## Fri Nov 15 15:16:44 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin24/SX_3_bin.21.fa -m mmseqs --itype genome -o SX_3_bin.21 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/SX_3_bin.21 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SX3_k127_1011965_4	517418.Ctha_2076	5.282e-06	59.0	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,1FF5N@1090|Chlorobi	1090|Chlorobi	U	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_1011965_1	247490.KSU1_C0449	3.811e-92	326.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
SX3_k127_1011965_3	880073.Calab_0041	6.203e-14	85.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
SX3_k127_1011965_0	247490.KSU1_C0449	2.622e-97	342.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
SX3_k127_1011965_2	1123252.ATZF01000010_gene452	1.052e-22	101.0	COG1695@1|root,COG1695@2|Bacteria,1V85H@1239|Firmicutes,4HJMF@91061|Bacilli	91061|Bacilli	K	PadR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SX3_k127_1032970_2	706587.Desti_4022	4.613e-50	184.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2MQGX@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SX3_k127_1032970_1	760568.Desku_0806	1.737e-82	286.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
SX3_k127_1032970_0	945713.IALB_1465	9.705e-127	424.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SX3_k127_1041257_1	1121396.KB892934_gene3759	3.136e-08	59.0	COG2220@1|root,COG2220@2|Bacteria,1QB9E@1224|Proteobacteria,42N7W@68525|delta/epsilon subdivisions,2WMED@28221|Deltaproteobacteria,2MQ1N@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SX3_k127_1041257_0	448385.sce0639	1.158e-14	77.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2YUGG@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SX3_k127_1041786_1	509191.AEDB02000049_gene4417	7.421e-37	145.0	COG1394@1|root,COG1394@2|Bacteria,1TQ1Y@1239|Firmicutes,247TC@186801|Clostridia,3WHIG@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
SX3_k127_1041786_0	857293.CAAU_0426	1.944e-118	385.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,36DRP@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
SX3_k127_1042971_0	706587.Desti_5055	3.371e-98	333.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria	1224|Proteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Dak2,DegV,Radical_SAM
SX3_k127_1047198_0	1122611.KB903943_gene1418	1.106e-33	149.0	COG3188@1|root,COG5297@1|root,COG3188@2|Bacteria,COG5297@2|Bacteria,2GK92@201174|Actinobacteria,4EFJ7@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolases family 6	-	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_2,Glyco_hydro_6
SX3_k127_1047354_2	518766.Rmar_1077	8.15e-11	74.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,1FKEP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	PFAM TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SX3_k127_1047354_0	246197.MXAN_0939	5.732e-18	96.0	COG5316@1|root,COG5316@2|Bacteria,1N0IJ@1224|Proteobacteria,43BYT@68525|delta/epsilon subdivisions,2WMTY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	N-terminal domain of unknown function (DUF4140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
SX3_k127_1047354_1	395494.Galf_2689	7.392e-12	66.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria,44UYU@713636|Nitrosomonadales	28216|Betaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
SX3_k127_1050827_0	880073.Calab_0453	4.871e-94	315.0	COG2812@1|root,COG2812@2|Bacteria,2NNK7@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SX3_k127_1050827_1	1207063.P24_17558	2.164e-05	49.0	COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria,2JW58@204441|Rhodospirillales	204441|Rhodospirillales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
SX3_k127_1053054_4	575540.Isop_1796	4.886e-09	68.0	COG4932@1|root,COG4932@2|Bacteria,2IYDU@203682|Planctomycetes	203682|Planctomycetes	M	Cna B domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
SX3_k127_1053054_3	384765.SIAM614_14450	1.344e-35	141.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2U9M7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	chain release factor	MA20_05665	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SX3_k127_1053054_1	880072.Desac_2419	5.496e-76	266.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,42M82@68525|delta/epsilon subdivisions,2WKGK@28221|Deltaproteobacteria,2MQEH@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
SX3_k127_1053054_0	194439.CT0198	1.258e-97	336.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SX3_k127_1064170_0	485913.Krac_11459	3.874e-17	94.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SX3_k127_108427_1	1118059.CAHC01000008_gene1253	4.046e-137	440.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,3WCSC@538999|Clostridiales incertae sedis	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
SX3_k127_108427_0	469381.Dpep_2115	9.982e-228	719.0	COG1155@1|root,COG1155@2|Bacteria,3TA3Y@508458|Synergistetes	508458|Synergistetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	atpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
SX3_k127_108427_2	888821.HMPREF9394_0219	5.093e-08	59.0	COG1436@1|root,COG1436@2|Bacteria,1VAX7@1239|Firmicutes,4HMU4@91061|Bacilli,1WRTR@1305|Streptococcus sanguinis	91061|Bacilli	C	ATP synthase (F/14-kDa) subunit	ntpG	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
SX3_k127_108427_3	1499689.CCNN01000006_gene484	4.721e-05	48.0	COG1527@1|root,COG1527@2|Bacteria,1U6WZ@1239|Firmicutes,249XD@186801|Clostridia,36DZ2@31979|Clostridiaceae	186801|Clostridia	C	C subunit	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
SX3_k127_1087883_0	1122176.KB903549_gene1227	5.456e-21	101.0	COG1595@1|root,COG1595@2|Bacteria,4NMAK@976|Bacteroidetes,1ISGD@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM RNA polymerase sigma factor 70, region 4 type 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SX3_k127_1112091_0	635013.TherJR_2375	1.823e-44	165.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia,260ZP@186807|Peptococcaceae	186801|Clostridia	S	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
SX3_k127_1112091_1	1047013.AQSP01000128_gene444	3.393e-25	116.0	2CK1R@1|root,32V4M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_111263_1	1120948.KB903219_gene741	1.649e-07	59.0	COG1287@1|root,COG1287@2|Bacteria,2GMZM@201174|Actinobacteria,4E0ZH@85010|Pseudonocardiales	201174|Actinobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_111263_0	1276220.STAIW_v1c08890	3.199e-08	62.0	COG2001@1|root,COG2001@2|Bacteria,3WTV9@544448|Tenericutes	544448|Tenericutes	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SX3_k127_1120812_3	1163398.AJJP01000153_gene2985	2.284e-14	77.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SX3_k127_1120812_1	926569.ANT_03540	4.234e-61	231.0	COG1839@1|root,COG1839@2|Bacteria,2G6BH@200795|Chloroflexi	200795|Chloroflexi	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
SX3_k127_1120812_2	694429.Pyrfu_0032	5.347e-45	188.0	COG0123@1|root,arCOG00324@2157|Archaea,2XQ13@28889|Crenarchaeota	28889|Crenarchaeota	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SX3_k127_1120812_0	880073.Calab_0319	5.796e-119	402.0	COG3604@1|root,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	nifA	-	-	ko:K02584,ko:K11914	ko02020,map02020	-	-	-	ko00000,ko00001,ko02044,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
SX3_k127_1120812_4	1121127.JAFA01000002_gene1710	2.173e-05	48.0	COG4191@1|root,COG4191@2|Bacteria,1R72V@1224|Proteobacteria,2VJVI@28216|Betaproteobacteria,1K26N@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_7TM
SX3_k127_1126010_1	1218352.B597_004820	1.759e-36	144.0	COG1352@1|root,COG5001@1|root,COG1352@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	5TM-5TMR_LYT,CHASE5,CheB_methylest,CheR,CheR_N,EAL,GGDEF,PAS,PAS_4,PAS_9,Response_reg
SX3_k127_1126010_0	981383.AEWH01000039_gene1785	2.279e-58	226.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli	91061|Bacilli	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_3_3
SX3_k127_1126010_2	316067.Geob_3828	2.808e-22	104.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42S69@68525|delta/epsilon subdivisions,2X5TT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SX3_k127_1137233_2	381666.H16_A2000	3.161e-05	49.0	COG0778@1|root,COG0778@2|Bacteria,1RDJ6@1224|Proteobacteria,2VT3D@28216|Betaproteobacteria,1KCI5@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SX3_k127_1137233_0	1449080.JQMV01000003_gene2047	7.259e-36	149.0	COG0500@1|root,COG2226@2|Bacteria,1WIUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SX3_k127_1137233_1	926560.KE387023_gene1787	1.936e-21	100.0	2A8GS@1|root,30XIR@2|Bacteria,1WMGZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_1142422_0	1242864.D187_004023	3.992e-26	124.0	COG1680@1|root,COG1680@2|Bacteria,1R8N7@1224|Proteobacteria,42WBG@68525|delta/epsilon subdivisions,2WS3Q@28221|Deltaproteobacteria,2YY0X@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SX3_k127_1146583_2	1191523.MROS_2238	6.437e-06	49.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	CBM_6,fn3
SX3_k127_1146583_1	1122927.KB895415_gene4431	1.71e-16	93.0	COG1409@1|root,COG3250@1|root,COG3405@1|root,COG1409@2|Bacteria,COG3250@2|Bacteria,COG3405@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,26TEF@186822|Paenibacillaceae	91061|Bacilli	G	Purple acid Phosphatase, N-terminal domain	ppe1	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_5,F5_F8_type_C,Metallophos,PA14,Pur_ac_phosph_N,SLH,fn3
SX3_k127_1146583_0	1254432.SCE1572_03445	3.044e-123	415.0	COG3866@1|root,COG3866@2|Bacteria	2|Bacteria	G	Pectate lyase	-	-	3.2.1.202,4.2.2.2	ko:K01728,ko:K21606	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	CBM5,GH18	-	Beta_helix,Big_5,CBM_2,CBM_5_12_2,CBM_6,ChiC,Glyco_hydro_18,Lipase_GDSL_2,Pec_lyase_C,Pectinesterase
SX3_k127_1147616_2	946362.XP_004987884.1	0.0003521	45.0	COG1618@1|root,2QVJ8@2759|Eukaryota,38FT1@33154|Opisthokonta	33154|Opisthokonta	O	nucleotide phosphatase activity, acting on free nucleotides	NTPCR	-	3.6.1.15	ko:K06928	ko00230,ko00730,ko01100,map00230,map00730,map01100	-	R00086,R00615	RC00002	ko00000,ko00001,ko01000	-	-	-	NTPase_1
SX3_k127_1147616_0	1047013.AQSP01000134_gene1339	1.901e-58	213.0	COG5012@1|root,COG5012@2|Bacteria,2NQTJ@2323|unclassified Bacteria	2|Bacteria	S	B12 binding domain	-	-	-	ko:K14084	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124	RC00035,RC00732,RC02984	ko00000,ko00001,ko00002	-	-	-	B12-binding,B12-binding_2
SX3_k127_1147616_1	574087.Acear_1072	2.056e-18	89.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,3WA7C@53433|Halanaerobiales	186801|Clostridia	H	PFAM Pterin binding enzyme	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SX3_k127_1157830_0	945713.IALB_1500	1.592e-128	433.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	dsbD	-	1.8.1.8	ko:K04084,ko:K06196	-	-	-	-	ko00000,ko01000,ko02000,ko03110	5.A.1.1,5.A.1.2	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
SX3_k127_1157830_1	446470.Snas_5055	1.35e-71	251.0	COG0179@1|root,COG0179@2|Bacteria,2GKED@201174|Actinobacteria,4F0CB@85014|Glycomycetales	201174|Actinobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SX3_k127_1157830_4	449673.BACSTE_01319	2.633e-36	159.0	COG0438@1|root,COG0438@2|Bacteria,4NM38@976|Bacteroidetes,2FNUT@200643|Bacteroidia,4ANIE@815|Bacteroidaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SX3_k127_1157830_6	429009.Adeg_0162	4.944e-07	52.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,42F5Y@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SX3_k127_1157830_5	743836.AYNA01000145_gene563	1.928e-11	71.0	COG0776@1|root,COG0776@2|Bacteria,1N6FS@1224|Proteobacteria,2V9XC@28211|Alphaproteobacteria,3708U@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Bacterial DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
SX3_k127_1157830_3	679935.Alfi_1227	5.707e-47	178.0	COG0731@1|root,COG0731@2|Bacteria,4NJEM@976|Bacteroidetes,2FMWY@200643|Bacteroidia,22UDB@171550|Rikenellaceae	976|Bacteroidetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
SX3_k127_1157830_2	673860.AciM339_1072	3.628e-53	198.0	COG1167@1|root,arCOG00492@2157|Archaea,2XVD6@28890|Euryarchaeota,3F2Z7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	PFAM Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SX3_k127_1174790_1	4098.XP_009606934.1	2.999e-34	149.0	COG4870@1|root,KOG1543@2759|Eukaryota,38765@33090|Viridiplantae,3GN3N@35493|Streptophyta,44MWF@71274|asterids	35493|Streptophyta	O	Belongs to the peptidase C1 family	-	-	-	ko:K13441	ko04626,map04626	-	-	-	ko00000,ko00001,ko01002	-	-	-	Inhibitor_I29,Peptidase_C1
SX3_k127_1174790_0	880073.Calab_0470	1.567e-57	219.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SX3_k127_1175048_1	1033802.SSPSH_001976	7.742e-08	64.0	COG1538@1|root,COG1538@2|Bacteria,1R705@1224|Proteobacteria,1S0X1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SX3_k127_1175048_0	1499967.BAYZ01000151_gene1668	9.328e-101	336.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SX3_k127_1181259_1	395495.Lcho_3075	2.258e-18	90.0	COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,2VRXN@28216|Betaproteobacteria,1KKYM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SX3_k127_1181259_0	477974.Daud_0439	2.402e-64	227.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,24GY3@186801|Clostridia,262MF@186807|Peptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SX3_k127_1184302_0	1304872.JAGC01000003_gene3619	9.959e-85	289.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,2M8SG@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SX3_k127_1184302_1	1144275.COCOR_01591	6.494e-33	143.0	COG0457@1|root,COG2819@1|root,COG0457@2|Bacteria,COG2819@2|Bacteria,1R54Q@1224|Proteobacteria	1224|Proteobacteria	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
SX3_k127_1184302_2	1449080.JQMV01000003_gene1147	4.717e-07	58.0	COG4719@1|root,COG4719@2|Bacteria,1WJJ8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,LTD,SdrD_B
SX3_k127_1186953_0	1231057.AMGD01000018_gene3610	2.778e-72	255.0	COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HCMX@91061|Bacilli,26FWK@186818|Planococcaceae	91061|Bacilli	D	Phage tail tape measure protein, TP901 family	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
SX3_k127_1191744_0	316067.Geob_1222	1.503e-16	93.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SX3_k127_1193027_2	926549.KI421517_gene2973	7.28e-12	66.0	COG1595@1|root,COG1595@2|Bacteria,4NMYQ@976|Bacteroidetes,47PII@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SX3_k127_1193027_1	926549.KI421517_gene2974	3.301e-40	159.0	COG1413@1|root,COG1413@2|Bacteria,4NIBA@976|Bacteroidetes,47M5K@768503|Cytophagia	976|Bacteroidetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,zf-HC2
SX3_k127_1193027_0	1185876.BN8_00879	1.755e-44	173.0	COG3595@1|root,COG3595@2|Bacteria,4NGRU@976|Bacteroidetes,47MSM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SX3_k127_1195328_0	1047013.AQSP01000106_gene1757	1.572e-185	587.0	COG4690@1|root,COG4690@2|Bacteria,2NQBZ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
SX3_k127_1195328_1	1166018.FAES_0722	6.798e-11	75.0	COG0793@1|root,COG0793@2|Bacteria,4NGGJ@976|Bacteroidetes,47PB5@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SX3_k127_1196002_1	686340.Metal_1171	0.0003961	46.0	COG1538@1|root,COG1538@2|Bacteria,1R8XP@1224|Proteobacteria,1SZE3@1236|Gammaproteobacteria,1XEJN@135618|Methylococcales	135618|Methylococcales	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SX3_k127_1196002_0	1121918.ARWE01000001_gene24	2.973e-74	254.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,42MCM@68525|delta/epsilon subdivisions,2WKRE@28221|Deltaproteobacteria,43SD5@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Rnf-Nqr subunit, membrane protein	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
SX3_k127_1217547_2	1267534.KB906759_gene1989	4.137e-26	109.0	COG0006@1|root,COG0006@2|Bacteria,3Y3I4@57723|Acidobacteria,2JIWQ@204432|Acidobacteriia	204432|Acidobacteriia	E	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SX3_k127_1217547_1	748247.AZKH_2009	9.319e-33	131.0	2E3V1@1|root,32YSA@2|Bacteria,1N7HB@1224|Proteobacteria,2VWDQ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_1217547_0	1047013.AQSP01000071_gene1939	5.356e-209	668.0	COG1297@1|root,COG1297@2|Bacteria,2NP0C@2323|unclassified Bacteria	2|Bacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SX3_k127_1227826_0	523791.Kkor_2137	4.71e-11	74.0	COG0534@1|root,COG0534@2|Bacteria,1QTIW@1224|Proteobacteria,1RZ7Q@1236|Gammaproteobacteria,1XHZ6@135619|Oceanospirillales	135619|Oceanospirillales	V	Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
SX3_k127_1227826_1	1499967.BAYZ01000139_gene164	0.0003265	54.0	COG0526@1|root,COG0526@2|Bacteria,2NPYK@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin-like	resA	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
SX3_k127_1228245_1	1386089.N865_05350	1.071e-12	82.0	COG4733@1|root,COG4733@2|Bacteria,2I7XV@201174|Actinobacteria,4FK2V@85021|Intrasporangiaceae	201174|Actinobacteria	M	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
SX3_k127_1228245_0	96561.Dole_0842	2.963e-14	87.0	COG3209@1|root,COG3386@1|root,COG3209@2|Bacteria,COG3386@2|Bacteria,1MVV1@1224|Proteobacteria,43AER@68525|delta/epsilon subdivisions,2X5UG@28221|Deltaproteobacteria,2MN6Q@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,NHL,RHS_repeat
SX3_k127_1237324_0	1206733.BAGC01000041_gene1970	6.466e-10	70.0	COG5316@1|root,COG5316@2|Bacteria,2GN81@201174|Actinobacteria,4FZQT@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
SX3_k127_123981_2	1232683.ADIMK_2846	6.029e-15	83.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,1Q5AK@1224|Proteobacteria,1S19Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,MarR,MarR_2
SX3_k127_123981_0	448385.sce3387	3.553e-112	385.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_123981_1	1121405.dsmv_3380	1.093e-53	192.0	COG4802@1|root,COG4802@2|Bacteria,1RI70@1224|Proteobacteria,42SXJ@68525|delta/epsilon subdivisions,2WP19@28221|Deltaproteobacteria,2MKJ4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B
SX3_k127_123981_3	1304885.AUEY01000011_gene1737	2.481e-10	61.0	COG0695@1|root,COG0695@2|Bacteria,1NAZM@1224|Proteobacteria,42VIA@68525|delta/epsilon subdivisions,2WR8X@28221|Deltaproteobacteria,2MKPI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM Glutaredoxin	-	-	-	ko:K06191	-	-	-	-	ko00000	-	-	-	Glutaredoxin
SX3_k127_1243584_2	96561.Dole_2968	8.204e-09	57.0	COG0695@1|root,COG0695@2|Bacteria,1NAZM@1224|Proteobacteria,42VIA@68525|delta/epsilon subdivisions,2WR8X@28221|Deltaproteobacteria,2MKPI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM Glutaredoxin	-	-	-	ko:K06191	-	-	-	-	ko00000	-	-	-	Glutaredoxin
SX3_k127_1243584_0	1183438.GKIL_2654	8.581e-41	158.0	COG5516@1|root,COG5516@2|Bacteria	2|Bacteria	S	CGNR zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SX3_k127_1243584_1	1499967.BAYZ01000137_gene110	5.462e-40	161.0	COG1600@1|root,COG1600@2|Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Fer4_16
SX3_k127_1245282_0	1123065.ATWL01000020_gene3526	1.239e-81	283.0	COG1131@1|root,COG1131@2|Bacteria,2IBJD@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SX3_k127_1253454_0	314278.NB231_01354	1.265e-48	180.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1WYG2@135613|Chromatiales	135613|Chromatiales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SX3_k127_1253454_1	552811.Dehly_0765	1.315e-14	78.0	COG0792@1|root,COG0792@2|Bacteria,2G7AR@200795|Chloroflexi,34DD4@301297|Dehalococcoidia	301297|Dehalococcoidia	L	nuclease activity	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SX3_k127_1254730_2	518766.Rmar_2723	2.036e-26	121.0	COG2304@1|root,COG2304@2|Bacteria,4NFQQ@976|Bacteroidetes	976|Bacteroidetes	S	TIGRFAM N-terminal double-transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA
SX3_k127_1254730_1	1379698.RBG1_1C00001G0202	3.534e-102	346.0	COG1721@1|root,COG1721@2|Bacteria,2NP6B@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SX3_k127_1254730_0	1379698.RBG1_1C00001G0201	3.133e-126	411.0	COG0714@1|root,COG0714@2|Bacteria,2NNV8@2323|unclassified Bacteria	2|Bacteria	O	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SX3_k127_1258564_1	1379698.RBG1_1C00001G0752	5.365e-42	160.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	cbiX	-	-	-	-	-	-	-	-	-	-	-	CbiX
SX3_k127_1258564_2	293826.Amet_2131	1.028e-23	107.0	COG3153@1|root,COG3153@2|Bacteria,1VVRU@1239|Firmicutes,24M6C@186801|Clostridia,36K1C@31979|Clostridiaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SX3_k127_1258564_0	1173027.Mic7113_1218	3.304e-62	226.0	COG4826@1|root,COG4826@2|Bacteria,1G29E@1117|Cyanobacteria,1H9A9@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
SX3_k127_1259229_0	439235.Dalk_0482	4.205e-06	60.0	COG1018@1|root,COG4447@1|root,COG1018@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	-
SX3_k127_1261056_1	861299.J421_2540	9.697e-45	176.0	COG0601@1|root,COG0601@2|Bacteria,1ZSXJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SX3_k127_1261056_0	861299.J421_2541	6.261e-108	368.0	COG4166@1|root,COG4166@2|Bacteria,1ZSMX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SX3_k127_1265476_0	1379698.RBG1_1C00001G0936	2.991e-73	254.0	COG1335@1|root,COG1335@2|Bacteria,2NRGH@2323|unclassified Bacteria	2|Bacteria	Q	Isochorismatase family	-	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SX3_k127_1268003_0	1185876.BN8_02757	1.247e-99	338.0	COG3386@1|root,COG3386@2|Bacteria,4NFRT@976|Bacteroidetes,47PGT@768503|Cytophagia	976|Bacteroidetes	G	Major royal jelly protein	-	-	-	-	-	-	-	-	-	-	-	-	MRJP
SX3_k127_1276232_2	596151.DesfrDRAFT_0545	3.802e-25	106.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,42V85@68525|delta/epsilon subdivisions,2WR93@28221|Deltaproteobacteria,2MDHT@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM nitrogen-fixing NifU domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
SX3_k127_1276232_3	575540.Isop_0955	0.0002935	50.0	COG2165@1|root,COG2165@2|Bacteria,2IZP1@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
SX3_k127_1276232_0	1297742.A176_01664	4.394e-91	325.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,42NXB@68525|delta/epsilon subdivisions,2WMBF@28221|Deltaproteobacteria,2YW82@29|Myxococcales	28221|Deltaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SX3_k127_1276232_1	1379698.RBG1_1C00001G0370	6.905e-69	248.0	COG0616@1|root,COG0616@2|Bacteria,2NNKU@2323|unclassified Bacteria	2|Bacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SX3_k127_1277709_2	1265505.ATUG01000003_gene212	6.984e-12	68.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2MHWD@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SX3_k127_1277709_0	379066.GAU_2569	1.256e-145	472.0	COG2805@1|root,COG2805@2|Bacteria,1ZSQE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SX3_k127_1277709_1	335543.Sfum_0117	1.033e-18	87.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MQ93@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	TIGRFAM type IV-A pilus assembly ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
SX3_k127_127923_1	521045.Kole_0574	1.939e-59	219.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
SX3_k127_127923_0	521045.Kole_0573	3.969e-74	258.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	asrB	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K02823,ko:K16951	ko00240,ko00920,ko01100,ko01120,map00240,map00920,map01100,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS12555	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SX3_k127_127923_2	1122611.KB903975_gene3211	4.928e-18	98.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4EGXK@85012|Streptosporangiales	201174|Actinobacteria	C	Molybdopterin oxidoreductase	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SX3_k127_1281870_1	479434.Sthe_2091	5.639e-16	85.0	COG3857@1|root,COG3857@2|Bacteria	2|Bacteria	L	exonuclease activity	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
SX3_k127_1281870_0	479434.Sthe_2092	2.696e-57	221.0	COG1074@1|root,COG1074@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	-	-	3.1.11.5,3.1.12.1,3.6.4.12	ko:K01144,ko:K07464,ko:K16898	-	-	-	-	ko00000,ko01000,ko02048,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SX3_k127_1288435_1	497321.C664_15243	4.994e-25	121.0	COG0279@1|root,COG0615@1|root,COG0279@2|Bacteria,COG0615@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria,2KVWJ@206389|Rhodocyclales	206389|Rhodocyclales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,SIS_2
SX3_k127_1288435_0	515635.Dtur_0599	6.513e-46	184.0	COG1596@1|root,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SX3_k127_1288435_2	861299.J421_3522	1.336e-05	48.0	COG0013@1|root,COG0013@2|Bacteria,1ZT18@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SX3_k127_1299766_0	1499967.BAYZ01000083_gene1022	5.845e-72	256.0	COG3049@1|root,COG3049@2|Bacteria	2|Bacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	AAT,CBAH
SX3_k127_1317147_1	518766.Rmar_2818	1.074e-15	80.0	2DBB2@1|root,2Z858@2|Bacteria,4P25P@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_1317147_0	1379698.RBG1_1C00001G1820	1.107e-43	179.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SX3_k127_1320838_0	626939.HMPREF9443_01816	2.388e-10	71.0	COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4H3ZP@909932|Negativicutes	909932|Negativicutes	S	Serine aminopeptidase, S33	est	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
SX3_k127_1320838_1	635013.TherJR_0978	1.593e-07	55.0	COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,24B04@186801|Clostridia,2670T@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM iron-sulfur cluster binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_16,Fer4_7
SX3_k127_1322153_0	700598.Niako_5053	1.869e-46	184.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IU78@117747|Sphingobacteriia	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SX3_k127_1322153_1	1128421.JAGA01000002_gene1599	3.237e-27	129.0	COG1807@1|root,COG1807@2|Bacteria,2NRMD@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SX3_k127_1322153_2	1047013.AQSP01000106_gene1757	1.137e-15	83.0	COG4690@1|root,COG4690@2|Bacteria,2NQBZ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
SX3_k127_1324541_0	1123371.ATXH01000001_gene1200	9.222e-66	242.0	COG3276@1|root,COG3276@2|Bacteria,2GH20@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SX3_k127_1334351_0	1183438.GKIL_1793	4.246e-62	223.0	COG1063@1|root,COG1063@2|Bacteria,1FZZE@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,Shikimate_DH
SX3_k127_1334351_1	1131269.AQVV01000015_gene2044	5.101e-13	76.0	COG1898@1|root,COG1898@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase activity	fnlB	-	1.1.1.367	ko:K19068	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
SX3_k127_1334351_2	335543.Sfum_1863	1.474e-05	53.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2WK5J@28221|Deltaproteobacteria,2MQ5V@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SX3_k127_1342080_0	1121875.KB907552_gene312	7.821e-226	714.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1HYM8@117743|Flavobacteriia	976|Bacteroidetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SX3_k127_1342080_1	927658.AJUM01000034_gene68	8.085e-174	560.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,2FN1K@200643|Bacteroidia,3XJPB@558415|Marinilabiliaceae	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SX3_k127_1343323_0	552396.HMPREF0863_01219	3.18e-08	64.0	COG2244@1|root,COG2244@2|Bacteria,1TP7R@1239|Firmicutes,3VQ8A@526524|Erysipelotrichia	526524|Erysipelotrichia	S	COG COG2244 Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SX3_k127_1350860_0	880073.Calab_0682	4.491e-23	106.0	COG2067@1|root,COG2067@2|Bacteria,2NQKU@2323|unclassified Bacteria	2|Bacteria	I	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
SX3_k127_1350860_1	880073.Calab_0683	3.835e-10	72.0	COG1404@1|root,COG4932@1|root,COG1404@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CarboxypepD_reg,DUF11,LRR_5,Peptidase_S8,SLH
SX3_k127_13669_0	1121920.AUAU01000009_gene1911	1.948e-91	308.0	COG3104@1|root,COG3104@2|Bacteria	2|Bacteria	E	oligopeptide transport	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	MFS_1
SX3_k127_137649_1	644966.Tmar_1065	1.954e-05	53.0	COG2137@1|root,COG2137@2|Bacteria	2|Bacteria	S	regulation of DNA repair	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SX3_k127_137649_0	644966.Tmar_1223	1.229e-101	337.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WCF6@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SX3_k127_1396236_0	880073.Calab_1380	2.289e-68	237.0	COG1190@1|root,COG1190@2|Bacteria,2NNMH@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
SX3_k127_1396236_1	1123368.AUIS01000016_gene2527	2.543e-35	146.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,2NCEA@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Lipoprotein releasing system transmembrane protein LolC	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SX3_k127_1405202_3	1379698.RBG1_1C00001G1507	2.27e-70	250.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
SX3_k127_1405202_4	1232410.KI421414_gene2862	2.903e-45	174.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria,43TN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
SX3_k127_1405202_0	880073.Calab_0633	9.133e-192	610.0	COG2403@1|root,COG2403@2|Bacteria,2NNTB@2323|unclassified Bacteria	2|Bacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	cpgS	-	-	ko:K05716	-	-	R03298	RC00900	ko00000,ko01000	-	-	-	cobW
SX3_k127_1405202_1	861299.J421_3279	6.925e-127	417.0	COG0045@1|root,COG0045@2|Bacteria,1ZSZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SX3_k127_1405202_2	1382356.JQMP01000003_gene1858	2.402e-109	372.0	COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi,27XS4@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SX3_k127_1410322_1	706587.Desti_4611	2.914e-27	115.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MS96@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SX3_k127_1410322_0	1121930.AQXG01000005_gene666	3.99e-96	324.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1IQGT@117747|Sphingobacteriia	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SX3_k127_1410322_2	1042375.AFPL01000046_gene2013	4.006e-10	64.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,1S9AB@1236|Gammaproteobacteria,468EX@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	DUF167	yggU	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SX3_k127_1416047_0	765910.MARPU_15640	2.355e-37	158.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RZRG@1236|Gammaproteobacteria,1WVXI@135613|Chromatiales	135613|Chromatiales	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SX3_k127_1416047_1	1382356.JQMP01000003_gene1340	5.928e-21	98.0	COG0438@1|root,COG0438@2|Bacteria,2G8W3@200795|Chloroflexi,27Y3X@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
SX3_k127_1426707_1	396588.Tgr7_2366	0.0001355	51.0	COG1073@1|root,COG1073@2|Bacteria,1R61B@1224|Proteobacteria	1224|Proteobacteria	T	TIGRFAM Hydrolase, ortholog 1, exosortase system type 1 associated	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
SX3_k127_1426707_0	909663.KI867150_gene2279	5.804e-88	301.0	COG0037@1|root,COG0037@2|Bacteria,1NKHX@1224|Proteobacteria,42Q26@68525|delta/epsilon subdivisions,2WPER@28221|Deltaproteobacteria,2MSF2@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	TIGRFAM N-acetyl sugar amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_1432271_1	398512.JQKC01000009_gene408	1.717e-32	127.0	COG1543@1|root,COG1543@2|Bacteria,1TPFX@1239|Firmicutes,248UF@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
SX3_k127_1432271_0	321327.CYA_1973	6.977e-165	548.0	COG1449@1|root,COG1449@2|Bacteria,1G0BM@1117|Cyanobacteria,1GYNP@1129|Synechococcus	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
SX3_k127_1432840_2	909663.KI867150_gene2598	1.599e-15	77.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,42SF6@68525|delta/epsilon subdivisions,2WPDP@28221|Deltaproteobacteria,2MQJ8@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SX3_k127_1432840_1	671143.DAMO_0552	2.13e-20	92.0	COG0199@1|root,COG0199@2|Bacteria,2NPW7@2323|unclassified Bacteria	2|Bacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SX3_k127_1432840_0	909663.KI867150_gene2597	2.558e-91	302.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,42QS6@68525|delta/epsilon subdivisions,2WMPD@28221|Deltaproteobacteria,2MR25@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SX3_k127_1435958_0	1379698.RBG1_1C00001G0505	3.571e-58	223.0	COG0308@1|root,COG0308@2|Bacteria,2NPPZ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
SX3_k127_1435958_1	1123073.KB899245_gene76	6.726e-56	206.0	COG0823@1|root,COG0823@2|Bacteria,1MZ1T@1224|Proteobacteria,1RMNE@1236|Gammaproteobacteria,1X7UX@135614|Xanthomonadales	135614|Xanthomonadales	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SX3_k127_1444456_0	1379698.RBG1_1C00001G1445	1.047e-57	209.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NQSG@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2
SX3_k127_1444456_1	240016.ABIZ01000001_gene2101	1.611e-28	121.0	COG0253@1|root,COG0253@2|Bacteria,46SKV@74201|Verrucomicrobia,2ITVJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SX3_k127_1458615_0	1035191.HMPREF0185_01273	2.177e-11	76.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria,2KEXW@204458|Caulobacterales	204458|Caulobacterales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SX3_k127_1458615_1	457570.Nther_2043	1.429e-08	67.0	COG1664@1|root,COG1664@2|Bacteria,1VBC3@1239|Firmicutes,24NSR@186801|Clostridia	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_1459954_2	314278.NB231_13926	9.175e-35	145.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RZRG@1236|Gammaproteobacteria,1WVXI@135613|Chromatiales	135613|Chromatiales	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SX3_k127_1459954_0	335543.Sfum_2577	2.202e-157	508.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,2MR42@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SX3_k127_1459954_4	760192.Halhy_1368	1.117e-08	68.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9	-	CHU_C,PKD,SprB
SX3_k127_1459954_1	110319.CF8_1016	1.535e-59	228.0	COG1524@1|root,COG1524@2|Bacteria,2HY6Q@201174|Actinobacteria,4DT1Q@85009|Propionibacteriales	201174|Actinobacteria	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SX3_k127_1459954_3	243277.VC_A0167	2.762e-16	79.0	COG2859@1|root,COG2859@2|Bacteria,1QU0K@1224|Proteobacteria,1RR22@1236|Gammaproteobacteria,1XW39@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
SX3_k127_146339_2	396588.Tgr7_2367	9.714e-27	128.0	COG1073@1|root,COG1073@2|Bacteria,1RDA0@1224|Proteobacteria,1S647@1236|Gammaproteobacteria,1WYMV@135613|Chromatiales	135613|Chromatiales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SX3_k127_146339_1	935863.AWZR01000003_gene2832	1.279e-47	192.0	COG3307@1|root,COG3307@2|Bacteria,1N4HJ@1224|Proteobacteria,1SWM6@1236|Gammaproteobacteria,1X57W@135614|Xanthomonadales	135614|Xanthomonadales	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SX3_k127_146339_0	1163408.UU9_04157	3.324e-104	350.0	2DBFX@1|root,2Z917@2|Bacteria,1P4PR@1224|Proteobacteria,1RWCW@1236|Gammaproteobacteria,1X36T@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_1474017_0	927658.AJUM01000043_gene814	2.146e-05	55.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,2FN2J@200643|Bacteroidia,3XJDF@558415|Marinilabiliaceae	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SX3_k127_1481086_0	926549.KI421517_gene821	1.543e-63	229.0	COG0384@1|root,COG0384@2|Bacteria,4NMWV@976|Bacteroidetes,47PEQ@768503|Cytophagia	976|Bacteroidetes	S	phenazine biosynthesis protein PhzF family	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
SX3_k127_1489264_0	344747.PM8797T_26205	1.162e-67	246.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	DUF1863,PQQ,PQQ_2,PQQ_3
SX3_k127_1495888_0	330214.NIDE4119	1.052e-100	350.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,3J0J1@40117|Nitrospirae	40117|Nitrospirae	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	-	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SX3_k127_1495888_1	593750.Metfor_1460	1.412e-13	73.0	COG0637@1|root,arCOG02293@2157|Archaea,2Y7WB@28890|Euryarchaeota	28890|Euryarchaeota	S	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SX3_k127_1500049_0	1379698.RBG1_1C00001G0655	3.041e-121	397.0	COG0380@1|root,COG0380@2|Bacteria,2NPDG@2323|unclassified Bacteria	2|Bacteria	G	Glycosyltransferase family 20	otsA	-	2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135	ko:K00697,ko:K13057,ko:K20436	ko00500,ko00525,ko01100,ko01130,map00500,map00525,map01100,map01130	M00815	R02737,R08946,R10525,R11239,R11250,R11306,R11497	RC00005,RC00049,RC02748,RC03400,RC03401	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT20,GT4	-	Glyco_transf_20
SX3_k127_1500302_0	1379698.RBG1_1C00001G0356	2.527e-66	248.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria	2|Bacteria	EG	Protein of unknown function (DUF2723)	-	-	-	ko:K16928	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.33	-	-	DUF2723,QueT
SX3_k127_1500455_2	644282.Deba_3105	4.05e-48	183.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3,DUF1992,GNAT_acetyltran
SX3_k127_1500455_3	1313421.JHBV01000029_gene1869	1.322e-39	163.0	COG0726@1|root,COG0726@2|Bacteria,4NPJX@976|Bacteroidetes	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SX3_k127_1500455_0	330214.NIDE3974	1.289e-137	456.0	COG1012@1|root,COG1012@2|Bacteria,3J0YN@40117|Nitrospirae	40117|Nitrospirae	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SX3_k127_1500455_1	742817.HMPREF9449_00800	1.183e-58	210.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,2FNQV@200643|Bacteroidia,22WQA@171551|Porphyromonadaceae	976|Bacteroidetes	E	Peptidase family M3	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SX3_k127_1502455_2	880072.Desac_0600	2.132e-06	59.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,2MQC4@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409	Glycos_transf_4,MraY_sig1
SX3_k127_1502455_0	1123261.AXDW01000010_gene417	1.807e-71	256.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1X3IV@135614|Xanthomonadales	135614|Xanthomonadales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SX3_k127_1502455_3	351348.Maqu_2456	1.192e-05	52.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,464UU@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008766,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0047480,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iB21_1397.B21_00086,iEC042_1314.EC042_0087,iEC55989_1330.EC55989_0082,iECBD_1354.ECBD_3531,iECB_1328.ECB_00087,iECD_1391.ECD_00087,iECIAI1_1343.ECIAI1_0085,iECO103_1326.ECO103_0088,iECO111_1330.ECO111_0089,iECO26_1355.ECO26_0089,iECSE_1348.ECSE_0088,iECW_1372.ECW_m0085,iEKO11_1354.EKO11_3828,iEcE24377_1341.EcE24377A_0088,iEcHS_1320.EcHS_A0092,iEcolC_1368.EcolC_3571,iSBO_1134.SBO_0074,iSSON_1240.SSON_0094,iSbBS512_1146.SbBS512_E0079,iUMNK88_1353.UMNK88_86,iWFL_1372.ECW_m0085,iYL1228.KPN_00090	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SX3_k127_1502455_1	243924.LT42_15925	2.946e-09	59.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	iECO103_1326.ECO103_0087,iECO111_1330.ECO111_0088,iECW_1372.ECW_m0084,iEKO11_1354.EKO11_3829,iWFL_1372.ECW_m0084,ic_1306.c0103	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SX3_k127_150310_0	1047013.AQSP01000130_gene1851	6.789e-68	248.0	COG1453@1|root,COG1453@2|Bacteria,2NNZZ@2323|unclassified Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
SX3_k127_150310_2	565034.BHWA1_02614	5.28e-14	80.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2,Thioredoxin_7
SX3_k127_150310_1	1047013.AQSP01000140_gene2494	6.083e-66	244.0	COG2234@1|root,COG2234@2|Bacteria,2NRCG@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SX3_k127_150310_3	1408473.JHXO01000003_gene2579	2.235e-13	81.0	COG2220@1|root,COG2220@2|Bacteria,4NVGR@976|Bacteroidetes	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SX3_k127_1506836_0	247490.KSU1_C0449	4.886e-110	376.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
SX3_k127_151246_1	1122603.ATVI01000005_gene3501	1.58e-64	243.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SZ6C@1236|Gammaproteobacteria,1XCCV@135614|Xanthomonadales	1236|Gammaproteobacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_19,TPR_2,TPR_8
SX3_k127_151246_0	96561.Dole_3137	1.033e-102	342.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42NJU@68525|delta/epsilon subdivisions,2WKA6@28221|Deltaproteobacteria,2MJK5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
SX3_k127_1515402_0	370438.PTH_1492	3.483e-67	245.0	COG1035@1|root,COG1145@1|root,COG1035@2|Bacteria,COG1145@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	CCG,Cytochrome_B,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4,Fer4_7,Fer4_8,FlpD,FrhB_FdhB_C,FrhB_FdhB_N,LdpA_C
SX3_k127_152101_0	1379698.RBG1_1C00001G1488	3.487e-123	404.0	COG0484@1|root,COG0484@2|Bacteria,2NNNG@2323|unclassified Bacteria	2|Bacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SX3_k127_153806_0	767817.Desgi_0793	2.384e-199	649.0	COG1148@1|root,COG1148@2|Bacteria,1V5YJ@1239|Firmicutes,248CC@186801|Clostridia,260ZH@186807|Peptococcaceae	186801|Clostridia	C	binding domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
SX3_k127_153806_1	767817.Desgi_0792	1.074e-125	409.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,26166@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Pyr_redox_2
SX3_k127_1538888_1	443218.AS9A_1719	1.584e-09	70.0	COG1621@1|root,COG1621@2|Bacteria,2H3S0@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl hydrolase family 32	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32N
SX3_k127_1538888_0	459349.CLOAM0815	2.541e-13	81.0	COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,2NREM@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K07004,ko:K09955	-	-	-	-	ko00000	-	-	-	Big_4,FTP,FlgD_ig,Laminin_G_3,PA,Peptidase_M36
SX3_k127_1551573_0	483219.LILAB_06375	2.891e-11	76.0	2A461@1|root,30SR2@2|Bacteria,1PC3D@1224|Proteobacteria,433A7@68525|delta/epsilon subdivisions,2WXTE@28221|Deltaproteobacteria,2YW5Q@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_1551573_1	67356.KL575607_gene8869	6.135e-05	55.0	COG1652@1|root,COG1652@2|Bacteria,2ID9X@201174|Actinobacteria	201174|Actinobacteria	D	Transglycosylase-like domain	-	-	-	ko:K21687,ko:K21688	-	-	-	-	ko00000	-	GH23	-	LysM,Transglycosylas
SX3_k127_156517_0	330214.NIDE3016	1.157e-117	385.0	COG1209@1|root,COG1209@2|Bacteria,3J0KX@40117|Nitrospirae	40117|Nitrospirae	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SX3_k127_156517_2	357808.RoseRS_1416	3.496e-61	221.0	COG1091@1|root,COG1091@2|Bacteria,2G6NS@200795|Chloroflexi,375G0@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SX3_k127_156517_1	56780.SYN_00576	6.472e-68	234.0	COG1898@1|root,COG1898@2|Bacteria,1RGRQ@1224|Proteobacteria,42RZA@68525|delta/epsilon subdivisions,2WNBP@28221|Deltaproteobacteria,2MRPI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	WxcM-like, C-terminal	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SX3_k127_156517_3	247490.KSU1_C1608	6.795e-31	128.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SX3_k127_1573043_3	330214.NIDE2733	8e-23	107.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
SX3_k127_1573043_1	1480694.DC28_07580	4.873e-87	302.0	COG0167@1|root,COG0167@2|Bacteria,2J972@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.1.1,1.3.98.1	ko:K00226,ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01867,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SX3_k127_1573043_2	1254432.SCE1572_09515	4.88e-44	164.0	COG3005@1|root,COG3005@2|Bacteria,1N0I4@1224|Proteobacteria,42R1B@68525|delta/epsilon subdivisions,2WSF5@28221|Deltaproteobacteria,2Z0Q9@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c nitrite reductase	-	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
SX3_k127_1573043_0	926550.CLDAP_24970	3.669e-183	584.0	COG3303@1|root,COG3303@2|Bacteria,2G5UX@200795|Chloroflexi	200795|Chloroflexi	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
SX3_k127_1573043_4	1121920.AUAU01000013_gene1695	9.727e-10	62.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,3Y2WK@57723|Acidobacteria	57723|Acidobacteria	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1
SX3_k127_1579168_0	1267533.KB906733_gene3429	1.101e-109	360.0	COG0468@1|root,COG0468@2|Bacteria,3Y3Y1@57723|Acidobacteria,2JHU1@204432|Acidobacteriia	204432|Acidobacteriia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SX3_k127_1631687_1	234267.Acid_3225	2.87e-13	73.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_8,Trans_reg_C
SX3_k127_1631687_0	1379698.RBG1_1C00001G1616	1.457e-142	463.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
SX3_k127_1633940_0	1123008.KB905701_gene2236	9.32e-96	322.0	COG4690@1|root,COG4690@2|Bacteria,4NE03@976|Bacteroidetes,2FPSX@200643|Bacteroidia,22WBK@171551|Porphyromonadaceae	976|Bacteroidetes	M	Dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
SX3_k127_1640197_0	880073.Calab_1549	3.024e-209	682.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SX3_k127_1646816_0	401053.AciPR4_0424	2.444e-67	243.0	COG2267@1|root,COG2267@2|Bacteria,3Y9CQ@57723|Acidobacteria,2JP6J@204432|Acidobacteriia	204432|Acidobacteriia	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_1646816_1	1125863.JAFN01000001_gene3327	3.777e-37	146.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SX3_k127_1653178_0	401053.AciPR4_2842	5.208e-34	139.0	COG1807@1|root,COG1807@2|Bacteria,3Y2T0@57723|Acidobacteria,2JIGT@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_1653178_1	1210884.HG799467_gene13174	8.811e-29	122.0	COG1807@1|root,COG1807@2|Bacteria,2IZFZ@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SX3_k127_1666138_0	1047013.AQSP01000098_gene2568	1.572e-137	465.0	COG1042@1|root,COG1042@2|Bacteria,2NNW5@2323|unclassified Bacteria	2|Bacteria	C	synthetase (ADP forming), alpha	-	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SX3_k127_1683241_0	398525.KB900701_gene6862	8.518e-06	51.0	COG0071@1|root,COG0071@2|Bacteria,1N0RH@1224|Proteobacteria,2UE1E@28211|Alphaproteobacteria,3JYYY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Hsp20/alpha crystallin family	MA20_45160	-	-	-	-	-	-	-	-	-	-	-	HSP20
SX3_k127_1689016_1	909663.KI867151_gene2967	2.036e-31	137.0	COG4191@1|root,COG4191@2|Bacteria,1PGQG@1224|Proteobacteria,439Y9@68525|delta/epsilon subdivisions,2X1VH@28221|Deltaproteobacteria,2MRRE@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SX3_k127_1689016_0	909663.KI867151_gene2967	1.141e-47	176.0	COG4191@1|root,COG4191@2|Bacteria,1PGQG@1224|Proteobacteria,439Y9@68525|delta/epsilon subdivisions,2X1VH@28221|Deltaproteobacteria,2MRRE@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SX3_k127_1692885_2	694427.Palpr_0853	8.518e-25	105.0	COG2223@1|root,COG2223@2|Bacteria,4NFEU@976|Bacteroidetes,2FNE8@200643|Bacteroidia,22WXE@171551|Porphyromonadaceae	976|Bacteroidetes	P	Transporter, major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SX3_k127_1692885_1	643867.Ftrac_0696	1.59e-26	115.0	COG1331@1|root,COG1331@2|Bacteria,4PKPW@976|Bacteroidetes,47XYJ@768503|Cytophagia	976|Bacteroidetes	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7
SX3_k127_1692885_0	56780.SYN_00886	8.507e-67	235.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria,2MQH8@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Phosphofructokinase	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SX3_k127_1695033_1	1124780.ANNU01000048_gene2161	4.069e-71	261.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,47MII@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SX3_k127_1695033_0	761193.Runsl_2215	1.273e-74	257.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,47KCE@768503|Cytophagia	976|Bacteroidetes	T	PFAM response regulator receiver	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SX3_k127_1695033_2	644282.Deba_2754	9.682e-08	56.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42R8Z@68525|delta/epsilon subdivisions,2WMXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
SX3_k127_1715253_1	269799.Gmet_1640	1.781e-52	189.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria,43TVR@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SX3_k127_1715253_2	1121104.AQXH01000001_gene1969	1.034e-28	127.0	2BT60@1|root,32NAZ@2|Bacteria,4P6EN@976|Bacteroidetes,1IZF8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_1715253_5	1232437.KL662064_gene4028	3.527e-06	58.0	COG2259@1|root,COG2259@2|Bacteria,1RIFW@1224|Proteobacteria,42SRS@68525|delta/epsilon subdivisions,2WPBA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM DoxX family protein	-	-	-	-	-	-	-	-	-	-	-	-	MauE
SX3_k127_1715253_3	269799.Gmet_3018	5.839e-17	87.0	COG0607@1|root,COG0607@2|Bacteria,1N256@1224|Proteobacteria,42TIJ@68525|delta/epsilon subdivisions,2WQHB@28221|Deltaproteobacteria,43V99@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SX3_k127_1715253_0	1148.1652843	3.902e-68	238.0	COG0177@1|root,COG0177@2|Bacteria,1G1VI@1117|Cyanobacteria,1H4XS@1142|Synechocystis	1117|Cyanobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SX3_k127_1720565_2	570952.ATVH01000015_gene1311	4.249e-15	87.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2TVZH@28211|Alphaproteobacteria,2JQ60@204441|Rhodospirillales	204441|Rhodospirillales	P	Mg2 and Co2 transporter CorB	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SX3_k127_1720565_0	1449126.JQKL01000073_gene3045	1.114e-72	269.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,268U9@186813|unclassified Clostridiales	186801|Clostridia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SX3_k127_1720565_3	1121013.P873_02890	0.0002942	53.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1X5DD@135614|Xanthomonadales	135614|Xanthomonadales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
SX3_k127_1720565_1	269799.Gmet_3541	1.451e-37	147.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,43UVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM OmpA MotB domain protein	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SX3_k127_1728372_0	868595.Desca_0706	2.609e-52	192.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,25ZZS@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SX3_k127_1728372_1	1297581.H919_06766	1.709e-33	133.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,21WVH@150247|Anoxybacillus	91061|Bacilli	D	Actin	mbl	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SX3_k127_1728414_0	667014.Thein_1636	6.478e-106	366.0	COG1022@1|root,COG1022@2|Bacteria,2GIQW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SX3_k127_1728414_2	1379698.RBG1_1C00001G1024	1.532e-29	131.0	COG0382@1|root,COG0382@2|Bacteria,2NRJ9@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	-	-	2.5.1.133,2.5.1.39,2.5.1.62	ko:K03179,ko:K04040	ko00130,ko00860,ko01100,ko01110,map00130,map00860,map01100,map01110	M00117	R05000,R05615,R06284,R09067,R11514,R11517	RC00020,RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SX3_k127_1728414_1	243231.GSU1437	1.653e-54	201.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42MBR@68525|delta/epsilon subdivisions,2WJ0Z@28221|Deltaproteobacteria,43SFX@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1238	Peptidase_M48,TPR_14,TPR_16,TPR_19
SX3_k127_1735313_1	1123368.AUIS01000004_gene259	2.309e-83	289.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,2NCI8@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SX3_k127_1735313_0	401526.TcarDRAFT_0036	3.023e-119	401.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4H31K@909932|Negativicutes	909932|Negativicutes	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SX3_k127_1735313_2	1134912.AJTV01000007_gene1104	4.884e-15	78.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2U591@28211|Alphaproteobacteria,36Y5P@31993|Methylocystaceae	28211|Alphaproteobacteria	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768,ko:K09565	ko01503,ko04020,ko04022,ko04217,ko05012,ko05016,ko05145,map01503,map04020,map04022,map04217,map05012,map05016,map05145	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SX3_k127_1748598_0	439235.Dalk_3355	1.366e-07	63.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2WRUR@28221|Deltaproteobacteria,2MP10@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
SX3_k127_175905_0	398767.Glov_1372	1.37e-68	238.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SX3_k127_175905_2	1379698.RBG1_1C00001G1570	5.967e-49	179.0	COG0100@1|root,COG0100@2|Bacteria,2NPCN@2323|unclassified Bacteria	2|Bacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SX3_k127_175905_3	477974.Daud_0250	1.105e-41	156.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,261QX@186807|Peptococcaceae	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SX3_k127_175905_5	1121439.dsat_2551	2.924e-13	69.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2WSYK@28221|Deltaproteobacteria,2MDXC@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SX3_k127_175905_4	1232437.KL662001_gene4551	4.888e-32	125.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MKKE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SX3_k127_175905_1	1120973.AQXL01000112_gene1094	1.488e-62	218.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,277XD@186823|Alicyclobacillaceae	91061|Bacilli	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SX3_k127_1759688_1	944479.JQLX01000010_gene518	3.372e-43	177.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,2M703@213113|Desulfurellales	28221|Deltaproteobacteria	E	Dihydrodipicolinate reductase, C-terminus	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SX3_k127_1759688_0	316067.Geob_1130	2.055e-97	327.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,43SVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	EM	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SX3_k127_1764299_0	192952.MM_0178	0.0005655	50.0	COG0457@1|root,arCOG03038@2157|Archaea,2XUNW@28890|Euryarchaeota,2NAF9@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
SX3_k127_1770574_0	1499967.BAYZ01000034_gene1067	1.931e-103	350.0	COG0845@1|root,COG0845@2|Bacteria,2NPBH@2323|unclassified Bacteria	2|Bacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	macA_1	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
SX3_k127_1770574_1	1379270.AUXF01000001_gene1950	2.585e-91	325.0	COG1136@1|root,COG1136@2|Bacteria,1ZUSK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SX3_k127_1770574_2	517418.Ctha_0502	1.494e-07	62.0	COG0577@1|root,COG0577@2|Bacteria,1FDCY@1090|Chlorobi	1090|Chlorobi	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
SX3_k127_1776122_0	1379698.RBG1_1C00001G1613	9e-64	226.0	COG0515@1|root,COG0515@2|Bacteria,2NPFQ@2323|unclassified Bacteria	2|Bacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,PEGA,Pkinase
SX3_k127_1776122_1	867845.KI911784_gene2851	3.967e-45	179.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi,375HP@32061|Chloroflexia	32061|Chloroflexia	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SX3_k127_1776122_2	326427.Cagg_2459	3.437e-07	59.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Peptidase_C11
SX3_k127_1785384_1	1123277.KB893243_gene325	2.255e-31	126.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47KZX@768503|Cytophagia	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SX3_k127_1785384_0	1123073.KB899241_gene3242	3.311e-50	205.0	COG1572@1|root,COG3210@1|root,COG3391@1|root,COG4932@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,1QUXB@1224|Proteobacteria,1SUAH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_1798672_0	909663.KI867149_gene3375	1.885e-176	560.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2MQB6@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SX3_k127_1798672_1	644966.Tmar_0664	0.0001116	51.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,3WD15@538999|Clostridiales incertae sedis	186801|Clostridia	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
