## Wed Feb 18 17:59:35 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/SRD3_bin.31.fa -m mmseqs --output SRD3_bin.31 --output_dir /data/result/bins/wyx/eggqs50+/SRD3_bin.31 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRD3_k127_1007196_2	1128421.JAGA01000001_gene2427	7.549e-80	292.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2NPBQ@2323|unclassified Bacteria	2|Bacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	hemD	GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.107,2.5.1.61,4.2.1.75	ko:K01719,ko:K01749,ko:K02303,ko:K13542,ko:K13543	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084,R03165,R03194	RC00003,RC00871,RC01861,RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755,iJN678.hemD	HEM4,TP_methylase
SRD3_k127_1007196_3	1229780.BN381_60042	9.792e-71	263.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,3UWP6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRD3_k127_1007196_1	1313172.YM304_37850	4.557e-93	320.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4CN61@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRD3_k127_1007196_4	469371.Tbis_0260	1.705e-68	245.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,4DY6U@85010|Pseudonocardiales	201174|Actinobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRD3_k127_1007196_0	1229780.BN381_60045	1.034e-108	366.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,3UWG3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRD3_k127_101500_3	1123320.KB889689_gene530	6.11e-51	186.0	COG0318@1|root,COG0318@2|Bacteria,2GKZ6@201174|Actinobacteria	201174|Actinobacteria	IQ	synthetase	fadD17	GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0032787,GO:0042546,GO:0042759,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0072330,GO:1901576	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_101500_2	469383.Cwoe_0960	3.156e-106	357.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4CPSQ@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_101500_1	1341646.CBMO010000079_gene371	2.828e-110	362.0	COG1024@1|root,COG1024@2|Bacteria,2IBN1@201174|Actinobacteria,237N9@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD3_k127_101500_0	645465.ACUR01000575_gene1381	4.672e-115	393.0	COG1788@1|root,COG2057@1|root,COG1788@2|Bacteria,COG2057@2|Bacteria,2I931@201174|Actinobacteria	201174|Actinobacteria	I	Coenzyme A transferase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_trans
SRD3_k127_1035146_5	298654.FraEuI1c_3294	5.791e-36	139.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ES6E@85013|Frankiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_1035146_3	1394178.AWOO02000024_gene5626	3.354e-47	178.0	COG2050@1|root,COG2050@2|Bacteria,2IQXX@201174|Actinobacteria	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRD3_k127_1035146_2	479433.Caci_5172	1.266e-129	436.0	COG0842@1|root,COG0842@2|Bacteria,2GP9E@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRD3_k127_1035146_1	1449347.JQLN01000007_gene1062	5.911e-140	451.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,2M433@2063|Kitasatospora	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD3_k127_1035146_6	345341.KUTG_06993	2.76e-30	127.0	COG1846@1|root,COG1846@2|Bacteria,2IHP0@201174|Actinobacteria,4E7D4@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRD3_k127_1035146_0	351607.Acel_1142	3.017e-254	808.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4ERSA@85013|Frankiales	201174|Actinobacteria	V	ABC transporter, transmembrane region	msbA	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRD3_k127_1035146_4	1463821.JOGR01000004_gene2378	5.791e-41	158.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4EZPA@85014|Glycomycetales	201174|Actinobacteria	S	Haemolysin-III related	hlyIII	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRD3_k127_1038543_0	525909.Afer_0723	0.0	1434.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4CN9K@84992|Acidimicrobiia	84992|Acidimicrobiia	H	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRD3_k127_1040176_2	1229780.BN381_10208	3.874e-94	319.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,3UWHH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
SRD3_k127_1040176_0	1229780.BN381_10207	2.821e-151	491.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,3UWET@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRD3_k127_1040176_4	1313172.YM304_18470	4.873e-30	126.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4CN91@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal L27 protein	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRD3_k127_1040176_3	1313172.YM304_18460	1.876e-32	128.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4CN9R@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRD3_k127_1040176_1	31964.CMS1818	1.627e-135	447.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4FM45@85023|Microbacteriaceae	201174|Actinobacteria	J	Ribonuclease E/G family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
SRD3_k127_1048257_1	66875.JODY01000006_gene2209	2.167e-139	463.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	amiC_1	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRD3_k127_1048257_0	1157637.KB892156_gene4053	9.363e-148	483.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	fadE16	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_1048257_2	1133850.SHJG_2548	6.946e-56	204.0	COG1073@1|root,COG1073@2|Bacteria,2I2YU@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRD3_k127_1048257_3	526227.Mesil_1630	1.057e-22	114.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1WITS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
SRD3_k127_1059723_0	1254432.SCE1572_15620	1.062e-129	421.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria	1224|Proteobacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRD3_k127_1059723_1	330084.JNYZ01000016_gene5424	5.51e-117	385.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DZ7U@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0016020,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1559	PALP,Thr_dehydrat_C
SRD3_k127_1060413_4	1229780.BN381_100019	4.561e-88	291.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,3UWCE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	hrdD	-	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD3_k127_1060413_5	525909.Afer_1925	2.813e-85	295.0	COG0560@1|root,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,4CN1K@84992|Acidimicrobiia	84992|Acidimicrobiia	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRD3_k127_1060413_6	525909.Afer_1924	5.13e-72	251.0	COG0569@1|root,COG0569@2|Bacteria,2HH1S@201174|Actinobacteria,4CP21@84992|Acidimicrobiia	84992|Acidimicrobiia	C	TrkA-C domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRD3_k127_1060413_7	981369.JQMJ01000004_gene5399	6.196e-56	224.0	COG0569@1|root,COG0569@2|Bacteria,2GK4N@201174|Actinobacteria,2NGQT@228398|Streptacidiphilus	201174|Actinobacteria	P	TrkA-C domain	ceoB	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRD3_k127_1060413_2	525909.Afer_1922	4.58e-235	751.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4CNMX@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRD3_k127_1060413_1	1229780.BN381_130116	4.131e-256	815.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria,3UX5K@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRD3_k127_1060413_0	298653.Franean1_0309	0.0	1133.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,4ES4C@85013|Frankiales	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
SRD3_k127_1060413_9	1305732.JAGG01000001_gene143	7.063e-45	174.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4FMR0@85023|Microbacteriaceae	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3,Thymidylate_kin
SRD3_k127_1060413_8	1313172.YM304_03460	9.057e-56	216.0	COG0470@1|root,COG0470@2|Bacteria	2|Bacteria	L	replication factor c	holB	-	2.7.7.7	ko:K02341,ko:K02343,ko:K09384	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRD3_k127_1060413_3	1051632.TPY_3730	3.585e-142	462.0	COG0477@1|root,COG0477@2|Bacteria,1UHPS@1239|Firmicutes	1239|Firmicutes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	xylE	-	-	ko:K08138	-	-	-	-	ko00000,ko02000	2.A.1.1.3	-	-	Sugar_tr
SRD3_k127_1083481_0	1346791.M529_23080	3.539e-75	272.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VFYM@28211|Alphaproteobacteria,2KE0H@204457|Sphingomonadales	204457|Sphingomonadales	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRD3_k127_1130218_0	1313172.YM304_20790	4.918e-116	383.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4CMY2@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRD3_k127_1130218_1	1123267.JONN01000002_gene86	4.289e-96	332.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2TS98@28211|Alphaproteobacteria,2K035@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRD3_k127_1130218_2	1313172.YM304_20800	1.288e-93	333.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4CMYC@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRD3_k127_1141858_0	926560.KE387023_gene2049	2.685e-111	385.0	COG5001@1|root,COG5001@2|Bacteria,1WK20@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4
SRD3_k127_1141858_2	1121456.ATVA01000001_gene3124	2.859e-39	165.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,2M8CQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9
SRD3_k127_1141858_1	479434.Sthe_3338	8.274e-55	210.0	COG2329@1|root,COG5485@1|root,COG2329@2|Bacteria,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SRD3_k127_1141858_4	316273.XCV1510	2.508e-13	78.0	COG2388@1|root,COG2388@2|Bacteria,1N8AQ@1224|Proteobacteria,1SH12@1236|Gammaproteobacteria,1X83J@135614|Xanthomonadales	135614|Xanthomonadales	S	acetyltransferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
SRD3_k127_1141858_3	1957.JODX01000016_gene1947	4.994e-20	92.0	COG1985@1|root,COG1985@2|Bacteria,2GN2P@201174|Actinobacteria	201174|Actinobacteria	H	Pyrimidine reductase, riboflavin biosynthesis	-	-	1.1.1.193	ko:K00082	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R03458	RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
SRD3_k127_1143570_0	1121877.JQKF01000002_gene1677	3.066e-234	743.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4CMTK@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRD3_k127_1143570_4	1463855.JOHV01000049_gene3537	4.506e-05	51.0	COG4768@1|root,COG4768@2|Bacteria,2II1J@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF948)	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
SRD3_k127_1143570_2	1246995.AFR_04305	1.512e-50	193.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1143570_3	485913.Krac_7743	1.201e-14	85.0	COG4288@1|root,COG4934@1|root,COG4288@2|Bacteria,COG4934@2|Bacteria,2G8VN@200795|Chloroflexi	200795|Chloroflexi	V	PFAM N-acetylmuramoyl-L-alanine amidase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Pro-kuma_activ
SRD3_k127_1143570_1	1449347.JQLN01000005_gene4400	3.887e-55	207.0	COG4934@1|root,COG4934@2|Bacteria,2H5BC@201174|Actinobacteria	201174|Actinobacteria	O	Pro-kumamolisin, activation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pro-kuma_activ
SRD3_k127_1147176_2	1380393.JHVP01000014_gene4777	9.301e-78	268.0	COG4805@1|root,COG4805@2|Bacteria,2GJQT@201174|Actinobacteria,4ETWD@85013|Frankiales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1147176_1	1121877.JQKF01000003_gene1497	6.111e-144	462.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4CNND@84992|Acidimicrobiia	84992|Acidimicrobiia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.24,4.1.3.25,4.1.3.34	ko:K01644,ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,ko02020,map00630,map00660,map00680,map00720,map01120,map01200,map02020	M00346,M00373,M00376	R00237,R00362,R00473,R00934	RC00067,RC00307,RC00308,RC00311,RC00407,RC00502,RC01118,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
SRD3_k127_1147176_0	1229780.BN381_210057	2.747e-226	713.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,3UX9W@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.8.12	ko:K00248,ko:K14448	ko00071,ko00280,ko00630,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00630,map00650,map01100,map01110,map01120,map01200,map01212	M00373	R01175,R01178,R02661,R03172,R04751,R09293	RC00052,RC00068,RC00076,RC00120,RC00148,RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_1147176_5	298655.KI912267_gene6907	1.053e-13	79.0	COG0500@1|root,COG2226@2|Bacteria,2INEW@201174|Actinobacteria	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRD3_k127_1147176_4	1121877.JQKF01000001_gene1300	2.147e-54	198.0	2E3FZ@1|root,31FAR@2|Bacteria,2HGRD@201174|Actinobacteria,4CNTW@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1147176_3	1313172.YM304_14250	4.466e-68	234.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4CMYB@84992|Acidimicrobiia	84992|Acidimicrobiia	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRD3_k127_115118_1	1246995.AFR_21870	9.58e-36	139.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
SRD3_k127_115118_0	1206731.BAGB01000153_gene6816	4.572e-98	334.0	COG0657@1|root,COG0657@2|Bacteria,2GJYR@201174|Actinobacteria,4FY44@85025|Nocardiaceae	201174|Actinobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRD3_k127_115118_2	935839.JAGJ01000001_gene1033	9.902e-13	70.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria,4F4CP@85017|Promicromonosporaceae	201174|Actinobacteria	S	Hydrolase of the alpha beta-hydrolase	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
SRD3_k127_1162759_0	679197.HMPREF9336_03247	7.431e-92	314.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRD3_k127_1162759_1	357808.RoseRS_0952	5.685e-24	117.0	COG2605@1|root,COG2605@2|Bacteria	2|Bacteria	G	GHMP kinase	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,GHMP_kinases_C,GHMP_kinases_N
SRD3_k127_1163978_1	1463881.KL591005_gene5979	9.035e-43	162.0	COG1028@1|root,COG1028@2|Bacteria,2HGA2@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_1163978_0	378806.STAUR_0058	1.028e-51	187.0	COG0789@1|root,COG0789@2|Bacteria,1RH2U@1224|Proteobacteria,42TT2@68525|delta/epsilon subdivisions,2WR2A@28221|Deltaproteobacteria,2Z14E@29|Myxococcales	28221|Deltaproteobacteria	K	MerR, DNA binding	soxR	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRD3_k127_1163978_2	35754.JNYJ01000013_gene1052	8.276e-35	153.0	COG1948@1|root,COG4880@2|Bacteria,2I8JU@201174|Actinobacteria,4D8V4@85008|Micromonosporales	201174|Actinobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
SRD3_k127_1166022_0	1229780.BN381_50171	1.754e-84	284.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,3UW80@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
SRD3_k127_1166022_2	1313172.YM304_19730	2.567e-48	188.0	COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4CN4U@84992|Acidimicrobiia	84992|Acidimicrobiia	FG	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRD3_k127_1166022_1	477641.MODMU_0444	2.854e-62	224.0	COG0438@1|root,COG0438@2|Bacteria,2IFGX@201174|Actinobacteria,4EW3I@85013|Frankiales	201174|Actinobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRD3_k127_1191624_4	1313172.YM304_08940	1.259e-26	121.0	COG1214@1|root,COG1214@2|Bacteria	2|Bacteria	O	tRNA threonylcarbamoyladenosine modification	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRD3_k127_1191624_3	1229780.BN381_130035	1.277e-47	176.0	COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria,3UWXZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	FR47-like protein	rimI	GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRD3_k127_1191624_1	1313172.YM304_08960	4.303e-123	404.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CMUH@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRD3_k127_1191624_2	525909.Afer_0443	3.877e-48	173.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4CN66@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRD3_k127_1191624_0	1121877.JQKF01000009_gene505	6.522e-266	827.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CMU0@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRD3_k127_1205030_2	258594.RPA3076	4.001e-17	92.0	COG2199@1|root,COG2199@2|Bacteria,1PQK4@1224|Proteobacteria,2TSC7@28211|Alphaproteobacteria,3JV2P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GGDEF
SRD3_k127_1205030_1	525909.Afer_1733	6.681e-35	155.0	COG2267@1|root,COG2267@2|Bacteria,2I5RV@201174|Actinobacteria,4CNT3@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRD3_k127_1205030_0	1313172.YM304_23290	0.0	1092.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4CMWS@84992|Acidimicrobiia	84992|Acidimicrobiia	C	2-oxoglutarate dehydrogenase N-terminus	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRD3_k127_1219701_1	1229780.BN381_20106	2.193e-239	759.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,3UW8A@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRD3_k127_1219701_13	1229780.BN381_20103	2.428e-60	214.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,3UWQE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRD3_k127_1219701_16	298653.Franean1_0781	2.444e-31	135.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4ESJF@85013|Frankiales	201174|Actinobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRD3_k127_1219701_7	525909.Afer_1597	3.806e-146	468.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CMVQ@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRD3_k127_1219701_10	1313172.YM304_33080	4.93e-89	306.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4CMZA@84992|Acidimicrobiia	84992|Acidimicrobiia	M	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
SRD3_k127_1219701_0	1120934.KB894412_gene3244	7.388e-252	810.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4DZ29@85010|Pseudonocardiales	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD2	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRD3_k127_1219701_3	882083.SacmaDRAFT_5378	4.367e-215	711.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4DZTM@85010|Pseudonocardiales	201174|Actinobacteria	I	Acetyl propionyl-CoA carboxylase, alpha subunit	-	-	6.4.1.3,6.4.1.4	ko:K01965,ko:K01968	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00036,M00373,M00741	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRD3_k127_1219701_2	326424.FRAAL1670	9.716e-223	737.0	COG3185@1|root,COG3185@2|Bacteria,2GJNC@201174|Actinobacteria	201174|Actinobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
SRD3_k127_1219701_4	882083.SacmaDRAFT_5380	2.331e-168	566.0	COG1960@1|root,COG1960@2|Bacteria,2GNFB@201174|Actinobacteria,4DY21@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_1219701_8	298654.FraEuI1c_0568	4.956e-99	350.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRD3_k127_1219701_12	981369.JQMJ01000004_gene574	3.574e-73	265.0	COG0204@1|root,COG0204@2|Bacteria,2GNBB@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRD3_k127_1219701_6	525368.HMPREF0591_3092	3.419e-156	505.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,232Z7@1762|Mycobacteriaceae	201174|Actinobacteria	IT	PFAM Adenylate and Guanylate cyclase catalytic domain	lipJ	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRD3_k127_1219701_9	1121877.JQKF01000012_gene346	1.477e-95	330.0	COG2043@1|root,COG2043@2|Bacteria,2ISFS@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
SRD3_k127_1219701_14	931627.MycrhDRAFT_4888	1.503e-54	194.0	COG0432@1|root,COG0432@2|Bacteria,2IHWS@201174|Actinobacteria,2398U@1762|Mycobacteriaceae	201174|Actinobacteria	S	Uncharacterised protein family UPF0047	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0047
SRD3_k127_1219701_5	1229780.BN381_80190	9.731e-160	526.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria	201174|Actinobacteria	S	unusual protein kinase	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ABC1,APH
SRD3_k127_1219701_11	1463825.JNXC01000011_gene301	5.711e-74	256.0	COG0386@1|root,COG0386@2|Bacteria,2IFJH@201174|Actinobacteria,4E367@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the glutathione peroxidase family	gpx	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
SRD3_k127_1219701_15	1173028.ANKO01000160_gene5070	3.097e-45	173.0	COG0637@1|root,COG0637@2|Bacteria,1G6EG@1117|Cyanobacteria,1HD99@1150|Oscillatoriales	1117|Cyanobacteria	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	3.1.3.23	ko:K19270	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2
SRD3_k127_1228353_3	1229780.BN381_50085	6.394e-45	183.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,3UX3T@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRD3_k127_1228353_0	1120936.KB907209_gene1792	7.063e-136	457.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,BPD_transp_1,oligo_HPY
SRD3_k127_1228353_2	1120936.KB907209_gene1793	1.783e-70	249.0	COG1173@1|root,COG1173@2|Bacteria,2IB56@201174|Actinobacteria	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRD3_k127_1228353_1	1120936.KB907209_gene1794	3.452e-89	306.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4EM9K@85012|Streptosporangiales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRD3_k127_1228353_4	1120936.KB907209_gene1795	0.0003798	44.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4EMZ3@85012|Streptosporangiales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD3_k127_122978_3	68570.DC74_6072	1.681e-53	206.0	COG1232@1|root,COG1232@2|Bacteria,2GMMA@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRD3_k127_122978_2	1382304.JNIL01000001_gene1030	3.726e-71	251.0	COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli	91061|Bacilli	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRD3_k127_122978_0	479433.Caci_6783	1.276e-132	432.0	COG0407@1|root,COG0407@2|Bacteria,2GMY6@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRD3_k127_122978_1	1313172.YM304_09360	4.847e-83	285.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4CMUM@84992|Acidimicrobiia	84992|Acidimicrobiia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19
SRD3_k127_1235677_0	1313172.YM304_21620	8.201e-206	656.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CMVA@84992|Acidimicrobiia	84992|Acidimicrobiia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,UVR,UvrC_HhH_N
SRD3_k127_1235677_1	1229780.BN381_410040	4.76e-181	580.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,3UWB7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRD3_k127_123868_1	1048339.KB913029_gene3336	7.199e-33	129.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4ERJ2@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRD3_k127_123868_0	1206730.BAGA01000057_gene2539	8.424e-84	295.0	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria,4FV06@85025|Nocardiaceae	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	-	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRD3_k127_123868_2	1502851.FG93_03402	1.626e-07	53.0	COG0346@1|root,COG0346@2|Bacteria,1N15G@1224|Proteobacteria,2UCYE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD3_k127_1253905_3	525909.Afer_0352	1.947e-93	318.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4CMRV@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Histidine kinase	-	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2
SRD3_k127_1253905_4	66875.JODY01000002_gene5228	1.568e-63	228.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD3_k127_1253905_2	926560.KE387023_gene2722	1.558e-101	362.0	COG5002@1|root,COG5002@2|Bacteria,1WNHC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg
SRD3_k127_1253905_5	1229780.BN381_310068	2.825e-37	144.0	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,3UWR8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB	GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRD3_k127_1253905_6	745776.DGo_CA0151	8.613e-25	113.0	COG0584@1|root,COG0584@2|Bacteria,1WK5D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRD3_k127_1253905_1	1229780.BN381_310071	1.834e-106	351.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,3UWNK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRD3_k127_1253905_0	1313172.YM304_09920	1.469e-111	370.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4CMXZ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Electron transfer flavoprotein domain	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRD3_k127_1256599_13	312284.A20C1_07538	8.038e-35	142.0	COG1989@1|root,COG1989@2|Bacteria,2HH3X@201174|Actinobacteria,3UXHM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	NOU	Type IV leader peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	DiS_P_DiS,Peptidase_A24
SRD3_k127_1256599_0	351607.Acel_1322	9.32e-180	594.0	COG2804@1|root,COG2804@2|Bacteria,2I8C2@201174|Actinobacteria,4ES0V@85013|Frankiales	201174|Actinobacteria	NU	General secretory system II, protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRD3_k127_1256599_2	1095767.CAHD01000205_gene848	1.33e-124	419.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria	201174|Actinobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRD3_k127_1256599_5	351607.Acel_1320	1.395e-100	341.0	COG1459@1|root,COG1459@2|Bacteria,2GQW0@201174|Actinobacteria,4ERP7@85013|Frankiales	201174|Actinobacteria	NU	Type II secretion system (T2SS), protein F	tapC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRD3_k127_1256599_6	1306174.JODP01000013_gene7517	1.779e-61	233.0	COG4972@1|root,COG4972@2|Bacteria,2IBNF@201174|Actinobacteria	201174|Actinobacteria	NU	pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRD3_k127_1256599_15	929712.KI912613_gene3438	4.516e-08	64.0	COG2165@1|root,COG2165@2|Bacteria,2GTN8@201174|Actinobacteria,4CQSF@84995|Rubrobacteria	84995|Rubrobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRD3_k127_1256599_16	748449.Halha_1788	1.179e-05	55.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	gspG	-	-	ko:K02456,ko:K02650,ko:K02655	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	ComP_DUS,N_methyl,T2SSG
SRD3_k127_1256599_3	1313172.YM304_05230	2.513e-124	418.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria	201174|Actinobacteria	E	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_1256599_11	68219.JNXI01000002_gene3944	8.931e-40	162.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
SRD3_k127_1256599_12	525909.Afer_0577	1.703e-35	146.0	COG3336@1|root,COG3336@2|Bacteria,2HG9Q@201174|Actinobacteria,4CN83@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	ko:K02862	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
SRD3_k127_1256599_10	1313172.YM304_14840	1.432e-47	185.0	COG2378@1|root,COG2378@2|Bacteria,2HGFE@201174|Actinobacteria,4CND2@84992|Acidimicrobiia	84992|Acidimicrobiia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
SRD3_k127_1256599_9	1229780.BN381_400038	3.756e-51	200.0	COG2378@1|root,COG2378@2|Bacteria,2GMAU@201174|Actinobacteria,3UWZY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	WYL domain	pafC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRD3_k127_1256599_8	1380390.JIAT01000012_gene3281	1.402e-53	214.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4CTKF@84995|Rubrobacteria	84995|Rubrobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
SRD3_k127_1256599_14	512565.AMIS_67980	3.551e-09	61.0	2DQ34@1|root,334JF@2|Bacteria,2HUUG@201174|Actinobacteria,4DG16@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1256599_1	222534.KB893670_gene3638	2.844e-125	420.0	COG0502@1|root,COG0502@2|Bacteria,2GIUE@201174|Actinobacteria,4ETY2@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1589	BATS,Radical_SAM
SRD3_k127_1256599_4	1078020.KEK_12303	3.057e-120	392.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,238CW@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_1270079_2	1122998.AUHZ01000006_gene664	6.045e-05	46.0	COG1807@1|root,COG1807@2|Bacteria,2GJPU@201174|Actinobacteria,4DN80@85009|Propionibacteriales	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRD3_k127_1270079_1	1298864.AUEQ01000008_gene2595	2.675e-59	216.0	COG1807@1|root,COG1807@2|Bacteria,2GJPU@201174|Actinobacteria,235PY@1762|Mycobacteriaceae	201174|Actinobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRD3_k127_1270079_0	1123368.AUIS01000006_gene566	2.366e-124	432.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4,Response_reg
SRD3_k127_1282713_3	2002.JOEQ01000042_gene5942	1.14e-28	117.0	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_1282713_5	298654.FraEuI1c_4998	2.488e-11	70.0	29WQV@1|root,30IBV@2|Bacteria,2GZ2Y@201174|Actinobacteria,4ETJK@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1282713_2	196162.Noca_0302	3.668e-31	129.0	COG5517@1|root,COG5517@2|Bacteria,2IN5V@201174|Actinobacteria,4DQBF@85009|Propionibacteriales	201174|Actinobacteria	Q	SnoaL-like domain	baiE	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRD3_k127_1282713_0	269800.Tfu_0278	6.858e-180	579.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4EG8D@85012|Streptosporangiales	201174|Actinobacteria	H	Aminotransferase class-III	tpa	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRD3_k127_1282713_1	443906.CMM_1174	3.727e-45	173.0	COG1522@1|root,COG1522@2|Bacteria,2GP1P@201174|Actinobacteria,4FNCP@85023|Microbacteriaceae	201174|Actinobacteria	K	helix_turn_helix ASNC type	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRD3_k127_1282713_4	754252.PFREUD_19260	2.859e-24	104.0	COG0001@1|root,COG0001@2|Bacteria,2HBVS@201174|Actinobacteria,4DU4P@85009|Propionibacteriales	201174|Actinobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD3_k127_1284245_0	298654.FraEuI1c_4032	3.41e-72	261.0	COG3559@1|root,COG3559@2|Bacteria,2GMSI@201174|Actinobacteria,4EVAJ@85013|Frankiales	201174|Actinobacteria	M	Exporter of polyketide	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRD3_k127_1284245_1	1394178.AWOO02000081_gene2209	3.606e-46	180.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,4EH1N@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA thioesterase	-	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
SRD3_k127_1284245_2	101510.RHA1_ro04095	4.498e-20	89.0	COG3832@1|root,COG3832@2|Bacteria,2IHQ1@201174|Actinobacteria,4G1C6@85025|Nocardiaceae	201174|Actinobacteria	S	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRD3_k127_1351673_2	926569.ANT_22620	6.464e-79	276.0	COG1086@1|root,COG1086@2|Bacteria,2G5M8@200795|Chloroflexi	200795|Chloroflexi	GM	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
SRD3_k127_1351673_0	2002.JOEQ01000036_gene676	4.504e-169	547.0	COG0677@1|root,COG0677@2|Bacteria,2GK5K@201174|Actinobacteria,4EH4I@85012|Streptosporangiales	201174|Actinobacteria	M	UDP binding domain	-	-	1.1.1.136,1.1.1.336	ko:K02472,ko:K13015	ko00520,ko05111,map00520,map05111	-	R00421,R03317	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRD3_k127_1351673_1	1193181.BN10_720026	2.174e-100	360.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria,4FFZX@85021|Intrasporangiaceae	201174|Actinobacteria	GM	GDP-D-mannose dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRD3_k127_1362494_8	479433.Caci_8312	2.12e-18	99.0	2BMGV@1|root,32G1K@2|Bacteria,2IP6V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1362494_7	40571.JOEA01000014_gene1906	8.273e-19	94.0	2B1ET@1|root,31TVH@2|Bacteria,2GT2S@201174|Actinobacteria,4EBC4@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1362494_2	1121272.KB903292_gene3948	3.703e-70	261.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRD3_k127_1362494_0	285514.JNWO01000002_gene4939	1.479e-134	452.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD3_k127_1362494_9	1380390.JIAT01000014_gene6050	3.368e-08	67.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4CRJD@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRD3_k127_1362494_3	463191.SSEG_00278	1.339e-65	229.0	COG2318@1|root,COG2318@2|Bacteria,2GMS2@201174|Actinobacteria	201174|Actinobacteria	E	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRD3_k127_1362494_6	326424.FRAAL5554	1.523e-37	152.0	COG1576@1|root,COG1576@2|Bacteria,2IGAN@201174|Actinobacteria	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRD3_k127_1362494_1	882086.SacxiDRAFT_4285	1.849e-72	262.0	COG2378@1|root,COG2378@2|Bacteria,2GKFU@201174|Actinobacteria,4DYQY@85010|Pseudonocardiales	201174|Actinobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRD3_k127_1362494_4	1229780.BN381_150047	3.571e-56	199.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,3UWVQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Glyoxalase-like domain	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRD3_k127_1362494_5	525909.Afer_0105	3.904e-51	183.0	COG0604@1|root,COG0604@2|Bacteria,2GKFF@201174|Actinobacteria,4CMSB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Zinc-binding dehydrogenase	-	-	1.3.1.86	ko:K17829	ko00650,ko01120,ko01130,ko01200,map00650,map01120,map01130,map01200	-	R09738	RC00076	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_1380736_4	391625.PPSIR1_18642	3.928e-53	209.0	COG2730@1|root,COG2730@2|Bacteria,1N21U@1224|Proteobacteria,435AG@68525|delta/epsilon subdivisions,2WZMJ@28221|Deltaproteobacteria,2Z2DK@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
SRD3_k127_1380736_10	1430440.MGMSRv2_0614	5.733e-07	62.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1N5RX@1224|Proteobacteria,2UK6G@28211|Alphaproteobacteria,2JUV6@204441|Rhodospirillales	204441|Rhodospirillales	M	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
SRD3_k127_1380736_2	1068978.AMETH_0524	1.685e-69	259.0	COG0367@1|root,COG0367@2|Bacteria,2IG1S@201174|Actinobacteria	201174|Actinobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
SRD3_k127_1380736_5	1122609.AUGT01000008_gene2895	1.703e-44	177.0	COG1132@1|root,COG1132@2|Bacteria,2IKZX@201174|Actinobacteria,4DTHX@85009|Propionibacteriales	201174|Actinobacteria	V	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1380736_7	1122609.AUGT01000008_gene2894	2.356e-16	85.0	2FI94@1|root,34A1K@2|Bacteria,2GXPU@201174|Actinobacteria,4DVJH@85009|Propionibacteriales	201174|Actinobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core3
SRD3_k127_1380736_8	1032480.MLP_48970	2.3e-12	71.0	2DRDY@1|root,33BC0@2|Bacteria,2GT2X@201174|Actinobacteria,4DWBD@85009|Propionibacteriales	201174|Actinobacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRD3_k127_1380736_9	1121403.AUCV01000041_gene185	1.252e-10	73.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRD3_k127_1380736_6	272557.APE_2516	6.384e-42	179.0	COG1131@1|root,arCOG00194@2157|Archaea,2XPS7@28889|Crenarchaeota	28889|Crenarchaeota	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD3_k127_1380736_3	926550.CLDAP_04540	4.587e-60	229.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRD3_k127_1380736_0	2045.KR76_22870	3.818e-141	461.0	COG0451@1|root,COG0451@2|Bacteria,2GP0W@201174|Actinobacteria,4DQ40@85009|Propionibacteriales	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRD3_k127_1380736_1	1089549.AZUQ01000001_gene2442	1.066e-79	278.0	COG1922@1|root,COG1922@2|Bacteria,2ICDG@201174|Actinobacteria,4EYRY@85014|Glycomycetales	201174|Actinobacteria	M	Glycosyl transferase WecB/TagA/CpsF family	rffM	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
SRD3_k127_1395953_1	1370120.AUWR01000019_gene970	2.058e-75	256.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,232FY@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_1395953_0	1123320.KB889684_gene2300	1.592e-85	296.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA12	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD3_k127_1405590_0	1121877.JQKF01000022_gene2268	3.741e-144	465.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4CMWI@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRD3_k127_1405590_1	1313172.YM304_21150	5.918e-107	372.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4CNTM@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRD3_k127_1405590_2	1313172.YM304_24220	1.185e-59	222.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CN8K@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRD3_k127_1405590_3	525909.Afer_1266	1.973e-59	208.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CN13@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRD3_k127_141451_1	1313172.YM304_10900	7.399e-46	169.0	COG0312@1|root,COG0312@2|Bacteria,2HGNU@201174|Actinobacteria,4CNQT@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRD3_k127_141451_2	525909.Afer_0488	4.456e-26	112.0	COG2331@1|root,COG2331@2|Bacteria,2HGEB@201174|Actinobacteria,4CP29@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_141451_0	1121877.JQKF01000003_gene1581	2.284e-72	252.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4CMYS@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRD3_k127_1422005_1	1108045.GORHZ_069_01120	1.051e-48	183.0	COG1020@1|root,COG1020@2|Bacteria,2GKU0@201174|Actinobacteria,4GD5R@85026|Gordoniaceae	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRD3_k127_1422005_0	477641.MODMU_4673	4.782e-71	267.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4ESA1@85013|Frankiales	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	tgs3	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRD3_k127_1422005_2	1229780.BN381_60056	2.052e-39	151.0	COG1670@1|root,COG1670@2|Bacteria,2IS6V@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRD3_k127_1457052_3	981369.JQMJ01000004_gene3977	2.59e-05	53.0	2FB55@1|root,343BG@2|Bacteria,2IKSK@201174|Actinobacteria,2NJ1W@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1457052_2	1120936.KB907212_gene5136	1.687e-46	173.0	COG2318@1|root,COG2318@2|Bacteria,2HUJD@201174|Actinobacteria,4EJN9@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRD3_k127_1457052_0	330084.JNYZ01000010_gene6836	2.271e-118	399.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4EARD@85010|Pseudonocardiales	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Choline_sulf_C,Sulfatase
SRD3_k127_1457052_1	1122609.AUGT01000005_gene1735	1.981e-84	297.0	COG1073@1|root,COG1073@2|Bacteria,2IAYK@201174|Actinobacteria,4DQB0@85009|Propionibacteriales	201174|Actinobacteria	S	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP
SRD3_k127_1464923_5	1120971.AUCA01000001_gene1692	3.954e-09	62.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,4HAIQ@91061|Bacilli,2784W@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRD3_k127_1464923_4	1177594.MIC448_800020	2.713e-39	155.0	COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria,4FP3B@85023|Microbacteriaceae	201174|Actinobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
SRD3_k127_1464923_0	1229780.BN381_110031	7.001e-162	533.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,3UW8F@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Fumarate reductase flavoprotein C-term	nadB	GO:0008150,GO:0040007	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1595	FAD_binding_2,Succ_DH_flav_C
SRD3_k127_1464923_1	1229780.BN381_110032	6.023e-86	308.0	COG0157@1|root,COG0157@2|Bacteria,2GV9P@201174|Actinobacteria,3UWIJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Quinolinate phosphoribosyl transferase, N-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRD3_k127_1464923_2	1229780.BN381_110048	8.077e-85	289.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria,3UWI1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRD3_k127_1464923_3	1229780.BN381_110049	4.565e-81	301.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,3UW8P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRD3_k127_148418_3	656024.FsymDg_2246	2.235e-18	94.0	2EUZ8@1|root,33NEF@2|Bacteria,2GM36@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_148418_1	1267533.KB906734_gene3952	8.416e-36	153.0	2DNAS@1|root,32WH6@2|Bacteria,3Y5UC@57723|Acidobacteria,2JKNS@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_148418_0	1068980.ARVW01000001_gene7824	2.039e-75	261.0	28HG7@1|root,2Z7S3@2|Bacteria,2GMJK@201174|Actinobacteria,4DZ4Y@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Wyosine base formation	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N,Wyosine_form
SRD3_k127_148418_2	1056816.JAFQ01000003_gene7198	1.035e-30	129.0	COG1309@1|root,COG1309@2|Bacteria,2H131@201174|Actinobacteria,4FZ31@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRD3_k127_1487921_3	1121877.JQKF01000002_gene1720	1.862e-23	116.0	COG1003@1|root,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4CMXT@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Glycine cleavage system P-protein	-	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRD3_k127_1487921_0	525909.Afer_1119	7.602e-129	432.0	COG0403@1|root,COG0403@2|Bacteria,2IBH2@201174|Actinobacteria,4CNJP@84992|Acidimicrobiia	84992|Acidimicrobiia	C	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRD3_k127_1487921_1	1229780.BN381_40087	2.151e-115	383.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,3UWIC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRD3_k127_1487921_2	671143.DAMO_2813	2.619e-30	125.0	COG1102@1|root,COG1102@2|Bacteria,2NRB0@2323|unclassified Bacteria	2|Bacteria	F	Cytidylate kinase-like family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Cytidylate_kin2,GAF_2,Pribosyltran
SRD3_k127_1497568_2	1229780.BN381_130009	1.184e-123	412.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,3UW9D@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Phosphoribosylglycinamide synthetase, C domain	purD	GO:0008150,GO:0040007	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRD3_k127_1497568_1	1229780.BN381_130003	6.126e-206	647.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,3UWF4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRD3_k127_1497568_5	1463936.JOJI01000006_gene4177	5.61e-23	104.0	COG0346@1|root,COG0346@2|Bacteria,2ISPK@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD3_k127_1497568_0	1121877.JQKF01000006_gene914	0.0	1085.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4CMTX@84992|Acidimicrobiia	84992|Acidimicrobiia	O	C-terminal, D2-small domain, of ClpB protein	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRD3_k127_1497568_3	525909.Afer_1963	4.519e-38	152.0	COG0789@1|root,COG0789@2|Bacteria,2GR1T@201174|Actinobacteria,4CN4Z@84992|Acidimicrobiia	84992|Acidimicrobiia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRD3_k127_1497568_4	1380347.JNII01000007_gene239	1.803e-36	141.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4ERZT@85013|Frankiales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRD3_k127_1498481_1	525909.Afer_1448	3.433e-21	100.0	COG0477@1|root,COG2814@2|Bacteria,2GKRT@201174|Actinobacteria,4CN19@84992|Acidimicrobiia	84992|Acidimicrobiia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_1498481_0	469383.Cwoe_4211	8.138e-305	950.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4CQXA@84995|Rubrobacteria	84995|Rubrobacteria	C	Phosphoenolpyruvate carboxykinase C-terminal P-loop domain	-	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SRD3_k127_1498481_2	1121957.ATVL01000012_gene813	2.922e-14	79.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,47JR7@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRD3_k127_1498560_1	977880.RALTA_B0515	1.152e-63	228.0	COG1028@1|root,COG1028@2|Bacteria,1P48D@1224|Proteobacteria,2VQPV@28216|Betaproteobacteria,1KFSX@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.357	ko:K19811	-	-	-	-	ko00000,ko01000	-	-	-	adh_short,adh_short_C2
SRD3_k127_1498560_2	1229780.BN381_70005	1.128e-25	115.0	COG0216@1|root,COG0216@2|Bacteria,2I7Z4@201174|Actinobacteria	201174|Actinobacteria	J	chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SRD3_k127_1498560_0	1157708.KB907451_gene4573	2.641e-77	262.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VMWW@28216|Betaproteobacteria,4ABTA@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRD3_k127_1507743_1	1229780.BN381_130043	1.749e-160	534.0	COG0519@1|root,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,3UWCD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRD3_k127_1507743_0	1121877.JQKF01000009_gene498	8.938e-208	653.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CNDM@84992|Acidimicrobiia	84992|Acidimicrobiia	F	IMP dehydrogenase / GMP reductase domain	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRD3_k127_1507743_2	1229780.BN381_130040	2.528e-36	145.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,3UWZK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRD3_k127_1528271_7	369723.Strop_4550	7.679e-15	76.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,4DC71@85008|Micromonosporales	201174|Actinobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
SRD3_k127_1528271_1	2045.KR76_18805	2.919e-127	420.0	COG3392@1|root,COG3392@2|Bacteria,2IBCB@201174|Actinobacteria,4DPB3@85009|Propionibacteriales	201174|Actinobacteria	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K07318	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MethyltransfD12
SRD3_k127_1528271_2	1206730.BAGA01000072_gene1992	1.969e-117	386.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4FX46@85025|Nocardiaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_1528271_4	1380356.JNIK01000013_gene3939	2.499e-52	204.0	COG0477@1|root,COG2814@2|Bacteria,2H1TJ@201174|Actinobacteria,4EUWV@85013|Frankiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_1528271_5	1229780.BN381_10089	3.952e-38	148.0	COG3255@1|root,COG3255@2|Bacteria,2H0GP@201174|Actinobacteria	201174|Actinobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1528271_3	1348663.KCH_21970	1.528e-58	214.0	COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria,2M2JZ@2063|Kitasatospora	201174|Actinobacteria	S	Serine aminopeptidase, S33	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
SRD3_k127_1528271_6	1380347.JNII01000007_gene662	6.116e-23	112.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4ESZM@85013|Frankiales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRD3_k127_1528271_0	1229780.BN381_10093	9.665e-184	589.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,3UWA6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRD3_k127_1544444_2	525909.Afer_0376	3.697e-118	402.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4CMT6@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRD3_k127_1544444_1	525909.Afer_0375	6.426e-167	539.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4CMUB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Protein synonym NADH dehydrogenase I subunit M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRD3_k127_1544444_0	1121877.JQKF01000009_gene572	4.637e-203	650.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4CMPU@84992|Acidimicrobiia	84992|Acidimicrobiia	CP	protein synonym multiple resistance and pH homeostasis protein A	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRD3_k127_1544444_3	1121877.JQKF01000009_gene573	2.574e-34	134.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4CN4N@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRD3_k127_1544444_4	1121877.JQKF01000009_gene574	2.354e-08	57.0	COG0839@1|root,COG0839@2|Bacteria,2GKRS@201174|Actinobacteria,4CN8Y@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRD3_k127_1561551_0	350054.Mflv_0425	2.768e-102	347.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,232KS@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome p450	-	-	1.14.15.14	ko:K20497	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
SRD3_k127_1561551_1	1122238.AULR01000018_gene203	1.377e-97	332.0	COG1672@1|root,COG1672@2|Bacteria,2GWBV@201174|Actinobacteria,4FMA0@85023|Microbacteriaceae	201174|Actinobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
SRD3_k127_1561551_3	2074.JNYD01000009_gene5334	9.492e-64	223.0	COG0346@1|root,COG0346@2|Bacteria,2IPA6@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD3_k127_1561551_2	136273.GY22_06920	5.678e-70	264.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,1W9FM@1268|Micrococcaceae	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRD3_k127_1571721_9	1449069.JMLO01000001_gene1588	1.245e-08	58.0	COG1993@1|root,COG1993@2|Bacteria,2IM7J@201174|Actinobacteria,4G1XZ@85025|Nocardiaceae	201174|Actinobacteria	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
SRD3_k127_1571721_1	1352941.M877_21370	2.492e-148	486.0	COG0477@1|root,COG0477@2|Bacteria,2GK8M@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_1571721_2	351607.Acel_1015	8.623e-131	432.0	COG0247@1|root,COG0247@2|Bacteria,2I3IR@201174|Actinobacteria,4EUJ2@85013|Frankiales	201174|Actinobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
SRD3_k127_1571721_6	595536.ADVE02000001_gene770	6.465e-46	171.0	COG0664@1|root,COG0664@2|Bacteria,1RII7@1224|Proteobacteria,2UA8E@28211|Alphaproteobacteria,37072@31993|Methylocystaceae	28211|Alphaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRD3_k127_1571721_4	518766.Rmar_2588	1.686e-83	293.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	asrB	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SRD3_k127_1571721_3	1449347.JQLN01000001_gene539	3.955e-105	346.0	COG1941@1|root,COG1941@2|Bacteria,2GSPN@201174|Actinobacteria,2M4QI@2063|Kitasatospora	201174|Actinobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
SRD3_k127_1571721_0	518766.Rmar_2590	1.585e-159	516.0	COG3259@1|root,COG3259@2|Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
SRD3_k127_1571721_8	1206730.BAGA01000174_gene2182	2.312e-22	109.0	COG0680@1|root,COG0680@2|Bacteria,2IJ3P@201174|Actinobacteria,4G2NH@85025|Nocardiaceae	201174|Actinobacteria	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
SRD3_k127_1571721_5	58123.JOFJ01000014_gene5035	1.171e-56	213.0	COG0697@1|root,COG0697@2|Bacteria,2IH82@201174|Actinobacteria	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRD3_k127_1571721_7	1121272.KB903290_gene4635	2.415e-24	118.0	29JD5@1|root,306AN@2|Bacteria,2I9J8@201174|Actinobacteria,4DKCX@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1576144_3	234267.Acid_6253	1.947e-10	72.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,NHL
SRD3_k127_1576144_0	1267535.KB906767_gene3159	0.0	1314.0	COG1201@1|root,COG1201@2|Bacteria,3Y348@57723|Acidobacteria,2JIVQ@204432|Acidobacteriia	204432|Acidobacteriia	L	dead deah	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRD3_k127_1576144_2	710686.Mycsm_01035	2.824e-30	128.0	2AUCB@1|root,31K05@2|Bacteria,2IK3D@201174|Actinobacteria,239I4@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRD3_k127_1576144_4	1217718.ALOU01000070_gene407	9.703e-06	55.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria	28216|Betaproteobacteria	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRD3_k127_1576144_1	298655.KI912266_gene6060	2.447e-72	262.0	COG0683@1|root,COG0683@2|Bacteria,2IBGV@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRD3_k127_1591228_0	649638.Trad_0076	6.788e-161	521.0	COG0138@1|root,COG0138@2|Bacteria,1WIVC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRD3_k127_1591228_1	1229780.BN381_130063	4.178e-100	355.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,3UWCI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRD3_k127_1591228_3	298655.KI912266_gene4207	2.3e-79	274.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRD3_k127_1591228_4	675635.Psed_4837	1.523e-22	112.0	COG3467@1|root,COG3467@2|Bacteria,2GQIA@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
SRD3_k127_1591228_5	1894.JOER01000017_gene4799	1.958e-20	106.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRD3_k127_1591228_2	1313172.YM304_07250	5.535e-81	278.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4CN4K@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRD3_k127_1591228_6	1519464.HY22_01095	9.282e-09	65.0	COG0538@1|root,COG0538@2|Bacteria	2|Bacteria	C	isocitrate dehydrogenase activity	icd	GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144	Iso_dh
SRD3_k127_1607350_1	1245469.S58_38650	5.733e-102	353.0	COG3468@1|root,COG3468@2|Bacteria,1QUZ3@1224|Proteobacteria,2U1BI@28211|Alphaproteobacteria,3JVY2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,TIG
SRD3_k127_1607350_7	743525.TSC_c03770	0.0005068	49.0	COG3462@1|root,COG3462@2|Bacteria,1WKPU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	-
SRD3_k127_1607350_4	1380390.JIAT01000010_gene4585	8.399e-44	164.0	2DMMQ@1|root,32SHK@2|Bacteria,2IHWW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
SRD3_k127_1607350_0	1123023.JIAI01000002_gene5486	9.802e-221	697.0	COG1350@1|root,COG1350@2|Bacteria,2GP7D@201174|Actinobacteria,4DZNN@85010|Pseudonocardiales	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD3_k127_1607350_2	1123024.AUII01000012_gene4221	5.557e-96	321.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria,4E188@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRD3_k127_1607350_3	1123401.JHYQ01000029_gene1985	3.772e-44	186.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,1RPW5@1236|Gammaproteobacteria,46151@72273|Thiotrichales	72273|Thiotrichales	H	PFAM UbiA prenyltransferase	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRD3_k127_1607350_6	298654.FraEuI1c_3604	5.03e-10	66.0	COG0748@1|root,COG0748@2|Bacteria,2HU2M@201174|Actinobacteria,4EWNH@85013|Frankiales	201174|Actinobacteria	P	coenzyme F420 binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1607350_5	525909.Afer_0450	2.332e-35	150.0	COG5650@1|root,COG5650@2|Bacteria,2I9AM@201174|Actinobacteria	201174|Actinobacteria	S	phosphatidylinositol metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1610009_3	525909.Afer_0364	7.717e-53	187.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4CMXA@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRD3_k127_1610009_4	525909.Afer_0363	9.74e-41	156.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,4CN51@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRD3_k127_1610009_0	1229780.BN381_450016	8.331e-141	465.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,3UX9K@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	FAD binding domain	menJ	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016491,GO:0016627,GO:0030312,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
SRD3_k127_1610009_5	1122138.AQUZ01000078_gene6137	1.188e-24	118.0	COG0791@1|root,COG0791@2|Bacteria,2IDIS@201174|Actinobacteria	201174|Actinobacteria	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,PG_binding_1
SRD3_k127_1610009_2	1246995.AFR_04305	4.816e-82	289.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1610009_1	525909.Afer_0253	1.623e-94	317.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4CMTZ@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD3_k127_1614912_9	377629.TERTU_0414	2.182e-05	49.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,1RYRV@1236|Gammaproteobacteria,2PQ3Q@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	M	Glycosyl transferase 4-like domain	gt4G	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD3_k127_1614912_6	1040983.AXAE01000019_gene3749	9.968e-21	107.0	COG1216@1|root,COG1216@2|Bacteria,1N5GE@1224|Proteobacteria,2UCJR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD3_k127_1614912_3	460265.Mnod_8763	4.108e-42	168.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	ko:K16648	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Methyltransf_11
SRD3_k127_1614912_1	929712.KI912613_gene3514	2.109e-76	277.0	COG0438@1|root,COG0438@2|Bacteria,2HEVG@201174|Actinobacteria,4CSMZ@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRD3_k127_1614912_10	441768.ACL_0241	0.000105	52.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRD3_k127_1614912_0	1313172.YM304_26510	2.63e-140	466.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	pks16	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008922,GO:0009058,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016877,GO:0016878,GO:0017076,GO:0019752,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0051704,GO:0070566,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	6.2.1.20	ko:K00666,ko:K01909	ko00071,map00071	-	R01406	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C,AMP-binding_C_2
SRD3_k127_1614912_7	1173024.KI912149_gene6192	4.896e-09	69.0	COG0110@1|root,COG0110@2|Bacteria,1G2PV@1117|Cyanobacteria,1JHR7@1189|Stigonemataceae	1117|Cyanobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,Hexapep,Hexapep_2
SRD3_k127_1614912_2	298654.FraEuI1c_2459	3.109e-51	201.0	COG0457@1|root,COG0457@2|Bacteria	298654.FraEuI1c_2459|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1614912_4	649638.Trad_0668	6.307e-37	151.0	COG0457@1|root,COG0457@2|Bacteria	649638.Trad_0668|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1614912_8	1089545.KB913037_gene1914	1.753e-07	64.0	COG2730@1|root,COG2730@2|Bacteria,2HW9X@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Cellulase
SRD3_k127_1614912_5	1449353.JQMQ01000005_gene3843	3.805e-22	104.0	COG0438@1|root,COG0438@2|Bacteria,2IBWR@201174|Actinobacteria,2NGZ3@228398|Streptacidiphilus	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD3_k127_1621929_5	1313172.YM304_10640	1.813e-120	406.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CMTI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRD3_k127_1621929_12	1122611.KB903996_gene7573	3.481e-32	138.0	COG0712@1|root,COG0712@2|Bacteria,2GMJ5@201174|Actinobacteria,4EG1R@85012|Streptosporangiales	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
SRD3_k127_1621929_15	1123023.JIAI01000013_gene3981	6.326e-21	100.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4E5ST@85010|Pseudonocardiales	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iNJ661.Rv1306	ATP-synt_B
SRD3_k127_1621929_14	351607.Acel_0648	4.442e-26	111.0	COG0636@1|root,COG0636@2|Bacteria,2IQZQ@201174|Actinobacteria,4EWJ5@85013|Frankiales	201174|Actinobacteria	C	ATP synthase subunit C	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0015988,GO:0015991,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iNJ661.Rv1305	ATP-synt_C
SRD3_k127_1621929_9	1298863.AUEP01000001_gene894	1.039e-51	199.0	COG0356@1|root,COG0356@2|Bacteria,2HY9H@201174|Actinobacteria,4DTV7@85009|Propionibacteriales	201174|Actinobacteria	C	ATP synthase A chain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_A
