_5	1030157.AFMP01000014_gene3433	9.168e-149	482.0	COG1887@1|root,COG1887@2|Bacteria,1R4MQ@1224|Proteobacteria,2U1UT@28211|Alphaproteobacteria,2K2VK@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6758690_16	1449049.JONW01000007_gene4140	4.058e-67	241.0	COG0223@1|root,COG0223@2|Bacteria,1NN5V@1224|Proteobacteria,2TTHZ@28211|Alphaproteobacteria,2KHUD@204458|Caulobacterales	204458|Caulobacterales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6758690_18	261292.Nit79A3_1526	3.09e-56	210.0	COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,2VQCX@28216|Betaproteobacteria,372VR@32003|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRD2_k127_6758690_10	685778.AORL01000013_gene1980	2.799e-105	356.0	COG2244@1|root,COG2244@2|Bacteria,1RDQG@1224|Proteobacteria,2U6PC@28211|Alphaproteobacteria,2K0Q9@204457|Sphingomonadales	204457|Sphingomonadales	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SRD2_k127_6758690_1	1549858.MC45_17695	1.285e-191	616.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2K395@204457|Sphingomonadales	204457|Sphingomonadales	E	Glutamine amidotransferase domain	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRD2_k127_6758690_24	670292.JH26_18565	4.534e-27	117.0	COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2TQWR@28211|Alphaproteobacteria,1JWK4@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRD2_k127_6758690_17	1123267.JONN01000002_gene188	8.281e-66	226.0	COG0745@1|root,COG0745@2|Bacteria,1QUSA@1224|Proteobacteria,2TW5G@28211|Alphaproteobacteria,2K5A5@204457|Sphingomonadales	204457|Sphingomonadales	T	response regulator	-	-	-	ko:K13589	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRD2_k127_6758690_13	1123267.JONN01000002_gene187	3.213e-74	259.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2TUPZ@28211|Alphaproteobacteria,2K41R@204457|Sphingomonadales	204457|Sphingomonadales	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
SRD2_k127_6758690_9	1123267.JONN01000002_gene186	5.249e-113	372.0	2D4T1@1|root,32THI@2|Bacteria,1N892@1224|Proteobacteria,2TWF7@28211|Alphaproteobacteria,2KEER@204457|Sphingomonadales	204457|Sphingomonadales	S	PFAM SapC family protein	-	-	-	-	-	-	-	-	-	-	-	-	SapC
SRD2_k127_6758690_23	1123267.JONN01000002_gene185	6.109e-39	153.0	2AM8F@1|root,31C39@2|Bacteria,1N008@1224|Proteobacteria,2UCNF@28211|Alphaproteobacteria,2K748@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6758690_2	1123267.JONN01000002_gene184	1.449e-189	601.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,2K0CY@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the DEAD box helicase family	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRD2_k127_6758690_6	1380391.JIAS01000001_gene2713	2.698e-143	460.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTDF@28211|Alphaproteobacteria,2JQ9R@204441|Rhodospirillales	204441|Rhodospirillales	O	Glutathione S-transferase, C-terminal domain	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N
SRD2_k127_6758690_3	1123267.JONN01000002_gene179	7.64e-185	589.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2TR87@28211|Alphaproteobacteria,2K0II@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRD2_k127_6758690_19	314278.NB231_15833	1.618e-55	211.0	COG4424@1|root,COG4424@2|Bacteria,1RGI6@1224|Proteobacteria,1S85X@1236|Gammaproteobacteria,1X13Z@135613|Chromatiales	135613|Chromatiales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRD2_k127_6758690_4	392499.Swit_0025	2.238e-163	520.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2TS0D@28211|Alphaproteobacteria,2K0G0@204457|Sphingomonadales	204457|Sphingomonadales	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRD2_k127_6758690_14	1123267.JONN01000002_gene169	1.544e-72	250.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2U591@28211|Alphaproteobacteria,2KCVY@204457|Sphingomonadales	204457|Sphingomonadales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
SRD2_k127_6758690_15	1123267.JONN01000002_gene168	5.809e-72	249.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2U74H@28211|Alphaproteobacteria,2K1RJ@204457|Sphingomonadales	204457|Sphingomonadales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRD2_k127_6758690_8	1123267.JONN01000002_gene167	9.297e-129	417.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2TR79@28211|Alphaproteobacteria,2K19H@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRD2_k127_6784360_1	1335760.ASTG01000001_gene3101	1.638e-73	250.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2TRCS@28211|Alphaproteobacteria,2K20W@204457|Sphingomonadales	204457|Sphingomonadales	S	metalloprotease	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRD2_k127_6784360_0	1123267.JONN01000001_gene770	4.294e-145	466.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2TQYM@28211|Alphaproteobacteria,2K21X@204457|Sphingomonadales	204457|Sphingomonadales	L	alcohol dehydrogenase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
SRD2_k127_6784360_2	1123267.JONN01000001_gene771	1.026e-49	191.0	COG3798@1|root,COG3798@2|Bacteria,1N0BJ@1224|Proteobacteria,2UDJF@28211|Alphaproteobacteria,2KE5H@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein conserved in bacteria (DUF2171)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2171
SRD2_k127_6873377_0	1123267.JONN01000001_gene1700	9.619e-271	843.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2TS3Y@28211|Alphaproteobacteria,2K0G5@204457|Sphingomonadales	204457|Sphingomonadales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1,tRNA-synt_1d,tRNA-synt_1f
SRD2_k127_6873377_23	983920.Y88_0500	9.285e-10	67.0	2AKMS@1|root,31BE8@2|Bacteria,1Q78Z@1224|Proteobacteria,2VDDN@28211|Alphaproteobacteria,2K603@204457|Sphingomonadales	204457|Sphingomonadales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
SRD2_k127_6873377_13	1123267.JONN01000001_gene454	3.436e-128	415.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2TRCD@28211|Alphaproteobacteria,2K0JG@204457|Sphingomonadales	204457|Sphingomonadales	F	dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRD2_k127_6873377_19	1123267.JONN01000001_gene454	1.088e-38	147.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2TRCD@28211|Alphaproteobacteria,2K0JG@204457|Sphingomonadales	204457|Sphingomonadales	F	dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRD2_k127_6873377_18	1123267.JONN01000001_gene453	4.153e-63	237.0	COG0457@1|root,COG5010@1|root,COG0457@2|Bacteria,COG5010@2|Bacteria,1RDU3@1224|Proteobacteria,2U790@28211|Alphaproteobacteria,2KEAN@204457|Sphingomonadales	204457|Sphingomonadales	U	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_19
SRD2_k127_6873377_3	1123267.JONN01000001_gene452	1.067e-216	679.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2TS1Q@28211|Alphaproteobacteria,2K16V@204457|Sphingomonadales	204457|Sphingomonadales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRD2_k127_6873377_21	401053.AciPR4_0635	1.047e-24	107.0	2C1V4@1|root,33ZNF@2|Bacteria,3Y87U@57723|Acidobacteria,2JN8M@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6873377_22	1470591.BW41_02401	6.356e-23	100.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,2K5Z5@204457|Sphingomonadales	204457|Sphingomonadales	K	Cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRD2_k127_6873377_16	935840.JAEQ01000012_gene1653	1.645e-92	313.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,2TTMB@28211|Alphaproteobacteria,43IDH@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase	Echdc	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD2_k127_6873377_8	279238.Saro_2348	2.785e-163	528.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,2K0AI@204457|Sphingomonadales	204457|Sphingomonadales	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRD2_k127_6873377_14	1502850.FG91_01127	7.162e-118	394.0	COG2271@1|root,COG2271@2|Bacteria,1MVPS@1224|Proteobacteria,2UD2N@28211|Alphaproteobacteria,2KCXQ@204457|Sphingomonadales	204457|Sphingomonadales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD2_k127_6873377_6	1123267.JONN01000001_gene451	6.864e-190	601.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2TQZB@28211|Alphaproteobacteria,2K082@204457|Sphingomonadales	204457|Sphingomonadales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRD2_k127_6873377_15	1123267.JONN01000001_gene450	1.689e-95	329.0	COG1589@1|root,COG1589@2|Bacteria,1MY1Q@1224|Proteobacteria,2TQPU@28211|Alphaproteobacteria,2K1JE@204457|Sphingomonadales	204457|Sphingomonadales	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRD2_k127_6873377_10	1123267.JONN01000001_gene449	2.126e-157	502.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2TREC@28211|Alphaproteobacteria,2K0W3@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRD2_k127_6873377_12	46429.BV95_00362	6.46e-141	454.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2TRQR@28211|Alphaproteobacteria,2K0QA@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRD2_k127_6873377_2	1123267.JONN01000001_gene447	1.151e-232	739.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2TRT0@28211|Alphaproteobacteria,2K03S@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRD2_k127_6873377_9	1123267.JONN01000001_gene446	2.256e-162	533.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2TSEY@28211|Alphaproteobacteria,2K0YF@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRD2_k127_6873377_7	1123267.JONN01000001_gene445	9.372e-186	592.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2TQSA@28211|Alphaproteobacteria,2K0IS@204457|Sphingomonadales	204457|Sphingomonadales	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRD2_k127_6873377_11	452662.SJA_C1-27950	4.318e-155	512.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2TTE8@28211|Alphaproteobacteria,2K1GM@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRD2_k127_6873377_5	1123267.JONN01000001_gene442	4.258e-190	604.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2TR0Q@28211|Alphaproteobacteria,2K1N2@204457|Sphingomonadales	204457|Sphingomonadales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRD2_k127_6873377_4	1123267.JONN01000001_gene441	2.683e-215	676.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2TVXI@28211|Alphaproteobacteria,2K12F@204457|Sphingomonadales	204457|Sphingomonadales	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRD2_k127_6873377_1	1123267.JONN01000001_gene440	1.112e-242	764.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2TSHQ@28211|Alphaproteobacteria,2K0Y2@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell division protein FtsI penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRD2_k127_6873377_20	1123267.JONN01000001_gene439	9.232e-32	136.0	2AK00@1|root,31APD@2|Bacteria,1NHHT@1224|Proteobacteria,2UM7C@28211|Alphaproteobacteria,2K3BJ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_6873377_17	1123267.JONN01000001_gene438	2.993e-90	301.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2TRQA@28211|Alphaproteobacteria,2K178@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRD2_k127_696347_0	1123267.JONN01000001_gene1398	0.0	1087.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,2K2HN@204457|Sphingomonadales	204457|Sphingomonadales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
SRD2_k127_696347_4	1123267.JONN01000001_gene1400	1.77e-68	252.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2U7BZ@28211|Alphaproteobacteria,2K0BP@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRD2_k127_696347_3	1123267.JONN01000001_gene1401	9.432e-104	344.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2TSR7@28211|Alphaproteobacteria,2K1X9@204457|Sphingomonadales	204457|Sphingomonadales	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRD2_k127_696347_2	1123267.JONN01000001_gene1402	2.512e-217	678.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQXI@28211|Alphaproteobacteria,2K08Q@204457|Sphingomonadales	204457|Sphingomonadales	E	5-aminolevulinic acid synthase	hemA	-	2.3.1.37	ko:K00643	ko00260,ko00860,ko01100,ko01110,map00260,map00860,map01100,map01110	-	R00830	RC00004,RC02815	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRD2_k127_696347_8	570967.JMLV01000001_gene2799	8.008e-36	148.0	2DG8R@1|root,2ZUYV@2|Bacteria,1R8VA@1224|Proteobacteria,2VGKJ@28211|Alphaproteobacteria,2JZ9B@204441|Rhodospirillales	204441|Rhodospirillales	H	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