SX3_k127_1805546_1	945713.IALB_2290	7.375e-10	66.0	2AQ71@1|root,31FCR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_1805546_2	880073.Calab_0041	7.058e-09	68.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
SX3_k127_1805546_0	867845.KI911784_gene3418	4.272e-10	72.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Arylsulfotran_2,Arylsulfotrans
SX3_k127_1809587_1	1033743.CAES01000002_gene1777	9.059e-109	369.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,4HAZ0@91061|Bacilli,26VCR@186822|Paenibacillaceae	91061|Bacilli	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
SX3_k127_1809587_2	402777.KB235898_gene5099	2.859e-16	94.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2,TPR_1,TPR_8
SX3_k127_1809587_0	555079.Toce_0627	3.742e-126	420.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,42FVS@68295|Thermoanaerobacterales	186801|Clostridia	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	GltP	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
SX3_k127_181231_1	38654.XP_006029733.1	0.0002554	50.0	COG2940@1|root,KOG1082@2759|Eukaryota,38GXX@33154|Opisthokonta,3BA3A@33208|Metazoa,3D0GH@33213|Bilateria,485RE@7711|Chordata,48YDC@7742|Vertebrata	33208|Metazoa	B	Histone-lysine N-methyltransferase	EHMT1	GO:0000122,GO:0002039,GO:0002165,GO:0002682,GO:0002697,GO:0002831,GO:0003008,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005700,GO:0005705,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007444,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007614,GO:0007616,GO:0007626,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008345,GO:0008757,GO:0009719,GO:0009725,GO:0009755,GO:0009791,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010558,GO:0010564,GO:0010604,GO:0010605,GO:0010629,GO:0010638,GO:0010720,GO:0010769,GO:0010770,GO:0010948,GO:0010975,GO:0010976,GO:0014070,GO:0016043,GO:0016278,GO:0016279,GO:0016569,GO:0016570,GO:0016571,GO:0016604,GO:0016740,GO:0016741,GO:0018022,GO:0018024,GO:0018026,GO:0018027,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0019904,GO:0022008,GO:0022603,GO:0022604,GO:0023052,GO:0030154,GO:0030518,GO:0030522,GO:0030537,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031344,GO:0031346,GO:0031347,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0032101,GO:0032259,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032870,GO:0033043,GO:0033044,GO:0033993,GO:0034641,GO:0034968,GO:0035075,GO:0035076,GO:0035220,GO:0035295,GO:0036211,GO:0036314,GO:0036315,GO:0042054,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043401,GO:0043412,GO:0043414,GO:0043900,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044728,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045786,GO:0045892,GO:0045934,GO:0045995,GO:0046483,GO:0046958,GO:0046959,GO:0046974,GO:0046976,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048699,GO:0048731,GO:0048814,GO:0048856,GO:0048869,GO:0050688,GO:0050767,GO:0050769,GO:0050773,GO:0050775,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050890,GO:0050896,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051276,GO:0051567,GO:0051570,GO:0051574,GO:0051716,GO:0051726,GO:0051960,GO:0051962,GO:0060255,GO:0060284,GO:0060429,GO:0061647,GO:0065007,GO:0070013,GO:0070316,GO:0070317,GO:0070734,GO:0070742,GO:0070887,GO:0071310,GO:0071383,GO:0071390,GO:0071396,GO:0071407,GO:0071495,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0090304,GO:0097305,GO:0097306,GO:0098687,GO:0120035,GO:0140096,GO:1900006,GO:1900109,GO:1900111,GO:1901360,GO:1901564,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1902275,GO:1902679,GO:1903506,GO:1903507,GO:1905269,GO:2000026,GO:2000112,GO:2000113,GO:2001141,GO:2001252	2.1.1.43	ko:K11420	ko00310,ko04211,map00310,map04211	-	R03875,R03938,R04866,R04867	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000,ko03036	-	-	-	Ank_2,Ank_4,Pre-SET,SET
SX3_k127_181231_0	243231.GSU1613	9.416e-81	277.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,43TKZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	endonuclease III	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
SX3_k127_1813966_0	521674.Plim_3586	2.653e-12	77.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,2IZUV@203682|Planctomycetes	203682|Planctomycetes	H	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
SX3_k127_1821552_2	1121930.AQXG01000001_gene1525	5.395e-30	131.0	COG2067@1|root,COG2067@2|Bacteria,4NWE8@976|Bacteroidetes,1IYUI@117747|Sphingobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
SX3_k127_1821552_1	1379698.RBG1_1C00001G0342	1.595e-40	160.0	COG2908@1|root,COG2908@2|Bacteria,2NPKW@2323|unclassified Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	lpxH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iE2348C_1286.E2348C_0457	Metallophos,Metallophos_2
SX3_k127_1821552_0	1379698.RBG1_1C00001G0598	1.694e-100	336.0	COG0568@1|root,COG0568@2|Bacteria,2NNY9@2323|unclassified Bacteria	2|Bacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SX3_k127_1821552_3	309807.SRU_2168	1.44e-10	71.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,1FIN5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SX3_k127_1822127_0	237368.SCABRO_03002	2.303e-13	75.0	COG2839@1|root,COG2839@2|Bacteria,2J3BV@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF456)	-	-	-	-	-	-	-	-	-	-	-	-	DUF456
SX3_k127_1822127_1	309807.SRU_0655	8.07e-06	59.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,1FJ03@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SX3_k127_1867119_0	562970.Btus_0661	1.823e-210	667.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,2783N@186823|Alicyclobacillaceae	91061|Bacilli	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SX3_k127_1868885_0	177437.HRM2_00040	1.923e-06	54.0	COG0810@1|root,COG0810@2|Bacteria,1R4VE@1224|Proteobacteria,42SEP@68525|delta/epsilon subdivisions,2WPUA@28221|Deltaproteobacteria,2MK7X@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SX3_k127_1872029_1	77635.BISU_0167	1.219e-05	57.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4CZK5@85004|Bifidobacteriales	201174|Actinobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SX3_k127_1872029_0	247490.KSU1_C0449	8.864e-34	135.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
SX3_k127_1875390_0	204669.Acid345_2243	1.721e-121	396.0	COG0436@1|root,COG0436@2|Bacteria,3Y3DG@57723|Acidobacteria,2JMAM@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SX3_k127_1895137_1	498761.HM1_2773	1.595e-08	62.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia	186801|Clostridia	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
SX3_k127_1895137_0	945713.IALB_2034	6.592e-116	383.0	COG0733@1|root,COG0733@2|Bacteria	2|Bacteria	S	neurotransmitter:sodium symporter activity	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
SX3_k127_1898557_0	716928.AJQT01000042_gene3098	9.013e-69	244.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,2U3N3@28211|Alphaproteobacteria,4B738@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SX3_k127_190332_0	1123228.AUIH01000092_gene553	1.323e-07	63.0	COG3210@1|root,COG3210@2|Bacteria,1QZXD@1224|Proteobacteria,1T4BM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_1905737_1	338966.Ppro_2253	3.61e-54	213.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,43T3H@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Pterin binding enzyme	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SX3_k127_1905737_0	1191523.MROS_0436	3.055e-126	413.0	COG0465@1|root,COG0465@2|Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SX3_k127_1913585_1	158190.SpiGrapes_2237	1.079e-13	78.0	COG2197@1|root,COG2197@2|Bacteria,2J9AC@203691|Spirochaetes	203691|Spirochaetes	KT	transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SX3_k127_1913585_0	1304865.JAGF01000001_gene1545	1.083e-28	124.0	COG1266@1|root,COG1266@2|Bacteria,2INQ6@201174|Actinobacteria	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SX3_k127_1923164_1	272562.CA_C2798	6.067e-30	122.0	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,36EGZ@31979|Clostridiaceae	186801|Clostridia	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.6.99.1	ko:K00354	-	-	R00282	RC00001	ko00000,ko01000	-	-	-	Oxidored_FMN
SX3_k127_1923164_0	644282.Deba_2234	6.424e-191	602.0	COG0191@1|root,COG0191@2|Bacteria,1NMAK@1224|Proteobacteria,42NPW@68525|delta/epsilon subdivisions,2WIMN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Ketose-bisphosphate aldolase, class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
SX3_k127_1932187_1	1128421.JAGA01000002_gene1359	1.112e-27	116.0	COG0520@1|root,COG0520@2|Bacteria,2NP4B@2323|unclassified Bacteria	2|Bacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SX3_k127_1932187_2	1121930.AQXG01000002_gene2126	4.077e-08	65.0	COG1649@1|root,COG1649@2|Bacteria,4NI9V@976|Bacteroidetes,1IPVJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
SX3_k127_1932187_0	1392490.JHZX01000001_gene2181	8.385e-28	127.0	COG2234@1|root,COG3291@1|root,COG2234@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.8,3.4.11.10	ko:K01181,ko:K05994	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,DUF285,F5_F8_type_C,LRR_5,Peptidase_M28
SX3_k127_1954877_3	1168034.FH5T_20550	5.415e-79	269.0	COG2223@1|root,COG2223@2|Bacteria,4NHX9@976|Bacteroidetes,2FZ04@200643|Bacteroidia	976|Bacteroidetes	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
SX3_k127_1954877_2	335541.Swol_1787	6.536e-144	473.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,42KH2@68298|Syntrophomonadaceae	186801|Clostridia	H	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SX3_k127_1954877_1	1321778.HMPREF1982_00035	2.067e-153	506.0	COG2511@1|root,COG2511@2|Bacteria,1UPG0@1239|Firmicutes,25HFT@186801|Clostridia	186801|Clostridia	J	GatB/GatE catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GatB_N
SX3_k127_1954877_0	1047013.AQSP01000142_gene241	5.763e-221	698.0	COG0252@1|root,COG0252@2|Bacteria,2NPMK@2323|unclassified Bacteria	2|Bacteria	EJ	Asparaginase	ansA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
SX3_k127_1954877_4	877455.Metbo_1956	5.146e-15	89.0	COG2244@1|root,arCOG02209@2157|Archaea	2157|Archaea	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
SX3_k127_195987_0	1197477.IA57_07775	7.798e-51	201.0	COG1073@1|root,COG1073@2|Bacteria,4PMNT@976|Bacteroidetes,1HZRQ@117743|Flavobacteriia	976|Bacteroidetes	N	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF676,PGAP1
SX3_k127_1989529_0	318464.IO99_03555	3.071e-35	147.0	COG0400@1|root,COG0400@2|Bacteria,1V36F@1239|Firmicutes,25D83@186801|Clostridia,36T2B@31979|Clostridiaceae	186801|Clostridia	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_1989529_1	1122990.BAJH01000033_gene2617	3.15e-31	128.0	2C0TM@1|root,32UWC@2|Bacteria,4NSYE@976|Bacteroidetes,2FTDD@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
SX3_k127_2004296_0	96561.Dole_0807	1.578e-92	313.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,43BPM@68525|delta/epsilon subdivisions,2X70W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM secretion protein HlyD family protein	ybhG	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SX3_k127_2011032_0	880073.Calab_2431	1.773e-126	421.0	COG0624@1|root,COG0624@2|Bacteria,2NQ4M@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M20/M25/M40	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SX3_k127_2011032_1	706587.Desti_3270	6.305e-98	339.0	COG2202@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SX3_k127_2011032_2	880073.Calab_3349	2.579e-30	135.0	COG0457@1|root,COG0457@2|Bacteria	880073.Calab_3349|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2013835_0	1126627.BAWE01000004_gene2562	3.028e-82	284.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQJC@28211|Alphaproteobacteria,3JU9K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	MA20_01205	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SX3_k127_2013835_1	278963.ATWD01000002_gene352	9.973e-37	152.0	COG1236@1|root,COG1236@2|Bacteria,3Y6U0@57723|Acidobacteria,2JMFJ@204432|Acidobacteriia	204432|Acidobacteriia	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
SX3_k127_2016339_1	1304885.AUEY01000016_gene3032	6.725e-17	89.0	COG1633@1|root,COG1633@2|Bacteria,1RGYD@1224|Proteobacteria,42T5E@68525|delta/epsilon subdivisions,2WPKD@28221|Deltaproteobacteria,2MKDK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SX3_k127_2016339_0	882.DVU_3184	3.263e-24	102.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,42VC4@68525|delta/epsilon subdivisions,2WRDM@28221|Deltaproteobacteria,2MD4A@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Rubredoxin-type Fe(Cys)4 protein	rub	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	Rubredoxin
SX3_k127_2016339_3	1167006.UWK_00883	3.245e-10	65.0	COG1592@1|root,COG4244@1|root,COG1592@2|Bacteria,COG4244@2|Bacteria,1RGN3@1224|Proteobacteria,42S4Q@68525|delta/epsilon subdivisions,2WNKZ@28221|Deltaproteobacteria,2MJV6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2016339_4	529709.PYCH_09750	0.0004458	49.0	COG1633@1|root,arCOG01103@2157|Archaea,2Y1BE@28890|Euryarchaeota,243JF@183968|Thermococci	183968|Thermococci	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SX3_k127_2016339_2	383372.Rcas_2849	1.449e-10	66.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,375DF@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,SpoIIE
SX3_k127_2019129_1	118005.AWNK01000001_gene2002	2.169e-05	55.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6
SX3_k127_2019129_0	562970.Btus_2178	5.349e-132	432.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,2781C@186823|Alicyclobacillaceae	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SX3_k127_2028400_2	697284.ERIC2_c02420	2.385e-44	167.0	COG1387@1|root,COG1387@2|Bacteria,1UZ0M@1239|Firmicutes,4IQT7@91061|Bacilli,26RD1@186822|Paenibacillaceae	91061|Bacilli	E	Histidinol phosphatase	hisJ1	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP,PHP_C
SX3_k127_2028400_1	1131814.JAFO01000001_gene276	4.944e-104	354.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,2TQSJ@28211|Alphaproteobacteria,3F0A4@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	AIR synthase related protein, C-terminal domain	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
SX3_k127_2028400_0	1382306.JNIM01000001_gene189	2.377e-114	386.0	COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
SX3_k127_2039589_0	313606.M23134_01115	8.679e-47	181.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,4NHRI@976|Bacteroidetes,47KP6@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SX3_k127_2050777_0	1254432.SCE1572_05370	1.15e-79	286.0	COG0515@1|root,COG1672@1|root,COG2319@1|root,COG0515@2|Bacteria,COG1672@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,4328Z@68525|delta/epsilon subdivisions,2X7NM@28221|Deltaproteobacteria,2YXMY@29|Myxococcales	28221|Deltaproteobacteria	T	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,Pkinase,WD40
SX3_k127_2058389_0	582515.KR51_00025500	7.384e-11	72.0	COG0697@1|root,COG0697@2|Bacteria,1G08M@1117|Cyanobacteria	1117|Cyanobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SX3_k127_2060215_5	1288963.ADIS_3461	3.016e-14	79.0	2EIT9@1|root,33CIJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2060215_1	1298880.AUEV01000010_gene2846	3.29e-49	183.0	COG4912@1|root,COG4912@2|Bacteria	2|Bacteria	L	Dna alkylation repair	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SX3_k127_2060215_0	1122929.KB908220_gene2756	4.7e-56	197.0	COG1917@1|root,COG1917@2|Bacteria,1RGXQ@1224|Proteobacteria,2U7IF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel domain protein	MA20_27600	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2060215_4	1121324.CLIT_11c02670	2.402e-28	119.0	2E74N@1|root,331P2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2060215_2	234267.Acid_1797	4.094e-41	164.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2,SnoaL_4
SX3_k127_2060215_6	32049.SYNPCC7002_A1133	3.03e-07	57.0	COG1637@1|root,COG1637@2|Bacteria,1GPRG@1117|Cyanobacteria,1H3QN@1129|Synechococcus	1117|Cyanobacteria	L	Endonuclease NucS	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	NucS
SX3_k127_2060215_3	1191523.MROS_1662	5.428e-29	127.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	-	R02029,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SX3_k127_2060215_7	386456.JQKN01000014_gene3103	3.196e-06	50.0	COG0589@1|root,arCOG02053@2157|Archaea,2XXRS@28890|Euryarchaeota	28890|Euryarchaeota	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SX3_k127_207440_0	644966.Tmar_1223	8.447e-100	339.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WCF6@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SX3_k127_2076327_0	404380.Gbem_2447	4.401e-151	497.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,43TE2@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM AAA ATPase central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SX3_k127_2076327_1	290397.Adeh_1640	3.284e-77	269.0	COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,42M34@68525|delta/epsilon subdivisions,2WKJ6@28221|Deltaproteobacteria,2YX5K@29|Myxococcales	28221|Deltaproteobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SX3_k127_2084863_1	1121472.AQWN01000003_gene1557	1.348e-35	139.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,260NW@186807|Peptococcaceae	186801|Clostridia	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
SX3_k127_2084863_2	1035308.AQYY01000001_gene3259	2.715e-24	116.0	COG1266@1|root,COG1266@2|Bacteria,1VMEK@1239|Firmicutes,24V6I@186801|Clostridia	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SX3_k127_2084863_3	1123073.KB899241_gene2408	1.686e-09	69.0	2CKE6@1|root,32ZEV@2|Bacteria,1NBRM@1224|Proteobacteria,1SCY3@1236|Gammaproteobacteria,1X8E5@135614|Xanthomonadales	135614|Xanthomonadales	S	Family of unknown function (DUF5329)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5329
SX3_k127_2084863_4	1121875.KB907547_gene3432	5.419e-07	54.0	28WBK@1|root,2ZIC0@2|Bacteria,4P7B5@976|Bacteroidetes,1IBE5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2084863_0	1121422.AUMW01000009_gene3340	2.148e-132	425.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,2618A@186807|Peptococcaceae	186801|Clostridia	C	Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
SX3_k127_2092102_0	459349.CLOAM0575	2.103e-54	213.0	COG4412@1|root,COG4412@2|Bacteria,2NPRE@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CarboxypepD_reg,FlgD_ig,Peptidase_M6
SX3_k127_209862_0	1047013.AQSP01000098_gene2571	2.09e-88	304.0	COG3579@1|root,COG3579@2|Bacteria	2|Bacteria	E	homocysteine catabolic process	-	-	3.4.22.40	ko:K01372,ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03032	-	-	-	Peptidase_C1,Peptidase_C1_2
SX3_k127_2106166_0	1379698.RBG1_1C00001G0607	4.857e-133	443.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
SX3_k127_2106166_1	234267.Acid_5940	5.882e-52	193.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SX3_k127_2122833_2	204669.Acid345_1618	6.816e-16	78.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SX3_k127_2122833_1	1232410.KI421418_gene2299	1.2e-64	236.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,43RZY@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	SecD/SecF GG Motif	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SX3_k127_2122833_0	118005.AWNK01000010_gene361	8.533e-70	241.0	COG0342@1|root,COG0342@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SX3_k127_2123812_0	1191523.MROS_1045	7.1e-37	154.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
SX3_k127_2123812_1	671143.DAMO_1099	2.475e-11	65.0	COG0704@1|root,COG1392@1|root,COG0704@2|Bacteria,COG1392@2|Bacteria,2NPPV@2323|unclassified Bacteria	2|Bacteria	P	Protein of unknown function DUF47	phoU	GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039,ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU,PhoU_div
SX3_k127_2125649_0	1487923.DP73_09880	3.257e-36	156.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
SX3_k127_2125649_2	215358.XP_010745285.1	0.0009414	53.0	COG0457@1|root,KOG1124@2759|Eukaryota,38CY4@33154|Opisthokonta,3BAFG@33208|Metazoa,3CV6Z@33213|Bilateria,480W8@7711|Chordata,4967I@7742|Vertebrata,49V00@7898|Actinopterygii	33208|Metazoa	S	Transmembrane and tetratricopeptide repeat containing 3	TMTC3	GO:0001763,GO:0002009,GO:0003401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006950,GO:0007275,GO:0008150,GO:0009653,GO:0009791,GO:0009887,GO:0009888,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0012505,GO:0019222,GO:0030154,GO:0030162,GO:0030323,GO:0030324,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0033554,GO:0034976,GO:0035239,GO:0035295,GO:0040007,GO:0042176,GO:0042692,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045732,GO:0045862,GO:0048286,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048729,GO:0048731,GO:0048747,GO:0048754,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051146,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051716,GO:0055001,GO:0055002,GO:0060255,GO:0060425,GO:0060429,GO:0060441,GO:0060447,GO:0060541,GO:0060560,GO:0060562,GO:0060602,GO:0061061,GO:0061136,GO:0061138,GO:0065007,GO:0080090,GO:1901800,GO:1903050,GO:1903052,GO:1903362,GO:1903364	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
SX3_k127_2125649_1	880073.Calab_0143	4.533e-05	57.0	COG4219@1|root,COG4219@2|Bacteria,2NS3V@2323|unclassified Bacteria	2|Bacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6,DUF4309,DUF5301
SX3_k127_2126553_0	880073.Calab_3115	5.185e-61	226.0	COG3104@1|root,COG3104@2|Bacteria	2|Bacteria	E	oligopeptide transport	dtpD	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	MFS_1,PTR2
SX3_k127_2129042_0	1382306.JNIM01000001_gene330	4.075e-11	66.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SX3_k127_2130986_2	644282.Deba_2839	1.125e-41	155.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.12.1.3,1.6.5.3	ko:K00124,ko:K00335,ko:K18331	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
SX3_k127_2130986_1	429009.Adeg_0158	8.313e-42	160.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24I29@186801|Clostridia,42ICW@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SX3_k127_2130986_0	552811.Dehly_0623	6.485e-42	159.0	COG3383@1|root,COG3383@2|Bacteria,2GAS8@200795|Chloroflexi,34D7W@301297|Dehalococcoidia	301297|Dehalococcoidia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4
SX3_k127_2133594_0	1047013.AQSP01000126_gene2731	1.889e-143	469.0	COG0446@1|root,COG1142@1|root,COG1251@1|root,COG2080@1|root,COG0446@2|Bacteria,COG1142@2|Bacteria,COG1251@2|Bacteria,COG2080@2|Bacteria,2NP2E@2323|unclassified Bacteria	2|Bacteria	C	FAD dependent oxidoreductase	-	-	1.12.5.1,1.2.5.3,1.3.99.16,1.7.1.15	ko:K00205,ko:K00362,ko:K02573,ko:K03518,ko:K05927,ko:K07302	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00530,M00567	R00787,R03015,R08060,R11168,R11743	RC00176,RC00197,RC00323,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2,Fer2_4,Fer2_BFD,Fer4,Fer4_20,Fer4_7,GXGXG,NiFe_hyd_SSU_C,Oxidored_q6,Pyr_redox_2
SX3_k127_2133594_1	384765.SIAM614_23352	1.529e-06	50.0	COG0665@1|root,COG0665@2|Bacteria,1PERE@1224|Proteobacteria,2U1FT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SX3_k127_2137594_1	1121104.AQXH01000004_gene63	1.869e-19	96.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1IWPE@117747|Sphingobacteriia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SX3_k127_2137594_2	307480.IW16_15530	1.231e-14	82.0	COG4783@1|root,COG4783@2|Bacteria,4NJ2X@976|Bacteroidetes,1I05N@117743|Flavobacteriia,3ZT3R@59732|Chryseobacterium	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
SX3_k127_2137594_0	1089547.KB913013_gene3291	4.094e-41	161.0	COG2333@1|root,COG2333@2|Bacteria,4NN5Y@976|Bacteroidetes,47QYX@768503|Cytophagia	976|Bacteroidetes	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SX3_k127_2149862_0	1499967.BAYZ01000173_gene5813	2.998e-143	476.0	COG2304@1|root,COG2304@2|Bacteria,2NPZM@2323|unclassified Bacteria	2|Bacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	FecR,VIT,VWA,VWA_3
SX3_k127_2149862_2	309801.trd_1051	0.0004357	52.0	COG5662@1|root,COG5662@2|Bacteria,2GBGZ@200795|Chloroflexi,27XXW@189775|Thermomicrobia	189775|Thermomicrobia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SX3_k127_2149862_1	1254432.SCE1572_42100	2.619e-30	125.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2YV9U@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SX3_k127_2151277_0	555079.Toce_1695	6.919e-86	300.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SX3_k127_2151277_1	1423321.AS29_16805	2.032e-05	48.0	29SCT@1|root,30DHF@2|Bacteria,1UBAH@1239|Firmicutes,4IMPC@91061|Bacilli,1ZKIZ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2152360_1	861299.J421_3262	4.069e-41	154.0	COG4974@1|root,COG4974@2|Bacteria,1ZTAH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SX3_k127_2152360_0	945713.IALB_1557	1.461e-44	170.0	COG1354@1|root,COG1354@2|Bacteria	2|Bacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SX3_k127_2152543_1	522772.Dacet_0072	3.142e-47	176.0	COG3808@1|root,COG3808@2|Bacteria,2GFAJ@200930|Deferribacteres	200930|Deferribacteres	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SX3_k127_2152543_0	1121015.N789_06030	4.476e-166	529.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1X3NP@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SX3_k127_2154959_0	1340493.JNIF01000003_gene2068	2.021e-157	509.0	COG0358@1|root,COG0358@2|Bacteria	2|Bacteria	L	DNA primase activity	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_2,Toprim_N,zf-CHC2
SX3_k127_2177900_0	1316936.K678_05423	1.126e-74	276.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2JQBN@204441|Rhodospirillales	204441|Rhodospirillales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SX3_k127_2200958_3	644282.Deba_1225	3.23e-14	84.0	COG2172@1|root,COG2204@1|root,COG2172@2|Bacteria,COG2204@2|Bacteria,1PGJ3@1224|Proteobacteria,4315J@68525|delta/epsilon subdivisions,2WWDE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,Response_reg
SX3_k127_2200958_2	861299.J421_3210	1.467e-14	81.0	2F3JX@1|root,33WDB@2|Bacteria,1ZTZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
SX3_k127_2200958_4	398767.Glov_0411	1.232e-06	58.0	2AKQ6@1|root,2ZAYQ@2|Bacteria,1R429@1224|Proteobacteria,42NWN@68525|delta/epsilon subdivisions,2WMKI@28221|Deltaproteobacteria,43V14@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TIGRFAM MJ0042 family finger-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
SX3_k127_2200958_1	309803.CTN_1141	9.513e-56	201.0	COG2316@1|root,COG2316@2|Bacteria,2GCT9@200918|Thermotogae	200918|Thermotogae	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K06951	-	-	-	-	ko00000	-	-	-	HD
SX3_k127_2200958_0	388467.A19Y_3828	1.461e-109	366.0	COG1200@1|root,COG1200@2|Bacteria,1G17H@1117|Cyanobacteria,1H8UT@1150|Oscillatoriales	1117|Cyanobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SX3_k127_2223691_0	459349.CLOAM0061	5.902e-08	66.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	wprA	-	3.1.3.6,3.1.4.16,3.2.1.99	ko:K01119,ko:K06113,ko:K12685,ko:K20276	ko00230,ko00240,ko02024,map00230,map00240,map02024	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	GH43	-	Mucin_bdg,Peptidase_M60,Peptidase_S8,SLH
SX3_k127_2229399_0	1167006.UWK_00772	2.688e-21	104.0	2DS9E@1|root,32VU1@2|Bacteria,1P3D6@1224|Proteobacteria,431R2@68525|delta/epsilon subdivisions,2WW7F@28221|Deltaproteobacteria,2MNTP@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2229937_1	269799.Gmet_2917	4.944e-78	267.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,42QKQ@68525|delta/epsilon subdivisions,2WUIA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
SX3_k127_2229937_0	1304874.JAFY01000007_gene1691	8.145e-100	328.0	COG0369@1|root,COG1151@2|Bacteria,3TA79@508458|Synergistetes	508458|Synergistetes	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
SX3_k127_2238873_1	1324957.K933_16757	5.247e-32	139.0	COG0438@1|root,arCOG01410@2157|Archaea,2XV5R@28890|Euryarchaeota,23USK@183963|Halobacteria	183963|Halobacteria	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SX3_k127_2238873_0	383372.Rcas_0781	2.822e-104	349.0	COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi,3772V@32061|Chloroflexia	32061|Chloroflexia	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SX3_k127_223919_0	498761.HM1_0203	1.065e-51	195.0	COG0611@1|root,COG0611@2|Bacteria,1V0SM@1239|Firmicutes,24J04@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SX3_k127_2247017_2	880073.Calab_2773	3.88e-22	111.0	COG3599@1|root,COG3599@2|Bacteria,2NQ77@2323|unclassified Bacteria	2|Bacteria	D	DivIVA protein	gpsB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04074,ko:K07484	-	-	-	-	ko00000,ko03036	-	-	-	DDE_Tnp_IS66,DivIVA
SX3_k127_2247017_0	264732.Moth_0858	6.431e-55	203.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,42G1Y@68295|Thermoanaerobacterales	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SX3_k127_2247017_1	1047013.AQSP01000071_gene1939	6.051e-53	190.0	COG1297@1|root,COG1297@2|Bacteria,2NP0C@2323|unclassified Bacteria	2|Bacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SX3_k127_2250541_0	1191523.MROS_1593	6.508e-219	707.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	ko:K06889,ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,Peptidase_S9
SX3_k127_2250541_1	404589.Anae109_1823	3.354e-06	55.0	COG0484@1|root,COG0484@2|Bacteria,1QYGD@1224|Proteobacteria,43CCI@68525|delta/epsilon subdivisions,2X7NG@28221|Deltaproteobacteria,2Z1CZ@29|Myxococcales	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	GSu_C4xC__C2xCH
SX3_k127_2253997_1	459349.CLOAM1235	3.406e-10	67.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
SX3_k127_2253997_0	861450.HMPREF0080_01562	3.069e-100	342.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4H20Q@909932|Negativicutes	909932|Negativicutes	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SX3_k127_2254700_3	240016.ABIZ01000001_gene4450	9.161e-06	49.0	COG0673@1|root,COG0673@2|Bacteria,46SAE@74201|Verrucomicrobia,2IU1W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SX3_k127_2254700_1	269799.Gmet_2353	1.307e-73	270.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2WJVP@28221|Deltaproteobacteria,43RXH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
SX3_k127_2254700_0	1379698.RBG1_1C00001G1649	1.891e-130	432.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,2NNYX@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171	3.5.1.108,4.2.1.59	ko:K02372,ko:K02535,ko:K13599,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020	M00060,M00083,M00498,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022	-	-	-	FabA,LpxC
SX3_k127_2254700_2	1379698.RBG1_1C00001G1848	3.137e-23	101.0	COG1044@1|root,COG1044@2|Bacteria,2NNSF@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	ic_1306.c0216	Hexapep,Hexapep_2,LpxD
SX3_k127_2261747_2	945713.IALB_2117	3.496e-11	75.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C10,Phage-tail_3,Prophage_tail,SLH
SX3_k127_2261747_1	797209.ZOD2009_05987	1.616e-14	86.0	COG3291@1|root,arCOG02540@1|root,arCOG04500@1|root,arCOG10954@1|root,arCOG02508@2157|Archaea,arCOG02540@2157|Archaea,arCOG04500@2157|Archaea,arCOG10954@2157|Archaea,2XWGB@28890|Euryarchaeota,23UX2@183963|Halobacteria	183963|Halobacteria	M	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2261747_0	459349.CLOAM0582	3.767e-20	104.0	COG1572@1|root,COG3391@1|root,COG4412@1|root,COG4733@1|root,COG1572@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria,COG4733@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	3.4.21.96	ko:K01361,ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	F5_F8_type_C,Glucosaminidase,SLH
SX3_k127_2265318_0	498761.HM1_2051	7.526e-57	204.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SX3_k127_2265318_1	326427.Cagg_2846	1.067e-23	111.0	COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi,375BR@32061|Chloroflexia	32061|Chloroflexia	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SX3_k127_2268638_0	706587.Desti_1495	6.389e-117	393.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SX3_k127_2268638_1	1232410.KI421424_gene1590	5.602e-44	179.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43C4K@68525|delta/epsilon subdivisions,2X7F1@28221|Deltaproteobacteria,43TX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains HisKA, HATPase_c	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SX3_k127_2268638_2	1121378.KB899698_gene1761	1.196e-18	98.0	COG0737@1|root,COG0737@2|Bacteria,1WI46@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
SX3_k127_2274483_0	720554.Clocl_2944	1.552e-07	59.0	COG1404@1|root,COG2304@1|root,COG3055@1|root,COG5492@1|root,COG1404@2|Bacteria,COG2304@2|Bacteria,COG3055@2|Bacteria,COG5492@2|Bacteria,1V72Z@1239|Firmicutes,24MBX@186801|Clostridia	186801|Clostridia	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,SLH
SX3_k127_2278954_0	204669.Acid345_0209	1.59e-31	132.0	COG4219@1|root,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria,2JKFK@204432|Acidobacteriia	204432|Acidobacteriia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
SX3_k127_2278954_1	1047013.AQSP01000134_gene1374	3.23e-12	76.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K16919	ko02010,map02010	M00254,M00584	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,ABC_transp_aux
SX3_k127_2289404_1	290397.Adeh_1548	2.315e-31	135.0	COG3115@1|root,COG3115@2|Bacteria,1QW35@1224|Proteobacteria,42UFZ@68525|delta/epsilon subdivisions,2WR5D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2289404_0	309807.SRU_1922	6.303e-54	198.0	COG4089@1|root,COG4089@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1614)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1614
SX3_k127_2289404_2	591019.Shell_0384	7.664e-17	89.0	COG2110@1|root,arCOG04225@2157|Archaea,2XQEQ@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SX3_k127_2293659_0	269799.Gmet_2563	4.111e-88	306.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43U5W@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	gnfM	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SX3_k127_229949_1	194439.CT2036	1.936e-21	100.0	COG0204@1|root,COG0204@2|Bacteria,1FDPA@1090|Chlorobi	1090|Chlorobi	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SX3_k127_229949_0	1157490.EL26_18165	3.596e-46	175.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,277VY@186823|Alicyclobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SX3_k127_2307652_0	1047013.AQSP01000140_gene2549	9.548e-114	377.0	COG1067@1|root,COG1067@2|Bacteria,2NP29@2323|unclassified Bacteria	2|Bacteria	O	peptidase S16	ycbZ	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
SX3_k127_2311246_0	635013.TherJR_2980	6.01e-46	175.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,260HS@186807|Peptococcaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SX3_k127_2311246_1	391623.TERMP_00600	4.335e-18	89.0	COG1371@1|root,arCOG04055@2157|Archaea,2XXRX@28890|Euryarchaeota,242RW@183968|Thermococci	183968|Thermococci	J	Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently	-	GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360	-	-	-	-	-	-	-	-	-	-	Archease
SX3_k127_2329946_1	290397.Adeh_2722	1.637e-20	104.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
SX3_k127_2329946_0	1379698.RBG1_1C00001G1162	8.524e-39	157.0	COG0726@1|root,COG0726@2|Bacteria,2NPY1@2323|unclassified Bacteria	2|Bacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Polysacc_deac_1
SX3_k127_2329946_2	717605.Theco_2048	1.002e-18	86.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,4HIZ3@91061|Bacilli,26WU8@186822|Paenibacillaceae	91061|Bacilli	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SX3_k127_2343357_2	1379698.RBG1_1C00001G0050	1.697e-29	118.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2,Pyr_redox_3
SX3_k127_2343357_1	429009.Adeg_2015	2.563e-63	220.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,42GG4@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD,NADH_4Fe-4S
SX3_k127_2343357_0	1379698.RBG1_1C00001G0048	4.648e-108	358.0	COG1941@1|root,COG1941@2|Bacteria,2NQP6@2323|unclassified Bacteria	2|Bacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_lg_C,Fer4,FlpD,Oxidored_q6
SX3_k127_2343357_3	429009.Adeg_2013	3.385e-26	108.0	COG3259@1|root,COG3259@2|Bacteria,1UZNV@1239|Firmicutes,24F0H@186801|Clostridia,42HYI@68295|Thermoanaerobacterales	186801|Clostridia	C	Nickel-dependent hydrogenase	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
SX3_k127_2355515_0	309807.SRU_0621	6.418e-32	137.0	COG0472@1|root,COG1086@1|root,COG0472@2|Bacteria,COG1086@2|Bacteria,4NGKM@976|Bacteroidetes,1FJW4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
SX3_k127_2358263_0	269800.Tfu_0785	8.781e-27	128.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4EHPV@85012|Streptosporangiales	201174|Actinobacteria	S	Insulinase (Peptidase family M16)	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SX3_k127_2364653_0	533240.CRC_01020	7.815e-114	377.0	COG1404@1|root,COG2931@1|root,COG3121@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3121@2|Bacteria,1GJ7F@1117|Cyanobacteria,1HQZ9@1161|Nostocales	1117|Cyanobacteria	QU	Domains in Na-Ca exchangers and integrin-beta4	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
SX3_k127_2369619_0	665571.STHERM_c01570	2.467e-137	448.0	COG0173@1|root,COG0173@2|Bacteria,2J5KG@203691|Spirochaetes	203691|Spirochaetes	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SX3_k127_2369776_1	592015.HMPREF1705_01565	5.18e-41	156.0	COG0222@1|root,COG0222@2|Bacteria,3TB80@508458|Synergistetes	508458|Synergistetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SX3_k127_2369776_0	1379698.RBG1_1C00001G1605	9.766e-234	737.0	COG0085@1|root,COG0085@2|Bacteria,2NNM9@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SX3_k127_2376814_1	1033802.SSPSH_003236	1.278e-05	53.0	COG0500@1|root,COG2226@2|Bacteria,1PN45@1224|Proteobacteria,1RP4K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	methyltransferase	yafE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SX3_k127_2376814_0	945713.IALB_3164	1.653e-119	400.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SX3_k127_2379310_1	1379698.RBG1_1C00001G1788	2.317e-24	110.0	COG2067@1|root,COG3292@1|root,COG2067@2|Bacteria,COG3292@2|Bacteria,2NPQZ@2323|unclassified Bacteria	2|Bacteria	I	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Reg_prop,Reprolysin_5,VCBS
SX3_k127_2379310_0	1379698.RBG1_1C00001G1787	5.416e-39	166.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria,2NPRE@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	DUF1863,PQQ_2
SX3_k127_2381321_0	1209989.TepiRe1_0359	9.058e-68	243.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,42FDQ@68295|Thermoanaerobacterales	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
SX3_k127_2381321_1	580332.Slit_1062	3.486e-41	157.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria,44V46@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SX3_k127_2383093_0	521045.Kole_0614	1.667e-106	362.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	ko:K06889,ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,Malectin,Peptidase_S9
SX3_k127_238345_0	383372.Rcas_0946	8.175e-89	305.0	COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi,374V0@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SX3_k127_238345_1	945713.IALB_2930	3.685e-45	178.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_238345_2	517417.Cpar_1584	1.08e-34	141.0	COG2204@1|root,COG2204@2|Bacteria,1FDRE@1090|Chlorobi	1090|Chlorobi	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
SX3_k127_239282_1	1321779.HMPREF1984_01922	1.278e-13	72.0	COG0571@1|root,COG0571@2|Bacteria,378UZ@32066|Fusobacteria	32066|Fusobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SX3_k127_239282_0	1191523.MROS_2052	1.772e-17	96.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
SX3_k127_239364_1	469383.Cwoe_4933	8.349e-34	136.0	COG3320@1|root,COG3320@2|Bacteria,2I9YC@201174|Actinobacteria	201174|Actinobacteria	Q	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
SX3_k127_239364_0	42256.RradSPS_1842	1.541e-101	345.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CPFF@84995|Rubrobacteria	84995|Rubrobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SX3_k127_2396347_0	1411123.JQNH01000001_gene2815	6.696e-145	473.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TRP2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SX3_k127_2396347_1	396588.Tgr7_2385	2.867e-23	102.0	COG0236@1|root,COG0236@2|Bacteria,1NC80@1224|Proteobacteria,1SJ0G@1236|Gammaproteobacteria,1X1K5@135613|Chromatiales	135613|Chromatiales	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
SX3_k127_2403007_0	1449126.JQKL01000012_gene3514	2.43e-127	423.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,267ZX@186813|unclassified Clostridiales	186801|Clostridia	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SX3_k127_2403007_2	644966.Tmar_0853	2.017e-98	333.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3WCFH@538999|Clostridiales incertae sedis	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SX3_k127_2403007_1	1379698.RBG1_1C00001G0838	1.123e-126	415.0	COG2255@1|root,COG2255@2|Bacteria,2NNUG@2323|unclassified Bacteria	2|Bacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SX3_k127_2407476_0	1519464.HY22_06950	1.208e-33	147.0	COG1293@1|root,COG1293@2|Bacteria,1FDH7@1090|Chlorobi	1090|Chlorobi	K	Fibronectin-binding protein A N-terminus (FbpA)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
SX3_k127_2407476_1	1307759.JOMJ01000004_gene2936	4.363e-13	70.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,42M3V@68525|delta/epsilon subdivisions,2WJJ4@28221|Deltaproteobacteria,2M8I8@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SX3_k127_2411837_0	1379270.AUXF01000006_gene109	4.561e-82	293.0	COG0539@1|root,COG2183@1|root,COG0539@2|Bacteria,COG2183@2|Bacteria,1ZSKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SX3_k127_2411837_1	1121472.AQWN01000003_gene1637	2.192e-72	256.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,26081@186807|Peptococcaceae	186801|Clostridia	IJM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
SX3_k127_2415792_1	1437610.BREU_1028	2.488e-42	159.0	COG0425@1|root,COG0607@1|root,COG2210@1|root,COG0425@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,2I65D@201174|Actinobacteria,4D0GG@85004|Bifidobacteriales	201174|Actinobacteria	OP	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Rhodanese,TusA
SX3_k127_2415792_0	760568.Desku_1388	1.036e-83	286.0	COG1032@1|root,COG1032@2|Bacteria,1TQF0@1239|Firmicutes,24A0T@186801|Clostridia,2611F@186807|Peptococcaceae	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SX3_k127_2428246_1	357808.RoseRS_2711	1.103e-60	214.0	COG0569@1|root,COG2985@1|root,COG0569@2|Bacteria,COG2985@2|Bacteria,2G64U@200795|Chloroflexi,374ZG@32061|Chloroflexia	32061|Chloroflexia	P	YidE YbjL duplication domain protein	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
SX3_k127_2428246_0	926569.ANT_16670	6.654e-126	413.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi	200795|Chloroflexi	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SX3_k127_2428246_2	926569.ANT_16660	5.109e-28	117.0	COG0446@1|root,COG1034@1|root,COG1143@1|root,COG1251@1|root,COG0446@2|Bacteria,COG1034@2|Bacteria,COG1143@2|Bacteria,COG1251@2|Bacteria,2G6SN@200795|Chloroflexi	200795|Chloroflexi	C	BFD domain protein 2Fe-2S -binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD,Pyr_redox_2
SX3_k127_2428259_1	926569.ANT_16670	1.488e-41	157.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi	200795|Chloroflexi	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SX3_k127_2428259_0	269799.Gmet_2550	6.989e-60	212.0	COG0569@1|root,COG2985@1|root,COG0569@2|Bacteria,COG2985@2|Bacteria,1MUVM@1224|Proteobacteria,42P36@68525|delta/epsilon subdivisions,2WKGD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM YidE YbjL duplication	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
SX3_k127_2432091_1	1134413.ANNK01000162_gene3529	2.371e-89	303.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus	91061|Bacilli	C	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively	gabD_2	-	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SX3_k127_2432091_0	1340434.AXVA01000006_gene4322	1.454e-111	374.0	COG0460@1|root,COG0460@2|Bacteria,1URXW@1239|Firmicutes,4HBHY@91061|Bacilli,1ZC5K@1386|Bacillus	91061|Bacilli	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ELFV_dehydrog,Homoserine_dh,NAD_binding_3
SX3_k127_2432091_2	1121929.KB898666_gene2422	3.542e-31	125.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HBQK@91061|Bacilli	91061|Bacilli	E	Methionine gamma-lyase	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SX3_k127_2434829_0	1499967.BAYZ01000103_gene3728	1.829e-35	147.0	COG2350@1|root,COG2350@2|Bacteria,2NR74@2323|unclassified Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
SX3_k127_2437979_2	1408433.JHXV01000027_gene3728	4.26e-08	57.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
SX3_k127_2437979_0	1009370.ALO_07458	1.889e-95	332.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,4H301@909932|Negativicutes	909932|Negativicutes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SX3_k127_2437979_1	218284.CCDN010000008_gene4081	2.826e-74	266.0	COG1215@1|root,COG1215@2|Bacteria,1TPY9@1239|Firmicutes,4HF9W@91061|Bacilli,1ZGWH@1386|Bacillus	91061|Bacilli	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SX3_k127_2453477_0	945713.IALB_0649	3.177e-166	533.0	COG1674@1|root,COG1674@2|Bacteria	2|Bacteria	D	ftsk spoiiie	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SX3_k127_2458369_1	909663.KI867151_gene3024	1.158e-09	67.0	COG1215@1|root,COG1215@2|Bacteria,1RIJ7@1224|Proteobacteria,43CX5@68525|delta/epsilon subdivisions,2X853@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SX3_k127_2458369_0	1121440.AUMA01000001_gene30	8.773e-28	125.0	COG0438@1|root,COG0438@2|Bacteria,1QUN0@1224|Proteobacteria,43BMP@68525|delta/epsilon subdivisions,2WV0M@28221|Deltaproteobacteria,2M92W@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2458369_2	1117943.SFHH103_01661	6.923e-09	60.0	COG4653@1|root,COG4653@2|Bacteria,1MYMH@1224|Proteobacteria,2TUSK@28211|Alphaproteobacteria,4BDCP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Major capsid protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
SX3_k127_2468343_0	1343739.PAP_01240	1.225e-25	116.0	COG0778@1|root,arCOG00288@2157|Archaea,2XXW2@28890|Euryarchaeota,242IJ@183968|Thermococci	183968|Thermococci	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SX3_k127_2468343_1	945713.IALB_2396	1.076e-16	84.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Sortilin-Vps10
SX3_k127_2472735_0	177437.HRM2_09160	2.557e-148	483.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2WJ5J@28221|Deltaproteobacteria,2MHQP@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
SX3_k127_2472735_1	1211114.ALIP01000099_gene1888	2.423e-23	109.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria,1X3WH@135614|Xanthomonadales	135614|Xanthomonadales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SX3_k127_2480403_0	240292.Ava_1611	7.779e-244	776.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
SX3_k127_2480403_1	1170562.Cal6303_2603	5.057e-142	464.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Condensation,PP-binding
SX3_k127_2482997_1	555088.DealDRAFT_1022	2.829e-24	108.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,42K0F@68298|Syntrophomonadaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SX3_k127_2482997_2	246194.CHY_0344	1.455e-06	56.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24RP5@186801|Clostridia,42HFE@68295|Thermoanaerobacterales	186801|Clostridia	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
SX3_k127_2482997_0	880073.Calab_1721	3.63e-88	310.0	COG0768@1|root,COG0768@2|Bacteria,2NNYI@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding protein 2	mrdA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604	PBP_dimer,Transpeptidase
SX3_k127_2502839_1	717605.Theco_0596	5.704e-42	159.0	COG5587@1|root,COG5587@2|Bacteria,1UDMR@1239|Firmicutes	1239|Firmicutes	S	TIGR02453 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SX3_k127_2502839_0	1123073.KB899245_gene76	3.811e-50	201.0	COG0823@1|root,COG0823@2|Bacteria,1MZ1T@1224|Proteobacteria,1RMNE@1236|Gammaproteobacteria,1X7UX@135614|Xanthomonadales	135614|Xanthomonadales	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SX3_k127_2502839_2	61273.S3CSD4	5.721e-35	153.0	COG0666@1|root,KOG0504@2759|Eukaryota,39YNX@33154|Opisthokonta,3Q4K4@4751|Fungi,3RMU5@4890|Ascomycota,21RFD@147550|Sordariomycetes,3UW62@5151|Ophiostomatales	4751|Fungi	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4,NACHT,NACHT_N
SX3_k127_2502855_1	909943.HIMB100_00019480	1.927e-97	325.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,4BP98@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	rkpK	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SX3_k127_2502855_2	641112.ACOK01000089_gene1282	6.28e-71	254.0	COG1089@1|root,COG1089@2|Bacteria,1UJFF@1239|Firmicutes,24818@186801|Clostridia,3WGYD@541000|Ruminococcaceae	186801|Clostridia	M	RmlD substrate binding domain	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SX3_k127_2502855_0	1047013.AQSP01000138_gene1042	5.328e-133	432.0	COG1089@1|root,COG1089@2|Bacteria,2NP6U@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	wcbK	-	1.1.1.281,4.2.1.47	ko:K01711,ko:K15856	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888,R03397,R03399	RC00182,RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SX3_k127_2502855_3	1408322.JHYK01000007_gene2094	1.612e-45	171.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,2494X@186801|Clostridia,27KNS@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
SX3_k127_2503716_1	1123242.JH636434_gene5411	2.234e-66	240.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2IYZ1@203682|Planctomycetes	203682|Planctomycetes	A	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SX3_k127_2503716_0	313628.LNTAR_05456	1.044e-72	258.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
SX3_k127_2503716_2	247490.KSU1_C0859	1.486e-31	134.0	28MJ6@1|root,2ZAVS@2|Bacteria,2J0MI@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2520003_0	1124780.ANNU01000016_gene1821	6.525e-66	239.0	COG0729@1|root,COG0729@2|Bacteria,4NMUN@976|Bacteroidetes,47Y2C@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
SX3_k127_2533883_0	1125863.JAFN01000001_gene301	6.702e-100	338.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	PFAM SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SX3_k127_2533883_1	1459636.NTE_02921	3.005e-51	188.0	COG0299@1|root,arCOG02825@2157|Archaea,41SH3@651137|Thaumarchaeota	651137|Thaumarchaeota	F	phosphoribosylglycinamide formyltransferase	-	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SX3_k127_2535150_0	880073.Calab_3524	1.398e-66	239.0	2CF1V@1|root,2Z8M1@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4876)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4876
SX3_k127_2541803_0	1121957.ATVL01000014_gene1459	4.227e-61	228.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2556210_0	266748.HY04_00770	1.799e-31	134.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1HX7X@117743|Flavobacteriia,3ZPKE@59732|Chryseobacterium	976|Bacteroidetes	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SX3_k127_2556210_1	485913.Krac_7605	9.938e-10	63.0	2DUX0@1|root,33ST3@2|Bacteria	2|Bacteria	S	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SX3_k127_2556970_2	338966.Ppro_1929	3.101e-55	196.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2WIPG@28221|Deltaproteobacteria,43TAG@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	Nitro_FeMo-Co,ParA
SX3_k127_2556970_0	880073.Calab_2517	1.897e-166	532.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SX3_k127_2556970_3	557598.LHK_01934	1.203e-50	189.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2VIBH@28216|Betaproteobacteria,2KQET@206351|Neisseriales	206351|Neisseriales	U	UPF0056 membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
SX3_k127_2556970_1	313606.M23134_05227	1.417e-133	463.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,4PM4C@976|Bacteroidetes,47KZM@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,fn3
SX3_k127_2556970_4	247490.KSU1_C0730	5.745e-06	60.0	COG2234@1|root,COG3291@1|root,COG3420@1|root,COG4409@1|root,COG5184@1|root,COG5276@1|root,COG2234@2|Bacteria,COG3291@2|Bacteria,COG3420@2|Bacteria,COG4409@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	iap	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6	ko:K01179,ko:K03929,ko:K09612,ko:K12287,ko:K19701,ko:K19702	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko02044	-	CE10,GH5,GH9	-	Beta_helix,Peptidase_M28
SX3_k127_2559723_3	762903.Pedsa_1501	3.393e-10	66.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1IQ3N@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SX3_k127_2559723_2	1379698.RBG1_1C00001G0332	6.571e-12	74.0	COG2980@1|root,COG2980@2|Bacteria,2NQ1I@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	lptE	GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788	LptE
SX3_k127_2559723_0	1121918.ARWE01000001_gene445	3.629e-138	455.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SX3_k127_2559723_1	269799.Gmet_2562	5.902e-58	218.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,43T97@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Nitrogen fixation master sensor histidine kinase, PAS domain-containing	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
SX3_k127_2581271_0	439497.RR11_881	5.472e-09	61.0	COG3311@1|root,COG3311@2|Bacteria,1N72I@1224|Proteobacteria,2UM3F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SX3_k127_2587125_1	331678.Cphamn1_0837	7.704e-67	244.0	COG0249@1|root,COG0249@2|Bacteria,1FD9B@1090|Chlorobi	1090|Chlorobi	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SX3_k127_2587125_2	1260251.SPISAL_06435	1.439e-05	57.0	COG3147@1|root,COG3147@2|Bacteria,1MXHQ@1224|Proteobacteria,1RRKM@1236|Gammaproteobacteria,1WZKK@135613|Chromatiales	135613|Chromatiales	D	Sporulation related domain	-	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
SX3_k127_2587125_3	765911.Thivi_3296	0.0001378	53.0	COG0457@1|root,COG0457@2|Bacteria	765911.Thivi_3296|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2587125_0	643648.Slip_1071	9.471e-93	323.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,42JIZ@68298|Syntrophomonadaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SX3_k127_2589809_0	1499967.BAYZ01000003_gene5878	1.811e-211	670.0	COG0441@1|root,COG0441@2|Bacteria,2NNMT@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SX3_k127_2602170_0	1173028.ANKO01000116_gene5736	1.014e-50	186.0	COG0451@1|root,COG0451@2|Bacteria,1GC04@1117|Cyanobacteria	1117|Cyanobacteria	M	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
SX3_k127_2602170_1	535289.Dtpsy_0560	5.052e-31	134.0	COG0451@1|root,COG0451@2|Bacteria,1MVPZ@1224|Proteobacteria,2VM2A@28216|Betaproteobacteria,4AA2Z@80864|Comamonadaceae	28216|Betaproteobacteria	M	Nad-dependent epimerase dehydratase	-	-	1.1.1.135,1.1.1.281	ko:K15856,ko:K22252	ko00051,ko00520,map00051,map00520	-	R03396,R03397,R03398,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SX3_k127_2605664_1	1121930.AQXG01000002_gene2074	2.827e-15	76.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IQ09@117747|Sphingobacteriia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SX3_k127_2605664_0	880073.Calab_1134	1.657e-124	417.0	COG2091@1|root,COG2091@2|Bacteria,2NQGR@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SX3_k127_2623476_0	404589.Anae109_1549	2.085e-107	376.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,1MV1P@1224|Proteobacteria,42PPB@68525|delta/epsilon subdivisions,2X5YN@28221|Deltaproteobacteria,2YUEJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12
SX3_k127_2623476_1	1379698.RBG1_1C00001G1616	3.042e-70	242.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
SX3_k127_2623505_0	1210884.HG799462_gene8903	3.243e-11	75.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IYTQ@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16
