## Thu Feb 19 13:13:24 2026 ## emapper-2.1.13 ## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/SYD1_bin.36.fa -m mmseqs --output SYD1_bin.36 --output_dir /data/result/bins/wyx/eggqs50+/SYD1_bin.36 --itype genome --cpu 8 --override ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs SYD1_k127_101046_2 1201290.M902_0943 3.744e-05 48.0 COG3170@1|root,COG3170@2|Bacteria,1QX7F@1224|Proteobacteria,42NQR@68525|delta/epsilon subdivisions,2WRZ7@28221|Deltaproteobacteria 28221|Deltaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - SYD1_k127_101046_0 1379698.RBG1_1C00001G0108 1.294e-69 247.0 COG0803@1|root,COG0803@2|Bacteria,2NPH3@2323|unclassified Bacteria 2|Bacteria P Belongs to the bacterial solute-binding protein 9 family znuA - - ko:K02077,ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA SYD1_k127_101046_1 1379698.RBG1_1C00001G0109 1.835e-54 214.0 COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria 2|Bacteria U ABC 3 transport family znuB - - ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC-3 SYD1_k127_113691_4 1033802.SSPSH_001036 2.43e-112 381.0 COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K07798,ko:K15727 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1,8.A.1.2.1 - - DUF3347,HlyD_D23,HlyD_D4,YtkA SYD1_k127_113691_0 483219.LILAB_03770 0.0 1355.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2YUB0@29|Myxococcales 28221|Deltaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - iAF987.Gmet_1547 ACR_tran SYD1_k127_113691_12 290397.Adeh_0300 6.104e-12 74.0 COG4633@1|root,COG4633@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Cupredoxin_1,DsbD_2,HMA SYD1_k127_113691_14 880073.Calab_2084 0.0001488 53.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - - - - - - - - - - C_GCAxxG_C_C,FlgD_ig,Peptidase_S74 SYD1_k127_113691_13 1396141.BATP01000047_gene3875 9.283e-07 61.0 COG1404@1|root,COG1404@2|Bacteria,46VVV@74201|Verrucomicrobia 74201|Verrucomicrobia O Belongs to the peptidase S8 family - - - - - - - - - - - - - SYD1_k127_113691_1 56110.Oscil6304_5436 3.114e-163 532.0 COG1282@1|root,COG1282@2|Bacteria,1G2AX@1117|Cyanobacteria,1H8G7@1150|Oscillatoriales 1117|Cyanobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB SYD1_k127_113691_11 497964.CfE428DRAFT_1190 3.938e-27 125.0 COG3288@1|root,COG3288@2|Bacteria,46T7S@74201|Verrucomicrobia 74201|Verrucomicrobia C 4TM region of pyridine nucleotide transhydrogenase, mitoch - - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM SYD1_k127_113691_2 32057.KB217478_gene7103 3.98e-127 418.0 COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,1HJ2V@1161|Nostocales 1117|Cyanobacteria C PFAM Alanine dehydrogenase PNT, C-terminal domain pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N SYD1_k127_113691_10 204669.Acid345_2164 1.068e-29 128.0 COG2318@1|root,COG2318@2|Bacteria,3Y501@57723|Acidobacteria,2JJGU@204432|Acidobacteriia 204432|Acidobacteriia S DinB superfamily - - - - - - - - - - - - DinB_2 SYD1_k127_113691_7 292459.STH2933 2.086e-46 188.0 COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,24JCU@186801|Clostridia 186801|Clostridia G peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 SYD1_k127_113691_6 765420.OSCT_0613 1.863e-54 204.0 COG0111@1|root,COG0111@2|Bacteria,2G6KY@200795|Chloroflexi,376P6@32061|Chloroflexia 32061|Chloroflexia C PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C SYD1_k127_113691_3 251221.35211773 2.698e-126 425.0 COG4805@1|root,COG4805@2|Bacteria 2|Bacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 SYD1_k127_113691_9 1123373.ATXI01000005_gene868 7.809e-32 136.0 COG0730@1|root,COG0730@2|Bacteria,2GHJ4@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE SYD1_k127_113691_8 215803.DB30_3946 6.227e-40 165.0 COG0642@1|root,COG2205@2|Bacteria,1QX6V@1224|Proteobacteria,43BZK@68525|delta/epsilon subdivisions,2X7AC@28221|Deltaproteobacteria,2YYIJ@29|Myxococcales 28221|Deltaproteobacteria T GAF domain - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_4 SYD1_k127_113691_5 1125863.JAFN01000001_gene1446 3.953e-61 219.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria 28221|Deltaproteobacteria T two component, sigma54 specific, transcriptional regulator, Fis family - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_1189337_12 557598.LHK_00141 5.152e-20 103.0 COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2VJAC@28216|Betaproteobacteria 28216|Betaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_D23 SYD1_k127_1189337_0 1303518.CCALI_01174 5.253e-313 1009.0 COG0841@1|root,COG0841@2|Bacteria 2|Bacteria V transmembrane transporter activity - - - - - - - - - - - - ACR_tran SYD1_k127_1189337_13 83406.HDN1F_09590 5.956e-20 97.0 COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,1J7D9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 SYD1_k127_1189337_10 479434.Sthe_1008 2.825e-44 183.0 COG0454@1|root,COG0456@2|Bacteria,2G6N6@200795|Chloroflexi 200795|Chloroflexi K PFAM GCN5-related N-acetyltransferase - - - - - - - - - - - - Acetyltransf_1 SYD1_k127_1189337_4 479434.Sthe_2315 2.024e-80 288.0 COG2855@1|root,COG2855@2|Bacteria,2G98G@200795|Chloroflexi 200795|Chloroflexi S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 SYD1_k127_1189337_5 644966.Tmar_0252 1.841e-76 278.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,25CRT@186801|Clostridia 186801|Clostridia P Rhodanese Homology Domain - - - - - - - - - - - - Lactamase_B,Rhodanese SYD1_k127_1189337_7 861299.J421_2928 1.82e-61 231.0 COG2385@1|root,COG2385@2|Bacteria,1ZT25@142182|Gemmatimonadetes 142182|Gemmatimonadetes D Stage II sporulation protein - - - ko:K06381 - - - - ko00000 - - - SpoIID SYD1_k127_1189337_6 1267533.KB906738_gene2106 1.566e-73 273.0 COG2377@1|root,COG2377@2|Bacteria,3Y3CU@57723|Acidobacteria,2JI1E@204432|Acidobacteriia 204432|Acidobacteriia O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK SYD1_k127_1189337_9 1449357.JQLK01000001_gene1817 5.826e-51 192.0 COG0395@1|root,COG0395@2|Bacteria,1WJJS@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G PFAM Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 SYD1_k127_1189337_8 1379698.RBG1_1C00001G0883 4.043e-59 230.0 COG1175@1|root,COG1175@2|Bacteria,2NPDA@2323|unclassified Bacteria 2|Bacteria G binding-protein-dependent transport systems inner membrane component - - - ko:K02025,ko:K15771 ko02010,map02010 M00207,M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 SYD1_k127_1189337_3 1379698.RBG1_1C00001G0884 2.874e-85 309.0 COG2182@1|root,COG2182@2|Bacteria 2|Bacteria G maltose binding - - - ko:K02027,ko:K17329 ko02010,map02010 M00207,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.33 - - SBP_bac_1,SBP_bac_8 SYD1_k127_1189337_2 518766.Rmar_2753 5.406e-88 314.0 COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1FIKZ@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 SYD1_k127_1189337_11 459349.CLOAM0429 2.951e-30 141.0 COG1572@1|root,COG1572@2|Bacteria,2NQER@2323|unclassified Bacteria 2|Bacteria S Peptidase family C25 - - - - - - - - - - - - FlgD_ig,Peptidase_C25,Propeptide_C25 SYD1_k127_1189337_1 1123242.JH636434_gene4155 1.04e-143 480.0 COG3379@1|root,COG3379@2|Bacteria,2IXA8@203682|Planctomycetes 203682|Planctomycetes S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest SYD1_k127_1189337_14 1324957.K933_10909 1.184e-16 92.0 COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,23SVZ@183963|Halobacteria 183963|Halobacteria I Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids ubiA2 - 2.5.1.42 ko:K17105 ko00564,map00564 - R04520 RC01171 ko00000,ko00001,ko01000 - - - UbiA SYD1_k127_1236413_52 1125863.JAFN01000001_gene620 8.154e-112 380.0 COG0367@1|root,COG0367@2|Bacteria,1PRFK@1224|Proteobacteria 1224|Proteobacteria E asparagine synthase asnB2 - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 SYD1_k127_1236413_121 443144.GM21_2464 9.855e-42 176.0 COG5653@1|root,COG5653@2|Bacteria,1NCB6@1224|Proteobacteria 1224|Proteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 SYD1_k127_1236413_116 1095769.CAHF01000010_gene1319 4.774e-44 181.0 COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,2VIWN@28216|Betaproteobacteria,474GQ@75682|Oxalobacteraceae 28216|Betaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 SYD1_k127_1236413_195 497321.C664_09600 0.0001107 52.0 COG0457@1|root,COG0457@2|Bacteria,1RIHH@1224|Proteobacteria,2VTBB@28216|Betaproteobacteria,2KWTV@206389|Rhodocyclales 206389|Rhodocyclales S TPR repeat - - - - - - - - - - - - TPR_11 SYD1_k127_1236413_182 596151.DesfrDRAFT_0414 5.141e-10 73.0 COG5305@1|root,COG5305@2|Bacteria,1R9UF@1224|Proteobacteria,43EPC@68525|delta/epsilon subdivisions,2X196@28221|Deltaproteobacteria,2MEI2@213115|Desulfovibrionales 28221|Deltaproteobacteria S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SYD1_k127_1236413_84 1121413.JMKT01000015_gene262 8.172e-76 273.0 COG2244@1|root,COG2244@2|Bacteria,1QZC3@1224|Proteobacteria,42U79@68525|delta/epsilon subdivisions,2WQ6Z@28221|Deltaproteobacteria,2MFJW@213115|Desulfovibrionales 28221|Deltaproteobacteria S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt SYD1_k127_1236413_61 1348657.M622_13850 7.576e-97 331.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VIBU@28216|Betaproteobacteria,2KUXN@206389|Rhodocyclales 206389|Rhodocyclales M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 SYD1_k127_1236413_77 1125863.JAFN01000001_gene630 8.856e-84 304.0 COG0438@1|root,COG0438@2|Bacteria,1R564@1224|Proteobacteria,42SAM@68525|delta/epsilon subdivisions,2WPCJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SYD1_k127_1236413_54 886293.Sinac_5461 1.223e-104 361.0 COG0438@1|root,COG0438@2|Bacteria,2J10U@203682|Planctomycetes 203682|Planctomycetes M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SYD1_k127_1236413_73 472759.Nhal_2167 6.081e-87 321.0 COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,1RPTR@1236|Gammaproteobacteria,1X25Y@135613|Chromatiales 135613|Chromatiales M Wzy family polymerase, exosortase system type 1 associated - - - - - - - - - - - - Wzy_C SYD1_k127_1236413_30 62928.azo3270 1.34e-140 457.0 COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria,2KUCI@206389|Rhodocyclales 206389|Rhodocyclales M Glycosyl transferases group 1 - - - ko:K00786 - - - - ko00000,ko01000 - - - Glyco_trans_1_4,Glyco_transf_4 SYD1_k127_1236413_31 1454004.AW11_02199 1.022e-139 457.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VMX7@28216|Betaproteobacteria 28216|Betaproteobacteria C Belongs to the UDP-glucose GDP-mannose dehydrogenase family algD - 1.1.1.132 ko:K00066 ko00051,ko00520,ko02020,map00051,map00520,map02020 - R00880 RC00291 ko00000,ko00001,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N SYD1_k127_1236413_149 62928.azo3263 1.151e-25 124.0 COG5492@1|root,COG5492@2|Bacteria 2|Bacteria N domain, Protein - - - - - - - - - - - - Big_2,Collagen_bind_2,DUF5060,NAGPA,SLH SYD1_k127_1236413_57 493475.GARC_1588 2.565e-100 348.0 COG5492@1|root,COG5492@2|Bacteria,1N06B@1224|Proteobacteria,1SGI3@1236|Gammaproteobacteria 1236|Gammaproteobacteria N domain, Protein - - - - - - - - - - - - - SYD1_k127_1236413_177 1033743.CAES01000085_gene2958 3.208e-12 78.0 COG1404@1|root,COG2730@1|root,COG1404@2|Bacteria,COG2730@2|Bacteria 2|Bacteria G polysaccharide catabolic process celA7 - 3.2.1.4,3.2.1.78 ko:K01179,ko:K01218 ko00051,ko00500,ko01100,ko02024,map00051,map00500,map01100,map02024 - R01332,R06200,R11307,R11308 RC00467 ko00000,ko00001,ko01000 - GH26,GH5,GH9 - CBM_3,CBM_35,F5_F8_type_C,Glyco_hydro_26,Glyco_hydro_44,Peptidase_S8,SLH,fn3 SYD1_k127_1236413_56 1163617.SCD_n02958 2.343e-100 349.0 COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2VMAH@28216|Betaproteobacteria 28216|Betaproteobacteria C Protein of unknown function (DUF3485) epsH - - - - - - - - - - - DUF3485,Exosortase_EpsH SYD1_k127_1236413_142 1089550.ATTH01000001_gene1005 4.951e-29 129.0 COG1404@1|root,COG3591@1|root,COG4932@1|root,COG1404@2|Bacteria,COG3591@2|Bacteria,COG4932@2|Bacteria,4NG2K@976|Bacteroidetes,1FJTD@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes EO Trypsin-like serine protease - - 3.4.21.50 ko:K01337 - - - - ko00000,ko01000,ko01002 - - - P_proprotein,Trypsin_2 SYD1_k127_1236413_184 246197.MXAN_5837 1.188e-09 70.0 COG4932@1|root,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,438GF@68525|delta/epsilon subdivisions,2X3RA@28221|Deltaproteobacteria,2YWWZ@29|Myxococcales 28221|Deltaproteobacteria M Bacterial Ig-like domain (group 1) - - - - - - - - - - - - Big_1,LTD SYD1_k127_1236413_194 518766.Rmar_2442 8.035e-06 57.0 COG0737@1|root,COG0737@2|Bacteria,4PNDC@976|Bacteroidetes,1FJX0@1100069|Bacteroidetes Order II. Incertae sedis 2|Bacteria F pectinesterase activity - - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - LRR_5,SBP_bac_8,TAT_signal SYD1_k127_1236413_99 243231.GSU1980 1.296e-62 227.0 COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,42P7W@68525|delta/epsilon subdivisions,2WMHU@28221|Deltaproteobacteria,43SFF@69541|Desulfuromonadales 28221|Deltaproteobacteria G Domain of unknown function (DUF3473) - - - - - - - - - - - - DUF3473,Polysacc_deac_1 SYD1_k127_1236413_161 880073.Calab_1562 4.084e-20 105.0 COG2067@1|root,COG2067@2|Bacteria 2|Bacteria I long-chain fatty acid transporting porin activity - - - - - - - - - - - - - SYD1_k127_1236413_105 1123242.JH636435_gene1469 1.699e-59 214.0 COG2148@1|root,COG2148@2|Bacteria,2IX7E@203682|Planctomycetes 203682|Planctomycetes M involved in lipopolysaccharide - - - ko:K03606 ko05111,map05111 - - - ko00000,ko00001 - - - Bac_transf,CoA_binding_3 SYD1_k127_1236413_107 1499967.BAYZ01000054_gene4790 6.599e-56 218.0 COG5000@1|root,COG5000@2|Bacteria,2NQEP@2323|unclassified Bacteria 2|Bacteria T COGs COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - 2.7.13.3 ko:K07709 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_9,sCache_3_2 SYD1_k127_1236413_37 1232410.KI421428_gene1054 2.109e-131 434.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales 28221|Deltaproteobacteria T Domains REC, sigma54 interaction, HTH8 - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_1236413_165 1499967.BAYZ01000182_gene4418 4.231e-18 91.0 COG2980@1|root,COG2980@2|Bacteria,2NQ1I@2323|unclassified Bacteria 2|Bacteria M Evidence 5 No homology to any previously reported sequences lptE GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - ko:K03643 - - - - ko00000,ko02000 1.B.42.1 - iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788 LptE SYD1_k127_1236413_187 572477.Alvin_1290 3.781e-07 61.0 COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,1WWRB@135613|Chromatiales 135613|Chromatiales L DNA polymerase III, delta subunit - - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delt_C,DNA_pol3_delta SYD1_k127_1236413_3 264732.Moth_0568 3.085e-300 952.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,42ER6@68295|Thermoanaerobacterales 186801|Clostridia J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 SYD1_k127_1236413_191 1007103.AFHW01000140_gene3979 2.648e-06 61.0 COG4818@1|root,COG4818@2|Bacteria,1VG59@1239|Firmicutes,4HP4V@91061|Bacilli,26ZHT@186822|Paenibacillaceae 91061|Bacilli S TM2 domain - - - - - - - - - - - - - SYD1_k127_1236413_35 243231.GSU3255 2.351e-132 452.0 COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,42N8E@68525|delta/epsilon subdivisions,2WIY0@28221|Deltaproteobacteria,43UIP@69541|Desulfuromonadales 28221|Deltaproteobacteria G Glycosyl hydrolase family 57 - - - - - - - - - - - - Glyco_hydro_57 SYD1_k127_1236413_196 290315.Clim_1800 0.0001597 52.0 COG1729@1|root,COG1729@2|Bacteria,1FEBS@1090|Chlorobi 1090|Chlorobi S PFAM Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_16,TPR_21,TPR_6 SYD1_k127_1236413_28 926550.CLDAP_29770 4.965e-145 489.0 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - DUF3883,Helicase_C,SNF2_N SYD1_k127_1236413_36 234267.Acid_2834 3.165e-132 448.0 COG1236@1|root,COG1236@2|Bacteria,3Y6U0@57723|Acidobacteria 57723|Acidobacteria J Beta-Casp domain - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL SYD1_k127_1236413_95 477974.Daud_1282 5.36e-67 251.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,260PK@186807|Peptococcaceae 186801|Clostridia D Tyrosine recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase SYD1_k127_1236413_148 1273125.Rrhod_4250 3.699e-26 126.0 COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria,4G0II@85025|Nocardiaceae 201174|Actinobacteria L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N SYD1_k127_1236413_33 379066.GAU_1598 1.929e-136 456.0 COG0322@1|root,COG0322@2|Bacteria,1ZSXE@142182|Gemmatimonadetes 142182|Gemmatimonadetes L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_5,UVR,UvrC_HhH_N SYD1_k127_1236413_188 313628.LNTAR_13572 5.163e-07 55.0 COG0268@1|root,COG0268@2|Bacteria 2|Bacteria J rRNA binding rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p SYD1_k127_1236413_12 243231.GSU1460 1.311e-181 608.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,43TSA@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit SYD1_k127_1236413_136 1192034.CAP_4874 8.135e-34 139.0 COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,2YZXG@29|Myxococcales 28221|Deltaproteobacteria E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N SYD1_k127_1236413_90 330214.NIDE0489 1.735e-71 257.0 COG0329@1|root,COG0329@2|Bacteria,3J0CF@40117|Nitrospirae 40117|Nitrospirae E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS SYD1_k127_1236413_162 518766.Rmar_0462 2.019e-19 104.0 COG2372@1|root,COG2372@2|Bacteria,4PM5M@976|Bacteroidetes,1FIJV@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Bacterial Ig-like domain - - - - - - - - - - - - Big_5,CarboxypepD_reg SYD1_k127_1236413_60 671143.DAMO_0075 8.817e-99 340.0 COG0078@1|root,COG0078@2|Bacteria,2NNWN@2323|unclassified Bacteria 2|Bacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N SYD1_k127_1236413_115 1510531.JQJJ01000010_gene2140 1.042e-44 173.0 COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,2TS7W@28211|Alphaproteobacteria,3K6TH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase SYD1_k127_1236413_7 706587.Desti_4746 2.883e-238 769.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2MQTZ@213462|Syntrophobacterales 28221|Deltaproteobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom SYD1_k127_1236413_0 1379698.RBG1_1C00001G1656 0.0 1191.0 COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria 2|Bacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW SYD1_k127_1236413_127 1379698.RBG1_1C00001G0464 9.679e-40 155.0 COG0170@1|root,COG0170@2|Bacteria,2NQ5M@2323|unclassified Bacteria 2|Bacteria I dolichyl monophosphate biosynthetic process sec59 - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf SYD1_k127_1236413_137 290397.Adeh_1603 3.842e-33 150.0 COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions 1224|Proteobacteria M transglycosylase slt GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 iETEC_1333.ETEC_4747,iPC815.YPO0452 SLT,SLT_L SYD1_k127_1236413_156 459349.CLOAM0891 8.694e-23 115.0 COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria 2|Bacteria S peptidase activity, acting on L-amino acid peptides - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - Big_2,HATPase_c,PQQ_2,PQQ_3,Peptidase_C25,SLH,Y_Y_Y SYD1_k127_1236413_117 227882.SAV_1180 1.456e-42 180.0 COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria 201174|Actinobacteria M PFAM peptidase M6, immune inhibitor A - - - - - - - - - - - - Peptidase_M6 SYD1_k127_1236413_11 880073.Calab_0772 6.152e-189 608.0 COG0519@1|root,COG0519@2|Bacteria,2NNRS@2323|unclassified Bacteria 2|Bacteria F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 ko:K01951,ko:K03790 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002,ko03009 - - iLJ478.TM1820 GATase,GMP_synt_C,NAD_synthase SYD1_k127_1236413_40 1384054.N790_08055 3.571e-125 434.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1X3IH@135614|Xanthomonadales 135614|Xanthomonadales F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS SYD1_k127_1236413_64 234267.Acid_5250 2.193e-94 352.0 COG0152@1|root,COG0152@2|Bacteria,3Y2KX@57723|Acidobacteria 57723|Acidobacteria F PFAM SAICAR synthetase purC - 6.3.2.6,6.3.4.13 ko:K01923,ko:K13713 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt SYD1_k127_1236413_124 646529.Desaci_0870 6.005e-41 158.0 COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,261MS@186807|Peptococcaceae 186801|Clostridia F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS04225 Formyl_trans_N SYD1_k127_1236413_112 1242864.D187_006119 6.407e-48 197.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,42N3S@68525|delta/epsilon subdivisions,2WJ5P@28221|Deltaproteobacteria,2YUX0@29|Myxococcales 28221|Deltaproteobacteria S DNA internalization-related competence protein ComEC Rec2 - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B SYD1_k127_1236413_170 195522.BD01_0726 8.519e-16 92.0 COG0515@1|root,COG3889@1|root,arCOG03264@1|root,arCOG01672@2157|Archaea,arCOG03264@2157|Archaea,arCOG03682@2157|Archaea,2Y2TW@28890|Euryarchaeota,243EY@183968|Thermococci 183968|Thermococci E solute binding protein - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 SYD1_k127_1236413_97 1379698.RBG1_1C00001G1141 4.812e-64 237.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2NP1D@2323|unclassified Bacteria 2|Bacteria M Transglycosylase SLT domain CP_0155 - - ko:K08307,ko:K12204 - - - - ko00000,ko01000,ko01011,ko02044 3.A.7.10.1,3.A.7.9.1 - - LysM,SLT,T4SS_TraI SYD1_k127_1236413_38 383372.Rcas_0946 1.515e-130 460.0 COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi,374V0@32061|Chloroflexia 32061|Chloroflexia H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase SYD1_k127_1236413_51 926550.CLDAP_15250 1.285e-112 377.0 COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase SYD1_k127_1236413_106 945713.IALB_2930 1.893e-57 214.0 COG2067@1|root,COG2067@2|Bacteria 2|Bacteria I long-chain fatty acid transporting porin activity - - - - - - - - - - - - - SYD1_k127_1236413_50 518766.Rmar_1200 6.225e-115 395.0 COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1FIPN@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573,ko:K12585 ko03018,map03018 M00391 - - ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 SYD1_k127_1236413_150 1379698.RBG1_1C00001G1143 3.741e-25 108.0 COG0776@1|root,COG0776@2|Bacteria,2NPU6@2323|unclassified Bacteria 2|Bacteria L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hup_1 - - ko:K03530,ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding SYD1_k127_1236413_92 1379698.RBG1_1C00001G1142 1.053e-69 252.0 COG0616@1|root,COG0616@2|Bacteria,2NPIE@2323|unclassified Bacteria 2|Bacteria OU Peptidase family S49 sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 SYD1_k127_1236413_16 292459.STH248 4.864e-176 565.0 COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia 186801|Clostridia G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N SYD1_k127_1236413_175 1128421.JAGA01000002_gene32 2.779e-14 84.0 COG0095@1|root,COG0095@2|Bacteria,2NPP1@2323|unclassified Bacteria 2|Bacteria H Biotin/lipoate A/B protein ligase family lipM GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB SYD1_k127_1236413_104 1379698.RBG1_1C00001G0112 2.311e-60 228.0 2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SYD1_k127_1236413_75 1379698.RBG1_1C00001G0113 5.955e-86 302.0 28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SYD1_k127_1236413_108 1379698.RBG1_1C00001G0114 9.523e-54 196.0 29ZH8@1|root,30MGZ@2|Bacteria,2NQ83@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_1236413_69 1379698.RBG1_1C00001G0115 2.483e-89 308.0 28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SYD1_k127_1236413_42 1379698.RBG1_1C00001G0120 6.003e-125 410.0 28II6@1|root,2Z8JB@2|Bacteria,2NNT1@2323|unclassified Bacteria 2|Bacteria S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - - SYD1_k127_1236413_5 1379698.RBG1_1C00001G0122 3.906e-262 827.0 COG1070@1|root,COG1070@2|Bacteria,2NP2A@2323|unclassified Bacteria 2|Bacteria G MutL protein - - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N,MutL SYD1_k127_1236413_159 1379698.RBG1_1C00001G0125 4.543e-21 99.0 2EGJW@1|root,3110Q@2|Bacteria,2NS2A@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_1236413_186 1379698.RBG1_1C00001G0126 2.824e-08 62.0 2C451@1|root,2ZRAU@2|Bacteria,2NS2X@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_1236413_20 562970.Btus_0711 5.54e-166 556.0 COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli,27881@186823|Alicyclobacillaceae 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPB - 1.4.4.2 ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - Aminotran_5,GDC-P SYD1_k127_1236413_41 401526.TcarDRAFT_2681 4.989e-125 422.0 COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,4H3B3@909932|Negativicutes 909932|Negativicutes E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P SYD1_k127_1236413_120 1169144.KB911017_gene3782 7.691e-42 174.0 COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,1ZGG0@1386|Bacillus 91061|Bacilli E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate gcvH GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H SYD1_k127_1236413_58 373903.Hore_23440 6.702e-100 338.0 COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,248U7@186801|Clostridia,3WBC4@53433|Halanaerobiales 186801|Clostridia H The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C SYD1_k127_1236413_1 498761.HM1_1297 0.0 1173.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia 186801|Clostridia L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran SYD1_k127_1236413_85 1121406.JAEX01000005_gene3050 2.412e-75 272.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42M0S@68525|delta/epsilon subdivisions,2WITR@28221|Deltaproteobacteria,2M7ZW@213115|Desulfovibrionales 28221|Deltaproteobacteria E PFAM ABC transporter related - - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran SYD1_k127_1236413_110 1408254.T458_07320 1.005e-49 184.0 COG0765@1|root,COG0765@2|Bacteria,1UZTA@1239|Firmicutes,4HEZI@91061|Bacilli 91061|Bacilli E amino acid - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 SYD1_k127_1236413_109 1122603.ATVI01000007_gene1631 4.658e-53 215.0 COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,1RZ89@1236|Gammaproteobacteria,1XBX2@135614|Xanthomonadales 135614|Xanthomonadales ET Ligated ion channel L-glutamate- and glycine-binding site - - - - - - - - - - - - SBP_bac_3 SYD1_k127_1236413_53 1047013.AQSP01000140_gene2536 1.193e-106 359.0 COG0577@1|root,COG0577@2|Bacteria,2NNN0@2323|unclassified Bacteria 2|Bacteria V COGs COG0577 ABC-type antimicrobial peptide transport system permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SYD1_k127_1236413_67 1047013.AQSP01000140_gene2537 2.017e-91 325.0 COG0577@1|root,COG0577@2|Bacteria,2NQMU@2323|unclassified Bacteria 2|Bacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SYD1_k127_1236413_70 1382359.JIAL01000001_gene2865 7.263e-89 331.0 COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria,2JI7R@204432|Acidobacteriia 204432|Acidobacteriia V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SYD1_k127_1236413_65 1379698.RBG1_1C00001G1364 3.341e-93 321.0 COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family macA - - ko:K02005,ko:K15727 - - - - ko00000,ko02000 8.A.1.2.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP SYD1_k127_1236413_178 225937.HP15_451 4.22e-12 79.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,46448@72275|Alteromonadaceae 1236|Gammaproteobacteria MU COG1538 Outer membrane protein tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP SYD1_k127_1236413_189 1047013.AQSP01000057_gene1924 1.013e-06 59.0 2A6YD@1|root,30VTC@2|Bacteria,2NQ0X@2323|unclassified Bacteria 2|Bacteria S Yip1 domain - - - - - - - - - - - - Yip1 SYD1_k127_1236413_183 1121440.AUMA01000003_gene2934 5.619e-10 71.0 COG0810@1|root,COG0810@2|Bacteria,1NDQZ@1224|Proteobacteria,42VIY@68525|delta/epsilon subdivisions,2WRTC@28221|Deltaproteobacteria,2MDBG@213115|Desulfovibrionales 28221|Deltaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C SYD1_k127_1236413_192 309807.SRU_1679 5.476e-06 57.0 COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,1FJBN@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD SYD1_k127_1236413_181 880073.Calab_2425 9.082e-11 74.0 COG0848@1|root,COG0848@2|Bacteria 2|Bacteria U biopolymer transport protein - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD SYD1_k127_1236413_113 880073.Calab_2424 1.899e-47 187.0 COG0811@1|root,COG0811@2|Bacteria,2NPUZ@2323|unclassified Bacteria 2|Bacteria U MotA/TolQ/ExbB proton channel family exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB SYD1_k127_1236413_173 903818.KI912268_gene1642 2.002e-14 82.0 COG0810@1|root,COG0810@2|Bacteria,3Y4BU@57723|Acidobacteria 57723|Acidobacteria M Gram-negative bacterial TonB protein C-terminal - - - - - - - - - - - - TonB_C SYD1_k127_1236413_147 1379698.RBG1_1C00001G1358 4.875e-27 124.0 COG0810@1|root,COG0810@2|Bacteria,2NQ1D@2323|unclassified Bacteria 2|Bacteria M Gram-negative bacterial TonB protein C-terminal - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - CarbopepD_reg_2,TonB_C SYD1_k127_1236413_138 517418.Ctha_2330 2.443e-32 134.0 COG0848@1|root,COG0848@2|Bacteria,1FE26@1090|Chlorobi 1090|Chlorobi U PFAM Biopolymer transport protein ExbD TolR - - - - - - - - - - - - ExbD SYD1_k127_1236413_152 517418.Ctha_2331 1.171e-24 108.0 COG0848@1|root,COG0848@2|Bacteria,1FDZ1@1090|Chlorobi 1090|Chlorobi U Outer membrane transport energization protein ExbD - - - - - - - - - - - - ExbD SYD1_k127_1236413_93 1379698.RBG1_1C00001G1355 1.564e-68 242.0 COG0811@1|root,COG0811@2|Bacteria,2NPUZ@2323|unclassified Bacteria 2|Bacteria U MotA/TolQ/ExbB proton channel family exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB SYD1_k127_1236413_185 469616.FMAG_00123 9.442e-09 61.0 COG1366@1|root,COG1366@2|Bacteria,37AEP@32066|Fusobacteria 32066|Fusobacteria T STAS domain - - - ko:K04749 - - - - ko00000,ko03021 - - - STAS SYD1_k127_1236413_132 1379698.RBG1_1C00001G1353 3.861e-38 166.0 COG0457@1|root,COG0457@2|Bacteria,2NRIR@2323|unclassified Bacteria 2|Bacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_11,TPR_16,TPR_2,TPR_8 SYD1_k127_1236413_163 1123239.KB898623_gene1204 2.535e-19 99.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli 91061|Bacilli P phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 SYD1_k127_1236413_18 330214.NIDE0751 9.219e-175 565.0 COG0017@1|root,COG0017@2|Bacteria 2|Bacteria J Asparaginyl-tRNA synthetase asnS GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon SYD1_k127_1236413_157 215803.DB30_0042 1.987e-22 113.0 COG0457@1|root,COG0457@2|Bacteria,1P92T@1224|Proteobacteria,4331J@68525|delta/epsilon subdivisions,2WYEN@28221|Deltaproteobacteria,2YZFI@29|Myxococcales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - SYD1_k127_1236413_176 351607.Acel_1324 3.826e-13 81.0 COG0457@1|root,COG0457@2|Bacteria 351607.Acel_1324|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - SYD1_k127_1236413_193 1121380.JNIW01000008_gene1616 5.898e-06 59.0 COG0382@1|root,COG0382@2|Bacteria 2|Bacteria H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate ubiA - 2.5.1.133,2.5.1.62 ko:K04040,ko:K20616 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R06284,R09067,R11514,R11517 RC00020 ko00000,ko00001,ko01000,ko01006 - - - UbiA SYD1_k127_1236413_129 1158292.JPOE01000002_gene3152 4.654e-39 158.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,1KKPX@119065|unclassified Burkholderiales 28216|Betaproteobacteria M Glycosyltransferase family 9 (heptosyltransferase) rfaF - - ko:K02841,ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 SYD1_k127_1236413_26 997346.HMPREF9374_0644 2.659e-147 494.0 COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli,27B3G@186824|Thermoactinomycetaceae 91061|Bacilli E Cys/Met metabolism PLP-dependent enzyme kbl GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 SYD1_k127_1236413_44 1382359.JIAL01000001_gene1783 1.336e-120 397.0 COG1063@1|root,COG1063@2|Bacteria,3Y3KU@57723|Acidobacteria,2JIQ4@204432|Acidobacteriia 204432|Acidobacteriia C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate tdh - 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N SYD1_k127_1236413_123 1123072.AUDH01000012_gene3499 5.045e-41 169.0 COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2VFXC@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH D-isomer specific 2-hydroxyacid dehydrogenase - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C SYD1_k127_1236413_134 1125863.JAFN01000001_gene536 3.238e-35 147.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42UES@68525|delta/epsilon subdivisions,2WQD1@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM glycosyl transferase family 9 - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 SYD1_k127_1236413_17 1379698.RBG1_1C00001G1033 4.984e-176 575.0 COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria 2|Bacteria V ABC transporter msbA - - ko:K02021,ko:K06147,ko:K06148,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane,ABC_tran SYD1_k127_1236413_154 278957.ABEA03000070_gene2933 3.601e-23 105.0 2E5IJ@1|root,3309Y@2|Bacteria,46SYV@74201|Verrucomicrobia,3K87A@414999|Opitutae 414999|Opitutae - - - - - - - - - - - - - - - SYD1_k127_1236413_14 404589.Anae109_3687 3.048e-180 584.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2YUGG@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C SYD1_k127_1236413_155 1158146.KB907127_gene1728 4.049e-23 115.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1WWWV@135613|Chromatiales 135613|Chromatiales M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK SYD1_k127_1236413_135 396588.Tgr7_0481 8.276e-35 153.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1WX73@135613|Chromatiales 135613|Chromatiales M PFAM Three-deoxy-D-manno-octulosonic-acid transferase - - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_1,Glycos_transf_N,Kdo SYD1_k127_1236413_102 349124.Hhal_1455 8.469e-61 235.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1WY1X@135613|Chromatiales 135613|Chromatiales M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB - 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB SYD1_k127_1236413_94 56780.SYN_01566 3.346e-67 241.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,2MR8J@213462|Syntrophobacterales 28221|Deltaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold gnnA - - ko:K09949 - - - - ko00000 - - iAF987.Gmet_2352 GFO_IDH_MocA,GFO_IDH_MocA_C SYD1_k127_1236413_79 1122947.FR7_1565 1.242e-80 278.0 COG1043@1|root,COG1043@2|Bacteria,1TQRI@1239|Firmicutes,4H2NG@909932|Negativicutes 909932|Negativicutes M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep,Hexapep_2 SYD1_k127_1236413_39 1379698.RBG1_1C00001G1649 5.916e-128 438.0 COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,2NNYX@2323|unclassified Bacteria 2|Bacteria M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis fabZ GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 ko:K02372,ko:K02535,ko:K13599,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020 M00060,M00083,M00498,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022 - - - FabA,LpxC SYD1_k127_1236413_59 1379698.RBG1_1C00001G1848 1.469e-99 337.0 COG1044@1|root,COG1044@2|Bacteria,2NNSF@2323|unclassified Bacteria 2|Bacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - ic_1306.c0216 Hexapep,Hexapep_2,LpxD SYD1_k127_1236413_146 1379698.RBG1_1C00001G1847 4.886e-28 120.0 COG2825@1|root,COG2825@2|Bacteria,2NQ6C@2323|unclassified Bacteria 2|Bacteria M Outer membrane protein (OmpH-like) ompH - - ko:K06142 - - - - ko00000 - - - OmpH SYD1_k127_1236413_34 1379698.RBG1_1C00001G1846 6.208e-135 469.0 COG4775@1|root,COG4775@2|Bacteria,2NNNW@2323|unclassified Bacteria 2|Bacteria M Surface antigen bamA GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA SYD1_k127_1236413_2 635013.TherJR_0243 2.5e-323 1009.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,26059@186807|Peptococcaceae 186801|Clostridia O Belongs to the ClpA ClpB family clpC - - ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR SYD1_k127_1236413_62 521674.Plim_0763 8.495e-97 336.0 COG3869@1|root,COG3869@2|Bacteria,2IXJG@203682|Planctomycetes 203682|Planctomycetes H Catalyzes the specific phosphorylation of arginine residues in proteins mcsB - 2.7.14.1 ko:K19405 - - R11090 RC00002,RC00203 ko00000,ko01000 - - - ATP-gua_Ptrans SYD1_k127_1236413_111 1536775.H70737_27720 1.881e-48 180.0 COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli,26R52@186822|Paenibacillaceae 91061|Bacilli S protein with conserved CXXC pairs mcsA GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - ko:K19411 - - - - ko00000 - - - UVR SYD1_k127_1236413_96 1221522.B723_21985 5.558e-66 234.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1YPAU@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria V Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner lolD GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778 - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran SYD1_k127_1236413_63 1379698.RBG1_1C00001G0449 2.776e-95 326.0 COG4591@1|root,COG4591@2|Bacteria,2NP18@2323|unclassified Bacteria 2|Bacteria M ABC-type transport system involved in lipoprotein release permease component lolC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - ko:K02004,ko:K09808 ko02010,map02010 M00255,M00258 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.125 - - FtsX,MacB_PCD SYD1_k127_1236413_21 429009.Adeg_1647 8.386e-164 530.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,42EMJ@68295|Thermoanaerobacterales 186801|Clostridia J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon,tRNA_bind SYD1_k127_1236413_23 401526.TcarDRAFT_1563 2.446e-159 527.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4H2AT@909932|Negativicutes 909932|Negativicutes NU Type II IV secretion system protein epsE - - ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N SYD1_k127_1236413_19 269799.Gmet_1939 3.25e-169 550.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43UES@69541|Desulfuromonadales 28221|Deltaproteobacteria F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,GATase_7,Pribosyltran SYD1_k127_1236413_114 1094715.CM001373_gene3315 3.289e-45 189.0 COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,1SVID@1236|Gammaproteobacteria,1JD85@118969|Legionellales 118969|Legionellales F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 SYD1_k127_1236413_13 272624.lpg1678 2.637e-181 594.0 COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1JDPB@118969|Legionellales 118969|Legionellales F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C SYD1_k127_1236413_25 644966.Tmar_1426 1.128e-147 498.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3WCKG@538999|Clostridiales incertae sedis 186801|Clostridia F Adenylosuccinate lyase C-terminus purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 SYD1_k127_1236413_78 379066.GAU_1730 7.587e-82 288.0 COG0265@1|root,COG0265@2|Bacteria,1ZTAM@142182|Gemmatimonadetes 142182|Gemmatimonadetes O Trypsin - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 SYD1_k127_1236413_122 861299.J421_3369 3.402e-41 170.0 COG0101@1|root,COG0101@2|Bacteria,1ZSRZ@142182|Gemmatimonadetes 142182|Gemmatimonadetes J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA - 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 SYD1_k127_1236413_82 443143.GM18_3494 6.068e-79 284.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales 28221|Deltaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase SYD1_k127_1236413_89 880073.Calab_0059 2.385e-72 256.0 COG0673@1|root,COG0673@2|Bacteria,2NQ2X@2323|unclassified Bacteria 2|Bacteria S Oxidoreductase family, C-terminal alpha/beta domain ycjS - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C SYD1_k127_1236413_80 1028307.EAE_08230 2.182e-79 278.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,3X3N2@547|Enterobacter 1236|Gammaproteobacteria T Bacterial regulatory protein, Fis family zraR GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_1236413_68 760568.Desku_1698 1.081e-90 330.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,25ZYS@186807|Peptococcaceae 186801|Clostridia F PFAM AIR synthase related protein purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C SYD1_k127_1236413_101 555088.DealDRAFT_1143 1.046e-61 233.0 COG2206@1|root,COG2206@2|Bacteria,1UJ0B@1239|Firmicutes,25ESZ@186801|Clostridia,42KJX@68298|Syntrophomonadaceae 186801|Clostridia T HD domain - - - - - - - - - - - - GAF_2,HD,HD_5,PAS,PAS_3,PAS_4 SYD1_k127_1236413_74 243231.GSU1113 6.353e-87 308.0 COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,43S1S@69541|Desulfuromonadales 28221|Deltaproteobacteria H PFAM PfkB domain protein - - - - - - - - - - - iAF987.Gmet_2683 PfkB SYD1_k127_1236413_24 584708.Apau_1036 3.574e-148 490.0 COG0018@1|root,COG0018@2|Bacteria,3TA5K@508458|Synergistetes 508458|Synergistetes J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d SYD1_k127_1236413_145 517418.Ctha_0064 4.599e-28 129.0 COG0799@1|root,COG0799@2|Bacteria,1FE3F@1090|Chlorobi 1090|Chlorobi J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS SYD1_k127_1236413_86 1519464.HY22_11685 6.059e-75 264.0 COG0142@1|root,COG0142@2|Bacteria,1FDCJ@1090|Chlorobi 1090|Chlorobi H Belongs to the FPP GGPP synthase family - - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt SYD1_k127_1236413_47 448385.sce1090 4.757e-118 417.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,42N0S@68525|delta/epsilon subdivisions,2WMJK@28221|Deltaproteobacteria,2Z3CT@29|Myxococcales 28221|Deltaproteobacteria H tRNA nucleotidyltransferase domain 2 putative - - 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 - - - HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 SYD1_k127_1236413_126 1379698.RBG1_1C00001G0287 4.739e-40 169.0 COG4191@1|root,COG4191@2|Bacteria 2|Bacteria T Histidine kinase - - 2.7.13.3 ko:K14986 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_9 SYD1_k127_1236413_100 330214.NIDE3218 1.362e-62 224.0 COG0388@1|root,COG0388@2|Bacteria,3J11H@40117|Nitrospirae 40117|Nitrospirae S Carbon-nitrogen hydrolase - - - - - - - - - - - - CN_hydrolase SYD1_k127_1236413_133 246197.MXAN_2999 2.068e-36 159.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2WMQE@28221|Deltaproteobacteria,2YVJ7@29|Myxococcales 28221|Deltaproteobacteria S Belongs to the multicopper oxidase YfiH RL5 family - - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 SYD1_k127_1236413_158 1162668.LFE_1413 9.765e-22 102.0 COG0671@1|root,COG0671@2|Bacteria,3J155@40117|Nitrospirae 40117|Nitrospirae I Acid phosphatase homologues - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2,PMT_2 SYD1_k127_1236413_22 1499967.BAYZ01000011_gene5215 9.198e-162 561.0 COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria 2|Bacteria MU WD40-like Beta Propeller Repeat - - - ko:K03641,ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33,2.C.1.2 - - BSP,Bac_surface_Ag,PD40,Peptidase_MA_2 SYD1_k127_1236413_87 1128421.JAGA01000002_gene587 3.223e-74 275.0 COG0013@1|root,COG0013@2|Bacteria,2NPQB@2323|unclassified Bacteria 2|Bacteria J Threonyl and Alanyl tRNA synthetase second additional domain alaS_2 - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD SYD1_k127_1236413_8 1379698.RBG1_1C00001G1445 1.63e-221 718.0 COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NQSG@2323|unclassified Bacteria 2|Bacteria MU WD40-like Beta Propeller Repeat - - - ko:K03641,ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33,2.C.1.2 - - BSP,Bac_surface_Ag,PD40,Peptidase_MA_2 SYD1_k127_1236413_72 326427.Cagg_1321 2.515e-88 316.0 COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi,375CQ@32061|Chloroflexia 32061|Chloroflexia S PFAM Amidohydrolase 3 - - - - - - - - - - - - Amidohydro_3 SYD1_k127_1236413_167 215803.DB30_0140 7.895e-18 90.0 COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2Z0IS@29|Myxococcales 28221|Deltaproteobacteria P CutA1 divalent ion tolerance protein cutA - - ko:K03926 - - - - ko00000 - - - CutA1 SYD1_k127_1236413_164 693986.MOC_2509 4.622e-19 99.0 COG0438@1|root,COG0438@2|Bacteria,1PPCP@1224|Proteobacteria,2V1V9@28211|Alphaproteobacteria,1JXNU@119045|Methylobacteriaceae 28211|Alphaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4 SYD1_k127_1236413_76 555088.DealDRAFT_2005 2.234e-85 295.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,24BAN@186801|Clostridia 186801|Clostridia G M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 SYD1_k127_1236413_81 867903.ThesuDRAFT_01176 2.781e-79 293.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,248D0@186801|Clostridia 186801|Clostridia G M42 glutamyl aminopeptidase - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - Peptidase_M42 SYD1_k127_1236413_131 411467.BACCAP_02008 3.617e-38 163.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,248D0@186801|Clostridia,267PI@186813|unclassified Clostridiales 186801|Clostridia E M42 glutamyl aminopeptidase celM - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - Peptidase_M42 SYD1_k127_1236413_48 459349.CLOAM1245 7.006e-118 409.0 COG0436@1|root,COG0436@2|Bacteria,2NP0E@2323|unclassified Bacteria 2|Bacteria E Aminotransferase class I and II aspC - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - iHN637.CLJU_RS10450 Aminotran_1_2 SYD1_k127_1236413_179 459349.CLOAM0984 3.124e-11 78.0 COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria 2|Bacteria M Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25 SYD1_k127_1236413_32 1232410.KI421424_gene1794 1.183e-136 472.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria,43TSP@69541|Desulfuromonadales 28221|Deltaproteobacteria C Proton-conducting membrane transporter nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M SYD1_k127_1236413_10 247490.KSU1_D0316 1.749e-193 617.0 COG1008@1|root,COG1008@2|Bacteria,2IX79@203682|Planctomycetes 203682|Planctomycetes C proton-translocating NADH-quinone oxidoreductase, chain M - - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M SYD1_k127_1236413_9 706587.Desti_2759 1.507e-216 695.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,2MS08@213462|Syntrophobacterales 28221|Deltaproteobacteria CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus nuoL-1 - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_C,Proton_antipo_M,Proton_antipo_N SYD1_k127_1236413_143 237368.SCABRO_02000 5.246e-29 126.0 COG0713@1|root,COG0713@2|Bacteria,2J0GU@203682|Planctomycetes 203682|Planctomycetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK - 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 SYD1_k127_1236413_144 237368.SCABRO_02001 2.4e-28 120.0 COG0839@1|root,COG0839@2|Bacteria,2J0MC@203682|Planctomycetes 203682|Planctomycetes C PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 - - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 SYD1_k127_1236413_43 671143.DAMO_2695 1.53e-122 400.0 COG1005@1|root,COG1005@2|Bacteria,2NNTT@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh SYD1_k127_1236413_118 1382306.JNIM01000001_gene3468 5.674e-42 168.0 COG1905@1|root,COG1905@2|Bacteria,2G70Y@200795|Chloroflexi 200795|Chloroflexi C PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit - - 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx SYD1_k127_1236413_125 1125863.JAFN01000001_gene2419 1.451e-40 162.0 COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,42NAR@68525|delta/epsilon subdivisions,2WQB1@28221|Deltaproteobacteria 28221|Deltaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iAF987.Gmet_3353 Complex1_30kDa SYD1_k127_1236413_128 671143.DAMO_2700 1.261e-39 150.0 COG0838@1|root,COG0838@2|Bacteria,2NPTW@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 SYD1_k127_1236413_83 330214.NIDE3119 6.287e-79 274.0 COG0491@1|root,COG0491@2|Bacteria,3J1C9@40117|Nitrospirae 40117|Nitrospirae S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B SYD1_k127_1236413_180 1268303.RHODMAR_2721 5.745e-11 76.0 2AR1Y@1|root,31GAW@2|Bacteria,2HK0E@201174|Actinobacteria,4G7PU@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - SYD1_k127_1236413_140 1297742.A176_05269 3.321e-30 126.0 COG0328@1|root,COG0328@2|Bacteria,1MZD1@1224|Proteobacteria,42UI6@68525|delta/epsilon subdivisions,2WQSU@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Ribonuclease H rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RVT_3 SYD1_k127_1236413_171 1267535.KB906767_gene2786 8.665e-16 87.0 2DB97@1|root,32TX2@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_1236413_45 889378.Spiaf_2857 4.98e-120 396.0 COG0082@1|root,COG0082@2|Bacteria,2J5CX@203691|Spirochaetes 203691|Spirochaetes E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC - 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt SYD1_k127_1236413_71 945713.IALB_0407 2.367e-88 302.0 COG2070@1|root,COG2070@2|Bacteria 2|Bacteria S nitronate monooxygenase activity fabK - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO SYD1_k127_1236413_119 1089551.KE386572_gene3186 5.714e-42 168.0 2DBFU@1|root,2Z90B@2|Bacteria,1PI0M@1224|Proteobacteria,2U90U@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF429) - - - - - - - - - - - - DUF429 SYD1_k127_1236413_103 661478.OP10G_2741 1.971e-60 226.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,GerE SYD1_k127_1236413_91 309801.trd_0178 3.438e-70 246.0 COG0483@1|root,COG0483@2|Bacteria,2G6JD@200795|Chloroflexi,27Y5G@189775|Thermomicrobia 189775|Thermomicrobia G Inositol monophosphatase family - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P SYD1_k127_1236413_166 1336233.JAEH01000007_gene2473 6.429e-18 94.0 COG2350@1|root,COG2350@2|Bacteria,1NCHB@1224|Proteobacteria,1SG2M@1236|Gammaproteobacteria,2QC74@267890|Shewanellaceae 1236|Gammaproteobacteria S YCII-related domain - - - - - - - - - - - - YCII SYD1_k127_1236413_160 1501230.ET33_33275 2.584e-20 107.0 COG0454@1|root,COG0456@2|Bacteria,1VGQ7@1239|Firmicutes,4HQF4@91061|Bacilli,277JP@186822|Paenibacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 SYD1_k127_1236413_15 1191523.MROS_1555 3.819e-177 586.0 COG1132@1|root,COG1132@2|Bacteria 2|Bacteria V (ABC) transporter MdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran SYD1_k127_1236413_27 240015.ACP_0113 2.148e-146 483.0 COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria,2JIBZ@204432|Acidobacteriia 204432|Acidobacteriia V ABC transporter, transmembrane - - - ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran SYD1_k127_1236413_174 234267.Acid_0817 2.123e-14 83.0 COG1579@1|root,COG1579@2|Bacteria,3Y509@57723|Acidobacteria 57723|Acidobacteria S C4-type zinc ribbon domain - - - ko:K07164 - - - - ko00000 - - - zf-RING_7 SYD1_k127_1236413_29 502025.Hoch_6393 9.537e-145 482.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales 28221|Deltaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 SYD1_k127_1236413_55 518766.Rmar_0977 2.405e-101 359.0 COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1FJ4P@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 SYD1_k127_1236413_46 370438.PTH_1939 2.897e-119 415.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,2603C@186807|Peptococcaceae 186801|Clostridia L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr SYD1_k127_1236413_168 290397.Adeh_0718 2.054e-16 81.0 COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,42V6T@68525|delta/epsilon subdivisions,2WRAX@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 SYD1_k127_1236413_169 1280950.HJO_00785 2.912e-16 88.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2TS0N@28211|Alphaproteobacteria,43W5T@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA SYD1_k127_1236413_49 880073.Calab_1434 3.985e-117 395.0 COG0484@1|root,COG0484@2|Bacteria,2NNNG@2323|unclassified Bacteria 2|Bacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG SYD1_k127_1236413_151 518766.Rmar_2126 6.768e-25 120.0 COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,1FJFQ@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE SYD1_k127_1236413_130 518766.Rmar_2127 6.155e-39 159.0 COG1420@1|root,COG1420@2|Bacteria,4PEC8@976|Bacteroidetes,1FIUB@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA SYD1_k127_1236413_88 1121428.DESHY_160013___1 3.706e-73 262.0 COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,260TE@186807|Peptococcaceae 186801|Clostridia H Involved in the biosynthesis of porphyrin-containing compound hemN - - - - - - - - - - - HemN_C,Radical_SAM SYD1_k127_1236413_98 404380.Gbem_1882 1.291e-62 222.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria 28221|Deltaproteobacteria U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 SYD1_k127_1236413_6 518766.Rmar_2045 1.119e-255 806.0 COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1FIPT@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes J Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C SYD1_k127_1236413_172 1379698.RBG1_1C00001G0229 1.072e-14 83.0 2BIY5@1|root,32D6E@2|Bacteria,2NRW7@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_1236413_66 429009.Adeg_0304 6.878e-93 315.0 COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,42ENJ@68295|Thermoanaerobacterales 186801|Clostridia F Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C SYD1_k127_1236413_141 195250.CM001776_gene2386 3.788e-29 125.0 COG0251@1|root,COG0251@2|Bacteria,1G6TD@1117|Cyanobacteria,1H0H6@1129|Synechococcus 1117|Cyanobacteria J endoribonuclease L-PSP tdcF - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Pentapeptide,Ribonuc_L-PSP SYD1_k127_1236413_4 1379698.RBG1_1C00001G0688 2.03e-263 823.0 COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria 2|Bacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iAF987.Gmet_1487 GATase_6,SIS SYD1_k127_1236413_190 666510.ASAC_0747 1.356e-06 51.0 COG1109@1|root,arCOG00767@2157|Archaea,2XPXR@28889|Crenarchaeota 28889|Crenarchaeota G Belongs to the phosphohexose mutase family - - 5.4.2.10,5.4.2.2,5.4.2.8 ko:K01840,ko:K03431,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R02060,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV SYD1_k127_1247690_0 1449126.JQKL01000022_gene130 1.625e-141 465.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,2684D@186813|unclassified Clostridiales 186801|Clostridia U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB SYD1_k127_1247690_6 1262449.CP6013_2439 3.736e-25 112.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,36KP2@31979|Clostridiaceae 186801|Clostridia J Belongs to the bacterial ribosomal protein bS16 family rpsP - - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 SYD1_k127_1247690_8 1158345.JNLL01000001_gene65 8.595e-18 85.0 COG1837@1|root,COG1837@2|Bacteria,2G4BD@200783|Aquificae 200783|Aquificae S Belongs to the UPF0109 family - - - ko:K06960 - - - - ko00000 - - - KH_4 SYD1_k127_1247690_4 264732.Moth_0969 1.274e-32 134.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,42GJV@68295|Thermoanaerobacterales 186801|Clostridia J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM SYD1_k127_1247690_1 1121422.AUMW01000002_gene2175 4.123e-78 269.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,260JP@186807|Peptococcaceae 186801|Clostridia J Belongs to the RNA methyltransferase TrmD family trmD - 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT SYD1_k127_1247690_5 635013.TherJR_2043 6.252e-31 135.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,261ZW@186807|Peptococcaceae 186801|Clostridia J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS - - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 SYD1_k127_1247690_3 107635.AZUO01000001_gene2828 1.287e-51 190.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,36YDE@31993|Methylocystaceae 28211|Alphaproteobacteria L Ribonuclease HII rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII SYD1_k127_1247690_7 405948.SACE_6045 4.227e-20 97.0 COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4E5Y2@85010|Pseudonocardiales 201174|Actinobacteria L Belongs to the UPF0102 family yraN - - ko:K07460 - - - - ko00000 - - - UPF0102 SYD1_k127_1247690_2 1157708.KB907464_gene401 3.944e-72 258.0 COG0707@1|root,COG0707@2|Bacteria,1QU89@1224|Proteobacteria,2VKVF@28216|Betaproteobacteria,4AFFZ@80864|Comamonadaceae 28216|Betaproteobacteria M Monogalactosyldiacylglycerol (MGDG) synthase - - 2.4.1.315,2.4.1.46 ko:K03429,ko:K03715 ko00561,ko01100,map00561,map01100 - R02689,R02691,R04377 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT28 - Glyco_tran_28_C,MGDG_synth SYD1_k127_1247690_9 718252.FP2_28540 0.0007284 46.0 COG1396@1|root,COG1396@2|Bacteria,1UVZY@1239|Firmicutes,24N7C@186801|Clostridia 186801|Clostridia K sequence-specific DNA binding - - - ko:K20391 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 SYD1_k127_1251369_10 1499967.BAYZ01000114_gene2902 7.07e-19 86.0 COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria 2|Bacteria U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY SYD1_k127_1251369_4 1125863.JAFN01000001_gene3315 2.016e-65 232.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2WJH0@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid SYD1_k127_1251369_2 373903.Hore_01380 2.872e-87 306.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3WA6N@53433|Halanaerobiales 186801|Clostridia J TIGRFAM methionine aminopeptidase, type I map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 SYD1_k127_1251369_8 926561.KB900620_gene3180 1.015e-35 137.0 COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,3WBWA@53433|Halanaerobiales 186801|Clostridia J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA - - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a SYD1_k127_1251369_12 880072.Desac_1432 1.283e-10 66.0 COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2WSYK@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 SYD1_k127_1251369_6 1379698.RBG1_1C00001G1571 4.422e-49 180.0 COG0099@1|root,COG0099@2|Bacteria,2NPKH@2323|unclassified Bacteria 2|Bacteria J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 SYD1_k127_1251369_5 370438.PTH_0346 2.449e-55 196.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,261G0@186807|Peptococcaceae 186801|Clostridia J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK - - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 SYD1_k127_1251369_3 1379698.RBG1_1C00001G1569 4.157e-73 252.0 COG0522@1|root,COG0522@2|Bacteria,2NPCC@2323|unclassified Bacteria 2|Bacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 SYD1_k127_1251369_0 1379698.RBG1_1C00001G1568 2.398e-116 383.0 COG0202@1|root,COG0202@2|Bacteria,2NNQQ@2323|unclassified Bacteria 2|Bacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L SYD1_k127_1251369_9 865861.AZSU01000001_gene49 1.617e-33 137.0 COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,36IQ8@31979|Clostridiaceae 186801|Clostridia J Ribosomal protein L17 rplQ - - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 SYD1_k127_1251369_7 521045.Kole_1995 3.677e-44 181.0 COG1649@1|root,COG1649@2|Bacteria,2GCSB@200918|Thermotogae 200918|Thermotogae S Glycosyl hydrolase-like 10 - - - - - - - - - - - - GHL10 SYD1_k127_1251369_11 1382304.JNIL01000001_gene794 1.629e-12 78.0 COG0730@1|root,COG0730@2|Bacteria,1TQFD@1239|Firmicutes,4HG35@91061|Bacilli,278AW@186823|Alicyclobacillaceae 91061|Bacilli S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE SYD1_k127_1251369_1 1356852.N008_10405 8.726e-105 350.0 COG1002@1|root,COG1002@2|Bacteria,4NFKA@976|Bacteroidetes,47KR1@768503|Cytophagia 976|Bacteroidetes V Type II restriction enzyme, methylase subunits - - - - - - - - - - - - N6_Mtase SYD1_k127_1397486_4 1370122.JHXQ01000004_gene2497 4.471e-15 88.0 COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,2TUFD@28211|Alphaproteobacteria,4B7NU@82115|Rhizobiaceae 28211|Alphaproteobacteria S protein conserved in bacteria - - - ko:K09798 - - - - ko00000 - - - Polysacc_deac_2 SYD1_k127_1397486_1 671143.DAMO_1558 3.883e-63 241.0 COG0854@1|root,COG0854@2|Bacteria,2NPFY@2323|unclassified Bacteria 2|Bacteria H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2564,iAF987.Gmet_1885,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390 PdxJ SYD1_k127_1397486_3 1198114.AciX9_2489 2.359e-26 126.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity wcoG - - - - - - - - - - - DUF5122,Laminin_G_3,PKD SYD1_k127_1397486_6 1191523.MROS_0081 3.352e-07 64.0 COG0737@1|root,COG3291@1|root,COG0737@2|Bacteria,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity xynX5 - 3.2.1.4,3.2.1.8 ko:K01179,ko:K01181 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - Beta_helix,IgGFc_binding,Metallophos,PKD,SLH SYD1_k127_1397486_2 1220535.IMCC14465_06040 1.469e-52 209.0 COG2182@1|root,COG2182@2|Bacteria,1MU3H@1224|Proteobacteria,2U0ZI@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Extracellular solute-binding protein - - - - - - - - - - - - - SYD1_k127_1397486_0 1254432.SCE1572_30795 7.859e-126 442.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MX4K@1224|Proteobacteria,42WVW@68525|delta/epsilon subdivisions,2X77J@28221|Deltaproteobacteria,2YUN6@29|Myxococcales 28221|Deltaproteobacteria P Outer membrane protein beta-barrel family - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec SYD1_k127_1397486_5 1519464.HY22_04880 1.749e-08 67.0 2ES4T@1|root,33JPM@2|Bacteria,1FFC2@1090|Chlorobi 1090|Chlorobi - - - - - - - - - - - - - - - SYD1_k127_1490935_1 1114964.L485_03275 8.394e-94 317.0 COG3667@1|root,COG3667@2|Bacteria,1R6TA@1224|Proteobacteria,2U52R@28211|Alphaproteobacteria,2K3M1@204457|Sphingomonadales 204457|Sphingomonadales P copper resistance - - - - - - - - - - - - - SYD1_k127_1490935_3 1123511.KB905840_gene695 2.638e-30 128.0 COG1309@1|root,COG1309@2|Bacteria,1UZ9I@1239|Firmicutes,4H48T@909932|Negativicutes 909932|Negativicutes K Bacterial transcriptional repressor C-terminal - - - - - - - - - - - - TetR_C_11,TetR_N SYD1_k127_1490935_0 296591.Bpro_1506 7.623e-230 719.0 COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2VI8J@28216|Betaproteobacteria,4AD4J@80864|Comamonadaceae 28216|Betaproteobacteria C Berberine and berberine like - - - - - - - - - - - - BBE,FAD_binding_4 SYD1_k127_1490935_2 247490.KSU1_C0449 4.874e-66 247.0 COG2931@1|root,COG2931@2|Bacteria 2|Bacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - Cadherin_3,DUF4347,Peptidase_S8 SYD1_k127_1490935_4 880073.Calab_2401 1.764e-11 77.0 COG2374@1|root,COG2374@2|Bacteria,2NRB5@2323|unclassified Bacteria 2|Bacteria G Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - Endonuclease_1,Exo_endo_phos,FlgD_ig,LTD SYD1_k127_1490935_5 247490.KSU1_C0449 5.313e-05 55.0 COG2931@1|root,COG2931@2|Bacteria 2|Bacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - Cadherin_3,DUF4347,Peptidase_S8 SYD1_k127_1545253_3 264732.Moth_1955 2.766e-149 486.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,42EKB@68295|Thermoanaerobacterales 186801|Clostridia E PFAM aminotransferase, class I - - 2.6.1.1 ko:K00812,ko:K10907 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 SYD1_k127_1545253_7 1232410.KI421413_gene725 3.153e-93 332.0 COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,42M16@68525|delta/epsilon subdivisions,2WM0V@28221|Deltaproteobacteria,43UMW@69541|Desulfuromonadales 28221|Deltaproteobacteria E Amino acid kinase family cpkA - 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 - R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 - - - AA_kinase SYD1_k127_1545253_14 272844.PAB0303 2.744e-50 199.0 COG3845@1|root,arCOG00186@2157|Archaea,2XUEG@28890|Euryarchaeota,242JT@183968|Thermococci 183968|Thermococci E ATPases associated with a variety of cellular activities - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran SYD1_k127_1545253_24 926569.ANT_27900 3.633e-09 70.0 COG4603@1|root,COG4603@2|Bacteria,2G6MU@200795|Chloroflexi 200795|Chloroflexi S Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 SYD1_k127_1545253_21 1242864.D187_009330 1.283e-27 130.0 COG1287@1|root,COG1287@2|Bacteria 2|Bacteria S oligosaccharyl transferase activity - - - - - - - - - - - - - SYD1_k127_1545253_19 497964.CfE428DRAFT_4532 2.46e-38 166.0 COG0737@1|root,COG0737@2|Bacteria,46TFI@74201|Verrucomicrobia 74201|Verrucomicrobia C Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554 SYD1_k127_1545253_15 926550.CLDAP_13010 1.727e-47 183.0 COG3629@1|root,COG3629@2|Bacteria 2|Bacteria K phosphorelay signal transduction system - - - - - - - - - - - - AAA_16,Abhydrolase_1,BTAD,TPR_12,Trans_reg_C SYD1_k127_1545253_25 398512.JQKC01000015_gene4663 1.476e-08 65.0 COG5184@1|root,COG5337@1|root,COG5184@2|Bacteria,COG5337@2|Bacteria,1TRAW@1239|Firmicutes,24AQY@186801|Clostridia,3WI9B@541000|Ruminococcaceae 186801|Clostridia M Fn3 associated - - - - - - - - - - - - CHB_HEX_C_1,CotH,Fn3_assoc,LTD SYD1_k127_1545253_23 926560.KE387023_gene1798 1.11e-11 76.0 COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1WKSF@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T Bacterial transcriptional activator domain - - - - - - - - - - - - AAA_16,BTAD,TPR_12 SYD1_k127_1545253_4 926550.CLDAP_04870 2.457e-115 398.0 COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi 200795|Chloroflexi G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH SYD1_k127_1545253_12 1174528.JH992898_gene3679 1.147e-55 200.0 COG0662@1|root,COG0662@2|Bacteria,1GAI7@1117|Cyanobacteria 1117|Cyanobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 SYD1_k127_1545253_1 1191523.MROS_2800 1.833e-229 720.0 COG0334@1|root,COG0334@2|Bacteria 2|Bacteria E glutamate dehydrogenase [NAD(P)+] activity gluD GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 ko:K00260,ko:K00261,ko:K00262 ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN678.gdhA ELFV_dehydrog,ELFV_dehydrog_N SYD1_k127_1545253_2 1499967.BAYZ01000119_gene3216 7.666e-192 637.0 COG0574@1|root,COG0574@2|Bacteria,2NQHP@2323|unclassified Bacteria 2|Bacteria G Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - NTP_transf_2,PPDK_N,Response_reg SYD1_k127_1545253_0 1191523.MROS_2798 0.0 1157.0 COG0574@1|root,COG0574@2|Bacteria 2|Bacteria G Belongs to the PEP-utilizing enzyme family - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - NTP_transf_2,PPDK_N,Response_reg SYD1_k127_1545253_6 1499967.BAYZ01000119_gene3214 1.379e-98 330.0 COG2129@1|root,COG2129@2|Bacteria 2|Bacteria L metallophosphoesterase - - - ko:K07096 - - - - ko00000 - - - Metallophos,Metallophos_2,Metallophos_3 SYD1_k127_1545253_20 382245.ASA_0977 1.201e-29 124.0 2DZND@1|root,32VEJ@2|Bacteria,1N2ZR@1224|Proteobacteria,1S9ST@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - NIPSNAP SYD1_k127_1545253_16 909613.UO65_5371 1.612e-45 171.0 COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4E2R0@85010|Pseudonocardiales 201174|Actinobacteria O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03664 - - - - ko00000 - - - SmpB SYD1_k127_1545253_22 187303.BN69_0783 2.336e-14 87.0 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2U0K2@28211|Alphaproteobacteria,36XV8@31993|Methylocystaceae 28211|Alphaproteobacteria M Ami_3 amiC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3 SYD1_k127_1545253_26 864563.HMPREF9166_0753 6.093e-08 66.0 COG5401@1|root,COG5401@2|Bacteria,1V64H@1239|Firmicutes,4H4G2@909932|Negativicutes 909932|Negativicutes S Sporulation and spore germination - - - - - - - - - - - - Germane SYD1_k127_1545253_10 1232410.KI421428_gene1046 1.206e-65 236.0 COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,43TAQ@69541|Desulfuromonadales 28221|Deltaproteobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - iAF987.Gmet_0547 Asp_Glu_race SYD1_k127_1545253_8 1122919.KB905549_gene1978 4.542e-85 293.0 COG0689@1|root,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,4HBH3@91061|Bacilli,26RZT@186822|Paenibacillaceae 91061|Bacilli J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - Ham1p_like,RNase_PH,RNase_PH_C SYD1_k127_1545253_17 1121468.AUBR01000001_gene469 7.391e-45 179.0 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,42GAD@68295|Thermoanaerobacterales 186801|Clostridia F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like SYD1_k127_1545253_13 710111.FraQA3DRAFT_4963 1.558e-52 194.0 COG0504@1|root,COG0504@2|Bacteria,2I8KR@201174|Actinobacteria 201174|Actinobacteria F Glutamine amidotransferase class-I - - - - - - - - - - - - GATase SYD1_k127_1545253_9 234267.Acid_1799 4.125e-81 298.0 COG0384@1|root,COG0384@2|Bacteria,3Y7JN@57723|Acidobacteria 57723|Acidobacteria S PFAM Phenazine biosynthesis PhzC PhzF protein - - - - - - - - - - - - PhzC-PhzF SYD1_k127_1545253_5 1123290.AUDQ01000016_gene843 1.248e-105 370.0 COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,26ESA@186818|Planococcaceae 91061|Bacilli E Peptidase dimerisation domain dapE_3 - 3.5.1.16,3.5.1.18 ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00669,R02734,R09107 RC00064,RC00090,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 SYD1_k127_1545253_18 483219.LILAB_03280 1.36e-42 160.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2YV81@29|Myxococcales 28221|Deltaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB SYD1_k127_1545253_11 335543.Sfum_0219 4.031e-58 217.0 COG0457@1|root,COG3118@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42XTF@68525|delta/epsilon subdivisions,2WSZG@28221|Deltaproteobacteria,2MRX9@213462|Syntrophobacterales 28221|Deltaproteobacteria O Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest SYD1_k127_1792779_5 42256.RradSPS_0598 3.11e-71 252.0 COG2514@1|root,COG2514@2|Bacteria,2GN1X@201174|Actinobacteria,4CSUF@84995|Rubrobacteria 84995|Rubrobacteria S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase SYD1_k127_1792779_3 861299.J421_4169 1.961e-81 289.0 COG0531@1|root,COG0531@2|Bacteria,1ZSQW@142182|Gemmatimonadetes 142182|Gemmatimonadetes E Amino acid permease - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 SYD1_k127_1792779_6 215803.DB30_8469 1.451e-69 258.0 COG1729@1|root,COG1729@2|Bacteria,1N780@1224|Proteobacteria,42V4V@68525|delta/epsilon subdivisions,2WR6U@28221|Deltaproteobacteria,2YW0N@29|Myxococcales 28221|Deltaproteobacteria S Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - - - - - - - - - - - SYD1_k127_1792779_12 103733.JNYO01000015_gene3502 5.42e-26 123.0 COG0477@1|root,COG2814@2|Bacteria,2I8QF@201174|Actinobacteria,4EEFP@85010|Pseudonocardiales 201174|Actinobacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1,MFS_3 SYD1_k127_1792779_15 1267534.KB906755_gene4571 2.429e-11 72.0 COG2318@1|root,COG2318@2|Bacteria,3Y4HD@57723|Acidobacteria,2JJ7B@204432|Acidobacteriia 204432|Acidobacteriia S DinB family - - - - - - - - - - - - DinB SYD1_k127_1792779_10 1379698.RBG1_1C00001G0336 1.248e-38 159.0 COG5588@1|root,COG5588@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1326) - - - - - - - - - - - - DUF1326 SYD1_k127_1792779_2 1254432.SCE1572_15545 9.836e-87 301.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,437Y3@68525|delta/epsilon subdivisions,2X380@28221|Deltaproteobacteria,2YURY@29|Myxococcales 28221|Deltaproteobacteria E aminotransferase class I and II - - - - - - - - - - - - Aminotran_1_2 SYD1_k127_1792779_14 56110.Oscil6304_0926 1.937e-18 89.0 COG1950@1|root,COG1950@2|Bacteria,1G7RB@1117|Cyanobacteria,1HC6H@1150|Oscillatoriales 1117|Cyanobacteria S PFAM membrane protein of - - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 SYD1_k127_1792779_9 326427.Cagg_1865 2.397e-55 204.0 COG0325@1|root,COG0325@2|Bacteria,2G6F1@200795|Chloroflexi,375I2@32061|Chloroflexia 32061|Chloroflexia S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis - - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N SYD1_k127_1792779_18 1123229.AUBC01000003_gene2203 2.913e-09 62.0 COG1872@1|root,COG1872@2|Bacteria 2|Bacteria I DUF167 - - - ko:K09131 - - - - ko00000 - - - DUF167 SYD1_k127_1792779_1 1123508.JH636439_gene936 8.272e-93 317.0 COG0005@1|root,COG0005@2|Bacteria,2IX9R@203682|Planctomycetes 203682|Planctomycetes F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate - - 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 SYD1_k127_1792779_0 1379698.RBG1_1C00001G0103 0.0 1083.0 COG0060@1|root,COG0060@2|Bacteria,2NNT5@2323|unclassified Bacteria 2|Bacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 SYD1_k127_1792779_11 1379270.AUXF01000005_gene662 3.395e-33 149.0 COG1734@1|root,COG1734@2|Bacteria,1ZTP9@142182|Gemmatimonadetes 142182|Gemmatimonadetes T Prokaryotic dksA/traR C4-type zinc finger - - - - - - - - - - - - zf-dskA_traR SYD1_k127_1792779_13 938289.CAJN020000002_gene663 5.686e-24 113.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia 186801|Clostridia MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 SYD1_k127_1792779_4 867903.ThesuDRAFT_01638 2.628e-78 274.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,3WCGP@538999|Clostridiales incertae sedis 186801|Clostridia J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 SYD1_k127_1792779_16 1048834.TC41_2139 6.126e-11 74.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes 1239|Firmicutes L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX SYD1_k127_1792779_7 290512.Paes_2275 2.23e-63 241.0 COG1559@1|root,COG1559@2|Bacteria,1FDN4@1090|Chlorobi 1090|Chlorobi S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG SYD1_k127_1792779_8 1343740.M271_02635 7.201e-60 233.0 COG1606@1|root,COG1606@2|Bacteria,2GPA1@201174|Actinobacteria 201174|Actinobacteria S PFAM ExsB family protein - - - ko:K06864 - - - - ko00000 - - - Asn_synthase,NAD_synthase,QueC SYD1_k127_1792779_19 1408823.AXUS01000073_gene990 6.318e-05 45.0 2DR59@1|root,33A7S@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_179585_0 869210.Marky_0750 2.039e-117 397.0 COG0380@1|root,COG0380@2|Bacteria,1WI3G@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G alpha,alpha-trehalose-phosphate synthase - - 2.4.1.15,2.4.1.347 ko:K00697 ko00500,ko01100,map00500,map01100 - R02737 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 - GT20 - Glyco_transf_20 SYD1_k127_1866316_8 1267535.KB906767_gene5535 8.627e-39 166.0 COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria 57723|Acidobacteria T Inner membrane component of T3SS, cytoplasmic domain - - - - - - - - - - - - FHA,GAF_3,SpoIIE SYD1_k127_1866316_2 526227.Mesil_0605 1.392e-120 396.0 COG0346@1|root,COG0346@2|Bacteria,1WICF@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E glyoxalase bleomycin resistance protein dioxygenase - - - ko:K15975 - - - - ko00000 - - - Glyoxalase SYD1_k127_1866316_1 1192034.CAP_2782 1.23e-209 669.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MCF@68525|delta/epsilon subdivisions,2WJRK@28221|Deltaproteobacteria,2YYUX@29|Myxococcales 28221|Deltaproteobacteria I AMP-binding enzyme C-terminal domain bamY - 6.2.1.25 ko:K04110 ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120 - R01422 RC00004,RC00174 ko00000,ko00001,ko01000 - - iAF987.Gmet_2143 AMP-binding,AMP-binding_C SYD1_k127_1866316_5 502025.Hoch_5093 2.668e-91 308.0 COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WIN0@28221|Deltaproteobacteria,2Z10D@29|Myxococcales 28221|Deltaproteobacteria S Creatinine amidohydrolase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase SYD1_k127_1866316_7 502025.Hoch_4887 2.009e-49 196.0 COG1028@1|root,COG1028@2|Bacteria,1MUS7@1224|Proteobacteria,43AR8@68525|delta/epsilon subdivisions,2X658@28221|Deltaproteobacteria,2Z39A@29|Myxococcales 28221|Deltaproteobacteria IQ NAD dependent epimerase/dehydratase family - - - - - - - - - - - - adh_short,adh_short_C2 SYD1_k127_1866316_9 448385.sce2000 8.158e-30 135.0 COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,434U0@68525|delta/epsilon subdivisions,2WZ4Y@28221|Deltaproteobacteria,2Z1C7@29|Myxococcales 28221|Deltaproteobacteria J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP SYD1_k127_1866316_6 1254432.SCE1572_12185 1.911e-83 284.0 COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,42QU2@68525|delta/epsilon subdivisions,2WMSF@28221|Deltaproteobacteria,2YYYW@29|Myxococcales 28221|Deltaproteobacteria I enoyl-CoA hydratase - - - - - - - - - - - - ECH_1 SYD1_k127_1866316_4 1380394.JADL01000017_gene522 1.719e-92 328.0 COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2TTX8@28211|Alphaproteobacteria,2JPUP@204441|Rhodospirillales 204441|Rhodospirillales I Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N SYD1_k127_1866316_0 1254432.SCE1572_46245 8.56e-312 991.0 COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WK05@28221|Deltaproteobacteria,2YZMG@29|Myxococcales 28221|Deltaproteobacteria C NADH:flavin oxidoreductase / NADH oxidase family - - 1.14.13.40 ko:K09461 ko00627,ko01120,map00627,map01120 - R03998,R03999 RC00244 ko00000,ko00001,ko01000 - - - FAD_binding_3,Oxidored_FMN SYD1_k127_1866316_3 1128421.JAGA01000002_gene1518 9.687e-105 346.0 COG3483@1|root,COG3483@2|Bacteria 2|Bacteria E tryptophan 2,3-dioxygenase activity kynA GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 - - - Trp_dioxygenase SYD1_k127_1866316_10 234267.Acid_5940 2.418e-14 73.