SRD2_k127_696347_6	1123267.JONN01000001_gene1405	1.684e-63	220.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,2U94R@28211|Alphaproteobacteria,2K4KN@204457|Sphingomonadales	204457|Sphingomonadales	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRD2_k127_696347_1	1123267.JONN01000001_gene1406	1.175e-250	779.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2TQKT@28211|Alphaproteobacteria,2K0BB@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRD2_k127_696347_5	745310.G432_04095	2.991e-68	235.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2U75W@28211|Alphaproteobacteria,2K3W4@204457|Sphingomonadales	204457|Sphingomonadales	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRD2_k127_696347_7	1123267.JONN01000001_gene1408	1.318e-46	170.0	COG0565@1|root,COG2827@1|root,COG0565@2|Bacteria,COG2827@2|Bacteria,1N47Y@1224|Proteobacteria,2TS8J@28211|Alphaproteobacteria,2JZUG@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GIY-YIG,SpoU_methylase
SRD2_k127_6976090_4	760117.JN27_15615	2.349e-108	356.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2VIQZ@28216|Betaproteobacteria,473AN@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
SRD2_k127_6976090_5	1346791.M529_04230	4.453e-106	352.0	COG1462@1|root,COG1462@2|Bacteria,1QURH@1224|Proteobacteria,2U2ZX@28211|Alphaproteobacteria,2K2HF@204457|Sphingomonadales	204457|Sphingomonadales	M	protein involved in formation of curli polymers	-	-	-	-	-	-	-	-	-	-	-	-	CsgG,SH3_3
SRD2_k127_6976090_2	1123073.KB899241_gene2940	4.858e-189	603.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN9J@1236|Gammaproteobacteria,1X3AX@135614|Xanthomonadales	135614|Xanthomonadales	M	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRD2_k127_6976090_3	1163409.UUA_06112	8.402e-119	392.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RWJY@1236|Gammaproteobacteria,1X3Z5@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
SRD2_k127_6976090_0	1234364.AMSF01000058_gene936	0.0	1518.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1RSMT@1236|Gammaproteobacteria,1X5DQ@135614|Xanthomonadales	135614|Xanthomonadales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
SRD2_k127_6976090_1	745310.G432_09235	0.0	1031.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,2K17X@204457|Sphingomonadales	204457|Sphingomonadales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRD2_k127_7011506_19	1112216.JH594426_gene3695	3.043e-62	218.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,2TRNM@28211|Alphaproteobacteria,2K3P4@204457|Sphingomonadales	204457|Sphingomonadales	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
SRD2_k127_7011506_24	13689.BV96_00449	6.489e-49	180.0	COG5478@1|root,COG5478@2|Bacteria,1MZMZ@1224|Proteobacteria,2UBR2@28211|Alphaproteobacteria,2K5A3@204457|Sphingomonadales	204457|Sphingomonadales	S	small integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Iron_permease
SRD2_k127_7011506_29	1449076.JOOE01000004_gene339	1.728e-07	54.0	2BF46@1|root,328WD@2|Bacteria,1P8AF@1224|Proteobacteria,2UZ3D@28211|Alphaproteobacteria,2K84J@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7011506_18	1248760.ANFZ01000009_gene1135	2e-65	229.0	COG3577@1|root,COG3577@2|Bacteria,1R74B@1224|Proteobacteria,2U3DP@28211|Alphaproteobacteria,2KD6X@204457|Sphingomonadales	204457|Sphingomonadales	S	gag-polyprotein putative aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
SRD2_k127_7011506_30	1194972.MVAC_28758	1.894e-06	53.0	COG1309@1|root,COG1309@2|Bacteria,2ID67@201174|Actinobacteria,23947@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRD2_k127_7011506_6	1449076.JOOE01000001_gene2626	3.769e-156	499.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2TR5I@28211|Alphaproteobacteria,2K1GJ@204457|Sphingomonadales	204457|Sphingomonadales	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
SRD2_k127_7011506_11	1123267.JONN01000001_gene1473	2.97e-115	379.0	COG0702@1|root,COG0702@2|Bacteria,1RCCP@1224|Proteobacteria,2TU1D@28211|Alphaproteobacteria,2K0TF@204457|Sphingomonadales	204457|Sphingomonadales	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRD2_k127_7011506_26	685778.AORL01000010_gene2832	8.289e-31	123.0	COG0236@1|root,COG0236@2|Bacteria,1NHQD@1224|Proteobacteria,2UGSG@28211|Alphaproteobacteria,2K5YB@204457|Sphingomonadales	204457|Sphingomonadales	IQ	acyl carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
SRD2_k127_7011506_3	1502850.FG91_01928	4.325e-223	695.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQYP@28211|Alphaproteobacteria,2K0V8@204457|Sphingomonadales	204457|Sphingomonadales	E	COG0156 7-keto-8-aminopelargonate synthetase and related enzymes	-	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRD2_k127_7011506_5	745310.G432_04460	6.047e-183	593.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2K01C@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,Response_reg
SRD2_k127_7011506_21	1522072.IL54_0018	6.312e-57	211.0	COG3153@1|root,COG3153@2|Bacteria,1QURI@1224|Proteobacteria,2TSFI@28211|Alphaproteobacteria,2KEAP@204457|Sphingomonadales	204457|Sphingomonadales	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7011506_10	1123267.JONN01000001_gene424	9.922e-118	391.0	COG1597@1|root,COG1597@2|Bacteria,1R78V@1224|Proteobacteria,2U0V0@28211|Alphaproteobacteria,2K03G@204457|Sphingomonadales	204457|Sphingomonadales	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRD2_k127_7011506_7	1123267.JONN01000001_gene423	1.278e-153	496.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2U55Q@28211|Alphaproteobacteria,2K07C@204457|Sphingomonadales	204457|Sphingomonadales	S	YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
SRD2_k127_7011506_8	1123267.JONN01000001_gene422	3.154e-128	436.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2TR76@28211|Alphaproteobacteria,2K1ZM@204457|Sphingomonadales	204457|Sphingomonadales	S	YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
SRD2_k127_7011506_1	685778.AORL01000015_gene2454	0.0	1220.0	COG3537@1|root,COG3537@2|Bacteria,1MXCY@1224|Proteobacteria,2U396@28211|Alphaproteobacteria,2K1RC@204457|Sphingomonadales	28211|Alphaproteobacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
SRD2_k127_7011506_4	1123267.JONN01000001_gene1754	1.091e-195	614.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2TSI0@28211|Alphaproteobacteria,2K0R2@204457|Sphingomonadales	204457|Sphingomonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRD2_k127_7011506_17	685778.AORL01000010_gene2761	7.607e-68	231.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2U717@28211|Alphaproteobacteria,2K3VT@204457|Sphingomonadales	204457|Sphingomonadales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRD2_k127_7011506_20	1123267.JONN01000001_gene1752	3.755e-61	212.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2U73D@28211|Alphaproteobacteria,2K4E3@204457|Sphingomonadales	204457|Sphingomonadales	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRD2_k127_7011506_23	1320556.AVBP01000001_gene4425	7.271e-55	198.0	COG4331@1|root,COG4331@2|Bacteria,1RGSA@1224|Proteobacteria,2U713@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Predicted membrane protein (DUF2127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2127
SRD2_k127_7011506_12	279238.Saro_3260	3.009e-107	356.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2TTUY@28211|Alphaproteobacteria,2K0M2@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRD2_k127_7011506_0	1174684.EBMC1_03909	0.0	1437.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2TR3N@28211|Alphaproteobacteria,2K0GR@204457|Sphingomonadales	204457|Sphingomonadales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
SRD2_k127_7011506_22	194867.ALBQ01000017_gene2386	6.944e-56	201.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2UBUC@28211|Alphaproteobacteria,2K4K3@204457|Sphingomonadales	204457|Sphingomonadales	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRD2_k127_7011506_25	1123267.JONN01000001_gene1748	1.47e-33	134.0	2C068@1|root,30N9J@2|Bacteria,1RG08@1224|Proteobacteria,2U9FG@28211|Alphaproteobacteria,2K56D@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3035)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3035
SRD2_k127_7011506_15	1123267.JONN01000001_gene1747	5.83e-82	276.0	COG0745@1|root,COG0745@2|Bacteria	1123267.JONN01000001_gene1747|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7011506_13	1123267.JONN01000001_gene1745	4.26e-100	335.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2TR9R@28211|Alphaproteobacteria,2K1GF@204457|Sphingomonadales	204457|Sphingomonadales	P	Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRD2_k127_7011506_9	745310.G432_17370	4.973e-118	385.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,2U1VI@28211|Alphaproteobacteria,2K0CQ@204457|Sphingomonadales	204457|Sphingomonadales	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRD2_k127_7011506_14	1123267.JONN01000001_gene1744	2.562e-83	277.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2U57X@28211|Alphaproteobacteria,2K3W2@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
SRD2_k127_7011506_16	243160.BMA2264	2.232e-74	263.0	COG1893@1|root,COG1893@2|Bacteria,1N0M5@1224|Proteobacteria,2VMSA@28216|Betaproteobacteria,1K55B@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRD2_k127_7011506_2	1123267.JONN01000001_gene1743	5.417e-273	856.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,2TRCZ@28211|Alphaproteobacteria,2K1RU@204457|Sphingomonadales	204457|Sphingomonadales	S	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SRD2_k127_7011506_31	452863.Achl_0896	0.0009972	48.0	COG0328@1|root,COG4994@1|root,COG0328@2|Bacteria,COG4994@2|Bacteria,2GK53@201174|Actinobacteria,1W8WY@1268|Micrococcaceae	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF4440,RNase_H
SRD2_k127_7048927_2	1185876.BN8_04092	1e-71	248.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFTM@976|Bacteroidetes,47NS1@768503|Cytophagia	976|Bacteroidetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
SRD2_k127_7048927_1	1123267.JONN01000001_gene2461	1.551e-311	966.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,2K050@204457|Sphingomonadales	204457|Sphingomonadales	I	acetyl propionyl-CoA carboxylase, alpha subunit	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRD2_k127_7048927_0	1123267.JONN01000001_gene2460	0.0	1146.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,2K0E7@204457|Sphingomonadales	204457|Sphingomonadales	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRD2_k127_7048927_4	158500.BV97_04496	1.971e-45	177.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2TS0V@28211|Alphaproteobacteria,2KEFP@204457|Sphingomonadales	204457|Sphingomonadales	CO	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD
SRD2_k127_7048927_3	1123267.JONN01000001_gene1607	2.123e-61	215.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,2K4P6@204457|Sphingomonadales	204457|Sphingomonadales	O	conserved domain frequently associated with peptide methionine sulfoxide reductase	-	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRD2_k127_7059992_6	1123267.JONN01000002_gene354	3.053e-106	358.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2TSAC@28211|Alphaproteobacteria,2K030@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD2_k127_7059992_1	1123267.JONN01000002_gene355	1.539e-197	638.0	COG1629@1|root,COG4771@2|Bacteria,1R0WC@1224|Proteobacteria,2U1A6@28211|Alphaproteobacteria,2KE9F@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRD2_k127_7059992_12	1123267.JONN01000001_gene728	1.119e-58	215.0	COG4219@1|root,COG4219@2|Bacteria,1P0K4@1224|Proteobacteria,2UVBF@28211|Alphaproteobacteria,2K7R8@204457|Sphingomonadales	204457|Sphingomonadales	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7059992_3	1123267.JONN01000001_gene729	1.414e-129	436.0	COG4219@1|root,COG4219@2|Bacteria,1N96C@1224|Proteobacteria,2UI6V@28211|Alphaproteobacteria,2K34J@204457|Sphingomonadales	204457|Sphingomonadales	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