SX3_k127_2624732_0	518766.Rmar_0638	5.002e-203	637.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1FIMH@1100069|Bacteroidetes Order II. Incertae sedis	2|Bacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SX3_k127_2624732_1	518766.Rmar_0637	3.86e-28	115.0	2FDJV@1|root,345M5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2624878_2	1122918.KB907258_gene2591	5.991e-18	84.0	COG2204@1|root,COG2204@2|Bacteria,1UHXE@1239|Firmicutes,4ISDB@91061|Bacilli,26XDQ@186822|Paenibacillaceae	91061|Bacilli	T	Chemotaxis protein CheY	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SX3_k127_2624878_0	401526.TcarDRAFT_2113	5.262e-33	140.0	COG1776@1|root,COG1776@2|Bacteria,1UNKB@1239|Firmicutes,4H25I@909932|Negativicutes	909932|Negativicutes	NT	Chemotaxis protein CheC	cheC	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
SX3_k127_2624878_1	477974.Daud_1792	3.776e-18	89.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia,2603B@186807|Peptococcaceae	186801|Clostridia	NT	Signal transducing histidine kinase homodimeric	cheA3	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
SX3_k127_2632001_0	179408.Osc7112_2619	5.55e-66	258.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H8D7@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
SX3_k127_2632001_1	1484460.JSWG01000015_gene1175	8.52e-19	94.0	COG1595@1|root,COG1595@2|Bacteria,4NNP4@976|Bacteroidetes,1I284@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SX3_k127_2634292_2	1047013.AQSP01000098_gene2564	3.598e-12	76.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4241,HEAT,HEAT_2
SX3_k127_2634292_0	1047013.AQSP01000098_gene2562	5.453e-31	129.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SX3_k127_2634292_1	383372.Rcas_0080	7.593e-24	117.0	COG1287@1|root,COG1287@2|Bacteria,2G9P1@200795|Chloroflexi,375X4@32061|Chloroflexia	32061|Chloroflexia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SX3_k127_2634292_3	1454004.AW11_02184	9.839e-06	52.0	2BDT3@1|root,327GV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2636391_1	401526.TcarDRAFT_1987	3.22e-10	71.0	COG0419@1|root,COG0419@2|Bacteria,1UI2P@1239|Firmicutes,4H37A@909932|Negativicutes	909932|Negativicutes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
SX3_k127_2636391_0	401526.TcarDRAFT_1986	1.307e-21	106.0	COG0420@1|root,COG0420@2|Bacteria	2|Bacteria	L	3'-5' exonuclease activity	yhaO	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
SX3_k127_2658191_3	1408422.JHYF01000006_gene1211	4.516e-05	48.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,36HRK@31979|Clostridiaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SX3_k127_2658191_0	335543.Sfum_0705	5.564e-75	262.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SX3_k127_2658191_1	1047013.AQSP01000051_gene2576	2.307e-55	217.0	COG2220@1|root,COG2220@2|Bacteria,2NRBH@2323|unclassified Bacteria	2|Bacteria	S	Beta-lactamase superfamily domain	folD4	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SX3_k127_2658191_2	7668.SPU_001249-tr	1.366e-54	215.0	COG0666@1|root,KOG0504@2759|Eukaryota,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3BGGV@33208|Metazoa,3CT1S@33213|Bilateria	33208|Metazoa	M	ankyrin 3, node of Ranvier (ankyrin G)	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,ZU5
SX3_k127_2666304_0	1379698.RBG1_1C00001G1319	7.8e-67	239.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SX3_k127_2666304_1	59374.Fisuc_0695	7.222e-50	194.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SX3_k127_2666304_2	309801.trd_1481	6.481e-41	164.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi,27Y5S@189775|Thermomicrobia	189775|Thermomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SX3_k127_2666304_3	1219084.AP014508_gene952	1.342e-20	93.0	COG0781@1|root,COG0781@2|Bacteria,2GDBQ@200918|Thermotogae	200918|Thermotogae	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SX3_k127_2689981_0	446462.Amir_2703	4.759e-29	132.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2694235_0	1047013.AQSP01000108_gene2065	1.558e-122	406.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SX3_k127_2696509_0	1408473.JHXO01000001_gene2146	4.274e-81	286.0	COG1453@1|root,COG1453@2|Bacteria,4NJU2@976|Bacteroidetes,2G2UD@200643|Bacteroidia	976|Bacteroidetes	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
SX3_k127_2696509_1	234267.Acid_5772	6.4e-28	115.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SX3_k127_2709684_0	1501230.ET33_13240	5.003e-56	201.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.7.1.83	ko:K16328	ko00240,map00240	-	R03315	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SX3_k127_2709684_1	653733.Selin_0904	2.813e-39	150.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	macB_2	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
SX3_k127_2712188_0	941449.dsx2_1511	0.0001697	46.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2WITA@28221|Deltaproteobacteria,2M93Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
SX3_k127_2728496_0	555079.Toce_0099	2.937e-35	148.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,42EQJ@68295|Thermoanaerobacterales	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SX3_k127_2728496_1	1379270.AUXF01000001_gene2297	2.046e-06	59.0	COG1572@1|root,COG2304@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,1ZUB7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
SX3_k127_2738247_1	1185876.BN8_03232	5.193e-22	110.0	28N6F@1|root,2ZBBB@2|Bacteria,4NGM1@976|Bacteroidetes,47P0U@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2738247_0	1499967.BAYZ01000159_gene484	4.469e-105	351.0	COG0598@1|root,COG0598@2|Bacteria,2NPAW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SX3_k127_2748472_1	1179777.D500_0511	1.901e-12	76.0	COG0357@1|root,COG0357@2|Bacteria,3WTR7@544448|Tenericutes	544448|Tenericutes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	gidB	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SX3_k127_2748472_0	518766.Rmar_2757	2.485e-186	601.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,1FIT2@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
SX3_k127_2761466_3	1047013.AQSP01000133_gene2118	2.489e-13	71.0	COG1321@1|root,COG1321@2|Bacteria,2NRHI@2323|unclassified Bacteria	2|Bacteria	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SX3_k127_2761466_0	1047013.AQSP01000133_gene2120	1.026e-272	851.0	COG0370@1|root,COG0370@2|Bacteria,2NNZ4@2323|unclassified Bacteria	2|Bacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
SX3_k127_2761466_1	1118054.CAGW01000007_gene3842	6.985e-51	194.0	COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,4HB9F@91061|Bacilli	91061|Bacilli	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SX3_k127_277473_0	240015.ACP_2455	6.032e-113	368.0	COG0499@1|root,COG0499@2|Bacteria,3Y2J2@57723|Acidobacteria,2JIFV@204432|Acidobacteriia	204432|Acidobacteriia	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SX3_k127_277473_1	518766.Rmar_2301	4.196e-10	72.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_2301|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2777645_1	867903.ThesuDRAFT_00342	7.524e-56	205.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,3WCKI@538999|Clostridiales incertae sedis	186801|Clostridia	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
SX3_k127_2777645_2	867903.ThesuDRAFT_00340	2.522e-54	201.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,3WD60@538999|Clostridiales incertae sedis	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SX3_k127_2777645_3	693746.OBV_23260	3.851e-05	51.0	COG1758@1|root,COG1758@2|Bacteria,1VII0@1239|Firmicutes,24SVW@186801|Clostridia,2N7S4@216572|Oscillospiraceae	186801|Clostridia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SX3_k127_2777645_0	1121015.N789_08500	2.928e-100	340.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1X3EH@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	dfp	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SX3_k127_2792172_0	56780.SYN_00152	7.165e-198	623.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MR61@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, NADH-binding	-	-	1.12.1.3,1.6.5.3	ko:K00124,ko:K00335,ko:K18331	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
SX3_k127_2793949_0	1379698.RBG1_1C00001G1481	2.241e-71	257.0	COG0358@1|root,COG0358@2|Bacteria,2NNNJ@2323|unclassified Bacteria	2|Bacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
SX3_k127_2799715_0	1379270.AUXF01000005_gene395	3.176e-11	73.0	COG0484@1|root,COG0484@2|Bacteria,1ZT5T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SX3_k127_2803496_0	1121904.ARBP01000002_gene7127	2.099e-41	166.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SX3_k127_2812065_0	925409.KI911562_gene2032	3.698e-208	666.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1IPND@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
SX3_k127_2812065_1	1123242.JH636434_gene4856	4.276e-198	630.0	COG0591@1|root,COG0591@2|Bacteria,2J2KC@203682|Planctomycetes	203682|Planctomycetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SX3_k127_2827568_0	234267.Acid_1536	4.097e-131	429.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3IB@57723|Acidobacteria	57723|Acidobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SX3_k127_2827568_1	401053.AciPR4_2106	0.0002943	51.0	COG3386@1|root,COG4934@1|root,COG3386@2|Bacteria,COG4934@2|Bacteria,3Y43Q@57723|Acidobacteria,2JP03@204432|Acidobacteriia	204432|Acidobacteriia	G	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,NHL
SX3_k127_2829897_0	1123368.AUIS01000014_gene2292	4.518e-129	442.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SX3_k127_2829897_1	46234.ANA_C11025	1.537e-15	80.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HJM4@1161|Nostocales	1117|Cyanobacteria	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
SX3_k127_2835841_1	404380.Gbem_1112	5.481e-06	59.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SX3_k127_2835841_0	765911.Thivi_2190	9.823e-11	75.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1WW19@135613|Chromatiales	135613|Chromatiales	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SX3_k127_2838513_1	862751.SACTE_1542	1.914e-16	89.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SX3_k127_2838513_0	315730.BcerKBAB4_3683	7.119e-57	207.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,1ZCUF@1386|Bacillus	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SX3_k127_2846962_0	479434.Sthe_2092	1.157e-53	203.0	COG1074@1|root,COG1074@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	-	-	3.1.11.5,3.1.12.1,3.6.4.12	ko:K01144,ko:K07464,ko:K16898	-	-	-	-	ko00000,ko01000,ko02048,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SX3_k127_2847811_2	440512.C211_08439	1.029e-05	52.0	2E9J1@1|root,333RY@2|Bacteria,1NIX0@1224|Proteobacteria,1SGM0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2847811_0	243231.GSU2614	1.05e-109	377.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2WJE3@28221|Deltaproteobacteria,43UIB@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SX3_k127_2847811_1	1173026.Glo7428_0017	1.522e-08	67.0	COG1490@1|root,COG1490@2|Bacteria,1G5CN@1117|Cyanobacteria	1117|Cyanobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SX3_k127_2853772_2	635013.TherJR_0937	6.045e-05	46.0	COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia,2673V@186807|Peptococcaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Fer4,Fer4_7,Pyr_redox_2
SX3_k127_2853772_0	374847.Kcr_1114	9.649e-55	209.0	COG0247@1|root,COG2048@1|root,arCOG00964@2157|Archaea,arCOG05014@2157|Archaea	2157|Archaea	C	Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrE may be responsible for anchoring the complex to the membrane	hdrE	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0031224,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0044425,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576	1.8.98.1	ko:K08265,ko:K16887	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	-	R04540	RC00011	ko00000,ko00001,ko01000	-	-	-	Fer4_17,Nitrate_red_gam
SX3_k127_2864251_1	94624.Bpet1043	2.493e-05	53.0	28IH0@1|root,2Z8IB@2|Bacteria,1R6A9@1224|Proteobacteria,2VNIF@28216|Betaproteobacteria,3T54Y@506|Alcaligenaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2864251_0	1454004.AW11_02382	3.302e-06	53.0	COG1074@1|root,COG1074@2|Bacteria,1QUUZ@1224|Proteobacteria,2WI1S@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PDDEXK-like domain of unknown function (DUF3799)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3799
SX3_k127_2867788_1	314345.SPV1_05347	1.196e-30	126.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SX3_k127_2867788_0	768706.Desor_3341	5.871e-49	184.0	COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,2497A@186801|Clostridia,261GZ@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
SX3_k127_2867788_2	693661.Arcve_1751	1.998e-11	71.0	COG2029@1|root,arCOG04875@2157|Archaea,2XV8B@28890|Euryarchaeota	28890|Euryarchaeota	S	Domain of unknown function (DUF366)	-	-	-	ko:K09139	-	-	-	-	ko00000	-	-	-	DUF366
SX3_k127_2872383_0	1382306.JNIM01000001_gene2893	1.625e-33	131.0	COG4948@1|root,COG4948@2|Bacteria,2G8E6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Mandelate racemase muconate lactonizing protein	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SX3_k127_2872383_1	479434.Sthe_2092	9.581e-20	98.0	COG1074@1|root,COG1074@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	-	-	3.1.11.5,3.1.12.1,3.6.4.12	ko:K01144,ko:K07464,ko:K16898	-	-	-	-	ko00000,ko01000,ko02048,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SX3_k127_287314_0	502025.Hoch_2091	6.653e-24	108.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_287314_1	880073.Calab_1394	1.401e-07	64.0	COG2067@1|root,COG2067@2|Bacteria,2NPQZ@2323|unclassified Bacteria	2|Bacteria	I	Two component regulator propeller	porV	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2881417_2	862965.PARA_13210	1.857e-05	47.0	2ATIV@1|root,31J2V@2|Bacteria,1QI4I@1224|Proteobacteria,1TFY1@1236|Gammaproteobacteria,1YAFM@135625|Pasteurellales	135625|Pasteurellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2881417_0	338966.Ppro_2966	4.644e-79	282.0	COG1625@1|root,COG1625@2|Bacteria,1R76F@1224|Proteobacteria,42PNQ@68525|delta/epsilon subdivisions,2WKT9@28221|Deltaproteobacteria,43SDY@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
SX3_k127_2881417_1	717606.PaecuDRAFT_3293	6.363e-20	104.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,26RZ6@186822|Paenibacillaceae	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SX3_k127_2891446_0	1278073.MYSTI_00182	9.647e-06	57.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,42ZIG@68525|delta/epsilon subdivisions,2WUZE@28221|Deltaproteobacteria,2YX8Y@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SX3_k127_2908725_2	316067.Geob_2668	1.179e-16	81.0	COG1014@1|root,COG1014@2|Bacteria,1RAQ4@1224|Proteobacteria,43BEE@68525|delta/epsilon subdivisions,2WN0D@28221|Deltaproteobacteria,43TV8@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	korC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
SX3_k127_2908725_0	1121430.JMLG01000013_gene1882	5.015e-101	340.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,25CAJ@186801|Clostridia,260ZJ@186807|Peptococcaceae	186801|Clostridia	C	PFAM Thiamine pyrophosphate enzyme, C-terminal	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SX3_k127_2908725_1	1121918.ARWE01000001_gene1851	1.639e-28	117.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2WJ97@28221|Deltaproteobacteria,43S62@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
SX3_k127_2912142_0	518766.Rmar_0833	1.688e-68	242.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1FIMK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SX3_k127_2912142_1	589924.Ferp_2552	3.592e-34	136.0	COG1545@1|root,arCOG01287@2157|Archaea,2Y3J3@28890|Euryarchaeota,24718@183980|Archaeoglobi	183980|Archaeoglobi	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SX3_k127_2912142_2	1379698.RBG1_1C00001G1463	7.893e-28	116.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SX3_k127_291223_0	215803.DB30_6668	1.207e-229	748.0	COG0308@1|root,COG0308@2|Bacteria,1PTWJ@1224|Proteobacteria,438P8@68525|delta/epsilon subdivisions,2X3X0@28221|Deltaproteobacteria,2YXWZ@29|Myxococcales	28221|Deltaproteobacteria	E	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SX3_k127_291223_1	1356852.N008_05345	1.451e-104	348.0	COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,47KHD@768503|Cytophagia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SX3_k127_291629_1	1047013.AQSP01000134_gene1374	5.089e-07	58.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K16919	ko02010,map02010	M00254,M00584	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,ABC_transp_aux
SX3_k127_291629_0	1047013.AQSP01000134_gene1374	3.294e-60	225.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K16919	ko02010,map02010	M00254,M00584	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,ABC_transp_aux
SX3_k127_2927216_2	1121438.JNJA01000006_gene129	2.333e-10	67.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0023052,GO:0031224,GO:0031226,GO:0031647,GO:0031992,GO:0032991,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050821,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0065008,GO:0071944,GO:0098796,GO:0098797	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SX3_k127_2927216_0	671143.DAMO_0494	1.396e-31	134.0	COG0811@1|root,COG0811@2|Bacteria,2NPFR@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	tolQ	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
SX3_k127_2927216_1	1379698.RBG1_1C00001G1235	1.374e-10	74.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
SX3_k127_2932920_1	880073.Calab_0082	1.629e-36	145.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SX3_k127_2932920_0	96561.Dole_3235	3.614e-42	164.0	COG1234@1|root,COG1234@2|Bacteria,1PE64@1224|Proteobacteria,42RZR@68525|delta/epsilon subdivisions,2WMCC@28221|Deltaproteobacteria,2MIZZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SX3_k127_2941550_2	743718.Isova_1516	1.096e-18	92.0	COG1254@1|root,COG1254@2|Bacteria,2HZJF@201174|Actinobacteria,4F5VG@85017|Promicromonosporaceae	201174|Actinobacteria	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SX3_k127_2941550_0	452637.Oter_1726	1.579e-104	364.0	COG0265@1|root,COG0265@2|Bacteria,46UW8@74201|Verrucomicrobia,3K7DR@414999|Opitutae	2|Bacteria	M	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SX3_k127_2948210_0	502025.Hoch_1777	1.772e-41	165.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,42RA9@68525|delta/epsilon subdivisions,2WQIZ@28221|Deltaproteobacteria,2YWBB@29|Myxococcales	28221|Deltaproteobacteria	S	Phenazine biosynthesis-like protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
SX3_k127_2950284_1	96561.Dole_0811	4.528e-41	158.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria,2MJ98@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SX3_k127_2950284_0	96561.Dole_0810	1.009e-66	231.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42P7V@68525|delta/epsilon subdivisions,2WJQA@28221|Deltaproteobacteria,2MJ2Q@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
SX3_k127_2950374_4	1499967.BAYZ01000088_gene5144	6.814e-16	85.0	COG2172@1|root,COG2172@2|Bacteria,2NQ1S@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma regulatory factor (Ser Thr protein kinase)	rsbW	-	2.7.11.1	ko:K04757,ko:K06379,ko:K08282	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SX3_k127_2950374_1	1379698.RBG1_1C00001G0632	4.089e-27	119.0	COG1366@1|root,COG1366@2|Bacteria,2NRCS@2323|unclassified Bacteria	2|Bacteria	T	STAS domain	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SX3_k127_2950374_0	1345697.M493_05785	1.352e-92	317.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,1WFGB@129337|Geobacillus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SX3_k127_2950374_3	1123239.KB898623_gene933	1.759e-23	107.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli	91061|Bacilli	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SX3_k127_2950374_2	861299.J421_3049	7.145e-24	106.0	COG1734@1|root,COG1734@2|Bacteria,1ZTP9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SX3_k127_2950374_5	487796.Flav2ADRAFT_0642	2.328e-13	72.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1HX3Y@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SX3_k127_2953830_0	909663.KI867150_gene1667	2.088e-25	120.0	COG3206@1|root,COG3206@2|Bacteria,1QUY4@1224|Proteobacteria,42RD1@68525|delta/epsilon subdivisions,2WMV4@28221|Deltaproteobacteria,2MQDI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	G-rich domain on putative tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
SX3_k127_2953830_2	298386.PBPRA0357	7.352e-09	68.0	COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,1RPTR@1236|Gammaproteobacteria,1XTJN@135623|Vibrionales	135623|Vibrionales	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	exoQ	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SX3_k127_2953830_1	448385.sce2971	1.3e-17	93.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,434QI@68525|delta/epsilon subdivisions,2X8Z6@28221|Deltaproteobacteria,2Z152@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2957582_4	517417.Cpar_1547	3.924e-22	98.0	COG0681@1|root,COG0681@2|Bacteria,1FDIZ@1090|Chlorobi	1090|Chlorobi	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SX3_k127_2957582_2	1379698.RBG1_1C00001G0425	3.185e-57	205.0	COG0681@1|root,COG0681@2|Bacteria,2NPIA@2323|unclassified Bacteria	2|Bacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SX3_k127_2957582_5	1379698.RBG1_1C00001G0229	0.0002622	52.0	2BIY5@1|root,32D6E@2|Bacteria,2NRW7@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_2957582_3	479434.Sthe_1579	4.942e-37	150.0	COG0251@1|root,COG0251@2|Bacteria,2G6XT@200795|Chloroflexi,27YDZ@189775|Thermomicrobia	189775|Thermomicrobia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SX3_k127_2957582_0	880073.Calab_0773	1.479e-238	753.0	COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
SX3_k127_2957582_1	143224.JQMD01000002_gene1021	3.173e-81	281.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1HWVH@117743|Flavobacteriia	976|Bacteroidetes	G	Phosphoglucosamine mutase	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SX3_k127_2958500_1	1163617.SCD_n02203	1.642e-57	228.0	COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,2VQJE@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
SX3_k127_2958500_0	1519464.HY22_09345	2.53e-146	477.0	COG1236@1|root,COG1236@2|Bacteria,1FER3@1090|Chlorobi	1090|Chlorobi	J	PFAM beta-lactamase domain protein	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
SX3_k127_2958500_2	313606.M23134_01619	2.002e-14	82.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes	976|Bacteroidetes	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
SX3_k127_2958888_0	1267533.KB906736_gene845	5.005e-189	614.0	COG0178@1|root,COG0178@2|Bacteria,3Y3PA@57723|Acidobacteria,2JISM@204432|Acidobacteriia	204432|Acidobacteriia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SX3_k127_2963277_1	335543.Sfum_3060	6.465e-10	69.0	2CC24@1|root,32VJT@2|Bacteria,1N5Y6@1224|Proteobacteria,42UPP@68525|delta/epsilon subdivisions,2WQ6U@28221|Deltaproteobacteria,2MSB1@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
SX3_k127_2963277_0	700598.Niako_4096	1.615e-31	135.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1IT79@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
SX3_k127_2992842_0	469371.Tbis_0702	2.68e-38	158.0	COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,4E356@85010|Pseudonocardiales	201174|Actinobacteria	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
SX3_k127_2992842_1	1128421.JAGA01000001_gene2111	2.545e-16	83.0	COG0157@1|root,COG0157@2|Bacteria,2NP3F@2323|unclassified Bacteria	2|Bacteria	H	Belongs to the NadC ModD family	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0030312,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SX3_k127_2994937_0	247490.KSU1_C0449	1.873e-45	183.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
SX3_k127_2994937_1	945713.IALB_2117	1.55e-06	61.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C10,Phage-tail_3,Prophage_tail,SLH
SX3_k127_2998406_1	398720.MED217_12309	1.01e-53	197.0	COG0823@1|root,COG1262@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1262@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1HZ0Y@117743|Flavobacteriia,2XKCW@283735|Leeuwenhoekiella	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PD40,Peptidase_S9
SX3_k127_2998406_0	1047013.AQSP01000092_gene317	4.799e-64	226.0	COG0778@1|root,COG0778@2|Bacteria,2NR7M@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SX3_k127_3008572_0	1265505.ATUG01000001_gene3174	2.625e-136	445.0	COG1042@1|root,COG1042@2|Bacteria,1R8Q6@1224|Proteobacteria,42NR2@68525|delta/epsilon subdivisions,2WM2A@28221|Deltaproteobacteria,2MN2C@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_2,Succ_CoA_lig
SX3_k127_3012189_0	861299.J421_3561	4.634e-261	820.0	COG0556@1|root,COG0556@2|Bacteria,1ZSQS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SX3_k127_3012189_2	1121428.DESHY_80066___1	1.772e-19	101.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,24M2Q@186801|Clostridia,261QR@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SX3_k127_3012189_1	1121472.AQWN01000006_gene1706	4.096e-24	109.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,25ZYN@186807|Peptococcaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SX3_k127_3015613_1	744979.R2A130_0184	1.649e-28	117.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	MA20_30780	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SX3_k127_3015613_0	1121935.AQXX01000114_gene3272	1.274e-47	191.0	COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1XHQX@135619|Oceanospirillales	135619|Oceanospirillales	M	N-acetylmuramoyl-L-alanine amidase	amiB	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
SX3_k127_3015613_2	338963.Pcar_1000	1.063e-09	69.0	COG4856@1|root,COG4856@2|Bacteria,1REEU@1224|Proteobacteria,42RY2@68525|delta/epsilon subdivisions,2WNZH@28221|Deltaproteobacteria,43SGW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
SX3_k127_3015978_0	933262.AXAM01000016_gene190	2.005e-113	376.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria,2MI4N@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SX3_k127_30223_0	1121456.ATVA01000012_gene2804	1.5e-72	259.0	COG0438@1|root,COG0438@2|Bacteria,1MUYN@1224|Proteobacteria,43F2S@68525|delta/epsilon subdivisions,2X35V@28221|Deltaproteobacteria,2ME5E@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SX3_k127_30223_2	485918.Cpin_7286	0.0001669	51.0	2AFPJ@1|root,315RB@2|Bacteria,4PJWT@976|Bacteroidetes,1IUP5@117747|Sphingobacteriia	976|Bacteroidetes	S	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
SX3_k127_30223_1	247490.KSU1_A0088	5.13e-30	119.0	COG1085@1|root,COG1085@2|Bacteria,2IX2C@203682|Planctomycetes	203682|Planctomycetes	C	galactose-1-phosphate uridylyltransferase	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf,HIT
SX3_k127_3025478_0	234267.Acid_1540	5.006e-25	115.0	COG4798@1|root,COG4798@2|Bacteria,3Y5JR@57723|Acidobacteria	57723|Acidobacteria	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
SX3_k127_3033816_1	469371.Tbis_1489	5.759e-29	123.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4DYBT@85010|Pseudonocardiales	201174|Actinobacteria	L	Tyrosine recombinase XerD	xerD	GO:0008150,GO:0040007	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SX3_k127_3033816_0	1304880.JAGB01000001_gene365	4.113e-72	252.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SX3_k127_3048566_0	1121422.AUMW01000005_gene654	2.216e-75	261.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,260J1@186807|Peptococcaceae	186801|Clostridia	Q	PFAM Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SX3_k127_3048566_1	379066.GAU_1933	3.661e-14	76.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
SX3_k127_3049798_0	1318628.MARLIPOL_05410	6.11e-23	106.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,1SBB6@1236|Gammaproteobacteria,46B2G@72275|Alteromonadaceae	1236|Gammaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SX3_k127_3053766_1	1379698.RBG1_1C00001G1006	1.528e-49	186.0	COG0682@1|root,COG0682@2|Bacteria,2NPK2@2323|unclassified Bacteria	2|Bacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SX3_k127_3053766_0	1379698.RBG1_1C00001G1004	2.297e-87	300.0	COG0772@1|root,COG0772@2|Bacteria,2NNRP@2323|unclassified Bacteria	2|Bacteria	D	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SX3_k127_3064929_0	1125863.JAFN01000001_gene1583	1.389e-52	196.0	COG2404@1|root,COG2404@2|Bacteria,1QW0R@1224|Proteobacteria,43BQN@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	COG0618 Exopolyphosphatase-related proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3068381_0	344747.PM8797T_13802	2.136e-121	401.0	COG0577@1|root,COG0577@2|Bacteria,2J25K@203682|Planctomycetes	203682|Planctomycetes	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SX3_k127_3068381_1	595460.RRSWK_02598	4.596e-76	261.0	COG1136@1|root,COG1136@2|Bacteria,2J1YS@203682|Planctomycetes	203682|Planctomycetes	V	COG1136 ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SX3_k127_3068381_3	1408428.JNJP01000055_gene143	6.492e-25	109.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,42V3T@68525|delta/epsilon subdivisions,2WS3M@28221|Deltaproteobacteria,2MC9Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Helix-turn-helix domain	-	-	-	ko:K03892,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
SX3_k127_3068381_2	1047013.AQSP01000092_gene323	1.895e-50	181.0	COG0798@1|root,COG0798@2|Bacteria,2NNWJ@2323|unclassified Bacteria	2|Bacteria	P	Sodium Bile acid symporter family	arsB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
SX3_k127_3068661_1	1121413.JMKT01000001_gene1731	5.175e-12	69.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42PAC@68525|delta/epsilon subdivisions,2WKAD@28221|Deltaproteobacteria,2M8ZY@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SX3_k127_3068661_0	690850.Desaf_3621	2.635e-183	585.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SX3_k127_3074909_0	335543.Sfum_3920	1.157e-56	201.0	COG2220@1|root,COG2220@2|Bacteria,1QB9E@1224|Proteobacteria,42N7W@68525|delta/epsilon subdivisions,2WMED@28221|Deltaproteobacteria,2MQU6@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SX3_k127_3074909_1	886293.Sinac_3091	1.003e-26	116.0	COG1663@1|root,COG1663@2|Bacteria,2IXYX@203682|Planctomycetes	203682|Planctomycetes	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
SX3_k127_3075182_1	56780.SYN_00467	1.128e-12	70.0	COG1633@1|root,COG1633@2|Bacteria,1NG4N@1224|Proteobacteria,42W3T@68525|delta/epsilon subdivisions,2WREZ@28221|Deltaproteobacteria,2MRRS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SX3_k127_3075182_0	517418.Ctha_2098	1.578e-57	207.0	COG1028@1|root,COG1028@2|Bacteria,1FEYT@1090|Chlorobi	1090|Chlorobi	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SX3_k127_307941_1	324925.Ppha_0338	1.563e-41	155.0	COG0628@1|root,COG0628@2|Bacteria,1FEQH@1090|Chlorobi	1090|Chlorobi	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SX3_k127_307941_0	656024.FsymDg_1675	5.595e-127	423.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SX3_k127_3084366_2	941824.TCEL_01157	6.103e-42	159.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,36FX2@31979|Clostridiaceae	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SX3_k127_3084366_1	1121861.KB899918_gene3210	1.853e-89	312.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2TQX9@28211|Alphaproteobacteria,2JPQI@204441|Rhodospirillales	204441|Rhodospirillales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SX3_k127_3084366_0	632335.Calkr_1468	3.265e-90	302.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,42F1M@68295|Thermoanaerobacterales	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SX3_k127_3086400_0	309801.trd_A0767	8.409e-22	106.0	COG1268@1|root,COG1268@2|Bacteria,2GBUZ@200795|Chloroflexi,27YWE@189775|Thermomicrobia	189775|Thermomicrobia	S	BioY family	-	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SX3_k127_3092535_0	517418.Ctha_0502	4.58e-121	398.0	COG0577@1|root,COG0577@2|Bacteria,1FDCY@1090|Chlorobi	1090|Chlorobi	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
SX3_k127_3101645_1	575540.Isop_3200	5.641e-13	76.0	COG0438@1|root,COG0707@1|root,COG0438@2|Bacteria,COG0707@2|Bacteria,2IY70@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SX3_k127_3101645_0	693979.Bache_2592	6.589e-54	205.0	COG0110@1|root,COG0110@2|Bacteria,4NR4W@976|Bacteroidetes,2FV2C@200643|Bacteroidia,4ASWG@815|Bacteroidaceae	976|Bacteroidetes	S	Sugar-transfer associated ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
SX3_k127_3101645_2	1392489.JPOL01000002_gene3348	1.199e-06	61.0	COG0110@1|root,COG0110@2|Bacteria,4PMXR@976|Bacteroidetes	976|Bacteroidetes	S	Sugar-transfer associated ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
SX3_k127_3115242_1	221288.JH992901_gene4583	4.909e-07	56.0	COG0859@1|root,COG0859@2|Bacteria,1G432@1117|Cyanobacteria,1JHQY@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
SX3_k127_3115242_0	1379698.RBG1_1C00001G1033	3.339e-55	206.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	msbA	-	-	ko:K02021,ko:K06147,ko:K06148,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
SX3_k127_3121163_0	706587.Desti_3776	2.074e-48	181.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42PAH@68525|delta/epsilon subdivisions,2WKSM@28221|Deltaproteobacteria,2MS4X@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356,ko:K03503	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SX3_k127_3121163_1	195250.CM001776_gene2132	1.916e-27	113.0	298AC@1|root,2ZVFW@2|Bacteria,1GGPS@1117|Cyanobacteria	1117|Cyanobacteria	S	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SX3_k127_3121163_2	864051.BurJ1DRAFT_1932	3.579e-26	109.0	COG3514@1|root,COG3514@2|Bacteria,1NAV1@1224|Proteobacteria,2VX5C@28216|Betaproteobacteria	28216|Betaproteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3121163_3	1191523.MROS_2088	9.597e-15	78.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_43
SX3_k127_3144640_0	706587.Desti_1873	4.204e-32	137.0	COG1453@1|root,COG1453@2|Bacteria,1RAU3@1224|Proteobacteria,43A0M@68525|delta/epsilon subdivisions,2X9UN@28221|Deltaproteobacteria,2MS7U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
SX3_k127_3154664_1	879212.DespoDRAFT_02420	1.814e-65	224.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2WIKW@28221|Deltaproteobacteria,2MHKB@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
SX3_k127_3154664_0	880072.Desac_2119	7.53e-102	337.0	COG1148@1|root,COG1148@2|Bacteria,1RB0H@1224|Proteobacteria,42QQV@68525|delta/epsilon subdivisions,2WN7E@28221|Deltaproteobacteria,2MRI3@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SX3_k127_316361_0	1297742.A176_07059	2.201e-43	166.0	COG0457@1|root,COG0457@2|Bacteria,1NTKG@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_316361_1	1131462.DCF50_p1146	1.729e-39	150.0	COG1109@1|root,COG1109@2|Bacteria,1TS6S@1239|Firmicutes,2491F@186801|Clostridia,260X1@186807|Peptococcaceae	186801|Clostridia	G	alpha beta alpha domain I	manB	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SX3_k127_3181774_0	335543.Sfum_2263	1.265e-70	241.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,42MTN@68525|delta/epsilon subdivisions,2WJAI@28221|Deltaproteobacteria,2MQUJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SX3_k127_3183016_0	639030.JHVA01000001_gene3308	1.466e-57	207.0	COG4152@1|root,COG4152@2|Bacteria,3Y2NV@57723|Acidobacteria,2JHVX@204432|Acidobacteriia	204432|Acidobacteriia	S	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SX3_k127_3183016_1	379066.GAU_3054	3.845e-16	86.0	COG1668@1|root,COG1668@2|Bacteria,1ZTID@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SX3_k127_3194290_4	1410653.JHVC01000008_gene2999	0.000134	47.0	COG1005@1|root,COG1005@2|Bacteria,1TQNU@1239|Firmicutes,25E6Z@186801|Clostridia,36EBY@31979|Clostridiaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SX3_k127_3194290_1	673860.AciM339_1163	3.812e-52	191.0	COG3260@1|root,arCOG01553@2157|Archaea,2Y8IV@28890|Euryarchaeota,3F3AA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Belongs to the complex I 20 kDa subunit family	-	-	1.12.7.2	ko:K18023	-	-	R00019	-	ko00000,ko01000	-	-	-	Oxidored_q6
SX3_k127_3194290_2	867903.ThesuDRAFT_02258	1.95e-13	78.0	COG0852@1|root,COG0852@2|Bacteria,1UFNI@1239|Firmicutes,24QZN@186801|Clostridia	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SX3_k127_3194290_0	521045.Kole_0568	2.924e-134	438.0	COG3261@1|root,COG3261@2|Bacteria	2|Bacteria	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_49kDa,NiFeSe_Hases
SX3_k127_3194290_3	338966.Ppro_0588	2.453e-10	71.0	COG1009@1|root,COG1009@2|Bacteria,1QV11@1224|Proteobacteria,43CGR@68525|delta/epsilon subdivisions,2X7RW@28221|Deltaproteobacteria	1224|Proteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
SX3_k127_3198441_0	243231.GSU1939	4.47e-66	243.0	COG0642@1|root,COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2206@2|Bacteria,1NSAV@1224|Proteobacteria,42Z68@68525|delta/epsilon subdivisions,2WURV@28221|Deltaproteobacteria,43U68@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD_5,HisKA
SX3_k127_3208906_0	744872.Spica_1837	6.308e-88	302.0	COG1592@1|root,COG1592@2|Bacteria,2J5MR@203691|Spirochaetes	203691|Spirochaetes	C	Rubrerythrin	rbr	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SX3_k127_3208906_3	626939.HMPREF9443_01490	3.937e-08	65.0	COG2608@1|root,COG2608@2|Bacteria,1TU9H@1239|Firmicutes,4H8T9@909932|Negativicutes	909932|Negativicutes	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
SX3_k127_3208906_1	1232410.KI421421_gene3809	3.483e-86	300.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2WJPP@28221|Deltaproteobacteria,43S3G@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
SX3_k127_3208906_2	706587.Desti_2516	7.543e-66	231.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2WPRX@28221|Deltaproteobacteria,2MQMZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
SX3_k127_3210208_0	313628.LNTAR_11816	3.33e-12	76.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Phosphodiest
SX3_k127_3219141_0	1449126.JQKL01000009_gene356	5.103e-54	195.0	COG1924@1|root,COG1924@2|Bacteria	2|Bacteria	I	4 iron, 4 sulfur cluster binding	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SX3_k127_3221376_1	880073.Calab_1595	2.941e-67	231.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SX3_k127_3221376_0	398512.JQKC01000001_gene2200	3.906e-97	333.0	COG5297@1|root,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Beta-lactamase,CBM60,CBM_2,Cellulase,DUF1593,PSCyt3,fn3
SX3_k127_3229072_1	552811.Dehly_0563	5.708e-61	213.0	COG0426@1|root,COG0426@2|Bacteria,2G9HN@200795|Chloroflexi	200795|Chloroflexi	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3229072_0	1304874.JAFY01000007_gene1691	8.866e-230	724.0	COG0369@1|root,COG1151@2|Bacteria,3TA79@508458|Synergistetes	508458|Synergistetes	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
SX3_k127_3232181_0	926569.ANT_26090	2.618e-59	220.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_trans_4_5,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SX3_k127_3232181_1	272558.10173265	4.32e-20	91.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,4HKSY@91061|Bacilli,1ZGHU@1386|Bacillus	91061|Bacilli	K	GntR family transcriptional regulator	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SX3_k127_3232572_2	1121405.dsmv_1836	4.304e-134	435.0	COG1181@1|root,COG1181@2|Bacteria,1MX3I@1224|Proteobacteria,42SA1@68525|delta/epsilon subdivisions,2WNIR@28221|Deltaproteobacteria,2MIAX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
SX3_k127_3232572_0	530564.Psta_3379	1.902e-177	567.0	COG1509@1|root,COG1509@2|Bacteria,2IYGS@203682|Planctomycetes	203682|Planctomycetes	C	lysine 2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,LAM_C,Radical_SAM
SX3_k127_3232572_3	243365.CV_0365	6.438e-134	443.0	COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,2VM0X@28216|Betaproteobacteria,2KSQI@206351|Neisseriales	206351|Neisseriales	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
SX3_k127_3232572_1	247490.KSU1_C0357	3.606e-161	516.0	COG1640@1|root,COG1640@2|Bacteria,2IXJJ@203682|Planctomycetes	203682|Planctomycetes	G	4-alpha-glucanotransferase	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SX3_k127_3236702_7	555088.DealDRAFT_2056	1.575e-29	120.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,42JJZ@68298|Syntrophomonadaceae	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SX3_k127_3236702_4	879305.HMPREF9290_0787	1.446e-49	181.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,22GIV@1570339|Peptoniphilaceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SX3_k127_3236702_6	1307761.L21SP2_0160	1.576e-37	144.0	COG0103@1|root,COG0103@2|Bacteria,2J8A0@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SX3_k127_3236702_0	1122216.AUHW01000009_gene1690	1.153e-84	288.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H1Z4@909932|Negativicutes	909932|Negativicutes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SX3_k127_3236702_2	935948.KE386494_gene260	3.43e-76	260.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,42EMG@68295|Thermoanaerobacterales	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SX3_k127_3236702_1	517418.Ctha_0527	1.496e-80	276.0	COG0528@1|root,COG0528@2|Bacteria,1FD6T@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SX3_k127_3236702_3	1307759.JOMJ01000003_gene241	3.202e-50	196.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2WNMN@28221|Deltaproteobacteria,2M8XC@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SX3_k127_3236702_5	234267.Acid_3241	8.496e-45	170.0	COG0020@1|root,COG0020@2|Bacteria,3Y485@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SX3_k127_3236962_1	1449976.KALB_8089	6.941e-40	150.0	COG3877@1|root,COG3877@2|Bacteria,2IJTS@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
SX3_k127_3236962_2	311424.DhcVS_526	2.671e-24	107.0	2DRM1@1|root,33C8J@2|Bacteria,2GATW@200795|Chloroflexi,34DBZ@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3236962_0	1111069.TCCBUS3UF1_17270	2.816e-56	205.0	COG1572@1|root,COG1572@2|Bacteria,1WM7M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
SX3_k127_3264053_2	761193.Runsl_4607	0.0002699	44.0	2EIUI@1|root,33CJV@2|Bacteria,4NYR6@976|Bacteroidetes,47T08@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3264053_0	644282.Deba_2013	8.426e-21	107.0	COG0745@1|root,COG2203@1|root,COG2206@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,Response_reg
SX3_k127_3269430_0	1118054.CAGW01000007_gene3842	1.138e-53	201.0	COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,4HB9F@91061|Bacilli	91061|Bacilli	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SX3_k127_3269430_1	861299.J421_1463	2.268e-29	128.0	COG2091@1|root,COG2091@2|Bacteria,1ZUPU@142182|Gemmatimonadetes	2|Bacteria	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SX3_k127_3270175_0	177437.HRM2_25370	5.704e-104	349.0	COG0535@1|root,COG0535@2|Bacteria,1RAHK@1224|Proteobacteria,42PBP@68525|delta/epsilon subdivisions,2WKMH@28221|Deltaproteobacteria,2MMKJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SX3_k127_3270175_2	633697.EubceDRAFT1_1001	1.088e-45	179.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia,25ZDW@186806|Eubacteriaceae	186801|Clostridia	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SX3_k127_3270175_3	762982.HMPREF9442_01886	8.03e-45	168.0	COG0778@1|root,COG0778@2|Bacteria,4NPZV@976|Bacteroidetes,2FNIP@200643|Bacteroidia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SX3_k127_3270175_1	56780.SYN_00357	2.573e-52	197.0	COG1351@1|root,COG1351@2|Bacteria,1QF4I@1224|Proteobacteria,43A0P@68525|delta/epsilon subdivisions,2X9Q1@28221|Deltaproteobacteria,2MSCD@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Thymidylate synthase complementing protein	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SX3_k127_3270897_1	404589.Anae109_1581	1.356e-08	61.0	COG0425@1|root,COG0425@2|Bacteria,1N08X@1224|Proteobacteria,42RUG@68525|delta/epsilon subdivisions,2WNNK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	yedF	-	-	-	-	-	-	-	-	-	-	-	DrsE,TusA
SX3_k127_3270897_0	880073.Calab_3409	3.765e-31	132.0	COG3330@1|root,COG3330@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4912)	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	DUF4912,PBP_like_2
SX3_k127_3273282_0	269799.Gmet_1512	2.041e-29	125.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,42PY0@68525|delta/epsilon subdivisions,2WJ2Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SX3_k127_3277809_0	309801.trd_0331	3.084e-152	490.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,27XUB@189775|Thermomicrobia	189775|Thermomicrobia	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SX3_k127_3282798_2	596329.HMPREF0631_1591	1.663e-05	48.0	COG1014@1|root,COG1014@2|Bacteria,1V1DT@1239|Firmicutes,25DIA@186801|Clostridia,25TAY@186804|Peptostreptococcaceae	186801|Clostridia	C	indolepyruvate ferredoxin oxidoreductase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	POR
SX3_k127_3282798_1	945713.IALB_0884	2.119e-24	116.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SX3_k127_3282798_0	247490.KSU1_C0449	3.143e-44	176.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
SX3_k127_3291609_2	574087.Acear_2185	3.618e-62	222.0	COG1212@1|root,COG1212@2|Bacteria,1TQU3@1239|Firmicutes,24H2B@186801|Clostridia,3WAKF@53433|Halanaerobiales	186801|Clostridia	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
SX3_k127_3291609_1	1125863.JAFN01000001_gene1785	1.148e-73	252.0	COG1838@1|root,COG1838@2|Bacteria,1RCSV@1224|Proteobacteria,42NRW@68525|delta/epsilon subdivisions,2X5RX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit	-	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
SX3_k127_3291609_0	1121430.JMLG01000006_gene1701	2.01e-109	366.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,26044@186807|Peptococcaceae	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, alpha	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
SX3_k127_3291609_3	909663.KI867151_gene3156	5.732e-58	209.0	COG2220@1|root,COG2220@2|Bacteria,1QB9E@1224|Proteobacteria,42N7W@68525|delta/epsilon subdivisions,2WNMC@28221|Deltaproteobacteria,2MQPI@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SX3_k127_3291609_4	46234.ANA_C10544	3.983e-32	127.0	COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria,1HNYF@1161|Nostocales	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SX3_k127_3291609_5	861299.J421_3337	3.007e-17	83.0	COG0261@1|root,COG0261@2|Bacteria,1ZTS8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SX3_k127_3292201_0	517418.Ctha_1405	7.002e-21	104.0	COG4591@1|root,COG4591@2|Bacteria,1FECJ@1090|Chlorobi	1090|Chlorobi	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SX3_k127_3308850_0	237368.SCABRO_01504	1.875e-102	342.0	COG0659@1|root,COG0659@2|Bacteria,2IX8K@203682|Planctomycetes	203682|Planctomycetes	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	-
SX3_k127_3309875_0	880073.Calab_1105	2.182e-25	124.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713,ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.33.1	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Peptidase_S8,Pkinase,VCBS
SX3_k127_3320616_3	2754.EH55_01870	1.041e-28	119.0	COG1180@1|root,COG1180@2|Bacteria,3T9PA@508458|Synergistetes	508458|Synergistetes	C	TIGRFAM glycyl-radical enzyme activating protein family	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
SX3_k127_3320616_0	1408473.JHXO01000001_gene2217	1.892e-256	817.0	COG3250@1|root,COG3250@2|Bacteria,4NE7H@976|Bacteroidetes,2FN2H@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 2, sugar binding domain protein	csxA_2	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_N
SX3_k127_3320616_4	382464.ABSI01000011_gene2441	5.386e-05	55.0	COG1572@1|root,COG3210@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,46XF9@74201|Verrucomicrobia,2IVRE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	QU	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3320616_2	319236.JCM19294_398	6.039e-31	125.0	COG0662@1|root,COG0662@2|Bacteria,4NS6V@976|Bacteroidetes,1I30K@117743|Flavobacteriia,3HKGJ@363408|Nonlabens	976|Bacteroidetes	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SX3_k127_3320616_1	243231.GSU0751	3.695e-73	250.0	COG5423@1|root,COG5423@2|Bacteria,1N9C0@1224|Proteobacteria,42W42@68525|delta/epsilon subdivisions,2WR81@28221|Deltaproteobacteria,43TPZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
SX3_k127_3326843_1	525909.Afer_1255	2.355e-09	63.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,4CNZD@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SX3_k127_3326843_0	1254432.SCE1572_18080	3.551e-21	100.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,434QI@68525|delta/epsilon subdivisions,2X8Z6@28221|Deltaproteobacteria,2Z152@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3327232_0	869213.JCM21142_41386	6.823e-35	141.0	COG2043@1|root,COG2043@2|Bacteria	2|Bacteria	C	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
SX3_k127_3327232_1	1121468.AUBR01000004_gene170	1.164e-17	89.0	COG1633@1|root,COG1633@2|Bacteria,1VHC3@1239|Firmicutes,24RIG@186801|Clostridia	186801|Clostridia	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SX3_k127_3342759_0	765420.OSCT_2611	2.937e-104	346.0	COG0309@1|root,COG0309@2|Bacteria,2G5MV@200795|Chloroflexi,376G0@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM hydrogenase expression formation protein HypE	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
SX3_k127_3342759_1	1408473.JHXO01000008_gene2655	1.066e-07	53.0	COG0330@1|root,COG0330@2|Bacteria,4NH8V@976|Bacteroidetes,2FQPC@200643|Bacteroidia	976|Bacteroidetes	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SX3_k127_3353439_2	880073.Calab_0921	4.018e-16	93.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
SX3_k127_3353439_0	247490.KSU1_C0449	1.667e-82	298.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
SX3_k127_3353439_1	247490.KSU1_D1009	7.42e-24	106.0	COG1618@1|root,COG1618@2|Bacteria	2|Bacteria	F	nucleotide phosphatase activity, acting on free nucleotides	mobA	-	2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34	ko:K00943,ko:K02013,ko:K02017,ko:K03574,ko:K03752,ko:K06928	ko00230,ko00240,ko00730,ko00790,ko01100,ko02010,map00230,map00240,map00730,map00790,map01100,map02010	M00053,M00189,M00240	R00086,R00615,R02094,R02098,R11581	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.14,3.A.1.8	-	-	DUF2478,NTPase_1
SX3_k127_3355123_1	1379270.AUXF01000005_gene825	7.809e-58	214.0	COG0196@1|root,COG0196@2|Bacteria,1ZSM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SX3_k127_3355123_3	246194.CHY_1760	2.217e-29	121.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,42GTG@68295|Thermoanaerobacterales	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SX3_k127_3355123_0	945713.IALB_0644	2.759e-218	698.0	COG1185@1|root,COG1185@2|Bacteria	2|Bacteria	J	polyribonucleotide nucleotidyltransferase activity	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SX3_k127_3355123_2	429009.Adeg_1653	1.019e-45	172.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,42ERN@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM peptidase M16 domain protein	ymxG	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SX3_k127_3357242_1	500637.PROVRUST_07327	1.807e-07	55.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,3Z795@586|Providencia	1236|Gammaproteobacteria	M	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	bepA	GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
SX3_k127_3357242_0	1379698.RBG1_1C00001G0312	8.704e-159	505.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SX3_k127_3362696_2	459349.CLOAM1790	2.895e-21	96.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
SX3_k127_3362696_0	1408473.JHXO01000001_gene2146	3.679e-57	206.0	COG1453@1|root,COG1453@2|Bacteria,4NJU2@976|Bacteroidetes,2G2UD@200643|Bacteroidia	976|Bacteroidetes	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
SX3_k127_3362696_1	1408473.JHXO01000012_gene274	3.817e-24	109.0	COG1453@1|root,COG1453@2|Bacteria,4NGCW@976|Bacteroidetes,2FPG8@200643|Bacteroidia	976|Bacteroidetes	S	Tat pathway signal sequence domain protein	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
SX3_k127_3363789_0	247490.KSU1_C0449	3.033e-100	349.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
SX3_k127_3363789_1	945713.IALB_1477	7.651e-11	75.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
SX3_k127_3374936_1	861299.J421_2657	5.665e-40	169.0	COG5492@1|root,COG5492@2|Bacteria,1ZSW8@142182|Gemmatimonadetes	2|Bacteria	N	domain, Protein	-	-	3.2.1.4,3.4.17.14	ko:K01179,ko:K07260,ko:K13735	ko00500,ko00550,ko01100,ko01502,ko02020,ko05100,map00500,map00550,map01100,map01502,map02020,map05100	M00651	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	GH5,GH9	-	Big_1,Big_2,Glug,IAT_beta,Invasin_D3,LysM,Mfa_like_1,SLH
SX3_k127_3374936_0	1304888.ATWF01000001_gene1814	6.766e-57	211.0	COG2204@1|root,COG2204@2|Bacteria,2GGCG@200930|Deferribacteres	200930|Deferribacteres	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02667,ko:K07715	ko02020,ko02024,map02020,map02024	M00501,M00502	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
SX3_k127_3381209_1	313628.LNTAR_05441	2.247e-22	105.0	COG0457@1|root,COG0457@2|Bacteria	313628.LNTAR_05441|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3381209_0	1121097.JCM15093_668	3.26e-65	232.0	COG3579@1|root,COG3579@2|Bacteria,4NJ3J@976|Bacteroidetes,2FMZY@200643|Bacteroidia,4AM6R@815|Bacteroidaceae	976|Bacteroidetes	E	Peptidase C1-like family	pepC	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1_2
SX3_k127_3394322_1	648996.Theam_1191	1.068e-68	237.0	COG0177@1|root,COG0177@2|Bacteria,2G3TX@200783|Aquificae	200783|Aquificae	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SX3_k127_3394322_0	1168034.FH5T_01400	1.403e-110	377.0	COG2304@1|root,COG2304@2|Bacteria,4NFNQ@976|Bacteroidetes,2FMMK@200643|Bacteroidia	976|Bacteroidetes	S	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
SX3_k127_3394322_3	604354.TSIB_1892	1.601e-18	93.0	COG1633@1|root,arCOG01103@2157|Archaea,2Y1BE@28890|Euryarchaeota,243JF@183968|Thermococci	183968|Thermococci	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SX3_k127_3394322_2	56780.SYN_00467	1.878e-37	148.0	COG1633@1|root,COG1633@2|Bacteria,1NG4N@1224|Proteobacteria,42W3T@68525|delta/epsilon subdivisions,2WREZ@28221|Deltaproteobacteria,2MRRS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SX3_k127_3397401_1	5722.XP_001308057.1	9.449e-21	104.0	COG0666@1|root,KOG4177@2759|Eukaryota	2759|Eukaryota	I	spectrin binding	-	-	-	ko:K15502,ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,DUF3447
SX3_k127_3397401_0	1499967.BAYZ01000090_gene4936	3.243e-42	164.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SX3_k127_3404359_0	880071.Fleli_2790	6.647e-58	214.0	COG1409@1|root,COG1409@2|Bacteria,4P3GR@976|Bacteroidetes	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SX3_k127_3404359_1	880073.Calab_0647	4.632e-19	95.0	COG1361@1|root,COG1595@1|root,COG1361@2|Bacteria,COG1595@2|Bacteria,2NPVV@2323|unclassified Bacteria	2|Bacteria	K	GxGYxYP putative glycoside hydrolase C-terminal domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SX3_k127_3404359_2	267377.MMP0501	2.302e-05	54.0	COG3291@1|root,arCOG03396@2157|Archaea	2157|Archaea	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	A2M_comp,CARDB,Prenyltrans,SQHop_cyclase_C,Thiol-ester_cl
SX3_k127_3404520_3	1499967.BAYZ01000019_gene6321	2.7e-32	129.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	MIase
SX3_k127_3404520_2	906968.Trebr_1004	8.591e-47	175.0	COG2249@1|root,COG2249@2|Bacteria,2J89Z@203691|Spirochaetes	203691|Spirochaetes	C	NADPH-dependent FMN reductase	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_2