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria 57723|Acidobacteria KLTU WD40 domain protein beta Propeller - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase SYD1_k127_19863_25 1541065.JRFE01000007_gene5101 1.143e-38 152.0 COG2242@1|root,COG2242@2|Bacteria,1GA6X@1117|Cyanobacteria 1117|Cyanobacteria H Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 SYD1_k127_19863_17 82654.Pse7367_3811 2.856e-61 225.0 COG4641@1|root,COG4641@2|Bacteria,1GDSG@1117|Cyanobacteria 1117|Cyanobacteria S Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_2 SYD1_k127_19863_33 690850.Desaf_0729 1.154e-27 131.0 COG0463@1|root,COG0463@2|Bacteria,1QVXC@1224|Proteobacteria,43CPH@68525|delta/epsilon subdivisions,2X7WS@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 SYD1_k127_19863_38 666685.R2APBS1_0663 9.097e-05 55.0 COG2244@1|root,COG2244@2|Bacteria,1MV5E@1224|Proteobacteria,1RP0A@1236|Gammaproteobacteria,1X5DP@135614|Xanthomonadales 135614|Xanthomonadales U biosynthesis protein - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_3 SYD1_k127_19863_8 1131269.AQVV01000003_gene753 1.522e-107 366.0 COG2148@1|root,COG2148@2|Bacteria 2|Bacteria M undecaprenyl-phosphate glucose phosphotransferase activity wcaJ - - ko:K03606 ko05111,map05111 - - - ko00000,ko00001 - - - Bac_transf,CoA_binding_3 SYD1_k127_19863_29 1128421.JAGA01000002_gene312 9.765e-32 144.0 COG0859@1|root,COG0859@2|Bacteria 2|Bacteria M ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - ko:K02843,ko:K02849 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 SYD1_k127_19863_26 1121468.AUBR01000031_gene1280 2.634e-38 159.0 COG0438@1|root,COG0438@2|Bacteria,1VC02@1239|Firmicutes,24NFM@186801|Clostridia,42I1K@68295|Thermoanaerobacterales 186801|Clostridia M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4 SYD1_k127_19863_34 1267535.KB906767_gene105 7.985e-23 112.0 COG3307@1|root,COG3307@2|Bacteria,3Y67G@57723|Acidobacteria 57723|Acidobacteria M O-antigen ligase like membrane protein - - - - - - - - - - - - Wzy_C SYD1_k127_19863_37 1380390.JIAT01000010_gene3953 5.472e-12 78.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - PMT_2 SYD1_k127_19863_4 671143.DAMO_0912 2.334e-126 412.0 COG0451@1|root,COG0451@2|Bacteria,2NPS7@2323|unclassified Bacteria 2|Bacteria GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase SYD1_k127_19863_32 1185876.BN8_00664 1.093e-27 130.0 COG1216@1|root,COG1216@2|Bacteria,4NJSE@976|Bacteroidetes,47YAA@768503|Cytophagia 976|Bacteroidetes M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 SYD1_k127_19863_19 517418.Ctha_2664 1.348e-55 219.0 COG0438@1|root,COG0438@2|Bacteria,1FEE3@1090|Chlorobi 1090|Chlorobi H PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 SYD1_k127_19863_35 1453500.AT05_07470 1.561e-21 109.0 COG3307@1|root,COG3307@2|Bacteria,4NMYT@976|Bacteroidetes 976|Bacteroidetes M O-Antigen ligase - - - - - - - - - - - - Wzy_C SYD1_k127_19863_23 269799.Gmet_2183 3.092e-42 173.0 COG3206@1|root,COG3206@2|Bacteria,1QUY4@1224|Proteobacteria,42RD1@68525|delta/epsilon subdivisions,2WMV4@28221|Deltaproteobacteria,43T3D@69541|Desulfuromonadales 28221|Deltaproteobacteria M PFAM lipopolysaccharide biosynthesis - - - - - - - - - - - - GNVR,Wzz SYD1_k127_19863_27 518766.Rmar_2624 8.452e-34 150.0 COG1596@1|root,COG1596@2|Bacteria,4P33T@976|Bacteroidetes 976|Bacteroidetes M Polysaccharide biosynthesis/export protein - - - - - - - - - - - - Poly_export,SLBB SYD1_k127_19863_30 666509.RCA23_c07090 2.636e-29 133.0 COG2244@1|root,COG2244@2|Bacteria,1MV5E@1224|Proteobacteria,2U2E7@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Membrane protein involved in the export of O-antigen and teichoic acid - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C SYD1_k127_19863_7 479434.Sthe_0968 9.882e-116 384.0 COG1088@1|root,COG1088@2|Bacteria,2G5KR@200795|Chloroflexi,27XGB@189775|Thermomicrobia 189775|Thermomicrobia M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily - - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd SYD1_k127_19863_18 1499967.BAYZ01000196_gene3077 3.01e-57 218.0 COG1898@1|root,COG1898@2|Bacteria,2NP7U@2323|unclassified Bacteria 2|Bacteria M dTDP-4-dehydrorhamnose 3,5-epimerase - - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom SYD1_k127_19863_1 1121033.AUCF01000009_gene1086 4.504e-146 474.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,2JPVB@204441|Rhodospirillales 204441|Rhodospirillales M Belongs to the UDP-glucose GDP-mannose dehydrogenase family rkpK - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N SYD1_k127_19863_16 1117108.PAALTS15_24215 4.14e-64 233.0 COG1089@1|root,COG1089@2|Bacteria,1UJFF@1239|Firmicutes,4HF5Y@91061|Bacilli,275YJ@186822|Paenibacillaceae 91061|Bacilli M Polysaccharide biosynthesis protein - - 1.1.1.281 ko:K15856 ko00051,ko00520,map00051,map00520 - R03397,R03399 RC00182 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd SYD1_k127_19863_3 1047013.AQSP01000138_gene1042 6.597e-130 435.0 COG1089@1|root,COG1089@2|Bacteria,2NP6U@2323|unclassified Bacteria 2|Bacteria M Polysaccharide biosynthesis protein wcbK - 1.1.1.281,4.2.1.47 ko:K01711,ko:K15856 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888,R03397,R03399 RC00182,RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd SYD1_k127_19863_21 1267533.KB906736_gene889 3.09e-46 187.0 COG0284@1|root,COG0284@2|Bacteria,3Y2XD@57723|Acidobacteria,2JIQY@204432|Acidobacteriia 204432|Acidobacteriia F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF - 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase SYD1_k127_19863_12 316067.Geob_2780 5.091e-88 316.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,43TBH@69541|Desulfuromonadales 28221|Deltaproteobacteria F Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 ko:K00254,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01868,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh SYD1_k127_19863_24 264732.Moth_2128 1.335e-41 173.0 COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,42GKK@68295|Thermoanaerobacterales 186801|Clostridia C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( pyrK - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - - DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 SYD1_k127_19863_31 880073.Calab_3481 4.422e-28 133.0 COG1729@1|root,COG1729@2|Bacteria,2NPUR@2323|unclassified Bacteria 2|Bacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 SYD1_k127_19863_2 886293.Sinac_3038 6.127e-135 458.0 COG0044@1|root,COG0044@2|Bacteria,2IWS9@203682|Planctomycetes 203682|Planctomycetes F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 SYD1_k127_19863_6 485916.Dtox_2355 4.834e-121 405.0 COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,260AV@186807|Peptococcaceae 186801|Clostridia F Belongs to the ATCase OTCase family pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N SYD1_k127_19863_14 498761.HM1_2105 7.294e-75 256.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia 186801|Clostridia F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - iHN637.CLJU_RS05275 Pribosyltran SYD1_k127_19863_10 886293.Sinac_6796 8.215e-102 368.0 COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,2IX8E@203682|Planctomycetes 203682|Planctomycetes O PA domain - - - - - - - - - - - - PA,PD40,PDZ_2,Peptidase_M28 SYD1_k127_19863_9 1254432.SCE1572_10300 5.659e-103 372.0 COG0823@1|root,COG0823@2|Bacteria,1QW3I@1224|Proteobacteria,42YA5@68525|delta/epsilon subdivisions,2WU6I@28221|Deltaproteobacteria,2Z3J0@29|Myxococcales 28221|Deltaproteobacteria U WD40-like Beta Propeller Repeat - - - - - - - - - - - - PD40 SYD1_k127_19863_36 913865.DOT_5802 4.544e-16 88.0 2E41I@1|root,33BYF@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_19863_22 1034345.CAEM01000058_gene412 1.05e-43 184.0 COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4CUE1@84998|Coriobacteriia 84998|Coriobacteriia P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,DUF87 SYD1_k127_19863_11 335543.Sfum_2531 2.621e-92 327.0 COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria,2MRAV@213462|Syntrophobacterales 28221|Deltaproteobacteria S Belongs to the LarC family - - 4.99.1.12 ko:K09121 - - - - ko00000,ko01000 - - - DUF111 SYD1_k127_19863_15 269799.Gmet_0193 2.545e-66 242.0 COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria,43U0V@69541|Desulfuromonadales 28221|Deltaproteobacteria S AIR carboxylase - - - ko:K06898 - - - - ko00000 - - - AIRC SYD1_k127_19863_13 1064535.MELS_0135 5.223e-86 298.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4H37S@909932|Negativicutes 909932|Negativicutes H Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - - - - - - - - - - Dus SYD1_k127_19863_5 459349.CLOAM0355 2.122e-122 412.0 COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria 2|Bacteria M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S41 SYD1_k127_19863_20 338966.Ppro_1665 1.254e-50 202.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WNES@28221|Deltaproteobacteria,43U3M@69541|Desulfuromonadales 28221|Deltaproteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin SYD1_k127_19863_0 1379698.RBG1_1C00001G1837 5.455e-188 608.0 COG1260@1|root,COG1260@2|Bacteria,2NNVE@2323|unclassified Bacteria 2|Bacteria I Myo-inositol-1-phosphate synthase ino1 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 ko:K01858 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 - R07324 RC01804 ko00000,ko00001,ko01000 - - - Inos-1-P_synth SYD1_k127_19863_28 1382306.JNIM01000001_gene4120 1.946e-33 139.0 COG0558@1|root,COG0558@2|Bacteria,2G6RT@200795|Chloroflexi 200795|Chloroflexi I Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf SYD1_k127_2235009_11 1123278.KB893615_gene5179 1.417e-90 323.0 COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes,47PBP@768503|Cytophagia 976|Bacteroidetes G NHL repeat - - - - - - - - - - - - NHL SYD1_k127_2235009_30 1142394.PSMK_14340 2.068e-06 61.0 COG4970@1|root,COG4970@2|Bacteria,2J1P5@203682|Planctomycetes 203682|Planctomycetes NU Prokaryotic N-terminal methylation motif - - - ko:K02457 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspH,N_methyl SYD1_k127_2235009_27 181119.XP_005528667.1 1.679e-20 107.0 28K3T@1|root,2QSIA@2759|Eukaryota,3974K@33154|Opisthokonta,3BBX0@33208|Metazoa,3CV1I@33213|Bilateria,485N6@7711|Chordata,4962A@7742|Vertebrata,4GM0F@8782|Aves 33208|Metazoa S Transmembrane protein 260 TMEM260 - - - - - - - - - - - DUF2723 SYD1_k127_2235009_29 511051.CSE_14670 6.44e-17 88.0 COG4968@1|root,COG4968@2|Bacteria 2|Bacteria NU Prokaryotic N-terminal methylation motif pilA GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - ko:K02650,ko:K02655 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl,Pilin_PilA SYD1_k127_2235009_13 237368.SCABRO_00279 2.734e-88 305.0 COG1459@1|root,COG1459@2|Bacteria,2IYHA@203682|Planctomycetes 203682|Planctomycetes U Type II secretion system (T2SS), protein F - - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF SYD1_k127_2235009_1 401526.TcarDRAFT_1563 8.104e-154 506.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4H2AT@909932|Negativicutes 909932|Negativicutes NU Type II IV secretion system protein epsE - - ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N SYD1_k127_2235009_21 1131269.AQVV01000002_gene1187 2.327e-39 161.0 COG0737@1|root,COG0737@2|Bacteria 2|Bacteria F nucleotide catabolic process mnuA - - - - - - - - - - - 5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH SYD1_k127_2235009_26 315730.BcerKBAB4_2184 2.622e-23 102.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,1ZHUS@1386|Bacillus 91061|Bacilli L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hupA - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding SYD1_k127_2235009_5 1379698.RBG1_1C00001G0864 1.587e-119 425.0 COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria 2|Bacteria M involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - ko:K04744,ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - - LptC,OstA,OstA_C SYD1_k127_2235009_16 649638.Trad_1462 2.157e-68 250.0 COG0285@1|root,COG0285@2|Bacteria,1WI0C@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus H PFAM Mur ligase family, glutamate ligase domain - - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M SYD1_k127_2235009_9 1379698.RBG1_1C00001G1549 2.035e-102 347.0 COG0777@1|root,COG0777@2|Bacteria,2NP40@2323|unclassified Bacteria 2|Bacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601 Carboxyl_trans SYD1_k127_2235009_23 401526.TcarDRAFT_0379 3.143e-28 127.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4H4WN@909932|Negativicutes 909932|Negativicutes K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 SYD1_k127_2235009_28 292459.STH2925 5.156e-17 93.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia 186801|Clostridia O Universal bacterial protein YeaZ yeaZ - - ko:K14742 - - - - ko00000,ko03016 - - - Acetyltransf_1,Peptidase_M22 SYD1_k127_2235009_22 357808.RoseRS_4357 2.316e-28 120.0 COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi,375TA@32061|Chloroflexia 32061|Chloroflexia S Threonylcarbamoyl adenosine biosynthesis protein TsaE - - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE SYD1_k127_2235009_0 1519464.HY22_02335 4.462e-163 529.0 COG2204@1|root,COG2204@2|Bacteria,1FERH@1090|Chlorobi 1090|Chlorobi T PglZ domain - - - - - - - - - - - - PglZ,Response_reg SYD1_k127_2235009_15 1379698.RBG1_1C00001G1544 3.523e-80 283.0 COG4191@1|root,COG4191@2|Bacteria,2NPC5@2323|unclassified Bacteria 2|Bacteria T Integral membrane sensor signal transduction histidine kinase vicK - 2.1.1.80,2.7.13.3,3.1.1.61 ko:K07709,ko:K13924 ko02020,ko02030,map02020,map02030 M00499,M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA SYD1_k127_2235009_2 1379698.RBG1_1C00001G1543 2.584e-149 485.0 COG0172@1|root,COG0172@2|Bacteria,2NNRH@2323|unclassified Bacteria 2|Bacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b SYD1_k127_2235009_20 485916.Dtox_1251 1.948e-41 165.0 COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,2494Z@186801|Clostridia,260B2@186807|Peptococcaceae 186801|Clostridia H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC - 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS15760 Porphobil_deam,Porphobil_deamC SYD1_k127_2235009_8 861299.J421_5990 3.302e-106 357.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SYD1_k127_2235009_10 861299.J421_5991 1.554e-94 333.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SYD1_k127_2235009_14 886293.Sinac_1756 8.039e-85 291.0 COG1136@1|root,COG1136@2|Bacteria,2IWZ1@203682|Planctomycetes 203682|Planctomycetes V ABC-type antimicrobial peptide transport system, ATPase component - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SYD1_k127_2235009_17 1121013.P873_08195 1.822e-66 255.0 COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,1S0KD@1236|Gammaproteobacteria,1X3ST@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family acrE - - - - - - - - - - - HlyD_D23 SYD1_k127_2235009_7 1379698.RBG1_1C00001G1220 1.664e-115 394.0 COG0620@1|root,COG0620@2|Bacteria,2NPAE@2323|unclassified Bacteria 2|Bacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 Meth_synt_1,Meth_synt_2 SYD1_k127_2235009_19 309799.DICTH_1645 4.332e-43 170.0 COG0620@1|root,COG0620@2|Bacteria 2|Bacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 SYD1_k127_2235009_12 1157490.EL26_12510 1.24e-89 315.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,278RA@186823|Alicyclobacillaceae 91061|Bacilli EGP MFS_1 like family mdtG - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,MFS_1_like,Sugar_tr SYD1_k127_2235009_25 1379698.RBG1_1C00001G0517 3.718e-25 108.0 COG0489@1|root,COG0489@2|Bacteria,2NNX1@2323|unclassified Bacteria 2|Bacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA SYD1_k127_2235009_6 671143.DAMO_2385 7.168e-118 391.0 COG0489@1|root,COG0489@2|Bacteria,2NNX1@2323|unclassified Bacteria 2|Bacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA SYD1_k127_2235009_4 1379698.RBG1_1C00001G0521 2.068e-121 400.0 COG1071@1|root,COG1071@2|Bacteria,2NPBB@2323|unclassified Bacteria 2|Bacteria C Dehydrogenase E1 component bfmBA - 1.2.4.1,1.2.4.4 ko:K00161,ko:K00166,ko:K11381,ko:K21416 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C SYD1_k127_2235009_18 1051632.TPY_0992 3.805e-43 164.0 COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,24JIT@186801|Clostridia,3WDHI@538999|Clostridiales incertae sedis 186801|Clostridia I Thioesterase superfamily yciA - - - - - - - - - - - 4HBT SYD1_k127_2235009_3 1379698.RBG1_1C00001G0522 1.509e-127 424.0 COG0022@1|root,COG0022@2|Bacteria,2NNT2@2323|unclassified Bacteria 2|Bacteria C Transketolase, pyrimidine binding domain pdhB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944,GO:0140030,GO:0140032 1.2.4.1,1.2.4.4 ko:K00162,ko:K00167,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2496c,iSB619.SA_RS05355,iYO844.BSU14590,iYO844.BSU24040 Transket_pyr,Transketolase_C SYD1_k127_2235009_24 1379698.RBG1_1C00001G0523 8.627e-28 117.0 COG0508@1|root,COG0508@2|Bacteria,2NNZ8@2323|unclassified Bacteria 2|Bacteria C e3 binding domain sucB GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.168,2.3.1.61 ko:K00658,ko:K09699 ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032,M00036 R02570,R02571,R02662,R03174,R04097,R08549,R10998 RC00004,RC02727,RC02833,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2766,iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722 2-oxoacid_dh,Biotin_lipoyl,E3_binding SYD1_k127_2392832_16 204536.SULAZ_1549 6.889e-17 95.0 COG0066@1|root,COG0066@2|Bacteria,2G405@200783|Aquificae 200783|Aquificae E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C SYD1_k127_2392832_7 224324.aq_940 1.978e-69 258.0 COG0065@1|root,COG0065@2|Bacteria,2G3S3@200783|Aquificae 200783|Aquificae H Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase SYD1_k127_2392832_18 313603.FB2170_14823 0.0005972 53.0 2919D@1|root,2ZNWG@2|Bacteria,4NMU5@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - SYD1_k127_2392832_3 945713.IALB_0802 1.93e-121 404.0 COG0484@1|root,COG0484@2|Bacteria 2|Bacteria O heat shock protein binding - - - - - - - - - - - - - SYD1_k127_2392832_4 404589.Anae109_2645 3.318e-100 349.0 COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,4397N@68525|delta/epsilon subdivisions,2X4EI@28221|Deltaproteobacteria,2YYVA@29|Myxococcales 28221|Deltaproteobacteria C heat shock protein binding - - - - - - - - - - - - Cytochrome_C7 SYD1_k127_2392832_5 880073.Calab_3330 6.529e-95 330.0 COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,2NS2I@2323|unclassified Bacteria 2|Bacteria O Pyridine nucleotide-disulphide oxidoreductase trxB_2 - 1.18.1.2,1.19.1.1,1.8.1.9 ko:K00384,ko:K21567 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Fer4,Fer4_10,Pyr_redox_3 SYD1_k127_2392832_15 880073.Calab_3335 9.213e-30 130.0 COG0492@1|root,COG0492@2|Bacteria 2|Bacteria C ferredoxin-NADP+ reductase activity - - - - - - - - - - - - FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thioredoxin_3,cNMP_binding SYD1_k127_2392832_17 880073.Calab_2081 2.188e-16 94.0 COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria 2|Bacteria P LVIVD repeat - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - LVIVD SYD1_k127_2392832_6 1089550.ATTH01000001_gene449 5.281e-90 327.0 COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,4NTWX@976|Bacteroidetes 976|Bacteroidetes O Peptidase, S8 S53 family - - - - - - - - - - - - Peptidase_S8 SYD1_k127_2392832_8 292459.STH1727 3.023e-68 260.0 COG1051@1|root,COG1194@1|root,COG1051@2|Bacteria,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia 186801|Clostridia L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA SYD1_k127_2392832_11 391625.PPSIR1_11225 2.091e-47 187.0 COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria 1224|Proteobacteria H squalene-associated FAD-dependent desaturase hpnE - 1.17.8.1 ko:K21677 - - - - ko00000,ko01000 - - - Amino_oxidase SYD1_k127_2392832_9 330214.NIDE1520 9.399e-64 229.0 COG1562@1|root,COG1562@2|Bacteria,3J17J@40117|Nitrospirae 40117|Nitrospirae I Squalene/phytoene synthase - - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY SYD1_k127_2392832_10 1123368.AUIS01000001_gene2032 1.098e-52 212.0 COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,1S3EY@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Squalene/phytoene synthase - - - - - - - - - - - - SQS_PSY SYD1_k127_2392832_2 1379698.RBG1_1C00001G1660 1.326e-127 418.0 COG4867@1|root,COG4867@2|Bacteria,2NQZ8@2323|unclassified Bacteria 2|Bacteria S von Willebrand factor (vWF) type A domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA_2 SYD1_k127_2392832_0 518766.Rmar_2682 8.39e-183 585.0 COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,1FIU1@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H magnesium chelatase chlI - 6.6.1.1 ko:K03405 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R03877 RC01012 ko00000,ko00001,ko01000 - - - AAA_5,Sigma54_activat SYD1_k127_2392832_14 1304874.JAFY01000007_gene2179 7.321e-34 136.0 COG1522@1|root,COG1522@2|Bacteria,3TB3W@508458|Synergistetes 508458|Synergistetes K AsnC family - - - - - - - - - - - - AsnC_trans_reg,HTH_AsnC-type SYD1_k127_2392832_1 518766.Rmar_2194 2.439e-167 539.0 COG0160@1|root,COG0160@2|Bacteria,4NGPB@976|Bacteroidetes,1FITF@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family lat - 2.6.1.36 ko:K03918 ko01100,map01100 - R00457 RC00006,RC00062 ko00000,ko01000,ko01007 - - - Aminotran_3 SYD1_k127_2392832_12 926560.KE387023_gene3760 1.8e-40 161.0 COG2133@1|root,COG2133@2|Bacteria 2|Bacteria G pyrroloquinoline quinone binding - - - - - - - - - - - - CHRD,Malectin SYD1_k127_2392832_13 290397.Adeh_0133 1.665e-34 141.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WNXT@28221|Deltaproteobacteria,2YV4W@29|Myxococcales 28221|Deltaproteobacteria EGP of the major facilitator superfamily agmP - - ko:K08151 - M00668 - - ko00000,ko00002,ko01504,ko02000 2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75 - - MFS_1,MFS_1_like,Sugar_tr SYD1_k127_2406003_1 768066.HELO_2461 7.51e-39 152.0 COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,1RME6@1236|Gammaproteobacteria,1XIYC@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS SYD1_k127_2406003_0 1038859.AXAU01000016_gene6869 9.425e-166 536.0 COG0654@1|root,COG0654@2|Bacteria,1QWT3@1224|Proteobacteria,2U2GE@28211|Alphaproteobacteria,3JZXS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - - - - - - - - - - FAD_binding_3 SYD1_k127_2406003_2 1270196.JCKI01000006_gene2535 7.001e-08 59.0 COG3667@1|root,COG3667@2|Bacteria,4NICY@976|Bacteroidetes,1IWVR@117747|Sphingobacteriia 976|Bacteroidetes P copper resistance - - - - - - - - - - - - - SYD1_k127_2494387_1 497964.CfE428DRAFT_4035 5.057e-35 136.0 COG0019@1|root,COG0019@2|Bacteria 2|Bacteria E diaminopimelate decarboxylase activity lysA GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4,4.1.1.20 ko:K01586,ko:K12526 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00525,M00526,M00527 R00451,R00480 RC00002,RC00043,RC00299 ko00000,ko00001,ko00002,ko01000 - - iG2583_1286.G2583_3495 AA_kinase,Orn_Arg_deC_N,Orn_DAP_Arg_deC SYD1_k127_2494387_2 660470.Theba_0222 2.858e-11 77.0 COG1470@1|root,COG3291@1|root,COG1470@2|Bacteria,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 - R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 - GH33 - BNR_2,NPCBM,NPCBM_assoc,PEGA SYD1_k127_2494387_3 1089550.ATTH01000001_gene812 1.549e-07 64.0 COG1361@1|root,COG4412@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein - - - ko:K07004,ko:K09955,ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Laminin_G_3 SYD1_k127_2494387_4 459349.CLOAM1386 3.703e-05 55.0 COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria 2|Bacteria S peptidase activity, acting on L-amino acid peptides - - - - - - - - - - - - F5_F8_type_C,Fn3-like,PKD SYD1_k127_2494387_0 1173028.ANKO01000060_gene2889 9.434e-51 191.0 COG1404@1|root,COG1404@2|Bacteria,1G04D@1117|Cyanobacteria,1H779@1150|Oscillatoriales 1117|Cyanobacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - Calx-beta,PPC,Peptidase_S8,SdrD_B SYD1_k127_2550848_0 224308.BSU37890 2.171e-92 317.0 COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HDN8@91061|Bacilli,1ZQW8@1386|Bacillus 91061|Bacilli E Belongs to the DegT DnrJ EryC1 family spsC - 2.6.1.102 ko:K13010 ko00520,map00520 - R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 - - - DegT_DnrJ_EryC1 SYD1_k127_2550848_1 1227739.Hsw_2436 2.406e-38 161.0 COG0491@1|root,COG0491@2|Bacteria,4P569@976|Bacteroidetes,47W30@768503|Cytophagia 976|Bacteroidetes S Metallo-beta-lactamase superfamily - - - - - - - - - - - - - SYD1_k127_2675758_0 292459.STH167 1.251e-240 774.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia 186801|Clostridia L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran SYD1_k127_2675758_17 1123284.KB899046_gene2171 5.964e-15 82.0 COG2204@1|root,COG2204@2|Bacteria,1V6R9@1239|Firmicutes,4HIXH@91061|Bacilli 91061|Bacilli T receiver spo0F - - ko:K02490 ko02020,ko02024,map02020,map02024 M00485 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg SYD1_k127_2675758_3 1121918.ARWE01000001_gene445 1.611e-122 409.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales 28221|Deltaproteobacteria T Domains REC, sigma54 interaction, HTH8 - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_2675758_14 404380.Gbem_0282 1.457e-45 179.0 COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,42TFH@68525|delta/epsilon subdivisions,2WPEH@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase HAMP - - - - - - - - - - - - HAMP,HATPase_c,HisKA SYD1_k127_2675758_11 1379698.RBG1_1C00001G0456 2.403e-51 204.0 COG0760@1|root,COG0760@2|Bacteria,2NP7B@2323|unclassified Bacteria 2|Bacteria O Peptidylprolyl isomerase ppiD - 5.2.1.8 ko:K01802,ko:K03769,ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_2,SurA_N_3 SYD1_k127_2675758_18 290317.Cpha266_0577 7.102e-12 69.0 COG1826@1|root,COG1826@2|Bacteria,1FE6Y@1090|Chlorobi 1090|Chlorobi U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 SYD1_k127_2675758_21 1229172.JQFA01000002_gene3594 0.0005415 48.0 COG1316@1|root,COG1316@2|Bacteria,1G12M@1117|Cyanobacteria,1H6YC@1150|Oscillatoriales 1117|Cyanobacteria K Cell envelope-related transcriptional attenuator psr - - - - - - - - - - - LytR_C,LytR_cpsA_psr SYD1_k127_2675758_13 1121472.AQWN01000002_gene2110 9.207e-46 171.0 COG0537@1|root,COG0537@2|Bacteria,1V5CH@1239|Firmicutes,25CUE@186801|Clostridia,266WQ@186807|Peptococcaceae 186801|Clostridia FG Scavenger mRNA decapping enzyme C-term binding - - 2.7.7.53 ko:K19710 ko00230,map00230 - R00126,R01618 RC00002,RC02753,RC02795 ko00000,ko00001,ko01000 - - - HIT SYD1_k127_2675758_9 1458462.JNLK01000001_gene1548 1.591e-58 228.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,27JTA@186928|unclassified Lachnospiraceae 186801|Clostridia M 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase SYD1_k127_2675758_7 469383.Cwoe_2891 2.236e-69 257.0 COG0414@1|root,COG0414@2|Bacteria,2GJEQ@201174|Actinobacteria,4CPNC@84995|Rubrobacteria 84995|Rubrobacteria H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC - 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase SYD1_k127_2675758_5 1267534.KB906758_gene2264 9.374e-86 296.0 COG0413@1|root,COG0413@2|Bacteria,3Y3GX@57723|Acidobacteria,2JI6Y@204432|Acidobacteriia 204432|Acidobacteriia H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf SYD1_k127_2675758_8 880073.Calab_2860 1.59e-68 247.0 COG1428@1|root,COG1428@2|Bacteria,2NPEH@2323|unclassified Bacteria 2|Bacteria F Deoxynucleoside kinase dgk - 2.7.1.113 ko:K15518 ko00230,map00230 - R01967 RC00002,RC00017 ko00000,ko00001,ko01000 - - - HPPK,dNK SYD1_k127_2675758_15 1125863.JAFN01000001_gene2759 1.999e-39 158.0 COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,42TJ2@68525|delta/epsilon subdivisions,2WQ4P@28221|Deltaproteobacteria 28221|Deltaproteobacteria H PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK SYD1_k127_2675758_19 1183438.GKIL_0332 2.481e-09 65.0 COG1539@1|root,COG1539@2|Bacteria,1G6RT@1117|Cyanobacteria 1117|Cyanobacteria H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB SYD1_k127_2675758_4 1304872.JAGC01000009_gene1155 1.182e-116 388.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2WKPT@28221|Deltaproteobacteria,2M8SR@213115|Desulfovibrionales 28221|Deltaproteobacteria E Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate dapL - 2.6.1.83 ko:K10206 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 M00527 R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 SYD1_k127_2675758_10 1379698.RBG1_1C00001G0434 1.571e-53 202.0 COG0812@1|root,COG0812@2|Bacteria,2NPHQ@2323|unclassified Bacteria 2|Bacteria M Cell wall formation murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C SYD1_k127_2675758_12 1210884.HG799468_gene13696 7.651e-47 177.0 COG1321@1|root,COG1321@2|Bacteria,2IYW3@203682|Planctomycetes 203682|Planctomycetes K iron dependent repressor - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA SYD1_k127_2675758_2 1379698.RBG1_1C00001G1189 5.614e-182 590.0 COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,2NP5W@2323|unclassified Bacteria 2|Bacteria U H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp,Usp SYD1_k127_2675758_16 643867.Ftrac_2185 1.286e-18 86.0 COG1983@1|root,COG1983@2|Bacteria,4NWKE@976|Bacteroidetes,47SK6@768503|Cytophagia 976|Bacteroidetes KT PspC domain pspC - - - - - - - - - - - PspC SYD1_k127_2675758_1 497964.CfE428DRAFT_5191 6.902e-233 732.0 COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia 74201|Verrucomicrobia O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 SYD1_k127_2675758_6 717605.Theco_3678 1.283e-81 283.0 COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,26RR9@186822|Paenibacillaceae 91061|Bacilli H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase SYD1_k127_2675758_22 436229.JOEH01000034_gene3549 0.0007259 45.0 COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,2NGJ6@228398|Streptacidiphilus 201174|Actinobacteria H Biotin protein ligase C terminal domain birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB SYD1_k127_2858020_3 6087.XP_002166121.1 6.638e-12 69.0 KOG2177@1|root,KOG2177@2759|Eukaryota,38EA3@33154|Opisthokonta,3BFJH@33208|Metazoa 33208|Metazoa O zinc ion binding - - - ko:K11997 - - - - ko00000,ko04121 - - - Filamin,NHL,zf-B_box SYD1_k127_2858020_2 765420.OSCT_0597 4.122e-25 117.0 COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi,3757B@32061|Chloroflexia 32061|Chloroflexia O PFAM NHL repeat containing protein - - - - - - - - - - - - NHL,PMT_2 SYD1_k127_2858020_1 324602.Caur_3622 3.396e-49 194.0 COG2520@1|root,COG2520@2|Bacteria 2|Bacteria J tRNA (guanine(37)-N(1))-methyltransferase activity XK27_03530 - - - - - - - - - - - Methyltransf_21,rRNA_methylase SYD1_k127_2858020_0 1128421.JAGA01000002_gene798 6.259e-91 318.0 COG1287@1|root,COG1287@2|Bacteria 2|Bacteria S oligosaccharyl transferase activity - - - - - - - - - - - - PMT_2 SYD1_k127_2934756_1 1379698.RBG1_1C00001G1225 5.641e-166 532.0 COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria 2|Bacteria J Ribosomal protein S1 rpsA GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 ko:K02945,ko:K03527,ko:K12132 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011 - - - S1 SYD1_k127_2934756_11 443143.GM18_3291 4.548e-82 287.0 COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,42MJK@68525|delta/epsilon subdivisions,2WJ8V@28221|Deltaproteobacteria,43SW9@69541|Desulfuromonadales 28221|Deltaproteobacteria F Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 - - - LYTB,UbiA SYD1_k127_2934756_19 555088.DealDRAFT_0660 1.551e-28 134.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,25B02@186801|Clostridia,42K0K@68298|Syntrophomonadaceae 186801|Clostridia I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase SYD1_k127_2934756_15 1329516.JPST01000028_gene3345 3.151e-43 182.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,27BSM@186824|Thermoactinomycetaceae 91061|Bacilli F Cytidylate kinase-like family cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin SYD1_k127_2934756_7 477974.Daud_1181 1.238e-102 349.0 COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,2603K@186807|Peptococcaceae 186801|Clostridia E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase SYD1_k127_2934756_8 555088.DealDRAFT_0299 1.87e-98 333.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,42JMR@68298|Syntrophomonadaceae 186801|Clostridia E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 SYD1_k127_2934756_14 429009.Adeg_1292 5.093e-46 176.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,42G4B@68295|Thermoanaerobacterales 186801|Clostridia J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 SYD1_k127_2934756_17 671143.DAMO_1200 2.19e-38 161.0 COG1386@1|root,COG1386@2|Bacteria,2NPPM@2323|unclassified Bacteria 2|Bacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB SYD1_k127_2934756_16 411489.CLOL250_00245 5.364e-41 172.0 COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,36EKU@31979|Clostridiaceae 186801|Clostridia D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA SYD1_k127_2934756_6 880073.Calab_3591 3.149e-118 389.0 COG0180@1|root,COG0180@2|Bacteria,2NNQX@2323|unclassified Bacteria 2|Bacteria J tRNA synthetases class I (W and Y) trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b SYD1_k127_2934756_18 102232.GLO73106DRAFT_00012510 5.038e-29 132.0 COG0612@1|root,COG0612@2|Bacteria,1G0D3@1117|Cyanobacteria 1117|Cyanobacteria S Peptidase family M16 - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C SYD1_k127_2934756_9 1121920.AUAU01000023_gene2396 1.455e-86 306.0 COG0773@1|root,COG1376@1|root,COG0773@2|Bacteria,COG1376@2|Bacteria,3Y304@57723|Acidobacteria 57723|Acidobacteria M Belongs to the MurCDEF family - - - - - - - - - - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M,YkuD SYD1_k127_2934756_0 1382306.JNIM01000001_gene1354 5.524e-191 609.0 COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi 200795|Chloroflexi C Belongs to the aldehyde dehydrogenase family - - 1.2.1.88 ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 - R00245,R00707,R00708,R04444,R04445,R05051 RC00080,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000 - - - Aldedh SYD1_k127_2934756_24 459349.CLOAM0061 2.264e-12 80.0 COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria 2|Bacteria NU bacterial-type flagellum-dependent cell motility wprA - 3.1.3.6,3.1.4.16,3.2.1.99 ko:K01119,ko:K06113,ko:K12685,ko:K20276 ko00230,ko00240,ko02024,map00230,map00240,map02024 - R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000,ko02000,ko02044 1.B.12.5.1,1.B.12.5.3 GH43 - Mucin_bdg,Peptidase_M60,Peptidase_S8,SLH SYD1_k127_2934756_21 195250.CM001776_gene1647 4.083e-20 106.0 COG1572@1|root,COG1864@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1GED2@1117|Cyanobacteria,1H2ZS@1129|Synechococcus 1117|Cyanobacteria G Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - PKD SYD1_k127_2934756_2 1123368.AUIS01000024_gene950 3.85e-146 489.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1SYDD@1236|Gammaproteobacteria,2NCJF@225057|Acidithiobacillales 225057|Acidithiobacillales V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 SYD1_k127_2934756_3 1123368.AUIS01000024_gene949 1.22e-144 471.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,2NBU9@225057|Acidithiobacillales 225057|Acidithiobacillales V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 SYD1_k127_2934756_4 1123368.AUIS01000024_gene948 4.094e-127 429.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,2NCCI@225057|Acidithiobacillales 225057|Acidithiobacillales V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 SYD1_k127_2934756_5 1123368.AUIS01000024_gene947 6.294e-123 419.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,2NDPN@225057|Acidithiobacillales 225057|Acidithiobacillales V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SYD1_k127_2934756_10 1123368.AUIS01000024_gene946 1.433e-84 309.0 COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RS3I@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Secretion protein yhiI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 SYD1_k127_2934756_23 1121405.dsmv_3543 7.162e-17 94.0 COG1538@1|root,COG1538@2|Bacteria,1PDZP@1224|Proteobacteria,42MJH@68525|delta/epsilon subdivisions,2WJ2X@28221|Deltaproteobacteria,2MNJH@213118|Desulfobacterales 28221|Deltaproteobacteria MU Outer membrane efflux protein - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP SYD1_k127_2934756_13 880072.Desac_1709 1.01e-46 176.0 COG1309@1|root,COG1309@2|Bacteria,1ND26@1224|Proteobacteria,43EW9@68525|delta/epsilon subdivisions,2X29Y@28221|Deltaproteobacteria,2MSD6@213462|Syntrophobacterales 28221|Deltaproteobacteria K YsiA-like protein, C-terminal region - - - - - - - - - - - - TetR_C_4 SYD1_k127_2934756_12 1123376.AUIU01000012_gene1496 1.815e-56 205.0 COG0681@1|root,COG0681@2|Bacteria,3J0IP@40117|Nitrospirae 40117|Nitrospirae U Signal peptidase, peptidase S26 lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 SYD1_k127_2934756_20 1379698.RBG1_1C00001G0193 3.573e-28 121.0 COG0797@1|root,COG0797@2|Bacteria,2NPV9@2323|unclassified Bacteria 2|Bacteria M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR SYD1_k127_3354396_35 880073.Calab_0615 2.484e-50 196.0 COG0571@1|root,COG0571@2|Bacteria,2NPCJ@2323|unclassified Bacteria 2|Bacteria J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm SYD1_k127_3354396_5 1121468.AUBR01000030_gene1226 6.074e-168 539.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,42FCV@68295|Thermoanaerobacterales 186801|Clostridia I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt SYD1_k127_3354396_52 224324.aq_1717a 2.071e-25 108.0 COG0236@1|root,COG0236@2|Bacteria,2G491@200783|Aquificae 200783|Aquificae IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding SYD1_k127_3354396_29 562970.Btus_1443 9.328e-71 261.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,279C6@186823|Alicyclobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU15910 adh_short_C2 SYD1_k127_3354396_26 997346.HMPREF9374_0897 6.87e-85 306.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,27BCT@186824|Thermoactinomycetaceae 91061|Bacilli I Acyl transferase domain fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 SYD1_k127_3354396_12 1121472.AQWN01000002_gene2330 4.916e-115 381.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,260BR@186807|Peptococcaceae 186801|Clostridia I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C SYD1_k127_3354396_21 671143.DAMO_1438 6.376e-91 310.0 COG0416@1|root,COG0416@2|Bacteria,2NP1H@2323|unclassified Bacteria 2|Bacteria I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 ko:K03621,ko:K21576,ko:K21577 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis SYD1_k127_3354396_57 1379698.RBG1_1C00001G1829 3.779e-20 92.0 COG0333@1|root,COG0333@2|Bacteria,2NQ1M@2323|unclassified Bacteria 2|Bacteria J Ribosomal L32p protein family rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p SYD1_k127_3354396_58 292459.STH1442 7.873e-20 96.0 COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia 186801|Clostridia S acr, cog1399 - - - ko:K07040 - - - - ko00000 - - - DUF177 SYD1_k127_3354396_43 272556.CF65_00722 2.153e-41 156.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,1Y8PF@135625|Pasteurellales 135625|Pasteurellales F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK SYD1_k127_3354396_13 1521187.JPIM01000102_gene3720 1.253e-111 387.0 COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi,375DE@32061|Chloroflexia 32061|Chloroflexia C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA SYD1_k127_3354396_14 1236504.HMPREF2132_12970 2.251e-110 371.0 COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,2FNFG@200643|Bacteroidia 976|Bacteroidetes C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA SYD1_k127_3354396_2 644966.Tmar_1089 4.686e-207 657.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia 186801|Clostridia C Belongs to the aldehyde dehydrogenase family - - - ko:K22187 ko00040,map00040 - R11768 RC00080 ko00000,ko00001,ko01000 - - - Aldedh SYD1_k127_3354396_62 880073.Calab_0923 2.978e-14 85.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family ebh - - - - - - - - - - - DUF1611,Inhibitor_I9,Peptidase_S8,SLH SYD1_k127_3354396_73 1346791.M529_20550 8.55e-06 59.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TUXY@28211|Alphaproteobacteria,2K16Q@204457|Sphingomonadales 204457|Sphingomonadales EU peptidase S9 - - - - - - - - - - - - PD40,Peptidase_S9 SYD1_k127_3354396_63 1191523.MROS_2238 1.207e-13 84.0 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - 3.2.1.45 ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 - R01498 RC00059,RC00451 ko00000,ko00001,ko01000 - GH30 - CBM_6,fn3 SYD1_k127_3354396_69 1268303.RHODMAR_4992 1.244e-07 57.0 COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4FXQJ@85025|Nocardiaceae 201174|Actinobacteria L IstB-like ATP binding protein - - - - - - - - - - - - IstB_IS21 SYD1_k127_3354396_75 880073.Calab_2400 0.0004407 53.0 2E2T1@1|root,32XVB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_3354396_67 1121930.AQXG01000023_gene1641 2.209e-09 70.0 COG3209@1|root,COG3209@2|Bacteria,4P5ZD@976|Bacteroidetes 976|Bacteroidetes M COG3209 Rhs family protein - - - - - - - - - - - - - SYD1_k127_3354396_61 1191523.MROS_2238 4.605e-15 91.0 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - 3.2.1.45 ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 - R01498 RC00059,RC00451 ko00000,ko00001,ko01000 - GH30 - CBM_6,fn3 SYD1_k127_3354396_6 498761.HM1_2458 9.635e-153 507.0 COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,248RS@186801|Clostridia 186801|Clostridia J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f SYD1_k127_3354396_9 639282.DEFDS_0639 5.847e-129 432.0 COG0752@1|root,COG0752@2|Bacteria,2GEZ4@200930|Deferribacteres 200930|Deferribacteres J Glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e SYD1_k127_3354396_54 525264.HMPREF0305_12126 2.38e-23 115.0 COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,22K9A@1653|Corynebacteriaceae 201174|Actinobacteria L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N SYD1_k127_3354396_42 1238182.C882_3846 1.532e-42 169.0 COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2TZPK@28211|Alphaproteobacteria,2JRPM@204441|Rhodospirillales 204441|Rhodospirillales S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 SYD1_k127_3354396_59 864563.HMPREF9166_2124 2.105e-17 89.0 COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4H4HY@909932|Negativicutes 909932|Negativicutes S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 SYD1_k127_3354396_18 880073.Calab_2813 1.848e-97 347.0 COG1480@1|root,COG1480@2|Bacteria,2NP1K@2323|unclassified Bacteria 2|Bacteria S 7TM receptor with intracellular HD hydrolase yqfF - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD SYD1_k127_3354396_19 935948.KE386493_gene2414 1.35e-94 334.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,42EZD@68295|Thermoanaerobacterales 186801|Clostridia T PFAM PhoH family protein phoH - - ko:K06217 - - - - ko00000 - - - PhoH SYD1_k127_3354396_65 1380394.JADL01000014_gene216 7.622e-11 71.0 COG1652@1|root,COG1652@2|Bacteria,1MWMR@1224|Proteobacteria,2U7UH@28211|Alphaproteobacteria,2JXDP@204441|Rhodospirillales 204441|Rhodospirillales S LysM domain - - - - - - - - - - - - LysM SYD1_k127_3354396_3 665571.STHERM_c01570 8.656e-185 615.0 COG0173@1|root,COG0173@2|Bacteria,2J5KG@203691|Spirochaetes 203691|Spirochaetes J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon SYD1_k127_3354396_10 1144275.COCOR_04279 1.181e-118 404.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria,2YTVY@29|Myxococcales 28221|Deltaproteobacteria J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His SYD1_k127_3354396_70 869210.Marky_0410 1.789e-07 63.0 COG5652@1|root,COG5652@2|Bacteria,1WKND@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM VanZ like family - - - - - - - - - - - - VanZ SYD1_k127_3354396_4 880073.Calab_2940 6.147e-173 552.0 COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria 2|Bacteria E Cys/Met metabolism PLP-dependent enzyme - - 4.4.1.11,4.4.1.8 ko:K01760,ko:K01761 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00654,R00782,R01286,R02408,R04770,R04941 RC00056,RC00069,RC00196,RC00348,RC00382,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP SYD1_k127_3354396_72 502025.Hoch_5623 5.857e-06 59.0 COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1R8QH@1224|Proteobacteria,42T02@68525|delta/epsilon subdivisions,2WPNU@28221|Deltaproteobacteria,2YUP3@29|Myxococcales 28221|Deltaproteobacteria MU WD40-like Beta Propeller Repeat - - - - - - - - - - - - Bac_surface_Ag,PD40 SYD1_k127_3354396_50 59374.Fisuc_1572 9.402e-31 128.0 COG1762@1|root,COG1762@2|Bacteria 2|Bacteria G phosphoenolpyruvate-dependent sugar phosphotransferase system ptsN3 - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 SYD1_k127_3354396_0 370438.PTH_2122 0.0 1047.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,2602D@186807|Peptococcaceae 186801|Clostridia O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N SYD1_k127_3354396_53 1122925.KB895376_gene457 3.175e-25 118.0 COG0500@1|root,COG2227@1|root,COG2226@2|Bacteria,COG2227@2|Bacteria,1U21D@1239|Firmicutes,4IBI9@91061|Bacilli,270JI@186822|Paenibacillaceae 91061|Bacilli Q Tellurite resistance protein TehB - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 SYD1_k127_3354396_55 1125863.JAFN01000001_gene2298 3.541e-23 113.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42T19@68525|delta/epsilon subdivisions,2WQ0M@28221|Deltaproteobacteria 28221|Deltaproteobacteria D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - - - - - - - - - - TPR_16,TPR_6 SYD1_k127_3354396_45 671143.DAMO_3057 3.371e-39 152.0 COG2885@1|root,COG2885@2|Bacteria,2NPMV@2323|unclassified Bacteria 2|Bacteria M OmpA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA SYD1_k127_3354396_25 1379698.RBG1_1C00001G0500 1.621e-85 304.0 COG0823@1|root,COG0823@2|Bacteria,2NNZC@2323|unclassified Bacteria 2|Bacteria U TolB amino-terminal domain tolB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N SYD1_k127_3354396_60 1379698.RBG1_1C00001G0499 1.603e-15 87.0 COG0810@1|root,COG0810@2|Bacteria,2NQ3G@2323|unclassified Bacteria 2|Bacteria M TonB C terminal - - - ko:K03646,ko:K03832 - - - - ko00000,ko02000 2.C.1.1,2.C.1.2 - - CarbopepD_reg_2,TonB_2,TonB_C SYD1_k127_3354396_8 1121468.AUBR01000048_gene1658 2.155e-134 455.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,42FQX@68295|Thermoanaerobacterales 186801|Clostridia E Belongs to the aspartokinase family lysC - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 SYD1_k127_3354396_36 868595.Desca_2000 2.839e-49 199.0 COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,26127@186807|Peptococcaceae 186801|Clostridia E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB - 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS03525 GHMP_kinases_C,GHMP_kinases_N SYD1_k127_3354396_11 706587.Desti_1694 5.254e-116 403.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Threonine synthase - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP SYD1_k127_3354396_20 243233.MCA0597 9.913e-92 321.0 COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,1XEDH@135618|Methylococcales 135618|Methylococcales E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 SYD1_k127_3354396_34 1410619.SRDD_03600 7.36e-53 192.0 COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,1RNPQ@1236|Gammaproteobacteria,3ZZSQ@613|Serratia 1236|Gammaproteobacteria F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran SYD1_k127_3354396_28 880073.Calab_0823 3.524e-74 254.0 COG0572@1|root,COG0572@2|Bacteria,2NPKT@2323|unclassified Bacteria 2|Bacteria F Phosphoribulokinase / Uridine kinase family udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 ko:K00855,ko:K00876 ko00240,ko00710,ko00983,ko01100,ko01120,ko01200,map00240,map00710,map00983,map01100,map01120,map01200 M00165,M00166 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01523,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSBO_1134.SBO_0893 PRK SYD1_k127_3354396_64 290318.Cvib_1448 9.281e-13 82.0 COG1079@1|root,COG1079@2|Bacteria,1FDHG@1090|Chlorobi 1090|Chlorobi P Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 SYD1_k127_3354396_37 717605.Theco_1937 5.473e-49 196.0 COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,26TPG@186822|Paenibacillaceae 91061|Bacilli F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1,2.4.2.28 ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 M00034 R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 SYD1_k127_3354396_31 483219.LILAB_31320 2.751e-56 222.0 COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales 28221|Deltaproteobacteria M Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - HEAT_2,Pro_isomerase SYD1_k127_3354396_56 765420.OSCT_0740 1.205e-22 110.0 COG0859@1|root,COG0859@2|Bacteria,2G6JB@200795|Chloroflexi 200795|Chloroflexi M PFAM glycosyl transferase family 9 - - - ko:K02843,ko:K02849 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 SYD1_k127_3354396_71 1125863.JAFN01000001_gene1367 2.055e-07 58.0 COG5660@1|root,COG5660@2|Bacteria 2|Bacteria S Putative zinc-finger - - - - - - - - - - - - zf-HC2 SYD1_k127_3354396_40 278963.ATWD01000001_gene4342 1.84e-45 172.0 COG1595@1|root,COG1595@2|Bacteria,3Y3BS@57723|Acidobacteria,2JIDF@204432|Acidobacteriia 204432|Acidobacteriia K RNA polymerase sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SYD1_k127_3354396_24 1125863.JAFN01000001_gene1060 3.751e-88 314.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFA@28221|Deltaproteobacteria 28221|Deltaproteobacteria T response regulator - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_3354396_30 1123368.AUIS01000026_gene1459 6.536e-66 234.0 COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,1RNWU@1236|Gammaproteobacteria,2NCT5@225057|Acidithiobacillales 225057|Acidithiobacillales O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR SYD1_k127_3354396_27 292415.Tbd_0208 1.546e-77 277.0 COG4767@1|root,COG4767@2|Bacteria,1N67E@1224|Proteobacteria,2WGZ8@28216|Betaproteobacteria 28216|Betaproteobacteria V VanZ like family - - - - - - - - - - - - VanZ SYD1_k127_3354396_1 880073.Calab_2438 9.128e-296 919.0 COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria 2|Bacteria O Heat shock 70 kDa protein dnaK GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 SYD1_k127_3354396_48 1499967.BAYZ01000095_gene4149 5.227e-34 137.0 COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria 2|Bacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 SYD1_k127_3354396_23 563192.HMPREF0179_00703 2.72e-88 309.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales 28221|Deltaproteobacteria T Two component, sigma54 specific, transcriptional regulator, Fis family - - - ko:K02481,ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_3354396_41 460265.Mnod_3288 2.114e-44 180.0 COG1216@1|root,COG1216@2|Bacteria,1R06Z@1224|Proteobacteria,2VGUR@28211|Alphaproteobacteria,1JUBY@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Glycosyl transferase, family 2 - - - - - - - - - - - - GT87 SYD1_k127_3354396_7 1242864.D187_006544 5.449e-148 485.0 COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,42MS6@68525|delta/epsilon subdivisions,2WIYE@28221|Deltaproteobacteria,2YUMA@29|Myxococcales 28221|Deltaproteobacteria M Glycosyl transferase family 21 - - - - - - - - - - - - Glyco_tranf_2_3 SYD1_k127_3354396_22 1303518.CCALI_02392 2.096e-90 328.0 COG3387@1|root,COG3387@2|Bacteria 2|Bacteria G glucan 1,4-alpha-glucosidase activity - - - - - - - - - - - - Glyco_hydro_15 SYD1_k127_3354396_74 1121007.AUML01000016_gene193 0.000203 54.0 COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1HXXP@117743|Flavobacteriia,2YIDC@290174|Aquimarina 976|Bacteroidetes I membrane - - - - - - - - - - - - - SYD1_k127_3354396_68 313612.L8106_17377 6.403e-09 64.0 COG0642@1|root,COG2205@2|Bacteria,1FZZD@1117|Cyanobacteria,1H9NJ@1150|Oscillatoriales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like - - - - - - - - - - - - GAF,GAF_3,HATPase_c,HisKA SYD1_k127_3354396_49 696747.NIES39_M00460 1.134e-33 135.0 COG0784@1|root,COG0784@2|Bacteria,1G5VY@1117|Cyanobacteria,1HB3F@1150|Oscillatoriales 1117|Cyanobacteria T Response regulator receiver domain divK - - - - - - - - - - - Response_reg SYD1_k127_3354396_51 1122947.FR7_4390 2.129e-27 121.0 COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,1TS3B@1239|Firmicutes,4H88H@909932|Negativicutes 909932|Negativicutes T PFAM protein phosphatase 2C domain protein, response regulator receiver - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - Response_reg,SpoIIE SYD1_k127_3354396_38 459349.CLOAM1198 8.849e-48 179.0 2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SYD1_k127_3354396_33 1379698.RBG1_1C00001G0113 3.121e-53 200.0 28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SYD1_k127_3354396_46 1379698.RBG1_1C00001G0118 4.421e-35 149.0 29ZH8@1|root,30MGZ@2|Bacteria,2NQ83@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_3354396_17 1379698.RBG1_1C00001G0119 7.797e-101 341.0 28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SYD1_k127_3354396_15 518766.Rmar_0508 9.149e-107 368.0 COG2203@1|root,COG2204@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1FJ5I@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes T Bacterial regulatory protein, Fis family - - - ko:K02584 ko02020,map02020 - - - ko00000,ko00001,ko03000 - - - Sigma54_activat SYD1_k127_3354396_47 357808.RoseRS_4524 1.449e-34 153.0 COG0472@1|root,COG0472@2|Bacteria,2G7WQ@200795|Chloroflexi,375BA@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase family 4 - - 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 SYD1_k127_3354396_44 1112214.AHIS01000084_gene3706 3.961e-41 176.0 COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2TR88@28211|Alphaproteobacteria,2K0WY@204457|Sphingomonadales 204457|Sphingomonadales M Glycosyl transferase - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4 SYD1_k127_3354396_16 1232410.KI421412_gene272 3.554e-102 356.0 COG0438@1|root,COG0438@2|Bacteria,1MWYH@1224|Proteobacteria,42Q22@68525|delta/epsilon subdivisions,2WK61@28221|Deltaproteobacteria,43TI1@69541|Desulfuromonadales 28221|Deltaproteobacteria M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 SYD1_k127_3354396_39 1232410.KI421412_gene273 5.297e-47 191.0 COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,42VRI@68525|delta/epsilon subdivisions,2WRUV@28221|Deltaproteobacteria,43VFC@69541|Desulfuromonadales 28221|Deltaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 SYD1_k127_3354396_32 596152.DesU5LDRAFT_0048 7.673e-55 205.0 COG1216@1|root,COG2327@1|root,COG1216@2|Bacteria,COG2327@2|Bacteria,1RHX9@1224|Proteobacteria 1224|Proteobacteria S Polysaccharide pyruvyl transferase - - - - - - - - - - - - PS_pyruv_trans SYD1_k127_3354396_66 1541065.JRFE01000007_gene5101 8.907e-10 63.0 COG2242@1|root,COG2242@2|Bacteria,1GA6X@1117|Cyanobacteria 1117|Cyanobacteria H Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 SYD1_k127_3386748_17 1379698.RBG1_1C00001G0523 7.292e-93 313.0 COG0508@1|root,COG0508@2|Bacteria,2NNZ8@2323|unclassified Bacteria 2|Bacteria C e3 binding domain sucB GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.168,2.3.1.61 ko:K00658,ko:K09699 ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032,M00036 R02570,R02571,R02662,R03174,R04097,R08549,R10998 RC00004,RC02727,RC02833,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2766,iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722 2-oxoacid_dh,Biotin_lipoyl,E3_binding SYD1_k127_3386748_32 1123386.AUIW01000008_gene1877 2.778e-57 207.0 COG0321@1|root,COG0321@2|Bacteria,1WIJ7@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB SYD1_k127_3386748_8 1382359.JIAL01000001_gene773 3.344e-155 504.0 COG1027@1|root,COG1027@2|Bacteria,3Y3XS@57723|Acidobacteria,2JHYF@204432|Acidobacteriia 204432|Acidobacteriia E Fumarase C C-terminus - - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 SYD1_k127_3386748_34 304371.MCP_2646 9.811e-54 205.0 COG0477@1|root,arCOG00132@2157|Archaea,2XYHV@28890|Euryarchaeota 28890|Euryarchaeota G Major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr SYD1_k127_3386748_19 314230.DSM3645_22234 3.436e-86 301.0 COG0639@1|root,COG0639@2|Bacteria,2J22W@203682|Planctomycetes 203682|Planctomycetes T Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 SYD1_k127_3386748_47 1121403.AUCV01000045_gene1145 1.205e-30 128.0 2AVTU@1|root,31MME@2|Bacteria,1NQ7V@1224|Proteobacteria,42XCN@68525|delta/epsilon subdivisions,2WTFJ@28221|Deltaproteobacteria,2MNKH@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - SYD1_k127_3386748_21 1131269.AQVV01000020_gene2210 3.363e-83 288.0 COG0535@1|root,COG0535@2|Bacteria 2|Bacteria I radical SAM domain protein - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM SYD1_k127_3386748_61 457570.Nther_0583 3.566e-06 55.0 COG1633@1|root,COG1633@2|Bacteria,1V4P6@1239|Firmicutes,24IYH@186801|Clostridia 186801|Clostridia S Rubrerythrin - - - - - - - - - - - - Rubrerythrin SYD1_k127_3386748_28 1236689.MMALV_10860 2.013e-66 241.0 COG0492@1|root,arCOG01296@2157|Archaea,2XTJW@28890|Euryarchaeota,3F2RU@33867|unclassified Euryarchaeota 28890|Euryarchaeota O Pyridine nucleotide-disulphide oxidoreductase trxB - 1.18.1.2,1.19.1.1,1.8.1.9 ko:K00384,ko:K03387,ko:K21567 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Glutaredoxin,Pyr_redox_2 SYD1_k127_3386748_22 215803.DB30_5318 2.213e-81 303.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,42RID@68525|delta/epsilon subdivisions,2WN9N@28221|Deltaproteobacteria,2YUME@29|Myxococcales 28221|Deltaproteobacteria S Zn-dependent proteases and their inactivated homologs pmbA - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD SYD1_k127_3386748_14 378806.STAUR_3241 9.507e-114 386.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,42QCV@68525|delta/epsilon subdivisions,2WJP8@28221|Deltaproteobacteria,2YUBA@29|Myxococcales 28221|Deltaproteobacteria S Putative modulator of DNA gyrase tldD - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD SYD1_k127_3386748_55 309801.trd_A0913 1.13e-18 95.0 COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi,27YIV@189775|Thermomicrobia 189775|Thermomicrobia S Uncharacterized conserved protein (DUF2203) - - - - - - - - - - - - DUF2203 SYD1_k127_3386748_7 273068.TTE2516 2.056e-165 540.0 COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,42FCI@68295|Thermoanaerobacterales 186801|Clostridia L DNA polymerase polX - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP SYD1_k127_3386748_36 1133850.SHJG_1726 1.733e-48 196.0 COG3590@1|root,COG3590@2|Bacteria,2GW6H@201174|Actinobacteria 201174|Actinobacteria O peptidase - - - - - - - - - - - - - SYD1_k127_3386748_43 1163408.UU9_05999 1.598e-39 162.0 COG2010@1|root,COG2010@2|Bacteria,1MW1W@1224|Proteobacteria,1S1DG@1236|Gammaproteobacteria,1X6MQ@135614|Xanthomonadales 135614|Xanthomonadales C SnoaL-like domain - - - - - - - - - - - - Cytochrome_CBB3,DUF4440 SYD1_k127_3386748_23 204669.Acid345_3437 1.308e-70 248.0 COG2220@1|root,COG2220@2|Bacteria,3Y4RK@57723|Acidobacteria,2JM7M@204432|Acidobacteriia 204432|Acidobacteriia S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_3 SYD1_k127_3386748_62 665571.STHERM_c08610 9.364e-06 59.0 COG0526@1|root,COG0526@2|Bacteria,2J8ET@203691|Spirochaetes 203691|Spirochaetes CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA SYD1_k127_3386748_20 926550.CLDAP_25410 3.686e-86 294.0 COG0177@1|root,COG0177@2|Bacteria,2G6A1@200795|Chloroflexi 200795|Chloroflexi L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD SYD1_k127_3386748_46 330214.NIDE0518 3.075e-31 131.0 COG2802@1|root,COG2802@2|Bacteria,3J13Q@40117|Nitrospirae 40117|Nitrospirae S ATP-dependent protease La (LON) substrate-binding domain - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg SYD1_k127_3386748_16 396588.Tgr7_0891 9.317e-98 332.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1WWZ4@135613|Chromatiales 135613|Chromatiales C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG - 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 SYD1_k127_3386748_26 1267533.KB906733_gene3420 1.318e-69 245.0 COG0412@1|root,COG0412@2|Bacteria,3Y4P0@57723|Acidobacteria,2JJCI@204432|Acidobacteriia 204432|Acidobacteriia Q Dienelactone hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH SYD1_k127_3386748_60 1463921.JODF01000013_gene3794 1.343e-07 64.0 COG1032@1|root,COG1032@2|Bacteria,2GZU1@201174|Actinobacteria 201174|Actinobacteria C radical SAM domain protein - - - - - - - - - - - - - SYD1_k127_3386748_48 582515.KR51_00013230 1.089e-29 126.0 COG1194@1|root,COG1194@2|Bacteria,1G7MC@1117|Cyanobacteria 1117|Cyanobacteria L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 SYD1_k127_3386748_49 945713.IALB_1464 1.285e-28 129.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity luxD - 3.2.1.4,4.2.99.18 ko:K01179,ko:K06889,ko:K10773,ko:K15853 ko00500,ko01100,ko02020,ko02024,ko03410,map00500,map01100,map02020,map02024,map03410 - R06200,R11307,R11308 - ko00000,ko00001,ko01000,ko03400 - GH5,GH9 - Abhydrolase_1,Acyl_transf_2,DLH,Hydrolase_4,Peptidase_S9 SYD1_k127_3386748_39 290397.Adeh_1456 4.614e-44 171.0 COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2X5P3@28221|Deltaproteobacteria,2Z36M@29|Myxococcales 28221|Deltaproteobacteria S YceI-like domain - - - - - - - - - - - - YceI SYD1_k127_3386748_12 671143.DAMO_1612 9.481e-123 408.0 COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria 2|Bacteria O Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 ko:K00384,ko:K03671,ko:K22345 ko00030,ko00450,ko04621,ko05418,map00030,map00450,map04621,map05418 - R01544,R02016,R03596,R09372 RC00013,RC00544,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 - - iNJ661.Rv3913,iPC815.YPO1374 Pyr_redox_2 SYD1_k127_3386748_5 204669.Acid345_3065 4.355e-181 610.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia 204432|Acidobacteriia C Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S - - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO SYD1_k127_3386748_31 269799.Gmet_2358 1.21e-57 210.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,43SYM@69541|Desulfuromonadales 28221|Deltaproteobacteria V Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner lolD - - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran SYD1_k127_3386748_15 234267.Acid_7100 1.705e-102 365.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity salY - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SYD1_k127_3386748_27 1123504.JQKD01000023_gene161 1.029e-67 244.0 COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,2VHMT@28216|Betaproteobacteria,4AC2N@80864|Comamonadaceae 28216|Betaproteobacteria S Lipocalin-like domain - - - - - - - - - - - - CrtC,Lipocalin_9 SYD1_k127_3386748_51 1123392.AQWL01000006_gene573 1.76e-21 99.0 COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,2VU52@28216|Betaproteobacteria,1KT5Y@119069|Hydrogenophilales 119069|Hydrogenophilales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese SYD1_k127_3386748_41 1121413.JMKT01000009_gene2140 9.27e-44 177.0 COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,42RU4@68525|delta/epsilon subdivisions,2WNN7@28221|Deltaproteobacteria,2M9X3@213115|Desulfovibrionales 28221|Deltaproteobacteria O PFAM Cytochrome c assembly protein ccmC - - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - Cytochrom_C_asm SYD1_k127_3386748_56 479434.Sthe_1411 1.997e-17 98.0 COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi,27YCJ@189775|Thermomicrobia 189775|Thermomicrobia O CcmB protein - - - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB SYD1_k127_3386748_44 666686.B1NLA3E_15540 5.452e-39 153.0 COG1131@1|root,COG1131@2|Bacteria,1V7J1@1239|Firmicutes,4HJPG@91061|Bacilli,1ZPZ7@1386|Bacillus 91061|Bacilli V COG1131 ABC-type multidrug transport system, ATPase component - - 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - - ABC_tran SYD1_k127_3386748_54 309801.trd_0263 7.157e-19 102.0 COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi,27XRI@189775|Thermomicrobia 189775|Thermomicrobia C Cytochrome c - - - - - - - - - - - - CarboxypepD_reg SYD1_k127_3386748_57 635013.TherJR_2281 3.355e-09 69.0 COG3088@1|root,COG3088@2|Bacteria,1VETA@1239|Firmicutes,24TPT@186801|Clostridia,265EA@186807|Peptococcaceae 186801|Clostridia P subunit of a heme lyase - - - ko:K02200 - - - - ko00000 - - - CcmH SYD1_k127_3386748_6 204669.Acid345_3207 5e-177 581.0 COG1138@1|root,COG1138@2|Bacteria,3Y40N@57723|Acidobacteria,2JHQR@204432|Acidobacteriia 204432|Acidobacteriia O PFAM Cytochrome c assembly protein - - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm SYD1_k127_3386748_53 1382356.JQMP01000004_gene244 3.33e-19 93.0 COG2332@1|root,COG2332@2|Bacteria,2G7CS@200795|Chloroflexi,27YD4@189775|Thermomicrobia 189775|Thermomicrobia O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH - - - ko:K02197 - - - - ko00000 - - - CcmE SYD1_k127_3386748_24 575540.Isop_3270 8.329e-70 252.0 COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,2IXF2@203682|Planctomycetes 203682|Planctomycetes V beta-lactamase - - - - - - - - - - - - Beta-lactamase,DUF1343 SYD1_k127_3386748_58 1318628.MARLIPOL_02855 3.359e-08 64.0 COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RMUV@1236|Gammaproteobacteria,464V4@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction histidine kinase - - - - - - - - - - - - CHASE3,HAMP,HATPase_c,HisKA,PAS_3,PAS_9,dCache_1 SYD1_k127_3386748_33 661478.OP10G_1093 6.899e-57 205.0 COG2207@1|root,COG4312@1|root,COG2207@2|Bacteria,COG4312@2|Bacteria 2|Bacteria S Bacterial protein of unknown function (DUF899) - - - ko:K21701 - - - - ko00000,ko03000 - - - Arabinose_bd,DUF899,HTH_18 SYD1_k127_3386748_42 1142394.PSMK_27880 1.845e-41 175.0 COG2017@1|root,COG2017@2|Bacteria,2J49D@203682|Planctomycetes 203682|Planctomycetes G converts alpha-aldose to the beta-anomer - - - - - - - - - - - - - SYD1_k127_3386748_3 1254432.SCE1572_50080 2.72e-204 646.0 COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,43B0K@68525|delta/epsilon subdivisions,2X370@28221|Deltaproteobacteria,2YUMD@29|Myxococcales 28221|Deltaproteobacteria C Phosphoenolpyruvate phosphomutase aceA - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL SYD1_k127_3386748_1 448385.sce8725 5.219e-225 709.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,42P3R@68525|delta/epsilon subdivisions,2X349@28221|Deltaproteobacteria,2YU6W@29|Myxococcales 28221|Deltaproteobacteria H Malate synthase aceB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Hemerythrin,ICL,Malate_synthase SYD1_k127_3386748_9 1121033.AUCF01000003_gene3213 4.968e-141 462.0 COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,1MU50@1224|Proteobacteria,2TRKE@28211|Alphaproteobacteria,2JQ59@204441|Rhodospirillales 204441|Rhodospirillales K IrrE N-terminal-like domain - - - ko:K07110 - - - - ko00000,ko03000 - - - DUF2083,Peptidase_M78 SYD1_k127_3386748_38 1449126.JQKL01000036_gene1950 1.873e-45 186.0 COG2931@1|root,COG2931@2|Bacteria 2|Bacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - FG-GAP,HemolysinCabind SYD1_k127_3386748_18 391625.PPSIR1_16615 2.914e-90 310.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42S2J@68525|delta/epsilon subdivisions,2X7BN@28221|Deltaproteobacteria 28221|Deltaproteobacteria V ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SYD1_k127_3386748_30 523791.Kkor_1780 8.192e-58 218.0 COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,1PM1H@1224|Proteobacteria,1RUN8@1236|Gammaproteobacteria,1XQN3@135619|Oceanospirillales 135619|Oceanospirillales V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 SYD1_k127_3386748_4 204669.Acid345_4392 4.778e-203 661.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria 57723|Acidobacteria KLTU Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40,Pkinase SYD1_k127_3386748_13 1519464.HY22_13125 1.393e-121 418.0 COG0737@1|root,COG1520@1|root,COG0737@2|Bacteria,COG1520@2|Bacteria 2|Bacteria S amino acid activation for nonribosomal peptide biosynthetic process - - 3.4.17.18 ko:K05996 - - - - ko00000,ko01000,ko01002 - - - 5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH SYD1_k127_3386748_25 1173024.KI912148_gene3333 1.251e-69 264.0 COG0412@1|root,COG0412@2|Bacteria,1G1CY@1117|Cyanobacteria,1JJI9@1189|Stigonemataceae 1117|Cyanobacteria Q Dienelactone hydrolase family - - - - - - - - - - - - DLH SYD1_k127_3386748_50 292459.STH1141 9.513e-27 121.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - 3.4.11.19 ko:K01266,ko:K07052 - - - - ko00000,ko01000,ko01002 - - - Abi SYD1_k127_3386748_40 96561.Dole_1205 5.425e-44 175.0 COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,42T2P@68525|delta/epsilon subdivisions,2WPQ3@28221|Deltaproteobacteria,2MKI3@213118|Desulfobacterales 28221|Deltaproteobacteria S Cupin superfamily (DUF985) - - - ko:K09705 - - - - ko00000 - - - Cupin_5 SYD1_k127_3386748_35 1121920.AUAU01000006_gene301 2.471e-53 194.0 2BYAB@1|root,32R2Z@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_3386748_29 383372.Rcas_0525 1.101e-58 235.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia 32061|Chloroflexia KLT Serine threonine protein kinase - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8 SYD1_k127_3386748_10 1242864.D187_001830 2.236e-140 498.0 COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YWHV@29|Myxococcales 28221|Deltaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12 SYD1_k127_3386748_37 485916.Dtox_2819 1.628e-47 185.0 COG2223@1|root,COG2223@2|Bacteria,1TPTN@1239|Firmicutes,25EM4@186801|Clostridia,261F9@186807|Peptococcaceae 186801|Clostridia P PFAM Major Facilitator Superfamily - - - ko:K08223 - - - - ko00000,ko02000 2.A.1.35 - - MFS_1 SYD1_k127_3386748_11 255470.cbdbA861 6.689e-135 443.0 COG2309@1|root,COG2309@2|Bacteria,2G5TH@200795|Chloroflexi,34CT4@301297|Dehalococcoidia 301297|Dehalococcoidia E Thermophilic metalloprotease (M29) - - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 SYD1_k127_3386748_45 1297569.MESS2_490001 4.962e-33 137.0 COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,2U6ME@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C SYD1_k127_3386748_2 391625.PPSIR1_30065 4.912e-207 665.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,2YX5W@29|Myxococcales 28221|Deltaproteobacteria L DNA helicase - - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind SYD1_k127_3386748_63 1123276.KB893245_gene1230 1.639e-05 54.0 COG4319@1|root,COG4319@2|Bacteria,4NU3P@976|Bacteroidetes,47T7D@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 SYD1_k127_3386748_0 1121468.AUBR01000064_gene947 1.079e-303 946.0 COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24E00@186801|Clostridia,42FQ1@68295|Thermoanaerobacterales 186801|Clostridia I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C SYD1_k127_3386748_59 443144.GM21_1978 9.651e-08 59.0 COG3064@1|root,COG3064@2|Bacteria 2|Bacteria M translation initiation factor activity - - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - - SYD1_k127_3386748_65 404380.Gbem_2248 6.577e-05 52.0 COG3064@1|root,COG3064@2|Bacteria,1R7D3@1224|Proteobacteria,42Y44@68525|delta/epsilon subdivisions,2WT88@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Membrane - - - - - - - - - - - - - SYD1_k127_3447577_34 1366046.HIMB11_02272 2.328e-10 65.0 2CSD0@1|root,32SQY@2|Bacteria,1N16V@1224|Proteobacteria,2UCK3@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - SYD1_k127_3447577_21 1121946.AUAX01000019_gene7807 6.386e-31 126.0 COG3832@1|root,COG3832@2|Bacteria,2IIF0@201174|Actinobacteria,4DJFP@85008|Micromonosporales 201174|Actinobacteria J Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 SYD1_k127_3447577_25 251229.Chro_1586 5.362e-26 110.0 COG0640@1|root,COG0640@2|Bacteria,1G6T4@1117|Cyanobacteria,3VMWF@52604|Pleurocapsales 1117|Cyanobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20,HTH_5 SYD1_k127_3447577_4 404589.Anae109_1549 2.062e-129 442.0 COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,1MV1P@1224|Proteobacteria,42PPB@68525|delta/epsilon subdivisions,2X5YN@28221|Deltaproteobacteria,2YUEJ@29|Myxococcales 28221|Deltaproteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_10,TPR_12 SYD1_k127_3447577_24 1122201.AUAZ01000052_gene2649 3.252e-26 113.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1SDAD@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Integrase core domain - - - - - - - - - - - - rve,rve_3 SYD1_k127_3447577_8 596154.Alide2_1764 7.892e-94 319.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VHER@28216|Betaproteobacteria,4AGKJ@80864|Comamonadaceae 28216|Betaproteobacteria L PFAM Integrase catalytic - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_3 SYD1_k127_3447577_19 596154.Alide2_1765 2.03e-40 151.0 COG2963@1|root,COG2963@2|Bacteria,1N1AA@1224|Proteobacteria,2VU5U@28216|Betaproteobacteria,4AI0D@80864|Comamonadaceae 28216|Betaproteobacteria L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 SYD1_k127_3447577_36 221027.JO40_04435 5.791e-08 66.0 COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,2J6UE@203691|Spirochaetes 203691|Spirochaetes U Protein conserved in bacteria - - - - - - - - - - - - FlgD_ig SYD1_k127_3447577_18 1173027.Mic7113_0207 1.382e-40 153.0 COG4679@1|root,COG4679@2|Bacteria,1G675@1117|Cyanobacteria,1HBER@1150|Oscillatoriales 1117|Cyanobacteria S Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 SYD1_k127_3447577_26 1173027.Mic7113_0208 2.474e-23 104.0 COG5606@1|root,COG5606@2|Bacteria,1G7N5@1117|Cyanobacteria,1HCCE@1150|Oscillatoriales 1117|Cyanobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_37 SYD1_k127_3447577_28 1286106.MPL1_08444 3.733e-19 91.0 2D2Z4@1|root,32TDX@2|Bacteria,1MZK1@1224|Proteobacteria,1S9TU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - DUF3024 SYD1_k127_3447577_38 891968.Anamo_1745 2.295e-07 54.0 2A0EE@1|root,30NI4@2|Bacteria,3TCI5@508458|Synergistetes 508458|Synergistetes - - - - - - - - - - - - - - - SYD1_k127_3447577_11 1121957.ATVL01000014_gene1459 4.368e-74 278.0 COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - SYD1_k127_3447577_13 518766.Rmar_0744 1.46e-57 222.0 COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1FKAM@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes O Subtilase family - - - - - - - - - - - - Peptidase_S8 SYD1_k127_3447577_15 1338011.BD94_2865 4.187e-48 177.0 2CVTP@1|root,32SY9@2|Bacteria,4NUEJ@976|Bacteroidetes,1I4ZN@117743|Flavobacteriia,34S3X@308865|Elizabethkingia 976|Bacteroidetes S Protein of unknown function (DUF1203) - - - - - - - - - - - - DUF1203 SYD1_k127_3447577_5 671143.DAMO_0826 5.756e-111 386.0 COG3005@1|root,COG3005@2|Bacteria 2|Bacteria C denitrification pathway - - - ko:K02569,ko:K15876 ko00910,ko01120,map00910,map01120 M00530 R05712 RC00176 ko00000,ko00001,ko00002 - - - Cytochrom_NNT,Cytochrome_C7 SYD1_k127_3447577_12 1379698.RBG1_1C00001G0779 3.993e-64 249.0 COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria 2|Bacteria C Cytochrome c554 and c-prime - - - ko:K03620 ko02020,map02020 - - - ko00000,ko00001 - - - Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB SYD1_k127_3447577_17 330214.NIDE3889 3.09e-42 169.0 COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3J0Q6@40117|Nitrospirae 2|Bacteria C Cytochrome b/b6/petB qcrC - - ko:K00412,ko:K03888 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrome_B,Cytochrome_CBB3 SYD1_k127_3447577_29 935261.JAGL01000027_gene735 2.955e-18 91.0 COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1NARN@1224|Proteobacteria,2U22S@28211|Alphaproteobacteria,43JGD@69277|Phyllobacteriaceae 28211|Alphaproteobacteria CE Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - DAO,Rieske SYD1_k127_3447577_1 945713.IALB_1306 2.854e-225 733.0 COG2864@1|root,COG2864@2|Bacteria 2|Bacteria C formate dehydrogenase - - - - - - - - - - - - Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB SYD1_k127_3447577_7 1379698.RBG1_1C00001G0777 1.304e-105 352.0 COG2864@1|root,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria 2|Bacteria P Prokaryotic cytochrome b561 cbcY - - - - - - - - - - - Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese SYD1_k127_3447577_0 1379698.RBG1_1C00001G0777 1.865e-239 762.0 COG2864@1|root,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria 2|Bacteria P Prokaryotic cytochrome b561 cbcY - - - - - - - - - - - Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese SYD1_k127_3447577_23 561175.KB894102_gene1033 3.726e-27 123.0 COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4EMQS@85012|Streptosporangiales 201174|Actinobacteria T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg SYD1_k127_3447577_6 1125863.JAFN01000001_gene1650 3.815e-107 363.