SRD2_k127_7059992_13	1123267.JONN01000001_gene730	3.165e-48	175.0	COG3682@1|root,COG3682@2|Bacteria,1N95N@1224|Proteobacteria,2UISP@28211|Alphaproteobacteria,2K5C7@204457|Sphingomonadales	204457|Sphingomonadales	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRD2_k127_7059992_16	1125973.JNLC01000004_gene3050	6.305e-07	55.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TSGZ@28211|Alphaproteobacteria,3JUDN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRD2_k127_7059992_14	1168059.KB899087_gene1061	1.131e-11	66.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRD2_k127_7059992_4	1123267.JONN01000002_gene356	1.084e-120	397.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,2TRP0@28211|Alphaproteobacteria,2K0TV@204457|Sphingomonadales	204457|Sphingomonadales	M	Lytic murein transglycosylase	mltB	-	-	-	-	-	-	-	-	-	-	-	SLT_2
SRD2_k127_7059992_2	1123267.JONN01000002_gene357	3.411e-172	550.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TS1P@28211|Alphaproteobacteria,2K17Y@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the peptidase S11 family	dac	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
SRD2_k127_7059992_9	1123267.JONN01000002_gene358	2.592e-89	299.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2U72D@28211|Alphaproteobacteria,2K3VU@204457|Sphingomonadales	204457|Sphingomonadales	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRD2_k127_7059992_7	1123267.JONN01000002_gene359	1.584e-104	351.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2TV3E@28211|Alphaproteobacteria,2JZZA@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
SRD2_k127_7059992_0	1545915.JROG01000003_gene958	1.543e-243	761.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2TQKA@28211|Alphaproteobacteria,2K0VF@204457|Sphingomonadales	204457|Sphingomonadales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRD2_k127_7059992_5	1123267.JONN01000002_gene361	1.866e-116	387.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2TS88@28211|Alphaproteobacteria,2K0X6@204457|Sphingomonadales	204457|Sphingomonadales	L	LuxR family transcriptional regulator	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRD2_k127_7059992_8	1123267.JONN01000002_gene362	1.45e-98	327.0	COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,2TQQN@28211|Alphaproteobacteria,2K1KQ@204457|Sphingomonadales	204457|Sphingomonadales	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
SRD2_k127_7059992_11	1123267.JONN01000002_gene364	4.921e-69	239.0	COG3577@1|root,COG3577@2|Bacteria,1R74B@1224|Proteobacteria,2UBEE@28211|Alphaproteobacteria,2K1P8@204457|Sphingomonadales	204457|Sphingomonadales	S	gag-polyprotein putative aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
SRD2_k127_7059992_10	1123267.JONN01000002_gene365	2.209e-85	287.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,2K0DA@204457|Sphingomonadales	204457|Sphingomonadales	S	MazG family	mazG	-	3.6.1.9	ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
SRD2_k127_7101084_4	1185876.BN8_04092	2.365e-45	181.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFTM@976|Bacteroidetes,47NS1@768503|Cytophagia	976|Bacteroidetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
SRD2_k127_7101084_0	1123269.NX02_26340	0.0	1058.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2K05M@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRD2_k127_7101084_1	1123267.JONN01000001_gene2299	2.918e-136	445.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2TRSV@28211|Alphaproteobacteria,2K0ZI@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
SRD2_k127_7101084_2	1054213.HMPREF9946_04529	3.352e-72	248.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2U58D@28211|Alphaproteobacteria,2JRTF@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRD2_k127_7101084_3	1123267.JONN01000001_gene2301	3.365e-54	198.0	COG2199@1|root,COG2199@2|Bacteria,1Q7FU@1224|Proteobacteria,2TRE7@28211|Alphaproteobacteria,2K6NS@204457|Sphingomonadales	204457|Sphingomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRD2_k127_7101084_5	1192759.AKIB01000034_gene3209	6.579e-39	147.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2TSQ0@28211|Alphaproteobacteria,2K06W@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRD2_k127_7267333_21	1219045.BV98_000385	1.578e-59	212.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2TSQ0@28211|Alphaproteobacteria,2K06W@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRD2_k127_7267333_2	1144307.PMI04_02904	3.695e-158	509.0	COG2866@1|root,COG2866@2|Bacteria,1MUMN@1224|Proteobacteria,2TREN@28211|Alphaproteobacteria,2K01Q@204457|Sphingomonadales	204457|Sphingomonadales	E	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRD2_k127_7267333_4	1123267.JONN01000001_gene2316	1.895e-146	471.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,2TTC7@28211|Alphaproteobacteria,2K1G3@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRD2_k127_7267333_16	1123267.JONN01000001_gene1011	9.871e-71	245.0	28JRZ@1|root,2Z9HI@2|Bacteria,1R52Z@1224|Proteobacteria,2U6D6@28211|Alphaproteobacteria,2K3XN@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
SRD2_k127_7267333_22	685778.AORL01000022_gene1306	1.039e-54	198.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2U99Y@28211|Alphaproteobacteria,2K54X@204457|Sphingomonadales	204457|Sphingomonadales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRD2_k127_7267333_29	1123073.KB899242_gene1672	6.303e-19	89.0	COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,1SGV7@1236|Gammaproteobacteria,1X8U9@135614|Xanthomonadales	135614|Xanthomonadales	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRD2_k127_7267333_32	161528.ED21_22698	2.951e-15	79.0	COG0257@1|root,COG0257@2|Bacteria,1NGBJ@1224|Proteobacteria,2UJAG@28211|Alphaproteobacteria,2K7QY@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRD2_k127_7267333_33	264203.ZMO1958	4.093e-12	72.0	2ANHM@1|root,31DGD@2|Bacteria,1PBN5@1224|Proteobacteria,2UX1C@28211|Alphaproteobacteria,2K77Q@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7267333_1	1123267.JONN01000001_gene2322	1.244e-176	565.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2TVIF@28211|Alphaproteobacteria,2K0X5@204457|Sphingomonadales	204457|Sphingomonadales	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
SRD2_k127_7267333_13	1123267.JONN01000001_gene2323	5.224e-108	357.0	COG0652@1|root,COG0652@2|Bacteria,1QCY4@1224|Proteobacteria,2U56N@28211|Alphaproteobacteria,2K25P@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
SRD2_k127_7267333_26	1123267.JONN01000001_gene2324	8.412e-33	132.0	29188@1|root,2ZNVC@2|Bacteria,1NM5D@1224|Proteobacteria,2UMZG@28211|Alphaproteobacteria,2K7SH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7267333_34	1123267.JONN01000001_gene1029	5.971e-10	63.0	2AM82@1|root,31C2W@2|Bacteria,1P3W8@1224|Proteobacteria,2UVCJ@28211|Alphaproteobacteria,2KB9A@204457|Sphingomonadales	204457|Sphingomonadales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
SRD2_k127_7267333_5	1123267.JONN01000001_gene2329	2.116e-145	475.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,2K0KA@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	YkuD
SRD2_k127_7267333_15	1123267.JONN01000001_gene2330	1.406e-76	263.0	COG1376@1|root,COG1376@2|Bacteria,1RKB2@1224|Proteobacteria,2UAA8@28211|Alphaproteobacteria,2K4DR@204457|Sphingomonadales	204457|Sphingomonadales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
SRD2_k127_7267333_27	1123267.JONN01000001_gene2331	1.374e-28	115.0	COG0828@1|root,COG0828@2|Bacteria,1MZA1@1224|Proteobacteria,2UC58@28211|Alphaproteobacteria,2K5X3@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
SRD2_k127_7267333_30	1537715.JQFJ01000002_gene954	2.734e-17	91.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2U9XK@28211|Alphaproteobacteria,2K4Y5@204457|Sphingomonadales	204457|Sphingomonadales	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
SRD2_k127_7267333_11	1123269.NX02_27340	1.538e-113	379.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2TQSH@28211|Alphaproteobacteria,2K0XW@204457|Sphingomonadales	204457|Sphingomonadales	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRD2_k127_7267333_9	1123267.JONN01000001_gene2334	7.609e-126	408.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,2K1V9@204457|Sphingomonadales	204457|Sphingomonadales	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRD2_k127_7267333_20	1096930.L284_10660	4.517e-61	215.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2U77S@28211|Alphaproteobacteria,2K4ID@204457|Sphingomonadales	204457|Sphingomonadales	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRD2_k127_7267333_10	1030157.AFMP01000040_gene1410	7.072e-120	400.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2TTTF@28211|Alphaproteobacteria,2K0T4@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
SRD2_k127_7267333_14	1112212.JH584235_gene1978	1.166e-91	304.0	COG0461@1|root,COG0461@2|Bacteria,1RIC5@1224|Proteobacteria,2TUX2@28211|Alphaproteobacteria,2K1QD@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRD2_k127_7267333_12	1123267.JONN01000001_gene2338	5.209e-108	361.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,2TRK6@28211|Alphaproteobacteria,2K00C@204457|Sphingomonadales	204457|Sphingomonadales	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRD2_k127_7267333_0	1123267.JONN01000001_gene2339	1.489e-317	977.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,2K034@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRD2_k127_7267333_23	983920.Y88_2371	8.002e-53	192.0	COG0652@1|root,COG0652@2|Bacteria,1RGF5@1224|Proteobacteria,2U7DS@28211|Alphaproteobacteria,2KCH6@204457|Sphingomonadales	204457|Sphingomonadales	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRD2_k127_7267333_7	1030157.AFMP01000040_gene1404	3.184e-130	421.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2TRD8@28211|Alphaproteobacteria,2K01V@204457|Sphingomonadales	204457|Sphingomonadales	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRD2_k127_7267333_36	1090318.ATTI01000001_gene3334	9.942e-05	49.0	2BTQ4@1|root,32NX6@2|Bacteria,1PV20@1224|Proteobacteria,2V6IY@28211|Alphaproteobacteria,2K7TE@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7267333_19	1123267.JONN01000001_gene2345	4.432e-62	221.0	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,2U6ZT@28211|Alphaproteobacteria,2K3WU@204457|Sphingomonadales	204457|Sphingomonadales	O	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I	ctaG	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
SRD2_k127_7267333_6	685778.AORL01000022_gene1381	1.756e-140	450.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2TQWA@28211|Alphaproteobacteria,2JZW3@204457|Sphingomonadales	204457|Sphingomonadales	C	Heme copper-type cytochrome quinol oxidase, subunit 3	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRD2_k127_7267333_25	1123267.JONN01000001_gene2347	1.579e-38	151.0	COG5349@1|root,COG5349@2|Bacteria,1N0WU@1224|Proteobacteria,2UCE7@28211|Alphaproteobacteria,2K61Z@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
SRD2_k127_7267333_18	685778.AORL01000022_gene1379	1.349e-63	228.0	COG3346@1|root,COG3346@2|Bacteria,1RIJQ@1224|Proteobacteria,2UA1G@28211|Alphaproteobacteria,2K34C@204457|Sphingomonadales	204457|Sphingomonadales	S	SURF1-like protein	-	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
SRD2_k127_7267333_8	745310.G432_14290	3.829e-126	421.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TR39@28211|Alphaproteobacteria,2K1F2@204457|Sphingomonadales	204457|Sphingomonadales	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRD2_k127_7267333_3	1123267.JONN01000001_gene2350	2.834e-152	489.0	COG1092@1|root,COG1092@2|Bacteria,1QSD4@1224|Proteobacteria,2TUFT@28211|Alphaproteobacteria,2K037@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
SRD2_k127_7267333_17	1123267.JONN01000001_gene2351	1.951e-64	236.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2TUSG@28211|Alphaproteobacteria,2K43Z@204457|Sphingomonadales	204457|Sphingomonadales	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SRD2_k127_7267333_24	1449076.JOOE01000004_gene126	1.415e-51	188.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2TVBT@28211|Alphaproteobacteria,2K5BJ@204457|Sphingomonadales	204457|Sphingomonadales	O	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