SX3_k127_3404520_1	1128421.JAGA01000002_gene938	1.443e-68	245.0	COG0302@1|root,COG0302@2|Bacteria,2NPAT@2323|unclassified Bacteria	2|Bacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SX3_k127_3404520_0	1499967.BAYZ01000102_gene3560	1.774e-148	480.0	COG1092@1|root,COG1092@2|Bacteria,2NPFM@2323|unclassified Bacteria	2|Bacteria	J	S-adenosylmethionine-dependent methyltransferase	rlmI	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.173,2.1.1.191,2.1.1.264	ko:K06969,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
SX3_k127_3412005_3	555079.Toce_1053	7.399e-46	169.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,42ER1@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SX3_k127_3412005_1	517417.Cpar_0130	7.364e-80	280.0	COG0331@1|root,COG0331@2|Bacteria,1FDMY@1090|Chlorobi	1090|Chlorobi	I	malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SX3_k127_3412005_2	243231.GSU1603	1.703e-75	263.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,43TTF@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	KR domain	fabG-2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SX3_k127_3412005_4	1234364.AMSF01000037_gene115	3.787e-27	112.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1X7EF@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SX3_k127_3412005_0	997346.HMPREF9374_0894	6.537e-152	495.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,27B4D@186824|Thermoactinomycetaceae	91061|Bacilli	IQ	Beta-ketoacyl synthase, C-terminal domain	fabF3	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SX3_k127_3412512_0	517418.Ctha_0821	9.303e-58	221.0	COG1559@1|root,COG1559@2|Bacteria,1FDN4@1090|Chlorobi	1090|Chlorobi	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SX3_k127_3412512_1	1267535.KB906767_gene1029	5.655e-21	100.0	COG0816@1|root,COG0816@2|Bacteria,3Y59A@57723|Acidobacteria,2JP2U@204432|Acidobacteriia	204432|Acidobacteriia	J	Likely ribonuclease with RNase H fold.	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SX3_k127_3412512_2	1121440.AUMA01000002_gene2265	2.692e-07	53.0	COG2172@1|root,COG2208@1|root,COG2770@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,COG2770@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2M7Z5@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Cache_3-Cache_2,HAMP,SpoIIE,dCache_1,dCache_2
SX3_k127_341654_1	589865.DaAHT2_2415	1.216e-62	217.0	COG1232@1|root,COG1232@2|Bacteria,1MX35@1224|Proteobacteria,42NE7@68525|delta/epsilon subdivisions,2WJ77@28221|Deltaproteobacteria,2MM3R@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
SX3_k127_341654_0	1379698.RBG1_1C00001G1680	6.362e-134	441.0	COG0513@1|root,COG0513@2|Bacteria,2NP0A@2323|unclassified Bacteria	2|Bacteria	JKL	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K05592,ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
SX3_k127_3418119_0	1047013.AQSP01000126_gene2740	4.508e-181	601.0	COG2866@1|root,COG2866@2|Bacteria,2NQNH@2323|unclassified Bacteria	2|Bacteria	E	Zinc carboxypeptidase	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
SX3_k127_3419479_0	909663.KI867151_gene2965	8.323e-148	473.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MR61@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, NADH-binding	-	-	1.12.1.3,1.6.5.3	ko:K00124,ko:K00335,ko:K18331	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
SX3_k127_3419479_1	909663.KI867151_gene2966	2.557e-93	315.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1NT36@1224|Proteobacteria,42ZEC@68525|delta/epsilon subdivisions,2WU3Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
SX3_k127_3421600_2	1297742.A176_02282	1.233e-39	154.0	2ESNI@1|root,33K73@2|Bacteria,1Q2MV@1224|Proteobacteria,4388I@68525|delta/epsilon subdivisions,2X3I7@28221|Deltaproteobacteria,2YW7A@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2378
SX3_k127_3421600_0	909663.KI867150_gene2168	9.09e-135	444.0	COG0519@1|root,COG0519@2|Bacteria,1NR5X@1224|Proteobacteria,42YTH@68525|delta/epsilon subdivisions,2WUIJ@28221|Deltaproteobacteria,2MR8H@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	GMP synthase C terminal domain	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GMP_synt_C,NAD_synthase
SX3_k127_3421600_1	1499967.BAYZ01000076_gene816	9.654e-69	236.0	COG1064@1|root,COG1064@2|Bacteria,2NP06@2323|unclassified Bacteria	2|Bacteria	S	Alcohol dehydrogenase GroES-like domain	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SX3_k127_3426466_1	1345697.M493_16200	1.543e-09	61.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,1WFYK@129337|Geobacillus	91061|Bacilli	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SX3_k127_3426466_2	880073.Calab_0883	0.0006183	48.0	COG2922@1|root,COG2922@2|Bacteria	2|Bacteria	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
SX3_k127_3426466_0	517417.Cpar_2019	3.718e-118	392.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1FD5Q@1090|Chlorobi	1090|Chlorobi	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SX3_k127_3429079_0	1122176.KB903550_gene4281	8.526e-33	145.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1J0XD@117747|Sphingobacteriia	976|Bacteroidetes	D	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
SX3_k127_3429697_0	880073.Calab_2084	2.798e-19	97.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C,FlgD_ig,Peptidase_S74
SX3_k127_3429697_1	1089544.KB912942_gene4067	0.0005809	42.0	COG0582@1|root,COG0582@2|Bacteria,2IHIW@201174|Actinobacteria,4E2P0@85010|Pseudonocardiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SX3_k127_3432159_2	880073.Calab_0913	4.345e-18	85.0	COG1523@1|root,COG1523@2|Bacteria	2|Bacteria	G	belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
SX3_k127_3432159_3	767817.Desgi_0077	5.964e-13	75.0	COG2009@1|root,COG2009@2|Bacteria,1VKGI@1239|Firmicutes,24VB1@186801|Clostridia	186801|Clostridia	C	TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SX3_k127_3432159_1	760142.Hipma_0138	1.561e-19	96.0	COG2142@1|root,COG2142@2|Bacteria,1Q5Y0@1224|Proteobacteria,4321V@68525|delta/epsilon subdivisions,2WX4X@28221|Deltaproteobacteria,2M79B@213113|Desulfurellales	28221|Deltaproteobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SX3_k127_3432159_0	335543.Sfum_2104	5.563e-36	139.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WJXY@28221|Deltaproteobacteria,2MRE3@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	succinate dehydrogenase or fumarate reductase, flavoprotein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SX3_k127_343489_4	1089547.KB913013_gene3292	8.536e-57	204.0	COG3590@1|root,COG3590@2|Bacteria,4NKGB@976|Bacteroidetes,47JNY@768503|Cytophagia	976|Bacteroidetes	O	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_343489_2	35754.JNYJ01000035_gene3839	1.453e-83	286.0	COG4249@1|root,COG4249@2|Bacteria,2IB3R@201174|Actinobacteria,4DIC8@85008|Micromonosporales	201174|Actinobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Peptidase_C14
SX3_k127_343489_3	1379270.AUXF01000001_gene2437	1.995e-76	284.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1ZUTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
SX3_k127_343489_1	1047013.AQSP01000089_gene1181	6.298e-115	400.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cyaJ	-	4.6.1.1	ko:K01768,ko:K02483	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_19,TPR_2,TPR_8
SX3_k127_343489_0	1379698.RBG1_1C00001G1218	1.3e-121	419.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
SX3_k127_3435706_2	459349.CLOAM0801	1.511e-24	109.0	COG1404@1|root,COG2133@1|root,COG2356@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG2356@2|Bacteria,2NREM@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHB_HEX_C_1,CHU_C,FlgD_ig,LTD,Malectin,VCBS,fn3
SX3_k127_3435706_0	945713.IALB_0042	1.983e-128	431.0	COG0297@1|root,COG0297@2|Bacteria	2|Bacteria	G	glycogen (starch) synthase activity	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
SX3_k127_3435706_1	1123376.AUIU01000015_gene483	1.08e-29	120.0	COG1085@1|root,COG1085@2|Bacteria,3J0ER@40117|Nitrospirae	40117|Nitrospirae	H	Galactose-1-phosphate uridyl transferase, N-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
SX3_k127_3443717_0	204669.Acid345_1213	2.561e-82	282.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria,2JIRS@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SX3_k127_3443717_1	1313304.CALK_0940	1.248e-11	69.0	COG0544@1|root,COG0544@2|Bacteria	2|Bacteria	D	peptidyl-prolyl cis-trans isomerase activity	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SX3_k127_3446498_0	1191523.MROS_1440	6.27e-122	400.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SX3_k127_3457677_1	1105031.HMPREF1141_2841	2.996e-15	82.0	COG0438@1|root,COG0438@2|Bacteria,1TSNT@1239|Firmicutes,248MH@186801|Clostridia,36EEX@31979|Clostridiaceae	186801|Clostridia	M	Group 1 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
SX3_k127_3457677_0	1278073.MYSTI_02808	8.517e-86	301.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria	1224|Proteobacteria	S	major pilin protein fima	MA20_16755	-	-	-	-	-	-	-	-	-	-	-	DUF1028
SX3_k127_3462852_0	756272.Plabr_1344	3.86e-58	209.0	COG2148@1|root,COG2148@2|Bacteria,2IX7E@203682|Planctomycetes	203682|Planctomycetes	M	involved in lipopolysaccharide	-	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
SX3_k127_3463287_1	761193.Runsl_5214	2.84e-17	88.0	2CCAQ@1|root,2Z8M7@2|Bacteria,4NE4K@976|Bacteroidetes,47K2T@768503|Cytophagia	976|Bacteroidetes	S	Family of unknown function (DUF5458)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5458
SX3_k127_3463287_2	1168289.AJKI01000035_gene3556	2.041e-14	78.0	2DKUK@1|root,30D8W@2|Bacteria,4NNND@976|Bacteroidetes,2G3DK@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3463287_0	1123277.KB893207_gene407	3.596e-57	221.0	COG3501@1|root,COG3501@2|Bacteria,4NFNC@976|Bacteroidetes,47NM3@768503|Cytophagia	976|Bacteroidetes	S	Phage late control gene D protein (GPD)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
SX3_k127_3463287_3	706436.HMPREF9074_09075	7.279e-05	50.0	COG3628@1|root,COG3628@2|Bacteria,4NVAH@976|Bacteroidetes,1I3GD@117743|Flavobacteriia,1ETEW@1016|Capnocytophaga	976|Bacteroidetes	S	Gene 25-like lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	GPW_gp25
SX3_k127_3474429_0	98439.AJLL01000095_gene4183	3.003e-195	624.0	COG3321@1|root,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1JJJW@1189|Stigonemataceae	1117|Cyanobacteria	Q	Ketoacyl-synthetase C-terminal extension	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,ketoacyl-synt
SX3_k127_3478994_3	1404245.CGLY_06695	2.573e-09	64.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,22JN1@1653|Corynebacteriaceae	201174|Actinobacteria	J	Belongs to the SUA5 family	ywlC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SX3_k127_3478994_2	537970.HCAN_0639	7.997e-35	144.0	COG0535@1|root,COG0535@2|Bacteria,1PEYS@1224|Proteobacteria,42SNS@68525|delta/epsilon subdivisions,2YQGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
SX3_k127_3478994_0	861299.J421_2641	1.168e-66	252.0	COG1519@1|root,COG1519@2|Bacteria,1ZSXB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
SX3_k127_3478994_1	1125863.JAFN01000001_gene536	7.962e-47	184.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42UES@68525|delta/epsilon subdivisions,2WQD1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SX3_k127_3485185_1	330779.Saci_2233	1.502e-08	58.0	COG0183@1|root,arCOG01279@2157|Archaea,2XQ2B@28889|Crenarchaeota	28889|Crenarchaeota	I	acetyl-CoA C-acyltransferase activity	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
SX3_k127_3485185_0	304371.MCP_0950	2.321e-35	148.0	COG0535@1|root,arCOG00938@2157|Archaea,2Y2J6@28890|Euryarchaeota,2NAEK@224756|Methanomicrobia	224756|Methanomicrobia	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
SX3_k127_3490283_1	883.DvMF_0672	1.435e-06	54.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,42R3N@68525|delta/epsilon subdivisions,2WMY8@28221|Deltaproteobacteria,2MAPG@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	TIGRFAM eight transmembrane protein EpsH	epsH	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
SX3_k127_3490283_0	933262.AXAM01000037_gene865	4.378e-20	102.0	COG1269@1|root,COG1269@2|Bacteria,1RF6T@1224|Proteobacteria,42RED@68525|delta/epsilon subdivisions,2WNV7@28221|Deltaproteobacteria,2MJYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
SX3_k127_3500985_2	240292.Ava_3226	1.398e-38	164.0	COG5002@1|root,COG5002@2|Bacteria,1FZWA@1117|Cyanobacteria,1HM49@1161|Nostocales	1117|Cyanobacteria	T	TIGRFAM PAS domain S-box	nblS	-	2.7.13.3	ko:K07769	ko02020,map02020	M00466	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
SX3_k127_3500985_3	42256.RradSPS_0256	1.431e-25	117.0	COG5002@1|root,COG5002@2|Bacteria,2I3V4@201174|Actinobacteria,4CR2M@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM ATP-binding region, ATPase-like histidine kinase, HAMP region histidine kinase A-like PAS fold-4	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SX3_k127_3500985_1	340099.Teth39_0760	7.436e-87	299.0	COG2199@1|root,COG3706@2|Bacteria,1UHZ8@1239|Firmicutes,25E7W@186801|Clostridia,42FF0@68295|Thermoanaerobacterales	186801|Clostridia	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
SX3_k127_3500985_0	1121918.ARWE01000001_gene1565	5.359e-88	301.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,43S66@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Glycoprotease family	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SX3_k127_3500985_4	880073.Calab_0921	9.088e-17	94.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
SX3_k127_3503920_0	1121101.HMPREF1532_03733	8.328e-41	169.0	COG1361@1|root,COG1520@1|root,COG4870@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG4870@2|Bacteria,4NVQ3@976|Bacteroidetes,2G321@200643|Bacteroidia,4ATRZ@815|Bacteroidaceae	976|Bacteroidetes	MO	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,VCBS
SX3_k127_3515035_0	1232410.KI421428_gene1165	1.055e-162	524.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2WISV@28221|Deltaproteobacteria,43S1V@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	C-terminal, D2-small domain, of ClpB protein	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
SX3_k127_3515035_1	1089553.Tph_c10750	2.477e-28	115.0	COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,24FS4@186801|Clostridia,42G10@68295|Thermoanaerobacterales	186801|Clostridia	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
SX3_k127_3515119_2	944480.ATUV01000001_gene603	1.115e-45	168.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,42R4B@68525|delta/epsilon subdivisions,2WMZN@28221|Deltaproteobacteria,2M734@213113|Desulfurellales	28221|Deltaproteobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SX3_k127_3515119_1	1379698.RBG1_1C00001G1133	3.051e-60	220.0	COG1575@1|root,COG1575@2|Bacteria,2NPNN@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SX3_k127_3515119_0	522772.Dacet_1337	1.555e-71	246.0	COG1611@1|root,COG1611@2|Bacteria,2GEPC@200930|Deferribacteres	200930|Deferribacteres	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SX3_k127_35156_0	1197477.IA57_12090	4.108e-208	667.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SX3_k127_3537765_1	1301100.HG529277_gene1670	7.396e-05	53.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,36DN2@31979|Clostridiaceae	186801|Clostridia	D	Capsular exopolysaccharide family	ywqD	-	-	-	-	-	-	-	-	-	-	-	AAA_31,ParA,Wzz
SX3_k127_3537765_0	644968.DFW101_0101	1.865e-69	244.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42NNX@68525|delta/epsilon subdivisions,2WJ9P@28221|Deltaproteobacteria,2M9N2@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	secretion ATPase, PEP-CTERM locus subfamily	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
SX3_k127_3538206_1	316274.Haur_3817	7.299e-33	137.0	COG0697@1|root,COG0697@2|Bacteria,2G70T@200795|Chloroflexi,3762A@32061|Chloroflexia	32061|Chloroflexia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SX3_k127_3538206_0	1121405.dsmv_0026	1.792e-62	220.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2MJZR@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SX3_k127_3544429_0	1232410.KI421428_gene1054	3.65e-137	448.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SX3_k127_35474_1	391038.Bphy_0639	1.606e-05	54.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria,1K0WR@119060|Burkholderiaceae	28216|Betaproteobacteria	M	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
SX3_k127_35474_0	1453505.JASY01000002_gene2691	7.58e-08	66.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1HXXP@117743|Flavobacteriia,2NS6K@237|Flavobacterium	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3547923_0	643867.Ftrac_2139	4.131e-13	83.0	COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,47KV2@768503|Cytophagia	976|Bacteroidetes	M	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
SX3_k127_3549541_2	933262.AXAM01000011_gene1757	1.095e-92	314.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,2MJ2R@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SX3_k127_3549541_0	933262.AXAM01000011_gene1756	8.017e-129	425.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,2MJ3H@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
SX3_k127_3549541_1	1125863.JAFN01000001_gene2835	9.517e-119	404.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2
SX3_k127_3549541_3	673860.AciM339_0766	0.0001341	45.0	COG1014@1|root,arCOG01603@2157|Archaea,2XVFR@28890|Euryarchaeota,3F2RB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porC	-	1.2.7.1,1.2.7.7	ko:K00172,ko:K00189	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
SX3_k127_3555945_1	1192034.CAP_2692	8.228e-05	53.0	COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,4396X@68525|delta/epsilon subdivisions,2X4DR@28221|Deltaproteobacteria,2YYTQ@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,TPR_2
SX3_k127_3555945_0	382464.ABSI01000011_gene3173	1.58e-19	99.0	COG3049@1|root,COG3049@2|Bacteria	2|Bacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	AAT,AMPK1_CBM,CBAH
SX3_k127_3580676_1	243275.TDE_2401	7.216e-88	300.0	COG0451@1|root,COG0451@2|Bacteria,2J62J@203691|Spirochaetes	203691|Spirochaetes	M	NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SX3_k127_3580676_0	1144275.COCOR_04452	1.902e-243	767.0	COG1164@1|root,COG1164@2|Bacteria,1Q3C4@1224|Proteobacteria,4393F@68525|delta/epsilon subdivisions,2X49B@28221|Deltaproteobacteria,2YYJ7@29|Myxococcales	28221|Deltaproteobacteria	E	Oligoendopeptidase f	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3589116_1	596152.DesU5LDRAFT_2790	8.03e-07	51.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MG1U@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SX3_k127_3589116_0	1379698.RBG1_1C00001G1866	5.361e-54	200.0	COG2204@1|root,COG2204@2|Bacteria,2NQDH@2323|unclassified Bacteria	2|Bacteria	T	Sigma-54 interaction domain	fhlA	-	-	ko:K03413,ko:K13589	ko02020,ko02030,ko04112,map02020,map02030,map04112	M00506,M00512	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
SX3_k127_3596154_0	945713.IALB_0147	5.522e-30	135.0	COG2234@1|root,COG4412@1|root,COG2234@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.11.10,3.4.21.50	ko:K01337,ko:K05994,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Glyco_hydro_31,PA,Peptidase_M28,Peptidase_M6,Peptidase_S8,W_rich_C
SX3_k127_359904_1	1499967.BAYZ01000009_gene5286	2.366e-91	315.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
SX3_k127_359904_3	1499967.BAYZ01000009_gene5287	1.336e-21	99.0	COG0636@1|root,COG0636@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110,ko:K02124	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157,M00159	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1,3.A.2.2,3.A.2.3	-	-	ATP-synt_C
SX3_k127_359904_2	1123274.KB899427_gene3356	9.719e-23	100.0	COG1436@1|root,COG1436@2|Bacteria,2J8AJ@203691|Spirochaetes	203691|Spirochaetes	C	-ATPase subunit F	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
SX3_k127_359904_4	246969.TAM4_1195	2.092e-13	78.0	COG1390@1|root,arCOG00869@2157|Archaea,2XWGX@28890|Euryarchaeota,243A6@183968|Thermococci	183968|Thermococci	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
SX3_k127_359904_0	158189.SpiBuddy_1148	4.415e-237	745.0	COG1155@1|root,COG1155@2|Bacteria,2J5EF@203691|Spirochaetes	203691|Spirochaetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
SX3_k127_3599742_0	1121897.AUGO01000003_gene1760	9.548e-05	53.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,1HXHN@117743|Flavobacteriia,2NU9B@237|Flavobacterium	976|Bacteroidetes	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2
SX3_k127_3603877_1	706587.Desti_1348	2.118e-32	142.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,42PY0@68525|delta/epsilon subdivisions,2WJ2Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SX3_k127_3603877_0	224324.aq_542	1.406e-125	415.0	COG3635@1|root,COG3635@2|Bacteria	2|Bacteria	G	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity	apgM	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
SX3_k127_3610856_0	1379698.RBG1_1C00001G1432	2.554e-72	257.0	COG1196@1|root,COG1196@2|Bacteria,2NNYZ@2323|unclassified Bacteria	2|Bacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529,ko:K19171	-	-	-	-	ko00000,ko02048,ko03036	-	-	-	SMC_N,SMC_hinge
SX3_k127_3612280_0	880073.Calab_3036	1.504e-163	524.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria	2|Bacteria	EU	peptidase S9 prolyl oligopeptidase active site	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
SX3_k127_3612280_1	156889.Mmc1_2110	7.884e-60	230.0	COG1453@1|root,COG1453@2|Bacteria,1RAU3@1224|Proteobacteria	1224|Proteobacteria	S	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
SX3_k127_3626401_0	945713.IALB_2995	1.273e-09	70.0	COG4288@1|root,COG4288@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Big_5,CHU_C,FlgD_ig,LTD
SX3_k127_3626401_1	1043205.AFYF01000056_gene2578	4.006e-05	56.0	COG2374@1|root,COG2374@2|Bacteria,2I2E0@201174|Actinobacteria,4FFZJ@85021|Intrasporangiaceae	201174|Actinobacteria	M	Lamin Tail Domain	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
SX3_k127_3627768_1	1242864.D187_006687	5.096e-30	127.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2YUWE@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD3	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SX3_k127_3627768_0	1379698.RBG1_1C00001G1340	5.62e-72	260.0	COG2309@1|root,COG2309@2|Bacteria,2NPR4@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
SX3_k127_3637884_2	762983.HMPREF9444_00721	1.911e-10	65.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria,1Y4TR@135624|Aeromonadales	135624|Aeromonadales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SX3_k127_3637884_0	643867.Ftrac_3265	8.298e-21	105.0	COG1729@1|root,COG1729@2|Bacteria,4PMDK@976|Bacteroidetes,47Y26@768503|Cytophagia	976|Bacteroidetes	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3637884_1	1121918.ARWE01000001_gene3629	2.521e-11	76.0	COG1729@1|root,COG1729@2|Bacteria,1NE9U@1224|Proteobacteria,42W04@68525|delta/epsilon subdivisions,2WSHK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SX3_k127_3638788_0	452637.Oter_2020	4.667e-20	102.0	COG0683@1|root,COG0683@2|Bacteria,46UD1@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SX3_k127_3638788_1	404589.Anae109_1980	4.067e-07	59.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
SX3_k127_3641319_1	1519464.HY22_10230	1.828e-66	235.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1FEH6@1090|Chlorobi	1090|Chlorobi	GM	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SX3_k127_3641319_0	251229.Chro_0804	1.389e-99	336.0	COG0673@1|root,COG0673@2|Bacteria,1G1CZ@1117|Cyanobacteria,3VK5W@52604|Pleurocapsales	1117|Cyanobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SX3_k127_3641319_2	1122182.KB903814_gene3226	2.133e-60	218.0	COG0110@1|root,COG0110@2|Bacteria,2H5M0@201174|Actinobacteria,4DF0N@85008|Micromonosporales	201174|Actinobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SX3_k127_3641319_3	1214242.B446_14370	3.469e-09	67.0	COG0438@1|root,COG0438@2|Bacteria,2GNR8@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K19424	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SX3_k127_3659463_1	1328313.DS2_18493	1.13e-19	104.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,4677J@72275|Alteromonadaceae	1236|Gammaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SX3_k127_3659463_0	572546.Arcpr_0668	6.919e-30	121.0	COG0477@1|root,arCOG00143@2157|Archaea,2XUTR@28890|Euryarchaeota,245RD@183980|Archaeoglobi	183980|Archaeoglobi	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SX3_k127_366256_2	1123311.KB904455_gene433	4.247e-08	56.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SX3_k127_366256_1	1158294.JOMI01000009_gene1028	1.208e-14	80.0	COG3516@1|root,COG3516@2|Bacteria,4NMKM@976|Bacteroidetes,2FTM9@200643|Bacteroidia	976|Bacteroidetes	S	type VI secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	T6SS_VipA
SX3_k127_366256_0	553177.CAPSP0001_0036	1.341e-45	185.0	2CCAQ@1|root,2Z8M7@2|Bacteria,4NE4K@976|Bacteroidetes,1HYKG@117743|Flavobacteriia,1EQMN@1016|Capnocytophaga	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF5458
SX3_k127_3662754_1	1192034.CAP_0196	1.947e-42	160.0	COG3503@1|root,COG3503@2|Bacteria,1QQ9D@1224|Proteobacteria,431ME@68525|delta/epsilon subdivisions,2WWTB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
SX3_k127_3662754_0	1379270.AUXF01000001_gene2437	2.622e-88	301.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1ZUTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
SX3_k127_3665846_1	1415754.JQMK01000002_gene2681	1.227e-64	234.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,4645T@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	iYL1228.KPN_03597,ic_1306.c3945	polyprenyl_synt
SX3_k127_3665846_0	1121468.AUBR01000038_gene1958	3.623e-105	365.0	COG1180@1|root,COG1180@2|Bacteria,1TP46@1239|Firmicutes,248K9@186801|Clostridia,42F1Z@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SX3_k127_3665846_2	926561.KB900617_gene1797	6.897e-06	51.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,3WASC@53433|Halanaerobiales	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SX3_k127_3673530_0	644282.Deba_2013	7.638e-71	261.0	COG0745@1|root,COG2203@1|root,COG2206@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,Response_reg
SX3_k127_3673530_1	326427.Cagg_2395	1.347e-34	149.0	COG2203@1|root,COG2204@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG2206@2|Bacteria,2G6ND@200795|Chloroflexi,376W1@32061|Chloroflexia	32061|Chloroflexia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HD,Response_reg
SX3_k127_3685161_3	997346.HMPREF9374_2520	3.652e-19	93.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,27B4W@186824|Thermoactinomycetaceae	91061|Bacilli	L	RecF/RecN/SMC N terminal domain	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SX3_k127_3685161_4	690850.Desaf_1302	2.847e-06	57.0	COG5512@1|root,COG5512@2|Bacteria,1NDFM@1224|Proteobacteria,42W2X@68525|delta/epsilon subdivisions,2WR7J@28221|Deltaproteobacteria,2MB4N@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SX3_k127_3685161_1	1034347.CAHJ01000089_gene1667	8.007e-249	794.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,1ZBFI@1386|Bacillus	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SX3_k127_3685161_0	1379698.RBG1_1C00001G0278	1.675e-321	1005.0	COG0188@1|root,COG0188@2|Bacteria,2NNNR@2323|unclassified Bacteria	2|Bacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SX3_k127_3685161_2	518766.Rmar_2721	7.646e-106	358.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,1FIUG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SX3_k127_3686561_0	1047013.AQSP01000105_gene1438	8.414e-135	436.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SX3_k127_3686561_1	1047013.AQSP01000053_gene291	7.027e-91	309.0	COG0457@1|root,COG0491@1|root,COG0457@2|Bacteria,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SX3_k127_3692817_0	1273103.NM10_10580	2.841e-61	219.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4H2BC@909932|Negativicutes	909932|Negativicutes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SX3_k127_3692817_1	880073.Calab_3206	6.57e-36	144.0	COG0344@1|root,COG0344@2|Bacteria,2NPME@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SX3_k127_3692817_2	1303518.CCALI_00882	1.188e-31	128.0	COG0240@1|root,COG0240@2|Bacteria	2|Bacteria	I	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.1.1.94	ko:K00057,ko:K07175	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	iJN678.gpsA,iJN746.PP_4169	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SX3_k127_3696574_1	375286.mma_0411	1.242e-07	59.0	COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,2VIMD@28216|Betaproteobacteria,4733W@75682|Oxalobacteraceae	28216|Betaproteobacteria	MU	Outer membrane efflux protein	czcC	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SX3_k127_3696574_0	290397.Adeh_1019	8.423e-100	346.0	COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,42SYF@68525|delta/epsilon subdivisions,2WPNQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
SX3_k127_3709518_0	1121422.AUMW01000056_gene42	8.997e-91	312.0	COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,24CJP@186801|Clostridia,260KE@186807|Peptococcaceae	186801|Clostridia	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K06324	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SX3_k127_3709518_1	880073.Calab_0041	1.54e-22	110.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
SX3_k127_3711088_2	237368.SCABRO_03394	3.183e-23	112.0	COG0438@1|root,COG0438@2|Bacteria,2IY3T@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SX3_k127_3711088_0	357808.RoseRS_4077	8.184e-67	234.0	COG1208@1|root,COG1208@2|Bacteria,2G65W@200795|Chloroflexi,374YB@32061|Chloroflexia	200795|Chloroflexi	M	PFAM transferase hexapeptide repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
SX3_k127_3711088_1	595537.Varpa_0774	2.51e-51	186.0	COG0451@1|root,COG0451@2|Bacteria,1QX8V@1224|Proteobacteria,2WHP9@28216|Betaproteobacteria,4AK0F@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SX3_k127_3713962_0	1121405.dsmv_1869	2.917e-43	174.0	COG2768@1|root,COG2768@2|Bacteria,1MXMK@1224|Proteobacteria,42M2Z@68525|delta/epsilon subdivisions,2WIN6@28221|Deltaproteobacteria,2MI71@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF362)	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_4,Fer4_6,Fer4_7
SX3_k127_3717425_1	362418.IW19_23630	4.674e-17	86.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1HY1W@117743|Flavobacteriia,2NV4W@237|Flavobacterium	976|Bacteroidetes	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
SX3_k127_3717425_0	880072.Desac_0400	1.137e-139	451.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2WKFT@28221|Deltaproteobacteria,2MQ5J@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
SX3_k127_3725486_2	82995.CR62_23480	0.0004427	51.0	COG2244@1|root,COG2244@2|Bacteria,1MUN5@1224|Proteobacteria,1RRAJ@1236|Gammaproteobacteria,40218@613|Serratia	1236|Gammaproteobacteria	S	Polysaccharide biosynthesis protein	wzx	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SX3_k127_3725486_0	234267.Acid_7439	5.804e-69	241.0	COG1215@1|root,COG1215@2|Bacteria,3Y5K6@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SX3_k127_3725486_1	926550.CLDAP_35900	1.456e-18	91.0	COG2076@1|root,COG2076@2|Bacteria	2|Bacteria	P	Multidrug Resistance protein	arnF	-	-	-	-	-	-	-	-	-	-	-	EamA,Multi_Drug_Res
SX3_k127_3727622_1	401526.TcarDRAFT_0930	2.173e-23	111.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H3GM@909932|Negativicutes	909932|Negativicutes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
SX3_k127_3727622_0	573.JG24_30110	2.635e-51	189.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,1RNPQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SX3_k127_3730654_1	269799.Gmet_1396	4.112e-31	129.0	COG5000@1|root,COG5000@2|Bacteria,1QVAT@1224|Proteobacteria,43BPZ@68525|delta/epsilon subdivisions,2X717@28221|Deltaproteobacteria,43TK3@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Sensor histidine kinase PilS, PAS domain-containing	pilS	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4
SX3_k127_3730654_0	1379698.RBG1_1C00001G1210	5.473e-148	482.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K02667,ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00501,M00772	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
SX3_k127_3730654_2	1125863.JAFN01000001_gene2895	2.494e-10	69.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,42XTP@68525|delta/epsilon subdivisions,2WT04@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Belongs to the N-Me-Phe pilin family	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
SX3_k127_3732785_0	747365.Thena_0784	6.562e-188	614.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,42FKB@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SX3_k127_374760_0	742742.HMPREF9452_00269	7.241e-69	242.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4CU72@84998|Coriobacteriia	84998|Coriobacteriia	T	phosphate starvation-inducible protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SX3_k127_374760_1	880073.Calab_0220	4.458e-22	105.0	COG1652@1|root,COG1652@2|Bacteria,2NRPG@2323|unclassified Bacteria	2|Bacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398,LysM,SAM_adeno_trans,Y_phosphatase3
SX3_k127_3750440_0	1121468.AUBR01000034_gene1358	2.537e-99	329.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,42FIA@68295|Thermoanaerobacterales	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SX3_k127_3750440_1	1379270.AUXF01000006_gene179	9.722e-76	274.0	COG1703@1|root,COG1703@2|Bacteria,1ZT8J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SX3_k127_3750440_3	643648.Slip_0757	2.224e-53	194.0	COG2109@1|root,COG2109@2|Bacteria,1V70U@1239|Firmicutes,24JNB@186801|Clostridia,42K3H@68298|Syntrophomonadaceae	186801|Clostridia	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
SX3_k127_3750440_2	247490.KSU1_A0086	1.633e-67	252.0	COG0642@1|root,COG2205@2|Bacteria,2J4XW@203682|Planctomycetes	203682|Planctomycetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SX3_k127_375130_1	243231.GSU0031	5.965e-29	124.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,43TH8@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
SX3_k127_375130_0	1123376.AUIU01000012_gene1496	3.099e-30	123.0	COG0681@1|root,COG0681@2|Bacteria,3J0IP@40117|Nitrospirae	40117|Nitrospirae	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SX3_k127_3756099_0	1237149.C900_02937	5.248e-36	147.0	COG1262@1|root,COG1262@2|Bacteria,4NKVR@976|Bacteroidetes	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SX3_k127_3756099_1	1519464.HY22_11920	2.203e-21	106.0	COG3391@1|root,COG4412@1|root,COG3391@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	CARDB,FTP,He_PIG,NHL,PA,Peptidase_M30,Peptidase_M36,Peptidase_M6
SX3_k127_3756099_2	247490.KSU1_C0449	2.647e-18	97.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
SX3_k127_3757151_1	195253.Syn6312_3643	7.379e-18	89.0	COG0454@1|root,COG0456@2|Bacteria,1G5UI@1117|Cyanobacteria,1H0Y5@1129|Synechococcus	1117|Cyanobacteria	K	Acetyltransferase (GNAT) family	-	-	-	ko:K03828,ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SX3_k127_3757151_0	251221.35214834	1.626e-109	364.0	COG0448@1|root,COG0448@2|Bacteria,1G0IG@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.agp,iSbBS512_1146.agp	NTP_transferase
SX3_k127_3773899_0	760568.Desku_3183	9.386e-138	445.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,26059@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SX3_k127_3773899_1	498761.HM1_1343	6.591e-82	291.0	COG3869@1|root,COG3869@2|Bacteria,1TPBA@1239|Firmicutes,247SS@186801|Clostridia	186801|Clostridia	H	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
SX3_k127_3773899_3	1089553.Tph_c03700	2.778e-34	138.0	COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,24JE8@186801|Clostridia,42G0X@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM UvrB UvrC protein	mcsA	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
SX3_k127_3773899_2	1122176.KB903547_gene1064	5.749e-71	248.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1IPBQ@117747|Sphingobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
SX3_k127_3773899_4	1288826.MSNKSG1_07333	4.526e-08	54.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,4649Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SX3_k127_3783884_0	459349.CLOAM0891	2.355e-131	460.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_2,HATPase_c,PQQ_2,PQQ_3,Peptidase_C25,SLH,Y_Y_Y
SX3_k127_3783884_1	190650.CC_3572	8.634e-07	55.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2TU0G@28211|Alphaproteobacteria,2KITR@204458|Caulobacterales	204458|Caulobacterales	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SX3_k127_3785518_1	1121439.dsat_0909	3.074e-21	100.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2M8Z2@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
SX3_k127_3785518_0	401526.TcarDRAFT_1875	3.895e-91	321.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SX3_k127_3789911_0	459349.CLOAM0891	1.971e-97	342.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_2,HATPase_c,PQQ_2,PQQ_3,Peptidase_C25,SLH,Y_Y_Y
SX3_k127_3791269_0	1047013.AQSP01000134_gene1338	4.778e-155	501.0	COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria	2|Bacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
SX3_k127_3791269_2	555088.DealDRAFT_2256	3.474e-20	103.0	COG1410@1|root,COG1410@2|Bacteria,1V7JJ@1239|Firmicutes,24AE1@186801|Clostridia	186801|Clostridia	E	vitamin B12 dependent methionine synthase, activation	metH2	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
SX3_k127_3791269_3	574087.Acear_1072	1.547e-19	91.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,3WA7C@53433|Halanaerobiales	186801|Clostridia	H	PFAM Pterin binding enzyme	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SX3_k127_3791269_1	1499967.BAYZ01000181_gene4487	1.946e-29	123.0	COG0646@1|root,COG0646@2|Bacteria,2NP9A@2323|unclassified Bacteria	2|Bacteria	E	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
SX3_k127_3792536_2	1469557.JSWF01000029_gene3356	1.273e-41	163.0	2CESB@1|root,2Z8UZ@2|Bacteria,4NJSJ@976|Bacteroidetes,1I15D@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
SX3_k127_3792536_1	552811.Dehly_0101	5.013e-78	271.0	COG1313@1|root,COG1313@2|Bacteria,2G65I@200795|Chloroflexi,34CIH@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	-
SX3_k127_3792536_0	522373.Smlt4159	1.734e-96	344.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria	1224|Proteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	3.4.13.22,3.4.16.4	ko:K01286,ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Beta-lactamase
SX3_k127_3801225_5	219305.MCAG_00026	8.977e-05	49.0	COG5660@1|root,COG5660@2|Bacteria,2IHDZ@201174|Actinobacteria,4DD83@85008|Micromonosporales	201174|Actinobacteria	S	Putative zinc-finger	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	zf-HC2
SX3_k127_3801225_2	583355.Caka_1480	1.287e-23	107.0	COG1595@1|root,COG1595@2|Bacteria,46SZG@74201|Verrucomicrobia,3K9TR@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SX3_k127_3801225_0	880073.Calab_0865	9.059e-86	297.0	COG0491@1|root,COG0491@2|Bacteria,2NPRD@2323|unclassified Bacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	ytnP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SX3_k127_3801225_1	665959.HMPREF1013_00955	3.506e-33	136.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,4HKFQ@91061|Bacilli,1ZH9U@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
SX3_k127_3801225_4	1307761.L21SP2_0067	8.44e-14	74.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SX3_k127_3802053_0	760142.Hipma_1101	7.891e-30	124.0	COG0697@1|root,COG0697@2|Bacteria,1PIF3@1224|Proteobacteria,42SMV@68525|delta/epsilon subdivisions,2WPAJ@28221|Deltaproteobacteria,2M6F0@213113|Desulfurellales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SX3_k127_3802053_1	118173.KB235914_gene1270	2.578e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SX3_k127_3810707_1	1476583.DEIPH_ctg041orf0003	2.385e-20	101.0	COG4653@1|root,COG4653@2|Bacteria	2|Bacteria	G	Phage capsid family	xkdG	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S78,Phage_capsid
SX3_k127_3810707_2	136993.KB900626_gene2757	8.36e-19	96.0	COG3740@1|root,COG3740@2|Bacteria,1N2D8@1224|Proteobacteria,2UD3U@28211|Alphaproteobacteria,36YCB@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Caudovirus prohead serine protease	-	-	-	ko:K06904	-	-	-	-	ko00000	-	-	-	Peptidase_S78
SX3_k127_3810707_0	1116232.AHBF01000036_gene5641	8.214e-21	108.0	COG2369@1|root,COG4695@1|root,COG2369@2|Bacteria,COG4695@2|Bacteria	2|Bacteria	N	Portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F,Phage_portal
SX3_k127_3810707_3	402881.Plav_0902	5.894e-08	54.0	COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,1JNNI@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
SX3_k127_3814139_2	204669.Acid345_1348	8.774e-65	241.0	COG3016@1|root,COG3016@2|Bacteria	2|Bacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	phuW	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2
SX3_k127_3814139_0	338963.Pcar_0086	5.793e-120	400.0	COG0168@1|root,COG0168@2|Bacteria,1N412@1224|Proteobacteria,42MBI@68525|delta/epsilon subdivisions,2WIZ9@28221|Deltaproteobacteria,43S5D@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
SX3_k127_3814139_1	1121405.dsmv_1140	2.288e-75	259.0	COG0569@1|root,COG0569@2|Bacteria,1R7KM@1224|Proteobacteria,42PJH@68525|delta/epsilon subdivisions,2WMZT@28221|Deltaproteobacteria,2MJ9H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SX3_k127_3815739_1	1499689.CCNN01000004_gene223	6.173e-58	224.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,2480Q@186801|Clostridia,36FTT@31979|Clostridiaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS11880	GDC-P
SX3_k127_3815739_0	1379698.RBG1_1C00001G1499	1.066e-119	397.0	COG0403@1|root,COG0403@2|Bacteria,2NNP1@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204	1.4.4.2	ko:K00281,ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SX3_k127_382017_1	1265505.ATUG01000001_gene3198	3.728e-09	63.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42Q13@68525|delta/epsilon subdivisions,2WJHD@28221|Deltaproteobacteria,2MJ10@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM dihydropteroate synthase DHPS	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SX3_k127_382017_0	945713.IALB_0376	4.943e-82	290.0	COG1207@1|root,COG1207@2|Bacteria	2|Bacteria	M	glucosamine-1-phosphate N-acetyltransferase activity	glmU	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_4
SX3_k127_3831894_0	882083.SacmaDRAFT_0378	1.111e-27	128.0	COG1807@1|root,COG1807@2|Bacteria,2IEB9@201174|Actinobacteria,4E27D@85010|Pseudonocardiales	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3852594_1	1210884.HG799463_gene9610	4.037e-27	119.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SX3_k127_3852594_0	335543.Sfum_3685	1.092e-52	191.0	299T8@1|root,2ZWVF@2|Bacteria,1N5QA@1224|Proteobacteria,42ZI5@68525|delta/epsilon subdivisions,2WV28@28221|Deltaproteobacteria,2MRN5@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3852594_2	865937.Gilli_3276	2.443e-11	75.0	2CESB@1|root,2Z8UZ@2|Bacteria,4NJSJ@976|Bacteroidetes,1I15D@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
SX3_k127_3859673_0	909663.KI867150_gene485	7.478e-152	490.0	COG1148@1|root,COG1148@2|Bacteria,1N26U@1224|Proteobacteria,43EWE@68525|delta/epsilon subdivisions,2X2B6@28221|Deltaproteobacteria,2MRJK@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SX3_k127_3859673_4	383372.Rcas_3103	0.000227	53.0	COG3307@1|root,COG3307@2|Bacteria,2GB55@200795|Chloroflexi,377AJ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SX3_k127_3859673_1	760568.Desku_1557	2.921e-62	232.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia,261PX@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SX3_k127_3859673_3	1265505.ATUG01000002_gene1027	1.868e-05	49.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,42M7Q@68525|delta/epsilon subdivisions,2WJ9Z@28221|Deltaproteobacteria,2MIK8@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SX3_k127_38628_1	1035189.HMPREF9954_0798	8.275e-27	115.0	COG1445@1|root,COG1762@1|root,COG1445@2|Bacteria,COG1762@2|Bacteria,1UJ3M@1239|Firmicutes,4IT0X@91061|Bacilli	91061|Bacilli	GT	PTS system, Lactose/Cellobiose specific IIB subunit	-	-	2.7.1.202	ko:K02768,ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_IIB
SX3_k127_38628_0	518766.Rmar_1702	1.326e-72	256.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1FIU8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
SX3_k127_3867188_0	1254432.SCE1572_49140	3.595e-143	478.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,42PEY@68525|delta/epsilon subdivisions,2WJJ3@28221|Deltaproteobacteria,2YUIV@29|Myxococcales	28221|Deltaproteobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SX3_k127_3873725_1	1267535.KB906767_gene4240	1.748e-05	50.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Trans_reg_C
SX3_k127_3873725_0	1379698.RBG1_1C00001G1218	2.825e-129	435.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
SX3_k127_3884085_0	760142.Hipma_1076	2.06e-101	343.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2WJ4D@28221|Deltaproteobacteria,2M6A7@213113|Desulfurellales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	yfdZ	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SX3_k127_3884085_1	927704.SELR_27260	5.136e-20	94.0	COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4H54R@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SX3_k127_3884085_2	1122132.AQYH01000018_gene1110	1.351e-09	61.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2U8D6@28211|Alphaproteobacteria,4BMRA@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SX3_k127_3896970_2	880073.Calab_2182	3.35e-07	60.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
SX3_k127_3896970_0	1254432.SCE1572_46680	1.032e-70	258.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42PY9@68525|delta/epsilon subdivisions,2WMGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	coenzyme F390	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
SX3_k127_3896970_1	1234679.BN424_537	2.201e-30	125.0	COG0686@1|root,COG0686@2|Bacteria,1TRCT@1239|Firmicutes,4HB20@91061|Bacilli,27GMC@186828|Carnobacteriaceae	91061|Bacilli	E	Alanine dehydrogenase/PNT, N-terminal domain	ceo	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0047126,GO:0055114	1.5.1.24	ko:K00298	-	-	-	-	ko00000,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SX3_k127_3907797_1	1379698.RBG1_1C00001G1445	1.132e-19	96.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NQSG@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2
SX3_k127_3907797_0	1121335.Clst_2400	1.112e-39	152.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3WGKX@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SX3_k127_3909308_3	358396.C445_18396	4.008e-35	136.0	COG2057@1|root,arCOG05316@2157|Archaea,2XW2C@28890|Euryarchaeota,23U50@183963|Halobacteria	183963|Halobacteria	I	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SX3_k127_3909308_2	224325.AF_1199	4.406e-139	449.0	COG1788@1|root,arCOG01987@2157|Archaea,2XVRA@28890|Euryarchaeota,246WP@183980|Archaeoglobi	183980|Archaeoglobi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SX3_k127_3909308_1	1125863.JAFN01000001_gene170	7.915e-176	559.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acyl-coa dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SX3_k127_3909308_0	387092.NIS_0283	3.607e-197	621.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2YMAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SX3_k127_3915371_0	1379698.RBG1_1C00001G1576	3.898e-147	473.0	COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria	2|Bacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SX3_k127_3915371_1	521045.Kole_1881	2.57e-63	224.0	COG0563@1|root,COG0563@2|Bacteria,2GCW0@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SX3_k127_3915371_2	555079.Toce_0140	3.093e-29	119.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,42F6V@68295|Thermoanaerobacterales	186801|Clostridia	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SX3_k127_3922936_1	504832.OCAR_6238	2.814e-18	85.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,3JTF6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SX3_k127_3922936_0	1157638.KB892166_gene4722	4.882e-90	307.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SX3_k127_3930204_1	671143.DAMO_1448	3.826e-12	78.0	COG2234@1|root,COG2234@2|Bacteria,2NQ2F@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SX3_k127_3930204_0	439235.Dalk_3718	1.593e-36	146.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,2MHTD@213118|Desulfobacterales	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
SX3_k127_3938264_0	591157.SSLG_04784	1.78e-05	55.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SX3_k127_3940128_0	272569.rrnAC3030	0.0006531	51.0	COG0613@1|root,arCOG01312@1|root,arCOG03264@1|root,arCOG00302@2157|Archaea,arCOG01312@2157|Archaea,arCOG03264@2157|Archaea	2157|Archaea	E	metal-dependent phosphoesterases (PHP family)	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,CarboxypepD_reg,DDOST_48kD,PEGA
SX3_k127_3942100_0	1307759.JOMJ01000004_gene2475	9.953e-08	61.0	2BV24@1|root,32QEZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
SX3_k127_3942100_1	313603.FB2170_10111	9.276e-06	56.0	COG3055@1|root,COG3204@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia,2PGXB@252356|Maribacter	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
SX3_k127_3945215_1	945713.IALB_1003	3.19e-23	103.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3945215_0	1047013.AQSP01000075_gene1424	1.744e-145	494.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SX3_k127_3950071_2	1041930.Mtc_1015	7.1e-37	154.0	COG0457@1|root,arCOG03042@1|root,arCOG03032@2157|Archaea,arCOG03042@2157|Archaea,2Y7M7@28890|Euryarchaeota,2NBM0@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
SX3_k127_3950071_5	518766.Rmar_2265	8.539e-05	53.0	2EKPU@1|root,33EDK@2|Bacteria,4P8S4@976|Bacteroidetes,1FJH6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3950071_3	316067.Geob_1006	2.083e-34	136.0	COG0784@1|root,COG0784@2|Bacteria,1N017@1224|Proteobacteria,42UW8@68525|delta/epsilon subdivisions,2X7PA@28221|Deltaproteobacteria,43W1W@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SX3_k127_3950071_0	398767.Glov_3124	1.305e-65	242.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,43T5D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
SX3_k127_3950071_4	525903.Taci_1563	4.2e-11	73.0	COG1560@1|root,COG1560@2|Bacteria,3TAXY@508458|Synergistetes	508458|Synergistetes	M	Lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SX3_k127_3950071_1	667014.Thein_1081	5.767e-45	173.0	COG0438@1|root,COG0438@2|Bacteria,2GI3U@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Glycosyl transferase 4-like domain	-	-	2.4.1.345,2.4.1.348	ko:K08256,ko:K12995	-	-	R11702	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SX3_k127_3961648_0	1122176.KB903587_gene4485	5.359e-82	295.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,4PPP2@976|Bacteroidetes,1IZ5Q@117747|Sphingobacteriia	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3972224_1	1379698.RBG1_1C00001G1742	8.47e-06	58.0	COG2805@1|root,COG2805@2|Bacteria,2NNR7@2323|unclassified Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SX3_k127_3972224_0	639282.DEFDS_1109	9.47e-164	524.0	COG2804@1|root,COG2804@2|Bacteria,2GEP7@200930|Deferribacteres	200930|Deferribacteres	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SX3_k127_399095_0	1519464.HY22_02120	3.882e-13	83.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria,1FERA@1090|Chlorobi	1090|Chlorobi	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_399095_1	1379698.RBG1_1C00001G1786	1.655e-10	72.0	2CUTJ@1|root,32SW3@2|Bacteria,2NRD1@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_399095_3	443144.GM21_3112	8.883e-05	52.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42ZN4@68525|delta/epsilon subdivisions,2WV34@28221|Deltaproteobacteria,43VPK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
SX3_k127_3992329_0	1519464.HY22_01240	6.321e-139	452.0	COG0126@1|root,COG0126@2|Bacteria,1FDBD@1090|Chlorobi	1090|Chlorobi	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SX3_k127_3994256_0	96561.Dole_1704	1.051e-26	123.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_3997178_0	1192034.CAP_3408	1.031e-129	436.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SX3_k127_4002644_1	1123288.SOV_3c03710	3.584e-23	104.0	COG0763@1|root,COG0763@2|Bacteria,1TRP4@1239|Firmicutes,4H22C@909932|Negativicutes	909932|Negativicutes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
SX3_k127_4002644_3	1379698.RBG1_1C00001G1645	5.012e-13	75.0	COG2121@1|root,COG2121@2|Bacteria,2NPP6@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF374)	MA20_05800	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527,ko:K09778	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	DUF374
SX3_k127_4002644_0	1238182.C882_2578	4.409e-27	124.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,2TSGQ@28211|Alphaproteobacteria,2JS37@204441|Rhodospirillales	204441|Rhodospirillales	S	protein conserved in bacteria	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
SX3_k127_4002644_2	177437.HRM2_18110	5.611e-16	86.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2WNJ4@28221|Deltaproteobacteria,2MJ99@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
SX3_k127_4011957_0	1125863.JAFN01000001_gene1761	0.0	1065.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
SX3_k127_4011957_1	667014.Thein_1357	2.847e-53	211.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,2GGV4@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	I	CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
SX3_k127_4021923_0	1121930.AQXG01000001_gene1203	9.542e-266	837.0	COG0841@1|root,COG0841@2|Bacteria,4NGCI@976|Bacteroidetes	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SX3_k127_4021923_1	1121930.AQXG01000001_gene1202	1.147e-152	503.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPZZ@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SX3_k127_4033316_1	545694.TREPR_2598	3.466e-11	71.0	COG0544@1|root,COG0544@2|Bacteria,2J5FS@203691|Spirochaetes	203691|Spirochaetes	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SX3_k127_4033316_0	1158318.ATXC01000001_gene1441	5.523e-72	246.0	COG0740@1|root,COG0740@2|Bacteria,2G3IM@200783|Aquificae	200783|Aquificae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SX3_k127_4049302_0	1379698.RBG1_1C00001G1515	1.097e-21	107.0	COG0457@1|root,COG0457@2|Bacteria	1379698.RBG1_1C00001G1515|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4057377_0	518766.Rmar_1948	1.072e-88	307.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,1FJ19@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Beta-eliminating lyase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SX3_k127_405798_0	269799.Gmet_0412	7.35e-70	255.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,43UB0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SX3_k127_405798_1	335541.Swol_0825	4.702e-24	106.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,42JMA@68298|Syntrophomonadaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SX3_k127_4058443_1	1229172.JQFA01000004_gene1859	1.429e-40	154.0	COG4826@1|root,COG4826@2|Bacteria,1G29E@1117|Cyanobacteria,1H9A9@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
SX3_k127_4058443_0	1121468.AUBR01000001_gene523	7.579e-106	354.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,42F3Z@68295|Thermoanaerobacterales	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SX3_k127_4062162_1	459349.CLOAM1614	8.184e-22	108.0	COG1572@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,2NR5X@2323|unclassified Bacteria	2|Bacteria	Q	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,FlgD_ig,Laminin_G_3
SX3_k127_4062162_0	1150474.JQJI01000023_gene762	1.069e-45	170.0	COG0599@1|root,COG1956@1|root,COG0599@2|Bacteria,COG1956@2|Bacteria,2GCRH@200918|Thermotogae	200918|Thermotogae	T	PFAM GAF domain	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2,GGDEF