SRD3_k127_1621929_16	468556.AQYG01000051_gene2220	2.829e-08	63.0	29217@1|root,2ZPKF@2|Bacteria,2GPSM@201174|Actinobacteria,4GEN2@85026|Gordoniaceae	201174|Actinobacteria	S	ATP synthase I	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
SRD3_k127_1621929_6	525909.Afer_1804	2.652e-115	390.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4CMRB@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferase family 4	wecA	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRD3_k127_1621929_0	1313172.YM304_10550	9.69e-175	560.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4CMSU@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRD3_k127_1621929_10	1229780.BN381_10026	1.18e-49	180.0	COG0698@1|root,COG0698@2|Bacteria,2GKJG@201174|Actinobacteria,3UWPM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRD3_k127_1621929_4	931627.MycrhDRAFT_5800	3.838e-121	415.0	COG0183@1|root,COG0183@2|Bacteria,2I3PP@201174|Actinobacteria,232HJ@1762|Mycobacteriaceae	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
SRD3_k127_1621929_11	649743.HMPREF0972_02523	1.139e-33	147.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4D3PC@85005|Actinomycetales	201174|Actinobacteria	J	Belongs to the SUA5 family	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRD3_k127_1621929_8	1229780.BN381_10021	2.05e-53	201.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,3UWRW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
SRD3_k127_1621929_3	525909.Afer_1808	4.689e-133	433.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria,4CMPQ@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRD3_k127_1621929_13	525909.Afer_1810	3.482e-30	120.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4CP0K@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRD3_k127_1621929_1	469371.Tbis_0886	7.384e-155	507.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,4DX4E@85010|Pseudonocardiales	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRD3_k127_1621929_2	459495.SPLC1_S203740	1.137e-142	469.0	COG0498@1|root,COG0498@2|Bacteria,1G31E@1117|Cyanobacteria,1H8BC@1150|Oscillatoriales	1117|Cyanobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD3_k127_1621929_7	1229780.BN381_10012	9.492e-55	196.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,3UWE2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
SRD3_k127_1631250_5	1229780.BN381_80370	9.099e-50	191.0	COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria,3UWG7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRD3_k127_1631250_4	1430440.MGMSRv2_3492	2.616e-53	200.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2TRSG@28211|Alphaproteobacteria,2JPAY@204441|Rhodospirillales	204441|Rhodospirillales	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,His_biosynth
SRD3_k127_1631250_3	1229780.BN381_80369	1.17e-58	219.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,3UWJ0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRD3_k127_1631250_2	1229780.BN381_80368	5.252e-70	259.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,3UWJP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRD3_k127_1631250_1	1313172.YM304_22610	6.378e-118	407.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4CMYU@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRD3_k127_1631250_0	1229780.BN381_80362	1.182e-127	420.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,3UWFF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRD3_k127_1650423_0	1267533.KB906740_gene214	4.245e-170	552.0	COG0058@1|root,COG0058@2|Bacteria,3Y65H@57723|Acidobacteria,2JM98@204432|Acidobacteriia	204432|Acidobacteriia	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
SRD3_k127_1650423_1	525368.HMPREF0591_4224	1.212e-92	315.0	COG0028@1|root,COG0028@2|Bacteria,2GJ20@201174|Actinobacteria,232SJ@1762|Mycobacteriaceae	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	-	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRD3_k127_1663872_0	1089544.KB912942_gene1571	8.428e-146	469.0	COG0446@1|root,COG0446@2|Bacteria,2GRTN@201174|Actinobacteria,4E527@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DsrC,Pyr_redox_2
SRD3_k127_1663872_4	101510.RHA1_ro11235	4.049e-34	134.0	COG0599@1|root,COG0599@2|Bacteria,2IRPW@201174|Actinobacteria,4G1W2@85025|Nocardiaceae	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRD3_k127_1663872_1	1229780.BN381_10323	9.085e-119	389.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,3UWV5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SRD3_k127_1663872_2	35754.JNYJ01000089_gene6361	3.174e-75	269.0	COG0642@1|root,COG2205@2|Bacteria,2I2QY@201174|Actinobacteria,4DHBZ@85008|Micromonosporales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRD3_k127_1663872_3	35754.JNYJ01000089_gene6360	1.657e-71	264.0	COG0745@1|root,COG0745@2|Bacteria,2I8R2@201174|Actinobacteria,4DHJ4@85008|Micromonosporales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRD3_k127_1699096_1	977880.RALTA_A2365	2.551e-16	89.0	COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,2VV0C@28216|Betaproteobacteria,1K13R@119060|Burkholderiaceae	28216|Betaproteobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD3_k127_1699096_0	983917.RGE_10840	8.169e-58	223.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,2VKTV@28216|Betaproteobacteria,1KJ7H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRD3_k127_1711498_8	1229780.BN381_350093	7.105e-15	74.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,3UWHR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRD3_k127_1711498_6	106370.Francci3_2015	3.375e-29	123.0	COG1846@1|root,COG1846@2|Bacteria,2IFRN@201174|Actinobacteria,4EWUI@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRD3_k127_1711498_0	258052.JNYV01000002_gene1292	3.266e-135	447.0	COG0477@1|root,COG0477@2|Bacteria,2IBIG@201174|Actinobacteria,2M2FQ@2063|Kitasatospora	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_1711498_7	195250.CM001776_gene1926	1.05e-24	112.0	COG1247@1|root,COG1247@2|Bacteria,1G64C@1117|Cyanobacteria,1H1UD@1129|Synechococcus	1117|Cyanobacteria	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD3_k127_1711498_1	58344.JOEL01000023_gene1106	1.489e-129	433.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria	201174|Actinobacteria	T	2-nitropropane dioxygenase	fabK	GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0007623,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0012505,GO:0016192,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034404,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0042278,GO:0042451,GO:0042455,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046903,GO:0048511,GO:0050896,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097708,GO:0099503,GO:0101002,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1904813	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
SRD3_k127_1711498_4	1343740.M271_44245	4.25e-104	349.0	COG2057@1|root,COG2057@2|Bacteria,2GMA1@201174|Actinobacteria	201174|Actinobacteria	I	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CoA_trans
SRD3_k127_1711498_2	43354.JOIJ01000029_gene3414	1.638e-115	385.0	COG1788@1|root,COG1788@2|Bacteria,2GK61@201174|Actinobacteria,4DX73@85010|Pseudonocardiales	201174|Actinobacteria	I	Coenzyme A transferase	gctA	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRD3_k127_1711498_3	469383.Cwoe_2352	1.715e-104	346.0	COG1024@1|root,COG1024@2|Bacteria,2GN54@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA20	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD3_k127_1711498_5	1245471.PCA10_13800	5.949e-85	288.0	COG1028@1|root,COG1028@2|Bacteria,1P1U4@1224|Proteobacteria,1RR3M@1236|Gammaproteobacteria,1YJ2B@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD3_k127_1724349_1	1229780.BN381_150040	2.088e-129	422.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,3UWAK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRD3_k127_1724349_4	1229780.BN381_70125	1.047e-46	176.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,3UWQX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRD3_k127_1724349_2	1313172.YM304_05650	7.506e-70	249.0	COG1624@1|root,COG1624@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	CP_0674	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N,PTS_EIIA_2
SRD3_k127_1724349_6	443218.AS9A_1709	2.177e-25	108.0	COG1846@1|root,COG1846@2|Bacteria,2IMGG@201174|Actinobacteria,23APA@1762|Mycobacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_24,MarR_2
SRD3_k127_1724349_5	675635.Psed_3135	6.855e-36	145.0	2AEJC@1|root,314EV@2|Bacteria,2GMTI@201174|Actinobacteria,4E3QP@85010|Pseudonocardiales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRD3_k127_1724349_3	1120948.KB903230_gene4922	1.358e-51	189.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria	201174|Actinobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRD3_k127_1724349_0	1123065.ATWL01000018_gene2119	2.264e-207	673.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria	201174|Actinobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRD3_k127_1733582_1	367299.JOEE01000001_gene1564	1.556e-19	93.0	COG1984@1|root,COG1984@2|Bacteria,2GITH@201174|Actinobacteria,4FGH8@85021|Intrasporangiaceae	201174|Actinobacteria	E	Allophanate hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B,CT_C_D
SRD3_k127_1733582_0	1463879.JOHP01000029_gene4895	9.201e-60	218.0	COG5483@1|root,COG5483@2|Bacteria,2IHSH@201174|Actinobacteria	201174|Actinobacteria	L	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRD3_k127_1733582_2	298653.Franean1_2231	9.656e-11	67.0	2DQZQ@1|root,339JR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1733582_3	1211815.CBYP010000014_gene3478	2.749e-08	66.0	COG0530@1|root,COG0530@2|Bacteria,2GJR3@201174|Actinobacteria,4EVE7@85013|Frankiales	201174|Actinobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRD3_k127_1733582_4	378806.STAUR_3434	8.278e-06	48.0	COG5592@1|root,COG5592@2|Bacteria,1RI8J@1224|Proteobacteria,42XM7@68525|delta/epsilon subdivisions,2WSTY@28221|Deltaproteobacteria,2YWYZ@29|Myxococcales	28221|Deltaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRD3_k127_1747933_2	479435.Kfla_5685	6.992e-44	162.0	COG0242@1|root,COG0242@2|Bacteria,2HMJS@201174|Actinobacteria,4DNQP@85009|Propionibacteriales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRD3_k127_1747933_0	1229780.BN381_100013	2.876e-98	326.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,3UXE8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRD3_k127_1747933_1	66874.JOFS01000034_gene536	2.532e-87	298.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria	201174|Actinobacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C
SRD3_k127_1751378_9	1313172.YM304_27520	1.141e-16	81.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CN5T@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRD3_k127_1751378_2	1120936.KB907209_gene1795	2.798e-121	410.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4EMZ3@85012|Streptosporangiales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD3_k127_1751378_4	351607.Acel_1832	3.623e-84	311.0	COG0745@1|root,COG0745@2|Bacteria,2GJRR@201174|Actinobacteria,4ESGE@85013|Frankiales	201174|Actinobacteria	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRD3_k127_1751378_1	351607.Acel_1831	4.268e-123	413.0	COG0642@1|root,COG2205@2|Bacteria,2GK1J@201174|Actinobacteria,4ERY7@85013|Frankiales	201174|Actinobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRD3_k127_1751378_10	351607.Acel_1830	7.577e-15	87.0	COG5401@1|root,COG5401@2|Bacteria,2IRGJ@201174|Actinobacteria	201174|Actinobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
SRD3_k127_1751378_8	1313172.YM304_26740	5.791e-25	111.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4CN96@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRD3_k127_1751378_6	1313172.YM304_26760	3.764e-51	189.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4CN49@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRD3_k127_1751378_3	1313172.YM304_41020	5.662e-93	314.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4CNUE@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_1751378_0	1313172.YM304_26780	1.328e-203	655.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria,4CMTE@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Class-II DAHP synthetase family	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
SRD3_k127_1751378_5	1246995.AFR_04305	1.102e-80	288.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1751378_11	408672.NBCG_05361	2.841e-09	70.0	COG3064@1|root,COG3064@2|Bacteria,2I655@201174|Actinobacteria,4DSYQ@85009|Propionibacteriales	201174|Actinobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1751378_7	1172188.KB911825_gene3539	3.172e-27	123.0	2F8QP@1|root,3412Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1763525_7	314230.DSM3645_08962	2.258e-26	115.0	COG4398@1|root,COG4398@2|Bacteria,2IXYT@203682|Planctomycetes	203682|Planctomycetes	S	PFAM FIST C domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRD3_k127_1763525_9	405948.SACE_1886	4.545e-13	80.0	COG2050@1|root,COG2050@2|Bacteria,2IJ48@201174|Actinobacteria,4E5BE@85010|Pseudonocardiales	201174|Actinobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRD3_k127_1763525_10	1313172.YM304_26170	1.931e-12	72.0	28R1E@1|root,2ZDG1@2|Bacteria,2HDQB@201174|Actinobacteria,4CNE2@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRD3_k127_1763525_5	1229780.BN381_410006	8.433e-86	295.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,3UWFZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
SRD3_k127_1763525_6	1121877.JQKF01000002_gene1617	8.369e-30	138.0	COG1141@1|root,COG1141@2|Bacteria,2IKKX@201174|Actinobacteria,4CN8X@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_15
SRD3_k127_1763525_0	525909.Afer_0907	6.511e-262	818.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4CMRU@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Proteasomal ATPase OB/ID domain	arc	-	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
SRD3_k127_1763525_2	1313172.YM304_26070	2.657e-201	637.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4CMSZ@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pup-ligase protein	dop	-	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
SRD3_k127_1763525_8	1121877.JQKF01000002_gene1620	3.36e-15	77.0	2E9C2@1|root,333JS@2|Bacteria,2HGHP@201174|Actinobacteria,4CNEV@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation	pup	-	-	ko:K13570	-	-	-	-	ko00000,ko04121	-	-	-	Pup
SRD3_k127_1763525_4	1229780.BN381_400043	7.617e-95	341.0	COG0638@1|root,COG0638@2|Bacteria,2GJ60@201174|Actinobacteria,3UX89@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Proteasome subunit	prcB	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRD3_k127_1763525_3	1121877.JQKF01000002_gene1622	3.928e-97	321.0	COG0638@1|root,COG0638@2|Bacteria,2GKZ1@201174|Actinobacteria,4CMY5@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcA	-	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRD3_k127_1763525_1	1313172.YM304_26020	1.498e-233	729.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4CMS0@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	-	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
SRD3_k127_1776264_5	1120950.KB892746_gene3534	1.799e-37	152.0	COG1122@1|root,COG1122@2|Bacteria,2GMK1@201174|Actinobacteria,4DQPM@85009|Propionibacteriales	201174|Actinobacteria	P	ECF transporter, substrate-specific component	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF_trnsprt
SRD3_k127_1776264_3	479434.Sthe_0926	4.622e-74	276.0	COG1122@1|root,COG1122@2|Bacteria,2G5RY@200795|Chloroflexi,27XTB@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SRD3_k127_1776264_7	635013.TherJR_1258	1.023e-08	68.0	COG0619@1|root,COG0619@2|Bacteria,1TSB5@1239|Firmicutes,24AN7@186801|Clostridia,2616E@186807|Peptococcaceae	186801|Clostridia	P	PFAM Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
SRD3_k127_1776264_8	1385519.N801_07715	3.151e-06	58.0	COG1657@1|root,COG1657@2|Bacteria,2IAB9@201174|Actinobacteria,4FH5Z@85021|Intrasporangiaceae	201174|Actinobacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1776264_0	101510.RHA1_ro01589	6e-168	540.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4FV6F@85025|Nocardiaceae	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRD3_k127_1776264_6	1121272.KB903293_gene7135	5.092e-12	72.0	COG0582@1|root,COG0582@2|Bacteria,2I2P9@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
SRD3_k127_1776264_4	66875.JODY01000006_gene2236	1.226e-68	239.0	COG0500@1|root,COG2226@2|Bacteria,2I3AK@201174|Actinobacteria	201174|Actinobacteria	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRD3_k127_1776264_2	994479.GL877882_gene6853	5.544e-114	380.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4DXF2@85010|Pseudonocardiales	201174|Actinobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.2.3,1.1.3.46	ko:K00101,ko:K16422	ko00261,ko00620,ko01055,ko01100,ko01130,map00261,map00620,map01055,map01100,map01130	-	R00196,R06633	RC00044,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRD3_k127_1776264_1	68260.JOAY01000001_gene3793	1.751e-129	430.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
SRD3_k127_1781301_1	471852.Tcur_1271	7.721e-110	359.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4EGX0@85012|Streptosporangiales	201174|Actinobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRD3_k127_1781301_0	1380390.JIAT01000010_gene3879	5.665e-170	536.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CSGY@84995|Rubrobacteria	84995|Rubrobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRD3_k127_1781301_2	1463825.JNXC01000007_gene789	8.716e-107	379.0	COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4DYVV@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
SRD3_k127_1781301_3	298653.Franean1_5788	7.931e-73	248.0	COG2514@1|root,COG2514@2|Bacteria,2GUZK@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRD3_k127_1781301_4	1136417.AZWE01000018_gene968	1.145e-33	140.0	COG2267@1|root,COG2267@2|Bacteria,2H3BR@201174|Actinobacteria,4DHTZ@85008|Micromonosporales	201174|Actinobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_178212_2	219305.MCAG_04136	6.774e-58	213.0	COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,4DAAF@85008|Micromonosporales	201174|Actinobacteria	P	ABC transporter	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRD3_k127_178212_3	42256.RradSPS_0876	4.586e-10	69.0	297P3@1|root,2ZUW0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_178212_1	266117.Rxyl_0964	1.231e-146	491.0	COG1035@1|root,COG2878@1|root,COG1035@2|Bacteria,COG2878@2|Bacteria,2GRHK@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4_9,FrhB_FdhB_C,FrhB_FdhB_N
SRD3_k127_178212_0	266117.Rxyl_0963	7.303e-238	747.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4CQKT@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.7.1,1.8.1.2	ko:K00366,ko:K00381	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRD3_k127_1783180_1	1051632.TPY_0244	8.579e-73	272.0	COG0531@1|root,COG0531@2|Bacteria,1UW5Y@1239|Firmicutes	1239|Firmicutes	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRD3_k127_1783180_2	1121422.AUMW01000010_gene1045	2.98e-17	96.0	COG3255@1|root,COG3255@2|Bacteria,1V88A@1239|Firmicutes,24KTK@186801|Clostridia,26268@186807|Peptococcaceae	186801|Clostridia	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRD3_k127_1783180_0	1463853.JOHW01000006_gene4426	3.727e-128	424.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria	201174|Actinobacteria	E	(mono)amine oxidase	aofH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRD3_k127_1793782_1	570268.ANBB01000059_gene4218	0.0002686	54.0	COG3170@1|root,COG3170@2|Bacteria,2GN00@201174|Actinobacteria,4EFQZ@85012|Streptosporangiales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1793782_0	525909.Afer_0027	5.21e-93	330.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CN0A@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRD3_k127_1801155_0	710685.MycrhN_0661	2.585e-37	144.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,2363K@1762|Mycobacteriaceae	201174|Actinobacteria	G	Belongs to the FGGY kinase family	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRD3_k127_1801155_2	525368.HMPREF0591_3836	6.496e-22	96.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,2363K@1762|Mycobacteriaceae	201174|Actinobacteria	G	Belongs to the FGGY kinase family	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRD3_k127_1801155_3	868131.MSWAN_2292	1.647e-06	58.0	COG0599@1|root,arCOG02151@2157|Archaea,2Y0SW@28890|Euryarchaeota	28890|Euryarchaeota	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRD3_k127_1801155_1	298654.FraEuI1c_3299	1.007e-23	108.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	ydgC	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD3_k127_1823255_4	1313172.YM304_27060	7.869e-27	109.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CMRW@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRD3_k127_1823255_0	525909.Afer_0653	9.561e-102	336.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CMRW@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRD3_k127_1823255_3	1122604.JONR01000003_gene1577	6.022e-37	145.0	COG2128@1|root,COG2128@2|Bacteria,1N8NE@1224|Proteobacteria,1T0ZK@1236|Gammaproteobacteria,1XA8E@135614|Xanthomonadales	135614|Xanthomonadales	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRD3_k127_1823255_1	1125971.ASJB01000042_gene3615	2.456e-67	245.0	COG1670@1|root,COG1670@2|Bacteria,2IFMK@201174|Actinobacteria,4E3F3@85010|Pseudonocardiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.57,2.3.1.82	ko:K00657,ko:K00663	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_8
SRD3_k127_1823255_2	525909.Afer_1400	1.473e-66	240.0	COG1470@1|root,COG1470@2|Bacteria,2GP8D@201174|Actinobacteria,4CN8S@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRD3_k127_184764_1	1313172.YM304_02760	6.425e-50	200.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRD3_k127_184764_0	1206731.BAGB01000025_gene3156	4.081e-68	248.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4FYUQ@85025|Nocardiaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRD3_k127_184764_2	67356.KL575616_gene8534	8.927e-33	131.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria	201174|Actinobacteria	C	CoA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRD3_k127_1851928_0	357808.RoseRS_2677	4.501e-49	193.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2G8PX@200795|Chloroflexi,376RK@32061|Chloroflexia	32061|Chloroflexia	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_2
SRD3_k127_1851928_1	1463921.JODF01000015_gene7110	3.256e-34	143.0	COG2520@1|root,COG2520@2|Bacteria,2I388@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRD3_k127_1851928_2	1380347.JNII01000007_gene386	2.741e-13	82.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4ERZZ@85013|Frankiales	201174|Actinobacteria	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
SRD3_k127_1863191_3	670487.Ocepr_0136	2.943e-14	76.0	COG1912@1|root,COG1912@2|Bacteria,1WIIQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRD3_k127_1863191_4	408672.NBCG_00988	4.585e-13	79.0	COG3311@1|root,COG3311@2|Bacteria,2GQGV@201174|Actinobacteria,4DS39@85009|Propionibacteriales	201174|Actinobacteria	K	Helix-turn-helix domain	xis	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRD3_k127_1863191_0	1229780.BN381_60047	1.579e-64	233.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,3UWS1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRD3_k127_1863191_2	1313172.YM304_37890	7.656e-32	133.0	2AZ39@1|root,31R9K@2|Bacteria,2GMCY@201174|Actinobacteria	201174|Actinobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
SRD3_k127_1863191_1	1313172.YM304_37900	1.869e-35	139.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4CMYV@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferase 4-like domain	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD3_k127_1867686_2	298655.KI912266_gene5748	2.632e-39	152.0	COG2030@1|root,COG2030@2|Bacteria,2IGBP@201174|Actinobacteria	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRD3_k127_1867686_0	471852.Tcur_2177	3.973e-220	709.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4EFXA@85012|Streptosporangiales	201174|Actinobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_1867686_4	1394178.AWOO02000002_gene1812	6.867e-14	85.0	COG0789@1|root,COG0789@2|Bacteria,2GKAU@201174|Actinobacteria,4EP7I@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRD3_k127_1867686_1	1157635.KB892017_gene1641	5.638e-58	205.0	2F10Q@1|root,33U29@2|Bacteria,2IFMM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SRD3_k127_1867686_3	931627.MycrhDRAFT_1216	3.864e-33	134.0	COG2030@1|root,COG2030@2|Bacteria,2IKE4@201174|Actinobacteria	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRD3_k127_186847_0	1121877.JQKF01000004_gene1119	2.125e-156	501.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4CMSF@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,S1
SRD3_k127_186847_1	1206743.BAGM01000092_gene4730	7.05e-52	196.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4FWB3@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the peptidase M16 family	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRD3_k127_1874016_0	1229780.BN381_10205	6.254e-135	447.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,3UWAZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Phosphohydrolase-associated domain	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRD3_k127_1874016_3	525909.Afer_0348	1.543e-14	85.0	2E3M2@1|root,31DE4@2|Bacteria,2HH0X@201174|Actinobacteria,4CP16@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF3107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3107
SRD3_k127_1874016_1	1229780.BN381_310065	9.243e-69	250.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria	201174|Actinobacteria	D	Pfam Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRD3_k127_1874024_2	452652.KSE_34510	2.157e-73	256.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,2M1FT@2063|Kitasatospora	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD3_k127_1874024_0	525904.Tter_2663	6.153e-116	389.0	COG2059@1|root,COG2059@2|Bacteria,2NPUT@2323|unclassified Bacteria	2|Bacteria	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRD3_k127_1874024_1	1313172.YM304_05030	1.259e-84	286.0	COG1051@1|root,COG1051@2|Bacteria,2HG6C@201174|Actinobacteria,4CN3B@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Hydrolase of X-linked nucleoside diphosphate N terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N
SRD3_k127_1874024_4	1313172.YM304_14750	0.0002263	49.0	2FF8Q@1|root,3476J@2|Bacteria,2H7PN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1874024_3	1229780.BN381_50095	1.255e-60	221.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria	201174|Actinobacteria	K	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRD3_k127_1875744_1	1313172.YM304_27690	3.655e-54	197.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4CNBV@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRD3_k127_1875744_0	105420.BBPO01000011_gene1919	2.926e-95	321.0	COG1024@1|root,COG1024@2|Bacteria,2GJY4@201174|Actinobacteria,2NF6J@228398|Streptacidiphilus	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD3_k127_1878358_0	1463885.KL578379_gene6093	5.286e-93	320.0	COG2017@1|root,COG3265@1|root,COG2017@2|Bacteria,COG3265@2|Bacteria,2GJ0H@201174|Actinobacteria	201174|Actinobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim,SKI
SRD3_k127_1878358_2	1449346.JQMO01000003_gene2401	9.937e-46	177.0	COG0496@1|root,COG0496@2|Bacteria,2IFAX@201174|Actinobacteria,2M5E3@2063|Kitasatospora	201174|Actinobacteria	S	Survival protein SurE	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRD3_k127_1878358_3	298655.KI912266_gene1399	7.637e-32	131.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K21687	-	-	-	-	ko00000	-	GH23	-	Glucosaminidase,PG_binding_1,Transglycosylas
SRD3_k127_1878358_1	713587.THITH_03465	4.192e-63	226.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,DLH,Peptidase_S9
SRD3_k127_1882322_0	1313172.YM304_09730	2.535e-115	386.0	COG0489@1|root,COG2151@1|root,COG0489@2|Bacteria,COG2151@2|Bacteria,2GJUZ@201174|Actinobacteria,4CMV4@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
SRD3_k127_1882322_1	1385519.N801_04575	2.481e-38	155.0	COG1309@1|root,COG1309@2|Bacteria,2HQXF@201174|Actinobacteria,4FHR9@85021|Intrasporangiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD3_k127_1882322_2	525909.Afer_0540	2.712e-05	53.0	COG1898@1|root,COG1898@2|Bacteria,2HG63@201174|Actinobacteria,4CN7N@84992|Acidimicrobiia	84992|Acidimicrobiia	M	dTDP-4-dehydrorhamnose 3,5-epimerase	rmlC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRD3_k127_1883162_1	1128421.JAGA01000001_gene2399	2.627e-72	252.0	COG0179@1|root,COG0179@2|Bacteria	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN746.PP_4620	FAA_hydrolase,FAA_hydrolase_N
SRD3_k127_1883162_0	570268.ANBB01000041_gene1635	4.274e-136	448.0	COG3508@1|root,COG3508@2|Bacteria,2GKZV@201174|Actinobacteria,4EHDH@85012|Streptosporangiales	201174|Actinobacteria	Q	homogentisate 1,2-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRD3_k127_1883162_3	1265310.CCBD010000031_gene1747	2.041e-47	184.0	COG2128@1|root,COG2128@2|Bacteria,2IAC5@201174|Actinobacteria,236CM@1762|Mycobacteriaceae	201174|Actinobacteria	S	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRD3_k127_1883162_2	419947.MRA_1542	2.553e-53	192.0	COG1063@1|root,COG1063@2|Bacteria,2GKBE@201174|Actinobacteria,236FJ@1762|Mycobacteriaceae	201174|Actinobacteria	C	alcohol dehydrogenase	adh	-	1.1.1.1,1.1.1.14	ko:K00001,ko:K00008	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	M00014	R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_1887493_5	211114.JOEF01000006_gene2542	1.597e-13	72.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4E4JX@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_1887493_2	880073.Calab_0133	3.035e-39	167.0	COG0860@1|root,COG1361@1|root,COG3858@1|root,COG0860@2|Bacteria,COG1361@2|Bacteria,COG3858@2|Bacteria,2NQII@2323|unclassified Bacteria	2|Bacteria	M	Glyco_18	-	-	3.4.17.14,3.5.1.28	ko:K01448,ko:K07260,ko:K20276	ko00550,ko01100,ko01502,ko01503,ko02020,ko02024,map00550,map01100,map01502,map01503,map02020,map02024	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036	-	-	-	Amidase_3,CHAP,CW_binding_2,Cu_amine_oxidN1,GBS_Bsp-like,Glyco_hydro_18,Glyco_hydro_25,Peptidase_C39_2,SH3_5,VanY,YSIRK_signal
SRD3_k127_1887493_3	1313172.YM304_14800	2.879e-32	136.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRD3_k127_1887493_1	1121877.JQKF01000007_gene981	9.598e-74	257.0	COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Fatty acid desaturase	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRD3_k127_1887493_6	1203605.HMPREF1531_01727	2.2e-12	75.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4DRN7@85009|Propionibacteriales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB2	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRD3_k127_1887493_0	1122237.AUGQ01000002_gene1898	9.419e-82	282.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4FR7P@85023|Microbacteriaceae	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	yeaC	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRD3_k127_1887493_7	1121385.AQXW01000004_gene1430	0.000156	55.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,1ZW9C@145357|Dermacoccaceae	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRD3_k127_1887493_4	1173028.ANKO01000090_gene3501	3.832e-25	123.0	COG1305@1|root,COG1305@2|Bacteria,1FZW2@1117|Cyanobacteria,1H7X1@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Transglutaminase-like superfamily	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
SRD3_k127_1911539_2	645465.ACUR01000520_gene4059	3.877e-44	166.0	COG0500@1|root,COG0518@1|root,COG0518@2|Bacteria,COG2226@2|Bacteria,2GNA6@201174|Actinobacteria	201174|Actinobacteria	F	glutamine amidotransferase	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,Methyltransf_11
SRD3_k127_1911539_1	1205910.B005_0122	2.754e-66	235.0	COG1842@1|root,COG1842@2|Bacteria,2GP0K@201174|Actinobacteria,4EGYB@85012|Streptosporangiales	201174|Actinobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRD3_k127_1911539_5	1089544.KB912942_gene1647	3.671e-11	76.0	2DS25@1|root,33E6E@2|Bacteria,2I8BZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1911539_3	208444.JNYY01000012_gene7789	5.123e-39	168.0	2DQY4@1|root,339C4@2|Bacteria,2GP83@201174|Actinobacteria,4EDXZ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1911539_0	1313172.YM304_40560	1.288e-83	287.0	COG2141@1|root,COG2141@2|Bacteria,2GJ3B@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase, MSMEG_3544 family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_1911539_4	426117.M446_1028	1.515e-13	79.0	COG3832@1|root,COG3832@2|Bacteria,1REDB@1224|Proteobacteria,2UADQ@28211|Alphaproteobacteria,1JZHW@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRD3_k127_1911539_6	487521.OCU_25960	9.315e-10	62.0	COG3832@1|root,COG3832@2|Bacteria,2IH7G@201174|Actinobacteria,23908@1762|Mycobacteriaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRD3_k127_1920250_2	1121877.JQKF01000040_gene1861	1.96e-73	255.0	COG2890@1|root,COG2890@2|Bacteria,2GNC1@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRD3_k127_1920250_5	100226.SCO6092	1.664e-35	145.0	COG3797@1|root,COG3797@2|Bacteria,2GPDB@201174|Actinobacteria	201174|Actinobacteria	I	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRD3_k127_1920250_3	926550.CLDAP_13200	7.215e-44	175.0	COG1253@1|root,COG1253@2|Bacteria,2G6D1@200795|Chloroflexi	200795|Chloroflexi	S	CBS domain containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRD3_k127_1920250_6	1313172.YM304_41120	8.624e-31	128.0	COG0745@1|root,COG0745@2|Bacteria	1313172.YM304_41120|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1920250_0	1229780.BN381_100120	5.429e-107	377.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria,3UX1R@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRD3_k127_1920250_1	1229780.BN381_100119	9.804e-86	296.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,3UXHX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRD3_k127_1920250_7	1229780.BN381_100117	1.634e-27	113.0	2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,3UWYX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB3	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRD3_k127_1920250_4	105425.BBPL01000059_gene5044	1.85e-37	151.0	arCOG03842@1|root,30WW9@2|Bacteria,2IDJ1@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF929
SRD3_k127_1921534_0	487521.OCU_19830	1.079e-75	262.0	COG0330@1|root,COG0330@2|Bacteria,2GKFP@201174|Actinobacteria,2349A@1762|Mycobacteriaceae	201174|Actinobacteria	O	SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRD3_k127_1921534_2	429009.Adeg_0306	8.168e-49	180.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,42G1V@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRD3_k127_1921534_1	106370.Francci3_1507	3.684e-67	235.0	COG1651@1|root,COG1651@2|Bacteria,2IT6U@201174|Actinobacteria	201174|Actinobacteria	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRD3_k127_1931911_1	1313172.YM304_07800	7.569e-54	214.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4CNC4@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pfam:Zinicin_2	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRD3_k127_1931911_2	1194972.MVAC_25670	4.536e-18	98.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,237YT@1762|Mycobacteriaceae	201174|Actinobacteria	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRD3_k127_1931911_0	1313172.YM304_09040	3.94e-119	396.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CMUQ@84992|Acidimicrobiia	201174|Actinobacteria	D	Cell division protein FtsA	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRD3_k127_1932947_1	1463861.JNXE01000001_gene5183	1.572e-45	172.0	2BZNP@1|root,30717@2|Bacteria,2IAEK@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2889)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2889
SRD3_k127_1932947_0	298653.Franean1_5198	8.245e-65	230.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria,4EVCG@85013|Frankiales	201174|Actinobacteria	S	Bacterial transferase hexapeptide (six repeats)	gca	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep
SRD3_k127_1933505_1	1321773.HMPREF9069_00911	9.9e-12	72.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria,4CUGP@84998|Coriobacteriia	84998|Coriobacteriia	EI	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRD3_k127_1933505_0	1205680.CAKO01000010_gene3801	9.826e-140	471.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2U2SV@28211|Alphaproteobacteria,2JZPJ@204441|Rhodospirillales	28211|Alphaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRD3_k127_1934751_0	1229780.BN381_50149	2.959e-89	305.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,3UWCS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRD3_k127_1934751_3	525909.Afer_1694	3.328e-18	94.0	COG1758@1|root,COG1758@2|Bacteria,2HG9P@201174|Actinobacteria,4CN82@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRD3_k127_1934751_1	1313172.YM304_20490	4.431e-59	210.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4CN5V@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Guanylate kinase homologues.	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRD3_k127_1934751_2	525909.Afer_1696	5.066e-36	143.0	COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria,4CN68@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Helix-hairpin-helix DNA-binding motif class 1	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1934751_4	1229780.BN381_50146	1.993e-12	68.0	COG0284@1|root,COG0284@2|Bacteria,2HPEA@201174|Actinobacteria,3UXRN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRD3_k127_1936378_8	317655.Sala_0875	6.66e-10	63.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TTRD@28211|Alphaproteobacteria,2K16D@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_1936378_1	1123320.KB889689_gene530	1.995e-157	516.0	COG0318@1|root,COG0318@2|Bacteria,2GKZ6@201174|Actinobacteria	201174|Actinobacteria	IQ	synthetase	fadD17	GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0032787,GO:0042546,GO:0042759,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0072330,GO:1901576	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_1936378_4	469383.Cwoe_3934	1.564e-69	258.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria,4CRE1@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K04116	ko00362,ko01120,map00362,map01120	M00540	R05620	RC00004,RC01438	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_1936378_5	298655.KI912266_gene2716	3.353e-60	222.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4EU2D@85013|Frankiales	201174|Actinobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_1936378_2	13690.CP98_00468	1.169e-104	367.0	COG1960@1|root,COG1960@2|Bacteria,1P8I7@1224|Proteobacteria,2U0AW@28211|Alphaproteobacteria,2K1N3@204457|Sphingomonadales	204457|Sphingomonadales	C	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_1936378_6	1463854.JOHT01000006_gene6751	1.62e-58	214.0	COG1024@1|root,COG1024@2|Bacteria,2GKNU@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD3_k127_1936378_3	1268622.AVS7_04325	1.144e-102	359.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHB0@28216|Betaproteobacteria,4AAPD@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRD3_k127_1936378_0	47839.CCAU010000004_gene1016	2.513e-177	565.0	COG1063@1|root,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria,23300@1762|Mycobacteriaceae	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_1936378_7	298654.FraEuI1c_3299	3.869e-12	79.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	ydgC	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD3_k127_195290_1	929712.KI912613_gene3514	2.495e-56	214.0	COG0438@1|root,COG0438@2|Bacteria,2HEVG@201174|Actinobacteria,4CSMZ@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRD3_k127_195290_2	1504823.CCMM01000012_gene1837	2.444e-27	124.0	COG1682@1|root,COG1682@2|Bacteria,2NQ2H@2323|unclassified Bacteria	2|Bacteria	U	ABC-2 type transporter	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
SRD3_k127_195290_0	435830.HMPREF0045_00831	7.818e-75	266.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4D3DP@85005|Actinomycetales	201174|Actinobacteria	GM	ABC transporter, ATP-binding protein	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRD3_k127_1993738_4	1313172.YM304_19730	2.391e-16	94.0	COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4CN4U@84992|Acidimicrobiia	84992|Acidimicrobiia	FG	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRD3_k127_1993738_0	365528.KB891223_gene1314	2.032e-241	762.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4ES1K@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
SRD3_k127_1993738_1	1229780.BN381_50169	1.095e-162	520.0	COG0215@1|root,COG0215@2|Bacteria,2GJZR@201174|Actinobacteria,3UX20@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	tRNA synthetases class I (C) catalytic domain	mshC	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
SRD3_k127_1993738_3	1229780.BN381_50168	9.725e-50	184.0	COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria	201174|Actinobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	npdG	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRD3_k127_1993738_2	1313172.YM304_19680	5.964e-105	359.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria,4CMWN@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD3_k127_1993744_5	1121877.JQKF01000009_gene542	5.62e-10	63.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4CMU9@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRD3_k127_1993744_0	1121877.JQKF01000009_gene541	1.01e-66	234.0	COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria,4CN0S@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRD3_k127_1993744_4	1172185.KB911531_gene3457	1.189e-12	76.0	COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria,4G2ZP@85025|Nocardiaceae	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRD3_k127_1993744_2	1464048.JNZS01000005_gene5561	3.322e-31	124.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4DEU7@85008|Micromonosporales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRD3_k127_1993744_1	525909.Afer_0408	6.908e-66	227.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CMZN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRD3_k127_1993744_3	525909.Afer_0409	7.289e-30	124.0	COG0198@1|root,COG0198@2|Bacteria,2HGDN@201174|Actinobacteria,4CNBW@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRD3_k127_1994606_5	68194.JNXR01000017_gene7536	1.467e-10	68.0	COG5650@1|root,COG5650@2|Bacteria,2I9AM@201174|Actinobacteria	201174|Actinobacteria	S	phosphatidylinositol metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_1994606_0	1306990.BARG01000052_gene6108	5.006e-229	730.0	COG2409@1|root,COG2409@2|Bacteria,2HU5I@201174|Actinobacteria	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRD3_k127_1994606_4	748247.AZKH_2910	2.179e-13	78.0	COG1846@1|root,COG1846@2|Bacteria,1N7PQ@1224|Proteobacteria,2VV8Y@28216|Betaproteobacteria,2KWY8@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRD3_k127_1994606_1	591167.Sfla_0247	3.209e-138	462.0	COG0477@1|root,COG0477@2|Bacteria,2IBIG@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_1994606_3	1121877.JQKF01000002_gene1746	3.569e-95	334.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4CN74@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRD3_k127_1994606_6	1235457.C404_23985	1.235e-06	51.0	COG3250@1|root,COG3250@2|Bacteria,1R87I@1224|Proteobacteria,2VH83@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Protein of unknown function (DUF2804)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2804
SRD3_k127_1994992_0	882082.SaccyDRAFT_2707	4.247e-50	185.0	COG0132@1|root,COG0132@2|Bacteria,2H6DY@201174|Actinobacteria	201174|Actinobacteria	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_26
SRD3_k127_2009521_3	1192034.CAP_3555	1.578e-24	105.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WQ3M@28221|Deltaproteobacteria,2Z1Q1@29|Myxococcales	28221|Deltaproteobacteria	K	Cold-shock protein	cspD	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRD3_k127_2009521_1	525909.Afer_0306	4.761e-126	426.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4CMTW@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRD3_k127_2009521_0	298654.FraEuI1c_2263	0.0	1147.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4ERSS@85013|Frankiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRD3_k127_2009521_2	1121272.KB903251_gene855	5.492e-45	171.0	2C7TJ@1|root,31RF6@2|Bacteria,2GP9X@201174|Actinobacteria,4D9XX@85008|Micromonosporales	201174|Actinobacteria	G	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	5.2.1.4	ko:K16163	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R03868	RC00867	ko00000,ko00001,ko01000	-	-	-	MDMPI_C,MDMPI_N
SRD3_k127_2030359_1	479433.Caci_3373	1.939e-15	79.0	297DF@1|root,33IUH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2030359_0	351607.Acel_1882	3.988e-136	466.0	COG2202@1|root,COG2203@1|root,COG2208@1|root,COG3852@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3852@2|Bacteria,2GK8P@201174|Actinobacteria,4EU0V@85013|Frankiales	201174|Actinobacteria	T	protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,PAS_9,SpoIIE
SRD3_k127_2034841_3	323259.Mhun_1271	3.947e-22	101.0	COG0437@1|root,arCOG01500@2157|Archaea,2XZP8@28890|Euryarchaeota,2NBK0@224756|Methanomicrobia	224756|Methanomicrobia	C	4Fe-4S dicluster domain	-	-	-	ko:K00196	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	-	R07157,R08034	RC00250,RC02800	ko00000,ko00001	-	-	-	Fer4_11
SRD3_k127_2034841_0	1125863.JAFN01000001_gene2907	1.578e-272	855.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
SRD3_k127_2034841_2	593117.TGAM_0822	4.467e-69	244.0	COG3640@1|root,arCOG00587@2157|Archaea,2XW7J@28890|Euryarchaeota,2437K@183968|Thermococci	183968|Thermococci	D	Anion-transporting ATPase	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
SRD3_k127_2034841_1	1232437.KL662016_gene1214	7.39e-79	287.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,42PSQ@68525|delta/epsilon subdivisions,2WKDY@28221|Deltaproteobacteria,2MK85@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
SRD3_k127_207889_2	235985.BBPN01000020_gene6517	1.337e-36	145.0	COG1611@1|root,COG1611@2|Bacteria,2IN1B@201174|Actinobacteria,2NMFW@228398|Streptacidiphilus	201174|Actinobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRD3_k127_207889_1	1033730.CAHG01000015_gene674	3.102e-38	156.0	COG2802@1|root,COG2802@2|Bacteria,2GNWA@201174|Actinobacteria,4DR7G@85009|Propionibacteriales	201174|Actinobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
SRD3_k127_207889_0	710686.Mycsm_01037	1.044e-80	273.0	COG0300@1|root,COG0300@2|Bacteria,2GMI7@201174|Actinobacteria,2389H@1762|Mycobacteriaceae	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_2080645_5	1502851.FG93_02530	1.055e-24	116.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,2TQM1@28211|Alphaproteobacteria,3JUSP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	idhA	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRD3_k127_2080645_4	96561.Dole_0119	7.809e-26	119.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,DUF3749
SRD3_k127_2080645_7	1448860.BBJO01000002_gene2096	3.005e-06	57.0	COG0346@1|root,arCOG02708@2157|Archaea,2Y08Q@28890|Euryarchaeota,23XQN@183963|Halobacteria	183963|Halobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	lgl	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRD3_k127_2080645_2	1048339.KB913029_gene3828	1.843e-67	239.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4ETG1@85013|Frankiales	201174|Actinobacteria	GK	PFAM ROK family	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRD3_k127_2080645_6	383372.Rcas_4302	1.045e-09	70.0	COG2199@1|root,COG3706@2|Bacteria,2GAEA@200795|Chloroflexi,375RZ@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRD3_k127_2080645_3	479435.Kfla_5438	2.588e-46	175.0	COG2128@1|root,COG2128@2|Bacteria,2I829@201174|Actinobacteria,4DRMY@85009|Propionibacteriales	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRD3_k127_2080645_0	1122247.C731_2740	1.639e-185	593.0	COG3804@1|root,COG3804@2|Bacteria,2I8GH@201174|Actinobacteria,23455@1762|Mycobacteriaceae	201174|Actinobacteria	S	dihydrodipicolinate reductase	dapB_3	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
SRD3_k127_2080645_1	298655.KI912266_gene5438	3.815e-91	306.0	COG1028@1|root,COG1028@2|Bacteria,2GMAG@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD3_k127_2080645_8	1121377.KB906417_gene3855	4.303e-06	59.0	2FA15@1|root,342A8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2115948_1	1313172.YM304_11100	4.765e-104	351.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4CMSA@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Peptidase family M1 domain	-	-	-	ko:K08776	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRD3_k127_2115948_2	1123366.TH3_01680	7.588e-99	336.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,2JPGW@204441|Rhodospirillales	204441|Rhodospirillales	G	COG0524 Sugar kinases, ribokinase family	pfkB	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRD3_k127_2115948_3	1237500.ANBA01000017_gene1803	1.793e-49	188.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRD3_k127_2115948_0	1229780.BN381_20071	3.996e-120	398.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,3UWA3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRD3_k127_2121298_0	106370.Francci3_1050	1.249e-265	867.0	COG1572@1|root,COG1572@2|Bacteria,2I56C@201174|Actinobacteria,4EXBH@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF3367)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3367
SRD3_k127_2121298_1	1242864.D187_005969	4.446e-106	362.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
SRD3_k127_2159483_3	313625.BL107_13000	2.827e-33	131.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1G0PS@1117|Cyanobacteria,1GZKK@1129|Synechococcus	1117|Cyanobacteria	H	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRD3_k127_2159483_1	525909.Afer_0722	2.65e-56	203.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria,4CNRB@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRD3_k127_2159483_0	1229780.BN381_80028	9.071e-112	380.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,3UWAR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRD3_k127_2159483_4	1313172.YM304_19200	7.316e-25	113.0	COG0317@1|root,COG0317@2|Bacteria	2|Bacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	sdaAB	-	2.7.6.5,3.1.7.2,4.3.1.17,4.3.1.19	ko:K01139,ko:K01752,ko:K01754	ko00230,ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00230,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00336,R00429,R00590,R00996	RC00002,RC00078,RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	ACT,HD_4,PALP,RelA_SpoT,SDH_beta
SRD3_k127_2159483_2	1313172.YM304_29090	2.245e-36	151.0	2BJWW@1|root,32E9A@2|Bacteria,2HGG7@201174|Actinobacteria,4CNDN@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2159483_5	479434.Sthe_0027	1.926e-16	90.0	COG2199@1|root,COG3852@1|root,COG2199@2|Bacteria,COG3852@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,HATPase_c,HisKA,MASE1,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRD3_k127_2226138_0	269800.Tfu_2582	1.034e-79	269.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4EHIU@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	tcsR3	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD3_k127_2226138_1	512565.AMIS_4230	4.839e-06	50.0	COG1028@1|root,COG1028@2|Bacteria,2IDD0@201174|Actinobacteria,4DD4W@85008|Micromonosporales	201174|Actinobacteria	IQ	KR domain	fabG1	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD3_k127_2265635_0	1283287.KB822577_gene3217	7.41e-70	257.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DWF4@85009|Propionibacteriales	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,HAMP,PAS,PAS_8
SRD3_k127_2268275_7	1380390.JIAT01000012_gene3001	7.677e-57	211.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRD3_k127_2268275_5	203124.Tery_1481	8.077e-74	269.0	COG1216@1|root,COG1216@2|Bacteria,1GQRA@1117|Cyanobacteria,1HBGK@1150|Oscillatoriales	1117|Cyanobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2268275_10	886293.Sinac_4409	3.868e-18	100.0	COG1216@1|root,COG1216@2|Bacteria,2J1FB@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD3_k127_2268275_1	1122939.ATUD01000006_gene1711	6.774e-169	570.0	COG0438@1|root,COG2227@1|root,COG0438@2|Bacteria,COG2227@2|Bacteria,2GUEW@201174|Actinobacteria,4CPRR@84995|Rubrobacteria	84995|Rubrobacteria	MQ	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Methyltransf_23
SRD3_k127_2268275_4	886293.Sinac_4409	2.584e-76	289.0	COG1216@1|root,COG1216@2|Bacteria,2J1FB@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD3_k127_2268275_3	1380390.JIAT01000012_gene2999	5.461e-127	445.0	COG0438@1|root,COG0463@1|root,COG1216@1|root,COG0438@2|Bacteria,COG0463@2|Bacteria,COG1216@2|Bacteria,2HENX@201174|Actinobacteria,4CRKC@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRD3_k127_2268275_0	1380390.JIAT01000012_gene2998	1.122e-191	634.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CRBA@84995|Rubrobacteria	84995|Rubrobacteria	V	COG COG1132 ABC-type multidrug transport system ATPase and permease components Defense mechanisms	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRD3_k127_2268275_2	489825.LYNGBM3L_21220	1.083e-148	509.0	COG1216@1|root,COG5309@1|root,COG1216@2|Bacteria,COG5309@2|Bacteria,1G2MT@1117|Cyanobacteria,1H8YG@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glycos_transf_2
SRD3_k127_2268275_8	1123322.KB904698_gene4698	1.817e-43	175.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRD3_k127_2268275_6	1206732.BAGD01000053_gene1866	2.598e-64	230.0	COG0204@1|root,COG0204@2|Bacteria,2GNBB@201174|Actinobacteria,4FZHY@85025|Nocardiaceae	201174|Actinobacteria	I	Diacylglycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRD3_k127_2268275_9	1229780.BN381_360018	5.342e-42	158.0	COG1020@1|root,COG1020@2|Bacteria,2I5H8@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the long-chain O-acyltransferase family	-	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRD3_k127_2279470_3	710111.FraQA3DRAFT_2695	3.284e-151	490.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4EUA5@85013|Frankiales	201174|Actinobacteria	EGP	drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_2279470_9	251229.Chro_4000	1.775e-54	203.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,3VK4S@52604|Pleurocapsales	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRD3_k127_2279470_6	1205680.CAKO01000016_gene143	2.299e-87	294.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2U16Z@28211|Alphaproteobacteria,2JRZM@204441|Rhodospirillales	204441|Rhodospirillales	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRD3_k127_2279470_0	981369.JQMJ01000004_gene1085	9.152e-200	637.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,2NKRD@228398|Streptacidiphilus	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRD3_k127_2279470_11	1267533.KB906734_gene3952	3.558e-26	123.0	2DNAS@1|root,32WH6@2|Bacteria,3Y5UC@57723|Acidobacteria,2JKNS@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2279470_2	419947.MRA_0787	2.59e-187	593.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,232YJ@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome p450	cyp126A3	GO:0003674,GO:0003824,GO:0004497,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0046164,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652	-	-	-	-	-	-	-	-	-	-	p450
SRD3_k127_2279470_1	222534.KB893725_gene255	1.413e-189	606.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria,4ESDV@85013|Frankiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_2279470_5	1394178.AWOO02000034_gene8340	1.115e-94	322.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRD3_k127_2279470_8	1173028.ANKO01000044_gene779	1.076e-61	228.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1HAHP@1150|Oscillatoriales	1117|Cyanobacteria	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRD3_k127_2279470_10	1205680.CAKO01000029_gene5135	1.576e-42	168.0	COG2084@1|root,COG2084@2|Bacteria,1PU4S@1224|Proteobacteria,2TT0X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRD3_k127_2279470_4	298655.KI912266_gene3843	1.016e-139	469.0	COG0183@1|root,COG0183@2|Bacteria,2IDT4@201174|Actinobacteria	201174|Actinobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
SRD3_k127_2279470_7	1429046.RR21198_4075	2.11e-73	266.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4FYX8@85025|Nocardiaceae	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRD3_k127_2279470_13	1121382.JQKG01000004_gene4091	1.949e-05	54.0	COG4315@1|root,COG4315@2|Bacteria	2|Bacteria	P	Pfam Secreted repeat of	MA20_31645	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRD3_k127_2279470_12	1283299.AUKG01000001_gene2767	1.483e-15	87.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria,4CSR4@84995|Rubrobacteria	84995|Rubrobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRD3_k127_2299660_0	1229780.BN381_330101	9.764e-103	349.0	COG1199@1|root,COG1199@2|Bacteria,2GKT8@201174|Actinobacteria,3UW6B@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	KL	HELICc2	dinG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