SRD2_k127_7267333_35	1121360.AUAQ01000013_gene2237	2.14e-08	55.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,22NFJ@1653|Corynebacteriaceae	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRD2_k127_7282275_1	1123267.JONN01000001_gene1440	4.829e-155	499.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2TRN4@28211|Alphaproteobacteria,2K1GI@204457|Sphingomonadales	204457|Sphingomonadales	E	Glycine cleavage system T protein	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRD2_k127_7282275_3	1123267.JONN01000001_gene1439	5.708e-56	204.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2U9BY@28211|Alphaproteobacteria,2K5E0@204457|Sphingomonadales	204457|Sphingomonadales	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRD2_k127_7282275_2	1123267.JONN01000001_gene1438	1.442e-96	324.0	COG4106@1|root,COG4106@2|Bacteria,1R04W@1224|Proteobacteria,2U5VR@28211|Alphaproteobacteria,2K298@204457|Sphingomonadales	204457|Sphingomonadales	S	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRD2_k127_7282275_0	1123267.JONN01000001_gene1437	3.766e-221	692.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2TR6C@28211|Alphaproteobacteria,2K0IW@204457|Sphingomonadales	204457|Sphingomonadales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRD2_k127_7282275_4	1449076.JOOE01000001_gene2947	2.654e-43	160.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2TSFF@28211|Alphaproteobacteria,2K1GP@204457|Sphingomonadales	204457|Sphingomonadales	E	Glycine dehydrogenase (aminomethyl-transferring)	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRD2_k127_7289170_13	1123267.JONN01000002_gene94	1.985e-106	351.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2TRIM@28211|Alphaproteobacteria,2K1JS@204457|Sphingomonadales	204457|Sphingomonadales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
SRD2_k127_7289170_25	1123267.JONN01000002_gene96	9.686e-48	173.0	COG1725@1|root,COG1725@2|Bacteria,1MZG9@1224|Proteobacteria,2UBQ4@28211|Alphaproteobacteria,2K632@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRD2_k127_7289170_21	1123267.JONN01000002_gene97	5.744e-67	233.0	COG0778@1|root,COG0778@2|Bacteria,1PKUV@1224|Proteobacteria,2U5MZ@28211|Alphaproteobacteria,2K422@204457|Sphingomonadales	204457|Sphingomonadales	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRD2_k127_7289170_1	629773.AORY01000015_gene1342	6.069e-286	890.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,2U15C@28211|Alphaproteobacteria,2K05X@204457|Sphingomonadales	204457|Sphingomonadales	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SRD2_k127_7289170_4	1123267.JONN01000002_gene99	2.323e-221	696.0	COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,2TUMS@28211|Alphaproteobacteria,2K1BD@204457|Sphingomonadales	204457|Sphingomonadales	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRD2_k127_7289170_11	1123267.JONN01000002_gene100	1.101e-164	531.0	COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,2U1V8@28211|Alphaproteobacteria,2K2YY@204457|Sphingomonadales	204457|Sphingomonadales	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRD2_k127_7289170_22	1123267.JONN01000002_gene101	5.738e-61	226.0	COG4094@1|root,COG4094@2|Bacteria,1RDF9@1224|Proteobacteria,2U7NM@28211|Alphaproteobacteria,2K2CX@204457|Sphingomonadales	204457|Sphingomonadales	S	NnrU protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrU
SRD2_k127_7289170_5	1123267.JONN01000002_gene102	1.946e-219	689.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2TQWH@28211|Alphaproteobacteria,2JZV4@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRD2_k127_7289170_9	1123267.JONN01000002_gene103	4.967e-188	594.0	COG0346@1|root,COG0351@1|root,COG0346@2|Bacteria,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2TUKR@28211|Alphaproteobacteria,2K24Q@204457|Sphingomonadales	204457|Sphingomonadales	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase,Phos_pyr_kin
SRD2_k127_7289170_15	1123267.JONN01000001_gene1173	1.056e-91	307.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,2K1EB@204457|Sphingomonadales	204457|Sphingomonadales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRD2_k127_7289170_8	1123267.JONN01000001_gene1174	5.882e-191	602.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TSW9@28211|Alphaproteobacteria,2K0RE@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K13581	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRD2_k127_7289170_12	745310.G432_03235	1.154e-140	455.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2TTMG@28211|Alphaproteobacteria,2K0EE@204457|Sphingomonadales	204457|Sphingomonadales	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRD2_k127_7289170_17	1549858.MC45_13145	3.076e-84	286.0	COG4221@1|root,COG4221@2|Bacteria,1RAAB@1224|Proteobacteria,2U69E@28211|Alphaproteobacteria,2K0MR@204457|Sphingomonadales	204457|Sphingomonadales	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD2_k127_7289170_7	1123267.JONN01000001_gene1177	1.234e-204	647.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2K0T8@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRD2_k127_7289170_10	1030157.AFMP01000036_gene2681	3.043e-168	535.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2TSZN@28211|Alphaproteobacteria,2K062@204457|Sphingomonadales	204457|Sphingomonadales	C	NAD(P) transhydrogenase subunit alpha	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRD2_k127_7289170_16	1461694.ATO9_00105	2.134e-88	305.0	COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria,2TRM2@28211|Alphaproteobacteria,2PDTE@252301|Oceanicola	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
SRD2_k127_7289170_26	663932.KB902575_gene179	5.221e-46	173.0	COG2606@1|root,COG2606@2|Bacteria,1RD82@1224|Proteobacteria,2U7H0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YbaK prolyl-tRNA synthetase associated	MA20_06000	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRD2_k127_7289170_23	1112214.AHIS01000043_gene1844	4.398e-53	190.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,2U945@28211|Alphaproteobacteria,2K4HM@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRD2_k127_7289170_6	1123267.JONN01000002_gene325	3.649e-219	703.0	COG2200@1|root,COG4252@1|root,COG2200@2|Bacteria,COG4252@2|Bacteria,1N299@1224|Proteobacteria,2U5C8@28211|Alphaproteobacteria,2K2WP@204457|Sphingomonadales	204457|Sphingomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,EAL
SRD2_k127_7289170_27	279238.Saro_1844	1.249e-44	163.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,2UBXS@28211|Alphaproteobacteria,2K5AR@204457|Sphingomonadales	204457|Sphingomonadales	C	nad(P) transhydrogenase subunit alpha	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRD2_k127_7289170_3	1449076.JOOE01000003_gene3471	1.726e-239	748.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2TQN1@28211|Alphaproteobacteria,2K05C@204457|Sphingomonadales	204457|Sphingomonadales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRD2_k127_7289170_14	1123267.JONN01000002_gene328	3.36e-93	312.0	COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,2TRKQ@28211|Alphaproteobacteria,2KD7T@204457|Sphingomonadales	204457|Sphingomonadales	M	aspartate racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
SRD2_k127_7289170_0	392499.Swit_4491	0.0	1024.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,2K1TK@204457|Sphingomonadales	204457|Sphingomonadales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
SRD2_k127_7289170_18	46429.BV95_01462	7.373e-83	282.0	COG1381@1|root,COG1381@2|Bacteria,1MVEJ@1224|Proteobacteria,2TTYW@28211|Alphaproteobacteria,2K120@204457|Sphingomonadales	204457|Sphingomonadales	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRD2_k127_7289170_24	1090320.KB900605_gene547	4.573e-53	189.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2U9JM@28211|Alphaproteobacteria,2K4GR@204457|Sphingomonadales	204457|Sphingomonadales	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
SRD2_k127_7289170_19	1112216.JH594425_gene731	9.64e-83	285.0	COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,2U7N2@28211|Alphaproteobacteria,2K1WW@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
SRD2_k127_7289170_20	1123267.JONN01000002_gene232	2.624e-80	276.0	COG1596@1|root,COG1596@2|Bacteria,1RE48@1224|Proteobacteria,2UEIX@28211|Alphaproteobacteria,2KCT0@204457|Sphingomonadales	204457|Sphingomonadales	M	polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRD2_k127_7289170_2	1123267.JONN01000002_gene233	3.379e-242	770.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,2TT1Y@28211|Alphaproteobacteria,2K00D@204457|Sphingomonadales	204457|Sphingomonadales	D	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
SRD2_k127_7292533_2	450851.PHZ_c3511	1.357e-49	187.0	COG2207@1|root,COG2207@2|Bacteria,1MZEA@1224|Proteobacteria,2UDBY@28211|Alphaproteobacteria,2KIZ0@204458|Caulobacterales	204458|Caulobacterales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRD2_k127_7292533_1	983917.RGE_06790	8.805e-62	225.0	2C5JX@1|root,32WNU@2|Bacteria,1NUC9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7292533_3	1223410.KN050846_gene73	8.16e-21	97.0	2EKX6@1|root,33EKQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7292533_0	392499.Swit_3776	1.046e-65	227.0	COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,2TS8Z@28211|Alphaproteobacteria,2K0WB@204457|Sphingomonadales	204457|Sphingomonadales	E	cystathionine beta-lyase	metC	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRD2_k127_7296867_6	1382303.JPOM01000001_gene915	9.796e-78	264.0	COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,2TR62@28211|Alphaproteobacteria,2KFZE@204458|Caulobacterales	204458|Caulobacterales	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRD2_k127_7296867_9	1041147.AUFB01000008_gene836	3.54e-38	147.0	COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria,2UCXT@28211|Alphaproteobacteria,4BFSM@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRD2_k127_7296867_7	1280944.HY17_18505	1.216e-61	219.0	COG0431@1|root,COG0431@2|Bacteria,1RAFI@1224|Proteobacteria,2TUBI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	NAD(P)H-dependent FMN reductase	yieF	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006805,GO:0008150,GO:0008152,GO:0009410,GO:0009987,GO:0010181,GO:0016491,GO:0016645,GO:0016646,GO:0032553,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0052873,GO:0055114,GO:0070887,GO:0071466,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
SRD2_k127_7296867_13	1550073.JROH01000003_gene2395	4.605e-06	53.0	2AM3M@1|root,32HWV@2|Bacteria,1Q8DC@1224|Proteobacteria,2VEJY@28211|Alphaproteobacteria,2K81A@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7296867_0	1549858.MC45_05585	4.749e-310	966.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2TRC1@28211|Alphaproteobacteria,2K0KI@204457|Sphingomonadales	204457|Sphingomonadales	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
SRD2_k127_7296867_10	1247963.JPHU01000020_gene2972	1.625e-37	142.0	COG1734@1|root,COG1734@2|Bacteria,1MZIB@1224|Proteobacteria,2UCQA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG1734 DnaK suppressor protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRD2_k127_7296867_5	1123267.JONN01000001_gene848	6.687e-138	444.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2TSZM@28211|Alphaproteobacteria,2K256@204457|Sphingomonadales	204457|Sphingomonadales	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRD2_k127_7296867_3	1123267.JONN01000001_gene1300	1.212e-190	604.0	COG2234@1|root,COG2234@2|Bacteria,1MWBX@1224|Proteobacteria,2U2RE@28211|Alphaproteobacteria,2JZWX@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRD2_k127_7296867_1	1123267.JONN01000001_gene1301	3.851e-294	908.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2TSMD@28211|Alphaproteobacteria,2K04G@204457|Sphingomonadales	204457|Sphingomonadales	C	Methylmalonate-semialdehyde dehydrogenase	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD2_k127_7296867_11	1088721.NSU_0415	1.279e-16	86.0	2EKD7@1|root,33E3H@2|Bacteria,1NBMH@1224|Proteobacteria,2UG3V@28211|Alphaproteobacteria,2K4NR@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7296867_8	1095769.CAHF01000015_gene2758	2.521e-51	192.0	COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,2VI89@28216|Betaproteobacteria,474HV@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	gst	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N,GST_N_2,GST_N_3