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria 28221|Deltaproteobacteria T two component, sigma54 specific, transcriptional regulator, Fis family ntrX - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_3447577_31 575540.Isop_1130 2.951e-16 88.0 COG0727@1|root,COG0727@2|Bacteria,2IZU5@203682|Planctomycetes 203682|Planctomycetes S PFAM Uncharacterised protein family (UPF0153) - - - - - - - - - - - - CxxCxxCC SYD1_k127_3447577_14 1051632.TPY_0663 2.363e-49 202.0 COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,248PD@186801|Clostridia 186801|Clostridia O Highly conserved protein containing a thioredoxin domain - - - ko:K06888 - - - - ko00000 - - - Thioredox_DsbH SYD1_k127_3447577_16 262724.TT_C0839 7.054e-44 170.0 COG2120@1|root,COG2120@2|Bacteria,1WIUY@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM GlcNAc-PI de-N-acetylase - - - ko:K01463 - - - - ko00000,ko01000 - - - PIG-L SYD1_k127_3447577_27 706587.Desti_4742 1.225e-19 95.0 2EH48@1|root,33AW7@2|Bacteria,1NIYU@1224|Proteobacteria,42XKK@68525|delta/epsilon subdivisions,2WSKU@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - SYD1_k127_3447577_10 1227739.Hsw_1264 1.417e-80 282.0 COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,47P2Z@768503|Cytophagia 976|Bacteroidetes S RelA SpoT domain protein - - - - - - - - - - - - GTA_TIM SYD1_k127_3447577_22 1379698.RBG1_1C00001G0750 2.454e-28 123.0 COG2143@1|root,COG2143@2|Bacteria 2|Bacteria O COG2143 Thioredoxin-related protein soxS - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - Thioredoxin_2,Thioredoxin_7 SYD1_k127_3447577_9 479434.Sthe_0322 2.902e-86 299.0 COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi,27XGT@189775|Thermomicrobia 189775|Thermomicrobia J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C SYD1_k127_3447577_35 913325.N799_10780 1.228e-09 69.0 COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,1X62K@135614|Xanthomonadales 135614|Xanthomonadales S Putative adhesin - - - - - - - - - - - - DUF4097 SYD1_k127_3447577_20 335543.Sfum_1967 1.447e-35 143.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,42TJK@68525|delta/epsilon subdivisions,2WQ0Z@28221|Deltaproteobacteria,2MRWJ@213462|Syntrophobacterales 28221|Deltaproteobacteria S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 SYD1_k127_3447577_3 706587.Desti_4421 2.994e-145 473.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,2MQ8K@213462|Syntrophobacterales 28221|Deltaproteobacteria L PFAM MgsA AAA ATPase C terminal rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N SYD1_k127_3447577_30 693977.Deipr_1519 1.475e-16 93.0 COG0477@1|root,COG2814@2|Bacteria,1WJDG@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1 SYD1_k127_3447577_2 485913.Krac_7836 2.766e-159 513.0 COG1960@1|root,COG1960@2|Bacteria,2G7JH@200795|Chloroflexi 200795|Chloroflexi C PFAM acyl-CoA dehydrogenase domain protein - - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N SYD1_k127_3447577_37 457570.Nther_2059 1.274e-07 62.0 COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia 186801|Clostridia T PFAM metal-dependent phosphohydrolase, HD sub domain - - - - - - - - - - - - HD,HD_5 SYD1_k127_3507285_5 1121098.HMPREF1534_01862 1.047e-67 249.0 COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,2FMNM@200643|Bacteroidia,4AMKJ@815|Bacteroidaceae 976|Bacteroidetes K Sigma-54 interaction domain protein fhlA - - - - - - - - - - - HTH_8,Sigma54_activat SYD1_k127_3507285_6 1489678.RDMS_10325 2.154e-54 204.0 COG1131@1|root,COG1131@2|Bacteria,1WJ0H@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus V ABC-type multidrug transport system ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SYD1_k127_3507285_15 1268239.PALB_21120 1.939e-30 139.0 COG4775@1|root,COG4775@2|Bacteria,1PT0R@1224|Proteobacteria,1RPWY@1236|Gammaproteobacteria,2Q0ZC@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M COG4775 Outer membrane protein protective antigen OMA87 - - - - - - - - - - - - Bac_surface_Ag,ShlB SYD1_k127_3507285_9 1379698.RBG1_1C00001G0694 1.207e-46 179.0 2AXD3@1|root,31PCE@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DinB,DinB_2 SYD1_k127_3507285_4 234267.Acid_2488 7.705e-72 251.0 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - - - - - - - - - - Methyltransf_25 SYD1_k127_3507285_13 2074.JNYD01000015_gene4489 2.472e-36 145.0 2BVXR@1|root,32QYG@2|Bacteria,2I832@201174|Actinobacteria,4EEBX@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - DoxX SYD1_k127_3507285_7 1429046.RR21198_0699 4.886e-54 200.0 COG2345@1|root,COG2345@2|Bacteria,2HCEF@201174|Actinobacteria,4FUCZ@85025|Nocardiaceae 201174|Actinobacteria K transcriptional regulator - - - - - - - - - - - - HTH_20 SYD1_k127_3507285_16 1267535.KB906767_gene4248 2.292e-22 104.0 COG2318@1|root,COG2318@2|Bacteria,3Y82J@57723|Acidobacteria,2JN4W@204432|Acidobacteriia 204432|Acidobacteriia S Protein of unknown function (DUF664) - - - - - - - - - - - - DinB_2 SYD1_k127_3507285_2 338966.Ppro_1962 8.103e-105 364.0 COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,42M82@68525|delta/epsilon subdivisions,2WKGK@28221|Deltaproteobacteria,43U0E@69541|Desulfuromonadales 28221|Deltaproteobacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - Fer4_14,Radical_SAM SYD1_k127_3507285_11 246197.MXAN_6280 4.108e-41 172.0 COG0793@1|root,COG3577@1|root,COG0793@2|Bacteria,COG3577@2|Bacteria,1N4T9@1224|Proteobacteria 1224|Proteobacteria M Aspartyl protease - - - - - - - - - - - - Asp_protease_2,PDZ_2 SYD1_k127_3507285_14 309807.SRU_1789 3.706e-33 136.0 2CDT7@1|root,2ZZ6E@2|Bacteria,4PERQ@976|Bacteroidetes,1FJHB@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes - - - - - - - - - - - - - - - SYD1_k127_3507285_0 861299.J421_1867 0.0 1371.0 COG1429@1|root,COG1429@2|Bacteria 2|Bacteria H ligase activity, forming nitrogen-metal bonds cobN - 6.6.1.2 ko:K02230 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - CobN-Mg_chel,Glyco_hydro_63 SYD1_k127_3507285_8 479434.Sthe_2438 4.956e-54 220.0 COG0363@1|root,COG0363@2|Bacteria,2G6S0@200795|Chloroflexi,27YBD@189775|Thermomicrobia 189775|Thermomicrobia G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase - - 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso SYD1_k127_3507285_10 105559.Nwat_1048 2.626e-42 180.0 COG4420@1|root,COG4420@2|Bacteria,1RIDY@1224|Proteobacteria,1S3IM@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Protein of unknown function (DUF1003) - - - - - - - - - - - - DUF1003 SYD1_k127_3507285_1 1496688.ER33_11555 8.171e-246 790.0 COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria,22THV@167375|Cyanobium 1117|Cyanobacteria G Amylo-alpha-1,6-glucosidase - - - - - - - - - - - - GDE_C,GDE_N SYD1_k127_3507285_17 1267533.KB906734_gene3853 1.297e-07 64.0 COG4272@1|root,COG4272@2|Bacteria 2|Bacteria S membrane ywjH - - - - - - - - - - - DUF1634 SYD1_k127_3507285_3 1297742.A176_02939 1.218e-96 331.0 COG0730@1|root,COG0730@2|Bacteria,1NJ47@1224|Proteobacteria,42QRS@68525|delta/epsilon subdivisions,2WN5M@28221|Deltaproteobacteria 28221|Deltaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE SYD1_k127_3507285_12 864702.OsccyDRAFT_4631 2.644e-37 157.0 COG2898@1|root,COG2898@2|Bacteria,1G1E7@1117|Cyanobacteria,1H7PX@1150|Oscillatoriales 1117|Cyanobacteria S 'Conserved protein - - 2.3.2.3 ko:K07027,ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.3.37,4.D.2 - - DUF2156,tRNA-synt_2_TM SYD1_k127_3551045_23 234267.Acid_5940 4.815e-14 72.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria 57723|Acidobacteria KLTU WD40 domain protein beta Propeller - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase SYD1_k127_3551045_1 1382306.JNIM01000001_gene736 8.187e-227 724.0 COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,2G83U@200795|Chloroflexi 200795|Chloroflexi P Voltage gated chloride channel - - - - - - - - - - - - CBS,Voltage_CLC SYD1_k127_3551045_17 1382356.JQMP01000003_gene2350 7.444e-28 119.0 COG1846@1|root,COG1846@2|Bacteria,2G8V5@200795|Chloroflexi 200795|Chloroflexi K Winged helix DNA-binding domain - - - - - - - - - - - - MarR_2 SYD1_k127_3551045_5 1463934.JOCF01000016_gene3723 2.698e-110 372.0 COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria 201174|Actinobacteria C Dehydrogenase - - 1.1.3.46 ko:K16422 ko00261,ko01055,ko01130,map00261,map01055,map01130 - R06633 RC00240 ko00000,ko00001,ko01000 - - - FMN_dh SYD1_k127_3551045_10 1267534.KB906754_gene3521 1.481e-69 248.0 COG2267@1|root,COG2267@2|Bacteria,3Y77N@57723|Acidobacteria,2JMKZ@204432|Acidobacteriia 204432|Acidobacteriia I Serine aminopeptidase, S33 - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 SYD1_k127_3551045_22 273075.Ta0875 4.183e-15 88.0 COG1280@1|root,arCOG01947@2157|Archaea,2XURC@28890|Euryarchaeota,24285@183967|Thermoplasmata 183967|Thermoplasmata E LysE type translocator - - - - - - - - - - - - LysE SYD1_k127_3551045_12 765420.OSCT_0333 8.332e-61 219.0 COG0745@1|root,COG0745@2|Bacteria,2GAPE@200795|Chloroflexi,375I7@32061|Chloroflexia 32061|Chloroflexia K Two component transcriptional regulator, winged helix family - - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C SYD1_k127_3551045_9 485913.Krac_0779 2.903e-82 291.0 COG0642@1|root,COG2205@2|Bacteria,2GBIC@200795|Chloroflexi 200795|Chloroflexi T histidine kinase A domain protein - - 2.7.13.3 ko:K02484,ko:K07642 ko02020,map02020 M00450,M00645,M00646,M00648 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA SYD1_k127_3551045_21 1385517.N800_12695 2.351e-17 94.0 COG3577@1|root,COG3577@2|Bacteria 2|Bacteria S aspartic-type endopeptidase activity - - - - - - - - - - - - Asp_protease_2 SYD1_k127_3551045_11 1123393.KB891316_gene1800 1.117e-63 233.0 COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,2WBSA@28216|Betaproteobacteria,1KSGD@119069|Hydrogenophilales 119069|Hydrogenophilales M Thrombospondin type 3 repeat - - - - - - - - - - - - OmpA,TSP_3 SYD1_k127_3551045_20 861299.J421_0797 4.809e-21 106.0 COG0671@1|root,COG0671@2|Bacteria 2|Bacteria I phosphatidate phosphatase activity dgkA - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 ko:K00901,ko:K01096,ko:K19302 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02029,R02240,R05627 RC00002,RC00017 ko00000,ko00001,ko01000,ko01011 - - iAF987.Gmet_2369 DAGK_prokar,PAP2,PAP2_3 SYD1_k127_3551045_18 1192034.CAP_7220 1.879e-26 113.0 COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,42TZA@68525|delta/epsilon subdivisions,2WRHK@28221|Deltaproteobacteria,2Z03M@29|Myxococcales 28221|Deltaproteobacteria S CoA binding domain - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 SYD1_k127_3551045_6 1207063.P24_14749 5.317e-104 352.0 COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,2JPEG@204441|Rhodospirillales 204441|Rhodospirillales FL 6-O-methylguanine DNA methyltransferase, DNA binding domain - - 2.1.1.63 ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N SYD1_k127_3551045_0 1120973.AQXL01000133_gene1776 2.967e-237 753.0 COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,4H9ZS@91061|Bacilli,2783C@186823|Alicyclobacillaceae 91061|Bacilli O Protein of unknown function, DUF255 yyaL - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Glyco_hydro_9,Thioredox_DsbH SYD1_k127_3551045_7 1123368.AUIS01000004_gene259 1.761e-94 323.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,2NCI8@225057|Acidithiobacillales 225057|Acidithiobacillales J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans SYD1_k127_3551045_4 646529.Desaci_3461 8.701e-117 389.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25ZZ7@186807|Peptococcaceae 186801|Clostridia E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 SYD1_k127_3551045_14 278957.ABEA03000080_gene3199 1.74e-53 199.0 COG0652@1|root,COG0652@2|Bacteria,46VEN@74201|Verrucomicrobia,3K93U@414999|Opitutae 414999|Opitutae O Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - - - - - - - - - - Pro_isomerase SYD1_k127_3551045_28 545694.TREPR_2623 7.959e-08 66.0 COG0457@1|root,COG0457@2|Bacteria,2J5NB@203691|Spirochaetes 203691|Spirochaetes S tetratricopeptide repeat lmp1 - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8 SYD1_k127_3551045_19 1128427.KB904821_gene2528 4.387e-22 108.0 COG0457@1|root,COG0457@2|Bacteria,1G39E@1117|Cyanobacteria,1H8XZ@1150|Oscillatoriales 1117|Cyanobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_11,TPR_2,TPR_8 SYD1_k127_3551045_2 309801.trd_A0017 4.01e-147 483.0 COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia 189775|Thermomicrobia O Magnesium chelatase, subunit ChlI - - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C SYD1_k127_3551045_13 1123508.JH636440_gene2626 1.835e-54 201.0 COG5662@1|root,COG5662@2|Bacteria 2|Bacteria K AntiSigma factor - - - - - - - - - - - - zf-HC2 SYD1_k127_3551045_15 497964.CfE428DRAFT_4052 4.768e-47 177.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SYD1_k127_3551045_26 710685.MycrhN_2748 4.216e-09 69.0 COG4454@1|root,COG4454@2|Bacteria,2GS6Z@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - Copper-bind,Cupredoxin_1 SYD1_k127_3551045_25 1046724.KB889933_gene1060 1.103e-10 74.0 COG3794@1|root,COG3794@2|Bacteria 2|Bacteria C PFAM blue (type 1) copper domain protein - - 2.4.1.109 ko:K00728 ko00514,ko00515,ko01100,map00514,map00515,map01100 - R04072,R07620,R11399 RC00005,RC00059,RC00397 ko00000,ko00001,ko01000,ko01003 - GT39 - LytR_C,LytR_cpsA_psr,PMT_2,PMT_4TMC SYD1_k127_3551045_27 382464.ABSI01000002_gene4348 4.556e-09 69.0 COG1011@1|root,COG1011@2|Bacteria,46T57@74201|Verrucomicrobia,2IUUA@203494|Verrucomicrobiae 203494|Verrucomicrobiae S HAD-hyrolase-like - - - - - - - - - - - - HAD_2 SYD1_k127_3551045_16 1448860.BBJO01000005_gene2443 1.378e-31 136.0 COG1893@1|root,arCOG04139@2157|Archaea,2XTBD@28890|Euryarchaeota,23T98@183963|Halobacteria 183963|Halobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C SYD1_k127_3551045_24 459349.CLOAM1790 5.202e-11 78.0 COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria 2|Bacteria K Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS SYD1_k127_3551045_8 1379698.RBG1_1C00001G0584 1.53e-91 342.0 COG2373@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria 2|Bacteria G gluconolactonase activity - - 3.4.24.40 ko:K01406,ko:K14274,ko:K20276,ko:K21449 ko00040,ko01503,ko02024,map00040,map01503,map02024 - R02427 RC00713 ko00000,ko00001,ko01000,ko01002,ko02000 1.B.40.2 - - Calx-beta,DUF4347,He_PIG,Ice_nucleation,SGL SYD1_k127_3551045_3 1379698.RBG1_1C00001G0516 4.147e-141 465.0 COG0473@1|root,COG0473@2|Bacteria,2NP1R@2323|unclassified Bacteria 2|Bacteria CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh SYD1_k127_3580118_13 237368.SCABRO_00273 7.612e-27 126.0 COG4972@1|root,COG4972@2|Bacteria,2IZC6@203682|Planctomycetes 203682|Planctomycetes NU pilus assembly protein - - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 SYD1_k127_3580118_12 1121406.JAEX01000009_gene2589 3.324e-31 127.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2M7S0@213115|Desulfovibrionales 28221|Deltaproteobacteria T PFAM response regulator receiver phoB - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C SYD1_k127_3580118_1 643473.KB235930_gene4490 4.946e-142 465.0 COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,1G0T4@1117|Cyanobacteria,1HM63@1161|Nostocales 1117|Cyanobacteria EK Pyridoxal-phosphate dependent enzyme - - 4.2.1.22 ko:K01697 ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230 M00035,M00338 R00891,R01290,R04942 RC00056,RC00069,RC00256,RC00489,RC01246 ko00000,ko00001,ko00002,ko01000 - - - CBS,PALP SYD1_k127_3580118_2 1345697.M493_13170 1.823e-138 471.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1WF6Y@129337|Geobacillus 91061|Bacilli E Cys/Met metabolism PLP-dependent enzyme mccB GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27250 Cys_Met_Meta_PP SYD1_k127_3580118_9 635013.TherJR_1429 1.561e-59 211.0 COG1666@1|root,COG1666@2|Bacteria,1V3UR@1239|Firmicutes,24HUX@186801|Clostridia,261V6@186807|Peptococcaceae 186801|Clostridia S Belongs to the UPF0234 family - - - ko:K09767 - - - - ko00000 - - - DUF520 SYD1_k127_3580118_11 234267.Acid_0973 5.085e-36 147.0 COG1512@1|root,COG1512@2|Bacteria,3Y4JT@57723|Acidobacteria 57723|Acidobacteria S TPM domain - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase SYD1_k127_3580118_15 56780.SYN_00536 1.472e-16 89.0 COG1708@1|root,COG1708@2|Bacteria,1NMP8@1224|Proteobacteria,42Y4J@68525|delta/epsilon subdivisions,2WSMP@28221|Deltaproteobacteria 28221|Deltaproteobacteria S nucleotidyltransferase activity - - - - - - - - - - - - - SYD1_k127_3580118_8 56780.SYN_00535 8.997e-60 214.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42R4C@68525|delta/epsilon subdivisions,2WKG9@28221|Deltaproteobacteria,2MS0Z@213462|Syntrophobacterales 28221|Deltaproteobacteria S LemA family - - - ko:K03744 - - - - ko00000 - - - LemA SYD1_k127_3580118_10 1123060.JONP01000003_gene350 1.42e-46 193.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2TT3G@28211|Alphaproteobacteria,2JQH9@204441|Rhodospirillales 204441|Rhodospirillales H TonB-dependent receptor - - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec SYD1_k127_3580118_7 172088.AUGA01000002_gene6122 4.707e-83 285.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2VF1S@28211|Alphaproteobacteria,3K6DC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 SYD1_k127_3580118_6 1379858.N508_00593 2.145e-112 388.0 COG0183@1|root,COG0183@2|Bacteria,2GEW2@200930|Deferribacteres 200930|Deferribacteres I Thiolase, C-terminal domain - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N SYD1_k127_3580118_5 316274.Haur_1203 1.945e-119 389.0 COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi 200795|Chloroflexi C 3-hydroxyacyl-CoA dehydrogenase domain protein - - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N SYD1_k127_3580118_4 1379698.RBG1_1C00001G0508 1.139e-129 425.0 COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria 2|Bacteria I Belongs to the thiolase family bktB - 2.3.1.16,2.3.1.9 ko:K00626,ko:K07508 ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00085,M00087,M00088,M00095,M00373,M00374,M00375 R00238,R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747 RC00004,RC00326,RC00405,RC01702 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N SYD1_k127_3580118_3 1379698.RBG1_1C00001G0513 3.817e-136 465.0 COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria 2|Bacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA3 - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like SYD1_k127_3580118_0 1379698.RBG1_1C00001G0516 1.692e-144 466.0 COG0473@1|root,COG0473@2|Bacteria,2NP1R@2323|unclassified Bacteria 2|Bacteria CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh SYD1_k127_3580118_14 1121272.KB903292_gene3732 2.345e-17 85.0 COG1285@1|root,COG1285@2|Bacteria,2GJF0@201174|Actinobacteria,4DDK5@85008|Micromonosporales 201174|Actinobacteria S MgtC family mgtC - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC SYD1_k127_3699653_39 861299.J421_0972 8.344e-126 407.0 COG1297@1|root,COG1297@2|Bacteria 2|Bacteria S iron-nicotianamine transmembrane transporter activity oliA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - - - - - - - - - - OPT SYD1_k127_3699653_117 1121456.ATVA01000016_gene1958 1.745e-31 132.0 COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,43BTI@68525|delta/epsilon subdivisions,2X74F@28221|Deltaproteobacteria,2MCV3@213115|Desulfovibrionales 28221|Deltaproteobacteria M Chalcone isomerase-like - - - - - - - - - - - - Chalcone_3 SYD1_k127_3699653_85 1380347.JNII01000009_gene2243 3.064e-63 220.0 COG1832@1|root,COG1832@2|Bacteria,2IJYY@201174|Actinobacteria 201174|Actinobacteria S PFAM CoA-binding domain protein - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 SYD1_k127_3699653_120 411154.GFO_1878 3.491e-31 141.0 COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1HXKD@117743|Flavobacteriia 976|Bacteroidetes M peptidase M23 - - - - - - - - - - - - Peptidase_M23 SYD1_k127_3699653_149 380749.HY04AAS1_0735 1.764e-11 72.0 COG0071@1|root,COG0071@2|Bacteria,2G4AZ@200783|Aquificae 200783|Aquificae O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 SYD1_k127_3699653_162 1262449.CP6013_3163 0.000262 54.0 COG1067@1|root,COG1067@2|Bacteria,1TP2K@1239|Firmicutes,247TX@186801|Clostridia,36E4T@31979|Clostridiaceae 186801|Clostridia O Belongs to the peptidase S16 family lonC - 3.4.21.53 ko:K01338,ko:K04076 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,Lon_C,RuvB_N SYD1_k127_3699653_125 591157.SSLG_03720 3.434e-27 125.0 COG2520@1|root,COG2520@2|Bacteria,2I388@201174|Actinobacteria 201174|Actinobacteria J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 SYD1_k127_3699653_161 309807.SRU_2822 0.0001243 51.0 COG2968@1|root,COG2968@2|Bacteria,4P8H6@976|Bacteroidetes,1FJN4@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Membrane - - - - - - - - - - - - OMP_b-brl SYD1_k127_3699653_93 1049564.TevJSym_aa00830 3.298e-50 184.0 COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,1S5B7@1236|Gammaproteobacteria,1J71P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Las17-binding protein actin regulator - - - - - - - - - - - - Ysc84 SYD1_k127_3699653_56 580332.Slit_1984 2.47e-95 316.0 COG2085@1|root,COG2085@2|Bacteria,1NI54@1224|Proteobacteria,2VNIB@28216|Betaproteobacteria 28216|Betaproteobacteria S PFAM NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored SYD1_k127_3699653_113 102129.Lepto7375DRAFT_5774 3.531e-34 138.0 COG3350@1|root,COG3350@2|Bacteria,1G6RV@1117|Cyanobacteria,1HBTF@1150|Oscillatoriales 1117|Cyanobacteria S Yhs domain-containing protein - - - - - - - - - - - - YHS SYD1_k127_3699653_62 384765.SIAM614_17934 6.163e-89 303.0 COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,2TW52@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator, AraC family - - - - - - - - - - - - Cupin_6,HTH_18 SYD1_k127_3699653_136 1158345.JNLL01000001_gene136 2.926e-21 108.0 COG3411@1|root,COG3411@2|Bacteria,2G541@200783|Aquificae 200783|Aquificae C Ferredoxin - - - - - - - - - - - - 2Fe-2S_thioredx SYD1_k127_3699653_71 690850.Desaf_3380 2.28e-73 267.0 COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,42N1Q@68525|delta/epsilon subdivisions,2WJJS@28221|Deltaproteobacteria,2MA1B@213115|Desulfovibrionales 28221|Deltaproteobacteria Q O-methyltransferase, family 2 - - - - - - - - - - - - Dimerisation2,Methyltransf_2 SYD1_k127_3699653_47 485916.Dtox_1611 1.03e-113 374.0 COG0535@1|root,COG0535@2|Bacteria,1URM8@1239|Firmicutes,24XB8@186801|Clostridia 186801|Clostridia C 4Fe-4S single cluster domain - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM SYD1_k127_3699653_9 204669.Acid345_4392 3.169e-191 629.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria 57723|Acidobacteria KLTU Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40,Pkinase SYD1_k127_3699653_80 1144275.COCOR_01387 8.077e-70 249.0 COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,42PQH@68525|delta/epsilon subdivisions,2WM5W@28221|Deltaproteobacteria,2YWUY@29|Myxococcales 28221|Deltaproteobacteria C Zinc-binding dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 SYD1_k127_3699653_121 1128421.JAGA01000003_gene2823 4.513e-30 126.0 COG2606@1|root,COG2606@2|Bacteria,2NPZ1@2323|unclassified Bacteria 2|Bacteria S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit SYD1_k127_3699653_1 159087.Daro_0245 5.376e-257 869.0 COG4625@1|root,COG4625@2|Bacteria,1N4H5@1224|Proteobacteria,2VPI3@28216|Betaproteobacteria 28216|Betaproteobacteria N protein with a C-terminal OMP (outer membrane protein) domain - - - - - - - - - - - - Autotransporter SYD1_k127_3699653_60 1206733.BAGC01000043_gene590 1.093e-91 314.0 2A201@1|root,30Q9W@2|Bacteria,2I8N1@201174|Actinobacteria,4G5YQ@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - SYD1_k127_3699653_32 652103.Rpdx1_3644 1.213e-131 440.0 COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,2U3P9@28211|Alphaproteobacteria,3JRA5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin SYD1_k127_3699653_99 706587.Desti_0642 1.559e-48 179.0 COG2764@1|root,COG2764@2|Bacteria,1PGQC@1224|Proteobacteria,4376D@68525|delta/epsilon subdivisions,2X25Y@28221|Deltaproteobacteria,2MSCE@213462|Syntrophobacterales 28221|Deltaproteobacteria S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase SYD1_k127_3699653_88 880073.Calab_0491 4.097e-56 201.0 COG1881@1|root,COG1881@2|Bacteria,2NPDK@2323|unclassified Bacteria 2|Bacteria S Phosphatidylethanolamine-binding protein - - - ko:K06910 - - - - ko00000 - - - PBP SYD1_k127_3699653_128 404589.Anae109_2532 2.571e-26 110.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2Z1SJ@29|Myxococcales 28221|Deltaproteobacteria K Cold shock protein - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD SYD1_k127_3699653_94 472759.Nhal_1889 4.955e-50 188.0 COG0778@1|root,COG0778@2|Bacteria,1RJMP@1224|Proteobacteria,1T0ZH@1236|Gammaproteobacteria,1X0TI@135613|Chromatiales 135613|Chromatiales C Nitroreductase family - - - - - - - - - - - - Nitroreductase SYD1_k127_3699653_34 1379698.RBG1_1C00001G0607 3.103e-131 447.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria 2|Bacteria T Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase,TPR_2,TPR_8 SYD1_k127_3699653_25 926550.CLDAP_18370 3.922e-139 448.0 COG2897@1|root,COG2897@2|Bacteria,2G5XI@200795|Chloroflexi 200795|Chloroflexi P PFAM Rhodanese domain protein - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese SYD1_k127_3699653_109 1278073.MYSTI_02804 2.154e-37 161.0 COG3420@1|root,COG3420@2|Bacteria 2|Bacteria P alginic acid biosynthetic process - - 4.2.2.3 ko:K01729 ko00051,map00051 - R03706 - ko00000,ko00001,ko01000 - - - Beta_helix,Chondroitinas_B SYD1_k127_3699653_146 870187.Thini_3057 1.523e-13 85.0 COG2885@1|root,COG2931@1|root,COG2885@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,463V5@72273|Thiotrichales 72273|Thiotrichales Q COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - - SYD1_k127_3699653_123 1124780.ANNU01000006_gene2954 6.566e-28 133.0 COG1409@1|root,COG3595@1|root,COG4099@1|root,COG4932@1|root,COG1409@2|Bacteria,COG3595@2|Bacteria,COG4099@2|Bacteria,COG4932@2|Bacteria,4NFSH@976|Bacteroidetes,47REE@768503|Cytophagia 976|Bacteroidetes M Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_2,Peptidase_S9 SYD1_k127_3699653_141 880073.Calab_3296 1.181e-16 96.0 COG0737@1|root,COG0737@2|Bacteria 2|Bacteria F nucleotide catabolic process - - 3.4.17.18 ko:K05996 - - - - ko00000,ko01000,ko01002 - - - 5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH SYD1_k127_3699653_29 926550.CLDAP_22570 1.919e-137 448.0 COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi 200795|Chloroflexi K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template - - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_RNA_bind SYD1_k127_3699653_116 926569.ANT_29070 1.705e-32 132.0 COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi 200795|Chloroflexi P PFAM Rhodanese domain protein - - - - - - - - - - - - Rhodanese SYD1_k127_3699653_38 877455.Metbo_0048 8.328e-128 422.0 COG0477@1|root,arCOG02682@2157|Archaea,2XWP6@28890|Euryarchaeota,23PB6@183925|Methanobacteria 183925|Methanobacteria G Sugar (and other) transporter - - - - - - - - - - - - - SYD1_k127_3699653_82 1123242.JH636434_gene5626 3.147e-66 239.0 COG4886@1|root,COG5426@1|root,COG4886@2|Bacteria,COG5426@2|Bacteria 2|Bacteria D von Willebrand factor, type A - - - - - - - - - - - - DUF285,Flg_new,LRR_5,LRR_6 SYD1_k127_3699653_147 1082931.KKY_2436 1.841e-13 72.0 2EFVW@1|root,339N3@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_3699653_51 1444309.JAQG01000033_gene2967 5.482e-101 342.0 COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,26R2G@186822|Paenibacillaceae 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA_2 - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase SYD1_k127_3699653_157 459349.CLOAM1314 1.887e-07 64.0 COG0457@1|root,COG1462@1|root,COG0457@2|Bacteria,COG1462@2|Bacteria 2|Bacteria M curli production assembly transport component CsgG - - - - - - - - - - - - CsgG SYD1_k127_3699653_13 388413.ALPR1_09073 4.284e-176 562.0 COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,47JIN@768503|Cytophagia 976|Bacteroidetes C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt SYD1_k127_3699653_7 1047013.AQSP01000105_gene1443 1.252e-210 699.0 COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria 2|Bacteria M Tricorn protease C1 domain - - - ko:K08676 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ SYD1_k127_3699653_42 204669.Acid345_4167 1.44e-121 417.0 COG1520@1|root,COG1520@2|Bacteria,3Y2H2@57723|Acidobacteria,2JM3H@204432|Acidobacteriia 204432|Acidobacteriia S PQQ-like domain - - 1.1.2.6 ko:K05889 - - R03136 - ko00000,ko01000 - - - PQQ_3 SYD1_k127_3699653_40 493475.GARC_2786 1.347e-122 407.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,466RG@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family macA - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 SYD1_k127_3699653_58 1191523.MROS_2282 3.045e-94 316.0 COG1136@1|root,COG1136@2|Bacteria 2|Bacteria V lipoprotein transporter activity macB - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SYD1_k127_3699653_22 493475.GARC_2784 3.575e-148 480.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,468D5@72275|Alteromonadaceae 1236|Gammaproteobacteria V MacB-like periplasmic core domain VP1997 - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SYD1_k127_3699653_18 493475.GARC_2783 1.104e-159 513.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,468D5@72275|Alteromonadaceae 1236|Gammaproteobacteria V MacB-like periplasmic core domain VP1997 - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SYD1_k127_3699653_27 756272.Plabr_3432 3.079e-138 449.0 COG4260@1|root,COG4260@2|Bacteria,2IYIR@203682|Planctomycetes 203682|Planctomycetes S virion core protein (lumpy skin disease virus) - - - - - - - - - - - - Band_7_1,DUF4339 SYD1_k127_3699653_115 502025.Hoch_4700 1.168e-33 145.0 COG3809@1|root,COG3809@2|Bacteria,1QJZM@1224|Proteobacteria,43E52@68525|delta/epsilon subdivisions,2X98E@28221|Deltaproteobacteria,2Z2KB@29|Myxococcales 28221|Deltaproteobacteria S Transcription factor zinc-finger - - - - - - - - - - - - zf-TFIIB SYD1_k127_3699653_68 1463887.KL590085_gene537 2.954e-77 275.0 COG1361@1|root,COG2706@1|root,COG1361@2|Bacteria,COG2706@2|Bacteria 2|Bacteria G 6-phosphogluconolactonase activity - - - - - - - - - - - - DUF11,VCBS SYD1_k127_3699653_127 1231190.NA8A_23839 1.876e-26 121.0 COG0662@1|root,COG0662@2|Bacteria,1RJ7D@1224|Proteobacteria,2UAG4@28211|Alphaproteobacteria,43PJI@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 SYD1_k127_3699653_31 1191523.MROS_0749 1.856e-132 437.0 COG0535@1|root,COG0535@2|Bacteria 2|Bacteria I radical SAM domain protein - - - - - - - - - - - - Fer4_12,Fer4_14,Radical_SAM,SPASM SYD1_k127_3699653_12 1123401.JHYQ01000026_gene3280 2.025e-179 572.0 COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,1RNTW@1236|Gammaproteobacteria,4605D@72273|Thiotrichales 72273|Thiotrichales F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT - 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp,Epimerase SYD1_k127_3699653_106 1179773.BN6_51740 3.77e-40 162.0 2EFIY@1|root,339BC@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_3699653_132 290397.Adeh_2005 1.642e-23 112.0 COG0509@1|root,COG0509@2|Bacteria,1RC80@1224|Proteobacteria,42R79@68525|delta/epsilon subdivisions,2WN04@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Glycine cleavage H-protein - - - - - - - - - - - - GCV_H SYD1_k127_3699653_54 1168034.FH5T_01630 8.536e-98 328.0 COG0437@1|root,COG0437@2|Bacteria,4NIEP@976|Bacteroidetes 976|Bacteroidetes C 4Fe-4S binding domain - - - - - - - - - - - - Fer4_11,Fer4_4 SYD1_k127_3699653_17 1168034.FH5T_01625 2.883e-162 524.0 COG5557@1|root,COG5557@2|Bacteria 2|Bacteria C Polysulphide reductase, NrfD hmcC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - NrfD SYD1_k127_3699653_105 290397.Adeh_2005 2.397e-41 174.0 COG0509@1|root,COG0509@2|Bacteria,1RC80@1224|Proteobacteria,42R79@68525|delta/epsilon subdivisions,2WN04@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Glycine cleavage H-protein - - - - - - - - - - - - GCV_H SYD1_k127_3699653_143 177437.HRM2_46800 3.883e-15 89.0 COG0509@1|root,COG0509@2|Bacteria,1RC80@1224|Proteobacteria,42R79@68525|delta/epsilon subdivisions,2WN04@28221|Deltaproteobacteria,2MJJZ@213118|Desulfobacterales 28221|Deltaproteobacteria E Glycine cleavage H-protein - - - - - - - - - - - - GCV_H SYD1_k127_3699653_53 234267.Acid_4206 2.545e-98 345.0 COG4191@1|root,COG4191@2|Bacteria,3Y42C@57723|Acidobacteria 57723|Acidobacteria T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K02482 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA SYD1_k127_3699653_16 945713.IALB_2429 8.128e-168 543.0 COG2204@1|root,COG2204@2|Bacteria 2|Bacteria T phosphorelay signal transduction system - - - ko:K02481,ko:K07713,ko:K07714 ko02020,map02020 M00499,M00500 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_3699653_112 880072.Desac_0991 1.347e-34 140.0 COG1913@1|root,COG1913@2|Bacteria,1NEU5@1224|Proteobacteria,42WCP@68525|delta/epsilon subdivisions,2X5BA@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Peptidase family M54 - - - ko:K06974 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M54 SYD1_k127_3699653_44 1121918.ARWE01000001_gene3081 1.469e-118 409.0 COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,43V7G@69541|Desulfuromonadales 28221|Deltaproteobacteria C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - 1.2.7.1,1.2.7.7 ko:K00170,ko:K00187 ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R07160,R08034,R08566,R08567 RC00004,RC00250,RC02742,RC02833,RC02856 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C SYD1_k127_3699653_28 1121918.ARWE01000001_gene3080 1.063e-137 458.0 COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,43TT3@69541|Desulfuromonadales 68525|delta/epsilon subdivisions C Pyruvate:ferredoxin oxidoreductase core domain II - - 1.2.7.1 ko:K00169 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR_N SYD1_k127_3699653_5 1121918.ARWE01000001_gene3079 3.82e-232 744.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria,43TQJ@69541|Desulfuromonadales 28221|Deltaproteobacteria E HI0933-like protein - - - - - - - - - - - - Fer4,Fer4_20,Fer4_9,Pyr_redox_2 SYD1_k127_3699653_138 1454007.JAUG01000024_gene824 7.369e-20 100.0 2CK2Y@1|root,32SBF@2|Bacteria,4NTZD@976|Bacteroidetes,1ITGQ@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Photosynthetic reaction centre cytochrome C subunit - - - ko:K13992 - - - - ko00000,ko00194 - - - CytoC_RC SYD1_k127_3699653_151 983544.Lacal_2774 4.357e-10 70.0 COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,4NHVF@976|Bacteroidetes,1HZ8C@117743|Flavobacteriia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase,DUF3471,TPR_2 SYD1_k127_3699653_119 666681.M301_2056 2.969e-31 134.0 2DSHY@1|root,33G71@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_3699653_131 523791.Kkor_1114 5.992e-24 115.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XM5A@135619|Oceanospirillales 135619|Oceanospirillales K cold-shock protein cspG - - ko:K03704 - - - - ko00000,ko03000 - - - CSD SYD1_k127_3699653_11 869210.Marky_1927 3.143e-180 592.0 COG0076@1|root,COG0076@2|Bacteria,1WKXN@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E COG0076 Glutamate decarboxylase and related PLP-dependent - - 4.1.1.105,4.1.1.28 ko:K01593 ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00037,M00042 R00685,R00699,R00736,R02080,R02701,R04909 RC00299 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyridoxal_deC SYD1_k127_3699653_97 1267535.KB906767_gene3861 2.735e-49 182.0 COG4103@1|root,COG4103@2|Bacteria 2|Bacteria T Tellurite resistance protein TerB - - - - - - - - - - - - TerB SYD1_k127_3699653_26 1379698.RBG1_1C00001G0765 1.79e-138 452.0 COG2132@1|root,COG2132@2|Bacteria,2NPCW@2323|unclassified Bacteria 2|Bacteria PQ Multicopper oxidase aniA - 1.7.2.1 ko:K00368 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1 SYD1_k127_3699653_33 1519464.HY22_13125 1.434e-131 445.0 COG0737@1|root,COG1520@1|root,COG0737@2|Bacteria,COG1520@2|Bacteria 2|Bacteria S amino acid activation for nonribosomal peptide biosynthetic process - - 3.4.17.18 ko:K05996 - - - - ko00000,ko01000,ko01002 - - - 5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH SYD1_k127_3699653_100 713586.KB900536_gene2816 3.986e-48 179.0 COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,1S6SD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S dioxygenase of extradiol dioxygenase family - - - ko:K06991 - - - - ko00000 - - - Glyoxalase SYD1_k127_3699653_46 1303518.CCALI_01109 2.02e-114 382.0 COG0665@1|root,COG0665@2|Bacteria 2|Bacteria E tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - 1.5.3.1 ko:K00303 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO SYD1_k127_3699653_59 1121405.dsmv_0956 1.996e-92 323.0 COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,42SUF@68525|delta/epsilon subdivisions,2WPJU@28221|Deltaproteobacteria,2MKU8@213118|Desulfobacterales 28221|Deltaproteobacteria E Ornithine cyclodeaminase/mu-crystallin family - - 1.4.1.1,4.3.1.12 ko:K01750,ko:K19244 ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230 - R00396,R00671 RC00008,RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall SYD1_k127_3699653_20 215803.DB30_2841 6.399e-152 529.0 COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42PT2@68525|delta/epsilon subdivisions,2WJ6Q@28221|Deltaproteobacteria,2YWF8@29|Myxococcales 28221|Deltaproteobacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_3 SYD1_k127_3699653_14 187272.Mlg_2744 6.919e-173 570.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1X14V@135613|Chromatiales 135613|Chromatiales S MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL SYD1_k127_3699653_101 1379698.RBG1_1C00001G0565 3.4e-46 192.0 COG2834@1|root,COG2834@2|Bacteria,2NQJ8@2323|unclassified Bacteria 2|Bacteria M Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - DUF4292,DUF4367,LolA_like SYD1_k127_3699653_76 1121920.AUAU01000004_gene643 1.151e-70 246.0 2CAZH@1|root,2Z7RU@2|Bacteria,3Y4WA@57723|Acidobacteria 57723|Acidobacteria - - - - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt SYD1_k127_3699653_0 903818.KI912268_gene1007 0.0 1028.0 COG1053@1|root,COG1053@2|Bacteria,3Y2MQ@57723|Acidobacteria 57723|Acidobacteria C Succinate dehydrogenase or fumarate reductase, flavoprotein subunit - - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C SYD1_k127_3699653_45 1121920.AUAU01000004_gene645 6.752e-118 412.0 COG0479@1|root,COG0479@2|Bacteria,3Y3XR@57723|Acidobacteria 57723|Acidobacteria C 2Fe-2S iron-sulfur cluster binding domain - - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_7,Fer4_8 SYD1_k127_3699653_139 582515.KR51_00020840 8.746e-19 102.0 COG1572@1|root,COG1864@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1GQ08@1117|Cyanobacteria 1117|Cyanobacteria F YD repeat - - - - - - - - - - - - CARDB,Calx-beta,PKD,RHS_repeat SYD1_k127_3699653_160 880073.Calab_0041 1.51e-05 58.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - 1.14.18.1 ko:K00505 ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916 M00042 R00731,R02078,R02363,R02383,R04693,R04884 RC00046,RC00150,RC00180 ko00000,ko00001,ko00002,ko01000 - - - BNR,FlgD_ig,Peptidase_S74,Tyrosinase SYD1_k127_3699653_21 1033734.CAET01000065_gene2231 1.125e-150 511.0 COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,4HEYP@91061|Bacilli,1ZM4F@1386|Bacillus 91061|Bacilli E Beta-eliminating lyase - - - - - - - - - - - - Beta_elim_lyase SYD1_k127_3699653_153 1121405.dsmv_1567 7.253e-09 61.0 2BWVJ@1|root,33YN1@2|Bacteria,1NXTC@1224|Proteobacteria,430BZ@68525|delta/epsilon subdivisions,2WVZK@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - SYD1_k127_3699653_108 861299.J421_0340 1.807e-37 153.0 COG3595@1|root,COG3595@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4097,PA14 SYD1_k127_3699653_30 379066.GAU_3326 3.767e-137 457.0 COG2081@1|root,COG2081@2|Bacteria,1ZUAT@142182|Gemmatimonadetes 142182|Gemmatimonadetes S HI0933-like protein - - - ko:K07007 - - - - ko00000 - - - HI0933_like SYD1_k127_3699653_79 404380.Gbem_0264 2.883e-70 246.0 COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria,42RS2@68525|delta/epsilon subdivisions,2X9GK@28221|Deltaproteobacteria,43W2H@69541|Desulfuromonadales 28221|Deltaproteobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR SYD1_k127_3699653_10 1265505.ATUG01000003_gene25 2.406e-182 593.0 COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2MHX8@213118|Desulfobacterales 28221|Deltaproteobacteria P Voltage gated chloride channel - - - ko:K03281 - - - - ko00000 2.A.49 - - CBS,TrkA_C,Voltage_CLC SYD1_k127_3699653_84 1449069.JMLO01000003_gene3932 2.147e-63 226.0 COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria,4G0WP@85025|Nocardiaceae 201174|Actinobacteria F Glutamine amidotransferase class-I - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,Methyltransf_11 SYD1_k127_3699653_81 861299.J421_3663 1.633e-67 254.0 COG1228@1|root,COG1228@2|Bacteria,1ZSU7@142182|Gemmatimonadetes 142182|Gemmatimonadetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 SYD1_k127_3699653_103 1128421.JAGA01000002_gene1413 5.537e-44 171.0 COG1475@1|root,COG1475@2|Bacteria 2|Bacteria K chromosome segregation - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - N6_N4_Mtase,ParBc SYD1_k127_3699653_70 595460.RRSWK_00985 2.733e-75 264.0 COG1796@1|root,COG1796@2|Bacteria 2|Bacteria L DNA-directed DNA polymerase activity dpbF - 3.1.11.5 ko:K02347,ko:K03581,ko:K04477 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,HHH_8 SYD1_k127_3699653_19 448385.sce2596 6.639e-154 504.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,42YQ0@68525|delta/epsilon subdivisions,2WTRV@28221|Deltaproteobacteria,2YUFX@29|Myxococcales 28221|Deltaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - - SYD1_k127_3699653_74 240015.ACP_1336 2.724e-71 252.0 COG0506@1|root,COG0506@2|Bacteria,3Y2G8@57723|Acidobacteria,2JHRI@204432|Acidobacteriia 204432|Acidobacteriia E Proline dehydrogenase - - - ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R10507 RC00083 ko00000,ko00001,ko01000 - - - Pro_dh SYD1_k127_3699653_134 287986.DV20_28585 1.906e-22 106.0 COG1011@1|root,COG1011@2|Bacteria,2IBB1@201174|Actinobacteria,4E7YD@85010|Pseudonocardiales 201174|Actinobacteria S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 SYD1_k127_3699653_104 1279009.ADICEAN_02760 1.68e-43 164.0 COG2318@1|root,COG2318@2|Bacteria,4NRAP@976|Bacteroidetes,47NZT@768503|Cytophagia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 SYD1_k127_3699653_122 926560.KE387027_gene533 3.634e-29 127.0 COG2062@1|root,COG2062@2|Bacteria,1WN47@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T phosphohistidine phosphatase, SixA - - - - - - - - - - - - - SYD1_k127_3699653_92 1379698.RBG1_1C00001G0796 6.277e-51 186.0 COG1956@1|root,COG1956@2|Bacteria 2|Bacteria T GAF domain-containing protein yebR - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF,GAF_2 SYD1_k127_3699653_50 1379698.RBG1_1C00001G0797 1.308e-109 388.0 COG4191@1|root,COG4191@2|Bacteria,2NS4C@2323|unclassified Bacteria 2|Bacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_9,Response_reg SYD1_k127_3699653_114 1267535.KB906767_gene2392 8.978e-34 136.0 COG1846@1|root,COG1846@2|Bacteria,3Y861@57723|Acidobacteria 57723|Acidobacteria K Winged helix DNA-binding domain - - - - - - - - - - - - HTH_34 SYD1_k127_3699653_98 1128421.JAGA01000001_gene2144 4.749e-49 188.0 COG3127@1|root,COG3127@2|Bacteria 2|Bacteria Q FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SYD1_k127_3699653_63 765420.OSCT_1801 5.168e-87 305.0 COG2379@1|root,COG2379@2|Bacteria,2G5RZ@200795|Chloroflexi,374XG@32061|Chloroflexia 32061|Chloroflexia C PFAM MOFRL domain protein - - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL SYD1_k127_3699653_90 330214.NIDE4204 2.452e-52 195.0 COG3769@1|root,COG3769@2|Bacteria 2|Bacteria S mannosylglycerate metabolic process mpgP GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 ko:K05947,ko:K07026 ko00051,map00051 - R05768,R05790 RC00005,RC00017,RC00397,RC02748 ko00000,ko00001,ko01000,ko01003 - - - Hydrolase_3 SYD1_k127_3699653_24 330214.NIDE1666 9.383e-141 457.0 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups gpgS - 2.4.1.266 ko:K13693 - - - - ko00000,ko01000,ko01003 - GT81 - - SYD1_k127_3699653_130 671143.DAMO_1538 5.013e-24 119.0 COG0668@1|root,COG0668@2|Bacteria,2NQ6B@2323|unclassified Bacteria 2|Bacteria M transmembrane transport cmpX - - - - - - - - - - - MS_channel,TM_helix SYD1_k127_3699653_23 330214.NIDE4207 2.78e-146 492.0 COG0463@1|root,COG0463@2|Bacteria 2|Bacteria M Glycosyl transferase, family 2 - - 2.4.1.268 ko:K21349 - - - - ko00000,ko01000 - GT81 - Glycos_transf_2 SYD1_k127_3699653_64 1121028.ARQE01000009_gene4051 8.147e-85 306.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Belongs to the ABC transporter superfamily ugpC - 3.6.3.20 ko:K05816 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1.3 - - ABC_tran,TOBE_2 SYD1_k127_3699653_83 1487953.JMKF01000071_gene3385 4.643e-66 247.0 COG0395@1|root,COG0395@2|Bacteria,1G0CF@1117|Cyanobacteria,1H6X9@1150|Oscillatoriales 1117|Cyanobacteria G PFAM Binding-protein-dependent transport system inner membrane component ugpE - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 SYD1_k127_3699653_67 272134.KB731324_gene3720 8.636e-78 287.0 COG1175@1|root,COG1175@2|Bacteria,1G0YN@1117|Cyanobacteria,1H7ZN@1150|Oscillatoriales 1117|Cyanobacteria P PFAM Binding-protein-dependent transport system inner membrane component ugpA - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 SYD1_k127_3699653_48 306281.AJLK01000066_gene5468 1.328e-111 391.0 COG1653@1|root,COG1653@2|Bacteria,1G0AA@1117|Cyanobacteria,1JJ8D@1189|Stigonemataceae 1117|Cyanobacteria G Bacterial extracellular solute-binding protein ugpB - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1 SYD1_k127_3699653_72 1169161.KB897725_gene1813 3.119e-73 276.0 COG0668@1|root,COG0668@2|Bacteria,2GZI1@201174|Actinobacteria 201174|Actinobacteria M mechanosensitive ion channel - - - - - - - - - - - - MS_channel,cNMP_binding SYD1_k127_3699653_3 1142394.PSMK_25030 4.735e-252 810.0 COG0348@1|root,COG0492@1|root,COG0348@2|Bacteria,COG0492@2|Bacteria,2J1NR@203682|Planctomycetes 203682|Planctomycetes C 4Fe-4S binding domain - - - - - - - - - - - - Fer4_5 SYD1_k127_3699653_133 1394178.AWOO02000009_gene4242 1.747e-22 115.0 COG0500@1|root,COG2226@2|Bacteria,2I5FG@201174|Actinobacteria 201174|Actinobacteria Q Methionine biosynthesis protein MetW - - - - - - - - - - - - - SYD1_k127_3699653_73 404589.Anae109_1011 2.142e-71 250.0 COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,42KZF@68525|delta/epsilon subdivisions,2WSRV@28221|Deltaproteobacteria 28221|Deltaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE SYD1_k127_3699653_111 1211115.ALIQ01000220_gene1435 2.665e-35 151.0 COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,2U6ME@28211|Alphaproteobacteria,3NB8J@45404|Beijerinckiaceae 28211|Alphaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C SYD1_k127_3699653_158 188626.HMPREF0321_1812 3.827e-07 60.0 COG2318@1|root,COG2318@2|Bacteria,2HUJD@201174|Actinobacteria,1ZWYV@145357|Dermacoccaceae 201174|Actinobacteria S DinB superfamily - - - - - - - - - - - - DUF664 SYD1_k127_3699653_65 313624.NSP_14580 5.418e-83 296.0 COG0277@1|root,COG0277@2|Bacteria,1G6C2@1117|Cyanobacteria,1HIC7@1161|Nostocales 1117|Cyanobacteria C FAD binding domain - - 1.1.3.8,1.5.99.12 ko:K00103,ko:K00279 ko00053,ko00908,ko01100,map00053,map00908,map01100 M00129 R00647,R03184,R05708,R10053 RC00121,RC00195,RC00346,RC00869,RC01455 ko00000,ko00001,ko00002,ko01000 - - - ALO,Cytokin-bind,FAD_binding_4 SYD1_k127_3699653_150 348780.NP_1376A 6.526e-11 69.0 COG3255@1|root,arCOG01842@2157|Archaea,2XXJM@28890|Euryarchaeota,23X5Y@183963|Halobacteria 183963|Halobacteria I sterol carrier protein - - - - - - - - - - - - SCP2 SYD1_k127_3699653_102 1242864.D187_004642 9.571e-46 177.0 COG0454@1|root,COG0456@2|Bacteria,1Q1ZZ@1224|Proteobacteria,42USA@68525|delta/epsilon subdivisions,2WQ2Q@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 SYD1_k127_3699653_159 1463857.JOFZ01000007_gene252 1.231e-06 61.0 COG3170@1|root,COG3170@2|Bacteria,2I40K@201174|Actinobacteria 201174|Actinobacteria NU Glycosyltransferase family 87 - - - ko:K13671 - - - - ko00000,ko01000,ko01003 - GT87 - GT87 SYD1_k127_3699653_129 1479237.JMLY01000001_gene2639 3.884e-25 114.0 COG0517@1|root,COG0517@2|Bacteria,1QTVM@1224|Proteobacteria,1SFWU@1236|Gammaproteobacteria,46BCN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS SYD1_k127_3699653_126 671143.DAMO_0987 4.918e-27 120.0 COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria 2|Bacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 SYD1_k127_3699653_96 485915.Dret_0201 2.566e-49 190.0 COG4191@1|root,COG4191@2|Bacteria,1R6WR@1224|Proteobacteria,42PFK@68525|delta/epsilon subdivisions,2WJSP@28221|Deltaproteobacteria,2M8KY@213115|Desulfovibrionales 28221|Deltaproteobacteria T PFAM ATP-binding region ATPase domain protein - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_9 SYD1_k127_3699653_41 246194.CHY_1855 4.623e-122 409.0 COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,42J66@68295|Thermoanaerobacterales 186801|Clostridia T PFAM sigma-54 factor interaction domain-containing protein - - - ko:K02481,ko:K07714 ko02020,map02020 M00500 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_3699653_66 861299.J421_4262 1.243e-82 284.0 COG0697@1|root,COG0697@2|Bacteria 2|Bacteria EG spore germination - - - - - - - - - - - - EamA SYD1_k127_3699653_91 1198114.AciX9_2489 1.298e-51 206.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity wcoG - - - - - - - - - - - DUF5122,Laminin_G_3,PKD SYD1_k127_3699653_156 518766.Rmar_1429 6.974e-08 66.0 COG3292@1|root,COG3292@2|Bacteria,4NI2T@976|Bacteroidetes 976|Bacteroidetes T Two component regulator propeller - - - - - - - - - - - - Reg_prop,YceI SYD1_k127_3699653_163 1333998.M2A_2521 0.000629 51.0 2BCV0@1|root,326FP@2|Bacteria,1MYXP@1224|Proteobacteria,2U5PU@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - ko:K20326 ko02024,map02024 - - - ko00000,ko00001 - - - Phenol_MetA_deg SYD1_k127_3699653_69 497964.CfE428DRAFT_3859 5.147e-76 273.0 COG0697@1|root,COG0697@2|Bacteria,46T3I@74201|Verrucomicrobia 74201|Verrucomicrobia EG EamA-like transporter family - - - - - - - - - - - - EamA SYD1_k127_3699653_95 886293.Sinac_2076 1.108e-49 194.0 COG1522@1|root,COG1522@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type SYD1_k127_3699653_110 1267535.KB906767_gene341 2.539e-37 157.0 28JRZ@1|root,2Z9HI@2|Bacteria,3Y7HD@57723|Acidobacteria 57723|Acidobacteria S Domain of unknown function (DUF4126) - - - - - - - - - - - - DUF4126 SYD1_k127_3699653_8 1382359.JIAL01000001_gene577 4.586e-209 666.0 COG1217@1|root,COG1217@2|Bacteria,3Y33Q@57723|Acidobacteria,2JIIC@204432|Acidobacteriia 204432|Acidobacteriia T GTP-binding protein TypA - - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 SYD1_k127_3699653_6 234267.Acid_6681 1.932e-211 666.0 COG1271@1|root,COG1271@2|Bacteria,3Y44V@57723|Acidobacteria 57723|Acidobacteria C Cytochrome bd terminal oxidase subunit I - - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I SYD1_k127_3699653_36 234267.Acid_6682 2.381e-129 423.0 COG1294@1|root,COG1294@2|Bacteria,3Y3UT@57723|Acidobacteria 57723|Acidobacteria C Cytochrome d ubiquinol oxidase, subunit II - - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II SYD1_k127_3699653_77 1340434.AXVA01000004_gene2785 1.186e-70 247.0 COG1028@1|root,COG1028@2|Bacteria,1TSCT@1239|Firmicutes,4HD4Z@91061|Bacilli,1ZD54@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 SYD1_k127_3699653_87 945713.IALB_0545 5.429e-57 209.0 COG0330@1|root,COG0330@2|Bacteria 2|Bacteria O stress-induced mitochondrial fusion - - - - - - - - - - - - Band_7 SYD1_k127_3699653_155 1123236.KB899386_gene1849 9.478e-09 66.0 COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,466GU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative adhesin - - - - - - - - - - - - DUF4097 SYD1_k127_3699653_148 379066.GAU_2724 6.657e-13 78.0 2F756@1|root,33ZKP@2|Bacteria,1ZU38@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - SYD1_k127_3699653_89 861299.J421_4375 1.07e-52 192.0 COG1595@1|root,COG1595@2|Bacteria,1ZTNR@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SYD1_k127_3699653_86 379066.GAU_2304 5.137e-62 229.0 COG3595@1|root,COG3595@2|Bacteria,1ZTJA@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Putative adhesin - - - - - - - - - - - - DUF4097 SYD1_k127_3699653_152 266779.Meso_3504 6.005e-10 64.0 COG3071@1|root,COG3071@2|Bacteria,1N6Y8@1224|Proteobacteria,2UFTD@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Protein of unknown function (DUF2905) - - - - - - - - - - - - DUF2905 SYD1_k127_3699653_35 452637.Oter_1656 4.222e-131 423.0 COG2013@1|root,COG2013@2|Bacteria,46SY6@74201|Verrucomicrobia 74201|Verrucomicrobia S Mitochondrial biogenesis AIM24 - - - - - - - - - - - - AIM24 SYD1_k127_3699653_144 452637.Oter_2236 5.077e-14 73.0 COG4877@1|root,COG4877@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Arc,RHH_5 SYD1_k127_3699653_57 319795.Dgeo_2423 4.301e-95 320.0 COG0330@1|root,COG0330@2|Bacteria,1WIW0@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O PFAM SPFH domain Band 7 family - - - - - - - - - - - - Band_7 SYD1_k127_3699653_2 575540.Isop_2142 1.33e-254 797.0 COG0488@1|root,COG0488@2|Bacteria,2IWXR@203682|Planctomycetes 203682|Planctomycetes S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn SYD1_k127_3699653_135 234267.Acid_5312 1.884e-21 98.0 COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria 57723|Acidobacteria S PFAM Iron sulphur-containing domain, CDGSH-type - - - - - - - - - - - - zf-CDGSH SYD1_k127_3699653_78 42256.RradSPS_3058 1.264e-70 255.0 COG1503@1|root,COG1503@2|Bacteria 2|Bacteria J translation release factor activity - - - - - - - - - - - - - SYD1_k127_3699653_15 927658.AJUM01000034_gene68 5.453e-171 561.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,2FN1K@200643|Bacteroidia,3XJPB@558415|Marinilabiliaceae 976|Bacteroidetes EU Prolyl oligopeptidase family - - - - - - - - - - - - PD40,Peptidase_S9 SYD1_k127_3699653_140 1198114.AciX9_0974 2.379e-18 94.0 COG2823@1|root,COG2823@2|Bacteria,3Y3MJ@57723|Acidobacteria,2JIN1@204432|Acidobacteriia 204432|Acidobacteriia S BON domain - - - - - - - - - - - - BON SYD1_k127_3699653_49 671143.DAMO_0966 1.331e-110 369.0 COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2NPE1@2323|unclassified Bacteria 2|Bacteria S Peptidase family M50 spoIVFB GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K06212,ko:K06402 - - - - ko00000,ko01000,ko01002,ko02000 1.A.16.1.1,1.A.16.1.3 - - CBS,Form_Nir_trans,Peptidase_M50 SYD1_k127_3699653_118 404589.Anae109_2452 2.832e-31 143.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase A domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,RsbRD_N,SBP_bac_3 SYD1_k127_3699653_4 1382306.JNIM01000001_gene2570 2.94e-237 743.0 COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi 200795|Chloroflexi I PFAM carboxyl transferase - - 2.1.3.15,6.4.1.3,6.4.1.4 ko:K01969,ko:K15052 ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200 M00036,M00376 R01859,R04138 RC00097,RC00367,RC00609,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans SYD1_k127_3699653_75 1128421.JAGA01000002_gene1141 8.879e-71 249.0 COG1024@1|root,COG1024@2|Bacteria,2NR3A@2323|unclassified Bacteria 2|Bacteria I Enoyl-CoA hydratase/isomerase atuE - 4.2.1.18,4.2.1.57 ko:K13766,ko:K13779 ko00280,ko00281,ko01100,map00280,map00281,map01100 M00036 R02085,R03493 RC00941,RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 SYD1_k127_3699653_37 502025.Hoch_1857 8.102e-128 437.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,43BQE@68525|delta/epsilon subdivisions,2X71H@28221|Deltaproteobacteria,2YX6T@29|Myxococcales 28221|Deltaproteobacteria I Biotin carboxylase C-terminal domain - - 6.4.1.4,6.4.1.5 ko:K01968,ko:K13777 ko00280,ko00281,ko01100,map00280,map00281,map01100 M00036 R03494,R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 SYD1_k127_3699653_145 1317118.ATO8_16028 5.886e-14 86.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,4KKNE@93682|Roseivivax 28211|Alphaproteobacteria I 3-methylcrotonyl-CoA carboxylase subunit alpha mccA - 6.4.1.4 ko:K01968 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 SYD1_k127_3699653_55 1121405.dsmv_1899 2.209e-97 344.0 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,42Q6T@68525|delta/epsilon subdivisions,2WIN1@28221|Deltaproteobacteria,2MIW0@213118|Desulfobacterales 28221|Deltaproteobacteria E PFAM pyruvate carboxyltransferase mvaB - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like SYD1_k127_3699653_61 1379698.RBG1_1C00001G0675 9.146e-90 330.0 COG1748@1|root,COG1748@2|Bacteria,2NPF8@2323|unclassified Bacteria 2|Bacteria E Saccharopine dehydrogenase C-terminal domain lysDH - 1.4.1.18 ko:K19064 ko00960,ko01100,ko01110,map00960,map01100,map01110 - R00446,R02317 RC00062,RC00694 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP SYD1_k127_3699653_43 1123242.JH636435_gene2052 7.881e-120 400.0 COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes 203682|Planctomycetes P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger SYD1_k127_3699653_154 909943.HIMB100_00004610 8.654e-09 65.0 COG4785@1|root,COG4785@2|Bacteria,1R0JJ@1224|Proteobacteria,2TYRH@28211|Alphaproteobacteria,4BTFI@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_2 SYD1_k127_3699653_52 234267.Acid_1081 8.203e-101 336.0 COG2326@1|root,COG2326@2|Bacteria,3Y44F@57723|Acidobacteria 57723|Acidobacteria S Polyphosphate kinase 2 (PPK2) - - - - - - - - - - - - PPK2 SYD1_k127_3703984_43 926560.KE387023_gene2058 1.643e-22 100.0 COG2020@1|root,COG2020@2|Bacteria 2|Bacteria O methyltransferase activity - - - - - - - - - - - - PEMT SYD1_k127_3703984_49 882082.SaccyDRAFT_4155 7.097e-19 96.0 2E35R@1|root,32Y5N@2|Bacteria,2H8P1@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - SYD1_k127_3703984_24 298654.FraEuI1c_6373 6.849e-49 178.0 COG0662@1|root,COG0662@2|Bacteria,2IMHT@201174|Actinobacteria 201174|Actinobacteria G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2,EutQ SYD1_k127_3703984_21 344747.PM8797T_14489 3.926e-63 222.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Acetyltransf_3 SYD1_k127_3703984_31 663610.JQKO01000016_gene1584 5.087e-36 145.0 COG1309@1|root,COG1309@2|Bacteria,1N6WG@1224|Proteobacteria,2UG93@28211|Alphaproteobacteria,3NCQD@45404|Beijerinckiaceae 28211|Alphaproteobacteria K PFAM regulatory protein TetR - - - ko:K16137 - - - - ko00000,ko03000 - - - TetR_C_13,TetR_N SYD1_k127_3703984_15 1173263.Syn7502_03323 2.786e-74 262.0 COG4221@1|root,COG4221@2|Bacteria,1G3IS@1117|Cyanobacteria,1H369@1129|Synechococcus 1117|Cyanobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short SYD1_k127_3703984_29 290397.Adeh_1007 4.468e-40 152.0 COG3795@1|root,COG3795@2|Bacteria,1RH6U@1224|Proteobacteria 1224|Proteobacteria S YCII-related domain - - - - - - - - - - - - YCII SYD1_k127_3703984_16 595537.Varpa_5255 6.332e-74 254.0 COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,2VR7G@28216|Betaproteobacteria,4ADZG@80864|Comamonadaceae 28216|Betaproteobacteria S Activator of Hsp90 ATPase 1 family protein - - - - - - - - - - - - AHSA1 SYD1_k127_3703984_51 1206720.BAFQ01000042_gene1067 7.15e-13 76.0 2EJQK@1|root,33DFE@2|Bacteria,2IND9@201174|Actinobacteria,4G291@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - SYD1_k127_3703984_9 666685.R2APBS1_0246 5.979e-107 349.0 COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,1S2TQ@1236|Gammaproteobacteria,1X4M1@135614|Xanthomonadales 135614|Xanthomonadales H RibD C-terminal domain - - - - - - - - - - - - RibD_C SYD1_k127_3703984_48 452637.Oter_3057 2.405e-19 92.0 2DPXD@1|root,333T1@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 SYD1_k127_3703984_47 479432.Sros_4960 4.518e-20 98.0 COG1249@1|root,COG1249@2|Bacteria,2I5DW@201174|Actinobacteria 201174|Actinobacteria C Alkylmercury lyase - - - - - - - - - - - - MerB SYD1_k127_3703984_52 749927.AMED_2325 3.306e-07 54.0 2AAWD@1|root,3109H@2|Bacteria,2IG0D@201174|Actinobacteria,4E8XP@85010|Pseudonocardiales 201174|Actinobacteria S Alkylmercury lyase - - - - - - - - - - - - MerB SYD1_k127_3703984_50 1131553.JIBI01000080_gene2368 9.724e-17 90.0 2DQ2S@1|root,334IA@2|Bacteria,1NAEM@1224|Proteobacteria,2WBK2@28216|Betaproteobacteria,373AW@32003|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - SYD1_k127_3703984_37 324925.Ppha_0987 2.517e-31 130.0 COG2318@1|root,COG2318@2|Bacteria,1FF75@1090|Chlorobi 1090|Chlorobi S DinB family - - - - - - - - - - - - DinB SYD1_k127_3703984_7 296591.Bpro_1676 3.804e-116 390.0 COG0500@1|root,COG2226@2|Bacteria,1R79J@1224|Proteobacteria 1224|Proteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 SYD1_k127_3703984_10 794903.OPIT5_00730 7.322e-100 341.0 COG4529@1|root,COG4529@2|Bacteria,46Y2C@74201|Verrucomicrobia,3K8TZ@414999|Opitutae 414999|Opitutae S FAD-NAD(P)-binding - - - - - - - - - - - - NAD_binding_9 SYD1_k127_3703984_3 2002.JOEQ01000003_gene2490 1.114e-132 430.0 COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4EI60@85012|Streptosporangiales 201174|Actinobacteria EK Pyridoxal-phosphate dependent enzyme - - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP SYD1_k127_3703984_20 452637.Oter_4300 3.508e-63 218.0 COG3189@1|root,COG3189@2|Bacteria,46WUI@74201|Verrucomicrobia,3K8H8@414999|Opitutae 414999|Opitutae S Protein of unknown function, DUF488 - - - - - - - - - - - - DUF488 SYD1_k127_3703984_5 1123508.JH636440_gene2923 2.18e-123 402.0 COG0388@1|root,COG0388@2|Bacteria,2J2IE@203682|Planctomycetes 203682|Planctomycetes S Carbon-nitrogen hydrolase - - - - - - - - - - - - CN_hydrolase SYD1_k127_3703984_40 1197906.CAJQ02000047_gene4077 7.582e-28 126.0 COG2329@1|root,COG2329@2|Bacteria,1N2ZS@1224|Proteobacteria,2UEPY@28211|Alphaproteobacteria,3K08M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - - SYD1_k127_3703984_30 926560.KE387025_gene4075 5.408e-39 156.0 2B5RU@1|root,31YMF@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Hemerythrin SYD1_k127_3703984_36 335543.Sfum_2937 4.488e-33 138.0 COG3945@1|root,COG3945@2|Bacteria,1RG8J@1224|Proteobacteria,42S6P@68525|delta/epsilon subdivisions,2WNYW@28221|Deltaproteobacteria,2MS0X@213462|Syntrophobacterales 28221|Deltaproteobacteria S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin SYD1_k127_3703984_53 452637.Oter_0555 4.859e-05 54.0 2DGM2@1|root,2ZWFW@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_3703984_33 404589.Anae109_1576 5.569e-35 136.0 2FCGD@1|root,344JU@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_3703984_25 1396141.BATP01000018_gene1556 4.087e-48 186.0 COG1670@1|root,COG1670@2|Bacteria,46XI2@74201|Verrucomicrobia,2IVZ1@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 SYD1_k127_3703984_28 266835.14022327 1.481e-40 156.0 COG2020@1|root,COG2020@2|Bacteria,1MXP9@1224|Proteobacteria,2U2A4@28211|Alphaproteobacteria,43MDZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria O PFAM Isoprenylcysteine carboxyl methyltransferase - - - - - - - - - - - - ICMT,PEMT SYD1_k127_3703984_26 1463936.JOJI01000059_gene6084 1.253e-44 170.0 COG0346@1|root,COG0346@2|Bacteria,2GRGB@201174|Actinobacteria 201174|Actinobacteria E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase_3 SYD1_k127_3703984_18 1123234.AUKI01000019_gene552 4.964e-72 259.0 28KH6@1|root,2ZA2R@2|Bacteria,4NI7X@976|Bacteroidetes,1HYH8@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - SYD1_k127_3703984_12 765912.Thimo_0714 7.329e-83 280.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1S237@1236|Gammaproteobacteria,1WWYK@135613|Chromatiales 135613|Chromatiales P Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA SYD1_k127_3703984_11 709986.Deima_1229 4.844e-85 291.0 COG0667@1|root,COG0667@2|Bacteria 2|Bacteria C Aldo Keto reductase - - - - - - - - - - - - Aldo_ket_red SYD1_k127_3703984_2 262724.TT_C0897 1.98e-151 499.0 COG1640@1|root,COG1640@2|Bacteria,1WJDF@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G PFAM glycoside hydrolase, family 77 malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 SYD1_k127_3703984_0 330214.NIDE1289 1.465e-244 775.0 COG0058@1|root,COG0058@2|Bacteria,3J0W1@40117|Nitrospirae 40117|Nitrospirae G Carbohydrate phosphorylase - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DUF3417,Phosphorylase SYD1_k127_3703984_27 886293.Sinac_6240 8.325e-43 166.0 COG0861@1|root,COG0861@2|Bacteria,2J0FS@203682|Planctomycetes 203682|Planctomycetes P PFAM Integral membrane protein TerC - - - - - - - - - - - - TerC SYD1_k127_3703984_6 945713.IALB_2989 9.077e-117 414.0 COG0616@1|root,COG0616@2|Bacteria 2|Bacteria OU serine-type peptidase activity sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 SYD1_k127_3703984_23 1382359.JIAL01000001_gene1199 2.585e-55 218.0 COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia 204432|Acidobacteriia KT Sigma factor PP2C-like phosphatases - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - GAF_3,SpoIIE SYD1_k127_3703984_46 1121957.ATVL01000011_gene3666 8.116e-21 97.0 COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,47QUX@768503|Cytophagia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase rsbW - 2.7.11.1 ko:K04757 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c_2 SYD1_k127_3703984_22 477974.Daud_0538 8.897e-60 222.0 COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,267DC@186807|Peptococcaceae 186801|Clostridia T Metal-dependent phosphohydrolase, HD region - - - - - - - - - - - - GAF_2,GGDEF,HD,PAS,PocR,SBP_bac_3 SYD1_k127_3703984_17 269799.Gmet_2451 4.186e-73 254.0 COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,42Q7J@68525|delta/epsilon subdivisions,2WJCK@28221|Deltaproteobacteria,43T44@69541|Desulfuromonadales 28221|Deltaproteobacteria O PFAM cytochrome c biogenesis protein, transmembrane region ccdA - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD,Thioredoxin SYD1_k127_3703984_32 204669.Acid345_0181 1.236e-35 144.0 COG0526@1|root,COG0526@2|Bacteria,3Y4K8@57723|Acidobacteria,2JJAP@204432|Acidobacteriia 204432|Acidobacteriia CO Glutathione peroxidase - - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA SYD1_k127_3703984_1 1379281.AVAG01000001_gene249 2.549e-186 592.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2M8XA@213115|Desulfovibrionales 28221|Deltaproteobacteria E PFAM glutamine synthetase catalytic region glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N SYD1_k127_3703984_38 1379698.RBG1_1C00001G0814 4.792e-29 123.0 COG0454@1|root,COG0456@2|Bacteria,2NRWK@2323|unclassified Bacteria 2|Bacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 SYD1_k127_3703984_19 575540.Isop_3700 3.611e-69 239.0 COG0432@1|root,COG0432@2|Bacteria,2IZ7Q@203682|Planctomycetes 203682|Planctomycetes S PFAM Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 SYD1_k127_3703984_45 404589.Anae109_0362 6.705e-21 102.0 COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,42MF3@68525|delta/epsilon subdivisions,2WJXS@28221|Deltaproteobacteria,2YVQQ@29|Myxococcales 28221|Deltaproteobacteria G Class II Aldolase and Adducin N-terminal domain - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II SYD1_k127_3703984_8 1121468.AUBR01000010_gene2431 3e-113 385.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,42EWB@68295|Thermoanaerobacterales 186801|Clostridia H Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - ACPS,Carb_kinase,YjeF_N SYD1_k127_3703984_41 401053.AciPR4_0762 1.867e-27 115.0 COG0736@1|root,COG0736@2|Bacteria,3Y590@57723|Acidobacteria,2JJPD@204432|Acidobacteriia 204432|Acidobacteriia I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS SYD1_k127_3703984_35 195522.BD01_0631 2.97e-33 138.0 COG1011@1|root,arCOG02291@2157|Archaea,2XTX3@28890|Euryarchaeota,243KR@183968|Thermococci 183968|Thermococci S Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro - - - ko:K07025 - - - - ko00000 - - - HAD_2 SYD1_k127_3703984_39 861299.J421_3007 3.515e-28 115.0 2EQ8R@1|root,33HV0@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_3703984_13 204669.Acid345_1835 5.955e-79 280.0 COG1215@1|root,COG1215@2|Bacteria,3Y2GM@57723|Acidobacteria,2JI7F@204432|Acidobacteriia 204432|Acidobacteriia M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 SYD1_k127_3703984_4 1128421.JAGA01000002_gene62 4.629e-126 411.0 COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria 2|Bacteria S Putative esterase - - - - - - - - - - - - Esterase SYD1_k127_3703984_44 861299.J421_3473 5.03e-22 104.0 COG0599@1|root,COG0599@2|Bacteria,1ZTPF@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Carboxymuconolactone decarboxylase family - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD SYD1_k127_3703984_42 1162668.LFE_0244 2.659e-26 114.0 COG0253@1|root,COG0253@2|Bacteria,3J0JV@40117|Nitrospirae 40117|Nitrospirae E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase SYD1_k127_374673_0 1349767.GJA_2643 3.217e-273 855.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria,473C1@75682|Oxalobacteraceae 28216|Betaproteobacteria E - Amino acid transport and metabolism asnB1 - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 SYD1_k127_374673_6 472759.Nhal_3309 1.516e-95 332.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RPQF@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyltransferase Family 4 - - 2.4.1.346 ko:K13668 - - R11703,R11704 - ko00000,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 SYD1_k127_374673_12 702113.PP1Y_AT8041 1.222e-78 274.0 COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2TTTU@28211|Alphaproteobacteria,2K23Q@204457|Sphingomonadales 204457|Sphingomonadales M NAD-dependent epimerase dehydratase - - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase SYD1_k127_374673_3 479432.Sros_6500 3.486e-142 474.0 COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4EI6C@85012|Streptosporangiales 201174|Actinobacteria E Asparagine synthase - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 SYD1_k127_374673_26 1469613.JT55_13220 3.946e-13 81.0 COG0392@1|root,COG0392@2|Bacteria 2|Bacteria M lysyltransferase activity - - - - - - - - - - - - LPG_synthase_TM SYD1_k127_374673_10 472759.Nhal_3295 8.793e-82 301.0 COG1680@1|root,COG1680@2|Bacteria,1NPBV@1224|Proteobacteria,1SQWZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Domain of unknown function (DUF4185) - - - - - - - - - - - - DUF4185 SYD1_k127_374673_11 472759.Nhal_3295 6.193e-80 290.0 COG1680@1|root,COG1680@2|Bacteria,1NPBV@1224|Proteobacteria,1SQWZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Domain of unknown function (DUF4185) - - - - - - - - - - - - DUF4185 SYD1_k127_374673_18 525904.Tter_1175 7.955e-33 145.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase yxbB - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 SYD1_k127_374673_17 797302.Halru_2513 5.417e-35 153.0 COG2244@1|root,arCOG02209@2157|Archaea,2XVVS@28890|Euryarchaeota,23UCY@183963|Halobacteria 183963|Halobacteria S Membrane protein involved in the export of O-antigen and teichoic acid - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C SYD1_k127_374673_20 635013.TherJR_2843 1.004e-30 140.0 COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,1UASH@1239|Firmicutes,248VW@186801|Clostridia,262C0@186807|Peptococcaceae 186801|Clostridia M PFAM Glycosyl - - 2.4.1.349 ko:K12994 - - - - ko00000,ko01000,ko01003,ko01005 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 SYD1_k127_374673_16 313612.L8106_08576 7.989e-39 160.0 COG0726@1|root,COG0726@2|Bacteria 2|Bacteria G polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 SYD1_k127_374673_13 472759.Nhal_3295 8.016e-73 261.0 COG1680@1|root,COG1680@2|Bacteria,1NPBV@1224|Proteobacteria,1SQWZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Domain of unknown function (DUF4185) - - - - - - - - - - - - DUF4185 SYD1_k127_374673_21 472759.Nhal_3308 4.073e-24 119.0 COG1988@1|root,COG1988@2|Bacteria 2|Bacteria NT membrane-bound metal-dependent ybcI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07038 - - - - ko00000 - - - YdjM SYD1_k127_374673_4 1195246.AGRI_00715 4.755e-126 426.0 COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria,469ZI@72275|Alteromonadaceae 1236|Gammaproteobacteria O carbamoyl transferase, NodU family - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N SYD1_k127_374673_27 1123277.KB893228_gene2124 6.533e-05 56.0 COG0500@1|root,COG0500@2|Bacteria,4PN9N@976|Bacteroidetes,47N70@768503|Cytophagia 976|Bacteroidetes Q CheR methyltransferase, SAM binding domain - - - - - - - - - - - - Methyltransf_23,Methyltransf_25 SYD1_k127_374673_1 472759.Nhal_3311 2.216e-186 598.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1X0QS@135613|Chromatiales 135613|Chromatiales C PFAM FAD dependent oxidoreductase - - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C SYD1_k127_374673_15 1254432.SCE1572_42895 6.638e-48 194.0 COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42MCE@68525|delta/epsilon subdivisions,2WIYP@28221|Deltaproteobacteria,2YYXE@29|Myxococcales 28221|Deltaproteobacteria M Glycosyltransferase like family 2 - - 2.4.2.53 ko:K10012 ko00520,ko01503,map00520,map01503 M00721,M00761 R07661 RC00005,RC02954 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 4.D.2.1.8 GT2 - Glycos_transf_2 SYD1_k127_374673_8 1122180.Lokhon_00112 2.972e-91 310.0 COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2U5W4@28211|Alphaproteobacteria 28211|Alphaproteobacteria M glycosyl transferase - GO:0000271,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0030258,GO:0030259,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - - - - - - - - - - Glycos_transf_2 SYD1_k127_374673_9 519989.ECTPHS_06382 1.121e-89 328.0 COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,1T22W@1236|Gammaproteobacteria,1X2NU@135613|Chromatiales 135613|Chromatiales V TIGRFAM FemAB-related protein, PEP-CTERM system-associated - - - - - - - - - - - - Acetyltransf_6 SYD1_k127_374673_7 383372.Rcas_3084 2.066e-93 316.0 COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia 32061|Chloroflexia M short-chain dehydrogenase reductase SDR - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase SYD1_k127_374673_2 1267535.KB906767_gene4059 5.11e-168 551.0 COG0677@1|root,COG0677@2|Bacteria,3Y30B@57723|Acidobacteria,2JIIN@204432|Acidobacteriia 204432|Acidobacteriia M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.136 ko:K13015 ko00520,map00520 - R00421 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N SYD1_k127_374673_19 1123242.JH636435_gene1448 2.09e-31 133.