SRD3_k127_2299660_1	1313172.YM304_24100	4.962e-71	246.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4CN3C@84992|Acidimicrobiia	84992|Acidimicrobiia	J	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRD3_k127_2311950_4	1229780.BN381_290134	1.742e-15	80.0	2FH85@1|root,3492H@2|Bacteria,2H8HQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2311950_1	1121877.JQKF01000023_gene2237	4.016e-125	406.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4CMTS@84992|Acidimicrobiia	84992|Acidimicrobiia	F	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRD3_k127_2311950_3	644966.Tmar_1990	7.254e-39	153.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,3WD5U@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRD3_k127_2311950_0	1121877.JQKF01000023_gene2239	1.874e-175	565.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,4CN1A@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRD3_k127_2311950_2	1229780.BN381_50158	1.57e-98	328.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,3UWIW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRD3_k127_2322348_2	497964.CfE428DRAFT_0103	4.698e-30	133.0	COG4956@1|root,COG4956@2|Bacteria,46U4H@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2322348_0	351607.Acel_2020	2.285e-161	527.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4ERWF@85013|Frankiales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRD3_k127_2322348_3	1179773.BN6_15500	1.491e-27	128.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria,4E5KZ@85010|Pseudonocardiales	201174|Actinobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRD3_k127_2322348_1	446462.Amir_1304	1.971e-115	384.0	COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,4DX8X@85010|Pseudonocardiales	201174|Actinobacteria	C	NAD NADP transhydrogenase alpha subunit	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRD3_k127_2423961_3	1123023.JIAI01000003_gene3072	2.579e-34	138.0	COG0346@1|root,COG0346@2|Bacteria,2IQE0@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD3_k127_2423961_4	1283299.AUKG01000001_gene2158	8.643e-12	72.0	2B8TX@1|root,32240@2|Bacteria,2HRST@201174|Actinobacteria,4CTW1@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2423961_2	1227261.HMPREF0043_01385	1.582e-41	160.0	COG0454@1|root,COG0456@2|Bacteria,2IMVD@201174|Actinobacteria,4D5W9@85005|Actinomycetales	201174|Actinobacteria	K	(GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD3_k127_2423961_0	2074.JNYD01000015_gene4563	4.833e-111	371.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4DZFW@85010|Pseudonocardiales	201174|Actinobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRD3_k127_2423961_1	105420.BBPO01000020_gene5614	1.026e-41	168.0	COG3119@1|root,COG3119@2|Bacteria,2IA3D@201174|Actinobacteria,2NI27@228398|Streptacidiphilus	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRD3_k127_2481826_0	1229780.BN381_80226	1.495e-81	279.0	COG2887@1|root,COG2887@2|Bacteria,2GJC5@201174|Actinobacteria,3UWVT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	recB	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
SRD3_k127_2481826_1	1206731.BAGB01000047_gene5366	6.89e-07	60.0	2E5H4@1|root,3308M@2|Bacteria,2IJ95@201174|Actinobacteria,4G9YZ@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	ko:K18481	-	M00670	-	-	ko00000,ko00002,ko02000	3.A.1.27.4,3.A.1.27.5	-	-	TPR_21
SRD3_k127_2496080_1	44454.NF84_08590	5.429e-123	407.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria,2338T@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
SRD3_k127_2496080_7	931277.C448_12276	1.015e-34	153.0	COG1545@1|root,arCOG01285@2157|Archaea,2XXG8@28890|Euryarchaeota,23VS7@183963|Halobacteria	183963|Halobacteria	V	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRD3_k127_2496080_2	1227457.C451_18873	2.124e-104	365.0	COG0183@1|root,arCOG01278@2157|Archaea,2XVM2@28890|Euryarchaeota,23TYT@183963|Halobacteria	183963|Halobacteria	I	COG0183 Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
SRD3_k127_2496080_4	1394178.AWOO02000013_gene7864	7.611e-74	279.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4EHHR@85012|Streptosporangiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRD3_k127_2496080_3	1206725.BAFU01000246_gene2480	8.255e-96	340.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4FW1X@85025|Nocardiaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRD3_k127_2496080_0	298654.FraEuI1c_3304	9.552e-194	613.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EUWU@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRD3_k127_2496080_8	1121272.KB903283_gene5157	2.292e-08	62.0	2EMYX@1|root,33FM2@2|Bacteria,2GZ6D@201174|Actinobacteria,4DKE1@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2496080_6	929712.KI912613_gene4618	9.471e-44	168.0	COG2114@1|root,COG2114@2|Bacteria,2ICJJ@201174|Actinobacteria,4CQDR@84995|Rubrobacteria	84995|Rubrobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRD3_k127_2496080_5	1463841.JOIR01000014_gene1416	4.028e-72	250.0	COG0657@1|root,COG0657@2|Bacteria,2GJYR@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRD3_k127_2518073_3	1240349.ANGC01000017_gene4761	5.8e-38	145.0	COG1752@1|root,COG1752@2|Bacteria,2HJ6N@201174|Actinobacteria,4G5HY@85025|Nocardiaceae	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRD3_k127_2518073_2	266117.Rxyl_1997	8.316e-55	206.0	COG0454@1|root,COG0456@2|Bacteria,2I4BM@201174|Actinobacteria,4CQBU@84995|Rubrobacteria	84995|Rubrobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD3_k127_2518073_1	1394178.AWOO02000013_gene7962	1.462e-66	235.0	COG0789@1|root,COG0789@2|Bacteria,2I8PU@201174|Actinobacteria,4EJGP@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRD3_k127_2518073_0	1394178.AWOO02000061_gene5972	2.577e-81	278.0	COG3396@1|root,COG3396@2|Bacteria,2GMBI@201174|Actinobacteria,4EI43@85012|Streptosporangiales	201174|Actinobacteria	S	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
SRD3_k127_251902_4	1894.JOER01000033_gene4222	9.125e-07	58.0	COG3468@1|root,COG3468@2|Bacteria,2IKH3@201174|Actinobacteria	201174|Actinobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	TIG
SRD3_k127_251902_0	525909.Afer_1918	7.983e-76	259.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4CMZF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sigma-70, region 4	sigR	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD3_k127_251902_2	525909.Afer_1917	6.893e-19	89.0	29XP9@1|root,30JEV@2|Bacteria,2HGER@201174|Actinobacteria,4CNCS@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRD3_k127_251902_1	1229780.BN381_110020	9.112e-72	252.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,3UXC9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Pfam:Zinicin_2	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRD3_k127_2576109_0	1380347.JNII01000006_gene1174	6.282e-148	479.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4ES53@85013|Frankiales	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRD3_k127_2576109_1	1121946.AUAX01000019_gene7777	1.673e-48	183.0	COG3340@1|root,COG3340@2|Bacteria,2ISWE@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRD3_k127_2576109_2	1120936.KB907221_gene2141	1.77e-38	154.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_2580922_1	1313172.YM304_24260	4.172e-62	216.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4CMWI@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRD3_k127_2580922_0	1121877.JQKF01000022_gene2267	0.0	1234.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4CMX0@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRD3_k127_2581331_1	1229780.BN381_410039	4.985e-72	252.0	COG2267@1|root,COG2267@2|Bacteria,2GKPK@201174|Actinobacteria,3UXF2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRD3_k127_2581331_2	1313172.YM304_42510	1.224e-69	242.0	COG0300@1|root,COG0300@2|Bacteria,2IIVW@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_2581331_3	1313172.YM304_42510	0.0007574	51.0	COG0300@1|root,COG0300@2|Bacteria,2IIVW@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_2581331_0	326424.FRAAL1978	2.211e-100	337.0	COG0451@1|root,COG0451@2|Bacteria,2GN90@201174|Actinobacteria,4EX9Z@85013|Frankiales	201174|Actinobacteria	M	Male sterility protein	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
SRD3_k127_2596120_6	1283299.AUKG01000001_gene2445	2.141e-35	152.0	COG2199@1|root,COG2203@1|root,COG3290@1|root,COG2203@2|Bacteria,COG3290@2|Bacteria,COG3706@2|Bacteria,2IB0W@201174|Actinobacteria,4CSWI@84995|Rubrobacteria	84995|Rubrobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
SRD3_k127_2596120_7	290397.Adeh_1440	4.051e-33	138.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42UV6@68525|delta/epsilon subdivisions,2WP1R@28221|Deltaproteobacteria,2YVX1@29|Myxococcales	28221|Deltaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRD3_k127_2596120_1	1246995.AFR_25430	2.6e-182	599.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4D8I6@85008|Micromonosporales	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRD3_k127_2596120_3	1051632.TPY_1050	2.179e-102	359.0	COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,25E7N@186801|Clostridia	186801|Clostridia	G	6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRD3_k127_2596120_4	330214.NIDE0356	4.681e-92	319.0	COG0166@1|root,COG0166@2|Bacteria	2|Bacteria	G	Belongs to the GPI family	tal	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
SRD3_k127_2596120_2	1120949.KB903294_gene3987	2.708e-128	431.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4D9UT@85008|Micromonosporales	201174|Actinobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRD3_k127_2596120_0	1229780.BN381_410021	9.358e-232	743.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,3UW9I@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Transketolase, pyrimidine binding domain	tkt	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRD3_k127_2596120_5	575540.Isop_1496	1.989e-47	175.0	COG4398@1|root,COG4398@2|Bacteria,2IXYT@203682|Planctomycetes	203682|Planctomycetes	S	PFAM FIST C domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRD3_k127_2601209_3	42565.FP66_00960	8.892e-21	102.0	COG2199@1|root,COG3706@2|Bacteria,1RBKK@1224|Proteobacteria,1S2QB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRD3_k127_2601209_0	1123024.AUII01000004_gene1559	1.596e-56	217.0	COG1024@1|root,COG1024@2|Bacteria,2IGUN@201174|Actinobacteria,4E9QD@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD3_k127_2601209_1	318167.Sfri_2045	1.315e-54	200.0	COG1024@1|root,COG1024@2|Bacteria,1RAAV@1224|Proteobacteria,1RRTJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD3_k127_2601209_4	66377.JOBH01000006_gene231	5.013e-19	95.0	COG3173@1|root,COG3173@2|Bacteria,2HU7E@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRD3_k127_2601209_2	1122611.KB903939_gene435	2.217e-40	150.0	COG3173@1|root,COG3173@2|Bacteria,2HU7E@201174|Actinobacteria,4EHHI@85012|Streptosporangiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRD3_k127_2604785_0	880070.Cycma_2967	3.098e-50	184.0	COG0251@1|root,COG0251@2|Bacteria,4NPF9@976|Bacteroidetes,47QAB@768503|Cytophagia	976|Bacteroidetes	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRD3_k127_2604785_2	1192034.CAP_5833	9.013e-20	91.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,438NC@68525|delta/epsilon subdivisions,2X3WD@28221|Deltaproteobacteria,2YXBV@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome P450	-	-	1.14.13.151,1.14.15.14	ko:K05525,ko:K20497	ko00902,ko01110,map00902,map01110	-	R04366,R09922,R09923,R09924,R09925	RC01137,RC02561,RC02626	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRD3_k127_2604785_1	1463854.JOHT01000014_gene5111	3.087e-31	125.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	cyp125	GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0036199,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044238,GO:0044281,GO:0044282,GO:0044403,GO:0044419,GO:0046164,GO:0046906,GO:0048037,GO:0051704,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901615,GO:1901616,GO:1902652	1.14.13.141	ko:K15981	ko00984,ko01120,map00984,map01120	-	R09859,R11357	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRD3_k127_2612594_0	290397.Adeh_2440	1.312e-95	327.0	COG0151@1|root,COG0151@2|Bacteria,1NA76@1224|Proteobacteria,43CA7@68525|delta/epsilon subdivisions,2X7KS@28221|Deltaproteobacteria,2Z204@29|Myxococcales	28221|Deltaproteobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
SRD3_k127_2612594_1	1121877.JQKF01000024_gene2390	5.569e-54	199.0	COG0694@1|root,COG0694@2|Bacteria,2HGAJ@201174|Actinobacteria,4CN9Q@84992|Acidimicrobiia	84992|Acidimicrobiia	O	NifU-like domain	-	-	-	ko:K07400	-	-	-	-	ko00000	-	-	-	NifU
SRD3_k127_2612594_2	1157638.KB892165_gene3607	2.71e-33	144.0	COG1989@1|root,COG1989@2|Bacteria,2IDFY@201174|Actinobacteria	201174|Actinobacteria	NOU	Bacterial Peptidase A24 N-terminal domain	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRD3_k127_2614663_3	1313172.YM304_19640	4.52e-54	196.0	COG0778@1|root,COG0778@2|Bacteria,2GW57@201174|Actinobacteria,4CN7W@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRD3_k127_2614663_1	525909.Afer_0728	1.256e-174	569.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CMRS@84992|Acidimicrobiia	84992|Acidimicrobiia	HP	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,ThiF
SRD3_k127_2614663_0	1313172.YM304_28970	1.656e-246	770.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4CMX5@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRD3_k127_2614663_2	1463855.JOHV01000010_gene5531	6.811e-119	395.0	COG1473@1|root,COG1473@2|Bacteria,2GNEG@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase, M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRD3_k127_2614663_4	525909.Afer_0730	1.408e-08	56.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4CMS3@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRD3_k127_2626856_1	47839.CCAU010000019_gene3438	2.338e-101	335.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria,2338T@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
SRD3_k127_2626856_2	1448389.BAVQ01000036_gene973	9.366e-27	122.0	COG1545@1|root,COG1545@2|Bacteria,2II25@201174|Actinobacteria	201174|Actinobacteria	EGP	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRD3_k127_2626856_0	29306.JOBE01000003_gene4207	7.218e-102	339.0	COG2141@1|root,COG2141@2|Bacteria,2GJI7@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_2636194_0	1229780.BN381_50144	6.938e-293	913.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,3UW8D@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRD3_k127_2636194_2	1229780.BN381_50141	6.303e-135	450.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,3UWBX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383	CPSase_sm_chain,GATase
SRD3_k127_2636194_1	1229780.BN381_50140	1.076e-143	471.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,3UWBY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRD3_k127_2636194_3	1313172.YM304_20430	1.206e-97	338.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4CN9W@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRD3_k127_2636194_5	1229780.BN381_50138	9.288e-66	232.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,3UWP5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRD3_k127_2636194_7	1313172.YM304_20390	1.108e-29	123.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4CNC8@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRD3_k127_2636194_4	1121877.JQKF01000024_gene2404	3.651e-80	280.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CMZZ@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRD3_k127_2636194_6	1077144.AGFF01000023_gene1328	2.444e-55	198.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase M24B family	pepQ	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRD3_k127_2640092_1	1299327.I546_3628	2.027e-116	385.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,237H5@1762|Mycobacteriaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_2640092_0	1041522.MCOL_V209005	3.987e-141	454.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRD3_k127_2640404_8	1429046.RR21198_0377	4.447e-17	82.0	COG3616@1|root,COG3616@2|Bacteria,2GK0N@201174|Actinobacteria,4FVTZ@85025|Nocardiaceae	201174|Actinobacteria	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRD3_k127_2640404_2	1242864.D187_004098	3.432e-89	309.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,438PG@68525|delta/epsilon subdivisions,2X3X6@28221|Deltaproteobacteria,2YXF3@29|Myxococcales	28221|Deltaproteobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRD3_k127_2640404_7	1211815.CBYP010000061_gene35	1.173e-30	134.0	COG1309@1|root,COG1309@2|Bacteria,2HTXS@201174|Actinobacteria,4EVE1@85013|Frankiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD3_k127_2640404_0	100226.SCO5810	1.89e-129	439.0	COG0477@1|root,COG0477@2|Bacteria,2IBIG@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_2640404_10	1121877.JQKF01000025_gene811	1.376e-08	67.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2640404_6	570268.ANBB01000032_gene1465	1.239e-64	237.0	COG0860@1|root,COG0860@2|Bacteria,2GPA9@201174|Actinobacteria,4EM6I@85012|Streptosporangiales	201174|Actinobacteria	M	Ami_3	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
SRD3_k127_2640404_9	309807.SRU_1202	2.251e-11	72.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1FJ5I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Bacterial regulatory protein, Fis family	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRD3_k127_2640404_4	1333998.M2A_2111	1.001e-76	269.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2TUVX@28211|Alphaproteobacteria,4BT8D@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
SRD3_k127_2640404_3	1120949.KB903317_gene1769	3.314e-88	300.0	COG0596@1|root,COG0596@2|Bacteria,2GJDM@201174|Actinobacteria,4DH3T@85008|Micromonosporales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRD3_k127_2640404_1	1944.JOAZ01000023_gene2555	1.445e-92	322.0	COG1131@1|root,COG1131@2|Bacteria,2IE14@201174|Actinobacteria	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRD3_k127_2640404_5	1944.JOAZ01000023_gene2556	3.337e-76	274.0	COG0842@1|root,COG0842@2|Bacteria,2I9MM@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
SRD3_k127_264945_1	1229780.BN381_80043	3.198e-152	486.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,3UWCK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRD3_k127_264945_0	1134445.AJJM01000007_gene3105	7.176e-213	679.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria	201174|Actinobacteria	S	Modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRD3_k127_264945_2	1155714.KB891988_gene2201	1.89e-138	477.0	COG0312@1|root,COG0312@2|Bacteria,2GZPS@201174|Actinobacteria	201174|Actinobacteria	S	modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
SRD3_k127_264945_3	351607.Acel_0114	3.236e-41	153.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4ERX6@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRD3_k127_2693021_2	298653.Franean1_3648	8.96e-87	289.0	COG3576@1|root,COG3576@2|Bacteria,2I3NE@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRD3_k127_2693021_5	1220534.B655_2000	1.307e-22	104.0	COG5646@1|root,arCOG09457@2157|Archaea,2Y1ED@28890|Euryarchaeota	28890|Euryarchaeota	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRD3_k127_2693021_6	1215092.PA6_005_00340	2.683e-08	62.0	COG1359@1|root,COG1359@2|Bacteria,1NGPW@1224|Proteobacteria,1SB35@1236|Gammaproteobacteria,1YGTB@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRD3_k127_2693021_3	929712.KI912613_gene4990	8.475e-37	144.0	COG4308@1|root,COG4308@2|Bacteria,2IN4A@201174|Actinobacteria	201174|Actinobacteria	Q	limonene-1,2-epoxide hydrolase	ephG	GO:0003674,GO:0003824,GO:0004301,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016801,GO:0016803,GO:0018904,GO:0033963,GO:0044237,GO:0044281,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0097176,GO:1901360	3.3.2.8	ko:K10533	ko00903,map00903	-	R05784,R09387	RC01473,RC02519	ko00000,ko00001,ko01000	-	-	-	LEH
SRD3_k127_2693021_1	2002.JOEQ01000026_gene370	8.227e-94	319.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria,4EHHD@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_2693021_4	1128421.JAGA01000002_gene1242	4.147e-35	156.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD3_k127_2693021_0	35754.JNYJ01000011_gene731	8.601e-195	646.0	COG2898@1|root,COG2898@2|Bacteria,2I2ZR@201174|Actinobacteria,4DBVQ@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3,6.1.1.6	ko:K04567,ko:K14205	ko00970,ko01503,ko02020,ko05150,map00970,map01503,map02020,map05150	M00359,M00360,M00726	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko01504,ko03016	2.A.1.3.37	-	-	DUF2156,tRNA-synt_2_TM
SRD3_k127_2696094_1	1333856.L686_11915	2.052e-22	111.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1Z05X@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD3_k127_2696094_0	68219.JNXI01000001_gene5863	1.333e-93	316.0	COG1127@1|root,COG1127@2|Bacteria,2GJ1T@201174|Actinobacteria	201174|Actinobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRD3_k127_2696094_2	1123258.AQXZ01000016_gene2642	1.04e-09	65.0	COG0671@1|root,COG1597@1|root,COG0671@2|Bacteria,COG1597@2|Bacteria,2GM2U@201174|Actinobacteria,4FWPQ@85025|Nocardiaceae	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	bmrU	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DAGK_cat,PAP2
SRD3_k127_2706633_0	562970.Btus_1437	6.433e-35	146.0	COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,2787H@186823|Alicyclobacillaceae	91061|Bacilli	T	Belongs to the peptidase S16 family	-	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
SRD3_k127_2706633_1	1313172.YM304_05090	6.077e-16	90.0	COG3599@1|root,COG3599@2|Bacteria	2|Bacteria	D	regulation of cell shape	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
SRD3_k127_2717673_2	1313172.YM304_08910	1.293e-57	218.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CMZ5@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRD3_k127_2717673_4	1313172.YM304_08850	1.15e-28	130.0	COG0736@1|root,COG0736@2|Bacteria,2HGFC@201174|Actinobacteria,4CND0@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRD3_k127_2717673_0	1236902.ANAS01000019_gene4292	6.006e-191	616.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4EGKR@85012|Streptosporangiales	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
SRD3_k127_2717673_1	43354.JOIJ01000010_gene2515	1.037e-131	434.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4DXC8@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	GO:0008150,GO:0040007	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRD3_k127_2717673_3	1229780.BN381_130024	4.159e-46	172.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,3UWN9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRD3_k127_2717673_5	1227261.HMPREF0043_00879	4.695e-10	60.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4D37G@85005|Actinomycetales	201174|Actinobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRD3_k127_273206_1	390989.JOEG01000003_gene4485	2.357e-53	197.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4D8I2@85008|Micromonosporales	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRD3_k127_273206_0	1380356.JNIK01000005_gene968	6.246e-149	492.0	COG0075@1|root,COG0075@2|Bacteria,2GM5F@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	-	-	2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588,R10908	RC00006,RC00008,RC00018,RC03305	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRD3_k127_2733361_0	351607.Acel_1394	1.552e-183	580.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4ESAU@85013|Frankiales	201174|Actinobacteria	C	Aconitate hydratase 1	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRD3_k127_2733361_2	290397.Adeh_0418	1.75e-37	159.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1QYFP@1224|Proteobacteria,43CBV@68525|delta/epsilon subdivisions,2X7MN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA
SRD3_k127_2733361_3	293227.XP_008719675.1	2.836e-09	66.0	2EQNK@1|root,2STMR@2759|Eukaryota,3A9GP@33154|Opisthokonta,3P6PU@4751|Fungi,3QZ4P@4890|Ascomycota,20NID@147545|Eurotiomycetes	4751|Fungi	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
SRD3_k127_2733361_1	675635.Psed_4235	5.298e-64	235.0	COG0515@1|root,COG0515@2|Bacteria,2IAZC@201174|Actinobacteria,4DXAZ@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRD3_k127_2766571_0	47839.CCAU010000004_gene1016	6.931e-148	474.0	COG1063@1|root,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria,23300@1762|Mycobacteriaceae	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_2766571_1	35754.JNYJ01000056_gene9880	6.223e-91	316.0	COG5001@1|root,COG5001@2|Bacteria,2IAJD@201174|Actinobacteria,4DIBZ@85008|Micromonosporales	201174|Actinobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_4
SRD3_k127_2766571_3	222534.KB893750_gene4397	3.428e-17	94.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,4ETKR@85013|Frankiales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	rskA	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRD3_k127_2766571_2	1121877.JQKF01000003_gene1493	4.736e-48	185.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4CN9P@84992|Acidimicrobiia	84992|Acidimicrobiia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD3_k127_2766571_4	929712.KI912613_gene1834	3.356e-07	57.0	2FF2Y@1|root,34717@2|Bacteria,2GTPB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2780099_1	1313172.YM304_19140	1.11e-44	170.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4CN28@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferases group 1	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRD3_k127_2780099_4	1032480.MLP_41720	2.799e-09	60.0	2EGHN@1|root,33A9R@2|Bacteria,2HZFR@201174|Actinobacteria,4DSMW@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2780099_2	1229780.BN381_140045	7.006e-24	103.0	2ES7R@1|root,33JSG@2|Bacteria,2I1DU@201174|Actinobacteria,3UXPZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2780099_0	1229780.BN381_140046	1.619e-60	217.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,2GMC0@201174|Actinobacteria,3UWMB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	GIY-YIG type nucleases (URI domain)	dnaQ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
SRD3_k127_2780099_3	1380393.JHVP01000003_gene1058	1.84e-21	96.0	COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria,4ETA3@85013|Frankiales	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRD3_k127_2780099_5	497964.CfE428DRAFT_0631	1.744e-05	53.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRD3_k127_2785599_1	1370125.AUWT01000055_gene985	1.392e-57	223.0	COG1028@1|root,COG1028@2|Bacteria,2HP88@201174|Actinobacteria,23415@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Dehydrogenase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD3_k127_2785599_3	1370120.AUWR01000081_gene915	1.374e-29	122.0	COG0599@1|root,COG0599@2|Bacteria,2IFMB@201174|Actinobacteria,238R6@1762|Mycobacteriaceae	201174|Actinobacteria	S	decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRD3_k127_2785599_2	58123.JOFJ01000003_gene2075	9.948e-50	184.0	COG1309@1|root,COG1309@2|Bacteria,2I9ZN@201174|Actinobacteria,4EP25@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD3_k127_2785599_0	1394178.AWOO02000025_gene4986	4.266e-164	543.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4EHPD@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	cyp123A3	GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652	-	-	-	-	-	-	-	-	-	-	p450
SRD3_k127_283302_1	1313172.YM304_19170	1.77e-74	259.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4CNH1@84992|Acidimicrobiia	201174|Actinobacteria	G	ROK family	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRD3_k127_283302_0	471853.Bcav_0959	3.516e-189	597.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	-	-	2.6.1.1,2.6.1.17,2.6.1.83	ko:K00812,ko:K08969,ko:K10206,ko:K14261,ko:K14267	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00034,M00527	R00355,R00694,R00734,R00896,R02433,R02619,R04475,R05052,R07396,R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRD3_k127_283302_3	1229780.BN381_140034	6.866e-41	160.0	COG1309@1|root,COG1309@2|Bacteria,2GXGA@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD3_k127_283302_2	222534.KB893711_gene5015	8.691e-74	256.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4ERMB@85013|Frankiales	201174|Actinobacteria	I	PFAM Phospholipid glycerol acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRD3_k127_2845700_0	1298880.AUEV01000009_gene3121	4.419e-40	157.0	COG0454@1|root,COG0456@2|Bacteria,2GMPX@201174|Actinobacteria	201174|Actinobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD3_k127_2845700_2	1463858.JOHR01000001_gene6536	8.462e-26	121.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2845700_1	1299327.I546_6544	3.007e-38	149.0	2C72U@1|root,32W8F@2|Bacteria,2GTSA@201174|Actinobacteria,2396T@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2845700_3	258052.JNYV01000008_gene3543	1.438e-06	50.0	2F5RB@1|root,33YA7@2|Bacteria,2GMGC@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2,SnoaL_4
SRD3_k127_2852651_4	1385519.N801_15030	6.712e-45	178.0	COG0572@1|root,COG0572@2|Bacteria,2I5X2@201174|Actinobacteria,4FJI0@85021|Intrasporangiaceae	201174|Actinobacteria	F	uridine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2852651_3	1313172.YM304_37310	3.275e-52	200.0	COG3871@1|root,COG3871@2|Bacteria,2GWY2@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRD3_k127_2852651_1	555793.WSK_3610	3.614e-89	316.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TTRD@28211|Alphaproteobacteria,2K4UJ@204457|Sphingomonadales	204457|Sphingomonadales	C	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_2852651_0	557599.MKAN_19810	4.763e-145	467.0	COG0111@1|root,COG0111@2|Bacteria,2GIZV@201174|Actinobacteria,236W4@1762|Mycobacteriaceae	201174|Actinobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA2	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRD3_k127_2852651_2	710686.Mycsm_01044	2.924e-77	280.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,2363K@1762|Mycobacteriaceae	201174|Actinobacteria	G	Belongs to the FGGY kinase family	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRD3_k127_2854477_0	1380390.JIAT01000013_gene145	5.353e-32	140.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,2GJRI@201174|Actinobacteria	201174|Actinobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
SRD3_k127_2854591_3	1265502.KB905938_gene2446	1.803e-34	133.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,4AA0X@80864|Comamonadaceae	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRD3_k127_2854591_2	1121877.JQKF01000021_gene2218	9.025e-40	155.0	COG0234@1|root,COG0234@2|Bacteria,2IHRC@201174|Actinobacteria,4CN9G@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRD3_k127_2854591_1	197221.22293954	5.058e-43	162.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1G02G@1117|Cyanobacteria	1117|Cyanobacteria	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
SRD3_k127_2854591_0	1229780.BN381_80375	5.803e-165	540.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,3UW9N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EH	Anthranilate synthase component 1	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRD3_k127_2854591_4	1229780.BN381_80382	2.539e-18	95.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,3UX0E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRD3_k127_2891886_1	1156844.KB891831_gene4500	1.197e-63	239.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycoside hydrolase, family 38	-	-	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRD3_k127_2891886_2	208439.AJAP_07590	6.323e-51	205.0	COG2114@1|root,COG2114@2|Bacteria,2GN02@201174|Actinobacteria,4E1TB@85010|Pseudonocardiales	201174|Actinobacteria	T	Adenylate cyclase regulatory domain	cya	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Ad_Cy_reg,Guanylate_cyc
SRD3_k127_2891886_3	383372.Rcas_3980	6.352e-15	89.0	COG1920@1|root,COG1920@2|Bacteria,2G76R@200795|Chloroflexi,377X9@32061|Chloroflexia	32061|Chloroflexia	H	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
SRD3_k127_2891886_0	1313172.YM304_14930	2.444e-82	287.0	COG2120@1|root,COG2120@2|Bacteria,2IR6Y@201174|Actinobacteria,4CN50@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRD3_k127_2940514_2	1313172.YM304_23320	4.452e-63	233.0	COG0539@1|root,COG0539@2|Bacteria,2I7V9@201174|Actinobacteria	201174|Actinobacteria	J	Zc3h12a-like Ribonuclease NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	HC2,RNase_Zc3h12a
SRD3_k127_2940514_3	1313172.YM304_21280	3.086e-56	199.0	COG0764@1|root,COG0764@2|Bacteria,2GQWT@201174|Actinobacteria,4CN5K@84992|Acidimicrobiia	84992|Acidimicrobiia	I	FabA-like domain	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRD3_k127_2940514_1	1313172.YM304_23330	5.078e-93	312.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,4CN0I@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Endonuclease/Exonuclease/phosphatase family	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRD3_k127_2940514_0	1229780.BN381_10320	1.651e-103	363.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,3UW87@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	UvrD-like helicase C-terminal domain	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
SRD3_k127_2940514_4	408672.NBCG_02084	2.86e-35	141.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	acoC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Biotin_lipoyl,E3_binding
SRD3_k127_2946708_3	1229780.BN381_130143	9.743e-10	61.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_2946708_0	1121877.JQKF01000016_gene120	2.158e-253	825.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4CMW1@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRD3_k127_2946708_1	1313172.YM304_05090	1.208e-43	180.0	COG3599@1|root,COG3599@2|Bacteria	2|Bacteria	D	regulation of cell shape	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
SRD3_k127_2946708_2	1288079.AUKN01000001_gene4426	1.58e-37	156.0	COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the peptidase S16 family	lon	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
SRD3_k127_2946708_4	1313172.YM304_05060	4.548e-07	59.0	COG1413@1|root,COG1413@2|Bacteria,2HA0J@201174|Actinobacteria,4CNCY@84992|Acidimicrobiia	84992|Acidimicrobiia	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRD3_k127_2949881_0	1132441.KI519455_gene3657	1.708e-78	269.0	COG3616@1|root,COG3616@2|Bacteria,2GK0N@201174|Actinobacteria	201174|Actinobacteria	E	Alanine racemase	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRD3_k127_2949881_1	880073.Calab_0133	3.629e-36	158.0	COG0860@1|root,COG1361@1|root,COG3858@1|root,COG0860@2|Bacteria,COG1361@2|Bacteria,COG3858@2|Bacteria,2NQII@2323|unclassified Bacteria	2|Bacteria	M	Glyco_18	-	-	3.4.17.14,3.5.1.28	ko:K01448,ko:K07260,ko:K20276	ko00550,ko01100,ko01502,ko01503,ko02020,ko02024,map00550,map01100,map01502,map01503,map02020,map02024	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036	-	-	-	Amidase_3,CHAP,CW_binding_2,Cu_amine_oxidN1,GBS_Bsp-like,Glyco_hydro_18,Glyco_hydro_25,Peptidase_C39_2,SH3_5,VanY,YSIRK_signal
SRD3_k127_2953938_1	1283299.AUKG01000001_gene2445	7.361e-42	169.0	COG2199@1|root,COG2203@1|root,COG3290@1|root,COG2203@2|Bacteria,COG3290@2|Bacteria,COG3706@2|Bacteria,2IB0W@201174|Actinobacteria,4CSWI@84995|Rubrobacteria	84995|Rubrobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
SRD3_k127_2953938_0	1123024.AUII01000021_gene79	1.055e-71	249.0	COG1060@1|root,COG1060@2|Bacteria,2GK83@201174|Actinobacteria,4DX6M@85010|Pseudonocardiales	201174|Actinobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRD3_k127_2966326_1	525909.Afer_0597	2.225e-13	72.0	COG2267@1|root,COG2267@2|Bacteria,2HF8H@201174|Actinobacteria,4CNE1@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRD3_k127_2966326_0	525909.Afer_0598	9.685e-100	340.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4CN8B@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Mur ligase family, glutamate ligase domain	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRD3_k127_2978396_2	67257.JODR01000006_gene2605	6.036e-33	130.0	COG4122@1|root,COG4122@2|Bacteria,2GP7A@201174|Actinobacteria	201174|Actinobacteria	L	o-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
SRD3_k127_2978396_0	525909.Afer_0351	4.663e-107	360.0	COG1387@1|root,COG1387@2|Bacteria,2IR14@201174|Actinobacteria,4CNF5@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Histidinol phosphate phosphatase, HisJ	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRD3_k127_2978396_1	1313172.YM304_09850	6.069e-101	356.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4CMRV@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Histidine kinase	-	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2
SRD3_k127_3042491_1	1173021.ALWA01000013_gene3002	4.751e-123	399.0	COG0235@1|root,COG0235@2|Bacteria,1G10W@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SRD3_k127_3042491_3	1120936.KB907213_gene4942	1.825e-08	62.0	COG3620@1|root,COG3620@2|Bacteria,2HH2D@201174|Actinobacteria,4EQ3T@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRD3_k127_3042491_2	350058.Mvan_0907	1.994e-56	225.0	COG2159@1|root,COG2159@2|Bacteria,2H2CJ@201174|Actinobacteria	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRD3_k127_3042491_0	1121877.JQKF01000101_gene2377	1.342e-191	610.0	COG0477@1|root,COG2814@2|Bacteria,2I2ZF@201174|Actinobacteria,4CNM3@84992|Acidimicrobiia	84992|Acidimicrobiia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_3053730_0	263358.VAB18032_27931	8.646e-96	330.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4DCDB@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRD3_k127_3053730_1	1313172.YM304_29420	7.04e-26	114.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRD3_k127_3069839_0	1134445.AJJM01000076_gene631	1.77e-89	309.0	COG0596@1|root,COG0596@2|Bacteria,2GJYS@201174|Actinobacteria	201174|Actinobacteria	NU	Alpha beta hydrolase	slpD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRD3_k127_3069839_1	357808.RoseRS_2445	8.88e-46	169.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi,37741@32061|Chloroflexia	32061|Chloroflexia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRD3_k127_3069839_2	68194.JNXR01000006_gene3657	1.176e-26	114.0	COG0239@1|root,COG0239@2|Bacteria,2IKWG@201174|Actinobacteria	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB1	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRD3_k127_3069839_4	66429.JOFL01000009_gene1247	2.051e-13	80.0	COG1993@1|root,COG1993@2|Bacteria,2IM7J@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
SRD3_k127_3069839_3	1370120.AUWR01000023_gene3160	1.041e-23	107.0	COG0239@1|root,COG0239@2|Bacteria,2IKM1@201174|Actinobacteria	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRD3_k127_3073929_3	237609.PSAKL28_47750	1.044e-57	213.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,1S4C3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRD3_k127_3073929_2	37919.EP51_21055	2.084e-68	235.0	COG3832@1|root,COG3832@2|Bacteria,2IHQ1@201174|Actinobacteria,4G1C6@85025|Nocardiaceae	201174|Actinobacteria	S	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRD3_k127_3073929_4	43759.JNWK01000051_gene8098	6.013e-40	154.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria	201174|Actinobacteria	O	Peptidyl-prolyl cis-trans isomerase	fkbP	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRD3_k127_3073929_0	1298864.AUEQ01000001_gene4328	2.511e-107	366.0	COG1234@1|root,COG1234@2|Bacteria,2GJT2@201174|Actinobacteria,23406@1762|Mycobacteriaceae	201174|Actinobacteria	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
SRD3_k127_3073929_1	1380347.JNII01000005_gene3129	1.26e-106	352.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria,4ESAN@85013|Frankiales	201174|Actinobacteria	C	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRD3_k127_3074132_2	468556.AQYG01000050_gene3138	2.165e-08	67.0	COG2385@1|root,COG5479@1|root,COG2385@2|Bacteria,COG5479@2|Bacteria,2ID9T@201174|Actinobacteria,4GBK5@85026|Gordoniaceae	201174|Actinobacteria	DM	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	LGFP,SpoIID
SRD3_k127_3074132_0	644282.Deba_0452	3.751e-53	201.0	COG0438@1|root,COG0438@2|Bacteria,1RM3H@1224|Proteobacteria,42WAY@68525|delta/epsilon subdivisions,2WRXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRD3_k127_3074132_1	760117.JN27_03335	9.376e-42	176.0	COG0438@1|root,COG0438@2|Bacteria,1N5HW@1224|Proteobacteria,2VHEA@28216|Betaproteobacteria,478EV@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRD3_k127_3082657_0	105425.BBPL01000041_gene3497	3.081e-87	295.0	COG1121@1|root,COG1121@2|Bacteria,2GP3A@201174|Actinobacteria,2NEJW@228398|Streptacidiphilus	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02074	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
SRD3_k127_3082657_1	1408418.JNJH01000042_gene699	2.239e-75	262.0	COG1108@1|root,COG1108@2|Bacteria,1PWU3@1224|Proteobacteria,2TVJQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
SRD3_k127_3082657_2	105425.BBPL01000041_gene3495	8.493e-50	201.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,2NGIA@228398|Streptacidiphilus	201174|Actinobacteria	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
SRD3_k127_3131488_5	406817.XNC1_4141	1.149e-09	68.0	28M8C@1|root,2ZAMI@2|Bacteria,1R981@1224|Proteobacteria,1SMPK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_3131488_3	471852.Tcur_3381	6.425e-21	108.0	COG2154@1|root,COG2154@2|Bacteria,2IKXR@201174|Actinobacteria	201174|Actinobacteria	H	dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRD3_k127_3131488_0	251229.Chro_1612	7.394e-218	684.0	COG0114@1|root,COG0114@2|Bacteria,1G0AD@1117|Cyanobacteria	1117|Cyanobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRD3_k127_3131488_4	469371.Tbis_2520	7.435e-21	100.0	2DDBJ@1|root,2ZHEX@2|Bacteria,2GXRW@201174|Actinobacteria,4E7RA@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_3131488_1	1313172.YM304_22440	6.692e-140	453.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,4CMQC@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Alanine dehydrogenase/PNT, N-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRD3_k127_3131488_2	1283299.AUKG01000003_gene352	5.362e-25	115.0	COG3688@1|root,COG3688@2|Bacteria,2I7WE@201174|Actinobacteria,4CQT6@84995|Rubrobacteria	84995|Rubrobacteria	S	YacP-like NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN_YacP
SRD3_k127_3131488_6	391589.RGAI101_3145	9.212e-05	50.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2TRQE@28211|Alphaproteobacteria,2P1RR@2433|Roseobacter	28211|Alphaproteobacteria	L	Rossmann fold nucleotide-binding protein involved in DNA uptake	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRD3_k127_3143711_2	37919.EP51_11605	6.376e-28	115.0	COG2030@1|root,COG2030@2|Bacteria,2IHT0@201174|Actinobacteria,4G0Q2@85025|Nocardiaceae	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRD3_k127_3143711_0	1944.JOAZ01000003_gene5320	4.716e-186	593.0	COG0183@1|root,COG0183@2|Bacteria,2GKFR@201174|Actinobacteria,418GT@629295|Streptomyces griseus group	201174|Actinobacteria	I	lipid-transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N
SRD3_k127_3143711_3	998674.ATTE01000001_gene2209	1.036e-11	77.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,45ZZX@72273|Thiotrichales	1224|Proteobacteria	T	response regulator receiver	dctD	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRD3_k127_3143711_1	1079986.JH164878_gene2102	1.855e-178	575.0	COG0318@1|root,COG0318@2|Bacteria,2GKZ6@201174|Actinobacteria	201174|Actinobacteria	IQ	synthetase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_314573_12	1114959.SZMC14600_04887	1.787e-18	87.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria,4E086@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase carnithine racemase	echA21	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD3_k127_314573_9	1330700.JQNC01000003_gene2034	3.569e-56	214.0	COG0719@1|root,COG0719@2|Bacteria,1WJ1E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	TIGRFAM FeS assembly protein SufD	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRD3_k127_314573_11	1463858.JOHR01000016_gene5418	9.536e-26	121.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	hcaC	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRD3_k127_314573_7	1123267.JONN01000001_gene2067	2.948e-65	235.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2TS8T@28211|Alphaproteobacteria,2K0E3@204457|Sphingomonadales	204457|Sphingomonadales	O	ABC-type transport system involved in Fe-S cluster assembly, ATPase component	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRD3_k127_314573_10	1169161.KB897735_gene5104	8.514e-53	199.0	COG1216@1|root,COG1216@2|Bacteria,2IIII@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_314573_6	1156844.KB891842_gene7290	6.249e-70	240.0	COG0346@1|root,COG0346@2|Bacteria,2IFKS@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	gloA	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase,Glyoxalase_4
SRD3_k127_314573_3	1313172.YM304_34420	2.22e-101	339.0	COG2267@1|root,COG2267@2|Bacteria,2HF8H@201174|Actinobacteria,4CNE1@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRD3_k127_314573_8	1229780.BN381_210086	2.264e-59	220.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,3UWVS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NifU-like N terminal domain	sufU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRD3_k127_314573_2	1229780.BN381_210087	1.24e-147	508.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,3UWF9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Aminotransferase class-V	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRD3_k127_314573_4	525909.Afer_0566	1.075e-99	330.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4CMZ6@84992|Acidimicrobiia	84992|Acidimicrobiia	O	FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRD3_k127_314573_0	351607.Acel_0139	6.103e-246	778.0	COG3408@1|root,COG3408@2|Bacteria,2GIUI@201174|Actinobacteria,4EUUE@85013|Frankiales	201174|Actinobacteria	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRD3_k127_314573_1	246197.MXAN_2879	5.98e-192	614.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,42Q1B@68525|delta/epsilon subdivisions,2WKJH@28221|Deltaproteobacteria,2Z0QK@29|Myxococcales	28221|Deltaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRD3_k127_314573_5	292459.STH1274	8.076e-80	295.0	COG0076@1|root,COG0076@2|Bacteria,1TPVX@1239|Firmicutes,2493I@186801|Clostridia	186801|Clostridia	E	Belongs to the group II decarboxylase family	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRD3_k127_3180946_1	1121877.JQKF01000037_gene1816	1.321e-118	392.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4CN7S@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRD3_k127_3180946_7	526225.Gobs_4362	3.47e-18	99.0	COG3428@1|root,COG3428@2|Bacteria,2GK6Y@201174|Actinobacteria,4ETHA@85013|Frankiales	201174|Actinobacteria	S	PFAM membrane-flanked domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRD3_k127_3180946_8	1121877.JQKF01000024_gene2394	4.596e-08	63.0	COG4969@1|root,COG4969@2|Bacteria,2I7DS@201174|Actinobacteria	201174|Actinobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRD3_k127_3180946_4	106370.Francci3_1615	1.916e-41	171.0	COG0716@1|root,COG0716@2|Bacteria,2IQZD@201174|Actinobacteria	201174|Actinobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Flavodoxin_5
SRD3_k127_3180946_3	1229780.BN381_10324	1.831e-76	282.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,3UWRM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRD3_k127_3180946_2	649831.L083_4709	4.27e-78	271.0	COG2021@1|root,COG2021@2|Bacteria,2I3NA@201174|Actinobacteria,4DMU9@85008|Micromonosporales	201174|Actinobacteria	E	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRD3_k127_3180946_0	1229780.BN381_10333	5.481e-155	511.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,3UWNW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
SRD3_k127_3180946_6	1120954.ATXE01000002_gene731	2.381e-28	119.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRD3_k127_3180946_5	1121877.JQKF01000010_gene695	3.917e-29	125.0	COG0477@1|root,COG2814@2|Bacteria,2GKRT@201174|Actinobacteria,4CN19@84992|Acidimicrobiia	84992|Acidimicrobiia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_3187121_1	487521.OCU_06360	1.734e-31	124.0	COG0451@1|root,COG0451@2|Bacteria,2GN2J@201174|Actinobacteria,2332V@1762|Mycobacteriaceae	201174|Actinobacteria	M	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
SRD3_k127_3187121_2	1229780.BN381_100221	6.465e-30	127.0	COG0735@1|root,COG0735@2|Bacteria	2|Bacteria	P	belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRD3_k127_3187121_0	398527.Bphyt_0292	8.622e-93	316.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,2VHKN@28216|Betaproteobacteria,1K0PR@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
SRD3_k127_3204355_6	1219084.AP014508_gene357	5.71e-15	85.0	COG0438@1|root,COG0438@2|Bacteria,2GC8C@200918|Thermotogae	200918|Thermotogae	M	PFAM glycosyl transferase group 1	mggS	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD3_k127_3204355_1	1229780.BN381_310045	1.644e-84	290.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,3UXA6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	4.2.1.149	ko:K08299	-	-	R10675	RC01095	ko00000,ko01000	-	-	-	ECH_1
SRD3_k127_3204355_0	324602.Caur_1119	9.326e-172	544.0	COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi,375CR@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRD3_k127_3204355_4	1121877.JQKF01000002_gene1731	4.595e-54	199.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4CNHE@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRD3_k127_3204355_3	1229780.BN381_310049	5.743e-60	214.0	COG1131@1|root,COG1131@2|Bacteria,2IRXJ@201174|Actinobacteria	201174|Actinobacteria	V	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
SRD3_k127_3204355_5	1313172.YM304_09610	1.92e-48	181.0	COG2386@1|root,COG2386@2|Bacteria,2HG7F@201174|Actinobacteria,4CN4H@84992|Acidimicrobiia	84992|Acidimicrobiia	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SRD3_k127_3204355_2	1121877.JQKF01000016_gene155	5.008e-71	253.0	COG0755@1|root,COG0755@2|Bacteria,2IIHK@201174|Actinobacteria,4CN1E@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SRD3_k127_3205967_11	1193181.BN10_520061	8.902e-06	55.0	COG0438@1|root,COG0438@2|Bacteria,2GMXE@201174|Actinobacteria,4FF5E@85021|Intrasporangiaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRD3_k127_3205967_4	525909.Afer_0742	1.139e-80	295.0	COG0438@1|root,COG0438@2|Bacteria,2GIVP@201174|Actinobacteria,4CN35@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD3_k127_3205967_6	1219045.BV98_003712	3.172e-55	198.0	COG0391@1|root,COG0391@2|Bacteria,1NK78@1224|Proteobacteria,2TUUA@28211|Alphaproteobacteria,2K3GV@204457|Sphingomonadales	204457|Sphingomonadales	S	LPPG Fo 2-phospho-L-lactate transferase	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRD3_k127_3205967_8	1229780.BN381_10187	1.438e-35	138.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRD3_k127_3205967_5	1229780.BN381_10186	4.197e-70	262.0	COG1478@1|root,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,3UXCJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	F420-0:Gamma-glutamyl ligase	fbiB	GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase,Nitroreductase
SRD3_k127_3205967_1	1287475.HMPREF1650_08535	1.212e-100	336.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria,22JS4@1653|Corynebacteriaceae	201174|Actinobacteria	M	4-epimerase	galE1	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRD3_k127_3205967_2	1229780.BN381_10183	6.688e-99	336.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,3UXFW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	JM	Nucleotidyl transferase	manC	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRD3_k127_3205967_9	525909.Afer_0737	3.414e-22	106.0	2968S@1|root,2ZTIT@2|Bacteria,2HEBZ@201174|Actinobacteria,4CNCH@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_3205967_7	1435356.Y013_07680	4.308e-55	212.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,4FUKN@85025|Nocardiaceae	201174|Actinobacteria	S	Glycosyltransferase like family 2	wbbL	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0045226,GO:0046379,GO:0071704,GO:0071944,GO:1901576	2.4.1.289	ko:K16870	-	-	-	-	ko00000,ko01000,ko01003	-	-	iNJ661.Rv3265c	Glyco_tranf_2_3,Glycos_transf_2
SRD3_k127_3205967_3	1229780.BN381_10136	1.341e-89	304.0	COG1091@1|root,COG1091@2|Bacteria,2GNY8@201174|Actinobacteria,3UWQ1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rmlD	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRD3_k127_3205967_0	1179773.BN6_57850	5.902e-161	517.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4E22V@85010|Pseudonocardiales	201174|Actinobacteria	M	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRD3_k127_3205967_10	1385521.N803_15920	2.3e-07	55.0	COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,4FGRU@85021|Intrasporangiaceae	201174|Actinobacteria	H	Biotin protein ligase C terminal domain	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
SRD3_k127_3217020_1	1394178.AWOO02000015_gene7055	7.416e-101	355.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4EHHR@85012|Streptosporangiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRD3_k127_3217020_3	1122138.AQUZ01000018_gene7511	3.763e-47	178.0	COG0454@1|root,COG0456@2|Bacteria,2IJPW@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD3_k127_3217020_5	1370125.AUWT01000063_gene891	7.597e-19	101.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,234RM@1762|Mycobacteriaceae	201174|Actinobacteria	V	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRD3_k127_3217020_2	710111.FraQA3DRAFT_1436	9.986e-50	191.0	2C7KP@1|root,32UAQ@2|Bacteria,2GMCX@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2889)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2889
SRD3_k127_3217020_0	1283287.KB822578_gene2556	1.296e-164	535.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
SRD3_k127_3217020_4	68170.KL590491_gene4722	6.059e-29	126.0	2FKRZ@1|root,34CCH@2|Bacteria,2H591@201174|Actinobacteria,4EB8F@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_3227070_2	525909.Afer_1819	5.806e-08	58.0	COG1826@1|root,COG1826@2|Bacteria,2HH2I@201174|Actinobacteria,4CP2H@84992|Acidimicrobiia	84992|Acidimicrobiia	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRD3_k127_3227070_0	29306.JOBE01000083_gene5538	6.769e-160	514.0	COG2015@1|root,COG2015@2|Bacteria,2H3T3@201174|Actinobacteria	201174|Actinobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
SRD3_k127_3227070_1	1449976.KALB_1963	4.87e-19	96.0	COG1622@1|root,COG1622@2|Bacteria,2GNXA@201174|Actinobacteria,4DXAI@85010|Pseudonocardiales	201174|Actinobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRD3_k127_3229585_1	1313172.YM304_15380	3.127e-67	233.0	COG3394@1|root,COG3394@2|Bacteria,2HG9M@201174|Actinobacteria,4CN7Z@84992|Acidimicrobiia	84992|Acidimicrobiia	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
SRD3_k127_3229585_2	987059.RBXJA2T_13839	1.491e-10	69.0	COG0640@1|root,COG0640@2|Bacteria,1R0XC@1224|Proteobacteria,2WHXS@28216|Betaproteobacteria	28216|Betaproteobacteria	K	STAS-like domain of unknown function (DUF4325)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4325
SRD3_k127_3229585_0	1120936.KB907209_gene1393	3.005e-125	415.0	COG2141@1|root,COG2141@2|Bacteria,2GN4N@201174|Actinobacteria,4EGV0@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_3235680_4	1227500.C494_13791	2.151e-29	128.0	COG0500@1|root,arCOG01783@2157|Archaea,2XWBW@28890|Euryarchaeota,23UCS@183963|Halobacteria	183963|Halobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRD3_k127_3235680_3	443218.AS9A_2066	3.182e-41	164.0	COG3832@1|root,COG3832@2|Bacteria,2IFJT@201174|Actinobacteria,238NR@1762|Mycobacteriaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRD3_k127_3235680_0	861299.J421_2243	1.011e-305	952.0	COG1523@1|root,COG1523@2|Bacteria,1ZV42@142182|Gemmatimonadetes	2|Bacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	glgX	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRD3_k127_3235680_1	479434.Sthe_1091	1.819e-278	899.0	COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi,27XZS@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRD3_k127_3235680_2	1121468.AUBR01000021_gene2827	8.698e-131	438.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,42FUX@68295|Thermoanaerobacterales	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRD3_k127_3238710_1	266117.Rxyl_0963	3.94e-129	432.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4CQKT@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.7.1,1.8.1.2	ko:K00366,ko:K00381	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRD3_k127_3238710_2	710686.Mycsm_04104	6.033e-63	224.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria,2345B@1762|Mycobacteriaceae	201174|Actinobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004604,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016667,GO:0016671,GO:0019344,GO:0019752,GO:0040007,GO:0043436,GO:0043866,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2392	PAPS_reduct
SRD3_k127_3238710_4	1313172.YM304_35060	4.456e-34	141.0	COG1648@1|root,COG1648@2|Bacteria,2GTES@201174|Actinobacteria	201174|Actinobacteria	H	TIGRFAM siroheme synthase	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
SRD3_k127_3238710_3	134676.ACPL_3478	4.228e-34	142.0	COG1846@1|root,COG1846@2|Bacteria,2IKZU@201174|Actinobacteria,4DJ1J@85008|Micromonosporales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRD3_k127_3238710_0	351607.Acel_1956	8.124e-152	486.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4ESAH@85013|Frankiales	201174|Actinobacteria	C	PFAM Aldehyde dehydrogenase	gabD1	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD3_k127_327194_1	345341.KUTG_00490	5.294e-31	125.0	COG5607@1|root,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria,4EAUR@85010|Pseudonocardiales	201174|Actinobacteria	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