SRD2_k127_7296867_2	1123267.JONN01000001_gene1307	2.994e-212	663.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,2JZVG@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD2_k127_7296867_4	1123267.JONN01000001_gene1308	3.321e-152	494.0	COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,2TQW3@28211|Alphaproteobacteria,2K1J0@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_2
SRD2_k127_7296867_12	194867.ALBQ01000011_gene158	5.273e-12	68.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,2K12I@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD2_k127_7347486_3	383381.EH30_14640	6.981e-19	100.0	COG5388@1|root,COG5388@2|Bacteria,1R74W@1224|Proteobacteria,2TUTW@28211|Alphaproteobacteria,2K1EC@204457|Sphingomonadales	204457|Sphingomonadales	S	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7347486_4	1449076.JOOE01000001_gene1722	8.267e-09	63.0	2AKMS@1|root,31BE8@2|Bacteria,1Q78Z@1224|Proteobacteria,2VDDN@28211|Alphaproteobacteria,2K603@204457|Sphingomonadales	204457|Sphingomonadales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
SRD2_k127_7347486_1	1123267.JONN01000001_gene1358	1.154e-42	166.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2UBY4@28211|Alphaproteobacteria,2K6W9@204457|Sphingomonadales	204457|Sphingomonadales	H	5-formyltetrahydrofolate cyclo-ligase	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SRD2_k127_7347486_2	1123267.JONN01000001_gene1357	5.361e-32	130.0	COG3027@1|root,COG3027@2|Bacteria,1Q3M7@1224|Proteobacteria,2VACI@28211|Alphaproteobacteria,2K78U@204457|Sphingomonadales	204457|Sphingomonadales	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
SRD2_k127_7347486_0	1123267.JONN01000001_gene1355	1.717e-293	912.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2TQUX@28211|Alphaproteobacteria,2K0UZ@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the transketolase family	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRD2_k127_7390430_4	1550073.JROH01000011_gene2073	1.549e-10	65.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,2U6CN@28211|Alphaproteobacteria,2K2DP@204457|Sphingomonadales	204457|Sphingomonadales	KT	Phage shock protein A	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRD2_k127_7390430_3	1123267.JONN01000001_gene685	4.475e-40	150.0	2CC0C@1|root,32ZJ1@2|Bacteria,1R3EF@1224|Proteobacteria,2U01N@28211|Alphaproteobacteria,2KEWT@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3297)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3297
SRD2_k127_7390430_0	1123267.JONN01000001_gene683	2.821e-214	671.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TSEI@28211|Alphaproteobacteria,2K13V@204457|Sphingomonadales	204457|Sphingomonadales	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	E1_dh,OxoDH_E1alpha_N
SRD2_k127_7390430_1	1123267.JONN01000001_gene682	3.305e-188	595.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRFK@28211|Alphaproteobacteria,2K02S@204457|Sphingomonadales	204457|Sphingomonadales	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	bkdA2	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRD2_k127_7390430_2	1123267.JONN01000001_gene681	1.819e-172	550.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2TS31@28211|Alphaproteobacteria,2K1MM@204457|Sphingomonadales	204457|Sphingomonadales	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bkdB	-	2.3.1.168	ko:K09699	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R02662,R03174,R04097,R10998	RC00004,RC02727,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRD2_k127_742877_14	1545915.JROG01000003_gene1156	9.976e-44	171.0	2D5TK@1|root,3133H@2|Bacteria,1NRIX@1224|Proteobacteria,2UQRX@28211|Alphaproteobacteria,2K6JR@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_742877_0	1112212.JH584235_gene308	0.0	1152.0	COG1228@1|root,COG1228@2|Bacteria,1R7TW@1224|Proteobacteria,2VFMX@28211|Alphaproteobacteria,2KDXF@204457|Sphingomonadales	204457|Sphingomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRD2_k127_742877_9	1123267.JONN01000001_gene589	6.477e-91	303.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2TRJR@28211|Alphaproteobacteria,2K3WZ@204457|Sphingomonadales	204457|Sphingomonadales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRD2_k127_742877_10	1123267.JONN01000001_gene591	2.049e-81	281.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2TUVD@28211|Alphaproteobacteria,2K1AR@204457|Sphingomonadales	204457|Sphingomonadales	S	Methanol dehydrogenase	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRD2_k127_742877_13	194867.ALBQ01000017_gene2416	1.718e-51	197.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2U5XG@28211|Alphaproteobacteria,2K470@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRD2_k127_742877_11	1123267.JONN01000001_gene593	1.96e-54	202.0	COG0494@1|root,COG0494@2|Bacteria,1RE72@1224|Proteobacteria,2U805@28211|Alphaproteobacteria,2K4H0@204457|Sphingomonadales	204457|Sphingomonadales	L	Nudix hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRD2_k127_742877_8	1123267.JONN01000001_gene596	7.869e-110	362.0	COG1409@1|root,COG1409@2|Bacteria,1MW6B@1224|Proteobacteria,2U1GX@28211|Alphaproteobacteria,2K28P@204457|Sphingomonadales	204457|Sphingomonadales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRD2_k127_742877_7	1123267.JONN01000001_gene597	2.436e-124	403.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2TS7C@28211|Alphaproteobacteria,2K19F@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the NadC ModD family	-	-	-	-	-	-	-	-	-	-	-	-	QRPTase_C,QRPTase_N
SRD2_k127_742877_4	1123267.JONN01000001_gene599	4.863e-279	861.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,2TV8B@28211|Alphaproteobacteria,2K00A@204457|Sphingomonadales	204457|Sphingomonadales	S	2-nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRD2_k127_742877_12	1123267.JONN01000001_gene600	5.059e-52	191.0	COG3807@1|root,COG3807@2|Bacteria,1RHM2@1224|Proteobacteria,2UA1R@28211|Alphaproteobacteria,2K42W@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
SRD2_k127_742877_16	1192868.CAIU01000008_gene873	1.341e-36	143.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,2UGES@28211|Alphaproteobacteria,43P5X@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRD2_k127_742877_6	1174684.EBMC1_09879	6.017e-182	578.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2K0FQ@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRD2_k127_742877_5	1123267.JONN01000001_gene604	3.5e-213	668.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TREJ@28211|Alphaproteobacteria,2K1PX@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA	-	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD2_k127_742877_1	1123267.JONN01000001_gene606	0.0	1016.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,2TRU4@28211|Alphaproteobacteria,2K1AP@204457|Sphingomonadales	204457|Sphingomonadales	O	Peptidase family M13	-	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
SRD2_k127_742877_2	1081640.AGFU01000021_gene1961	8.064e-297	920.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRA0@28211|Alphaproteobacteria,2K0B0@204457|Sphingomonadales	204457|Sphingomonadales	I	acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRD2_k127_742877_3	1123267.JONN01000001_gene610	7.946e-291	909.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,2K27B@204457|Sphingomonadales	204457|Sphingomonadales	I	acetyl propionyl-CoA carboxylase, alpha subunit	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRD2_k127_742877_15	1282360.ABAC460_00880	2.792e-37	142.0	COG3254@1|root,COG3254@2|Bacteria,1RIRS@1224|Proteobacteria,2UAT0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	rhamnose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRD2_k127_742877_20	426117.M446_0063	0.0006697	45.0	COG0400@1|root,COG0400@2|Bacteria,1P51S@1224|Proteobacteria,2TT0Y@28211|Alphaproteobacteria,1JS9U@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
SRD2_k127_7436804_5	1123269.NX02_00945	6.646e-14	73.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2TR8J@28211|Alphaproteobacteria,2K18B@204457|Sphingomonadales	204457|Sphingomonadales	S	Aminomethyltransferase	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T
SRD2_k127_7436804_2	1144307.PMI04_02379	9.208e-91	307.0	COG1878@1|root,COG1878@2|Bacteria,1R8IH@1224|Proteobacteria,2U9RH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRD2_k127_7436804_4	1335760.ASTG01000006_gene1343	1.819e-24	106.0	2EFVT@1|root,339N0@2|Bacteria,1NJX8@1224|Proteobacteria,2UJ01@28211|Alphaproteobacteria,2K78R@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7436804_0	1123267.JONN01000001_gene2385	0.0	1470.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,2K0CP@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRD2_k127_7436804_1	1123267.JONN01000001_gene2382	1.384e-109	364.0	COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,2TQQD@28211|Alphaproteobacteria,2K4ZK@204457|Sphingomonadales	204457|Sphingomonadales	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRD2_k127_7436804_3	1122218.KB893654_gene2301	1.127e-61	226.0	29CWT@1|root,2ZZUX@2|Bacteria,1REF2@1224|Proteobacteria,2U7K7@28211|Alphaproteobacteria,1JVD1@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2585)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2585
SRD2_k127_7522444_10	1144305.PMI02_04455	9.718e-159	512.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,2TT6S@28211|Alphaproteobacteria,2K14W@204457|Sphingomonadales	204457|Sphingomonadales	G	6-phosphogluconate dehydrogenase	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRD2_k127_7522444_1	1537715.JQFJ01000002_gene1042	0.0	1138.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,2K127@204457|Sphingomonadales	204457|Sphingomonadales	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
SRD2_k127_7522444_25	1449076.JOOE01000001_gene2793	1.082e-05	53.0	2AKT1@1|root,31BK2@2|Bacteria,1NXBB@1224|Proteobacteria,2UTRK@28211|Alphaproteobacteria,2K5KP@204457|Sphingomonadales	204457|Sphingomonadales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
SRD2_k127_7522444_9	685778.AORL01000017_gene3	2.339e-165	539.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,2U1UW@28211|Alphaproteobacteria,2KDB4@204457|Sphingomonadales	204457|Sphingomonadales	S	Alkaline phosphatase with broad substrate specificity	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRD2_k127_7522444_6	450851.PHZ_c0353	8.664e-204	645.0	COG0775@1|root,COG0775@2|Bacteria,1MUMQ@1224|Proteobacteria,2TSX1@28211|Alphaproteobacteria,2KF3S@204458|Caulobacterales	204458|Caulobacterales	F	Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	AMNp_N,PNP_UDP_1
SRD2_k127_7522444_20	1123267.JONN01000002_gene89	7.682e-56	199.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,2U9FW@28211|Alphaproteobacteria,2K4F5@204457|Sphingomonadales	204457|Sphingomonadales	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
SRD2_k127_7522444_0	1090320.KB900605_gene3735	0.0	1317.0	COG3391@1|root,COG3391@2|Bacteria,1R6BZ@1224|Proteobacteria,2U2WX@28211|Alphaproteobacteria,2K3H4@204457|Sphingomonadales	204457|Sphingomonadales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7522444_12	1123267.JONN01000001_gene981	1.69e-151	484.0	COG3491@1|root,COG3491@2|Bacteria,1MUNT@1224|Proteobacteria,2TU3Y@28211|Alphaproteobacteria,2K1Y3@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
SRD2_k127_7522444_24	1219049.SP5_063_00030	2.21e-06	49.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,2TU8A@28211|Alphaproteobacteria,2K07T@204457|Sphingomonadales	204457|Sphingomonadales	F	nucleoside	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
SRD2_k127_7522444_19	1123267.JONN01000001_gene979	5.699e-79	269.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2U5DP@28211|Alphaproteobacteria,2K0TW@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRD2_k127_7522444_15	1123267.JONN01000001_gene978	4.218e-106	353.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,2K0DX@204457|Sphingomonadales	204457|Sphingomonadales	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRD2_k127_7522444_3	1122137.AQXF01000002_gene664	3.222e-211	670.0	COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria	1224|Proteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRD2_k127_7522444_14	1120705.FG95_00723	6.088e-130	424.0	COG3949@1|root,COG3949@2|Bacteria,1QAYU@1224|Proteobacteria,2U6DV@28211|Alphaproteobacteria,2K0X7@204457|Sphingomonadales	204457|Sphingomonadales	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7522444_17	1161401.ASJA01000005_gene2472	1.16e-86	301.0	COG2367@1|root,COG2367@2|Bacteria,1NMW4@1224|Proteobacteria,2VEG4@28211|Alphaproteobacteria,440J3@69657|Hyphomonadaceae	28211|Alphaproteobacteria	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