SX3_k127_4067572_3	1121396.KB892990_gene4470	2e-39	155.0	COG0697@1|root,COG0697@2|Bacteria,1Q9JX@1224|Proteobacteria,434FQ@68525|delta/epsilon subdivisions,2WYT5@28221|Deltaproteobacteria,2MN71@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SX3_k127_4067572_2	313606.M23134_07555	4.635e-64	235.0	295M7@1|root,2ZSYM@2|Bacteria,4NNH9@976|Bacteroidetes,47UGS@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4067572_0	1121930.AQXG01000001_gene1204	1.212e-95	328.0	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SX3_k127_4067572_1	1121930.AQXG01000001_gene1203	1.702e-91	327.0	COG0841@1|root,COG0841@2|Bacteria,4NGCI@976|Bacteroidetes	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SX3_k127_4074851_1	1047013.AQSP01000113_gene742	5.044e-41	163.0	28V7D@1|root,2ZHAI@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
SX3_k127_4074851_0	1047013.AQSP01000113_gene743	3.518e-136	450.0	COG3225@1|root,COG3225@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
SX3_k127_4100476_0	290318.Cvib_0237	2.5e-55	207.0	COG0438@1|root,COG0438@2|Bacteria,1FE7C@1090|Chlorobi	1090|Chlorobi	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SX3_k127_411626_0	1379698.RBG1_1C00001G0404	3.757e-17	87.0	2EAFJ@1|root,334IY@2|Bacteria,2NRZR@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
SX3_k127_411626_1	1313304.CALK_0880	2.377e-05	55.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K16191	-	-	-	-	ko00000,ko02000	1.B.6.1.3	-	-	OmpA
SX3_k127_4116317_2	867903.ThesuDRAFT_02360	9.597e-21	92.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3WCFP@538999|Clostridiales incertae sedis	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SX3_k127_4116317_0	671143.DAMO_0447	9.4e-58	213.0	COG1694@1|root,COG3956@2|Bacteria,2NP9V@2323|unclassified Bacteria	2|Bacteria	E	MazG nucleotide pyrophosphohydrolase domain	mazG	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66,3.6.1.9	ko:K02428,ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	iJN678.sll1005	MazG,TP_methylase
SX3_k127_4116317_1	502025.Hoch_1947	5.087e-50	183.0	COG2885@1|root,COG2885@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria,2YUE1@29|Myxococcales	1224|Proteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.6	-	-	Cadherin_3,DUF11,DUF4347,OmpA,Phenol_MetA_deg,TSP_3
SX3_k127_4116830_0	880073.Calab_0952	1.885e-56	217.0	COG0706@1|root,COG0706@2|Bacteria,2NP6C@2323|unclassified Bacteria	2|Bacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
SX3_k127_4120691_1	243231.GSU1941	7.111e-42	165.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,42PTN@68525|delta/epsilon subdivisions,2WKBJ@28221|Deltaproteobacteria,43SC3@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c
SX3_k127_4120691_0	1232410.KI421418_gene2418	6.922e-135	445.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Q6R@68525|delta/epsilon subdivisions,2WJN4@28221|Deltaproteobacteria,43TK0@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SX3_k127_4120897_0	365044.Pnap_0406	6.154e-14	82.0	COG1470@1|root,COG1520@1|root,COG3188@1|root,COG1470@2|Bacteria,COG1520@2|Bacteria,COG3188@2|Bacteria,1QV71@1224|Proteobacteria,2VKHC@28216|Betaproteobacteria,4AGE2@80864|Comamonadaceae	28216|Betaproteobacteria	NU	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
SX3_k127_4120897_1	374847.Kcr_0264	3.565e-12	80.0	arCOG02497@1|root,arCOG02497@2157|Archaea	2157|Archaea	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SX3_k127_4124398_1	945713.IALB_3074	1.914e-09	71.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin,Thioredoxin_2,Thioredoxin_9
SX3_k127_4124398_0	1047013.AQSP01000105_gene1461	9.64e-224	719.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria	2|Bacteria	EU	peptidase S9 prolyl oligopeptidase active site	dap2	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
SX3_k127_4127418_0	580340.Tlie_0145	2.191e-159	512.0	COG3844@1|root,COG3844@2|Bacteria,3TA91@508458|Synergistetes	508458|Synergistetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SX3_k127_4127418_1	105425.BBPL01000036_gene4350	5.019e-69	247.0	COG0500@1|root,COG2226@2|Bacteria,2IF5R@201174|Actinobacteria,2NHMA@228398|Streptacidiphilus	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_31
SX3_k127_4127418_3	391623.TERMP_01760	1.984e-07	57.0	arCOG03769@1|root,arCOG03769@2157|Archaea,2Y3V9@28890|Euryarchaeota,245JM@183968|Thermococci	183968|Thermococci	M	glucosylceramidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4127418_2	1198452.Jab_1c18910	4.097e-13	76.0	COG1807@1|root,COG1807@2|Bacteria,1R4F0@1224|Proteobacteria,2VNW5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SX3_k127_413141_1	1254432.SCE1572_18080	4.926e-10	73.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,434QI@68525|delta/epsilon subdivisions,2X8Z6@28221|Deltaproteobacteria,2Z152@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_413141_0	1089548.KI783301_gene2313	3.993e-44	173.0	COG0438@1|root,COG0438@2|Bacteria,1UTQH@1239|Firmicutes,4HBYI@91061|Bacilli,3WFUU@539002|Bacillales incertae sedis	91061|Bacilli	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SX3_k127_4154654_0	1379698.RBG1_1C00001G0608	8.309e-154	501.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
SX3_k127_4155090_0	1121439.dsat_1304	7.942e-08	64.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,42PTN@68525|delta/epsilon subdivisions,2WKBJ@28221|Deltaproteobacteria,2MHD1@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c
SX3_k127_4166293_2	1395513.P343_17790	2.489e-13	71.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,26NR0@186821|Sporolactobacillaceae	91061|Bacilli	K	ECF sigma factor	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SX3_k127_4166293_0	1341151.ASZU01000008_gene1626	9.576e-192	606.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,27B4J@186824|Thermoactinomycetaceae	91061|Bacilli	G	Enolase, N-terminal domain	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SX3_k127_4166293_7	330214.NIDE2912	0.0002688	48.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	ftsB	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
SX3_k127_4166293_5	880073.Calab_2081	2.496e-06	61.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
SX3_k127_4166293_1	861299.J421_5839	1.6e-41	174.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SX3_k127_4166293_6	1379698.RBG1_1C00001G1817	5.152e-06	60.0	COG0308@1|root,COG0308@2|Bacteria,2NRIZ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Cofac_haem_bdg,NAAA-beta,Peptidase_M1,Phospholip_B
SX3_k127_4166293_3	1047013.AQSP01000098_gene2571	1.187e-11	66.0	COG3579@1|root,COG3579@2|Bacteria	2|Bacteria	E	homocysteine catabolic process	-	-	3.4.22.40	ko:K01372,ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03032	-	-	-	Peptidase_C1,Peptidase_C1_2
SX3_k127_4168912_0	314285.KT71_11209	1.339e-75	261.0	2DCFR@1|root,2ZDYQ@2|Bacteria,1RB5X@1224|Proteobacteria,1RN4F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4168912_1	1173028.ANKO01000006_gene2024	1.101e-11	72.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SX3_k127_4170251_1	203275.BFO_2717	1.094e-32	135.0	28KQH@1|root,2ZA8A@2|Bacteria	2|Bacteria	S	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
SX3_k127_4170251_0	471875.RUMLAC_00271	1.504e-36	145.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,3WGR0@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
SX3_k127_4170498_0	945713.IALB_3185	4.064e-218	689.0	COG0458@1|root,COG0458@2|Bacteria	2|Bacteria	F	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SX3_k127_4177093_0	1089550.ATTH01000001_gene1005	1.069e-10	74.0	COG1404@1|root,COG3591@1|root,COG4932@1|root,COG1404@2|Bacteria,COG3591@2|Bacteria,COG4932@2|Bacteria,4NG2K@976|Bacteroidetes,1FJTD@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EO	Trypsin-like serine protease	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Trypsin_2
SX3_k127_4177608_0	1131730.BAVI_05739	4.339e-110	368.0	COG4671@1|root,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C
SX3_k127_4178480_1	1047013.AQSP01000130_gene1866	1.595e-100	330.0	COG0591@1|root,COG0591@2|Bacteria,2NR5Z@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SX3_k127_4178480_0	1313421.JHBV01000003_gene663	2.89e-293	925.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1IQP1@117747|Sphingobacteriia	976|Bacteroidetes	G	Chitobiase/beta-hexosaminidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
SX3_k127_4182307_0	1278073.MYSTI_02092	2.292e-192	631.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WN7A@28221|Deltaproteobacteria,2YTZA@29|Myxococcales	28221|Deltaproteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SX3_k127_4186823_0	1173022.Cri9333_1649	4.219e-09	68.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_2,TPR_8
SX3_k127_4200290_0	443143.GM18_4316	2.324e-38	162.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Big_2,CUB,He_PIG,Peptidase_S8
SX3_k127_4200290_1	743719.PaelaDRAFT_3046	3.989e-05	56.0	COG4733@1|root,COG4733@2|Bacteria,1V0X5@1239|Firmicutes,4HDRK@91061|Bacilli,26VBX@186822|Paenibacillaceae	91061|Bacilli	DZ	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like
SX3_k127_4202190_1	340.xcc-b100_2995	1.495e-33	136.0	COG1595@1|root,COG1595@2|Bacteria,1R7KF@1224|Proteobacteria,1S2IU@1236|Gammaproteobacteria,1XC71@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SX3_k127_4202190_0	1047013.AQSP01000053_gene292	1.996e-59	215.0	COG0793@1|root,COG0793@2|Bacteria,2NQ8W@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SX3_k127_4202858_1	666685.R2APBS1_1311	3.691e-37	142.0	COG1695@1|root,COG1695@2|Bacteria,1NJSY@1224|Proteobacteria,1SG6R@1236|Gammaproteobacteria,1X6UG@135614|Xanthomonadales	135614|Xanthomonadales	K	PadR family transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
SX3_k127_4202858_0	1300345.LF41_2556	4.396e-58	210.0	COG4709@1|root,COG4709@2|Bacteria,1NX5K@1224|Proteobacteria,1SPS6@1236|Gammaproteobacteria,1X34I@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative sensor	-	-	-	-	-	-	-	-	-	-	-	-	Sensor
SX3_k127_420318_0	1269813.ATUL01000014_gene1417	7.99e-127	434.0	COG1215@1|root,COG1215@2|Bacteria,1MWF8@1224|Proteobacteria,1RQ9P@1236|Gammaproteobacteria,1X2BJ@135613|Chromatiales	135613|Chromatiales	M	Cellulose synthase	-	-	-	-	-	-	-	-	-	-	-	-	Cellulose_synt,Glycos_transf_2,PilZ
SX3_k127_420318_1	134676.ACPL_1545	1.703e-24	118.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,4D95T@85008|Micromonosporales	201174|Actinobacteria	GL	Reverse transcriptase-like	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
SX3_k127_420318_2	1501391.LG35_02950	9.923e-17	90.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,2FPGP@200643|Bacteroidia,22U60@171550|Rikenellaceae	976|Bacteroidetes	S	Zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SX3_k127_421368_0	393921.HQ45_08345	4.994e-209	660.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,2FMKD@200643|Bacteroidia,22W4Y@171551|Porphyromonadaceae	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase (glutamine-hydrolyzing)	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,MGS
SX3_k127_421368_1	1211813.CAPH01000009_gene254	3.568e-34	132.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,2FMSR@200643|Bacteroidia,22VRM@171550|Rikenellaceae	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SX3_k127_4221247_1	1444310.JANV01000091_gene4173	0.0001352	52.0	COG2234@1|root,COG2234@2|Bacteria,1UFM1@1239|Firmicutes,4HCR1@91061|Bacilli,1ZR6G@1386|Bacillus	91061|Bacilli	S	Peptidase family M28	ywaD	-	3.4.11.10,3.4.11.6	ko:K19701	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28
SX3_k127_4221247_0	56780.SYN_01924	5.548e-132	429.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,42NRA@68525|delta/epsilon subdivisions,2WJ62@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
SX3_k127_4221887_0	1121405.dsmv_2717	1.235e-53	193.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2MHW3@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SX3_k127_4223539_1	1242864.D187_006890	6.573e-11	68.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,MASE3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SX3_k127_4223539_0	1144343.PMI41_03035	6.162e-15	81.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,2TU8I@28211|Alphaproteobacteria,43PEB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glycos_transf_1
SX3_k127_423259_2	1268237.G114_19166	1.578e-05	52.0	COG1596@1|root,COG1596@2|Bacteria,1PK0J@1224|Proteobacteria,1RM8V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Periplasmic protein involved in polysaccharide export	-	-	-	ko:K20987	ko02025,map02025	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SX3_k127_423259_1	195103.CPF_0464	1.26e-07	64.0	COG3944@1|root,COG3944@2|Bacteria,1V4XU@1239|Firmicutes,25CQW@186801|Clostridia,36WZD@31979|Clostridiaceae	186801|Clostridia	M	PFAM lipopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
SX3_k127_423259_0	880073.Calab_3531	4.295e-35	153.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
SX3_k127_4233349_2	575590.HMPREF0156_01407	1.119e-21	97.0	COG1308@1|root,COG1308@2|Bacteria,4NVAE@976|Bacteroidetes	976|Bacteroidetes	K	Domain of unknown function (DUF4342)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
SX3_k127_4233349_1	1191523.MROS_0247	5.427e-47	172.0	COG3304@1|root,COG3304@2|Bacteria	2|Bacteria	S	Inner membrane component domain	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
SX3_k127_4233349_0	706587.Desti_0912	2.058e-65	229.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42R8Z@68525|delta/epsilon subdivisions,2WMXX@28221|Deltaproteobacteria,2MQMD@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
SX3_k127_4240078_0	240016.ABIZ01000001_gene5365	4.852e-34	139.0	COG1524@1|root,COG1524@2|Bacteria,46XAN@74201|Verrucomicrobia,2IV7D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SX3_k127_4240078_1	313628.LNTAR_11821	6.972e-05	55.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SX3_k127_4258888_2	456320.Mvol_1273	8.267e-14	75.0	COG1146@1|root,arCOG00959@2157|Archaea,2XZY3@28890|Euryarchaeota,23R9B@183939|Methanococci	183939|Methanococci	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
SX3_k127_4258888_0	1125863.JAFN01000001_gene1978	1.124e-125	412.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2WJ97@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
SX3_k127_4258888_1	1125863.JAFN01000001_gene1977	1.229e-41	171.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2WJQ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Thiamine pyrophosphate	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SX3_k127_4264445_0	1379698.RBG1_1C00001G1860	6.36e-48	173.0	COG1077@1|root,COG1077@2|Bacteria,2NNVU@2323|unclassified Bacteria	2|Bacteria	D	MreB/Mbl protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SX3_k127_4264445_1	589865.DaAHT2_1934	1.522e-26	120.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2MJMG@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SX3_k127_4264445_2	335541.Swol_1639	0.0006611	48.0	COG2891@1|root,COG2891@2|Bacteria,1TV3K@1239|Firmicutes,259AA@186801|Clostridia,42KQ1@68298|Syntrophomonadaceae	186801|Clostridia	M	rod shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
SX3_k127_4269488_0	880073.Calab_3649	7.139e-78	283.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2NP1D@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase SLT domain	CP_0155	-	-	ko:K08307,ko:K12204	-	-	-	-	ko00000,ko01000,ko01011,ko02044	3.A.7.10.1,3.A.7.9.1	-	-	LysM,SLT,T4SS_TraI
SX3_k127_4276311_0	246194.CHY_1985	1.185e-136	445.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,42EPX@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SX3_k127_4276311_2	349161.Dred_0645	8.386e-13	76.0	COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,24MV7@186801|Clostridia,26250@186807|Peptococcaceae	186801|Clostridia	S	PFAM Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
SX3_k127_4276311_1	314230.DSM3645_22886	7.506e-51	187.0	COG0142@1|root,COG0142@2|Bacteria,2IX56@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SX3_k127_4277299_1	635013.TherJR_2161	4.425e-58	216.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2619Y@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SX3_k127_4277299_0	1121468.AUBR01000006_gene362	1.473e-102	349.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,42EZQ@68295|Thermoanaerobacterales	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SX3_k127_4286282_0	945713.IALB_2868	6.943e-25	104.0	COG2986@1|root,COG2986@2|Bacteria	2|Bacteria	E	ammonia-lyase activity	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SX3_k127_4286282_3	203275.BFO_2676	2.718e-05	56.0	2FJRB@1|root,34BE7@2|Bacteria,4P5QR@976|Bacteroidetes,2FYTE@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4286282_2	873533.HMPREF0663_10287	1.108e-09	70.0	2FJRB@1|root,34BE7@2|Bacteria,4P5QR@976|Bacteroidetes,2FYTE@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4286282_1	435908.IDSA_01265	2.213e-12	79.0	2EID4@1|root,33C4H@2|Bacteria,1NINC@1224|Proteobacteria,1SGS1@1236|Gammaproteobacteria,2QGK6@267893|Idiomarinaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4288160_2	983545.Glaag_0981	0.0008296	49.0	2DABX@1|root,32TV4@2|Bacteria,1N0Q8@1224|Proteobacteria,1SAC9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4288160_0	118005.AWNK01000006_gene1264	3.868e-71	255.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004,ko:K09808	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.125	-	-	FtsX,MacB_PCD
SX3_k127_4288160_1	653733.Selin_0904	6.709e-55	207.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	macB_2	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
SX3_k127_4291547_0	370438.PTH_2122	4.274e-186	592.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,2602D@186807|Peptococcaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SX3_k127_430023_0	314230.DSM3645_04585	4.114e-66	232.0	COG0149@1|root,COG0149@2|Bacteria,2IXV9@203682|Planctomycetes	203682|Planctomycetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SX3_k127_430023_2	443143.GM18_1890	5.257e-13	75.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SX3_k127_430023_1	1280664.AUIX01000001_gene832	5.231e-13	77.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,4BY01@830|Butyrivibrio	186801|Clostridia	D	Protein of unknown function (DUF4446)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
SX3_k127_4302410_1	751944.HALDL1_02100	2.162e-38	160.0	2DZ6J@1|root,2N585@2157|Archaea,2Y4JQ@28890|Euryarchaeota	28890|Euryarchaeota	S	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SX3_k127_4302410_0	391587.KAOT1_07263	7.191e-139	449.0	2C57D@1|root,2Z7RS@2|Bacteria,4NEKN@976|Bacteroidetes,1HXT2@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
SX3_k127_4303733_0	880073.Calab_2079	1.848e-52	192.0	COG1668@1|root,COG1668@2|Bacteria,2NPCQ@2323|unclassified Bacteria	2|Bacteria	CP	ABC-2 family transporter protein	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SX3_k127_4307634_1	891968.Anamo_1584	2.26e-35	141.0	COG0438@1|root,COG0438@2|Bacteria,3TAFG@508458|Synergistetes	508458|Synergistetes	H	PFAM glycosyl transferase group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
SX3_k127_4307634_0	247490.KSU1_D0579	5.972e-72	249.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gtf2	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4307634_2	690850.Desaf_0530	7.235e-09	59.0	COG1554@1|root,COG1877@1|root,COG1554@2|Bacteria,COG1877@2|Bacteria,1MWJE@1224|Proteobacteria,42Q4Z@68525|delta/epsilon subdivisions,2WM28@28221|Deltaproteobacteria,2M9SQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Glycoside hydrolase family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Hydrolase
SX3_k127_4309940_0	335543.Sfum_1996	6.34e-61	219.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2MQCK@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
SX3_k127_4309940_1	880072.Desac_1148	5.73e-57	224.0	COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,43C2J@68525|delta/epsilon subdivisions,2X7D5@28221|Deltaproteobacteria,2MQEP@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SX3_k127_4309940_2	497964.CfE428DRAFT_0347	4.512e-24	110.0	2E5IJ@1|root,3309Y@2|Bacteria,46SYV@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4309940_3	521719.ATXQ01000002_gene2457	2.198e-15	79.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1YEWY@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iY75_1357.Y75_RS13445,iYL1228.KPN_02899	FAD_binding_2,Succ_DH_flav_C
SX3_k127_4310347_5	886293.Sinac_1549	1.028e-36	151.0	COG0585@1|root,COG0585@2|Bacteria,2IWTM@203682|Planctomycetes	203682|Planctomycetes	J	PFAM tRNA pseudouridine synthase D TruD	-	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
SX3_k127_4310347_2	891968.Anamo_1886	1.728e-63	242.0	COG1807@1|root,COG1807@2|Bacteria,3TAR6@508458|Synergistetes	508458|Synergistetes	M	PFAM glycosyl transferase family 39	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	PMT_2
SX3_k127_4310347_8	1415756.JQMY01000001_gene369	9.593e-28	115.0	COG3952@1|root,COG3952@2|Bacteria,1MZ60@1224|Proteobacteria,2UCCY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Lipid A Biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
SX3_k127_4310347_1	1125863.JAFN01000001_gene685	1.867e-70	245.0	COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,43BKJ@68525|delta/epsilon subdivisions,2WIZJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SX3_k127_4310347_3	1304885.AUEY01000001_gene3203	9.283e-58	209.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
SX3_k127_4310347_6	1304885.AUEY01000001_gene3204	4.536e-29	123.0	2DPAK@1|root,33193@2|Bacteria,1NDU6@1224|Proteobacteria,432ZD@68525|delta/epsilon subdivisions,2WYIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4310347_7	525897.Dbac_1903	1.56e-28	115.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,42V0C@68525|delta/epsilon subdivisions,2WRJR@28221|Deltaproteobacteria,2MD57@213115|Desulfovibrionales	28221|Deltaproteobacteria	CO	TIGRFAM redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
SX3_k127_4310347_0	1499967.BAYZ01000050_gene2840	1.186e-191	606.0	COG0701@1|root,COG0701@2|Bacteria,2NP6A@2323|unclassified Bacteria	2|Bacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
SX3_k127_4310347_4	1499967.BAYZ01000050_gene2839	2.838e-38	146.0	COG0640@1|root,COG0640@2|Bacteria,2NQ13@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	3.6.4.12	ko:K03655,ko:K03892	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	HTH_20,HTH_5
SX3_k127_4310347_9	1457250.BBMO01000002_gene2316	8.386e-14	85.0	arCOG00373@1|root,arCOG00373@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_43150_0	42256.RradSPS_0124	3.856e-91	306.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CQF1@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SX3_k127_43150_1	1047013.AQSP01000139_gene2393	5.866e-61	216.0	COG1704@1|root,COG1704@2|Bacteria,2NPIW@2323|unclassified Bacteria	2|Bacteria	S	LemA family	lemA2	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SX3_k127_43150_2	562970.Btus_3146	3.266e-12	78.0	COG4625@1|root,COG5492@1|root,COG4625@2|Bacteria,COG5492@2|Bacteria,1V72Z@1239|Firmicutes	1239|Firmicutes	N	PFAM S-layer domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,SLH
SX3_k127_4315100_1	269799.Gmet_3548	1.407e-29	129.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,43T4C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SX3_k127_4315100_3	768710.DesyoDRAFT_2542	5.423e-16	92.0	COG0760@1|root,COG0760@2|Bacteria,1V5Q2@1239|Firmicutes,248JQ@186801|Clostridia,2675Q@186807|Peptococcaceae	186801|Clostridia	O	Peptidylprolyl isomerase	prsA2	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
SX3_k127_4315100_2	909663.KI867150_gene890	2.486e-17	96.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,2MRZD@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SX3_k127_4315100_0	1121468.AUBR01000069_gene1116	8.27e-224	719.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,42EQJ@68295|Thermoanaerobacterales	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SX3_k127_4316816_0	999141.GME_12654	3.46e-89	302.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1XIJT@135619|Oceanospirillales	135619|Oceanospirillales	M	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SX3_k127_4316816_1	443143.GM18_0409	1.158e-09	68.0	COG1572@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.78	ko:K01218,ko:K13276	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH26	-	CARDB,CHB_HEX_C_1,F5_F8_type_C,Laminin_G_3
SX3_k127_4319242_0	1047013.AQSP01000126_gene2741	3.545e-239	751.0	COG0339@1|root,COG0339@2|Bacteria,2NP9Q@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M3	prlC	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SX3_k127_4319242_1	926569.ANT_31340	2.053e-31	128.0	COG0724@1|root,COG0724@2|Bacteria,2G74A@200795|Chloroflexi	200795|Chloroflexi	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SX3_k127_4319283_0	572546.Arcpr_0668	7.616e-103	344.0	COG0477@1|root,arCOG00143@2157|Archaea,2XUTR@28890|Euryarchaeota,245RD@183980|Archaeoglobi	183980|Archaeoglobi	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SX3_k127_4323966_0	1330700.JQNC01000003_gene722	1.275e-106	375.0	COG1470@1|root,COG4719@1|root,COG1470@2|Bacteria,COG4719@2|Bacteria,1WJNZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
SX3_k127_4323966_1	794903.OPIT5_20790	1.379e-20	108.0	COG3188@1|root,COG3188@2|Bacteria	2|Bacteria	NU	fimbrial usher porin activity	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,DUF11,Plug,SdrD_B,TonB_dep_Rec
SX3_k127_4323966_2	1304883.KI912532_gene162	9.467e-17	96.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,2VKC4@28216|Betaproteobacteria,2KV6P@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar motor protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
SX3_k127_4356658_2	1082932.ATCR1_16111	1.409e-21	98.0	COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,2TSPN@28211|Alphaproteobacteria,4BH5H@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SX3_k127_4356658_1	867845.KI911784_gene762	1.426e-66	241.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SX3_k127_4356658_0	1237149.C900_01702	5.517e-80	282.0	COG0728@1|root,COG0728@2|Bacteria,4NFVD@976|Bacteroidetes,47WHA@768503|Cytophagia	976|Bacteroidetes	U	MviN-like protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SX3_k127_4367388_0	767817.Desgi_0338	3.719e-140	457.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,2609V@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SX3_k127_4367388_1	867903.ThesuDRAFT_00766	1.586e-101	341.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,248D0@186801|Clostridia	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
SX3_k127_4367388_2	1379698.RBG1_1C00001G0842	4.89e-63	226.0	COG1181@1|root,COG1181@2|Bacteria,2NPB2@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SX3_k127_4379763_0	604354.TSIB_0718	2.787e-117	387.0	COG0477@1|root,arCOG00143@2157|Archaea,2Y8EH@28890|Euryarchaeota,245MX@183968|Thermococci	183968|Thermococci	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SX3_k127_4386611_2	459349.CLOAM0985	1.58e-15	89.0	COG1361@1|root,COG1361@2|Bacteria,2NQI0@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
SX3_k127_4386611_0	933262.AXAM01000035_gene2154	4.097e-47	184.0	2E0M7@1|root,32W6F@2|Bacteria,1NB9Z@1224|Proteobacteria,42W6T@68525|delta/epsilon subdivisions,2WSFF@28221|Deltaproteobacteria,2MNT8@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4386611_1	344747.PM8797T_13797	3.682e-22	107.0	2F4XF@1|root,33XJG@2|Bacteria,2J2ZQ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4388684_1	926550.CLDAP_27470	1.676e-42	162.0	COG1228@1|root,COG1228@2|Bacteria,2G5KM@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM amidohydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SX3_k127_4388684_0	292459.STH3193	9.519e-258	805.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia	186801|Clostridia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SX3_k127_4388684_2	1500890.JQNL01000001_gene1082	1.273e-35	141.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1X3ZE@135614|Xanthomonadales	135614|Xanthomonadales	KL	Helicase	yoaA	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2,ResIII
SX3_k127_4400498_0	436114.SYO3AOP1_0232	1.275e-61	226.0	COG2265@1|root,COG2265@2|Bacteria,2G3V7@200783|Aquificae	200783|Aquificae	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
SX3_k127_4400498_1	177437.HRM2_47060	1.604e-56	210.0	COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,42N1Q@68525|delta/epsilon subdivisions,2WJJS@28221|Deltaproteobacteria,2MJ72@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
SX3_k127_4401017_1	1047013.AQSP01000140_gene2549	1.573e-88	296.0	COG1067@1|root,COG1067@2|Bacteria,2NP29@2323|unclassified Bacteria	2|Bacteria	O	peptidase S16	ycbZ	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
SX3_k127_4401017_0	243274.THEMA_00155	2.629e-94	320.0	COG1085@1|root,COG1085@2|Bacteria,2GCAX@200918|Thermotogae	200918|Thermotogae	C	galactose-1-phosphate uridylyltransferase	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0896	GalP_UDP_tr_C,GalP_UDP_transf
SX3_k127_4419705_0	1121468.AUBR01000045_gene1791	2.585e-128	430.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,42FGT@68295|Thermoanaerobacterales	186801|Clostridia	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
SX3_k127_4419705_1	1313304.CALK_0870	8.858e-33	128.0	COG0733@1|root,COG0733@2|Bacteria	2|Bacteria	S	neurotransmitter:sodium symporter activity	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
SX3_k127_4419945_1	1191523.MROS_2755	1.978e-121	397.0	COG0160@1|root,COG0160@2|Bacteria	2|Bacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lat	-	2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36	ko:K00821,ko:K03918,ko:K07250,ko:K13524	ko00220,ko00250,ko00280,ko00300,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,ko04727,map00220,map00250,map00280,map00300,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01210,map01230,map04727	M00016,M00027,M00028,M00845	R00457,R00908,R01648,R02283,R04188,R04475	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iNJ661.Rv3290c	Aminotran_3
SX3_k127_4419945_2	1125863.JAFN01000001_gene2755	5.189e-18	87.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,42V24@68525|delta/epsilon subdivisions,2WR87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SX3_k127_4419945_0	1379698.RBG1_1C00001G1092	7.921e-131	448.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	F5_F8_type_C,Peptidase_M14,Peptidase_M6,Ricin_B_lectin,fn3
SX3_k127_4419945_3	1191523.MROS_0087	0.0002098	55.0	COG1649@1|root,COG3250@1|root,COG3401@1|root,COG4733@1|root,COG1649@2|Bacteria,COG3250@2|Bacteria,COG3401@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	yesX	-	3.2.1.11,3.2.1.18,3.2.1.35,3.2.1.51,4.2.2.23,4.2.2.24	ko:K01186,ko:K01197,ko:K01206,ko:K05988,ko:K11931,ko:K18197,ko:K18198	ko00500,ko00511,ko00531,ko00600,ko01100,ko02026,ko04142,map00500,map00511,map00531,map00600,map01100,map02026,map04142	M00076,M00077	R04018,R07824,R07825,R10905,R11309	RC00028,RC00077	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042,ko04147	-	GH29,GH33,GH66,PL11	-	GHL10,fn3
SX3_k127_4422092_0	1009370.ALO_14392	4.797e-23	114.0	COG0860@1|root,COG0860@2|Bacteria,1TR6H@1239|Firmicutes,4H3UN@909932|Negativicutes	909932|Negativicutes	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
SX3_k127_4426978_1	1125863.JAFN01000001_gene381	1.893e-33	134.0	COG2199@1|root,COG3706@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP
SX3_k127_4426978_0	880073.Calab_2000	2.382e-106	359.0	COG0451@1|root,COG0451@2|Bacteria,2NNNX@2323|unclassified Bacteria	2|Bacteria	GM	NAD(P)H-binding	wbpP	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SX3_k127_4426978_2	1278307.KB906977_gene1645	6.513e-13	76.0	COG1596@1|root,COG1596@2|Bacteria,1PK0J@1224|Proteobacteria,1RM8V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Periplasmic protein involved in polysaccharide export	-	-	-	ko:K20987	ko02025,map02025	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SX3_k127_445299_1	1379698.RBG1_1C00001G1605	7.467e-239	751.0	COG0085@1|root,COG0085@2|Bacteria,2NNM9@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SX3_k127_445299_0	1379698.RBG1_1C00001G1604	0.0	1607.0	COG0086@1|root,COG0086@2|Bacteria,2NNPR@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SX3_k127_4457819_0	1379698.RBG1_1C00001G0608	5.394e-141	476.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
SX3_k127_4461062_2	1536772.R70723_27120	2.919e-49	185.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,26QDR@186822|Paenibacillaceae	91061|Bacilli	P	ATP synthase subunit J	ktrB3	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
SX3_k127_4461062_1	926569.ANT_09260	7.628e-72	263.0	COG0745@1|root,COG0745@2|Bacteria,2G6JP@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SX3_k127_4461062_0	398767.Glov_3227	4.092e-96	328.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42NZF@68525|delta/epsilon subdivisions,2WJNR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
SX3_k127_4463962_1	935845.JADQ01000008_gene1835	6.517e-23	108.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,26X19@186822|Paenibacillaceae	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SX3_k127_4463962_0	1379698.RBG1_1C00001G1489	2.858e-219	689.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SX3_k127_4470841_0	485913.Krac_7650	6.279e-57	203.0	COG0231@1|root,COG0231@2|Bacteria,2G6P4@200795|Chloroflexi	200795|Chloroflexi	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SX3_k127_4470841_1	459349.CLOAM1648	7.607e-31	132.0	COG0457@1|root,COG0457@2|Bacteria	459349.CLOAM1648|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_447284_1	880072.Desac_2166	3.822e-79	271.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2WIIT@28221|Deltaproteobacteria,2MRG4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N,Transketolase_C
SX3_k127_447284_0	880072.Desac_2167	8.262e-120	391.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MRV@68525|delta/epsilon subdivisions,2WK9C@28221|Deltaproteobacteria,2MR5B@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	porB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SX3_k127_4479553_1	880073.Calab_3174	1.389e-10	73.0	2ET5I@1|root,33KPK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
SX3_k127_4479553_0	1121920.AUAU01000004_gene589	3.761e-53	193.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SX3_k127_448458_0	429009.Adeg_0672	7.759e-101	345.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,42F61@68295|Thermoanaerobacterales	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1,4.3.1.29	ko:K01042,ko:K17468	ko00030,ko00450,ko00970,ko01120,map00030,map00450,map00970,map01120	-	R08219,R10408	RC00544,RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SX3_k127_448458_1	596152.DesU5LDRAFT_3347	9.794e-05	52.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WK9E@28221|Deltaproteobacteria,2M8NV@213115|Desulfovibrionales	28221|Deltaproteobacteria	DM	PFAM lipopolysaccharide biosynthesis protein	wzc2	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
SX3_k127_4488713_1	247490.KSU1_D0861	5.549e-78	274.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SX3_k127_4488713_0	1379698.RBG1_1C00001G0712	1.519e-97	335.0	COG0612@1|root,COG0612@2|Bacteria,2NQPM@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SX3_k127_4505279_0	935837.JAEK01000006_gene4282	5.899e-09	65.0	COG0679@1|root,COG0679@2|Bacteria,1UEYG@1239|Firmicutes,4HD45@91061|Bacilli,1ZD15@1386|Bacillus	91061|Bacilli	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
SX3_k127_450706_0	1121468.AUBR01000005_gene8	2.185e-65	232.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,24DII@186801|Clostridia,42G12@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SX3_k127_4521304_1	867903.ThesuDRAFT_01898	2.869e-77	263.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,3WCU3@538999|Clostridiales incertae sedis	186801|Clostridia	E	Amino acid amide ABC transporter ATP-binding protein 1, HAAT family	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SX3_k127_4521304_0	497964.CfE428DRAFT_6600	2.583e-88	299.0	COG0410@1|root,COG0410@2|Bacteria,46SJB@74201|Verrucomicrobia	74201|Verrucomicrobia	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SX3_k127_4521304_2	926567.TheveDRAFT_1236	2.009e-23	104.0	COG2859@1|root,COG2859@2|Bacteria,3TB3A@508458|Synergistetes	508458|Synergistetes	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
SX3_k127_4523380_1	1304888.ATWF01000001_gene896	4.1e-23	105.0	COG0491@1|root,COG0491@2|Bacteria,2GFKR@200930|Deferribacteres	200930|Deferribacteres	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SX3_k127_4523380_2	871968.DESME_07455	7.324e-07	60.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	fixB	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4,Fer4_6,Fer4_7
SX3_k127_4523380_0	192952.MM_2499	1.777e-64	242.0	COG0644@1|root,arCOG00570@2157|Archaea,2XU3J@28890|Euryarchaeota,2N99C@224756|Methanomicrobia	224756|Methanomicrobia	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	bchP	-	1.3.1.101,1.3.7.11	ko:K17830	ko00564,map00564	-	R10325,R10326,R10331	RC03134	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,FAD_binding_3
SX3_k127_4527298_0	880073.Calab_0869	4.844e-88	299.0	COG1180@1|root,COG1180@2|Bacteria,2NNMV@2323|unclassified Bacteria	2|Bacteria	O	Elongator protein 3, MiaB family, Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SX3_k127_4528368_2	926692.AZYG01000019_gene206	1.836e-32	133.0	COG2870@1|root,COG2870@2|Bacteria,1TSMF@1239|Firmicutes,24FJA@186801|Clostridia,3WA7M@53433|Halanaerobiales	186801|Clostridia	M	TIGRFAM rfaE bifunctional protein, domain I	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
SX3_k127_4528368_0	1232410.KI421414_gene2850	3.575e-50	192.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria,43S6D@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SX3_k127_4528368_1	926561.KB900617_gene2134	3.029e-42	156.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WA9Z@53433|Halanaerobiales	186801|Clostridia	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SX3_k127_4530487_0	96561.Dole_1787	4.296e-20	102.0	COG1653@1|root,COG3210@1|root,COG3266@1|root,COG5492@1|root,COG1653@2|Bacteria,COG3210@2|Bacteria,COG3266@2|Bacteria,COG5492@2|Bacteria,1N4S6@1224|Proteobacteria,43BRE@68525|delta/epsilon subdivisions,2X729@28221|Deltaproteobacteria,2MNRP@213118|Desulfobacterales	1224|Proteobacteria	G	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4534763_0	880073.Calab_1134	8.962e-162	526.0	COG2091@1|root,COG2091@2|Bacteria,2NQGR@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SX3_k127_4542659_1	55529.EKX41692	3.13e-07	55.0	28K3T@1|root,2QSIA@2759|Eukaryota	2759|Eukaryota	S	Protein of unknown function (DUF2723)	TMEM260	-	-	-	-	-	-	-	-	-	-	-	DUF2723
SX3_k127_4542659_0	357808.RoseRS_4085	2.232e-80	275.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SX3_k127_454385_0	1347342.BN863_27790	2.464e-09	68.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1HYJD@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
SX3_k127_454385_1	273068.TTE0217	0.0005362	51.0	COG2377@1|root,COG2377@2|Bacteria,1TSBU@1239|Firmicutes,247S1@186801|Clostridia,42HVC@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
SX3_k127_4549216_0	1340493.JNIF01000004_gene448	1.719e-63	229.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3IB@57723|Acidobacteria	57723|Acidobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SX3_k127_4549216_1	1379698.RBG1_1C00001G0632	1.844e-18	89.0	COG1366@1|root,COG1366@2|Bacteria,2NRCS@2323|unclassified Bacteria	2|Bacteria	T	STAS domain	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SX3_k127_4556387_0	1196323.ALKF01000205_gene4274	7.665e-138	446.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,26RXS@186822|Paenibacillaceae	91061|Bacilli	S	Endoribonuclease that initiates mRNA decay	rny	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SX3_k127_4556387_2	1379698.RBG1_1C00001G1123	7.213e-17	83.0	COG1418@1|root,COG1418@2|Bacteria,2NNU5@2323|unclassified Bacteria	2|Bacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SX3_k127_4556387_1	1379698.RBG1_1C00001G1122	4.328e-17	85.0	COG3027@1|root,COG3027@2|Bacteria,2NQ5R@2323|unclassified Bacteria	2|Bacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
SX3_k127_4564627_0	641524.ADICYQ_1984	3.248e-05	55.0	COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,47KV2@768503|Cytophagia	976|Bacteroidetes	M	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
SX3_k127_456575_1	552811.Dehly_0144	1.007e-45	169.0	COG0537@1|root,COG0537@2|Bacteria,2G6SB@200795|Chloroflexi,34CKQ@301297|Dehalococcoidia	301297|Dehalococcoidia	FG	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SX3_k127_456575_4	1191523.MROS_2301	2.025e-08	62.0	COG1316@1|root,COG1316@2|Bacteria	2|Bacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SX3_k127_456575_3	1313301.AUGC01000006_gene169	2.486e-11	66.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SX3_k127_456575_0	1379698.RBG1_1C00001G0456	1.537e-75	276.0	COG0760@1|root,COG0760@2|Bacteria,2NP7B@2323|unclassified Bacteria	2|Bacteria	O	Peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_2,SurA_N_3
SX3_k127_456575_2	908612.HMPREF9720_1654	6.215e-23	103.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,2FP3N@200643|Bacteroidia,22U47@171550|Rikenellaceae	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SX3_k127_4569513_0	1379698.RBG1_1C00001G0719	4.762e-72	250.0	COG0612@1|root,COG0612@2|Bacteria,2NP50@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SX3_k127_4569513_1	1278073.MYSTI_04224	2.807e-57	205.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WK9P@28221|Deltaproteobacteria,2YU0X@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SX3_k127_4569513_2	1125863.JAFN01000001_gene1760	1.672e-44	167.0	COG3581@1|root,COG3581@2|Bacteria,1PDHS@1224|Proteobacteria,43DP1@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
SX3_k127_458111_0	429009.Adeg_1744	1.05e-87	301.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,42GGT@68295|Thermoanaerobacterales	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SX3_k127_4592814_0	1379698.RBG1_1C00001G0518	3.318e-114	394.0	COG0515@1|root,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
SX3_k127_461786_0	1379698.RBG1_1C00001G0607	9.414e-142	466.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
SX3_k127_4619067_0	1408422.JHYF01000006_gene1212	1.034e-99	342.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,36DCX@31979|Clostridiaceae	186801|Clostridia	P	Phosphate transport system permease protein PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
SX3_k127_4619067_1	498761.HM1_2083	1.282e-62	220.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SX3_k127_4619518_1	525904.Tter_1818	2.92e-27	117.0	28I4Y@1|root,2Z88D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4619518_0	555088.DealDRAFT_0494	1.089e-98	338.0	COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,24DU3@186801|Clostridia	186801|Clostridia	P	TIGRFAM anion transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
SX3_k127_4625318_0	880073.Calab_1385	2.599e-65	241.0	COG1807@1|root,COG1807@2|Bacteria,2NP0P@2323|unclassified Bacteria	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT,PMT_2,TPR_19
SX3_k127_4631215_0	1121472.AQWN01000015_gene1350	9.34e-122	400.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,26070@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SX3_k127_4631215_1	110662.Syncc9605_0890	3.626e-52	189.0	COG0245@1|root,COG0336@1|root,COG0245@2|Bacteria,COG0336@2|Bacteria,1G0C1@1117|Cyanobacteria,1GZ5Q@1129|Synechococcus	1117|Cyanobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228,4.6.1.12	ko:K00554,ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R00597,R05637	RC00002,RC00003,RC00334,RC01440	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	YgbB,tRNA_m1G_MT
SX3_k127_4633958_0	459349.CLOAM1790	2.955e-23	113.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
SX3_k127_4635455_0	1379698.RBG1_1C00001G1445	4.028e-111	384.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NQSG@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2
SX3_k127_4652525_1	1397528.Q671_15360	9.235e-12	74.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1XHV8@135619|Oceanospirillales	135619|Oceanospirillales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SX3_k127_4652525_0	391937.NA2_06542	5.185e-23	109.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2TQXJ@28211|Alphaproteobacteria,43H55@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SX3_k127_4656277_0	648996.Theam_0269	1.682e-61	214.0	COG0094@1|root,COG0094@2|Bacteria,2G3N4@200783|Aquificae	200783|Aquificae	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SX3_k127_4656277_2	338963.Pcar_0712	6.359e-31	125.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,42TGC@68525|delta/epsilon subdivisions,2WQ2G@28221|Deltaproteobacteria,43VB6@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal proteins 50S L24/mitochondrial 39S L24	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SX3_k127_4656277_1	1121104.AQXH01000010_gene2437	2.735e-53	189.0	COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,1ISEA@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SX3_k127_4656277_3	1379698.RBG1_1C00001G1587	1.585e-25	107.0	COG0186@1|root,COG0186@2|Bacteria,2NPVE@2323|unclassified Bacteria	2|Bacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SX3_k127_4659143_1	555088.DealDRAFT_1047	3.428e-05	49.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,42JZD@68298|Syntrophomonadaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
SX3_k127_4659143_0	390874.Tpet_1383	3.375e-52	202.0	COG0075@1|root,COG0075@2|Bacteria,2GCGI@200918|Thermotogae	200918|Thermotogae	E	PFAM aminotransferase class V	-	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SX3_k127_4662229_0	1047013.AQSP01000105_gene1443	3.275e-133	429.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SX3_k127_4662229_1	459349.CLOAM0061	6.447e-23	112.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	wprA	-	3.1.3.6,3.1.4.16,3.2.1.99	ko:K01119,ko:K06113,ko:K12685,ko:K20276	ko00230,ko00240,ko02024,map00230,map00240,map02024	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	GH43	-	Mucin_bdg,Peptidase_M60,Peptidase_S8,SLH
SX3_k127_4684891_1	1379698.RBG1_1C00001G0172	4.194e-38	154.0	COG1825@1|root,COG1825@2|Bacteria,2NPVU@2323|unclassified Bacteria	2|Bacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SX3_k127_4684891_0	671143.DAMO_0507	1.375e-105	359.0	COG0462@1|root,COG0462@2|Bacteria,2NNP6@2323|unclassified Bacteria	2|Bacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
SX3_k127_4684891_2	944481.JAFP01000001_gene1200	4.278e-25	107.0	COG2088@1|root,COG2088@2|Bacteria,1N14Y@1224|Proteobacteria,42TGF@68525|delta/epsilon subdivisions,2WQYK@28221|Deltaproteobacteria,2M7C1@213113|Desulfurellales	28221|Deltaproteobacteria	M	SpoVG	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
SX3_k127_4684891_3	243231.GSU0660	6.005e-25	111.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,43TCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SX3_k127_4688253_0	555079.Toce_1642	6.826e-105	347.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,42F4D@68295|Thermoanaerobacterales	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
SX3_k127_4690046_0	1414720.CBYM010000026_gene2427	2.571e-13	79.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,36HEA@31979|Clostridiaceae	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Big_2,CW_binding_2,Cu_amine_oxidN1,SH3_3
SX3_k127_4704209_2	1177181.T9A_02434	1.684e-33	142.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1XJI5@135619|Oceanospirillales	135619|Oceanospirillales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SX3_k127_4704209_1	1141662.OOA_06556	4.616e-40	155.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,3Z7T0@586|Providencia	1236|Gammaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SX3_k127_4704209_0	665571.STHERM_c11330	9.146e-71	246.0	COG0217@1|root,COG0217@2|Bacteria,2J634@203691|Spirochaetes	203691|Spirochaetes	K	Transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SX3_k127_4719541_2	589865.DaAHT2_0700	4.671e-25	108.0	COG0348@1|root,COG1143@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2MPI2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
SX3_k127_4719541_0	56780.SYN_02059	4.004e-75	264.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2MQHV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SX3_k127_4719541_1	1191523.MROS_0927	8.515e-53	197.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	-
SX3_k127_4732487_0	945713.IALB_2583	4.346e-50	195.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SX3_k127_4748122_1	471854.Dfer_0465	1.171e-14	79.0	COG0153@1|root,COG0153@2|Bacteria,4NFSD@976|Bacteroidetes,47K00@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the GHMP kinase family	-	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SX3_k127_4748122_0	493475.GARC_5358	6.657e-188	612.0	COG3345@1|root,COG3345@2|Bacteria,1MW78@1224|Proteobacteria,1RRKC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	enterotoxin	ast	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4750683_1	671143.DAMO_1836	9.174e-33	136.0	COG0860@1|root,COG0860@2|Bacteria,2NPCZ@2323|unclassified Bacteria	2|Bacteria	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
SX3_k127_4750683_2	644966.Tmar_0613	8.455e-18	94.0	COG5401@1|root,COG5401@2|Bacteria,1V64H@1239|Firmicutes	1239|Firmicutes	S	PFAM Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
SX3_k127_4750683_0	1123371.ATXH01000001_gene1294	6.82e-41	156.0	COG0127@1|root,COG0127@2|Bacteria,2GHIS@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SX3_k127_4762992_0	880073.Calab_0681	4.932e-128	449.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,2NP51@2323|unclassified Bacteria	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	pkn5	-	2.7.11.1,3.1.3.3	ko:K04757,ko:K07315	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	AAA_16,GAF,HAMP,HATPase_c_2,Pkinase,SpoIIE,dCache_1
SX3_k127_4762992_3	880073.Calab_2295	3.49e-14	87.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	spoIIAA	-	-	ko:K02066,ko:K04749	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000,ko03021	3.A.1.27	-	-	APH,STAS,STAS_2
SX3_k127_4762992_2	880073.Calab_0680	6.779e-18	100.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SX3_k127_4762992_1	502025.Hoch_4669	2.383e-43	167.0	COG1192@1|root,COG1192@2|Bacteria,1QW1T@1224|Proteobacteria,43BRW@68525|delta/epsilon subdivisions,2X72Q@28221|Deltaproteobacteria,2YZTD@29|Myxococcales	28221|Deltaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SX3_k127_4794501_0	1173027.Mic7113_0883	4.85e-98	331.0	COG3292@1|root,COG3829@1|root,COG3920@1|root,COG3292@2|Bacteria,COG3829@2|Bacteria,COG3920@2|Bacteria,1GCAC@1117|Cyanobacteria,1HEG6@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
SX3_k127_4799211_0	756499.Desde_0733	9.547e-27	120.0	COG2339@1|root,COG2339@2|Bacteria,1V3JI@1239|Firmicutes,24AZQ@186801|Clostridia,266DG@186807|Peptococcaceae	186801|Clostridia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SX3_k127_4812247_1	518766.Rmar_0241	0.0001764	46.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1FJ3Y@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
SX3_k127_4812247_0	880073.Calab_2504	8.599e-66	238.0	COG0795@1|root,COG0795@2|Bacteria,2NPHN@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
SX3_k127_4814588_0	1122919.KB905628_gene31	1.589e-26	127.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,26RDT@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	vicK	-	2.7.13.3	ko:K07652	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9
SX3_k127_4819192_1	290397.Adeh_2421	6.457e-08	64.0	COG0457@1|root,COG0457@2|Bacteria	290397.Adeh_2421|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4819192_0	237368.SCABRO_02636	4.214e-56	210.0	COG1912@1|root,COG1912@2|Bacteria,2IZNZ@203682|Planctomycetes	203682|Planctomycetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SX3_k127_4821730_1	868131.MSWAN_0884	3.946e-30	132.0	COG3359@1|root,arCOG03130@2157|Archaea,2Y790@28890|Euryarchaeota,23PGT@183925|Methanobacteria	183925|Methanobacteria	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
SX3_k127_4821730_0	518766.Rmar_1597	3.318e-67	243.0	COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,1FIM9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SX3_k127_4824940_0	1047013.AQSP01000053_gene292	1.09e-31	135.0	COG0793@1|root,COG0793@2|Bacteria,2NQ8W@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SX3_k127_4829132_3	945713.IALB_0238	5.943e-43	158.0	COG4274@1|root,COG4274@2|Bacteria	2|Bacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SX3_k127_4829132_2	401053.AciPR4_3549	1.949e-53	197.0	COG3279@1|root,COG3279@2|Bacteria,3Y3HR@57723|Acidobacteria,2JIXA@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component transcriptional regulator, LytTR family	-	-	-	ko:K02477,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
SX3_k127_4829132_1	234267.Acid_2181	2.604e-91	316.0	COG2972@1|root,COG2972@2|Bacteria,3Y3NH@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase internal region	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,His_kinase
SX3_k127_4829132_5	273068.TTE2627	1.923e-27	126.0	2CA4A@1|root,32RQK@2|Bacteria,1VE2U@1239|Firmicutes,24QHD@186801|Clostridia,42GU9@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF4416)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4416
SX3_k127_4829132_4	1499967.BAYZ01000185_gene4532	1.241e-30	132.0	COG2162@1|root,COG2162@2|Bacteria	2|Bacteria	Q	arylamine N-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_2
SX3_k127_4829132_0	1121015.N789_06345	1.616e-149	502.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,1X4WG@135614|Xanthomonadales	135614|Xanthomonadales	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SX3_k127_4859853_0	1499967.BAYZ01000095_gene4168	2.877e-85	297.0	COG3225@1|root,COG3225@2|Bacteria,2NNVN@2323|unclassified Bacteria	2|Bacteria	N	ABC-type uncharacterized transport system	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
SX3_k127_4859853_2	671143.DAMO_0836	3.937e-10	61.0	COG3225@1|root,COG3225@2|Bacteria,2NNVN@2323|unclassified Bacteria	2|Bacteria	N	ABC-type uncharacterized transport system	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
SX3_k127_4859853_1	247490.KSU1_C0525	2.146e-18	98.0	2DN50@1|root,32VJ4@2|Bacteria,2J04A@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
SX3_k127_4865681_1	1463857.JOFZ01000007_gene47	6.878e-13	70.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway	glgA	-	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SX3_k127_4865681_0	1379698.RBG1_1C00001G0655	1.615e-62	229.0	COG0380@1|root,COG0380@2|Bacteria,2NPDG@2323|unclassified Bacteria	2|Bacteria	G	Glycosyltransferase family 20	otsA	-	2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135	ko:K00697,ko:K13057,ko:K20436	ko00500,ko00525,ko01100,ko01130,map00500,map00525,map01100,map01130	M00815	R02737,R08946,R10525,R11239,R11250,R11306,R11497	RC00005,RC00049,RC02748,RC03400,RC03401	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT20,GT4	-	Glyco_transf_20
SX3_k127_4868204_0	864702.OsccyDRAFT_0895	2.165e-80	287.0	COG0596@1|root,COG0596@2|Bacteria,1G21Y@1117|Cyanobacteria,1H751@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SX3_k127_4868204_2	1121104.AQXH01000002_gene713	2.143e-17	90.0	28J26@1|root,2Z8YT@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2914
SX3_k127_4868204_1	926550.CLDAP_30940	2.144e-72	248.0	COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28,4.1.2.27	ko:K01593,ko:K01634	ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034	M00037,M00042,M00100	R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SX3_k127_4876767_0	485915.Dret_1750	2.348e-121	404.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N,XFP,XFP_N
SX3_k127_4876767_1	330214.NIDE3793	8.153e-37	154.0	29W26@1|root,30HKR@2|Bacteria,3J1BV@40117|Nitrospirae	40117|Nitrospirae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4876767_2	649747.HMPREF0083_01759	2.783e-09	60.0	COG1858@1|root,COG1858@2|Bacteria,1V3UY@1239|Firmicutes	1239|Firmicutes	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