SRD3_k127_327194_2	1313172.YM304_09680	3.542e-26	113.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	3.6.1.55	ko:K03574,ko:K08296	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRD3_k127_327194_0	443218.AS9A_4236	3.158e-66	231.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,234NT@1762|Mycobacteriaceae	201174|Actinobacteria	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRD3_k127_3319833_1	1229780.BN381_50026	7.395e-48	186.0	COG0438@1|root,COG0438@2|Bacteria,2GNIU@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRD3_k127_3319833_0	56110.Oscil6304_3543	2.51e-225	735.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRD3_k127_3319833_2	1146883.BLASA_0339	1.46e-43	175.0	28IEF@1|root,2Z8GG@2|Bacteria,2I8UG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_3319833_3	1123320.KB889607_gene9521	2.005e-09	70.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2GJ1Y@201174|Actinobacteria	201174|Actinobacteria	DM	biosynthesis protein	-	-	2.7.10.1	ko:K08252,ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,CbiA,Wzz
SRD3_k127_3329129_2	1463858.JOHR01000001_gene6186	5.777e-105	360.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria	2|Bacteria	E	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C
SRD3_k127_3329129_3	1380390.JIAT01000010_gene4351	2.503e-49	189.0	COG3511@1|root,COG3511@2|Bacteria,2II4P@201174|Actinobacteria	201174|Actinobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
SRD3_k127_3329129_4	414996.IL38_09090	6.766e-14	78.0	COG1550@1|root,COG1550@2|Bacteria,2IQW4@201174|Actinobacteria,409GA@622450|Actinopolysporales	201174|Actinobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRD3_k127_3329129_1	298654.FraEuI1c_4031	1.407e-121	412.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4ERV6@85013|Frankiales	201174|Actinobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRD3_k127_3329129_0	1173028.ANKO01000174_gene2705	4.745e-204	659.0	COG1501@1|root,COG1501@2|Bacteria,1G4DY@1117|Cyanobacteria,1HF3S@1150|Oscillatoriales	1117|Cyanobacteria	G	Galactose mutarotase-like	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,Gal_mutarotas_2,Glyco_hydro_31
SRD3_k127_3335759_2	645465.ACUR01000575_gene1381	5.939e-34	135.0	COG1788@1|root,COG2057@1|root,COG1788@2|Bacteria,COG2057@2|Bacteria,2I931@201174|Actinobacteria	201174|Actinobacteria	I	Coenzyme A transferase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_trans
SRD3_k127_3335759_1	402881.Plav_0280	7.145e-39	164.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,2VAZC@28211|Alphaproteobacteria,1JQKQ@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD3_k127_3335759_0	1206744.BAGL01000004_gene3646	2.824e-49	187.0	COG2084@1|root,COG2084@2|Bacteria,2GNI7@201174|Actinobacteria,4FVG5@85025|Nocardiaceae	201174|Actinobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRD3_k127_3335759_3	1206741.BAFX01000005_gene5886	7.525e-06	49.0	COG4221@1|root,COG4221@2|Bacteria,2I8VU@201174|Actinobacteria,4FVKU@85025|Nocardiaceae	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_3339728_0	1380390.JIAT01000013_gene145	3.413e-168	564.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,2GJRI@201174|Actinobacteria	201174|Actinobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
SRD3_k127_3347474_0	1116369.KB890026_gene5471	3.054e-173	563.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria,43IQC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRD3_k127_3347474_2	1144307.PMI04_03287	1.313e-70	248.0	COG1028@1|root,COG1028@2|Bacteria,1QDBJ@1224|Proteobacteria,2TV7A@28211|Alphaproteobacteria,2K9B8@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD3_k127_3347474_1	298655.KI912266_gene6068	1.875e-97	330.0	COG1028@1|root,COG1028@2|Bacteria,2GN6U@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRD3_k127_3347474_3	1333998.M2A_2787	1.627e-37	150.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2TRXY@28211|Alphaproteobacteria,4BSZR@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	MA20_19310	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRD3_k127_3377015_6	1150599.MPHLEI_14649	1.115e-15	77.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria,2359T@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_3377015_1	487521.OCU_08110	2.744e-131	430.0	COG1960@1|root,COG1960@2|Bacteria,2GK9U@201174|Actinobacteria,233DU@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_3377015_3	1150469.RSPPHO_00575	1.577e-37	160.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2TRVF@28211|Alphaproteobacteria,2JW7R@204441|Rhodospirillales	204441|Rhodospirillales	H	AMP-binding enzyme C-terminal domain	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
SRD3_k127_3377015_0	1343740.M271_44305	1.433e-162	541.0	COG0318@1|root,COG0318@2|Bacteria,2GMYS@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_3377015_2	1246995.AFR_04305	7.773e-79	289.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_3391632_1	1906.SFRA_13685	2.006e-98	335.0	2CDI5@1|root,2Z7ZQ@2|Bacteria,2I8FG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_3391632_0	448385.sce4495	1.528e-115	391.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,2YYE4@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD3_k127_3391632_2	557599.MKAN_27565	9.7e-75	257.0	COG1309@1|root,COG1309@2|Bacteria,2GXGA@201174|Actinobacteria,23BVI@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD3_k127_3391632_3	350054.Mflv_3340	0.000812	51.0	COG0183@1|root,COG0183@2|Bacteria,2I3PP@201174|Actinobacteria,232HJ@1762|Mycobacteriaceae	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
SRD3_k127_3417315_3	525909.Afer_1496	9.567e-35	136.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4CNVP@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF2469)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2469
SRD3_k127_3417315_4	471852.Tcur_3413	3.229e-24	111.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4EJZV@85012|Streptosporangiales	201174|Actinobacteria	L	Uncharacterised protein family UPF0102	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRD3_k127_3417315_2	1313172.YM304_18790	1.508e-89	302.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria,4CNAF@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRD3_k127_3417315_5	765912.Thimo_3445	4.184e-23	108.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,1RNSF@1236|Gammaproteobacteria,1WZQ1@135613|Chromatiales	135613|Chromatiales	F	other phosphorylase family 1	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRD3_k127_3417315_8	399739.Pmen_3648	1.128e-13	76.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CHASE,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3,TarH
SRD3_k127_3417315_7	309801.trd_1490	8.541e-14	77.0	COG1917@1|root,COG1917@2|Bacteria,2G9S4@200795|Chloroflexi,27ZAD@189775|Thermomicrobia	189775|Thermomicrobia	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD3_k127_3417315_1	326424.FRAAL1886	3.506e-92	318.0	COG0477@1|root,COG0477@2|Bacteria,2GKFJ@201174|Actinobacteria,4ERNW@85013|Frankiales	201174|Actinobacteria	EGP	Major facilitator superfamily	entS_1	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRD3_k127_3417315_0	1229780.BN381_330046	2.017e-142	474.0	COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria,3UWCB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRD3_k127_3417315_6	1380390.JIAT01000010_gene4268	1.065e-15	90.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,4CQDE@84995|Rubrobacteria	84995|Rubrobacteria	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRD3_k127_3445096_2	771875.Ferpe_0712	1.016e-07	65.0	COG1520@1|root,COG1520@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
SRD3_k127_3445096_1	134676.ACPL_3897	1.503e-56	222.0	COG0739@1|root,COG2755@1|root,COG3291@1|root,COG0739@2|Bacteria,COG2755@2|Bacteria,COG3291@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_3445096_0	483218.BACPEC_02327	1.087e-67	250.0	COG0438@1|root,COG0438@2|Bacteria,1TQRV@1239|Firmicutes,24E7I@186801|Clostridia	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRD3_k127_3445096_3	644282.Deba_0453	0.0001846	49.0	COG2227@1|root,COG2227@2|Bacteria,1MZEB@1224|Proteobacteria,43E9B@68525|delta/epsilon subdivisions,2WQYA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Methyltransferase domain	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	Methyltransf_11,Methyltransf_23
SRD3_k127_3469754_0	1313172.YM304_16400	3.49e-213	680.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4CMS5@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Zn-dependent metallo-hydrolase RNA specificity domain	-	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRD3_k127_3469754_2	1229780.BN381_80296	1.114e-100	336.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,3UWKM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRD3_k127_3469754_1	1229780.BN381_80295	2.587e-157	523.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
SRD3_k127_3469754_6	1229780.BN381_80294	1.878e-24	112.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD3_k127_3469754_3	1229780.BN381_330092	5.229e-89	301.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,3UWJR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRD3_k127_3469754_4	512565.AMIS_69530	1.794e-49	181.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4D8I3@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the peptidase M16 family	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRD3_k127_3486436_2	1449976.KALB_2975	1.867e-90	311.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4DZA5@85010|Pseudonocardiales	201174|Actinobacteria	K	Sir2 family	cobB2	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRD3_k127_3486436_3	215803.DB30_0464	2.829e-72	263.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42PT2@68525|delta/epsilon subdivisions	1224|Proteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRD3_k127_3486436_1	1380356.JNIK01000018_gene852	2.027e-131	461.0	COG0318@1|root,COG0318@2|Bacteria,2I916@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRD3_k127_3486436_0	146922.JOFU01000031_gene5937	4.025e-169	548.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD1	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009013,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD3_k127_3486436_5	35754.JNYJ01000101_gene9938	5.995e-35	147.0	COG1846@1|root,COG1846@2|Bacteria,2IKZU@201174|Actinobacteria,4DJ1J@85008|Micromonosporales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRD3_k127_3486436_4	644966.Tmar_1629	1.317e-35	144.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,3WCJ5@538999|Clostridiales incertae sedis	186801|Clostridia	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
SRD3_k127_3504471_4	28444.JODQ01000007_gene5890	3.75e-05	54.0	COG0577@1|root,COG0577@2|Bacteria,2GWZR@201174|Actinobacteria	2|Bacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
SRD3_k127_3504471_3	298655.KI912266_gene82	5.449e-19	93.0	COG2172@1|root,COG2172@2|Bacteria,2IIE8@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
SRD3_k127_3504471_1	367299.JOEE01000002_gene2603	1.246e-110	402.0	COG3000@1|root,COG3000@2|Bacteria,2GMF0@201174|Actinobacteria,4FGHB@85021|Intrasporangiaceae	201174|Actinobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRD3_k127_3504471_0	926560.KE387023_gene2049	7.172e-127	450.0	COG5001@1|root,COG5001@2|Bacteria,1WK20@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4
SRD3_k127_3504471_2	1283287.KB822577_gene3218	1.489e-96	331.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4DTUR@85009|Propionibacteriales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
SRD3_k127_3541637_5	1445613.JALM01000064_gene1363	0.0001119	52.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,4E2VH@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD3_k127_3541637_4	869210.Marky_1416	6.571e-12	78.0	2CP7W@1|root,32MRP@2|Bacteria,1WKBJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_3541637_0	1123023.JIAI01000002_gene5308	1.114e-134	447.0	COG1575@1|root,COG1575@2|Bacteria,2IPQ8@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRD3_k127_3541637_1	926560.KE387023_gene2049	5.943e-132	456.0	COG5001@1|root,COG5001@2|Bacteria,1WK20@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4
SRD3_k127_3541637_2	47839.CCAU010000011_gene5202	4.284e-62	219.0	COG2128@1|root,COG2128@2|Bacteria,2I9B5@201174|Actinobacteria,2384H@1762|Mycobacteriaceae	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRD3_k127_3541637_3	105425.BBPL01000059_gene5044	5.909e-56	205.0	arCOG03842@1|root,30WW9@2|Bacteria,2IDJ1@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF929
SRD3_k127_3551907_6	525909.Afer_1535	2.264e-19	88.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4CN6V@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRD3_k127_3551907_0	525909.Afer_1534	8.078e-227	713.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4CMTC@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRD3_k127_3551907_4	1229780.BN381_80132	1.609e-72	268.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,3UWGQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRD3_k127_3551907_1	1121877.JQKF01000003_gene1445	2.042e-215	683.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4CNJW@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRD3_k127_3551907_2	1313172.YM304_12700	2.773e-197	629.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4CMQA@84992|Acidimicrobiia	84992|Acidimicrobiia	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRD3_k127_3551907_3	105422.BBPM01000019_gene2652	9.555e-177	565.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,2NHQV@228398|Streptacidiphilus	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRD3_k127_3551907_5	351607.Acel_0114	9.69e-44	163.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4ERX6@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRD3_k127_3614026_1	1313172.YM304_20470	3.323e-34	151.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CN0R@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRD3_k127_3614026_0	1313172.YM304_20460	2.659e-212	673.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4CMUA@84992|Acidimicrobiia	84992|Acidimicrobiia	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRD3_k127_3621308_1	1121877.JQKF01000002_gene1700	1.009e-152	493.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CN7I@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Ribonucleotide reductase, barrel domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRD3_k127_3621308_0	1121877.JQKF01000002_gene1700	6.761e-250	782.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CN7I@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Ribonucleotide reductase, barrel domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRD3_k127_3621308_2	926560.KE387023_gene1152	2.157e-150	491.0	COG0554@1|root,COG0554@2|Bacteria,1WI6Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRD3_k127_3621308_3	1133849.O3I_003445	5.198e-27	111.0	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria,4G2BY@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
SRD3_k127_3638246_1	1121877.JQKF01000001_gene1349	1.516e-66	231.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4CMS3@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRD3_k127_3638246_0	525909.Afer_0730	3.589e-155	495.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4CMS3@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRD3_k127_3638246_2	469371.Tbis_0702	1.428e-26	114.0	COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,4E356@85010|Pseudonocardiales	201174|Actinobacteria	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
SRD3_k127_3652241_0	1313172.YM304_37800	6.07e-109	358.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,4CMV9@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRD3_k127_3652241_1	525909.Afer_0253	3.637e-75	261.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4CMTZ@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD3_k127_3658083_0	298653.Franean1_2532	1.328e-122	401.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4EUCH@85013|Frankiales	201174|Actinobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRD3_k127_3658083_2	1121877.JQKF01000026_gene2437	1.192e-48	181.0	arCOG04740@1|root,31PZA@2|Bacteria,2GP15@201174|Actinobacteria,4CNIC@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_3658083_1	1089544.KB912942_gene1783	6.065e-80	281.0	COG1073@1|root,COG1073@2|Bacteria,2IFI1@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRD3_k127_3658083_3	339670.Bamb_1622	1.681e-05	50.0	28M8C@1|root,2ZAMI@2|Bacteria,1R981@1224|Proteobacteria,2W6T7@28216|Betaproteobacteria,1KCKR@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_367996_3	1120950.KB892707_gene4989	3.525e-66	233.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4DNYP@85009|Propionibacteriales	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRD3_k127_367996_0	1229780.BN381_10176	6.056e-147	479.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,3UW6R@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	UDP binding domain	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRD3_k127_367996_1	66377.JOBH01000002_gene708	1.921e-122	411.0	COG0451@1|root,COG0451@2|Bacteria,2I2EG@201174|Actinobacteria	201174|Actinobacteria	GM	epimerase dehydratase	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRD3_k127_367996_2	1382356.JQMP01000004_gene670	1.712e-75	274.0	COG1215@1|root,COG1215@2|Bacteria,2G6BS@200795|Chloroflexi,27Y06@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD3_k127_3694771_0	1313172.YM304_19820	2.39e-144	462.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4CMSX@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRD3_k127_3694771_5	1210046.B277_08285	1.681e-67	235.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4FG85@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRD3_k127_3694771_3	525909.Afer_1219	8.238e-100	340.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CMY7@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRD3_k127_3694771_7	1313172.YM304_19860	4.117e-40	155.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4CNAX@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRD3_k127_3694771_6	1229780.BN381_50109	1.875e-40	164.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,3UWUJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRD3_k127_3694771_1	1313172.YM304_19880	9.157e-136	454.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4CMVN@84992|Acidimicrobiia	84992|Acidimicrobiia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRD3_k127_3694771_8	1121861.KB899922_gene3187	4.225e-12	72.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria,2JT97@204441|Rhodospirillales	204441|Rhodospirillales	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRD3_k127_3694771_2	1121877.JQKF01000002_gene1672	2.619e-121	410.0	COG0342@1|root,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4CMXX@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
SRD3_k127_3694771_4	1121877.JQKF01000002_gene1673	7.509e-92	316.0	COG0341@1|root,COG0341@2|Bacteria,2GJRS@201174|Actinobacteria,4CMYT@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRD3_k127_3697099_6	326424.FRAAL6288	2.914e-35	143.0	COG1434@1|root,COG1434@2|Bacteria,2IMCB@201174|Actinobacteria	201174|Actinobacteria	S	Gram-negative-bacterium-type cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRD3_k127_3697099_3	479432.Sros_8959	2.41e-55	203.0	COG0500@1|root,COG2226@2|Bacteria,2IP4P@201174|Actinobacteria,4EKAN@85012|Streptosporangiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRD3_k127_3697099_0	37919.EP51_05675	2.563e-132	435.0	COG2227@1|root,COG2227@2|Bacteria,2GM7A@201174|Actinobacteria,4FZQY@85025|Nocardiaceae	201174|Actinobacteria	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
SRD3_k127_3697099_2	390989.JOEG01000003_gene4425	1.232e-81	278.0	COG1218@1|root,COG1218@2|Bacteria,2GMW7@201174|Actinobacteria,4DA74@85008|Micromonosporales	201174|Actinobacteria	P	Inositol monophosphatase	cysQ_1	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
SRD3_k127_3697099_1	247633.GP2143_09295	2.697e-126	421.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,1RP33@1236|Gammaproteobacteria,1J6AR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRD3_k127_3697099_7	1172185.KB911512_gene4863	1.064e-28	132.0	COG0346@1|root,COG0346@2|Bacteria,2H8GV@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
SRD3_k127_3697099_8	1340493.JNIF01000003_gene2259	4.946e-25	116.0	COG2230@1|root,COG2230@2|Bacteria,3Y9AA@57723|Acidobacteria	57723|Acidobacteria	M	DREV methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRD3_k127_3697099_5	1313172.YM304_22270	6.567e-39	161.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRD3_k127_3697099_4	1313172.YM304_22260	1.446e-48	181.0	COG0560@1|root,COG3320@1|root,COG0560@2|Bacteria,COG3320@2|Bacteria,2GJVX@201174|Actinobacteria,4CMQQ@84992|Acidimicrobiia	84992|Acidimicrobiia	EQ	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,NAD_binding_4
SRD3_k127_3700309_1	266117.Rxyl_0940	1.45e-13	81.0	COG1595@1|root,COG1595@2|Bacteria,2HG2Y@201174|Actinobacteria,4CTJS@84995|Rubrobacteria	84995|Rubrobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
SRD3_k127_3700309_0	644283.Micau_3030	6.14e-56	205.0	COG1948@1|root,COG4880@2|Bacteria,2I8JU@201174|Actinobacteria,4D8V4@85008|Micromonosporales	201174|Actinobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
SRD3_k127_3705472_0	1510531.JQJJ01000008_gene4006	1.954e-24	117.0	COG1215@1|root,COG1215@2|Bacteria,1RIJ7@1224|Proteobacteria,2TXPS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD3_k127_3705472_1	1089550.ATTH01000001_gene525	9.827e-24	111.0	COG0438@1|root,COG0438@2|Bacteria,4NXGU@976|Bacteroidetes	976|Bacteroidetes	M	Exostosin family	-	-	-	-	-	-	-	-	-	-	-	-	Exostosin
SRD3_k127_3715269_0	58123.JOFJ01000003_gene2208	9.173e-73	251.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4EFPE@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	1.14.13.141	ko:K15981	ko00984,ko01120,map00984,map01120	-	R09859,R11357	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRD3_k127_3715269_2	390989.JOEG01000011_gene199	1.755e-14	86.0	COG1309@1|root,COG1309@2|Bacteria,2GJZJ@201174|Actinobacteria,4DJ04@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD3_k127_3715269_1	675635.Psed_4102	6.884e-24	108.0	2DNW5@1|root,32ZGI@2|Bacteria,2IQ5T@201174|Actinobacteria,4ECM0@85010|Pseudonocardiales	201174|Actinobacteria	S	Rho termination factor	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
SRD3_k127_3717514_0	1121946.AUAX01000002_gene401	3.568e-100	336.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,4DI0B@85008|Micromonosporales	201174|Actinobacteria	E	3-dehydroquinate synthase	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829,ko:K16020	ko00400,ko01051,ko01100,ko01110,ko01130,ko01230,map00400,map01051,map01100,map01110,map01130,map01230	M00022	R02412,R03083,R06592	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRD3_k127_3717514_1	1229780.BN381_50135	5.467e-55	200.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,3UWWA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786,ko:K16021	ko00400,ko01051,ko01100,ko01110,ko01130,ko01230,map00400,map01051,map01100,map01110,map01130,map01230	M00022	R03084,R06593	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRD3_k127_3719635_7	1313172.YM304_10780	4.677e-38	147.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4CMYQ@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRD3_k127_3719635_0	365528.KB891227_gene309	7.291e-255	801.0	COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4EREC@85013|Frankiales	201174|Actinobacteria	G	Trehalose synthase	treS	GO:0000023,GO:0000271,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016160,GO:0016161,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0047471,GO:0055114,GO:0071704,GO:0071944,GO:1901576	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	iNJ661.Rv0126	Alpha-amylase,Malt_amylase_C
SRD3_k127_3719635_8	1449976.KALB_7505	3.493e-37	158.0	COG3281@1|root,COG3281@2|Bacteria,2GKAP@201174|Actinobacteria,4E0QY@85010|Pseudonocardiales	201174|Actinobacteria	G	protein, probably involved in trehalose biosynthesis	mak	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576	2.7.1.175	ko:K16146	ko00500,ko01100,map00500,map01100	-	R09945	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
SRD3_k127_3719635_2	479432.Sros_2755	2.76e-134	436.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4EGVD@85012|Streptosporangiales	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRD3_k127_3719635_3	525909.Afer_0499	1.581e-133	434.0	COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,4CMV6@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Domain of unknown function (DUF4921)	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
SRD3_k127_3719635_5	1313172.YM304_12550	2.544e-103	347.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4CN5Q@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRD3_k127_3719635_9	1121918.ARWE01000001_gene3107	5.396e-18	100.0	COG2199@1|root,COG3706@2|Bacteria,1N7HG@1224|Proteobacteria,43AY4@68525|delta/epsilon subdivisions,2X6CH@28221|Deltaproteobacteria	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRD3_k127_3719635_4	1229780.BN381_10079	1.764e-106	359.0	COG0482@1|root,COG0482@2|Bacteria,2GIUQ@201174|Actinobacteria,3UW6U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRD3_k127_3719635_6	1128421.JAGA01000002_gene1815	4.272e-50	186.0	COG0272@1|root,COG0272@2|Bacteria,2NNSW@2323|unclassified Bacteria	2|Bacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRD3_k127_3719635_1	1313172.YM304_12590	1.447e-158	511.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4CMSH@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRD3_k127_3722183_4	1229780.BN381_150069	1.569e-43	161.0	COG2185@1|root,COG2185@2|Bacteria,2I2N3@201174|Actinobacteria,3UX6U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	B12 binding domain	meaA	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRD3_k127_3722183_1	1381751.JAJB01000030_gene1148	2.714e-115	390.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4F8SH@85019|Brevibacteriaceae	201174|Actinobacteria	S	ATPases associated with a variety of cellular activities	ybiT	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn,DLIC
SRD3_k127_3722183_0	525909.Afer_0231	2.924e-281	874.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CMPB@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRD3_k127_3722183_3	298655.KI912266_gene5565	3.337e-76	270.0	COG0411@1|root,COG0411@2|Bacteria,2H5WA@201174|Actinobacteria	201174|Actinobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRD3_k127_3722183_2	1121272.KB903292_gene3945	7.325e-87	301.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4D8XW@85008|Micromonosporales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRD3_k127_3727454_2	479434.Sthe_2695	2.033e-59	222.0	COG5001@1|root,COG5001@2|Bacteria,2G7UT@200795|Chloroflexi,27Y1B@189775|Thermomicrobia	189775|Thermomicrobia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3
SRD3_k127_3727454_1	211114.JOEF01000013_gene4899	3.13e-86	302.0	COG2271@1|root,COG2271@2|Bacteria,2I2F7@201174|Actinobacteria,4DXJS@85010|Pseudonocardiales	201174|Actinobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_3727454_0	1121877.JQKF01000001_gene1297	4.712e-91	307.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CMRD@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRD3_k127_3730097_2	1463857.JOFZ01000001_gene5744	1.106e-14	76.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRD3_k127_3730097_3	1408424.JHYI01000029_gene4009	1.739e-08	64.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HFPF@91061|Bacilli,1ZF6G@1386|Bacillus	91061|Bacilli	T	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)	rsbW	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRD3_k127_3730097_1	1961.JOAK01000005_gene280	8.081e-72	258.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	sigF	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD3_k127_3730097_0	1455608.JDTH01000006_gene2659	3.351e-102	362.0	COG0475@1|root,COG0589@1|root,arCOG00449@2157|Archaea,arCOG01953@2157|Archaea,2XV77@28890|Euryarchaeota,23U1Z@183963|Halobacteria	183963|Halobacteria	P	COG0475 Kef-type K transport systems, membrane components	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
SRD3_k127_3770361_9	383372.Rcas_3678	0.0001268	44.0	COG1028@1|root,COG1028@2|Bacteria,2G660@200795|Chloroflexi,376R3@32061|Chloroflexia	32061|Chloroflexia	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_3770361_4	42256.RradSPS_0763	1.176e-94	320.0	COG0842@1|root,COG0842@2|Bacteria,2IPQ3@201174|Actinobacteria,4CT8V@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRD3_k127_3770361_3	266117.Rxyl_1742	5.236e-112	370.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CP6S@84995|Rubrobacteria	84995|Rubrobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRD3_k127_3770361_0	479433.Caci_5194	1.686e-142	463.0	COG2042@1|root,COG3376@2|Bacteria,2GJZB@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
SRD3_k127_3770361_1	101510.RHA1_ro02476	1.143e-133	454.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,4FV9U@85025|Nocardiaceae	201174|Actinobacteria	M	COG3511 Phospholipase C	plc	GO:0003674,GO:0003824,GO:0004620,GO:0004629,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006629,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009405,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0034480,GO:0035821,GO:0042578,GO:0044003,GO:0044238,GO:0044403,GO:0044419,GO:0044464,GO:0051701,GO:0051704,GO:0051817,GO:0052008,GO:0052043,GO:0052111,GO:0052185,GO:0052188,GO:0052368,GO:0071704,GO:0071944,GO:1901575	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	iNJ661.Rv1755c	Phosphoesterase
SRD3_k127_3770361_7	103733.JNYO01000006_gene1756	8.389e-39	167.0	COG3642@1|root,COG3642@2|Bacteria,2ICN3@201174|Actinobacteria,4E31Z@85010|Pseudonocardiales	201174|Actinobacteria	T	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRD3_k127_3770361_6	543632.JOJL01000011_gene7033	3.699e-78	284.0	COG2010@1|root,COG2010@2|Bacteria,2GN1Q@201174|Actinobacteria,4D9F8@85008|Micromonosporales	201174|Actinobacteria	C	Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,Cu2_monooxygen
SRD3_k127_3770361_2	1449048.JQKU01000006_gene4905	2.107e-116	387.0	COG2141@1|root,COG2141@2|Bacteria,2GKPX@201174|Actinobacteria,2335G@1762|Mycobacteriaceae	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_3770361_5	487521.OCU_01310	4.121e-85	291.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,236R5@1762|Mycobacteriaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_3787806_0	1313172.YM304_20720	3.778e-168	554.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GMFD@201174|Actinobacteria,4CMUN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRD3_k127_3787806_1	351607.Acel_1986	4.262e-50	197.0	COG1999@1|root,COG1999@2|Bacteria	2|Bacteria	M	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	AhpC-TSA,SCO1-SenC
SRD3_k127_3787806_2	391037.Sare_0186	2.349e-43	175.0	COG1276@1|root,COG3336@1|root,COG1276@2|Bacteria,COG3336@2|Bacteria,2GKIR@201174|Actinobacteria,4DBZV@85008|Micromonosporales	201174|Actinobacteria	P	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG,CopD
SRD3_k127_3805393_0	1048339.KB913029_gene4992	1.917e-65	231.0	COG0410@1|root,COG0410@2|Bacteria,2H3MJ@201174|Actinobacteria,4EX5S@85013|Frankiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRD3_k127_3805393_2	1121272.KB903292_gene3944	1.233e-05	59.0	2BMGV@1|root,32G1K@2|Bacteria,2IP6V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_3805393_1	68170.KL590474_gene6040	3.48e-10	74.0	2B1ET@1|root,31TVH@2|Bacteria,2GT2S@201174|Actinobacteria,4EBC4@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_3811380_4	1229780.BN381_150088	3.949e-41	157.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,2II8H@201174|Actinobacteria,3UWMP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRD3_k127_3811380_2	1121877.JQKF01000035_gene1966	1.986e-67	243.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CN2D@84992|Acidimicrobiia	84992|Acidimicrobiia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRD3_k127_3811380_1	1048339.KB913029_gene2297	1.605e-103	357.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,4ERXA@85013|Frankiales	201174|Actinobacteria	L	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
SRD3_k127_3811380_0	1313172.YM304_37070	2.876e-129	434.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4CNUD@84992|Acidimicrobiia	84992|Acidimicrobiia	O	KaiC	-	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase
SRD3_k127_3811380_3	525909.Afer_1903	3.427e-47	172.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4CMPF@84992|Acidimicrobiia	84992|Acidimicrobiia	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRD3_k127_3903984_1	1229780.BN381_170035	2.174e-148	488.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRD3_k127_3903984_0	1313172.YM304_19020	5.599e-150	492.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4CMTY@84992|Acidimicrobiia	201174|Actinobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRD3_k127_3909455_0	867903.ThesuDRAFT_00352	1.396e-193	626.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3WD0A@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
SRD3_k127_3909455_1	105422.BBPM01000051_gene1495	4.431e-73	250.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,2NF0X@228398|Streptacidiphilus	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD3_k127_3914949_3	1030157.AFMP01000011_gene3728	0.0003668	48.0	COG4221@1|root,COG4221@2|Bacteria,1NR0X@1224|Proteobacteria,2UTRZ@28211|Alphaproteobacteria,2K6DS@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_3914949_1	298654.FraEuI1c_3990	3.173e-124	431.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ES6E@85013|Frankiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_3914949_2	448385.sce5175	4.779e-70	263.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRD3_k127_3914949_0	710686.Mycsm_00756	1.148e-169	538.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,235XV@1762|Mycobacteriaceae	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRD3_k127_3915023_0	1449976.KALB_7925	3.76e-132	434.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4DXK5@85010|Pseudonocardiales	201174|Actinobacteria	M	glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
SRD3_k127_3915023_1	1445613.JALM01000013_gene1948	1.358e-99	338.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4DXK5@85010|Pseudonocardiales	201174|Actinobacteria	M	glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
SRD3_k127_3921537_3	479432.Sros_3246	8.557e-19	101.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4EFM3@85012|Streptosporangiales	201174|Actinobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRD3_k127_3921537_1	1206731.BAGB01000172_gene279	1.395e-66	244.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_3921537_0	1313172.YM304_00280	8.495e-171	547.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_3921537_2	675635.Psed_4420	6.848e-56	203.0	COG4119@1|root,COG4119@2|Bacteria,2IM6D@201174|Actinobacteria,4E45T@85010|Pseudonocardiales	201174|Actinobacteria	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRD3_k127_3930454_3	1229780.BN381_330012	3.523e-40	156.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,3UWU4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRD3_k127_3930454_1	525909.Afer_1514	3.468e-53	201.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4CN4E@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRD3_k127_3930454_2	1313172.YM304_18600	2.145e-42	163.0	COG0711@1|root,COG0711@2|Bacteria,2HG9T@201174|Actinobacteria,4CN89@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_3930454_4	1313172.YM304_18630	4.925e-29	128.0	COG1399@1|root,COG1399@2|Bacteria,2HGH0@201174|Actinobacteria,4CNEE@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRD3_k127_3930454_5	1313172.YM304_18640	3.056e-18	86.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRD3_k127_3930454_0	1313172.YM304_18650	4.367e-85	293.0	COG0416@1|root,COG0416@2|Bacteria,2I8WT@201174|Actinobacteria,4CMRM@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRD3_k127_3952740_0	479433.Caci_8515	3.496e-87	298.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria	201174|Actinobacteria	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRD3_k127_3952740_1	653045.Strvi_6126	1.517e-83	293.0	COG2070@1|root,COG2070@2|Bacteria,2IN9Q@201174|Actinobacteria	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRD3_k127_3952740_2	1394178.AWOO02000016_gene6846	6.7e-51	192.0	COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria,4ER9I@85012|Streptosporangiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD3_k127_3952740_3	105422.BBPM01000094_gene5281	1.12e-37	160.0	2E39M@1|root,32Y96@2|Bacteria,2IITE@201174|Actinobacteria,2NJ8S@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_3952740_4	1123508.JH636452_gene7032	1.191e-37	151.0	COG0642@1|root,COG2205@2|Bacteria,2IYV4@203682|Planctomycetes	203682|Planctomycetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRD3_k127_4000618_2	935839.JAGJ01000001_gene1033	6.327e-06	51.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria,4F4CP@85017|Promicromonosporaceae	201174|Actinobacteria	S	Hydrolase of the alpha beta-hydrolase	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
SRD3_k127_4000618_1	267608.RSp0380	6.186e-38	158.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KC61@119060|Burkholderiaceae	28216|Betaproteobacteria	T	signal transduction protein eal-ggdef domains	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9
SRD3_k127_4000618_0	247490.KSU1_D0048	9.801e-41	167.0	COG4191@1|root,COG4191@2|Bacteria,2IZZK@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRD3_k127_4042745_3	525909.Afer_0338	6.417e-08	56.0	COG1225@1|root,COG1225@2|Bacteria,2HGRA@201174|Actinobacteria,4CNTT@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Redoxin	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
SRD3_k127_4042745_1	1089546.AQUI01000002_gene3231	3.885e-14	80.0	COG3088@1|root,COG3088@2|Bacteria,2GTYU@201174|Actinobacteria	201174|Actinobacteria	P	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
SRD3_k127_4042745_0	351607.Acel_0046	1.48e-33	131.0	2EBEI@1|root,335F5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_404982_2	1123024.AUII01000002_gene844	3.011e-31	133.0	COG1695@1|root,COG1695@2|Bacteria,2GMJM@201174|Actinobacteria,4E1NG@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRD3_k127_404982_0	1121877.JQKF01000017_gene209	8.033e-187	591.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4CNE8@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Myo-inositol-1-phosphate synthase	ino1	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRD3_k127_404982_1	33898.JRHJ01000076_gene463	1.254e-161	525.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria	201174|Actinobacteria	J	tRNA nucleotidyltransferase poly(A) polymerase	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRD3_k127_410599_2	1229780.BN381_310065	8.854e-51	185.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria	201174|Actinobacteria	D	Pfam Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRD3_k127_410599_0	1229780.BN381_310066	5.313e-142	469.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria	201174|Actinobacteria	D	anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRD3_k127_410599_3	512565.AMIS_67620	4.091e-48	188.0	COG2199@1|root,COG2199@2|Bacteria,2IIAD@201174|Actinobacteria,4DIGT@85008|Micromonosporales	201174|Actinobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
SRD3_k127_410599_1	525909.Afer_0351	1.721e-102	351.0	COG1387@1|root,COG1387@2|Bacteria,2IR14@201174|Actinobacteria,4CNF5@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Histidinol phosphate phosphatase, HisJ	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRD3_k127_410599_4	1313172.YM304_09850	6.337e-48	193.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4CMRV@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Histidine kinase	-	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2
SRD3_k127_4123343_0	1133849.O3I_013415	6.447e-77	260.0	COG3832@1|root,COG3832@2|Bacteria,2I45V@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRD3_k127_4123343_2	1223545.GS4_37_00060	1.714e-30	130.0	COG2050@1|root,COG2050@2|Bacteria,2IMN9@201174|Actinobacteria,4GEHF@85026|Gordoniaceae	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRD3_k127_4123343_1	103733.JNYO01000008_gene5647	1.32e-40	162.0	COG1131@1|root,COG1131@2|Bacteria,2I2I7@201174|Actinobacteria,4E26W@85010|Pseudonocardiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD3_k127_412338_0	931627.MycrhDRAFT_5437	7.083e-78	265.0	COG0451@1|root,COG0451@2|Bacteria,2GN2J@201174|Actinobacteria,2332V@1762|Mycobacteriaceae	201174|Actinobacteria	M	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
SRD3_k127_412338_1	1415166.NONO_c00610	5.926e-56	206.0	COG1595@1|root,COG1595@2|Bacteria,2II44@201174|Actinobacteria,4G8T9@85025|Nocardiaceae	201174|Actinobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRD3_k127_412338_2	1048339.KB913029_gene4768	1.901e-48	189.0	COG2764@1|root,COG3324@1|root,COG2764@2|Bacteria,COG3324@2|Bacteria,2GMZD@201174|Actinobacteria,4EVHP@85013|Frankiales	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRD3_k127_412338_4	1499967.BAYZ01000058_gene4744	5.886e-31	137.0	COG0673@1|root,COG0673@2|Bacteria,2NRVS@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRD3_k127_412338_3	526226.Gbro_4603	6.911e-39	153.0	COG1309@1|root,COG1309@2|Bacteria,2GNK4@201174|Actinobacteria,4GCS0@85026|Gordoniaceae	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRD3_k127_412338_5	875328.JDM601_3596	7.273e-18	94.0	COG1024@1|root,COG1024@2|Bacteria,2GNTG@201174|Actinobacteria,234C8@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA8_6	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD3_k127_4133764_0	351607.Acel_1142	3.895e-136	447.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4ERSA@85013|Frankiales	201174|Actinobacteria	V	ABC transporter, transmembrane region	msbA	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRD3_k127_4133764_1	345341.KUTG_06993	2.11e-26	112.0	COG1846@1|root,COG1846@2|Bacteria,2IHP0@201174|Actinobacteria,4E7D4@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRD3_k127_4141348_2	1313172.YM304_15380	1.056e-28	119.0	COG3394@1|root,COG3394@2|Bacteria,2HG9M@201174|Actinobacteria,4CN7Z@84992|Acidimicrobiia	84992|Acidimicrobiia	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
SRD3_k127_4141348_3	7159.AAEL007023-PA	6.991e-05	54.0	COG2030@1|root,KOG4170@1|root,KOG1206@2759|Eukaryota,KOG4170@2759|Eukaryota,38D3K@33154|Opisthokonta,3CP3C@33208|Metazoa,3E57J@33213|Bilateria,41V77@6656|Arthropoda,3SFUX@50557|Insecta,44Z4F@7147|Diptera,45F9A@7148|Nematocera	33208|Metazoa	Q	N-terminal half of MaoC dehydratase	HSD17B4	GO:0001676,GO:0002376,GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005778,GO:0005782,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006699,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006886,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008209,GO:0008210,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0010817,GO:0015031,GO:0015833,GO:0016020,GO:0016042,GO:0016043,GO:0016053,GO:0016054,GO:0016229,GO:0016491,GO:0016508,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0030258,GO:0031090,GO:0031903,GO:0031907,GO:0031974,GO:0032787,GO:0033036,GO:0033365,GO:0033540,GO:0033559,GO:0033764,GO:0033865,GO:0033875,GO:0033989,GO:0034032,GO:0034440,GO:0034613,GO:0034641,GO:0034754,GO:0035337,GO:0035383,GO:0036109,GO:0036111,GO:0036112,GO:0042445,GO:0042579,GO:0042742,GO:0042802,GO:0042803,GO:0042886,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044594,GO:0045087,GO:0045184,GO:0046394,GO:0046395,GO:0046483,GO:0046907,GO:0046983,GO:0050829,GO:0050896,GO:0051179,GO:0051186,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0051707,GO:0055086,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072330,GO:0072521,GO:0072594,GO:0072662,GO:0072663,GO:0080023,GO:0098542,GO:0098588,GO:0098805,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901568,GO:1901575,GO:1901576,GO:1901615,GO:1901617	1.1.1.35,4.2.1.107,4.2.1.119	ko:K12405	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R04809,R04810,R04812,R04813,R09698	RC00089,RC00770,RC01217	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas,SCP2,adh_short
SRD3_k127_4141348_0	1313172.YM304_15360	4.135e-93	314.0	COG2120@1|root,COG2120@2|Bacteria,2H2NY@201174|Actinobacteria,4CN0C@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GlcNAc-PI de-N-acetylase	-	-	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRD3_k127_4141348_1	463191.SSEG_05963	1.418e-63	226.0	COG1842@1|root,COG1842@2|Bacteria,2GP0K@201174|Actinobacteria	201174|Actinobacteria	KT	Phage shock protein A	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRD3_k127_415591_4	1007103.AFHW01000053_gene3469	2.247e-38	150.0	COG0110@1|root,COG0110@2|Bacteria,1VCP6@1239|Firmicutes,4HNUA@91061|Bacilli,26YGK@186822|Paenibacillaceae	91061|Bacilli	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRD3_k127_415591_3	1313172.YM304_23740	1.915e-40	166.0	COG0406@1|root,COG0406@2|Bacteria,2IAPP@201174|Actinobacteria	201174|Actinobacteria	G	Histidine phosphatase superfamily (branch 1)	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRD3_k127_415591_0	1313172.YM304_23520	1.28e-203	649.0	COG3552@1|root,COG3825@1|root,COG3552@2|Bacteria,COG3825@2|Bacteria,2GNTS@201174|Actinobacteria,4CMU1@84992|Acidimicrobiia	84992|Acidimicrobiia	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRD3_k127_415591_2	1229780.BN381_10219	1.229e-128	424.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,3UX3U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRD3_k127_415591_1	525909.Afer_0782	3.177e-131	427.0	COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4CNAA@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD3_k127_4161465_0	1487953.JMKF01000053_gene1896	2.18e-100	338.0	COG3733@1|root,COG3733@2|Bacteria,1G2YB@1117|Cyanobacteria,1HE6W@1150|Oscillatoriales	1117|Cyanobacteria	Q	Copper amine oxidase, enzyme domain	-	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
SRD3_k127_4173756_0	436229.JOEH01000006_gene2870	2.958e-57	218.0	COG1075@1|root,COG1075@2|Bacteria,2GM7V@201174|Actinobacteria,2NFS9@228398|Streptacidiphilus	201174|Actinobacteria	S	Lipase (class 2)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_2
SRD3_k127_4173756_2	105420.BBPO01000046_gene1014	4.272e-10	63.0	COG3631@1|root,COG3631@2|Bacteria,2HYIS@201174|Actinobacteria,2NMPH@228398|Streptacidiphilus	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRD3_k127_4173756_1	1035308.AQYY01000001_gene1750	1.095e-14	88.0	2CUM0@1|root,32SVJ@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3263
SRD3_k127_4173756_3	1944.JOAZ01000006_gene664	4.129e-05	48.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria,4197N@629295|Streptomyces griseus group	201174|Actinobacteria	G	Trehalose-phosphatase	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRD3_k127_4194417_1	525909.Afer_1678	6.242e-71	246.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4CMZR@84992|Acidimicrobiia	84992|Acidimicrobiia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRD3_k127_4194417_5	1120917.AQXM01000063_gene2116	3.32e-12	70.0	COG0291@1|root,COG0291@2|Bacteria,2GQZW@201174|Actinobacteria,1W9Z4@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRD3_k127_4194417_4	1121877.JQKF01000023_gene2233	3.296e-46	170.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4CN4X@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRD3_k127_4194417_3	479432.Sros_6084	1.05e-46	181.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4EH5S@85012|Streptosporangiales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SRD3_k127_4194417_0	1121877.JQKF01000023_gene2231	5.717e-113	374.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,4CMPG@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRD3_k127_4194417_2	1229780.BN381_290127	4.204e-50	185.0	COG0072@1|root,COG0072@2|Bacteria,2GMFD@201174|Actinobacteria,3UW7Y@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRD3_k127_4197482_0	1313172.YM304_27700	3.583e-91	318.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4CMXE@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRD3_k127_4197482_2	1172180.KB911800_gene3354	2.403e-37	153.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria	201174|Actinobacteria	S	Metal-dependent hydrolases of the beta-lactamase superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRD3_k127_4197482_1	1313172.YM304_27710	8.66e-38	146.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4CN3V@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRD3_k127_4198127_0	326424.FRAAL6024	2.457e-129	430.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4ERKP@85013|Frankiales	201174|Actinobacteria	H	PFAM Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD3_k127_4198127_1	1048339.KB913029_gene3549	7.261e-127	412.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4ERRA@85013|Frankiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.19,1.2.1.8	ko:K00130,ko:K00137	ko00260,ko00330,ko00410,ko01100,map00260,map00330,map00410,map01100	M00555	R02549,R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD3_k127_4204882_1	1121877.JQKF01000022_gene2301	1.969e-283	888.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4CMUT@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRD3_k127_4204882_12	1120941.AUBL01000022_gene281	3.341e-16	87.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,4D66N@85005|Actinomycetales	201174|Actinobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRD3_k127_4204882_13	935866.JAER01000037_gene578	1.123e-08	64.0	COG2013@1|root,COG2013@2|Bacteria,2GSX6@201174|Actinobacteria,4DPJ8@85009|Propionibacteriales	201174|Actinobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24,DUF2510
SRD3_k127_4204882_8	1229780.BN381_10276	7.441e-62	226.0	COG1466@1|root,COG1466@2|Bacteria	2|Bacteria	L	DNA-directed DNA polymerase activity	holA	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
SRD3_k127_4204882_6	525909.Afer_1304	7.589e-91	306.0	COG0294@1|root,COG0294@2|Bacteria,2GJNI@201174|Actinobacteria,4CNF4@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Pterin binding enzyme	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRD3_k127_4204882_7	1313172.YM304_20990	3.871e-75	261.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria,4CMY0@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Tetratricopeptide repeat	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_20,Thioredoxin
SRD3_k127_4204882_5	1229780.BN381_10252	1.087e-103	358.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria,3UX9P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRD3_k127_4204882_9	1229780.BN381_10251	1.478e-58	214.0	COG2047@1|root,COG2047@2|Bacteria,2GK8I@201174|Actinobacteria	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRD3_k127_4204882_2	1313172.YM304_20970	8.275e-135	437.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_4204882_0	525909.Afer_1322	0.0	1055.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4CMQM@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
SRD3_k127_4204882_11	1283299.AUKG01000003_gene576	1.795e-19	101.0	2DPU0@1|root,333DA@2|Bacteria,2HPPH@201174|Actinobacteria,4CR26@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4204882_4	1476876.JOJO01000028_gene3640	2.589e-108	361.0	COG1064@1|root,COG1064@2|Bacteria,2GKNW@201174|Actinobacteria	201174|Actinobacteria	P	alcohol dehydrogenase	-	-	-	ko:K18382	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_4204882_10	869210.Marky_1921	5.52e-23	104.0	COG0517@1|root,COG5485@1|root,COG0517@2|Bacteria,COG5485@2|Bacteria,1WK3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRD3_k127_4204882_3	1122609.AUGT01000030_gene2543	1.676e-131	454.0	COG2909@1|root,COG3899@1|root,COG2909@2|Bacteria,COG3899@2|Bacteria,2GM1B@201174|Actinobacteria,4DTFJ@85009|Propionibacteriales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE,Trans_reg_C
SRD3_k127_4207892_2	1380355.JNIJ01000016_gene5716	5.214e-22	96.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2TUKR@28211|Alphaproteobacteria,3JRSS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
SRD3_k127_4207892_3	266940.Krad_1844	1.892e-08	62.0	2C3UR@1|root,330BB@2|Bacteria,2GU03@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4207892_0	471852.Tcur_3035	2.543e-106	353.0	COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria,4EGR2@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
SRD3_k127_4207892_1	235985.BBPN01000041_gene267	1.788e-37	143.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria,2NFQW@228398|Streptacidiphilus	201174|Actinobacteria	E	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
SRD3_k127_4230961_6	1157637.KB892091_gene5518	1.92e-33	148.0	COG1520@1|root,COG3420@1|root,COG1520@2|Bacteria,COG3420@2|Bacteria,2IAZ2@201174|Actinobacteria	201174|Actinobacteria	KLT	PQQ enzyme repeat	-	-	1.1.2.6,2.7.11.1	ko:K05889,ko:K12132	-	-	R03136	-	ko00000,ko01000,ko01001	-	-	-	PQQ,PQQ_2,PQQ_3,Pkinase
SRD3_k127_4230961_4	1056816.JAFQ01000004_gene317	2.521e-58	213.0	COG1946@1|root,COG1946@2|Bacteria	2|Bacteria	I	acyl-CoA hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRD3_k127_4230961_3	1068980.ARVW01000001_gene6015	5.774e-74	276.0	COG0406@1|root,COG0406@2|Bacteria,2HUBQ@201174|Actinobacteria,4E141@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRD3_k127_4230961_7	448385.sce0137	6.534e-23	113.0	arCOG07238@1|root,34BTI@2|Bacteria,1P13S@1224|Proteobacteria,4354M@68525|delta/epsilon subdivisions,2WZFN@28221|Deltaproteobacteria,2Z21A@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4230961_8	1132441.KI519454_gene28	1.505e-19	100.0	COG3662@1|root,COG3662@2|Bacteria,2GNTU@201174|Actinobacteria,1W90H@1268|Micrococcaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRD3_k127_4230961_0	402881.Plav_0222	4.353e-94	316.0	COG1024@1|root,COG1024@2|Bacteria,1RA5T@1224|Proteobacteria,2UP3E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD3_k127_4230961_5	1282876.BAOK01000001_gene3434	1.38e-38	150.0	COG1917@1|root,COG1917@2|Bacteria,1RB86@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Cupin 2 conserved barrel domain protein	-	-	1.13.11.41	ko:K05913	ko00363,ko01120,map00363,map01120	-	R01305	RC00415,RC01565	ko00000,ko00001,ko01000	-	-	-	Cupin_7
SRD3_k127_4230961_2	1408452.JAGZ01000001_gene3751	4.949e-92	321.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,235I4@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRD3_k127_4230961_1	1123024.AUII01000012_gene4103	1.687e-93	310.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4E0PU@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_4234239_10	543632.JOJL01000019_gene10171	1.567e-18	96.0	COG4188@1|root,COG4188@2|Bacteria,2I9HM@201174|Actinobacteria,4D9BG@85008|Micromonosporales	201174|Actinobacteria	S	Chlorophyllase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2,PAF-AH_p_II
SRD3_k127_4234239_4	1157638.KB892158_gene5318	4.308e-58	205.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria	201174|Actinobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRD3_k127_4234239_7	351607.Acel_2092	5.898e-38	156.0	COG3786@1|root,COG3786@2|Bacteria,2GNX8@201174|Actinobacteria,4ETA4@85013|Frankiales	201174|Actinobacteria	D	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRD3_k127_4234239_6	58123.JOFJ01000011_gene4696	2.252e-55	202.0	COG2843@1|root,COG2843@2|Bacteria,2GP72@201174|Actinobacteria,4EFP1@85012|Streptosporangiales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRD3_k127_4234239_2	1267533.KB906738_gene2164	2.641e-99	337.0	COG0258@1|root,COG0258@2|Bacteria,3Y2FG@57723|Acidobacteria,2JME1@204432|Acidobacteriia	204432|Acidobacteriia	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRD3_k127_4234239_3	1380390.JIAT01000012_gene2922	9.152e-98	336.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4CT0K@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
SRD3_k127_4234239_8	1313172.YM304_28130	3.637e-30	123.0	COG1545@1|root,COG1545@2|Bacteria,2IFHZ@201174|Actinobacteria	201174|Actinobacteria	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
SRD3_k127_4234239_9	1267534.KB906758_gene2324	1.145e-20	106.0	COG5424@1|root,COG5424@2|Bacteria	2|Bacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	CP_1111	GO:0005575,GO:0005576	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2,TENA_THI-4
SRD3_k127_4234239_5	479432.Sros_3100	1.328e-57	222.0	COG2808@1|root,COG2808@2|Bacteria,2I9QJ@201174|Actinobacteria,4EJ9I@85012|Streptosporangiales	201174|Actinobacteria	K	Putative FMN-binding domain	paiB	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
SRD3_k127_4234239_0	710685.MycrhN_4733	1.868e-152	507.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRD3_k127_4234239_1	557599.MKAN_03160	9.36e-112	372.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,237H5@1762|Mycobacteriaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_4234887_0	1122138.AQUZ01000003_gene580	2.636e-138	449.0	COG1132@1|root,COG1132@2|Bacteria,2GJYK@201174|Actinobacteria,4DT7S@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRD3_k127_4234887_1	1122138.AQUZ01000003_gene579	4.268e-69	237.0	COG1132@1|root,COG1132@2|Bacteria,2GJYK@201174|Actinobacteria,4DTSS@85009|Propionibacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRD3_k127_423988_0	1229780.BN381_640016	1.021e-137	452.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	bglIM	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRD3_k127_4262937_0	469383.Cwoe_2658	2.206e-140	451.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CP7J@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRD3_k127_4262937_1	1121877.JQKF01000001_gene1383	1.314e-47	181.0	COG1792@1|root,COG1792@2|Bacteria,2HGG4@201174|Actinobacteria,4CNDF@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRD3_k127_4262937_2	28444.JODQ01000007_gene6079	3.75e-05	54.0	COG2891@1|root,COG2891@2|Bacteria,2GN0I@201174|Actinobacteria,4EKPH@85012|Streptosporangiales	201174|Actinobacteria	M	rod shape-determining protein (MreD)	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