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2J0AY@203682|Planctomycetes 203682|Planctomycetes D Capsular exopolysaccharide family - - - - - - - - - - - - AAA_31,Wzz SYD1_k127_374673_25 857087.Metme_2601 5.797e-14 86.0 COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,1RXY8@1236|Gammaproteobacteria,1XG1V@135618|Methylococcales 135618|Methylococcales M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - - SYD1_k127_374673_22 1117319.PSPO_14087 2.869e-17 93.0 COG1596@1|root,COG1596@2|Bacteria,1PK0J@1224|Proteobacteria,1RM8V@1236|Gammaproteobacteria,2Q1XQ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M Polysaccharide biosynthesis/export protein - - - ko:K20987 ko02025,map02025 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB SYD1_k127_374673_5 338966.Ppro_2450 1.969e-119 406.0 COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,42MSY@68525|delta/epsilon subdivisions,2WJXR@28221|Deltaproteobacteria,43S9C@69541|Desulfuromonadales 28221|Deltaproteobacteria M Belongs to the UDP-N-acetylglucosamine 2-epimerase family wecB - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 SYD1_k127_374673_24 266117.Rxyl_3203 3.064e-14 85.0 COG1836@1|root,COG1836@2|Bacteria 2|Bacteria I PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - - - - - - - - - - DUF92 SYD1_k127_374673_23 1234679.BN424_734 5.729e-15 83.0 COG0170@1|root,COG1836@1|root,COG0170@2|Bacteria,COG1836@2|Bacteria,1V0YC@1239|Firmicutes,4HHFY@91061|Bacilli 91061|Bacilli I membrane - - - - - - - - - - - - DUF92 SYD1_k127_374673_14 215803.DB30_6730 1.865e-52 200.0 COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42Q7A@68525|delta/epsilon subdivisions,2WM81@28221|Deltaproteobacteria,2YW8C@29|Myxococcales 28221|Deltaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GAF,GGDEF SYD1_k127_3751045_39 234267.Acid_3938 3.868e-46 171.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria 2|Bacteria U Involved in the tonB-independent uptake of proteins - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase,WD40 SYD1_k127_3751045_66 1121861.KB899920_gene2926 2.794e-07 62.0 COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2UHNB@28211|Alphaproteobacteria,2JUGI@204441|Rhodospirillales 204441|Rhodospirillales M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C SYD1_k127_3751045_32 240015.ACP_1209 7.5e-61 217.0 COG4232@1|root,COG4232@2|Bacteria 2|Bacteria CO protein-disulfide reductase activity dsbD - 1.8.1.8 ko:K04084,ko:K06196 - - - - ko00000,ko01000,ko02000,ko03110 5.A.1.1,5.A.1.2 - - DsbD,DsbD_2 SYD1_k127_3751045_19 159087.Daro_2280 3.326e-116 391.0 COG4063@1|root,COG4063@2|Bacteria 2|Bacteria H Domain of unknown function (DUF4346) - - 2.1.1.86 ko:K00577 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00357,M00567 R04347 RC00035,RC00113,RC02892 ko00000,ko00001,ko00002,ko01000 - - - DUF4346,MtrA SYD1_k127_3751045_50 1541065.JRFE01000007_gene5145 3.844e-32 129.0 COG0640@1|root,COG0640@2|Bacteria,1G741@1117|Cyanobacteria,3VJRR@52604|Pleurocapsales 1117|Cyanobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_5 SYD1_k127_3751045_41 1242864.D187_002633 9.893e-42 159.0 COG2944@1|root,COG2944@2|Bacteria,1Q6DX@1224|Proteobacteria,432Z1@68525|delta/epsilon subdivisions,2WXF7@28221|Deltaproteobacteria 28221|Deltaproteobacteria K sequence-specific DNA binding - - - - - - - - - - - - MqsA_antitoxin SYD1_k127_3751045_2 1234364.AMSF01000079_gene1834 3.412e-266 839.0 COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,1RNY4@1236|Gammaproteobacteria,1X697@135614|Xanthomonadales 135614|Xanthomonadales P Alkaline phosphatase phoD2 - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N,TAT_signal SYD1_k127_3751045_16 404589.Anae109_1549 1.316e-125 431.0 COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,1MV1P@1224|Proteobacteria,42PPB@68525|delta/epsilon subdivisions,2X5YN@28221|Deltaproteobacteria,2YUEJ@29|Myxococcales 28221|Deltaproteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_10,TPR_12 SYD1_k127_3751045_70 1303692.SFUL_4367 3.635e-06 58.0 COG1075@1|root,COG1075@2|Bacteria,2GN6J@201174|Actinobacteria 201174|Actinobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - DUF676 SYD1_k127_3751045_67 459349.CLOAM1790 2.846e-07 64.0 COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria 2|Bacteria K Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS SYD1_k127_3751045_31 740709.A10D4_00975 3.166e-61 239.0 COG1520@1|root,COG3209@1|root,COG3210@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria 2|Bacteria U domain, Protein yeeJ - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - CHU_C,Calx-beta,Flg_new,HYR,Laminin_G_3,PQQ_2 SYD1_k127_3751045_38 1121288.AULL01000012_gene620 7.035e-48 197.0 COG1073@1|root,COG1073@2|Bacteria,4PMNT@976|Bacteroidetes,1IKPN@117743|Flavobacteriia 976|Bacteroidetes O Belongs to the peptidase S8 family - - - - - - - - - - - - DUF676,PGAP1 SYD1_k127_3751045_1 1037409.BJ6T_23810 3.323e-270 846.0 COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,3JSHP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Berberine and berberine like - - - - - - - - - - - - BBE,FAD_binding_4 SYD1_k127_3751045_14 1037409.BJ6T_23800 1.013e-130 419.0 COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,2U0MC@28211|Alphaproteobacteria,3JTRU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR,SCP2 SYD1_k127_3751045_24 187272.Mlg_2775 1.988e-93 325.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1WXWQ@135613|Chromatiales 135613|Chromatiales L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH SYD1_k127_3751045_11 103733.JNYO01000019_gene2036 3.873e-150 482.0 2C1EG@1|root,2Z7MZ@2|Bacteria,2GK4W@201174|Actinobacteria,4DZP1@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - - SYD1_k127_3751045_22 1282356.H045_18535 1.336e-98 340.0 COG4452@1|root,COG4452@2|Bacteria,1MVVR@1224|Proteobacteria,1RQRZ@1236|Gammaproteobacteria,1YMC2@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria V Inner membrane protein CreD creD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06143 - - - - ko00000 - - - CreD SYD1_k127_3751045_55 485913.Krac_5566 1.488e-26 115.0 COG4319@1|root,COG4319@2|Bacteria 2|Bacteria - - - - 5.3.3.1 ko:K01822 ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120 M00107,M00110 R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955 RC00146,RC00762 ko00000,ko00001,ko00002,ko01000 - - - DUF2358,DUF4440,SnoaL_2 SYD1_k127_3751045_25 1172180.KB911777_gene1804 2.24e-86 293.0 COG1247@1|root,COG1247@2|Bacteria,2II0A@201174|Actinobacteria 201174|Actinobacteria M -acetyltransferase - - - - - - - - - - - - - SYD1_k127_3751045_69 358220.C380_11350 1.627e-06 52.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VMNH@28216|Betaproteobacteria,4ABTU@80864|Comamonadaceae 28216|Betaproteobacteria BQ Histone deacetylase superfamily aphA1 - - - - - - - - - - - Hist_deacetyl SYD1_k127_3751045_15 234267.Acid_0873 1.259e-128 438.0 COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria 57723|Acidobacteria KLT Protein tyrosine kinase - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase SYD1_k127_3751045_20 926560.KE387023_gene2647 5.42e-116 382.0 COG0596@1|root,COG0596@2|Bacteria,1WN2Q@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L Transposase and inactivated derivatives - - - - - - - - - - - - - SYD1_k127_3751045_35 365046.Rta_36030 5.637e-56 202.0 COG0454@1|root,COG0454@2|Bacteria,1QUHE@1224|Proteobacteria,2VTMP@28216|Betaproteobacteria,4AJXX@80864|Comamonadaceae 28216|Betaproteobacteria K Acetyltransferase (GNAT) domain - - - ko:K03829 - - - - ko00000,ko01000 - - - Acetyltransf_1 SYD1_k127_3751045_0 211165.AJLN01000079_gene367 0.0 1262.0 COG3119@1|root,COG3119@2|Bacteria,1G3QV@1117|Cyanobacteria,1JJZ1@1189|Stigonemataceae 1117|Cyanobacteria P Sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase SYD1_k127_3751045_5 690850.Desaf_2574 2.678e-193 612.0 COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,42PD2@68525|delta/epsilon subdivisions,2WJIK@28221|Deltaproteobacteria,2M7WH@213115|Desulfovibrionales 28221|Deltaproteobacteria C PFAM Radical SAM - - - ko:K06871 - - - - ko00000 - - - Fer4_12,Radical_SAM,SEC-C,SPASM SYD1_k127_3751045_3 1071679.BG57_32360 2.866e-242 760.0 COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2VNDQ@28216|Betaproteobacteria,1K60X@119060|Burkholderiaceae 28216|Betaproteobacteria P Sulfatase - - 3.1.6.1,3.1.6.6 ko:K01130,ko:K01133 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C SYD1_k127_3751045_6 404589.Anae109_3731 4.591e-191 629.0 COG4775@1|root,COG4775@2|Bacteria 2|Bacteria M membrane organization - - - - - - - - - - - - Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA SYD1_k127_3751045_45 861299.J421_2099 5.2e-36 150.0 COG1285@1|root,COG1285@2|Bacteria,1ZUVP@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Domain of unknown function (DUF4956) - - - - - - - - - - - - DUF4956 SYD1_k127_3751045_40 290315.Clim_0819 6.154e-44 172.0 COG3204@1|root,COG3204@2|Bacteria,1FEUK@1090|Chlorobi 1090|Chlorobi S SdiA-regulated - - - - - - - - - - - - SdiA-regulated SYD1_k127_3751045_13 768671.ThimaDRAFT_4559 4.666e-134 447.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WXWA@135613|Chromatiales 135613|Chromatiales U sulphate transporter - - - - - - - - - - - - STAS,Sulfate_transp SYD1_k127_3751045_37 1449065.JMLL01000010_gene1581 1.313e-51 195.0 COG4291@1|root,COG4291@2|Bacteria,1RIAS@1224|Proteobacteria,2UHH1@28211|Alphaproteobacteria,43QAB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S membrane - - - - - - - - - - - - - SYD1_k127_3751045_54 251221.35212647 9.99e-27 115.0 2E3RZ@1|root,32YPK@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_3751045_63 765913.ThidrDRAFT_1295 6.898e-12 74.0 2ATWF@1|root,31JFP@2|Bacteria,1RK55@1224|Proteobacteria,1S6Q1@1236|Gammaproteobacteria,1WYHR@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - SYD1_k127_3751045_61 266834.SM_b20336 2.101e-17 96.0 COG2067@1|root,COG2067@2|Bacteria,1RJIQ@1224|Proteobacteria,2VGDP@28211|Alphaproteobacteria,4BA91@82115|Rhizobiaceae 28211|Alphaproteobacteria I long-chain fatty acid transport protein - - - - - - - - - - - - - SYD1_k127_3751045_62 159450.NH14_27675 5.382e-14 78.0 COG2149@1|root,COG2149@2|Bacteria,1N173@1224|Proteobacteria,2VYT4@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF202) - - - ko:K00389 - - - - ko00000 - - - DUF202 SYD1_k127_3751045_30 690850.Desaf_2584 1.095e-63 229.0 COG0385@1|root,COG0385@2|Bacteria,1Q36S@1224|Proteobacteria,42WV7@68525|delta/epsilon subdivisions,2WSXX@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM Bile acid sodium symporter - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF SYD1_k127_3751045_47 85643.Tmz1t_1462 5.593e-34 141.0 arCOG10317@1|root,2Z7VW@2|Bacteria,1RGUS@1224|Proteobacteria,2VYXP@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - SYD1_k127_3751045_53 85643.Tmz1t_1466 3.533e-27 115.0 COG4566@1|root,COG4566@2|Bacteria 2|Bacteria T phosphorelay signal transduction system - - - ko:K14987 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg SYD1_k127_3751045_34 85643.Tmz1t_3866 7.885e-58 213.0 COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,2VSM1@28216|Betaproteobacteria,2M008@206389|Rhodocyclales 1224|Proteobacteria K Two component transcriptional regulator, LuxR family - - - - - - - - - - - - GerE,Response_reg SYD1_k127_3751045_26 335543.Sfum_0942 2.827e-81 294.0 COG2202@1|root,COG3829@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WJKV@28221|Deltaproteobacteria 28221|Deltaproteobacteria T PFAM ATP-binding region, ATPase domain protein - - 2.7.13.3 ko:K02482,ko:K10819 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9 SYD1_k127_3751045_57 1267535.KB906767_gene996 9.487e-25 110.0 COG2318@1|root,COG2318@2|Bacteria,3Y5VC@57723|Acidobacteria,2JNRR@204432|Acidobacteriia 204432|Acidobacteriia S DinB superfamily - - - - - - - - - - - - DinB_2 SYD1_k127_3751045_58 926560.KE387027_gene964 1.008e-24 120.0 COG5516@1|root,COG5516@2|Bacteria,1WMR5@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Putative stress-induced transcription regulator - - - - - - - - - - - - ABATE,zf-CGNR SYD1_k127_3751045_21 530564.Psta_3105 3.409e-111 365.0 COG2321@1|root,COG2321@2|Bacteria,2IZ1Y@203682|Planctomycetes 203682|Planctomycetes S Putative neutral zinc metallopeptidase - - - ko:K07054 - - - - ko00000 - - - Zn_peptidase SYD1_k127_3751045_52 1519464.HY22_07765 3.195e-30 126.0 2CFNZ@1|root,32V3A@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_3751045_65 1150864.MILUP08_40093 5.06e-09 63.0 COG0346@1|root,COG0346@2|Bacteria,2GS59@201174|Actinobacteria,4DGI8@85008|Micromonosporales 201174|Actinobacteria E Glyoxalase bleomycin resistance protein dioxygenase - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase,Glyoxalase_2 SYD1_k127_3751045_17 357808.RoseRS_1484 9.043e-125 407.0 COG0604@1|root,COG0604@2|Bacteria,2G6KH@200795|Chloroflexi,3763V@32061|Chloroflexia 32061|Chloroflexia C PFAM Alcohol dehydrogenase zinc-binding domain protein - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N SYD1_k127_3751045_27 1237149.C900_05249 1.096e-70 257.0 COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,47PK1@768503|Cytophagia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - Gly-zipper_Omp,OmpA,PD40 SYD1_k127_3751045_48 1150469.RSPPHO_03037 8.864e-34 135.0 COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator - - - ko:K03892,ko:K21903 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 SYD1_k127_3751045_44 1210884.HG799462_gene8245 1.122e-38 150.0 COG0394@1|root,COG0394@2|Bacteria,2J0IQ@203682|Planctomycetes 203682|Planctomycetes T Low molecular weight phosphatase family - - - - - - - - - - - - LMWPc SYD1_k127_3751045_10 1210884.HG799462_gene9129 2.514e-150 490.0 COG0798@1|root,COG0798@2|Bacteria,2IY8H@203682|Planctomycetes 203682|Planctomycetes P COG0798 Arsenite efflux pump ACR3 and related - - - ko:K03325 - - - - ko00000,ko02000 2.A.59 - - SBF SYD1_k127_3751045_60 665571.STHERM_c11400 2.18e-19 95.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis - - - - - - - - - - - - DUF4369,Thioredoxin_3 SYD1_k127_3751045_12 1121406.JAEX01000010_gene1337 6.879e-137 447.0 COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42N6E@68525|delta/epsilon subdivisions,2WJXG@28221|Deltaproteobacteria,2M9VF@213115|Desulfovibrionales 28221|Deltaproteobacteria S Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 SYD1_k127_3751045_71 1123248.KB893370_gene5153 3.453e-05 51.0 COG1359@1|root,COG1359@2|Bacteria,4P3Z8@976|Bacteroidetes 976|Bacteroidetes S (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - - - - - - - - - - - SYD1_k127_3751045_33 266117.Rxyl_2946 5.609e-60 218.0 COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria 84995|Rubrobacteria T Transcriptional regulator - - - - - - - - - - - - BTAD,Trans_reg_C SYD1_k127_3751045_36 1097668.BYI23_B012200 1.424e-54 197.0 COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2VSH3@28216|Betaproteobacteria,1K72M@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM DGPFAETKE family protein - - - - - - - - - - - - YCII SYD1_k127_3751045_42 1267534.KB906758_gene2322 1.284e-39 152.0 COG3795@1|root,COG3795@2|Bacteria 2|Bacteria F YCII-related domain - - - - - - - - - - - - YCII SYD1_k127_3751045_7 1242864.D187_005776 2.823e-190 608.0 COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,437V1@68525|delta/epsilon subdivisions,2X34I@28221|Deltaproteobacteria,2YU7X@29|Myxococcales 28221|Deltaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 SYD1_k127_3751045_46 290397.Adeh_2244 3.358e-35 154.0 COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria 1224|Proteobacteria S Doxx family - - - ko:K15977 - - - - ko00000 - - - DoxX SYD1_k127_3751045_23 296591.Bpro_0708 1.087e-96 337.0 COG3447@1|root,COG4585@1|root,COG3447@2|Bacteria,COG4585@2|Bacteria,1PF0H@1224|Proteobacteria,2W8ZC@28216|Betaproteobacteria,4AI7H@80864|Comamonadaceae 28216|Betaproteobacteria T MASE1 - - - - - - - - - - - - HATPase_c,MASE1 SYD1_k127_3751045_28 56780.SYN_01953 1.765e-65 235.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MRIP@213462|Syntrophobacterales 28221|Deltaproteobacteria T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg SYD1_k127_3751045_29 1122201.AUAZ01000040_gene3815 3.111e-65 243.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,4640S@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases yebA - - - - - - - - - - - OapA,OapA_N,Peptidase_M23 SYD1_k127_3751045_49 481448.Minf_1071 5.486e-33 149.0 COG0607@1|root,COG0607@2|Bacteria,46YZI@74201|Verrucomicrobia,37GUH@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia P Rhodanese-like domain - - - - - - - - - - - - Rhodanese SYD1_k127_3751045_4 1183438.GKIL_3722 3.449e-229 732.0 COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria 1117|Cyanobacteria E PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N SYD1_k127_3751045_72 563008.HMPREF0665_00829 6.017e-05 53.0 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - OMP_b-brl,OMP_b-brl_2 SYD1_k127_3751045_51 351607.Acel_1033 5.586e-31 132.0 COG4747@1|root,COG4747@2|Bacteria 2|Bacteria - - hom - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 ko:K00003,ko:K00058,ko:K01754,ko:K04767 ko00260,ko00270,ko00290,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00290,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00017,M00018,M00020,M00570 R00220,R00996,R01513,R01773,R01775 RC00031,RC00087,RC00418,RC02600 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT,CBS,Homoserine_dh,Lactamase_B,NAD_binding_3 SYD1_k127_3751045_18 408672.NBCG_02161 3.872e-121 420.0 COG1215@1|root,COG1215@2|Bacteria,2GKFI@201174|Actinobacteria,4DPBK@85009|Propionibacteriales 201174|Actinobacteria M Glycosyl transferase family group 2 - - 2.4.1.12 ko:K00694 ko00500,ko01100,ko02026,map00500,map01100,map02026 - R02889 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 - Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 SYD1_k127_3751045_9 1379698.RBG1_1C00001G0054 1.669e-183 584.0 COG2502@1|root,COG2502@2|Bacteria,2NNKP@2323|unclassified Bacteria 2|Bacteria E Aspartate-ammonia ligase asnA GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 - R00483 RC00010 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299 AsnA SYD1_k127_3751045_43 1121456.ATVA01000017_gene238 2.628e-39 169.0 COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,43D25@68525|delta/epsilon subdivisions,2X6CE@28221|Deltaproteobacteria 28221|Deltaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec SYD1_k127_3751045_56 459349.CLOAM0604 8.224e-25 122.0 28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_3751045_8 204669.Acid345_0280 1.119e-184 589.0 COG0574@1|root,COG0784@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria,3Y7G5@57723|Acidobacteria 57723|Acidobacteria G Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - - - - - - - - - - PPDK_N SYD1_k127_3828759_11 298654.FraEuI1c_0338 7.641e-06 58.0 COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,2GJRI@201174|Actinobacteria 201174|Actinobacteria T Adenylyl cyclase class-3 4 guanylyl cyclase - - - - - - - - - - - - AAA_16,Guanylate_cyc,TPR_12 SYD1_k127_3828759_16 926556.Echvi_3186 0.0006183 48.0 2DPDF@1|root,331KJ@2|Bacteria,4NWBZ@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - SYD1_k127_3828759_5 765420.OSCT_0924 1.933e-26 122.0 COG0476@1|root,COG0476@2|Bacteria 2|Bacteria H Involved in molybdopterin and thiamine biosynthesis, family 2 - - 2.7.7.80 ko:K21029 ko04122,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - Prok-JAB,ThiF SYD1_k127_3828759_15 1291050.JAGE01000001_gene285 0.0005571 52.0 COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,249UE@186801|Clostridia,3WJGR@541000|Ruminococcaceae 186801|Clostridia M SH3 type 3 domain protein - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - NLPC_P60,SH3_3 SYD1_k127_3828759_8 555088.DealDRAFT_1127 6.481e-17 90.0 COG0739@1|root,COG0739@2|Bacteria,1V32Q@1239|Firmicutes,251MP@186801|Clostridia 186801|Clostridia M Peptidase, M23 - - - - - - - - - - - - Peptidase_M23 SYD1_k127_3828759_7 1158318.ATXC01000001_gene537 1.27e-17 94.0 COG4974@1|root,COG4974@2|Bacteria,2G40X@200783|Aquificae 200783|Aquificae L Belongs to the 'phage' integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase SYD1_k127_3828759_0 1472716.KBK24_0107140 5.116e-133 430.0 COG2267@1|root,COG2267@2|Bacteria,1QTYM@1224|Proteobacteria,2VN3I@28216|Betaproteobacteria,1KGYI@119060|Burkholderiaceae 28216|Betaproteobacteria I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 SYD1_k127_3828759_1 1121015.N789_14020 1.813e-129 424.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1X5QJ@135614|Xanthomonadales 135614|Xanthomonadales E Cys/Met metabolism PLP-dependent enzyme - - 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP SYD1_k127_3828759_4 311403.Arad_0504 5.124e-30 125.0 COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,2UBYC@28211|Alphaproteobacteria,4BC19@82115|Rhizobiaceae 28211|Alphaproteobacteria O Phospholipid methyltransferase - - - - - - - - - - - - PEMT SYD1_k127_3828759_2 1210884.HG799466_gene13015 4.347e-88 304.0 COG0053@1|root,COG0053@2|Bacteria,2IY05@203682|Planctomycetes 203682|Planctomycetes P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - Cation_efflux,ZT_dimer SYD1_k127_3828759_3 1430331.EP10_02635 2.429e-48 178.0 COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,1WETB@129337|Geobacillus 91061|Bacilli FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam SYD1_k127_3828759_12 622637.KE124774_gene2573 7.475e-05 49.0 COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,36XJI@31993|Methylocystaceae 28211|Alphaproteobacteria L Recombinase zinc beta ribbon domain - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom SYD1_k127_3828759_10 1197906.CAJQ02000027_gene1525 2.515e-06 51.0 COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JV1X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Recombinase zinc beta ribbon domain - - - ko:K06400 - - - - ko00000 - - - Recombinase,Resolvase,Zn_ribbon_recom SYD1_k127_3858671_1 1254432.SCE1572_02795 2.751e-95 331.0 COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales 28221|Deltaproteobacteria KLT Protein kinase domain - - - - - - - - - - - - Pkinase SYD1_k127_3858671_0 234267.Acid_2493 6.675e-133 444.0 COG0457@1|root,COG0457@2|Bacteria,3Y46H@57723|Acidobacteria 57723|Acidobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - SYD1_k127_3858671_5 420324.KI912026_gene5022 6.169e-51 205.0 COG0346@1|root,COG0346@2|Bacteria,1RGVH@1224|Proteobacteria,2UAYA@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase SYD1_k127_3858671_8 1121378.KB899715_gene872 8.772e-28 124.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 SYD1_k127_3858671_2 204669.Acid345_2424 2.305e-92 322.0 COG0258@1|root,COG0258@2|Bacteria,3Y2FG@57723|Acidobacteria,2JME1@204432|Acidobacteriia 204432|Acidobacteriia L Helix-hairpin-helix class 2 (Pol1 family) motifs - - - - - - - - - - - - 5_3_exonuc,5_3_exonuc_N SYD1_k127_3858671_3 1211115.ALIQ01000219_gene1380 1.858e-68 241.0 COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,2U97G@28211|Alphaproteobacteria,3NCJ8@45404|Beijerinckiaceae 28211|Alphaproteobacteria J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 SYD1_k127_3910288_8 292415.Tbd_0055 3.027e-22 103.0 COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,2W3S1@28216|Betaproteobacteria 28216|Betaproteobacteria G Protein of unknown function (DUF3365) - - - - - - - - - - - - DUF3365 SYD1_k127_3910288_7 118161.KB235922_gene4297 3.749e-28 127.0 COG0645@1|root,COG0645@2|Bacteria 2|Bacteria S AAA domain - - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - AAA_18,AAA_33,Zeta_toxin SYD1_k127_3910288_9 1519464.HY22_02395 1.646e-18 96.0 COG0730@1|root,COG0730@2|Bacteria 2|Bacteria S response to heat - - - ko:K07090 - - - - ko00000 - - - TauE SYD1_k127_3910288_6 1198452.Jab_1c23560 6.994e-48 180.0 COG4430@1|root,COG4430@2|Bacteria,1RG2R@1224|Proteobacteria 1224|Proteobacteria S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - DUF1801,OmdA SYD1_k127_3910288_5 768710.DesyoDRAFT_1979 2.645e-52 190.0 COG2109@1|root,COG2109@2|Bacteria,1V70U@1239|Firmicutes,24JNB@186801|Clostridia,263QD@186807|Peptococcaceae 186801|Clostridia H PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP - - 2.5.1.17 ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - CobA_CobO_BtuR SYD1_k127_3910288_2 1121430.JMLG01000036_gene165 6.457e-77 276.0 COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,24944@186801|Clostridia,26211@186807|Peptococcaceae 186801|Clostridia E ArgK protein - - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK SYD1_k127_3910288_0 215803.DB30_0533 8.563e-218 706.0 COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria,2YU4T@29|Myxococcales 28221|Deltaproteobacteria I Methylmalonyl-CoA mutase - - 5.4.99.2 ko:K01848 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase SYD1_k127_3910288_3 861299.J421_3347 3.412e-60 210.0 COG2185@1|root,COG2185@2|Bacteria,1ZTNN@142182|Gemmatimonadetes 142182|Gemmatimonadetes I B12 binding domain - - 5.4.99.2 ko:K01849 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding SYD1_k127_3910288_1 1379698.RBG1_1C00001G1461 2.93e-105 348.0 COG1788@1|root,COG1788@2|Bacteria,2NPDX@2323|unclassified Bacteria 2|Bacteria I Coenzyme A transferase scoA - 2.8.3.5,2.8.3.8,2.8.3.9 ko:K01027,ko:K01028,ko:K01034 ko00072,ko00280,ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00627,map00640,map00650,map01100,map01120,map02020 - R00410,R01179,R01359,R01365,R07832 RC00012,RC00014 ko00000,ko00001,ko01000 - - - CoA_trans SYD1_k127_3910288_4 1134413.ANNK01000127_gene2493 2.786e-56 211.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAWZ@91061|Bacilli,1ZCGC@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase yngJ - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N SYD1_k127_391914_8 644966.Tmar_0252 1.41e-75 275.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,25CRT@186801|Clostridia 186801|Clostridia P Rhodanese Homology Domain - - - - - - - - - - - - Lactamase_B,Rhodanese SYD1_k127_391914_7 479434.Sthe_2315 5.231e-81 285.0 COG2855@1|root,COG2855@2|Bacteria,2G98G@200795|Chloroflexi 200795|Chloroflexi S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 SYD1_k127_391914_13 926569.ANT_04400 7.973e-45 176.0 COG0454@1|root,COG1247@1|root,COG0456@2|Bacteria,COG1247@2|Bacteria,2G6N6@200795|Chloroflexi 200795|Chloroflexi K PFAM GCN5-related N-acetyltransferase - - - - - - - - - - - - Acetyltransf_1 SYD1_k127_391914_12 880073.Calab_3446 7.694e-53 214.0 COG0642@1|root,COG2205@2|Bacteria 880073.Calab_3446|- T PhoQ Sensor - - - - - - - - - - - - - SYD1_k127_391914_3 1379270.AUXF01000006_gene39 2.441e-115 402.0 COG1629@1|root,COG4771@2|Bacteria,1ZST4@142182|Gemmatimonadetes 142182|Gemmatimonadetes P CarboxypepD_reg-like domain - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarboxypepD_reg,Plug,TonB_dep_Rec SYD1_k127_391914_17 83406.HDN1F_09590 1.276e-21 97.0 COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,1J7D9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 SYD1_k127_391914_0 1303518.CCALI_01174 1.042e-308 996.0 COG0841@1|root,COG0841@2|Bacteria 2|Bacteria V transmembrane transporter activity - - - - - - - - - - - - ACR_tran SYD1_k127_391914_16 290397.Adeh_3874 6.719e-23 115.0 COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2WKAK@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 SYD1_k127_391914_20 671143.DAMO_1931 5.546e-16 91.0 COG1538@1|root,COG1538@2|Bacteria,2NPKK@2323|unclassified Bacteria 2|Bacteria MU Outer membrane efflux protein - - - - - - - - - - - - OEP SYD1_k127_391914_15 483219.LILAB_00205 8.729e-38 158.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42W7K@68525|delta/epsilon subdivisions,2WRU7@28221|Deltaproteobacteria 28221|Deltaproteobacteria K RNA polymerase - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SYD1_k127_391914_9 1379698.RBG1_1C00001G0708 2.203e-75 267.0 COG0010@1|root,COG0010@2|Bacteria,2NPGU@2323|unclassified Bacteria 2|Bacteria E Arginase family speB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase SYD1_k127_391914_6 1232410.KI421421_gene3677 8.301e-98 345.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,42M7K@68525|delta/epsilon subdivisions,2WKKM@28221|Deltaproteobacteria,43S79@69541|Desulfuromonadales 28221|Deltaproteobacteria J Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM,Methyltransf_25 SYD1_k127_391914_19 1379698.RBG1_1C00001G0404 3.389e-20 98.0 2EAFJ@1|root,334IY@2|Bacteria,2NRZR@2323|unclassified Bacteria 2|Bacteria S Domain of unknown function (DUF1844) - - - - - - - - - - - - DUF1844 SYD1_k127_391914_11 502025.Hoch_2302 1.926e-57 210.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,42R48@68525|delta/epsilon subdivisions,2WMAR@28221|Deltaproteobacteria,2YUR9@29|Myxococcales 28221|Deltaproteobacteria E MazG nucleotide pyrophosphohydrolase domain mazG - 3.6.1.9 ko:K02499,ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG SYD1_k127_391914_5 56780.SYN_01482 3.718e-102 347.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2WIVG@28221|Deltaproteobacteria,2MQVF@213462|Syntrophobacterales 28221|Deltaproteobacteria M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N SYD1_k127_391914_18 1210884.HG799466_gene12319 4.337e-21 110.0 COG0295@1|root,COG0295@2|Bacteria,2J0JM@203682|Planctomycetes 203682|Planctomycetes F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis - - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 SYD1_k127_391914_14 670487.Ocepr_0653 1.759e-44 176.0 COG0274@1|root,COG0274@2|Bacteria,1WI7Y@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC SYD1_k127_391914_4 290397.Adeh_0617 2.3e-113 390.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,42PCD@68525|delta/epsilon subdivisions,2WKGQ@28221|Deltaproteobacteria,2YU9M@29|Myxococcales 28221|Deltaproteobacteria F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis pdp - 2.4.2.2,2.4.2.4 ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R01876,R02296,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C SYD1_k127_391914_10 290397.Adeh_1286 1.734e-62 238.0 COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,43EF3@68525|delta/epsilon subdivisions,2X0ID@28221|Deltaproteobacteria,2Z1N2@29|Myxococcales 28221|Deltaproteobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 SYD1_k127_391914_1 1379698.RBG1_1C00001G1562 2.505e-192 623.0 COG5009@1|root,COG5009@2|Bacteria,2NS4K@2323|unclassified Bacteria 2|Bacteria M Transglycosylase mrcA GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 iAF987.Gmet_0354 PCB_OB,Transgly,Transpeptidase SYD1_k127_391914_2 401526.TcarDRAFT_1799 4.03e-128 424.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H2M0@909932|Negativicutes 909932|Negativicutes J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b SYD1_k127_391914_22 4113.PGSC0003DMT400097405 5.262e-09 59.0 2E4EA@1|root,2S5QZ@2759|Eukaryota,37X8Y@33090|Viridiplantae,3GKGJ@35493|Streptophyta,44UAV@71274|asterids 35493|Streptophyta - - - - - - - - - - - - - - - SYD1_k127_4024737_23 1122138.AQUZ01000012_gene6068 1.264e-36 150.0 COG0454@1|root,COG0456@2|Bacteria,2II3I@201174|Actinobacteria,4DUYZ@85009|Propionibacteriales 201174|Actinobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 SYD1_k127_4024737_6 1047013.AQSP01000098_gene2568 5.637e-127 444.0 COG1042@1|root,COG1042@2|Bacteria,2NNW5@2323|unclassified Bacteria 2|Bacteria C synthetase (ADP forming), alpha - - 6.2.1.13 ko:K01905,ko:K09181,ko:K22224 ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120 - R00229,R00920 RC00004,RC00012,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig SYD1_k127_4024737_15 906968.Trebr_1987 4.5e-56 212.0 COG1014@1|root,COG1014@2|Bacteria,2J7I3@203691|Spirochaetes 203691|Spirochaetes C Pyruvate ferredoxin/flavodoxin oxidoreductase - - 1.2.7.8 ko:K00180 - - - - br01601,ko00000,ko01000 - - - POR SYD1_k127_4024737_4 744872.Spica_1261 1.226e-173 565.0 COG4231@1|root,COG4231@2|Bacteria,2J5C0@203691|Spirochaetes 203691|Spirochaetes C Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates - - 1.2.7.8 ko:K00179 - - - - br01601,ko00000,ko01000 - - - POR_N,TPP_enzyme_C SYD1_k127_4024737_30 292.DM42_5575 3.911e-18 100.0 COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,2VKJT@28216|Betaproteobacteria,1K158@119060|Burkholderiaceae 28216|Betaproteobacteria S Predicted membrane protein (DUF2339) - - - - - - - - - - - - DUF2339 SYD1_k127_4024737_34 37919.EP51_25455 9.419e-09 67.0 2BRIT@1|root,32KHT@2|Bacteria,2IMGR@201174|Actinobacteria,4G76E@85025|Nocardiaceae 201174|Actinobacteria S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 SYD1_k127_4024737_10 1254432.SCE1572_18470 1.249e-83 287.0 COG4122@1|root,COG4122@2|Bacteria,1R4VI@1224|Proteobacteria,42VVN@68525|delta/epsilon subdivisions,2WRTH@28221|Deltaproteobacteria,2YVK4@29|Myxococcales 28221|Deltaproteobacteria S O-methyltransferase - - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 SYD1_k127_4024737_2 404589.Anae109_2747 7.071e-213 690.0 COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2WPT0@28221|Deltaproteobacteria 28221|Deltaproteobacteria O Cytochrome C assembly protein - - - - - - - - - - - - Cytochrom_C_asm,ResB SYD1_k127_4024737_27 1385935.N836_35430 3.533e-27 115.0 2EPF5@1|root,33H1T@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_4024737_12 926550.CLDAP_29200 3.227e-67 241.0 COG1647@1|root,COG1647@2|Bacteria 2|Bacteria M Serine aminopeptidase, S33 - - 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Abhydrolase_6,Hydrolase_4 SYD1_k127_4024737_14 1254432.SCE1572_33370 1.098e-56 206.0 COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,42UAU@68525|delta/epsilon subdivisions 1224|Proteobacteria S TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 cbbY - - - - - - - - - - - HAD_2 SYD1_k127_4024737_35 66377.JOBH01000018_gene2427 6.147e-08 61.0 COG3797@1|root,COG3797@2|Bacteria,2GPDB@201174|Actinobacteria 201174|Actinobacteria I protein conserved in bacteria - - - - - - - - - - - - DUF1697 SYD1_k127_4024737_20 649349.Lbys_1069 4.956e-42 163.0 COG2318@1|root,COG2318@2|Bacteria,4NMJ9@976|Bacteroidetes,47PK4@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1572) - - - - - - - - - - - - DUF1572 SYD1_k127_4024737_13 69395.JQLZ01000006_gene2232 2.802e-64 235.0 2E2V3@1|root,32XWV@2|Bacteria,1MZBD@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SYD1_k127_4024737_18 456442.Mboo_0643 1.423e-49 199.0 COG2208@1|root,arCOG02362@1|root,arCOG02362@2157|Archaea,arCOG06893@2157|Archaea 2157|Archaea KT stage II sporulation - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - HAMP,SpoIIE,dCache_1 SYD1_k127_4024737_22 1396141.BATP01000003_gene5151 1.439e-40 158.0 2A9S7@1|root,30YZS@2|Bacteria,46T8R@74201|Verrucomicrobia 74201|Verrucomicrobia - - - - - - - - - - - - - - - SYD1_k127_4024737_11 99598.Cal7507_6086 5.176e-77 273.0 COG3548@1|root,COG3548@2|Bacteria,1GKP7@1117|Cyanobacteria,1HRK3@1161|Nostocales 1117|Cyanobacteria S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 SYD1_k127_4024737_21 1408224.SAMCCGM7_c4893 7.061e-42 159.0 COG4101@1|root,COG4101@2|Bacteria,1RIFZ@1224|Proteobacteria,2UER9@28211|Alphaproteobacteria,4BDZP@82115|Rhizobiaceae 28211|Alphaproteobacteria G Cupin - - - - - - - - - - - - Cupin_2 SYD1_k127_4024737_33 926569.ANT_11560 3.378e-13 82.0 COG1269@1|root,COG1269@2|Bacteria 2|Bacteria C ATP hydrolysis coupled proton transport - - - - - - - - - - - - PMT_2 SYD1_k127_4024737_16 644966.Tmar_0646 1.265e-52 209.0 COG0438@1|root,COG0438@2|Bacteria,1V0G0@1239|Firmicutes,25BFP@186801|Clostridia 186801|Clostridia M Tetratricopeptide repeat - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SYD1_k127_4024737_0 404380.Gbem_2926 1.224e-233 748.0 COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria,43TEI@69541|Desulfuromonadales 28221|Deltaproteobacteria O Protein of unknown function, DUF255 yyaL - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Thioredox_DsbH SYD1_k127_4024737_9 1254432.SCE1572_52310 5.386e-96 328.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42NVJ@68525|delta/epsilon subdivisions,2WJN1@28221|Deltaproteobacteria,2YUG1@29|Myxococcales 28221|Deltaproteobacteria P Belongs to the ABC transporter superfamily - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE_2 SYD1_k127_4024737_17 511051.CSE_12980 5.913e-52 205.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 SYD1_k127_4024737_37 880073.Calab_0035 0.0001863 54.0 COG2911@1|root,COG4733@1|root,COG2911@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - - - - - - - - - - Big_2,FlgD_ig,SLH SYD1_k127_4024737_24 479434.Sthe_1005 2.668e-35 142.0 COG2867@1|root,COG2867@2|Bacteria 2|Bacteria I negative regulation of translational initiation - - - ko:K05554,ko:K15885 ko01056,ko01130,map01056,map01130 M00778 R09265,R09268 RC02546,RC02547 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Polyketide_cyc,Polyketide_cyc2 SYD1_k127_4024737_5 861299.J421_4185 1.408e-137 450.0 COG0304@1|root,COG0304@2|Bacteria,1ZTE1@142182|Gemmatimonadetes 142182|Gemmatimonadetes I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt SYD1_k127_4024737_32 1123392.AQWL01000001_gene1506 3.707e-14 86.0 COG3794@1|root,COG3794@2|Bacteria,1N0BX@1224|Proteobacteria,2VV36@28216|Betaproteobacteria 28216|Betaproteobacteria C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - - SYD1_k127_4024737_28 1239962.C943_03877 3.93e-25 118.0 COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia 976|Bacteroidetes U WD40-like Beta Propeller Repeat - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - CarbopepD_reg_2,CarboxypepD_reg,PD40 SYD1_k127_4024737_26 648996.Theam_1342 2.905e-30 127.0 COG0406@1|root,COG0406@2|Bacteria,2G423@200783|Aquificae 200783|Aquificae G PFAM Phosphoglycerate mutase pgmA - 3.1.3.3 ko:K22305 ko00260,ko00680,ko01100,ko01120,ko01130,map00260,map00680,map01100,map01120,map01130 - R00582 RC00017 ko00000,ko00001,ko01000 - - - His_Phos_1 SYD1_k127_4024737_8 1267533.KB906735_gene4828 5.573e-113 377.0 COG0136@1|root,COG0136@2|Bacteria,3Y346@57723|Acidobacteria,2JHXJ@204432|Acidobacteriia 204432|Acidobacteriia E Belongs to the aspartate-semialdehyde dehydrogenase family - - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC SYD1_k127_4024737_1 1121430.JMLG01000002_gene1011 1.754e-219 708.0 COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,260BY@186807|Peptococcaceae 186801|Clostridia O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C SYD1_k127_4024737_19 765911.Thivi_4303 3.04e-49 199.0 COG0642@1|root,COG3437@1|root,COG5000@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,COG5000@2|Bacteria,1NRP8@1224|Proteobacteria,1T4M1@1236|Gammaproteobacteria,1WYGE@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - - - - - - - - - - HAMP,HATPase_c,HisKA,Response_reg,dCache_1 SYD1_k127_4024737_29 1403819.BATR01000130_gene4660 8.84e-23 106.0 COG3794@1|root,COG3794@2|Bacteria,46SUG@74201|Verrucomicrobia 74201|Verrucomicrobia C Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg SYD1_k127_4024737_7 1379698.RBG1_1C00001G0178 2.356e-126 420.0 COG2265@1|root,COG2265@2|Bacteria,2NNWX@2323|unclassified Bacteria 2|Bacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr SYD1_k127_4024737_3 316274.Haur_2806 4.135e-184 612.0 COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi,37674@32061|Chloroflexia 32061|Chloroflexia S PFAM peptidase M16 domain protein - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C SYD1_k127_4024737_31 1122605.KB893626_gene2716 1.926e-16 90.0 COG5492@1|root,COG5492@2|Bacteria,4PMF3@976|Bacteroidetes,1IT6W@117747|Sphingobacteriia 976|Bacteroidetes N PFAM Bacterial Ig-like domain (group 2) - - - - - - - - - - - - Beta_helix,CHU_C,VCBS SYD1_k127_4058564_53 1121930.AQXG01000002_gene2041 6.834e-13 81.0 COG3693@1|root,COG3693@2|Bacteria 2|Bacteria G endo-1,4-beta-xylanase activity - - - - - - - - - - - - CBM_2,CBM_6,Esterase,F5_F8_type_C,Glyco_hydro_10,Glyco_hydro_43,Glyco_hydro_9,Glyco_hydro_92,Pec_lyase_C,RicinB_lectin_2,SASA SYD1_k127_4058564_30 251221.35211462 6.902e-65 242.0 COG3291@1|root,COG3291@2|Bacteria,1GFMJ@1117|Cyanobacteria 1117|Cyanobacteria S Pregnancy-associated plasma protein-A - - - - - - - - - - - - Peptidase_M43 SYD1_k127_4058564_14 1379698.RBG1_1C00001G0608 3.498e-95 346.0 COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria 2|Bacteria T Serine threonine protein kinase - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N SYD1_k127_4058564_25 1123261.AXDW01000001_gene1332 6.771e-74 276.0 COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,1RZN8@1236|Gammaproteobacteria,1X97T@135614|Xanthomonadales 135614|Xanthomonadales M Thrombospondin type 3 repeat - - - - - - - - - - - - OMP_b-brl,OmpA,TSP_3 SYD1_k127_4058564_2 469371.Tbis_2768 3.999e-153 500.0 COG0433@1|root,COG0433@2|Bacteria,2GM12@201174|Actinobacteria,4DXWC@85010|Pseudonocardiales 201174|Actinobacteria S Bacterial protein of unknown function (DUF853) - - - ko:K06915 - - - - ko00000 - - - DUF853 SYD1_k127_4058564_46 1121405.dsmv_2371 1.558e-20 98.0 COG0454@1|root,COG0456@2|Bacteria,1N43K@1224|Proteobacteria,42VN3@68525|delta/epsilon subdivisions,2WRDJ@28221|Deltaproteobacteria,2MNCT@213118|Desulfobacterales 28221|Deltaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 SYD1_k127_4058564_21 349521.HCH_02499 4.684e-80 290.0 COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,1STV6@1236|Gammaproteobacteria,1XQTP@135619|Oceanospirillales 135619|Oceanospirillales S benzoyl-CoA oxygenase - - 1.14.13.208 ko:K15512 ko00362,map00362 - R09555 RC01739 ko00000,ko00001,ko01000 - - - - SYD1_k127_4058564_39 1121015.N789_08235 1.759e-42 166.0 COG0457@1|root,COG0457@2|Bacteria,1N9D5@1224|Proteobacteria,1SAKR@1236|Gammaproteobacteria,1XATQ@135614|Xanthomonadales 135614|Xanthomonadales S Tetratricopeptide repeat - - - - - - - - - - - - - SYD1_k127_4058564_0 861299.J421_6223 2.498e-227 735.0 COG2091@1|root,COG2091@2|Bacteria,1ZUE3@142182|Gemmatimonadetes 142182|Gemmatimonadetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - - SYD1_k127_4058564_51 1038866.KB902789_gene2662 7.556e-16 85.0 COG4319@1|root,COG4319@2|Bacteria,1RF3Q@1224|Proteobacteria,2U78H@28211|Alphaproteobacteria,3JZ1D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S SnoaL-like domain - - - - - - - - - - - - DUF4440 SYD1_k127_4058564_1 502025.Hoch_4734 6.981e-207 666.0 COG1164@1|root,COG1164@2|Bacteria,1Q3C4@1224|Proteobacteria,4393F@68525|delta/epsilon subdivisions,2X49B@28221|Deltaproteobacteria,2YYJ7@29|Myxococcales 28221|Deltaproteobacteria E Oligoendopeptidase f - - - - - - - - - - - - - SYD1_k127_4058564_33 986075.CathTA2_1906 3.28e-54 216.0 COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HGYP@91061|Bacilli 91061|Bacilli M Sortase and related acyltransferases pat - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_4 SYD1_k127_4058564_8 861299.J421_2864 1.816e-127 421.0 COG2133@1|root,COG2133@2|Bacteria 2|Bacteria G pyrroloquinoline quinone binding - - - - - - - - - - - - CBM_2,GSDH SYD1_k127_4058564_27 1278073.MYSTI_02736 4.52e-71 260.0 COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria 1224|Proteobacteria G Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 SYD1_k127_4058564_35 1071679.BG57_14115 1.821e-51 192.0 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2VIXW@28216|Betaproteobacteria,1JZMU@119060|Burkholderiaceae 28216|Betaproteobacteria H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - Hemerythrin,PNP_phzG_C,Putative_PNPOx SYD1_k127_4058564_12 349124.Hhal_0421 1.729e-105 372.0 COG2251@1|root,COG2251@2|Bacteria,1QUUG@1224|Proteobacteria,1T3FR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function(DUF2779) - - - - - - - - - - - - DUF2779 SYD1_k127_4058564_52 1038860.AXAP01000003_gene8182 6.004e-13 83.0 COG3848@1|root,COG3848@2|Bacteria,1R7DS@1224|Proteobacteria,2TTNN@28211|Alphaproteobacteria,3JX6Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Pyruvate phosphate dikinase - - - - - - - - - - - - - SYD1_k127_4058564_10 1120972.AUMH01000004_gene1462 2.993e-110 376.0 COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli 91061|Bacilli E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases dapE - - - - - - - - - - - M20_dimer,Peptidase_M20 SYD1_k127_4058564_50 296591.Bpro_2546 6.276e-16 87.0 COG4960@1|root,COG4960@2|Bacteria,1N7J0@1224|Proteobacteria,2VWBT@28216|Betaproteobacteria,4AFH6@80864|Comamonadaceae 28216|Betaproteobacteria OU Peptidase A24A, prepilin type IV - - 3.4.23.43 ko:K02278 - - - - ko00000,ko01000,ko02035,ko02044 - - - Peptidase_A24 SYD1_k127_4058564_55 68170.KL590477_gene2204 3.891e-09 68.0 COG4961@1|root,COG4961@2|Bacteria 2|Bacteria U PFAM TadE family protein tadE - - ko:K12513 - - - - ko00000,ko02044 - - - TadE SYD1_k127_4058564_41 443143.GM18_2439 1.136e-33 143.0 COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,42S07@68525|delta/epsilon subdivisions,2WNR0@28221|Deltaproteobacteria,43UG0@69541|Desulfuromonadales 28221|Deltaproteobacteria U Flp pilus assembly protein RcpC/CpaB - - - ko:K02279 - - - - ko00000,ko02035,ko02044 - - - ChapFlgA,RcpC,SAF SYD1_k127_4058564_36 1123261.AXDW01000015_gene3408 7.649e-50 193.0 COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,1RQ4U@1236|Gammaproteobacteria,1X59M@135614|Xanthomonadales 135614|Xanthomonadales U Belongs to the GSP D family - - - ko:K02280 - - - - ko00000,ko02035,ko02044 - - - Secretin,T2SS-T3SS_pil_N SYD1_k127_4058564_47 223926.28807415 1.614e-20 103.0 COG4961@1|root,COG4961@2|Bacteria,1R58C@1224|Proteobacteria,1S1A4@1236|Gammaproteobacteria,1XWG5@135623|Vibrionales 135623|Vibrionales U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad SYD1_k127_4058564_42 867903.ThesuDRAFT_00037 6.616e-31 137.0 COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,248CD@186801|Clostridia,3WD86@538999|Clostridiales incertae sedis 186801|Clostridia D AAA domain - - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31,ParA,Response_reg SYD1_k127_4058564_3 472759.Nhal_1426 8.852e-153 496.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,1RP9G@1236|Gammaproteobacteria,1WXRJ@135613|Chromatiales 135613|Chromatiales U type II secretion system protein E - - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - FHA,T2SSE SYD1_k127_4058564_34 1267533.KB906738_gene2057 2.901e-52 198.0 COG4965@1|root,COG4965@2|Bacteria,3Y4RR@57723|Acidobacteria,2JJ91@204432|Acidobacteriia 204432|Acidobacteriia U Type II secretion system - - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF SYD1_k127_4058564_32 1121406.JAEX01000002_gene905 2.264e-59 217.0 COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,42R2X@68525|delta/epsilon subdivisions,2WMU1@28221|Deltaproteobacteria,2MAZ8@213115|Desulfovibrionales 28221|Deltaproteobacteria NU PFAM Type II secretion system F - - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF SYD1_k127_4058564_49 1380390.JIAT01000011_gene2542 3.198e-20 98.0 COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria,4CRQ5@84995|Rubrobacteria 84995|Rubrobacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SYD1_k127_4058564_61 235985.BBPN01000064_gene7400 0.0002801 53.0 COG5662@1|root,COG5662@2|Bacteria,2GQ84@201174|Actinobacteria,2NHBN@228398|Streptacidiphilus 201174|Actinobacteria K Putative zinc-finger - - - - - - - - - - - - zf-HC2 SYD1_k127_4058564_20 1232410.KI421416_gene2620 1.237e-80 277.0 COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,42N8F@68525|delta/epsilon subdivisions,2WK3B@28221|Deltaproteobacteria,43U4Y@69541|Desulfuromonadales 28221|Deltaproteobacteria V ABC-2 family transporter protein - - - ko:K09694 ko02010,map02010 M00252 - - ko00000,ko00001,ko00002,ko02000 3.A.1.102 - - ABC2_membrane SYD1_k127_4058564_17 368407.Memar_0659 3.928e-84 306.0 COG1131@1|root,arCOG00194@2157|Archaea,2XUK9@28890|Euryarchaeota,2N9HU@224756|Methanomicrobia 224756|Methanomicrobia E PFAM ABC transporter related - - - ko:K09695 ko02010,map02010 M00252 - - ko00000,ko00001,ko00002,ko02000 3.A.1.102 - - ABC_tran SYD1_k127_4058564_60 1166018.FAES_5306 5.575e-05 51.0 COG3241@1|root,COG3241@2|Bacteria,4NK3S@976|Bacteroidetes,47ND2@768503|Cytophagia 976|Bacteroidetes C Copper binding proteins, plastocyanin/azurin family - - - - - - - - - - - - Copper-bind SYD1_k127_4058564_48 797303.Natpe_2358 2.095e-20 102.0 COG3332@1|root,arCOG06429@2157|Archaea,2XU65@28890|Euryarchaeota,23UCP@183963|Halobacteria 183963|Halobacteria S Transport and Golgi organisation 2 - - - - - - - - - - - - TANGO2 SYD1_k127_4058564_4 251221.35213582 1.15e-149 486.0 COG0372@1|root,COG0372@2|Bacteria,1G1DI@1117|Cyanobacteria 1117|Cyanobacteria C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - iJN678.gltA Citrate_synt SYD1_k127_4058564_11 1121920.AUAU01000004_gene672 1.334e-105 354.0 COG3342@1|root,COG3342@2|Bacteria,3Y80E@57723|Acidobacteria 57723|Acidobacteria S Family of unknown function (DUF1028) - - - - - - - - - - - - DUF1028 SYD1_k127_4058564_13 247490.KSU1_C0449 4.877e-98 342.0 COG2931@1|root,COG2931@2|Bacteria 2|Bacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - Cadherin_3,DUF4347,Peptidase_S8 SYD1_k127_4058564_54 880073.Calab_3215 7.432e-12 78.0 COG0366@1|root,COG0708@1|root,COG0366@2|Bacteria,COG0708@2|Bacteria,2NREA@2323|unclassified Bacteria 2|Bacteria G Glycosyl hydrolase family 70 - - 3.1.11.2,3.2.1.1 ko:K01142,ko:K01176 ko00500,ko01100,ko03410,ko04973,map00500,map01100,map03410,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000,ko03400 - GH13 - Alpha-amylase,CBM_25,DUF1939,He_PIG SYD1_k127_4058564_5 309799.DICTH_0538 5.22e-143 465.0 COG0156@1|root,COG0156@2|Bacteria 2|Bacteria E 8-amino-7-oxononanoate synthase activity bioF GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 SYD1_k127_4058564_15 215803.DB30_0528 3.327e-94 337.0 COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales 28221|Deltaproteobacteria K acetyltransferase - - - - - - - - - - - - - SYD1_k127_4058564_31 1379698.RBG1_1C00001G0531 3.266e-61 236.0 COG0451@1|root,COG0451@2|Bacteria,2NPC7@2323|unclassified Bacteria 2|Bacteria GM NAD(P)H-binding JD73_00815 - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase SYD1_k127_4058564_45 880072.Desac_0873 4.581e-22 108.0 COG1463@1|root,COG1463@2|Bacteria,1MY8D@1224|Proteobacteria,42TCA@68525|delta/epsilon subdivisions,2WP6I@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q ABC-type transport system involved in resistance to organic solvents periplasmic component - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD SYD1_k127_4058564_29 1125863.JAFN01000001_gene565 8.869e-66 233.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q ABC transporter - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran SYD1_k127_4058564_38 1408419.JHYG01000005_gene560 9.981e-46 176.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,2JPB2@204441|Rhodospirillales 204441|Rhodospirillales Q COG0767 ABC-type transport system involved in resistance to organic solvents, permease component - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE SYD1_k127_4058564_26 926569.ANT_14920 8.152e-73 251.0 COG3000@1|root,COG3000@2|Bacteria 2|Bacteria I iron ion binding - - - - - - - - - - - - FA_hydroxylase SYD1_k127_4058564_44 1120973.AQXL01000126_gene2955 5.917e-24 111.0 COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,4HAJ3@91061|Bacilli,2782T@186823|Alicyclobacillaceae 91061|Bacilli H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM SYD1_k127_4058564_37 1385515.N791_08360 7.447e-49 177.0 COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,1X6I0@135614|Xanthomonadales 135614|Xanthomonadales H synthase ptpS - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS SYD1_k127_4058564_40 937777.Deipe_2737 2.828e-36 141.0 COG0662@1|root,COG0662@2|Bacteria 2|Bacteria G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 SYD1_k127_4058564_22 1242864.D187_000224 1.036e-78 279.0 COG1232@1|root,COG1232@2|Bacteria,1R0KQ@1224|Proteobacteria,42NBG@68525|delta/epsilon subdivisions,2WKMN@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemY - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase SYD1_k127_4058564_18 1232410.KI421415_gene3101 8.125e-84 307.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2WMJ2@28221|Deltaproteobacteria,43RXT@69541|Desulfuromonadales 28221|Deltaproteobacteria H Ferrochelatase hemH GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase SYD1_k127_4058564_7 1297742.A176_05045 2.404e-134 458.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,42M87@68525|delta/epsilon subdivisions,2WMB0@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN - - - - - - - - - - - HemN_C,Radical_SAM SYD1_k127_4058564_19 1125863.JAFN01000001_gene1119 2.73e-82 302.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2WJZK@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_0016 URO-D SYD1_k127_4058564_6 644966.Tmar_2245 5.612e-139 475.0 COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,3WCHX@538999|Clostridiales incertae sedis 186801|Clostridia H Aminotransferase class-III hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 SYD1_k127_4058564_9 378806.STAUR_4570 4.928e-127 427.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2WJE8@28221|Deltaproteobacteria,2YTTT@29|Myxococcales 28221|Deltaproteobacteria H Belongs to the ALAD family hemB - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD SYD1_k127_4058564_56 235909.GK2644 8.913e-08 65.0 COG1587@1|root,COG1587@2|Bacteria,1UHSJ@1239|Firmicutes,4HFY4@91061|Bacilli,1WF9W@129337|Geobacillus 91061|Bacilli H Uroporphyrinogen-III synthase HemD hemD - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 SYD1_k127_4058564_23 1304885.AUEY01000013_gene3121 5.227e-75 265.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria,2MISN@213118|Desulfobacterales 28221|Deltaproteobacteria H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC SYD1_k127_4058564_16 443143.GM18_3973 1.486e-87 316.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,43SX3@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH SYD1_k127_4058564_43 1191523.MROS_0613 1.256e-28 126.0 COG0755@1|root,COG0755@2|Bacteria 2|Bacteria O cytochrome complex assembly - - - - - - - - - - - - Cytochrom_C_asm SYD1_k127_4058564_58 1489678.RDMS_06330 3.293e-07 58.0 COG2318@1|root,COG2318@2|Bacteria,1WMYT@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Protein of unknown function (DUF664) - - - - - - - - - - - - DinB SYD1_k127_4058564_24 330214.NIDE0494 6.577e-74 257.0 COG1573@1|root,COG1573@2|Bacteria 2|Bacteria L deaminated base DNA N-glycosylase activity udgB GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF4130,UDG SYD1_k127_4058564_28 1120949.KB903299_gene5889 9.362e-67 246.0 COG0604@1|root,COG0604@2|Bacteria,2GK40@201174|Actinobacteria,4DH8E@85008|Micromonosporales 201174|Actinobacteria C Zinc-binding dehydrogenase fadB5 - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 SYD1_k127_4058564_59 246197.MXAN_7502 1.398e-06 59.0 COG3832@1|root,COG3832@2|Bacteria 2|Bacteria J glyoxalase III activity yndB - - - - - - - - - - - AHSA1 SYD1_k127_497875_0 521096.Tpau_1416 2.243e-06 59.0 COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria 201174|Actinobacteria E amino acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2,AA_permease_C SYD1_k127_5032262_6 1134445.AJJM01000018_gene230 1.284e-12 71.0 COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria 201174|Actinobacteria K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N SYD1_k127_5032262_3 525246.HMPREF0058_1493 4.7e-37 153.0 COG0697@1|root,COG0697@2|Bacteria,2I8X5@201174|Actinobacteria,4D5HU@85005|Actinomycetales 201174|Actinobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA SYD1_k127_5032262_4 754477.Q7C_2156 2.371e-25 109.0 COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,460WA@72273|Thiotrichales 72273|Thiotrichales D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB SYD1_k127_5032262_2 323261.Noc_2284 1.295e-42 165.0 COG1993@1|root,COG1993@2|Bacteria,1N0EM@1224|Proteobacteria,1SH3G@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized ACR, COG1993 - - - ko:K09137 - - - - ko00000 - - - DUF190 SYD1_k127_5032262_0 1038860.AXAP01000001_gene6353 1.714e-51 200.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,3JTP1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Aminotransferase class-III - - - - - - - - - - - - Aminotran_3 SYD1_k127_5032262_7 1122175.ATXU01000003_gene680 1.666e-11 77.0 COG0739@1|root,COG0739@2|Bacteria,2GKXN@201174|Actinobacteria,4FKQY@85023|Microbacteriaceae 201174|Actinobacteria M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 SYD1_k127_5032262_1 1379698.RBG1_1C00001G0886 4.664e-49 189.0 COG1686@1|root,COG1686@2|Bacteria,2NPJT@2323|unclassified Bacteria 2|Bacteria M Belongs to the peptidase S11 family pbpG GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.4.16.4 ko:K01286,ko:K07258,ko:K07262 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - iECO103_1326.ECO103_2610,iYL1228.KPN_02573 Peptidase_S11 SYD1_k127_5032262_5 584708.Apau_1129 1.776e-16 89.0 COG0265@1|root,COG0265@2|Bacteria,3TACF@508458|Synergistetes 508458|Synergistetes M TIGRFAM periplasmic serine protease, Do DeqQ family - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 SYD1_k127_5032262_8 1168034.FH5T_02610 0.000105 54.0 COG3210@1|root,COG3507@1|root,COG3210@2|Bacteria,COG3507@2|Bacteria,4NM1V@976|Bacteroidetes,2FNQQ@200643|Bacteroidia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 43 family - - - - - - - - - - - - Glyco_hydro_43 SYD1_k127_5191776_122 1340493.JNIF01000003_gene2481 9.711e-12 65.0 COG0649@1|root,COG0649@2|Bacteria,3Y3AB@57723|Acidobacteria 57723|Acidobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa SYD1_k127_5191776_7 794846.AJQU01000022_gene1457 1.275e-165 533.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2U2JT@28211|Alphaproteobacteria,4BB5D@82115|Rhizobiaceae 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF2 - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB SYD1_k127_5191776_28 379066.GAU_1656 3.818e-105 361.0 COG0243@1|root,COG1034@1|root,COG0243@2|Bacteria,COG1034@2|Bacteria,1ZTDW@142182|Gemmatimonadetes 142182|Gemmatimonadetes C NADH-ubiquinone oxidoreductase-G iron-sulfur binding region - - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3 SYD1_k127_5191776_24 378806.STAUR_2291 4.753e-109 370.0 COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,42UJZ@68525|delta/epsilon subdivisions,2WQCC@28221|Deltaproteobacteria,2YV77@29|Myxococcales 28221|Deltaproteobacteria F adenosine deaminase add - 3.5.4.4 ko:K01488 ko00230,ko01100,ko05340,map00230,map01100,map05340 - R01560,R02556 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase SYD1_k127_5191776_89 864051.BurJ1DRAFT_1479 6.459e-35 147.0 COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,2WHFN@28216|Betaproteobacteria 28216|Betaproteobacteria Q Dimerisation domain - - - - - - - - - - - - Dimerisation2,Methyltransf_2 SYD1_k127_5191776_76 1120973.AQXL01000121_gene107 3.577e-45 171.0 COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4HHRQ@91061|Bacilli,279R7@186823|Alicyclobacillaceae 91061|Bacilli S Metallo-beta-lactamase superfamily glxII - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B SYD1_k127_5191776_42 309807.SRU_2130 5.188e-88 311.0 COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1FJ16@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Bacillithiol biosynthesis BshC bshC - - ko:K22136 - - - - ko00000 - - - BshC SYD1_k127_5191776_14 1382359.JIAL01000001_gene86 5.59e-127 417.0 COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria,2JKK7@204432|Acidobacteriia 204432|Acidobacteriia M glycosyl transferase group 1 - - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 SYD1_k127_5191776_126 768710.DesyoDRAFT_1324 1.779e-08 66.0 COG1316@1|root,COG2247@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG4932@1|root,COG5184@1|root,COG5492@1|root,COG1316@2|Bacteria,COG2247@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,1UKQV@1239|Firmicutes 1239|Firmicutes M Listeria-Bacteroides repeat domain (List_Bact_rpt) - - - - - - - - - - - - Flg_new SYD1_k127_5191776_51 1379698.RBG1_1C00001G1216 7.978e-77 269.0 COG0407@1|root,COG0407@2|Bacteria,2NPIC@2323|unclassified Bacteria 2|Bacteria H Uroporphyrinogen decarboxylase (URO-D) - - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D SYD1_k127_5191776_90 44251.PDUR_17285 2.742e-34 152.0 COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,4HIV1@91061|Bacilli,26XCJ@186822|Paenibacillaceae 91061|Bacilli H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine panD - 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Asp_decarbox SYD1_k127_5191776_25 880072.Desac_2318 1.312e-107 374.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,2MQRK@213462|Syntrophobacterales 28221|Deltaproteobacteria O NfeD-like C-terminal, partner-binding nfeD - - ko:K07403 - - - - ko00000 - - - CLP_protease,NfeD,SDH_sah SYD1_k127_5191776_29 1379698.RBG1_1C00001G1759 8.114e-105 346.0 COG0330@1|root,COG0330@2|Bacteria,2NNUC@2323|unclassified Bacteria 2|Bacteria O prohibitin homologues hflC - - - - - - - - - - - Band_7 SYD1_k127_5191776_94 479434.Sthe_0334 5.459e-29 123.0 COG1956@1|root,COG1956@2|Bacteria,2GA0T@200795|Chloroflexi,27YG6@189775|Thermomicrobia 189775|Thermomicrobia T GAF domain - - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 SYD1_k127_5191776_18 1278073.MYSTI_03731 2.13e-121 430.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2YTYX@29|Myxococcales 28221|Deltaproteobacteria C dihydrolipoamide dehydrogenase lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim SYD1_k127_5191776_30 266117.Rxyl_2548 5.334e-104 350.0 COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4CPF1@84995|Rubrobacteria 84995|Rubrobacteria H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM SYD1_k127_5191776_4 290397.Adeh_3944 1.819e-182 584.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,2YWVA@29|Myxococcales 28221|Deltaproteobacteria P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N SYD1_k127_5191776_13 573370.DMR_19630 4.7e-127 422.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales 28221|Deltaproteobacteria T Two component, sigma54 specific, transcriptional regulator, Fis family - - - ko:K02481,ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_5191776_109 1408428.JNJP01000060_gene856 5.817e-18 100.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,2M7YN@213115|Desulfovibrionales 28221|Deltaproteobacteria O PFAM PpiC-type peptidyl-prolyl cis-trans isomerase nifM - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 SYD1_k127_5191776_62 760568.Desku_0411 3.735e-59 214.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,25ZZS@186807|Peptococcaceae 186801|Clostridia E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC SYD1_k127_5191776_131 562970.Btus_1884 3.996e-05 58.0 COG5184@1|root,COG5184@2|Bacteria,1UM5S@1239|Firmicutes,4ITQP@91061|Bacilli,279WZ@186823|Alicyclobacillaceae 91061|Bacilli DMZ Cadherin-like beta sandwich domain - - - - - - - - - - - - Cadherin-like,SLH SYD1_k127_5191776_132 292459.STH718 8.053e-05 56.0 COG1404@1|root,COG3291@1|root,COG4412@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia 186801|Clostridia O Belongs to the peptidase S8 family - - - ko:K13276,ko:K17734 - - - - ko00000,ko01000,ko01002,ko03110 - - - CarboxypepD_reg,Cu_amine_oxidN1,Inhibitor_I9,PPC,Peptidase_S8 SYD1_k127_5191776_119 459349.CLOAM0172 1.093e-13 85.0 COG2866@1|root,COG2866@2|Bacteria 2|Bacteria E metallocarboxypeptidase activity - - - - - - - - - - - - Peptidase_M14 SYD1_k127_5191776_34 1121468.AUBR01000026_gene2918 6.77e-97 332.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales 186801|Clostridia H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 SYD1_k127_5191776_74 644966.Tmar_1416 2.056e-48 187.0 COG0108@1|root,COG0307@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0307@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,3WCXY@538999|Clostridiales incertae sedis 186801|Clostridia H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS10830 DHBP_synthase,GTP_cyclohydro2 SYD1_k127_5191776_9 518766.Rmar_2056 6.481e-149 492.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,1FIT0@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 SYD1_k127_5191776_77 1340493.JNIF01000003_gene3086 1.467e-44 169.0 COG0054@1|root,COG0054@2|Bacteria,3Y3RR@57723|Acidobacteria 57723|Acidobacteria H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH - 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase SYD1_k127_5191776_96 667014.Thein_1879 2.467e-26 121.0 COG0781@1|root,COG0781@2|Bacteria,2GHUU@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB SYD1_k127_5191776_65 880073.Calab_0215 4.638e-57 207.0 COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria 2|Bacteria T Calcineurin-like phosphoesterase superfamily domain apaH - - - - - - - - - - - Metallophos_2 SYD1_k127_5191776_56 59374.Fisuc_0695 1.545e-64 233.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25 SYD1_k127_5191776_38 861299.J421_3119 4.322e-92 327.0 COG0438@1|root,COG0438@2|Bacteria,1ZTBC@142182|Gemmatimonadetes 142182|Gemmatimonadetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SYD1_k127_5191776_98 370438.PTH_0126 1.721e-25 123.0 COG0392@1|root,COG0392@2|Bacteria,1VDGK@1239|Firmicutes,24Q29@186801|Clostridia,262MZ@186807|Peptococcaceae 186801|Clostridia S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM SYD1_k127_5191776_26 340177.Cag_0197 3.371e-107 388.0 COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,1FDC1@1090|Chlorobi 1090|Chlorobi EG Protein of unknown function (DUF2723) - - - - - - - - - - - - DUF2723 SYD1_k127_5191776_46 1111479.AXAR01000005_gene484 6.909e-83 300.0 COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,4HAN7@91061|Bacilli,279HA@186823|Alicyclobacillaceae 91061|Bacilli GM Male sterility protein ytcB - - - - - - - - - - - Epimerase,GDP_Man_Dehyd SYD1_k127_5191776_36 880073.Calab_1845 1.588e-95 337.0 COG0463@1|root,COG0463@2|Bacteria,2NP2G@2323|unclassified Bacteria 2|Bacteria M Glycosyltransferase like family 2 arnC - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 SYD1_k127_5191776_43 641491.DND132_1483 6.476e-87 300.0 COG0438@1|root,COG0438@2|Bacteria,1N1RZ@1224|Proteobacteria,42UHY@68525|delta/epsilon subdivisions,2WQD7@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SYD1_k127_5191776_78 324925.Ppha_0256 2.916e-44 186.0 COG1216@1|root,COG1216@2|Bacteria,1FEN2@1090|Chlorobi 1090|Chlorobi M PFAM glycosyl transferase family 2 - - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glycos_transf_2 SYD1_k127_5191776_86 765420.OSCT_1804 7.896e-39 159.0 COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SYD1_k127_5191776_84 290318.Cvib_0237 7.404e-40 163.0 COG0438@1|root,COG0438@2|Bacteria,1FE7C@1090|Chlorobi 1090|Chlorobi M glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4 SYD1_k127_5191776_39 324925.Ppha_0260 4.393e-90 331.0 COG5617@1|root,COG5617@2|Bacteria,1FDV6@1090|Chlorobi 1090|Chlorobi S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - YfhO SYD1_k127_5191776_33 1379698.RBG1_1C00001G0996 3.124e-100 333.0 COG0463@1|root,COG0463@2|Bacteria,2NS3Y@2323|unclassified Bacteria 2|Bacteria M Glycosyltransferase like family 2 dpm1 - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 SYD1_k127_5191776_60 1499967.BAYZ01000063_gene6022 3.48e-59 233.0 COG1216@1|root,COG2148@1|root,COG1216@2|Bacteria,COG2148@2|Bacteria,2NP9Z@2323|unclassified Bacteria 2|Bacteria GM Glycosyltransferase like family 2 - - - ko:K03606,ko:K07011 ko05111,map05111 - - - ko00000,ko00001 - - - Bac_transf,CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2 SYD1_k127_5191776_123 1492737.FEM08_14840 5e-11 78.0 COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,1HY9S@117743|Flavobacteriia,2NS82@237|Flavobacterium 976|Bacteroidetes T ABC transporter substrate-binding protein - - - - - - - - - - - - Reg_prop SYD1_k127_5191776_120 1379698.RBG1_1C00001G0382 1.054e-12 83.0 COG5653@1|root,COG5653@2|Bacteria 2|Bacteria M Protein involved in cellulose biosynthesis - - - - - - - - - - - - Acetyltransf_6 SYD1_k127_5191776_80 1379698.RBG1_1C00001G0383 3.442e-42 177.0 COG0438@1|root,COG0438@2|Bacteria,2NQ17@2323|unclassified Bacteria 2|Bacteria M glycosyl transferase group 1 remC - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SYD1_k127_5191776_83 1379698.RBG1_1C00001G0387 2.355e-40 153.0 COG2001@1|root,COG2001@2|Bacteria,2NPTY@2323|unclassified Bacteria 2|Bacteria K MraZ protein, putative antitoxin-like mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ SYD1_k127_5191776_61 448385.sce1657 3.525e-59 216.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2WJ8J@28221|Deltaproteobacteria,2YUXX@29|Myxococcales 28221|Deltaproteobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 SYD1_k127_5191776_32 1379698.RBG1_1C00001G0390 3.265e-101 362.0 COG0768@1|root,COG0768@2|Bacteria,2NNWR@2323|unclassified Bacteria 2|Bacteria M Penicillin-binding Protein dimerisation domain ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - iSSON_1240.SSON_0092 PASTA,PBP_dimer,Transpeptidase SYD1_k127_5191776_12 644966.Tmar_0865 2.378e-128 452.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3WCXE@538999|Clostridiales incertae sedis 186801|Clostridia M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M SYD1_k127_5191776_47 1007103.AFHW01000005_gene4590 5.981e-82 308.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,26S7E@186822|Paenibacillaceae 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M SYD1_k127_5191776_20 1430440.MGMSRv2_2494 3.161e-118 390.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,2JQ3T@204441|Rhodospirillales 204441|Rhodospirillales M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 SYD1_k127_5191776_35 429009.Adeg_1566 8.774e-97 357.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,42EZQ@68295|Thermoanaerobacterales 186801|Clostridia M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M SYD1_k127_5191776_53 1121428.DESHY_50032___1 3.713e-76 282.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2619Y@186807|Peptococcaceae 186801|Clostridia D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE SYD1_k127_5191776_48 1379698.RBG1_1C00001G0396 1.474e-81 286.0 COG0707@1|root,COG0707@2|Bacteria,2NP4Z@2323|unclassified Bacteria 2|Bacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 - R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - GT28 iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Glyco_tran_28_C,Glyco_transf_28 SYD1_k127_5191776_10 443143.GM18_3886 1.307e-144 474.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M SYD1_k127_5191776_124 338966.Ppro_3285 9.134e-10 71.0 COG1589@1|root,COG1589@2|Bacteria,1RDX7@1224|Proteobacteria,42VCZ@68525|delta/epsilon subdivisions,2WRVM@28221|Deltaproteobacteria,43UHQ@69541|Desulfuromonadales 28221|Deltaproteobacteria D Essential cell division protein ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 SYD1_k127_5191776_11 1121918.ARWE01000001_gene878 1.25e-140 459.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,43SXW@69541|Desulfuromonadales 28221|Deltaproteobacteria D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA SYD1_k127_5191776_23 1297581.H919_02752 5.925e-110 385.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,21W5U@150247|Anoxybacillus 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin SYD1_k127_5191776_106 204669.Acid345_0165 5.986e-20 92.0 COG0227@1|root,COG0227@2|Bacteria,3Y5KC@57723|Acidobacteria,2JJYY@204432|Acidobacteriia 204432|Acidobacteriia J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 SYD1_k127_5191776_8 401526.TcarDRAFT_2061 5.758e-149 495.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4H27E@909932|Negativicutes 909932|Negativicutes L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge SYD1_k127_5191776_108 861299.J421_3210 2.731e-18 95.0 2F3JX@1|root,33WDB@2|Bacteria,1ZTZI@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - zinc_ribbon_4 SYD1_k127_5191776_103 1262449.CP6013_0489 1.331e-21 111.0 COG0477@1|root,COG2814@2|Bacteria,1UZPE@1239|Firmicutes,2490R@186801|Clostridia,36EGS@31979|Clostridiaceae 186801|Clostridia EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_3 SYD1_k127_5191776_50 290397.Adeh_2418 3.268e-78 277.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,42PT6@68525|delta/epsilon subdivisions,2WK6I@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM Glycosyl transferase, group 1 - - 2.4.1.345 ko:K08256 - - R11702 - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 SYD1_k127_5191776_101 1125863.JAFN01000001_gene527 2.311e-24 115.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Lipid A biosynthesis acyltransferase htrB - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans SYD1_k127_5191776_134 1089552.KI911559_gene813 0.0002682 51.0 2CCG0@1|root,2ZVGB@2|Bacteria,1P9KG@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SYD1_k127_5191776_55 243231.GSU0099 5.466e-68 248.0 COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria 28221|Deltaproteobacteria S ADP-ribosylation factor family mglA - - ko:K06883 - - - - ko00000 - - - Arf,Ras SYD1_k127_5191776_99 237368.SCABRO_02611 6.401e-25 117.0 COG0457@1|root,COG0457@2|Bacteria,2J306@203682|Planctomycetes 203682|Planctomycetes KLT TPR repeat - - - - - - - - - - - - TPR_11,TPR_16,TPR_8 SYD1_k127_5191776_67 1232410.KI421415_gene3071 7.267e-54 199.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,43TXE@69541|Desulfuromonadales 28221|Deltaproteobacteria E Tryptophan synthase alpha chain trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA SYD1_k127_5191776_100 413816.BBJP01000003_gene185 2.198e-24 115.0 COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,23SVZ@183963|Halobacteria 183963|Halobacteria I Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids ubiA2 - 2.5.1.42 ko:K17105 ko00564,map00564 - R04520 RC01171 ko00000,ko00001,ko01000 - - - UbiA SYD1_k127_5191776_118 1280952.HJA_13595 6.18e-14 83.0 COG1228@1|root,COG4946@1|root,COG1228@2|Bacteria,COG4946@2|Bacteria,1QVGM@1224|Proteobacteria,2TWFQ@28211|Alphaproteobacteria,440P6@69657|Hyphomonadaceae 28211|Alphaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,PD40 SYD1_k127_5191776_116 227377.CBU_1050 9.097e-16 85.0 COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,1JEYY@118969|Legionellales 118969|Legionellales J Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA SYD1_k127_5191776_71 1121396.KB893060_gene2849 4.433e-51 197.0 COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,2MHU3@213118|Desulfobacterales 28221|Deltaproteobacteria T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.13.3 ko:K07709 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_4,PAS_9,sCache_3_2 SYD1_k127_5191776_15 1232410.KI421428_gene1054 3.228e-126 419.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales 28221|Deltaproteobacteria T Domains REC, sigma54 interaction, HTH8 - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_5191776_27 1313304.CALK_1921 1.24e-106 359.0 COG0343@1|root,COG0343@2|Bacteria 2|Bacteria F queuine tRNA-ribosyltransferase activity tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT SYD1_k127_5191776_111 573413.Spirs_3238 5.24e-17 94.0 COG1862@1|root,COG1862@2|Bacteria,2J8D6@203691|Spirochaetes 203691|Spirochaetes U Preprotein translocase, YajC subunit yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC SYD1_k127_5191776_87 187272.Mlg_2628 1.715e-38 151.0 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1WXF4@135613|Chromatiales 135613|Chromatiales J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase SYD1_k127_5191776_59 404380.Gbem_0635 1.31e-62 234.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,43TH3@69541|Desulfuromonadales 28221|Deltaproteobacteria J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N SYD1_k127_5191776_44 1121468.AUBR01000005_gene33 4.39e-84 308.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,42EKD@68295|Thermoanaerobacterales 186801|Clostridia J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun - 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB SYD1_k127_5191776_121 1229780.BN381_70021 1.593e-12 79.0 COG2815@1|root,COG2815@2|Bacteria,2IKFR@201174|Actinobacteria 201174|Actinobacteria S PASTA - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA SYD1_k127_5191776_66 300852.55771488 6.727e-57 218.0 COG0036@1|root,COG0036@2|Bacteria,1WI8K@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G PFAM Ribulose-phosphate 3 epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim SYD1_k127_5191776_41 485913.Krac_5427 2.191e-88 312.0 COG1087@1|root,COG1087@2|Bacteria,2G5QM@200795|Chloroflexi 200795|Chloroflexi M Belongs to the NAD(P)-dependent epimerase dehydratase family - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase SYD1_k127_5191776_49 330214.NIDE2553 1.259e-80 287.0 COG2870@1|root,COG2870@2|Bacteria,3J0GT@40117|Nitrospirae 40117|Nitrospirae M Phosphomethylpyrimidine kinase - - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - PfkB SYD1_k127_5191776_75 575540.Isop_1756 2.9e-46 174.