SX3_k127_4877294_0	671143.DAMO_2750	1.042e-153	501.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2NNNK@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase X family	polX	-	-	ko:K02347,ko:K04477	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SX3_k127_48977_1	877455.Metbo_0860	1.749e-66	242.0	COG0726@1|root,arCOG02878@2157|Archaea	2157|Archaea	G	deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SX3_k127_48977_0	1254432.SCE1572_46680	1.782e-98	342.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42PY9@68525|delta/epsilon subdivisions,2WMGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	coenzyme F390	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
SX3_k127_48977_2	1227272.HMPREF1556_01756	1.635e-15	90.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,2FSH0@200643|Bacteroidia,22XW8@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
SX3_k127_49013_2	1262915.BN574_00410	2.292e-07	57.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4H4JF@909932|Negativicutes	909932|Negativicutes	L	RNA methyltransferase RsmD family	rsmD	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
SX3_k127_49013_1	421052.F945_00831	1.597e-50	188.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,3NJTZ@468|Moraxellaceae	1236|Gammaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO0053,iSDY_1059.SDY_4064	CTP_transf_like
SX3_k127_49013_0	644966.Tmar_0353	1.354e-78	272.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WCM1@538999|Clostridiales incertae sedis	186801|Clostridia	E	Aminotransferase class I and II	aspB	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS06550	Aminotran_1_2
SX3_k127_4905658_0	78245.Xaut_3704	7.799e-63	223.0	COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,3EYR8@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
SX3_k127_4905658_1	1341151.ASZU01000008_gene1530	2.091e-36	142.0	2DRIA@1|root,33BX1@2|Bacteria,1VY3D@1239|Firmicutes,4HX43@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4905658_2	344747.PM8797T_10219	7.215e-36	144.0	COG2401@1|root,COG2401@2|Bacteria,2IYZ0@203682|Planctomycetes	203682|Planctomycetes	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4910634_3	102232.GLO73106DRAFT_00016010	2.547e-05	53.0	COG1512@1|root,COG1512@2|Bacteria,1G221@1117|Cyanobacteria	1117|Cyanobacteria	S	COG1512 Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SX3_k127_4910634_2	413404.Rmag_0400	2.372e-06	59.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1J5SA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SX3_k127_4910634_1	517418.Ctha_2098	1.297e-71	250.0	COG1028@1|root,COG1028@2|Bacteria,1FEYT@1090|Chlorobi	1090|Chlorobi	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SX3_k127_4910634_0	1499967.BAYZ01000097_gene4346	7.384e-96	320.0	COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9,4.3.1.9	ko:K00384,ko:K03671,ko:K22345	ko00030,ko00450,ko04621,ko05418,map00030,map00450,map04621,map05418	-	R01544,R02016,R03596,R09372	RC00013,RC00544,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913,iPC815.YPO1374	Pyr_redox_2
SX3_k127_4914613_2	649747.HMPREF0083_03976	1.543e-09	62.0	COG1595@1|root,COG1595@2|Bacteria,1U40C@1239|Firmicutes,4HCU0@91061|Bacilli,26S2C@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW11	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SX3_k127_4914613_3	335543.Sfum_1326	5.279e-05	54.0	COG3170@1|root,COG3170@2|Bacteria,1NHGQ@1224|Proteobacteria,42X64@68525|delta/epsilon subdivisions,2WSMQ@28221|Deltaproteobacteria,2MQPS@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF2275,zf-HC2
SX3_k127_4914613_0	289376.THEYE_A1151	1.203e-158	521.0	COG0064@1|root,COG0064@2|Bacteria,3J0FK@40117|Nitrospirae	40117|Nitrospirae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SX3_k127_4914613_1	1382304.JNIL01000001_gene2814	1.142e-111	370.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,2782N@186823|Alicyclobacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SX3_k127_4914794_1	1121930.AQXG01000002_gene1893	2.135e-06	52.0	COG1260@1|root,COG1260@2|Bacteria,4NI0F@976|Bacteroidetes,1IP24@117747|Sphingobacteriia	976|Bacteroidetes	I	Myo-inositol-1-phosphate synthase	ino1	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
SX3_k127_4914794_0	886293.Sinac_6290	2.542e-37	153.0	COG0583@1|root,COG0583@2|Bacteria,2IXKS@203682|Planctomycetes	203682|Planctomycetes	K	Hydrogen peroxide-inducible genes activator	-	-	-	ko:K04761,ko:K11921	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
SX3_k127_4932057_1	1502852.FG94_04755	4.228e-72	258.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2VMB2@28216|Betaproteobacteria,47743@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SX3_k127_4932057_0	309807.SRU_0173	3.229e-78	271.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,4NF3R@976|Bacteroidetes,1FK14@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4,Peptidase_M1
SX3_k127_4936767_3	335541.Swol_2299	1.344e-12	69.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,42JW0@68298|Syntrophomonadaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SX3_k127_4936767_1	247490.KSU1_C1252	6.21e-86	291.0	COG0176@1|root,COG0176@2|Bacteria,2J0IB@203682|Planctomycetes	203682|Planctomycetes	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	TAL_FSA
SX3_k127_4936767_2	1304874.JAFY01000007_gene2036	9.944e-67	245.0	COG0265@1|root,COG0265@2|Bacteria,3TACF@508458|Synergistetes	508458|Synergistetes	M	TIGRFAM periplasmic serine protease, Do DeqQ family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SX3_k127_4936767_0	1121430.JMLG01000005_gene785	2.296e-157	508.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,260RX@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SX3_k127_4938620_0	1121468.AUBR01000030_gene1220	5.464e-101	338.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,42F74@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SX3_k127_4938620_1	1284352.AOIG01000016_gene4039	3.162e-51	199.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,26QJP@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SX3_k127_493983_2	1123253.AUBD01000008_gene408	5.411e-23	112.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1X3FN@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SX3_k127_493983_0	941824.TCEL_01319	4.56e-100	336.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,36EKX@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SX3_k127_493983_1	290397.Adeh_3683	9.793e-57	203.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria	1224|Proteobacteria	F	Deoxynucleoside kinase	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
SX3_k127_4940635_0	880073.Calab_0924	2.714e-49	195.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SX3_k127_4941796_2	457570.Nther_0149	3.644e-17	83.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia	186801|Clostridia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
SX3_k127_4941796_0	411463.EUBVEN_01982	2.762e-44	172.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,25W2D@186806|Eubacteriaceae	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SX3_k127_4941796_1	1121324.CLIT_2c01420	8.339e-27	119.0	COG0389@1|root,COG0389@2|Bacteria,1VEU0@1239|Firmicutes,24RTW@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Cdd1
SX3_k127_4942013_0	1047013.AQSP01000105_gene1443	8.305e-158	506.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SX3_k127_4965944_0	1430331.EP10_00955	8.224e-93	321.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,1WF4W@129337|Geobacillus	91061|Bacilli	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SX3_k127_4965944_1	644282.Deba_1076	3.839e-43	168.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SX3_k127_4967098_0	554065.XP_005849456.1	2.086e-49	189.0	COG0616@1|root,2QQH5@2759|Eukaryota,37JSU@33090|Viridiplantae,34JKR@3041|Chlorophyta	3041|Chlorophyta	OU	protease IV	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SX3_k127_4970139_7	398767.Glov_2162	0.0006215	44.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,42SST@68525|delta/epsilon subdivisions,2WPWN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM PTS system fructose subfamily IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
SX3_k127_4970139_3	1379698.RBG1_1C00001G0555	7.13e-27	119.0	COG3444@1|root,COG3444@2|Bacteria,2NQ0P@2323|unclassified Bacteria	2|Bacteria	G	PTS system sorbose subfamily IIB component	-	-	2.7.1.191	ko:K02794,ko:K19507	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276,M00764	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.6.1.19	-	-	PTSIIB_sorb
SX3_k127_4970139_6	1118060.CAGZ01000005_gene1592	1.7e-06	58.0	COG3715@1|root,COG3715@2|Bacteria,2IC5C@201174|Actinobacteria,4CX3Y@84998|Coriobacteriia	84998|Coriobacteriia	G	PTS system sorbose-specific iic component	-	-	-	-	-	-	-	-	-	-	-	-	EII-Sor
SX3_k127_4970139_5	90371.CY43_23620	8.607e-09	68.0	COG3716@1|root,COG3716@2|Bacteria,1P02J@1224|Proteobacteria,1RPGG@1236|Gammaproteobacteria,3ZJB5@590|Salmonella	1236|Gammaproteobacteria	G	PTS system mannose/fructose/sorbose family IID component	-	-	-	ko:K19509	ko02060,map02060	M00764	-	-	ko00000,ko00001,ko00002,ko02000	4.A.6.1.19	-	-	EIID-AGA
SX3_k127_4970139_4	273068.TTE1820	2.557e-16	82.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,42GZ3@68295|Thermoanaerobacterales	186801|Clostridia	G	phosphocarrier	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
SX3_k127_4970139_0	675812.VHA_003426	9.67e-161	526.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1XSKW@135623|Vibrionales	135623|Vibrionales	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SX3_k127_4970139_2	1121468.AUBR01000012_gene2574	9.519e-69	255.0	COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,42EVQ@68295|Thermoanaerobacterales	186801|Clostridia	G	TIGRFAM bifunctional phosphoglucose phosphomannose isomerase	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
SX3_k127_4970139_1	517418.Ctha_2572	4.698e-73	270.0	COG1209@1|root,COG1209@2|Bacteria,1FD8Z@1090|Chlorobi	1090|Chlorobi	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SX3_k127_4971960_0	635013.TherJR_2896	2.16e-106	356.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,247N7@186801|Clostridia,26040@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SX3_k127_4971960_1	118005.AWNK01000003_gene2294	1.029e-13	83.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
SX3_k127_4973645_0	580331.Thit_1812	1.477e-145	469.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,42F68@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SX3_k127_4973645_2	621372.ACIH01000136_gene1822	8.371e-46	170.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,4HGXD@91061|Bacilli,26WZE@186822|Paenibacillaceae	91061|Bacilli	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SX3_k127_4973645_1	1267535.KB906767_gene248	1.302e-132	429.0	COG0115@1|root,COG0115@2|Bacteria,3Y32X@57723|Acidobacteria,2JI58@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SX3_k127_4973645_3	429009.Adeg_0069	1.037e-26	119.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia,42GVA@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Protein-tyrosine phosphatase, low molecular weight	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SX3_k127_4973645_4	452637.Oter_1881	4.649e-17	83.0	COG1680@1|root,COG4319@1|root,COG1680@2|Bacteria,COG4319@2|Bacteria,46V0A@74201|Verrucomicrobia,3K85Q@414999|Opitutae	414999|Opitutae	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SX3_k127_4980044_1	1120973.AQXL01000133_gene1785	1.303e-23	102.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli	91061|Bacilli	G	Belongs to the GPI family	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SX3_k127_4980044_0	247490.KSU1_D0876	1.638e-55	210.0	COG1477@1|root,COG3901@1|root,COG1477@2|Bacteria,COG3901@2|Bacteria,2IYYX@203682|Planctomycetes	203682|Planctomycetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE,FMN_bind
SX3_k127_4981401_0	1379698.RBG1_1C00001G0436	1.183e-63	242.0	COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SX3_k127_4981401_1	1379698.RBG1_1C00001G0435	2.981e-10	72.0	COG1747@1|root,COG1747@2|Bacteria,2NP33@2323|unclassified Bacteria	2|Bacteria	M	methyltransferase	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N,SprA_N
SX3_k127_4987728_1	439235.Dalk_4359	1.28e-38	146.0	COG0543@1|root,COG0543@2|Bacteria,1NTWI@1224|Proteobacteria,42M66@68525|delta/epsilon subdivisions,2WJJ2@28221|Deltaproteobacteria,2MI36@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	nfnB	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
SX3_k127_4987728_0	1123274.KB899413_gene777	1.572e-191	609.0	COG0493@1|root,COG0493@2|Bacteria,2J5FP@203691|Spirochaetes	203691|Spirochaetes	C	glutamate synthase (NADPH), homotetrameric	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
SX3_k127_498979_0	1189619.pgond44_02018	2.625e-13	83.0	COG1520@1|root,COG1520@2|Bacteria,4NVQ3@976|Bacteroidetes,1IFSJ@117743|Flavobacteriia,4C47J@83612|Psychroflexus	976|Bacteroidetes	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,VCBS
SX3_k127_4989803_5	1123269.NX02_10545	2.67e-10	62.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2TRNJ@28211|Alphaproteobacteria,2K382@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SX3_k127_4989803_4	1280689.AUJC01000003_gene886	4.672e-28	124.0	COG1378@1|root,COG1378@2|Bacteria,1UV3K@1239|Firmicutes,25CS7@186801|Clostridia,36X00@31979|Clostridiaceae	186801|Clostridia	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
SX3_k127_4989803_0	246197.MXAN_4351	5.318e-71	265.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2WJDY@28221|Deltaproteobacteria,2YVHT@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1885	PdxJ
SX3_k127_4989803_3	429009.Adeg_0864	6.578e-37	156.0	COG0860@1|root,COG2861@1|root,COG0860@2|Bacteria,COG2861@2|Bacteria,1V413@1239|Firmicutes,24HY1@186801|Clostridia,42GR2@68295|Thermoanaerobacterales	186801|Clostridia	M	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Amidase_3,Polysacc_deac_2
SX3_k127_4989803_6	518766.Rmar_0713	0.0002252	51.0	2EGU2@1|root,33AK8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_4989803_2	1125863.JAFN01000001_gene1588	2.502e-41	163.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2WN8H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SX3_k127_4989803_1	269799.Gmet_2464	6.003e-59	215.0	COG0084@1|root,COG0535@1|root,COG0084@2|Bacteria,COG0535@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,43TZ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Radical SAM domain protein	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
SX3_k127_4989909_0	926562.Oweho_1435	2.872e-12	78.0	COG2931@1|root,COG3291@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria,4NFV5@976|Bacteroidetes,1I54C@117743|Flavobacteriia,2PAIC@246874|Cryomorphaceae	976|Bacteroidetes	Q	PFAM FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
SX3_k127_4991748_2	1232430.CAVG010000124_gene1254	2.503e-15	78.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,4GY2U@90964|Staphylococcaceae	91061|Bacilli	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SX3_k127_4991748_0	1122176.KB903554_gene3863	1.125e-89	315.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,1IQDT@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SX3_k127_4991748_1	1121472.AQWN01000001_gene159	3.155e-80	273.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,2604A@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM metallophosphoesterase, MG_246 BB_0505 family	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SX3_k127_4996425_0	485913.Krac_3042	7.195e-100	330.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
SX3_k127_4996425_2	56780.SYN_02919	1.612e-33	136.0	COG0350@1|root,COG0500@1|root,COG0350@2|Bacteria,COG2226@2|Bacteria,1N2YQ@1224|Proteobacteria,42TN9@68525|delta/epsilon subdivisions,2WRG0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
SX3_k127_5007534_1	697303.Thewi_2098	1.539e-57	222.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,42FNU@68295|Thermoanaerobacterales	186801|Clostridia	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K10441,ko:K10542	ko02010,map02010	M00212,M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3	-	-	ABC_tran
SX3_k127_5007534_0	180332.JTGN01000005_gene3115	2.397e-68	243.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SX3_k127_5016075_0	344747.PM8797T_26740	1.879e-45	173.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	ko:K04791	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	Acyl_transf_1,HNH_4,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,PP-binding,ketoacyl-synt
SX3_k127_5025372_0	552811.Dehly_0355	1.184e-209	659.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,2G78Z@200795|Chloroflexi,34CMK@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Conserved carboxylase domain	oadA	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
SX3_k127_5028157_1	661478.OP10G_1981	3.479e-44	184.0	COG3876@1|root,COG3876@2|Bacteria	2|Bacteria	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
SX3_k127_5028157_0	667014.Thein_0508	2.88e-78	289.0	COG0747@1|root,COG0747@2|Bacteria,2GHG2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SX3_k127_5037480_1	404380.Gbem_3629	0.0002515	52.0	COG0642@1|root,COG2205@2|Bacteria,1NTNI@1224|Proteobacteria,42YBJ@68525|delta/epsilon subdivisions,2WTR6@28221|Deltaproteobacteria,43TJX@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Sensor histidine kinase, PAS and GAF domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
SX3_k127_5037480_0	1242864.D187_000069	1.066e-62	226.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2YZXT@29|Myxococcales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SX3_k127_5040737_0	1294265.JCM21738_3065	5.434e-12	70.0	COG2309@1|root,COG2309@2|Bacteria,1UMYG@1239|Firmicutes,4HB3B@91061|Bacilli,1ZE38@1386|Bacillus	91061|Bacilli	E	Thermophilic metalloprotease (M29)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
SX3_k127_5042490_0	335543.Sfum_1598	4.077e-114	378.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,2MQB8@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Ftsk_gamma	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SX3_k127_5042490_1	1125863.JAFN01000001_gene3583	5.498e-86	299.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2WITA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
SX3_k127_5056214_0	926561.KB900618_gene161	4.101e-118	392.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3WCB2@53433|Halanaerobiales	186801|Clostridia	E	Cys Met metabolism	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SX3_k127_5056214_1	945713.IALB_2700	4.928e-40	157.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	lrp_1	GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141	-	ko:K03719,ko:K05800	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SX3_k127_5060024_0	309801.trd_A0604	4.717e-58	225.0	COG1122@1|root,COG1122@2|Bacteria,2G6RD@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
SX3_k127_5060024_1	246969.TAM4_850	3.881e-31	141.0	COG0619@1|root,arCOG02250@2157|Archaea,2XV2C@28890|Euryarchaeota	28890|Euryarchaeota	P	ABC-type cobalt transport system, permease component CbiQ and related	cbiQ1	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
SX3_k127_5060024_2	264732.Moth_1863	1.008e-10	68.0	COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,248S9@186801|Clostridia,42FFY@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM	nikMN	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
SX3_k127_5071703_0	883156.HMPREF9282_01514	5.406e-12	79.0	COG2911@1|root,COG2911@2|Bacteria,1TQZZ@1239|Firmicutes,4H2F1@909932|Negativicutes	909932|Negativicutes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	AsmA_2,TamB
SX3_k127_5080_0	945713.IALB_2955	2.265e-131	433.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
SX3_k127_5086248_0	404380.Gbem_2934	1.79e-90	305.0	COG1232@1|root,COG1232@2|Bacteria,1MX35@1224|Proteobacteria,42QDK@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SX3_k127_5086248_1	880074.BARVI_11340	2.826e-41	157.0	COG2246@1|root,COG2246@2|Bacteria,4NXZ2@976|Bacteroidetes	976|Bacteroidetes	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SX3_k127_5086248_2	861299.J421_0244	1.102e-23	106.0	COG3682@1|root,COG3682@2|Bacteria,1ZV5U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SX3_k127_508732_1	421052.F945_00090	0.0004087	50.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,3NJEZ@468|Moraxellaceae	1236|Gammaproteobacteria	M	OmpW family	ompW1	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
SX3_k127_508732_0	861299.J421_1066	4.909e-07	56.0	COG3637@1|root,COG3637@2|Bacteria,1ZU6Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
SX3_k127_5096712_0	1123376.AUIU01000016_gene335	9.878e-37	156.0	COG0457@1|root,COG0457@2|Bacteria,3J0MH@40117|Nitrospirae	40117|Nitrospirae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
SX3_k127_5110650_0	1047013.AQSP01000094_gene32	1.145e-173	558.0	COG0017@1|root,COG0017@2|Bacteria,2NNQM@2323|unclassified Bacteria	2|Bacteria	J	tRNA synthetases class II (D, K and N)	asnS	GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SX3_k127_5115423_0	273068.TTE0582	9.049e-201	635.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,42EYV@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
SX3_k127_5115423_1	1047013.AQSP01000076_gene1478	1.407e-33	143.0	COG1600@1|root,COG1600@2|Bacteria,2NRKC@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_16,Fer4_7
SX3_k127_5122776_0	1122947.FR7_3293	5.326e-75	260.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,4H1Y3@909932|Negativicutes	909932|Negativicutes	J	elongation factor G	fusA_1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SX3_k127_5122776_1	1291050.JAGE01000001_gene3033	2.144e-10	70.0	2EC4I@1|root,3363E@2|Bacteria,1VJH4@1239|Firmicutes,25E22@186801|Clostridia	186801|Clostridia	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
SX3_k127_5122776_2	1121943.KB899994_gene1013	3.278e-10	67.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XHRM@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the peptidase S1C family	mucD	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SX3_k127_5124155_0	1191523.MROS_1530	9.548e-141	466.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
SX3_k127_5131959_0	879212.DespoDRAFT_00867	3.768e-152	503.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MIP0@213118|Desulfobacterales	68525|delta/epsilon subdivisions	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
SX3_k127_5133047_0	373903.Hore_13580	1.089e-106	362.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3WC51@53433|Halanaerobiales	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
SX3_k127_5162382_0	1121930.AQXG01000001_gene1216	1.379e-22	111.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Beta_helix,F5_F8_type_C
SX3_k127_5162382_1	1121866.AUGK01000018_gene823	1.32e-05	57.0	COG3049@1|root,COG3049@2|Bacteria	2|Bacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	AAT,CBAH
SX3_k127_5166931_3	1123274.KB899427_gene3350	5.707e-33	134.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsN3	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
SX3_k127_5166931_4	1123274.KB899427_gene3351	2.871e-29	130.0	COG0589@1|root,COG0589@2|Bacteria,2J7EV@203691|Spirochaetes	203691|Spirochaetes	T	universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SX3_k127_5166931_1	1123274.KB899427_gene3352	5.177e-53	194.0	COG1394@1|root,COG1394@2|Bacteria,2J5V1@203691|Spirochaetes	203691|Spirochaetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
SX3_k127_5166931_0	573413.Spirs_3107	7.724e-213	669.0	COG1156@1|root,COG1156@2|Bacteria,2J5SP@203691|Spirochaetes	203691|Spirochaetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
SX3_k127_5166931_2	158189.SpiBuddy_1148	2.124e-51	186.0	COG1155@1|root,COG1155@2|Bacteria,2J5EF@203691|Spirochaetes	203691|Spirochaetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
SX3_k127_5167926_0	1232410.KI421415_gene3124	6.374e-63	237.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,43SDF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PAS domain	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
SX3_k127_517659_2	1121468.AUBR01000007_gene242	3.13e-92	310.0	COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,42FG2@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
SX3_k127_517659_1	1158318.ATXC01000001_gene195	5.028e-105	352.0	COG1013@1|root,COG1013@2|Bacteria,2G42W@200783|Aquificae	200783|Aquificae	C	TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SX3_k127_517659_3	316067.Geob_2668	1.503e-57	214.0	COG1014@1|root,COG1014@2|Bacteria,1RAQ4@1224|Proteobacteria,43BEE@68525|delta/epsilon subdivisions,2WN0D@28221|Deltaproteobacteria,43TV8@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	korC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
SX3_k127_517659_0	909663.KI867150_gene284	2.823e-200	633.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria,2MQ89@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
SX3_k127_5180141_1	688269.Theth_1602	6.226e-10	62.0	COG0834@1|root,COG2206@1|root,COG0834@2|Bacteria,COG2206@2|Bacteria,2GCEF@200918|Thermotogae	200918|Thermotogae	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	-	-	-	-	-	-	-	-	-	HD,SBP_bac_3
SX3_k127_5180141_0	477974.Daud_1631	8.281e-115	380.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,25ZYS@186807|Peptococcaceae	186801|Clostridia	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SX3_k127_5181615_2	880073.Calab_0041	7.736e-08	54.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
SX3_k127_5181615_0	1121468.AUBR01000008_gene2068	3.189e-54	198.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,42GC6@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SX3_k127_5181615_1	1379698.RBG1_1C00001G0723	3.815e-08	64.0	COG0860@1|root,COG0860@2|Bacteria,2NPCZ@2323|unclassified Bacteria	2|Bacteria	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
SX3_k127_5182156_2	552811.Dehly_0623	5.886e-41	156.0	COG3383@1|root,COG3383@2|Bacteria,2GAS8@200795|Chloroflexi,34D7W@301297|Dehalococcoidia	301297|Dehalococcoidia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4
SX3_k127_5182156_1	429009.Adeg_0158	3.235e-42	161.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24I29@186801|Clostridia,42ICW@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SX3_k127_5182156_0	644282.Deba_2839	1.607e-61	214.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.12.1.3,1.6.5.3	ko:K00124,ko:K00335,ko:K18331	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
SX3_k127_5182773_0	1379698.RBG1_1C00001G1368	3.412e-16	90.0	COG4219@1|root,COG4219@2|Bacteria,2NS3V@2323|unclassified Bacteria	2|Bacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6,DUF4309,DUF5301
SX3_k127_5185206_0	1469607.KK073768_gene3281	1.614e-50	185.0	COG3321@1|root,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1HJVE@1161|Nostocales	1117|Cyanobacteria	Q	COGs COG3321 Polyketide synthase modules and related protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,ketoacyl-synt
SX3_k127_5185206_1	1157634.KB912992_gene5891	1.638e-30	126.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
SX3_k127_519658_0	1209989.TepiRe1_1817	2.63e-135	462.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SX3_k127_519658_1	667014.Thein_1849	9.118e-56	201.0	COG0059@1|root,COG0059@2|Bacteria,2GH4M@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SX3_k127_5208617_1	1265505.ATUG01000001_gene3174	1.947e-27	113.0	COG1042@1|root,COG1042@2|Bacteria,1R8Q6@1224|Proteobacteria,42NR2@68525|delta/epsilon subdivisions,2WM2A@28221|Deltaproteobacteria,2MN2C@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_2,Succ_CoA_lig
SX3_k127_5208617_0	1125863.JAFN01000001_gene3212	1.231e-60	219.0	COG0045@1|root,COG0045@2|Bacteria,1RHNF@1224|Proteobacteria,42TCD@68525|delta/epsilon subdivisions,2WPBK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5
SX3_k127_5217902_6	887898.HMPREF0551_0760	7.805e-12	76.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,1K0T3@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
SX3_k127_5217902_4	667015.Bacsa_2794	4.702e-34	140.0	COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,2FM5H@200643|Bacteroidia,4AM6P@815|Bacteroidaceae	976|Bacteroidetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SX3_k127_5217902_5	266762.HQ36_05900	3.608e-15	88.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,2FPK9@200643|Bacteroidia,22X9M@171551|Porphyromonadaceae	976|Bacteroidetes	Q	Virulence factor Mce family protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SX3_k127_5217902_1	1379698.RBG1_1C00001G0979	1.115e-89	302.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SX3_k127_5217902_2	1379698.RBG1_1C00001G0978	2.274e-73	255.0	COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SX3_k127_5217902_0	671143.DAMO_0515	6.944e-146	486.0	COG0305@1|root,COG0305@2|Bacteria,2NNKG@2323|unclassified Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SX3_k127_5217902_3	1379698.RBG1_1C00001G0976	1.07e-60	217.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	ung	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SX3_k127_5230503_0	204669.Acid345_4203	4.926e-114	377.0	COG1297@1|root,COG1297@2|Bacteria,3Y2UT@57723|Acidobacteria,2JHIU@204432|Acidobacteriia	204432|Acidobacteriia	S	Oligopeptide transporter OPT	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SX3_k127_5230503_1	502025.Hoch_1456	1.557e-74	270.0	COG1716@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2Z3I1@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Response_reg,Sigma54_activat
SX3_k127_5232882_0	1042163.BRLA_c001650	1.155e-89	304.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,26SRZ@186822|Paenibacillaceae	91061|Bacilli	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SX3_k127_5232882_1	866775.HMPREF9243_0394	3.245e-55	197.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli,27DYK@186827|Aerococcaceae	91061|Bacilli	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SX3_k127_5232882_2	748280.NH8B_0346	8.821e-42	157.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,2VKUA@28216|Betaproteobacteria,2KPFZ@206351|Neisseriales	206351|Neisseriales	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SX3_k127_5232882_6	42256.RradSPS_1955	5.633e-06	53.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4CQ4I@84995|Rubrobacteria	84995|Rubrobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SX3_k127_5232882_5	177437.HRM2_36380	1.389e-06	53.0	COG0690@1|root,COG0690@2|Bacteria,1Q1BI@1224|Proteobacteria,42X4Z@68525|delta/epsilon subdivisions,2WSQ8@28221|Deltaproteobacteria,2MKUQ@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SX3_k127_5232882_4	1392493.JIAB01000001_gene1887	1.226e-17	83.0	COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,24QK0@186801|Clostridia,27PFN@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SX3_k127_5232882_3	1306947.ARQD01000002_gene522	1.925e-20	91.0	COG0050@1|root,COG0050@2|Bacteria,2NNQV@2323|unclassified Bacteria	2|Bacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484	-	ko:K02358,ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	3.A.1.1.16,3.A.1.1.2	-	iSB619.SA_RS02960	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SX3_k127_5248298_3	319225.Plut_0134	3.501e-13	72.0	COG0416@1|root,COG0416@2|Bacteria,1FDBT@1090|Chlorobi	1090|Chlorobi	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SX3_k127_5248298_2	1379698.RBG1_1C00001G1829	1.593e-17	83.0	COG0333@1|root,COG0333@2|Bacteria,2NQ1M@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal L32p protein family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SX3_k127_5248298_1	1379698.RBG1_1C00001G1830	2.92e-19	94.0	COG1399@1|root,COG1399@2|Bacteria,2NPVD@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1399	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SX3_k127_5248298_0	572546.Arcpr_0498	1.417e-24	104.0	COG0105@1|root,arCOG04313@2157|Archaea,2XWSK@28890|Euryarchaeota,2465T@183980|Archaeoglobi	183980|Archaeoglobi	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SX3_k127_5256639_0	1034943.BN1094_00934	2.123e-09	70.0	COG1879@1|root,COG2373@1|root,COG3419@1|root,COG1879@2|Bacteria,COG2373@2|Bacteria,COG3419@2|Bacteria,1QUUR@1224|Proteobacteria,1T21Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Psort location OuterMembrane, score	eaeH	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_1,Big_2,IAT_beta,Invasin_D3,LysM
SX3_k127_5259518_0	696369.KI912183_gene972	5.844e-62	228.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,263P9@186807|Peptococcaceae	186801|Clostridia	E	Pyridine nucleotide-disulphide oxidoreductase	sfrB	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2
SX3_k127_5261784_1	573370.DMR_44360	4.873e-16	79.0	2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria,42X36@68525|delta/epsilon subdivisions,2WSNU@28221|Deltaproteobacteria,2MDMZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5261784_2	1121445.ATUZ01000020_gene2152	1.379e-07	58.0	COG2192@1|root,COG2192@2|Bacteria	2|Bacteria	O	nodulation	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SX3_k127_5261784_0	1123277.KB893217_gene4672	1.121e-92	309.0	COG2192@1|root,COG2192@2|Bacteria,4NEV9@976|Bacteroidetes,47JR5@768503|Cytophagia	976|Bacteroidetes	O	PFAM Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SX3_k127_5262649_3	754027.HMPREF9554_00830	1.355e-20	96.0	COG0759@1|root,COG0759@2|Bacteria,2J8TC@203691|Spirochaetes	203691|Spirochaetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SX3_k127_5262649_4	1408439.JHXW01000010_gene172	3.041e-11	70.0	COG0594@1|root,COG0594@2|Bacteria,37AC7@32066|Fusobacteria	32066|Fusobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SX3_k127_5262649_5	485918.Cpin_1055	2.622e-09	63.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,1IU87@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SX3_k127_5262649_0	1157490.EL26_22055	1.798e-142	465.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,277VV@186823|Alicyclobacillaceae	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SX3_k127_5262649_1	1379270.AUXF01000002_gene1191	8.676e-82	286.0	COG0592@1|root,COG0592@2|Bacteria,1ZT22@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_3
SX3_k127_5262649_2	1246626.BleG1_4000	3.686e-32	133.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,1ZC8V@1386|Bacillus	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SX3_k127_526647_0	1123386.AUIW01000001_gene329	6.17e-08	66.0	COG2197@1|root,COG2197@2|Bacteria,1WIZJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SX3_k127_526647_1	1121920.AUAU01000004_gene603	1.158e-06	59.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
SX3_k127_5275813_1	338966.Ppro_0588	3.271e-93	321.0	COG1009@1|root,COG1009@2|Bacteria,1QV11@1224|Proteobacteria,43CGR@68525|delta/epsilon subdivisions,2X7RW@28221|Deltaproteobacteria	1224|Proteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
SX3_k127_5275813_8	797302.Halru_1594	5.238e-16	85.0	COG1563@1|root,COG2111@1|root,arCOG03077@2157|Archaea,arCOG03078@2157|Archaea,2XX82@28890|Euryarchaeota,23V8W@183963|Halobacteria	183963|Halobacteria	P	Multisubunit Na H antiporter, MnhB subunit	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040
SX3_k127_5275813_7	1499967.BAYZ01000135_gene94	3.969e-18	90.0	COG2111@1|root,COG2111@2|Bacteria,2NPU9@2323|unclassified Bacteria	2|Bacteria	P	Domain related to MnhB subunit of Na+/H+ antiporter	mnhB	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MnhB
SX3_k127_5275813_6	604354.TSIB_1912	6.403e-21	96.0	COG1006@1|root,arCOG03072@2157|Archaea,2XXRN@28890|Euryarchaeota,2447I@183968|Thermococci	183968|Thermococci	P	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	1.6.5.3	ko:K00340,ko:K05567	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Oxidored_q2
SX3_k127_5275813_0	521045.Kole_0565	2.974e-104	356.0	COG0651@1|root,COG0651@2|Bacteria,2GE49@200918|Thermotogae	200918|Thermotogae	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
SX3_k127_5275813_3	70601.3257880	8.187e-33	135.0	COG1863@1|root,arCOG03099@2157|Archaea,2XTHH@28890|Euryarchaeota,2430X@183968|Thermococci	183968|Thermococci	P	Na+/H+ ion antiporter subunit	-	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
SX3_k127_5275813_9	237368.SCABRO_02536	1.591e-11	74.0	COG2212@1|root,COG2212@2|Bacteria,2J1KY@203682|Planctomycetes	203682|Planctomycetes	P	Multiple resistance and pH regulation protein F (MrpF / PhaF)	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
SX3_k127_5275813_4	521045.Kole_0562	6.039e-31	125.0	COG1320@1|root,COG1320@2|Bacteria	2|Bacteria	P	monovalent cation:proton antiporter activity	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
SX3_k127_5275813_2	521045.Kole_0561	1.682e-34	140.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	ko:K12143	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Flavodoxin_5
SX3_k127_5275813_5	269796.Rru_A0322	7.098e-25	110.0	COG0680@1|root,COG0680@2|Bacteria,1R3V7@1224|Proteobacteria,2UMM4@28211|Alphaproteobacteria,2JY79@204441|Rhodospirillales	204441|Rhodospirillales	C	Hydrogenase maturation protease	-	-	3.4.23.51	ko:K08315	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
SX3_k127_5276663_0	485913.Krac_9732	2.236e-50	197.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,DLH,Peptidase_S9
SX3_k127_5276663_1	1463926.JOCA01000006_gene3963	1e-09	63.0	COG0662@1|root,COG0662@2|Bacteria,2INXJ@201174|Actinobacteria	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SX3_k127_527847_3	1382306.JNIM01000001_gene1815	3.995e-07	64.0	COG0237@1|root,COG0237@2|Bacteria,2G6RQ@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
SX3_k127_527847_0	338963.Pcar_0592	1.878e-244	783.0	COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,43RY4@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase A domain	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SX3_k127_527847_1	1089553.Tph_c21540	7.818e-38	154.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,42EM4@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SX3_k127_527847_2	1410608.JNKX01000025_gene528	1.128e-08	66.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,2FNAY@200643|Bacteroidia,4AWAX@815|Bacteroidaceae	976|Bacteroidetes	S	outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
SX3_k127_5279125_0	635013.TherJR_1781	1.052e-121	396.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,260I8@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
SX3_k127_5279125_1	1125863.JAFN01000001_gene30	2.633e-53	194.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2WNK6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SX3_k127_5279349_0	880073.Calab_0680	3.237e-32	128.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SX3_k127_5279349_1	595460.RRSWK_07016	3.593e-13	81.0	COG2304@1|root,COG2304@2|Bacteria,2IYB0@203682|Planctomycetes	203682|Planctomycetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5281632_4	984262.SGRA_0778	9.051e-46	171.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1IQZT@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SX3_k127_5281632_1	595536.ADVE02000001_gene3256	9.081e-70	244.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2TR14@28211|Alphaproteobacteria,36XIS@31993|Methylocystaceae	28211|Alphaproteobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SX3_k127_5281632_6	266117.Rxyl_2978	4.892e-34	138.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4CQHA@84995|Rubrobacteria	84995|Rubrobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SX3_k127_5281632_3	986075.CathTA2_2625	7.643e-49	191.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli	91061|Bacilli	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS02535	Thymidylate_kin
SX3_k127_5281632_0	459349.CLOAM0355	7.618e-110	374.0	COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SX3_k127_5281632_5	935948.KE386494_gene836	4.674e-40	164.0	COG4359@1|root,COG4359@2|Bacteria,1TSZ9@1239|Firmicutes,24IHI@186801|Clostridia,42GA1@68295|Thermoanaerobacterales	186801|Clostridia	E	HAD-superfamily hydrolase, subfamily IB, PSPase-like	mtnX	-	-	-	-	-	-	-	-	-	-	-	HAD,Put_Phosphatase
SX3_k127_5281632_2	880073.Calab_0866	2.728e-49	187.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	luxD	-	3.2.1.4,4.2.99.18	ko:K01179,ko:K06889,ko:K10773,ko:K15853	ko00500,ko01100,ko02020,ko02024,ko03410,map00500,map01100,map02020,map02024,map03410	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko03400	-	GH5,GH9	-	Abhydrolase_1,Acyl_transf_2,DLH,Hydrolase_4,Peptidase_S9
SX3_k127_5282772_1	313603.FB2170_00325	7.809e-10	72.0	COG3509@1|root,COG3975@1|root,COG3509@2|Bacteria,COG3975@2|Bacteria,4NFU9@976|Bacteroidetes,1HZST@117743|Flavobacteriia	976|Bacteroidetes	Q	depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5282772_0	1198114.AciX9_0586	1.598e-23	114.0	COG3206@1|root,COG3206@2|Bacteria,3Y2PJ@57723|Acidobacteria,2JHP9@204432|Acidobacteriia	204432|Acidobacteriia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
SX3_k127_5290352_3	880072.Desac_0855	9.529e-10	71.0	COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42SCI@68525|delta/epsilon subdivisions,2WPWT@28221|Deltaproteobacteria,2MQHM@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SX3_k127_5290352_4	1122179.KB890420_gene2490	1.316e-06	62.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8,YfiO
SX3_k127_5290352_2	796940.HMPREF9628_01084	2.212e-15	91.0	COG0760@1|root,COG0760@2|Bacteria,1V5Q2@1239|Firmicutes,248JQ@186801|Clostridia,25T9R@186804|Peptostreptococcaceae	186801|Clostridia	O	PPIC-type PPIASE domain	prsA2	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
SX3_k127_5290352_0	1121468.AUBR01000001_gene508	1.072e-83	290.0	COG0836@1|root,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia,42FA6@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Nucleotidyl transferase	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
SX3_k127_5290352_1	1123371.ATXH01000009_gene1104	8.253e-72	247.0	COG1109@1|root,COG1109@2|Bacteria,2GHQ7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SX3_k127_5291269_1	1235797.C816_02602	2.726e-30	125.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,2N6ZJ@216572|Oscillospiraceae	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SX3_k127_5291269_0	717605.Theco_2324	2.676e-40	160.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,26S7A@186822|Paenibacillaceae	91061|Bacilli	M	Stage V sporulation protein d	pbpX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
SX3_k127_5296151_0	1487953.JMKF01000037_gene3241	2.227e-32	144.0	COG1680@1|root,COG2931@1|root,COG1680@2|Bacteria,COG2931@2|Bacteria,1G5C3@1117|Cyanobacteria,1HAVU@1150|Oscillatoriales	1117|Cyanobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SX3_k127_529696_0	177437.HRM2_19940	1.635e-22	108.0	COG0438@1|root,COG0438@2|Bacteria,1NCUN@1224|Proteobacteria,42WRQ@68525|delta/epsilon subdivisions,2WS5Y@28221|Deltaproteobacteria,2MN5B@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SX3_k127_530427_0	247490.KSU1_C0449	4.584e-63	241.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
SX3_k127_530427_2	1185766.DL1_11185	4.566e-22	110.0	COG1621@1|root,COG1621@2|Bacteria,1MXR3@1224|Proteobacteria,2U17S@28211|Alphaproteobacteria,2XNYE@285107|Thioclava	28211|Alphaproteobacteria	G	Glycosyl hydrolases family 32 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_32N
SX3_k127_530427_1	1226994.AMZB01000121_gene3420	1.672e-25	117.0	COG1846@1|root,COG1846@2|Bacteria,1RF3U@1224|Proteobacteria,1S4H8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SX3_k127_5311456_1	1265505.ATUG01000002_gene2684	3.125e-82	280.0	COG0280@1|root,COG3426@1|root,COG0280@2|Bacteria,COG3426@2|Bacteria,1QTXP@1224|Proteobacteria,42RGR@68525|delta/epsilon subdivisions,2WNWC@28221|Deltaproteobacteria,2MKSE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acetokinase family	-	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase,Cupin_2,PTA_PTB
SX3_k127_5311456_0	1379698.RBG1_1C00001G0370	2.515e-92	323.0	COG0616@1|root,COG0616@2|Bacteria,2NNKU@2323|unclassified Bacteria	2|Bacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SX3_k127_5324472_1	663278.Ethha_0976	1.371e-29	121.0	COG4231@1|root,COG4231@2|Bacteria,1VAJQ@1239|Firmicutes,24MVB@186801|Clostridia	186801|Clostridia	C	PFAM 4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
SX3_k127_5324472_2	1429916.X566_03530	9.76e-10	71.0	COG2271@1|root,COG2271@2|Bacteria,1NJTU@1224|Proteobacteria,2TUBJ@28211|Alphaproteobacteria,3JU19@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	MA20_01130	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SX3_k127_5324472_0	880073.Calab_2786	1.663e-68	249.0	COG1355@1|root,COG1355@2|Bacteria,2NQS3@2323|unclassified Bacteria	2|Bacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
SX3_k127_5329305_0	290317.Cpha266_0557	1.403e-42	177.0	COG3074@1|root,COG3074@2|Bacteria,1FFHR@1090|Chlorobi	1090|Chlorobi	D	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5329305_1	1120985.AUMI01000016_gene1879	2.925e-30	128.0	2FEBN@1|root,346BD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5349230_0	338966.Ppro_1153	3.868e-165	531.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43UES@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SX3_k127_5349230_1	1125863.JAFN01000001_gene1610	2.165e-159	535.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
SX3_k127_5369760_5	517418.Ctha_1867	1.613e-05	53.0	COG4219@1|root,COG4219@2|Bacteria,1FF12@1090|Chlorobi	1090|Chlorobi	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5369760_0	1191523.MROS_2571	8.363e-46	177.0	COG0811@1|root,COG0811@2|Bacteria	2|Bacteria	U	bacteriocin transport	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
SX3_k127_5369760_2	880073.Calab_2425	2.709e-19	92.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SX3_k127_5369760_4	880073.Calab_2426	6.814e-16	85.0	COG0848@1|root,COG0848@2|Bacteria,2NRQH@2323|unclassified Bacteria	2|Bacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SX3_k127_5369760_3	880073.Calab_1495	2.767e-18	93.0	COG0810@1|root,COG0810@2|Bacteria,2NQ1D@2323|unclassified Bacteria	2|Bacteria	M	Gram-negative bacterial TonB protein C-terminal	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SX3_k127_5369760_1	1392502.JNIO01000002_gene605	1.445e-32	143.0	COG1538@1|root,COG1538@2|Bacteria,1TQ0W@1239|Firmicutes,4H3MR@909932|Negativicutes	909932|Negativicutes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SX3_k127_5371658_3	880073.Calab_3215	4.651e-18	94.0	COG0366@1|root,COG0708@1|root,COG0366@2|Bacteria,COG0708@2|Bacteria,2NREA@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 70	-	-	3.1.11.2,3.2.1.1	ko:K01142,ko:K01176	ko00500,ko01100,ko03410,ko04973,map00500,map01100,map03410,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000,ko03400	-	GH13	-	Alpha-amylase,CBM_25,DUF1939,He_PIG
SX3_k127_5371658_4	909663.KI867150_gene1619	2.61e-16	87.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,42W54@68525|delta/epsilon subdivisions,2WR8H@28221|Deltaproteobacteria,2MSEJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SX3_k127_5371658_1	880072.Desac_2642	5.847e-64	234.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WN1U@28221|Deltaproteobacteria,2MSIW@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SX3_k127_5371658_2	871968.DESME_02320	3.245e-35	145.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24MUB@186801|Clostridia,2657X@186807|Peptococcaceae	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
SX3_k127_5371658_0	891968.Anamo_1584	4.976e-86	287.0	COG0438@1|root,COG0438@2|Bacteria,3TAFG@508458|Synergistetes	508458|Synergistetes	H	PFAM glycosyl transferase group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
SX3_k127_5377752_0	1121422.AUMW01000009_gene3340	1.716e-240	752.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,2618A@186807|Peptococcaceae	186801|Clostridia	C	Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
SX3_k127_5377752_1	646529.Desaci_1174	8.332e-73	253.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,261PP@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM glycyl-radical enzyme activating protein family	csdA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
SX3_k127_5382882_1	313606.M23134_01907	1.214e-26	114.0	COG0793@1|root,COG0793@2|Bacteria,4NM82@976|Bacteroidetes,47PRW@768503|Cytophagia	976|Bacteroidetes	M	N-terminal domain of Peptidase_S41 in eukaryotic IRBP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Peptidase_S41_N,TPR_2
SX3_k127_5382882_4	68199.JNZO01000014_gene3746	9.866e-08	63.0	COG2230@1|root,COG2230@2|Bacteria,2I2YV@201174|Actinobacteria	201174|Actinobacteria	M	Methyltransferase domain	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0044237,GO:0044249	2.1.1.254	ko:K14369	ko00522,ko01130,map00522,map01130	M00774	R05520,R05532	RC00003,RC01324	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	Methyltransf_11
SX3_k127_5382882_2	1379698.RBG1_1C00001G0668	4.483e-19	102.0	COG2885@1|root,COG5276@1|root,COG2885@2|Bacteria,COG5276@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	3.4.24.40	ko:K01406,ko:K21449	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	DUF1566,Phenol_MetA_deg
SX3_k127_5382882_0	1123278.KB893427_gene1235	4.794e-52	204.0	2AQ5P@1|root,31FB4@2|Bacteria,4NRIU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5382882_3	459349.CLOAM1071	8.552e-16	91.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CARDB,Cadherin-like,DUF4091
SX3_k127_5383638_1	1121365.AQXB01000001_gene928	7.797e-11	67.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,22KWD@1653|Corynebacteriaceae	201174|Actinobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2870c	DXPR_C,DXP_redisom_C,DXP_reductoisom
SX3_k127_5383638_0	1499967.BAYZ01000078_gene990	1.647e-42	166.0	COG4589@1|root,COG4589@2|Bacteria,2NPVB@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06255	CTP_transf_1
SX3_k127_538578_4	1089553.Tph_c06540	2.534e-05	56.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,42FMA@68295|Thermoanaerobacterales	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SX3_k127_538578_1	880073.Calab_1944	2.699e-68	244.0	COG2884@1|root,COG2884@2|Bacteria,2NP95@2323|unclassified Bacteria	2|Bacteria	D	ATPases associated with a variety of cellular activities	ftsE	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SX3_k127_538578_0	644282.Deba_2731	1.026e-69	248.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
SX3_k127_538578_3	459349.CLOAM0180	4.551e-13	72.0	COG1188@1|root,COG1188@2|Bacteria,2NQ1V@2323|unclassified Bacteria	2|Bacteria	J	S4 RNA-binding domain	yabO	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	DUF3558,S4
SX3_k127_538578_2	861299.J421_3745	2.535e-35	150.0	COG0760@1|root,COG0760@2|Bacteria,1ZSU2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
SX3_k127_538633_4	1449342.JQMR01000001_gene1286	5.418e-09	61.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli,27FRS@186828|Carnobacteriaceae	91061|Bacilli	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SX3_k127_538633_3	398767.Glov_1921	3.319e-28	131.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,42N32@68525|delta/epsilon subdivisions,2WKBN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM Peptidase M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3
SX3_k127_538633_2	517418.Ctha_0331	1.286e-30	137.0	COG2812@1|root,COG2812@2|Bacteria,1FDCZ@1090|Chlorobi	1090|Chlorobi	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
SX3_k127_538633_1	401526.TcarDRAFT_1922	2.814e-72	253.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,4H2TJ@909932|Negativicutes	909932|Negativicutes	S	PSP1 C-terminal domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
SX3_k127_538633_0	1121468.AUBR01000004_gene160	2.211e-124	413.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,42EPT@68295|Thermoanaerobacterales	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
SX3_k127_5393873_0	370438.PTH_0900	5.139e-135	459.0	COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,248RS@186801|Clostridia,2608I@186807|Peptococcaceae	186801|Clostridia	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
SX3_k127_5393873_1	643648.Slip_1629	3.284e-123	409.0	COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,24AU0@186801|Clostridia,42JHM@68298|Syntrophomonadaceae	186801|Clostridia	J	Glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
SX3_k127_5393873_4	396014.BF93_06230	1.943e-11	75.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4FBQT@85020|Dermabacteraceae	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SX3_k127_5393873_2	926692.AZYG01000007_gene1279	2.511e-44	169.0	COG2928@1|root,COG2928@2|Bacteria,1V6FM@1239|Firmicutes,24JQ1@186801|Clostridia,3WBT4@53433|Halanaerobiales	186801|Clostridia	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
SX3_k127_5393873_3	880072.Desac_1749	1.558e-18	87.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WJV1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SX3_k127_5416368_0	1047013.AQSP01000037_gene1326	8.515e-117	380.0	COG1830@1|root,COG1830@2|Bacteria,2NPYC@2323|unclassified Bacteria	2|Bacteria	G	DeoC/LacD family aldolase	lsrF	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747	2.3.1.245,4.1.2.13	ko:K08321,ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko02024,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map02024	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SX3_k127_5416368_1	1121406.JAEX01000001_gene259	1.834e-13	76.0	COG1456@1|root,COG1456@2|Bacteria,1R6BH@1224|Proteobacteria,42NKF@68525|delta/epsilon subdivisions,2WJ72@28221|Deltaproteobacteria,2MA2C@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase delta subunit, TIM barrel	-	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
SX3_k127_5430718_1	573413.Spirs_0602	1.752e-58	204.0	COG1592@1|root,COG1592@2|Bacteria,2J5MR@203691|Spirochaetes	203691|Spirochaetes	C	Rubrerythrin	rbr	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SX3_k127_5430718_0	596151.DesfrDRAFT_3521	8.657e-62	214.0	COG2033@1|root,COG2033@2|Bacteria,1RHE0@1224|Proteobacteria,42SB9@68525|delta/epsilon subdivisions,2WP2D@28221|Deltaproteobacteria,2MBEZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Desulfoferrodoxin ferrous iron-binding region	dfx	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
SX3_k127_5430718_2	1343739.PAP_08895	3.564e-41	154.0	COG1528@1|root,arCOG01095@2157|Archaea,2XXEN@28890|Euryarchaeota,243SC@183968|Thermococci	183968|Thermococci	P	Ferritin-like domain	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
SX3_k127_5430774_1	1379698.RBG1_1C00001G1080	2.841e-56	211.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SX3_k127_5430774_2	161528.ED21_26108	1.268e-23	103.0	COG3655@1|root,COG3655@2|Bacteria,1N6VH@1224|Proteobacteria,2UFAM@28211|Alphaproteobacteria,2K6RE@204457|Sphingomonadales	204457|Sphingomonadales	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
SX3_k127_5430774_0	1047013.AQSP01000142_gene180	7.247e-299	925.0	COG3537@1|root,COG3537@2|Bacteria,2NQQ0@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
SX3_k127_5436271_0	945713.IALB_2905	6.663e-49	189.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5436271_1	1191523.MROS_1357	1.698e-17	91.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.2.1.99	ko:K06113,ko:K12685	-	-	-	-	ko00000,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	GH43	-	Cu_amine_oxidN1,Peptidase_S8,PrcB_C,SLH
SX3_k127_543885_2	767817.Desgi_1165	1.063e-20	93.0	COG1941@1|root,COG1941@2|Bacteria,1V21E@1239|Firmicutes,24GWD@186801|Clostridia	186801|Clostridia	C	PFAM NADH ubiquinone oxidoreductase, 20	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
SX3_k127_543885_0	429009.Adeg_2015	1.044e-64	224.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,42GG4@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD,NADH_4Fe-4S
SX3_k127_543885_1	1379698.RBG1_1C00001G0050	3.018e-51	184.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2,Pyr_redox_3
SX3_k127_544426_0	234267.Acid_3262	4.902e-116	397.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	234267.Acid_3262|-	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SX3_k127_5450222_1	868131.MSWAN_1884	3.317e-54	195.0	COG1145@1|root,arCOG00296@2157|Archaea,2XUE5@28890|Euryarchaeota	28890|Euryarchaeota	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_21,Fer4_9