SRD3_k127_4273075_0	1313172.YM304_16500	3.553e-95	319.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CMWG@84992|Acidimicrobiia	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	rimO	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
SRD3_k127_4273075_1	1125971.ASJB01000065_gene6212	2.458e-24	117.0	COG0477@1|root,COG2814@2|Bacteria,2HCHA@201174|Actinobacteria,4E1VJ@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2
SRD3_k127_4295242_3	1313172.YM304_25010	2.227e-26	124.0	COG0560@1|root,COG0560@2|Bacteria,2GTHF@201174|Actinobacteria	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.27	ko:K18697	ko00564,map00564	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD
SRD3_k127_4295242_1	337191.KTR9_2355	9.002e-93	325.0	COG1024@1|root,COG1024@2|Bacteria,2GJ63@201174|Actinobacteria,4GCN8@85026|Gordoniaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD3_k127_4295242_0	391625.PPSIR1_20549	1.928e-99	343.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,42Q1Z@68525|delta/epsilon subdivisions,2WM01@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRD3_k127_4295242_5	58123.JOFJ01000005_gene1348	6.595e-10	72.0	2EG6R@1|root,339YM@2|Bacteria,2GU6A@201174|Actinobacteria,4EKF7@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707
SRD3_k127_4295242_4	1137271.AZUM01000004_gene3959	2.32e-13	76.0	COG1983@1|root,COG1983@2|Bacteria,2GIVS@201174|Actinobacteria,4E1BF@85010|Pseudonocardiales	201174|Actinobacteria	KT	PFAM PspC domain	pspC	-	-	-	-	-	-	-	-	-	-	-	DUF2154,PspC
SRD3_k127_4295242_2	1445613.JALM01000018_gene5777	1.266e-74	271.0	COG4585@1|root,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4DXQC@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	tcsS3	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,PspC
SRD3_k127_4338258_0	525909.Afer_1575	3.049e-116	387.0	COG4213@1|root,COG4213@2|Bacteria,2GKRE@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter substrate-binding protein	xylF	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
SRD3_k127_4338258_1	1157632.AQWQ01000003_gene2083	2.825e-39	156.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRD3_k127_4338309_3	1089545.KB913037_gene7139	1.272e-10	72.0	COG0640@1|root,COG0640@2|Bacteria,2IR66@201174|Actinobacteria,4E6K9@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRD3_k127_4338309_0	35754.JNYJ01000003_gene6464	2.056e-180	579.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4D9EC@85008|Micromonosporales	201174|Actinobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRD3_k127_4338309_2	1380356.JNIK01000004_gene24	2.766e-107	356.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria,4ERND@85013|Frankiales	201174|Actinobacteria	S	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine	egtD	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008213,GO:0008276,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0019439,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0036211,GO:0042398,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052707,GO:0052708,GO:0052709,GO:0052803,GO:0052805,GO:0071704,GO:0071944,GO:0097164,GO:0140096,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
SRD3_k127_4338309_1	450851.PHZ_c1906	2.359e-160	515.0	COG1262@1|root,COG4301@1|root,COG1262@2|Bacteria,COG4301@2|Bacteria,1MUNC@1224|Proteobacteria,2TQXE@28211|Alphaproteobacteria,2KFXT@204458|Caulobacterales	204458|Caulobacterales	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_33
SRD3_k127_4349890_0	1121877.JQKF01000003_gene1581	5.761e-74	251.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4CMYS@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRD3_k127_4349890_1	525909.Afer_0488	1.148e-29	121.0	COG2331@1|root,COG2331@2|Bacteria,2HGEB@201174|Actinobacteria,4CP29@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4352436_1	43354.JOIJ01000002_gene4431	1.319e-153	493.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4DX83@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase	ligC	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRD3_k127_4352436_3	1048339.KB913029_gene2088	3.217e-22	107.0	COG0642@1|root,COG2172@1|root,COG2203@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria,4EXCE@85013|Frankiales	201174|Actinobacteria	T	Sigma factor PP2C-like phosphatases	rsbU	GO:0000287,GO:0003674,GO:0003824,GO:0004035,GO:0005488,GO:0005515,GO:0006355,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019219,GO:0019222,GO:0030145,GO:0031323,GO:0031326,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c_2,PAS_4,STAS,STAS_2,SpoIIE
SRD3_k127_4352436_0	675635.Psed_6030	1.354e-195	640.0	COG3387@1|root,COG3387@2|Bacteria,2GMF8@201174|Actinobacteria,4E0ZJ@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRD3_k127_4352436_2	1003195.SCAT_5034	4.467e-59	217.0	COG0697@1|root,COG0697@2|Bacteria,2GRXH@201174|Actinobacteria	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4366837_4	391037.Sare_1542	7.454e-30	125.0	COG1576@1|root,COG1576@2|Bacteria,2IGAN@201174|Actinobacteria,4DFNX@85008|Micromonosporales	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRD3_k127_4366837_2	1229780.BN381_20046	1.008e-57	205.0	2CG3W@1|root,32X0W@2|Bacteria,2GUB9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4366837_0	1048339.KB913029_gene1970	2.486e-138	444.0	COG1024@1|root,COG1024@2|Bacteria,2GN3P@201174|Actinobacteria,4EVPG@85013|Frankiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA4	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD3_k127_4366837_3	2074.JNYD01000003_gene3626	4.116e-35	150.0	2E2XX@1|root,32XYT@2|Bacteria,2IK9M@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4366837_1	1173026.Glo7428_0163	4.389e-137	442.0	COG3733@1|root,COG3733@2|Bacteria,1G2YB@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM copper amine oxidase	-	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
SRD3_k127_438347_7	1307761.L21SP2_3206	3.834e-05	49.0	COG0438@1|root,COG0438@2|Bacteria,2J6VH@203691|Spirochaetes	203691|Spirochaetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRD3_k127_438347_2	1313172.YM304_09550	6.674e-43	166.0	COG1309@1|root,COG1309@2|Bacteria,2HGBF@201174|Actinobacteria,4CNA8@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD3_k127_438347_1	446470.Snas_5222	4.191e-52	190.0	2DMC7@1|root,32J0V@2|Bacteria,2I81N@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
SRD3_k127_438347_5	1123320.KB889689_gene500	4.946e-25	116.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ywlE	-	2.7.7.87,3.1.3.48,3.9.1.2,5.3.1.6	ko:K01104,ko:K01808,ko:K07566,ko:K20201	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030,R10463	RC00376,RC00434,RC00745	ko00000,ko00001,ko00002,ko01000,ko03009,ko03016	-	-	-	LMWPc
SRD3_k127_438347_3	40571.JOEA01000030_gene5596	9.53e-42	158.0	COG0454@1|root,COG0456@2|Bacteria,2IJC7@201174|Actinobacteria,4E5XB@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD3_k127_438347_4	797209.ZOD2009_16493	3.072e-30	130.0	COG3332@1|root,arCOG06429@2157|Archaea,2XU65@28890|Euryarchaeota,23UCP@183963|Halobacteria	183963|Halobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
SRD3_k127_438347_6	1121877.JQKF01000072_gene2093	1.21e-18	91.0	2EG9A@1|root,33A12@2|Bacteria,2GQ7U@201174|Actinobacteria,4CNB5@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_438347_0	1121877.JQKF01000016_gene124	2.11e-198	625.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4CMRQ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_4390614_1	1463895.JODA01000057_gene4092	8.493e-79	273.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA11	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRD3_k127_4390614_2	47839.CCAU010000009_gene1721	2.1e-38	148.0	COG1545@1|root,COG1545@2|Bacteria,2IH6P@201174|Actinobacteria,23998@1762|Mycobacteriaceae	201174|Actinobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	OB_aCoA_assoc
SRD3_k127_4390614_0	1386969.AWTB01000100_gene3497	2.625e-183	581.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4GB15@85026|Gordoniaceae	201174|Actinobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
SRD3_k127_4390614_3	1122614.JHZF01000016_gene411	2.162e-12	73.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VFYM@28211|Alphaproteobacteria,2PF9G@252301|Oceanicola	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRD3_k127_4423279_2	1229780.BN381_290088	4.091e-92	316.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,3UWCU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
SRD3_k127_4423279_0	1313172.YM304_24900	7.332e-254	801.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CMQD@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRD3_k127_4423279_11	1313172.YM304_24910	3.395e-37	151.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,4CNBA@84992|Acidimicrobiia	84992|Acidimicrobiia	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRD3_k127_4423279_5	1313172.YM304_24920	6.101e-88	304.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CMZU@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRD3_k127_4423279_12	713586.KB900536_gene1877	1.907e-16	83.0	COG1734@1|root,COG1734@2|Bacteria,1N8K6@1224|Proteobacteria,1SCNZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	DnaK suppressor protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRD3_k127_4423279_9	525909.Afer_1132	1.39e-49	190.0	COG1994@1|root,COG1994@2|Bacteria,2GM8E@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase M50	rip2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRD3_k127_4423279_1	1003195.SCAT_2599	5.693e-107	372.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRD3_k127_4423279_7	1229780.BN381_290072	1.519e-57	223.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,3UWJ9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRD3_k127_4423279_8	1313172.YM304_24970	2.141e-56	205.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4CN9J@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRD3_k127_4423279_6	1229780.BN381_290070	1.55e-87	301.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,3UWKC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	RNA pseudouridylate synthase	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRD3_k127_4423279_10	525909.Afer_1355	1.445e-42	158.0	COG4401@1|root,COG4401@2|Bacteria,2IHWT@201174|Actinobacteria,4CNUX@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Chorismate mutase type I	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
SRD3_k127_4423279_3	1313172.YM304_24990	3.063e-90	317.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CNBS@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRD3_k127_4423279_4	1122970.AUHC01000001_gene729	2.488e-88	306.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2TR6W@28211|Alphaproteobacteria,2K0WH@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRD3_k127_4430575_3	28042.GU90_09085	4.534e-15	79.0	COG2227@1|root,COG2227@2|Bacteria,2H217@201174|Actinobacteria	201174|Actinobacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4430575_1	1246995.AFR_04305	5.383e-64	246.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4430575_0	543632.JOJL01000036_gene3013	1.036e-82	302.0	COG1520@1|root,COG1520@2|Bacteria,2I9FJ@201174|Actinobacteria	201174|Actinobacteria	M	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRD3_k127_4430575_2	1123320.KB889700_gene9200	4.421e-26	108.0	COG3467@1|root,COG3467@2|Bacteria,2IFJS@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRD3_k127_4448320_0	1048339.KB913029_gene4160	2.96e-80	278.0	COG0730@1|root,COG0730@2|Bacteria,2GNW8@201174|Actinobacteria,4ESDT@85013|Frankiales	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRD3_k127_4448320_3	1120934.KB894432_gene6167	1.389e-14	80.0	COG1582@1|root,COG1582@2|Bacteria,2GRTC@201174|Actinobacteria,4EDIN@85010|Pseudonocardiales	201174|Actinobacteria	N	Flagellar protein (FlbD)	flbD	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
SRD3_k127_4448320_1	1169152.AXVD01000013_gene1691	1.247e-40	156.0	COG0748@1|root,COG0748@2|Bacteria,2IP0W@201174|Actinobacteria,4G0RC@85025|Nocardiaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRD3_k127_4448320_2	263358.VAB18032_27071	9.88e-38	150.0	COG1040@1|root,COG2114@1|root,COG3899@1|root,COG1040@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRD3_k127_4472180_12	543632.JOJL01000002_gene8158	1.426e-35	156.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,4DANW@85008|Micromonosporales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD3_k127_4472180_2	1229780.BN381_430065	1.607e-203	654.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,3UWA8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRD3_k127_4472180_14	525909.Afer_1632	0.0007463	53.0	2ANCX@1|root,31DBG@2|Bacteria,2HGYA@201174|Actinobacteria,4CNYJ@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4472180_0	1121877.JQKF01000027_gene2474	0.0	1543.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CMWT@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DNA polymerase alpha chain like domain	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRD3_k127_4472180_10	1123024.AUII01000002_gene1004	7.841e-50	189.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria,4E2RM@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2587)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2587
SRD3_k127_4472180_3	1229780.BN381_430074	9.383e-119	393.0	COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,3UWWP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRD3_k127_4472180_7	1313172.YM304_19590	9.473e-67	229.0	COG1959@1|root,COG1959@2|Bacteria,2HG5V@201174|Actinobacteria,4CN2Q@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRD3_k127_4472180_4	105420.BBPO01000001_gene221	3.307e-100	342.0	2DBVK@1|root,2ZBBH@2|Bacteria,2H5Z5@201174|Actinobacteria,2NEQI@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4472180_8	1463856.JOHY01000053_gene7442	3.575e-57	219.0	COG0406@1|root,COG0406@2|Bacteria,2GNRS@201174|Actinobacteria	201174|Actinobacteria	G	Phosphoglycerate mutase	-	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRD3_k127_4472180_5	525909.Afer_1208	7.675e-85	308.0	COG0568@1|root,COG0568@2|Bacteria,2H445@201174|Actinobacteria,4CNJ9@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD3_k127_4472180_6	1313172.YM304_19580	9.714e-74	262.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CN1X@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
SRD3_k127_4472180_13	1121877.JQKF01000014_gene13	2.117e-26	117.0	COG0597@1|root,COG0597@2|Bacteria,2HGGT@201174|Actinobacteria,4CNE4@84992|Acidimicrobiia	84992|Acidimicrobiia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRD3_k127_4472180_11	1121877.JQKF01000014_gene14	1.169e-36	151.0	COG1734@1|root,COG1734@2|Bacteria,2HH4M@201174|Actinobacteria,4CP4R@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4472180_1	263358.VAB18032_28546	0.0	1111.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4D973@85008|Micromonosporales	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRD3_k127_4474287_0	1229780.BN381_330056	1.524e-137	448.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,3UWAE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2870c	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRD3_k127_4474287_5	1121877.JQKF01000004_gene1131	2.52e-53	211.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,4CN3S@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRD3_k127_4474287_4	1313172.YM304_27460	1.292e-53	205.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4CN2Z@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRD3_k127_4474287_2	1229780.BN381_330053	3.174e-92	310.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,3UW78@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRD3_k127_4474287_3	1313172.YM304_27480	1.384e-89	302.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CMXN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRD3_k127_4474287_1	1229780.BN381_330051	1.798e-102	342.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,3UWBA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRD3_k127_4474287_6	1306174.JODP01000016_gene7134	7.46e-21	94.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	whiG	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD3_k127_4477065_2	953739.SVEN_7148	5.263e-26	118.0	COG1309@1|root,COG1309@2|Bacteria,2IEU9@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD3_k127_4477065_0	1313172.YM304_12950	2.617e-134	444.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CMRN@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
SRD3_k127_4477065_1	1370120.AUWR01000011_gene1092	3.346e-61	225.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,235GY@1762|Mycobacteriaceae	201174|Actinobacteria	C	NADPH quinone	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_4478572_4	1056816.JAFQ01000004_gene961	1.815e-07	60.0	2EQSP@1|root,33ICH@2|Bacteria,2GWX9@201174|Actinobacteria,4G2K3@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4478572_0	298654.FraEuI1c_6541	9.713e-270	839.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria,4ET01@85013|Frankiales	201174|Actinobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3
SRD3_k127_4478572_2	1265310.CCBD010000070_gene38	4.955e-60	224.0	COG2267@1|root,COG2267@2|Bacteria,2I5VQ@201174|Actinobacteria	201174|Actinobacteria	I	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
SRD3_k127_4478572_3	66429.JOFL01000006_gene1864	1.604e-56	210.0	2DMBY@1|root,32ICA@2|Bacteria,2IFRZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4478572_1	1123322.KB904680_gene3355	7.045e-76	258.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria	201174|Actinobacteria	M	mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SRD3_k127_4485720_0	1283299.AUKG01000001_gene2978	3.438e-72	258.0	COG0438@1|root,COG0438@2|Bacteria,2IFGX@201174|Actinobacteria,4CSNE@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRD3_k127_4485720_2	298654.FraEuI1c_2459	1.457e-45	177.0	COG0457@1|root,COG0457@2|Bacteria	298654.FraEuI1c_2459|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4485720_3	700508.D174_13090	4.149e-36	150.0	COG1216@1|root,COG1216@2|Bacteria,2GKTW@201174|Actinobacteria,236PP@1762|Mycobacteriaceae	201174|Actinobacteria	S	glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_7C,Glycos_transf_2
SRD3_k127_4485720_1	929712.KI912613_gene4902	2.634e-50	199.0	COG1216@1|root,COG1216@2|Bacteria,2HFEQ@201174|Actinobacteria,4CT5B@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD3_k127_4491051_0	1229780.BN381_20106	1.565e-292	912.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,3UW8A@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRD3_k127_4491051_1	525909.Afer_1593	2.032e-05	55.0	COG0760@1|root,COG0760@2|Bacteria,2HGN4@201174|Actinobacteria,4CNNU@84992|Acidimicrobiia	84992|Acidimicrobiia	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	-
SRD3_k127_4502361_2	2002.JOEQ01000003_gene2374	3.927e-70	240.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4EHPJ@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_4502361_4	543632.JOJL01000027_gene2599	1.187e-53	201.0	COG2030@1|root,COG2030@2|Bacteria,2GIXP@201174|Actinobacteria,4DE8G@85008|Micromonosporales	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRD3_k127_4502361_3	1229780.BN381_450029	1.387e-63	228.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,3UWS5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRD3_k127_4502361_0	1313172.YM304_22590	1.457e-91	310.0	COG0454@1|root,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,4CN0X@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	-	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRD3_k127_4502361_1	525909.Afer_1461	1.253e-70	246.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4CN7C@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRD3_k127_4502583_0	479434.Sthe_3075	3.161e-40	174.0	COG0642@1|root,COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
SRD3_k127_4502583_1	1131812.JQMS01000001_gene1798	4.516e-08	66.0	COG3291@1|root,COG3291@2|Bacteria,4P5PB@976|Bacteroidetes,1IKQ7@117743|Flavobacteriia,2NSJH@237|Flavobacterium	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4502946_1	1313172.YM304_10900	6.977e-76	265.0	COG0312@1|root,COG0312@2|Bacteria,2HGNU@201174|Actinobacteria,4CNQT@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRD3_k127_4502946_0	1229780.BN381_90073	1.102e-193	614.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,3UXHF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRD3_k127_4507904_8	471852.Tcur_3385	2.137e-49	184.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4EMUX@85012|Streptosporangiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD3_k127_4507904_4	1003195.SCAT_5382	8.222e-87	326.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase M24B family	pepE	-	3.4.13.9	ko:K01271,ko:K01274	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRD3_k127_4507904_2	1313172.YM304_29640	6.054e-181	582.0	COG0320@1|root,COG0321@1|root,COG0320@2|Bacteria,COG0321@2|Bacteria,2GKD4@201174|Actinobacteria,4CMR4@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,LIAS_N,Radical_SAM
SRD3_k127_4507904_3	1121877.JQKF01000001_gene1338	4.075e-138	456.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4CMW0@84992|Acidimicrobiia	84992|Acidimicrobiia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRD3_k127_4507904_1	1229780.BN381_210107	1.396e-190	605.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,3UWCV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRD3_k127_4507904_9	2002.JOEQ01000049_gene2224	2.768e-13	75.0	COG4911@1|root,COG4911@2|Bacteria,2IMEK@201174|Actinobacteria,4EJXV@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRD3_k127_4507904_5	526225.Gobs_4316	1.019e-83	285.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,4EU5K@85013|Frankiales	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRD3_k127_4507904_7	397278.JOJN01000002_gene644	2.104e-54	199.0	COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,4DR5Z@85009|Propionibacteriales	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF4440,RNase_H
SRD3_k127_4507904_0	469371.Tbis_2360	0.0	1140.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria,4DXNT@85010|Pseudonocardiales	201174|Actinobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRD3_k127_4507904_6	1122603.ATVI01000006_gene304	2.231e-83	293.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase S15	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
SRD3_k127_4517414_4	1449346.JQMO01000002_gene882	0.0003039	53.0	2FB55@1|root,343BG@2|Bacteria,2IKSK@201174|Actinobacteria,2M55Z@2063|Kitasatospora	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4517414_0	1429046.RR21198_1108	6.553e-91	318.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4FV5H@85025|Nocardiaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_4517414_2	1463921.JODF01000158_gene4211	2.823e-54	194.0	COG1545@1|root,COG1545@2|Bacteria,2II25@201174|Actinobacteria	201174|Actinobacteria	EGP	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRD3_k127_4517414_1	58123.JOFJ01000014_gene4980	1.77e-82	289.0	COG1028@1|root,COG1028@2|Bacteria,2IEID@201174|Actinobacteria	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD3_k127_4517414_3	570268.ANBB01000047_gene3998	1.179e-16	81.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRD3_k127_4534549_1	2002.JOEQ01000005_gene3373	2.304e-57	220.0	28KAT@1|root,2Z9XX@2|Bacteria,2GNVW@201174|Actinobacteria,4ENJ3@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4534549_0	298655.KI912266_gene542	5.266e-153	496.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	1.14.13.221	ko:K16046	ko00984,ko01120,map00984,map01120	-	R09859,R11361	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRD3_k127_4534549_2	471852.Tcur_2587	1.321e-28	120.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria,4EGMR@85012|Streptosporangiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD3_k127_4537767_1	1122182.KB903813_gene2792	5.641e-22	106.0	COG0463@1|root,COG2244@1|root,COG0463@2|Bacteria,COG2244@2|Bacteria,2I7M5@201174|Actinobacteria,4DFBM@85008|Micromonosporales	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Polysacc_synt_3
SRD3_k127_4537767_0	35754.JNYJ01000058_gene8629	4.299e-47	173.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4DCDN@85008|Micromonosporales	201174|Actinobacteria	P	Ammonium Transporter Family	amt_1	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRD3_k127_4575773_2	1246995.AFR_04305	2.191e-73	266.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4575773_0	1382306.JNIM01000001_gene736	2.708e-173	563.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,2G83U@200795|Chloroflexi	200795|Chloroflexi	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Voltage_CLC
SRD3_k127_4575773_1	1229780.BN381_10328	6.238e-78	264.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,3UX6E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRD3_k127_4596881_0	710696.Intca_1398	1.814e-272	846.0	COG0422@1|root,COG0422@2|Bacteria,2GJ3Y@201174|Actinobacteria,4FG52@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
SRD3_k127_4596881_1	1229780.BN381_80340	7.838e-140	460.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,3UW8N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRD3_k127_4596881_2	215803.DB30_4708	2.463e-12	79.0	COG0388@1|root,COG0388@2|Bacteria,1Q1Q0@1224|Proteobacteria,439D4@68525|delta/epsilon subdivisions,2X4MT@28221|Deltaproteobacteria,2YZ9K@29|Myxococcales	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRD3_k127_4597258_2	1121877.JQKF01000001_gene1362	7.855e-07	53.0	COG0438@1|root,COG0438@2|Bacteria,2GMEW@201174|Actinobacteria,4CNQH@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD3_k127_4597258_1	65497.JODV01000013_gene2264	2.046e-58	220.0	COG0438@1|root,COG0438@2|Bacteria,2GK9J@201174|Actinobacteria,4DX75@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRD3_k127_4597258_0	1229780.BN381_10190	9.109e-88	317.0	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRD3_k127_4617830_2	1173028.ANKO01000112_gene4816	5.313e-31	122.0	COG0235@1|root,COG0235@2|Bacteria,1G10W@1117|Cyanobacteria,1H8SZ@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SRD3_k127_4617830_0	285535.JOEY01000075_gene5963	2.826e-163	526.0	COG2141@1|root,COG2141@2|Bacteria,2GITK@201174|Actinobacteria	201174|Actinobacteria	C	Monooxygenase	limB	-	1.14.13.107	ko:K14733	ko00903,map00903	-	R06398,R09385,R09389,R09393	RC01506	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRD3_k127_4617830_3	436229.JOEH01000014_gene6138	1.326e-16	93.0	2B61P@1|root,31K2V@2|Bacteria,2HP2D@201174|Actinobacteria,2NJE6@228398|Streptacidiphilus	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRD3_k127_4617830_1	1121877.JQKF01000002_gene1720	2.508e-142	460.0	COG1003@1|root,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4CMXT@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Glycine cleavage system P-protein	-	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRD3_k127_4622478_1	1463857.JOFZ01000008_gene525	6.73e-43	162.0	COG2021@1|root,COG2021@2|Bacteria,2I5C3@201174|Actinobacteria	201174|Actinobacteria	E	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRD3_k127_4622478_0	390989.JOEG01000014_gene3086	1.33e-88	302.0	COG3173@1|root,COG3173@2|Bacteria,2GKUU@201174|Actinobacteria,4DD6T@85008|Micromonosporales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRD3_k127_4622478_2	1157632.AQWQ01000001_gene5289	4.237e-39	154.0	2CH5R@1|root,32S5B@2|Bacteria,2IQUR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRD3_k127_4622478_3	1449976.KALB_1266	5.823e-05	51.0	COG3427@1|root,COG3427@2|Bacteria,2I5DX@201174|Actinobacteria,4EDWB@85010|Pseudonocardiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRD3_k127_4631463_1	1313172.YM304_37950	1.743e-42	168.0	COG2365@1|root,COG2365@2|Bacteria,2GK28@201174|Actinobacteria,4CNVE@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
SRD3_k127_4631463_2	1894.JOER01000003_gene2832	1.116e-14	83.0	29CFH@1|root,2ZZDX@2|Bacteria,2IN9J@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4631463_0	105425.BBPL01000040_gene3453	8.304e-140	464.0	COG4412@1|root,COG4934@1|root,COG4412@2|Bacteria,COG4934@2|Bacteria,2I8QH@201174|Actinobacteria,2NHSW@228398|Streptacidiphilus	201174|Actinobacteria	O	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
SRD3_k127_4657102_0	477641.MODMU_4459	1.491e-233	746.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4ERTG@85013|Frankiales	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRD3_k127_4657102_1	525909.Afer_1003	3.025e-129	427.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4CMWK@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cell cycle protein	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
SRD3_k127_4657102_4	1033730.CAHG01000014_gene1750	1.571e-12	81.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4DQGH@85009|Propionibacteriales	201174|Actinobacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRD3_k127_4657102_2	525909.Afer_0956	3.448e-95	337.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,4CN2U@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cell cycle protein	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRD3_k127_4657102_3	58123.JOFJ01000012_gene5329	7.937e-43	179.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria,4EHI0@85012|Streptosporangiales	201174|Actinobacteria	M	Mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRD3_k127_4657520_1	1121946.AUAX01000029_gene1996	2.998e-14	84.0	COG0463@1|root,COG2244@1|root,COG0463@2|Bacteria,COG2244@2|Bacteria,2I7M5@201174|Actinobacteria,4DFBM@85008|Micromonosporales	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Polysacc_synt_3
SRD3_k127_4657520_2	1123320.KB889627_gene7913	3.164e-05	55.0	2BEUS@1|root,328KD@2|Bacteria,2HEDT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4657520_0	1123023.JIAI01000006_gene273	2.428e-143	469.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4DX4Q@85010|Pseudonocardiales	201174|Actinobacteria	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRD3_k127_4680553_7	1297570.MESS4_750310	1.61e-19	102.0	COG0500@1|root,COG2226@2|Bacteria,1N5QH@1224|Proteobacteria,2UM5M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
SRD3_k127_4680553_3	1121877.JQKF01000006_gene940	1.012e-84	293.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria	201174|Actinobacteria	J	Phenazine biosynthesis protein PhzF	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRD3_k127_4680553_5	247156.NFA_41920	4.269e-29	122.0	COG4308@1|root,COG4308@2|Bacteria,2IP4X@201174|Actinobacteria,4G2E2@85025|Nocardiaceae	201174|Actinobacteria	Q	Limonene-1,2-epoxide hydrolase catalytic domain	-	-	3.3.2.8	ko:K10533	ko00903,map00903	-	R05784,R09387	RC01473,RC02519	ko00000,ko00001,ko01000	-	-	-	LEH
SRD3_k127_4680553_4	1380356.JNIK01000011_gene1767	2.362e-43	162.0	COG0517@1|root,COG0517@2|Bacteria,2IHPB@201174|Actinobacteria,4ET4E@85013|Frankiales	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRD3_k127_4680553_2	247156.NFA_48000	1.922e-131	439.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4FVQ5@85025|Nocardiaceae	201174|Actinobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRD3_k127_4680553_0	1313172.YM304_16690	2.305e-245	768.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4CMUP@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRD3_k127_4680553_1	1313172.YM304_10760	3.001e-144	470.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CMR2@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRD3_k127_4680553_6	1463821.JOGR01000003_gene863	4.238e-22	99.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4EXK0@85014|Glycomycetales	201174|Actinobacteria	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRD3_k127_4695662_0	1229780.BN381_130019	1.629e-133	439.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,3UWF7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRD3_k127_4695662_1	643562.Daes_3193	3.484e-38	158.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,42N9R@68525|delta/epsilon subdivisions,2WN5P@28221|Deltaproteobacteria,2M85C@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	SMART phosphoesterase PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
SRD3_k127_4736254_1	926550.CLDAP_06320	1.327e-29	119.0	COG0667@1|root,COG0667@2|Bacteria,2G5YU@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRD3_k127_4736254_0	1313172.YM304_17270	6.599e-82	288.0	COG0477@1|root,COG2814@2|Bacteria,2I2IS@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRD3_k127_4736528_0	1150599.MPHLEI_18750	3.746e-186	586.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,232CR@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_4736528_1	1463861.JNXE01000017_gene7655	3.84e-117	396.0	COG3173@1|root,COG3173@2|Bacteria,2GJ58@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRD3_k127_4750213_8	1348663.KCH_75120	3.862e-13	74.0	COG5592@1|root,COG5592@2|Bacteria,2IGW0@201174|Actinobacteria,2M3GZ@2063|Kitasatospora	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRD3_k127_4750213_7	1476876.JOJO01000045_gene1292	1.631e-24	114.0	COG5592@1|root,COG5592@2|Bacteria,2HF5Y@201174|Actinobacteria	201174|Actinobacteria	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRD3_k127_4750213_5	105425.BBPL01000013_gene1793	2.647e-44	166.0	COG4420@1|root,COG4420@2|Bacteria,2ID70@201174|Actinobacteria,2NK91@228398|Streptacidiphilus	201174|Actinobacteria	T	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
SRD3_k127_4750213_0	1229780.BN381_250088	2.059e-147	484.0	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the long-chain O-acyltransferase family	-	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRD3_k127_4750213_3	1120936.KB907220_gene1988	3.433e-100	342.0	COG0657@1|root,COG0657@2|Bacteria,2GTEV@201174|Actinobacteria,4EPWP@85012|Streptosporangiales	201174|Actinobacteria	I	Carboxylesterase family	lipM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRD3_k127_4750213_6	1121272.KB903292_gene3948	2.111e-37	157.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRD3_k127_4750213_2	1121272.KB903292_gene3947	2.596e-119	405.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4DJIF@85008|Micromonosporales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRD3_k127_4750213_4	1120983.KB894570_gene1841	1.382e-90	319.0	COG1129@1|root,COG4177@1|root,COG1129@2|Bacteria,COG4177@2|Bacteria,1R9IW@1224|Proteobacteria,2TWGB@28211|Alphaproteobacteria,1JPVT@119043|Rhodobiaceae	28211|Alphaproteobacteria	EG	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRD3_k127_4750213_1	1123320.KB889697_gene8996	4.521e-129	420.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRD3_k127_4772315_1	483219.LILAB_00970	3.933e-51	192.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,42USD@68525|delta/epsilon subdivisions,2WQCM@28221|Deltaproteobacteria,2YXGM@29|Myxococcales	28221|Deltaproteobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRD3_k127_4772315_0	530564.Psta_4360	2.441e-121	400.0	COG2141@1|root,COG2141@2|Bacteria,2J00I@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_4796894_3	1048339.KB913029_gene3130	1.606e-85	291.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4ESZE@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_4796894_4	876044.IMCC3088_132	6.196e-79	280.0	2DBBP@1|root,2Z88Z@2|Bacteria,1R3B4@1224|Proteobacteria,1S25X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRD3_k127_4796894_5	264198.Reut_A1532	4.27e-58	218.0	COG5361@1|root,COG5361@2|Bacteria,1PF7H@1224|Proteobacteria,2VK8N@28216|Betaproteobacteria,1K5DE@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
SRD3_k127_4796894_2	164757.Mjls_3741	7.948e-109	365.0	COG0451@1|root,COG0451@2|Bacteria,2I9DG@201174|Actinobacteria,237C3@1762|Mycobacteriaceae	201174|Actinobacteria	GM	NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRD3_k127_4796894_1	266117.Rxyl_0492	2.045e-123	428.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CRHY@84995|Rubrobacteria	84995|Rubrobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4
SRD3_k127_4796894_0	525904.Tter_2662	9.652e-151	490.0	COG2267@1|root,COG2267@2|Bacteria,2NRKH@2323|unclassified Bacteria	2|Bacteria	I	Alpha/beta hydrolase family	fpaP	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRD3_k127_4796894_6	357808.RoseRS_0952	4.351e-38	149.0	COG2605@1|root,COG2605@2|Bacteria	2|Bacteria	G	GHMP kinase	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,GHMP_kinases_C,GHMP_kinases_N
SRD3_k127_4812557_1	1313172.YM304_33030	5.998e-66	237.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4CN2X@84992|Acidimicrobiia	84992|Acidimicrobiia	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRD3_k127_4812557_0	1229780.BN381_130124	9.806e-205	666.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,3UW6I@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRD3_k127_4812557_2	1123368.AUIS01000026_gene1459	1.805e-56	212.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,1RNWU@1236|Gammaproteobacteria,2NCT5@225057|Acidithiobacillales	225057|Acidithiobacillales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRD3_k127_4812557_3	1313172.YM304_32990	2.484e-46	174.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4CNAK@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRD3_k127_4834639_0	557599.MKAN_03230	9.759e-234	741.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,23CXI@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3,Urease_alpha
SRD3_k127_4834639_1	931627.MycrhDRAFT_2769	6.053e-29	118.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,232XE@1762|Mycobacteriaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.39	ko:K00146,ko:K11947	ko00360,ko00624,ko00643,ko01100,ko01120,ko01220,map00360,map00624,map00643,map01100,map01120,map01220	-	R02536,R05649	RC00075,RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRD3_k127_4878407_0	1120950.KB892720_gene1844	9.649e-90	299.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4DNGU@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3708c	Semialdhyde_dh,Semialdhyde_dhC
SRD3_k127_4878407_1	1121877.JQKF01000010_gene689	6.466e-47	177.0	COG0704@1|root,COG0704@2|Bacteria,2HGEH@201174|Actinobacteria,4CNCK@84992|Acidimicrobiia	84992|Acidimicrobiia	P	PhoU domain	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRD3_k127_4878407_2	706587.Desti_1303	1.436e-12	78.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1MV93@1224|Proteobacteria,42MQH@68525|delta/epsilon subdivisions,2WJPV@28221|Deltaproteobacteria,2MR91@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	iAF987.Gmet_3512	Aldedh,Pro_dh
SRD3_k127_4888411_6	1122611.KB903963_gene4641	1.708e-15	76.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4EFWD@85012|Streptosporangiales	201174|Actinobacteria	T	Elongation factor G C-terminus	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRD3_k127_4888411_8	66874.JOFS01000009_gene2744	2.646e-10	67.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRD3_k127_4888411_9	1177594.MIC448_1150009	5.798e-06	51.0	2BD34@1|root,326QM@2|Bacteria,2HC94@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4888411_1	351607.Acel_2052	4.97e-90	320.0	COG0215@1|root,COG4242@1|root,COG0215@2|Bacteria,COG4242@2|Bacteria,2I98G@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4888411_7	1394178.AWOO02000078_gene2031	6.651e-11	72.0	2E4AX@1|root,32Z6K@2|Bacteria,2GW4T@201174|Actinobacteria,4EJ1I@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF2017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2017
SRD3_k127_4888411_3	1236902.ANAS01000022_gene11	1.59e-33	146.0	COG2127@1|root,COG2127@2|Bacteria,2IQ3Z@201174|Actinobacteria,4EJYF@85012|Streptosporangiales	201174|Actinobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRD3_k127_4888411_2	446470.Snas_2430	4.757e-57	212.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4EYF0@85014|Glycomycetales	201174|Actinobacteria	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRD3_k127_4888411_0	1313172.YM304_38720	1.189e-96	329.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,4CMQ7@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRD3_k127_4888411_5	525909.Afer_1710	1.345e-16	93.0	COG0526@1|root,COG0526@2|Bacteria,2HGGP@201174|Actinobacteria,4CNDV@84992|Acidimicrobiia	84992|Acidimicrobiia	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
SRD3_k127_4888411_4	146922.JOFU01000028_gene5457	3.841e-32	134.0	COG0500@1|root,COG0500@2|Bacteria,2GKYW@201174|Actinobacteria	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4,Methyltransf_11,NUDIX
SRD3_k127_4906099_0	1313172.YM304_33140	1.488e-103	356.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,4CN31@84992|Acidimicrobiia	84992|Acidimicrobiia	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG
SRD3_k127_4906099_1	1313172.YM304_33170	1.348e-85	287.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4CMRI@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRD3_k127_4915284_2	1206730.BAGA01000079_gene1214	3.662e-63	228.0	COG1073@1|root,COG1073@2|Bacteria,2IFI1@201174|Actinobacteria,4FX9G@85025|Nocardiaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
SRD3_k127_4915284_3	1313172.YM304_38470	2.64e-53	199.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	1.3.1.34,3.1.2.6	ko:K00219,ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,Lactamase_B,Rhodanese
SRD3_k127_4915284_1	987059.RBXJA2T_01535	4.073e-79	274.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2VICE@28216|Betaproteobacteria,1KN7G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,NUDIX
SRD3_k127_4915284_0	1313172.YM304_38460	1.413e-104	346.0	COG0489@1|root,COG2151@1|root,COG0489@2|Bacteria,COG2151@2|Bacteria,2H1YI@201174|Actinobacteria,4CNPI@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRD3_k127_4942648_4	1136417.AZWE01000005_gene4552	3.026e-129	418.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4DBBX@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_4942648_5	1278078.G419_00060	6.58e-91	312.0	COG1960@1|root,COG1960@2|Bacteria,2GITF@201174|Actinobacteria,4FYBI@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE27	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_4942648_1	1229780.BN381_400017	2.927e-178	569.0	COG1960@1|root,COG1960@2|Bacteria,2GIXS@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_4942648_12	101510.RHA1_ro02974	3.829e-33	135.0	COG0454@1|root,COG4948@1|root,COG0456@2|Bacteria,COG4948@2|Bacteria,2HG8K@201174|Actinobacteria,4FYM4@85025|Nocardiaceae	201174|Actinobacteria	M	mandelate racemase muconate lactonizing	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	Acetyltransf_10,MR_MLE_C,MR_MLE_N
SRD3_k127_4942648_2	298655.KI912266_gene1261	1.609e-163	557.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4ES7N@85013|Frankiales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRD3_k127_4942648_7	882082.SaccyDRAFT_4634	7.239e-75	257.0	COG4977@1|root,COG4977@2|Bacteria,2I2KX@201174|Actinobacteria,4E4P6@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRD3_k127_4942648_8	767817.Desgi_3217	4.738e-70	248.0	COG4221@1|root,COG4221@2|Bacteria,1UIB4@1239|Firmicutes,25EG6@186801|Clostridia,265GT@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_4942648_0	1123320.KB889585_gene1868	3.612e-219	691.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_4942648_11	471852.Tcur_1893	7.054e-62	219.0	COG1225@1|root,COG1225@2|Bacteria,2IFB1@201174|Actinobacteria,4EJGB@85012|Streptosporangiales	201174|Actinobacteria	O	Redoxin	bcpB	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRD3_k127_4942648_9	1278073.MYSTI_04826	6.612e-67	240.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria	1224|Proteobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD3_k127_4942648_10	1123320.KB889685_gene2189	1.193e-62	232.0	28K5H@1|root,2Z9U4@2|Bacteria,2GKEQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4942648_3	326424.FRAAL3421	1.375e-134	451.0	COG0318@1|root,COG0318@2|Bacteria,2I91U@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_4942648_6	1123320.KB889697_gene9029	1.691e-75	259.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	2|Bacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_4986951_9	929712.KI912613_gene3703	3.545e-17	86.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CR8Y@84995|Rubrobacteria	84995|Rubrobacteria	T	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRD3_k127_4986951_7	1380390.JIAT01000009_gene648	1.31e-35	138.0	COG0640@1|root,COG0640@2|Bacteria,2GYV0@201174|Actinobacteria,4CQNZ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRD3_k127_4986951_5	557599.MKAN_18905	3.629e-57	211.0	COG5418@1|root,COG5418@2|Bacteria,2H2GT@201174|Actinobacteria,23CAT@1762|Mycobacteriaceae	201174|Actinobacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4986951_8	68170.KL590502_gene1978	5.508e-25	115.0	COG1366@1|root,COG1366@2|Bacteria,2II36@201174|Actinobacteria,4E3T4@85010|Pseudonocardiales	201174|Actinobacteria	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	-	-	-	-	-	-	-	-	-	-	-	-	MEDS,STAS_2
SRD3_k127_4986951_1	264732.Moth_2154	2.7e-153	498.0	COG1215@1|root,COG1215@2|Bacteria,1TSK5@1239|Firmicutes,25B0I@186801|Clostridia,42F57@68295|Thermoanaerobacterales	186801|Clostridia	M	Glycosyl transferase family group 2	-	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3,Glyco_trans_2_3
SRD3_k127_4986951_3	1120950.KB892742_gene3061	1.88e-60	211.0	COG1917@1|root,COG1917@2|Bacteria,2IFSF@201174|Actinobacteria,4DSFX@85009|Propionibacteriales	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRD3_k127_4986951_0	1313172.YM304_41670	2.112e-197	630.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria	201174|Actinobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRD3_k127_4986951_2	298655.KI912266_gene5727	1.712e-84	302.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRD3_k127_4986951_4	298654.FraEuI1c_1589	9.682e-58	209.0	COG0500@1|root,COG0500@2|Bacteria,2I3S9@201174|Actinobacteria	201174|Actinobacteria	Q	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRD3_k127_4986951_6	931627.MycrhDRAFT_1243	9.87e-42	171.0	COG3971@1|root,COG3971@2|Bacteria	2|Bacteria	Q	2-oxopent-4-enoate hydratase activity	mhpD	-	4.1.1.77,4.2.1.80	ko:K01617,ko:K02554	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R02601,R02602,R04781,R05374	RC00750,RC00751,RC01213,RC02672	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
SRD3_k127_4988380_9	1123258.AQXZ01000007_gene264	4.785e-34	136.0	COG2114@1|root,COG2114@2|Bacteria,2I900@201174|Actinobacteria,4FVU8@85025|Nocardiaceae	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1647	Guanylate_cyc
SRD3_k127_4988380_1	247156.NFA_3020	9.269e-100	365.0	COG0769@1|root,COG0769@2|Bacteria,2I2TV@201174|Actinobacteria,4FUN3@85025|Nocardiaceae	201174|Actinobacteria	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
SRD3_k127_4988380_0	1229780.BN381_430032	2.099e-150	488.0	COG0204@1|root,COG0560@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,2GKVA@201174|Actinobacteria,3UWPE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Phosphate acyltransferases	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRD3_k127_4988380_5	1229780.BN381_430035	2.88e-73	258.0	COG0583@1|root,COG0583@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
SRD3_k127_4988380_7	1435356.Y013_00750	4.987e-44	169.0	COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria,4G0P0@85025|Nocardiaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD3_k127_4988380_6	1157637.KB892155_gene7704	3.279e-48	190.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the UPF0301 (AlgH) family	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
SRD3_k127_4988380_3	404589.Anae109_1007	8.881e-94	317.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42Z1A@68525|delta/epsilon subdivisions,2WU2C@28221|Deltaproteobacteria,2Z0AD@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRD3_k127_4988380_2	981369.JQMJ01000004_gene3953	5.782e-94	320.0	COG1295@1|root,COG1295@2|Bacteria,2HMQ0@201174|Actinobacteria,2NGCJ@228398|Streptacidiphilus	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
SRD3_k127_4988380_4	1150599.MPHLEI_14604	2.041e-87	300.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,233TC@1762|Mycobacteriaceae	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_4988380_8	1288083.AUKR01000023_gene434	1.801e-34	135.0	COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRD3_k127_4995963_10	1150864.MILUP08_42732	1.332e-05	55.0	29HRQ@1|root,304NY@2|Bacteria,2II7T@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_4995963_5	1229780.BN381_80351	2.012e-57	211.0	COG0266@1|root,COG0266@2|Bacteria,2H39J@201174|Actinobacteria	201174|Actinobacteria	L	formamidopyrimidine-DNA glycosylase	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRD3_k127_4995963_0	1229780.BN381_310078	1.259e-162	520.0	COG1035@1|root,COG1146@1|root,COG1035@2|Bacteria,COG1146@2|Bacteria,2GRHK@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4_9,FrhB_FdhB_C,FrhB_FdhB_N
SRD3_k127_4995963_2	469383.Cwoe_5791	1.521e-89	315.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4CPSB@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRD3_k127_4995963_4	1313172.YM304_10000	1.363e-63	235.0	COG0406@1|root,COG0406@2|Bacteria,2GK8N@201174|Actinobacteria,4CNCR@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRD3_k127_4995963_8	1172188.KB911823_gene510	6.049e-29	122.0	298YA@1|root,2ZW25@2|Bacteria,2GIYI@201174|Actinobacteria,4FGZE@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
SRD3_k127_4995963_3	357808.RoseRS_0006	1.72e-72	259.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi,375HF@32061|Chloroflexia	32061|Chloroflexia	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
SRD3_k127_4995963_9	414684.RC1_1545	1.578e-16	93.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,2UBYD@28211|Alphaproteobacteria,2JTBZ@204441|Rhodospirillales	204441|Rhodospirillales	T	Phosphohistidine phosphatase SixA	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRD3_k127_4995963_6	1051632.TPY_2564	5.19e-48	189.0	COG2845@1|root,COG2845@2|Bacteria	2|Bacteria	Q	Protein of unknown function (DUF459)	-	-	-	ko:K09795	-	-	-	-	ko00000	-	-	-	DUF459,Lipase_GDSL_2,LysM
SRD3_k127_4995963_1	298655.KI912266_gene1879	3.902e-141	462.0	COG1696@1|root,COG1696@2|Bacteria,2GM6Z@201174|Actinobacteria,4EUU2@85013|Frankiales	201174|Actinobacteria	M	MBOAT, membrane-bound O-acyltransferase family	algI	-	-	ko:K03739,ko:K19294	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
SRD3_k127_4995963_7	1313172.YM304_09920	5.966e-29	116.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4CMXZ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Electron transfer flavoprotein domain	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRD3_k127_5009237_2	1122609.AUGT01000012_gene4501	1.735e-41	156.0	COG4221@1|root,COG4221@2|Bacteria,2I8VU@201174|Actinobacteria,4DPNG@85009|Propionibacteriales	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_5009237_0	58123.JOFJ01000003_gene2072	6.699e-208	662.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,4EMIP@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	cyp51	GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0008398,GO:0016125,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0032451,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0055114,GO:0070988,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901615	1.14.13.70	ko:K05917	ko00100,ko01100,ko01110,ko01130,map00100,map01100,map01110,map01130	M00101	R05640,R05731	RC01442	ko00000,ko00001,ko00002,ko00199,ko01000	-	-	-	p450
SRD3_k127_5009237_3	1278078.G419_21374	1.436e-15	87.0	COG1141@1|root,COG1141@2|Bacteria,2GS47@201174|Actinobacteria,4G3V5@85025|Nocardiaceae	201174|Actinobacteria	C	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13,Fer4_15
SRD3_k127_5009237_1	1394178.AWOO02000025_gene4982	1.548e-70	242.0	28NTV@1|root,2ZBSB@2|Bacteria,2GS03@201174|Actinobacteria,4EMSC@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5017448_5	644283.Micau_0858	8.4e-42	164.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria,4D8RZ@85008|Micromonosporales	201174|Actinobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRD3_k127_5017448_1	1169161.KB897735_gene5149	6.724e-104	353.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria	201174|Actinobacteria	G	synthase	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRD3_k127_5017448_3	1380347.JNII01000007_gene76	1.134e-82	291.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycerate kinase type-1 family	garK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRD3_k127_5017448_4	1229780.BN381_150092	4.782e-61	220.0	COG1215@1|root,COG1215@2|Bacteria,2GMKV@201174|Actinobacteria,3UXD7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Glycosyl transferase family 2	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
SRD3_k127_5017448_0	525909.Afer_1848	9.346e-172	548.0	COG0498@1|root,COG0498@2|Bacteria,2GNM0@201174|Actinobacteria	201174|Actinobacteria	E	Threonine synthase	thrC3	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD3_k127_5017448_7	1485545.JQLW01000009_gene132	4.221e-29	124.0	COG1977@1|root,COG1977@2|Bacteria,1N4Z0@1224|Proteobacteria	1224|Proteobacteria	H	Molybdopterin converting factor, small subunit	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRD3_k127_5017448_2	469383.Cwoe_4184	1.239e-92	323.0	COG2114@1|root,COG5002@1|root,COG2114@2|Bacteria,COG5002@2|Bacteria,2GJRI@201174|Actinobacteria,4CPDK@84995|Rubrobacteria	84995|Rubrobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
SRD3_k127_5017448_6	365528.KB891234_gene121	4.181e-29	117.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4ERKH@85013|Frankiales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groEL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRD3_k127_5044502_1	1206733.BAGC01000035_gene3639	5.834e-132	426.0	COG2267@1|root,COG2267@2|Bacteria,2I3AI@201174|Actinobacteria,4FYMF@85025|Nocardiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	dhmA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
SRD3_k127_5044502_0	298654.FraEuI1c_3065	5.315e-292	900.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
SRD3_k127_5044502_3	1068980.ARVW01000001_gene8139	2.762e-35	145.0	COG0511@1|root,COG0511@2|Bacteria,2GMCA@201174|Actinobacteria	201174|Actinobacteria	I	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRD3_k127_5044502_2	1123024.AUII01000028_gene2518	9.819e-54	195.0	COG0406@1|root,COG0406@2|Bacteria,2HRP2@201174|Actinobacteria,4EAZ6@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRD3_k127_5044502_4	1229780.BN381_170039	3.779e-10	60.0	COG1579@1|root,COG1579@2|Bacteria,2GP84@201174|Actinobacteria,3UWX1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Zn-ribbon protein, possibly nucleic acid-binding	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRD3_k127_5056215_1	345341.KUTG_01809	6.505e-47	172.0	2FEGF@1|root,346G0@2|Bacteria,2H549@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5056215_0	1229780.BN381_130019	6.404e-184	584.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,3UWF7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRD3_k127_5063799_3	1229780.BN381_80407	1.544e-115	391.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,3UWEE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRD3_k127_5063799_6	525909.Afer_1081	9.466e-67	233.0	COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,4CN3I@84992|Acidimicrobiia	84992|Acidimicrobiia	T	ANTAR	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
SRD3_k127_5063799_10	1313172.YM304_21360	7.16e-12	72.0	29B43@1|root,2ZY2Q@2|Bacteria,2HD3P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5063799_7	1172188.KB911820_gene3136	3.184e-27	127.0	2DG80@1|root,2ZUVA@2|Bacteria,2GWMN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5063799_2	1313172.YM304_21340	2.857e-121	404.0	COG0331@1|root,COG0331@2|Bacteria,2GME0@201174|Actinobacteria,4CMPZ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRD3_k127_5063799_4	525909.Afer_1086	2.663e-108	369.0	COG0332@1|root,COG0332@2|Bacteria,2GJP8@201174|Actinobacteria,4CMQV@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRD3_k127_5063799_5	1449353.JQMQ01000005_gene1490	7.44e-84	286.0	COG1028@1|root,COG1028@2|Bacteria,2GK6C@201174|Actinobacteria,2NG0C@228398|Streptacidiphilus	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD3_k127_5063799_8	1313172.YM304_21310	2.607e-23	104.0	COG0236@1|root,COG0236@2|Bacteria,2HGA0@201174|Actinobacteria,4CN8U@84992|Acidimicrobiia	84992|Acidimicrobiia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRD3_k127_5063799_1	525909.Afer_1089	6.631e-148	482.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria,4CMVV@84992|Acidimicrobiia	84992|Acidimicrobiia	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRD3_k127_5063799_0	1121877.JQKF01000021_gene2202	5.173e-192	616.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CMUC@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
SRD3_k127_5063799_9	649831.L083_2136	1.938e-12	79.0	COG1287@1|root,COG1287@2|Bacteria,2HBRT@201174|Actinobacteria,4D9I9@85008|Micromonosporales	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRD3_k127_5099215_2	1869.MB27_00325	1.648e-27	124.0	COG3663@1|root,COG3663@2|Bacteria,2GNS5@201174|Actinobacteria,4DDIB@85008|Micromonosporales	201174|Actinobacteria	L	U mismatch-specific DNA glycosylase	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRD3_k127_5099215_0	1282876.BAOK01000001_gene2087	2.67e-103	345.0	28M2T@1|root,2ZAH6@2|Bacteria,1R6GW@1224|Proteobacteria,2U25T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5099215_1	28042.GU90_03955	9.003e-39	167.0	COG3173@1|root,COG3173@2|Bacteria,2HU7E@201174|Actinobacteria,4DYKS@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRD3_k127_5113777_0	1380356.JNIK01000017_gene2900	9.17e-172	572.0	COG3857@1|root,COG3857@2|Bacteria,2I6QC@201174|Actinobacteria	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRD3_k127_5126047_0	1394178.AWOO02000115_gene892	2.771e-103	349.0	COG0491@1|root,COG0491@2|Bacteria,2HFVZ@201174|Actinobacteria,4EFG8@85012|Streptosporangiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	ko:K05555	ko01057,ko01130,map01057,map01130	M00778	R09305	-	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	Lactamase_B