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,2IY6V@203682|Planctomycetes 203682|Planctomycetes H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB SYD1_k127_5191776_127 240015.ACP_3398 4.046e-08 63.0 2E34G@1|root,32Y4J@2|Bacteria,3Y5JB@57723|Acidobacteria,2JJW7@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - SYD1_k127_5191776_2 604354.TSIB_1204 5.741e-196 621.0 COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,24343@183968|Thermococci 183968|Thermococci S CobW/HypB/UreG, nucleotide-binding domain - - - - - - - - - - - - cobW SYD1_k127_5191776_31 1122981.AUME01000058_gene688 2.991e-103 366.0 COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,2FNFG@200643|Bacteroidia 976|Bacteroidetes C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA SYD1_k127_5191776_19 1382356.JQMP01000003_gene1858 2.309e-120 404.0 COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi,27XS4@189775|Thermomicrobia 189775|Thermomicrobia C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA SYD1_k127_5191776_88 290512.Paes_2009 7.433e-36 148.0 COG0105@1|root,COG0105@2|Bacteria,1FDX5@1090|Chlorobi 1090|Chlorobi F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk - 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK SYD1_k127_5191776_110 404380.Gbem_3111 1.916e-17 94.0 COG1399@1|root,COG1399@2|Bacteria,1N7GQ@1224|Proteobacteria,42U2P@68525|delta/epsilon subdivisions,2WRMV@28221|Deltaproteobacteria,43V81@69541|Desulfuromonadales 28221|Deltaproteobacteria S Uncharacterized ACR, COG1399 - - - ko:K07040 - - - - ko00000 - - - DUF177 SYD1_k127_5191776_104 1379698.RBG1_1C00001G1829 8.616e-21 96.0 COG0333@1|root,COG0333@2|Bacteria,2NQ1M@2323|unclassified Bacteria 2|Bacteria J Ribosomal L32p protein family rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p SYD1_k127_5191776_37 635013.TherJR_2078 6.634e-94 323.0 COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae 186801|Clostridia I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis SYD1_k127_5191776_21 370438.PTH_1745 3.128e-113 389.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,260BR@186807|Peptococcaceae 186801|Clostridia I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C SYD1_k127_5191776_54 264732.Moth_0947 1.559e-73 271.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,42EZH@68295|Thermoanaerobacterales 186801|Clostridia I malonyl coa-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 SYD1_k127_5191776_52 903818.KI912268_gene2024 1.368e-76 279.0 COG1028@1|root,COG1028@2|Bacteria,3Y3YM@57723|Acidobacteria 57723|Acidobacteria IQ Short-chain dehydrogenase reductase SDR - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SYD1_k127_5191776_102 1379698.RBG1_1C00001G1825 3.896e-23 110.0 COG0236@1|root,COG0236@2|Bacteria,2NPVJ@2323|unclassified Bacteria 2|Bacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding SYD1_k127_5191776_5 997346.HMPREF9374_0894 6.702e-181 575.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,27B4D@186824|Thermoactinomycetaceae 91061|Bacilli IQ Beta-ketoacyl synthase, C-terminal domain fabF3 - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt SYD1_k127_5191776_68 59374.Fisuc_2018 1.805e-53 201.0 COG0571@1|root,COG0571@2|Bacteria 2|Bacteria J ribonuclease III activity rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm SYD1_k127_5191776_128 243231.GSU1432 7.087e-08 65.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,43U1H@69541|Desulfuromonadales 28221|Deltaproteobacteria S Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8 SYD1_k127_5191776_82 518766.Rmar_1613 2.12e-41 161.0 COG1595@1|root,COG1595@2|Bacteria,4NQE0@976|Bacteroidetes,1FISP@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SYD1_k127_5191776_105 1089550.ATTH01000001_gene2175 5.723e-20 103.0 COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1FIKC@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes O Trypsin htrA - - - - - - - - - - - PDZ_1,PDZ_2,Trypsin_2 SYD1_k127_5191776_130 880073.Calab_1387 1.63e-05 56.0 2DNWK@1|root,32ZJI@2|Bacteria,2NRIM@2323|unclassified Bacteria 2|Bacteria S Domain of unknown function (DUF4837) - - - - - - - - - - - - DUF4837 SYD1_k127_5191776_58 243231.GSU2025 6.423e-63 241.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2WJKR@28221|Deltaproteobacteria,43TT5@69541|Desulfuromonadales 28221|Deltaproteobacteria F Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase,SKI SYD1_k127_5191776_129 316067.Geob_3061 4.691e-07 61.0 COG0457@1|root,COG0457@2|Bacteria,1NEMW@1224|Proteobacteria,42WBX@68525|delta/epsilon subdivisions,2WRAD@28221|Deltaproteobacteria,43VAR@69541|Desulfuromonadales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_8 SYD1_k127_5191776_85 1125863.JAFN01000001_gene2274 7.436e-39 161.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2WP6E@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II SYD1_k127_5191776_92 498761.HM1_0282 1.37e-29 134.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia 186801|Clostridia C carboxylase pycB - 4.1.1.3,6.4.1.1 ko:K01571,ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00217,R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 - - Biotin_lipoyl,HMGL-like,PYC_OADA SYD1_k127_5191776_16 1379698.RBG1_1C00001G1502 4.204e-125 410.0 COG2805@1|root,COG2805@2|Bacteria,2NP0T@2323|unclassified Bacteria 2|Bacteria NU Type II/IV secretion system protein pilT-1 - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE SYD1_k127_5191776_3 1487923.DP73_16685 6.39e-194 614.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,26111@186807|Peptococcaceae 186801|Clostridia I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 SYD1_k127_5191776_73 1379698.RBG1_1C00001G0649 1.507e-48 182.0 COG2045@1|root,COG2045@2|Bacteria,2NPF1@2323|unclassified Bacteria 2|Bacteria H Belongs to the ComB family comB GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 ko:K05979 ko00680,ko01120,map00680,map01120 M00358 R05789 RC00428 ko00000,ko00001,ko00002,ko01000 - - - 2-ph_phosp SYD1_k127_5191776_64 880073.Calab_2504 1.376e-58 231.0 COG0795@1|root,COG0795@2|Bacteria,2NPHN@2323|unclassified Bacteria 2|Bacteria S Permease YjgP YjgQ - - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ SYD1_k127_5191776_40 1379698.RBG1_1C00001G1858 1.821e-88 313.0 COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria 2|Bacteria S Permease YjgP YjgQ family protein lptF GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K07091,ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207 YjgP_YjgQ SYD1_k127_5191776_6 1379698.RBG1_1C00001G0435 7.799e-178 622.0 COG1747@1|root,COG1747@2|Bacteria,2NP33@2323|unclassified Bacteria 2|Bacteria M methyltransferase greA - - - - - - - - - - - GreA_GreB,GreA_GreB_N,SprA_N SYD1_k127_5191776_57 1379698.RBG1_1C00001G0436 2.383e-64 233.0 COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria 2|Bacteria S Peptidase M28 ywaD - - - - - - - - - - - Peptidase_M28 SYD1_k127_5191776_95 1125863.JAFN01000001_gene1427 3.579e-27 118.0 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2WQ0W@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Required for maturation of 30S ribosomal subunits rimP - - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C SYD1_k127_5191776_17 1379698.RBG1_1C00001G1152 1.342e-124 420.0 COG0195@1|root,COG0195@2|Bacteria,2NNV1@2323|unclassified Bacteria 2|Bacteria K Participates in both transcription termination and antitermination nusA GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 SYD1_k127_5191776_1 880526.KE386488_gene1130 2.477e-223 718.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,22UXN@171550|Rikenellaceae 976|Bacteroidetes J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N SYD1_k127_5191776_107 1379698.RBG1_1C00001G1154 1.707e-18 87.0 COG1550@1|root,COG1550@2|Bacteria,2NPYX@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function (DUF503) ylxP - - ko:K09764 - - - - ko00000 - - - DUF503 SYD1_k127_5191776_114 562743.JH976435_gene2989 6.955e-16 83.0 COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli 91061|Bacilli J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA SYD1_k127_5191776_63 1089553.Tph_c11330 6.334e-59 235.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,42ER4@68295|Thermoanaerobacterales 186801|Clostridia S PFAM phosphoesterase, RecJ domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 SYD1_k127_5191776_69 1121405.dsmv_2736 3.194e-53 200.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,2MJFR@213118|Desulfobacterales 28221|Deltaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB_C,TruB_C_2,TruB_N SYD1_k127_5191776_72 330214.NIDE2740 4.284e-49 196.0 COG0196@1|root,COG0196@2|Bacteria,3J0KY@40117|Nitrospirae 40117|Nitrospirae H Riboflavin kinase ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase SYD1_k127_5191776_91 316067.Geob_2696 1.239e-31 128.0 COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,43V8I@69541|Desulfuromonadales 28221|Deltaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 SYD1_k127_5191776_0 1379698.RBG1_1C00001G1160 1.32e-255 810.0 COG1185@1|root,COG1185@2|Bacteria,2NNX7@2323|unclassified Bacteria 2|Bacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 SYD1_k127_5191776_22 871968.DESME_11225 5.355e-110 373.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,260B8@186807|Peptococcaceae 186801|Clostridia S Belongs to the peptidase M16 family ymxG - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C SYD1_k127_5191776_79 331869.BAL199_10435 4.918e-44 181.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,4BQCP@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase SYD1_k127_5191776_97 284031.JNXD01000001_gene4957 1.068e-25 121.0 COG0726@1|root,COG0726@2|Bacteria,2H6C7@201174|Actinobacteria 201174|Actinobacteria G polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 SYD1_k127_5191776_70 1379698.RBG1_1C00001G1249 5.47e-52 199.0 COG3170@1|root,COG3170@2|Bacteria,2NPQF@2323|unclassified Bacteria 2|Bacteria NU Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 SYD1_k127_5191776_45 1232410.KI421414_gene2861 4.446e-83 291.0 COG1899@1|root,COG1899@2|Bacteria,1R3WQ@1224|Proteobacteria,42M57@68525|delta/epsilon subdivisions,2WJ6N@28221|Deltaproteobacteria,43RXI@69541|Desulfuromonadales 28221|Deltaproteobacteria O peptidyl-lysine modification to peptidyl-hypusine - - - - - - - - - - - - - SYD1_k127_5191776_93 316067.Geob_3377 1.579e-29 136.0 COG0392@1|root,COG0392@2|Bacteria,1R98C@1224|Proteobacteria,42U6V@68525|delta/epsilon subdivisions,2WKTZ@28221|Deltaproteobacteria,43W1F@69541|Desulfuromonadales 28221|Deltaproteobacteria S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM SYD1_k127_5191776_125 1209989.TepiRe1_1803 9.733e-09 68.0 COG3307@1|root,COG3307@2|Bacteria,1TQGY@1239|Firmicutes,24AB7@186801|Clostridia,42FXJ@68295|Thermoanaerobacterales 186801|Clostridia M PFAM O-antigen polymerase - - - ko:K18814 - - - - ko00000,ko02000 9.B.67.1 - - Wzy_C SYD1_k127_5191776_115 637905.SVI_1922 7.089e-16 91.0 COG3291@1|root,COG5640@1|root,COG3291@2|Bacteria,COG5640@2|Bacteria,1PDUK@1224|Proteobacteria,1S8QS@1236|Gammaproteobacteria,2Q8NA@267890|Shewanellaceae 1236|Gammaproteobacteria M Pregnancy-associated plasma protein-A - - - - - - - - - - - - PKD,PPC,Peptidase_M43 SYD1_k127_5191776_117 459349.CLOAM0442 1.241e-15 91.0 COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria 2|Bacteria M Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3 SYD1_k127_5191776_112 459349.CLOAM0442 5.637e-17 95.0 COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria 2|Bacteria M Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3 SYD1_k127_5191776_113 880073.Calab_0829 2.245e-16 93.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_3_2,Big_5,Cadherin_3,Cleaved_Adhesin,FlgD_ig,HemolysinCabind,Kelch_1,Kelch_4,OmpA_membrane SYD1_k127_5191776_81 1379698.RBG1_1C00001G0584 3.769e-42 177.0 COG2373@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria 2|Bacteria G gluconolactonase activity - - 3.4.24.40 ko:K01406,ko:K14274,ko:K20276,ko:K21449 ko00040,ko01503,ko02024,map00040,map01503,map02024 - R02427 RC00713 ko00000,ko00001,ko01000,ko01002,ko02000 1.B.40.2 - - Calx-beta,DUF4347,He_PIG,Ice_nucleation,SGL SYD1_k127_5194976_14 1379698.RBG1_1C00001G1225 9.393e-74 254.0 COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria 2|Bacteria J Ribosomal protein S1 rpsA GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 ko:K02945,ko:K03527,ko:K12132 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011 - - - S1 SYD1_k127_5194976_11 671143.DAMO_1213 2.033e-86 304.0 COG0621@1|root,COG0621@2|Bacteria,2NP2U@2323|unclassified Bacteria 2|Bacteria J Uncharacterized protein family UPF0004 yqeV - 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,UPF0004 SYD1_k127_5194976_22 944479.JQLX01000011_gene788 4.891e-27 126.0 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,42UW4@68525|delta/epsilon subdivisions,2WR5T@28221|Deltaproteobacteria,2M6JS@213113|Desulfurellales 28221|Deltaproteobacteria G Tetratricopeptide repeat - - - ko:K19804 - - - - ko00000 - - - TPR_16,TPR_2,TPR_7,TPR_8 SYD1_k127_5194976_29 1123377.AUIV01000007_gene1345 4.579e-05 57.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1X5DD@135614|Xanthomonadales 135614|Xanthomonadales D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB - - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri SYD1_k127_5194976_30 314278.NB231_00974 0.0001824 55.0 COG3147@1|root,COG3147@2|Bacteria,1MXHQ@1224|Proteobacteria,1RRKM@1236|Gammaproteobacteria,1WZKK@135613|Chromatiales 135613|Chromatiales D Sporulation related domain - - - ko:K03749 - - - - ko00000 - - - SPOR SYD1_k127_5194976_1 479434.Sthe_0669 4.197e-201 673.0 COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi,27XRG@189775|Thermomicrobia 189775|Thermomicrobia L that it carries out the mismatch recognition step. This protein has a weak ATPase activity - - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V SYD1_k127_5194976_13 237368.SCABRO_03021 3.193e-74 273.0 COG1044@1|root,COG1044@2|Bacteria,2J4YB@203682|Planctomycetes 203682|Planctomycetes M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - - - - - - - - - - - SYD1_k127_5194976_9 234267.Acid_7185 5.398e-96 342.0 COG3386@1|root,COG3386@2|Bacteria,3Y2G7@57723|Acidobacteria 57723|Acidobacteria G PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - - SYD1_k127_5194976_28 309799.DICTH_1092 2.422e-06 61.0 COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria 2|Bacteria T PFAM metal-dependent phosphohydrolase, HD sub domain - - - - - - - - - - - - GAF,GAF_2,GAF_3,HAMP,HD,HD_5,Response_reg SYD1_k127_5194976_25 1278073.MYSTI_04733 2.899e-11 77.0 COG2199@1|root,COG3706@2|Bacteria,1Q3P7@1224|Proteobacteria,439GE@68525|delta/epsilon subdivisions,2X4SD@28221|Deltaproteobacteria,2YZHR@29|Myxococcales 28221|Deltaproteobacteria T diguanylate cyclase actA - - - - - - - - - - - GGDEF SYD1_k127_5194976_8 926550.CLDAP_06530 3.205e-99 337.0 COG0006@1|root,COG0006@2|Bacteria,2G5J8@200795|Chloroflexi 200795|Chloroflexi E PFAM peptidase M24 - - - - - - - - - - - - Peptidase_M24 SYD1_k127_5194976_7 1379698.RBG1_1C00001G1139 2.591e-104 361.0 COG0323@1|root,COG0323@2|Bacteria,2NNP7@2323|unclassified Bacteria 2|Bacteria L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C SYD1_k127_5194976_16 269799.Gmet_2052 7.004e-71 250.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,43U4M@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT SYD1_k127_5194976_6 477974.Daud_1173 1.971e-105 357.0 COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,260YG@186807|Peptococcaceae 186801|Clostridia C Fe-S oxidoreductase - - - - - - - - - - - - DUF512,PDZ SYD1_k127_5194976_4 696281.Desru_2934 7.582e-129 424.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,2602V@186807|Peptococcaceae 186801|Clostridia S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 SYD1_k127_5194976_20 478741.JAFS01000002_gene421 7.034e-42 162.0 COG0344@1|root,COG0344@2|Bacteria,46VTA@74201|Verrucomicrobia,37GTF@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf SYD1_k127_5194976_10 1121430.JMLG01000010_gene204 1.988e-88 312.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,260KV@186807|Peptococcaceae 186801|Clostridia I PFAM NAD-dependent glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N SYD1_k127_5194976_23 1254432.SCE1572_46635 2.648e-22 101.0 COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,42V1F@68525|delta/epsilon subdivisions,2WR79@28221|Deltaproteobacteria,2Z1R6@29|Myxococcales 28221|Deltaproteobacteria K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 SYD1_k127_5194976_26 1304874.JAFY01000005_gene1522 6.921e-09 67.0 COG1560@1|root,COG1560@2|Bacteria,3TA2D@508458|Synergistetes 508458|Synergistetes M Lipid A biosynthesis acyltransferase - - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans SYD1_k127_5194976_21 497964.CfE428DRAFT_4728 5.365e-31 139.0 COG0463@1|root,COG0463@2|Bacteria,46UW3@74201|Verrucomicrobia 74201|Verrucomicrobia M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 SYD1_k127_5194976_15 671143.DAMO_1380 6.465e-72 265.0 COG0496@1|root,COG0496@2|Bacteria,2NPCG@2323|unclassified Bacteria 2|Bacteria S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - iSFxv_1172.SFxv_3035 SurE SYD1_k127_5194976_17 56780.SYN_01000 1.407e-67 237.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2MQC2@213462|Syntrophobacterales 28221|Deltaproteobacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT SYD1_k127_5194976_24 751945.Theos_0794 1.272e-19 92.0 COG1254@1|root,COG1254@2|Bacteria,1WK7T@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C Belongs to the acylphosphatase family acyP - 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - - Acylphosphatase SYD1_k127_5194976_18 699246.HMPREF0868_0868 4.346e-62 228.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,267PJ@186813|unclassified Clostridiales 186801|Clostridia K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 SYD1_k127_5194976_12 1242864.D187_001577 7.386e-80 293.0 COG3420@1|root,COG3420@2|Bacteria,1R5QH@1224|Proteobacteria 1224|Proteobacteria P lipolytic protein G-D-S-L family - - - - - - - - - - - - Beta_helix SYD1_k127_5194976_3 1121920.AUAU01000004_gene859 3.29e-180 572.0 COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria 57723|Acidobacteria CE Isocitrate/isopropylmalate dehydrogenase - - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh SYD1_k127_5194976_5 1121920.AUAU01000004_gene858 5.02e-116 383.0 COG0119@1|root,COG0119@2|Bacteria,3Y2NJ@57723|Acidobacteria 57723|Acidobacteria E HMGL-like - - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like SYD1_k127_5194976_2 1121920.AUAU01000004_gene857 5.111e-196 618.0 COG1804@1|root,COG1804@2|Bacteria,3Y4ZM@57723|Acidobacteria 57723|Acidobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 SYD1_k127_5194976_0 1121920.AUAU01000004_gene856 1.12e-202 640.0 COG0065@1|root,COG0065@2|Bacteria 2|Bacteria E 3-isopropylmalate dehydratase activity hacA - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase SYD1_k127_5194976_19 1121920.AUAU01000004_gene855 1.035e-54 213.0 COG0066@1|root,COG0066@2|Bacteria 2|Bacteria E 3-isopropylmalate dehydratase activity leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C SYD1_k127_5222254_3 1283287.KB822576_gene4002 1.239e-81 283.0 COG0641@1|root,COG0641@2|Bacteria,2I09P@201174|Actinobacteria,4DWDZ@85009|Propionibacteriales 201174|Actinobacteria C Radical SAM superfamily - - - ko:K06871 - - - - ko00000 - - - Fer4_12,Radical_SAM SYD1_k127_5222254_4 469383.Cwoe_5609 1.941e-69 244.0 COG0558@1|root,COG0558@2|Bacteria,2H9R3@201174|Actinobacteria 201174|Actinobacteria I CDP-alcohol phosphatidyltransferase - - - - - - - - - - - - CDP-OH_P_transf SYD1_k127_5222254_9 76636.JOEC01000002_gene2769 1.891e-27 123.0 COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria,4FNV7@85023|Microbacteriaceae 201174|Actinobacteria G Removes the phosphate from trehalose 6-phosphate to produce free trehalose otsB - 3.1.3.12 ko:K01087 ko00500,ko01100,map00500,map01100 - R02778 RC00017 ko00000,ko00001,ko01000 - - - Trehalose_PPase SYD1_k127_5222254_1 1123508.JH636449_gene7358 1.282e-133 443.0 COG0380@1|root,COG0380@2|Bacteria,2IYNH@203682|Planctomycetes 203682|Planctomycetes G Glycosyltransferase family 20 - - 2.4.1.15,3.1.3.12 ko:K16055 ko00500,ko01100,map00500,map01100 - R02737,R02778 RC00005,RC00017,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 - GT20 - Glyco_transf_20 SYD1_k127_5222254_21 1307761.L21SP2_1768 0.0003198 54.0 COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes 203691|Spirochaetes M ompA family - - - - - - - - - - - - Big_3_3,CHU_C,FlgD_ig,OmpA SYD1_k127_5222254_16 883126.HMPREF9710_02819 1.954e-08 66.0 COG0810@1|root,COG0810@2|Bacteria 2|Bacteria M energy transducer activity - - 2.4.1.18 ko:K00700,ko:K03832 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko02000,ko04147 2.C.1.1 CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48,CarbopepD_reg_2,TonB_2,TonB_C SYD1_k127_5222254_18 441620.Mpop_5304 7.933e-08 60.0 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,1JUEJ@119045|Methylobacteriaceae 28211|Alphaproteobacteria U PFAM Biopolymer transport protein ExbD TolR tolR - - ko:K03559,ko:K03560 - - - - ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 - - ExbD SYD1_k127_5222254_19 864069.MicloDRAFT_00039530 0.0001137 51.0 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,1JUEJ@119045|Methylobacteriaceae 28211|Alphaproteobacteria U PFAM Biopolymer transport protein ExbD TolR tolR - - ko:K03559,ko:K03560 - - - - ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 - - ExbD SYD1_k127_5222254_13 765869.BDW_01675 4.059e-19 104.0 COG0811@1|root,COG0811@2|Bacteria,1NBED@1224|Proteobacteria,42WAH@68525|delta/epsilon subdivisions,2MTKG@213481|Bdellovibrionales,2X5KM@28221|Deltaproteobacteria 213481|Bdellovibrionales U MotA TolQ ExbB proton channel family - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB SYD1_k127_5222254_14 761193.Runsl_4570 6.462e-15 90.0 COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,47JS4@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_2,TPR_21,TPR_6,TPR_8 SYD1_k127_5222254_20 1207063.P24_16812 0.0002124 53.0 COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,2UCHH@28211|Alphaproteobacteria,2JSP2@204441|Rhodospirillales 204441|Rhodospirillales N Required for flagellar hook formation. May act as a scaffolding protein flgD - - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FLgD_tudor,FlgD,FlgD_ig SYD1_k127_5222254_11 1379698.RBG1_1C00001G1334 3.885e-25 120.0 COG2067@1|root,COG2067@2|Bacteria,2NQKU@2323|unclassified Bacteria 2|Bacteria I Tetratricopeptide repeat - - - - - - - - - - - - TPR_2 SYD1_k127_5222254_15 1123508.JH636448_gene7514 9.818e-11 76.0 COG0689@1|root,COG2931@1|root,COG3291@1|root,COG4932@1|root,COG0689@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,2J503@203682|Planctomycetes 203682|Planctomycetes J Domain of unknown function (DUF4465) - - - - - - - - - - - - DUF4465,Dockerin_1 SYD1_k127_5222254_10 1278073.MYSTI_00870 8.091e-26 119.0 COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2YXN2@29|Myxococcales 28221|Deltaproteobacteria GM epimerase dehydratase hpnA - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase SYD1_k127_5222254_2 1123508.JH636439_gene1853 4.864e-130 449.0 COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes 203682|Planctomycetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg SYD1_k127_5222254_0 880073.Calab_3483 3.642e-200 637.0 COG3033@1|root,COG3033@2|Bacteria,2NNZV@2323|unclassified Bacteria 2|Bacteria E Beta-eliminating lyase tnaA - 4.1.99.1 ko:K01667 ko00380,map00380 - R00673 RC00209,RC00355 ko00000,ko00001,ko01000 - - - Beta_elim_lyase SYD1_k127_5222254_5 1415779.JOMH01000001_gene1027 3.961e-63 238.0 COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,1RZN8@1236|Gammaproteobacteria,1X5D2@135614|Xanthomonadales 135614|Xanthomonadales M Thrombospondin type 3 repeat - - - - - - - - - - - - OMP_b-brl,OmpA,TSP_3 SYD1_k127_5222254_12 446466.Cfla_0535 8.997e-21 108.0 COG1610@1|root,COG1610@2|Bacteria,2IFFJ@201174|Actinobacteria,4F2MT@85016|Cellulomonadaceae 201174|Actinobacteria S Yqey-like protein yqeY - - ko:K09117 - - - - ko00000 - - - YqeY SYD1_k127_5222254_8 479434.Sthe_0861 1.512e-28 132.0 COG2519@1|root,COG2519@2|Bacteria 2|Bacteria J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - 2.1.1.304,2.1.1.327 ko:K21103,ko:K21460 ko00405,ko01130,map00405,map01130 M00835 R11533 RC03466 ko00000,ko00001,ko00002,ko01000 - - - Dimerisation2,Methyltransf_2 SYD1_k127_5222254_6 73044.JNXP01000010_gene4766 4.494e-49 200.0 COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria 201174|Actinobacteria L Belongs to the FPG family mutM1 - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS SYD1_k127_5222254_7 1033802.SSPSH_001037 1.382e-40 167.0 COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,1RRRP@1236|Gammaproteobacteria 1236|Gammaproteobacteria MU COG1538 Outer membrane protein cebC - - - - - - - - - - - OEP SYD1_k127_5485720_3 1379698.RBG1_1C00001G1886 1.124e-69 248.0 COG1058@1|root,COG1058@2|Bacteria,2NP0G@2323|unclassified Bacteria 2|Bacteria S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth SYD1_k127_5485720_9 194439.CT0336 4.309e-26 113.0 COG1267@1|root,COG1267@2|Bacteria,1FE6P@1090|Chlorobi 1090|Chlorobi I PFAM phosphatidylglycerophosphatase A - - 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - - PgpA SYD1_k127_5485720_2 378806.STAUR_2690 4.292e-85 287.0 COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales 28221|Deltaproteobacteria S ADP-ribosylation factor family mglA GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - ko:K06883 - - - - ko00000 - - - Arf,Ras SYD1_k127_5485720_6 1379270.AUXF01000005_gene389 4.809e-37 146.0 COG2018@1|root,COG2018@2|Bacteria,1ZTK7@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Roadblock/LC7 domain - - - - - - - - - - - - Robl_LC7 SYD1_k127_5485720_4 1089553.Tph_c28990 3.059e-69 241.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,42F7S@68295|Thermoanaerobacterales 186801|Clostridia L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - HHH,RecR,Toprim_4 SYD1_k127_5485720_5 459349.CLOAM0866 1.621e-55 215.0 28JNG@1|root,2Z9ES@2|Bacteria,2NPDF@2323|unclassified Bacteria 2|Bacteria - - pgsW - - - - - - - - - - - - SYD1_k127_5485720_7 459349.CLOAM0865 1.596e-33 143.0 29EG8@1|root,334DW@2|Bacteria,2NPTE@2323|unclassified Bacteria 2|Bacteria S Capsule biosynthesis CapC capC - - ko:K22116 - - - - ko00000 - - - Caps_synth_CapC SYD1_k127_5485720_1 283942.IL2400 5.755e-92 317.0 COG0769@1|root,COG0769@2|Bacteria,1QYFB@1224|Proteobacteria,1T3Q5@1236|Gammaproteobacteria,2QGQ5@267893|Idiomarinaceae 1236|Gammaproteobacteria M Mur ligase middle domain - - - ko:K01932 - - - - ko00000,ko01000 - - - Mur_ligase_M SYD1_k127_5485720_8 1293054.HSACCH_01736 9.582e-28 115.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,3WATQ@53433|Halanaerobiales 186801|Clostridia S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection - - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd SYD1_k127_5485720_0 1379698.RBG1_1C00001G1659 8.989e-101 353.0 COG2812@1|root,COG2812@2|Bacteria,2NNK7@2323|unclassified Bacteria 2|Bacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 SYD1_k127_5485720_10 1197906.CAJQ02000027_gene1525 1.182e-05 53.0 COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JV1X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Recombinase zinc beta ribbon domain - - - ko:K06400 - - - - ko00000 - - - Recombinase,Resolvase,Zn_ribbon_recom SYD1_k127_56574_1 234267.Acid_5940 1.406e-115 394.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria 57723|Acidobacteria KLTU WD40 domain protein beta Propeller - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase SYD1_k127_56574_2 1448139.AI20_14240 1.983e-57 213.0 COG0457@1|root,COG0457@2|Bacteria,1P0WK@1224|Proteobacteria,1SU5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 SYD1_k127_56574_0 34007.IT40_00800 3.996e-287 903.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,2PUKE@265|Paracoccus 28211|Alphaproteobacteria P E1-E2 ATPase - - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,Hydrolase,YHS SYD1_k127_56574_3 761193.Runsl_5485 8.026e-28 119.0 2A8XY@1|root,30Y1J@2|Bacteria,4NZRD@976|Bacteroidetes,47W74@768503|Cytophagia 976|Bacteroidetes C Photosynthetic reaction centre cytochrome C subunit - - - - - - - - - - - - CytoC_RC SYD1_k127_5764195_11 944435.AXAJ01000005_gene3574 6.139e-119 384.0 COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2VPP0@28216|Betaproteobacteria,1K047@119060|Burkholderiaceae 28216|Betaproteobacteria S Bacterial protein of unknown function (DUF899) - - - - - - - - - - - - DUF899 SYD1_k127_5764195_33 448385.sce5717 2.137e-42 161.0 COG2350@1|root,COG3832@1|root,COG2350@2|Bacteria,COG3832@2|Bacteria,1PN30@1224|Proteobacteria,439Q1@68525|delta/epsilon subdivisions,2WZBZ@28221|Deltaproteobacteria,2Z1T1@29|Myxococcales 28221|Deltaproteobacteria S YCII-related domain - - - - - - - - - - - - YCII SYD1_k127_5764195_53 316274.Haur_4405 1.677e-09 64.0 2DREH@1|root,33BDY@2|Bacteria,2G9NT@200795|Chloroflexi,377SC@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - - SYD1_k127_5764195_38 706587.Desti_3193 5.084e-33 134.0 2DQBG@1|root,335T7@2|Bacteria,1R35T@1224|Proteobacteria,42ZVK@68525|delta/epsilon subdivisions,2WV6B@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - 1.21.4.1 ko:K10794 ko00330,map00330 - R02825 RC00790 ko00000,ko00001,ko01000 - - - GRDB SYD1_k127_5764195_54 880073.Calab_2255 5.899e-06 59.0 COG2067@1|root,COG2067@2|Bacteria 2|Bacteria I long-chain fatty acid transporting porin activity - - - - - - - - - - - - MtrB_PioB SYD1_k127_5764195_28 283942.IL1495 8.217e-53 197.0 2DPEU@1|root,331SS@2|Bacteria,1NDKB@1224|Proteobacteria,1RTE7@1236|Gammaproteobacteria,2QG29@267893|Idiomarinaceae 1236|Gammaproteobacteria S Golgi phosphoprotein 3 (GPP34) - - - - - - - - - - - - GPP34 SYD1_k127_5764195_9 395965.Msil_3336 2.426e-141 457.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria,3NC8C@45404|Beijerinckiaceae 28211|Alphaproteobacteria C Aldo/keto reductase family - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008152,GO:0009987,GO:0015672,GO:0016491,GO:0017144,GO:0030001,GO:0034220,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071704,GO:0071804,GO:0071805,GO:0072527,GO:0098655,GO:0098660,GO:0098662,GO:1901360,GO:1901564 1.1.1.91 ko:K05882 - - - - ko00000,ko01000 - - - Aldo_ket_red SYD1_k127_5764195_13 1158292.JPOE01000005_gene895 2.847e-109 366.0 COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2VJM3@28216|Betaproteobacteria 28216|Betaproteobacteria Q Methyltransferase ubiE_1 - - - - - - - - - - - Methyltransf_11,Methyltransf_25 SYD1_k127_5764195_12 62928.azo1320 5.199e-116 384.0 COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,2VKR0@28216|Betaproteobacteria,2KZS6@206389|Rhodocyclales 206389|Rhodocyclales K Cupin - - - - - - - - - - - - Cupin_6,HTH_18 SYD1_k127_5764195_49 111105.HR09_09100 3.215e-13 80.0 COG3743@1|root,COG3743@2|Bacteria,4NQGZ@976|Bacteroidetes,2FT5C@200643|Bacteroidia,230IQ@171551|Porphyromonadaceae 976|Bacteroidetes S Domain of unknown function (DUF4332) - - - - - - - - - - - - DUF4332,HHH_5 SYD1_k127_5764195_32 867903.ThesuDRAFT_00167 1.317e-45 175.0 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3WCIP@538999|Clostridiales incertae sedis 186801|Clostridia K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 SYD1_k127_5764195_7 1211115.ALIQ01000235_gene2602 6.467e-151 487.0 COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2TT3J@28211|Alphaproteobacteria,3NCBS@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Fic/DOC family N-terminal - - - - - - - - - - - - Fic,Fic_N,HTH_24 SYD1_k127_5764195_56 880073.Calab_3215 0.0006772 53.0 COG0366@1|root,COG0708@1|root,COG0366@2|Bacteria,COG0708@2|Bacteria,2NREA@2323|unclassified Bacteria 2|Bacteria G Glycosyl hydrolase family 70 - - 3.1.11.2,3.2.1.1 ko:K01142,ko:K01176 ko00500,ko01100,ko03410,ko04973,map00500,map01100,map03410,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000,ko03400 - GH13 - Alpha-amylase,CBM_25,DUF1939,He_PIG SYD1_k127_5764195_44 1114856.C496_05572 9.642e-18 98.0 COG5276@1|root,arCOG02565@2157|Archaea,2XUGK@28890|Euryarchaeota,23TB8@183963|Halobacteria 183963|Halobacteria S IMG reference gene - - - - - - - - - - - - LVIVD SYD1_k127_5764195_52 1298867.AUES01000039_gene793 2.194e-10 67.0 COG0640@1|root,COG3832@1|root,COG0640@2|Bacteria,COG3832@2|Bacteria,1RIJ9@1224|Proteobacteria,2U9ZV@28211|Alphaproteobacteria 28211|Alphaproteobacteria K arsR family - - - - - - - - - - - - AHSA1,HTH_20 SYD1_k127_5764195_51 485918.Cpin_5674 2.487e-12 79.0 COG1621@1|root,COG5549@1|root,COG1621@2|Bacteria,COG5549@2|Bacteria,4NGSZ@976|Bacteroidetes,1IUU5@117747|Sphingobacteriia 976|Bacteroidetes O Dual-action HEIGH metallo-peptidase - - - - - - - - - - - - Peptidase_M57 SYD1_k127_5764195_1 379066.GAU_3753 0.0 1105.0 COG0841@1|root,COG0841@2|Bacteria,1ZSN9@142182|Gemmatimonadetes 142182|Gemmatimonadetes V MMPL family - - - - - - - - - - - - ACR_tran SYD1_k127_5764195_22 1379270.AUXF01000007_gene881 2.307e-66 254.0 COG0845@1|root,COG0845@2|Bacteria,1ZUK2@142182|Gemmatimonadetes 142182|Gemmatimonadetes M Biotin-lipoyl like - - - - - - - - - - - - HlyD_D23 SYD1_k127_5764195_18 379066.GAU_3755 1.007e-75 280.0 COG1538@1|root,COG1538@2|Bacteria,1ZU85@142182|Gemmatimonadetes 142182|Gemmatimonadetes MU Outer membrane efflux protein - - - - - - - - - - - - OEP SYD1_k127_5764195_27 204669.Acid345_4024 5.881e-53 194.0 COG1309@1|root,COG1309@2|Bacteria,3Y5TS@57723|Acidobacteria,2JK51@204432|Acidobacteriia 204432|Acidobacteriia K WHG domain - - - - - - - - - - - - TetR_N,WHG SYD1_k127_5764195_10 1300345.LF41_901 1.041e-120 414.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1XDED@135614|Xanthomonadales 135614|Xanthomonadales T Sigma-54 interaction domain - - - - - - - - - - - - HTH_8,Sigma54_activat SYD1_k127_5764195_55 357808.RoseRS_2661 6.997e-05 49.0 2A4K7@1|root,30T6V@2|Bacteria,2GB43@200795|Chloroflexi,377VP@32061|Chloroflexia 32061|Chloroflexia S Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. - - - - - - - - - - - - Frankia_peptide SYD1_k127_5764195_34 1340493.JNIF01000003_gene1952 1.314e-41 173.0 COG0841@1|root,COG0841@2|Bacteria,3Y6DS@57723|Acidobacteria 57723|Acidobacteria V AcrB/AcrD/AcrF family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran,OEP SYD1_k127_5764195_14 243231.GSU2781 1.706e-99 338.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria,43TCG@69541|Desulfuromonadales 28221|Deltaproteobacteria M HlyD family secretion protein - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 SYD1_k127_5764195_0 497964.CfE428DRAFT_2129 0.0 1373.0 COG0841@1|root,COG0841@2|Bacteria,46SDW@74201|Verrucomicrobia 74201|Verrucomicrobia V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran SYD1_k127_5764195_50 640081.Dsui_2348 5.49e-13 76.0 2EIKM@1|root,33CBX@2|Bacteria,1NHWG@1224|Proteobacteria,2W4IF@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - SYD1_k127_5764195_41 2074.JNYD01000023_gene1278 8.366e-31 124.0 COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria,4E5CC@85010|Pseudonocardiales 201174|Actinobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20,HTH_5 SYD1_k127_5764195_31 1242864.D187_004897 7.762e-46 173.0 COG1917@1|root,COG3832@1|root,COG1917@2|Bacteria,COG3832@2|Bacteria,1REB4@1224|Proteobacteria 1224|Proteobacteria S activator of Hsp90 ATPase 1 family protein - - - - - - - - - - - - AHSA1 SYD1_k127_5764195_47 880073.Calab_2038 1.502e-14 85.0 2DEXR@1|root,2ZPPS@2|Bacteria,2NRXB@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_5764195_8 204669.Acid345_2395 1.042e-149 506.0 COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_16,TPR_2,TPR_8 SYD1_k127_5764195_48 397278.JOJN01000012_gene2145 1.629e-14 89.0 COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4DP00@85009|Propionibacteriales 201174|Actinobacteria S Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - DUF5122,Laminin_G_3,Malectin,PKD SYD1_k127_5764195_29 1191523.MROS_0285 5.734e-52 213.0 2E09V@1|root,32VXB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_5764195_45 1121921.KB898706_gene3381 1.471e-15 92.0 COG3291@1|root,COG3325@1|root,COG3979@1|root,COG3291@2|Bacteria,COG3325@2|Bacteria,COG3979@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,2PMUU@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria G Glyco_18 - - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - CBM_5_12,Glyco_hydro_18,PKD,fn3 SYD1_k127_5764195_25 1123508.JH636453_gene5802 9.934e-65 254.0 COG3210@1|root,COG3391@1|root,COG3827@1|root,COG4932@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,COG3827@2|Bacteria,COG4932@2|Bacteria,2IY8U@203682|Planctomycetes 203682|Planctomycetes M Integrin alpha (beta-propellor repeats). - - - - - - - - - - - - VCBS SYD1_k127_5764195_30 1121957.ATVL01000010_gene150 5.856e-50 197.0 COG0189@1|root,COG0189@2|Bacteria,4NGQ4@976|Bacteroidetes,47KCY@768503|Cytophagia 976|Bacteroidetes HJ ligase activity - - - - - - - - - - - - GSH-S_ATP SYD1_k127_5764195_46 373994.Riv7116_3555 1.16e-14 89.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - - - - - - - - - - - Acetyltransf_1 SYD1_k127_5764195_3 1500890.JQNL01000001_gene2475 7.311e-242 783.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,1T1KJ@1236|Gammaproteobacteria,1X478@135614|Xanthomonadales 135614|Xanthomonadales E Prolyl oligopeptidase - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N SYD1_k127_5764195_17 443143.GM18_3259 2.036e-78 273.0 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria 28221|Deltaproteobacteria L PFAM Methyladenine glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco SYD1_k127_5764195_16 477974.Daud_0758 3.676e-80 287.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,2601Y@186807|Peptococcaceae 186801|Clostridia L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH SYD1_k127_5764195_21 1121468.AUBR01000064_gene937 5.133e-68 248.0 COG1801@1|root,COG1801@2|Bacteria,1TPX4@1239|Firmicutes,24F1Y@186801|Clostridia,42G35@68295|Thermoanaerobacterales 186801|Clostridia S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 SYD1_k127_5764195_5 997346.HMPREF9374_0253 8.848e-190 622.0 COG1205@1|root,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,4H9T2@91061|Bacilli 91061|Bacilli L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster yprA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - ko:K06877 - - - - ko00000 - - - DEAD,DUF1998,Helicase_C SYD1_k127_5764195_40 593750.Metfor_2849 4.19e-31 135.0 COG3359@1|root,arCOG03130@2157|Archaea,2Y6XZ@28890|Euryarchaeota,2NARC@224756|Methanomicrobia 224756|Methanomicrobia L RNase_H superfamily - - - ko:K07502 - - - - ko00000 - - - RNase_H_2 SYD1_k127_5764195_37 1173027.Mic7113_3868 2.346e-35 145.0 COG1670@1|root,COG1670@2|Bacteria,1G6CN@1117|Cyanobacteria,1HDSF@1150|Oscillatoriales 1117|Cyanobacteria J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 SYD1_k127_5764195_6 909663.KI867150_gene269 2.234e-181 591.0 COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria,2MSEM@213462|Syntrophobacterales 28221|Deltaproteobacteria E Amino acid permease - - - - - - - - - - - - AA_permease_2 SYD1_k127_5764195_42 1157490.EL26_09360 1.146e-25 109.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,27A9T@186823|Alicyclobacillaceae 91061|Bacilli K Cold-shock protein cspC GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03704 - - - - ko00000,ko03000 - - - CSD SYD1_k127_5764195_20 1379698.RBG1_1C00001G0415 5.738e-69 253.0 COG5316@1|root,COG5316@2|Bacteria,2NPBR@2323|unclassified Bacteria 2|Bacteria S Domain of unknown function (DUF4139) - - - - - - - - - - - - DUF4139 SYD1_k127_5764195_15 1047013.AQSP01000139_gene2416 1.312e-91 323.0 COG1404@1|root,COG1404@2|Bacteria,2NNSK@2323|unclassified Bacteria 2|Bacteria O Subtilase family aprN - - - - - - - - - - - Peptidase_S8 SYD1_k127_5764195_19 768671.ThimaDRAFT_0787 2.251e-69 259.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1WWF8@135613|Chromatiales 135613|Chromatiales F Belongs to the 5'-nucleotidase family - - 3.1.3.5,3.6.1.45 ko:K01081,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos SYD1_k127_5764195_39 768710.DesyoDRAFT_3228 3.708e-31 125.0 COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,265AD@186807|Peptococcaceae 186801|Clostridia K Probable zinc-ribbon domain - - - - - - - - - - - - zf-trcl SYD1_k127_5764195_43 1121428.DESHY_10135___1 2.525e-21 96.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia 186801|Clostridia K Cold shock protein - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD SYD1_k127_5764195_35 1123371.ATXH01000004_gene1748 4.64e-41 175.0 COG0612@1|root,COG0612@2|Bacteria,2GH66@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S Belongs to the peptidase M16 family - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C SYD1_k127_5764195_26 765420.OSCT_2008 1.393e-54 203.0 COG1215@1|root,COG1215@2|Bacteria,2G6E4@200795|Chloroflexi,375A8@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase family 2 - - - - - - - - - - - - Glyco_trans_2_3,Glycos_transf_2 SYD1_k127_5764195_23 880073.Calab_1372 2.431e-65 247.0 COG1624@1|root,COG1624@2|Bacteria,2NPQS@2323|unclassified Bacteria 2|Bacteria S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N,YojJ SYD1_k127_5764195_24 1123229.AUBC01000012_gene2712 3.008e-65 247.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2TTMG@28211|Alphaproteobacteria,3JRVE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15,2.7.6.3 ko:K00796,ko:K13941,ko:K18824 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503 RC00002,RC00017,RC00121,RC00842 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Pterin_bind SYD1_k127_5764195_2 1379698.RBG1_1C00001G1627 1.414e-248 786.0 COG0465@1|root,COG0465@2|Bacteria,2NNQ5@2323|unclassified Bacteria 2|Bacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 SYD1_k127_5764195_36 1120973.AQXL01000119_gene538 1.415e-39 163.0 COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,278AF@186823|Alicyclobacillaceae 91061|Bacilli D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C SYD1_k127_5764195_4 858215.Thexy_0706 3.34e-207 662.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,42EYV@68295|Thermoanaerobacterales 186801|Clostridia F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH,NMO SYD1_k127_5770529_7 518766.Rmar_0414 4.595e-20 100.0 COG3005@1|root,COG3005@2|Bacteria 2|Bacteria C denitrification pathway - - - ko:K02569 - - - - ko00000 - - - Cytochrom_NNT,Paired_CXXCH_1 SYD1_k127_5770529_2 909663.KI867150_gene389 2.95e-103 346.0 COG1216@1|root,COG1216@2|Bacteria,1R50T@1224|Proteobacteria,42P74@68525|delta/epsilon subdivisions,2WK88@28221|Deltaproteobacteria,2MQ8C@213462|Syntrophobacterales 28221|Deltaproteobacteria S Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2,Methyltransf_23 SYD1_k127_5770529_4 1499967.BAYZ01000076_gene842 7.434e-44 179.0 COG0457@1|root,COG0457@2|Bacteria,2NQJ6@2323|unclassified Bacteria 2|Bacteria O Tetratricopeptide repeat - - - - - - - - - - - - TPR_2,TPR_8 SYD1_k127_5770529_6 379066.GAU_3289 9.115e-31 130.0 COG3204@1|root,COG3204@2|Bacteria,1ZUB6@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Lamin Tail Domain - - - - - - - - - - - - LTD SYD1_k127_5770529_1 323259.Mhun_2840 1.532e-139 471.0 COG3291@1|root,arCOG02516@1|root,arCOG03264@1|root,arCOG03606@1|root,arCOG02510@2157|Archaea,arCOG02516@2157|Archaea,arCOG03264@2157|Archaea,arCOG03606@2157|Archaea,2Y7RP@28890|Euryarchaeota,2NBKZ@224756|Methanomicrobia 224756|Methanomicrobia S Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - CARDB,DUF3344,PKD SYD1_k127_5770529_5 379066.GAU_2847 4.55e-42 167.0 2ARQH@1|root,31H1J@2|Bacteria,1ZUJU@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Phosphodiester glycosidase - - - - - - - - - - - - NAGPA SYD1_k127_5770529_8 319225.Plut_1850 4.039e-13 78.0 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - 2.1.1.11,2.1.1.222,2.1.1.64 ko:K00568,ko:K03428 ko00130,ko00860,ko01100,ko01110,map00130,map00860,map01100,map01110 M00117 R04237,R04988,R05614,R08769,R08781 RC00003,RC00392,RC00460,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31 SYD1_k127_5770529_3 404589.Anae109_1819 6.668e-82 281.0 COG1216@1|root,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glycos_transf_2 SYD1_k127_5770529_9 1214065.BAGV01000078_gene1458 1.811e-06 60.0 COG2244@1|root,COG2244@2|Bacteria,1MV5E@1224|Proteobacteria,1RP0A@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Mediates the transbilayer movement of Und-PP-GlcNAc- ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA) wzxE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328,ko:K16693 - - - - ko00000,ko02000 2.A.66.2,2.A.66.2.3 - iSDY_1059.SDY_3956 Polysacc_synt,Polysacc_synt_3 SYD1_k127_5770529_0 861299.J421_0972 5.133e-291 901.0 COG1297@1|root,COG1297@2|Bacteria 2|Bacteria S iron-nicotianamine transmembrane transporter activity oliA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - - - - - - - - - - OPT SYD1_k127_5783110_3 1279009.ADICEAN_02760 1.024e-11 75.0 COG2318@1|root,COG2318@2|Bacteria,4NRAP@976|Bacteroidetes,47NZT@768503|Cytophagia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 SYD1_k127_5783110_2 1267534.KB906754_gene2665 3.509e-40 155.0 2CB8S@1|root,30PE6@2|Bacteria 2|Bacteria S Protein of unknown function (DUF4199) - - - - - - - - - - - - DUF4199 SYD1_k127_5783110_1 639030.JHVA01000001_gene2668 1.18e-100 333.0 COG0262@1|root,COG0262@2|Bacteria 2|Bacteria H dihydrofolate reductase activity - - - - - - - - - - - - RibD_C SYD1_k127_5783110_0 378806.STAUR_6968 4.347e-118 383.0 COG0262@1|root,COG0262@2|Bacteria,1NE59@1224|Proteobacteria 1224|Proteobacteria H RibD C-terminal domain - - - - - - - - - - - - RibD_C SYD1_k127_5885948_16 1501230.ET33_03550 1.636e-05 59.0 COG1404@1|root,COG3291@1|root,COG4412@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,26QNY@186822|Paenibacillaceae 91061|Bacilli O CarboxypepD_reg-like domain bprF - - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,PKD,Peptidase_M6,Peptidase_S8 SYD1_k127_5885948_11 459349.CLOAM1790 2.472e-18 101.0 COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria 2|Bacteria K Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS SYD1_k127_5885948_12 518766.Rmar_1341 7.957e-15 88.0 COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,1FJ2N@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Lamin Tail Domain - - - - - - - - - - - - Big_5,CHU_C,LTD SYD1_k127_5885948_15 1142394.PSMK_12070 3.384e-08 67.0 COG2304@1|root,COG2304@2|Bacteria,2J434@203682|Planctomycetes 203682|Planctomycetes S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - - SYD1_k127_5885948_8 880073.Calab_0680 5.472e-37 149.0 COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria 2|Bacteria T Anti-sigma factor antagonist - - - ko:K04749,ko:K06378 - - - - ko00000,ko03021 - - - STAS,STAS_2 SYD1_k127_5885948_2 880073.Calab_0681 2.368e-151 516.0 COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,2NP51@2323|unclassified Bacteria 2|Bacteria KT Sigma factor PP2C-like phosphatases pkn5 - 2.7.11.1,3.1.3.3 ko:K04757,ko:K07315 - - - - ko00000,ko01000,ko01001,ko03021 - - - AAA_16,GAF,HAMP,HATPase_c_2,Pkinase,SpoIIE,dCache_1 SYD1_k127_5885948_13 880073.Calab_0682 1.865e-14 88.0 COG2067@1|root,COG2067@2|Bacteria,2NQKU@2323|unclassified Bacteria 2|Bacteria I Tetratricopeptide repeat - - - - - - - - - - - - TPR_2 SYD1_k127_5885948_17 215803.DB30_4178 0.0003225 56.0 COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1REF1@1224|Proteobacteria,42Q4N@68525|delta/epsilon subdivisions,2WS51@28221|Deltaproteobacteria,2YWNR@29|Myxococcales 28221|Deltaproteobacteria O Fibronectin type 3 domain - - - - - - - - - - - - Peptidase_M6,Peptidase_S8 SYD1_k127_5885948_14 350054.Mflv_3407 6.528e-13 79.0 COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,236BF@1762|Mycobacteriaceae 201174|Actinobacteria I CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase pgsA2 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf SYD1_k127_5885948_9 653733.Selin_0487 3.038e-34 152.0 COG4885@1|root,COG4885@2|Bacteria 2|Bacteria C Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554 SYD1_k127_5885948_6 1227739.Hsw_2567 1.574e-62 244.0 COG1215@1|root,COG1215@2|Bacteria,4NFM1@976|Bacteroidetes,47M1F@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 SYD1_k127_5885948_0 1267535.KB906767_gene1889 6.725e-314 996.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,3Y2P5@57723|Acidobacteria,2JMA3@204432|Acidobacteriia 204432|Acidobacteriia G PEP-utilising enzyme, mobile domain - - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N SYD1_k127_5885948_5 1089551.KE386572_gene4499 4.015e-66 240.0 COG4448@1|root,COG4448@2|Bacteria,1R4NH@1224|Proteobacteria,2TV9J@28211|Alphaproteobacteria,4BQ8E@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E L-asparaginase II - - - - - - - - - - - - Asparaginase_II SYD1_k127_5885948_1 357808.RoseRS_0829 2.022e-214 677.0 COG1012@1|root,COG1012@2|Bacteria,2G5JZ@200795|Chloroflexi,375DB@32061|Chloroflexia 32061|Chloroflexia C Belongs to the aldehyde dehydrogenase family - - - ko:K22187 ko00040,map00040 - R11768 RC00080 ko00000,ko00001,ko01000 - - - Aldedh SYD1_k127_5885948_10 768706.Desor_2157 4.506e-20 97.0 2E41I@1|root,32YY5@2|Bacteria,1VVZK@1239|Firmicutes,250RQ@186801|Clostridia,265ER@186807|Peptococcaceae 186801|Clostridia - - - - - - - - - - - - - - - SYD1_k127_5885948_7 1121406.JAEX01000003_gene1722 6.245e-44 183.0 COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria,2MBFN@213115|Desulfovibrionales 28221|Deltaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose rfaE - - - - - - - - - - - CTP_transf_like SYD1_k127_5885948_3 1379698.RBG1_1C00001G1507 5.506e-89 304.0 COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria 2|Bacteria M pfkB family carbohydrate kinase rfaE - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB SYD1_k127_5885948_4 1379698.RBG1_1C00001G1216 1.054e-66 257.0 COG0407@1|root,COG0407@2|Bacteria,2NPIC@2323|unclassified Bacteria 2|Bacteria H Uroporphyrinogen decarboxylase (URO-D) - - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D SYD1_k127_5903594_39 204669.Acid345_1922 2.203e-40 154.0 COG2259@1|root,COG2259@2|Bacteria,3Y4XF@57723|Acidobacteria,2JMZV@204432|Acidobacteriia 204432|Acidobacteriia S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX SYD1_k127_5903594_38 251229.Chro_2803 7.624e-41 158.0 COG1846@1|root,COG1846@2|Bacteria,1G6XI@1117|Cyanobacteria 1117|Cyanobacteria K MarR family transcriptional - - - ko:K15973 - - - - ko00000,ko03000 - - - MarR SYD1_k127_5903594_3 237368.SCABRO_03725 2.574e-179 567.0 COG1697@1|root,COG1697@2|Bacteria,2J34C@203682|Planctomycetes 203682|Planctomycetes L Relaxes both positive and negative superturns and exhibits a strong decatenase activity top6A - 5.99.1.3 ko:K03166 - - - - ko00000,ko01000,ko03032 - - - TP6A_N SYD1_k127_5903594_2 237368.SCABRO_03724 4.029e-193 623.0 COG1389@1|root,COG1389@2|Bacteria,2J2A8@203682|Planctomycetes 203682|Planctomycetes L Relaxes both positive and negative superturns and exhibits a strong decatenase activity top6B - 5.99.1.3 ko:K03167 - - - - ko00000,ko01000,ko03032 - - - HATPase_c,Topo-VIb_trans SYD1_k127_5903594_46 269799.Gmet_3401 1.744e-25 123.0 COG2804@1|root,COG2804@2|Bacteria,1NT9A@1224|Proteobacteria,42YPG@68525|delta/epsilon subdivisions,2WUB4@28221|Deltaproteobacteria,43U7U@69541|Desulfuromonadales 28221|Deltaproteobacteria NU PFAM General secretory system II protein E domain protein - - - - - - - - - - - - T2SSE,T2SSE_N SYD1_k127_5903594_11 1000565.METUNv1_03472 6.108e-122 421.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,2KVBG@206389|Rhodocyclales 206389|Rhodocyclales NU twitching motility protein pilT - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE SYD1_k127_5903594_33 1173028.ANKO01000116_gene5724 1.108e-48 182.0 COG0546@1|root,COG0546@2|Bacteria,1G6AW@1117|Cyanobacteria,1HCZI@1150|Oscillatoriales 1117|Cyanobacteria S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 SYD1_k127_5903594_6 1121920.AUAU01000027_gene1480 1.295e-129 460.0 COG0457@1|root,COG0457@2|Bacteria 1121920.AUAU01000027_gene1480|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - SYD1_k127_5903594_57 596151.DesfrDRAFT_0693 2.096e-07 64.0 COG0457@1|root,COG0457@2|Bacteria,1N336@1224|Proteobacteria,42UTQ@68525|delta/epsilon subdivisions,2WQW8@28221|Deltaproteobacteria,2MCP0@213115|Desulfovibrionales 28221|Deltaproteobacteria S SMART Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19 SYD1_k127_5903594_51 290318.Cvib_1284 1.161e-17 95.0 COG1413@1|root,COG1413@2|Bacteria 2|Bacteria C deoxyhypusine monooxygenase activity - - - - - - - - - - - - HEAT_2 SYD1_k127_5903594_10 525904.Tter_2189 5.628e-122 407.0 COG1215@1|root,COG1215@2|Bacteria,2NPD4@2323|unclassified Bacteria 2|Bacteria M PFAM Glycosyl transferase family 2 - - - ko:K00786 - - - - ko00000,ko01000 - - - Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 SYD1_k127_5903594_30 479431.Namu_2374 2.134e-66 257.0 COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria,4EUZ4@85013|Frankiales 201174|Actinobacteria S Immune inhibitor A peptidase M6 - - - - - - - - - - - - Peptidase_M6 SYD1_k127_5903594_56 357808.RoseRS_3008 1.095e-09 72.0 COG0739@1|root,COG2304@1|root,COG4412@1|root,COG0739@2|Bacteria,COG2304@2|Bacteria,COG4412@2|Bacteria,2GB3W@200795|Chloroflexi,377V9@32061|Chloroflexia 32061|Chloroflexia E PFAM von Willebrand factor type A - - 3.4.21.50 ko:K01337 - - - - ko00000,ko01000,ko01002 - - - VWA SYD1_k127_5903594_53 880073.Calab_1441 1.462e-12 82.0 COG4447@1|root,COG4447@2|Bacteria,2NQ6W@2323|unclassified Bacteria 2|Bacteria S Por secretion system C-terminal sorting domain-containing protein - - - - - - - - - - - - FlgD_ig,Sortilin-Vps10 SYD1_k127_5903594_58 383372.Rcas_2702 3.628e-06 59.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_3,Acetyltransf_4 SYD1_k127_5903594_20 671143.DAMO_2120 4.548e-92 332.0 COG0745@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2NQ9F@2323|unclassified Bacteria 2|Bacteria T Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg SYD1_k127_5903594_26 748449.Halha_0441 7.683e-80 288.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia 186801|Clostridia E Family 5 - - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 SYD1_k127_5903594_48 1442599.JAAN01000005_gene897 1.951e-21 110.0 COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria,1X6Z8@135614|Xanthomonadales 135614|Xanthomonadales J RF-1 domain - - - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 SYD1_k127_5903594_15 330214.NIDE0254 2.305e-102 356.0 COG0006@1|root,COG0006@2|Bacteria 2|Bacteria E proline dipeptidase activity - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 SYD1_k127_5903594_18 555088.DealDRAFT_0478 2.867e-98 334.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,42K9Q@68298|Syntrophomonadaceae 186801|Clostridia S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 SYD1_k127_5903594_24 357808.RoseRS_0616 6.185e-86 300.0 COG0006@1|root,COG0006@2|Bacteria,2G5J6@200795|Chloroflexi 200795|Chloroflexi C Metallopeptidase family M24 - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 SYD1_k127_5903594_45 546414.Deide_15080 5.494e-30 133.0 COG1668@1|root,COG1668@2|Bacteria,1WIWF@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus CP ABC-type Na efflux pump, permease component natB - - ko:K09696 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko02000 3.A.1.115 - - ABC2_membrane_2,ABC2_membrane_3 SYD1_k127_5903594_27 452637.Oter_1528 5.13e-77 267.0 COG4555@1|root,COG4555@2|Bacteria 2|Bacteria CP ABC transporter natA - 3.6.3.7 ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 M00253,M00254 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.115 - iYO844.BSU02750 ABC_tran SYD1_k127_5903594_41 102129.Lepto7375DRAFT_3576 1.148e-38 147.0 COG3118@1|root,COG3118@2|Bacteria,1G6KZ@1117|Cyanobacteria,1HBSI@1150|Oscillatoriales 1117|Cyanobacteria O Belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin SYD1_k127_5903594_1 671143.DAMO_2896 5.073e-211 691.0 COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2NNZG@2323|unclassified Bacteria 2|Bacteria L UvrD/REP helicase N-terminal domain - - 3.6.4.12 ko:K03657,ko:K07465 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C SYD1_k127_5903594_5 1379698.RBG1_1C00001G0645 6.469e-131 447.0 COG2031@1|root,COG2031@2|Bacteria 2|Bacteria I Short chain fatty acid transporter atoE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02106 ko02020,map02020 - - - ko00000,ko00001 2.A.73.1 - iECUMN_1333.ECUMN_2561 SCFA_trans SYD1_k127_5903594_25 234267.Acid_1085 5.463e-82 286.0 COG0123@1|root,COG0123@2|Bacteria,3Y46F@57723|Acidobacteria 57723|Acidobacteria BQ Histone deacetylase domain - - - - - - - - - - - - Hist_deacetyl SYD1_k127_5903594_52 926550.CLDAP_23390 8.584e-13 81.0 COG1807@1|root,COG1807@2|Bacteria,2G9BJ@200795|Chloroflexi 2|Bacteria M Protein of unknown function (DUF2723) - - - ko:K14340 - - - - ko00000,ko01000,ko01003 - - - PMT_2 SYD1_k127_5903594_54 880073.Calab_3296 1.71e-12 80.0 COG0737@1|root,COG0737@2|Bacteria 2|Bacteria F nucleotide catabolic process - - 3.4.17.18 ko:K05996 - - - - ko00000,ko01000,ko01002 - - - 5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH SYD1_k127_5903594_14 290397.Adeh_3188 3.037e-112 382.0 COG4412@1|root,COG4412@2|Bacteria 2|Bacteria S peptidase activity, acting on L-amino acid peptides - - - ko:K07004,ko:K09955 - - - - ko00000 - - - Big_4,FTP,Laminin_G_3,PA,Peptidase_M36 SYD1_k127_5903594_0 1156937.MFUM_930013 4.458e-255 796.0 COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,37G43@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 SYD1_k127_5903594_43 1379698.RBG1_1C00001G0288 4.221e-36 139.0 COG0234@1|root,COG0234@2|Bacteria,2NPW2@2323|unclassified Bacteria 2|Bacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 SYD1_k127_5903594_50 1283299.AUKG01000002_gene4691 5.559e-18 99.0 COG1807@1|root,COG1807@2|Bacteria,2HNIC@201174|Actinobacteria,4CPHR@84995|Rubrobacteria 84995|Rubrobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SYD1_k127_5903594_49 661478.OP10G_1618 3.245e-20 102.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase SYD1_k127_5903594_9 665571.STHERM_c05440 7.79e-123 409.0 COG2204@1|root,COG2204@2|Bacteria,2J5NY@203691|Spirochaetes 203691|Spirochaetes T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains rrp-2 - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_5903594_55 945713.IALB_2417 6.443e-11 76.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - - - - - - - - - - ASH,C_GCAxxG_C_C,FlgD_ig,Peptidase_S74 SYD1_k127_5903594_59 595460.RRSWK_07066 8.911e-05 55.0 28W0Q@1|root,2ZI1V@2|Bacteria,2J50H@203682|Planctomycetes 203682|Planctomycetes S Peptidase family C25 - - - - - - - - - - - - Peptidase_C25 SYD1_k127_5903594_47 626418.bglu_1g07830 1.042e-23 104.0 COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,2VXF9@28216|Betaproteobacteria,1KAQV@119060|Burkholderiaceae 28216|Betaproteobacteria L Homeodomain-like domain - - - - - - - - - - - - HTH_Tnp_1 SYD1_k127_5903594_22 246197.MXAN_2122 8.714e-91 311.0 COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,42T3Y@68525|delta/epsilon subdivisions,2WU62@28221|Deltaproteobacteria 28221|Deltaproteobacteria L PFAM Integrase catalytic region - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_3 SYD1_k127_5903594_21 1379698.RBG1_1C00001G0230 6.567e-91 336.0 COG2206@1|root,COG2206@2|Bacteria,2NPP4@2323|unclassified Bacteria 2|Bacteria T Metal dependent phosphohydrolases with conserved 'HD' motif. - - - - - - - - - - - - HD SYD1_k127_5903594_34 404380.Gbem_0250 1.388e-48 198.0 COG1413@1|root,COG1413@2|Bacteria 2|Bacteria C deoxyhypusine monooxygenase activity - - - - - - - - - - - - HEAT_2,HEAT_PBS SYD1_k127_5903594_40 243231.GSU1422 2.329e-40 172.0 COG0419@1|root,COG0419@2|Bacteria,1Q1A7@1224|Proteobacteria,4375R@68525|delta/epsilon subdivisions,2X23H@28221|Deltaproteobacteria,43SPP@69541|Desulfuromonadales 28221|Deltaproteobacteria L AAA domain sbcC-1 - - - - - - - - - - - AAA_23 SYD1_k127_5903594_31 269799.Gmet_1223 1.259e-64 246.0 COG0420@1|root,COG0420@2|Bacteria,1MXMJ@1224|Proteobacteria,42Q5U@68525|delta/epsilon subdivisions,2WINF@28221|Deltaproteobacteria,43SKW@69541|Desulfuromonadales 28221|Deltaproteobacteria L Calcineurin-like phosphoesterase sbcD-1 - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,Metallophos_2 SYD1_k127_5903594_42 1379698.RBG1_1C00001G0634 1.799e-37 150.0 COG1051@1|root,COG1051@2|Bacteria,2NPZ5@2323|unclassified Bacteria 2|Bacteria F NUDIX domain - - - - - - - - - - - - NUDIX,Nudix_N_2 SYD1_k127_5903594_23 1382356.JQMP01000004_gene339 1.58e-88 302.0 COG0648@1|root,COG0648@2|Bacteria,2G5XZ@200795|Chloroflexi,27XEG@189775|Thermomicrobia 189775|Thermomicrobia L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo - 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 SYD1_k127_5903594_19 518766.Rmar_1010 3.745e-93 323.0 COG0778@1|root,COG0778@2|Bacteria,4NQ04@976|Bacteroidetes 976|Bacteroidetes C Nitroreductase - - - - - - - - - - - - Nitroreductase SYD1_k127_5903594_12 1379698.RBG1_1C00001G1752 3.478e-120 406.0 COG0728@1|root,COG0728@2|Bacteria,2NNX8@2323|unclassified Bacteria 2|Bacteria U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN SYD1_k127_5903594_37 395965.Msil_0592 1.946e-42 166.0 COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,2U5JH@28211|Alphaproteobacteria,3NBTM@45404|Beijerinckiaceae 28211|Alphaproteobacteria G Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_6,Hydrolase_like SYD1_k127_5903594_7 1499967.BAYZ01000195_gene3106 2.757e-128 429.0 COG1807@1|root,COG1807@2|Bacteria,2NPZC@2323|unclassified Bacteria 2|Bacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase MA20_19960 - - - - - - - - - - - PMT_2 SYD1_k127_5903594_35 945713.IALB_1477 4.204e-45 191.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 SYD1_k127_5903594_17 118168.MC7420_6518 3.017e-100 374.0 COG0823@1|root,COG1404@1|root,COG2931@1|root,COG0823@2|Bacteria,COG1404@2|Bacteria,COG2931@2|Bacteria,1G04D@1117|Cyanobacteria,1H779@1150|Oscillatoriales 1117|Cyanobacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - Calx-beta,HemolysinCabind,Peptidase_S8,SdrD_B SYD1_k127_5903594_8 309801.trd_A0275 5.797e-124 419.0 COG1351@1|root,COG1351@2|Bacteria,2G9ZK@200795|Chloroflexi,27XV1@189775|Thermomicrobia 189775|Thermomicrobia F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - - - - - - - - - - Thy1 SYD1_k127_5903594_44 1382359.JIAL01000001_gene1071 1.199e-30 123.0 COG0640@1|root,COG0640@2|Bacteria,3Y5UV@57723|Acidobacteria,2JNP2@204432|Acidobacteriia 204432|Acidobacteriia K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 SYD1_k127_5903594_32 338966.Ppro_0069 1.807e-58 214.0 COG1762@1|root,COG1762@2|Bacteria,1RG0Z@1224|Proteobacteria,42RSF@68525|delta/epsilon subdivisions,2WNXB@28221|Deltaproteobacteria,43W0H@69541|Desulfuromonadales 28221|Deltaproteobacteria H PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - HTH_17,PTS_EIIA_2 SYD1_k127_5903594_13 404589.Anae109_3780 8.461e-114 400.0 COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,42NFV@68525|delta/epsilon subdivisions,2WJZ0@28221|Deltaproteobacteria 28221|Deltaproteobacteria CP PFAM NADH Ubiquinone plastoquinone (complex I) - - - ko:K12137 - - - - ko00000,ko01000 - - - Proton_antipo_M,Proton_antipo_N SYD1_k127_5903594_28 290397.Adeh_3656 3.315e-72 262.0 COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,42NHI@68525|delta/epsilon subdivisions,2WJ3D@28221|Deltaproteobacteria,2Z0BP@29|Myxococcales 28221|Deltaproteobacteria C NADH dehydrogenase ehrB - - - - - - - - - - iAF987.Gmet_0374,iAF987.Gmet_2600 NADHdh SYD1_k127_5903594_36 243231.GSU0741 2.636e-44 184.0 COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,42NDW@68525|delta/epsilon subdivisions,2WMF0@28221|Deltaproteobacteria,43SXS@69541|Desulfuromonadales 28221|Deltaproteobacteria C hydrogenase 4 membrane ehrC - - ko:K12140 - - - - ko00000,ko01000 - - - Oxidored_q2 SYD1_k127_5903594_16 404589.Anae109_3784 9.108e-102 357.0 COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,42MG7@68525|delta/epsilon subdivisions,2WIRA@28221|Deltaproteobacteria,2YZXM@29|Myxococcales 28221|Deltaproteobacteria C Proton-conducting membrane transporter ehrD - - ko:K12141 - - - - ko00000,ko01000 - - - Proton_antipo_M SYD1_k127_5903594_4 404589.Anae109_3785 6.24e-143 490.0 COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,42NJH@68525|delta/epsilon subdivisions,2WJ6J@28221|Deltaproteobacteria,2YZIA@29|Myxococcales 28221|Deltaproteobacteria C Respiratory-chain NADH dehydrogenase, 49 Kd subunit ehrL - - - - - - - - - - - Complex1_30kDa,Complex1_49kDa SYD1_k127_5903594_29 404589.Anae109_3786 3.808e-70 244.0 COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,42NH3@68525|delta/epsilon subdivisions,2WJX8@28221|Deltaproteobacteria,2YZYI@29|Myxococcales 28221|Deltaproteobacteria C NADH ubiquinone oxidoreductase, 20 Kd subunit ehrS - - - - - - - - - - iAF987.Gmet_2596 Fer4,Fer4_7,Oxidored_q6 SYD1_k127_5915817_8 649349.Lbys_0687 5.783e-24 120.0 COG3188@1|root,COG3188@2|Bacteria,4NHCJ@976|Bacteroidetes,47K9Y@768503|Cytophagia 976|Bacteroidetes NU usher protein - - - - - - - - - - - - - SYD1_k127_5915817_10 929704.Myrod_3044 3.61e-08 68.0 COG3179@1|root,COG3179@2|Bacteria,4NF8K@976|Bacteroidetes,1HYFJ@117743|Flavobacteriia 976|Bacteroidetes S fibronectin type III domain protein - - - - - - - - - - - - fn3 SYD1_k127_5915817_11 316067.Geob_0814 0.0003585 55.0 COG1361@1|root,COG1520@1|root,COG1657@1|root,COG4257@1|root,COG4733@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1657@2|Bacteria,COG4257@2|Bacteria,COG4733@2|Bacteria,1QYWJ@1224|Proteobacteria,43CDC@68525|delta/epsilon subdivisions,2X7P6@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS SYD1_k127_5915817_3 760192.Halhy_1664 8.75e-134 474.0 2EZ48@1|root,30K0H@2|Bacteria,4P965@976|Bacteroidetes,1IZT0@117747|Sphingobacteriia 760192.Halhy_1664|- S IMG reference gene - - - - - - - - - - - - - SYD1_k127_5915817_2 760192.Halhy_1662 1.772e-150 500.0 2EZ48@1|root,33SAF@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_5915817_1 760192.Halhy_1659 7.087e-170 564.0 2EZ48@1|root,30K0H@2|Bacteria,4P965@976|Bacteroidetes,1IZT0@117747|Sphingobacteriia 760192.Halhy_1659|- S IMG reference gene - - - - - - - - - - - - - SYD1_k127_5915817_0 760192.Halhy_1658 1.617e-174 567.0 2EZ48@1|root,30K0H@2|Bacteria,4P965@976|Bacteroidetes,1IZT0@117747|Sphingobacteriia 760192.Halhy_1658|- S IMG reference gene - - - - - - - - - - - - - SYD1_k127_5915817_5 1121939.L861_16500 8.61e-36 153.0 2DDUQ@1|root,2ZJCQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_5915817_4 760192.Halhy_1667 1.8e-37 162.0 2FKHX@1|root,34C53@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_5915817_9 1267533.KB906737_gene1523 5.425e-18 85.0 COG0399@1|root,COG0399@2|Bacteria,3Y2QT@57723|Acidobacteria,2JKMD@204432|Acidobacteriia 204432|Acidobacteriia E DegT/DnrJ/EryC1/StrS aminotransferase family - - 2.6.1.102 ko:K13010 ko00520,map00520 - R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 - - - DegT_DnrJ_EryC1 SYD1_k127_6259396_19 383372.Rcas_3726 7.918e-28 122.0 COG2345@1|root,COG2345@2|Bacteria,2G79S@200795|Chloroflexi,37750@32061|Chloroflexia 32061|Chloroflexia K PFAM regulatory protein, ArsR - - - - - - - - - - - - HTH_5 SYD1_k127_6259396_16 330214.NIDE0018 8.564e-40 156.0 COG1018@1|root,COG1018@2|Bacteria,3J196@40117|Nitrospirae 40117|Nitrospirae C Oxidoreductase NAD-binding domain - - - - - - - - - - - - - SYD1_k127_6259396_0 483219.LILAB_22395 0.0 1209.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales 28221|Deltaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdA1 - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_2_N,Ribonuc_red_lgC SYD1_k127_6259396_21 1120966.AUBU01000010_gene2880 1.398e-21 109.0 COG2353@1|root,COG2353@2|Bacteria,4NI82@976|Bacteroidetes 976|Bacteroidetes S YceI-like domain - - - - - - - - - - - - YceI SYD1_k127_6259396_22 1379698.RBG1_1C00001G0825 6.147e-20 103.0 28P4Q@1|root,2ZBZV@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_6259396_1 269797.Mbar_A1244 2.543e-158 520.0 COG0520@1|root,arCOG00065@2157|Archaea 2157|Archaea E COG0520 Selenocysteine lyase - - - - - - - - - - - - Aminotran_5 SYD1_k127_6259396_20 1278073.MYSTI_06370 1.199e-25 124.0 COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_16 SYD1_k127_6259396_9 1379698.RBG1_1C00001G0115 3.313e-72 252.0 28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SYD1_k127_6259396_12 247490.KSU1_B0649 2.606e-50 185.0 29ZH8@1|root,30MGZ@2|Bacteria,2J0G3@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - SYD1_k127_6259396_10 1379698.RBG1_1C00001G0113 1.335e-64 231.0 28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SYD1_k127_6259396_15 1379698.RBG1_1C00001G0112 8e-47 191.0 2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - - SYD1_k127_6259396_3 101510.RHA1_ro02716 6.055e-127 459.0 COG0515@1|root,COG2197@1|root,COG3903@1|root,COG0515@2|Bacteria,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FUTU@85025|Nocardiaceae 201174|Actinobacteria K activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - AAA_22,GerE,NB-ARC,Pkinase,TPR_12,TPR_7 SYD1_k127_6259396_6 266117.Rxyl_2946 2.113e-110 391.0 COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria 84995|Rubrobacteria T Transcriptional regulator - - - - - - - - - - - - BTAD,Trans_reg_C SYD1_k127_6259396_4 945713.IALB_0296 4.993e-125 439.0 COG0475@1|root,COG0490@1|root,COG1226@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,COG1226@2|Bacteria 2|Bacteria P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) kefB - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_C,TrkA_N SYD1_k127_6259396_7 1287116.X734_16505 9.847e-96 328.0 COG0520@1|root,COG0520@2|Bacteria,1RB0A@1224|Proteobacteria,2VFZ4@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5,DegT_DnrJ_EryC1 SYD1_k127_6259396_23 330214.NIDE2482 2.513e-19 98.0 COG2146@1|root,COG2146@2|Bacteria,3J1E7@40117|Nitrospirae 40117|Nitrospirae P Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 1.7.1.15 ko:K00363,ko:K05710 ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220 M00530,M00545 R00787,R06782,R06783 RC00098,RC00176 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske SYD1_k127_6259396_18 1303518.CCALI_00819 2.291e-31 128.0 COG0316@1|root,COG0316@2|Bacteria 2|Bacteria S protein maturation - - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn SYD1_k127_6259396_5 760568.Desku_1651 3.049e-116 402.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,260WY@186807|Peptococcaceae 186801|Clostridia G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C SYD1_k127_6259396_11 1379698.RBG1_1C00001G1285 2.247e-53 198.0 COG1225@1|root,COG1225@2|Bacteria,2NPEE@2323|unclassified Bacteria 2|Bacteria O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen bcp GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA SYD1_k127_6259396_17 468059.AUHA01000002_gene268 5.775e-34 141.0 2A6FK@1|root,30V8I@2|Bacteria,4PIJP@976|Bacteroidetes,1ITEW@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - SYD1_k127_6259396_13 926569.ANT_29600 7.963e-50 183.0 COG0695@1|root,COG1225@1|root,COG0695@2|Bacteria,COG1225@2|Bacteria,2G6XD@200795|Chloroflexi 200795|Chloroflexi O Redoxin - - - - - - - - - - - - AhpC-TSA SYD1_k127_6259396_2 289376.THEYE_A0567 4.523e-134 440.0 COG1960@1|root,COG1960@2|Bacteria,3J13U@40117|Nitrospirae 40117|Nitrospirae C Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N SYD1_k127_6259396_14 232346.JHQL01000001_gene2407 2.019e-49 186.0 COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,1S9CM@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the DNA glycosylase MPG family - GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco SYD1_k127_6259396_8 378806.STAUR_6225 2.645e-90 338.0 COG3391@1|root,COG4935@1|root,COG3391@2|Bacteria,COG4935@2|Bacteria,1NUB0@1224|Proteobacteria,43CK0@68525|delta/epsilon subdivisions,2X7UF@28221|Deltaproteobacteria,2Z3HY@29|Myxococcales 28221|Deltaproteobacteria O Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS SYD1_k127_6259396_24 1121930.AQXG01000001_gene1166 3.161e-07 65.0 COG1404@1|root,COG1404@2|Bacteria,4NVH2@976|Bacteroidetes 976|Bacteroidetes O Belongs to the peptidase S8 family - - - - - - - - - - - - - SYD1_k127_6283707_18 404380.Gbem_1249 7.914e-54 198.0 COG2010@1|root,COG2010@2|Bacteria,1RDSI@1224|Proteobacteria,42WEW@68525|delta/epsilon subdivisions 1224|Proteobacteria C cytochrome c norC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02305 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002 3.D.4.10 - - Cytochrom_C SYD1_k127_6283707_2 404589.Anae109_2758 8.743e-186 593.0 COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,42NBM@68525|delta/epsilon subdivisions,2WKTG@28221|Deltaproteobacteria 28221|Deltaproteobacteria P PFAM Cytochrome c oxidase, subunit I - - 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 - - COX1 SYD1_k127_6283707_6 349124.Hhal_1804 7.517e-149 494.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1WW9F@135613|Chromatiales 135613|Chromatiales E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP SYD1_k127_6283707_21 671143.DAMO_1415 1.948e-36 145.0 COG0135@1|root,COG0135@2|Bacteria,2NPIX@2323|unclassified Bacteria 2|Bacteria E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI SYD1_k127_6283707_19 502025.Hoch_3582 8.79e-49 200.0 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,2YV8U@29|Myxococcales 28221|Deltaproteobacteria E Belongs to the TrpC family trpC - 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2494 IGPS SYD1_k127_6283707_11 383372.Rcas_2153 2.753e-84 291.0 COG0547@1|root,COG0547@2|Bacteria,2G5YV@200795|Chloroflexi,375B9@32061|Chloroflexia 32061|Chloroflexia F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 SYD1_k127_6283707_14 335283.Neut_0135 2.336e-69 253.0 COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria,371WE@32003|Nitrosomonadales 28216|Betaproteobacteria EH PFAM Glutamine amidotransferase class-I trpG - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase SYD1_k127_6283707_5 1121918.ARWE01000001_gene2336 1.113e-149 496.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,43T7B@69541|Desulfuromonadales 28221|Deltaproteobacteria EH Anthranilate synthase component I, N terminal region trpE - 4.1.3.27 ko:K01657,ko:K13503 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind SYD1_k127_6283707_10 765910.MARPU_09875 1.273e-87 310.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1WW15@135613|Chromatiales 135613|Chromatiales L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N SYD1_k127_6283707_17 767817.Desgi_2599 2.559e-54 218.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,260CC@186807|Peptococcaceae 186801|Clostridia F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iHN637.CLJU_RS05480 NAD_kinase SYD1_k127_6283707_1 1121428.DESHY_60099___1 1.009e-221 715.0 COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,2604R@186807|Peptococcaceae 186801|Clostridia H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C SYD1_k127_6283707_22 293826.Amet_2506 8.836e-30 134.0 COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,24MV7@186801|Clostridia,36KSA@31979|Clostridiaceae 186801|Clostridia S Divergent PAP2 family - - - ko:K09775 - - - - ko00000 - - - DUF212 SYD1_k127_6283707_13 1125863.JAFN01000001_gene3503 6.568e-74 259.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Belongs to the FPP GGPP synthase family ispA - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt SYD1_k127_6283707_28 278963.ATWD01000001_gene4026 2.231e-08 67.0 COG1722@1|root,COG1722@2|Bacteria 2|Bacteria L exodeoxyribonuclease VII activity xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S SYD1_k127_6283707_12 713586.KB900536_gene3088 6.325e-79 287.