SX3_k127_5450222_0	1304888.ATWF01000001_gene1301	8.861e-108	357.0	COG0428@1|root,COG0428@2|Bacteria,2GFCI@200930|Deferribacteres	200930|Deferribacteres	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SX3_k127_5450222_2	1121440.AUMA01000003_gene3033	0.0001278	45.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MRV@68525|delta/epsilon subdivisions,2WK9C@28221|Deltaproteobacteria,2M8SQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit	porB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SX3_k127_5450364_0	86416.Clopa_0047	8.378e-86	294.0	COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,24CJP@186801|Clostridia,36GCY@31979|Clostridiaceae	186801|Clostridia	Q	PFAM Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SX3_k127_5450364_1	886293.Sinac_6595	8.143e-17	91.0	COG1807@1|root,COG3063@1|root,COG1807@2|Bacteria,COG3063@2|Bacteria,2J0A8@203682|Planctomycetes	203682|Planctomycetes	NU	O-linked GlcNAc transferase-putative TPR-containing transmembrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SX3_k127_5457874_0	1521187.JPIM01000194_gene3539	1.12e-14	85.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SX3_k127_5461427_0	404589.Anae109_1169	1.022e-136	459.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,42NAD@68525|delta/epsilon subdivisions,2WKEY@28221|Deltaproteobacteria,2Z1IJ@29|Myxococcales	28221|Deltaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
SX3_k127_5461427_2	234267.Acid_1509	1.359e-24	119.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5461427_1	1408473.JHXO01000008_gene2655	5.407e-124	405.0	COG0330@1|root,COG0330@2|Bacteria,4NH8V@976|Bacteroidetes,2FQPC@200643|Bacteroidia	976|Bacteroidetes	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SX3_k127_5462792_2	1379270.AUXF01000005_gene458	3.464e-12	70.0	COG0845@1|root,COG0845@2|Bacteria,1ZSX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SX3_k127_5462792_0	1379698.RBG1_1C00001G1366	1.575e-85	297.0	COG0577@1|root,COG0577@2|Bacteria,2NQMU@2323|unclassified Bacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SX3_k127_5462792_1	1340493.JNIF01000003_gene4682	4.939e-32	137.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SX3_k127_5462901_0	573413.Spirs_3098	2.195e-106	362.0	COG0535@1|root,COG0535@2|Bacteria,2J83E@203691|Spirochaetes	203691|Spirochaetes	S	PFAM Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SX3_k127_5464365_0	290512.Paes_0461	1.401e-70	261.0	COG1196@1|root,COG1196@2|Bacteria,1FDPC@1090|Chlorobi	1090|Chlorobi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SX3_k127_5484559_1	379066.GAU_0075	5.201e-21	95.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,1ZSMW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SX3_k127_5484559_0	945713.IALB_3155	1.494e-212	669.0	COG2195@1|root,COG2195@2|Bacteria	2|Bacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepT	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
SX3_k127_5484559_2	909663.KI867150_gene2148	6.444e-11	65.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MQ8R@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
SX3_k127_5486673_0	485913.Krac_9431	1.515e-72	261.0	2CI01@1|root,32WPS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5491972_1	706587.Desti_5055	3.292e-08	60.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria	1224|Proteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Dak2,DegV,Radical_SAM
SX3_k127_5491972_0	1047013.AQSP01000126_gene2741	3.342e-264	830.0	COG0339@1|root,COG0339@2|Bacteria,2NP9Q@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M3	prlC	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SX3_k127_5494974_0	1121406.JAEX01000021_gene1463	5.927e-31	132.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,42MX0@68525|delta/epsilon subdivisions,2WM16@28221|Deltaproteobacteria,2M98N@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	PFAM Multi antimicrobial extrusion protein MatE	norM-2	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
SX3_k127_5494974_1	452637.Oter_1459	1.213e-11	71.0	COG0640@1|root,COG0640@2|Bacteria,46WX7@74201|Verrucomicrobia	2|Bacteria	K	PFAM regulatory protein ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SX3_k127_5494974_2	641491.DND132_1675	2.896e-08	62.0	COG2331@1|root,COG2331@2|Bacteria,1NGTT@1224|Proteobacteria,432ZK@68525|delta/epsilon subdivisions,2WXWG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SX3_k127_5503248_0	671143.DAMO_0061	7.757e-116	385.0	COG1206@1|root,COG1206@2|Bacteria,2NS4B@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
SX3_k127_5503677_7	391165.GbCGDNIH1_0700	6.527e-14	74.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2TU5X@28211|Alphaproteobacteria,2JPK0@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
SX3_k127_5503677_4	927658.AJUM01000047_gene2790	2.178e-52	199.0	COG1560@1|root,COG1560@2|Bacteria,4NQEF@976|Bacteroidetes,2FXH7@200643|Bacteroidia	976|Bacteroidetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SX3_k127_5503677_6	1379698.RBG1_1C00001G0548	7.234e-19	94.0	COG3117@1|root,COG3117@2|Bacteria,2NQ8Q@2323|unclassified Bacteria	2|Bacteria	S	Lipopolysaccharide-assembly, LptC-related	lptC	-	-	ko:K09774,ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
SX3_k127_5503677_1	1379698.RBG1_1C00001G0549	2.366e-94	325.0	COG1137@1|root,COG1137@2|Bacteria,2NNRT@2323|unclassified Bacteria	2|Bacteria	S	lipopolysaccharide transport protein B ATP-binding component of ABC superfamily	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1	-	-	ABC_tran,BCA_ABC_TP_C
SX3_k127_5503677_0	861299.J421_3250	7.328e-110	372.0	COG1508@1|root,COG1508@2|Bacteria,1ZT13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-54 factor, Activator interacting domain (AID)	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
SX3_k127_5503677_3	868595.Desca_0774	2.064e-81	282.0	COG0320@1|root,COG0320@2|Bacteria,1TQM4@1239|Firmicutes,2495Q@186801|Clostridia,2619Z@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,LIAS_N,Radical_SAM
SX3_k127_5503677_5	944481.JAFP01000001_gene591	3.036e-23	109.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria,2M6K4@213113|Desulfurellales	28221|Deltaproteobacteria	J	Sigma 54 modulation/S30EA ribosomal protein C terminus	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SX3_k127_5503677_2	1379698.RBG1_1C00001G0553	1.363e-91	311.0	COG1493@1|root,COG1493@2|Bacteria,2NP5B@2323|unclassified Bacteria	2|Bacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
SX3_k127_550593_1	1121396.KB893069_gene1406	7.344e-92	319.0	COG0280@1|root,COG3426@1|root,COG0280@2|Bacteria,COG3426@2|Bacteria,1QTXP@1224|Proteobacteria,42RGR@68525|delta/epsilon subdivisions,2WNWC@28221|Deltaproteobacteria,2MKSE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acetokinase family	-	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase,Cupin_2,PTA_PTB
SX3_k127_550593_2	909663.KI867150_gene2007	1.464e-81	287.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MR82@213462|Syntrophobacterales	28221|Deltaproteobacteria	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SX3_k127_550593_0	1125863.JAFN01000001_gene2044	1.645e-151	491.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
SX3_k127_551533_0	234267.Acid_1905	3.622e-17	94.0	COG3857@1|root,COG3857@2|Bacteria	2|Bacteria	L	exonuclease activity	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
SX3_k127_5515660_3	743836.AYNA01000104_gene2068	4.769e-10	67.0	COG2020@1|root,COG2020@2|Bacteria,1R47K@1224|Proteobacteria,2VG20@28211|Alphaproteobacteria,36ZYY@31993|Methylocystaceae	28211|Alphaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
SX3_k127_5515660_0	1121438.JNJA01000002_gene3716	6.208e-56	201.0	COG0346@1|root,COG0346@2|Bacteria,1RJF9@1224|Proteobacteria,42TD6@68525|delta/epsilon subdivisions,2WP89@28221|Deltaproteobacteria,2MB7M@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SX3_k127_5515660_2	1043493.BBLU01000018_gene1586	2.695e-33	140.0	COG0716@1|root,COG0716@2|Bacteria	2|Bacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Flavodoxin_5
SX3_k127_5515660_1	555079.Toce_0227	6.774e-36	141.0	COG3829@1|root,COG3829@2|Bacteria,1VBSS@1239|Firmicutes	1239|Firmicutes	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5516027_0	330214.NIDE2036	4.828e-125	409.0	COG0272@1|root,COG0272@2|Bacteria,3J0W8@40117|Nitrospirae	40117|Nitrospirae	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SX3_k127_5516027_1	1434325.AZQN01000011_gene3742	4.059e-30	122.0	28N6F@1|root,2ZBBB@2|Bacteria,4NGM1@976|Bacteroidetes,47P0U@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5518810_0	635013.TherJR_2703	3.296e-91	315.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,2613B@186807|Peptococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SX3_k127_5526508_1	1198114.AciX9_3054	2.77e-06	58.0	COG1729@1|root,COG1729@2|Bacteria,3Y4ME@57723|Acidobacteria,2JJA9@204432|Acidobacteriia	204432|Acidobacteriia	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
SX3_k127_5526508_0	234267.Acid_6601	3.5e-27	129.0	COG0265@1|root,COG2203@1|root,COG2208@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria	57723|Acidobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_3,RibD_C,SpoIIE
SX3_k127_5528169_0	1089550.ATTH01000001_gene1532	5.325e-21	103.0	COG1462@1|root,COG1462@2|Bacteria	2|Bacteria	M	curli production assembly transport component CsgG	-	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	CsgG,FlgT_C
SX3_k127_5528169_1	1167006.UWK_02683	1.974e-06	59.0	COG3417@1|root,COG3417@2|Bacteria	2|Bacteria	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)	lpoB	GO:0000270,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0019899,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043085,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	-	ko:K07337,ko:K21008	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	LpoB
SX3_k127_5532273_0	379066.GAU_3915	1.486e-38	152.0	COG1595@1|root,COG1595@2|Bacteria,1ZT2V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SX3_k127_5532273_2	1297617.JPJD01000001_gene2681	0.0001144	53.0	COG5662@1|root,COG5662@2|Bacteria,1VHF3@1239|Firmicutes,24SVU@186801|Clostridia,269PP@186813|unclassified Clostridiales	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SX3_k127_5532273_1	1121904.ARBP01000032_gene2008	5.966e-08	64.0	COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,47NDQ@768503|Cytophagia	976|Bacteroidetes	L	Domain of unknown function (DUF4837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4837
SX3_k127_5535317_1	56780.SYN_00357	4.455e-28	116.0	COG1351@1|root,COG1351@2|Bacteria,1QF4I@1224|Proteobacteria,43A0P@68525|delta/epsilon subdivisions,2X9Q1@28221|Deltaproteobacteria,2MSCD@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Thymidylate synthase complementing protein	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SX3_k127_5535317_0	880073.Calab_1396	2.101e-40	163.0	COG0729@1|root,COG0823@1|root,COG0729@2|Bacteria,COG0823@2|Bacteria,2NRA2@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	treP	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,PD40
SX3_k127_553595_0	525897.Dbac_3486	4.894e-67	244.0	COG1853@1|root,COG1853@2|Bacteria,1RAIQ@1224|Proteobacteria,42RAN@68525|delta/epsilon subdivisions,2WN6G@28221|Deltaproteobacteria,2MGDP@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SX3_k127_553595_1	204669.Acid345_1621	6.076e-17	86.0	COG0845@1|root,COG0845@2|Bacteria,3Y50Z@57723|Acidobacteria,2JMYN@204432|Acidobacteriia	204432|Acidobacteriia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SX3_k127_5536316_0	1047013.AQSP01000105_gene1439	2.984e-62	223.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	MA20_31530	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SX3_k127_5538070_1	1168034.FH5T_14775	1.798e-21	100.0	2EFWM@1|root,339NX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5538070_0	1499967.BAYZ01000089_gene5033	1.185e-54	202.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SX3_k127_5540_0	497964.CfE428DRAFT_4963	1.26e-16	92.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_8
SX3_k127_5545940_0	1341151.ASZU01000015_gene2063	3.57e-21	98.0	COG0640@1|root,COG0640@2|Bacteria,1VEC2@1239|Firmicutes,4I12Q@91061|Bacilli,27C3F@186824|Thermoactinomycetaceae	91061|Bacilli	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
SX3_k127_5559032_0	1499967.BAYZ01000139_gene157	5.356e-163	524.0	COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SX3_k127_5560854_0	379066.GAU_0890	9.059e-57	209.0	COG0098@1|root,COG0098@2|Bacteria,1ZTHD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SX3_k127_5560854_3	518766.Rmar_0860	2.801e-11	67.0	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes	976|Bacteroidetes	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SX3_k127_5560854_1	335543.Sfum_1574	2.409e-36	144.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,42SRC@68525|delta/epsilon subdivisions,2WQQ4@28221|Deltaproteobacteria,2MQJN@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SX3_k127_5560854_2	717231.Flexsi_0483	3.145e-30	121.0	COG0201@1|root,COG0201@2|Bacteria,2GF5J@200930|Deferribacteres	200930|Deferribacteres	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SX3_k127_5567970_1	1121434.AULY01000009_gene1881	2.564e-43	167.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2M9RT@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SX3_k127_5567970_0	1291050.JAGE01000001_gene211	3.692e-53	190.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3WJ07@541000|Ruminococcaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SX3_k127_5567970_2	401526.TcarDRAFT_1438	6.057e-39	147.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4H4B2@909932|Negativicutes	909932|Negativicutes	F	Cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
SX3_k127_5568531_1	857293.CAAU_0665	5.661e-106	349.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,36DSH@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SX3_k127_5568531_0	1125863.JAFN01000001_gene1869	5.612e-153	522.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SX3_k127_5571912_1	1123276.KB893255_gene1852	1.63e-06	60.0	COG1577@1|root,COG4886@1|root,COG4935@1|root,COG1577@2|Bacteria,COG4886@2|Bacteria,COG4935@2|Bacteria,4PPHP@976|Bacteroidetes,47YR0@768503|Cytophagia	976|Bacteroidetes	IO	Putative Ig domain	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,P_proprotein
SX3_k127_5571912_0	546271.Selsp_0543	1.827e-23	104.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,4H28Q@909932|Negativicutes	909932|Negativicutes	C	six-Cys-in-45 modification radical SAM protein	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SX3_k127_5588745_4	555779.Dthio_PD0322	2.942e-12	79.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,42TRE@68525|delta/epsilon subdivisions,2WQBH@28221|Deltaproteobacteria,2MBW5@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SX3_k127_5588745_2	869213.JCM21142_31250	2.145e-38	146.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,47QCA@768503|Cytophagia	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SX3_k127_5588745_0	203119.Cthe_2906	1.832e-122	397.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3WGQK@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SX3_k127_5588745_3	1123371.ATXH01000034_gene793	1.245e-18	95.0	COG0089@1|root,COG0089@2|Bacteria,2GHYR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SX3_k127_5588745_1	498761.HM1_1379	4.732e-42	159.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SX3_k127_5603744_1	391625.PPSIR1_38966	8.203e-06	51.0	COG2006@1|root,COG2006@2|Bacteria,1RK6S@1224|Proteobacteria,42SZ3@68525|delta/epsilon subdivisions,2WP5C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SX3_k127_5603744_0	935836.JAEL01000005_gene2750	1.195e-14	86.0	COG2244@1|root,COG2244@2|Bacteria,1V8VR@1239|Firmicutes,4HNZI@91061|Bacilli,1ZJZ5@1386|Bacillus	91061|Bacilli	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SX3_k127_5631328_0	204669.Acid345_2969	1.733e-176	572.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,3Y3GW@57723|Acidobacteria,2JHKK@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
SX3_k127_5631328_1	713586.KB900536_gene2930	1.881e-08	57.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria	1224|Proteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SX3_k127_5635110_0	1307759.JOMJ01000004_gene2738	3.817e-57	215.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2M7W0@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SX3_k127_5637117_0	292459.STH885	1.488e-32	139.0	COG0500@1|root,COG2226@2|Bacteria,1TR7I@1239|Firmicutes,24FG4@186801|Clostridia	186801|Clostridia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SX3_k127_5645726_3	1336233.JAEH01000001_gene636	1.782e-16	83.0	COG0823@1|root,COG0823@2|Bacteria,1NTH1@1224|Proteobacteria,1SM44@1236|Gammaproteobacteria,2QDET@267890|Shewanellaceae	1236|Gammaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5645726_0	247490.KSU1_C0479	1.337e-286	891.0	COG0488@1|root,COG0488@2|Bacteria,2IWXR@203682|Planctomycetes	203682|Planctomycetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
SX3_k127_5645726_1	316274.Haur_4505	4.812e-25	115.0	COG5624@1|root,COG5624@2|Bacteria,2G94N@200795|Chloroflexi,377N8@32061|Chloroflexia	200795|Chloroflexi	K	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5645726_2	1191523.MROS_2082	5.968e-18	98.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SX3_k127_5645726_5	402880.MmarC5_0829	7.708e-07	62.0	COG3291@1|root,arCOG03396@2157|Archaea	2157|Archaea	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	A2M_comp,CARDB,Prenyltrans,SQHop_cyclase_C,Thiol-ester_cl
SX3_k127_5645726_4	880073.Calab_2402	3.639e-15	89.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5653857_0	1379698.RBG1_1C00001G1502	1.807e-126	416.0	COG2805@1|root,COG2805@2|Bacteria,2NP0T@2323|unclassified Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SX3_k127_5653857_1	556267.HWAG_01227	0.0003215	45.0	29ZJG@1|root,30MJQ@2|Bacteria,1Q1QI@1224|Proteobacteria,42U6T@68525|delta/epsilon subdivisions,2YPWC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5657758_1	1445613.JALM01000019_gene5755	5.437e-41	176.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4E040@85010|Pseudonocardiales	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0033554,GO:0042221,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SX3_k127_5657758_0	1089553.Tph_c09340	1.674e-106	380.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,42EPB@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SX3_k127_565789_2	1191523.MROS_0168	9.045e-36	141.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	yebA	-	-	-	-	-	-	-	-	-	-	-	OapA,Peptidase_M23
SX3_k127_565789_1	944481.JAFP01000001_gene672	2.09e-45	170.0	COG0164@1|root,COG1636@1|root,COG0164@2|Bacteria,COG1636@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2WNK2@28221|Deltaproteobacteria,2M6Q9@213113|Desulfurellales	28221|Deltaproteobacteria	L	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF208,RNase_HII
SX3_k127_565789_0	264732.Moth_1625	1.282e-104	349.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,42ENJ@68295|Thermoanaerobacterales	186801|Clostridia	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SX3_k127_565789_3	1304880.JAGB01000002_gene2418	3.155e-17	83.0	COG2768@1|root,COG2768@2|Bacteria,1VET2@1239|Firmicutes,24QUH@186801|Clostridia	186801|Clostridia	C	Ferredoxin	fdxA	GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114	-	-	-	-	-	-	-	-	-	-	Fer4
SX3_k127_5675808_2	649747.HMPREF0083_05024	3.116e-27	115.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,26RWU@186822|Paenibacillaceae	91061|Bacilli	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SX3_k127_5675808_1	1121440.AUMA01000009_gene553	2.049e-107	361.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2M85X@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SX3_k127_5675808_3	398767.Glov_0666	1.305e-14	87.0	COG1589@1|root,COG1589@2|Bacteria,1RDX7@1224|Proteobacteria,42VCZ@68525|delta/epsilon subdivisions,2WRVM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Essential cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SX3_k127_5675808_0	573370.DMR_33260	1.629e-111	370.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2M8HY@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SX3_k127_5683486_0	768706.Desor_5367	7.309e-08	63.0	2DMAW@1|root,32EM1@2|Bacteria,1UPNC@1239|Firmicutes,25HJQ@186801|Clostridia,2627W@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5683486_1	467200.ACFA01000441_gene1976	8.721e-06	57.0	COG5555@1|root,COG5555@2|Bacteria,2GKZ9@201174|Actinobacteria	201174|Actinobacteria	N	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
SX3_k127_5684099_1	344747.PM8797T_19612	4.405e-40	164.0	COG0726@1|root,COG0726@2|Bacteria,2J0S7@203682|Planctomycetes	203682|Planctomycetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SX3_k127_5684099_0	497964.CfE428DRAFT_2188	3.541e-81	293.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SX3_k127_569246_1	589865.DaAHT2_0278	1.103e-43	165.0	COG0622@1|root,COG0622@2|Bacteria,1RCUQ@1224|Proteobacteria,43B45@68525|delta/epsilon subdivisions,2WR60@28221|Deltaproteobacteria,2MKR6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM phosphodiesterase, MJ0936 family	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SX3_k127_569246_0	237368.SCABRO_00251	1.179e-73	258.0	COG0524@1|root,COG0524@2|Bacteria,2IX8I@203682|Planctomycetes	203682|Planctomycetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SX3_k127_5693856_1	338966.Ppro_2818	1.369e-25	120.0	2CEWP@1|root,33R6D@2|Bacteria,1NT52@1224|Proteobacteria,42Y56@68525|delta/epsilon subdivisions,2WUQX@28221|Deltaproteobacteria,43TA6@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5693856_2	269799.Gmet_0755	5.648e-06	56.0	COG2888@1|root,COG2888@2|Bacteria	2|Bacteria	J	peptidyl-tyrosine sulfation	ybeL	-	1.17.4.1,4.6.1.1	ko:K00525,ko:K01768	ko00230,ko00240,ko01100,ko02025,ko04113,ko04213,map00230,map00240,map01100,map02025,map04113,map04213	M00053,M00695	R00089,R00434,R02017,R02018,R02019,R02024	RC00295,RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	DUF1451
SX3_k127_5693856_0	269799.Gmet_0754	1.674e-119	398.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,42P7D@68525|delta/epsilon subdivisions,2WJ6S@28221|Deltaproteobacteria,43UZT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,DZR,SHOCT,zinc_ribbon_2
SX3_k127_570082_0	765913.ThidrDRAFT_0520	8.991e-11	74.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WX66@135613|Chromatiales	135613|Chromatiales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SX3_k127_5701490_0	880073.Calab_3299	2.665e-09	65.0	COG2067@1|root,COG2067@2|Bacteria,2NRA4@2323|unclassified Bacteria	2|Bacteria	I	PFAM Uncharacterised protein family (UPF0164)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
SX3_k127_5701490_1	1379698.RBG1_1C00001G0583	1.756e-07	65.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cohesin,FlgD_ig,Peptidase_S74
SX3_k127_5710527_2	1121422.AUMW01000009_gene3352	3.194e-19	89.0	COG0425@1|root,COG0425@2|Bacteria,1UWPI@1239|Firmicutes,25HWP@186801|Clostridia,265U8@186807|Peptococcaceae	186801|Clostridia	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
SX3_k127_5710527_0	121759.XP_010756353.1	4.221e-136	447.0	COG0520@1|root,KOG2142@2759|Eukaryota,38F30@33154|Opisthokonta,3NY5Z@4751|Fungi,3QREF@4890|Ascomycota,20FDX@147545|Eurotiomycetes,3B2AK@33183|Onygenales,3FQBE@34383|Onygenales incertae sedis	4751|Fungi	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SX3_k127_5710527_1	693661.Arcve_0284	5.868e-40	155.0	COG0477@1|root,arCOG00130@2157|Archaea,2XVR7@28890|Euryarchaeota,245V0@183980|Archaeoglobi	183980|Archaeoglobi	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SX3_k127_5714938_1	1163408.UU9_04202	4.773e-44	168.0	COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,1RN4M@1236|Gammaproteobacteria,1X5SH@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SX3_k127_5714938_3	75379.Tint_1509	5.794e-27	125.0	COG0726@1|root,COG0726@2|Bacteria,1N53V@1224|Proteobacteria,2VWYF@28216|Betaproteobacteria,1KMQR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SX3_k127_5714938_2	1232410.KI421415_gene3082	1.949e-34	134.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Smr protein MutS2	-	-	-	-	-	-	-	-	-	-	-	-	Smr
SX3_k127_5714938_0	243231.GSU2429	8.292e-50	191.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria,43SP4@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	SurA N-terminal domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SX3_k127_5714938_4	1249627.D779_1986	3.498e-12	78.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,1S24U@1236|Gammaproteobacteria,1X2FK@135613|Chromatiales	135613|Chromatiales	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SX3_k127_5714938_5	768704.Desmer_3328	9.78e-05	54.0	COG4219@1|root,COG4219@2|Bacteria,1V7ER@1239|Firmicutes,24JSF@186801|Clostridia,26254@186807|Peptococcaceae	186801|Clostridia	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_572201_1	1089547.KB913013_gene717	5.857e-06	60.0	COG2866@1|root,COG3055@1|root,COG4733@1|root,COG2866@2|Bacteria,COG3055@2|Bacteria,COG4733@2|Bacteria,4NH4I@976|Bacteroidetes,47MEA@768503|Cytophagia	976|Bacteroidetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SX3_k127_572201_0	29176.XP_003882643.1	7.864e-09	70.0	2CYGN@1|root,2S4A2@2759|Eukaryota,3Y9P1@5794|Apicomplexa	5794|Apicomplexa	S	containing protein	-	GO:0003008,GO:0003674,GO:0005488,GO:0005518,GO:0005575,GO:0005576,GO:0007600,GO:0007605,GO:0008150,GO:0008360,GO:0022603,GO:0022604,GO:0031012,GO:0032501,GO:0044421,GO:0044877,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050954,GO:0051128,GO:0065007,GO:0065008	-	-	-	-	-	-	-	-	-	-	COLFI,F5_F8_type_C,LCCL,Ricin_B_lectin
SX3_k127_5722186_2	425104.Ssed_1747	0.0002017	51.0	COG0366@1|root,COG1409@1|root,COG0366@2|Bacteria,COG1409@2|Bacteria,1PKTM@1224|Proteobacteria,1RWFT@1236|Gammaproteobacteria,2QDDA@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Metallophos,Pur_ac_phosph_N
SX3_k127_5722186_1	639283.Snov_0436	7.898e-07	56.0	COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,2TSIN@28211|Alphaproteobacteria,3EZ0D@335928|Xanthobacteraceae	28211|Alphaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SX3_k127_5722186_0	1223521.BBJX01000001_gene1038	1.755e-12	79.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,4ADC0@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SX3_k127_572229_0	1121930.AQXG01000007_gene511	1.198e-95	322.0	COG0745@1|root,COG0745@2|Bacteria,4PM6N@976|Bacteroidetes,1J10G@117747|Sphingobacteriia	976|Bacteroidetes	KT	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
SX3_k127_572229_1	518766.Rmar_1450	1.949e-83	288.0	COG0642@1|root,COG2205@2|Bacteria,4PKGE@976|Bacteroidetes,1FIRF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SX3_k127_572959_0	443255.SCLAV_4434	1.481e-19	100.0	COG2133@1|root,COG2133@2|Bacteria,2GISM@201174|Actinobacteria	201174|Actinobacteria	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SX3_k127_5746589_0	1121285.AUFK01000010_gene1724	7.745e-17	93.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1HYN2@117743|Flavobacteriia,3ZQNW@59732|Chryseobacterium	976|Bacteroidetes	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
SX3_k127_5749063_0	861299.J421_3245	2.265e-93	321.0	COG0463@1|root,COG0463@2|Bacteria,1ZT31@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SX3_k127_5749063_1	517417.Cpar_0163	2.189e-32	142.0	COG4485@1|root,COG4485@2|Bacteria,1FFQB@1090|Chlorobi	1090|Chlorobi	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5753616_1	1379698.RBG1_1C00001G1364	9.91e-68	244.0	COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
SX3_k127_5753616_0	517418.Ctha_0586	3.091e-95	316.0	COG1136@1|root,COG1136@2|Bacteria,1FDKJ@1090|Chlorobi	1090|Chlorobi	P	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SX3_k127_575397_1	946483.Cenrod_2149	2.1e-21	96.0	COG0425@1|root,COG0425@2|Bacteria,1P4MT@1224|Proteobacteria	1224|Proteobacteria	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
SX3_k127_575397_0	767817.Desgi_1166	2.631e-183	583.0	COG3259@1|root,COG3259@2|Bacteria,1UZNV@1239|Firmicutes,24F0H@186801|Clostridia,2644W@186807|Peptococcaceae	186801|Clostridia	C	Nickel-dependent hydrogenase	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
SX3_k127_5767161_2	592015.HMPREF1705_01395	1.139e-17	85.0	COG0209@1|root,COG0209@2|Bacteria,3TAE6@508458|Synergistetes	508458|Synergistetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
SX3_k127_5767161_0	1382306.JNIM01000001_gene897	3.916e-46	183.0	COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SX3_k127_5767161_3	1174528.JH992898_gene3125	7.041e-06	56.0	COG1246@1|root,COG1246@2|Bacteria,1G5ND@1117|Cyanobacteria,1JIPI@1189|Stigonemataceae	1117|Cyanobacteria	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SX3_k127_5767161_1	338963.Pcar_2073	1.726e-18	86.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria,43SPT@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
SX3_k127_5775752_0	1430331.EP10_03880	3.599e-13	79.0	COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,1WFNJ@129337|Geobacillus	91061|Bacilli	F	Belongs to the 5'-nucleotidase family	yunD	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
SX3_k127_5786456_0	338966.Ppro_1666	9.224e-203	647.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WIX6@28221|Deltaproteobacteria,43TEK@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA-1	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
SX3_k127_5786456_1	398767.Glov_1857	2.5e-29	118.0	COG1014@1|root,COG1014@2|Bacteria,1RH9B@1224|Proteobacteria,42SK4@68525|delta/epsilon subdivisions,2WPI8@28221|Deltaproteobacteria,43TA9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	iorB-1	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
SX3_k127_5790413_2	1268303.RHODMAR_2537	8.426e-10	60.0	COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria,4G1IZ@85025|Nocardiaceae	201174|Actinobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SX3_k127_5790413_0	891968.Anamo_0432	6.447e-62	226.0	COG0568@1|root,COG0568@2|Bacteria,3TACS@508458|Synergistetes	508458|Synergistetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SX3_k127_5790413_1	344747.PM8797T_06792	1.038e-13	83.0	COG0503@1|root,COG0503@2|Bacteria,2IZ9H@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SX3_k127_5794997_1	1121396.KB892990_gene4470	2.264e-22	102.0	COG0697@1|root,COG0697@2|Bacteria,1Q9JX@1224|Proteobacteria,434FQ@68525|delta/epsilon subdivisions,2WYT5@28221|Deltaproteobacteria,2MN71@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SX3_k127_5794997_0	1254432.SCE1572_49530	1.062e-87	304.0	COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,437F6@68525|delta/epsilon subdivisions,2X2MS@28221|Deltaproteobacteria,2YTV3@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
SX3_k127_5815278_1	880073.Calab_0112	5.474e-09	68.0	COG4775@1|root,COG4775@2|Bacteria,2NPNI@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SX3_k127_5815278_0	880073.Calab_3754	1.92e-51	209.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5815520_1	404380.Gbem_3603	9.415e-10	69.0	COG1729@1|root,COG1729@2|Bacteria,1RGD4@1224|Proteobacteria,42S9U@68525|delta/epsilon subdivisions,2WP0U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,YfiO
SX3_k127_5815520_0	469616.FMAG_02432	1.465e-10	68.0	COG0759@1|root,COG0759@2|Bacteria,37AZG@32066|Fusobacteria	32066|Fusobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SX3_k127_5817586_0	375286.mma_2544	1.078e-124	410.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,2VK6T@28216|Betaproteobacteria,473E7@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity	aqpZ	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SX3_k127_5817586_2	509191.AEDB02000084_gene5166	1.284e-05	57.0	COG1680@1|root,COG1680@2|Bacteria,1TRR5@1239|Firmicutes,249KP@186801|Clostridia,3WKA3@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase,Cu_amine_oxidN1,DUF3471
SX3_k127_5834381_0	1379698.RBG1_1C00001G1656	9.493e-320	1000.0	COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SX3_k127_5834381_1	926567.TheveDRAFT_1028	1.236e-34	147.0	COG1520@1|root,COG1520@2|Bacteria,3TB0M@508458|Synergistetes	508458|Synergistetes	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
SX3_k127_5871612_2	1232666.JANE01000014_gene1790	4.562e-17	88.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,4GXMR@90964|Staphylococcaceae	91061|Bacilli	S	COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SX3_k127_5871612_0	1379270.AUXF01000004_gene3060	2.935e-97	332.0	COG3367@1|root,COG3367@2|Bacteria,1ZUM9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
SX3_k127_5871612_1	378806.STAUR_2793	4.545e-33	147.0	COG1468@1|root,COG1468@2|Bacteria	2|Bacteria	L	DNA catabolic process, exonucleolytic	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779,PDDEXK_1
SX3_k127_5871612_3	479432.Sros_1139	2.196e-05	47.0	COG0736@1|root,COG0736@2|Bacteria,2IQF6@201174|Actinobacteria,4EK7U@85012|Streptosporangiales	201174|Actinobacteria	I	4'-phosphopantetheinyl transferase superfamily	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SX3_k127_5878361_0	1379698.RBG1_1C00001G0709	4.245e-74	257.0	COG1899@1|root,COG1899@2|Bacteria,2NR8I@2323|unclassified Bacteria	2|Bacteria	O	Deoxyhypusine synthase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
SX3_k127_5878361_1	1232437.KL662043_gene2223	8.193e-47	179.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,42NBC@68525|delta/epsilon subdivisions,2WIMR@28221|Deltaproteobacteria,2MIAP@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SX3_k127_5905631_0	880073.Calab_1111	4.406e-103	357.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SX3_k127_5905631_1	1288963.ADIS_3639	9.539e-31	137.0	COG2244@1|root,COG2244@2|Bacteria,4NGVA@976|Bacteroidetes,47PAZ@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SX3_k127_5916983_1	1444309.JAQG01000106_gene1082	1.359e-45	190.0	COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,26T6Z@186822|Paenibacillaceae	91061|Bacilli	L	helicase involved in DNA repair and perhaps also replication	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2,RNase_T,ResIII
SX3_k127_5916983_0	1123373.ATXI01000006_gene189	2.205e-142	465.0	COG0422@1|root,COG0422@2|Bacteria,2GGW7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
SX3_k127_5916983_2	1519464.HY22_11245	1.142e-16	83.0	COG4775@1|root,COG4775@2|Bacteria,1FEGD@1090|Chlorobi	1090|Chlorobi	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
SX3_k127_5927160_1	28229.ND2E_3292	3.789e-13	74.0	COG3104@1|root,COG3104@2|Bacteria,1R5E8@1224|Proteobacteria,1RQR0@1236|Gammaproteobacteria,2Q6F7@267889|Colwelliaceae	1236|Gammaproteobacteria	E	POT family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SX3_k127_5927160_0	1340493.JNIF01000004_gene294	7.176e-116	392.0	COG0591@1|root,COG0591@2|Bacteria,3Y4WN@57723|Acidobacteria	57723|Acidobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SX3_k127_5928547_1	1121920.AUAU01000030_gene2723	2.02e-48	176.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SX3_k127_5928547_0	644968.DFW101_2752	4.04e-172	548.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,42N15@68525|delta/epsilon subdivisions,2WJ0Y@28221|Deltaproteobacteria,2M82I@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SX3_k127_5935135_1	338963.Pcar_2483	4.316e-46	169.0	COG0730@1|root,COG0730@2|Bacteria,1PD7F@1224|Proteobacteria,42TC8@68525|delta/epsilon subdivisions,2WPFJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SX3_k127_5935135_0	215803.DB30_4900	2.896e-105	361.0	COG1680@1|root,COG1680@2|Bacteria,1PEI7@1224|Proteobacteria,43DSW@68525|delta/epsilon subdivisions,2X8V3@28221|Deltaproteobacteria,2Z0DE@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SX3_k127_5939187_1	1499967.BAYZ01000156_gene556	6.091e-24	112.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568,ko:K20444	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SX3_k127_5939187_0	1499967.BAYZ01000069_gene1853	9.573e-186	590.0	COG0474@1|root,COG0474@2|Bacteria,2NNSC@2323|unclassified Bacteria	2|Bacteria	P	Cation transporter/ATPase, N-terminus	pacL	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SX3_k127_5945773_0	555779.Dthio_PD2268	4.229e-99	336.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42QFH@68525|delta/epsilon subdivisions,2WKWR@28221|Deltaproteobacteria,2M7U5@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Glycos_transf_2,Radical_SAM
SX3_k127_5945773_1	742740.HMPREF9474_03617	5.402e-83	289.0	COG2515@1|root,COG2515@2|Bacteria,1UDCW@1239|Firmicutes,24BXZ@186801|Clostridia,220EC@1506553|Lachnoclostridium	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
SX3_k127_595790_0	1408473.JHXO01000005_gene1865	2.396e-37	149.0	COG0484@1|root,COG0484@2|Bacteria,4NPS0@976|Bacteroidetes,2FXKU@200643|Bacteroidia	976|Bacteroidetes	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_5965468_0	768679.TTX_1889	1.473e-26	116.0	COG0148@1|root,arCOG01169@2157|Archaea,2XPZ6@28889|Crenarchaeota	28889|Crenarchaeota	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SX3_k127_5965468_1	420246.GTNG_1326	1.161e-18	94.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,1WEA6@129337|Geobacillus	91061|Bacilli	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SX3_k127_5969803_0	203275.BFO_0431	2.35e-14	85.0	COG1305@1|root,COG1305@2|Bacteria,4NIJF@976|Bacteroidetes,2FQJU@200643|Bacteroidia,22XJ6@171551|Porphyromonadaceae	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3858)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
SX3_k127_5971960_0	1110502.TMO_2380	3.84e-07	58.0	COG5005@1|root,COG5005@2|Bacteria,1N6UC@1224|Proteobacteria,2UDKF@28211|Alphaproteobacteria,2JUND@204441|Rhodospirillales	204441|Rhodospirillales	S	Phage virion morphogenesis family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_tail_S
SX3_k127_5972967_0	1336233.JAEH01000014_gene3565	2.605e-06	59.0	COG3595@1|root,COG3595@2|Bacteria,1RI1P@1224|Proteobacteria,1RRZW@1236|Gammaproteobacteria,2QB2H@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SX3_k127_5972967_1	1382305.AZUC01000009_gene1891	2.505e-05	56.0	COG3595@1|root,COG3595@2|Bacteria,1TS90@1239|Firmicutes,4HDI6@91061|Bacilli,26CW6@186818|Planococcaceae	91061|Bacilli	S	Putative adhesin	yvlB	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SX3_k127_5983646_0	1121859.KB890754_gene1026	4.221e-79	283.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF70@976|Bacteroidetes,47JEZ@768503|Cytophagia	976|Bacteroidetes	EU	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
SX3_k127_5983646_1	517418.Ctha_0172	9.518e-33	129.0	COG1765@1|root,COG1765@2|Bacteria,1FE41@1090|Chlorobi	1090|Chlorobi	O	PFAM OsmC family protein	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC
SX3_k127_600477_1	1379698.RBG1_1C00001G0634	1.474e-38	149.0	COG1051@1|root,COG1051@2|Bacteria,2NPZ5@2323|unclassified Bacteria	2|Bacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
SX3_k127_600477_0	351160.RCIX757	8.779e-41	161.0	COG0652@1|root,arCOG04767@2157|Archaea,2XTHC@28890|Euryarchaeota,2NASJ@224756|Methanomicrobia	224756|Methanomicrobia	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SX3_k127_6011510_0	632518.Calow_0751	1.272e-57	204.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,42FGH@68295|Thermoanaerobacterales	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SX3_k127_6011510_1	1423758.BN55_03610	2.652e-26	113.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,3F6VV@33958|Lactobacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SX3_k127_6011510_2	555779.Dthio_PD1343	1.178e-12	71.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2MCGN@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SX3_k127_6013606_1	880073.Calab_3589	6.837e-37	143.0	COG1386@1|root,COG1386@2|Bacteria,2NPPM@2323|unclassified Bacteria	2|Bacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SX3_k127_6013606_0	760568.Desku_1862	7.732e-57	207.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,261JB@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SX3_k127_6013606_2	1123371.ATXH01000002_gene335	5.217e-31	127.0	COG0079@1|root,COG0079@2|Bacteria,2GGZI@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SX3_k127_6015602_1	1379698.RBG1_1C00001G1139	1.077e-44	168.0	COG0323@1|root,COG0323@2|Bacteria,2NNP7@2323|unclassified Bacteria	2|Bacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
SX3_k127_6015602_0	349124.Hhal_0667	1.239e-47	180.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1WWI0@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SX3_k127_6029548_0	1265505.ATUG01000001_gene3682	1.251e-55	203.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2MI58@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SX3_k127_6038872_1	330214.NIDE0819	5.845e-11	66.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	omp-1X	-	-	ko:K12976,ko:K22110	-	-	-	-	ko00000,ko01000,ko01005,ko02000	1.B.35.1,1.B.35.2	-	-	DUF2490,OMP_b-brl,Surface_Ag_2
SX3_k127_6038872_0	530564.Psta_3944	5.344e-91	313.0	COG1858@1|root,COG1858@2|Bacteria,2IY7G@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
SX3_k127_6041101_0	880073.Calab_0921	1.7e-20	106.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
SX3_k127_6047165_1	926554.KI912671_gene374	1.639e-31	136.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SX3_k127_6047165_0	945713.IALB_0428	2.032e-35	137.0	COG1187@1|root,COG1187@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rluE	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
SX3_k127_6066159_1	1125863.JAFN01000001_gene1724	1.672e-43	166.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
SX3_k127_6066159_0	1125863.JAFN01000001_gene1723	7.942e-140	456.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the EPSP synthase family. MurA subfamily	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SX3_k127_6079664_4	1232437.KL661981_gene3734	2.747e-16	84.0	2DE97@1|root,2ZM1M@2|Bacteria	2|Bacteria	S	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
SX3_k127_6079664_1	1379698.RBG1_1C00001G0518	1.006e-122	425.0	COG0515@1|root,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
SX3_k127_6079664_2	1230457.C476_15590	4.525e-44	179.0	COG0367@1|root,arCOG00121@2157|Archaea,2XVTD@28890|Euryarchaeota,23TT1@183963|Halobacteria	183963|Halobacteria	E	COG0367 Asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SX3_k127_6079664_3	1202768.JROF01000033_gene2003	2.024e-42	165.0	COG0367@1|root,arCOG00121@2157|Archaea,2XVTD@28890|Euryarchaeota,23TT1@183963|Halobacteria	183963|Halobacteria	E	COG0367 Asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SX3_k127_6079664_0	1121920.AUAU01000012_gene2697	1.64e-137	443.0	COG4690@1|root,COG4690@2|Bacteria,3Y8TZ@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
SX3_k127_6080657_2	1131269.AQVV01000007_gene1040	0.0007406	50.0	COG0457@1|root,COG0457@2|Bacteria	1131269.AQVV01000007_gene1040|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_6080657_0	575589.HMPREF0018_02531	2.155e-15	78.0	COG2155@1|root,COG2155@2|Bacteria,1N77I@1224|Proteobacteria,1SHMF@1236|Gammaproteobacteria,3NPGK@468|Moraxellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
SX3_k127_6080657_1	945713.IALB_0016	0.0001785	51.0	2EGEF@1|root,33A6F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_609100_1	517418.Ctha_2165	2.018e-28	121.0	COG2067@1|root,COG2067@2|Bacteria,1FEW1@1090|Chlorobi	1090|Chlorobi	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_609100_0	984262.SGRA_3014	9.803e-66	250.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1IW9T@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
SX3_k127_609447_0	266779.Meso_2373	6.692e-53	198.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TVAX@28211|Alphaproteobacteria,43PSD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SX3_k127_609447_1	1333998.M2A_2669	4.909e-07	56.0	COG2244@1|root,COG2244@2|Bacteria,1NCIA@1224|Proteobacteria	1224|Proteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SX3_k127_6105310_3	629773.AORY01000004_gene574	1.721e-14	79.0	COG3682@1|root,COG3682@2|Bacteria,1RH6Y@1224|Proteobacteria,2UD0F@28211|Alphaproteobacteria,2KE4P@204457|Sphingomonadales	204457|Sphingomonadales	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SX3_k127_6105310_2	96561.Dole_2043	5.528e-15	87.0	COG1800@1|root,COG2885@1|root,COG3420@1|root,COG1800@2|Bacteria,COG2885@2|Bacteria,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_6105310_1	1121920.AUAU01000033_gene2767	4.335e-22	105.0	COG2197@1|root,COG2197@2|Bacteria,3Y4DR@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SX3_k127_6105310_4	269800.Tfu_2277	2.611e-12	79.0	COG4585@1|root,COG4585@2|Bacteria,2GMAB@201174|Actinobacteria,4ENFP@85012|Streptosporangiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SX3_k127_6105310_0	1307759.JOMJ01000003_gene1519	6.838e-28	117.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,42PZB@68525|delta/epsilon subdivisions,2WK77@28221|Deltaproteobacteria,2M8Z1@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM glycoside hydrolase family 77	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SX3_k127_6109238_1	525903.Taci_0648	5.237e-91	308.0	COG0018@1|root,COG0018@2|Bacteria,3TA5K@508458|Synergistetes	508458|Synergistetes	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SX3_k127_6109238_0	1144275.COCOR_04284	8.951e-95	321.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,2YU0F@29|Myxococcales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
SX3_k127_6109238_2	765914.ThisiDRAFT_0680	5.096e-06	55.0	COG4970@1|root,COG4970@2|Bacteria,1NBWI@1224|Proteobacteria,1S5MN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	general secretion pathway protein	xpsH	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
SX3_k127_6111200_0	85643.Tmz1t_1473	1.088e-176	580.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,2KUW0@206389|Rhodocyclales	206389|Rhodocyclales	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
SX3_k127_6111200_1	1047013.AQSP01000097_gene1950	6.34e-65	225.0	COG0205@1|root,COG0205@2|Bacteria,2NNY2@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-3	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SX3_k127_6126290_1	340177.Cag_0986	2.418e-06	57.0	COG1538@1|root,COG1538@2|Bacteria,1FDGZ@1090|Chlorobi	1090|Chlorobi	MU	PFAM outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
SX3_k127_6126290_0	335543.Sfum_3122	9.469e-10	65.0	2EPAA@1|root,33GX1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_6131345_5	592015.HMPREF1705_00830	7.117e-07	61.0	COG1527@1|root,COG1527@2|Bacteria,3T9UA@508458|Synergistetes	508458|Synergistetes	C	PFAM H transporting two-sector ATPase C (AC39) subunit	-	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
SX3_k127_6131345_4	877414.ATWA01000004_gene521	3.831e-15	83.0	COG1390@1|root,COG1390@2|Bacteria,1VEEA@1239|Firmicutes,24QMH@186801|Clostridia,2695Z@186813|unclassified Clostridiales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
SX3_k127_6131345_3	568816.Acin_0182	4.323e-43	162.0	COG0636@1|root,COG0636@2|Bacteria,1V786@1239|Firmicutes	1239|Firmicutes	C	Belongs to the V-ATPase proteolipid subunit family	ntpK	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
SX3_k127_6131345_2	555088.DealDRAFT_1684	1.907e-80	293.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia	186801|Clostridia	C	Belongs to the V-ATPase 116 kDa subunit family	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
SX3_k127_6131345_1	1125863.JAFN01000001_gene592	5.078e-103	355.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42TDH@68525|delta/epsilon subdivisions,2WIQT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SX3_k127_6131345_0	867903.ThesuDRAFT_02282	2.464e-118	387.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SX3_k127_613256_0	1123267.JONN01000001_gene1238	6.427e-211	691.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,MRJP
SX3_k127_613256_1	1123267.JONN01000001_gene1239	2.663e-20	98.0	2C1YS@1|root,2ZD2Y@2|Bacteria	2|Bacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SX3_k127_6135265_0	237368.SCABRO_02223	9.981e-145	470.0	COG0714@1|root,COG0714@2|Bacteria,2IX23@203682|Planctomycetes	203682|Planctomycetes	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SX3_k127_6135265_1	237368.SCABRO_01880	4.192e-102	338.0	COG1721@1|root,COG1721@2|Bacteria,2IXT7@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SX3_k127_6137435_2	1124780.ANNU01000008_gene2701	4.815e-16	81.0	COG1656@1|root,COG1656@2|Bacteria,4NMYZ@976|Bacteroidetes,47QXF@768503|Cytophagia	976|Bacteroidetes	S	Mut7-C ubiquitin	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
SX3_k127_6137435_1	643867.Ftrac_1443	2.072e-16	91.0	COG3637@1|root,COG3637@2|Bacteria,4NRJW@976|Bacteroidetes,47PGW@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
SX3_k127_6137435_0	880073.Calab_1878	6.436e-149	511.0	2CD20@1|root,2Z7SQ@2|Bacteria,2NNUF@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_6137435_4	349741.Amuc_0610	3.161e-05	57.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,46SYU@74201|Verrucomicrobia,2IUQE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Outer membrane lipoprotein	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_6,YfiO
SX3_k127_6137435_3	945713.IALB_0415	1.595e-15	85.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_6140885_1	941449.dsx2_1551	6.224e-14	78.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2M7W0@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SX3_k127_6140885_0	96561.Dole_2056	2.654e-18	89.0	COG0227@1|root,COG0227@2|Bacteria,1PTFN@1224|Proteobacteria,42V1S@68525|delta/epsilon subdivisions,2WR85@28221|Deltaproteobacteria,2MKZY@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SX3_k127_6140885_2	381764.Fnod_1019	3.295e-10	63.0	COG1200@1|root,COG1200@2|Bacteria,2GBZ9@200918|Thermotogae	200918|Thermotogae	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_N,RecG_wedge
SX3_k127_6146372_0	1415780.JPOG01000001_gene2317	9.106e-68	241.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1X43Q@135614|Xanthomonadales	135614|Xanthomonadales	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SX3_k127_6146372_1	1304275.C41B8_13495	1.282e-52	188.0	COG3439@1|root,COG3439@2|Bacteria,1RHJQ@1224|Proteobacteria,1S5ZG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
SX3_k127_6148320_2	1517682.HW49_01065	5.574e-11	72.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,2FMRS@200643|Bacteroidia,22WWU@171551|Porphyromonadaceae	976|Bacteroidetes	E	Tryptophanase	tpl	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase
SX3_k127_6148320_0	398512.JQKC01000003_gene5074	1.94e-107	357.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WGS4@541000|Ruminococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SX3_k127_6148320_1	1313301.AUGC01000012_gene1308	3.357e-70	244.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
SX3_k127_6150764_1	1173029.JH980292_gene2288	1.289e-12	73.0	COG0457@1|root,COG0457@2|Bacteria,1GD9N@1117|Cyanobacteria,1HH3D@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SX3_k127_6150764_0	1121920.AUAU01000004_gene786	5.522e-48	180.0	COG0631@1|root,COG0631@2|Bacteria,3Y4SV@57723|Acidobacteria	57723|Acidobacteria	T	protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SX3_k127_616732_1	880073.Calab_3215	3.367e-21	99.0	COG0366@1|root,COG0708@1|root,COG0366@2|Bacteria,COG0708@2|Bacteria,2NREA@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 70	-	-	3.1.11.2,3.2.1.1	ko:K01142,ko:K01176	ko00500,ko01100,ko03410,ko04973,map00500,map01100,map03410,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000,ko03400	-	GH13	-	Alpha-amylase,CBM_25,DUF1939,He_PIG
SX3_k127_616732_0	1131269.AQVV01000040_gene1641	5.226e-26	113.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SX3_k127_6170673_1	290397.Adeh_1018	6.541e-09	62.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SX3_k127_6170673_0	555079.Toce_0326	9.297e-15	77.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,42FBV@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
SX3_k127_6175052_1	1449126.JQKL01000002_gene1550	0.0001846	54.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD
SX3_k127_6175052_0	1121423.JONT01000007_gene534	7.292e-40	166.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,26166@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_20,Fer4_6,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Pyr_redox_2,Pyr_redox_3
SX3_k127_6185769_0	338966.Ppro_0427	5.926e-68	241.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,43STZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
SX3_k127_6185769_1	880073.Calab_2084	6.991e-08	61.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C,FlgD_ig,Peptidase_S74
SX3_k127_6185769_2	635013.TherJR_0779	1.732e-07	60.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.1.3.6,3.1.4.16	ko:K01119,ko:K20276	ko00230,ko00240,ko02024,map00230,map00240,map02024	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	CarboxypepD_reg,Peptidase_S8,SLH
SX3_k127_6186151_2	65093.PCC7418_0889	5.397e-77	267.0	COG2905@1|root,COG2905@2|Bacteria,1GPZ1@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
SX3_k127_6186151_1	909663.KI867150_gene2668	4.097e-122	403.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria,2MQ6W@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SX3_k127_6186151_0	909663.KI867150_gene2669	6.461e-226	707.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2WJEA@28221|Deltaproteobacteria,2MQ6G@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
SX3_k127_6191641_2	459349.CLOAM0243	4.312e-23	114.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SX3_k127_6191641_0	1278073.MYSTI_02059	1.789e-283	917.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SX3_k127_6191641_1	1378168.N510_02869	6.439e-43	163.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes	1239|Firmicutes	M	Cell wall formation	murB	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SX3_k127_6193464_0	1047013.AQSP01000141_gene115	3.584e-159	516.0	COG3104@1|root,COG3104@2|Bacteria,2NQCQ@2323|unclassified Bacteria	2|Bacteria	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SX3_k127_620698_0	880072.Desac_2078	2.545e-35	150.0	COG4775@1|root,COG4775@2|Bacteria,1QX52@1224|Proteobacteria,43CEZ@68525|delta/epsilon subdivisions,2X7PY@28221|Deltaproteobacteria,2MRBQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SX3_k127_6208580_0	639282.DEFDS_1228	3.521e-225	706.0	COG4799@1|root,COG4799@2|Bacteria,2GEP0@200930|Deferribacteres	200930|Deferribacteres	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SX3_k127_6208580_1	273068.TTE1217	1.04e-214	680.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,42FIA@68295|Thermoanaerobacterales	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SX3_k127_6208580_3	203275.BFO_0966	3.094e-33	139.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,2FRZS@200643|Bacteroidia,22XX8@171551|Porphyromonadaceae	976|Bacteroidetes	E	methylmalonyl-CoA epimerase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SX3_k127_6208580_2	247490.KSU1_C0203	3.853e-129	423.0	COG0598@1|root,COG0598@2|Bacteria,2IX61@203682|Planctomycetes	203682|Planctomycetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SX3_k127_6208580_4	998674.ATTE01000001_gene3216	2.71e-10	60.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RY2T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SX3_k127_6208633_0	247490.KSU1_D0082	3.429e-97	334.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	wzx	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SX3_k127_6208633_1	314285.KT71_02737	6.891e-07	57.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RQGN@1236|Gammaproteobacteria,1J9KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SX3_k127_6233608_1	383372.Rcas_4336	1.792e-42	158.0	COG0138@1|root,COG0138@2|Bacteria,2G5JG@200795|Chloroflexi,3751F@32061|Chloroflexia	32061|Chloroflexia	F	TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SX3_k127_6233608_0	648996.Theam_0171	2.972e-84	290.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2G3NT@200783|Aquificae	200783|Aquificae	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SX3_k127_6233625_1	1120948.KB903218_gene1782	4.491e-09	63.0	COG0673@1|root,COG0673@2|Bacteria,2HEK5@201174|Actinobacteria,4E0B8@85010|Pseudonocardiales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SX3_k127_6233625_0	864069.MicloDRAFT_00035310	3.462e-22	104.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2UBTC@28211|Alphaproteobacteria,1JVPX@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