SRD2_k127_7522444_11	1502850.FG91_00618	2.068e-155	497.0	COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,2TS0Y@28211|Alphaproteobacteria,2K06Y@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
SRD2_k127_7522444_4	1144305.PMI02_02324	1.916e-207	673.0	COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,2U2KS@28211|Alphaproteobacteria,2KDKA@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRD2_k127_7522444_8	1144305.PMI02_02325	1.45e-177	567.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,2U15C@28211|Alphaproteobacteria,2K2WX@204457|Sphingomonadales	204457|Sphingomonadales	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SRD2_k127_7522444_13	1123073.KB899241_gene2160	1.163e-136	443.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,1RMKS@1236|Gammaproteobacteria,1XCGI@135614|Xanthomonadales	135614|Xanthomonadales	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SRD2_k127_7522444_5	517722.AEUE01000003_gene1268	9.547e-206	670.0	COG1680@1|root,COG1680@2|Bacteria,1PQ2Z@1224|Proteobacteria,2U1GN@28211|Alphaproteobacteria,2K210@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRD2_k127_7522444_16	1442599.JAAN01000042_gene3060	1.601e-98	327.0	COG1396@1|root,COG1396@2|Bacteria,1R6PS@1224|Proteobacteria,1T24B@1236|Gammaproteobacteria,1X5S2@135614|Xanthomonadales	135614|Xanthomonadales	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_31
SRD2_k127_7522444_26	1276756.AUEX01000005_gene2823	7.96e-05	53.0	29DIQ@1|root,300GG@2|Bacteria,1RJVY@1224|Proteobacteria,2VTHH@28216|Betaproteobacteria,4AEF9@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
SRD2_k127_7522444_22	314266.SKA58_15357	3.759e-48	184.0	COG0589@1|root,COG0589@2|Bacteria,1QD8E@1224|Proteobacteria,2TRQ7@28211|Alphaproteobacteria,2K4W9@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRD2_k127_7522444_21	450851.PHZ_c0045	4.602e-50	185.0	2A23N@1|root,30QDW@2|Bacteria,1RGGT@1224|Proteobacteria,2U84G@28211|Alphaproteobacteria,2KK6N@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7522444_2	1449076.JOOE01000001_gene2085	6.76e-288	908.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,2K0ZP@204457|Sphingomonadales	204457|Sphingomonadales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.2,3.6.3.6	ko:K01531,ko:K01535	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.3,3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRD2_k127_7522444_7	1114964.L485_18300	9.271e-180	578.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2TS24@28211|Alphaproteobacteria,2K39V@204457|Sphingomonadales	204457|Sphingomonadales	F	Thymidine phosphorylase	-	-	2.4.2.4	ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRD2_k127_7522444_18	1411123.JQNH01000001_gene530	1.691e-85	299.0	COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,2U3AB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Belongs to the ribose-phosphate pyrophosphokinase family	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
SRD2_k127_7528012_4	392499.Swit_1234	5.502e-42	161.0	COG2885@1|root,COG2885@2|Bacteria,1MZKA@1224|Proteobacteria,2UG8A@28211|Alphaproteobacteria,2K64M@204457|Sphingomonadales	204457|Sphingomonadales	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRD2_k127_7528012_1	1502850.FG91_02410	1.324e-138	454.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TQVP@28211|Alphaproteobacteria,2K023@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRD2_k127_7528012_5	161528.ED21_25988	2.536e-28	131.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1N7YB@1224|Proteobacteria,2V7CZ@28211|Alphaproteobacteria,2K2SU@204457|Sphingomonadales	204457|Sphingomonadales	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRD2_k127_7528012_6	1346791.M529_07040	1.834e-22	112.0	COG3710@1|root,COG3710@2|Bacteria,1NAF2@1224|Proteobacteria,2UF4Q@28211|Alphaproteobacteria,2K4BP@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRD2_k127_7528012_3	1123269.NX02_09315	2.635e-49	187.0	COG0589@1|root,COG0589@2|Bacteria,1QD8E@1224|Proteobacteria,2TRQ7@28211|Alphaproteobacteria,2K4W9@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRD2_k127_7528012_2	13689.BV96_03441	4.917e-82	281.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2TT6M@28211|Alphaproteobacteria,2K1CI@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRD2_k127_7528012_0	420324.KI912025_gene67	4.95e-262	831.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,1JSCQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRD2_k127_7556173_14	685778.AORL01000022_gene1473	1.442e-26	111.0	COG0762@1|root,COG0762@2|Bacteria,1N73Q@1224|Proteobacteria,2UFZR@28211|Alphaproteobacteria,2K6UW@204457|Sphingomonadales	204457|Sphingomonadales	S	integral membrane protein	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRD2_k127_7556173_4	1090319.KE386571_gene1238	2.572e-124	407.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,2TRMH@28211|Alphaproteobacteria,2K0WW@204457|Sphingomonadales	204457|Sphingomonadales	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
SRD2_k127_7556173_1	1123267.JONN01000001_gene1898	1.175e-179	570.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2TQXE@28211|Alphaproteobacteria,2K0TI@204457|Sphingomonadales	204457|Sphingomonadales	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
SRD2_k127_7556173_9	1123267.JONN01000001_gene1896	4.874e-74	253.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2U5J1@28211|Alphaproteobacteria,2K3VX@204457|Sphingomonadales	204457|Sphingomonadales	S	adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRD2_k127_7556173_8	1112216.JH594425_gene1432	2.218e-91	309.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2TR2V@28211|Alphaproteobacteria,2K0FZ@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
SRD2_k127_7556173_5	1123267.JONN01000001_gene1893	2.658e-113	368.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2TR3M@28211|Alphaproteobacteria,2K04Q@204457|Sphingomonadales	204457|Sphingomonadales	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRD2_k127_7556173_3	1470591.BW41_01161	3.251e-132	426.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2TRT6@28211|Alphaproteobacteria,2K1NI@204457|Sphingomonadales	204457|Sphingomonadales	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRD2_k127_7556173_15	1123267.JONN01000001_gene1890	5.268e-20	93.0	293KA@1|root,2ZR29@2|Bacteria,1NKAC@1224|Proteobacteria,2UK1U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7556173_13	1030157.AFMP01000004_gene1967	7.81e-33	134.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2TR0C@28211|Alphaproteobacteria,2K5QM@204457|Sphingomonadales	204457|Sphingomonadales	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRD2_k127_7556173_7	1120705.FG95_03926	2.712e-93	316.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2TUPG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRD2_k127_7556173_2	1123267.JONN01000001_gene1886	1.915e-139	447.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2TS3H@28211|Alphaproteobacteria,2K055@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
SRD2_k127_7556173_6	1123267.JONN01000001_gene1885	9.018e-100	329.0	COG1011@1|root,COG1011@2|Bacteria,1PHPQ@1224|Proteobacteria,2TUDN@28211|Alphaproteobacteria,2KEBI@204457|Sphingomonadales	204457|Sphingomonadales	S	Hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRD2_k127_7556173_0	1123267.JONN01000001_gene1884	2.334e-252	799.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2U0VY@28211|Alphaproteobacteria,2K0U8@204457|Sphingomonadales	204457|Sphingomonadales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRD2_k127_7556173_11	1449076.JOOE01000003_gene3206	1.64e-54	202.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2UBWJ@28211|Alphaproteobacteria,2K4FF@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRD2_k127_7556173_10	1123267.JONN01000001_gene2064	2.137e-67	237.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2U72U@28211|Alphaproteobacteria,2K4IC@204457|Sphingomonadales	204457|Sphingomonadales	S	FeS assembly SUF system protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRD2_k127_7556173_12	279238.Saro_0199	1.16e-34	134.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TRNY@28211|Alphaproteobacteria,2JZVI@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRD2_k127_7572348_0	1123267.JONN01000002_gene322	0.0	1036.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2TQV4@28211|Alphaproteobacteria,2K28K@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRD2_k127_7572348_2	926566.Terro_4208	5.169e-31	130.0	COG3751@1|root,COG3751@2|Bacteria	2|Bacteria	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
SRD2_k127_7572348_1	1123267.JONN01000001_gene1202	2.283e-116	380.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2U0NP@28211|Alphaproteobacteria,2K0ZN@204457|Sphingomonadales	204457|Sphingomonadales	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
SRD2_k127_7572705_8	2340.JV46_02090	8.24e-11	64.0	COG1215@1|root,COG1215@2|Bacteria,1N3K8@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7572705_4	1123267.JONN01000001_gene2078	5.806e-81	282.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TT3Z@28211|Alphaproteobacteria,2K2A0@204457|Sphingomonadales	204457|Sphingomonadales	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRD2_k127_7572705_0	1123267.JONN01000001_gene2079	0.0	1194.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,2TR7N@28211|Alphaproteobacteria,2JZXM@204457|Sphingomonadales	204457|Sphingomonadales	L	helicase	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C
SRD2_k127_7572705_7	1123267.JONN01000001_gene2080	5.284e-30	124.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2UBS3@28211|Alphaproteobacteria,2K6XI@204457|Sphingomonadales	204457|Sphingomonadales	J	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
SRD2_k127_7572705_5	1123267.JONN01000001_gene2081	1.738e-64	221.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2U98K@28211|Alphaproteobacteria,2K4E8@204457|Sphingomonadales	204457|Sphingomonadales	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
SRD2_k127_7572705_6	1331060.RLDS_02535	3.323e-55	204.0	COG3713@1|root,COG3713@2|Bacteria,1RF1U@1224|Proteobacteria,2U8SJ@28211|Alphaproteobacteria,2K4FB@204457|Sphingomonadales	204457|Sphingomonadales	M	MltA-interacting protein MipA	-	-	-	-	-	-	-	-	-	-	-	-	MipA
SRD2_k127_7572705_1	745310.G432_17725	5.394e-303	943.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2TQNJ@28211|Alphaproteobacteria,2K22T@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2
SRD2_k127_7572705_3	1219035.NT2_04_02030	1.376e-159	507.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,2TT2D@28211|Alphaproteobacteria,2K1HF@204457|Sphingomonadales	204457|Sphingomonadales	EH	sulfate adenylyltransferase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRD2_k127_7572705_2	1219035.NT2_05_00020	1.496e-199	632.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,2K04M@204457|Sphingomonadales	204457|Sphingomonadales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16,TPR_2,TPR_8
SRD2_k127_7573391_2	1123267.JONN01000001_gene1536	1.729e-102	338.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2TQMT@28211|Alphaproteobacteria,2JZY0@204457|Sphingomonadales	204457|Sphingomonadales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRD2_k127_7573391_1	1219049.SP5_100_00010	6.491e-105	344.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2TT6A@28211|Alphaproteobacteria,2JZW8@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRD2_k127_7573391_3	1114964.L485_04195	4.313e-61	224.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2U9GC@28211|Alphaproteobacteria,2K4ET@204457|Sphingomonadales	204457|Sphingomonadales	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
SRD2_k127_7573391_0	1112214.AHIS01000061_gene2839	8.39e-190	607.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TRYI@28211|Alphaproteobacteria,2K0VP@204457|Sphingomonadales	204457|Sphingomonadales	C	FAD linked	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