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1WWPS@135613|Chromatiales 135613|Chromatiales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 SYD1_k127_6283707_15 552811.Dehly_0815 8.354e-68 251.0 COG0190@1|root,COG0190@2|Bacteria,2G6BA@200795|Chloroflexi,34CK5@301297|Dehalococcoidia 301297|Dehalococcoidia F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C SYD1_k127_6283707_9 243231.GSU1138 1.433e-95 323.0 COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria,43TFA@69541|Desulfuromonadales 28221|Deltaproteobacteria S YmdB-like protein - - - ko:K09769 - - - - ko00000 - - - YmdB SYD1_k127_6283707_3 1379698.RBG1_1C00001G1123 2.654e-183 587.0 COG1418@1|root,COG1418@2|Bacteria,2NNU5@2323|unclassified Bacteria 2|Bacteria S Endoribonuclease that initiates mRNA decay rny - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 SYD1_k127_6283707_26 1379698.RBG1_1C00001G1122 5.183e-13 75.0 COG3027@1|root,COG3027@2|Bacteria,2NQ5R@2323|unclassified Bacteria 2|Bacteria D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA SYD1_k127_6283707_4 1144275.COCOR_04437 2.291e-152 510.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2YYU4@29|Myxococcales 28221|Deltaproteobacteria J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind SYD1_k127_6283707_8 665956.HMPREF1032_02061 1.038e-104 349.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,3WGWV@541000|Ruminococcaceae 186801|Clostridia J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS - 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d SYD1_k127_6283707_20 429009.Adeg_0536 1.202e-37 145.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,42GJ4@68295|Thermoanaerobacterales 186801|Clostridia J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT - - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 SYD1_k127_6283707_27 1379698.RBG1_1C00001G1117 1.235e-10 72.0 COG0291@1|root,COG0291@2|Bacteria,2NQ3J@2323|unclassified Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p SYD1_k127_6283707_16 1379698.RBG1_1C00001G1116 2.603e-56 205.0 COG0290@1|root,COG0290@2|Bacteria,2NPDH@2323|unclassified Bacteria 2|Bacteria J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N SYD1_k127_6283707_0 1123371.ATXH01000013_gene1505 4.786e-227 721.0 COG0441@1|root,COG0441@2|Bacteria,2GH53@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_SAD SYD1_k127_6283707_23 326427.Cagg_0160 1.268e-27 130.0 COG1807@1|root,COG1807@2|Bacteria,2GAQ1@200795|Chloroflexi,3770G@32061|Chloroflexia 32061|Chloroflexia M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SYD1_k127_6283707_7 880073.Calab_0061 2.707e-123 404.0 COG2876@1|root,COG2876@2|Bacteria,2NNPG@2323|unclassified Bacteria 2|Bacteria E PFAM DAHP synthetase I KDSA ccmA1 - 2.5.1.54 ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 SYD1_k127_6283707_25 932678.THERU_04585 1.507e-16 91.0 COG0491@1|root,COG0491@2|Bacteria 2|Bacteria GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - - - - - - - - - - Lactamase_B SYD1_k127_636425_4 663610.JQKO01000001_gene1025 6.814e-78 265.0 COG1853@1|root,COG1853@2|Bacteria,1NB1B@1224|Proteobacteria,2U5NM@28211|Alphaproteobacteria,3NB22@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct SYD1_k127_636425_7 929562.Emtol_2178 2.803e-44 166.0 COG0454@1|root,COG0454@2|Bacteria,4PKSA@976|Bacteroidetes,47Y1I@768503|Cytophagia 976|Bacteroidetes K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 SYD1_k127_636425_13 468059.AUHA01000005_gene2544 1.838e-08 65.0 2DPXD@1|root,333T1@2|Bacteria,4NZI7@976|Bacteroidetes 976|Bacteroidetes S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 SYD1_k127_636425_5 358220.C380_08910 6.91e-63 219.0 COG1247@1|root,COG1247@2|Bacteria,1RDF5@1224|Proteobacteria,2VT1Y@28216|Betaproteobacteria,4AJYB@80864|Comamonadaceae 28216|Betaproteobacteria M Acetyltransferase (GNAT) family rimI2 - - - - - - - - - - - Acetyltransf_1 SYD1_k127_636425_8 861299.J421_0551 2.706e-37 143.0 2DNQD@1|root,32YJR@2|Bacteria 2|Bacteria S Protein of unknown function (DUF3303) - - - - - - - - - - - - DUF3303 SYD1_k127_636425_11 617140.AJZE01000011_gene2387 6.829e-20 100.0 COG3184@1|root,COG3184@2|Bacteria,1N1QU@1224|Proteobacteria,1T0MS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2059) - - - ko:K09924 - - - - ko00000 - - - DUF2059 SYD1_k127_636425_3 395961.Cyan7425_2945 2.78e-94 319.0 COG2020@1|root,COG2020@2|Bacteria,1G4HN@1117|Cyanobacteria,3KGIV@43988|Cyanothece 1117|Cyanobacteria O Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - 2.1.1.334 ko:K21310 ko00920,map00920 - R11546 RC02653 ko00000,ko00001,ko01000 - - - NnrU,PEMT SYD1_k127_636425_1 1384056.N787_06630 8.798e-122 404.0 COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,1QYHB@1224|Proteobacteria,1T613@1236|Gammaproteobacteria 1236|Gammaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE SYD1_k127_636425_9 1380347.JNII01000006_gene1610 1.042e-34 139.0 COG1917@1|root,COG1917@2|Bacteria,2INQR@201174|Actinobacteria 201174|Actinobacteria S Cupin - - - - - - - - - - - - Cupin_2 SYD1_k127_636425_6 675635.Psed_2048 2.702e-61 218.0 COG1309@1|root,COG1309@2|Bacteria,2IIY2@201174|Actinobacteria,4EAVC@85010|Pseudonocardiales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N SYD1_k127_636425_2 864051.BurJ1DRAFT_2387 1.645e-120 397.0 COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria,2VK7I@28216|Betaproteobacteria,1KNH7@119065|unclassified Burkholderiales 28216|Betaproteobacteria G Phosphoenolpyruvate phosphomutase - - - - - - - - - - - - PEP_mutase SYD1_k127_636425_12 1123253.AUBD01000012_gene986 9.294e-15 85.0 2ATJ5@1|root,31J35@2|Bacteria,1QGTA@1224|Proteobacteria,1TE8Y@1236|Gammaproteobacteria,1X946@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - SYD1_k127_636425_0 1242864.D187_002075 4.624e-151 491.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria 28221|Deltaproteobacteria E PFAM Aminotransferase class I and II - - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 SYD1_k127_6616417_13 326427.Cagg_0443 7.274e-63 230.0 COG1475@1|root,COG1475@2|Bacteria,2G735@200795|Chloroflexi,375G7@32061|Chloroflexia 32061|Chloroflexia K DNA binding - - - - - - - - - - - - DUF4032 SYD1_k127_6616417_1 290397.Adeh_4127 6.15e-202 644.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,43740@68525|delta/epsilon subdivisions,2X1YD@28221|Deltaproteobacteria,2YWVB@29|Myxococcales 28221|Deltaproteobacteria G Alpha-amylase domain - - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase SYD1_k127_6616417_12 215803.DB30_1689 3.108e-73 258.0 COG4945@1|root,COG4945@2|Bacteria,1NYP6@1224|Proteobacteria,4394H@68525|delta/epsilon subdivisions,2X4AK@28221|Deltaproteobacteria,2YYMF@29|Myxococcales 28221|Deltaproteobacteria G C-terminal binding-module, SLH-like, of glucodextranase - - - - - - - - - - - - Glucodextran_C SYD1_k127_6616417_0 215803.DB30_1690 2.765e-296 926.0 2CB5G@1|root,33TBA@2|Bacteria,1NS5Z@1224|Proteobacteria,439KD@68525|delta/epsilon subdivisions,2X4X3@28221|Deltaproteobacteria,2YZSA@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - SYD1_k127_6616417_11 1144275.COCOR_00322 1.689e-99 346.0 COG4945@1|root,COG4945@2|Bacteria,1NQHX@1224|Proteobacteria 1224|Proteobacteria G C-terminal binding-module, SLH-like, of glucodextranase - - - - - - - - - - - - Glucodextran_C SYD1_k127_6616417_7 215803.DB30_1692 2.634e-138 457.0 COG3833@1|root,COG3833@2|Bacteria,1QA3Z@1224|Proteobacteria,42R4X@68525|delta/epsilon subdivisions,2WN1E@28221|Deltaproteobacteria,2YU8W@29|Myxococcales 28221|Deltaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K10110,ko:K15772 ko02010,map02010 M00194,M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22 - - BPD_transp_1 SYD1_k127_6616417_2 378806.STAUR_7140 8.653e-196 631.0 COG1175@1|root,COG1175@2|Bacteria,1MXKR@1224|Proteobacteria,42UM4@68525|delta/epsilon subdivisions,2WQPJ@28221|Deltaproteobacteria,2YUAR@29|Myxococcales 28221|Deltaproteobacteria P Sugar ABC transporter permease malF - - ko:K10109,ko:K15770,ko:K15771 ko02010,map02010 M00194,M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22 - - BPD_transp_1,SBP_bac_8 SYD1_k127_6616417_5 1144275.COCOR_00319 5.242e-177 563.0 COG2182@1|root,COG2182@2|Bacteria,1N9AE@1224|Proteobacteria,43AYA@68525|delta/epsilon subdivisions,2X6CN@28221|Deltaproteobacteria 28221|Deltaproteobacteria G Bacterial extracellular solute-binding protein - - - ko:K15770 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - SBP_bac_1 SYD1_k127_6616417_6 290397.Adeh_4137 4.032e-151 492.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42NVJ@68525|delta/epsilon subdivisions,2WJN1@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Belongs to the ABC transporter superfamily - - 3.6.3.20 ko:K05816,ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00198,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.1.3 - - ABC_tran,TOBE_2 SYD1_k127_6616417_4 1242864.D187_001102 3.767e-192 615.0 COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,42ZYH@68525|delta/epsilon subdivisions,2WVEZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria G Alpha-amylase domain - - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,CBM_20,DUF3459 SYD1_k127_6616417_8 1304874.JAFY01000002_gene747 1.68e-121 400.0 COG1172@1|root,COG1172@2|Bacteria,3TAA3@508458|Synergistetes 508458|Synergistetes G Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 SYD1_k127_6616417_10 1219084.AP014508_gene1118 4.194e-107 357.0 COG1172@1|root,COG1172@2|Bacteria,2GDW6@200918|Thermotogae 200918|Thermotogae U Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 SYD1_k127_6616417_3 1304874.JAFY01000002_gene745 1.419e-193 617.0 COG1129@1|root,COG1129@2|Bacteria,3TA0G@508458|Synergistetes 508458|Synergistetes G PFAM ABC transporter - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran SYD1_k127_6616417_9 688269.Theth_1904 3.83e-109 368.0 COG0683@1|root,COG0683@2|Bacteria,2GDRX@200918|Thermotogae 200918|Thermotogae E Protein of unknown function (DUF3798) - - - - - - - - - - - - DUF3798 SYD1_k127_6616417_16 1356854.N007_15170 3.4e-08 65.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,278RA@186823|Alicyclobacillaceae 91061|Bacilli EGP MFS_1 like family - - - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr SYD1_k127_6616417_15 1379698.RBG1_1C00001G0461 6.149e-26 115.0 COG2143@1|root,COG2143@2|Bacteria 2|Bacteria O COG2143 Thioredoxin-related protein - - - - - - - - - - - - Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7 SYD1_k127_6616417_14 1349767.GJA_455 5.006e-50 186.0 COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2VK6A@28216|Betaproteobacteria,4743P@75682|Oxalobacteraceae 28216|Betaproteobacteria K Bacterial transcriptional repressor C-terminal - - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_C_11,TetR_N SYD1_k127_6661362_1 1379698.RBG1_1C00001G0805 2.227e-170 549.0 COG1012@1|root,COG1012@2|Bacteria,2NNWB@2323|unclassified Bacteria 2|Bacteria C Belongs to the aldehyde dehydrogenase family aldH - 1.2.1.3 ko:K00128,ko:K00138 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh SYD1_k127_6661362_5 767817.Desgi_0471 1.004e-93 317.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,260DQ@186807|Peptococcaceae 186801|Clostridia I PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N SYD1_k127_6661362_0 1089550.ATTH01000001_gene1831 4.382e-175 585.0 COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - NERD,Pkinase,TPR_12,TPR_8 SYD1_k127_6661362_14 1089550.ATTH01000001_gene2237 3.774e-48 179.0 COG1595@1|root,COG1595@2|Bacteria,4NSN4@976|Bacteroidetes 976|Bacteroidetes K ECF sigma factor - - - - - - - - - - - - Sigma70_ECF SYD1_k127_6661362_8 1183438.GKIL_3263 3.88e-73 282.0 COG1470@1|root,COG3391@1|root,COG1470@2|Bacteria,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria 1117|Cyanobacteria DZ PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,VCBS SYD1_k127_6661362_17 1123368.AUIS01000013_gene815 6.036e-34 148.0 COG4313@1|root,COG4313@2|Bacteria,1R5Z9@1224|Proteobacteria,1T97C@1236|Gammaproteobacteria,2NDZP@225057|Acidithiobacillales 225057|Acidithiobacillales C Protein involved in meta-pathway of phenol degradation - - - - - - - - - - - - - SYD1_k127_6661362_13 1123023.JIAI01000003_gene3071 5.403e-53 198.0 COG0702@1|root,COG0702@2|Bacteria,2HC75@201174|Actinobacteria,4E2JF@85010|Pseudonocardiales 201174|Actinobacteria GM NmrA-like family - - - - - - - - - - - - NAD_binding_10,NmrA SYD1_k127_6661362_10 1123242.JH636436_gene344 6.808e-70 250.0 COG5658@1|root,COG5658@2|Bacteria,2J142@203682|Planctomycetes 203682|Planctomycetes S SdpI/YhfL protein family - - - - - - - - - - - - DUF1648,SdpI SYD1_k127_6661362_18 1123242.JH636436_gene345 2.378e-25 108.0 COG0640@1|root,COG0640@2|Bacteria,2J0HF@203682|Planctomycetes 203682|Planctomycetes K regulatory protein, arsR - - - - - - - - - - - - HTH_5 SYD1_k127_6661362_6 926569.ANT_11190 1.393e-91 306.0 COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi 200795|Chloroflexi F Belongs to the dCTP deaminase family dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase SYD1_k127_6661362_2 1379698.RBG1_1C00001G0820 7.581e-153 494.0 COG0621@1|root,COG0621@2|Bacteria,2NNUN@2323|unclassified Bacteria 2|Bacteria J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 SYD1_k127_6661362_7 1379698.RBG1_1C00001G0505 2.43e-74 284.0 COG0308@1|root,COG0308@2|Bacteria,2NPPZ@2323|unclassified Bacteria 2|Bacteria E Peptidase family M1 domain - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 SYD1_k127_6661362_21 1382304.JNIL01000001_gene2578 3.17e-11 65.0 COG3526@1|root,COG3526@2|Bacteria 2|Bacteria O Rdx family - - - ko:K07401 - - - - ko00000 - - - Rdx SYD1_k127_6661362_11 378806.STAUR_1719 5.764e-69 265.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WIYD@28221|Deltaproteobacteria,2YTYJ@29|Myxococcales 28221|Deltaproteobacteria S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C SYD1_k127_6661362_12 1121920.AUAU01000032_gene1522 7.435e-60 228.0 COG0642@1|root,COG2205@2|Bacteria,3Y3IC@57723|Acidobacteria 57723|Acidobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA SYD1_k127_6661362_19 1121423.JONT01000008_gene747 4.673e-21 102.0 COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,261Z3@186807|Peptococcaceae 186801|Clostridia H PFAM Thiamin pyrophosphokinase, vitamin B1 binding domain thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic SYD1_k127_6661362_3 880073.Calab_1151 2.048e-128 443.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec SYD1_k127_6661362_4 880073.Calab_1153 3.448e-96 345.0 COG0591@1|root,COG0591@2|Bacteria,2NRJT@2323|unclassified Bacteria 2|Bacteria E Sodium:solute symporter family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF SYD1_k127_6661362_23 1089553.Tph_c02180 5.422e-07 63.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - PMT_2 SYD1_k127_6661362_9 670487.Ocepr_0866 1.793e-70 249.0 COG0697@1|root,COG0697@2|Bacteria,1WI4X@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus EG PFAM EamA-like transporter family - - - - - - - - - - - - EamA SYD1_k127_6661362_16 1121920.AUAU01000005_gene1059 2.26e-35 143.0 2B9NZ@1|root,3231D@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1579) - - - - - - - - - - - - DUF1579 SYD1_k127_6661362_22 204669.Acid345_2514 1.225e-08 65.0 COG1555@1|root,COG1555@2|Bacteria,3Y5SZ@57723|Acidobacteria,2JK43@204432|Acidobacteriia 204432|Acidobacteriia L Helix-hairpin-helix motif - - - - - - - - - - - - HHH_3 SYD1_k127_6661362_15 118163.Ple7327_2484 4.138e-43 166.0 COG2898@1|root,COG2898@2|Bacteria,1G1E7@1117|Cyanobacteria,3VMFC@52604|Pleurocapsales 1117|Cyanobacteria S Transmembrane region of lysyl-tRNA synthetase - - 2.3.2.3 ko:K07027,ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.3.37,4.D.2 - - DUF2156,tRNA-synt_2_TM SYD1_k127_6694238_22 646529.Desaci_3201 5.954e-14 71.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,260CE@186807|Peptococcaceae 186801|Clostridia F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH,NMO SYD1_k127_6694238_31 35754.JNYJ01000056_gene9920 0.0009183 48.0 COG0835@1|root,COG0835@2|Bacteria,2IPG3@201174|Actinobacteria,4DEJX@85008|Micromonosporales 201174|Actinobacteria NT Two component signalling adaptor domain - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW SYD1_k127_6694238_30 864563.HMPREF9166_1735 0.0001006 55.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H26P@909932|Negativicutes 909932|Negativicutes NT Methyl-accepting chemotaxis protein signaling domain protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 SYD1_k127_6694238_27 378806.STAUR_0871 2.478e-09 70.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WIRT@28221|Deltaproteobacteria,2YTTZ@29|Myxococcales 28221|Deltaproteobacteria T Histidine Phosphotransfer domain cheAY40H-2 - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,HATPase_c,Hpt,Response_reg SYD1_k127_6694238_15 1123386.AUIW01000006_gene1645 7.724e-47 195.0 COG2202@1|root,COG3437@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,1WJ3D@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T PFAM HD domain - - - - - - - - - - - - GAF,GAF_2,HD,HD_5,PAS,PAS_3,PAS_4,PAS_9 SYD1_k127_6694238_14 237368.SCABRO_03992 3.792e-67 261.0 COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,2IWTK@203682|Planctomycetes 203682|Planctomycetes T HD domain - - - - - - - - - - - - GAF_2,HD SYD1_k127_6694238_9 314271.RB2654_06439 2.153e-82 291.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - An_peroxidase,Cadherin,FG-GAP,Glyco_hydro_26,HemolysinCabind,Integrin_beta,Lipase_GDSL_2 SYD1_k127_6694238_28 1121877.JQKF01000025_gene849 6.002e-08 63.0 2ANEH@1|root,31DD4@2|Bacteria,2HGZW@201174|Actinobacteria,4CP03@84992|Acidimicrobiia 84992|Acidimicrobiia - - - - - - - - - - - - - - - SYD1_k127_6694238_11 530564.Psta_3069 2.558e-77 271.0 COG1352@1|root,COG1352@2|Bacteria,2IYFW@203682|Planctomycetes 203682|Planctomycetes NT PFAM MCP methyltransferase CheR-type - - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N SYD1_k127_6694238_6 1246995.AFR_40580 4.794e-97 331.0 COG2201@1|root,COG2201@2|Bacteria,2GMBC@201174|Actinobacteria,4D8WI@85008|Micromonosporales 201174|Actinobacteria NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg SYD1_k127_6694238_18 204669.Acid345_1527 3.436e-32 132.0 COG0745@1|root,COG0745@2|Bacteria,3Y5MN@57723|Acidobacteria,2JJW3@204432|Acidobacteriia 204432|Acidobacteriia T cheY-homologous receiver domain - - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg SYD1_k127_6694238_5 886293.Sinac_3687 2.153e-110 379.0 COG0840@1|root,COG0840@2|Bacteria,2IXQA@203682|Planctomycetes 203682|Planctomycetes NT Methyl-accepting chemotaxis protein (MCP) signaling domain - - - ko:K02660,ko:K03406 ko02020,ko02025,ko02030,map02020,map02025,map02030 - - - ko00000,ko00001,ko02035,ko02044 - - - Globin,HAMP,MCPsignal,PAS_4 SYD1_k127_6694238_19 1123242.JH636434_gene4224 8.569e-27 128.0 COG0835@1|root,COG0835@2|Bacteria,2IZN1@203682|Planctomycetes 203682|Planctomycetes NT CheW domain protein - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW SYD1_k127_6694238_3 1246995.AFR_40595 1.578e-193 629.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,2IBKY@201174|Actinobacteria,4DA7Q@85008|Micromonosporales 201174|Actinobacteria NT Two component signalling adaptor domain cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt SYD1_k127_6694238_23 596153.Alide_2198 7.12e-12 75.0 COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,2VQPE@28216|Betaproteobacteria,4ADGF@80864|Comamonadaceae 28216|Betaproteobacteria K PFAM sigma-70 region 2 domain protein - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SYD1_k127_6694238_25 1379698.RBG1_1C00001G0144 9.183e-11 68.0 2EQQP@1|root,33IAK@2|Bacteria 2|Bacteria S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 SYD1_k127_6694238_16 1379698.RBG1_1C00001G0146 3.094e-46 184.0 COG0356@1|root,COG0356@2|Bacteria,2NPRQ@2323|unclassified Bacteria 2|Bacteria C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A SYD1_k127_6694238_21 1379698.RBG1_1C00001G0147 1.653e-16 81.0 COG0636@1|root,COG0636@2|Bacteria,2NQ21@2323|unclassified Bacteria 2|Bacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C SYD1_k127_6694238_29 1410653.JHVC01000002_gene4202 1.154e-07 60.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,36M51@31979|Clostridiaceae 186801|Clostridia C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iHN637.CLJU_RS01170 ATP-synt_B SYD1_k127_6694238_24 313625.BL107_16705 4.006e-11 74.0 COG0712@1|root,COG0712@2|Bacteria,1G5SS@1117|Cyanobacteria,1GZ6P@1129|Synechococcus 1117|Cyanobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpD GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP SYD1_k127_6694238_0 1379698.RBG1_1C00001G0150 1.622e-242 757.0 COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria 2|Bacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N SYD1_k127_6694238_13 768704.Desmer_4557 1.659e-73 256.0 COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,2601T@186807|Peptococcaceae 186801|Clostridia C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt SYD1_k127_6694238_1 1379698.RBG1_1C00001G0153 1.868e-242 755.0 COG0055@1|root,COG0055@2|Bacteria,2NNRB@2323|unclassified Bacteria 2|Bacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N SYD1_k127_6694238_20 1042163.BRLA_c044310 3.87e-23 104.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,26Y3T@186822|Paenibacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N SYD1_k127_6694238_7 1232410.KI421418_gene2370 3.662e-92 314.0 COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,43S66@69541|Desulfuromonadales 28221|Deltaproteobacteria J Glycoprotease family tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 SYD1_k127_6694238_12 720554.Clocl_0522 1.031e-76 273.0 COG2199@1|root,COG3706@2|Bacteria,1UHZ8@1239|Firmicutes,25E7W@186801|Clostridia,3WGN1@541000|Ruminococcaceae 186801|Clostridia T Diguanylate cyclase, GGDEF domain - - - - - - - - - - - - GGDEF,Response_reg SYD1_k127_6694238_8 1232410.KI421418_gene2385 7.629e-83 311.0 COG0642@1|root,COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2206@2|Bacteria,1NSAV@1224|Proteobacteria,42Z68@68525|delta/epsilon subdivisions,2WURV@28221|Deltaproteobacteria,43U68@69541|Desulfuromonadales 28221|Deltaproteobacteria T Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - - - - - - - - - - GAF_2,HD_5,HisKA SYD1_k127_6694238_10 243231.GSU1939 6.553e-81 301.0 COG0642@1|root,COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2206@2|Bacteria,1NSAV@1224|Proteobacteria,42Z68@68525|delta/epsilon subdivisions,2WURV@28221|Deltaproteobacteria,43U68@69541|Desulfuromonadales 28221|Deltaproteobacteria T Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - - - - - - - - - - GAF_2,HD_5,HisKA SYD1_k127_6694238_17 926561.KB900617_gene1496 8.747e-41 154.0 COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,3WAJ5@53433|Halanaerobiales 186801|Clostridia K PFAM response regulator receiver phoP - - ko:K02483,ko:K07658,ko:K07668 ko02020,map02020 M00434,M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C SYD1_k127_6694238_4 338963.Pcar_0764 2.644e-142 478.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,43RXS@69541|Desulfuromonadales 28221|Deltaproteobacteria L helicase superfamily c-terminal domain priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII SYD1_k127_6694238_26 2880.D7FQJ5 1.927e-09 70.0 COG0457@1|root,KOG1124@2759|Eukaryota 2759|Eukaryota O cellular component assembly - GO:0003008,GO:0007600,GO:0007605,GO:0008150,GO:0032501,GO:0050877,GO:0050954 - ko:K19758 - - - - ko00000,ko04812 - - - CS,TPR_8 SYD1_k127_6694238_2 1379698.RBG1_1C00001G0312 5.776e-215 675.0 COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria 2|Bacteria K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K02887,ko:K03628 ko03010,ko03018,map03010,map03018 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind SYD1_k127_6959500_4 1380350.JIAP01000019_gene14 4.935e-09 59.0 COG3832@1|root,COG3832@2|Bacteria,1R0SY@1224|Proteobacteria,2TYT2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 SYD1_k127_6959500_1 1267534.KB906757_gene883 2.904e-50 184.0 2EHG8@1|root,33B84@2|Bacteria,3Y808@57723|Acidobacteria 57723|Acidobacteria - - - - - - - - - - - - - - - SYD1_k127_6959500_3 1040989.AWZU01000016_gene2427 9.641e-12 70.0 2DBSD@1|root,2ZARI@2|Bacteria,1MX0F@1224|Proteobacteria,2TUNC@28211|Alphaproteobacteria,3JQX7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) MA20_42050 - - - - - - - - - - - GRDB SYD1_k127_6959500_2 706587.Desti_3193 2.466e-36 143.0 2DQBG@1|root,335T7@2|Bacteria,1R35T@1224|Proteobacteria,42ZVK@68525|delta/epsilon subdivisions,2WV6B@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - 1.21.4.1 ko:K10794 ko00330,map00330 - R02825 RC00790 ko00000,ko00001,ko01000 - - - GRDB SYD1_k127_6959500_0 395963.Bind_2963 5.275e-63 220.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria,3NC8C@45404|Beijerinckiaceae 28211|Alphaproteobacteria C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red SYD1_k127_696908_17 880073.Calab_1925 2.526e-11 64.0 COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria 2|Bacteria K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K02887,ko:K03628 ko03010,ko03018,map03010,map03018 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind SYD1_k127_696908_16 1288494.EBAPG3_23510 6.317e-25 106.0 COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2VW5V@28216|Betaproteobacteria,373G1@32003|Nitrosomonadales 28216|Betaproteobacteria J Binds the 23S rRNA rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 SYD1_k127_696908_7 1120985.AUMI01000014_gene717 1.01e-73 258.0 COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,4H271@909932|Negativicutes 909932|Negativicutes S Psort location CytoplasmicMembrane, score 10.00 - - - - - - - - - - - - DUF1385 SYD1_k127_696908_3 667014.Thein_0552 1.271e-121 401.0 COG0216@1|root,COG0216@2|Bacteria,2GHCQ@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 SYD1_k127_696908_12 420324.KI911965_gene785 3.634e-51 204.0 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2TZFK@28211|Alphaproteobacteria,1JSQV@119045|Methylobacteriaceae 28211|Alphaproteobacteria J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_31 SYD1_k127_696908_0 395019.Bmul_0326 1.365e-143 469.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,1K26U@119060|Burkholderiaceae 28216|Betaproteobacteria M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase SYD1_k127_696908_1 671143.DAMO_0088 2.088e-142 478.0 COG3276@1|root,COG3276@2|Bacteria,2NNQU@2323|unclassified Bacteria 2|Bacteria J Elongation factor SelB, winged helix selB - - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 SYD1_k127_696908_8 335543.Sfum_1010 3.215e-64 248.0 COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria,2MR79@213462|Syntrophobacterales 28221|Deltaproteobacteria KT Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - ko:K02584 ko02020,map02020 - - - ko00000,ko00001,ko03000 - - - GAF,GAF_2,HTH_8,Sigma54_activat SYD1_k127_696908_14 292459.STH1332 1.032e-36 162.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia 186801|Clostridia K Fibronectin-binding protein FbpA - - - - - - - - - - - DUF814,FbpA SYD1_k127_696908_15 439235.Dalk_5269 7.207e-29 134.0 COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1R09K@1224|Proteobacteria 1224|Proteobacteria M Tetratricopeptide repeat - - - - - - - - - - - - TPR_11,TPR_2 SYD1_k127_696908_9 518766.Rmar_0011 1.947e-62 226.0 COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,1FJ8A@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Domain of unknown function (DUF1732) - - - - - - - - - - - - DUF1732,YicC_N SYD1_k127_696908_11 373903.Hore_09810 3.199e-51 189.0 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,3WAPB@53433|Halanaerobiales 186801|Clostridia F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin SYD1_k127_696908_4 1408254.T458_17280 7.362e-93 320.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,26R8P@186822|Paenibacillaceae 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein SYD1_k127_696908_10 316067.Geob_3525 1.05e-60 219.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,43TTD@69541|Desulfuromonadales 28221|Deltaproteobacteria L Uracil DNA glycosylase superfamily - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG SYD1_k127_696908_2 243231.GSU0998 2.536e-141 467.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,43SXC@69541|Desulfuromonadales 28221|Deltaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C SYD1_k127_696908_6 1379698.RBG1_1C00001G0978 2.36e-74 258.0 COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria 2|Bacteria Q ABC-type transport system involved in resistance to organic solvents permease component - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE SYD1_k127_696908_5 1379698.RBG1_1C00001G0979 9.669e-86 291.0 COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria 2|Bacteria Q ABC-type transport system involved in resistance to organic solvents, ATPase component mkl - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran SYD1_k127_696908_13 1379698.RBG1_1C00001G0556 3.646e-43 171.0 COG1463@1|root,COG1463@2|Bacteria,2NPXB@2323|unclassified Bacteria 2|Bacteria Q MlaD protein ttg2C - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD SYD1_k127_6997799_10 204669.Acid345_0280 2.843e-177 571.0 COG0574@1|root,COG0784@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria,3Y7G5@57723|Acidobacteria 57723|Acidobacteria G Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - - - - - - - - - - PPDK_N SYD1_k127_6997799_4 204669.Acid345_0942 4.408e-252 784.0 COG0334@1|root,COG0334@2|Bacteria,3Y3B4@57723|Acidobacteria,2JI4Q@204432|Acidobacteriia 2|Bacteria E Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N SYD1_k127_6997799_70 330214.NIDE3769 1.038e-39 167.0 COG0529@1|root,COG0529@2|Bacteria 2|Bacteria P adenylylsulfate kinase activity cysC - 2.7.1.25,2.7.7.4 ko:K00860,ko:K00955 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase SYD1_k127_6997799_37 330214.NIDE3770 3.001e-103 360.0 COG3173@1|root,COG3173@2|Bacteria 2|Bacteria S very-long-chain-acyl-CoA dehydrogenase activity - - - - - - - - - - - - APH SYD1_k127_6997799_48 1123393.KB891326_gene82 5.323e-83 288.0 COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,2VIGZ@28216|Betaproteobacteria,1KTA6@119069|Hydrogenophilales 119069|Hydrogenophilales M Bacterial capsule synthesis protein PGA_cap - - - ko:K07282 - - - - ko00000 - - - PGA_cap SYD1_k127_6997799_84 420324.KI912066_gene6595 3.41e-19 103.0 COG0517@1|root,COG0517@2|Bacteria,1NMH1@1224|Proteobacteria,2U9D8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S CBS domain - - - - - - - - - - - - CBS SYD1_k127_6997799_7 1379698.RBG1_1C00001G0700 2.169e-217 683.0 COG0427@1|root,COG0427@2|Bacteria,2NQDP@2323|unclassified Bacteria 2|Bacteria C Acetyl-CoA hydrolase/transferase N-terminal domain - - 3.1.2.1 ko:K01067 ko00620,map00620 - R00227 RC00004,RC00012 ko00000,ko00001,ko01000 - - - AcetylCoA_hyd_C,AcetylCoA_hydro SYD1_k127_6997799_13 1379698.RBG1_1C00001G0699 1.627e-161 519.0 COG0686@1|root,COG0686@2|Bacteria,2NP43@2323|unclassified Bacteria 2|Bacteria E Alanine dehydrogenase/PNT, C-terminal domain ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N SYD1_k127_6997799_0 1379698.RBG1_1C00001G0698 0.0 1104.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,2NNV3@2323|unclassified Bacteria 2|Bacteria C Malic enzyme, NAD binding domain maeB GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 ko:K00027,ko:K00029,ko:K00625,ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02020,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200,map02020 M00169,M00172,M00357,M00579 R00214,R00216,R00230,R00921 RC00004,RC00105,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1637 Malic_M,PTA_PTB,malic SYD1_k127_6997799_57 404589.Anae109_3408 1.066e-72 272.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YUYF@29|Myxococcales 28221|Deltaproteobacteria T Histidine kinase ntrY - 2.7.13.3 ko:K13598 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 SYD1_k127_6997799_26 1125863.JAFN01000001_gene1650 6.171e-123 423.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria 28221|Deltaproteobacteria T two component, sigma54 specific, transcriptional regulator, Fis family ntrX - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_6997799_30 204669.Acid345_4390 1.128e-116 411.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y69R@57723|Acidobacteria,2JKIQ@204432|Acidobacteriia 204432|Acidobacteriia KLT Protein kinase domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase SYD1_k127_6997799_63 398767.Glov_2398 1.799e-56 218.0 COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42R04@68525|delta/epsilon subdivisions,2WMZ2@28221|Deltaproteobacteria 28221|Deltaproteobacteria I PFAM ATPase, BadF BadG BcrA BcrD type - - - - - - - - - - - - BcrAD_BadFG SYD1_k127_6997799_45 398767.Glov_2399 1.969e-89 316.0 COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,43V8M@69541|Desulfuromonadales 28221|Deltaproteobacteria I BadF/BadG/BcrA/BcrD ATPase family yjiL - - - - - - - - - - - BcrAD_BadFG SYD1_k127_6997799_29 398767.Glov_2400 1.527e-117 409.0 COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,430HE@68525|delta/epsilon subdivisions,2WVZI@28221|Deltaproteobacteria,43V4N@69541|Desulfuromonadales 28221|Deltaproteobacteria E 2-hydroxyglutaryl-CoA dehydratase, D-component - - 1.3.7.8 ko:K04113 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D SYD1_k127_6997799_33 398767.Glov_2401 5.277e-114 391.0 COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria,43V0Q@69541|Desulfuromonadales 28221|Deltaproteobacteria E 2-hydroxyglutaryl-CoA dehydratase, D-component - - 1.3.7.8 ko:K04112 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D SYD1_k127_6997799_69 1125863.JAFN01000001_gene2446 7.604e-41 169.0 COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,42NZQ@68525|delta/epsilon subdivisions,2WMCW@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Enoyl-CoA hydratase/isomerase - - 4.2.1.100 ko:K07537 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05597 RC03168 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 SYD1_k127_6997799_60 269799.Gmet_2059 2.698e-67 240.0 COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,42QAM@68525|delta/epsilon subdivisions,2WM04@28221|Deltaproteobacteria 28221|Deltaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100,1.1.1.36 ko:K00023,ko:K00059 ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212 M00083,M00373,M00572 R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00103,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SYD1_k127_6997799_16 1187851.A33M_3194 3.413e-148 479.0 COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,2U4PY@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Enoyl-CoA hydratase/isomerase - - 3.7.1.21 ko:K07539 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05593,R05594,R10696 RC01430,RC01431,RC03237 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 SYD1_k127_6997799_25 1187851.A33M_3193 2.265e-124 410.0 COG1063@1|root,COG1063@2|Bacteria,1QTU5@1224|Proteobacteria,2TW9Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology yphC - 1.1.1.368 ko:K07538 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05581 RC00850 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_N_assoc,ADH_zinc_N SYD1_k127_6997799_79 644966.Tmar_0475 1.737e-30 129.0 COG1309@1|root,COG1309@2|Bacteria,1V3QD@1239|Firmicutes,25BU1@186801|Clostridia,3WDJR@538999|Clostridiales incertae sedis 186801|Clostridia K PFAM Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N SYD1_k127_6997799_15 404589.Anae109_1775 1.201e-158 522.0 COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,42ZD0@68525|delta/epsilon subdivisions,2WU4P@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation aceK - 2.7.11.5 ko:K00906 - - - - ko00000,ko01000 - - - AceK SYD1_k127_6997799_6 404589.Anae109_2186 7.011e-218 695.0 COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,42M56@68525|delta/epsilon subdivisions,2WJ8W@28221|Deltaproteobacteria,2YYDJ@29|Myxococcales 28221|Deltaproteobacteria C Isocitrate/isopropylmalate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh SYD1_k127_6997799_8 926569.ANT_19690 5.892e-204 643.0 COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi 200795|Chloroflexi E PFAM peptidase M20 - - - - - - - - - - - - M20_dimer,Peptidase_M20 SYD1_k127_6997799_12 1278073.MYSTI_03755 3.121e-165 533.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YUB5@29|Myxococcales 28221|Deltaproteobacteria T response regulator - - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_6997799_41 502025.Hoch_3223 1.693e-93 321.0 COG0642@1|root,COG0642@2|Bacteria,1QX5P@1224|Proteobacteria,43BYA@68525|delta/epsilon subdivisions,2X796@28221|Deltaproteobacteria,2Z3E9@29|Myxococcales 28221|Deltaproteobacteria T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K07709 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA SYD1_k127_6997799_39 518766.Rmar_0066 3.611e-96 332.0 COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1FJ0W@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes MU Outer membrane efflux protein - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP SYD1_k127_6997799_17 1379270.AUXF01000001_gene1951 1.831e-142 477.0 COG0577@1|root,COG0577@2|Bacteria,1ZSUJ@142182|Gemmatimonadetes 142182|Gemmatimonadetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SYD1_k127_6997799_73 1379270.AUXF01000001_gene1950 4.145e-33 130.0 COG1136@1|root,COG1136@2|Bacteria,1ZUSK@142182|Gemmatimonadetes 142182|Gemmatimonadetes V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SYD1_k127_6997799_65 1379270.AUXF01000001_gene1950 2.755e-51 202.0 COG1136@1|root,COG1136@2|Bacteria,1ZUSK@142182|Gemmatimonadetes 142182|Gemmatimonadetes V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SYD1_k127_6997799_36 379066.GAU_0845 3.125e-109 370.0 COG0845@1|root,COG0845@2|Bacteria,1ZU07@142182|Gemmatimonadetes 142182|Gemmatimonadetes M Biotin-lipoyl like - - - ko:K02005 - - - - ko00000 - - - HlyD_D23 SYD1_k127_6997799_68 1245471.PCA10_41000 1.56e-43 168.0 COG2020@1|root,COG2020@2|Bacteria,1MUBZ@1224|Proteobacteria,1RREG@1236|Gammaproteobacteria,1YH7J@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria O Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - - - - - - - - - - ICMT,PEMT SYD1_k127_6997799_75 925409.KI911562_gene1750 3.176e-32 141.0 COG1730@1|root,COG1730@2|Bacteria,4PAM0@976|Bacteroidetes,1IW3E@117747|Sphingobacteriia 976|Bacteroidetes O unfolded protein binding - - - - - - - - - - - - - SYD1_k127_6997799_46 926556.Echvi_4122 2.113e-87 305.0 COG3488@1|root,COG3488@2|Bacteria,4NGBS@976|Bacteroidetes,47ND9@768503|Cytophagia 976|Bacteroidetes C Di-haem oxidoreductase, putative peroxidase - - - - - - - - - - - - DHOR SYD1_k127_6997799_23 469383.Cwoe_4029 2.519e-126 411.0 COG2230@1|root,COG2230@2|Bacteria 2|Bacteria M cyclopropane-fatty-acyl-phospholipid synthase cfa1 - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS SYD1_k127_6997799_56 926560.KE387027_gene263 1.727e-73 272.0 COG2120@1|root,COG2120@2|Bacteria 2|Bacteria S N-acetylglucosaminylinositol deacetylase activity - - - ko:K22135 - - - - ko00000,ko01000 - - - PIG-L SYD1_k127_6997799_1 215803.DB30_2650 1.498e-296 920.0 COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,42PRT@68525|delta/epsilon subdivisions,2WIWH@28221|Deltaproteobacteria,2YU1K@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle pckG - 4.1.1.32 ko:K01596 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003 R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2638 PEPCK_C,PEPCK_N SYD1_k127_6997799_9 762376.AXYL_03828 6.795e-192 615.0 COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2VI8J@28216|Betaproteobacteria 28216|Betaproteobacteria C PFAM FAD linked oxidase domain protein - - - - - - - - - - - - BBE,FAD_binding_4 SYD1_k127_6997799_72 1121403.AUCV01000002_gene474 3.666e-37 145.0 COG4747@1|root,COG4747@2|Bacteria 2|Bacteria - - hom - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 ko:K00003,ko:K00058,ko:K01754,ko:K04767 ko00260,ko00270,ko00290,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00290,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00017,M00018,M00020,M00570 R00220,R00996,R01513,R01773,R01775 RC00031,RC00087,RC00418,RC02600 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT,CBS,Homoserine_dh,Lactamase_B,NAD_binding_3 SYD1_k127_6997799_27 497964.CfE428DRAFT_1990 4.332e-120 398.0 COG0665@1|root,COG0665@2|Bacteria,46TXP@74201|Verrucomicrobia 74201|Verrucomicrobia E FAD dependent oxidoreductase - - - - - - - - - - - - DAO SYD1_k127_6997799_61 1121013.P873_08950 1.04e-66 249.0 COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,1RN0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Amidinotransferase - - 3.5.3.18 ko:K01482 - - - - ko00000,ko01000,ko04147 - - - Amidinotransf SYD1_k127_6997799_20 926560.KE387023_gene2306 5.349e-134 462.0 COG0520@1|root,COG0520@2|Bacteria 2|Bacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine cefD - 5.1.1.17 ko:K04127,ko:K11325,ko:K21174 ko00311,ko01059,ko01100,ko01130,map00311,map01059,map01100,map01130 M00673,M00825 R04147 RC00302 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 SYD1_k127_6997799_24 290318.Cvib_1268 2.561e-125 422.0 COG1966@1|root,COG1966@2|Bacteria 2|Bacteria T Carbon starvation protein - - - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM SYD1_k127_6997799_2 1128421.JAGA01000004_gene2674 7.719e-273 847.0 COG0366@1|root,COG0366@2|Bacteria,2NQND@2323|unclassified Bacteria 2|Bacteria G Maltogenic Amylase, C-terminal domain treS - 3.2.1.1,5.4.99.16 ko:K05343 ko00500,ko01100,map00500,map01100 - R01557,R02108,R02112,R11262 RC01816 ko00000,ko00001,ko01000 - GH13 - APH,Alpha-amylase,Malt_amylase_C SYD1_k127_6997799_47 671143.DAMO_1539 4.646e-85 298.0 COG0463@1|root,COG0463@2|Bacteria,2NQD9@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferase family 2 - - 2.4.1.268 ko:K21349 - - - - ko00000,ko01000 - GT81 - Glycos_transf_2 SYD1_k127_6997799_74 215803.DB30_6917 1.607e-32 134.0 COG1309@1|root,COG1309@2|Bacteria,1N6R3@1224|Proteobacteria,42N4M@68525|delta/epsilon subdivisions,2X9VB@28221|Deltaproteobacteria,2Z105@29|Myxococcales 28221|Deltaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N SYD1_k127_6997799_54 861299.J421_2436 2.969e-75 266.0 COG1566@1|root,COG1566@2|Bacteria,1ZT4J@142182|Gemmatimonadetes 142182|Gemmatimonadetes V Biotin-lipoyl like - - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3 SYD1_k127_6997799_11 1304885.AUEY01000021_gene3455 3.207e-167 552.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,42KZU@68525|delta/epsilon subdivisions,2WJ6T@28221|Deltaproteobacteria,2MIX6@213118|Desulfobacterales 28221|Deltaproteobacteria EGP Sugar (and other) transporter - - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 SYD1_k127_6997799_42 1242864.D187_006013 4.589e-93 313.0 COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria 1224|Proteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short SYD1_k127_6997799_50 926569.ANT_21960 7.555e-81 300.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5NN@200795|Chloroflexi 200795|Chloroflexi E Peptidase S9, prolyl oligopeptidase active site domain protein - - - - - - - - - - - - PD40,Peptidase_S9 SYD1_k127_6997799_18 1144275.COCOR_07436 7.628e-139 452.0 COG3239@1|root,COG3239@2|Bacteria,1QKDT@1224|Proteobacteria 1224|Proteobacteria I fatty acid desaturase - - 1.14.19.3 ko:K00508 ko00591,ko01100,map00591,map01100 - R07063 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase SYD1_k127_6997799_62 1381123.AYOD01000006_gene1134 1.632e-64 245.0 COG0513@1|root,COG1118@1|root,COG0513@2|Bacteria,COG1118@2|Bacteria,1MU49@1224|Proteobacteria,2TST2@28211|Alphaproteobacteria,43HV9@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L Belongs to the DEAD box helicase family deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C SYD1_k127_6997799_89 1380390.JIAT01000010_gene4655 6.967e-08 65.0 COG4149@1|root,COG4149@2|Bacteria,2GJFB@201174|Actinobacteria,4CU4B@84995|Rubrobacteria 84995|Rubrobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 SYD1_k127_6997799_78 644076.SCH4B_3568 4.943e-31 136.0 COG0555@1|root,COG0555@2|Bacteria,1NQQ5@1224|Proteobacteria,2TQUP@28211|Alphaproteobacteria 28211|Alphaproteobacteria O binding-protein-dependent transport systems inner membrane component - - - ko:K02053 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 SYD1_k127_6997799_51 1042375.AFPL01000038_gene1559 2.173e-80 287.0 COG1840@1|root,COG1840@2|Bacteria,1Q13Q@1224|Proteobacteria,1RWV9@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC transporter substrate-binding protein - - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_6 SYD1_k127_6997799_21 404589.Anae109_0507 7.248e-133 438.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria 1224|Proteobacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase SYD1_k127_6997799_59 1521187.JPIM01000004_gene3035 8.198e-68 259.0 COG1013@1|root,COG1013@2|Bacteria,2G679@200795|Chloroflexi,374ZH@32061|Chloroflexia 32061|Chloroflexia C PFAM thiamine pyrophosphate protein domain protein TPP-binding - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFO_beta_C,TPP_enzyme_C SYD1_k127_6997799_35 670487.Ocepr_1225 1.666e-109 386.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1WIAF@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C COGs COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase alpha subunit - - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - POR,POR_N SYD1_k127_6997799_38 765912.Thimo_0229 4.845e-100 337.0 COG1142@1|root,COG2878@1|root,COG1142@2|Bacteria,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,1RPC4@1236|Gammaproteobacteria,1WWC5@135613|Chromatiales 135613|Chromatiales C Fe-S cluster - - - ko:K03616 - - - - ko00000 - - - FeS,Fer4 SYD1_k127_6997799_53 765912.Thimo_0230 9.036e-76 266.0 COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1WX8K@135613|Chromatiales 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfA - - ko:K03617 - - - - ko00000 - - - Rnf-Nqr SYD1_k127_6997799_55 765912.Thimo_0231 4.727e-74 256.0 COG4660@1|root,COG4660@2|Bacteria,1R342@1224|Proteobacteria,1T62W@1236|Gammaproteobacteria,1WW5Q@135613|Chromatiales 135613|Chromatiales U Part of a membrane complex involved in electron transport - - - ko:K03613 - - - - ko00000 - - - Rnf-Nqr SYD1_k127_6997799_71 765912.Thimo_0232 7.406e-38 162.0 COG4659@1|root,COG4659@2|Bacteria,1R98X@1224|Proteobacteria 1224|Proteobacteria C Part of a membrane complex involved in electron transport - - - ko:K03612 - - - - ko00000 - - - FMN_bind SYD1_k127_6997799_44 765912.Thimo_0233 1.091e-91 329.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1T20Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrB - 1.6.5.8 ko:K00347,ko:K03614 - - - - ko00000,ko01000 - - - NQR2_RnfD_RnfE SYD1_k127_6997799_32 706587.Desti_2902 6.713e-115 398.0 COG4656@1|root,COG4656@2|Bacteria,1PJE1@1224|Proteobacteria,42P69@68525|delta/epsilon subdivisions,2WIM9@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily - - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB SYD1_k127_6997799_67 706587.Desti_5049 1.352e-43 173.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria,2MS09@213462|Syntrophobacterales 28221|Deltaproteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE SYD1_k127_6997799_92 690850.Desaf_1051 0.0005064 46.0 COG1141@1|root,COG1141@2|Bacteria 2|Bacteria C electron transfer activity fer - - ko:K05337 - - - - ko00000 - - - Fer4_13 SYD1_k127_6997799_88 247490.KSU1_D0950 1.506e-09 70.0 COG1014@1|root,COG1144@1|root,COG1014@2|Bacteria,COG1144@2|Bacteria 2|Bacteria C oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor porD - 1.2.1.58,1.2.7.1 ko:K00171,ko:K00172,ko:K18357,ko:K18358 ko00010,ko00020,ko00360,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00360,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R02450,R08034 RC00004,RC00250,RC02742,RC02833,RC02860 br01601,ko00000,ko00001,ko00002,ko01000 - - - Fer4,Fer4_21,POR SYD1_k127_6997799_83 416591.Tlet_1775 9.632e-23 115.0 COG0674@1|root,COG0674@2|Bacteria,2GC9T@200918|Thermotogae 200918|Thermotogae C Pyruvate flavodoxin ferredoxin oxidoreductase domain protein - GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 ko:K00169,ko:K03737 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034,R10866 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C SYD1_k127_6997799_81 1235793.C809_03566 9.36e-28 131.0 COG1013@1|root,COG1013@2|Bacteria,1TPF0@1239|Firmicutes,24BE5@186801|Clostridia,27JHQ@186928|unclassified Lachnospiraceae 186801|Clostridia C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain porB - 1.2.7.1 ko:K00170 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C SYD1_k127_6997799_22 452637.Oter_4084 1.755e-127 439.0 COG0006@1|root,COG0006@2|Bacteria,46U30@74201|Verrucomicrobia 74201|Verrucomicrobia E Aminopeptidase P, N-terminal domain - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 SYD1_k127_6997799_66 1356852.N008_16470 1.433e-49 183.0 COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,47PR7@768503|Cytophagia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 SYD1_k127_6997799_28 452637.Oter_0943 1.92e-119 415.0 COG0513@1|root,COG0513@2|Bacteria,46S5M@74201|Verrucomicrobia,3K7N6@414999|Opitutae 414999|Opitutae L helicase superfamily c-terminal domain - - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C SYD1_k127_6997799_34 240015.ACP_2205 3.57e-113 373.0 COG0010@1|root,COG0010@2|Bacteria,3Y46E@57723|Acidobacteria,2JIPY@204432|Acidobacteriia 204432|Acidobacteriia E Arginase family - - 3.5.3.1 ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00134 R00551 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase SYD1_k127_6997799_80 1123267.JONN01000001_gene1239 2.617e-29 138.0 2C1YS@1|root,2ZD2Y@2|Bacteria 2|Bacteria S Protease prsW family - - - - - - - - - - - - PrsW-protease SYD1_k127_6997799_3 1123267.JONN01000001_gene1238 2.744e-258 829.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - Cupin_2,MRJP SYD1_k127_6997799_76 383372.Rcas_2068 5.607e-32 133.0 COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi,375JF@32061|Chloroflexia 32061|Chloroflexia K PFAM sigma-70 region 2 domain protein - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SYD1_k127_6997799_90 1237149.C900_03127 1.318e-07 62.0 COG1366@1|root,COG1366@2|Bacteria,4NVHQ@976|Bacteroidetes,47RVX@768503|Cytophagia 976|Bacteroidetes T Belongs to the anti-sigma-factor antagonist family - - - ko:K04749 - - - - ko00000,ko03021 - - - STAS SYD1_k127_6997799_85 573370.DMR_19130 1.396e-14 79.0 COG2172@1|root,COG2172@2|Bacteria,1N9RD@1224|Proteobacteria,42V4M@68525|delta/epsilon subdivisions,2WRKJ@28221|Deltaproteobacteria,2MBIZ@213115|Desulfovibrionales 28221|Deltaproteobacteria T anti-sigma regulatory factor, serine threonine protein kinase - - 2.7.11.1 ko:K04757 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c_2 SYD1_k127_6997799_87 880073.Calab_0921 1.454e-10 75.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - DUF4157,FctA,Peptidase_M43 SYD1_k127_6997799_86 1121918.ARWE01000001_gene1797 4.421e-13 83.0 COG1404@1|root,COG1404@2|Bacteria,1QYWU@1224|Proteobacteria,42VXP@68525|delta/epsilon subdivisions,2X7PK@28221|Deltaproteobacteria 28221|Deltaproteobacteria O PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - - SYD1_k127_6997799_14 1157943.KB892705_gene2336 2.341e-160 545.0 COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae 201174|Actinobacteria K involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein pknK_2 - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - AAA_22,GerE,NB-ARC,Pkinase,TPR_12 SYD1_k127_6997799_5 760568.Desku_1070 5.079e-222 717.0 COG1067@1|root,COG1067@2|Bacteria,1TQT5@1239|Firmicutes,248NE@186801|Clostridia,260R2@186807|Peptococcaceae 186801|Clostridia O Belongs to the peptidase S16 family - - - - - - - - - - - - AAA_32,Lon_C SYD1_k127_6997799_43 62928.azo0832 2.751e-92 336.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VKXU@28216|Betaproteobacteria,2KVSV@206389|Rhodocyclales 206389|Rhodocyclales V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SYD1_k127_6997799_40 497321.C664_19291 3.301e-94 332.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VIIH@28216|Betaproteobacteria,2KU75@206389|Rhodocyclales 206389|Rhodocyclales V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SYD1_k127_6997799_49 686340.Metal_3602 2.348e-82 280.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1XDVV@135618|Methylococcales 135618|Methylococcales V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SYD1_k127_6997799_64 395494.Galf_2064 9.94e-53 203.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria,44V3R@713636|Nitrosomonadales 28216|Betaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - HlyD_D23 SYD1_k127_6997799_77 757424.Hsero_0372 1.717e-31 126.0 COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,2VSPC@28216|Betaproteobacteria,474Q9@75682|Oxalobacteraceae 28216|Betaproteobacteria B SWI complex, BAF60b domains - - - - - - - - - - - - SWIB SYD1_k127_6997799_91 1347086.CCBA010000012_gene2030 0.000158 44.0 2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - SYD1_k127_6997799_31 517418.Ctha_1672 1.888e-116 394.0 COG0297@1|root,COG0297@2|Bacteria,1FDT0@1090|Chlorobi 1090|Chlorobi F Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 SYD1_k127_6997799_19 880072.Desac_2413 3.918e-136 442.0 COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2WKT8@28221|Deltaproteobacteria,2MR4U@213462|Syntrophobacterales 28221|Deltaproteobacteria C Domain of unknown function (DUF4921) galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - DUF4921,GalP_UDP_tr_C,GalP_UDP_transf SYD1_k127_6997799_52 1242864.D187_001368 9.537e-78 272.0 COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,2YUTZ@29|Myxococcales 28221|Deltaproteobacteria M Mannose-6-phosphate isomerase manAC - 2.7.7.13 ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885 RC00002 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase SYD1_k127_6997799_58 290397.Adeh_2455 1.445e-68 238.0 COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Sugar transferase - - - - - - - - - - - - Bac_transf,CoA_binding_3 SYD1_k127_6997799_82 1198114.AciX9_2489 1.353e-23 115.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity wcoG - - - - - - - - - - - DUF5122,Laminin_G_3,PKD SYD1_k127_7051182_20 909663.KI867150_gene1296 1.791e-17 81.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2MQ8F@213462|Syntrophobacterales 28221|Deltaproteobacteria J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 SYD1_k127_7051182_10 1121428.DESHY_150041___1 1.337e-44 163.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,2620M@186807|Peptococcaceae 186801|Clostridia J Involved in the binding of tRNA to the ribosomes rpsJ - - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 SYD1_k127_7051182_4 96561.Dole_0708 3.95e-65 230.0 COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2WNJ1@28221|Deltaproteobacteria,2MJKX@213118|Desulfobacterales 28221|Deltaproteobacteria J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 SYD1_k127_7051182_9 1506994.JNLQ01000002_gene1002 6.633e-46 173.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,4BX2C@830|Butyrivibrio 186801|Clostridia J Forms part of the polypeptide exit tunnel rplD - - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 SYD1_k127_7051182_19 671143.DAMO_0541 1.89e-25 117.0 COG0089@1|root,COG0089@2|Bacteria,2NPWC@2323|unclassified Bacteria 2|Bacteria J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 SYD1_k127_7051182_1 1121456.ATVA01000011_gene1622 8.284e-114 372.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,42MBV@68525|delta/epsilon subdivisions,2WIRE@28221|Deltaproteobacteria,2M8B7@213115|Desulfovibrionales 28221|Deltaproteobacteria J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C SYD1_k127_7051182_12 1382359.JIAL01000001_gene1700 9.389e-38 143.0 COG0185@1|root,COG0185@2|Bacteria,3Y560@57723|Acidobacteria,2JJMI@204432|Acidobacteriia 204432|Acidobacteriia J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS - - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 SYD1_k127_7051182_15 350688.Clos_0497 6.545e-28 122.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,36JMN@31979|Clostridiaceae 186801|Clostridia J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV - - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 SYD1_k127_7051182_2 1333998.M2A_2923 1.172e-79 271.0 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2TRZ2@28211|Alphaproteobacteria,4BPQ4@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C SYD1_k127_7051182_5 635013.TherJR_0303 8.845e-65 223.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,261KH@186807|Peptococcaceae 186801|Clostridia J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP - - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 SYD1_k127_7051182_22 926561.KB900620_gene3193 1.073e-08 60.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3WAX4@53433|Halanaerobiales 186801|Clostridia J Belongs to the universal ribosomal protein uL29 family rpmC - - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 SYD1_k127_7051182_17 857293.CAAU_1218 6.134e-26 110.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,36KIV@31979|Clostridiaceae 186801|Clostridia J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ - - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 SYD1_k127_7051182_8 762903.Pedsa_2138 4.981e-48 175.0 COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,1ISEA@117747|Sphingobacteriia 976|Bacteroidetes J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 SYD1_k127_7051182_16 96561.Dole_0719 2.266e-27 120.0 COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,42TGC@68525|delta/epsilon subdivisions,2WQ2G@28221|Deltaproteobacteria,2MKGD@213118|Desulfobacterales 28221|Deltaproteobacteria J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 SYD1_k127_7051182_3 1379698.RBG1_1C00001G1584 1.011e-76 263.0 COG0094@1|root,COG0094@2|Bacteria,2NP65@2323|unclassified Bacteria 2|Bacteria J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C SYD1_k127_7051182_18 660470.Theba_0690 7.414e-26 107.0 COG0199@1|root,COG0199@2|Bacteria,2GDFE@200918|Thermotogae 200918|Thermotogae J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 SYD1_k127_7051182_11 457570.Nther_0208 7.067e-44 163.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia 186801|Clostridia J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH - - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 SYD1_k127_7051182_7 926567.TheveDRAFT_0595 1.268e-59 211.0 COG0097@1|root,COG0097@2|Bacteria,3TAW4@508458|Synergistetes 508458|Synergistetes J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF - - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 SYD1_k127_7051182_14 246194.CHY_2293 5.312e-34 134.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,42GIE@68295|Thermoanaerobacterales 186801|Clostridia J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR - - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p SYD1_k127_7051182_6 264732.Moth_2443 3.053e-64 225.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,42G80@68295|Thermoanaerobacterales 186801|Clostridia J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE - - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C SYD1_k127_7051182_21 266117.Rxyl_2137 5.886e-13 72.0 COG1841@1|root,COG1841@2|Bacteria 2|Bacteria J maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rpmD GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 SYD1_k127_7051182_13 880073.Calab_2145 1.142e-35 141.0 COG0200@1|root,COG0200@2|Bacteria,2NPNV@2323|unclassified Bacteria 2|Bacteria J Binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A SYD1_k127_7051182_0 1379698.RBG1_1C00001G1576 5.464e-167 543.0 COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria 2|Bacteria U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY SYD1_k127_7135859_3 105559.Nwat_0061 3.424e-32 136.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1WWP3@135613|Chromatiales 135613|Chromatiales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase SYD1_k127_7135859_2 582515.KR51_00010680 7.518e-90 312.0 COG0282@1|root,COG0282@2|Bacteria,1G214@1117|Cyanobacteria 1117|Cyanobacteria F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase SYD1_k127_7135859_0 103733.JNYO01000005_gene8568 2.775e-287 904.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4E0YN@85010|Pseudonocardiales 201174|Actinobacteria G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase - - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N SYD1_k127_7311309_67 255470.cbdbA943 7.102e-17 80.0 COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,34CJX@301297|Dehalococcoidia 301297|Dehalococcoidia I Myo-inositol-1-phosphate synthase - - 5.5.1.4 ko:K01858 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 - R07324 RC01804 ko00000,ko00001,ko01000 - - - Inos-1-P_synth SYD1_k127_7311309_55 1122182.KB903825_gene320 2.301e-30 137.0 COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4DCRP@85008|Micromonosporales 201174|Actinobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA1 GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.11,2.7.8.5 ko:K00995,ko:K00999 ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070 - R01801,R01802 RC00002,RC00017,RC00078,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf SYD1_k127_7311309_26 1121468.AUBR01000004_gene158 2.513e-70 260.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,42F0X@68295|Thermoanaerobacterales 186801|Clostridia H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase SYD1_k127_7311309_21 1278073.MYSTI_01452 7.114e-88 304.0 COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria,2YUBW@29|Myxococcales 28221|Deltaproteobacteria E Threonine aldolase ltaA - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase SYD1_k127_7311309_29 1286171.EAL2_c14710 2.642e-66 233.0 COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia,25VGF@186806|Eubacteriaceae 186801|Clostridia S neutral zinc metallopeptidase yugP - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 SYD1_k127_7311309_57 1379698.RBG1_1C00001G1143 2.962e-29 120.0 COG0776@1|root,COG0776@2|Bacteria,2NPU6@2323|unclassified Bacteria 2|Bacteria L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hup_1 - - ko:K03530,ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding SYD1_k127_7311309_31 555088.DealDRAFT_2219 8.486e-64 231.0 COG1015@1|root,COG1015@2|Bacteria,1UJAM@1239|Firmicutes,25EZP@186801|Clostridia 186801|Clostridia C Metalloenzyme superfamily - - - - - - - - - - - - Metalloenzyme SYD1_k127_7311309_77 1507.HMPREF0262_01119 5.289e-09 66.0 COG0760@1|root,COG0760@2|Bacteria,1VE2Y@1239|Firmicutes 1239|Firmicutes M PPIC-type PPIASE domain - - - - - - - - - - - - Rotamase_3,SurA_N_3 SYD1_k127_7311309_59 665571.STHERM_c14940 6.037e-28 126.0 COG3439@1|root,COG3439@2|Bacteria 2|Bacteria D Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 SYD1_k127_7311309_25 56780.SYN_01184 3.298e-72 253.0 COG1945@1|root,COG1945@2|Bacteria,1RE9E@1224|Proteobacteria,42RQ0@68525|delta/epsilon subdivisions,2WNKW@28221|Deltaproteobacteria,2MRSR@213462|Syntrophobacterales 28221|Deltaproteobacteria S Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) - - 4.1.1.19 ko:K02626 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PvlArgDC SYD1_k127_7311309_80 671143.DAMO_1561 1.471e-06 58.0 COG4856@1|root,COG4856@2|Bacteria,2NQ44@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences dacA - - - - - - - - - - - YbbR SYD1_k127_7311309_48 478741.JAFS01000001_gene1272 2.018e-41 171.0 COG0122@1|root,COG0122@2|Bacteria,46SVK@74201|Verrucomicrobia,37GKK@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia L 8-oxoguanine DNA glycosylase, N-terminal domain alkA - 4.2.99.18 ko:K03660 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD,OGG_N SYD1_k127_7311309_54 443143.GM18_4140 2.689e-31 140.0 COG3222@1|root,COG3222@2|Bacteria,1RHCP@1224|Proteobacteria,43B9I@68525|delta/epsilon subdivisions,2X6NN@28221|Deltaproteobacteria,43SK2@69541|Desulfuromonadales 28221|Deltaproteobacteria S Guanylyl transferase CofC like - - - ko:K09931 - - - - ko00000 - - - DUF2064 SYD1_k127_7311309_83 1125863.JAFN01000001_gene1045 4.993e-06 57.0 COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria 28221|Deltaproteobacteria A Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8,zinc_ribbon_4 SYD1_k127_7311309_46 521045.Kole_0638 6.755e-43 170.0 COG1162@1|root,COG1162@2|Bacteria,2GDSA@200918|Thermotogae 200918|Thermotogae S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit - - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N SYD1_k127_7311309_32 292459.STH300 2.16e-63 245.0 COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia 186801|Clostridia G hydrolase, family 3 - - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3,Glyco_hydro_3_C SYD1_k127_7311309_65 1396418.BATQ01000106_gene5357 1.557e-23 117.0 28IVM@1|root,2Z8U0@2|Bacteria,46S57@74201|Verrucomicrobia,2IVM9@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - SYD1_k127_7311309_27 1122194.AUHU01000006_gene514 2.237e-68 248.0 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,4647N@72275|Alteromonadaceae 1236|Gammaproteobacteria M N-acetylmuramoyl-L-alanine amidase amiC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,LysM SYD1_k127_7311309_17 269799.Gmet_1014 1.248e-109 372.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Belongs to the peptidase S1C family degP-2 - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 SYD1_k127_7311309_43 865937.Gilli_2027 4.924e-51 190.0 COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1HWZZ@117743|Flavobacteriia,2P64N@244698|Gillisia 976|Bacteroidetes S Calcineurin-like phosphoesterase lpxH - 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Metallophos,Metallophos_2 SYD1_k127_7311309_60 945713.IALB_1259 8.01e-28 132.0 COG2067@1|root,COG2067@2|Bacteria 2|Bacteria I long-chain fatty acid transporting porin activity - - - - - - - - - - - - - SYD1_k127_7311309_33 459349.CLOAM0575 2.524e-62 246.0 COG4412@1|root,COG4412@2|Bacteria,2NPRE@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - ko:K09607 - - - - ko00000,ko01000,ko01002 - - - CarboxypepD_reg,FlgD_ig,Peptidase_M6 SYD1_k127_7311309_56 1379698.RBG1_1C00001G1235 4.909e-30 137.0 COG1470@1|root,COG1470@2|Bacteria 2|Bacteria S cell adhesion involved in biofilm formation - - - - - - - - - - - - CarbopepD_reg_2 SYD1_k127_7311309_39 1379698.RBG1_1C00001G1236 1.047e-55 205.0 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - ko:K06882 - - - - ko00000 - - - fn3 SYD1_k127_7311309_22 459349.CLOAM1546 5.423e-85 316.0 COG0457@1|root,COG3604@1|root,COG0457@2|Bacteria,COG3604@2|Bacteria 2|Bacteria KT transcription factor binding nifA - - ko:K02584,ko:K11914 ko02020,map02020 - - - ko00000,ko00001,ko02044,ko03000 - - - GAF,GAF_2,HTH_8,Sigma54_activat SYD1_k127_7311309_37 390989.JOEG01000003_gene4485 4.547e-58 214.0 COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4D8I2@85008|Micromonosporales 201174|Actinobacteria FP Ppx/GppA phosphatase family ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA SYD1_k127_7311309_20 671143.DAMO_2057 1.66e-88 304.0 COG0820@1|root,COG0820@2|Bacteria,2NP4V@2323|unclassified Bacteria 2|Bacteria J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Fer4_14,Radical_SAM SYD1_k127_7311309_41 889378.Spiaf_2666 9.766e-53 206.0 COG5000@1|root,COG5000@2|Bacteria,2J753@203691|Spirochaetes 203691|Spirochaetes T Histidine kinase ntrY - - - - - - - - - - - HAMP,HATPase_c,HisKA SYD1_k127_7311309_12 1123376.AUIU01000001_gene779 2.105e-127 427.0 COG2204@1|root,COG2204@2|Bacteria,3J0C2@40117|Nitrospirae 40117|Nitrospirae T Bacterial regulatory protein, Fis family - - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_7311309_63 880073.Calab_0514 8.267e-26 121.0 COG0729@1|root,COG0729@2|Bacteria 2|Bacteria M surface antigen - - - - - - - - - - - - Bac_surface_Ag,Metallophos,Peptidase_M1 SYD1_k127_7311309_85 1254432.SCE1572_02955 7.076e-05 54.0 2ANWS@1|root,31DXD@2|Bacteria,1QB7T@1224|Proteobacteria,43E5G@68525|delta/epsilon subdivisions,2X98S@28221|Deltaproteobacteria,2Z2NC@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - SYD1_k127_7311309_81 1173020.Cha6605_5674 2.817e-06 60.0 COG1664@1|root,COG1664@2|Bacteria,1G70Q@1117|Cyanobacteria 1117|Cyanobacteria M Polymer-forming cytoskeletal - - - - - - - - - - - - - SYD1_k127_7311309_51 1303518.CCALI_01897 1.832e-36 145.0 COG1595@1|root,COG1595@2|Bacteria 1303518.CCALI_01897|- K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - - SYD1_k127_7311309_6 1232410.KI421413_gene706 2.171e-181 577.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria,43S85@69541|Desulfuromonadales 28221|Deltaproteobacteria G Enolase, C-terminal TIM barrel domain eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N SYD1_k127_7311309_9 1379698.RBG1_1C00001G0607 3.215e-152 509.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria 2|Bacteria T Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase,TPR_2,TPR_8 SYD1_k127_7311309_78 1211814.CAPG01000092_gene4229 2.962e-07 58.0 29S0J@1|root,30D4W@2|Bacteria,1UAUR@1239|Firmicutes,4IM7J@91061|Bacilli,1ZJEQ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - SYD1_k127_7311309_7 234831.PSM_A0515 3.12e-171 570.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,2PZTK@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M ERAP1-like C-terminal domain - - 3.4.11.14,3.4.11.2 ko:K01256,ko:K01263 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 SYD1_k127_7311309_86 264462.Bd3721 0.0001006 55.0 29W44@1|root,30HNZ@2|Bacteria,1P948@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SYD1_k127_7311309_75 880073.Calab_3215 2.873e-11 77.0 COG0366@1|root,COG0708@1|root,COG0366@2|Bacteria,COG0708@2|Bacteria,2NREA@2323|unclassified Bacteria 2|Bacteria G Glycosyl hydrolase family 70 - - 3.1.11.2,3.2.1.1 ko:K01142,ko:K01176 ko00500,ko01100,ko03410,ko04973,map00500,map01100,map03410,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000,ko03400 - GH13 - Alpha-amylase,CBM_25,DUF1939,He_PIG SYD1_k127_7311309_45 290400.Jann_4111 5.617e-44 177.0 COG0673@1|root,COG0673@2|Bacteria,1N0VK@1224|Proteobacteria,2UEGD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA SYD1_k127_7311309_61 234267.Acid_4928 1.2e-26 116.0 29ZWG@1|root,30MXU@2|Bacteria,3Y5VK@57723|Acidobacteria 57723|Acidobacteria S DinB superfamily - - - - - - - - - - - - DinB_2 SYD1_k127_7311309_36 575540.Isop_3510 3.782e-60 218.0 COG1801@1|root,COG1801@2|Bacteria,2IYWM@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 SYD1_k127_7311309_16 215803.DB30_5098 6.556e-113 379.0 COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,42UR5@68525|delta/epsilon subdivisions,2WQET@28221|Deltaproteobacteria,2YU27@29|Myxococcales 28221|Deltaproteobacteria G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 SYD1_k127_7311309_3 1304885.AUEY01000005_gene874 1.341e-229 723.0 COG2060@1|root,COG2060@2|Bacteria,1MV1K@1224|Proteobacteria,42NCD@68525|delta/epsilon subdivisions,2WJ03@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane kdpA GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 ko:K01546 ko02020,map02020 - - - ko00000,ko00001,ko01000 3.A.3.7 - - KdpA SYD1_k127_7311309_0 1304885.AUEY01000005_gene873 9.682e-303 956.0 COG2216@1|root,COG2216@2|Bacteria,1QY0C@1224|Proteobacteria,43DGI@68525|delta/epsilon subdivisions,2X8NC@28221|Deltaproteobacteria 28221|Deltaproteobacteria P E1-E2 ATPase - - 3.6.3.12 ko:K01547 ko02020,map02020 - - - ko00000,ko00001,ko01000 3.A.3.7 - - E1-E2_ATPase,Hydrolase SYD1_k127_7311309_28 1144275.COCOR_07864 1.717e-66 231.0 COG2156@1|root,COG2156@2|Bacteria,1RABG@1224|Proteobacteria,42SC9@68525|delta/epsilon subdivisions,2WPDZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex kdpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 ko:K01548 ko02020,map02020 - - - ko00000,ko00001,ko01000 3.A.3.7 - - KdpC SYD1_k127_7311309_1 671143.DAMO_0414 8.398e-271 861.0 COG0642@1|root,COG2205@2|Bacteria,2NNNV@2323|unclassified Bacteria 2|Bacteria T Osmosensitive K+ channel His kinase sensor domain - - 2.7.13.3 ko:K07646 ko02020,map02020 M00454 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF4118,HATPase_c,HisKA,KdpD,Usp SYD1_k127_7311309_19 1254432.SCE1572_09230 1.518e-89 304.0 COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42QTM@68525|delta/epsilon subdivisions,2WN5R@28221|Deltaproteobacteria,2YXCH@29|Myxococcales 28221|Deltaproteobacteria K Transcriptional regulatory protein, C terminal kdpE - - ko:K07667 ko02020,ko02024,map02020,map02024 M00454 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C SYD1_k127_7311309_76 443143.GM18_1976 9.662e-11 70.0 COG3064@1|root,COG3064@2|Bacteria 2|Bacteria M translation initiation factor activity - - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - - SYD1_k127_7311309_30 1379698.RBG1_1C00001G0420 2.231e-64 252.0 COG0671@1|root,COG0671@2|Bacteria,2NQMG@2323|unclassified Bacteria 2|Bacteria I Phosphoesterase, PA-phosphatase related protein - - - - - - - - - - - - PAP2,PAP2_3 SYD1_k127_7311309_4 644966.Tmar_0901 8.467e-218 696.0 COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3WD0A@538999|Clostridiales incertae sedis 186801|Clostridia C TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - 6.2.1.13 ko:K01905,ko:K22224 ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120 - R00229,R00920 RC00004,RC00012,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig SYD1_k127_7311309_62 357808.RoseRS_0192 2.977e-26 110.0 COG2154@1|root,COG2154@2|Bacteria,2G7GN@200795|Chloroflexi,375ZK@32061|Chloroflexia 32061|Chloroflexia H PFAM transcriptional coactivator pterin dehydratase - - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a SYD1_k127_7311309_72 1449063.JMLS01000012_gene5442 9.551e-13 72.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,26Z9P@186822|Paenibacillaceae 91061|Bacilli S Iron-sulfur cluster assembly protein - - - - - - - - - - - - FeS_assembly_P SYD1_k127_7311309_58 926550.CLDAP_20390 3.172e-29 130.0 COG2146@1|root,COG2146@2|Bacteria,2G7AG@200795|Chloroflexi 200795|Chloroflexi P PFAM Rieske 2Fe-2S domain protein - - 1.7.1.15 ko:K00363,ko:K05710 ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220 M00530,M00545 R00787,R06782,R06783 RC00098,RC00176 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske SYD1_k127_7311309_47 525904.Tter_1695 1.486e-42 175.0 COG0822@1|root,COG0822@2|Bacteria,2NPXN@2323|unclassified Bacteria 2|Bacteria C NifU-like N terminal domain nifU - - ko:K04488 - - - - ko00000 - - - NifU_N SYD1_k127_7311309_8 1128421.JAGA01000002_gene1806 8.844e-157 505.0 COG0520@1|root,COG0520@2|Bacteria,2NNS0@2323|unclassified Bacteria 2|Bacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 SYD1_k127_7311309_18 309801.trd_0379 6.023e-98 337.0 COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi,27Y27@189775|Thermomicrobia 189775|Thermomicrobia O Uncharacterized protein family (UPF0051) - - - ko:K09015 - - - - ko00000 - - - UPF0051 SYD1_k127_7311309_2 479434.Sthe_1523 2.011e-235 741.0 COG0719@1|root,COG0719@2|Bacteria,2G5TI@200795|Chloroflexi,27XVW@189775|Thermomicrobia 189775|Thermomicrobia O Uncharacterized protein family (UPF0051) - - - ko:K09014 - - - - ko00000 - - - UPF0051 SYD1_k127_7311309_15 479434.Sthe_1522 4.957e-113 371.0 COG0396@1|root,COG0396@2|Bacteria,2G5S6@200795|Chloroflexi,27XVN@189775|Thermomicrobia 189775|Thermomicrobia O ATPases associated with a variety of cellular activities - - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran SYD1_k127_7311309_64 1267535.KB906767_gene197 3.372e-24 108.0 COG0316@1|root,COG0316@2|Bacteria,3Y518@57723|Acidobacteria,2JJGN@204432|Acidobacteriia 204432|Acidobacteriia S Belongs to the HesB IscA family - - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn SYD1_k127_7311309_50 1192034.CAP_5767 2.029e-37 147.0 COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,42VYV@68525|delta/epsilon subdivisions,2WRGQ@28221|Deltaproteobacteria,2Z0X7@29|Myxococcales 28221|Deltaproteobacteria K MerR, DNA binding - - - ko:K19591 - M00769 - - ko00000,ko00002,ko01504,ko03000 - - - MerR,MerR-DNA-bind,MerR_1 SYD1_k127_7311309_84 1457250.BBMO01000001_gene1538 5.363e-05 51.0 COG3794@1|root,arCOG02926@2157|Archaea 2157|Archaea C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - Copper-bind,Cupredoxin_1 SYD1_k127_7311309_88 717605.Theco_0795 0.0002283 53.0 COG5528@1|root,COG5528@2|Bacteria,1VW9Q@1239|Firmicutes,4HWSC@91061|Bacilli,26YQB@186822|Paenibacillaceae 91061|Bacilli S Predicted integral membrane protein (DUF2269) - - - - - - - - - - - - DUF2269 SYD1_k127_7311309_42 1156919.QWC_26308 3.575e-51 207.0 COG1012@1|root,COG1012@2|Bacteria,1R656@1224|Proteobacteria,2VPB8@28216|Betaproteobacteria,3T6PT@506|Alcaligenaceae 28216|Betaproteobacteria C Acyl-CoA reductase (LuxC) - - - - - - - - - - - - LuxC SYD1_k127_7311309_40 1160707.AJIK01000024_gene1728 3.109e-55 208.0 COG0318@1|root,COG0318@2|Bacteria,1UKBR@1239|Firmicutes,4ITH5@91061|Bacilli,26GS4@186818|Planococcaceae 91061|Bacilli IQ Acyl-protein synthetase, LuxE - - - - - - - - - - - - LuxE SYD1_k127_7311309_68 598659.NAMH_0925 1.805e-15 91.0 COG1611@1|root,COG1611@2|Bacteria,1NNFY@1224|Proteobacteria 1224|Proteobacteria S Possible lysine decarboxylase - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox SYD1_k127_7311309_5 123214.PERMA_0609 2.459e-188 605.