SRD3_k127_5126047_1	1538295.JY96_06200	3.654e-60	220.0	2E963@1|root,333ES@2|Bacteria,1QW4F@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2804)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2804
SRD3_k127_5148802_3	298654.FraEuI1c_4577	9.716e-16	85.0	2EFF7@1|root,33981@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5148802_0	257310.BB0585	1.276e-98	329.0	COG1024@1|root,COG1024@2|Bacteria,1Q51H@1224|Proteobacteria,2VIMS@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD3_k127_5148802_2	525909.Afer_0452	2.107e-29	133.0	COG3764@1|root,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	srtA	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRD3_k127_5148802_1	365528.KB891252_gene5755	3.727e-90	309.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria,4ERG2@85013|Frankiales	201174|Actinobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
SRD3_k127_5179697_3	469383.Cwoe_4178	4.296e-60	214.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria	201174|Actinobacteria	P	Magnesium transport protein CorA	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRD3_k127_5179697_1	1313172.YM304_22570	1.041e-121	398.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CMPY@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
SRD3_k127_5179697_6	196162.Noca_4290	1.785e-29	130.0	COG2172@1|root,COG2172@2|Bacteria,2IBHV@201174|Actinobacteria,4DRB2@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,PAS
SRD3_k127_5179697_4	1298863.AUEP01000008_gene1240	2.992e-57	203.0	COG0346@1|root,COG0346@2|Bacteria,2HKRN@201174|Actinobacteria,4DPT9@85009|Propionibacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRD3_k127_5179697_2	1048339.KB913029_gene3593	1.257e-72	273.0	COG2172@1|root,COG2203@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2GKEF@201174|Actinobacteria,4EVA5@85013|Frankiales	201174|Actinobacteria	T	Serine phosphatase RsbU, regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c_2,PAS_3,PAS_4,PAS_9,SpoIIE
SRD3_k127_5179697_0	1278078.G419_19935	4.887e-132	435.0	COG3173@1|root,COG3173@2|Bacteria,2GSTN@201174|Actinobacteria,4FY7Q@85025|Nocardiaceae	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRD3_k127_5179697_5	1206741.BAFX01000100_gene979	1.743e-35	136.0	2BYTM@1|root,2Z7KC@2|Bacteria,2GJ6K@201174|Actinobacteria,4FU8Z@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5182070_0	1120936.KB907209_gene1795	1.649e-101	351.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4EMZ3@85012|Streptosporangiales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD3_k127_5182070_1	298654.FraEuI1c_4913	1.288e-29	136.0	COG0438@1|root,COG0438@2|Bacteria,2GK8D@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD3_k127_519694_1	266117.Rxyl_2763	7.96e-166	548.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CQ32@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRD3_k127_519694_0	1123322.KB904650_gene1803	2.34e-166	558.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria	201174|Actinobacteria	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
SRD3_k127_519694_3	1254432.SCE1572_30125	2.342e-52	209.0	COG3437@1|root,COG3829@1|root,COG3852@1|root,COG4251@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG3852@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,43CDW@68525|delta/epsilon subdivisions,2X7X2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
SRD3_k127_519694_2	66373.JOFQ01000001_gene1740	8.495e-70	262.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
SRD3_k127_519694_4	298654.FraEuI1c_6924	9.344e-10	66.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria,4EWI4@85013|Frankiales	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRD3_k127_523212_0	525909.Afer_0111	1.473e-179	572.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4CMX1@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ACT domain	ask	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRD3_k127_523212_1	1157637.KB892101_gene2516	4.935e-51	183.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3708c	Semialdhyde_dh,Semialdhyde_dhC
SRD3_k127_5247763_0	1137269.AZWL01000001_gene5688	6.947e-108	357.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked	agpS	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRD3_k127_5247763_1	1463825.JNXC01000017_gene6951	1.444e-107	358.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,4DXXN@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD3_k127_5279990_0	1121928.AUHE01000008_gene2988	8.964e-78	264.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4GACD@85026|Gordoniaceae	201174|Actinobacteria	E	Glutamine synthetase, beta-Grasp domain	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRD3_k127_5279990_1	1313172.YM304_38350	4.541e-77	264.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4CN27@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRD3_k127_5279990_3	1229780.BN381_100104	8.553e-24	114.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRD3_k127_5279990_2	1313172.YM304_38400	3.155e-60	216.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	xdh	-	1.17.1.4,1.2.5.3,1.3.99.16	ko:K00087,ko:K03518,ko:K07302	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRD3_k127_5314797_0	235985.BBPN01000002_gene5137	5.889e-57	211.0	COG4677@1|root,COG4677@2|Bacteria,2I5JZ@201174|Actinobacteria,2NKFF@228398|Streptacidiphilus	201174|Actinobacteria	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRD3_k127_5314797_1	1121933.AUHH01000009_gene785	4.349e-09	67.0	COG0438@1|root,COG0438@2|Bacteria,2HFIU@201174|Actinobacteria,4DVZE@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRD3_k127_5316156_4	1041522.MCOL_V219496	1.346e-10	71.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,2346V@1762|Mycobacteriaceae	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	pepQ	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRD3_k127_5316156_2	1229780.BN381_50135	3.077e-46	189.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,3UWWA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786,ko:K16021	ko00400,ko01051,ko01100,ko01110,ko01130,ko01230,map00400,map01051,map01100,map01110,map01130,map01230	M00022	R03084,R06593	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRD3_k127_5316156_1	1313172.YM304_20360	8.374e-105	350.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,4CMXJ@84992|Acidimicrobiia	84992|Acidimicrobiia	H	3-dehydroquinate synthase	aroB	-	-	ko:K16020	ko01051,ko01130,map01051,map01130	-	R06592	RC00847	ko00000,ko00001	-	-	-	DHQ_synthase
SRD3_k127_5316156_3	867903.ThesuDRAFT_02352	5.344e-26	116.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,3WCII@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
SRD3_k127_5316156_0	1313172.YM304_20340	1.091e-114	377.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4CMPX@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRD3_k127_5317200_0	1158292.JPOE01000002_gene3210	3.288e-20	105.0	COG1216@1|root,COG1216@2|Bacteria,1RJPX@1224|Proteobacteria	1224|Proteobacteria	E	Glycosyl transferase, family 2	-	-	2.4.1.175,2.4.1.226	ko:K13500	ko00532,ko01100,map00532,map01100	-	R04603,R05931,R05932,R05933,R05934,R07336	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glyco_transf_7C,Glycos_transf_2
SRD3_k127_5317743_3	525909.Afer_1951	9.39e-23	106.0	2A58G@1|root,30TXM@2|Bacteria,2HG9Z@201174|Actinobacteria,4CN8R@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5317743_2	1229780.BN381_130016	9.302e-79	274.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,3UWG1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRD3_k127_5317743_4	1229780.BN381_130015	5.996e-17	93.0	COG1828@1|root,COG1828@2|Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.2.6,6.3.5.3	ko:K01923,ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463,R04591	RC00010,RC00064,RC00162,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
SRD3_k127_5317743_1	1123371.ATXH01000013_gene1529	1.026e-97	333.0	COG0152@1|root,COG0152@2|Bacteria,2GH07@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRD3_k127_5317743_0	1313172.YM304_38920	9.631e-157	505.0	COG0015@1|root,COG0015@2|Bacteria,2GKBR@201174|Actinobacteria,4CMWU@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Adenylosuccinate lyase C-terminus	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRD3_k127_5326828_5	351607.Acel_0744	2.503e-78	267.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4ERP0@85013|Frankiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	nodI	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
SRD3_k127_5326828_2	408672.NBCG_00750	1.824e-152	496.0	COG1236@1|root,COG1236@2|Bacteria,2HEXB@201174|Actinobacteria,4DQ4R@85009|Propionibacteriales	201174|Actinobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,RMMBL
SRD3_k127_5326828_7	83332.Rv0323c	5.144e-58	211.0	COG2120@1|root,COG2120@2|Bacteria,2IJ0C@201174|Actinobacteria,23BTH@1762|Mycobacteriaceae	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRD3_k127_5326828_9	1122933.JNIY01000010_gene1297	3.097e-32	130.0	COG3439@1|root,COG3439@2|Bacteria,2IKVF@201174|Actinobacteria,4F2SF@85016|Cellulomonadaceae	201174|Actinobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
SRD3_k127_5326828_10	1229780.BN381_130242	9.044e-29	123.0	COG1937@1|root,COG1937@2|Bacteria,2IQ7U@201174|Actinobacteria,3UWY5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
SRD3_k127_5326828_8	1463920.JOGB01000005_gene1907	1.692e-45	169.0	COG0526@1|root,COG0526@2|Bacteria,2IKP1@201174|Actinobacteria	201174|Actinobacteria	CO	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
SRD3_k127_5326828_16	29581.BW37_02044	0.0003803	51.0	COG0840@1|root,COG4191@1|root,COG0840@2|Bacteria,COG4191@2|Bacteria,1NC2U@1224|Proteobacteria,2VS77@28216|Betaproteobacteria,476KI@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRD3_k127_5326828_0	350058.Mvan_4106	0.0	1255.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,2337W@1762|Mycobacteriaceae	201174|Actinobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007,ko:K21787	ko00333,ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01130,ko01200,map00333,map00620,map00680,map00710,map00720,map01100,map01120,map01130,map01200	M00169,M00171,M00172,M00173,M00374,M00837,M00838	R00199,R00206,R11662,R11673	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRD3_k127_5326828_1	1449353.JQMQ01000005_gene590	2.558e-156	516.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,2NHHA@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_5326828_3	1206731.BAGB01000061_gene3436	5.808e-143	471.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4FX8C@85025|Nocardiaceae	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_5326828_4	1123320.KB889668_gene3369	4.615e-127	437.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria	201174|Actinobacteria	IQ	Peptidase S15	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRD3_k127_5326828_14	543632.JOJL01000023_gene1836	8.711e-07	60.0	2EA32@1|root,33485@2|Bacteria,2IN6C@201174|Actinobacteria,4DEKJ@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5326828_12	219305.MCAG_01671	8.093e-19	90.0	2E65S@1|root,330UF@2|Bacteria,2IMEQ@201174|Actinobacteria,4DERM@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF3817)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3817
SRD3_k127_5326828_13	875328.JDM601_2666	8.31e-13	81.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,234RM@1762|Mycobacteriaceae	201174|Actinobacteria	V	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRD3_k127_5326828_11	479433.Caci_2615	1.389e-24	104.0	2BZ6B@1|root,336KR@2|Bacteria,2IQEV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5326828_6	525909.Afer_0785	4.097e-78	281.0	COG2385@1|root,COG2385@2|Bacteria,2HGMW@201174|Actinobacteria,4CNNC@84992|Acidimicrobiia	84992|Acidimicrobiia	D	sporulation resulting in formation of a cellular spore	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_53692_6	1313172.YM304_21620	5.091e-36	154.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CMVA@84992|Acidimicrobiia	84992|Acidimicrobiia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,UVR,UvrC_HhH_N
SRD3_k127_53692_3	1313172.YM304_21660	2.201e-84	296.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4CMXB@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRD3_k127_53692_4	582515.KR51_00015010	1.621e-53	213.0	COG0391@1|root,COG0391@2|Bacteria,1G0R0@1117|Cyanobacteria	1117|Cyanobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRD3_k127_53692_1	1121877.JQKF01000028_gene2134	2.01e-146	477.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CMQP@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRD3_k127_53692_0	1229780.BN381_80402	8.583e-155	500.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,3UWA2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Phosphoglycerate kinase	pgk	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRD3_k127_53692_2	1313172.YM304_21690	1.572e-86	305.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4CMZ0@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRD3_k127_53692_7	1121877.JQKF01000028_gene2137	6.333e-17	83.0	COG1314@1|root,COG1314@2|Bacteria,2HGDT@201174|Actinobacteria,4CNCC@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRD3_k127_53692_5	1463901.JOIY01000029_gene430	1.167e-48	196.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type dipeptide transport system, periplasmic component	oppA	GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0022857,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043295,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072341,GO:1900750,GO:1901681,GO:1904680	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRD3_k127_5372255_6	1379270.AUXF01000004_gene3295	3.286e-17	88.0	COG0354@1|root,COG0354@2|Bacteria,1ZTMX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Glycine cleavage T-protein C-terminal barrel domain	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRD3_k127_5372255_5	390989.JOEG01000004_gene3753	8.096e-47	188.0	COG5002@1|root,COG5002@2|Bacteria,2GMH4@201174|Actinobacteria,4DAGR@85008|Micromonosporales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	baeS	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRD3_k127_5372255_3	1386089.N865_08170	1.979e-62	222.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4FGFE@85021|Intrasporangiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRD3_k127_5372255_2	1313172.YM304_24270	2.174e-75	268.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4CN2P@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Indole-3-glycerol phosphate synthase	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRD3_k127_5372255_4	525909.Afer_1096	4.245e-62	228.0	COG0135@1|root,COG0135@2|Bacteria,2IHPP@201174|Actinobacteria,4CN2A@84992|Acidimicrobiia	84992|Acidimicrobiia	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRD3_k127_5372255_0	1229780.BN381_50177	6.865e-175	567.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,3UWAH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRD3_k127_5372255_1	1229780.BN381_50178	2.889e-89	312.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,3UWK3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRD3_k127_5376417_0	1229780.BN381_10277	9.203e-131	424.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria,3UXGG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRD3_k127_5376417_3	1048339.KB913029_gene603	2.989e-12	79.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRD3_k127_5376417_2	557599.MKAN_27555	2.264e-50	189.0	COG2050@1|root,COG2050@2|Bacteria,2GV7U@201174|Actinobacteria,23BQU@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRD3_k127_5376417_1	1122614.JHZF01000011_gene869	2.934e-104	353.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TTRD@28211|Alphaproteobacteria,2PF1U@252301|Oceanicola	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_5376417_4	2045.KR76_08860	4.14e-10	71.0	COG3396@1|root,COG3396@2|Bacteria,2GKXZ@201174|Actinobacteria,4DMYE@85009|Propionibacteriales	201174|Actinobacteria	S	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like	-	-	-	-	-	-	-	-	-	-	-	-	MiaE_2
SRD3_k127_5386471_2	1313172.YM304_20510	1.218e-38	149.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4CMYE@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRD3_k127_5386471_0	446462.Amir_3103	1.243e-167	537.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4DXAM@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRD3_k127_5386471_1	1313172.YM304_20530	3.362e-51	193.0	COG1198@1|root,COG1198@2|Bacteria,2HG9D@201174|Actinobacteria,4CN7P@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	-	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRD3_k127_540430_3	525909.Afer_0595	2.042e-19	95.0	2ANAN@1|root,31D8Y@2|Bacteria,2HGVW@201174|Actinobacteria,4CNX0@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_540430_4	1232437.KL662010_gene1557	7.518e-12	74.0	COG1853@1|root,COG1853@2|Bacteria,1QNV2@1224|Proteobacteria,42TD3@68525|delta/epsilon subdivisions,2WPRM@28221|Deltaproteobacteria,2MK7Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRD3_k127_540430_2	1313172.YM304_20220	1.049e-35	155.0	2DMMI@1|root,32SFN@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3151)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3151
SRD3_k127_540430_0	926569.ANT_07690	8.289e-129	425.0	COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRD3_k127_540430_1	543632.JOJL01000002_gene8158	3.584e-48	175.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,4DANW@85008|Micromonosporales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD3_k127_5408685_0	631362.Thi970DRAFT_01081	1.579e-105	355.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1WWNU@135613|Chromatiales	135613|Chromatiales	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRD3_k127_5408685_1	1229780.BN381_290120	8.836e-87	313.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,3UWID@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.6	ko:K00611,ko:K13252	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRD3_k127_5408685_2	1229780.BN381_290119	1.006e-55	205.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,3UWW0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Arginine repressor, DNA binding domain	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRD3_k127_5408685_3	1348663.KCH_14570	1.115e-51	191.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,2M2IH@2063|Kitasatospora	201174|Actinobacteria	E	Arginosuccinate synthase	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1658	Arginosuc_synth
SRD3_k127_5419320_1	882083.SacmaDRAFT_1782	5.815e-208	655.0	COG0174@1|root,COG0174@2|Bacteria,2GM3K@201174|Actinobacteria,4DXD6@85010|Pseudonocardiales	201174|Actinobacteria	E	Glutamine synthetase, catalytic domain	glnA4	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
SRD3_k127_5419320_0	103733.JNYO01000021_gene6839	4.282e-208	660.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DZU8@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	aldC	-	1.2.1.3,1.2.1.39,1.2.1.8	ko:K00128,ko:K00130,ko:K00146	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD3_k127_5419320_2	1206733.BAGC01000040_gene1415	9.962e-114	372.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4FYG6@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD3_k127_5419320_3	1223523.H340_13047	6.963e-66	233.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria	201174|Actinobacteria	K	peptidase C26	-	-	4.1.3.27	ko:K01658,ko:K07010	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Peptidase_C26
SRD3_k127_5419320_4	235985.BBPN01000007_gene3476	1.155e-34	147.0	COG3550@1|root,COG3550@2|Bacteria,2GJ1X@201174|Actinobacteria,2NI60@228398|Streptacidiphilus	201174|Actinobacteria	S	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRD3_k127_5525990_4	1380390.JIAT01000012_gene3001	4.29e-41	157.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRD3_k127_5525990_0	1380390.JIAT01000012_gene3002	4.004e-112	382.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRD3_k127_5525990_1	1380390.JIAT01000012_gene3003	2.722e-98	335.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRD3_k127_5525990_3	886293.Sinac_4403	1.139e-43	180.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	-	-	-	ko:K18844	-	-	-	-	ko00000,ko01504	-	-	-	APH
SRD3_k127_5525990_2	886293.Sinac_4405	1.22e-69	246.0	COG3394@1|root,COG3394@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
SRD3_k127_5525990_5	1043493.BBLU01000006_gene2102	0.0003434	53.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	rimJ2	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRD3_k127_5527646_4	316274.Haur_1124	3.73e-16	80.0	COG5282@1|root,COG5282@2|Bacteria,2G800@200795|Chloroflexi,3758B@32061|Chloroflexia	32061|Chloroflexia	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRD3_k127_5527646_0	1313172.YM304_37680	4.484e-84	291.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4CN76@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
SRD3_k127_5527646_2	1121877.JQKF01000035_gene1977	3.472e-60	214.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CNRA@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRD3_k127_5527646_1	1229780.BN381_110024	5.399e-76	259.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,3UWJV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
SRD3_k127_5527646_3	525909.Afer_1911	7.935e-47	182.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4CNEH@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRD3_k127_5530108_0	42256.RradSPS_0307	5.413e-67	242.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria	201174|Actinobacteria	S	CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
SRD3_k127_5530108_1	1306990.BARG01000081_gene8218	1.778e-26	115.0	COG1051@1|root,COG1051@2|Bacteria,2I2N2@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the NUDIX hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRD3_k127_5543530_0	105420.BBPO01000014_gene6113	3.17e-80	274.0	COG0500@1|root,COG2835@1|root,COG2226@2|Bacteria,COG2835@2|Bacteria,2I34F@201174|Actinobacteria,2NNFP@228398|Streptacidiphilus	201174|Actinobacteria	Q	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRD3_k127_5543530_1	298655.KI912267_gene7072	1.044e-78	278.0	COG2244@1|root,COG2244@2|Bacteria,2IAQ4@201174|Actinobacteria	201174|Actinobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5549883_3	298654.FraEuI1c_0845	1.556e-67	257.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	LysM,Polysacc_deac_1
SRD3_k127_5549883_1	981369.JQMJ01000004_gene449	2.444e-110	385.0	COG0842@1|root,COG0842@2|Bacteria,2HNB6@201174|Actinobacteria,2NHZ8@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
SRD3_k127_5549883_2	882083.SacmaDRAFT_2729	1.538e-98	334.0	COG0842@1|root,COG0842@2|Bacteria,2IART@201174|Actinobacteria,4E1XJ@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
SRD3_k127_5549883_0	1125971.ASJB01000099_gene2288	4.302e-122	402.0	COG1131@1|root,COG1131@2|Bacteria,2IBJD@201174|Actinobacteria,4E1YQ@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRD3_k127_5555631_3	1056816.JAFQ01000004_gene1090	9.622e-07	53.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4FX1G@85025|Nocardiaceae	201174|Actinobacteria	P	Sulfate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRD3_k127_5555631_0	1123322.KB904735_gene1475	1.552e-37	156.0	COG3448@1|root,COG3448@2|Bacteria,2IJXV@201174|Actinobacteria	201174|Actinobacteria	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
SRD3_k127_5555631_2	1283299.AUKG01000003_gene359	8.514e-20	102.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CQXK@84995|Rubrobacteria	84995|Rubrobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRD3_k127_5555631_5	1449068.JMLQ01000013_gene1457	0.0004875	51.0	COG1233@1|root,COG1233@2|Bacteria,2IAZ7@201174|Actinobacteria	201174|Actinobacteria	Q	COG1233 Phytoene dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5555631_1	1229780.BN381_210083	7.743e-22	103.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_5612023_0	1380347.JNII01000006_gene1603	1.598e-179	570.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4ES69@85013|Frankiales	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRD3_k127_5612023_2	1120950.KB892823_gene530	5.446e-119	390.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4DNTD@85009|Propionibacteriales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	sdhB1	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0247c	Fer2_3,Fer4_8
SRD3_k127_5612023_6	1121877.JQKF01000016_gene135	2.034e-12	71.0	2BA7Z@1|root,323N2@2|Bacteria,2HH2A@201174|Actinobacteria,4CP2D@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5612023_4	1356854.N007_11525	8.292e-77	274.0	COG1686@1|root,COG1686@2|Bacteria,1VZJP@1239|Firmicutes	1239|Firmicutes	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
SRD3_k127_5612023_3	350054.Mflv_5155	1.382e-86	297.0	COG0596@1|root,COG0596@2|Bacteria,2GY3A@201174|Actinobacteria,236DE@1762|Mycobacteriaceae	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRD3_k127_5612023_1	1120950.KB892812_gene6966	1.151e-132	431.0	COG0039@1|root,COG0039@2|Bacteria,2GJHS@201174|Actinobacteria,4DN1I@85009|Propionibacteriales	201174|Actinobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRD3_k127_5612023_5	1121877.JQKF01000035_gene1958	5.402e-61	211.0	COG0538@1|root,COG0538@2|Bacteria,2IBM8@201174|Actinobacteria,4CNHG@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRD3_k127_5612105_1	408672.NBCG_00165	1.101e-97	329.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria,4DN5F@85009|Propionibacteriales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRD3_k127_5612105_3	526226.Gbro_3356	1.12e-24	115.0	2B3K7@1|root,31W9H@2|Bacteria,2HXPZ@201174|Actinobacteria,4GGKS@85026|Gordoniaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5612105_4	1122247.C731_0984	9.254e-24	103.0	2AEPZ@1|root,314K8@2|Bacteria,2IEBE@201174|Actinobacteria,236M5@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRD3_k127_5612105_5	1122247.C731_0984	1.235e-11	75.0	2AEPZ@1|root,314K8@2|Bacteria,2IEBE@201174|Actinobacteria,236M5@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRD3_k127_5612105_2	164757.Mjls_4023	5.422e-38	155.0	COG0778@1|root,COG0778@2|Bacteria,2GKG5@201174|Actinobacteria,23EWU@1762|Mycobacteriaceae	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRD3_k127_5612105_0	443255.SCLAV_4903	3.137e-146	470.0	COG1960@1|root,COG1960@2|Bacteria,2GJHM@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRD3_k127_5662970_1	1944.JOAZ01000025_gene2719	3.991e-77	268.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4182E@629295|Streptomyces griseus group	201174|Actinobacteria	M	Mur ligase family, catalytic domain	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2158c	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRD3_k127_5662970_0	1121877.JQKF01000014_gene30	1.539e-117	389.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4CMYF@84992|Acidimicrobiia	84992|Acidimicrobiia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRD3_k127_5679294_0	502025.Hoch_1969	5.21e-52	204.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MJD@68525|delta/epsilon subdivisions,2WJC4@28221|Deltaproteobacteria,2YXYZ@29|Myxococcales	28221|Deltaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	epsN	-	2.6.1.102	ko:K13010,ko:K19430	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SRD3_k127_5679294_2	370438.PTH_2769	3.643e-24	118.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,247M7@186801|Clostridia,260WC@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase family 4	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRD3_k127_5679294_3	351016.RAZWK3B_00105	7.016e-13	79.0	COG0454@1|root,COG0456@2|Bacteria,1NZN5@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD3_k127_5679294_1	649638.Trad_2723	5.113e-49	195.0	COG4424@1|root,COG4424@2|Bacteria	2|Bacteria	S	carbohydrate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
SRD3_k127_5679294_4	420662.Mpe_A0735	5.773e-06	59.0	COG1215@1|root,COG1215@2|Bacteria,1R66B@1224|Proteobacteria,2VXK9@28216|Betaproteobacteria,1KMH6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD3_k127_5682139_1	656024.FsymDg_0481	1.764e-133	437.0	COG1807@1|root,COG1807@2|Bacteria,2GJPU@201174|Actinobacteria,4EUST@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase, family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRD3_k127_5682139_2	1380386.JIAW01000013_gene2568	8.269e-88	297.0	COG1215@1|root,COG1215@2|Bacteria,2GJTE@201174|Actinobacteria,2338C@1762|Mycobacteriaceae	201174|Actinobacteria	M	glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
SRD3_k127_5682139_0	1123320.KB889689_gene530	8.523e-141	466.0	COG0318@1|root,COG0318@2|Bacteria,2GKZ6@201174|Actinobacteria	201174|Actinobacteria	IQ	synthetase	fadD17	GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0032787,GO:0042546,GO:0042759,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0072330,GO:1901576	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_5683535_2	710111.FraQA3DRAFT_5312	1.099e-64	231.0	COG1511@1|root,COG3605@1|root,COG5002@1|root,COG1511@2|Bacteria,COG3605@2|Bacteria,COG5002@2|Bacteria,2GKQX@201174|Actinobacteria,4EUER@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRD3_k127_5683535_3	208439.AJAP_18070	4.845e-41	160.0	COG1522@1|root,COG1522@2|Bacteria,2HVG9@201174|Actinobacteria,4E414@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRD3_k127_5683535_1	469371.Tbis_1027	2.515e-92	323.0	COG3186@1|root,COG3186@2|Bacteria,2GKCB@201174|Actinobacteria,4E9MH@85010|Pseudonocardiales	201174|Actinobacteria	E	Biopterin-dependent aromatic amino acid hydroxylase	phhA	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
SRD3_k127_5683535_0	1128421.JAGA01000002_gene634	4.737e-118	401.0	COG3185@1|root,COG3185@2|Bacteria	2|Bacteria	E	4-Hydroxyphenylpyruvate dioxygenase	hpd	GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.27,1.13.11.46	ko:K00457,ko:K16421	ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130	M00044	R01372,R02521,R06632	RC00505,RC00738,RC01471	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
SRD3_k127_5683535_4	2074.JNYD01000003_gene3481	8.774e-35	138.0	COG0179@1|root,COG0179@2|Bacteria,2GNGC@201174|Actinobacteria,4DZ90@85010|Pseudonocardiales	201174|Actinobacteria	Q	Fumarylacetoacetase	FAH	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
SRD3_k127_5685895_1	929712.KI912613_gene3514	1.731e-33	139.0	COG0438@1|root,COG0438@2|Bacteria,2HEVG@201174|Actinobacteria,4CSMZ@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRD3_k127_5685895_0	426117.M446_4024	3.31e-39	158.0	COG1215@1|root,COG1215@2|Bacteria,1PFWZ@1224|Proteobacteria,2V1PB@28211|Alphaproteobacteria,1JXDE@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD3_k127_5695332_0	479434.Sthe_2695	1.846e-66	243.0	COG5001@1|root,COG5001@2|Bacteria,2G7UT@200795|Chloroflexi,27Y1B@189775|Thermomicrobia	189775|Thermomicrobia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3
SRD3_k127_5695332_3	58123.JOFJ01000026_gene2761	6.614e-29	125.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria,4EJNW@85012|Streptosporangiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
SRD3_k127_5695332_2	526225.Gobs_1045	2.364e-31	133.0	COG1752@1|root,COG1752@2|Bacteria,2IB0F@201174|Actinobacteria,4ET56@85013|Frankiales	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRD3_k127_5704250_5	1313172.YM304_14260	5.792e-38	149.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4CNWS@84992|Acidimicrobiia	84992|Acidimicrobiia	L	endonuclease III	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRD3_k127_5704250_0	471852.Tcur_1579	3.973e-109	382.0	COG0596@1|root,COG0596@2|Bacteria,2HMX1@201174|Actinobacteria,4EHZ7@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	ephC	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRD3_k127_5704250_2	1313172.YM304_14700	1.202e-72	263.0	COG1235@1|root,COG1235@2|Bacteria,2IJCH@201174|Actinobacteria	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRD3_k127_5704250_4	1157635.KB892017_gene1647	9.616e-54	195.0	COG1853@1|root,COG1853@2|Bacteria,2GPJS@201174|Actinobacteria	201174|Actinobacteria	K	PFAM flavin reductase domain protein, FMN-binding	-	-	-	ko:K16048	ko00984,ko01100,map00984,map01100	-	R09819	RC00236	ko00000,ko00001,ko01000	-	-	-	Flavin_Reduct
SRD3_k127_5704250_3	1229780.BN381_10112	3.183e-70	249.0	COG1898@1|root,COG1898@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase activity	rfbC	-	1.1.1.133,4.2.1.46,5.1.3.13	ko:K00067,ko:K01710,ko:K01790	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R02777,R06513,R06514	RC00182,RC00402,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRD3_k127_5704250_1	1117379.BABA_14322	2.456e-75	255.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,1ZHB1@1386|Bacillus	91061|Bacilli	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_5719348_0	404589.Anae109_1442	5.843e-121	405.0	COG1032@1|root,COG1032@2|Bacteria,1Q3ZA@1224|Proteobacteria,439T3@68525|delta/epsilon subdivisions,2X567@28221|Deltaproteobacteria,2Z064@29|Myxococcales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRD3_k127_5719348_1	290397.Adeh_2440	0.0004857	43.0	COG0151@1|root,COG0151@2|Bacteria,1NA76@1224|Proteobacteria,43CA7@68525|delta/epsilon subdivisions,2X7KS@28221|Deltaproteobacteria,2Z204@29|Myxococcales	28221|Deltaproteobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
SRD3_k127_5751874_0	479434.Sthe_1092	0.0	1292.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,27XQK@189775|Thermomicrobia	189775|Thermomicrobia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
SRD3_k127_5751874_1	314278.NB231_16478	1.633e-238	758.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,1RYKS@1236|Gammaproteobacteria,1WX35@135613|Chromatiales	135613|Chromatiales	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
SRD3_k127_5751874_2	1246445.ANAY01000031_gene3578	3.653e-39	150.0	COG0673@1|root,COG0673@2|Bacteria,2GN2Z@201174|Actinobacteria,4EHEP@85012|Streptosporangiales	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	ydgJ	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRD3_k127_5782734_2	1121372.AULK01000003_gene307	1.424e-62	226.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2GKQ8@201174|Actinobacteria,4FMBE@85023|Microbacteriaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SRD3_k127_5782734_0	760568.Desku_1745	1.696e-73	262.0	COG0438@1|root,COG0438@2|Bacteria,1V5W1@1239|Firmicutes,24HV6@186801|Clostridia,263ZC@186807|Peptococcaceae	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRD3_k127_5782734_5	232721.Ajs_0187	2.022e-11	74.0	COG3774@1|root,COG3774@2|Bacteria,1R778@1224|Proteobacteria,2VXNG@28216|Betaproteobacteria,4AH9W@80864|Comamonadaceae	28216|Betaproteobacteria	M	Capsular polysaccharide synthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caps_synth,Gly_transf_sug
SRD3_k127_5782734_1	118173.KB235914_gene3846	3.751e-66	239.0	28M8R@1|root,2ZAMU@2|Bacteria,1G3XB@1117|Cyanobacteria,1HE2I@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5782734_3	1173026.Glo7428_1316	4.118e-53	208.0	COG0438@1|root,COG0438@2|Bacteria,1G0CV@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRD3_k127_5782734_4	886293.Sinac_0801	9.977e-25	114.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRD3_k127_5782734_6	1229780.BN381_50074	1.459e-10	64.0	COG0438@1|root,COG0438@2|Bacteria,2GK8D@201174|Actinobacteria,3UXFI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD3_k127_5789792_4	1229780.BN381_40071	6.352e-24	106.0	COG1625@1|root,COG1625@2|Bacteria,2H3RR@201174|Actinobacteria	201174|Actinobacteria	C	FeS-containing Cyanobacterial-specific oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
SRD3_k127_5789792_0	1313172.YM304_25520	1.149e-129	422.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CMP7@84992|Acidimicrobiia	84992|Acidimicrobiia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRD3_k127_5789792_2	502025.Hoch_1760	2.381e-59	216.0	COG4341@1|root,COG4341@2|Bacteria,1QHQD@1224|Proteobacteria	1224|Proteobacteria	S	Phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRD3_k127_5789792_1	1050202.KB913024_gene1976	2.557e-69	252.0	COG1215@1|root,COG1215@2|Bacteria,2I3M7@201174|Actinobacteria,409K1@622450|Actinopolysporales	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD3_k127_5789792_3	525909.Afer_1023	2.481e-25	111.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5798620_5	591159.ACEZ01000004_gene6651	2.346e-35	145.0	COG1670@1|root,COG1670@2|Bacteria,2GP87@201174|Actinobacteria	201174|Actinobacteria	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRD3_k127_5798620_1	743718.Isova_2485	2.206e-113	379.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4F3WI@85017|Promicromonosporaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD3_k127_5798620_3	1121877.JQKF01000018_gene2557	5.196e-51	203.0	COG1511@1|root,COG1511@2|Bacteria,2I6VG@201174|Actinobacteria,4CNCD@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5798620_2	1123023.JIAI01000003_gene2615	1.121e-79	276.0	COG1028@1|root,COG3320@1|root,COG1028@2|Bacteria,COG3320@2|Bacteria,2I2PV@201174|Actinobacteria,4DY9D@85010|Pseudonocardiales	201174|Actinobacteria	M	Male sterility protein	acrA1	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4,adh_short
SRD3_k127_5798620_0	1283299.AUKG01000002_gene4730	6.562e-153	513.0	COG0318@1|root,COG0318@2|Bacteria,2GKDF@201174|Actinobacteria,4CPC4@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_5798620_4	1229780.BN381_80199	2.581e-42	160.0	COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Fatty acid desaturase	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRD3_k127_5799357_1	67352.JODS01000033_gene7701	1.055e-28	121.0	COG3327@1|root,COG3327@2|Bacteria	2|Bacteria	K	negative regulation of DNA-templated transcription, initiation	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
SRD3_k127_5799357_0	1089544.KB912942_gene5787	1.724e-137	456.0	COG2015@1|root,COG2015@2|Bacteria,2H3T3@201174|Actinobacteria	201174|Actinobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
SRD3_k127_5809891_0	1313172.YM304_38400	1.323e-102	350.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	xdh	-	1.17.1.4,1.2.5.3,1.3.99.16	ko:K00087,ko:K03518,ko:K07302	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRD3_k127_5809891_2	1121877.JQKF01000018_gene2552	3.176e-42	169.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,4CN53@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Iron-sulphur cluster biosynthesis	erpA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRD3_k127_5809891_1	1313172.YM304_38460	5.131e-67	234.0	COG0489@1|root,COG2151@1|root,COG0489@2|Bacteria,COG2151@2|Bacteria,2H1YI@201174|Actinobacteria,4CNPI@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRD3_k127_5829940_0	1382356.JQMP01000004_gene583	1.416e-285	889.0	COG0365@1|root,COG0365@2|Bacteria,2G5KE@200795|Chloroflexi,27XEK@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRD3_k127_5829940_4	1123508.JH636454_gene5778	1.284e-17	93.0	COG2503@1|root,COG4639@1|root,COG2503@2|Bacteria,COG4639@2|Bacteria	2|Bacteria	Q	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
SRD3_k127_5829940_3	1313172.YM304_13200	1.361e-26	125.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRD3_k127_5829940_1	1048339.KB913029_gene3211	6.585e-87	298.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4ESG7@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_5829940_2	477641.MODMU_1643	2.759e-61	221.0	COG0815@1|root,COG0815@2|Bacteria,2GP5I@201174|Actinobacteria,4EX2Z@85013|Frankiales	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRD3_k127_5839898_3	469371.Tbis_2158	1.899e-25	108.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4DYMU@85010|Pseudonocardiales	201174|Actinobacteria	V	TIGRFAM daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRD3_k127_5839898_0	525909.Afer_1471	1.163e-201	632.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CNGH@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_5839898_2	469371.Tbis_1298	1.031e-94	329.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4DYFX@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRD3_k127_5839898_1	350058.Mvan_5928	5.972e-122	422.0	COG2114@1|root,COG2197@1|root,COG3903@1|root,COG2114@2|Bacteria,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae	201174|Actinobacteria	K	involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Guanylate_cyc,NB-ARC
SRD3_k127_5842368_12	446465.Bfae_02640	2.068e-07	60.0	COG1652@1|root,COG1652@2|Bacteria,2GK68@201174|Actinobacteria,4FBDH@85020|Dermabacteraceae	201174|Actinobacteria	M	Transglycosylase-like domain	-	-	-	ko:K21687	-	-	-	-	ko00000	-	GH23	-	LysM,Peptidase_M23,Transglycosylas
SRD3_k127_5842368_5	404589.Anae109_0594	1.163e-75	275.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,42VPN@68525|delta/epsilon subdivisions,2WRK6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRD3_k127_5842368_7	1449069.JMLO01000002_gene4752	7.22e-48	188.0	COG0596@1|root,COG0596@2|Bacteria,2I8WB@201174|Actinobacteria,4G0AW@85025|Nocardiaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRD3_k127_5842368_1	1386089.N865_16800	2.387e-142	469.0	COG0438@1|root,COG0438@2|Bacteria,2ICGI@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1,YHS
SRD3_k127_5842368_10	43354.JOIJ01000002_gene4202	6.278e-13	79.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4E2RP@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRD3_k127_5842368_2	1313172.YM304_28170	1.438e-111	370.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4CMXH@84992|Acidimicrobiia	84992|Acidimicrobiia	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRD3_k127_5842368_0	448385.sce7660	3.112e-231	730.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,2YU3K@29|Myxococcales	28221|Deltaproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRD3_k127_5842368_6	1370121.AUWS01000002_gene1037	4.754e-49	190.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,23565@1762|Mycobacteriaceae	201174|Actinobacteria	E	PFAM Alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_5842368_8	9733.XP_004267242.1	4.071e-27	120.0	COG1028@1|root,KOG1205@2759|Eukaryota,38BER@33154|Opisthokonta,3BG9W@33208|Metazoa,3CVRW@33213|Bilateria,47ZPF@7711|Chordata,497UB@7742|Vertebrata,3J4WV@40674|Mammalia,4J9GG@91561|Cetartiodactyla	33208|Metazoa	Q	Dehydrogenase reductase (SDR family) member 7B	DHRS7B	GO:0000140,GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0003674,GO:0003824,GO:0006629,GO:0006662,GO:0007275,GO:0008150,GO:0008152,GO:0008610,GO:0008611,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018904,GO:0030097,GO:0030099,GO:0030154,GO:0030223,GO:0030851,GO:0032501,GO:0032502,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046485,GO:0046504,GO:0048513,GO:0048534,GO:0048731,GO:0048856,GO:0048869,GO:0055114,GO:0071704,GO:0097384,GO:1901503,GO:1901576	-	ko:K11166	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
SRD3_k127_5842368_3	235985.BBPN01000009_gene3759	8.664e-100	345.0	COG1290@1|root,COG1290@2|Bacteria,2GK58@201174|Actinobacteria,2NI2H@228398|Streptacidiphilus	201174|Actinobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_N_2
SRD3_k127_5842368_4	525909.Afer_1523	6.189e-89	302.0	COG1290@1|root,COG1290@2|Bacteria,2GK58@201174|Actinobacteria,4CNNI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5842368_11	1463887.KL590044_gene8319	3.247e-12	70.0	COG1290@1|root,COG1290@2|Bacteria,2GTS3@201174|Actinobacteria	201174|Actinobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_5842368_9	1463887.KL590036_gene3622	8.308e-17	82.0	COG1141@1|root,COG1141@2|Bacteria,2GSJ7@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_15
SRD3_k127_5843431_3	1306406.ASHX01000001_gene4159	3.321e-98	327.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRD3_k127_5843431_2	1146883.BLASA_1744	1.564e-111	369.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,4ETZ3@85013|Frankiales	201174|Actinobacteria	L	Ku70 and Ku80 are 70kDa and 80kDa subunits of the Lupus Ku autoantigen	-	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRD3_k127_5843431_1	66897.DJ64_21985	3.704e-135	437.0	COG1387@1|root,COG1387@2|Bacteria,2GMFH@201174|Actinobacteria	201174|Actinobacteria	E	PHP domain	polX	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_8,PHP
SRD3_k127_5843431_0	1242864.D187_001075	1.395e-145	473.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,430G4@68525|delta/epsilon subdivisions,2WVMP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_585789_1	525909.Afer_0370	6.316e-112	398.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,4CMTV@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRD3_k127_585789_0	1229780.BN381_160007	4.275e-171	562.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria,3UWBF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRD3_k127_5869575_1	1122604.JONR01000045_gene2508	5.757e-110	370.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RPIE@1236|Gammaproteobacteria,1X4MD@135614|Xanthomonadales	135614|Xanthomonadales	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRD3_k127_5869575_3	1229780.BN381_80217	1.07e-71	252.0	COG1946@1|root,COG1946@2|Bacteria	2|Bacteria	I	acyl-CoA hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRD3_k127_5869575_4	196162.Noca_3341	2.187e-54	218.0	COG1832@1|root,COG1832@2|Bacteria,2IJYY@201174|Actinobacteria	201174|Actinobacteria	S	PFAM CoA-binding domain protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRD3_k127_5869575_0	298655.KI912266_gene5798	4.416e-246	769.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ERZH@85013|Frankiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_5869575_2	1123320.KB889684_gene2300	4.539e-100	329.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA12	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD3_k127_5880260_1	1122609.AUGT01000020_gene987	2.409e-13	81.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4DNY6@85009|Propionibacteriales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRD3_k127_5880260_0	1120960.ATXG01000015_gene1622	3.44e-32	143.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,4FP2D@85023|Microbacteriaceae	201174|Actinobacteria	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRD3_k127_5904232_1	1313172.YM304_02490	5.938e-104	349.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4CN0G@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
SRD3_k127_5904232_3	749927.AMED_3083	1.531e-57	214.0	COG1691@1|root,COG1691@2|Bacteria,2IAKU@201174|Actinobacteria,4E2XT@85010|Pseudonocardiales	201174|Actinobacteria	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRD3_k127_5904232_2	1463856.JOHY01000088_gene2417	1.67e-86	310.0	COG1641@1|root,COG1641@2|Bacteria,2I8J1@201174|Actinobacteria	201174|Actinobacteria	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRD3_k127_5904232_0	1123320.KB889686_gene602	9.443e-197	622.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria	201174|Actinobacteria	E	decarboxylase	ddc	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRD3_k127_5904232_4	365528.KB891103_gene3963	2.478e-21	110.0	COG0577@1|root,COG0577@2|Bacteria,2GWZR@201174|Actinobacteria,4EVD8@85013|Frankiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRD3_k127_5985501_1	298654.FraEuI1c_6904	4.636e-102	346.0	COG0707@1|root,COG0707@2|Bacteria,2GREI@201174|Actinobacteria,4EWT3@85013|Frankiales	201174|Actinobacteria	M	Monogalactosyldiacylglycerol (MGDG) synthase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,Glyco_tran_28_C,Glyco_trans_1_4,MGDG_synth,WES_acyltransf
SRD3_k127_5985501_0	1380394.JADL01000005_gene5573	2.698e-224	722.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,2TRFJ@28211|Alphaproteobacteria,2JRB5@204441|Rhodospirillales	204441|Rhodospirillales	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRD3_k127_5985501_2	1120934.KB894403_gene398	1.579e-20	97.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	pat	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRD3_k127_5989997_1	298654.FraEuI1c_1929	2.402e-179	572.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	aldA_1	-	1.2.1.3,1.2.1.39	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD3_k127_5989997_0	392499.Swit_2087	2.413e-186	604.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TR1E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRD3_k127_5989997_3	298655.KI912266_gene5570	1.028e-105	356.0	COG1878@1|root,COG1878@2|Bacteria,2GJ59@201174|Actinobacteria,4EVXM@85013|Frankiales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRD3_k127_5989997_4	298655.KI912266_gene5601	8.118e-51	193.0	COG1309@1|root,COG1309@2|Bacteria,2GK0V@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD3_k127_5989997_5	1229780.BN381_130223	6.183e-39	152.0	COG1309@1|root,COG1309@2|Bacteria,2GMPD@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K22107	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRD3_k127_5989997_2	479433.Caci_5895	6.854e-143	464.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_5995549_2	1229780.BN381_350085	1.216e-17	98.0	COG1960@1|root,COG1960@2|Bacteria,2GKUW@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRD3_k127_5995549_0	471852.Tcur_4613	1.496e-167	535.0	COG1960@1|root,COG1960@2|Bacteria,2GJA9@201174|Actinobacteria,4EIAG@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	fadE20	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_5995549_1	525909.Afer_0085	1.344e-137	446.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CMTJ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRD3_k127_5997635_4	1123023.JIAI01000001_gene6257	1.055e-125	413.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4E1ZB@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRD3_k127_5997635_7	525909.Afer_1990	3.057e-98	340.0	COG0265@1|root,COG1286@1|root,COG0265@2|Bacteria,COG1286@2|Bacteria,2GJ92@201174|Actinobacteria,4CNDB@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRD3_k127_5997635_0	649831.L083_2761	1.518e-243	768.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4D8XJ@85008|Micromonosporales	201174|Actinobacteria	G	Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRD3_k127_5997635_2	1463921.JODF01000074_gene367	4.649e-142	470.0	COG1063@1|root,COG1063@2|Bacteria,2GKFG@201174|Actinobacteria	201174|Actinobacteria	E	Alcohol dehydrogenase GroES domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,Glu_dehyd_C
SRD3_k127_5997635_5	525909.Afer_1991	4.001e-113	372.0	COG0491@1|root,COG0491@2|Bacteria,2I9GW@201174|Actinobacteria,4CNHS@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRD3_k127_5997635_16	1429046.RR21198_4549	1.046e-13	78.0	COG3794@1|root,COG3794@2|Bacteria,2H73G@201174|Actinobacteria,4G36P@85025|Nocardiaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRD3_k127_5997635_15	1288484.APCS01000005_gene1196	4.38e-15	86.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4
SRD3_k127_5997635_13	1463900.JOIX01000041_gene1975	1.543e-21	100.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRD3_k127_5997635_6	446466.Cfla_1198	1.197e-98	328.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria,4F0PC@85016|Cellulomonadaceae	201174|Actinobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
SRD3_k127_5997635_12	1041522.MCOL_V217038	6.217e-41	174.0	COG2030@1|root,COG2030@2|Bacteria,2IHT0@201174|Actinobacteria,2392X@1762|Mycobacteriaceae	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRD3_k127_5997635_10	44454.NF84_05950	1.917e-63	223.0	COG2030@1|root,COG2030@2|Bacteria,2GN7T@201174|Actinobacteria,235VM@1762|Mycobacteriaceae	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRD3_k127_5997635_8	247634.GPB2148_2610	4.965e-86	293.0	COG4221@1|root,COG4221@2|Bacteria,1MVYG@1224|Proteobacteria,1S013@1236|Gammaproteobacteria,1J5C8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_5997635_1	67257.JODR01000012_gene6018	1.143e-143	479.0	COG2159@1|root,COG2159@2|Bacteria,2GP2D@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRD3_k127_5997635_11	190650.CC_3495	1.147e-51	195.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,2KIJ7@204458|Caulobacterales	204458|Caulobacterales	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
SRD3_k127_5997635_3	479433.Caci_2288	9.15e-128	426.0	COG2159@1|root,COG2159@2|Bacteria,2HG7W@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRD3_k127_5997635_14	298655.KI912267_gene7626	1.858e-20	96.0	COG4689@1|root,COG4689@2|Bacteria,2I8M2@201174|Actinobacteria	201174|Actinobacteria	Q	acetoacetate decarboxylase	-	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
SRD3_k127_5997635_9	1313172.YM304_38610	1.629e-73	252.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CNQN@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRD3_k127_6003256_0	1229780.BN381_400026	7.592e-218	687.0	COG1351@1|root,COG1351@2|Bacteria,2HBYZ@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRD3_k127_6003256_1	928724.SacglDRAFT_02447	5.289e-154	510.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,4DXSA@85010|Pseudonocardiales	201174|Actinobacteria	L	DEAD DEAH box helicase	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
SRD3_k127_6003256_2	525909.Afer_0917	2.87e-69	247.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4CN3F@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRD3_k127_6003256_4	743974.MBO_08721	0.0003329	49.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,3NPHJ@468|Moraxellaceae	1236|Gammaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRD3_k127_6003256_3	1121877.JQKF01000002_gene1624	5.152e-41	158.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4CNAZ@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRD3_k127_6026346_0	1121877.JQKF01000002_gene1674	1.812e-278	874.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CMVH@84992|Acidimicrobiia	84992|Acidimicrobiia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRD3_k127_6028920_0	1313172.YM304_19760	7.965e-70	246.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,4CN56@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
SRD3_k127_6037302_3	679197.HMPREF9336_01018	3.091e-87	305.0	COG2239@1|root,COG2239@2|Bacteria,2GMMK@201174|Actinobacteria	201174|Actinobacteria	P	transporter mgtE	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
SRD3_k127_6037302_0	1111479.AXAR01000008_gene2292	1.335e-199	636.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HE2B@91061|Bacilli	91061|Bacilli	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
SRD3_k127_6037302_7	67315.JOBD01000008_gene3677	3.813e-38	164.0	COG0726@1|root,COG0726@2|Bacteria,2GMC2@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRD3_k127_6037302_2	479433.Caci_6343	1.605e-110	378.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRD3_k127_6037302_10	298655.KI912266_gene1059	5.336e-25	109.0	COG1846@1|root,COG1846@2|Bacteria,2IFQ9@201174|Actinobacteria,4ET3M@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRD3_k127_6037302_9	525909.Afer_1492	4.806e-26	119.0	COG0694@1|root,COG0694@2|Bacteria,2HGE4@201174|Actinobacteria,4CNCF@84992|Acidimicrobiia	84992|Acidimicrobiia	O	NifU-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU
SRD3_k127_6037302_4	1229780.BN381_20081	5.49e-69	250.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
SRD3_k127_6037302_1	525909.Afer_1086	5.311e-111	384.0	COG0332@1|root,COG0332@2|Bacteria,2GJP8@201174|Actinobacteria,4CMQV@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRD3_k127_6037302_6	1378168.N510_00532	3.221e-38	160.0	COG1208@1|root,COG1208@2|Bacteria,1UIRX@1239|Firmicutes	1239|Firmicutes	JM	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
SRD3_k127_6037302_5	298653.Franean1_2440	1.879e-66	238.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4EVV0@85013|Frankiales	201174|Actinobacteria	P	Cation efflux family	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRD3_k127_6037302_11	1121952.ATXT01000014_gene1395	9.71e-21	95.0	COG1254@1|root,COG1254@2|Bacteria,2HZJD@201174|Actinobacteria,4FQ1C@85023|Microbacteriaceae	201174|Actinobacteria	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRD3_k127_6037302_8	591158.SSMG_03097	2.357e-27	119.0	COG5592@1|root,COG5592@2|Bacteria,2HF5Y@201174|Actinobacteria	201174|Actinobacteria	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRD3_k127_6049526_0	369723.Strop_3120	2.326e-95	318.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria,4DBSR@85008|Micromonosporales	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	agpS	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRD3_k127_6049526_1	66373.JOFQ01000005_gene3638	1.517e-74	268.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria	201174|Actinobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
SRD3_k127_6057764_0	1313172.YM304_07620	1.911e-236	752.0	COG4867@1|root,COG4867@2|Bacteria,2H14W@201174|Actinobacteria,4CMU5@84992|Acidimicrobiia	84992|Acidimicrobiia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6057764_2	1313172.YM304_07520	1.98e-193	614.0	COG1239@1|root,COG1239@2|Bacteria,2GMRS@201174|Actinobacteria,4CMSG@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Mg-chelatase subunit ChlI	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