SRD2_k127_7573391_5	1123267.JONN01000001_gene614	8.774e-17	87.0	COG1846@1|root,COG1846@2|Bacteria,1N2Q4@1224|Proteobacteria,2UC5A@28211|Alphaproteobacteria,2K54U@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR
SRD2_k127_7573391_4	235985.BBPN01000033_gene111	2.477e-44	172.0	COG0583@1|root,COG0583@2|Bacteria,2GK13@201174|Actinobacteria,2NJAM@228398|Streptacidiphilus	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRD2_k127_7615616_5	1123242.JH636435_gene796	5.176e-13	70.0	COG0477@1|root,COG0477@2|Bacteria,2J4Z6@203682|Planctomycetes	203682|Planctomycetes	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRD2_k127_7615616_7	1037409.BJ6T_74070	1.297e-06	52.0	2EQ0D@1|root,33HKU@2|Bacteria,1N7ES@1224|Proteobacteria,2UF3T@28211|Alphaproteobacteria,3K0WY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	MA20_44835	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7615616_6	398578.Daci_1754	7.226e-09	61.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2VI0E@28216|Betaproteobacteria,4ABVU@80864|Comamonadaceae	28216|Betaproteobacteria	L	Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
SRD2_k127_7615616_3	1082933.MEA186_03979	4.729e-41	163.0	COG0463@1|root,COG0463@2|Bacteria,1N8QE@1224|Proteobacteria,2UDFS@28211|Alphaproteobacteria,43HNH@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD2_k127_7615616_0	702113.PP1Y_AT18181	2.89e-236	747.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRD2_k127_7615616_4	232721.Ajs_3079	7.786e-38	156.0	COG3660@1|root,COG3660@2|Bacteria,1R70U@1224|Proteobacteria	1224|Proteobacteria	M	Nucleoside-diphosphate-sugar epimerase	-	-	-	ko:K07276	-	-	-	-	ko00000	-	-	-	Mito_fiss_Elm1
SRD2_k127_7615616_2	1336208.JADY01000010_gene3348	1.16e-104	347.0	COG1442@1|root,COG1442@2|Bacteria,1R5NA@1224|Proteobacteria,2U2U3@28211|Alphaproteobacteria,2JS2F@204441|Rhodospirillales	204441|Rhodospirillales	M	glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7615616_1	1123267.JONN01000001_gene508	1.637e-230	722.0	COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,2TTX5@28211|Alphaproteobacteria,2K0AH@204457|Sphingomonadales	204457|Sphingomonadales	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
SRD2_k127_7665186_9	279238.Saro_2222	7.279e-05	50.0	COG1846@1|root,COG1846@2|Bacteria,1NYW3@1224|Proteobacteria,2UTVX@28211|Alphaproteobacteria,2K6HH@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27
SRD2_k127_7665186_8	1090320.KB900605_gene1072	1.346e-14	80.0	COG1846@1|root,COG1846@2|Bacteria,1Q70R@1224|Proteobacteria,2VD4H@28211|Alphaproteobacteria,2K45Z@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7665186_6	1116472.MGMO_137c00120	1.436e-31	128.0	2CN2H@1|root,32SG5@2|Bacteria,1N4PY@1224|Proteobacteria,1SESE@1236|Gammaproteobacteria,1XGHH@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_7665186_5	161528.ED21_25988	4.592e-40	169.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1N7YB@1224|Proteobacteria,2V7CZ@28211|Alphaproteobacteria,2K2SU@204457|Sphingomonadales	204457|Sphingomonadales	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRD2_k127_7665186_0	1144307.PMI04_02905	7.507e-172	549.0	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,2TSYS@28211|Alphaproteobacteria,2K1WY@204457|Sphingomonadales	204457|Sphingomonadales	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRD2_k127_7665186_4	685778.AORL01000010_gene2800	4.582e-43	162.0	COG2202@1|root,COG2202@2|Bacteria,1NUVW@1224|Proteobacteria,2UREC@28211|Alphaproteobacteria,2K6CM@204457|Sphingomonadales	204457|Sphingomonadales	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_3
SRD2_k127_7665186_7	1123267.JONN01000001_gene614	7.892e-24	108.0	COG1846@1|root,COG1846@2|Bacteria,1N2Q4@1224|Proteobacteria,2UC5A@28211|Alphaproteobacteria,2K54U@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR
SRD2_k127_7665186_3	1112212.JH584235_gene3790	2.522e-77	263.0	COG4318@1|root,COG4318@2|Bacteria,1MVIY@1224|Proteobacteria,2TSB0@28211|Alphaproteobacteria,2K41P@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative ParB-like nuclease	-	-	-	-	-	-	-	-	-	-	-	-	ParBc_2
SRD2_k127_7665186_1	983920.Y88_3094	5.41e-128	427.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria,2K3UQ@204457|Sphingomonadales	204457|Sphingomonadales	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
SRD2_k127_7665186_2	13689.BV96_04153	5.063e-98	322.0	COG1708@1|root,COG2250@1|root,COG1708@2|Bacteria,COG2250@2|Bacteria,1PWC5@1224|Proteobacteria,2TT5M@28211|Alphaproteobacteria,2K1BT@204457|Sphingomonadales	204457|Sphingomonadales	S	Nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
SRD2_k127_7683746_12	392499.Swit_1233	5.684e-24	105.0	COG4254@1|root,COG4254@2|Bacteria,1N739@1224|Proteobacteria,2TY9V@28211|Alphaproteobacteria,2K5CY@204457|Sphingomonadales	204457|Sphingomonadales	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRD2_k127_7683746_8	1123517.JOMR01000001_gene250	6.552e-77	265.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,1RMUM@1236|Gammaproteobacteria,462GB@72273|Thiotrichales	72273|Thiotrichales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD2_k127_7683746_0	13689.BV96_03183	0.0	1019.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR38@28211|Alphaproteobacteria,2K3HH@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRD2_k127_7683746_9	1122604.JONR01000039_gene3760	6.712e-67	232.0	COG0778@1|root,COG0778@2|Bacteria,1PGJY@1224|Proteobacteria,1S99H@1236|Gammaproteobacteria,1XBXV@135614|Xanthomonadales	135614|Xanthomonadales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRD2_k127_7683746_6	1081640.AGFU01000020_gene1881	3.358e-98	327.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2TS3W@28211|Alphaproteobacteria,2K3VI@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC transporter	-	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
SRD2_k127_7683746_3	1081640.AGFU01000020_gene1882	3.229e-178	567.0	COG4591@1|root,COG4591@2|Bacteria,1Q2BY@1224|Proteobacteria,2TVP1@28211|Alphaproteobacteria,2K3FR@204457|Sphingomonadales	204457|Sphingomonadales	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SRD2_k127_7683746_5	1081640.AGFU01000020_gene1883	7.995e-103	345.0	COG0845@1|root,COG0845@2|Bacteria,1P540@1224|Proteobacteria,2U20J@28211|Alphaproteobacteria,2K2CE@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRD2_k127_7683746_1	46429.BV95_02812	2.771e-215	677.0	COG2312@1|root,COG2312@2|Bacteria,1MU2S@1224|Proteobacteria,2TWB5@28211|Alphaproteobacteria,2K7QR@204457|Sphingomonadales	204457|Sphingomonadales	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
SRD2_k127_7683746_7	794846.AJQU01000106_gene2935	3.672e-87	299.0	COG0596@1|root,COG0596@2|Bacteria,1Q47F@1224|Proteobacteria,2U3WB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRD2_k127_7683746_2	1197906.CAJQ02000001_gene2638	1.828e-192	610.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2TVFM@28211|Alphaproteobacteria,3JVKB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
SRD2_k127_7683746_15	876269.ARWA01000001_gene631	8.855e-10	65.0	COG0784@1|root,COG0784@2|Bacteria,1MX3Y@1224|Proteobacteria,2TT2R@28211|Alphaproteobacteria,3NA1E@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	phyR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma70_r4_2
SRD2_k127_7683746_13	1123267.JONN01000001_gene2384	3.367e-21	99.0	2AM5D@1|root,31BZP@2|Bacteria,1Q7Y4@1224|Proteobacteria,2VE3K@28211|Alphaproteobacteria,2K6UE@204457|Sphingomonadales	204457|Sphingomonadales	S	Low affinity iron permease	-	-	-	-	-	-	-	-	-	-	-	-	Iron_permease
SRD2_k127_7683746_10	1123269.NX02_09300	1.306e-32	132.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2UFRX@28211|Alphaproteobacteria,2K4R1@204457|Sphingomonadales	204457|Sphingomonadales	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRD2_k127_7683746_11	627192.SLG_17700	2.126e-31	129.0	COG5622@1|root,COG5622@2|Bacteria,1RIEJ@1224|Proteobacteria,2U7UE@28211|Alphaproteobacteria,2K400@204457|Sphingomonadales	204457|Sphingomonadales	N	Protein required for attachment to host cells	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach
SRD2_k127_7683746_4	318996.AXAZ01000044_gene2099	4.657e-143	466.0	COG1073@1|root,COG1926@1|root,COG1073@2|Bacteria,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,2U5HS@28211|Alphaproteobacteria,3JYIY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
SRD2_k127_7683746_14	946077.W5A_05738	1.472e-19	102.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1HZ1M@117743|Flavobacteriia	976|Bacteroidetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
SRD2_k127_7750193_18	1123267.JONN01000002_gene365	1.937e-11	64.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,2K0DA@204457|Sphingomonadales	204457|Sphingomonadales	S	MazG family	mazG	-	3.6.1.9	ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
SRD2_k127_7750193_5	1123267.JONN01000001_gene1217	6.481e-178	567.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2TUXJ@28211|Alphaproteobacteria,2K0SI@204457|Sphingomonadales	204457|Sphingomonadales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRD2_k127_7750193_13	1123267.JONN01000001_gene1216	1.821e-57	204.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2UBTW@28211|Alphaproteobacteria,2K2YT@204457|Sphingomonadales	204457|Sphingomonadales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
SRD2_k127_7750193_3	1123267.JONN01000001_gene1215	9.386e-232	723.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria,2K1KM@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRD2_k127_7750193_1	1123267.JONN01000001_gene1214	5.22e-271	853.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2TQTB@28211|Alphaproteobacteria,2K01N@204457|Sphingomonadales	204457|Sphingomonadales	T	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
SRD2_k127_7750193_7	1123267.JONN01000001_gene1213	2.273e-163	522.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2TRC8@28211|Alphaproteobacteria,2K0QH@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
SRD2_k127_7750193_8	1123267.JONN01000001_gene1212	6.664e-137	448.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,2TRQC@28211|Alphaproteobacteria,2K0Y0@204457|Sphingomonadales	204457|Sphingomonadales	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispDF	-	2.7.7.60,4.6.1.12	ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRD2_k127_7750193_11	1090318.ATTI01000001_gene1025	1.575e-67	235.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2U94H@28211|Alphaproteobacteria,2K40Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
SRD2_k127_7750193_15	1342301.JASD01000008_gene3523	3.175e-38	157.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2U7D8@28211|Alphaproteobacteria,3ZX6B@60136|Sulfitobacter	28211|Alphaproteobacteria	I	Polyketide cyclase / dehydrase and lipid transport	pasT	-	-	ko:K18588	-	-	-	-	ko00000	-	-	-	Polyketide_cyc
SRD2_k127_7750193_6	1123267.JONN01000001_gene1209	7.205e-169	544.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2TRP3@28211|Alphaproteobacteria,2K1H4@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRD2_k127_7750193_10	745310.G432_01120	2.374e-82	278.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2TRPD@28211|Alphaproteobacteria,2K1U7@204457|Sphingomonadales	204457|Sphingomonadales	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRD2_k127_7750193_16	1123267.JONN01000001_gene1208	6.274e-20	96.0	2DTUP@1|root,33MQD@2|Bacteria,1NPP7@1224|Proteobacteria,2UX90@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp
SRD2_k127_7750193_9	1123267.JONN01000001_gene1206	3.316e-105	346.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2TRE6@28211|Alphaproteobacteria,2K1CX@204457|Sphingomonadales	204457|Sphingomonadales	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
SRD2_k127_7750193_17	666681.M301_0541	1.191e-17	85.0	29Y0R@1|root,30JTN@2|Bacteria,1PJV1@1224|Proteobacteria,2W86X@28216|Betaproteobacteria,2KP2Z@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905
SRD2_k127_7750193_12	1242864.D187_002182	1.428e-58	209.0	COG4430@1|root,COG4430@2|Bacteria,1NEN6@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRD2_k127_7750193_0	1120705.FG95_03948	9.441e-312	960.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,2K0YK@204457|Sphingomonadales	204457|Sphingomonadales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