SX3_k127_6233888_0	932678.THERU_03085	1.056e-10	73.0	COG1333@1|root,COG1333@2|Bacteria,2G400@200783|Aquificae	200783|Aquificae	O	ResB family	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
SX3_k127_6235172_2	1304885.AUEY01000013_gene3100	1.151e-35	144.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,42T3V@68525|delta/epsilon subdivisions,2WPYF@28221|Deltaproteobacteria,2MKDN@213118|Desulfobacterales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SX3_k127_6235172_0	1123401.JHYQ01000012_gene2888	3.039e-77	273.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,1T212@1236|Gammaproteobacteria,45ZU6@72273|Thiotrichales	72273|Thiotrichales	H	Thiamine biosynthesis protein (ThiI)	-	-	-	-	-	-	-	-	-	-	-	-	ThiI
SX3_k127_6235172_1	1121377.KB906409_gene867	3.422e-62	224.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	MA20_01210	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SX3_k127_6238421_1	1211114.ALIP01000083_gene1536	2.443e-18	87.0	COG1131@1|root,COG1131@2|Bacteria,1MY19@1224|Proteobacteria,1RQ0Z@1236|Gammaproteobacteria,1X4K5@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC transporter	yfiL	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SX3_k127_6238421_0	1124780.ANNU01000002_gene1509	1.382e-192	641.0	COG0308@1|root,COG0308@2|Bacteria,4NF3R@976|Bacteroidetes,47N7W@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4,ABC2_membrane_5,Peptidase_M1
SX3_k127_6243440_1	1121423.JONT01000006_gene2455	1.093e-31	128.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia	186801|Clostridia	P	Belongs to the Fur family	perR	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2000374,GO:2001141	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SX3_k127_6243440_0	1121422.AUMW01000026_gene412	5.636e-51	187.0	COG1592@1|root,COG1853@1|root,COG1592@2|Bacteria,COG1853@2|Bacteria,1V3CX@1239|Firmicutes,24IC2@186801|Clostridia,261SK@186807|Peptococcaceae	186801|Clostridia	C	PFAM Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SX3_k127_626243_2	204669.Acid345_1621	8.536e-87	295.0	COG0845@1|root,COG0845@2|Bacteria,3Y50Z@57723|Acidobacteria,2JMYN@204432|Acidobacteriia	204432|Acidobacteriia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SX3_k127_626243_1	204669.Acid345_1620	1.177e-105	347.0	COG1136@1|root,COG1136@2|Bacteria,3Y4A6@57723|Acidobacteria,2JMVQ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SX3_k127_626243_0	204669.Acid345_1619	1.005e-108	365.0	COG0577@1|root,COG0577@2|Bacteria,3Y4MY@57723|Acidobacteria,2JMXU@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SX3_k127_626243_3	204669.Acid345_1618	2.995e-27	127.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SX3_k127_627303_0	1189612.A33Q_4178	4.271e-27	122.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SX3_k127_6278203_1	926550.CLDAP_14500	1.985e-56	216.0	COG0013@1|root,COG0013@2|Bacteria,2G6Z3@200795|Chloroflexi	200795|Chloroflexi	J	Threonyl alanyl tRNA synthetase SAD	-	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SX3_k127_6278203_0	335543.Sfum_0723	5.155e-65	242.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,2MQBE@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SX3_k127_6278661_0	880072.Desac_2080	1.046e-30	131.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,42N6V@68525|delta/epsilon subdivisions,2WIQC@28221|Deltaproteobacteria,2MR1S@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH,NTP_transferase
SX3_k127_6278661_1	251221.35211032	2.157e-27	124.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	cugP	GO:0000166,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0003983,GO:0005488,GO:0006011,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009225,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0051748,GO:0055086,GO:0070569,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SX3_k127_6283137_1	572547.Amico_1356	5.732e-18	96.0	COG0392@1|root,COG0392@2|Bacteria,3TAD0@508458|Synergistetes	508458|Synergistetes	S	PFAM Uncharacterised protein family (UPF0104)	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SX3_k127_6283137_0	697303.Thewi_2042	5.7e-86	291.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,42EK9@68295|Thermoanaerobacterales	186801|Clostridia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SX3_k127_628366_0	593750.Metfor_1577	2.527e-10	73.0	arCOG13746@1|root,arCOG13746@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_6283965_4	45351.EDO25328	2.503e-19	98.0	28JEB@1|root,2QRTB@2759|Eukaryota	2759|Eukaryota	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP_2
SX3_k127_6283965_5	880073.Calab_3296	9.259e-05	53.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
SX3_k127_6283965_3	521674.Plim_1455	2.18e-49	182.0	COG0461@1|root,COG0461@2|Bacteria,2IZA7@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SX3_k127_6283965_1	991.IW20_17040	7.762e-103	350.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1HXFB@117743|Flavobacteriia,2NTK7@237|Flavobacterium	976|Bacteroidetes	E	Asparaginase	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
SX3_k127_6283965_2	522772.Dacet_1999	8.869e-80	273.0	COG0479@1|root,COG0479@2|Bacteria,2GF2E@200930|Deferribacteres	200930|Deferribacteres	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
SX3_k127_6283965_0	309801.trd_0331	5.958e-178	569.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,27XUB@189775|Thermomicrobia	189775|Thermomicrobia	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SX3_k127_6286005_0	1216007.AOPM01000075_gene1235	1.85e-15	90.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RQCR@1236|Gammaproteobacteria,2Q1TR@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Y_Y_Y
SX3_k127_6289569_0	479434.Sthe_3251	6.43e-184	586.0	COG1690@1|root,COG1690@2|Bacteria,2G5NT@200795|Chloroflexi,27XP1@189775|Thermomicrobia	189775|Thermomicrobia	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SX3_k127_6289569_1	580340.Tlie_0614	3.975e-128	418.0	COG0535@1|root,COG0535@2|Bacteria,3TAMG@508458|Synergistetes	508458|Synergistetes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SX3_k127_6292532_1	945713.IALB_0203	1.694e-119	390.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	f42a	-	-	-	-	-	-	-	-	-	-	-	Band_7
SX3_k127_6292532_2	526227.Mesil_0344	5.915e-15	77.0	COG4877@1|root,COG4877@2|Bacteria,1WKMS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_5
SX3_k127_6292532_0	575540.Isop_3575	8.909e-170	546.0	COG0531@1|root,COG0531@2|Bacteria,2IXT5@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SX3_k127_6294319_1	96561.Dole_0237	2.303e-13	75.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,42MYQ@68525|delta/epsilon subdivisions,2WJM2@28221|Deltaproteobacteria,2MIQM@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SX3_k127_6294319_0	404589.Anae109_2307	6.845e-32	141.0	COG2819@1|root,COG2819@2|Bacteria,1R54Q@1224|Proteobacteria	1224|Proteobacteria	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
SX3_k127_6306258_3	573061.Clocel_3410	1.353e-40	154.0	COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,36FQY@31979|Clostridiaceae	186801|Clostridia	C	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
SX3_k127_6306258_1	552811.Dehly_0623	1.962e-50	191.0	COG3383@1|root,COG3383@2|Bacteria,2GAS8@200795|Chloroflexi,34D7W@301297|Dehalococcoidia	301297|Dehalococcoidia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4
SX3_k127_6306258_2	429009.Adeg_0158	2.439e-43	164.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24I29@186801|Clostridia,42ICW@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SX3_k127_6306258_0	1499967.BAYZ01000171_gene5566	3.196e-202	638.0	COG1894@1|root,COG1894@2|Bacteria,2NNM1@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	bamH	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_2080	2Fe-2S_thioredx,Complex1_51K,Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2,SLBB
SX3_k127_6311984_0	234267.Acid_4819	2.071e-34	151.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,3Y8M9@57723|Acidobacteria	57723|Acidobacteria	KMT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Peptidase_M56,TonB_C
SX3_k127_6313915_0	485915.Dret_1750	3.728e-110	367.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N,XFP,XFP_N
SX3_k127_6325823_0	671143.DAMO_2768	7.32e-34	138.0	COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SX3_k127_6325823_1	468059.AUHA01000003_gene1902	5.822e-20	94.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
SX3_k127_6330502_0	1408473.JHXO01000011_gene3168	1.272e-49	188.0	COG1680@1|root,COG1729@1|root,COG1680@2|Bacteria,COG1729@2|Bacteria,4NI1Z@976|Bacteroidetes,2FUDK@200643|Bacteroidia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SX3_k127_6330502_4	574087.Acear_0772	0.0006981	51.0	COG0810@1|root,COG0810@2|Bacteria,1VN7X@1239|Firmicutes,25413@186801|Clostridia,3WC1R@53433|Halanaerobiales	186801|Clostridia	M	TIGRFAM TonB family protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
SX3_k127_6330502_2	1089551.KE386572_gene1872	1.508e-09	65.0	COG0848@1|root,COG0848@2|Bacteria,1RDJZ@1224|Proteobacteria,2U77T@28211|Alphaproteobacteria,4BSI9@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	U	Biopolymer transport protein ExbD/TolR	exbD	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SX3_k127_6330502_3	592316.Pat9b_3357	1.427e-06	59.0	COG0848@1|root,COG0848@2|Bacteria,1RDJZ@1224|Proteobacteria,1S3TA@1236|Gammaproteobacteria,3W0MI@53335|Pantoea	1236|Gammaproteobacteria	U	involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	iPC815.YPO0683	ExbD
SX3_k127_6330502_1	190304.FN1312	4.408e-15	80.0	COG0811@1|root,COG0811@2|Bacteria,379HA@32066|Fusobacteria	32066|Fusobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
SX3_k127_6332072_0	338966.Ppro_3623	1.982e-24	115.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria,43T3A@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
SX3_k127_6339924_0	330214.NIDE3435	3.516e-61	220.0	COG1131@1|root,COG1131@2|Bacteria,3J122@40117|Nitrospirae	40117|Nitrospirae	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SX3_k127_6339924_1	1265505.ATUG01000003_gene184	1.762e-25	116.0	COG1277@1|root,COG1277@2|Bacteria,1NCXV@1224|Proteobacteria,42VK2@68525|delta/epsilon subdivisions,2WRNT@28221|Deltaproteobacteria,2MPXF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SX3_k127_6342599_3	243164.DET0730	1.602e-23	117.0	COG3383@1|root,COG3383@2|Bacteria,2GAS8@200795|Chloroflexi,34D7W@301297|Dehalococcoidia	301297|Dehalococcoidia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4
SX3_k127_6342599_0	243164.DET0729	8.579e-272	848.0	COG1894@1|root,COG1894@2|Bacteria,2G5K9@200795|Chloroflexi,34D48@301297|Dehalococcoidia	301297|Dehalococcoidia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
SX3_k127_6342599_2	404380.Gbem_1449	4.797e-46	171.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,42RCD@68525|delta/epsilon subdivisions,2WMUP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	bamG	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SX3_k127_6342599_1	56780.SYN_00154	1.825e-129	420.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,2MQUN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ferredoxin oxidoreductase beta subunit	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SX3_k127_6347352_1	876269.ARWA01000001_gene3721	6.363e-14	78.0	COG2172@1|root,COG2172@2|Bacteria,1N9RD@1224|Proteobacteria,2UCGB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
SX3_k127_6347352_2	1410609.JHVB01000001_gene1963	8.37e-11	68.0	COG1366@1|root,COG1366@2|Bacteria,2JAZB@203691|Spirochaetes	203691|Spirochaetes	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_6347352_0	1122927.KB895436_gene4314	1.536e-29	124.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,26TDT@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SX3_k127_6356850_1	443906.CMM_2809	0.0003319	53.0	COG0477@1|root,COG2814@2|Bacteria,2GKMQ@201174|Actinobacteria,4FQCE@85023|Microbacteriaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SX3_k127_6356850_0	870187.Thini_3374	3.571e-05	57.0	COG1729@1|root,COG4249@1|root,COG1729@2|Bacteria,COG4249@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,460ZY@72273|Thiotrichales	72273|Thiotrichales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
SX3_k127_6380736_0	1379698.RBG1_1C00001G0226	2.171e-44	181.0	COG1729@1|root,COG1729@2|Bacteria,2NPUR@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
SX3_k127_6380736_1	1122132.AQYH01000002_gene1223	3.056e-18	86.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2TSTM@28211|Alphaproteobacteria,4B96X@82115|Rhizobiaceae	28211|Alphaproteobacteria	F	dihydroorotase	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SX3_k127_638153_0	398767.Glov_1091	1.14e-48	192.0	COG5316@1|root,COG5316@2|Bacteria,1N0IJ@1224|Proteobacteria	1224|Proteobacteria	S	N-terminal domain of unknown function (DUF4140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
SX3_k127_6383314_2	1118054.CAGW01000001_gene173	7.138e-51	196.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,26S55@186822|Paenibacillaceae	91061|Bacilli	S	DHH family	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SX3_k127_6383314_3	265072.Mfla_0068	1.009e-20	98.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2VR43@28216|Betaproteobacteria,2KMXN@206350|Nitrosomonadales	206350|Nitrosomonadales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SX3_k127_6383314_4	880073.Calab_3553	4.532e-13	74.0	COG1550@1|root,COG1550@2|Bacteria,2NPYX@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF503)	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SX3_k127_6383314_0	945713.IALB_0639	7.719e-210	674.0	COG0532@1|root,COG0532@2|Bacteria	2|Bacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
SX3_k127_6383314_1	1379698.RBG1_1C00001G1152	7.87e-115	389.0	COG0195@1|root,COG0195@2|Bacteria,2NNV1@2323|unclassified Bacteria	2|Bacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
SX3_k127_638477_1	379066.GAU_1141	7.062e-05	45.0	COG0577@1|root,COG0577@2|Bacteria,1ZUMY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SX3_k127_638477_0	661478.OP10G_0730	5.313e-38	158.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asp_protease_2,PDZ,PDZ_2,Peptidase_M28,Peptidase_S55
SX3_k127_6385297_0	234267.Acid_3413	4.597e-24	105.0	COG2204@1|root,COG2204@2|Bacteria,3Y2J1@57723|Acidobacteria	57723|Acidobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SX3_k127_6385297_1	313624.NSP_21450	3.349e-14	84.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1HK1F@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
SX3_k127_6386394_0	382464.ABSI01000011_gene3193	3.154e-42	173.0	COG0793@1|root,COG0793@2|Bacteria,46WA2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Tricorn protease C1 domain	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41,Tricorn_C1
SX3_k127_6386394_1	383372.Rcas_0195	1.509e-11	77.0	COG0457@1|root,COG0457@2|Bacteria,2GB3M@200795|Chloroflexi,377UW@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
SX3_k127_6386394_2	945713.IALB_2399	9.202e-05	45.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K13687	-	-	-	-	ko00000,ko01000,ko01003	-	GT89	-	DUF2723,PMT_2
SX3_k127_639231_0	378806.STAUR_5560	3.905e-29	121.0	COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria,2YYUP@29|Myxococcales	28221|Deltaproteobacteria	M	Phosphomethylpyrimidine kinase	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
SX3_k127_639231_1	34007.IT40_19995	7.761e-08	64.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2TQJM@28211|Alphaproteobacteria,2PUG1@265|Paracoccus	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	lpcC	-	-	ko:K12989	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glycos_transf_1
SX3_k127_6392429_1	1541065.JRFE01000006_gene4692	1.075e-17	92.0	2BDP7@1|root,327CQ@2|Bacteria,1GCJ7@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_6392429_0	459349.CLOAM0604	3.355e-19	101.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_6394134_1	546271.Selsp_1674	1.113e-38	151.0	COG1871@1|root,COG1871@2|Bacteria,1V70X@1239|Firmicutes,4H415@909932|Negativicutes	909932|Negativicutes	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
SX3_k127_6394134_0	342949.PNA2_1133	2.532e-80	287.0	COG2201@1|root,arCOG02382@2157|Archaea,2XUKR@28890|Euryarchaeota,2433H@183968|Thermococci	183968|Thermococci	N	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SX3_k127_6394134_2	243231.GSU3199	5.974e-23	115.0	COG0643@1|root,COG0643@2|Bacteria,1NW7P@1224|Proteobacteria,42PGY@68525|delta/epsilon subdivisions,2WM89@28221|Deltaproteobacteria,43T85@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase homodimeric	difE	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
SX3_k127_6414344_2	1379698.RBG1_1C00001G1789	4.166e-25	122.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
SX3_k127_6414344_3	760142.Hipma_0205	7.997e-17	82.0	COG2835@1|root,COG2835@2|Bacteria,1Q1BG@1224|Proteobacteria,42WTN@68525|delta/epsilon subdivisions,2WSI9@28221|Deltaproteobacteria,2M7FV@213113|Desulfurellales	28221|Deltaproteobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SX3_k127_6414344_1	880073.Calab_2091	5.422e-31	132.0	2CBA8@1|root,30BZT@2|Bacteria,2NR2H@2323|unclassified Bacteria	2|Bacteria	S	Exopolysaccharide biosynthesis protein YbjH	-	-	-	-	-	-	-	-	-	-	-	-	YjbH
SX3_k127_6414344_0	644282.Deba_2373	5.749e-284	902.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SX3_k127_6418850_1	391596.PBAL39_00285	4.074e-33	146.0	COG3049@1|root,COG3049@2|Bacteria,4NKSG@976|Bacteroidetes,1IU08@117747|Sphingobacteriia	976|Bacteroidetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_6418850_0	452637.Oter_3660	3.287e-43	177.0	COG0793@1|root,COG0793@2|Bacteria,46Z7X@74201|Verrucomicrobia	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41
SX3_k127_6430680_0	1499967.BAYZ01000115_gene2927	2.393e-122	403.0	COG0216@1|root,COG0216@2|Bacteria,2NNKY@2323|unclassified Bacteria	2|Bacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SX3_k127_6430680_1	240016.ABIZ01000001_gene2170	6.051e-09	59.0	COG2890@1|root,COG2890@2|Bacteria,46SZE@74201|Verrucomicrobia,2IU5P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SX3_k127_6450999_0	1379698.RBG1_1C00001G0435	4.292e-89	327.0	COG1747@1|root,COG1747@2|Bacteria,2NP33@2323|unclassified Bacteria	2|Bacteria	M	methyltransferase	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N,SprA_N
SX3_k127_6450999_1	1379698.RBG1_1C00001G1858	4.415e-69	249.0	COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ family protein	lptF	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207	YjgP_YjgQ
SX3_k127_6467328_0	518766.Rmar_2049	1.923e-210	672.0	COG1506@1|root,COG2706@1|root,COG1506@2|Bacteria,COG2706@2|Bacteria,4PIC9@976|Bacteroidetes,1FKAR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_6467328_1	1123256.KB907926_gene786	2.97e-49	182.0	COG0454@1|root,COG0454@2|Bacteria,1QTZ4@1224|Proteobacteria,1T2J8@1236|Gammaproteobacteria,1XDF9@135614|Xanthomonadales	135614|Xanthomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SX3_k127_6467328_2	309800.C498_06925	1.489e-05	55.0	COG0454@1|root,arCOG00826@2157|Archaea,2XXRF@28890|Euryarchaeota,23W1G@183963|Halobacteria	183963|Halobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SX3_k127_6472586_1	247490.KSU1_C1645	8.855e-10	61.0	COG0058@1|root,COG0058@2|Bacteria,2IY0J@203682|Planctomycetes	203682|Planctomycetes	G	COG0058 Glucan phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphorylase,YHS
SX3_k127_6472586_0	1408310.JHUW01000007_gene357	1.784e-14	79.0	2C1YS@1|root,2ZD2Y@2|Bacteria	2|Bacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SX3_k127_647353_0	867903.ThesuDRAFT_00417	3.952e-44	166.0	COG1225@1|root,COG1225@2|Bacteria,1UV64@1239|Firmicutes,24HTS@186801|Clostridia	186801|Clostridia	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SX3_k127_647353_1	713586.KB900537_gene3266	9.279e-44	166.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1X10Z@135613|Chromatiales	135613|Chromatiales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	-	-	-	-	-	-	-	-	-	SSB
SX3_k127_6475526_0	768671.ThimaDRAFT_4749	3.092e-63	232.0	COG0438@1|root,COG0438@2|Bacteria,1RCC7@1224|Proteobacteria,1S51S@1236|Gammaproteobacteria,1X1N0@135613|Chromatiales	135613|Chromatiales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SX3_k127_6485395_0	768710.DesyoDRAFT_3693	5.921e-46	186.0	COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,24AIF@186801|Clostridia,261A8@186807|Peptococcaceae	186801|Clostridia	C	PFAM Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
SX3_k127_6496816_2	243231.GSU1816	2.258e-26	110.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria,43TK5@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SX3_k127_6496816_0	880073.Calab_3419	4.719e-122	406.0	COG1088@1|root,COG1088@2|Bacteria,2NNRC@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	4.2.1.46,4.2.1.76	ko:K01710,ko:K12450	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R00293,R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3464	GDP_Man_Dehyd
SX3_k127_6496816_1	880073.Calab_0614	5.932e-120	413.0	COG0381@1|root,COG0381@2|Bacteria,2NNVT@2323|unclassified Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SX3_k127_6497556_0	635013.TherJR_2774	8.479e-80	283.0	COG3437@1|root,COG3437@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,267DF@186807|Peptococcaceae	186801|Clostridia	KT	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HD,Hpt,Response_reg
SX3_k127_650255_0	443143.GM18_4432	2.056e-56	206.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,42RI1@68525|delta/epsilon subdivisions,2WNBG@28221|Deltaproteobacteria,43UTQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SX3_k127_650255_2	997296.PB1_13224	4.664e-22	112.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HANF@91061|Bacilli,1ZS27@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SX3_k127_650255_3	316274.Haur_1422	1.539e-13	84.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2G93H@200795|Chloroflexi,375J3@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS
SX3_k127_650255_1	398767.Glov_0709	8.95e-25	112.0	COG2208@1|root,COG3850@1|root,COG2208@2|Bacteria,COG3850@2|Bacteria,1MXJQ@1224|Proteobacteria,42U7B@68525|delta/epsilon subdivisions,2WQA7@28221|Deltaproteobacteria,43VZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
SX3_k127_6502936_0	391625.PPSIR1_41924	3.839e-11	76.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SX3_k127_6516048_0	945713.IALB_3112	3.23e-162	535.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SX3_k127_6516048_1	1120966.AUBU01000002_gene2234	9.036e-51	195.0	COG1680@1|root,COG1680@2|Bacteria,4NHA7@976|Bacteroidetes,47R7U@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SX3_k127_653656_0	309807.SRU_1584	4.166e-06	59.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,1FJ24@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
SX3_k127_6557179_3	638302.HMPREF0908_0291	0.0004488	47.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1TT4Q@1239|Firmicutes,4H4I0@909932|Negativicutes	909932|Negativicutes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_6557179_0	1499967.BAYZ01000176_gene5652	1.91e-95	327.0	COG0451@1|root,COG0451@2|Bacteria,2NNT0@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	ytcB	-	5.1.3.2,5.1.3.6	ko:K01784,ko:K08679	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01385,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SX3_k127_6557179_1	479434.Sthe_0859	2.09e-94	319.0	COG0463@1|root,COG0463@2|Bacteria,2G5X5@200795|Chloroflexi,27XQE@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SX3_k127_6557179_2	419665.Maeo_0395	1.139e-38	150.0	COG0438@1|root,arCOG01415@2157|Archaea,2XUVW@28890|Euryarchaeota,23R82@183939|Methanococci	183939|Methanococci	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SX3_k127_656275_0	1122164.JHWF01000001_gene2031	8.494e-172	562.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1JDPB@118969|Legionellales	118969|Legionellales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SX3_k127_6586606_1	1242864.D187_010028	2.825e-09	68.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1Q3GC@1224|Proteobacteria,4340P@68525|delta/epsilon subdivisions,2X4G1@28221|Deltaproteobacteria,2YYY6@29|Myxococcales	28221|Deltaproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
SX3_k127_6586606_0	1122604.JONR01000031_gene1264	1.115e-31	139.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X59D@135614|Xanthomonadales	135614|Xanthomonadales	T	Sigma-54 interaction domain	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SX3_k127_6588875_0	1379698.RBG1_1C00001G0607	2.352e-172	567.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
SX3_k127_6599182_0	1231190.NA8A_03340	7.147e-57	203.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2TRNJ@28211|Alphaproteobacteria,43IN6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SX3_k127_6599182_1	404380.Gbem_0317	8.273e-43	158.0	COG1917@1|root,COG1917@2|Bacteria,1MZD8@1224|Proteobacteria,42W0P@68525|delta/epsilon subdivisions,2WRDR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SX3_k127_6599182_2	485916.Dtox_2997	3.57e-23	107.0	COG0655@1|root,COG0655@2|Bacteria,1UZKQ@1239|Firmicutes,25CAS@186801|Clostridia,265CK@186807|Peptococcaceae	186801|Clostridia	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SX3_k127_6612544_1	1379698.RBG1_1C00001G0498	4.503e-26	111.0	COG0848@1|root,COG0848@2|Bacteria,2NPWJ@2323|unclassified Bacteria	2|Bacteria	U	Biopolymer transport protein ExbD/TolR	tolR	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SX3_k127_6612544_2	1379698.RBG1_1C00001G0499	1.806e-16	87.0	COG0810@1|root,COG0810@2|Bacteria,2NQ3G@2323|unclassified Bacteria	2|Bacteria	M	TonB C terminal	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	CarbopepD_reg_2,TonB_2,TonB_C
SX3_k127_6612544_0	1379698.RBG1_1C00001G0500	4.891e-70	265.0	COG0823@1|root,COG0823@2|Bacteria,2NNZC@2323|unclassified Bacteria	2|Bacteria	U	TolB amino-terminal domain	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SX3_k127_6657698_2	880073.Calab_2056	2.946e-05	51.0	COG2372@1|root,COG2372@2|Bacteria,2NQ3Q@2323|unclassified Bacteria	2|Bacteria	S	Bacterial Ig-like domain	-	-	-	ko:K07156	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	Big_5,DUF4082,SLH
SX3_k127_6657698_0	880073.Calab_0179	7.613e-102	340.0	COG0078@1|root,COG0078@2|Bacteria,2NNWN@2323|unclassified Bacteria	2|Bacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SX3_k127_6657698_1	1121930.AQXG01000001_gene1396	2.547e-54	198.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,1IP2Y@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SX3_k127_6679711_0	1122138.AQUZ01000011_gene4922	3.147e-41	163.0	COG1835@1|root,COG1835@2|Bacteria,2GKUS@201174|Actinobacteria,4DS4D@85009|Propionibacteriales	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SX3_k127_6682110_1	604354.TSIB_0629	1.468e-33	138.0	COG1180@1|root,arCOG00952@2157|Archaea,2XZW0@28890|Euryarchaeota,244ZY@183968|Thermococci	183968|Thermococci	C	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
SX3_k127_6682110_0	706587.Desti_2378	1.967e-70	246.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	formate C-acetyltransferase glycine radical	-	-	-	-	-	-	-	-	-	-	-	-	Gly_radical,PFL-like
SX3_k127_6684572_0	880073.Calab_0089	6.893e-43	180.0	COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria	2|Bacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	-
SX3_k127_6690503_0	1347392.CCEZ01000075_gene3032	4.333e-44	172.0	COG0384@1|root,COG0384@2|Bacteria,1TRAF@1239|Firmicutes,25D2F@186801|Clostridia,36DVZ@31979|Clostridiaceae	186801|Clostridia	S	Phenazine biosynthesis protein, PhzF family	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SX3_k127_6690503_1	247490.KSU1_C1572	0.0002859	50.0	COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,2IWSR@203682|Planctomycetes	203682|Planctomycetes	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,Response_reg
SX3_k127_672115_1	177437.HRM2_04900	1.535e-44	167.0	COG0446@1|root,COG1142@1|root,COG1251@1|root,COG2080@1|root,COG0446@2|Bacteria,COG1142@2|Bacteria,COG1251@2|Bacteria,COG2080@2|Bacteria,1MVEK@1224|Proteobacteria,42P3Z@68525|delta/epsilon subdivisions,2WKRN@28221|Deltaproteobacteria,2MJ14@213118|Desulfobacterales	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer2_BFD,GCV_T,GCV_T_C,Pyr_redox_2
SX3_k127_672115_0	335543.Sfum_1801	1.622e-53	202.0	COG0247@1|root,COG0247@2|Bacteria,1R8YC@1224|Proteobacteria,42NJW@68525|delta/epsilon subdivisions,2WIX1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SX3_k127_6734908_1	1122925.KB895380_gene4209	1.354e-27	118.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,26QN5@186822|Paenibacillaceae	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB1	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SX3_k127_6734908_0	370438.PTH_0469	2.489e-82	284.0	COG1163@1|root,COG1163@2|Bacteria,1TSAP@1239|Firmicutes,24EEW@186801|Clostridia,260UT@186807|Peptococcaceae	186801|Clostridia	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
SX3_k127_6735692_0	880073.Calab_0681	2.053e-25	118.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,2NP51@2323|unclassified Bacteria	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	pkn5	-	2.7.11.1,3.1.3.3	ko:K04757,ko:K07315	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	AAA_16,GAF,HAMP,HATPase_c_2,Pkinase,SpoIIE,dCache_1
SX3_k127_6735692_1	264951.V5HYE8	0.0002022	53.0	COG0484@1|root,KOG0550@2759|Eukaryota,38CD1@33154|Opisthokonta,3NV1Y@4751|Fungi,3QQ9D@4890|Ascomycota,20BDM@147545|Eurotiomycetes,3S3YZ@5042|Eurotiales	4751|Fungi	O	DnaJ and TPR domain protein	-	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0030544,GO:0031072,GO:0051084,GO:0051085,GO:0061077	-	ko:K09527	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
SX3_k127_6736330_2	378806.STAUR_5358	2.908e-10	70.0	COG1729@1|root,COG1729@2|Bacteria,1N780@1224|Proteobacteria,42V4V@68525|delta/epsilon subdivisions,2WR6U@28221|Deltaproteobacteria,2YW0N@29|Myxococcales	28221|Deltaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_6736330_0	562970.Btus_0868	6.047e-85	297.0	COG1216@1|root,COG1216@2|Bacteria,1UYRR@1239|Firmicutes,4HEJ1@91061|Bacilli	91061|Bacilli	S	glycosyl transferase family 2	galnac-T15	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glyco_transf_7C,Glycos_transf_2
SX3_k127_6736330_1	521098.Aaci_0026	6.596e-12	71.0	COG0438@1|root,COG0438@2|Bacteria,1V0G0@1239|Firmicutes,4HCG7@91061|Bacilli,27A3C@186823|Alicyclobacillaceae	91061|Bacilli	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SX3_k127_6738741_0	880073.Calab_2746	1.164e-07	65.0	COG0457@1|root,COG0457@2|Bacteria	880073.Calab_2746|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_687938_0	477228.YO5_04157	2.234e-133	437.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1Z0U4@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Peptidase U62, modulator of DNA gyrase	tldD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SX3_k127_693807_2	880073.Calab_0807	2.817e-28	119.0	COG0469@1|root,COG0469@2|Bacteria,2NNKX@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the pyruvate kinase family	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iAF987.Gmet_0122	PK,PK_C
SX3_k127_693807_0	1288826.MSNKSG1_06903	1.187e-44	176.0	COG0297@1|root,COG0297@2|Bacteria,1QXFW@1224|Proteobacteria,1T3AX@1236|Gammaproteobacteria,46D4C@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SX3_k127_693807_1	1449126.JQKL01000003_gene1722	1.433e-39	151.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia,2687B@186813|unclassified Clostridiales	186801|Clostridia	S	4Fe-4S dicluster domain	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
SX3_k127_698523_1	671143.DAMO_1411	1.975e-11	72.0	COG3166@1|root,COG3166@2|Bacteria	2|Bacteria	NU	PFAM Fimbrial assembly family protein	pilN	-	-	ko:K02662,ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
SX3_k127_698523_0	1125863.JAFN01000001_gene2287	4.621e-28	120.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SX3_k127_720636_2	96561.Dole_0810	2.311e-09	61.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42P7V@68525|delta/epsilon subdivisions,2WJQA@28221|Deltaproteobacteria,2MJ2Q@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
SX3_k127_720636_0	96561.Dole_0809	1.819e-94	319.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria,2MIZ9@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
SX3_k127_720636_1	96561.Dole_0808	1.843e-45	169.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42PIB@68525|delta/epsilon subdivisions,2WKFC@28221|Deltaproteobacteria,2MMZK@213118|Desulfobacterales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SX3_k127_725372_1	742821.HMPREF9464_02226	0.0003133	43.0	COG0644@1|root,COG0644@2|Bacteria,1MVU6@1224|Proteobacteria,2VH37@28216|Betaproteobacteria,4PRVX@995019|Sutterellaceae	28216|Betaproteobacteria	C	GDP dissociation inhibitor	fixC	-	-	ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,FAD_oxidored,GIDA,Pyr_redox_2
SX3_k127_725372_0	1047013.AQSP01000126_gene2731	2.6e-152	495.0	COG0446@1|root,COG1142@1|root,COG1251@1|root,COG2080@1|root,COG0446@2|Bacteria,COG1142@2|Bacteria,COG1251@2|Bacteria,COG2080@2|Bacteria,2NP2E@2323|unclassified Bacteria	2|Bacteria	C	FAD dependent oxidoreductase	-	-	1.12.5.1,1.2.5.3,1.3.99.16,1.7.1.15	ko:K00205,ko:K00362,ko:K02573,ko:K03518,ko:K05927,ko:K07302	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00530,M00567	R00787,R03015,R08060,R11168,R11743	RC00176,RC00197,RC00323,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2,Fer2_4,Fer2_BFD,Fer4,Fer4_20,Fer4_7,GXGXG,NiFe_hyd_SSU_C,Oxidored_q6,Pyr_redox_2
SX3_k127_72879_0	445975.COLSTE_00864	6.392e-80	278.0	COG0409@1|root,COG0409@2|Bacteria,2GMHA@201174|Actinobacteria,4CUKQ@84998|Coriobacteriia	84998|Coriobacteriia	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
SX3_k127_72879_2	1321778.HMPREF1982_03233	5.396e-17	90.0	COG0298@1|root,COG0298@2|Bacteria	2|Bacteria	O	carbon dioxide binding	hypC	-	-	ko:K04653,ko:K04654	-	-	-	-	ko00000	-	-	-	HupF_HypC
SX3_k127_72879_1	56780.SYN_00599	7.22e-63	220.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2WK7X@28221|Deltaproteobacteria,2MR07@213462|Syntrophobacterales	28221|Deltaproteobacteria	KO	CobW/HypB/UreG, nucleotide-binding domain	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
SX3_k127_733525_0	697281.Mahau_2253	7.146e-45	173.0	COG0407@1|root,COG0407@2|Bacteria,1V4YU@1239|Firmicutes,24FCZ@186801|Clostridia,42HY1@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SX3_k127_733525_1	1123354.AUDR01000016_gene1336	1.368e-31	131.0	COG0284@1|root,COG0284@2|Bacteria,1MWH5@1224|Proteobacteria,2VHAB@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SX3_k127_733740_2	1089545.KB913037_gene9190	6.589e-08	58.0	COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria,4DXS1@85010|Pseudonocardiales	201174|Actinobacteria	Q	phytoene	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SX3_k127_733740_0	756067.MicvaDRAFT_0405	4.628e-11	72.0	COG2076@1|root,COG2076@2|Bacteria,1G6SF@1117|Cyanobacteria,1HC0R@1150|Oscillatoriales	1117|Cyanobacteria	P	PFAM Uncharacterised protein family UPF0546	-	-	-	-	-	-	-	-	-	-	-	-	EamA,TMEM234
SX3_k127_733740_1	1047013.AQSP01000113_gene742	2.005e-10	71.0	28V7D@1|root,2ZHAI@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
SX3_k127_740778_1	2423.NA23_0202310	1.275e-20	92.0	COG2201@1|root,COG2201@2|Bacteria,2GCZV@200918|Thermotogae	200918|Thermotogae	T	PFAM response regulator receiver	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SX3_k127_740778_0	379066.GAU_1408	8.137e-35	151.0	COG0457@1|root,COG0457@2|Bacteria,1ZSS6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
SX3_k127_757732_0	861299.J421_3007	4.912e-23	100.0	2EQ8R@1|root,33HV0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_757732_1	517417.Cpar_1801	1.188e-14	81.0	COG1266@1|root,COG1266@2|Bacteria,1FE3B@1090|Chlorobi	1090|Chlorobi	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SX3_k127_765131_1	671143.DAMO_0012	9.971e-156	511.0	COG1966@1|root,COG1966@2|Bacteria,2NNP2@2323|unclassified Bacteria	2|Bacteria	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
SX3_k127_765131_0	945713.IALB_2868	2.435e-265	824.0	COG2986@1|root,COG2986@2|Bacteria	2|Bacteria	E	ammonia-lyase activity	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SX3_k127_77198_0	335543.Sfum_0929	5.436e-115	391.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MQUW@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SX3_k127_780303_0	1408473.JHXO01000012_gene318	8.452e-102	341.0	COG1131@1|root,COG1131@2|Bacteria,4NMN9@976|Bacteroidetes	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SX3_k127_781273_0	1191523.MROS_2693	3.285e-110	360.0	COG0459@1|root,COG0459@2|Bacteria	2|Bacteria	O	protein refolding	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SX3_k127_781273_1	1379698.RBG1_1C00001G0288	1.31e-33	132.0	COG0234@1|root,COG0234@2|Bacteria,2NPW2@2323|unclassified Bacteria	2|Bacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SX3_k127_781273_2	794903.OPIT5_07195	4.063e-25	114.0	COG1521@1|root,COG1521@2|Bacteria,46T0X@74201|Verrucomicrobia,3K817@414999|Opitutae	414999|Opitutae	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SX3_k127_787775_2	1184267.A11Q_2181	1.11e-27	118.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2MU5K@213481|Bdellovibrionales,2WT56@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SX3_k127_787775_1	1043205.AFYF01000026_gene404	4.043e-47	191.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,4FEM5@85021|Intrasporangiaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SX3_k127_787775_0	1379698.RBG1_1C00001G0322	8.616e-55	207.0	COG2385@1|root,COG2385@2|Bacteria,2NPRR@2323|unclassified Bacteria	2|Bacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
SX3_k127_798734_1	448385.sce3387	2.116e-67	241.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_798734_0	760192.Halhy_1744	1.103e-82	287.0	COG0641@1|root,COG0641@2|Bacteria,4NG1N@976|Bacteroidetes,1IUNW@117747|Sphingobacteriia	976|Bacteroidetes	C	Anaerobic sulfatase maturase	atsB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SX3_k127_799630_0	1379698.RBG1_1C00001G1850	9.382e-43	163.0	COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria	2|Bacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SX3_k127_80016_0	882083.SacmaDRAFT_1933	8.766e-11	72.0	COG0247@1|root,COG0247@2|Bacteria,2GJ7M@201174|Actinobacteria,4DYWI@85010|Pseudonocardiales	201174|Actinobacteria	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SX3_k127_80016_1	326427.Cagg_2652	0.0005426	49.0	COG0457@1|root,COG1352@1|root,COG0457@2|Bacteria,COG1352@2|Bacteria,2G79T@200795|Chloroflexi,3765U@32061|Chloroflexia	32061|Chloroflexia	NT	PFAM MCP methyltransferase CheR-type	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,TPR_16
SX3_k127_800606_1	1379698.RBG1_1C00001G1817	2.226e-05	57.0	COG0308@1|root,COG0308@2|Bacteria,2NRIZ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Cofac_haem_bdg,NAAA-beta,Peptidase_M1,Phospholip_B
SX3_k127_800606_0	459349.CLOAM0604	2.258e-18	98.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_810670_2	1047013.AQSP01000134_gene1374	8.771e-34	147.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K16919	ko02010,map02010	M00254,M00584	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,ABC_transp_aux
SX3_k127_810670_0	1047013.AQSP01000134_gene1373	3.281e-85	296.0	COG1131@1|root,COG1131@2|Bacteria,2NR18@2323|unclassified Bacteria	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SX3_k127_810670_1	1122931.AUAE01000013_gene2071	9.987e-38	148.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,DUF4625,NPCBM_assoc,PEGA
SX3_k127_817601_0	945713.IALB_0016	1.335e-07	63.0	2EGEF@1|root,33A6F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_818656_0	309803.CTN_0554	4.274e-74	267.0	COG0820@1|root,COG0820@2|Bacteria,2GC4T@200918|Thermotogae	200918|Thermotogae	J	PFAM Radical SAM domain protein	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	-
SX3_k127_818656_1	1121468.AUBR01000032_gene1192	2.815e-27	123.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,42EKM@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SX3_k127_818656_2	278963.ATWD01000002_gene883	4.004e-25	108.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,3Y3GW@57723|Acidobacteria,2JHKK@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
SX3_k127_822416_0	1313301.AUGC01000006_gene21	1.295e-11	77.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
SX3_k127_826073_3	317655.Sala_1868	0.0003718	44.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2TR6C@28211|Alphaproteobacteria,2K0IW@204457|Sphingomonadales	204457|Sphingomonadales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SX3_k127_826073_2	479434.Sthe_1286	2.355e-40	153.0	COG0509@1|root,COG0509@2|Bacteria,2G6XE@200795|Chloroflexi,27YEK@189775|Thermomicrobia	189775|Thermomicrobia	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SX3_k127_826073_0	1121428.DESHY_50079___1	1.376e-97	331.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,248U7@186801|Clostridia,261AX@186807|Peptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SX3_k127_826073_1	351627.Csac_1984	1.724e-81	275.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,42EYE@68295|Thermoanaerobacterales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SX3_k127_826671_0	443143.GM18_1696	2.008e-111	390.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,43SYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
SX3_k127_831551_2	1150621.SMUL_2298	2.232e-40	160.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2YNW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SX3_k127_831551_0	1121468.AUBR01000017_gene2358	1.774e-142	465.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,42FB3@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SX3_k127_831551_1	1232410.KI421419_gene2512	4.189e-45	175.0	COG3875@1|root,COG3875@2|Bacteria,1R79Y@1224|Proteobacteria,42PGD@68525|delta/epsilon subdivisions,2WMB6@28221|Deltaproteobacteria,43T90@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SX3_k127_836334_0	234267.Acid_0851	5.554e-99	335.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41,Tricorn_C1
SX3_k127_840523_0	553177.CAPSP0001_1578	1.098e-10	74.0	COG3522@1|root,COG3522@2|Bacteria,4NGBP@976|Bacteroidetes,1HZZS@117743|Flavobacteriia,1ERRY@1016|Capnocytophaga	976|Bacteroidetes	S	type VI secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	T6SS_VasE
SX3_k127_840523_1	342113.DM82_5815	0.0001721	53.0	COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,2W22X@28216|Betaproteobacteria,1K4BQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Type VI secretion, TssG	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
SX3_k127_850298_2	443144.GM21_1446	4.245e-41	171.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,43TCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SX3_k127_850298_0	1379698.RBG1_1C00001G1326	4.045e-152	498.0	COG2006@1|root,COG2006@2|Bacteria,2NPTK@2323|unclassified Bacteria	2|Bacteria	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4
SX3_k127_850298_1	1499967.BAYZ01000193_gene3921	2.008e-65	236.0	COG0382@1|root,COG0382@2|Bacteria,2NNVJ@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
SX3_k127_850298_3	1131269.AQVV01000008_gene924	9.276e-35	148.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SX3_k127_852455_0	177437.HRM2_22720	1.271e-51	196.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria,2MIN8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
SX3_k127_854823_0	1121472.AQWN01000008_gene1913	2.738e-192	621.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,26166@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Pyr_redox_2
SX3_k127_854823_1	1121472.AQWN01000008_gene1912	3.981e-45	172.0	COG1908@1|root,COG1908@2|Bacteria,1V80C@1239|Firmicutes,24MB7@186801|Clostridia,264Z4@186807|Peptococcaceae	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD
SX3_k127_854823_2	935863.AWZR01000004_gene448	1.947e-18	88.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1X7P3@135614|Xanthomonadales	135614|Xanthomonadales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
SX3_k127_871844_0	880073.Calab_3525	4.199e-116	396.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SX3_k127_879588_0	398767.Glov_0464	2.199e-59	221.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM FAD linked oxidase domain protein	larD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3245	FAD-oxidase_C,FAD_binding_4
SX3_k127_879588_1	59374.Fisuc_0116	3.528e-12	67.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SX3_k127_888457_2	1122247.C731_2752	1.559e-15	86.0	COG3340@1|root,COG3340@2|Bacteria,2IC7Y@201174|Actinobacteria,234WT@1762|Mycobacteriaceae	201174|Actinobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SX3_k127_888457_1	1269813.ATUL01000002_gene912	9.95e-20	103.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria,1WWSV@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
SX3_k127_888457_0	880073.Calab_1595	1.469e-153	494.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SX3_k127_893117_1	1123276.KB893245_gene1164	8.848e-08	59.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,47M4V@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
SX3_k127_893117_0	1089553.Tph_c02680	1.377e-124	415.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,42EJW@68295|Thermoanaerobacterales	186801|Clostridia	GM	PFAM Polysaccharide biosynthesis protein	epsC	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_syn_2C,Polysacc_synt_2
SX3_k127_893340_0	224324.aq_298	4.414e-88	301.0	COG0172@1|root,COG0172@2|Bacteria,2G3RF@200783|Aquificae	200783|Aquificae	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SX3_k127_893340_2	1123288.SOV_3c08550	7.442e-28	125.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H1XA@909932|Negativicutes	909932|Negativicutes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SX3_k127_893340_1	264732.Moth_0218	5.053e-43	170.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,247M7@186801|Clostridia,42EVR@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Glycosyl transferase family 4	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SX3_k127_898348_0	1047013.AQSP01000126_gene2731	1.187e-194	631.0	COG0446@1|root,COG1142@1|root,COG1251@1|root,COG2080@1|root,COG0446@2|Bacteria,COG1142@2|Bacteria,COG1251@2|Bacteria,COG2080@2|Bacteria,2NP2E@2323|unclassified Bacteria	2|Bacteria	C	FAD dependent oxidoreductase	-	-	1.12.5.1,1.2.5.3,1.3.99.16,1.7.1.15	ko:K00205,ko:K00362,ko:K02573,ko:K03518,ko:K05927,ko:K07302	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00530,M00567	R00787,R03015,R08060,R11168,R11743	RC00176,RC00197,RC00323,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2,Fer2_4,Fer2_BFD,Fer4,Fer4_20,Fer4_7,GXGXG,NiFe_hyd_SSU_C,Oxidored_q6,Pyr_redox_2
SX3_k127_898348_1	335543.Sfum_1176	8.449e-46	177.0	COG0247@1|root,COG0247@2|Bacteria,1R8YC@1224|Proteobacteria,42NJW@68525|delta/epsilon subdivisions,2WIX1@28221|Deltaproteobacteria,2MR23@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SX3_k127_90302_3	387631.Asulf_02054	6.585e-05	52.0	COG2834@1|root,arCOG02470@2157|Archaea,2XWT9@28890|Euryarchaeota,246WN@183980|Archaeoglobi	183980|Archaeoglobi	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4367,LolA_like
SX3_k127_90302_0	237368.SCABRO_01368	3.925e-73	254.0	arCOG03165@1|root,30AIC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_90302_1	1123274.KB899427_gene3359	1.821e-27	128.0	COG1527@1|root,COG1527@2|Bacteria,2JADK@203691|Spirochaetes	203691|Spirochaetes	C	PFAM ATP synthase (C AC39) subunit	-	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
SX3_k127_90302_2	1123274.KB899427_gene3358	8.641e-13	79.0	COG1269@1|root,COG1269@2|Bacteria,2J6DX@203691|Spirochaetes	203691|Spirochaetes	U	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
SX3_k127_904114_0	269799.Gmet_3560	4.903e-85	295.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2WIWY@28221|Deltaproteobacteria,43TPQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
SX3_k127_920649_0	485913.Krac_3042	4.041e-94	321.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
SX3_k127_921510_0	1379698.RBG1_1C00001G0718	1.822e-75	265.0	COG0612@1|root,COG0612@2|Bacteria,2NPE5@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SX3_k127_921510_1	222534.KB893783_gene5335	1.992e-48	186.0	COG0702@1|root,COG0702@2|Bacteria,2IQ0Z@201174|Actinobacteria	201174|Actinobacteria	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Methyltransf_21,NAD_binding_10
SX3_k127_921510_2	1117319.PSPO_14628	4.661e-15	81.0	COG1506@1|root,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,1RPRK@1236|Gammaproteobacteria,2Q0HE@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	dpp4	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
SX3_k127_922440_2	1304885.AUEY01000044_gene226	1.682e-18	86.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKYI@28221|Deltaproteobacteria,2MJHB@213118|Desulfobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SX3_k127_922440_1	2423.NA23_0204940	4.299e-47	173.0	COG0432@1|root,COG0432@2|Bacteria,2GD2P@200918|Thermotogae	200918|Thermotogae	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SX3_k127_922440_0	945713.IALB_2155	3.496e-146	477.0	COG2195@1|root,COG2195@2|Bacteria	2|Bacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepD	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	iPC815.YPO3230,iSBO_1134.SBO_0243	M20_dimer,Peptidase_M20
SX3_k127_925483_0	926550.CLDAP_30940	2.06e-96	321.0	COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28,4.1.2.27	ko:K01593,ko:K01634	ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034	M00037,M00042,M00100	R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SX3_k127_925483_1	40384.G7XP58	3.037e-10	66.0	29PZC@1|root,2RX79@2759|Eukaryota,39VY5@33154|Opisthokonta,3NV72@4751|Fungi,3QQJ4@4890|Ascomycota,20QVU@147545|Eurotiomycetes,3SDSN@5042|Eurotiales	4751|Fungi	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SX3_k127_925890_0	338966.Ppro_1051	2.698e-185	586.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WKK3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SX3_k127_925890_3	1131462.DCF50_p850	2.384e-22	113.0	2E55P@1|root,32ZYJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_925890_1	1123367.C666_07450	9.058e-72	257.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,2KUP7@206389|Rhodocyclales	206389|Rhodocyclales	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SX3_k127_925890_2	868131.MSWAN_0651	5.574e-29	121.0	COG2006@1|root,arCOG02447@2157|Archaea,2XW1U@28890|Euryarchaeota	28890|Euryarchaeota	C	4Fe-4S ferredoxin iron-sulfur binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4,Fer4_7
SX3_k127_930778_2	1120950.KB892760_gene5716	3.213e-25	106.0	COG2185@1|root,COG2185@2|Bacteria,2IFJD@201174|Actinobacteria,4DQPH@85009|Propionibacteriales	201174|Actinobacteria	I	PFAM cobalamin B12-binding domain protein	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SX3_k127_930778_0	1379698.RBG1_1C00001G1459	6.952e-146	472.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SX3_k127_930778_1	1121472.AQWN01000003_gene1537	2.204e-104	346.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,260DQ@186807|Peptococcaceae	186801|Clostridia	I	PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SX3_k127_932742_3	365528.KB891103_gene3919	0.0001334	53.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,P_proprotein,Peptidase_S8
SX3_k127_932742_0	1125863.JAFN01000001_gene1921	8.213e-16	82.0	COG0296@1|root,COG0296@2|Bacteria,1NEFK@1224|Proteobacteria,42VRH@68525|delta/epsilon subdivisions,2WRD5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM glycoside hydrolase, family 13 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
SX3_k127_932742_1	391009.Tmel_0803	5.406e-15	80.0	COG1449@1|root,COG4945@1|root,COG1449@2|Bacteria,COG4945@2|Bacteria,2GC51@200918|Thermotogae	200918|Thermotogae	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Glucodextran_C,Glyco_hydro_57
SX3_k127_932742_2	941824.TCEL_01381	2.666e-09	70.0	COG0296@1|root,COG0366@1|root,COG0296@2|Bacteria,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,36EQD@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_N,Big_2,CBM_20,CBM_48,Cadherin-like,Malt_amylase_C,PUD,SLH
SX3_k127_948903_3	1120985.AUMI01000016_gene1879	1.007e-26	120.0	2FEBN@1|root,346BD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SX3_k127_948903_0	237368.SCABRO_01669	1.63e-99	338.0	COG0379@1|root,COG0379@2|Bacteria,2IXB1@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SX3_k127_948903_2	909663.KI867150_gene222	3.349e-51	200.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2WJBU@28221|Deltaproteobacteria,2MRQU@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NifU-like N terminal domain	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SX3_k127_948903_1	429009.Adeg_0423	2.204e-91	310.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42FGX@68295|Thermoanaerobacterales	186801|Clostridia	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SX3_k127_954255_0	97138.C820_02438	1.255e-06	55.0	COG0860@1|root,COG0860@2|Bacteria,1V4B9@1239|Firmicutes,24MC5@186801|Clostridia,36KDD@31979|Clostridiaceae	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
SX3_k127_965957_1	1499967.BAYZ01000002_gene5899	3.888e-113	373.0	COG0505@1|root,COG0505@2|Bacteria,2NNMS@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955,ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383	CPSase_sm_chain,GATase
SX3_k127_965957_4	290315.Clim_2247	3.337e-41	169.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_13,Methyltransf_14,Methyltransf_23,Methyltransf_25
SX3_k127_965957_3	1123368.AUIS01000033_gene1380	1.468e-56	214.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SX3_k127_965957_0	1519464.HY22_10360	2.305e-211	672.0	COG0154@1|root,COG0154@2|Bacteria,1FDMC@1090|Chlorobi	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SX3_k127_965957_2	519989.ECTPHS_10481	1.231e-64	231.0	COG1538@1|root,COG1538@2|Bacteria,1R705@1224|Proteobacteria,1S0X1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SX3_k127_976165_0	1336234.JAGN01000004_gene569	1.154e-42	166.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,27FCJ@186828|Carnobacteriaceae	91061|Bacilli	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SX3_k127_976165_1	319795.Dgeo_0700	1.046e-28	120.0	COG1963@1|root,COG1963@2|Bacteria,1WJV3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Acid phosphatase vanadium-dependent haloperoxidase related	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
SX3_k127_976165_2	161156.JQKW01000006_gene1076	4.693e-10	61.0	COG0747@1|root,COG0747@2|Bacteria,2GHG2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SX3_k127_97719_1	909663.KI867150_gene794	1.315e-22	104.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SX3_k127_97719_0	748449.Halha_2398	8.704e-52	194.0	COG1216@1|root,COG1216@2|Bacteria,1UIHC@1239|Firmicutes,25F9A@186801|Clostridia,3WADS@53433|Halanaerobiales	186801|Clostridia	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SX3_k127_985809_1	880073.Calab_3278	1.708e-58	216.0	COG3049@1|root,COG3049@2|Bacteria	2|Bacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
SX3_k127_985809_2	264731.PRU_0570	4.537e-28	115.0	COG3655@1|root,COG3655@2|Bacteria,4NUP7@976|Bacteroidetes,2FTVE@200643|Bacteroidia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
SX3_k127_985809_0	1499967.BAYZ01000119_gene3214	1.354e-70	250.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
SX3_k127_995483_0	1047013.AQSP01000131_gene1819	6.708e-59	220.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,DUF4625,NPCBM_assoc,PEGA
## 2198 queries scanned
## Total time (seconds): 492.90924620628357
## Rate: 4.46 q/s