SRD3_k127_6057764_3	479433.Caci_0748	3.877e-90	306.0	2CEY7@1|root,2Z8CG@2|Bacteria,2GKI0@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6057764_1	351607.Acel_1865	9.885e-200	640.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4ES69@85013|Frankiales	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRD3_k127_605878_1	1229780.BN381_110049	1.284e-101	337.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,3UW8P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRD3_k127_605878_2	1313172.YM304_03920	1.483e-81	303.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4CMZ7@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Polyprenyl synthetase	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRD3_k127_605878_0	1120950.KB892801_gene1744	3.132e-250	808.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4DPBH@85009|Propionibacteriales	201174|Actinobacteria	O	C-terminal, D2-small domain, of ClpB protein	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRD3_k127_6082318_2	525909.Afer_1840	9.177e-17	90.0	COG1135@1|root,COG1135@2|Bacteria,2HH1B@201174|Actinobacteria,4CP1I@84992|Acidimicrobiia	84992|Acidimicrobiia	P	NIL	-	-	-	-	-	-	-	-	-	-	-	-	NIL
SRD3_k127_6082318_1	28444.JODQ01000010_gene3087	1.241e-74	259.0	COG1606@1|root,COG1606@2|Bacteria,2GPA1@201174|Actinobacteria	201174|Actinobacteria	S	PFAM ExsB family protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase,QueC
SRD3_k127_6082318_0	1229780.BN381_150097	3.263e-82	280.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	ywfI	-	-	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11522	RC00884	ko00000,ko00001,ko01000	-	-	-	Chlor_dismutase
SRD3_k127_6107822_1	1313172.YM304_10650	9.298e-27	113.0	COG0224@1|root,COG3743@1|root,COG0224@2|Bacteria,COG3743@2|Bacteria,2GJ7Q@201174|Actinobacteria,4CN1H@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRD3_k127_6107822_0	525909.Afer_1795	3.402e-244	762.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4CMWB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRD3_k127_6107822_2	457425.XNR_1460	1.936e-13	78.0	COG0355@1|root,COG0355@2|Bacteria,2IHNZ@201174|Actinobacteria	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
SRD3_k127_6107822_3	981369.JQMJ01000004_gene4807	0.0002841	48.0	COG0500@1|root,COG2226@2|Bacteria,2GM9H@201174|Actinobacteria,2NKWW@228398|Streptacidiphilus	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23
SRD3_k127_6125397_2	1034345.CAEM01000018_gene335	5.033e-102	338.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CV1T@84998|Coriobacteriia	84998|Coriobacteriia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD3_k127_6125397_3	390989.JOEG01000030_gene1732	4.062e-70	243.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4DEXB@85008|Micromonosporales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRD3_k127_6125397_4	1150599.MPHLEI_08209	1.477e-69	248.0	COG0451@1|root,COG0451@2|Bacteria,2I9DG@201174|Actinobacteria,237C3@1762|Mycobacteriaceae	201174|Actinobacteria	GM	NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRD3_k127_6125397_0	1341646.CBMO010000080_gene321	1.282e-145	481.0	COG3804@1|root,COG3804@2|Bacteria,2IBKQ@201174|Actinobacteria,2375W@1762|Mycobacteriaceae	201174|Actinobacteria	S	dihydrodipicolinate reductase	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
SRD3_k127_6125397_1	298654.FraEuI1c_0210	3.965e-132	447.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4ERP1@85013|Frankiales	201174|Actinobacteria	S	PFAM MMPL domain protein	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRD3_k127_6125397_6	1451261.AS96_13645	7.941e-06	57.0	2DPV0@1|root,333GV@2|Bacteria,2GU7A@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_617114_2	1313172.YM304_38880	3.583e-50	198.0	COG0461@1|root,COG0461@2|Bacteria,2HG8J@201174|Actinobacteria,4CN64@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRD3_k127_617114_1	1121272.KB903261_gene6018	1.306e-94	322.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4DASB@85008|Micromonosporales	201174|Actinobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRD3_k127_617114_0	1240349.ANGC01000011_gene342	1.164e-143	473.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4FU3Z@85025|Nocardiaceae	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRD3_k127_617114_3	743718.Isova_0820	0.0004221	50.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4F3V0@85017|Promicromonosporaceae	201174|Actinobacteria	S	PHP domain	PPA1328	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
SRD3_k127_6206253_3	1229780.BN381_80127	6.259e-93	308.0	COG1028@1|root,COG1028@2|Bacteria,2GK47@201174|Actinobacteria,3UXC4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	KR domain	rhlG	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRD3_k127_6206253_2	269800.Tfu_0980	2.731e-144	466.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4EGFJ@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_6206253_1	710687.KI912270_gene1358	1.734e-148	485.0	COG2130@1|root,COG2130@2|Bacteria,2GKR8@201174|Actinobacteria,232K1@1762|Mycobacteriaceae	201174|Actinobacteria	S	NADP-dependent oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
SRD3_k127_6206253_5	487521.OCU_21340	4.94e-35	153.0	290Z6@1|root,2ZNKX@2|Bacteria,2I9VD@201174|Actinobacteria,236P3@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6206253_4	1449346.JQMO01000003_gene2417	2.743e-85	300.0	COG1520@1|root,COG1520@2|Bacteria,2I9FJ@201174|Actinobacteria	201174|Actinobacteria	M	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRD3_k127_6206253_0	266779.Meso_3357	1.181e-195	632.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,43H3G@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRD3_k127_6206875_0	525909.Afer_0721	1.024e-92	319.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CN3Q@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRD3_k127_6206875_1	1206720.BAFQ01000109_gene2696	1.471e-84	291.0	COG2120@1|root,COG2120@2|Bacteria,2GIUS@201174|Actinobacteria,4FY27@85025|Nocardiaceae	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	rifO	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRD3_k127_6206875_2	1122247.C731_1963	3.865e-15	81.0	COG2050@1|root,COG2050@2|Bacteria,2GK27@201174|Actinobacteria,238AP@1762|Mycobacteriaceae	201174|Actinobacteria	Q	protein, possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRD3_k127_6207128_1	1229780.BN381_100028	4.679e-123	404.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
SRD3_k127_6207128_3	1229780.BN381_360021	3.885e-94	323.0	COG1073@1|root,COG1073@2|Bacteria,2I8SP@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6207128_0	1133849.O3I_010110	1.241e-158	513.0	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria,4FV06@85025|Nocardiaceae	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	-	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRD3_k127_6207128_2	1299327.I546_6086	6.306e-123	410.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,237RH@1762|Mycobacteriaceae	201174|Actinobacteria	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRD3_k127_6207128_7	463191.SSEG_10496	2.532e-32	131.0	COG0655@1|root,COG0655@2|Bacteria,2II43@201174|Actinobacteria	201174|Actinobacteria	S	Multimeric flavodoxin WrbA	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRD3_k127_6207128_5	1463858.JOHR01000001_gene6186	1.369e-83	309.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria	2|Bacteria	E	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C
SRD3_k127_6207128_8	797209.ZOD2009_19948	1.513e-30	138.0	COG1404@1|root,arCOG00702@2157|Archaea,2XSZR@28890|Euryarchaeota,23U34@183963|Halobacteria	183963|Halobacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.62	ko:K01342,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
SRD3_k127_6207128_4	710111.FraQA3DRAFT_0719	1.282e-93	317.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4ERCS@85013|Frankiales	201174|Actinobacteria	L	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRD3_k127_6207128_6	1313172.YM304_24850	4.734e-52	197.0	COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria,4CN5Z@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
SRD3_k127_6207128_9	219305.MCAG_04950	7.327e-05	51.0	COG3937@1|root,COG3937@2|Bacteria,2ISFA@201174|Actinobacteria,4DEZR@85008|Micromonosporales	201174|Actinobacteria	S	granule-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
SRD3_k127_6250540_2	557599.MKAN_18950	5.858e-40	151.0	COG3687@1|root,COG3687@2|Bacteria,2IBIP@201174|Actinobacteria,234AF@1762|Mycobacteriaceae	201174|Actinobacteria	S	Predicted metal-dependent hydrolase	-	-	-	ko:K07044	-	-	-	-	ko00000	-	-	-	Metal_hydrol
SRD3_k127_6250540_1	487521.OCU_40940	2.166e-76	280.0	COG0581@1|root,COG0581@2|Bacteria,2H3XE@201174|Actinobacteria,23D51@1762|Mycobacteriaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	pstA2	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRD3_k127_6250540_0	487521.OCU_40930	6.314e-114	376.0	COG0573@1|root,COG0573@2|Bacteria,2ISS5@201174|Actinobacteria,23CM1@1762|Mycobacteriaceae	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRD3_k127_6276305_1	1157632.AQWQ01000009_gene2831	6.862e-61	219.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria	201174|Actinobacteria	E	Glycine oxidase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
SRD3_k127_6276305_0	196162.Noca_3022	1.441e-202	653.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2GN09@201174|Actinobacteria,4DP8G@85009|Propionibacteriales	201174|Actinobacteria	E	GXGXG motif	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRD3_k127_6281774_6	867903.ThesuDRAFT_02096	8.105e-15	75.0	COG0693@1|root,COG0693@2|Bacteria,1V1CG@1239|Firmicutes,25CHN@186801|Clostridia,3WD9C@538999|Clostridiales incertae sedis	186801|Clostridia	S	TIGRFAM intracellular protease, PfpI family	pfpI	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRD3_k127_6281774_0	926560.KE387023_gene1738	8.81e-90	300.0	COG4122@1|root,COG4122@2|Bacteria,1WKHV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
SRD3_k127_6281774_2	1429046.RR21198_0066	3.518e-71	249.0	COG0637@1|root,COG0637@2|Bacteria,2I362@201174|Actinobacteria,4FYI5@85025|Nocardiaceae	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRD3_k127_6281774_4	136273.GY22_14975	2.238e-17	93.0	2DRQB@1|root,33CKR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6281774_5	1121943.KB899991_gene2432	1.156e-15	88.0	COG1846@1|root,COG1846@2|Bacteria,1RFUJ@1224|Proteobacteria,1S8JQ@1236|Gammaproteobacteria,1XKUY@135619|Oceanospirillales	135619|Oceanospirillales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRD3_k127_6281774_1	1121877.JQKF01000018_gene2563	7.208e-78	280.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CMST@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRD3_k127_6281774_3	1077972.ARGLB_047_01190	2.019e-40	157.0	29JD5@1|root,306AN@2|Bacteria,2I9J8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6283338_0	1048339.KB913029_gene1969	4.779e-183	610.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2H3P9@201174|Actinobacteria,4EXEI@85013|Frankiales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRD3_k127_6308292_1	1122138.AQUZ01000046_gene367	3.496e-11	75.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria	201174|Actinobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRD3_k127_6308292_0	1123065.ATWL01000018_gene2118	2.06e-59	233.0	COG3857@1|root,COG3857@2|Bacteria,2I6QC@201174|Actinobacteria	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRD3_k127_6338766_3	1380390.JIAT01000012_gene3163	9.532e-107	355.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4CRJZ@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K12429	-	-	-	-	ko00000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_6338766_12	298653.Franean1_5137	1.035e-25	114.0	COG1324@1|root,COG1324@2|Bacteria,2IQF1@201174|Actinobacteria	201174|Actinobacteria	P	Divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRD3_k127_6338766_11	309801.trd_A0619	6.302e-30	121.0	COG4274@1|root,COG4274@2|Bacteria,2GBAJ@200795|Chloroflexi,27YIF@189775|Thermomicrobia	189775|Thermomicrobia	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRD3_k127_6338766_7	1229780.BN381_80160	1.124e-55	216.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,3UWTI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRD3_k127_6338766_1	1229780.BN381_250066	2.25e-161	522.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_6338766_10	1160718.SU9_32243	5.667e-34	142.0	COG0697@1|root,COG0697@2|Bacteria,2GRXH@201174|Actinobacteria	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Mg_trans_NIPA
SRD3_k127_6338766_2	1123354.AUDR01000012_gene1823	1.504e-117	401.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2VIZ7@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.2,1.4.1.3	ko:K00260,ko:K00261	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRD3_k127_6338766_4	1229780.BN381_210088	2.972e-89	298.0	COG0491@1|root,COG0491@2|Bacteria,2GKJA@201174|Actinobacteria,3UXGK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRD3_k127_6338766_0	67373.JOBF01000012_gene4007	8.04e-168	535.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_6338766_14	469371.Tbis_0587	1.839e-12	70.0	COG1008@1|root,COG1008@2|Bacteria,2GR9E@201174|Actinobacteria,4E6TJ@85010|Pseudonocardiales	201174|Actinobacteria	C	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707
SRD3_k127_6338766_8	1313172.YM304_30260	4.833e-53	196.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ycjY	GO:0008150,GO:0009987,GO:0051301	-	ko:K01990,ko:K06889	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	DLH,Hydrolase_4,Peptidase_S15
SRD3_k127_6338766_6	525909.Afer_0711	4.645e-57	207.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria	201174|Actinobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0414c	TMP-TENI
SRD3_k127_6338766_5	29306.JOBE01000003_gene4133	1.561e-69	250.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria	201174|Actinobacteria	L	PFAM HhH-GPD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRD3_k127_6338766_9	1121272.KB903290_gene4487	6.026e-52	186.0	COG0346@1|root,COG0346@2|Bacteria,2GQZ9@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD3_k127_6378931_0	1229780.BN381_150069	8.426e-272	847.0	COG2185@1|root,COG2185@2|Bacteria,2I2N3@201174|Actinobacteria,3UX6U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	B12 binding domain	meaA	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRD3_k127_6378931_1	1229780.BN381_100132	8.337e-111	382.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,3UX97@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRD3_k127_6378931_2	471852.Tcur_1562	8.761e-86	292.0	COG4221@1|root,COG4221@2|Bacteria,2GN3I@201174|Actinobacteria,4EI20@85012|Streptosporangiales	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_6378931_4	1229780.BN381_100131	2.284e-48	182.0	COG4242@1|root,COG4242@2|Bacteria	2|Bacteria	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRD3_k127_6378931_3	1229780.BN381_50060	1.104e-74	255.0	COG0652@1|root,COG0652@2|Bacteria,2GN8G@201174|Actinobacteria,3UWKX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
SRD3_k127_6378931_5	1313172.YM304_36860	2.159e-40	160.0	COG0652@1|root,COG0652@2|Bacteria,2GN8G@201174|Actinobacteria,4CN2J@84992|Acidimicrobiia	84992|Acidimicrobiia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRD3_k127_6378931_6	1453503.AU05_18660	6.313e-08	62.0	COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,1RYNH@1236|Gammaproteobacteria,1YDZH@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRD3_k127_6412170_5	981369.JQMJ01000004_gene3841	4.684e-76	263.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.19	ko:K00137	ko00330,ko00410,ko01100,map00330,map00410,map01100	-	R02549	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRD3_k127_6412170_3	290340.AAur_0342	6.632e-111	367.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,1W8QY@1268|Micrococcaceae	201174|Actinobacteria	S	alcohol dehydrogenase	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_6412170_10	1385521.N803_06915	6.474e-20	93.0	COG1872@1|root,COG1872@2|Bacteria,2GQSC@201174|Actinobacteria	201174|Actinobacteria	EGP	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRD3_k127_6412170_9	266940.Krad_4498	9.314e-28	129.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRD3_k127_6412170_2	656024.FsymDg_3106	1.218e-117	415.0	COG0277@1|root,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4ESN2@85013|Frankiales	201174|Actinobacteria	C	PFAM FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SRD3_k127_6412170_0	644283.Micau_5368	9.506e-166	544.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,2GITG@201174|Actinobacteria,4DBEK@85008|Micromonosporales	201174|Actinobacteria	K	AlkA N-terminal domain	alkA	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
SRD3_k127_6412170_7	269800.Tfu_0366	2.365e-39	162.0	COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria,4EJA2@85012|Streptosporangiales	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
SRD3_k127_6412170_6	222534.KB893672_gene2971	4.833e-72	252.0	COG0500@1|root,COG0500@2|Bacteria,2GX4K@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRD3_k127_6412170_8	1121017.AUFG01000005_gene1031	4.71e-30	130.0	2CFVG@1|root,3346Y@2|Bacteria,2GRCI@201174|Actinobacteria,4FHMV@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
SRD3_k127_6412170_11	637390.AFOH01000081_gene2585	0.0006705	49.0	COG2755@1|root,COG2755@2|Bacteria,1QD06@1224|Proteobacteria,1T8UR@1236|Gammaproteobacteria,2NDG5@225057|Acidithiobacillales	225057|Acidithiobacillales	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6412170_4	404589.Anae109_0474	3.188e-80	279.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,43A9Z@68525|delta/epsilon subdivisions,2X37W@28221|Deltaproteobacteria,2YV2G@29|Myxococcales	28221|Deltaproteobacteria	S	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate	tam	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
SRD3_k127_6412170_1	345341.KUTG_00976	7.33e-139	474.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DYN9@85010|Pseudonocardiales	201174|Actinobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
SRD3_k127_6421682_1	1229780.BN381_170007	1.13e-59	213.0	COG0247@1|root,COG0247@2|Bacteria,2GVNV@201174|Actinobacteria	201174|Actinobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
SRD3_k127_6421682_2	1313172.YM304_19060	3.83e-20	99.0	2CC1Y@1|root,32YV9@2|Bacteria	2|Bacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRD3_k127_6421682_3	2074.JNYD01000013_gene6818	2.356e-06	60.0	COG0477@1|root,COG2814@2|Bacteria,2GM2G@201174|Actinobacteria,4DYSB@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Uncharacterised MFS-type transporter YbfB	pcaK	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_4,Sugar_tr
SRD3_k127_6421682_0	1229780.BN381_80401	1.264e-66	233.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,3UW79@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRD3_k127_6429876_1	1313172.YM304_18430	3.516e-48	194.0	COG5011@1|root,COG5011@2|Bacteria,2GIS7@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
SRD3_k127_6429876_0	1313172.YM304_18420	1.599e-294	916.0	COG1032@1|root,COG1032@2|Bacteria,2GJY1@201174|Actinobacteria	201174|Actinobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRD3_k127_6434186_2	710696.Intca_2630	5.457e-59	226.0	COG0438@1|root,COG0438@2|Bacteria,2GNIU@201174|Actinobacteria,4FFTW@85021|Intrasporangiaceae	201174|Actinobacteria	M	galactosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRD3_k127_6434186_1	1385519.N801_07500	4.62e-75	269.0	COG0438@1|root,COG0438@2|Bacteria,2GNR8@201174|Actinobacteria,4FG91@85021|Intrasporangiaceae	201174|Actinobacteria	M	Lipopolysaccharide biosynthesis protein	-	-	-	ko:K19424	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRD3_k127_6434186_4	351607.Acel_0420	1.377e-26	121.0	COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4ESU0@85013|Frankiales	201174|Actinobacteria	GM	Transport permease protein	wzm	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRD3_k127_6434186_0	67352.JODS01000028_gene2338	5.616e-125	411.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria	201174|Actinobacteria	GM	ABC transporter	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRD3_k127_6434186_6	866536.Belba_2526	9.654e-06	59.0	COG1216@1|root,COG1216@2|Bacteria,4NTV3@976|Bacteroidetes	976|Bacteroidetes	S	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD3_k127_6434186_5	411154.GFO_2030	1.014e-17	99.0	COG1216@1|root,COG1216@2|Bacteria,4NUYP@976|Bacteroidetes,1I638@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD3_k127_6434186_3	649638.Trad_2723	6.806e-53	194.0	COG4424@1|root,COG4424@2|Bacteria	2|Bacteria	S	carbohydrate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
SRD3_k127_643750_0	1313172.YM304_27060	6.423e-160	509.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CMRW@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRD3_k127_643750_6	68199.JNZO01000015_gene3481	5.968e-07	56.0	COG3462@1|root,COG3462@2|Bacteria,2GRGM@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
SRD3_k127_643750_5	1048339.KB913029_gene2153	3.449e-17	90.0	COG1514@1|root,COG1514@2|Bacteria,2GNDN@201174|Actinobacteria,4ETCC@85013|Frankiales	201174|Actinobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRD3_k127_643750_2	1313172.YM304_05900	2.287e-57	208.0	COG2110@1|root,COG2110@2|Bacteria,2IFEC@201174|Actinobacteria	201174|Actinobacteria	S	domain protein	lppD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Macro
SRD3_k127_643750_1	1469245.JFBG01000054_gene2100	4.003e-140	460.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1T236@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRD3_k127_643750_4	525909.Afer_0651	3.47e-32	137.0	COG0558@1|root,COG0558@2|Bacteria,2HGCB@201174|Actinobacteria,4CNAE@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRD3_k127_643750_3	1313172.YM304_16500	3.133e-48	177.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CMWG@84992|Acidimicrobiia	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	rimO	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
SRD3_k127_6444592_0	1313172.YM304_11100	1.255e-171	558.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4CMSA@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Peptidase family M1 domain	-	-	-	ko:K08776	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRD3_k127_6444592_5	436229.JOEH01000004_gene462	1.03e-38	151.0	COG2119@1|root,COG2119@2|Bacteria,2GNR0@201174|Actinobacteria,2NI2G@228398|Streptacidiphilus	201174|Actinobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
SRD3_k127_6444592_4	1229780.BN381_150114	3.022e-76	263.0	COG4122@1|root,COG4122@2|Bacteria,2GQ0Z@201174|Actinobacteria,3UXB0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRD3_k127_6444592_2	1313172.YM304_09250	6.05e-115	391.0	COG3387@1|root,COG3387@2|Bacteria,2GKU7@201174|Actinobacteria,4CN1W@84992|Acidimicrobiia	84992|Acidimicrobiia	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6444592_3	397278.JOJN01000009_gene3698	4.48e-86	310.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria,4DPDW@85009|Propionibacteriales	201174|Actinobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRD3_k127_6444592_1	1003195.SCAT_1409	1.413e-145	474.0	COG0438@1|root,COG0438@2|Bacteria,2GMXE@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRD3_k127_6447700_0	222534.KB893745_gene2669	2.905e-91	308.0	COG0438@1|root,COG0438@2|Bacteria,2GK8D@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD3_k127_6447700_1	326424.FRAAL1772	2.374e-50	197.0	COG1572@1|root,COG1572@2|Bacteria,2I56C@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF3367)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3367
SRD3_k127_6447869_3	28042.GU90_09085	5.843e-41	154.0	COG2227@1|root,COG2227@2|Bacteria,2H217@201174|Actinobacteria	201174|Actinobacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6447869_2	1394178.AWOO02000012_gene3751	4.658e-115	376.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4ENQG@85012|Streptosporangiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	hdhA	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	1.1.1.159	ko:K00076	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRD3_k127_6447869_0	58123.JOFJ01000014_gene5170	1.638e-176	578.0	COG3804@1|root,COG3804@2|Bacteria,2GKE3@201174|Actinobacteria,4EHGY@85012|Streptosporangiales	201174|Actinobacteria	S	dihydrodipicolinate reductase	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
SRD3_k127_6447869_1	1160137.KB907308_gene6699	6.097e-116	398.0	2BYTM@1|root,2Z7KC@2|Bacteria,2GJ6K@201174|Actinobacteria,4FU8Z@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6457071_0	391625.PPSIR1_06983	2.884e-170	547.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,2YUK3@29|Myxococcales	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRD3_k127_6457071_4	525904.Tter_1310	5.465e-34	138.0	COG0288@1|root,COG0288@2|Bacteria,2NR8X@2323|unclassified Bacteria	2|Bacteria	H	Reversible hydration of carbon dioxide	cah	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRD3_k127_6457071_5	1906.SFRA_21615	2.765e-27	130.0	COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRD3_k127_6457071_3	1254432.SCE1572_04805	1.63e-41	161.0	COG3615@1|root,COG3615@2|Bacteria,1QVHF@1224|Proteobacteria,43CNV@68525|delta/epsilon subdivisions,2X7W5@28221|Deltaproteobacteria,2Z2KG@29|Myxococcales	28221|Deltaproteobacteria	P	protein domain, possibly involved in tellurite resistance	-	-	-	-	-	-	-	-	-	-	-	-	DUF1971,DUF3565
SRD3_k127_6457071_1	287986.DV20_05870	1.234e-71	256.0	COG0500@1|root,COG2226@2|Bacteria,2I3BB@201174|Actinobacteria,4E2F9@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRD3_k127_6457071_6	999541.bgla_1g20580	6.839e-20	104.0	2EIDG@1|root,33C4V@2|Bacteria,1N0P4@1224|Proteobacteria,2VYCP@28216|Betaproteobacteria,1K9BA@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6457071_2	1463853.JOHW01000035_gene6586	5.729e-42	174.0	COG0627@1|root,COG0627@2|Bacteria,2GJX4@201174|Actinobacteria	201174|Actinobacteria	M	Esterase	fbpB	GO:0001968,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009273,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010876,GO:0010954,GO:0016020,GO:0016043,GO:0016740,GO:0016746,GO:0016747,GO:0019222,GO:0019899,GO:0022607,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0033036,GO:0035375,GO:0040007,GO:0042221,GO:0042546,GO:0043207,GO:0044044,GO:0044085,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0045862,GO:0046467,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071554,GO:0071702,GO:0071704,GO:0071766,GO:0071769,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:1901135,GO:1901137,GO:1901576,GO:1903317,GO:1903319,GO:1903509	2.3.1.122,2.3.1.20	ko:K18851	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Esterase
SRD3_k127_6476315_2	1121877.JQKF01000002_gene1631	4.237e-18	90.0	2DDS5@1|root,2ZJ1Y@2|Bacteria,2HDMP@201174|Actinobacteria,4CP3T@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6476315_3	525909.Afer_0921	2.767e-12	74.0	2AN5U@1|root,31D3R@2|Bacteria,2HGRH@201174|Actinobacteria,4CNU6@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6476315_1	1229780.BN381_400023	2.075e-18	96.0	COG0454@1|root,COG0456@2|Bacteria,2HBQK@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRD3_k127_6476315_0	1229780.BN381_400022	4.482e-26	113.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	MA20_42070	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRD3_k127_647728_5	1313172.YM304_10880	1.288e-33	134.0	COG5496@1|root,COG5496@2|Bacteria,2IKZP@201174|Actinobacteria	201174|Actinobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRD3_k127_647728_6	935839.JAGJ01000009_gene594	2.457e-06	59.0	COG0738@1|root,COG0738@2|Bacteria,2GRCY@201174|Actinobacteria,4F5A6@85017|Promicromonosporaceae	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_647728_0	525909.Afer_0479	5.881e-225	721.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4CMS4@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRD3_k127_647728_1	1123320.KB889747_gene7192	3.207e-192	614.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria	201174|Actinobacteria	IQ	synthetase	fadD19	GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009605,GO:0009607,GO:0009987,GO:0015645,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0030312,GO:0032787,GO:0042546,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051087,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0075136,GO:1901576	6.2.1.42	ko:K00666,ko:K18688	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_647728_4	561175.KB894094_gene1776	3.255e-54	205.0	COG1335@1|root,COG1335@2|Bacteria,2I81Y@201174|Actinobacteria,4EINJ@85012|Streptosporangiales	201174|Actinobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRD3_k127_647728_3	909613.UO65_4816	9.145e-98	339.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria,4E13R@85010|Pseudonocardiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRD3_k127_647728_2	298654.FraEuI1c_1928	7.198e-161	514.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_6479897_0	357808.RoseRS_4265	6.141e-40	164.0	COG1216@1|root,COG1216@2|Bacteria,2G7UG@200795|Chloroflexi,3764Q@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
SRD3_k127_6479897_1	1206101.AZXC01000015_gene4957	1.227e-28	127.0	COG1216@1|root,COG1216@2|Bacteria,2GKTW@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
SRD3_k127_6481470_3	443255.SCLAV_4704	8.056e-08	55.0	COG0372@1|root,COG0372@2|Bacteria,2GM3G@201174|Actinobacteria	201174|Actinobacteria	C	Citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
SRD3_k127_6481470_0	1157637.KB892105_gene1843	1.806e-137	457.0	COG0372@1|root,COG0372@2|Bacteria,2GKST@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the citrate synthase family	citA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRD3_k127_6481470_1	1206720.BAFQ01000206_gene5195	1.359e-62	218.0	COG2230@1|root,COG2230@2|Bacteria,2IHZD@201174|Actinobacteria	201174|Actinobacteria	M	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRD3_k127_6481470_2	525909.Afer_1069	1.674e-41	163.0	2EFBW@1|root,3394U@2|Bacteria,2H758@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6483659_2	1463821.JOGR01000004_gene2378	5.75e-37	143.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4EZPA@85014|Glycomycetales	201174|Actinobacteria	S	Haemolysin-III related	hlyIII	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRD3_k127_6483659_3	587753.EY04_12600	3.615e-33	139.0	2C82G@1|root,32RK9@2|Bacteria,1MZV5@1224|Proteobacteria,1SAWR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRD3_k127_6483659_1	1041522.MCOL_V205610	2.429e-41	160.0	COG1309@1|root,COG1309@2|Bacteria,2GNR9@201174|Actinobacteria,237HD@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD3_k127_6483659_0	436229.JOEH01000051_gene6274	1.026e-195	637.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria	201174|Actinobacteria	T	PFAM MMPL domain protein	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRD3_k127_6497683_0	525909.Afer_0543	2.826e-179	563.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CMQU@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRD3_k127_6497683_2	1229780.BN381_210073	1.501e-30	124.0	2FF8Q@1|root,3476J@2|Bacteria,2H7PN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6497683_1	1089545.KB913037_gene369	8.19e-70	241.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria,4E086@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase carnithine racemase	echA21	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD3_k127_6509167_2	1121877.JQKF01000001_gene1304	3.679e-05	52.0	2AN61@1|root,31D3Y@2|Bacteria,2HGRS@201174|Actinobacteria,4CNUM@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115
SRD3_k127_6509167_0	512565.AMIS_1760	1.354e-229	734.0	COG1770@1|root,COG1770@2|Bacteria,2GNA9@201174|Actinobacteria,4DAD5@85008|Micromonosporales	201174|Actinobacteria	E	Oligopeptidase b	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRD3_k127_6509167_1	525909.Afer_0543	4.522e-158	501.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CMQU@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRD3_k127_6510202_3	1211815.CBYP010000060_gene3045	1.388e-17	87.0	COG2905@1|root,COG2905@2|Bacteria,2GQMA@201174|Actinobacteria,4EX04@85013|Frankiales	201174|Actinobacteria	T	Domain of unknown function (DUF1918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1918
SRD3_k127_6510202_0	1045009.AFXQ01000017_gene264	7.181e-139	450.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,1W8QY@1268|Micrococcaceae	201174|Actinobacteria	S	alcohol dehydrogenase	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_6510202_1	1452536.JARE01000016_gene2174	2.257e-27	123.0	COG0248@1|root,COG0248@2|Bacteria,2GMME@201174|Actinobacteria,4FKY7@85023|Microbacteriaceae	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx1	GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRD3_k127_6510202_5	446470.Snas_4381	1.48e-13	79.0	2E479@1|root,32Z35@2|Bacteria,2GQXY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6510202_2	36809.MAB_0703c	4.52e-25	109.0	2DMG6@1|root,32RB5@2|Bacteria,2GMQI@201174|Actinobacteria,233G6@1762|Mycobacteriaceae	201174|Actinobacteria	S	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRD3_k127_6522198_3	981369.JQMJ01000004_gene6284	2.261e-50	185.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,2NFRT@228398|Streptacidiphilus	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_6522198_0	392499.Swit_3306	5.194e-168	555.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2K2PD@204457|Sphingomonadales	204457|Sphingomonadales	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.41	ko:K18687	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R10769	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_6522198_2	479432.Sros_2090	5.642e-107	359.0	COG1028@1|root,COG1028@2|Bacteria,2GN3D@201174|Actinobacteria,4EFK1@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRD3_k127_6522198_1	1343740.M271_44405	7.057e-161	529.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE30	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_6522198_4	525897.Dbac_1499	2.735e-49	182.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2WIKW@28221|Deltaproteobacteria,2M7UU@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
SRD3_k127_6535416_2	557599.MKAN_25880	3.658e-18	93.0	COG1073@1|root,COG1073@2|Bacteria,2GNST@201174|Actinobacteria,237Q1@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the UPF0255 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRD3_k127_6535416_0	1229780.BN381_130179	1.009e-85	293.0	COG2267@1|root,COG2267@2|Bacteria,2I6HT@201174|Actinobacteria	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRD3_k127_6535416_1	1429046.RR21198_2720	2.169e-45	177.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria,4G18A@85025|Nocardiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
SRD3_k127_6535416_3	1121877.JQKF01000002_gene1631	7.098e-10	67.0	2DDS5@1|root,2ZJ1Y@2|Bacteria,2HDMP@201174|Actinobacteria,4CP3T@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6544324_2	1121877.JQKF01000016_gene162	5.616e-37	147.0	COG2345@1|root,COG2345@2|Bacteria,2HGTI@201174|Actinobacteria,4CNV8@84992|Acidimicrobiia	84992|Acidimicrobiia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRD3_k127_6544324_0	1229780.BN381_310060	3.384e-100	341.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,3UWEF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRD3_k127_6544324_1	1223543.GP2_053_00170	8.63e-59	216.0	COG3000@1|root,COG3000@2|Bacteria,2HR3N@201174|Actinobacteria,4GD7J@85026|Gordoniaceae	201174|Actinobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRD3_k127_6553714_0	106370.Francci3_2878	2.174e-97	323.0	COG0778@1|root,COG0778@2|Bacteria,2I2R7@201174|Actinobacteria,4EVZZ@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM Cob(II)yrinic acid a,c-diamide reductase	bluB	-	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
SRD3_k127_6553714_2	670307.HYPDE_26178	5.179e-70	256.0	COG1940@1|root,COG1940@2|Bacteria,1NSQA@1224|Proteobacteria,2TSPZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GK	Transcriptional regulator sugar kinase	-	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRD3_k127_6553714_1	469383.Cwoe_0785	2.623e-93	325.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,4CRRX@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRD3_k127_658445_5	345341.KUTG_07221	4.568e-42	156.0	COG3576@1|root,COG3576@2|Bacteria,2I3PF@201174|Actinobacteria,4EDZ3@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRD3_k127_658445_3	1370120.AUWR01000016_gene3770	2.376e-121	402.0	COG1735@1|root,COG1735@2|Bacteria,2GMZ6@201174|Actinobacteria,2360H@1762|Mycobacteriaceae	201174|Actinobacteria	S	Phosphotriesterase	php	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
SRD3_k127_658445_2	469383.Cwoe_2757	1.296e-163	542.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4CSBX@84995|Rubrobacteria	84995|Rubrobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRD3_k127_658445_4	358823.DF19_18920	1.745e-64	234.0	COG0500@1|root,COG0500@2|Bacteria,2IS1H@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRD3_k127_658445_1	106370.Francci3_3012	5.65e-210	663.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4ERK8@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM glutamate synthase, NADH NADPH, small subunit	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3858c	Fer4_20,Pyr_redox_2
SRD3_k127_658445_0	365528.KB891219_gene928	0.0	1537.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2GN09@201174|Actinobacteria,4ERS2@85013|Frankiales	201174|Actinobacteria	E	Glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRD3_k127_658825_0	1380354.JIAN01000007_gene381	5.765e-52	201.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRD3_k127_658825_1	287986.DV20_06095	2.25e-41	160.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4E1KK@85010|Pseudonocardiales	201174|Actinobacteria	KT	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD3_k127_658825_2	1223545.GS4_45_00150	1.332e-19	96.0	COG2197@1|root,COG2197@2|Bacteria,2GN3A@201174|Actinobacteria,4GDVE@85026|Gordoniaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	chiR	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD3_k127_6588398_4	768671.ThimaDRAFT_1948	3.41e-18	88.0	COG4424@1|root,COG4424@2|Bacteria,1RGI6@1224|Proteobacteria,1S85X@1236|Gammaproteobacteria,1X13Z@135613|Chromatiales	135613|Chromatiales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRD3_k127_6588398_2	439235.Dalk_0008	3.373e-27	125.0	COG3551@1|root,COG3551@2|Bacteria,1PFY4@1224|Proteobacteria,439ZE@68525|delta/epsilon subdivisions,2X1Z4@28221|Deltaproteobacteria,2MNSP@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6588398_3	1265313.HRUBRA_00612	6.578e-26	124.0	COG0438@1|root,COG1216@1|root,COG3551@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,COG3551@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1J9M2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_2
SRD3_k127_6588398_1	404589.Anae109_0093	1.422e-48	188.0	COG2227@1|root,COG2227@2|Bacteria,1QTWG@1224|Proteobacteria,42XHD@68525|delta/epsilon subdivisions,2WT8V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRD3_k127_6588398_0	404589.Anae109_0092	8.873e-61	230.0	COG1215@1|root,COG1215@2|Bacteria,1RJNP@1224|Proteobacteria,42ST7@68525|delta/epsilon subdivisions,2X7I3@28221|Deltaproteobacteria,2Z24R@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRD3_k127_660403_0	298655.KI912266_gene2620	4.379e-118	402.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
SRD3_k127_660403_2	298655.KI912266_gene2619	4.608e-59	232.0	COG0411@1|root,COG0411@2|Bacteria,2ICYZ@201174|Actinobacteria	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRD3_k127_660403_1	298655.KI912266_gene2618	3.542e-60	219.0	COG0410@1|root,COG0410@2|Bacteria,2I8GT@201174|Actinobacteria,4EVDG@85013|Frankiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRD3_k127_660403_3	263358.VAB18032_05415	3.252e-08	56.0	COG2890@1|root,COG2890@2|Bacteria,2I407@201174|Actinobacteria,4DMH4@85008|Micromonosporales	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRD3_k127_6621786_3	1382304.JNIL01000001_gene2466	3.554e-34	149.0	COG1835@1|root,COG1835@2|Bacteria,1TPTG@1239|Firmicutes,4HB7R@91061|Bacilli,278XK@186823|Alicyclobacillaceae	91061|Bacilli	I	Acyltransferase family	yvhB	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRD3_k127_6621786_0	1449976.KALB_4798	1.164e-78	276.0	COG2172@1|root,COG2172@2|Bacteria,2GKU6@201174|Actinobacteria,4E0A3@85010|Pseudonocardiales	201174|Actinobacteria	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS
SRD3_k127_6621786_5	1095772.CAHH01000065_gene303	8.298e-23	113.0	COG0791@1|root,COG3170@1|root,COG0791@2|Bacteria,COG3170@2|Bacteria,2GIWB@201174|Actinobacteria	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
SRD3_k127_6621786_1	1246995.AFR_04305	3.387e-75	271.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6621786_2	1278073.MYSTI_07841	4.915e-50	184.0	COG5592@1|root,COG5592@2|Bacteria,1RI8J@1224|Proteobacteria,42XM7@68525|delta/epsilon subdivisions,2WSTY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRD3_k127_6621786_4	981369.JQMJ01000004_gene2194	1.594e-30	121.0	COG0809@1|root,COG0809@2|Bacteria,2GN51@201174|Actinobacteria,2NH5A@228398|Streptacidiphilus	201174|Actinobacteria	J	Queuosine biosynthesis protein	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRD3_k127_6623717_1	1288083.AUKR01000020_gene1751	2.779e-43	165.0	COG4221@1|root,COG4221@2|Bacteria,2GQNJ@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRD3_k127_6623717_2	1313172.YM304_13980	6.255e-17	93.0	COG1184@1|root,COG1184@2|Bacteria,2H70W@201174|Actinobacteria	201174|Actinobacteria	J	Initiation factor 2 subunit family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6623717_0	1121877.JQKF01000003_gene1502	1.307e-80	275.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4CN01@84992|Acidimicrobiia	84992|Acidimicrobiia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRD3_k127_6640089_0	1313172.YM304_37900	9.416e-96	325.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4CMYV@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferase 4-like domain	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
SRD3_k127_6640089_1	1229780.BN381_60050	7.852e-39	150.0	COG1396@1|root,COG1396@2|Bacteria,2IKVI@201174|Actinobacteria,3UXII@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRD3_k127_6640089_2	1313172.YM304_37910	8.943e-20	94.0	2DP8R@1|root,32UKH@2|Bacteria	2|Bacteria	-	-	amfC	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6693739_3	33876.JNXY01000039_gene6642	6.978e-22	108.0	COG1477@1|root,COG1477@2|Bacteria,2H74Y@201174|Actinobacteria,4DDH1@85008|Micromonosporales	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRD3_k127_6693739_0	266940.Krad_1135	5.295e-179	581.0	COG0465@1|root,COG0465@2|Bacteria,2I9X7@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the AAA ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
SRD3_k127_6693739_1	351607.Acel_0145	1.753e-93	324.0	COG2146@1|root,COG2259@1|root,COG2146@2|Bacteria,COG2259@2|Bacteria,2IKSY@201174|Actinobacteria,4ETHF@85013|Frankiales	201174|Actinobacteria	P	PFAM Rieske 2Fe-2S	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	Rieske
SRD3_k127_6693739_2	1394178.AWOO02000107_gene5811	7.545e-54	196.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4EGJ6@85012|Streptosporangiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	tcrA	GO:0000156,GO:0000160,GO:0003674,GO:0005575,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0016020,GO:0023051,GO:0023052,GO:0023057,GO:0035556,GO:0044464,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070297,GO:0070298,GO:0071944,GO:1902531,GO:1902532	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD3_k127_6722016_1	345341.KUTG_05236	2.126e-08	63.0	COG1040@1|root,COG1040@2|Bacteria,2IFV8@201174|Actinobacteria,4ECIE@85010|Pseudonocardiales	201174|Actinobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRD3_k127_6722016_0	931627.MycrhDRAFT_2394	9.566e-96	320.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,23ABY@1762|Mycobacteriaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_6723224_6	58123.JOFJ01000003_gene2073	3.28e-85	290.0	COG4221@1|root,COG4221@2|Bacteria,2I8VU@201174|Actinobacteria,4ENKB@85012|Streptosporangiales	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_6723224_11	1283283.ATXA01000001_gene1186	6.354e-32	141.0	COG0683@1|root,COG0683@2|Bacteria,2GRZ9@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRD3_k127_6723224_3	298655.KI912266_gene2620	1.823e-108	376.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
SRD3_k127_6723224_7	298653.Franean1_4040	4.357e-77	267.0	COG0411@1|root,COG0411@2|Bacteria,2ICYZ@201174|Actinobacteria	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRD3_k127_6723224_10	298655.KI912266_gene2618	3.186e-63	233.0	COG0410@1|root,COG0410@2|Bacteria,2I8GT@201174|Actinobacteria,4EVDG@85013|Frankiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRD3_k127_6723224_9	28444.JODQ01000015_gene1650	1.598e-68	244.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4EHQ6@85012|Streptosporangiales	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_6723224_4	767817.Desgi_0469	6.799e-102	373.0	COG0183@1|root,COG0183@2|Bacteria,1TT8U@1239|Firmicutes,24AD9@186801|Clostridia	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	DUF35_N,Thiolase_C,Thiolase_N,ketoacyl-synt
SRD3_k127_6723224_12	309800.C498_00440	8.284e-32	143.0	COG1545@1|root,COG3425@1|root,arCOG01285@2157|Archaea,arCOG01767@2157|Archaea,2XTWE@28890|Euryarchaeota,23TJ1@183963|Halobacteria	183963|Halobacteria	I	COG3425 3-hydroxy-3-methylglutaryl CoA synthase	acaA	-	2.3.3.10	ko:K01641,ko:K07068	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C,DUF35_N,OB_aCoA_assoc
SRD3_k127_6723224_0	298654.FraEuI1c_2890	1.945e-143	470.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4ERYE@85013|Frankiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_6723224_15	1379698.RBG1_1C00001G1376	5.75e-07	62.0	COG5424@1|root,COG5424@2|Bacteria	2|Bacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	CP_1111	GO:0005575,GO:0005576	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2,TENA_THI-4
SRD3_k127_6723224_2	485913.Krac_8294	1.812e-117	418.0	COG0183@1|root,COG0183@2|Bacteria,2G80D@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRD3_k127_6723224_8	1123023.JIAI01000003_gene2845	6.545e-73	266.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4DZ01@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_6723224_1	886293.Sinac_0706	2.467e-125	410.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_25
SRD3_k127_6723224_5	28042.GU90_03945	6.638e-88	310.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZX5@85010|Pseudonocardiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_6723224_13	47839.CCAU010000004_gene1135	3.578e-25	113.0	COG3631@1|root,COG3631@2|Bacteria,2GWQT@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRD3_k127_6723224_14	1120934.KB894403_gene405	2.788e-13	75.0	COG1946@1|root,COG1946@2|Bacteria	2|Bacteria	I	acyl-CoA hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRD3_k127_6743949_1	1968.JOEV01000010_gene1662	1.764e-10	72.0	COG4934@1|root,COG4934@2|Bacteria,2H5BC@201174|Actinobacteria	201174|Actinobacteria	O	Pro-kumamolisin, activation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pro-kuma_activ
SRD3_k127_6743949_0	1313172.YM304_26410	3.225e-148	482.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4CMYY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
SRD3_k127_6743949_2	365528.KB891159_gene5354	0.0001242	44.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4ERRC@85013|Frankiales	201174|Actinobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRD3_k127_6745967_0	1122247.C731_2414	1.387e-64	230.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,2347J@1762|Mycobacteriaceae	201174|Actinobacteria	J	Hemolysin TlyA	tlyA	GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRD3_k127_6745967_1	1313172.YM304_24880	1.561e-64	233.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4CN3D@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRD3_k127_6745967_2	1313172.YM304_24890	2.748e-44	171.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4CMY1@84992|Acidimicrobiia	84992|Acidimicrobiia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRD3_k127_67517_1	1313172.YM304_16080	5.615e-97	325.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4CMSF@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,S1
SRD3_k127_67517_4	525909.Afer_0642	3.357e-27	126.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4CNBM@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRD3_k127_67517_2	1313172.YM304_16060	7.938e-79	287.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4CN39@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRD3_k127_67517_3	1229780.BN381_330073	1.196e-74	264.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,3UWK5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
SRD3_k127_67517_5	525909.Afer_0639	9.628e-21	104.0	COG0858@1|root,COG0858@2|Bacteria,2HGGX@201174|Actinobacteria,4CNEB@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRD3_k127_67517_0	525909.Afer_0638	9.359e-238	743.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CMS2@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRD3_k127_6778954_1	381666.H16_B0367	2.174e-89	306.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHB0@28216|Betaproteobacteria,1K17R@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRD3_k127_6778954_0	44454.NF84_20405	2.705e-174	559.0	COG1063@1|root,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria,23300@1762|Mycobacteriaceae	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_6779661_1	1120936.KB907212_gene5075	1.84e-183	583.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4EG41@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme	alkK	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_6779661_2	1206741.BAFX01000095_gene4534	8.935e-103	348.0	COG0387@1|root,COG0387@2|Bacteria,2IA57@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sodium calcium exchanger	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
SRD3_k127_6779661_4	1003195.SCAT_5399	4.897e-30	128.0	COG2364@1|root,COG2364@2|Bacteria,2GKA1@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6779661_3	1452535.JARD01000004_gene3513	1.26e-94	346.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4FMB4@85023|Microbacteriaceae	201174|Actinobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRD3_k127_6779661_0	1123024.AUII01000021_gene79	4.901e-306	950.0	COG1060@1|root,COG1060@2|Bacteria,2GK83@201174|Actinobacteria,4DX6M@85010|Pseudonocardiales	201174|Actinobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRD3_k127_6784514_4	1123023.JIAI01000012_gene9123	7.008e-26	110.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4E0JW@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC transporter	nodI	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
SRD3_k127_6784514_3	351607.Acel_0745	3.912e-75	263.0	COG0842@1|root,COG0842@2|Bacteria,2GVC2@201174|Actinobacteria,4ESWF@85013|Frankiales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRD3_k127_6784514_1	40571.JOEA01000016_gene124	7.547e-82	297.0	COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria,4E020@85010|Pseudonocardiales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRD3_k127_6784514_0	1089544.KB912942_gene1761	0.0	1075.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4E1HP@85010|Pseudonocardiales	201174|Actinobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,HAD,Hydrolase,Hydrolase_3
SRD3_k127_6784514_2	1089544.KB912942_gene1606	3.648e-80	283.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2GM3U@201174|Actinobacteria,4E8B0@85010|Pseudonocardiales	201174|Actinobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
SRD3_k127_6784971_0	351607.Acel_0516	1.129e-92	323.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4EXC4@85013|Frankiales	201174|Actinobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	devS	GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HisKA_3
SRD3_k127_6784971_1	525909.Afer_0692	4.211e-21	96.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,4CNTJ@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRD3_k127_6796995_1	1313172.YM304_18720	1.071e-180	580.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4CMPN@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRD3_k127_6796995_2	1313172.YM304_18700	7.205e-106	356.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4CMY6@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54
SRD3_k127_6796995_0	1313172.YM304_18690	1.11e-266	862.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4CMQE@84992|Acidimicrobiia	84992|Acidimicrobiia	D	RecF/RecN/SMC N terminal domain	-	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N
SRD3_k127_6796995_3	1313172.YM304_18680	1.25e-59	223.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,4CN5C@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	mutM	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRD3_k127_6796995_4	67275.JOAP01000028_gene204	8.204e-36	141.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria	201174|Actinobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRD3_k127_6801935_4	298655.KI912267_gene6882	8.084e-54	196.0	COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria	201174|Actinobacteria	S	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRD3_k127_6801935_3	269800.Tfu_1889	2.697e-57	210.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria,4EFXG@85012|Streptosporangiales	201174|Actinobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRD3_k127_6801935_0	557599.MKAN_07990	6.146e-224	705.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria,23361@1762|Mycobacteriaceae	201174|Actinobacteria	P	flavoprotein involved in K transport	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	FMO-like,K_oxygenase,Pyr_redox_3
SRD3_k127_6801935_1	1211815.CBYP010000067_gene115	2.738e-193	611.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4ETRJ@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE1_1	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_6801935_5	1048339.KB913029_gene3483	8.716e-21	100.0	COG0776@1|root,COG0776@2|Bacteria,2GV0M@201174|Actinobacteria,4ET0M@85013|Frankiales	201174|Actinobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006355,GO:0006725,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010106,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019725,GO:0030003,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0040007,GO:0042262,GO:0042592,GO:0042594,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046916,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0060255,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090143,GO:0090304,GO:0097100,GO:0097159,GO:0098771,GO:0140110,GO:1901360,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRD3_k127_6801935_2	1288494.EBAPG3_9460	6.515e-191	617.0	COG3593@1|root,COG3593@2|Bacteria,1P6A1@1224|Proteobacteria,2VXIJ@28216|Betaproteobacteria,372Z6@32003|Nitrosomonadales	28216|Betaproteobacteria	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
SRD3_k127_6805293_2	1229780.BN381_360018	8.006e-46	187.0	COG1020@1|root,COG1020@2|Bacteria,2I5H8@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the long-chain O-acyltransferase family	-	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRD3_k127_6805293_0	1229780.BN381_360021	5.36e-144	472.0	COG1073@1|root,COG1073@2|Bacteria,2I8SP@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6805293_1	298655.KI912266_gene4972	5.061e-131	443.0	28JDP@1|root,2Z97Z@2|Bacteria,2I9EC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6805293_3	257310.BB2849	2.104e-29	127.0	COG2120@1|root,COG2120@2|Bacteria,1RI1F@1224|Proteobacteria,2VSXD@28216|Betaproteobacteria,3T43D@506|Alcaligenaceae	28216|Betaproteobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRD3_k127_6821886_3	398767.Glov_1770	3.118e-19	89.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2WWMK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
SRD3_k127_6821886_0	1229780.BN381_10343	1.987e-225	759.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,3UWC4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	RecG wedge domain	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon
SRD3_k127_6821886_2	1227261.HMPREF0043_00711	2.236e-26	112.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4D6AF@85005|Actinomycetales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRD3_k127_6821886_1	28444.JODQ01000007_gene5844	2.29e-78	273.0	COG1042@1|root,COG1670@1|root,COG1042@2|Bacteria,COG1670@2|Bacteria,2GKN1@201174|Actinobacteria,4EH0E@85012|Streptosporangiales	201174|Actinobacteria	CJ	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRD3_k127_6823374_3	272631.ML1209	5.303e-31	131.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,233IP@1762|Mycobacteriaceae	201174|Actinobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0016020,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1559	PALP,Thr_dehydrat_C
SRD3_k127_6823374_0	40571.JOEA01000009_gene3333	3.32e-102	347.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4E4JX@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_6823374_4	1206733.BAGC01000033_gene4086	1.164e-22	107.0	COG4319@1|root,COG4319@2|Bacteria,2IBWU@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRD3_k127_6823374_2	263358.VAB18032_29931	1.349e-85	292.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4D9TH@85008|Micromonosporales	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD3_k127_6823374_1	469383.Cwoe_4507	6.622e-99	352.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria,4CQ9D@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRD3_k127_6823481_2	682795.AciX8_3775	7.77e-18	98.0	COG1520@1|root,COG1520@2|Bacteria,3Y2H2@57723|Acidobacteria,2JM3H@204432|Acidobacteriia	204432|Acidobacteriia	S	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	PQQ_3