SRD2_k127_7750193_2	1123267.JONN01000001_gene1106	6.131e-234	734.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria,2K0TE@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.44	ko:K00666,ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD2_k127_7750193_14	1123267.JONN01000001_gene1105	2.394e-38	151.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2UBQB@28211|Alphaproteobacteria,2K5JW@204457|Sphingomonadales	204457|Sphingomonadales	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRD2_k127_7750193_4	1123267.JONN01000001_gene1104	2.149e-216	685.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2TRPB@28211|Alphaproteobacteria,2K0MV@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DUF3646
SRD2_k127_778676_3	290633.GOX2136	9.468e-100	341.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,2TVJ5@28211|Alphaproteobacteria,2JUXI@204441|Rhodospirillales	204441|Rhodospirillales	S	PA domain	-	-	-	ko:K01269	-	-	-	-	ko00000,ko01000	-	-	-	PA,Peptidase_M28
SRD2_k127_778676_2	1081640.AGFU01000051_gene867	8.518e-167	530.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2TSYI@28211|Alphaproteobacteria,2JZVM@204457|Sphingomonadales	204457|Sphingomonadales	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRD2_k127_778676_4	1449076.JOOE01000001_gene2261	4.791e-83	283.0	COG1392@1|root,COG1392@2|Bacteria,1QV5N@1224|Proteobacteria,2TWA9@28211|Alphaproteobacteria,2K1CT@204457|Sphingomonadales	204457|Sphingomonadales	P	Phosphate transport regulator	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	NUDIX,PhoU_div
SRD2_k127_778676_0	1123267.JONN01000001_gene1960	0.0	1144.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,2K0F8@204457|Sphingomonadales	204457|Sphingomonadales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
SRD2_k127_778676_1	685778.AORL01000009_gene3262	6.518e-213	671.0	COG2234@1|root,COG2234@2|Bacteria,1R6BQ@1224|Proteobacteria,2U2SM@28211|Alphaproteobacteria,2K3NR@204457|Sphingomonadales	204457|Sphingomonadales	S	Transferrin receptor-like dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28,TFR_dimer
SRD2_k127_7888506_2	1123267.JONN01000001_gene424	6.627e-58	206.0	COG1597@1|root,COG1597@2|Bacteria,1R78V@1224|Proteobacteria,2U0V0@28211|Alphaproteobacteria,2K03G@204457|Sphingomonadales	204457|Sphingomonadales	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRD2_k127_7888506_0	1123267.JONN01000001_gene423	1.128e-156	504.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2U55Q@28211|Alphaproteobacteria,2K07C@204457|Sphingomonadales	204457|Sphingomonadales	S	YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
SRD2_k127_7888506_1	1123267.JONN01000001_gene422	3.19e-126	420.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2TR76@28211|Alphaproteobacteria,2K1ZM@204457|Sphingomonadales	204457|Sphingomonadales	S	YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
SRD2_k127_790284_0	1123267.JONN01000001_gene1585	3.372e-248	771.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,2K0EY@204457|Sphingomonadales	204457|Sphingomonadales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRD2_k127_790284_8	1234595.C725_0245	2.859e-68	239.0	COG2312@1|root,COG2518@1|root,COG2312@2|Bacteria,COG2518@2|Bacteria,1MU2S@1224|Proteobacteria,2TWB5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Erythro_esteras,PCMT,Pribosyltran
SRD2_k127_790284_10	1245469.S58_31260	3.47e-67	241.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,3JUR1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRD2_k127_790284_5	161528.ED21_19282	7.549e-142	454.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2TSXS@28211|Alphaproteobacteria,2K0MM@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
SRD2_k127_790284_15	1123267.JONN01000001_gene1588	5.52e-20	100.0	COG2022@1|root,COG2022@2|Bacteria,1QYPA@1224|Proteobacteria,2TXU5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
SRD2_k127_790284_11	1041146.ATZB01000003_gene7012	4.446e-47	174.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2U9BV@28211|Alphaproteobacteria,4BE03@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRD2_k127_790284_12	1219035.NT2_01_03950	5.378e-47	176.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2U93Y@28211|Alphaproteobacteria,2K5JX@204457|Sphingomonadales	204457|Sphingomonadales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRD2_k127_790284_1	745310.G432_17935	8.576e-247	766.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,2K11Z@204457|Sphingomonadales	204457|Sphingomonadales	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRD2_k127_790284_16	629773.AORY01000015_gene1350	2.635e-12	73.0	2ABGX@1|root,310XZ@2|Bacteria,1PNZR@1224|Proteobacteria,2V1J5@28211|Alphaproteobacteria,2KBMT@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_790284_6	317655.Sala_0737	1.424e-119	394.0	COG3507@1|root,COG3507@2|Bacteria,1R3V6@1224|Proteobacteria,2UFF1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Glyco_hydro_43
SRD2_k127_790284_17	342610.Patl_1854	9.283e-06	51.0	COG2350@1|root,COG2350@2|Bacteria,1MZ8Y@1224|Proteobacteria,1SCAV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
SRD2_k127_790284_4	1287276.X752_22115	2.007e-159	513.0	COG2723@1|root,COG2723@2|Bacteria,1MWU7@1224|Proteobacteria,2TUXP@28211|Alphaproteobacteria,43N4R@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	beta-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42,Glycos_transf_1
SRD2_k127_790284_7	1123267.JONN01000002_gene286	2.775e-70	250.0	COG0457@1|root,COG1716@1|root,COG0457@2|Bacteria,COG1716@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,2K6JI@204457|Sphingomonadales	204457|Sphingomonadales	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,TPR_8,Trans_reg_C
SRD2_k127_790284_14	1123267.JONN01000002_gene287	2.288e-37	151.0	COG0758@1|root,COG0758@2|Bacteria,1R9P1@1224|Proteobacteria,2U30Q@28211|Alphaproteobacteria,2K3JF@204457|Sphingomonadales	204457|Sphingomonadales	LU	DNA mediated transformation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_790284_3	1123267.JONN01000002_gene288	6.925e-170	554.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2VF85@28211|Alphaproteobacteria,2KDYZ@204457|Sphingomonadales	204457|Sphingomonadales	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRD2_k127_790284_9	1123267.JONN01000002_gene289	2.957e-68	240.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2U450@28211|Alphaproteobacteria,2K4T7@204457|Sphingomonadales	204457|Sphingomonadales	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
SRD2_k127_790284_2	1112214.AHIS01000101_gene1620	2.05e-196	622.0	COG0477@1|root,COG2814@2|Bacteria,1MWKH@1224|Proteobacteria,2U0GU@28211|Alphaproteobacteria,2K459@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRD2_k127_790284_18	1123269.NX02_16160	0.0001424	52.0	COG0810@1|root,COG0810@2|Bacteria,1NB5F@1224|Proteobacteria,2UJ8K@28211|Alphaproteobacteria,2KDGQ@204457|Sphingomonadales	204457|Sphingomonadales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRD2_k127_792725_6	1123267.JONN01000001_gene1585	5.82e-55	193.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,2K0EY@204457|Sphingomonadales	204457|Sphingomonadales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRD2_k127_792725_16	1346791.M529_01635	7.266e-07	57.0	28YKP@1|root,2ZKEE@2|Bacteria,1NBD7@1224|Proteobacteria,2UHHD@28211|Alphaproteobacteria,2K531@204457|Sphingomonadales	204457|Sphingomonadales	S	Pilus assembly protein PilZ	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
SRD2_k127_792725_14	1545915.JROG01000003_gene1644	1.177e-22	113.0	COG5388@1|root,COG5388@2|Bacteria,1R74W@1224|Proteobacteria,2TUTW@28211|Alphaproteobacteria,2K1EC@204457|Sphingomonadales	204457|Sphingomonadales	S	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_792725_0	1123267.JONN01000001_gene1668	2.29e-219	691.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JZVD@204457|Sphingomonadales	204457|Sphingomonadales	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD2_k127_792725_9	1123267.JONN01000001_gene1635	2.425e-37	142.0	COG3255@1|root,COG3255@2|Bacteria,1Q4V4@1224|Proteobacteria,2VB9X@28211|Alphaproteobacteria,2K6UF@204457|Sphingomonadales	204457|Sphingomonadales	I	PFAM Sterol-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRD2_k127_792725_3	1123267.JONN01000001_gene1638	3.385e-128	412.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2TTE6@28211|Alphaproteobacteria,2K0EF@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRD2_k127_792725_13	1247963.JPHU01000001_gene2041	6.271e-25	117.0	2DEWU@1|root,2ZPJP@2|Bacteria,1N6PP@1224|Proteobacteria,2UI8P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_792725_4	279238.Saro_0566	5.858e-121	392.0	COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,2TQS5@28211|Alphaproteobacteria,2JZXA@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRD2_k127_792725_12	158500.BV97_03420	8.859e-27	114.0	COG5652@1|root,COG5652@2|Bacteria,1NGE7@1224|Proteobacteria,2UT6H@28211|Alphaproteobacteria,2K7IQ@204457|Sphingomonadales	204457|Sphingomonadales	S	PFAM VanZ	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD2_k127_792725_10	279238.Saro_2521	7.468e-36	146.0	COG5467@1|root,COG5467@2|Bacteria,1MZRN@1224|Proteobacteria,2UC1G@28211|Alphaproteobacteria,2K533@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1476
SRD2_k127_792725_11	1550073.JROH01000027_gene941	2.944e-29	120.0	COG0271@1|root,COG0271@2|Bacteria,1R3MM@1224|Proteobacteria,2UBUW@28211|Alphaproteobacteria,2K5YQ@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the BolA IbaG family	-	-	-	-	-	-	-	-	-	-	-	-	BolA
SRD2_k127_792725_7	1123267.JONN01000001_gene1647	1.172e-48	177.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2U9QB@28211|Alphaproteobacteria,2K55Y@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
SRD2_k127_792725_2	1123267.JONN01000001_gene1648	7.19e-154	496.0	COG0438@1|root,COG0438@2|Bacteria,1NU0D@1224|Proteobacteria,2U2M4@28211|Alphaproteobacteria,2K040@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
SRD2_k127_792725_5	1449076.JOOE01000002_gene1289	1.052e-108	362.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria,2K18T@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRD2_k127_792725_8	1007104.SUS17_2615	4.889e-48	185.0	2BX8M@1|root,31H0R@2|Bacteria,1MYMI@1224|Proteobacteria,2UB1B@28211|Alphaproteobacteria,2K27Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
SRD2_k127_792725_1	1123267.JONN01000001_gene1653	3.883e-191	600.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2TRPG@28211|Alphaproteobacteria,2K13Q@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRD2_k127_792725_15	1283299.AUKG01000002_gene4731	1.504e-12	68.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,4CPC1@84995|Rubrobacteria	84995|Rubrobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
SRD2_k127_7954297_1	450851.PHZ_c3225	8.313e-164	524.0	COG2312@1|root,COG2312@2|Bacteria,1MU2S@1224|Proteobacteria,2TY7R@28211|Alphaproteobacteria,2KHES@204458|Caulobacterales	204458|Caulobacterales	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Erythro_esteras,Pribosyltran
SRD2_k127_7954297_3	189753.AXAS01000014_gene5657	1.643e-71	252.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,3JUR1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRD2_k127_7954297_2	1122970.AUHC01000010_gene1660	5.967e-137	438.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2TSXS@28211|Alphaproteobacteria,2K0MM@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
SRD2_k127_7954297_5	1123267.JONN01000001_gene1588	2.7e-23	101.0	COG2022@1|root,COG2022@2|Bacteria,1QYPA@1224|Proteobacteria,2TXU5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
SRD2_k127_7954297_4	1219035.NT2_01_03950	4.127e-45	174.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2U93Y@28211|Alphaproteobacteria,2K5JX@204457|Sphingomonadales	204457|Sphingomonadales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRD2_k127_7954297_0	1030157.AFMP01000065_gene1113	4.495e-241	758.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,2K11Z@204457|Sphingomonadales	204457|Sphingomonadales	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
## 2224 queries scanned
## Total time (seconds): 16.455967664718628
## Rate: 135.15 q/s