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G425@200783|Aquificae 200783|Aquificae H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase SYD1_k127_7311309_34 251229.Chro_1450 1.579e-61 220.0 COG0346@1|root,COG0400@1|root,COG0346@2|Bacteria,COG0400@2|Bacteria 2|Bacteria S palmitoyl-(protein) hydrolase activity - - - ko:K06999,ko:K15975 - - - - ko00000 - - - Abhydrolase_2,Glyoxalase SYD1_k127_7311309_73 880073.Calab_0921 8.64e-12 79.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - DUF4157,FctA,Peptidase_M43 SYD1_k127_7311309_89 324602.Caur_3270 0.0003069 54.0 COG0739@1|root,COG1572@1|root,COG3227@1|root,COG5640@1|root,COG0739@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria,COG5640@2|Bacteria,2G8C6@200795|Chloroflexi,377AX@32061|Chloroflexia 32061|Chloroflexia E PFAM peptidase M4 thermolysin - - - - - - - - - - - - FTP,Peptidase_M4,Peptidase_M4_C SYD1_k127_7311309_69 377629.TERTU_0017 1.504e-14 88.0 COG2304@1|root,COG2304@2|Bacteria,1R7H7@1224|Proteobacteria,1SEG0@1236|Gammaproteobacteria,2PQ3H@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Zinc-dependent metalloprotease - - - - - - - - - - - - VWA,VWA_2 SYD1_k127_7311309_13 1500890.JQNL01000001_gene3697 1.368e-117 394.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,1X4PF@135614|Xanthomonadales 135614|Xanthomonadales I fatty acid desaturase desC - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase SYD1_k127_7311309_66 378806.STAUR_1528 2.806e-22 112.0 COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales 28221|Deltaproteobacteria E Glycine cleavage T-protein C-terminal barrel domain - - 2.1.2.10 ko:K00605,ko:K06980 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000,ko03016 - - - GCV_T,GCV_T_C SYD1_k127_7311309_52 290397.Adeh_1024 1.359e-31 127.0 COG0640@1|root,COG0640@2|Bacteria,1N7I7@1224|Proteobacteria,42VTU@68525|delta/epsilon subdivisions,2WRGJ@28221|Deltaproteobacteria,2YVHK@29|Myxococcales 28221|Deltaproteobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 SYD1_k127_7311309_24 552811.Dehly_1422 1.548e-80 282.0 COG0500@1|root,COG2226@2|Bacteria,2G6GD@200795|Chloroflexi,34CS0@301297|Dehalococcoidia 301297|Dehalococcoidia Q Ribosomal protein L11 methyltransferase (PrmA) - - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_31 SYD1_k127_7311309_49 867903.ThesuDRAFT_00058 3.508e-41 164.0 COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia,3WDFB@538999|Clostridiales incertae sedis 186801|Clostridia F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran SYD1_k127_7311309_23 58123.JOFJ01000001_gene3202 6.35e-81 287.0 COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4EFV0@85012|Streptosporangiales 201174|Actinobacteria S Domain of unknown function (DUF1731) - - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase SYD1_k127_7311309_35 398767.Glov_1033 1.638e-60 238.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,43TYK@69541|Desulfuromonadales 28221|Deltaproteobacteria C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase ndh2 - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 SYD1_k127_7311309_70 616991.JPOO01000003_gene109 2.895e-14 78.0 2CK2Q@1|root,303GN@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_7311309_82 478741.JAFS01000002_gene410 3.397e-06 56.0 2CK2Q@1|root,329IJ@2|Bacteria,46ZCM@74201|Verrucomicrobia,37GU0@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia - - - - - - - - - - - - - - - SYD1_k127_7311309_38 1382304.JNIL01000001_gene468 1.391e-57 218.0 COG0500@1|root,COG2226@2|Bacteria,1UZN6@1239|Firmicutes,4HD89@91061|Bacilli 91061|Bacilli Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 SYD1_k127_7311309_71 543728.Vapar_3229 1.323e-13 81.0 COG2944@1|root,COG2944@2|Bacteria,1N21E@1224|Proteobacteria,2VUAS@28216|Betaproteobacteria,4AF56@80864|Comamonadaceae 28216|Betaproteobacteria K Helix-turn-helix domain protein - - - - - - - - - - - - HTH_3,HTH_31 SYD1_k127_7311309_11 1232410.KI421415_gene3026 4.5e-143 496.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2X28Y@28221|Deltaproteobacteria,43U5A@69541|Desulfuromonadales 28221|Deltaproteobacteria I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - 3HCDH,3HCDH_N,ECH_1 SYD1_k127_7311309_10 765869.BDW_06795 8.131e-144 469.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2MSMB@213481|Bdellovibrionales,2WM0B@28221|Deltaproteobacteria 213481|Bdellovibrionales I Belongs to the thiolase family - - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N SYD1_k127_7311309_14 861299.J421_2707 9.34e-117 413.0 COG1022@1|root,COG1022@2|Bacteria,1ZT60@142182|Gemmatimonadetes 142182|Gemmatimonadetes I AMP-binding enzyme - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding SYD1_k127_7311309_87 1499689.CCNN01000007_gene849 0.000224 53.0 2EAZQ@1|root,3350J@2|Bacteria,1VHQ8@1239|Firmicutes,24RFD@186801|Clostridia,36NC5@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - SYD1_k127_7311309_53 570268.ANBB01000002_gene307 1.646e-31 145.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4EGFA@85012|Streptosporangiales 201174|Actinobacteria KLT PASTA pknL GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase SYD1_k127_7311309_79 864702.OsccyDRAFT_0035 1.401e-06 59.0 COG0457@1|root,COG0457@2|Bacteria,1GD8A@1117|Cyanobacteria,1HF6N@1150|Oscillatoriales 1117|Cyanobacteria S Soluble NSF attachment protein, SNAP - - - - - - - - - - - - TPR_12 SYD1_k127_7318010_0 1116472.MGMO_98c00170 2.407e-52 194.0 2C2I0@1|root,31SYT@2|Bacteria,1RM4F@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SYD1_k127_7318010_1 1120949.KB903304_gene6906 1.228e-22 104.0 COG4430@1|root,COG4430@2|Bacteria,2IN25@201174|Actinobacteria,4DCTP@85008|Micromonosporales 201174|Actinobacteria S Domain of unknown function (DUF1905) - - - - - - - - - - - - DUF1905,OmdA SYD1_k127_7484611_30 379066.GAU_3478 2.623e-66 232.0 COG0793@1|root,COG0793@2|Bacteria 2|Bacteria M Belongs to the peptidase S41A family - - - - - - - - - - - - Peptidase_S41 SYD1_k127_7484611_21 1944.JOAZ01000001_gene4132 6.564e-90 314.0 COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,41956@629295|Streptomyces griseus group 201174|Actinobacteria E DegT/DnrJ/EryC1/StrS aminotransferase family aspC - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 SYD1_k127_7484611_27 1379698.RBG1_1C00001G0818 5.819e-68 237.0 COG0605@1|root,COG0605@2|Bacteria,2NP62@2323|unclassified Bacteria 2|Bacteria P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodA GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010269,GO:0010447,GO:0016020,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0020012,GO:0030145,GO:0030682,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052059,GO:0052173,GO:0052200,GO:0052385,GO:0052550,GO:0052564,GO:0052567,GO:0052572,GO:0055114,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071291,GO:0071450,GO:0071451,GO:0071944,GO:0072593,GO:0075136,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 ko:K03601,ko:K04564 ko03430,ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map03430,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000,ko03400 - - iAF1260.b1656,iAPECO1_1312.APECO1_736,iB21_1397.B21_01616,iBWG_1329.BWG_1471,iE2348C_1286.E2348C_1742,iE2348C_1286.E2348C_4213,iEC042_1314.EC042_1825,iEC55989_1330.EC55989_1824,iECABU_c1320.ECABU_c19090,iECBD_1354.ECBD_1987,iECB_1328.ECB_01626,iECDH10B_1368.ECDH10B_1790,iECDH1ME8569_1439.ECDH1ME8569_1601,iECD_1391.ECD_01626,iECED1_1282.ECED1_1855,iECH74115_1262.ECH74115_2368,iECIAI1_1343.ECIAI1_1708,iECO103_1326.ECO103_1797,iECO111_1330.ECO111_2126,iECO26_1355.ECO26_2385,iECOK1_1307.ECOK1_1775,iECP_1309.ECP_1601,iECS88_1305.ECS88_1705,iECSE_1348.ECSE_1780,iECSF_1327.ECSF_3769,iECSP_1301.ECSP_2222,iECUMN_1333.ECUMN_1946,iECW_1372.ECW_m1823,iECs_1301.ECs2365,iEKO11_1354.EKO11_2118,iETEC_1333.ETEC_1691,iEcDH1_1363.EcDH1_1984,iEcE24377_1341.EcE24377A_1869,iEcHS_1320.EcHS_A1735,iEcSMS35_1347.EcSMS35_1542,iEcolC_1368.EcolC_1973,iG2583_1286.G2583_2051,iJO1366.b1656,iJR904.b1656,iLF82_1304.LF82_2148,iNJ661.Rv3846,iNRG857_1313.NRG857_08300,iSBO_1134.SBO_1475,iSDY_1059.SDY_1882,iSFV_1184.SFV_1678,iSF_1195.SF1684,iSFxv_1172.SFxv_1892,iSSON_1240.SSON_1500,iS_1188.S1816,iSbBS512_1146.SbBS512_E1853,iUMN146_1321.UM146_08870,iUMNK88_1353.UMNK88_2117,iUTI89_1310.UTI89_C1847,iWFL_1372.ECW_m1823,iY75_1357.Y75_RS08680,iZ_1308.Z2678,ic_1306.c2050 Sod_Fe_C,Sod_Fe_N SYD1_k127_7484611_52 497964.CfE428DRAFT_3635 4.476e-18 100.0 COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,46S7F@74201|Verrucomicrobia 74201|Verrucomicrobia K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - - - - - - - - - - GreA_GreB,GreA_GreB_N SYD1_k127_7484611_37 290397.Adeh_2849 7.391e-53 200.0 COG0697@1|root,COG0697@2|Bacteria,1PX5W@1224|Proteobacteria,42MGR@68525|delta/epsilon subdivisions,2X5KV@28221|Deltaproteobacteria,2YY40@29|Myxococcales 28221|Deltaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA SYD1_k127_7484611_31 502025.Hoch_0564 7.349e-63 243.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2YWB2@29|Myxococcales 28221|Deltaproteobacteria H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.19,2.6.1.22 ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 SYD1_k127_7484611_18 502025.Hoch_3436 1.105e-106 367.0 COG1196@1|root,COG1196@2|Bacteria,1R3XQ@1224|Proteobacteria,42YF5@68525|delta/epsilon subdivisions,2WUDV@28221|Deltaproteobacteria,2YUE5@29|Myxococcales 28221|Deltaproteobacteria D HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase - - - - - - - - - - - - 5_nucleotid SYD1_k127_7484611_29 459349.CLOAM1240 9.528e-67 248.0 COG1207@1|root,COG1207@2|Bacteria,2NQ8F@2323|unclassified Bacteria 2|Bacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_4 SYD1_k127_7484611_36 1379698.RBG1_1C00001G1850 2.152e-53 211.0 COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria 2|Bacteria S Rhomboid family - - - - - - - - - - - - Rhomboid SYD1_k127_7484611_12 404589.Anae109_2993 4.963e-131 455.0 COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42P3Y@68525|delta/epsilon subdivisions,2WJG5@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C SYD1_k127_7484611_2 240015.ACP_0328 1.121e-228 724.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,3Y3NX@57723|Acidobacteria,2JKIA@204432|Acidobacteriia 204432|Acidobacteriia C Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg - - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - POR,POR_N SYD1_k127_7484611_13 1198114.AciX9_0825 3.037e-130 428.0 COG0379@1|root,COG0379@2|Bacteria,3Y328@57723|Acidobacteria,2JHY8@204432|Acidobacteriia 204432|Acidobacteriia H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA SYD1_k127_7484611_50 1183438.GKIL_0334 1.275e-20 92.0 COG1146@1|root,COG1146@2|Bacteria,1G7Q8@1117|Cyanobacteria 1117|Cyanobacteria C 4Fe-4S ferredoxin, iron-sulfur binding - - - - - - - - - - - - Fer4,Fer4_2,Fer4_7 SYD1_k127_7484611_6 335543.Sfum_0290 4.808e-145 489.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,42Q00@68525|delta/epsilon subdivisions,2WJEM@28221|Deltaproteobacteria,2MSIQ@213462|Syntrophobacterales 28221|Deltaproteobacteria M Transglycosylase mrcB - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H SYD1_k127_7484611_40 1123242.JH636434_gene3237 2.27e-41 178.0 COG0461@1|root,COG0461@2|Bacteria,2IZA7@203682|Planctomycetes 203682|Planctomycetes F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran SYD1_k127_7484611_0 1379698.RBG1_1C00001G0460 0.0 1094.0 COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria 2|Bacteria L DNA polymerase dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon SYD1_k127_7484611_14 880073.Calab_1391 6.43e-127 413.0 COG0825@1|root,COG0825@2|Bacteria,2NNVQ@2323|unclassified Bacteria 2|Bacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA,Carboxyl_trans SYD1_k127_7484611_54 316067.Geob_2107 2.083e-15 79.0 COG2835@1|root,COG2835@2|Bacteria,1Q1BG@1224|Proteobacteria,42WTN@68525|delta/epsilon subdivisions,2WSI9@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Belongs to the UPF0434 family - - - ko:K09791 - - - - ko00000 - - - Trm112p SYD1_k127_7484611_35 1353276.JADR01000010_gene1608 1.648e-53 218.0 COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1HYJD@117743|Flavobacteriia 976|Bacteroidetes S Peptidase family C25 porU - - - - - - - - - - - Peptidase_C25 SYD1_k127_7484611_38 880073.Calab_1394 3.632e-50 190.0 COG2067@1|root,COG2067@2|Bacteria,2NPQZ@2323|unclassified Bacteria 2|Bacteria I Two component regulator propeller porV - - - - - - - - - - - - SYD1_k127_7484611_20 1379698.RBG1_1C00001G1787 3.351e-94 347.0 COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria,2NPRE@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - DUF1863,PQQ_2 SYD1_k127_7484611_59 1379698.RBG1_1C00001G1786 1.492e-11 74.0 2CUTJ@1|root,32SW3@2|Bacteria,2NRD1@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_7484611_63 1379698.RBG1_1C00001G1785 1.038e-09 70.0 2EAWV@1|root,334Y2@2|Bacteria,2NRSF@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_7484611_64 1463841.JOIR01000047_gene2842 6.012e-09 67.0 COG3391@1|root,COG3391@2|Bacteria,2I3DQ@201174|Actinobacteria 201174|Actinobacteria S NHL repeat - - - - - - - - - - - - NHL SYD1_k127_7484611_33 1379698.RBG1_1C00001G1783 2.075e-59 237.0 COG5448@1|root,COG5448@2|Bacteria,2NPPC@2323|unclassified Bacteria 2|Bacteria S Glycoside hydrolase family 24 - - - - - - - - - - - - DUF2460 SYD1_k127_7484611_67 1191523.MROS_0530 1.368e-07 66.0 COG4775@1|root,COG4775@2|Bacteria 2|Bacteria M membrane organization - - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA SYD1_k127_7484611_4 1125863.JAFN01000001_gene929 7.514e-189 613.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria 28221|Deltaproteobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 SYD1_k127_7484611_22 717605.Theco_1813 1.659e-84 306.0 COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,26T6Z@186822|Paenibacillaceae 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII SYD1_k127_7484611_9 1122137.AQXF01000005_gene1288 7.781e-136 461.0 COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,2TSPJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Histidine ammonia-lyase hutH - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic SYD1_k127_7484611_1 316274.Haur_0629 4.592e-257 807.0 COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi,376GE@32061|Chloroflexia 32061|Chloroflexia E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N SYD1_k127_7484611_15 562970.Btus_0929 6.088e-118 394.0 COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,4HAVY@91061|Bacilli,27837@186823|Alicyclobacillaceae 91061|Bacilli Q Amidohydrolase family hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU39370 Amidohydro_1,Amidohydro_3 SYD1_k127_7484611_5 1379698.RBG1_1C00001G1247 2.999e-155 506.0 COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria 2|Bacteria E Formiminotransferase-cyclodeaminase ftcD - 2.1.2.5,4.3.1.4 ko:K00603,ko:K01746,ko:K13990 ko00340,ko00670,ko01100,map00340,map00670,map01100 - R02287,R02302,R03189 RC00165,RC00221,RC00223,RC00688,RC00870 ko00000,ko00001,ko01000,ko03036,ko04147 - - - FTCD,FTCD_C,FTCD_N SYD1_k127_7484611_57 502025.Hoch_0258 1.645e-12 81.0 COG0457@1|root,COG3170@1|root,COG0457@2|Bacteria,COG3170@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales 28221|Deltaproteobacteria NU Tetratricopeptide repeats - - - - - - - - - - - - TPR_11,TPR_16,TPR_19 SYD1_k127_7484611_48 1379270.AUXF01000006_gene26 2.775e-24 119.0 COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_8 SYD1_k127_7484611_32 768710.DesyoDRAFT_3258 7.753e-61 238.0 COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,26144@186807|Peptococcaceae 186801|Clostridia S PFAM PHP domain - - 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - PHP SYD1_k127_7484611_58 867903.ThesuDRAFT_00669 2.109e-12 74.0 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,3WDDX@538999|Clostridiales incertae sedis 186801|Clostridia L Helix-hairpin-helix motif comEA - - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB SYD1_k127_7484611_3 639282.DEFDS_1109 6.279e-196 628.0 COG2804@1|root,COG2804@2|Bacteria,2GEP7@200930|Deferribacteres 200930|Deferribacteres NU General secretory system II protein E domain protein - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N SYD1_k127_7484611_8 404589.Anae109_0668 1.484e-137 446.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2YWXD@29|Myxococcales 28221|Deltaproteobacteria NU twitching motility protein pilT-4 - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE SYD1_k127_7484611_7 379066.GAU_2568 1.159e-139 455.0 COG1459@1|root,COG1459@2|Bacteria,1ZT63@142182|Gemmatimonadetes 142182|Gemmatimonadetes U Type II secretion system (T2SS), protein F - - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF SYD1_k127_7484611_24 1379698.RBG1_1C00001G1740 1.306e-74 273.0 COG3852@1|root,COG3852@2|Bacteria 2|Bacteria T phosphorelay sensor kinase activity - - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HAMP,HATPase_c,HisKA,PAS,PAS_8,PAS_9 SYD1_k127_7484611_10 1379698.RBG1_1C00001G1210 1.438e-134 443.0 COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria 2|Bacteria T Two component, sigma54 specific, transcriptional regulator, Fis family nla19 - - ko:K02667,ko:K07713,ko:K07714,ko:K19641 ko02020,map02020 M00499,M00500,M00501,M00772 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_7484611_61 1242864.D187_006601 5.342e-11 68.0 COG4968@1|root,COG4968@2|Bacteria,1QXNR@1224|Proteobacteria,43C4N@68525|delta/epsilon subdivisions,2WRDZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria NU Pfam:N_methyl_2 pilA-N - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin_PilA SYD1_k127_7484611_60 243231.GSU1776 1.988e-11 70.0 COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,42ZXF@68525|delta/epsilon subdivisions,2WV6V@28221|Deltaproteobacteria,43UYQ@69541|Desulfuromonadales 28221|Deltaproteobacteria U Pfam:N_methyl_2 oxpG - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl SYD1_k127_7484611_25 391625.PPSIR1_04123 4.454e-73 260.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NSM@68525|delta/epsilon subdivisions,2WJXQ@28221|Deltaproteobacteria,2YXY8@29|Myxococcales 28221|Deltaproteobacteria V AAA domain, putative AbiEii toxin, Type IV TA system pilH - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SYD1_k127_7484611_45 1173020.Cha6605_4838 1.215e-29 137.0 COG1277@1|root,COG1277@2|Bacteria,1G09F@1117|Cyanobacteria 1117|Cyanobacteria S ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - - - - - - - - - - ABC2_membrane_2 SYD1_k127_7484611_53 330214.NIDE3436 1.747e-16 93.0 COG0457@1|root,COG0457@2|Bacteria 330214.NIDE3436|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - SYD1_k127_7484611_34 243231.GSU2043 5.663e-55 213.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales 28221|Deltaproteobacteria M Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 SYD1_k127_7484611_69 477974.Daud_0971 3.031e-06 58.0 COG4970@1|root,COG4970@2|Bacteria,1U4QW@1239|Firmicutes,25IDV@186801|Clostridia,266MB@186807|Peptococcaceae 186801|Clostridia U TIGRFAM general secretion pathway protein H - - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - N_methyl SYD1_k127_7484611_71 177437.HRM2_27670 6.316e-05 54.0 COG4967@1|root,COG4967@2|Bacteria,1NI49@1224|Proteobacteria,42X6W@68525|delta/epsilon subdivisions,2WSY4@28221|Deltaproteobacteria,2MMCT@213118|Desulfobacterales 28221|Deltaproteobacteria NU Prokaryotic N-terminal methylation motif - - - ko:K02458,ko:K02671 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15 - - N_methyl SYD1_k127_7484611_62 1122605.KB893626_gene2400 2.397e-10 74.0 COG2706@1|root,COG5492@1|root,COG2706@2|Bacteria,COG5492@2|Bacteria,4PMF3@976|Bacteroidetes,1IT6W@117747|Sphingobacteriia 976|Bacteroidetes N PFAM Bacterial Ig-like domain (group 2) - - - - - - - - - - - - CHU_C,VCBS SYD1_k127_7484611_70 187272.Mlg_0860 2.185e-05 57.0 COG4726@1|root,COG4726@2|Bacteria,1NQF4@1224|Proteobacteria 1224|Proteobacteria NU Pilus assembly protein PilX - - - - - - - - - - - - - SYD1_k127_7484611_73 187272.Mlg_0860 7.643e-05 56.0 COG4726@1|root,COG4726@2|Bacteria,1NQF4@1224|Proteobacteria 1224|Proteobacteria NU Pilus assembly protein PilX - - - - - - - - - - - - - SYD1_k127_7484611_28 882082.SaccyDRAFT_0176 1.046e-67 258.0 COG1287@1|root,COG1287@2|Bacteria,2GMZM@201174|Actinobacteria,4E0ZH@85010|Pseudonocardiales 201174|Actinobacteria S oligosaccharyl transferase activity - - - - - - - - - - - - - SYD1_k127_7484611_44 266117.Rxyl_0932 3e-31 141.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity MA20_42315 - - - - - - - - - - - PMT_2 SYD1_k127_7484611_23 290397.Adeh_0641 1.06e-81 285.0 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales 28221|Deltaproteobacteria NU pilus assembly protein pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 SYD1_k127_7484611_55 338966.Ppro_0993 3.467e-15 85.0 COG3166@1|root,COG3166@2|Bacteria,1Q1I0@1224|Proteobacteria,42W65@68525|delta/epsilon subdivisions,2WS79@28221|Deltaproteobacteria,43UXE@69541|Desulfuromonadales 28221|Deltaproteobacteria NU Fimbrial assembly protein (PilN) pilN - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN SYD1_k127_7484611_56 1095769.CAHF01000003_gene1043 3.497e-14 80.0 COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,2VH68@28216|Betaproteobacteria,473PW@75682|Oxalobacteraceae 28216|Betaproteobacteria NU Pilus assembly protein, PilO pilO - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - PilO SYD1_k127_7484611_26 1125863.JAFN01000001_gene2283 1.322e-72 267.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria 28221|Deltaproteobacteria U Type II and III secretion system protein pilQ - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N SYD1_k127_7484611_49 1128421.JAGA01000003_gene2989 1.356e-23 117.0 COG0337@1|root,COG0337@2|Bacteria,2NP5Z@2323|unclassified Bacteria 2|Bacteria E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase,SKI SYD1_k127_7484611_43 252305.OB2597_10766 1.035e-32 137.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2U70Y@28211|Alphaproteobacteria,2PE76@252301|Oceanicola 28211|Alphaproteobacteria L Conserved hypothetical protein 95 rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 SYD1_k127_7484611_39 1131269.AQVV01000022_gene2242 1.02e-45 173.0 COG0669@1|root,COG0669@2|Bacteria 2|Bacteria H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like SYD1_k127_7484611_17 644966.Tmar_0353 5.915e-110 381.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WCM1@538999|Clostridiales incertae sedis 186801|Clostridia E Aminotransferase class I and II aspB - 2.6.1.1 ko:K00812,ko:K10907 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - iHN637.CLJU_RS06550 Aminotran_1_2 SYD1_k127_7484611_51 1396141.BATP01000007_gene5670 2.621e-20 105.0 COG2331@1|root,COG2331@2|Bacteria,46T2S@74201|Verrucomicrobia,2IW1E@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 SYD1_k127_7484611_19 1121430.JMLG01000002_gene982 1.01e-105 353.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,25ZZB@186807|Peptococcaceae 186801|Clostridia S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 SYD1_k127_7484611_74 330214.NIDE4149 0.0008194 49.0 COG1413@1|root,COG1413@2|Bacteria,3J1E2@40117|Nitrospirae 40117|Nitrospirae C Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - HEAT_2,HEAT_PBS SYD1_k127_7484611_42 977880.RALTA_A3157 1.128e-35 152.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,1K1PV@119060|Burkholderiaceae 28216|Betaproteobacteria LU DNA protecting protein DprA smf - - ko:K04096 - - - - ko00000 - - - DNA_processg_A SYD1_k127_7484611_41 1123288.SOV_3c03780 1.578e-39 159.0 COG1560@1|root,COG1560@2|Bacteria,1U76T@1239|Firmicutes,4H2PH@909932|Negativicutes 909932|Negativicutes M Lipid A biosynthesis - - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans SYD1_k127_7484611_47 880073.Calab_2775 1.58e-27 114.0 COG4191@1|root,COG4191@2|Bacteria 2|Bacteria T Histidine kinase - - 2.7.11.1,4.6.1.1 ko:K01768,ko:K12132 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko01001 - - - DUF3467 SYD1_k127_7484611_46 880072.Desac_0283 9.023e-29 134.0 COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M6C@68525|delta/epsilon subdivisions,2WM3G@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,Response_reg SYD1_k127_7484611_72 398512.JQKC01000002_gene1942 7.002e-05 48.0 2DPV4@1|root,333HA@2|Bacteria,1VH7Z@1239|Firmicutes,24SC2@186801|Clostridia,3WQ8C@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - SYD1_k127_7484611_16 861299.J421_3894 1.003e-114 387.0 COG1109@1|root,COG1109@2|Bacteria,1ZSNW@142182|Gemmatimonadetes 142182|Gemmatimonadetes G Phosphoglucomutase/phosphomannomutase, C-terminal domain - - 5.4.2.8 ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV SYD1_k127_7484611_11 1379698.RBG1_1C00001G0688 3.129e-133 456.0 COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria 2|Bacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iAF987.Gmet_1487 GATase_6,SIS SYD1_k127_7784632_20 945713.IALB_2816 8.774e-59 218.0 COG3203@1|root,COG3203@2|Bacteria 2|Bacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Alginate_exp,OprD,Porin_4 SYD1_k127_7784632_8 867903.ThesuDRAFT_01219 4.812e-114 378.0 COG0226@1|root,COG0226@2|Bacteria,1UFGH@1239|Firmicutes,24D85@186801|Clostridia,3WDS1@538999|Clostridiales incertae sedis 186801|Clostridia P TIGRFAM phosphate ABC transporter, phosphate-binding protein - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 SYD1_k127_7784632_12 204669.Acid345_2974 9.476e-86 295.0 COG0573@1|root,COG0573@2|Bacteria,3Y42Y@57723|Acidobacteria,2JIJN@204432|Acidobacteriia 204432|Acidobacteriia P probably responsible for the translocation of the substrate across the membrane - - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 SYD1_k127_7784632_13 1191523.MROS_2638 2.642e-85 306.0 COG0581@1|root,COG0581@2|Bacteria 2|Bacteria P inorganic phosphate transmembrane transporter activity pstA GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - ko:K02037,ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 SYD1_k127_7784632_21 379066.GAU_2370 1.81e-54 201.0 COG0704@1|root,COG0704@2|Bacteria 2|Bacteria P negative regulation of phosphate transmembrane transport phoU GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - ko:K02039 - - - - ko00000 - - - PhoU SYD1_k127_7784632_11 292459.STH746 1.237e-99 333.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia 186801|Clostridia P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran SYD1_k127_7784632_17 316067.Geob_3554 2.328e-65 241.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,43TY2@69541|Desulfuromonadales 28221|Deltaproteobacteria T Phosphate sensor histidine kinase, HAMP and PAS domain-containing phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like SYD1_k127_7784632_18 570967.JMLV01000002_gene1873 5.094e-64 232.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,2JPZV@204441|Rhodospirillales 204441|Rhodospirillales T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain phoB - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C SYD1_k127_7784632_9 56780.SYN_01524 2.42e-113 385.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2MR54@213462|Syntrophobacterales 28221|Deltaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG SYD1_k127_7784632_15 1125863.JAFN01000001_gene1341 5.376e-70 247.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria 28221|Deltaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG SYD1_k127_7784632_22 357808.RoseRS_0537 3.962e-48 186.0 COG2129@1|root,COG2129@2|Bacteria 2|Bacteria L metallophosphoesterase - - - ko:K07096 - - - - ko00000 - - - Metallophos,Metallophos_2,Metallophos_3 SYD1_k127_7784632_23 398579.Spea_0138 2.297e-20 100.0 COG1476@1|root,COG1476@2|Bacteria,1N6SS@1224|Proteobacteria,1SCB0@1236|Gammaproteobacteria,2QCSC@267890|Shewanellaceae 1236|Gammaproteobacteria K PFAM helix-turn-helix domain protein - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 SYD1_k127_7784632_26 1247726.MIM_c24760 5.366e-06 59.0 2E3S2@1|root,32YPN@2|Bacteria,1NDK1@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SYD1_k127_7784632_19 861299.J421_2976 1.757e-60 218.0 COG1657@1|root,COG1657@2|Bacteria,1ZSPV@142182|Gemmatimonadetes 142182|Gemmatimonadetes I Domain of unknown function (DUF4159) - - - - - - - - - - - - DUF4159 SYD1_k127_7784632_14 880073.Calab_0677 8.714e-80 301.0 COG1196@1|root,COG1196@2|Bacteria,2NNSS@2323|unclassified Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - - SYD1_k127_7784632_3 945713.IALB_0313 2.196e-160 529.0 2CD20@1|root,2Z7SQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_7784632_25 251229.Chro_5346 3.517e-11 74.0 COG0451@1|root,COG0451@2|Bacteria,1G2DP@1117|Cyanobacteria,3VIUA@52604|Pleurocapsales 1117|Cyanobacteria GM PFAM NAD dependent epimerase dehydratase family - - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase SYD1_k127_7784632_5 886293.Sinac_3963 1.492e-149 493.0 COG2234@1|root,COG2234@2|Bacteria,2IWTP@203682|Planctomycetes 2|Bacteria S Peptidase family M28 - - - - - - - - - - - - PA,Peptidase_M28 SYD1_k127_7784632_7 880073.Calab_1134 2.893e-128 444.0 COG2091@1|root,COG2091@2|Bacteria,2NQGR@2323|unclassified Bacteria 2|Bacteria H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 SYD1_k127_7784632_4 526227.Mesil_2803 1.947e-156 501.0 COG4638@1|root,COG4638@2|Bacteria 2|Bacteria P Rieske (2fe-2S) - - 1.14.15.7 ko:K00499 ko00260,map00260 - R07409 RC00087 ko00000,ko00001,ko01000 - - - Rieske,Ring_hydroxyl_A SYD1_k127_7784632_1 1123073.KB899241_gene2226 3.96e-291 911.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,1X333@135614|Xanthomonadales 135614|Xanthomonadales I converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 SYD1_k127_7784632_10 1278073.MYSTI_05613 9.431e-100 357.0 COG0421@1|root,COG0421@2|Bacteria,1QX98@1224|Proteobacteria,43C2D@68525|delta/epsilon subdivisions,2X7CZ@28221|Deltaproteobacteria,2Z3FM@29|Myxococcales 28221|Deltaproteobacteria E Spermine/spermidine synthase domain speE - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synth SYD1_k127_7784632_24 459349.CLOAM0984 2.72e-16 94.0 COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria 2|Bacteria M Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25 SYD1_k127_7784632_2 649638.Trad_0899 1.498e-199 631.0 COG1249@1|root,COG1249@2|Bacteria,1WI3A@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim SYD1_k127_7784632_6 498848.TaqDRAFT_4741 6.229e-137 450.0 COG0508@1|root,COG0508@2|Bacteria,1WIIU@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding SYD1_k127_7784632_0 649638.Trad_0897 0.0 1127.0 COG0567@1|root,COG0567@2|Bacteria,1WIKA@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C dehydrogenase e1 component sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr SYD1_k127_7784632_16 518766.Rmar_2008 8.063e-66 258.0 COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1FJ1P@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 ko:K00128,ko:K00135 ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130 M00027,M00135 R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh SYD1_k127_8151582_7 552531.BIF_01972 2.944e-16 79.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CYY7@85004|Bifidobacteriales 201174|Actinobacteria J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 SYD1_k127_8151582_9 1121129.KB903374_gene542 6.674e-06 50.0 2DD50@1|root,2ZGIJ@2|Bacteria,4P8A2@976|Bacteroidetes,2FZIU@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - SYD1_k127_8151582_8 411467.BACCAP_00246 8.322e-12 71.0 2DPV4@1|root,333HA@2|Bacteria,1VH7Z@1239|Firmicutes,24SC2@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - SYD1_k127_8151582_4 269799.Gmet_0009 1.708e-47 194.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43C3Z@68525|delta/epsilon subdivisions,2X7EF@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Sensor histidine kinase, HAMP and PAS domain-containing - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,dCache_3,sCache_3_3 SYD1_k127_8151582_0 1499967.BAYZ01000148_gene1746 1.331e-132 456.0 COG0215@1|root,COG0215@2|Bacteria,2NNP0@2323|unclassified Bacteria 2|Bacteria J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECUMN_1333.ECUMN_0566,iJN746.PP_2905 DALR_2,tRNA-synt_1e,tRNA-synt_1g SYD1_k127_8151582_5 1184607.AUCHE_05_03030 2.966e-40 161.0 COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria,4F6NP@85018|Dermatophilaceae 201174|Actinobacteria M Mechanosensitive ion channel mscS - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel SYD1_k127_8151582_2 1379698.RBG1_1C00001G0842 5.404e-79 283.0 COG1181@1|root,COG1181@2|Bacteria,2NPB2@2323|unclassified Bacteria 2|Bacteria M Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N SYD1_k127_8151582_3 443143.GM18_4228 9.655e-51 185.0 COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2WJ67@28221|Deltaproteobacteria,43UN0@69541|Desulfuromonadales 28221|Deltaproteobacteria I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD,YgbB SYD1_k127_8151582_6 1907.SGLAU_15665 3.947e-37 159.0 COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria 201174|Actinobacteria I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD SYD1_k127_8151582_1 1123405.AUMM01000026_gene2160 4.447e-130 425.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,26NKP@186821|Sporolactobacillaceae 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI SYD1_k127_8190295_2 1144275.COCOR_03299 3.065e-185 607.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales 28221|Deltaproteobacteria KLTU Protein kinase domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase SYD1_k127_8190295_5 502025.Hoch_5408 2.83e-139 477.0 COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria,2YTZK@29|Myxococcales 28221|Deltaproteobacteria CE Peptidase family M1 domain pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,HEAT_2,Peptidase_M1 SYD1_k127_8190295_30 1123236.KB899377_gene272 1.644e-24 115.0 COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RSPM@1236|Gammaproteobacteria,465Z2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 SYD1_k127_8190295_11 649638.Trad_2700 2.435e-72 263.0 COG4221@1|root,COG4221@2|Bacteria,1WIDQ@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short SYD1_k127_8190295_28 1267533.KB906737_gene1567 4.857e-36 146.0 COG2945@1|root,COG2945@2|Bacteria,3Y35I@57723|Acidobacteria,2JIVZ@204432|Acidobacteriia 204432|Acidobacteriia - - - - - ko:K07018 - - - - ko00000 - - - Hydrolase_4 SYD1_k127_8190295_1 204669.Acid345_1786 6.238e-281 881.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,3Y34Y@57723|Acidobacteria,2JHQ9@204432|Acidobacteriia 204432|Acidobacteriia C Dehydrogenase E1 component - - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C SYD1_k127_8190295_15 684949.ATTJ01000001_gene1200 1.931e-60 214.0 2AYX9@1|root,31R2Z@2|Bacteria 2|Bacteria S DinB superfamily - - - - - - - - - - - - DinB_2 SYD1_k127_8190295_8 1242864.D187_000461 1.122e-88 322.0 COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,430H1@68525|delta/epsilon subdivisions,2WVZX@28221|Deltaproteobacteria,2YUWZ@29|Myxococcales 28221|Deltaproteobacteria L Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B,NUDIX SYD1_k127_8190295_22 530564.Psta_1177 1.878e-51 206.0 COG2040@1|root,COG2040@2|Bacteria,2J3GR@203682|Planctomycetes 203682|Planctomycetes H Homocysteine S-methyltransferase - - 2.1.1.10 ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 - R00650 RC00003,RC00035 ko00000,ko00001,ko01000 - - - S-methyl_trans SYD1_k127_8190295_14 1121918.ARWE01000001_gene2797 1.37e-62 236.0 COG1752@1|root,COG1752@2|Bacteria,1PHH5@1224|Proteobacteria,4379Q@68525|delta/epsilon subdivisions,2X2DQ@28221|Deltaproteobacteria,43UU3@69541|Desulfuromonadales 28221|Deltaproteobacteria S Patatin-like phospholipase - - - - - - - - - - - - Patatin SYD1_k127_8190295_26 215803.DB30_7213 1.666e-39 157.0 COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,43C29@68525|delta/epsilon subdivisions,2X7CU@28221|Deltaproteobacteria,2YV3W@29|Myxococcales 28221|Deltaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short SYD1_k127_8190295_4 1379698.RBG1_1C00001G0618 2.173e-160 530.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria 2|Bacteria EU peptidase S9 prolyl oligopeptidase active site yuxL - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 SYD1_k127_8190295_18 235909.GK1588 1.876e-54 216.0 COG3342@1|root,COG3342@2|Bacteria,1TS8U@1239|Firmicutes,4HBYK@91061|Bacilli,1WG5D@129337|Geobacillus 91061|Bacilli S Family of unknown function (DUF1028) - - - - - - - - - - - - DUF1028,PG_binding_2 SYD1_k127_8190295_17 1120972.AUMH01000013_gene2477 3.131e-55 211.0 COG3342@1|root,COG3342@2|Bacteria,1TS8U@1239|Firmicutes,4HBYK@91061|Bacilli,279NH@186823|Alicyclobacillaceae 91061|Bacilli S Family of unknown function (DUF1028) - - - - - - - - - - - - DUF1028,PG_binding_2 SYD1_k127_8190295_24 240015.ACP_0479 4.771e-46 181.0 COG3005@1|root,COG3005@2|Bacteria,3Y4BJ@57723|Acidobacteria,2JJ2B@204432|Acidobacteriia 204432|Acidobacteriia C Doubled CXXCH motif (Paired_CXXCH_1) - - - - - - - - - - - - Paired_CXXCH_1 SYD1_k127_8190295_19 552811.Dehly_0442 2.084e-54 204.0 COG3303@1|root,COG3303@2|Bacteria 2|Bacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - - - - - - - - - - Cytochrom_c3_2 SYD1_k127_8190295_9 671143.DAMO_0822 1.438e-78 295.0 COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria 2|Bacteria C Cytochrome c554 and c-prime - - - ko:K03620 ko02020,map02020 - - - ko00000,ko00001 - - - Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB SYD1_k127_8190295_6 671143.DAMO_0821 7.204e-131 428.0 COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria 2|Bacteria C Cytochrome b(N-terminal)/b6/petB petB - - ko:K00410,ko:K00412,ko:K02635,ko:K02637 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 - - ko00000,ko00001,ko00002,ko00194,ko03029 - - - Cytochrom_B_C,Cytochrom_C1,Cytochrome_B SYD1_k127_8190295_27 1379698.RBG1_1C00001G0781 5.902e-38 150.0 COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria 2|Bacteria C Rieske [2Fe-2S] domain petA - 1.10.2.2,1.10.9.1 ko:K00411,ko:K02636,ko:K03886 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - iAF987.Gmet_1922 CytB6-F_Fe-S,Rieske,UCR_Fe-S_N SYD1_k127_8190295_31 1501230.ET33_01050 5.954e-23 110.0 COG1805@1|root,COG1805@2|Bacteria,1UNWM@1239|Firmicutes,4IUT0@91061|Bacilli,277RJ@186822|Paenibacillaceae 91061|Bacilli C NQR2, RnfD, RnfE family - - - - - - - - - - - - NQR2_RnfD_RnfE SYD1_k127_8190295_3 330214.NIDE1172 1.195e-166 537.0 COG1805@1|root,COG4402@1|root,COG1805@2|Bacteria,COG4402@2|Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2330) nqrB GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 ko:K00347,ko:K21163 ko01059,ko01130,map01059,map01130 M00824 - - ko00000,ko00001,ko00002,ko01000 - - - DUF2330,NQR2_RnfD_RnfE SYD1_k127_8190295_7 330214.NIDE1172 6.752e-128 430.0 COG1805@1|root,COG4402@1|root,COG1805@2|Bacteria,COG4402@2|Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2330) nqrB GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 ko:K00347,ko:K21163 ko01059,ko01130,map01059,map01130 M00824 - - ko00000,ko00001,ko00002,ko01000 - - - DUF2330,NQR2_RnfD_RnfE SYD1_k127_8190295_32 755732.Fluta_0614 1.197e-13 79.0 2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia,2PBW4@246874|Cryomorphaceae 976|Bacteroidetes S Reeler domain - - - - - - - - - - - - Reeler SYD1_k127_8190295_34 945713.IALB_0781 4.334e-13 80.0 COG2867@1|root,COG2867@2|Bacteria 2|Bacteria I negative regulation of translational initiation - - - - - - - - - - - - Polyketide_cyc,Polyketide_cyc2,START SYD1_k127_8190295_16 1196323.ALKF01000201_gene2936 1.516e-56 221.0 COG0500@1|root,COG2226@2|Bacteria,1V0UT@1239|Firmicutes,4IT1S@91061|Bacilli,2777J@186822|Paenibacillaceae 91061|Bacilli Q sAM-dependent methyltransferases - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 SYD1_k127_8190295_21 1122221.JHVI01000004_gene147 1.348e-52 190.0 2CMS6@1|root,32SFE@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DinB_2 SYD1_k127_8190295_12 1168065.DOK_16163 4.989e-63 219.0 COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,1JB6E@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL SYD1_k127_8190295_36 1321778.HMPREF1982_02132 1.555e-07 59.0 2AFI1@1|root,315IM@2|Bacteria,1UUJJ@1239|Firmicutes,256YF@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - SYD1_k127_8190295_13 234267.Acid_2131 9.68e-63 238.0 COG1720@1|root,COG1720@2|Bacteria,3Y5T1@57723|Acidobacteria 57723|Acidobacteria S Uncharacterised protein family UPF0066 - - - - - - - - - - - - UPF0066 SYD1_k127_8190295_20 1303518.CCALI_01830 1.062e-52 208.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins rimL - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 SYD1_k127_8190295_10 269799.Gmet_0795 1.535e-72 252.0 COG0500@1|root,COG0500@2|Bacteria,1QW0F@1224|Proteobacteria,43C56@68525|delta/epsilon subdivisions,2X7FJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 SYD1_k127_8190295_0 335543.Sfum_0929 2.833e-299 953.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MQUW@213462|Syntrophobacterales 28221|Deltaproteobacteria L DNA polymerase III alpha subunit - - 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon SYD1_k127_8190295_33 1120949.KB903303_gene6799 3.905e-13 82.0 COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4D9C3@85008|Micromonosporales 201174|Actinobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinP - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH SYD1_k127_8190295_29 1380394.JADL01000007_gene4688 6.658e-30 121.0 COG1359@1|root,COG1359@2|Bacteria 2|Bacteria S Antibiotic biosynthesis monooxygenase lsrG - 5.3.1.32 ko:K11530 ko02024,map02024 - - - ko00000,ko00001,ko01000 - - - ABM SYD1_k127_8190295_23 1379698.RBG1_1C00001G0328 2.821e-47 181.0 2C7E0@1|root,330TX@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_8190295_37 886293.Sinac_4727 5.658e-06 49.0 COG0346@1|root,COG0346@2|Bacteria,2J13G@203682|Planctomycetes 203682|Planctomycetes E Glyoxalase-like domain - - - ko:K07032 - - - - ko00000 - - - Glyoxalase SYD1_k127_8190295_25 335543.Sfum_0927 3.582e-43 161.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42PAH@68525|delta/epsilon subdivisions,2WKSM@28221|Deltaproteobacteria,2MS4X@213462|Syntrophobacterales 28221|Deltaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356,ko:K03503 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 SYD1_k127_8196735_18 644966.Tmar_0085 1.056e-47 183.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,3WCJ0@538999|Clostridiales incertae sedis 186801|Clostridia J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA - 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD SYD1_k127_8196735_17 370438.PTH_0070 1.272e-52 213.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,260P1@186807|Peptococcaceae 186801|Clostridia L TIGRFAM hydrolase, TatD family tatD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase SYD1_k127_8196735_4 643648.Slip_0054 4.654e-148 486.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,42JKJ@68298|Syntrophomonadaceae 186801|Clostridia J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind SYD1_k127_8196735_11 880073.Calab_1952 2.585e-68 259.0 COG1774@1|root,COG1774@2|Bacteria,2NPEB@2323|unclassified Bacteria 2|Bacteria S PSP1 C-terminal conserved region yaaT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - PSP1 SYD1_k127_8196735_22 518766.Rmar_2254 1.316e-37 156.0 COG2812@1|root,COG2812@2|Bacteria,4PKEA@976|Bacteroidetes,1FJ1I@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes L DNA polymerase III, delta subunit - - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2 SYD1_k127_8196735_16 1379698.RBG1_1C00001G0315 2.367e-53 213.0 COG4942@1|root,COG4942@2|Bacteria,2NPDY@2323|unclassified Bacteria 2|Bacteria D Peptidase family M23 envC GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 SYD1_k127_8196735_24 861299.J421_3760 2.126e-20 105.0 COG2177@1|root,COG2177@2|Bacteria,1ZTDR@142182|Gemmatimonadetes 142182|Gemmatimonadetes D Part of the ABC transporter FtsEX involved in - - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - - SYD1_k127_8196735_15 264732.Moth_0244 2.241e-54 200.0 COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,42EW3@68295|Thermoanaerobacterales 186801|Clostridia D TIGRFAM Cell division ATP-binding protein FtsE ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran SYD1_k127_8196735_12 880072.Desac_2139 2.024e-67 242.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria,2MQFD@213462|Syntrophobacterales 28221|Deltaproteobacteria H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262,1.1.1.408,1.1.1.409 ko:K00097,ko:K22024 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA SYD1_k127_8196735_21 667632.KB890217_gene4846 4.932e-40 166.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria,1K1ZZ@119060|Burkholderiaceae 28216|Betaproteobacteria M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N SYD1_k127_8196735_29 588932.JHOF01000017_gene2490 2.971e-09 70.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria,2KG5E@204458|Caulobacterales 204458|Caulobacterales M peptidylprolyl isomerase - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3 SYD1_k127_8196735_2 1121468.AUBR01000069_gene1116 4.6e-255 826.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,42EQJ@68295|Thermoanaerobacterales 186801|Clostridia L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF SYD1_k127_8196735_23 1242864.D187_001185 8.18e-27 128.0 COG2304@1|root,COG2304@2|Bacteria,1NX8F@1224|Proteobacteria,430QD@68525|delta/epsilon subdivisions,2WVNR@28221|Deltaproteobacteria,2YW4W@29|Myxococcales 28221|Deltaproteobacteria S Aerotolerance regulator N-terminal - - - - - - - - - - - - BatA,VWA_2 SYD1_k127_8196735_7 1379698.RBG1_1C00001G0202 2.82e-96 323.0 COG1721@1|root,COG1721@2|Bacteria,2NP6B@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 SYD1_k127_8196735_5 1379698.RBG1_1C00001G0201 5.943e-131 427.0 COG0714@1|root,COG0714@2|Bacteria,2NNV8@2323|unclassified Bacteria 2|Bacteria O ATPase family associated with various cellular activities (AAA) moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 SYD1_k127_8196735_14 644282.Deba_1076 6.562e-63 227.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc SYD1_k127_8196735_8 697281.Mahau_2951 6.291e-92 310.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,42F5R@68295|Thermoanaerobacterales 186801|Clostridia D PFAM Cobyrinic acid a,c-diamide synthase soj - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 SYD1_k127_8196735_25 1049564.TevJSym_aq00370 1.277e-19 97.0 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,1J6CC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB SYD1_k127_8196735_3 289376.THEYE_A0585 1.397e-177 595.0 COG0445@1|root,COG0445@2|Bacteria,3J0E9@40117|Nitrospirae 40117|Nitrospirae D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc SYD1_k127_8196735_9 552398.HMPREF0866_02837 6.457e-81 287.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,3WGHG@541000|Ruminococcaceae 186801|Clostridia S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N SYD1_k127_8196735_27 1167006.UWK_01750 7.349e-15 85.0 COG1847@1|root,COG1847@2|Bacteria,1RB1P@1224|Proteobacteria,42QPK@68525|delta/epsilon subdivisions,2WN58@28221|Deltaproteobacteria,2MJJC@213118|Desulfobacterales 28221|Deltaproteobacteria S PFAM single-stranded nucleic acid binding R3H - - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H SYD1_k127_8196735_13 1379698.RBG1_1C00001G0260 2.348e-66 248.0 COG0706@1|root,COG0706@2|Bacteria,2NP6C@2323|unclassified Bacteria 2|Bacteria U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas SYD1_k127_8196735_26 62928.azo3990 4.63e-19 94.0 COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,2KX78@206389|Rhodocyclales 206389|Rhodocyclales S Could be involved in insertion of integral membrane proteins into the membrane - - - ko:K08998 - - - - ko00000 - - - Haemolytic SYD1_k127_8196735_31 1410630.JNKP01000004_gene424 2.534e-05 52.0 COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,27P14@186928|unclassified Lachnospiraceae 186801|Clostridia J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P SYD1_k127_8196735_28 1122164.JHWF01000003_gene2152 1.41e-10 66.0 COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria,1JF92@118969|Legionellales 118969|Legionellales J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 SYD1_k127_8196735_6 1131462.DCF50_p1 9.778e-128 422.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,260P2@186807|Peptococcaceae 186801|Clostridia L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N SYD1_k127_8196735_10 861299.J421_1072 8.813e-80 280.0 COG0592@1|root,COG0592@2|Bacteria,1ZT22@142182|Gemmatimonadetes 142182|Gemmatimonadetes L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria - - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_3 SYD1_k127_8196735_19 861299.J421_2731 1.379e-43 174.0 COG1195@1|root,COG1195@2|Bacteria,1ZSRU@142182|Gemmatimonadetes 142182|Gemmatimonadetes L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF - - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N SYD1_k127_8196735_30 1121377.KB906398_gene2409 1.871e-07 62.0 COG5512@1|root,COG5512@2|Bacteria,1WIYS@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 SYD1_k127_8196735_1 635013.TherJR_0008 1.706e-290 904.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,260WQ@186807|Peptococcaceae 186801|Clostridia L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim SYD1_k127_8196735_0 1191523.MROS_1041 0.0 1033.0 COG0188@1|root,COG0188@2|Bacteria 2|Bacteria L DNA topoisomerase II activity gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV SYD1_k127_8196735_20 379066.GAU_1881 5.082e-41 155.0 COG2344@1|root,COG2344@2|Bacteria,1ZTJV@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N SYD1_k127_8197361_4 743719.PaelaDRAFT_0567 4.7e-16 85.0 COG2318@1|root,COG2318@2|Bacteria,1V8MI@1239|Firmicutes,4HJT7@91061|Bacilli,26XGY@186822|Paenibacillaceae 91061|Bacilli S DinB family - - - - - - - - - - - - DinB SYD1_k127_8197361_3 204669.Acid345_0949 4.387e-33 133.0 2EBAA@1|root,335AW@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - RsbRD_N SYD1_k127_8197361_1 234267.Acid_7636 5.116e-179 591.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria 57723|Acidobacteria KLTU Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40,Pkinase SYD1_k127_8197361_2 290397.Adeh_2107 5.708e-93 319.0 COG0500@1|root,COG2226@2|Bacteria,1R98E@1224|Proteobacteria,43847@68525|delta/epsilon subdivisions,2X3E4@28221|Deltaproteobacteria,2YVN5@29|Myxococcales 28221|Deltaproteobacteria Q Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 SYD1_k127_8197361_0 234267.Acid_5940 1.678e-218 707.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria 57723|Acidobacteria KLTU WD40 domain protein beta Propeller - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase SYD1_k127_8213646_29 631454.N177_3114 1.722e-30 123.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 SYD1_k127_8213646_12 517418.Ctha_0364 2.491e-68 252.0 COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1FEH6@1090|Chlorobi 1090|Chlorobi GM Bacterial sugar transferase - - - - - - - - - - - - Bac_transf,CoA_binding_3 SYD1_k127_8213646_8 204669.Acid345_1079 1.335e-103 347.0 COG0673@1|root,COG0673@2|Bacteria,3Y486@57723|Acidobacteria,2JHJI@204432|Acidobacteriia 204432|Acidobacteriia S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA SYD1_k127_8213646_15 35754.JNYJ01000038_gene4917 6.318e-62 228.0 COG0110@1|root,COG0110@2|Bacteria,2H5M0@201174|Actinobacteria,4DF0N@85008|Micromonosporales 201174|Actinobacteria S Hexapeptide repeat of succinyl-transferase - - - - - - - - - - - - Hexapep SYD1_k127_8213646_43 403833.Pmob_0995 5.954e-06 59.0 28MEQ@1|root,2ZASC@2|Bacteria,2GCZS@200918|Thermotogae 200918|Thermotogae - - - - - - - - - - - - - - - SYD1_k127_8213646_16 1379698.RBG1_1C00001G1726 5.114e-60 228.0 29YZ1@1|root,30KVZ@2|Bacteria,2NRNQ@2323|unclassified Bacteria 2|Bacteria S Capsule assembly protein Wzi - - - - - - - - - - - - Caps_assemb_Wzi SYD1_k127_8213646_40 252305.OB2597_16030 1.784e-06 58.0 COG1572@1|root,COG1864@1|root,COG3209@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG3209@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1QW4H@1224|Proteobacteria 1224|Proteobacteria M Rhs Family - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Autotransporter,Big_3_2,Big_3_5,DUF4082,DUF4347,He_PIG SYD1_k127_8213646_27 29581.BW37_03778 6.401e-34 146.0 COG0454@1|root,COG1853@1|root,COG0456@2|Bacteria,COG1853@2|Bacteria,1NB1B@1224|Proteobacteria,2VQ0V@28216|Betaproteobacteria,47313@75682|Oxalobacteraceae 28216|Betaproteobacteria K Flavin reductase like domain flr - - - - - - - - - - - Flavin_Reduct SYD1_k127_8213646_21 266117.Rxyl_2933 1.837e-50 199.0 COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria 201174|Actinobacteria S CHAD domain containing protein - - - - - - - - - - - - CHAD,CYTH SYD1_k127_8213646_31 886293.Sinac_5337 2.71e-25 111.0 COG2062@1|root,COG2062@2|Bacteria,2J1GK@203682|Planctomycetes 203682|Planctomycetes T phosphohistidine phosphatase, SixA - - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 SYD1_k127_8213646_33 335543.Sfum_1327 9.833e-21 100.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2MRPA@213462|Syntrophobacterales 28221|Deltaproteobacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SYD1_k127_8213646_10 448385.sce5606 1.699e-94 331.0 COG0248@1|root,COG2206@1|root,COG0248@2|Bacteria,COG2206@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WN60@28221|Deltaproteobacteria,2YUZ0@29|Myxococcales 28221|Deltaproteobacteria FP Ppx/GppA phosphatase family gppA-2 - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA SYD1_k127_8213646_9 530564.Psta_3550 1.135e-97 338.0 COG0248@1|root,COG0248@2|Bacteria,2IYSV@203682|Planctomycetes 203682|Planctomycetes FP Ppx GppA phosphatase - - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA SYD1_k127_8213646_41 28072.Nos7524_4621 2.303e-06 62.0 COG0823@1|root,COG2304@1|root,COG3209@1|root,COG3210@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1GQ0G@1117|Cyanobacteria,1HN8U@1161|Nostocales 1117|Cyanobacteria MU Dystroglycan-type cadherin-like domains. - - - - - - - - - - - - Cadherin,He_PIG,RHS_repeat SYD1_k127_8213646_17 1463887.KL590085_gene537 8.603e-60 237.0 COG1361@1|root,COG2706@1|root,COG1361@2|Bacteria,COG2706@2|Bacteria 2|Bacteria G 6-phosphogluconolactonase activity - - - - - - - - - - - - DUF11,VCBS SYD1_k127_8213646_39 880073.Calab_1858 1.009e-06 63.0 COG1361@1|root,COG4447@1|root,COG4935@1|root,COG1361@2|Bacteria,COG4447@2|Bacteria,COG4935@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - CHU_C,FlgD_ig,TM_helix SYD1_k127_8213646_24 404589.Anae109_3400 3.482e-49 192.0 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - HNH,HNH_4 SYD1_k127_8213646_5 313606.M23134_00387 5.756e-156 518.0 COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia 976|Bacteroidetes P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoA,FeoB_C,FeoB_N,Gate SYD1_k127_8213646_37 391625.PPSIR1_32879 6.77e-12 76.0 COG1918@1|root,COG1918@2|Bacteria,1Q29B@1224|Proteobacteria,42VSV@68525|delta/epsilon subdivisions,2WS7A@28221|Deltaproteobacteria,2Z28N@29|Myxococcales 28221|Deltaproteobacteria P FeoA - - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA SYD1_k127_8213646_34 1121405.dsmv_1854 5.723e-18 91.0 COG1321@1|root,COG1321@2|Bacteria,1RHIK@1224|Proteobacteria,42SAD@68525|delta/epsilon subdivisions,2WPIC@28221|Deltaproteobacteria,2MKI7@213118|Desulfobacterales 28221|Deltaproteobacteria K PFAM iron dependent repressor - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA SYD1_k127_8213646_3 498761.HM1_0232 4.285e-181 593.0 COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia 186801|Clostridia P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N SYD1_k127_8213646_25 1033802.SSPSH_000666 1.088e-48 181.0 2A4CF@1|root,30SY3@2|Bacteria,1RFXP@1224|Proteobacteria,1SP3W@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SYD1_k127_8213646_2 926566.Terro_1107 3.608e-252 827.0 COG0474@1|root,COG0474@2|Bacteria,3Y3ZX@57723|Acidobacteria,2JIQJ@204432|Acidobacteriia 204432|Acidobacteriia P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.6,3.6.3.8 ko:K01535,ko:K01537 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.2,3.A.3.3 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase SYD1_k127_8213646_44 861299.J421_3481 6.755e-06 59.0 2DBDX@1|root,2Z8PX@2|Bacteria 2|Bacteria S Capsule assembly protein Wzi - - - - - - - - - - - - Caps_assemb_Wzi SYD1_k127_8213646_35 1267535.KB906767_gene4539 4.527e-16 91.0 COG2823@1|root,COG2823@2|Bacteria,3Y7ZV@57723|Acidobacteria 57723|Acidobacteria S Periplasmic or secreted lipoprotein - - - - - - - - - - - - - SYD1_k127_8213646_20 1379698.RBG1_1C00001G0252 5.347e-51 189.0 COG2323@1|root,COG2323@2|Bacteria,2NR09@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 SYD1_k127_8213646_6 1009370.ALO_13819 6.739e-116 385.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H27Q@909932|Negativicutes 909932|Negativicutes G M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 SYD1_k127_8213646_23 604331.AUHY01000022_gene1541 7.173e-50 199.0 COG0580@1|root,COG0580@2|Bacteria,1WKA2@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G Belongs to the MIP aquaporin (TC 1.A.8) family - - - ko:K06188 - - - - ko00000,ko02000 1.A.8 - - MIP SYD1_k127_8213646_4 574087.Acear_0203 3.568e-179 597.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1TQJM@1239|Firmicutes,24CFC@186801|Clostridia 186801|Clostridia C TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit glpC - 1.1.5.3 ko:K00113 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - CCG,Fer4_8 SYD1_k127_8213646_38 1249975.JQLP01000005_gene769 8.848e-07 60.0 COG4244@1|root,COG4244@2|Bacteria,4PBXG@976|Bacteroidetes,1ICUY@117743|Flavobacteriia,2P7RX@244698|Gillisia 976|Bacteroidetes S Membrane - - - - - - - - - - - - - SYD1_k127_8213646_18 861299.J421_3685 1.781e-57 205.0 COG0231@1|root,COG0231@2|Bacteria,1ZT2N@142182|Gemmatimonadetes 142182|Gemmatimonadetes J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C SYD1_k127_8213646_11 485913.Krac_10280 1.262e-70 248.0 COG0596@1|root,COG0596@2|Bacteria,2G6VQ@200795|Chloroflexi 2|Bacteria S PFAM alpha beta hydrolase fold MA20_20400 - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1,Abhydrolase_6 SYD1_k127_8213646_19 1157490.EL26_19490 5.512e-53 206.0 COG0492@1|root,COG0492@2|Bacteria,1V4WN@1239|Firmicutes,4HHA8@91061|Bacilli,278DV@186823|Alicyclobacillaceae 91061|Bacilli C Pyridine nucleotide-disulphide oxidoreductase - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 SYD1_k127_8213646_30 1382315.JPOI01000001_gene919 1.289e-26 118.0 COG1216@1|root,COG1216@2|Bacteria,1TP40@1239|Firmicutes,4HDDN@91061|Bacilli,1WEMA@129337|Geobacillus 91061|Bacilli S Glycosyltransferase like family 2 ywdF GO:0003674,GO:0003824,GO:0016740,GO:0016757 - - - - - - - - - - Glycos_transf_2 SYD1_k127_8213646_32 380749.HY04AAS1_0018 2.854e-22 110.0 COG0302@1|root,COG0302@2|Bacteria,2G40B@200783|Aquificae 200783|Aquificae H GTP cyclohydrolase folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI SYD1_k127_8213646_14 861299.J421_2433 1.052e-64 227.0 COG2316@1|root,COG2316@2|Bacteria,1ZTH6@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - - - - - - - - - - HD SYD1_k127_8213646_42 743525.TSC_c13210 3.737e-06 59.0 28N2E@1|root,2ZB88@2|Bacteria,1WIR8@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus - - - - - - - - - - - - - - - SYD1_k127_8213646_0 1121472.AQWN01000006_gene1706 2.713e-307 966.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,25ZYN@186807|Peptococcaceae 186801|Clostridia J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 SYD1_k127_8213646_7 1379698.RBG1_1C00001G0415 1.207e-106 385.0 COG5316@1|root,COG5316@2|Bacteria,2NPBR@2323|unclassified Bacteria 2|Bacteria S Domain of unknown function (DUF4139) - - - - - - - - - - - - DUF4139 SYD1_k127_8213646_1 880073.Calab_3212 1.104e-260 846.0 COG0556@1|root,COG0556@2|Bacteria,2NNPM@2323|unclassified Bacteria 2|Bacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB SYD1_k127_8213646_13 383372.Rcas_1005 1.953e-66 239.0 COG0157@1|root,COG0157@2|Bacteria,2G6GJ@200795|Chloroflexi,375H1@32061|Chloroflexia 32061|Chloroflexia H Belongs to the NadC ModD family - - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N SYD1_k127_8213646_26 1089553.Tph_c26600 3.059e-38 153.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,42F0N@68295|Thermoanaerobacterales 186801|Clostridia H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 SYD1_k127_8213646_22 203119.Cthe_0450 3.921e-50 194.0 COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3WJ07@541000|Ruminococcaceae 186801|Clostridia K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone SYD1_k127_8213646_28 1111454.HMPREF1250_1549 1.041e-31 137.0 COG0805@1|root,COG0805@2|Bacteria,1U7N7@1239|Firmicutes,4H269@909932|Negativicutes 909932|Negativicutes U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC SYD1_k127_8213646_36 1192034.CAP_5889 1.662e-15 89.0 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,42MVZ@68525|delta/epsilon subdivisions,2WJ3N@28221|Deltaproteobacteria,2YTUR@29|Myxococcales 28221|Deltaproteobacteria F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1986 Pan_kinase SYD1_k127_8319594_4 867903.ThesuDRAFT_01682 4.674e-61 216.0 COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,3WCER@538999|Clostridiales incertae sedis 186801|Clostridia L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N SYD1_k127_8319594_1 648996.Theam_1729 5.74e-104 352.0 COG0809@1|root,COG0809@2|Bacteria,2G3KG@200783|Aquificae 200783|Aquificae J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth SYD1_k127_8319594_9 667632.KB890164_gene2087 5.519e-07 57.0 COG1886@1|root,COG1886@2|Bacteria,1PYS5@1224|Proteobacteria,2WDWU@28216|Betaproteobacteria,1KB5P@119060|Burkholderiaceae 28216|Betaproteobacteria NU Type III flagellar switch regulator (C-ring) FliN C-term - - - - - - - - - - - - FliMN_C SYD1_k127_8319594_2 635013.TherJR_1520 8.204e-62 225.0 COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,24AIN@186801|Clostridia,26151@186807|Peptococcaceae 186801|Clostridia D Belongs to the ParA family flhG - - ko:K04562 - - - - ko00000,ko02035 - - - AAA_31,CbiA,ParA SYD1_k127_8319594_3 1480694.DC28_02445 4.113e-61 219.0 COG1191@1|root,COG1191@2|Bacteria,2J5RA@203691|Spirochaetes 203691|Spirochaetes K Belongs to the sigma-70 factor family fliA - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 SYD1_k127_8319594_6 589865.DaAHT2_0261 2.192e-43 180.0 COG1639@1|root,COG1639@2|Bacteria,1R8H3@1224|Proteobacteria,42PER@68525|delta/epsilon subdivisions,2X29A@28221|Deltaproteobacteria,2MNF5@213118|Desulfobacterales 28221|Deltaproteobacteria T HDOD domain - - - - - - - - - - - - HDOD SYD1_k127_8319594_7 635013.TherJR_2805 5.291e-26 122.0 COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1TQIK@1239|Firmicutes,249Y6@186801|Clostridia,267E8@186807|Peptococcaceae 186801|Clostridia T TIGRFAM Diguanylate cyclase - - - - - - - - - - - - GAF,GAF_2,GGDEF SYD1_k127_8319594_5 909663.KI867150_gene2881 1.186e-58 226.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42QJF@68525|delta/epsilon subdivisions,2WJ9D@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_4,Response_reg SYD1_k127_8319594_0 1118054.CAGW01000043_gene1127 8.71e-117 387.0 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli,26R2K@186822|Paenibacillaceae 91061|Bacilli M Belongs to the UDP-N-acetylglucosamine 2-epimerase family mnaA - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - iSB619.SA_RS11005 Epimerase_2 SYD1_k127_8319594_8 755732.Fluta_0614 2.464e-09 68.0 2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia,2PBW4@246874|Cryomorphaceae 976|Bacteroidetes S Reeler domain - - - - - - - - - - - - Reeler SYD1_k127_8367319_1 290397.Adeh_0969 3.533e-39 150.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,42TN9@68525|delta/epsilon subdivisions,2WRG0@28221|Deltaproteobacteria,2Z0S2@29|Myxococcales 28221|Deltaproteobacteria H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt - 2.1.1.63 ko:K00567,ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N SYD1_k127_8367319_0 1232410.KI421414_gene2894 5.399e-46 175.0 COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,42STM@68525|delta/epsilon subdivisions,2WPAD@28221|Deltaproteobacteria,43T26@69541|Desulfuromonadales 28221|Deltaproteobacteria S Peptidase family M50 - - - - - - - - - - - - Peptidase_M50 SYD1_k127_8367319_3 1232410.KI421413_gene579 2.489e-18 86.0 COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,42XRW@68525|delta/epsilon subdivisions,2WT0E@28221|Deltaproteobacteria,43VPM@69541|Desulfuromonadales 28221|Deltaproteobacteria S Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase yacG - - ko:K09862 - - - - ko00000 - - - YacG SYD1_k127_8367319_2 330214.NIDE0855 5.695e-25 115.0 COG1392@1|root,COG1392@2|Bacteria 2|Bacteria P Protein of unknown function DUF47 MA20_27875 - - ko:K02039,ko:K07220 - - - - ko00000 - - - PhoU_div SYD1_k127_8401073_1 1123023.JIAI01000033_gene4187 3.371e-99 331.0 COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,4E0VQ@85010|Pseudonocardiales 201174|Actinobacteria S alcohol dehydrogenase adhA - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N SYD1_k127_8401073_5 1125863.JAFN01000001_gene2446 1.199e-59 215.0 COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,42NZQ@68525|delta/epsilon subdivisions,2WMCW@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Enoyl-CoA hydratase/isomerase - - 4.2.1.100 ko:K07537 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05597 RC03168 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 SYD1_k127_8401073_0 402881.Plav_1564 1.612e-101 353.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,1JPZN@119043|Rhodobiaceae 28211|Alphaproteobacteria EH chorismate binding enzyme pabB - 2.6.1.85,4.1.3.27 ko:K01657,ko:K01665 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind SYD1_k127_8401073_2 1382306.JNIM01000001_gene332 6.307e-98 332.0 COG1788@1|root,COG1788@2|Bacteria,2G6IM@200795|Chloroflexi 200795|Chloroflexi I Coenzyme A transferase - - 2.8.3.12 ko:K01039 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans SYD1_k127_8401073_8 1173026.Glo7428_3186 2.256e-33 140.0 COG4891@1|root,COG4891@2|Bacteria,1G7CI@1117|Cyanobacteria 1117|Cyanobacteria S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 SYD1_k127_8401073_4 351160.RRC418 2.645e-69 252.0 COG0477@1|root,arCOG00132@2157|Archaea,2XW9U@28890|Euryarchaeota 28890|Euryarchaeota G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_1_like,MFS_3 SYD1_k127_8401073_6 1380394.JADL01000011_gene3820 4.288e-55 198.0 COG1764@1|root,COG1764@2|Bacteria,1RHVR@1224|Proteobacteria,2VG83@28211|Alphaproteobacteria,2JTM8@204441|Rhodospirillales 204441|Rhodospirillales O OsmC-like protein - - - - - - - - - - - - OsmC SYD1_k127_8401073_3 1379698.RBG1_1C00001G1834 2.31e-80 277.0 COG1028@1|root,COG1028@2|Bacteria,2NQVI@2323|unclassified Bacteria 2|Bacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.3.1.104 ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SYD1_k127_8401073_7 1125863.JAFN01000001_gene2230 7.763e-54 205.0 COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,42RB0@68525|delta/epsilon subdivisions,2WN8G@28221|Deltaproteobacteria 28221|Deltaproteobacteria S membrane - - - - - - - - - - - - - SYD1_k127_8412478_2 401053.AciPR4_2460 1.871e-13 80.0 COG4319@1|root,COG4319@2|Bacteria,3Y5FP@57723|Acidobacteria,2JN7M@204432|Acidobacteriia 204432|Acidobacteriia S SnoaL-like domain - - - - - - - - - - - - DUF4440 SYD1_k127_8412478_1 945713.IALB_0468 3.894e-32 132.0 2BN55@1|root,33HC1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_8412478_0 497964.CfE428DRAFT_4035 6.891e-130 427.0 COG0019@1|root,COG0019@2|Bacteria 2|Bacteria E diaminopimelate decarboxylase activity lysA GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4,4.1.1.20 ko:K01586,ko:K12526 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00525,M00526,M00527 R00451,R00480 RC00002,RC00043,RC00299 ko00000,ko00001,ko00002,ko01000 - - iG2583_1286.G2583_3495 AA_kinase,Orn_Arg_deC_N,Orn_DAP_Arg_deC SYD1_k127_8412478_4 323848.Nmul_A2020 2.862e-07 63.0 COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria,2VWW5@28216|Betaproteobacteria 28216|Betaproteobacteria S HAF family - - - - - - - - - - - - VPEP SYD1_k127_8453201_0 861299.J421_5836 1.469e-129 443.0 COG0515@1|root,COG0515@2|Bacteria 861299.J421_5836|- KLT protein kinase activity - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - - SYD1_k127_8453201_22 861299.J421_4420 2.181e-12 80.0 COG0296@1|root,COG0296@2|Bacteria,1ZUZV@142182|Gemmatimonadetes 142182|Gemmatimonadetes G Glycogen recognition site of AMP-activated protein kinase - - - - - - - - - - - - - SYD1_k127_8453201_21 330214.NIDE1608 8.825e-19 94.0 COG0296@1|root,COG0296@2|Bacteria 2|Bacteria G 1,4-alpha-glucan branching enzyme activity - - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48 SYD1_k127_8453201_16 292459.STH181 8.88e-29 128.0 COG1595@1|root,COG1595@2|Bacteria,1VBIF@1239|Firmicutes,24P38@186801|Clostridia 186801|Clostridia K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SYD1_k127_8453201_1 1499967.BAYZ01000159_gene546 1.549e-124 436.0 2EYYT@1|root,33S5J@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_8453201_19 100226.SCO6525 5.052e-22 110.0 COG2220@1|root,COG2220@2|Bacteria,2GN98@201174|Actinobacteria 201174|Actinobacteria S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 SYD1_k127_8453201_18 1267535.KB906767_gene1002 2.117e-23 115.0 COG2365@1|root,COG2365@2|Bacteria,3Y8BW@57723|Acidobacteria 57723|Acidobacteria T Tyrosine phosphatase family - - - - - - - - - - - - Y_phosphatase2 SYD1_k127_8453201_8 56107.Cylst_5525 3.111e-62 228.0 COG3173@1|root,COG3173@2|Bacteria 2|Bacteria S very-long-chain-acyl-CoA dehydrogenase activity - - - - - - - - - - - - APH SYD1_k127_8453201_3 234267.Acid_6389 6.103e-89 322.0 COG4403@1|root,COG4403@2|Bacteria 2|Bacteria V Lanthionine synthetase C family protein - - - - - - - - - - - - DUF4135,LANC_like,VCBS SYD1_k127_8453201_5 234267.Acid_3593 1.029e-79 298.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria 2|Bacteria KU WD40 domain protein beta Propeller - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase,WD40 SYD1_k127_8453201_14 1449347.JQLN01000006_gene3088 1.209e-30 132.0 COG0823@1|root,COG3468@1|root,COG0823@2|Bacteria,COG3468@2|Bacteria 2|Bacteria MU cell adhesion - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - PD40,REJ,TIG,VWA,YbaB_DNA_bd SYD1_k127_8453201_2 272134.KB731326_gene299 2.658e-120 407.0 COG0661@1|root,COG0661@2|Bacteria,1G0X9@1117|Cyanobacteria,1H92B@1150|Oscillatoriales 1117|Cyanobacteria S Unusual protein kinase - - - - - - - - - - - - ABC1 SYD1_k127_8453201_17 1356852.N008_08475 3.171e-24 119.0 COG0204@1|root,COG0204@2|Bacteria,4NK8Z@976|Bacteroidetes,47NT5@768503|Cytophagia 976|Bacteroidetes I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase SYD1_k127_8453201_13 235985.BBPN01000034_gene851 6.289e-37 149.0 COG0726@1|root,COG0726@2|Bacteria,2GN6G@201174|Actinobacteria,2NIDV@228398|Streptacidiphilus 201174|Actinobacteria G Polysaccharide deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 SYD1_k127_8453201_11 1094980.Mpsy_3144 1.329e-43 175.0 COG4803@1|root,arCOG09748@1|root,arCOG05227@2157|Archaea,arCOG09748@2157|Archaea 2157|Archaea S Protein of unknown function (DUF1269) - - - ko:K03316 - - - - ko00000 2.A.36 - - - SYD1_k127_8453201_9 1231190.NA8A_23839 7.088e-59 208.0 COG0662@1|root,COG0662@2|Bacteria,1RJ7D@1224|Proteobacteria,2UAG4@28211|Alphaproteobacteria,43PJI@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 SYD1_k127_8453201_12 404589.Anae109_3322 2.964e-43 171.0 COG3247@1|root,COG3247@2|Bacteria,1RH69@1224|Proteobacteria,433TY@68525|delta/epsilon subdivisions,2WWM0@28221|Deltaproteobacteria,2YVY5@29|Myxococcales 28221|Deltaproteobacteria S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 SYD1_k127_8453201_4 1121918.ARWE01000001_gene3123 5.437e-84 293.0 COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,42UMC@68525|delta/epsilon subdivisions,2WQJQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S VIT family - - - - - - - - - - - - VIT1 SYD1_k127_8453201_23 886293.Sinac_2959 2.902e-11 75.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Glyoxalase,Methyltransf_11,Methyltransf_25 SYD1_k127_8453201_15 661478.OP10G_1144 1.564e-29 130.0 COG3358@1|root,COG3358@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1684) - - - ko:K09164 - - - - ko00000 - - - DUF1684 SYD1_k127_8453201_20 1463881.KL591008_gene1900 3.461e-20 104.0 COG2220@1|root,COG2220@2|Bacteria,2GN98@201174|Actinobacteria 201174|Actinobacteria S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 SYD1_k127_8453201_6 1318628.MARLIPOL_12500 2.003e-71 259.0 COG2982@1|root,COG2982@2|Bacteria,1NARH@1224|Proteobacteria,1SE5J@1236|Gammaproteobacteria,468PT@72275|Alteromonadaceae 1236|Gammaproteobacteria M Protein involved in outer membrane biogenesis - - - - - - - - - - - - AsmA,AsmA_2 SYD1_k127_8453201_7 768066.HELO_3947 4.461e-68 252.0 COG0183@1|root,COG0183@2|Bacteria,1MXYM@1224|Proteobacteria,1S0V9@1236|Gammaproteobacteria,1XN9H@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the thiolase family - - - - - - - - - - - - Thiolase_C,Thiolase_N SYD1_k127_8453201_10 391625.PPSIR1_09331 1.033e-50 203.