SRD3_k127_6823481_3	1235457.C404_19075	1.432e-09	72.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria,1K4GD@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Amino acid amide ABC transporter substrate-binding protein, HAAT family	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRD3_k127_6823481_0	1283283.ATXA01000014_gene3570	4.711e-79	286.0	COG0411@1|root,COG0559@1|root,COG4177@1|root,COG0411@2|Bacteria,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EU1E@85013|Frankiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRD3_k127_6823481_1	1075090.GOAMR_51_00470	1.445e-68	244.0	COG3845@1|root,COG3845@2|Bacteria,2I5SB@201174|Actinobacteria,4GE28@85026|Gordoniaceae	201174|Actinobacteria	S	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
SRD3_k127_6874769_2	1229780.BN381_290093	9.464e-38	155.0	COG0457@1|root,COG0457@2|Bacteria	1229780.BN381_290093|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6874769_1	292459.STH2403	9.857e-86	295.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes	1239|Firmicutes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRD3_k127_6874769_0	284031.JNXD01000003_gene3754	8.597e-140	452.0	COG1830@1|root,COG1830@2|Bacteria,2I9V1@201174|Actinobacteria	201174|Actinobacteria	G	PFAM deoxyribose-phosphate aldolase phospho-2- dehydro-3-deoxyheptonate aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SRD3_k127_6886759_6	1380356.JNIK01000014_gene3480	8.766e-17	82.0	COG1235@1|root,COG1235@2|Bacteria,2IJCH@201174|Actinobacteria	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRD3_k127_6886759_3	298655.KI912266_gene991	1.003e-78	273.0	COG2197@1|root,COG2197@2|Bacteria,2IIDD@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD3_k127_6886759_5	1206741.BAFX01000065_gene5366	2.992e-30	129.0	COG2197@1|root,COG2197@2|Bacteria,2INZX@201174|Actinobacteria	201174|Actinobacteria	T	Pfam Response regulator receiver	-	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRD3_k127_6886759_1	28444.JODQ01000001_gene2425	4.352e-132	453.0	COG4585@1|root,COG4585@2|Bacteria,2GMMU@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRD3_k127_6886759_2	1380356.JNIK01000014_gene3474	9.611e-84	298.0	COG1136@1|root,COG1136@2|Bacteria,2IDE8@201174|Actinobacteria,4EX5W@85013|Frankiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD3_k127_6886759_0	1380356.JNIK01000014_gene3473	1.237e-152	503.0	COG2114@1|root,COG2197@1|root,COG2114@2|Bacteria,COG2197@2|Bacteria,2GJRI@201174|Actinobacteria,4EU4G@85013|Frankiales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
SRD3_k127_6886759_4	448385.sce3770	6.967e-37	143.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42Y0Z@68525|delta/epsilon subdivisions,2WT7J@28221|Deltaproteobacteria,2YWBV@29|Myxococcales	28221|Deltaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRD3_k127_6889330_1	1380386.JIAW01000001_gene4698	5.771e-33	135.0	2A6ZN@1|root,30VUS@2|Bacteria,2H1PU@201174|Actinobacteria,23D4W@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRD3_k127_6889330_0	390989.JOEG01000001_gene5175	4.845e-41	171.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4D8UX@85008|Micromonosporales	201174|Actinobacteria	T	Signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,EAL,GGDEF,PAS,PAS_4,PAS_9
SRD3_k127_6889330_2	1313172.YM304_02000	1.257e-29	121.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria,4CN2E@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Reductase C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C
SRD3_k127_6920693_2	366602.Caul_4421	3.962e-28	117.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2TTMG@28211|Alphaproteobacteria,2KF7T@204458|Caulobacterales	204458|Caulobacterales	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRD3_k127_6920693_0	1229780.BN381_110026	2.136e-47	181.0	2F3QB@1|root,33WH4@2|Bacteria,2H50W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_6920693_3	1206725.BAFU01000007_gene4207	2.598e-18	98.0	COG1539@1|root,COG1539@2|Bacteria,2IHSW@201174|Actinobacteria,4G2EK@85025|Nocardiaceae	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0008150,GO:0040007	1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8	ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840	R03503,R03504,R11037,R11073	RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRD3_k127_6920693_1	1313172.YM304_16820	7.447e-40	153.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,2H3G6@201174|Actinobacteria,4CN7Q@84992|Acidimicrobiia	84992|Acidimicrobiia	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	-	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SRD3_k127_6920693_4	1229780.BN381_110029	0.000729	44.0	COG5495@1|root,COG5495@2|Bacteria,2HGVN@201174|Actinobacteria,3UXIN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520
SRD3_k127_6923354_6	1397278.AYMV01000007_gene286	4.431e-23	99.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4FK7Q@85023|Microbacteriaceae	201174|Actinobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRD3_k127_6923354_1	525909.Afer_1269	1.936e-115	386.0	COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,4CP58@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRD3_k127_6923354_4	1120936.KB907220_gene1929	1.528e-31	130.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4EIYX@85012|Streptosporangiales	201174|Actinobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRD3_k127_6923354_0	1229780.BN381_330095	4.245e-128	421.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,3UWEM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	PhoH-like protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRD3_k127_6923354_3	2002.JOEQ01000001_gene4709	1.123e-40	155.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4EJSG@85012|Streptosporangiales	201174|Actinobacteria	FG	HIT domain	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
SRD3_k127_6923354_7	1121877.JQKF01000022_gene2279	2.748e-17	88.0	2A7D0@1|root,30WA0@2|Bacteria,2HH43@201174|Actinobacteria,4CP42@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRD3_k127_6923354_2	1121877.JQKF01000022_gene2296	2.306e-48	180.0	COG1396@1|root,COG1396@2|Bacteria,2I569@201174|Actinobacteria,4CN5U@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRD3_k127_6923354_5	1229780.BN381_80273	2.628e-25	110.0	COG1385@1|root,COG1385@2|Bacteria,2GTKX@201174|Actinobacteria,3UWZU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRD3_k127_6947532_0	215803.DB30_6391	2.046e-72	259.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,42TE9@68525|delta/epsilon subdivisions,2WPGF@28221|Deltaproteobacteria,2YUH5@29|Myxococcales	28221|Deltaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_6947532_2	290397.Adeh_0418	1.214e-38	166.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1QYFP@1224|Proteobacteria,43CBV@68525|delta/epsilon subdivisions,2X7MN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA
SRD3_k127_6947532_3	518766.Rmar_1797	6.369e-15	82.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1FJ5I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Bacterial regulatory protein, Fis family	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRD3_k127_6947532_1	106370.Francci3_2659	4.03e-65	229.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4ET1B@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_6952668_1	1313172.YM304_18430	2.334e-35	153.0	COG5011@1|root,COG5011@2|Bacteria,2GIS7@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
SRD3_k127_6952668_0	1229780.BN381_80100	1.887e-195	616.0	COG1032@1|root,COG1032@2|Bacteria,2GJY1@201174|Actinobacteria,3UX71@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRD3_k127_6954339_2	525909.Afer_0369	2.518e-83	289.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria,4CMPH@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
SRD3_k127_6954339_0	1121877.JQKF01000009_gene578	7.837e-210	670.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4CMQ2@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S
SRD3_k127_6954339_3	1121877.JQKF01000009_gene579	2.656e-62	239.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4CN1U@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRD3_k127_6954339_1	1121877.JQKF01000009_gene580	1.574e-206	661.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4CMP9@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRD3_k127_6954339_4	1313172.YM304_04080	1.215e-53	196.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4CN4G@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRD3_k127_6954339_5	1121877.JQKF01000009_gene582	1.052e-11	66.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4CMXA@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRD3_k127_6959016_4	525368.HMPREF0591_5137	1.897e-41	172.0	COG1960@1|root,COG1960@2|Bacteria,2GITF@201174|Actinobacteria,236CQ@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRD3_k127_6959016_2	882083.SacmaDRAFT_2063	4.573e-103	349.0	COG1545@1|root,COG1545@2|Bacteria,2GM2A@201174|Actinobacteria,4DXM7@85010|Pseudonocardiales	201174|Actinobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,MaoC_dehydrat_N,OB_aCoA_assoc
SRD3_k127_6959016_0	1240349.ANGC01000004_gene1816	4.4e-152	492.0	COG1960@1|root,COG1960@2|Bacteria,2GIXS@201174|Actinobacteria,4FUI9@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_6959016_1	2002.JOEQ01000012_gene5808	1.032e-122	406.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4EFPE@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	1.14.13.141	ko:K15981	ko00984,ko01120,map00984,map01120	-	R09859,R11357	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRD3_k127_6959016_3	1298864.AUEQ01000002_gene6087	2.342e-87	303.0	COG2141@1|root,COG2141@2|Bacteria,2GJT1@201174|Actinobacteria,2330F@1762|Mycobacteriaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_6959016_5	1121106.JQKB01000027_gene1866	9.933e-41	166.0	COG2141@1|root,COG2141@2|Bacteria,1R76K@1224|Proteobacteria,2VF18@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_6966961_0	351607.Acel_0114	1.785e-160	518.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4ERX6@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRD3_k127_6966961_1	1894.JOER01000081_gene6248	2.276e-36	142.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRD3_k127_6997202_0	1229780.BN381_80401	8.502e-98	323.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,3UW79@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRD3_k127_6997202_2	1206731.BAGB01000068_gene7014	1.23e-92	309.0	COG0778@1|root,COG0778@2|Bacteria,2GKG5@201174|Actinobacteria,4G04D@85025|Nocardiaceae	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRD3_k127_6997202_8	479433.Caci_5451	6.639e-07	59.0	COG0577@1|root,COG0577@2|Bacteria,2GMH5@201174|Actinobacteria	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRD3_k127_6997202_6	285535.JOEY01000007_gene8350	6.932e-51	203.0	COG0577@1|root,COG0577@2|Bacteria,2GMH5@201174|Actinobacteria	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRD3_k127_6997202_4	1416759.AYMR01000013_gene2440	1.647e-65	248.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4FMNI@85023|Microbacteriaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX
SRD3_k127_6997202_7	247156.NFA_43620	6.918e-42	171.0	COG1668@1|root,COG1668@2|Bacteria,2I9MY@201174|Actinobacteria,4FWJ8@85025|Nocardiaceae	201174|Actinobacteria	CP	ABC-2 family transporter protein	yhaP	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRD3_k127_6997202_3	1449353.JQMQ01000005_gene805	1.037e-91	312.0	COG4152@1|root,COG4152@2|Bacteria,2I2DK@201174|Actinobacteria,2NF6B@228398|Streptacidiphilus	201174|Actinobacteria	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRD3_k127_6997202_1	525909.Afer_0300	2.988e-97	331.0	COG0842@1|root,COG0842@2|Bacteria,2GJGH@201174|Actinobacteria,4CNME@84992|Acidimicrobiia	84992|Acidimicrobiia	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRD3_k127_6997202_5	1121877.JQKF01000052_gene437	7.956e-55	195.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CP50@84992|Acidimicrobiia	84992|Acidimicrobiia	V	Domain of unknown function (DUF4162)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRD3_k127_7053456_3	1380347.JNII01000005_gene3515	5.178e-63	218.0	28HGI@1|root,2Z9T0@2|Bacteria,2ICRF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_7053456_5	1114959.SZMC14600_10328	1.523e-49	177.0	COG5207@1|root,COG5207@2|Bacteria,2IKW9@201174|Actinobacteria,4E5S8@85010|Pseudonocardiales	201174|Actinobacteria	O	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
SRD3_k127_7053456_0	1229780.BN381_10243	7.387e-164	539.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRD3_k127_7053456_1	1048339.KB913029_gene4038	1.503e-118	412.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EUV2@85013|Frankiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRD3_k127_7053456_6	1229780.BN381_10244	5.611e-07	63.0	2FACV@1|root,342M7@2|Bacteria,2H6AW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_7053456_4	479435.Kfla_5998	8.761e-60	214.0	COG0030@1|root,COG0030@2|Bacteria,2IMS8@201174|Actinobacteria,4DWR1@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family	-	-	2.1.1.184	ko:K00561	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	RrnaAD
SRD3_k127_7053456_2	342113.DM82_3533	4.332e-101	342.0	COG3511@1|root,COG3511@2|Bacteria,1R78F@1224|Proteobacteria,2VXFB@28216|Betaproteobacteria,1KHWW@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
SRD3_k127_7080594_0	882083.SacmaDRAFT_2990	3.146e-158	526.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4DXVG@85010|Pseudonocardiales	201174|Actinobacteria	G	hydrolase, family 65, central catalytic	kojP	-	2.4.1.230	ko:K10231	-	-	-	-	ko00000,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SRD3_k127_7080594_3	1172179.AUKV01000023_gene2076	5.835e-14	79.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria	201174|Actinobacteria	K	pyridoxamine 5-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	HTH_3,HTH_31,Pyridox_ox_2
SRD3_k127_7080594_1	1150864.MILUP08_40532	5.03e-73	254.0	COG0637@1|root,COG0637@2|Bacteria,2I2IT@201174|Actinobacteria,4D9YP@85008|Micromonosporales	201174|Actinobacteria	S	Beta-phosphoglucomutase family hydrolase	-	GO:0003674,GO:0003824,GO:0008801,GO:0016853,GO:0016866,GO:0016868	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
SRD3_k127_7080594_2	1035308.AQYY01000001_gene3293	5.365e-42	160.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspX	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564	-	ko:K06335,ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRD3_k127_7085394_2	1205910.B005_1956	3.634e-07	59.0	COG2267@1|root,COG2267@2|Bacteria,2GM56@201174|Actinobacteria,4EGU1@85012|Streptosporangiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
SRD3_k127_7085394_0	469383.Cwoe_4507	1.331e-84	307.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria,4CQ9D@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRD3_k127_7085394_1	1449976.KALB_8332	1.79e-81	278.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4E1TR@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD3_k127_7097273_0	223184.AS25_03555	7.225e-68	260.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,1W8CU@1268|Micrococcaceae	201174|Actinobacteria	S	Glycosyl transferase family 2	ppm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRD3_k127_7097273_1	477641.MODMU_1884	6.177e-57	216.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4ET2I@85013|Frankiales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRD3_k127_7097273_2	656024.FsymDg_0692	2.106e-50	190.0	COG0392@1|root,COG0392@2|Bacteria,2GZ8W@201174|Actinobacteria	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	2.3.2.3	ko:K07027,ko:K14205,ko:K20468	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
SRD3_k127_7111873_1	1121877.JQKF01000012_gene331	6.778e-64	227.0	28KBH@1|root,2Z9YH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_7111873_0	1121877.JQKF01000012_gene330	6.249e-87	295.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRD3_k127_7111873_5	1122138.AQUZ01000098_gene7764	2.056e-29	124.0	COG4243@1|root,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4,VKOR
SRD3_k127_7111873_3	105420.BBPO01000056_gene3451	5.143e-53	197.0	2D9QC@1|root,32TTR@2|Bacteria,2IK1S@201174|Actinobacteria,2NG5Q@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_7111873_2	105425.BBPL01000059_gene5044	1.021e-56	215.0	arCOG03842@1|root,30WW9@2|Bacteria,2IDJ1@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF929
SRD3_k127_7111873_4	1313172.YM304_42670	1.826e-33	135.0	2CQNK@1|root,332VM@2|Bacteria,2HGHQ@201174|Actinobacteria,4CNEW@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Family of unknown function (DUF5318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5318
SRD3_k127_7137909_0	457429.ABJI02000831_gene2495	1.268e-190	616.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRD3_k127_7137909_2	1121877.JQKF01000008_gene667	4.026e-93	323.0	COG2222@1|root,COG2222@2|Bacteria,2IN5A@201174|Actinobacteria,4CNJ1@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
SRD3_k127_7137909_4	1229780.BN381_10201	7.167e-20	105.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SRD3_k127_7137909_1	1121877.JQKF01000008_gene665	4.386e-162	522.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4CMU2@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRD3_k127_7137909_3	1229780.BN381_10199	1.426e-22	98.0	COG5617@1|root,COG5617@2|Bacteria,2H32H@201174|Actinobacteria	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_7154060_2	525909.Afer_1128	1.689e-14	74.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4CN3Y@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRD3_k127_7154060_3	446462.Amir_0554	7.014e-08	63.0	COG3895@1|root,COG3895@2|Bacteria	2|Bacteria	O	Periplasmic Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4232,LprI,MliC
SRD3_k127_7154060_1	700508.D174_04075	3.413e-104	348.0	COG0604@1|root,COG0604@2|Bacteria,2GKYZ@201174|Actinobacteria,233HW@1762|Mycobacteriaceae	201174|Actinobacteria	C	Quinone oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_7154060_0	479434.Sthe_1357	7.093e-113	385.0	COG1506@1|root,COG1506@2|Bacteria,2G5NN@200795|Chloroflexi,27YSI@189775|Thermomicrobia	189775|Thermomicrobia	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRD3_k127_7180844_3	1254432.SCE1572_06970	6.274e-05	54.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,439XR@68525|delta/epsilon subdivisions,2WVH6@28221|Deltaproteobacteria,2Z0UX@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRD3_k127_7180844_1	644966.Tmar_0551	6.039e-20	99.0	COG4175@1|root,COG4175@2|Bacteria,1UHNE@1239|Firmicutes,24F1A@186801|Clostridia	186801|Clostridia	E	pfam abc	-	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran
SRD3_k127_7180844_0	469383.Cwoe_3291	3.711e-159	525.0	COG0477@1|root,COG1846@1|root,COG0477@2|Bacteria,COG1846@2|Bacteria,2GJ09@201174|Actinobacteria,4CP7Q@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_7180844_2	1056816.JAFQ01000004_gene294	2.678e-17	87.0	COG1846@1|root,COG1846@2|Bacteria,2HGXY@201174|Actinobacteria,4G27B@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRD3_k127_7184041_0	405948.SACE_2968	3.131e-72	257.0	COG0304@1|root,COG0304@2|Bacteria,2IAET@201174|Actinobacteria,4E090@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRD3_k127_7184594_8	298655.KI912266_gene6090	5.461e-19	97.0	2A2HJ@1|root,30QV0@2|Bacteria,2IN3M@201174|Actinobacteria,4EVZY@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_7184594_3	1298863.AUEP01000002_gene1487	1.469e-65	241.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4DRHK@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRD3_k127_7184594_2	1385520.N802_18155	8.269e-72	251.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4FEH7@85021|Intrasporangiaceae	201174|Actinobacteria	T	LuxR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRD3_k127_7184594_5	1246448.ANAZ01000002_gene3799	9.45e-53	192.0	COG1309@1|root,COG1309@2|Bacteria,2IMHK@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD3_k127_7184594_6	1122138.AQUZ01000012_gene5940	5.81e-49	188.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD3_k127_7184594_0	1108045.GORHZ_040_00180	1.245e-97	327.0	COG0426@1|root,COG0426@2|Bacteria,2GJT6@201174|Actinobacteria	201174|Actinobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
SRD3_k127_7184594_9	365528.KB891210_gene2149	1.281e-06	59.0	COG2050@1|root,COG2050@2|Bacteria,2H2K4@201174|Actinobacteria	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRD3_k127_7184594_4	1394178.AWOO02000024_gene5605	4.417e-63	232.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_7184594_1	1313172.YM304_33260	2.658e-95	329.0	COG1226@1|root,COG3273@1|root,COG1226@2|Bacteria,COG3273@2|Bacteria,2HGEC@201174|Actinobacteria,4CNCJ@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRD3_k127_7184594_7	1123024.AUII01000025_gene2162	2.103e-35	139.0	COG1393@1|root,COG1393@2|Bacteria,2IHRP@201174|Actinobacteria,4E4AG@85010|Pseudonocardiales	201174|Actinobacteria	P	Belongs to the ArsC family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
SRD3_k127_7188817_1	953739.SVEN_5702	8.115e-07	63.0	COG2120@1|root,COG2120@2|Bacteria,2GRQY@201174|Actinobacteria	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRD3_k127_7188817_0	357808.RoseRS_3616	2.861e-102	353.0	COG3525@1|root,COG3525@2|Bacteria,2G609@200795|Chloroflexi,376QW@32061|Chloroflexia	32061|Chloroflexia	G	Glycoside hydrolase, family 20	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
SRD3_k127_7197516_6	1121877.JQKF01000004_gene1124	3.818e-16	87.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CMS2@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRD3_k127_7197516_7	1120954.ATXE01000001_gene2532	2.805e-10	68.0	COG2740@1|root,COG2740@2|Bacteria	2|Bacteria	K	Nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K02600,ko:K07742	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	DUF448
SRD3_k127_7197516_2	1121877.JQKF01000004_gene1125	1.639e-149	492.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4CMPR@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRD3_k127_7197516_5	1313172.YM304_15870	4.442e-23	110.0	COG0779@1|root,COG0779@2|Bacteria,2HH26@201174|Actinobacteria,4CP28@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRD3_k127_7197516_4	1120950.KB892757_gene6499	1.134e-34	138.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria,4DS34@85009|Propionibacteriales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
SRD3_k127_7197516_0	1449355.JQNR01000005_gene4633	8.665e-201	635.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRD3_k127_7197516_1	525909.Afer_0633	4.206e-182	583.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4CMRA@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRD3_k127_7197516_3	525909.Afer_0632	4.52e-69	246.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4CMZX@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRD3_k127_7199114_1	1463903.JOIZ01000004_gene4765	7.794e-26	115.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria	201174|Actinobacteria	S	DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRD3_k127_7199114_2	40571.JOEA01000011_gene2297	1.107e-12	80.0	COG1073@1|root,COG1073@2|Bacteria,2GNUS@201174|Actinobacteria,4E3BH@85010|Pseudonocardiales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRD3_k127_7199114_0	1120936.KB907221_gene2141	6.182e-28	124.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_7224347_2	1123320.KB889585_gene1751	8.622e-08	60.0	COG0596@1|root,COG0596@2|Bacteria,2GJYS@201174|Actinobacteria	201174|Actinobacteria	NU	Alpha beta hydrolase	slpD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRD3_k127_7224347_1	1223523.H340_01554	2.43e-97	332.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the FPG family	mutM1	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRD3_k127_7224347_0	1122247.C731_0728	3.837e-140	454.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,232FY@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	fadD19_2	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_7243032_2	35754.JNYJ01000008_gene3324	1.363e-19	94.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4D9KI@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRD3_k127_7243032_1	1122939.ATUD01000002_gene1172	3.033e-43	169.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CPVX@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRD3_k127_7243032_0	525909.Afer_1128	1.003e-47	176.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4CN3Y@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRD3_k127_7243032_3	1029824.AFID01000003_gene295	0.0001728	51.0	2E5RJ@1|root,330G5@2|Bacteria,2GQFX@201174|Actinobacteria,1WA4E@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF4232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4232
SRD3_k127_7243491_2	469371.Tbis_1502	3.743e-34	136.0	COG1846@1|root,COG1846@2|Bacteria,2GP6A@201174|Actinobacteria,4E4Z2@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRD3_k127_7243491_0	1122611.KB903941_gene2261	5.795e-80	275.0	28HG7@1|root,2Z7S3@2|Bacteria,2GMJK@201174|Actinobacteria,4EIT6@85012|Streptosporangiales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N,Wyosine_form
SRD3_k127_7243491_1	525909.Afer_1558	2.286e-66	239.0	COG0682@1|root,COG0682@2|Bacteria,2HGGR@201174|Actinobacteria,4CNDX@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
SRD3_k127_7259072_0	404589.Anae109_0527	2.595e-112	377.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2WJDE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DNA recombination protein RmuC	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRD3_k127_7267963_0	1120948.KB903240_gene3914	1.984e-89	299.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4DZM2@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRD3_k127_7267963_2	1035308.AQYY01000001_gene1662	3.857e-30	124.0	COG1733@1|root,COG1733@2|Bacteria	2|Bacteria	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRD3_k127_7267963_1	1122622.ATWJ01000002_gene794	3.909e-38	149.0	COG0265@1|root,COG0265@2|Bacteria,2INQH@201174|Actinobacteria	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRD3_k127_7273906_1	1313172.YM304_19290	6.433e-106	359.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4CNR5@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRD3_k127_7273906_8	525909.Afer_0682	6.233e-27	117.0	2ERJT@1|root,33J59@2|Bacteria,2HGGQ@201174|Actinobacteria,4CNDW@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF3040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3040
SRD3_k127_7273906_4	1313172.YM304_36430	8.465e-84	295.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRD3_k127_7273906_5	1121877.JQKF01000004_gene1085	2.916e-49	181.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,4CN5M@84992|Acidimicrobiia	84992|Acidimicrobiia	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRD3_k127_7273906_6	935866.JAER01000024_gene3108	2.516e-38	159.0	COG0095@1|root,COG0095@2|Bacteria,2GTPJ@201174|Actinobacteria	201174|Actinobacteria	H	Lipoate-protein ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_7273906_10	278957.ABEA03000006_gene4189	1.369e-12	80.0	COG4272@1|root,COG4272@2|Bacteria,46YG6@74201|Verrucomicrobia,3K9I0@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1634
SRD3_k127_7273906_3	1144275.COCOR_02615	2.02e-86	293.0	COG0730@1|root,COG0730@2|Bacteria,1NJ47@1224|Proteobacteria,42QRS@68525|delta/epsilon subdivisions,2WN5M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRD3_k127_7273906_9	935866.JAER01000036_gene3436	6.867e-24	106.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4DQJP@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRD3_k127_7273906_2	1313172.YM304_19390	4.061e-95	332.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CN25@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRD3_k127_7273906_0	525909.Afer_1250	2.275e-118	414.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4CN0Q@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRD3_k127_7273906_7	1123405.AUMM01000002_gene393	2.526e-30	126.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,26NI2@186821|Sporolactobacillaceae	91061|Bacilli	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRD3_k127_7295541_7	710111.FraQA3DRAFT_4841	4.389e-14	80.0	28IJ8@1|root,2Z8K6@2|Bacteria,2GIV3@201174|Actinobacteria,4ET84@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	EccE
SRD3_k127_7295541_8	1048339.KB913029_gene464	4.277e-08	65.0	2CRY9@1|root,32SPX@2|Bacteria,2I3EU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TrbL
SRD3_k127_7295541_5	525909.Afer_0202	5.831e-36	139.0	2E3QT@1|root,31FNG@2|Bacteria,2HGTF@201174|Actinobacteria,4CNV3@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_7295541_2	525909.Afer_0201	7.04e-82	292.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CMZJ@84992|Acidimicrobiia	84992|Acidimicrobiia	F	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SRD3_k127_7295541_3	1313172.YM304_07750	1.75e-79	297.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CMYH@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD3_k127_7295541_6	1229780.BN381_10095	8.402e-27	126.0	COG0735@1|root,COG0735@2|Bacteria,2IFHB@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRD3_k127_7295541_0	525909.Afer_0190	2.05e-143	483.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4CMQR@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Seryl-tRNA synthetase N-terminal domain	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRD3_k127_7295541_1	1122939.ATUD01000007_gene2086	6.483e-84	309.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4CRHJ@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRD3_k127_7295541_4	106370.Francci3_1654	7.228e-61	230.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4ESTT@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRD3_k127_73286_4	1278078.G419_14689	7.824e-49	178.0	COG1545@1|root,COG1545@2|Bacteria,2IFQP@201174|Actinobacteria,4G0JI@85025|Nocardiaceae	201174|Actinobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRD3_k127_73286_0	58123.JOFJ01000004_gene1778	5.007e-195	616.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4EH8Z@85012|Streptosporangiales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N,ketoacyl-synt
SRD3_k127_73286_3	1313172.YM304_11240	2.69e-73	271.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0N@201174|Actinobacteria,4CNYM@84992|Acidimicrobiia	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17,4.2.1.18	ko:K01692,ko:K13766	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00036,M00087	R02085,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD3_k127_73286_1	706587.Desti_3650	2.37e-104	359.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria,2MQ47@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
SRD3_k127_73286_2	1229780.BN381_350072	1.214e-89	321.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,3UXC7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Aminotransferase class I and II	bioF	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.3.1.47,6.2.1.14	ko:K00652,ko:K01906	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03209,R03210,R10124	RC00004,RC00014,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iNJ661.Rv1569	Aminotran_1_2
SRD3_k127_7338795_7	638301.HMPREF0444_0036	1.548e-12	77.0	COG0745@1|root,COG0745@2|Bacteria,1UW25@1239|Firmicutes,4I3AW@91061|Bacilli,27HFF@186828|Carnobacteriaceae	91061|Bacilli	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K18987	ko02020,map02020	M00719	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRD3_k127_7338795_8	1120947.ATUX01000006_gene511	8.071e-06	55.0	2ASDQ@1|root,31HT6@2|Bacteria,2HMBW@201174|Actinobacteria,4D6R3@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_7338795_2	1229780.BN381_250088	8.27e-118	404.0	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the long-chain O-acyltransferase family	-	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRD3_k127_7338795_5	656024.FsymDg_1808	7.582e-53	189.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4ESXH@85013|Frankiales	201174|Actinobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRD3_k127_7338795_3	1313172.YM304_38580	2.705e-67	247.0	COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,4CN0M@84992|Acidimicrobiia	84992|Acidimicrobiia	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
SRD3_k127_7338795_1	1157635.KB892035_gene6282	8.642e-138	460.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRD3_k127_7338795_0	402881.Plav_0558	3.08e-214	688.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRD3_k127_7338795_4	1380386.JIAW01000012_gene1800	3.107e-53	202.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,23582@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD3_k127_7340568_1	1206725.BAFU01000091_gene4718	2.51e-156	513.0	COG2070@1|root,COG2070@2|Bacteria,2GKGT@201174|Actinobacteria,4FW5B@85025|Nocardiaceae	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRD3_k127_7340568_6	1229780.BN381_150016	3.522e-25	113.0	COG1309@1|root,COG1309@2|Bacteria,2HGC3@201174|Actinobacteria,3UXK5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD3_k127_7340568_2	479433.Caci_5229	7.15e-118	384.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRD3_k127_7340568_3	479433.Caci_5227	7.753e-114	389.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD3_k127_7340568_4	1123072.AUDH01000005_gene1739	7.42e-72	260.0	COG4122@1|root,COG4122@2|Bacteria,1R9D7@1224|Proteobacteria,2U823@28211|Alphaproteobacteria,2JRYX@204441|Rhodospirillales	204441|Rhodospirillales	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRD3_k127_7340568_8	2074.JNYD01000033_gene6334	3.038e-05	57.0	COG2211@1|root,COG2211@2|Bacteria,2GJZG@201174|Actinobacteria,4EF8Y@85010|Pseudonocardiales	201174|Actinobacteria	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2
SRD3_k127_7340568_5	1382303.JPOM01000001_gene400	5.643e-53	198.0	COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,2U1B8@28211|Alphaproteobacteria,2KH1D@204458|Caulobacterales	204458|Caulobacterales	I	Steryl acetyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRD3_k127_7340568_0	1232410.KI421421_gene3873	4.041e-164	526.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,43SUW@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD3_k127_7340568_7	1041139.KB902713_gene4285	2.925e-20	91.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,4B7AV@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	GO:0003674,GO:0003824,GO:0004029,GO:0004030,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009698,GO:0009699,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019438,GO:0019748,GO:0044237,GO:0044249,GO:0044550,GO:0050269,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901576	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRD3_k127_7379553_0	1463921.JODF01000003_gene2441	2.456e-69	243.0	COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRD3_k127_7379553_1	931627.MycrhDRAFT_4787	6.979e-17	89.0	2CAD5@1|root,32Z7A@2|Bacteria,2IAVC@201174|Actinobacteria,238JW@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_7402975_1	1313172.YM304_22260	7.019e-222	704.0	COG0560@1|root,COG3320@1|root,COG0560@2|Bacteria,COG3320@2|Bacteria,2GJVX@201174|Actinobacteria,4CMQQ@84992|Acidimicrobiia	84992|Acidimicrobiia	EQ	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,NAD_binding_4
SRD3_k127_7402975_2	266117.Rxyl_2111	1.352e-105	365.0	COG1063@1|root,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_7402975_0	525909.Afer_1430	3.426e-251	795.0	COG3875@1|root,COG3875@2|Bacteria,2IAM4@201174|Actinobacteria,4CMV3@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRD3_k127_7402975_3	525909.Afer_1429	8.41e-18	98.0	COG0204@1|root,COG0204@2|Bacteria,2IAXZ@201174|Actinobacteria,4CN1J@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRD3_k127_7421569_5	543632.JOJL01000020_gene686	4.896e-43	168.0	2CMWR@1|root,32SFR@2|Bacteria,2IHG8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_7421569_3	1169161.KB897739_gene2178	1.143e-81	276.0	COG0500@1|root,COG2226@2|Bacteria,2GP9N@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	Methyltransf_25
SRD3_k127_7421569_7	313589.JNB_09129	8.811e-33	139.0	COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria,4FEK4@85021|Intrasporangiaceae	201174|Actinobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRD3_k127_7421569_4	1449068.JMLQ01000002_gene3073	3.802e-63	232.0	COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria,4G0FQ@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
SRD3_k127_7421569_8	103733.JNYO01000049_gene8373	2.735e-19	94.0	2E3KN@1|root,32YIY@2|Bacteria,2GQXH@201174|Actinobacteria,4E6WI@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2630)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2630
SRD3_k127_7421569_6	640132.Srot_2791	3.105e-39	152.0	2DJ5J@1|root,32UCF@2|Bacteria,2II98@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_7421569_2	1120950.KB892740_gene2582	2.628e-93	321.0	COG0154@1|root,COG0154@2|Bacteria,2GSBS@201174|Actinobacteria,4DU83@85009|Propionibacteriales	201174|Actinobacteria	J	Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433,ko:K21801	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRD3_k127_7421569_1	1265310.CCBD010000070_gene35	4.495e-141	456.0	COG4221@1|root,COG4221@2|Bacteria,2I2YS@201174|Actinobacteria,2367K@1762|Mycobacteriaceae	201174|Actinobacteria	S	Short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_7421569_9	525904.Tter_2084	3.107e-13	81.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	CBS
SRD3_k127_7421569_0	590998.Celf_0800	8.015e-198	627.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria,4F21C@85016|Cellulomonadaceae	201174|Actinobacteria	L	ATP dependent DNA ligase C terminal region	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRD3_k127_748722_0	1121877.JQKF01000021_gene2185	2.188e-204	657.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4CMWE@84992|Acidimicrobiia	84992|Acidimicrobiia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRD3_k127_748722_1	1123319.AUBE01000016_gene5928	1.508e-50	186.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
SRD3_k127_80156_0	235985.BBPN01000014_gene5539	2.759e-156	501.0	COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,2NEZW@228398|Streptacidiphilus	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.8.1.20	ko:K22347	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN
SRD3_k127_802076_2	35754.JNYJ01000008_gene3159	7.658e-78	272.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria,4D9QG@85008|Micromonosporales	201174|Actinobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRD3_k127_802076_1	44060.JODL01000028_gene5149	8.857e-126	419.0	COG1797@1|root,COG1797@2|Bacteria,2GJ3R@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source	cobB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2,CbiA,GATase_3
SRD3_k127_802076_0	247634.GPB2148_3615	7.087e-134	456.0	COG5285@1|root,COG5285@2|Bacteria,1NXM8@1224|Proteobacteria	1224|Proteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRD3_k127_802076_3	547163.BN979_04884	8.482e-54	195.0	COG3832@1|root,COG3832@2|Bacteria,2IFZV@201174|Actinobacteria,238M8@1762|Mycobacteriaceae	201174|Actinobacteria	S	polyketide cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRD3_k127_802076_4	189425.PGRAT_21215	0.0005135	50.0	COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,26RF5@186822|Paenibacillaceae	91061|Bacilli	M	Collagen binding domain	M1-568	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind,Gram_pos_anchor,SdrD_B
SRD3_k127_802743_5	69279.BG36_00030	0.0003699	53.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,2TU60@28211|Alphaproteobacteria,43IFY@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	F	glutamine amidotransferase	guaA2	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
SRD3_k127_802743_0	2002.JOEQ01000075_gene4072	1.818e-193	618.0	COG0318@1|root,COG0318@2|Bacteria,2GKZ6@201174|Actinobacteria,4EMIB@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRD3_k127_802743_1	1048339.KB913029_gene661	5.809e-156	509.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ETYU@85013|Frankiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRD3_k127_802743_3	1121877.JQKF01000036_gene1791	1.855e-27	124.0	COG2385@1|root,COG2385@2|Bacteria,2HGNA@201174|Actinobacteria,4CNPA@84992|Acidimicrobiia	84992|Acidimicrobiia	D	sporulation resulting in formation of a cellular spore	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_802743_4	477641.MODMU_4337	1.376e-18	98.0	COG5662@1|root,COG5662@2|Bacteria,2INVC@201174|Actinobacteria	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRD3_k127_802743_2	101510.RHA1_ro00601	3.655e-50	184.0	COG1595@1|root,COG1595@2|Bacteria,2IMV5@201174|Actinobacteria,4G0WH@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRD3_k127_804597_4	479433.Caci_5895	1.403e-78	267.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRD3_k127_804597_3	43354.JOIJ01000011_gene2760	3.974e-97	327.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4DZDR@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD3_k127_804597_8	1095767.CAHD01000239_gene1882	2.404e-28	132.0	28JAE@1|root,2Z957@2|Bacteria,2IFSW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRD3_k127_804597_6	1122611.KB904007_gene7796	4.464e-52	201.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4EIYA@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRD3_k127_804597_7	253839.SSNG_00781	8.687e-47	183.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria	201174|Actinobacteria	I	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRD3_k127_804597_5	110319.CF8_2187	5.987e-61	214.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria,4DMZC@85009|Propionibacteriales	201174|Actinobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRD3_k127_804597_2	1156844.KB891803_gene2344	9.654e-133	446.0	COG0183@1|root,COG0183@2|Bacteria,2GNCM@201174|Actinobacteria	201174|Actinobacteria	I	lipid-transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
SRD3_k127_804597_0	471852.Tcur_3981	2.276e-192	616.0	COG0183@1|root,COG0183@2|Bacteria,2GJ0W@201174|Actinobacteria,4EHB7@85012|Streptosporangiales	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
SRD3_k127_804597_9	1229780.BN381_250095	4.994e-18	91.0	COG1141@1|root,COG1141@2|Bacteria,2GT1Y@201174|Actinobacteria	201174|Actinobacteria	C	Divergent 4Fe-4S mono-cluster	fdxD_2	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
SRD3_k127_804597_1	106370.Francci3_3219	2.182e-145	475.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4ERZ8@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRD3_k127_816721_6	247634.GPB2148_2868	1.082e-25	117.0	COG4221@1|root,COG4221@2|Bacteria,1PH8K@1224|Proteobacteria,1RPDR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRD3_k127_816721_3	47839.CCAU010000011_gene5205	6.497e-88	308.0	2AQ2E@1|root,30RA0@2|Bacteria,2GP9U@201174|Actinobacteria,2389N@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_816721_2	653045.Strvi_1002	4.677e-102	356.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRD3_k127_816721_4	1123320.KB889585_gene1873	4.98e-80	282.0	COG1960@1|root,COG1960@2|Bacteria,2GK9C@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE27	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRD3_k127_816721_1	1123320.KB889585_gene1872	2.643e-178	565.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_816721_0	1463900.JOIX01000030_gene4805	9.401e-190	600.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRD3_k127_816721_5	305700.B447_09608	9.749e-57	206.0	COG1960@1|root,COG1960@2|Bacteria,1P4V3@1224|Proteobacteria,2VNIA@28216|Betaproteobacteria	28216|Betaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRD3_k127_817340_2	1121877.JQKF01000003_gene1511	2.044e-24	109.0	2CD9C@1|root,2ZWAS@2|Bacteria,2GYGD@201174|Actinobacteria,4CNXP@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_817340_1	882083.SacmaDRAFT_3965	9.844e-29	122.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria,4E6RZ@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRD3_k127_817340_0	351607.Acel_1545	1.168e-216	707.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4ERWA@85013|Frankiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpE	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
SRD3_k127_817340_3	1211815.CBYP010000063_gene1880	4.51e-18	94.0	2EK1R@1|root,33DS7@2|Bacteria,2GWKM@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
SRD3_k127_817340_4	309801.trd_A0257	3.798e-05	54.0	COG5401@1|root,COG5401@2|Bacteria,2GA61@200795|Chloroflexi,27Y9M@189775|Thermomicrobia	189775|Thermomicrobia	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRD3_k127_819381_0	1380356.JNIK01000014_gene3476	2.827e-55	220.0	COG0577@1|root,COG0577@2|Bacteria,2GWZR@201174|Actinobacteria,4EVD8@85013|Frankiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRD3_k127_819381_2	1206731.BAGB01000143_gene4255	1.559e-18	88.0	28WG3@1|root,2ZIG8@2|Bacteria,2HCCM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_819381_1	42256.RradSPS_0328	1.464e-48	186.0	COG2202@1|root,COG2203@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2GKEF@201174|Actinobacteria,4CU1G@84995|Rubrobacteria	84995|Rubrobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,PAS_9,SpoIIE
SRD3_k127_896704_0	1123024.AUII01000007_gene4815	3.301e-95	318.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria,4E3XB@85010|Pseudonocardiales	201174|Actinobacteria	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRD3_k127_896704_6	869213.JCM21142_93479	9.228e-05	53.0	COG3194@1|root,COG3194@2|Bacteria	2|Bacteria	F	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source	allA	GO:0003674,GO:0003824,GO:0016829,GO:0016840,GO:0016842,GO:0050385	4.3.2.3	ko:K01483	ko00230,ko01100,map00230,map01100	-	R00776	RC00153,RC00379	ko00000,ko00001,ko01000	-	-	iAF1260.b0505,iBWG_1329.BWG_0382,iECDH10B_1368.ECDH10B_0461,iECDH1ME8569_1439.ECDH1ME8569_0489,iEcDH1_1363.EcDH1_3107,iJO1366.b0505,iJR904.b0505,iY75_1357.Y75_RS02595	Ureidogly_lyase
SRD3_k127_896704_4	469383.Cwoe_5005	1.419e-31	131.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K03490	-	-	-	-	ko00000,ko03000	-	-	-	Cupin_2
SRD3_k127_896704_2	266117.Rxyl_0619	2.686e-85	295.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,4CPZ9@84995|Rubrobacteria	84995|Rubrobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRD3_k127_896704_3	522306.CAP2UW1_2989	2.392e-52	192.0	COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,2VICR@28216|Betaproteobacteria,1KQY8@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Aldolase/RraA	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
SRD3_k127_896704_1	1206744.BAGL01000035_gene366	1.5e-94	320.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria,4FYQ6@85025|Nocardiaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRD3_k127_896704_5	1121937.AUHJ01000010_gene1752	4.199e-16	79.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,464Z9@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRD3_k127_909857_0	1313172.YM304_20570	8.12e-57	208.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4CN6M@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Formyl transferase, C-terminal domain	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRD3_k127_909857_1	1229780.BN381_50154	5.745e-56	212.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,3UWS7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRD3_k127_909857_2	1229780.BN381_50152	5.85e-46	174.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,3UWAF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRD3_k127_925906_10	469383.Cwoe_3159	1.054e-43	179.0	COG2050@1|root,COG2050@2|Bacteria,2HMKZ@201174|Actinobacteria,4CSHW@84995|Rubrobacteria	84995|Rubrobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRD3_k127_925906_7	1206744.BAGL01000125_gene6442	4.422e-74	274.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,4FY7I@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRD3_k127_925906_1	1123320.KB889747_gene7184	1.542e-191	606.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRD3_k127_925906_2	1123320.KB889747_gene7183	6.644e-172	551.0	COG1545@1|root,COG3425@1|root,COG1545@2|Bacteria,COG3425@2|Bacteria,2GP7R@201174|Actinobacteria	201174|Actinobacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C,DUF35_N,OB_aCoA_assoc
SRD3_k127_925906_0	1123320.KB889585_gene1895	6.154e-206	646.0	COG1960@1|root,COG1960@2|Bacteria,2ICK3@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_925906_5	479433.Caci_5357	1.063e-123	426.0	COG1804@1|root,COG1804@2|Bacteria,2IEU2@201174|Actinobacteria	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRD3_k127_925906_8	479433.Caci_5358	1.84e-66	252.0	COG2030@1|root,COG2030@2|Bacteria,2ICZR@201174|Actinobacteria	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRD3_k127_925906_6	479433.Caci_5359	9.002e-75	253.0	COG2030@1|root,COG2030@2|Bacteria,2IPFP@201174|Actinobacteria	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRD3_k127_925906_4	1123320.KB889585_gene1891	3.121e-140	458.0	COG1960@1|root,COG1960@2|Bacteria,2I8MN@201174|Actinobacteria	201174|Actinobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRD3_k127_925906_11	1246445.ANAY01000001_gene365	1.279e-37	153.0	COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria,4EJ0C@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
SRD3_k127_925906_12	1394178.AWOO02000050_gene6225	1.355e-15	80.0	2EA32@1|root,33485@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_925906_3	1380390.JIAT01000009_gene2065	2.528e-140	466.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CRC3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRD3_k127_925906_9	211114.JOEF01000023_gene5707	1.189e-57	214.0	COG4427@1|root,COG4427@2|Bacteria,2HVQW@201174|Actinobacteria,4DX9D@85010|Pseudonocardiales	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
SRD3_k127_927933_3	2045.KR76_13990	1.998e-07	56.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4DQ7H@85009|Propionibacteriales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRD3_k127_927933_2	106370.Francci3_1654	8.665e-16	87.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4ESTT@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRD3_k127_927933_0	1003195.SCAT_1089	1.904e-89	305.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	drrA_2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRD3_k127_927933_1	1229780.BN381_450047	4.237e-16	87.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,3UWDU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRD3_k127_953948_0	525909.Afer_0329	2.229e-66	243.0	COG3643@1|root,COG3643@2|Bacteria,2H8ZI@201174|Actinobacteria,4CNR1@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD_N
SRD3_k127_953948_2	1313172.YM304_07660	5.318e-26	109.0	2CC1Y@1|root,32TCV@2|Bacteria,2HGD4@201174|Actinobacteria,4CNAQ@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRD3_k127_953948_3	1313172.YM304_07670	4.278e-25	107.0	2FBA6@1|root,343GA@2|Bacteria,2H78Y@201174|Actinobacteria,4CN8Z@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRD3_k127_953948_1	1313172.YM304_07800	3.617e-50	187.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4CNC4@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pfam:Zinicin_2	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRD3_k127_95402_0	1313172.YM304_19470	5.424e-114	398.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4CMTG@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRD3_k127_95402_2	1229780.BN381_140009	5.572e-70	266.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,3UWKB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRD3_k127_95402_1	477974.Daud_1437	8.197e-79	281.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2619Y@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRD3_k127_95402_3	1255043.TVNIR_2606	2.194e-13	72.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1WWI1@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRD3_k127_955801_9	285514.JNWO01000003_gene6955	3.96e-28	126.0	COG2050@1|root,COG2050@2|Bacteria,2GKY1@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRD3_k127_955801_5	749414.SBI_01088	1.81e-105	353.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA19	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRD3_k127_955801_1	1122247.C731_3862	3.3e-175	559.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,233JC@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the thiolase family	fadA5	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRD3_k127_955801_2	525909.Afer_1526	1.959e-172	551.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CNIG@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRD3_k127_955801_6	1150864.MILUP08_45588	6.619e-87	306.0	COG2267@1|root,COG2267@2|Bacteria,2I2IM@201174|Actinobacteria,4D8NX@85008|Micromonosporales	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRD3_k127_955801_0	525909.Afer_1538	2.886e-197	636.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4CMUV@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRD3_k127_955801_4	1448857.JFAP01000002_gene1342	4.722e-107	355.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2YMGF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRD3_k127_955801_3	1313172.YM304_12990	1.407e-132	433.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4CMRK@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Isocitrate/isopropylmalate dehydrogenase	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRD3_k127_955801_7	525909.Afer_1535	5.438e-53	197.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4CN6V@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRD3_k127_963379_3	1162668.LFE_0389	6.995e-25	107.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,3J14D@40117|Nitrospirae	40117|Nitrospirae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
SRD3_k127_963379_4	1211819.CALK01000004_gene2359	2.746e-15	83.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,3VP3Q@526524|Erysipelotrichia	526524|Erysipelotrichia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRD3_k127_963379_0	469383.Cwoe_0137	2.838e-104	364.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CRHY@84995|Rubrobacteria	84995|Rubrobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4
SRD3_k127_963379_1	105420.BBPO01000032_gene6512	1.714e-35	142.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,2GP5E@201174|Actinobacteria,2NGYZ@228398|Streptacidiphilus	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SLT,SLT_2
SRD3_k127_963379_2	1048834.TC41_3188	2.158e-28	127.0	2DGGT@1|root,2ZVX8@2|Bacteria,1V6AM@1239|Firmicutes,4HVWB@91061|Bacilli	91061|Bacilli	S	Peptidase A4 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A4
SRD3_k127_976829_11	1121877.JQKF01000004_gene1089	1.229e-49	185.0	COG2120@1|root,COG2120@2|Bacteria,2HF8J@201174|Actinobacteria,4CNQ6@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRD3_k127_976829_12	1313172.YM304_26950	3.937e-47	173.0	COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria,4CN4B@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRD3_k127_976829_7	1313172.YM304_26970	2.44e-78	269.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4CN5D@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRD3_k127_976829_10	1463864.JOGO01000009_gene449	1.833e-50	184.0	COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria	201174|Actinobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpE	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
SRD3_k127_976829_13	1448389.BAVQ01000002_gene2867	5.213e-42	166.0	COG1309@1|root,COG1309@2|Bacteria,2IMHK@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRD3_k127_976829_15	446470.Snas_3147	2.706e-29	126.0	COG0346@1|root,COG0346@2|Bacteria,2GQZ9@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRD3_k127_976829_5	471852.Tcur_1172	2.75e-99	336.0	COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,4EI3Z@85012|Streptosporangiales	201174|Actinobacteria	E	Peptidase dimerisation domain	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRD3_k127_976829_4	1120950.KB892784_gene202	8.078e-111	364.0	COG2171@1|root,COG2171@2|Bacteria,2IBDI@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
SRD3_k127_976829_2	1313172.YM304_26990	7.626e-136	444.0	COG0436@1|root,COG0436@2|Bacteria,2H440@201174|Actinobacteria,4CMXW@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRD3_k127_976829_3	1121877.JQKF01000004_gene1100	1.581e-135	463.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4CMWR@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRD3_k127_976829_14	562970.Btus_1414	1.37e-35	157.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli,2789I@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRD3_k127_976829_6	1229780.BN381_80321	2.205e-90	308.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,3UWH8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRD3_k127_976829_1	1229780.BN381_80317	1.443e-174	559.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,3UW97@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRD3_k127_976829_9	1121877.JQKF01000004_gene1113	7.712e-53	196.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4CNCE@84992|Acidimicrobiia	84992|Acidimicrobiia	E	GHMP kinases N terminal domain	-	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRD3_k127_976829_8	521098.Aaci_0345	1.266e-58	222.0	COG1686@1|root,COG1686@2|Bacteria,1VZJP@1239|Firmicutes	1239|Firmicutes	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
SRD3_k127_976829_0	1229780.BN381_80302	8.366e-202	657.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,3UW6P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRD3_k127_989583_0	1313172.YM304_21110	6.299e-89	308.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4CN2R@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
SRD3_k127_989583_1	931276.Cspa_c09200	6.853e-34	134.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,36E5A@31979|Clostridiaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
## 2291 queries scanned
## Total time (seconds): 12.51568603515625
## Rate: 183.05 q/s