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria 2|Bacteria I 3-hydroxyacyl-CoA dehydrogenase paaH GO:0003674,GO:0003824,GO:0003857,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0008691,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - iECO103_1326.ECO103_1532,iJN746.PP_3282 3HCDH,3HCDH_N SYD1_k127_8455600_7 682795.AciX8_1998 6.516e-137 459.0 COG0793@1|root,COG0793@2|Bacteria,3Y6R0@57723|Acidobacteria 57723|Acidobacteria M Peptidase family S41 - - - - - - - - - - - - Peptidase_S41 SYD1_k127_8455600_17 222534.KB893670_gene3651 3.391e-53 205.0 COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4ERCV@85013|Frankiales 201174|Actinobacteria G PFAM Inositol monophosphatase hisN - 3.1.3.15,3.1.3.25 ko:K01092,ko:K05602 ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070 M00026,M00131 R01185,R01186,R01187,R03013 RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P SYD1_k127_8455600_18 1234364.AMSF01000024_gene3817 1.124e-50 188.0 COG1670@1|root,COG1670@2|Bacteria,1RKKE@1224|Proteobacteria,1S47R@1236|Gammaproteobacteria,1X7VY@135614|Xanthomonadales 135614|Xanthomonadales J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 SYD1_k127_8455600_16 1303518.CCALI_02446 9.6e-62 221.0 COG1853@1|root,COG1853@2|Bacteria 2|Bacteria S FMN binding - - - - - - - - - - - - Flavin_Reduct SYD1_k127_8455600_5 1157490.EL26_09005 2.078e-160 531.0 COG3508@1|root,COG3508@2|Bacteria,1UYZ0@1239|Firmicutes,4HCCC@91061|Bacilli,2785R@186823|Alicyclobacillaceae 91061|Bacilli Q homogentisate 1,2-dioxygenase - - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA SYD1_k127_8455600_12 1117108.PAALTS15_01020 3.805e-97 331.0 COG0179@1|root,COG0179@2|Bacteria,1UY98@1239|Firmicutes,4HC89@91061|Bacilli,26UR6@186822|Paenibacillaceae 91061|Bacilli Q Fumarylacetoacetate (FAA) hydrolase family - - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase SYD1_k127_8455600_6 240015.ACP_3311 4.597e-158 508.0 COG3185@1|root,COG3185@2|Bacteria,3Y2ST@57723|Acidobacteria,2JISR@204432|Acidobacteriia 204432|Acidobacteriia E Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal - - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Glyoxalase SYD1_k127_8455600_21 404589.Anae109_1471 2.247e-29 127.0 COG0457@1|root,COG0457@2|Bacteria,1QX47@1224|Proteobacteria,42Y0X@68525|delta/epsilon subdivisions,2WT7V@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_2,Zincin_1 SYD1_k127_8455600_15 1379698.RBG1_1C00001G1293 4.89e-67 237.0 COG1845@1|root,COG1845@2|Bacteria,2NPIG@2323|unclassified Bacteria 2|Bacteria C cytochrome c oxidase subunit III ctaE GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - iJN678.ctaE COX3 SYD1_k127_8455600_0 1379698.RBG1_1C00001G1725 0.0 1458.0 COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria 2|Bacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family acrD - - ko:K03296,ko:K18138,ko:K18307 ko01501,ko01503,ko02024,map01501,map01503,map02024 M00644,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.20,2.A.6.2.32 - - ACR_tran SYD1_k127_8455600_11 1379698.RBG1_1C00001G1724 1.395e-101 372.0 COG0845@1|root,COG0845@2|Bacteria,2NR7K@2323|unclassified Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family mdtA - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 SYD1_k127_8455600_24 204669.Acid345_0373 8.833e-15 88.0 COG1538@1|root,COG1538@2|Bacteria,3Y3BF@57723|Acidobacteria,2JIVR@204432|Acidobacteriia 204432|Acidobacteriia MU outer membrane efflux protein - - - - - - - - - - - - OEP SYD1_k127_8455600_8 1487953.JMKF01000078_gene4088 1.028e-110 372.0 COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria,1H8JK@1150|Oscillatoriales 1117|Cyanobacteria O PDZ domain (Also known as DHR or GLGF) - - - ko:K08372 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Trypsin_2 SYD1_k127_8455600_19 391615.ABSJ01000052_gene1313 5.699e-46 178.0 COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,1RNQR@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Lysophospholipase ynbC GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 - - - - - - - - - - Hydrolase_4,Methyltransf_20 SYD1_k127_8455600_3 290397.Adeh_3457 1.209e-164 537.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,42M9Z@68525|delta/epsilon subdivisions,2WIYZ@28221|Deltaproteobacteria,2YU0Z@29|Myxococcales 28221|Deltaproteobacteria F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N SYD1_k127_8455600_13 1206735.BAGG01000021_gene1071 6.917e-79 282.0 COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4FW6U@85025|Nocardiaceae 201174|Actinobacteria C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C SYD1_k127_8455600_14 395961.Cyan7425_1650 1.569e-73 277.0 COG4221@1|root,COG4221@2|Bacteria,1G4EK@1117|Cyanobacteria,3KIA0@43988|Cyanothece 1117|Cyanobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short SYD1_k127_8455600_23 1123242.JH636434_gene3876 2.61e-22 107.0 COG0500@1|root,COG0500@2|Bacteria,2IYVY@203682|Planctomycetes 203682|Planctomycetes Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_25,Methyltransf_31 SYD1_k127_8455600_22 404589.Anae109_2532 1.732e-26 113.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2Z1SJ@29|Myxococcales 28221|Deltaproteobacteria K Cold shock protein - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD SYD1_k127_8455600_25 47763.JNZA01000015_gene867 8.774e-07 61.0 2E4H1@1|root,32ZC5@2|Bacteria,2IFIP@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - SYD1_k127_8455600_10 1267533.KB906738_gene2099 1.605e-108 374.0 COG1181@1|root,COG1181@2|Bacteria 2|Bacteria F Belongs to the D-alanine--D-alanine ligase family ddlA - 6.3.2.4,6.3.5.5 ko:K01921,ko:K01955 ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502 M00051 R00256,R00575,R01150,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N SYD1_k127_8455600_9 864051.BurJ1DRAFT_2702 7.846e-110 376.0 COG3266@1|root,COG3266@2|Bacteria,1R0CZ@1224|Proteobacteria 1224|Proteobacteria I PFAM Prenyltransferase squalene oxidase - - - - - - - - - - - - VCBS SYD1_k127_8455600_1 1382359.JIAL01000001_gene1745 3.382e-284 910.0 COG0612@1|root,COG0612@2|Bacteria,3Y2UB@57723|Acidobacteria,2JITC@204432|Acidobacteriia 204432|Acidobacteriia S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C SYD1_k127_8455600_20 379066.GAU_3352 7.635e-45 188.0 COG1528@1|root,COG1528@2|Bacteria,1ZUFX@142182|Gemmatimonadetes 142182|Gemmatimonadetes P Rubrerythrin - - 1.16.3.1 ko:K22336 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin SYD1_k127_8455600_4 314285.KT71_17271 2.216e-161 529.0 COG1404@1|root,COG1404@2|Bacteria,1PE2Y@1224|Proteobacteria,1SQ8B@1236|Gammaproteobacteria,1JBCF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Subtilase family - - - - - - - - - - - - Peptidase_S8 SYD1_k127_8455600_2 861299.J421_3607 1.165e-194 624.0 COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,1ZSQV@142182|Gemmatimonadetes 142182|Gemmatimonadetes G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase - - 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso,PIG-L SYD1_k127_8589475_2 580327.Tthe_0741 5.979e-116 387.0 COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,42J66@68295|Thermoanaerobacterales 186801|Clostridia T PFAM sigma-54 factor interaction domain-containing protein - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SYD1_k127_8589475_5 1340493.JNIF01000003_gene1293 4.9e-85 303.0 COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria 57723|Acidobacteria T Inner membrane component of T3SS, cytoplasmic domain - - - - - - - - - - - - FHA,GAF_3,SpoIIE SYD1_k127_8589475_10 1215092.PA6_013_00420 0.0003256 54.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1YE94@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840 - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri SYD1_k127_8589475_6 1238182.C882_1846 3.593e-47 180.0 2DQIT@1|root,33749@2|Bacteria,1N9CN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - VPEP SYD1_k127_8589475_0 1379698.RBG1_1C00001G0830 3.162e-215 689.0 COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria 2|Bacteria J elongation factor G fusA2 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 SYD1_k127_8589475_3 1379698.RBG1_1C00001G1263 3.069e-87 327.0 COG1404@1|root,COG1404@2|Bacteria,2NNSK@2323|unclassified Bacteria 2|Bacteria O Subtilase family aprN - - - - - - - - - - - Peptidase_S8 SYD1_k127_8589475_9 518766.Rmar_2727 1.806e-10 76.0 COG5563@1|root,COG5563@2|Bacteria 2|Bacteria - - CP_1072 - - - - - - - - - - - Autotransporter SYD1_k127_8589475_4 1499967.BAYZ01000068_gene1977 6.111e-87 293.0 COG0217@1|root,COG0217@2|Bacteria,2NNSI@2323|unclassified Bacteria 2|Bacteria K Transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg SYD1_k127_8589475_7 349163.Acry_2906 3.157e-37 148.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2U70Z@28211|Alphaproteobacteria,2JS5T@204441|Rhodospirillales 204441|Rhodospirillales L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC SYD1_k127_8589475_8 518766.Rmar_2313 3.331e-28 128.0 COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,1FJ9Q@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N SYD1_k127_8589475_1 1379698.RBG1_1C00001G0838 1.146e-128 423.0 COG2255@1|root,COG2255@2|Bacteria,2NNUG@2323|unclassified Bacteria 2|Bacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N SYD1_k127_8725008_163 1156844.KB891806_gene1808 8.634e-07 55.0 COG1028@1|root,COG1028@2|Bacteria,2GIVT@201174|Actinobacteria 201174|Actinobacteria IQ Short-chain dehydrogenase reductase sdr - - - - - - - - - - - - adh_short_C2 SYD1_k127_8725008_45 644966.Tmar_0464 1.213e-115 391.0 COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,249PW@186801|Clostridia,3WCSA@538999|Clostridiales incertae sedis 186801|Clostridia G Bacterial fructose-1,6-bisphosphatase, glpX-encoded glpX - 3.1.3.11 ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX SYD1_k127_8725008_89 518766.Rmar_0672 1.006e-55 205.0 COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1FIXS@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S GlcNAc-PI de-N-acetylase bshB1 - - ko:K01463 - - - - ko00000,ko01000 - - - PIG-L SYD1_k127_8725008_149 1123405.AUMM01000004_gene747 5.519e-15 89.0 COG3342@1|root,COG3342@2|Bacteria,1TS8U@1239|Firmicutes,4HBYK@91061|Bacilli,26NZT@186821|Sporolactobacillaceae 91061|Bacilli S Family of unknown function (DUF1028) - - - - - - - - - - - - DUF1028,PG_binding_2 SYD1_k127_8725008_39 1379698.RBG1_1C00001G0875 9.479e-126 425.0 COG3958@1|root,COG3958@2|Bacteria,2NQFH@2323|unclassified Bacteria 2|Bacteria G Transketolase, pyrimidine binding domain tktC - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C SYD1_k127_8725008_46 1379698.RBG1_1C00001G0874 2.595e-114 399.0 COG3959@1|root,COG3959@2|Bacteria,2NP12@2323|unclassified Bacteria 2|Bacteria G Transketolase, thiamine diphosphate binding domain - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N SYD1_k127_8725008_74 316274.Haur_4323 3.146e-75 275.0 COG0451@1|root,COG0451@2|Bacteria,2GBWQ@200795|Chloroflexi,3774S@32061|Chloroflexia 32061|Chloroflexia M PFAM NAD-dependent epimerase dehydratase - - - - - - - - - - - - Epimerase SYD1_k127_8725008_115 1123321.KB905814_gene2034 6.812e-36 151.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25 SYD1_k127_8725008_154 290397.Adeh_1533 1.611e-12 74.0 COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria,2YVR1@29|Myxococcales 28221|Deltaproteobacteria U Preprotein translocase SecG subunit secG - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG SYD1_k127_8725008_92 1038862.KB893806_gene3167 7.968e-53 206.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2TS6I@28211|Alphaproteobacteria,3JRGS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM SYD1_k127_8725008_42 945713.IALB_1271 1.417e-121 402.0 COG0126@1|root,COG0126@2|Bacteria 2|Bacteria F phosphoglycerate kinase activity pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK SYD1_k127_8725008_41 1242864.D187_005685 3.174e-123 420.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2WIK1@28221|Deltaproteobacteria,2YUMG@29|Myxococcales 28221|Deltaproteobacteria C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N SYD1_k127_8725008_32 1191523.MROS_2233 1.36e-140 454.0 COG0205@1|root,COG0205@2|Bacteria 2|Bacteria G 6-phosphofructokinase activity pfkA - 2.7.1.11,2.7.1.90 ko:K00850,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - - PFK SYD1_k127_8725008_145 1191523.MROS_0283 9.862e-18 98.0 COG4219@1|root,COG4219@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Amidase_6,DUF4309,DUF5301 SYD1_k127_8725008_91 880073.Calab_1556 3.522e-54 204.0 COG2067@1|root,COG2067@2|Bacteria,2NR34@2323|unclassified Bacteria 2|Bacteria I long-chain fatty acid transport protein - - - - - - - - - - - - - SYD1_k127_8725008_138 1379698.RBG1_1C00001G1819 1.706e-21 111.0 28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_8725008_71 880073.Calab_2215 1.088e-78 295.0 COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria 2|Bacteria P COGs COG1629 Outer membrane receptor protein mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec SYD1_k127_8725008_72 204669.Acid345_3766 1.655e-78 279.0 COG0312@1|root,COG0312@2|Bacteria,3Y7SM@57723|Acidobacteria 57723|Acidobacteria L Putative modulator of DNA gyrase - - - - - - - - - - - - PmbA_TldD SYD1_k127_8725008_20 204669.Acid345_3767 9.657e-161 520.0 COG0312@1|root,COG0312@2|Bacteria,3Y6TF@57723|Acidobacteria 57723|Acidobacteria L Putative modulator of DNA gyrase - - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD SYD1_k127_8725008_22 290397.Adeh_1076 2.793e-158 519.0 COG1543@1|root,COG1543@2|Bacteria,1R5SN@1224|Proteobacteria,42PSX@68525|delta/epsilon subdivisions,2WU5G@28221|Deltaproteobacteria,2YTTH@29|Myxococcales 28221|Deltaproteobacteria G Belongs to the glycosyl hydrolase 57 family - - 2.4.1.18 ko:K16149 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000 - GH57 - DUF1957,Glyco_hydro_57 SYD1_k127_8725008_168 498761.HM1_2045 5.475e-05 54.0 COG3330@1|root,COG3330@2|Bacteria,1TY60@1239|Firmicutes,2578K@186801|Clostridia 186801|Clostridia S Domain of unknown function (DUF4912) - - - ko:K09942 - - - - ko00000 - - - DUF4912 SYD1_k127_8725008_127 314230.DSM3645_23935 2.6e-27 129.0 2EYTK@1|root,33S0U@2|Bacteria,2IYA9@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - Dockerin_1 SYD1_k127_8725008_144 1282360.ABAC460_13310 9.107e-18 99.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2U5KI@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - Cadherin,HemolysinCabind SYD1_k127_8725008_33 439235.Dalk_2389 2.881e-140 474.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2WITH@28221|Deltaproteobacteria,2MHR7@213118|Desulfobacterales 28221|Deltaproteobacteria G phosphoglucomutase phosphomannomutase alpha beta alpha domain I algC - 5.4.2.2,5.4.2.8 ko:K01840,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV SYD1_k127_8725008_44 880073.Calab_1379 1.52e-117 388.0 COG1186@1|root,COG1186@2|Bacteria,2NNU3@2323|unclassified Bacteria 2|Bacteria J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 SYD1_k127_8725008_128 1089553.Tph_c18060 7.143e-27 117.0 COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,42G1K@68295|Thermoanaerobacterales 186801|Clostridia F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE - 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE SYD1_k127_8725008_3 1379698.RBG1_1C00001G0871 7.203e-228 740.0 COG0749@1|root,COG0749@2|Bacteria,2NNKA@2323|unclassified Bacteria 2|Bacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 SYD1_k127_8725008_112 309801.trd_0651 1.317e-38 162.0 COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi,27Y96@189775|Thermomicrobia 189775|Thermomicrobia F Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like SYD1_k127_8725008_118 1379698.RBG1_1C00001G0869 3.293e-34 149.0 COG4105@1|root,COG4105@2|Bacteria,2NPZ3@2323|unclassified Bacteria 2|Bacteria S Outer membrane lipoprotein yfiO - - ko:K05807,ko:K08309 - - - - ko00000,ko01000,ko01011,ko02000 1.B.33.1 GH23 - YfiO SYD1_k127_8725008_108 1125863.JAFN01000001_gene1608 1.147e-41 163.0 COG0457@1|root,COG0457@2|Bacteria,1N5BD@1224|Proteobacteria,42U63@68525|delta/epsilon subdivisions,2WQUR@28221|Deltaproteobacteria 28221|Deltaproteobacteria S TPR repeat - - - - - - - - - - - - TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8 SYD1_k127_8725008_51 498761.HM1_2369 2.441e-109 394.0 COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia 186801|Clostridia J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 SYD1_k127_8725008_23 1125863.JAFN01000001_gene3585 9.938e-153 510.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria 28221|Deltaproteobacteria D PFAM cell divisionFtsK SpoIIIE ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma SYD1_k127_8725008_13 926569.ANT_16170 1.101e-187 594.0 COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi 200795|Chloroflexi H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD SYD1_k127_8725008_19 671143.DAMO_0276 3.933e-161 516.0 COG0192@1|root,COG0192@2|Bacteria,2NNYF@2323|unclassified Bacteria 2|Bacteria H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N SYD1_k127_8725008_66 1519464.HY22_02585 1.094e-82 300.0 COG1209@1|root,COG1209@2|Bacteria,1FD8Z@1090|Chlorobi 1090|Chlorobi M Nucleotidyl transferase - - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase SYD1_k127_8725008_93 1121430.JMLG01000009_gene429 3.641e-52 211.0 COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,25ZZA@186807|Peptococcaceae 186801|Clostridia G Sugar isomerase (SIS) - - 5.3.1.8,5.3.1.9 ko:K15916 ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R01819,R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000 - - - SIS,bact-PGI_C SYD1_k127_8725008_28 273068.TTE2334 4.52e-145 488.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales 186801|Clostridia G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsP - 2.7.3.9,2.7.9.2 ko:K01007,ko:K08483 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C SYD1_k127_8725008_142 443144.GM21_3385 5.069e-19 99.0 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,42V5C@68525|delta/epsilon subdivisions,2WRC4@28221|Deltaproteobacteria 28221|Deltaproteobacteria G TIGRFAM phosphocarrier, HPr family ptsH - - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr SYD1_k127_8725008_136 1045854.WKK_01825 4.189e-22 111.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,4AWH1@81850|Leuconostocaceae 91061|Bacilli G Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID manN - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA SYD1_k127_8725008_132 1379698.RBG1_1C00001G0555 1.489e-25 115.0 COG3444@1|root,COG3444@2|Bacteria,2NQ0P@2323|unclassified Bacteria 2|Bacteria G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794,ko:K19507 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276,M00764 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1,4.A.6.1.19 - - PTSIIB_sorb SYD1_k127_8725008_146 1379698.RBG1_1C00001G0554 7.214e-16 83.0 COG2893@1|root,COG2893@2|Bacteria,2NRZU@2323|unclassified Bacteria 2|Bacteria G system, fructose subfamily IIA component - - 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man SYD1_k127_8725008_55 1379698.RBG1_1C00001G0553 1.6e-101 345.0 COG1493@1|root,COG1493@2|Bacteria,2NP5B@2323|unclassified Bacteria 2|Bacteria T Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N SYD1_k127_8725008_161 643648.Slip_1879 1.128e-07 61.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,42JZ4@68298|Syntrophomonadaceae 186801|Clostridia J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE SYD1_k127_8725008_50 1379698.RBG1_1C00001G0551 5.493e-110 374.0 COG1508@1|root,COG1508@2|Bacteria,2NNZA@2323|unclassified Bacteria 2|Bacteria K RNA polymerase sigma-54 factor rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD SYD1_k127_8725008_60 373903.Hore_17500 2.437e-94 314.0 COG1137@1|root,COG1137@2|Bacteria,1UJSV@1239|Firmicutes,25F98@186801|Clostridia,3WAB6@53433|Halanaerobiales 186801|Clostridia S PFAM ABC transporter - - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran SYD1_k127_8725008_131 1379698.RBG1_1C00001G0548 9.33e-26 115.0 COG3117@1|root,COG3117@2|Bacteria,2NQ8Q@2323|unclassified Bacteria 2|Bacteria S Lipopolysaccharide-assembly, LptC-related lptC - - ko:K09774,ko:K11719 - - - - ko00000,ko02000 1.B.42.1 - - LptC SYD1_k127_8725008_62 1166948.JPZL01000001_gene2453 1.24e-89 315.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1XI8M@135619|Oceanospirillales 135619|Oceanospirillales M Arabinose 5-phosphate isomerase kpsF - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS SYD1_k127_8725008_67 1123368.AUIS01000001_gene2059 6.076e-82 284.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,2NCMH@225057|Acidithiobacillales 225057|Acidithiobacillales M 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 SYD1_k127_8725008_6 429009.Adeg_0051 1.501e-216 696.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,42F21@68295|Thermoanaerobacterales 186801|Clostridia F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS01075 CTP_synth_N,GATase SYD1_k127_8725008_84 1410613.JNKF01000011_gene893 4.207e-59 214.0 COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,2FMHD@200643|Bacteroidia 976|Bacteroidetes M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 SYD1_k127_8725008_48 370438.PTH_1367 3.735e-113 376.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,260EM@186807|Peptococcaceae 186801|Clostridia C Catalyzes the reversible oxidation of malate to oxaloacetate mdh - 1.1.1.27,1.1.1.37 ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R00703,R01000,R03104,R07136 RC00031,RC00044 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N SYD1_k127_8725008_124 1487953.JMKF01000009_gene6172 3.507e-30 121.0 COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria,1HCCX@1150|Oscillatoriales 1117|Cyanobacteria J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 SYD1_k127_8725008_143 1008457.BAEX01000107_gene2166 8.435e-18 87.0 COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,1HYAI@117743|Flavobacteriia,47I7H@76831|Myroides 976|Bacteroidetes J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - HHH_5,Rho_N,Ribosomal_L21p SYD1_k127_8725008_21 1379270.AUXF01000006_gene192 3.68e-160 519.0 COG1530@1|root,COG1530@2|Bacteria,1ZSZS@142182|Gemmatimonadetes 142182|Gemmatimonadetes J Ribonuclease E/G family - - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G SYD1_k127_8725008_12 880073.Calab_2282 7.967e-189 626.0 COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,2NNKI@2323|unclassified Bacteria 2|Bacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - DUF2344,Radical_SAM SYD1_k127_8725008_130 1307759.JOMJ01000003_gene1100 7.4e-26 117.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,2MGES@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM Phosphoribosyltransferase - - - - - - - - - - - - Pribosyltran SYD1_k127_8725008_103 290397.Adeh_0185 3.824e-43 170.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,42N54@68525|delta/epsilon subdivisions,2WNYG@28221|Deltaproteobacteria,2Z1BJ@29|Myxococcales 28221|Deltaproteobacteria E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N SYD1_k127_8725008_96 1379698.RBG1_1C00001G1006 4.793e-50 190.0 COG0682@1|root,COG0682@2|Bacteria,2NPK2@2323|unclassified Bacteria 2|Bacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT SYD1_k127_8725008_58 1379698.RBG1_1C00001G1004 3.687e-97 336.0 COG0772@1|root,COG0772@2|Bacteria,2NNRP@2323|unclassified Bacteria 2|Bacteria D Peptidoglycan polymerase that is essential for cell wall elongation rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE SYD1_k127_8725008_27 1379698.RBG1_1C00001G1003 3.474e-145 481.0 COG0768@1|root,COG0768@2|Bacteria,2NNYI@2323|unclassified Bacteria 2|Bacteria M Penicillin-binding protein 2 mrdA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604 PBP_dimer,Transpeptidase SYD1_k127_8725008_152 1499967.BAYZ01000147_gene720 5.539e-14 85.0 COG2891@1|root,COG2891@2|Bacteria,2NRRJ@2323|unclassified Bacteria 2|Bacteria M rod shape-determining protein MreD mreD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD SYD1_k127_8725008_119 643648.Slip_0689 1.906e-33 143.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,42K0F@68298|Syntrophomonadaceae 186801|Clostridia M Involved in formation and maintenance of cell shape mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC SYD1_k127_8725008_26 1379698.RBG1_1C00001G1860 4.529e-146 471.0 COG1077@1|root,COG1077@2|Bacteria,2NNVU@2323|unclassified Bacteria 2|Bacteria D MreB/Mbl protein mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl SYD1_k127_8725008_140 1384054.N790_14595 1.893e-20 104.0 COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,1S510@1236|Gammaproteobacteria,1X48B@135614|Xanthomonadales 135614|Xanthomonadales S membrane protein (homolog of Drosophila rhomboid) - - - - - - - - - - - - Rhomboid SYD1_k127_8725008_16 1379698.RBG1_1C00001G1029 6.664e-179 573.0 COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria 2|Bacteria E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA - 1.4.1.3,1.4.1.4 ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N SYD1_k127_8725008_86 292459.STH2808 2.69e-56 208.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,24ABA@186801|Clostridia 186801|Clostridia V LD-carboxypeptidase - - 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S66 SYD1_k127_8725008_102 1382359.JIAL01000001_gene1393 9.183e-45 186.0 COG2027@1|root,COG2027@2|Bacteria,3Y3WF@57723|Acidobacteria,2JIBN@204432|Acidobacteriia 204432|Acidobacteriia M PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C - - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 SYD1_k127_8725008_79 945713.IALB_1171 2.415e-64 236.0 COG2067@1|root,COG2067@2|Bacteria 2|Bacteria I long-chain fatty acid transporting porin activity - - - - - - - - - - - - PorP_SprF SYD1_k127_8725008_49 1191523.MROS_0285 5.7e-111 394.0 2E09V@1|root,32VXB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SYD1_k127_8725008_43 945713.IALB_0757 6.268e-120 422.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec SYD1_k127_8725008_111 1379698.RBG1_1C00001G1368 6.89e-39 163.0 COG4219@1|root,COG4219@2|Bacteria,2NS3V@2323|unclassified Bacteria 2|Bacteria KT Peptidase M56 - - - - - - - - - - - - Amidase_6,DUF4309,DUF5301 SYD1_k127_8725008_159 518766.Rmar_2820 1.071e-08 69.0 COG2374@1|root,COG2374@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Endonuclease_1,Exo_endo_phos,LTD SYD1_k127_8725008_158 316274.Haur_0788 8.918e-10 72.0 COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi 200795|Chloroflexi S LVIVD repeat - - - - - - - - - - - - LVIVD SYD1_k127_8725008_83 1234364.AMSF01000087_gene2795 3.505e-59 211.0 COG0586@1|root,COG0586@2|Bacteria,1RGII@1224|Proteobacteria,1S844@1236|Gammaproteobacteria,1XCVR@135614|Xanthomonadales 135614|Xanthomonadales S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc SYD1_k127_8725008_25 1396141.BATP01000003_gene5047 4.734e-150 509.0 COG0612@1|root,COG0612@2|Bacteria,46S9I@74201|Verrucomicrobia,2ITJG@203494|Verrucomicrobiae 74201|Verrucomicrobia S Insulinase (Peptidase family M16) - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C SYD1_k127_8725008_54 247490.KSU1_B0195 5.828e-102 366.0 COG0438@1|root,COG0438@2|Bacteria,2IXRB@203682|Planctomycetes 203682|Planctomycetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SYD1_k127_8725008_24 1209989.TepiRe1_1817 2.95e-150 490.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales 186801|Clostridia J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c SYD1_k127_8725008_151 880073.Calab_0913 4.953e-14 87.0 COG1523@1|root,COG1523@2|Bacteria 2|Bacteria G belongs to the glycosyl hydrolase 13 family - - - - - - - - - - - - Alpha-amylase,CBM_48 SYD1_k127_8725008_107 443143.GM18_4316 6.829e-42 179.0 COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria 28221|Deltaproteobacteria O Belongs to the peptidase S8 family - - 3.4.21.66 ko:K08651 - - - - ko00000,ko01000,ko01002,ko03110 - - - Big_2,CUB,He_PIG,Peptidase_S8 SYD1_k127_8725008_133 439235.Dalk_2302 1.675e-25 125.0 COG4870@1|root,COG4870@2|Bacteria,1NC9B@1224|Proteobacteria 1224|Proteobacteria O PFAM Peptidase C1A, papain - - - - - - - - - - - - Peptidase_C1 SYD1_k127_8725008_5 243231.GSU3423 4.809e-219 699.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,43UFT@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N SYD1_k127_8725008_56 1122176.KB903550_gene4308 2.403e-101 351.0 COG4784@1|root,COG4784@2|Bacteria,4PM59@976|Bacteroidetes,1J075@117747|Sphingobacteriia 976|Bacteroidetes S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 SYD1_k127_8725008_155 1121378.KB899762_gene3377 1.048e-11 75.0 COG0398@1|root,COG0398@2|Bacteria 2|Bacteria M Pfam SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc SYD1_k127_8725008_1 326427.Cagg_3721 0.0 1251.0 COG1048@1|root,COG1048@2|Bacteria,2G5NG@200795|Chloroflexi,374T1@32061|Chloroflexia 32061|Chloroflexia C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C SYD1_k127_8725008_37 479434.Sthe_2282 1.154e-136 486.0 COG2217@1|root,COG2217@2|Bacteria,2G5QF@200795|Chloroflexi,27YTH@189775|Thermomicrobia 189775|Thermomicrobia P E1-E2 ATPase - - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase SYD1_k127_8725008_47 290397.Adeh_0511 1.086e-113 379.0 COG0475@1|root,COG0475@2|Bacteria,1RA3J@1224|Proteobacteria,43EWJ@68525|delta/epsilon subdivisions,2WTW1@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger SYD1_k127_8725008_123 525904.Tter_2020 3.289e-30 129.0 COG0664@1|root,COG0664@2|Bacteria,2NPVK@2323|unclassified Bacteria 2|Bacteria K Transcriptional regulator, Crp Fnr family nnrR - - ko:K01420,ko:K21564 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding SYD1_k127_8725008_165 1894.JOER01000025_gene6931 1.261e-05 54.0 COG5592@1|root,COG5592@2|Bacteria 2|Bacteria I hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin SYD1_k127_8725008_139 1124780.ANNU01000013_gene3870 1.928e-21 106.0 COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,47R42@768503|Cytophagia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C SYD1_k127_8725008_4 452637.Oter_1803 1.251e-222 707.0 COG4263@1|root,COG4263@2|Bacteria,46YT5@74201|Verrucomicrobia,3K7SZ@414999|Opitutae 414999|Opitutae C Cupredoxin-like domain - - 1.7.2.4 ko:K00376 ko00910,ko01120,map00910,map01120 M00529 R02804 RC02861 ko00000,ko00001,ko00002,ko01000 - - - Cupredoxin_1 SYD1_k127_8725008_122 404589.Anae109_0245 3.125e-30 139.0 COG4314@1|root,COG4314@2|Bacteria,1R8N3@1224|Proteobacteria,42M7R@68525|delta/epsilon subdivisions,2WXID@28221|Deltaproteobacteria 28221|Deltaproteobacteria C lipoprotein involved in nitrous oxide reduction - - - - - - - - - - - - - SYD1_k127_8725008_85 1124780.ANNU01000013_gene3867 9.543e-59 223.0 COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,47KEF@768503|Cytophagia 976|Bacteroidetes P Periplasmic copper-binding protein (NosD) nosD - - ko:K07218 - - - - ko00000 - - - NosD SYD1_k127_8725008_98 867903.ThesuDRAFT_00747 3.03e-49 200.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,3WD2R@538999|Clostridiales incertae sedis 186801|Clostridia V ABC transporter yfiL - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 SYD1_k127_8725008_137 318161.Sden_2216 7.22e-22 112.0 COG1277@1|root,COG1277@2|Bacteria,1MWUZ@1224|Proteobacteria,1RQFG@1236|Gammaproteobacteria,2QB2S@267890|Shewanellaceae 1236|Gammaproteobacteria S ABC-2 family transporter protein nosY - - ko:K19341 ko02010,map02010 M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 - - ABC2_membrane_2 SYD1_k127_8725008_129 404589.Anae109_4276 1.62e-26 124.0 COG3213@1|root,COG3213@2|Bacteria,1Q61U@1224|Proteobacteria,4328M@68525|delta/epsilon subdivisions,2WXFV@28221|Deltaproteobacteria 28221|Deltaproteobacteria P NnrS protein - - - ko:K07234 - - - - ko00000 - - - NnrS SYD1_k127_8725008_141 1124780.ANNU01000013_gene3870 4.091e-19 94.0 COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,47R42@768503|Cytophagia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C SYD1_k127_8725008_65 1379270.AUXF01000007_gene1057 1.131e-83 292.0 COG3174@1|root,COG3174@2|Bacteria,1ZUTX@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Domain of unknown function (DUF4010) - - - - - - - - - - - - DUF4010,MgtC SYD1_k127_8725008_172 1122223.KB890687_gene2514 0.000229 51.0 COG1434@1|root,COG1434@2|Bacteria,1WMS4@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S DUF218 domain - - - - - - - - - - - - DUF218 SYD1_k127_8725008_116 234267.Acid_2706 2.843e-35 143.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase menG - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran SYD1_k127_8725008_114 1379698.RBG1_1C00001G1091 5.142e-36 161.0 COG0823@1|root,COG2911@1|root,COG0823@2|Bacteria,COG2911@2|Bacteria,2NS5I@2323|unclassified Bacteria 2|Bacteria U FlgD Ig-like domain - - - ko:K13669 - - - - ko00000,ko01000,ko01003 - GT87 - CBM_6,Cellulase,FlgD_ig,GT87,PD40,VCBS SYD1_k127_8725008_31 118168.MC7420_6518 8.792e-141 507.0 COG0823@1|root,COG1404@1|root,COG2931@1|root,COG0823@2|Bacteria,COG1404@2|Bacteria,COG2931@2|Bacteria,1G04D@1117|Cyanobacteria,1H779@1150|Oscillatoriales 1117|Cyanobacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - Calx-beta,HemolysinCabind,Peptidase_S8,SdrD_B SYD1_k127_8725008_169 1265502.KB905931_gene1744 0.0001129 55.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria,4A9PX@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM Patatin - - - ko:K07001 - - - - ko00000 - - - Patatin SYD1_k127_8725008_166 1449353.JQMQ01000005_gene413 2.808e-05 57.0 COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,2NG8W@228398|Streptacidiphilus 201174|Actinobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin SYD1_k127_8725008_75 1254432.SCE1572_06490 1.073e-71 254.0 COG0122@1|root,COG0350@1|root,COG0122@2|Bacteria,COG0350@2|Bacteria,1MVF7@1224|Proteobacteria,43ARM@68525|delta/epsilon subdivisions,2X65K@28221|Deltaproteobacteria,2Z392@29|Myxococcales 28221|Deltaproteobacteria L 6-O-methylguanine DNA methyltransferase, DNA binding domain - - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,HhH-GPD SYD1_k127_8725008_117 983920.Y88_2463 6.959e-35 156.0 COG0526@1|root,COG0526@2|Bacteria,1QTY9@1224|Proteobacteria,2TW6Y@28211|Alphaproteobacteria,2K3FX@204457|Sphingomonadales 204457|Sphingomonadales CO AhpC/TSA family - - - - - - - - - - - - AhpC-TSA,Redoxin SYD1_k127_8725008_0 765420.OSCT_2846 0.0 1352.0 COG0458@1|root,COG0458@2|Bacteria,2G5NX@200795|Chloroflexi,375DP@32061|Chloroflexia 32061|Chloroflexia F Carbamoyl-phosphate synthetase large chain domain protein carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS SYD1_k127_8725008_38 338963.Pcar_1613 1.376e-134 439.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,43SCX@69541|Desulfuromonadales 28221|Deltaproteobacteria F Carbamoyl-phosphate synthase small chain, CPSase domain carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase SYD1_k127_8725008_105 639282.DEFDS_1443 2.087e-42 161.0 COG2905@1|root,COG2905@2|Bacteria,2GGGX@200930|Deferribacteres 200930|Deferribacteres T Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS SYD1_k127_8725008_88 1267535.KB906767_gene4272 8.101e-56 205.0 COG0229@1|root,COG0229@2|Bacteria,3Y4XW@57723|Acidobacteria,2JMYE@204432|Acidobacteriia 204432|Acidobacteriia C SelR domain - - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR SYD1_k127_8725008_8 1255043.TVNIR_1860 2.066e-208 659.0 COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1WW29@135613|Chromatiales 135613|Chromatiales S PFAM Uncharacterised protein family UPF0027 rtcB - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB SYD1_k127_8725008_106 1123354.AUDR01000015_gene351 4.401e-42 173.0 COG1371@1|root,COG1371@2|Bacteria 2|Bacteria J PFAM Archease protein family (DUF101 UPF0211) - - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Archease SYD1_k127_8725008_80 1123368.AUIS01000038_gene38 1.121e-62 235.0 COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,1S3SH@1236|Gammaproteobacteria,2NCU9@225057|Acidithiobacillales 225057|Acidithiobacillales S Phosphoribosyl transferase domain - - - - - - - - - - - - Pribosyltran SYD1_k127_8725008_153 883.DvMF_0804 4.709e-13 81.0 COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WR88@28221|Deltaproteobacteria,2MDMW@213115|Desulfovibrionales 28221|Deltaproteobacteria T Universal stress protein - - - - - - - - - - - - Usp SYD1_k127_8725008_30 1163617.SCD_n02012 2.887e-143 468.0 COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria 28216|Betaproteobacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 SYD1_k127_8725008_157 522306.CAP2UW1_1169 1.88e-10 72.0 COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,2VRQB@28216|Betaproteobacteria 28216|Betaproteobacteria J ribosomal large subunit export from nucleus - - - - - - - - - - - - - SYD1_k127_8725008_40 1379698.RBG1_1C00001G0364 6.163e-125 408.0 COG0306@1|root,COG0306@2|Bacteria,2NP4R@2323|unclassified Bacteria 2|Bacteria P Phosphate transporter family pit - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 SYD1_k127_8725008_97 269799.Gmet_3132 6.824e-50 193.0 COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,42SPV@68525|delta/epsilon subdivisions,2WPTH@28221|Deltaproteobacteria,43SW8@69541|Desulfuromonadales 28221|Deltaproteobacteria P Protein of unknown function DUF47 - - - ko:K07220 - - - - ko00000 - - - PhoU_div SYD1_k127_8725008_76 1144275.COCOR_02098 1.203e-68 250.0 COG0392@1|root,COG0392@2|Bacteria,1R468@1224|Proteobacteria 1224|Proteobacteria S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM SYD1_k127_8725008_94 1379698.RBG1_1C00001G0244 5.265e-51 190.0 COG1764@1|root,COG1764@2|Bacteria,2NQ0N@2323|unclassified Bacteria 2|Bacteria O OsmC-like protein osmC GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 - ko:K04063 - - - - ko00000 - - - OsmC SYD1_k127_8725008_10 215803.DB30_3780 2.218e-193 626.0 COG0339@1|root,COG0339@2|Bacteria,1R4AJ@1224|Proteobacteria,43BI1@68525|delta/epsilon subdivisions,2WMHM@28221|Deltaproteobacteria,2YUF2@29|Myxococcales 28221|Deltaproteobacteria E Peptidase family M3 - - 3.4.24.15 ko:K01392 ko04614,ko05143,map04614,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M3 SYD1_k127_8725008_64 1192034.CAP_0277 1.783e-85 290.0 COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,42SUD@68525|delta/epsilon subdivisions,2WP5H@28221|Deltaproteobacteria,2Z2DD@29|Myxococcales 28221|Deltaproteobacteria G Phosphoglycerate mutase family - - 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 SYD1_k127_8725008_156 1123508.JH636440_gene2588 1.026e-10 73.0 COG3391@1|root,COG3391@2|Bacteria,2IYYA@203682|Planctomycetes 203682|Planctomycetes S NHL repeat - - - - - - - - - - - - NHL SYD1_k127_8725008_174 913865.DOT_3430 0.0006129 51.0 2DT53@1|root,32UUF@2|Bacteria,1VDKB@1239|Firmicutes,24NQ3@186801|Clostridia,2642V@186807|Peptococcaceae 186801|Clostridia P Doubled CXXCH motif (Paired_CXXCH_1) - - - - - - - - - - - - Paired_CXXCH_1 SYD1_k127_8725008_113 880073.Calab_1263 3.964e-38 161.0 COG3303@1|root,COG3303@2|Bacteria 2|Bacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - - - - - - - - - - Paired_CXXCH_1 SYD1_k127_8725008_147 404589.Anae109_1833 1.038e-15 89.0 COG4380@1|root,COG4380@2|Bacteria,1NJYS@1224|Proteobacteria,42X1E@68525|delta/epsilon subdivisions,2WTEE@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Putative bacterial lipoprotein (DUF799) - - - - - - - - - - - - DUF799 SYD1_k127_8725008_160 589865.DaAHT2_0401 6.881e-08 64.0 COG3417@1|root,COG3417@2|Bacteria,1NVM9@1224|Proteobacteria,4307F@68525|delta/epsilon subdivisions,2WV4Y@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Peptidoglycan-synthase activator LpoB - - - - - - - - - - - - LpoB SYD1_k127_8725008_173 1162668.LFE_2144 0.0003971 52.0 COG1333@1|root,COG1333@2|Bacteria,3J0N7@40117|Nitrospirae 40117|Nitrospirae O ResB-like family - - - ko:K07399 - - - - ko00000 - - - ResB SYD1_k127_8725008_9 1121920.AUAU01000024_gene2388 1.653e-197 662.0 COG3005@1|root,COG3043@1|root,COG3005@2|Bacteria,COG3043@2|Bacteria,3Y4BJ@57723|Acidobacteria 57723|Acidobacteria C Doubled CXXCH motif (Paired_CXXCH_1) - - - - - - - - - - - - Paired_CXXCH_1 SYD1_k127_8725008_148 323848.Nmul_A2462 4.926e-15 86.0 COG0705@1|root,COG0705@2|Bacteria,1PRTS@1224|Proteobacteria,2VM82@28216|Betaproteobacteria,372KP@32003|Nitrosomonadales 28216|Betaproteobacteria S Rhomboid family - - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Lactonase,Rhomboid SYD1_k127_8725008_70 1123508.JH636439_gene1351 3.383e-79 277.0 COG1253@1|root,COG1253@2|Bacteria,2IYEG@203682|Planctomycetes 203682|Planctomycetes S CBS domain - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 SYD1_k127_8725008_18 247490.KSU1_C0443 1.417e-161 529.0 COG0526@1|root,COG3391@1|root,COG0526@2|Bacteria,COG3391@2|Bacteria,2IXWV@203682|Planctomycetes 203682|Planctomycetes CO PFAM NHL repeat - - - - - - - - - - - - NHL,Thioredoxin_8 SYD1_k127_8725008_57 1254432.SCE1572_28920 1.289e-100 336.0 COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,42N2Q@68525|delta/epsilon subdivisions,2X9TY@28221|Deltaproteobacteria,2YV7W@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribA - 3.5.4.25 ko:K01497 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125 R00425 RC00293,RC02504 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydro2 SYD1_k127_8725008_11 215803.DB30_2893 2.648e-190 631.0 COG0339@1|root,COG0339@2|Bacteria,1R4AJ@1224|Proteobacteria,43BI1@68525|delta/epsilon subdivisions,2WMHM@28221|Deltaproteobacteria,2YYTH@29|Myxococcales 28221|Deltaproteobacteria E Peptidase family M3 prlC1 - 3.4.24.15 ko:K01392 ko04614,ko05143,map04614,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M3 SYD1_k127_8725008_170 1172179.AUKV01000009_gene4532 0.0001378 53.0 COG2846@1|root,COG2846@2|Bacteria,2HC8E@201174|Actinobacteria 201174|Actinobacteria D Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin SYD1_k127_8725008_104 380749.HY04AAS1_0369 8.119e-43 162.0 COG0698@1|root,COG0698@2|Bacteria,2G43P@200783|Aquificae 200783|Aquificae G ribose 5-phosphate isomerase B rpiB - 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - LacAB_rpiB SYD1_k127_8725008_36 479434.Sthe_2434 4.219e-138 460.0 COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,2G67J@200795|Chloroflexi,27XXA@189775|Thermomicrobia 189775|Thermomicrobia G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2,5.3.1.9 ko:K13810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00004,M00007,M00114 R01827,R02739,R02740,R03321 RC00376,RC00439,RC00563,RC00604 ko00000,ko00001,ko00002,ko01000 - - - PGI,TAL_FSA SYD1_k127_8725008_125 1379698.RBG1_1C00001G0405 2.168e-29 127.0 COG4784@1|root,COG4784@2|Bacteria,2NS4E@2323|unclassified Bacteria 2|Bacteria S Peptidase family M48 MA20_40030 - - - - - - - - - - - LysM,Peptidase_M48 SYD1_k127_8725008_162 1151122.AQYD01000007_gene1021 4.09e-07 62.0 COG2764@1|root,COG2764@2|Bacteria,2I7IT@201174|Actinobacteria,4FSQ6@85023|Microbacteriaceae 201174|Actinobacteria S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase SYD1_k127_8725008_59 1038859.AXAU01000002_gene595 5.945e-95 324.0 COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,3JR2T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2,5.3.1.9 ko:K01810,ko:K13810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00004,M00007,M00114 R01827,R02739,R02740,R03321 RC00376,RC00439,RC00563,RC00604 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI,TAL_FSA SYD1_k127_8725008_52 309801.trd_1142 3.743e-108 384.0 COG1023@1|root,COG1023@2|Bacteria,2G5YD@200795|Chloroflexi,27XH5@189775|Thermomicrobia 189775|Thermomicrobia C 6-phosphogluconate dehydrogenase, C-terminal domain - - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 SYD1_k127_8725008_14 383372.Rcas_1852 3.002e-186 610.0 COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,374UD@32061|Chloroflexia 32061|Chloroflexia G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N SYD1_k127_8725008_134 768671.ThimaDRAFT_4167 1.489e-24 121.0 COG3429@1|root,COG3429@2|Bacteria,1RBF5@1224|Proteobacteria,1S24Z@1236|Gammaproteobacteria,1X00I@135613|Chromatiales 135613|Chromatiales G Glucose-6-phosphate dehydrogenase subunit - - - - - - - - - - - - OpcA_G6PD_assem SYD1_k127_8725008_77 443144.GM21_2219 2.357e-67 254.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,42QTP@68525|delta/epsilon subdivisions,2WN6N@28221|Deltaproteobacteria 28221|Deltaproteobacteria G Belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase SYD1_k127_8725008_29 485913.Krac_7522 5.264e-145 483.0 COG1830@1|root,COG1830@2|Bacteria,2G8VI@200795|Chloroflexi 200795|Chloroflexi G DeoC/LacD family aldolase - - 4.1.2.13 ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - DeoC SYD1_k127_8725008_126 1379698.RBG1_1C00001G1295 9.969e-29 124.0 COG3175@1|root,COG3175@2|Bacteria 2|Bacteria O copper ion binding ctaG GO:0008150,GO:0008535,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - ko:K02258 ko00190,ko01100,ko04714,map00190,map01100,map04714 M00154 - - ko00000,ko00001,ko00002,ko03029 3.D.4.8 - - CtaG_Cox11 SYD1_k127_8725008_63 1379698.RBG1_1C00001G1296 5.394e-86 293.0 COG0109@1|root,COG0109@2|Bacteria,2NPBW@2323|unclassified Bacteria 2|Bacteria O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA SYD1_k127_8725008_121 1100721.ALKO01000021_gene785 1.847e-31 135.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2VJ3C@28216|Betaproteobacteria,4AB9J@80864|Comamonadaceae 28216|Betaproteobacteria O cytochrome oxidase assembly ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA SYD1_k127_8725008_7 1379698.RBG1_1C00001G1298 2.198e-210 667.0 COG0843@1|root,COG0843@2|Bacteria,2NNTQ@2323|unclassified Bacteria 2|Bacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B cyoB GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009486,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015453,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0020037,GO:0022804,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0040007,GO:0042773,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902494,GO:1902600 1.10.3.10,1.10.3.12,1.9.3.1 ko:K02274,ko:K02298,ko:K02827,ko:K15408 ko00190,ko01100,map00190,map01100 M00155,M00416,M00417 R00081,R09492,R11335 RC00016,RC00061,RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1,3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6 - - COX1 SYD1_k127_8725008_69 1379698.RBG1_1C00001G1299 4.786e-80 276.0 COG1622@1|root,COG1622@2|Bacteria,2NNSH@2323|unclassified Bacteria 2|Bacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) ctaC GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 SYD1_k127_8725008_110 1379698.RBG1_1C00001G1300 9.896e-40 170.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c pbrT - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - Cytochrom_C,Cytochrome_CBB3,FTR1 SYD1_k127_8725008_61 1379698.RBG1_1C00001G1301 2.566e-93 324.0 COG4531@1|root,COG4531@2|Bacteria,2NP5Y@2323|unclassified Bacteria 2|Bacteria P ABC-type Zn2 transport system, periplasmic component surface adhesin actF - - - - - - - - - - - - SYD1_k127_8725008_95 1379698.RBG1_1C00001G1302 1.655e-50 186.0 COG2010@1|root,COG2010@2|Bacteria,2NPQJ@2323|unclassified Bacteria 2|Bacteria C Cytochrome C oxidase, cbb3-type, subunit III actE - - - - - - - - - - - Cytochrome_CBB3 SYD1_k127_8725008_100 1379698.RBG1_1C00001G1303 3.621e-48 179.0 COG2010@1|root,COG2010@2|Bacteria,2NPSE@2323|unclassified Bacteria 2|Bacteria C Protein of unknown function (DUF3341) actD - - - - - - - - - - - DUF3341 SYD1_k127_8725008_15 1379698.RBG1_1C00001G1304 9.906e-185 623.0 COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria 2|Bacteria C Polysulphide reductase, NrfD actC - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD SYD1_k127_8725008_2 1379698.RBG1_1C00001G1305 3.221e-308 982.0 COG0437@1|root,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria 2|Bacteria C 4Fe-4S dicluster domain actB - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_7,Molybdop_Fe4S4,Molydop_binding SYD1_k127_8725008_101 761193.Runsl_2962 4.565e-48 178.0 COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,47J8Z@768503|Cytophagia 976|Bacteroidetes C PFAM Class III cytochrome C family actA - - - - - - - - - - - Cytochrom_C,Cytochrom_CIII,Cytochrome_C7 SYD1_k127_8725008_109 1254432.SCE1572_34650 1.883e-40 159.0 COG2215@1|root,COG2215@2|Bacteria,1R3QK@1224|Proteobacteria 1224|Proteobacteria S Belongs to the NiCoT transporter (TC 2.A.52) family - - - - - - - - - - - - - SYD1_k127_8725008_81 644966.Tmar_1624 4.437e-61 230.0 COG1169@1|root,COG1169@2|Bacteria,1TSRT@1239|Firmicutes,24C67@186801|Clostridia 186801|Clostridia HQ PFAM Chorismate binding menF - 5.4.4.2 ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_bind SYD1_k127_8725008_35 479434.Sthe_3024 9.791e-140 466.0 COG1165@1|root,COG1165@2|Bacteria,2G6JR@200795|Chloroflexi,27XZC@189775|Thermomicrobia 189775|Thermomicrobia H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) menD - 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N SYD1_k127_8725008_82 309801.trd_A0259 6.438e-60 231.0 COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi,27Y8T@189775|Thermomicrobia 189775|Thermomicrobia I Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) menH - 4.2.99.20 ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08166 RC02148,RC02475 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 SYD1_k127_8725008_34 987059.RBXJA2T_13966 4.948e-140 451.0 COG0447@1|root,COG0447@2|Bacteria,1QTZ2@1224|Proteobacteria,2VJ36@28216|Betaproteobacteria,1KKKJ@119065|unclassified Burkholderiales 28216|Betaproteobacteria H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) menB - 4.1.3.36 ko:K01661,ko:K07536 ko00130,ko00362,ko01100,ko01110,ko01120,ko01220,map00130,map00362,map01100,map01110,map01120,map01220 M00116,M00540 R05592,R07263 RC01429,RC01923 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 SYD1_k127_8725008_68 383372.Rcas_2084 4.437e-81 279.0 COG1575@1|root,COG1575@2|Bacteria,2G5ZC@200795|Chloroflexi,376AE@32061|Chloroflexia 32061|Chloroflexia H Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA SYD1_k127_8725008_90 479434.Sthe_3017 5.475e-55 210.0 COG4948@1|root,COG4948@2|Bacteria,2G704@200795|Chloroflexi,27YF9@189775|Thermomicrobia 189775|Thermomicrobia H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) menC - - - - - - - - - - - MR_MLE_C,MR_MLE_N SYD1_k127_8725008_53 479434.Sthe_3015 2.153e-102 364.0 COG0318@1|root,COG0318@2|Bacteria,2G7PF@200795|Chloroflexi,27XJD@189775|Thermomicrobia 189775|Thermomicrobia IQ Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily menE - 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - AMP-binding,AMP-binding_C SYD1_k127_8725008_135 765912.Thimo_3316 3.811e-23 113.0 COG0824@1|root,COG0824@2|Bacteria,1N63F@1224|Proteobacteria,1SB06@1236|Gammaproteobacteria,1WYXM@135613|Chromatiales 135613|Chromatiales S PFAM thioesterase superfamily - - 3.1.2.28 ko:K12073 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07262 RC00004,RC00174 ko00000,ko00001,ko00002,ko01000 - - - 4HBT_2 SYD1_k127_8725008_73 1242864.D187_007601 4.755e-78 286.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2WNJ6@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran SYD1_k127_8725008_17 682795.AciX8_1792 1.961e-169 541.0 COG0821@1|root,COG0821@2|Bacteria,3Y2GU@57723|Acidobacteria,2JHND@204432|Acidobacteriia 204432|Acidobacteriia I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG - 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE SYD1_k127_8725008_87 215803.DB30_1826 6.832e-56 210.0 COG0451@1|root,COG0451@2|Bacteria,1PEGY@1224|Proteobacteria,4345A@68525|delta/epsilon subdivisions,2X3ZH@28221|Deltaproteobacteria,2YXPP@29|Myxococcales 28221|Deltaproteobacteria GM Polysaccharide biosynthesis protein - - - - - - - - - - - - Epimerase SYD1_k127_8725008_120 1288963.ADIS_3954 3.82e-32 133.0 COG2259@1|root,COG2259@2|Bacteria,4NSBJ@976|Bacteroidetes,47R97@768503|Cytophagia 976|Bacteroidetes S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX SYD1_k127_8725008_78 1379270.AUXF01000003_gene3710 2.175e-65 241.0 COG2859@1|root,COG2859@2|Bacteria,1ZUNC@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Protein of unknown function (DUF541) - - - ko:K09797 - - - - ko00000 - - - SIMPL SYD1_k127_8725008_99 1047013.AQSP01000101_gene615 4.251e-49 195.0 COG0845@1|root,COG0845@2|Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Gp58 SYD1_k127_8725008_167 762968.HMPREF9441_03717 3.807e-05 55.0 COG1073@1|root,COG1073@2|Bacteria,4NFJZ@976|Bacteroidetes,2FSC7@200643|Bacteroidia 976|Bacteroidetes S Dienelactone hydrolase family - - - ko:K06889 - - - - ko00000 - - - DLH,Hydrolase_4 SYD1_k127_8725008_150 1047013.AQSP01000137_gene541 1.047e-14 87.0 COG0726@1|root,COG4733@1|root,COG0726@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - - - - - - - - - - Polysacc_deac_1,Sulfotransfer_3 SYD1_k127_8790900_0 518766.Rmar_2008 1.65e-138 446.0 COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1FJ1P@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 ko:K00128,ko:K00135 ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130 M00027,M00135 R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh SYD1_k127_8790900_8 1459636.NTE_02825 3.025e-27 124.0 arCOG03383@1|root,arCOG03383@2157|Archaea 2157|Archaea E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40 SYD1_k127_8790900_1 880073.Calab_2175 4.349e-127 430.0 COG0488@1|root,COG0488@2|Bacteria,2NNPH@2323|unclassified Bacteria 2|Bacteria S ABC transporter yheS - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn SYD1_k127_8790900_3 1254432.SCE1572_02795 4.442e-104 379.0 COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales 28221|Deltaproteobacteria KLT Protein kinase domain - - - - - - - - - - - - Pkinase SYD1_k127_8790900_10 1120968.AUBX01000009_gene19 1.913e-13 82.0 COG1409@1|root,COG1409@2|Bacteria,4NEYU@976|Bacteroidetes,47KM8@768503|Cytophagia 976|Bacteroidetes S PFAM metallophosphoesterase - - - - - - - - - - - - Metallophos,Pur_ac_phosph_N SYD1_k127_8790900_11 448385.sce6264 4.877e-10 72.0 COG4775@1|root,COG4775@2|Bacteria 2|Bacteria M membrane organization - - - - - - - - - - - - Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA SYD1_k127_8790900_5 309807.SRU_0977 3.268e-74 275.0 2AB2F@1|root,310G6@2|Bacteria,4PEZP@976|Bacteroidetes,1FJWS@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes - - - - - - - - - - - - - - - SYD1_k127_8790900_4 448385.sce6263 1.037e-98 344.0 COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,438CB@68525|delta/epsilon subdivisions,2X3MN@28221|Deltaproteobacteria,2YWIY@29|Myxococcales 28221|Deltaproteobacteria C ATP ADP translocase - - - ko:K03301 - - - - ko00000 2.A.12 - - - SYD1_k127_8790900_2 448385.sce6976 5.37e-115 402.0 COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria 2|Bacteria C ATP:ADP antiporter activity - - - ko:K01932,ko:K03301 - - - - ko00000,ko01000 2.A.12 - - Glyco_transf_4,Glycos_transf_1,HEAT_2,TLC SYD1_k127_8790900_6 251221.35213116 1.66e-63 248.0 COG0793@1|root,COG0793@2|Bacteria,1G58N@1117|Cyanobacteria 1117|Cyanobacteria M N-terminal domain of Peptidase_S41 in eukaryotic IRBP - - - - - - - - - - - - Peptidase_S41,Peptidase_S41_N SYD1_k127_8790900_9 1121931.AUHG01000015_gene1241 1.356e-24 113.0 COG1595@1|root,COG1595@2|Bacteria,4NSVA@976|Bacteroidetes,1I0Q1@117743|Flavobacteriia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SYD1_k127_8790900_7 1168034.FH5T_04765 6.025e-53 194.0 COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,2FNI4@200643|Bacteroidia 976|Bacteroidetes E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase SYD1_k127_8842826_27 589865.DaAHT2_1904 6.098e-30 122.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,42MQ4@68525|delta/epsilon subdivisions,2WMDT@28221|Deltaproteobacteria,2MHNR@213118|Desulfobacterales 28221|Deltaproteobacteria S TIGRFAM competence damage-inducible protein CinA cinA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth SYD1_k127_8842826_28 292459.STH1664 9.547e-30 130.0 COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,24MTR@186801|Clostridia 186801|Clostridia J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ligT - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase SYD1_k127_8842826_2 635013.TherJR_1277 2.393e-150 486.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,260U5@186807|Peptococcaceae 186801|Clostridia L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA SYD1_k127_8842826_34 479434.Sthe_1432 2.555e-12 74.0 COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi,27YM4@189775|Thermomicrobia 189775|Thermomicrobia S RecX family recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX SYD1_k127_8842826_0 644966.Tmar_1223 1.474e-215 706.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WCF6@538999|Clostridiales incertae sedis 186801|Clostridia J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD SYD1_k127_8842826_25 517418.Ctha_0722 1.344e-35 158.0 COG1646@1|root,COG1646@2|Bacteria,1FEV5@1090|Chlorobi 1090|Chlorobi I PcrB family - - - ko:K07094 - - - - ko00000,ko01000 - - - PcrB SYD1_k127_8842826_4 671143.DAMO_2778 3.911e-137 447.0 COG1209@1|root,COG1209@2|Bacteria,2NNTJ@2323|unclassified Bacteria 2|Bacteria M Nucleotidyl transferase rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase SYD1_k127_8842826_16 330214.NIDE3014 4.508e-61 234.0 COG1091@1|root,COG1091@2|Bacteria,3J0SU@40117|Nitrospirae 40117|Nitrospirae M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind SYD1_k127_8842826_21 1380394.JADL01000004_gene5973 4.136e-45 183.0 COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VF0J@28211|Alphaproteobacteria,2JYN6@204441|Rhodospirillales 204441|Rhodospirillales G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate - - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 SYD1_k127_8842826_14 1379698.RBG1_1C00001G1327 2.906e-67 248.0 COG0382@1|root,COG0382@2|Bacteria,2NNVJ@2323|unclassified Bacteria 2|Bacteria H UbiA prenyltransferase family ubiA - - - - - - - - - - - UbiA SYD1_k127_8842826_20 292459.STH3246 4.514e-46 188.0 COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia 186801|Clostridia I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE - 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N SYD1_k127_8842826_30 1379698.RBG1_1C00001G0639 4.885e-26 109.0 COG2088@1|root,COG2088@2|Bacteria,2NQ05@2323|unclassified Bacteria 2|Bacteria D SpoVG spoVG - - ko:K06412 - - - - ko00000 - - - SpoVG SYD1_k127_8842826_9 1121472.AQWN01000007_gene1176 6.356e-109 362.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,2605Q@186807|Peptococcaceae 186801|Clostridia F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N SYD1_k127_8842826_17 1379698.RBG1_1C00001G0172 1.223e-56 205.0 COG1825@1|root,COG1825@2|Bacteria,2NPVU@2323|unclassified Bacteria 2|Bacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C SYD1_k127_8842826_23 484770.UFO1_4295 7.834e-42 161.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4H4AW@909932|Negativicutes 909932|Negativicutes J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro SYD1_k127_8842826_32 671143.DAMO_0510 2.652e-18 89.0 COG0360@1|root,COG0360@2|Bacteria,2NQ1Q@2323|unclassified Bacteria 2|Bacteria J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 4.3.1.19 ko:K01754,ko:K02990 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,ko03010,map00260,map00290,map01100,map01110,map01130,map01200,map01230,map03010 M00178,M00570 R00220,R00996 RC00418,RC02600 br01610,ko00000,ko00001,ko00002,ko01000,ko03011,ko03029 - - - Ribosomal_S6 SYD1_k127_8842826_31 999411.HMPREF1092_02707 3.137e-23 101.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,36KGE@31979|Clostridiaceae 186801|Clostridia J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR - - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 SYD1_k127_8842826_38 177437.HRM2_18620 0.0003753 52.0 COG4241@1|root,COG4241@2|Bacteria,1N4XJ@1224|Proteobacteria,42QCS@68525|delta/epsilon subdivisions,2WKDT@28221|Deltaproteobacteria,2MIFQ@213118|Desulfobacterales 28221|Deltaproteobacteria S Predicted membrane protein (DUF2232) - - - - - - - - - - - - DUF2232 SYD1_k127_8842826_26 1379698.RBG1_1C00001G0130 5.066e-30 135.0 COG0359@1|root,COG0359@2|Bacteria,2NPX4@2323|unclassified Bacteria 2|Bacteria J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N SYD1_k127_8842826_33 1304885.AUEY01000019_gene1175 3.891e-14 86.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria,2MNB1@213118|Desulfobacterales 28221|Deltaproteobacteria M peptidylprolyl isomerase - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 SYD1_k127_8842826_36 1122176.KB903554_gene3803 6.943e-07 62.0 COG1729@1|root,COG1729@2|Bacteria 2|Bacteria S protein trimerization - - - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - LysM,TPR_16,TPR_6,YfiO SYD1_k127_8842826_24 1379698.RBG1_1C00001G0129 1.143e-39 154.0 COG1259@1|root,COG1259@2|Bacteria,2NP7X@2323|unclassified Bacteria 2|Bacteria S Bifunctional nuclease - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K03617,ko:K08999 - - - - ko00000 - - - DNase-RNase,UVR SYD1_k127_8842826_22 330214.NIDE0301 1.015e-42 166.0 COG0663@1|root,COG0663@2|Bacteria,3J121@40117|Nitrospirae 40117|Nitrospirae S Bacterial transferase hexapeptide (six repeats) - - - - - - - - - - - - Hexapep SYD1_k127_8842826_35 1121918.ARWE01000001_gene3464 3.866e-07 63.0 COG0683@1|root,COG0683@2|Bacteria,1R8IG@1224|Proteobacteria,42N7H@68525|delta/epsilon subdivisions,2WIUQ@28221|Deltaproteobacteria,43S82@69541|Desulfuromonadales 28221|Deltaproteobacteria E LppC putative lipoprotein - - - ko:K07121 - - - - ko00000 - - - LppC,Peripla_BP_6,TPR_16,TPR_6 SYD1_k127_8842826_5 1379698.RBG1_1C00001G1351 6.723e-133 440.0 COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria 2|Bacteria E Receptor family ligand binding region livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 SYD1_k127_8842826_6 1379698.RBG1_1C00001G1350 6.044e-117 383.0 COG0559@1|root,COG0559@2|Bacteria,2NP7Z@2323|unclassified Bacteria 2|Bacteria E Branched-chain amino acid transport system / permease component livH - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 SYD1_k127_8842826_8 1379698.RBG1_1C00001G1349 2.382e-110 366.0 COG4177@1|root,COG4177@2|Bacteria,2NPMP@2323|unclassified Bacteria 2|Bacteria U Branched-chain amino acid transport system / permease component - - - ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 SYD1_k127_8842826_12 644966.Tmar_0651 6.503e-82 295.0 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,3WCU3@538999|Clostridiales incertae sedis 186801|Clostridia E Amino acid amide ABC transporter ATP-binding protein 1, HAAT family livG - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C SYD1_k127_8842826_10 525904.Tter_0589 5.071e-91 309.0 COG0410@1|root,COG0410@2|Bacteria,2NNXF@2323|unclassified Bacteria 2|Bacteria E ABC transporter livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran SYD1_k127_8842826_7 1125863.JAFN01000001_gene282 3.772e-116 400.0 COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis selA GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - Se-cys_synth_N,SelA SYD1_k127_8842826_37 300852.55773040 0.0002307 53.0 COG3147@1|root,COG3147@2|Bacteria,1WJ2W@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM Sporulation related domain - - - - - - - - - - - - SPOR SYD1_k127_8842826_1 518766.Rmar_0643 1.822e-171 584.0 COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,1FIP5@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge SYD1_k127_8842826_11 871963.Desdi_2656 4.012e-88 301.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,260N3@186807|Peptococcaceae 186801|Clostridia U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N SYD1_k127_8842826_29 396588.Tgr7_0719 1.681e-26 124.0 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1SZ82@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Protein of unknown function, DUF484 - - - - - - - - - - - - DUF484,GGDEF SYD1_k127_8842826_18 1121456.ATVA01000015_gene2310 6.229e-56 221.0 COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria,2M91P@213115|Desulfovibrionales 28221|Deltaproteobacteria T PFAM sigma-54 factor interaction domain-containing protein - - - ko:K02584 ko02020,map02020 - - - ko00000,ko00001,ko03000 - - - GAF,GAF_2,HTH_8,Sigma54_activat SYD1_k127_8842826_19 671143.DAMO_1604 3.873e-54 193.0 COG1143@1|root,COG1143@2|Bacteria,2NPQR@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 ko:K00337,ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iNJ661.Rv3153 Fer4 SYD1_k127_8842826_15 671143.DAMO_0448 1.11e-62 224.0 COG0428@1|root,COG0428@2|Bacteria,2NQ6J@2323|unclassified Bacteria 2|Bacteria P ZIP Zinc transporter zupT - - ko:K07238,ko:K11021,ko:K16267 - - - - ko00000,ko02000,ko02042 2.A.5.4.11,2.A.5.5 - - Zip SYD1_k127_8842826_13 656024.FsymDg_4006 2.058e-75 256.0 COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4ERM4@85013|Frankiales 201174|Actinobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 SYD1_k127_8842826_3 671143.DAMO_2698 1.199e-149 486.0 COG0649@1|root,COG0649@2|Bacteria,2NNWG@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa SYD1_k127_8843715_2 1123368.AUIS01000028_gene1310 2.269e-75 272.0 COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,1S4SH@1236|Gammaproteobacteria,2NCF7@225057|Acidithiobacillales 225057|Acidithiobacillales MU CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - - - - - - - - - - OEP SYD1_k127_8843715_1 861299.J421_6126 5.671e-82 286.0 COG0845@1|root,COG0845@2|Bacteria,1ZTJD@142182|Gemmatimonadetes 142182|Gemmatimonadetes M Biotin-lipoyl like - - - ko:K07799 ko02020,map02020 M00648 - - ko00000,ko00001,ko00002,ko02000 8.A.1 - - Biotin_lipoyl_2,HlyD_3 SYD1_k127_8843715_0 379066.GAU_0522 0.0 1157.0 COG0841@1|root,COG0841@2|Bacteria,1ZT98@142182|Gemmatimonadetes 142182|Gemmatimonadetes V MMPL family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran SYD1_k127_8843715_3 794903.OPIT5_19275 4.569e-25 104.0 COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,46VST@74201|Verrucomicrobia,3K7DE@414999|Opitutae 414999|Opitutae C NADH ubiquinone oxidoreductase, 20 Kd subunit - - - - - - - - - - - - Fer4,Oxidored_q6 SYD1_k127_9109170_47 1047013.AQSP01000059_gene2099 1.872e-18 93.0 COG1028@1|root,COG1028@2|Bacteria,2NPQY@2323|unclassified Bacteria 2|Bacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SYD1_k127_9109170_30 1184251.TCELL_1317 9.414e-52 187.0 COG1839@1|root,arCOG04298@2157|Archaea,2XQ7K@28889|Crenarchaeota 28889|Crenarchaeota L PFAM Adenosine specific kinase - - - ko:K09129 - - - - ko00000 - - - Adenosine_kin SYD1_k127_9109170_6 880073.Calab_3657 9.467e-142 469.0 COG0608@1|root,COG0608@2|Bacteria,2NNRX@2323|unclassified Bacteria 2|Bacteria L single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 SYD1_k127_9109170_0 1382304.JNIL01000001_gene1053 1.212e-197 653.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,27890@186823|Alicyclobacillaceae 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS SYD1_k127_9109170_39 42256.RradSPS_0525 7.772e-40 170.0 COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,4CQCM@84995|Rubrobacteria 84995|Rubrobacteria J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd - - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase SYD1_k127_9109170_35 398767.Glov_0462 2.977e-44 168.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2WP65@28221|Deltaproteobacteria,43UWG@69541|Desulfuromonadales 28221|Deltaproteobacteria D PFAM Maf family protein maf - - ko:K06287 - - - - ko00000 - - - Maf SYD1_k127_9109170_14 867903.ThesuDRAFT_00760 1.481e-86 313.0 COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,3WCG0@538999|Clostridiales incertae sedis 186801|Clostridia J Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B SYD1_k127_9109170_29 883109.HMPREF0380_00121 6.651e-54 193.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,3WD6S@538999|Clostridiales incertae sedis 186801|Clostridia J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM - - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 SYD1_k127_9109170_41 546273.VEIDISOL_00514 3.524e-34 135.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4H4GK@909932|Negativicutes 909932|Negativicutes J Belongs to the universal ribosomal protein uS9 family rpsI - - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 SYD1_k127_9109170_13 1382305.AZUC01000047_gene951 3.608e-89 302.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,26DJF@186818|Planococcaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 SYD1_k127_9109170_22 1089553.Tph_c11150 2.883e-70 246.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,42EMG@68295|Thermoanaerobacterales 186801|Clostridia J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS SYD1_k127_9109170_16 1162668.LFE_2150 2.425e-82 289.0 COG0528@1|root,COG0528@2|Bacteria,3J0BE@40117|Nitrospirae 40117|Nitrospirae F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase SYD1_k127_9109170_25 1379698.RBG1_1C00001G1020 1.504e-60 216.0 COG0233@1|root,COG0233@2|Bacteria,2NPEP@2323|unclassified Bacteria 2|Bacteria J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF SYD1_k127_9109170_20 1123277.KB893172_gene679 2.348e-74 259.0 COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,47MC0@768503|Cytophagia 976|Bacteroidetes I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf SYD1_k127_9109170_34 1379698.RBG1_1C00001G1022 2.674e-44 174.0 COG4589@1|root,COG4589@2|Bacteria,2NPVB@2323|unclassified Bacteria 2|Bacteria S Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 SYD1_k127_9109170_11 1125863.JAFN01000001_gene964 5.477e-101 341.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2WK14@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom SYD1_k127_9109170_23 401526.TcarDRAFT_1319 1.827e-61 237.0 COG2870@1|root,COG2870@2|Bacteria,1TSMF@1239|Firmicutes,4H1UR@909932|Negativicutes 909932|Negativicutes M Bifunctional protein rfaE - - - - - - - - - - - CTP_transf_like,PfkB SYD1_k127_9109170_42 246197.MXAN_4709 7.813e-32 142.0 COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose rfaE - - - - - - - - - - - CTP_transf_like SYD1_k127_9109170_37 671143.DAMO_0272 4.972e-42 168.0 COG0859@1|root,COG3307@1|root,COG0859@2|Bacteria,COG3307@2|Bacteria,2NP5P@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferase, family 9 rfaQ - - ko:K02841,ko:K02843,ko:K02847,ko:K02849,ko:K21003 ko00540,ko01100,ko02025,map00540,map01100,map02025 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000 9.B.67.4,9.B.67.5 GT9 - Glyco_transf_25,Glyco_transf_9,Wzy_C SYD1_k127_9109170_32 903818.KI912269_gene362 2.294e-46 184.0 COG0859@1|root,COG0859@2|Bacteria 2|Bacteria M ADP-heptose-lipopolysaccharide heptosyltransferase activity rfaQ - - ko:K02841,ko:K02843,ko:K02849 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 SYD1_k127_9109170_28 1122176.KB903551_gene4232 1.125e-56 220.0 COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,1IU82@117747|Sphingobacteriia 976|Bacteroidetes M involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 SYD1_k127_9109170_33 479434.Sthe_0849 1.163e-45 188.0 COG0438@1|root,COG0438@2|Bacteria,2G8W3@200795|Chloroflexi,27Y3X@189775|Thermomicrobia 189775|Thermomicrobia M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4 SYD1_k127_9109170_24 1047013.AQSP01000138_gene1051 8.429e-61 235.0 COG0438@1|root,COG0438@2|Bacteria,2NPA0@2323|unclassified Bacteria 2|Bacteria M glycosyl transferase group 1 - - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 SYD1_k127_9109170_27 1379698.RBG1_1C00001G0616 6.121e-60 222.0 COG4412@1|root,COG4412@2|Bacteria 2|Bacteria S peptidase activity, acting on L-amino acid peptides - - - - - - - - - - - - F5_F8_type_C,Peptidase_M6 SYD1_k127_9109170_19 459349.CLOAM1502 1.336e-75 271.0 COG0750@1|root,COG0750@2|Bacteria,2NP7C@2323|unclassified Bacteria 2|Bacteria M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 SYD1_k127_9109170_31 644282.Deba_2109 1.006e-49 200.0 COG4775@1|root,COG5616@1|root,COG4775@2|Bacteria,COG5616@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA SYD1_k127_9109170_50 335543.Sfum_0830 2.543e-16 95.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,42PSZ@68525|delta/epsilon subdivisions,2WMBH@28221|Deltaproteobacteria,2MS6R@213462|Syntrophobacterales 28221|Deltaproteobacteria S Pfam:DUF490 - - - ko:K09800 - - - - ko00000,ko02000 - - - TamB SYD1_k127_9109170_1 370438.PTH_2529 2.881e-179 585.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,260F2@186807|Peptococcaceae 186801|Clostridia L PFAM UvrD REP helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C SYD1_k127_9109170_48 163908.KB235896_gene2601 9.535e-18 85.0 COG0721@1|root,COG0721@2|Bacteria,1G7N8@1117|Cyanobacteria,1HP1J@1161|Nostocales 1117|Cyanobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln SYD1_k127_9109170_4 1121468.AUBR01000017_gene2371 1.413e-164 535.0 COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,42EXF@68295|Thermoanaerobacterales 186801|Clostridia J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase SYD1_k127_9109170_3 243231.GSU3380 8.375e-165 556.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey SYD1_k127_9109170_10 648996.Theam_0942 5.645e-114 389.0 COG0151@1|root,COG0151@2|Bacteria,2G3J3@200783|Aquificae 200783|Aquificae F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N SYD1_k127_9109170_40 192222.Cj0702 8.836e-38 162.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2YNW0@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC SYD1_k127_9109170_46 1504822.CCNO01000008_gene1945 1.372e-19 96.0 COG0009@1|root,COG0009@2|Bacteria 2|Bacteria J L-threonylcarbamoyladenylate synthase prmC - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC SYD1_k127_9109170_43 429009.Adeg_0069 1.747e-25 112.0 COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia,42GVA@68295|Thermoanaerobacterales 186801|Clostridia T PFAM Protein-tyrosine phosphatase, low molecular weight ywlE - 3.1.3.48,3.9.1.2 ko:K01104,ko:K20201 - - - - ko00000,ko01000 - - - LMWPc SYD1_k127_9109170_9 1128421.JAGA01000001_gene2171 1.994e-115 389.0 COG0115@1|root,COG0115@2|Bacteria,2NP1Q@2323|unclassified Bacteria 2|Bacteria E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 SYD1_k127_9109170_2 644966.Tmar_0757 9.732e-174 554.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3WCFT@538999|Clostridiales incertae sedis 186801|Clostridia E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT SYD1_k127_9109170_8 1278073.MYSTI_06258 9.405e-121 396.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YUJY@29|Myxococcales 28221|Deltaproteobacteria S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 SYD1_k127_9109170_21 313596.RB2501_07630 2.417e-71 264.0 COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,1HX4X@117743|Flavobacteriia 976|Bacteroidetes S protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 SYD1_k127_9109170_18 1379698.RBG1_1C00001G1775 2.564e-77 284.0 COG2304@1|root,COG2304@2|Bacteria,2NNYH@2323|unclassified Bacteria 2|Bacteria NU von Willebrand factor (vWF) type A domain batA - - ko:K07114,ko:K12511 - - - - ko00000,ko02000,ko02044 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA SYD1_k127_9109170_36 1144275.COCOR_06151 6.627e-43 169.0 COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2YV46@29|Myxococcales 28221|Deltaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain batB - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,TPR_1,TPR_16,TPR_2,VWA,VWA_2 SYD1_k127_9109170_54 518766.Rmar_0440 5.266e-05 54.0 COG0457@1|root,COG0457@2|Bacteria,4PK18@976|Bacteroidetes,1FJN0@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - SYD1_k127_9109170_45 517418.Ctha_2592 6.78e-21 108.0 COG0457@1|root,COG0457@2|Bacteria,1FE6Q@1090|Chlorobi 1090|Chlorobi S Oxygen tolerance - - - - - - - - - - - - BatD SYD1_k127_9109170_51 246197.MXAN_5659 1.835e-09 71.0 COG0457@1|root,COG0457@2|Bacteria,1NK0T@1224|Proteobacteria,42X28@68525|delta/epsilon subdivisions,2WT4A@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - SYD1_k127_9109170_38 278963.ATWD01000002_gene779 9.728e-41 172.0 COG4221@1|root,COG4221@2|Bacteria,3Y6ZB@57723|Acidobacteria,2JKUG@204432|Acidobacteriia 204432|Acidobacteriia S KR domain - - - - - - - - - - - - adh_short SYD1_k127_9109170_5 251221.35211608 2.461e-155 514.0 COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria 1117|Cyanobacteria O Belongs to the deoxyhypusine synthase family - - 2.5.1.46 ko:K00809 - - - - ko00000,ko01000 - - - DS SYD1_k127_9109170_15 1128421.JAGA01000002_gene736 2.433e-86 313.0 COG0399@1|root,COG0399@2|Bacteria,2NNS2@2323|unclassified Bacteria 2|Bacteria E Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 SYD1_k127_9109170_53 1379698.RBG1_1C00001G1516 1.211e-05 59.0 COG2982@1|root,COG2982@2|Bacteria,2NRT5@2323|unclassified Bacteria 2|Bacteria M AsmA-like C-terminal region - - - ko:K07289,ko:K09800 - - - - ko00000,ko02000 - - - AsmA,AsmA_1,AsmA_2,DUF3971,DctA-YdbH SYD1_k127_9109170_12 1210884.HG799462_gene8380 2.814e-98 353.0 COG1131@1|root,COG1131@2|Bacteria,2IZYW@203682|Planctomycetes 203682|Planctomycetes V ABC transporter - - - - - - - - - - - - ABC_tran,DUF4162 SYD1_k127_9109170_17 1379698.RBG1_1C00001G0602 1.773e-77 283.0 COG0842@1|root,COG0842@2|Bacteria,2NQCU@2323|unclassified Bacteria 2|Bacteria V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane SYD1_k127_9109170_26 926569.ANT_06940 2.366e-60 230.0 COG0842@1|root,COG0842@2|Bacteria,2G8MV@200795|Chloroflexi 200795|Chloroflexi V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane SYD1_k127_9109170_49 243231.GSU1057 2.095e-16 86.0 COG0457@1|root,COG0457@2|Bacteria,1P22J@1224|Proteobacteria,4310H@68525|delta/epsilon subdivisions,2WWBW@28221|Deltaproteobacteria,43VHQ@69541|Desulfuromonadales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - SYD1_k127_9109170_44 1242864.D187_002011 4.162e-23 105.0 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria,2YVHR@29|Myxococcales 28221|Deltaproteobacteria G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 ptsN - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 SYD1_k127_9109170_52 1408428.JNJP01000024_gene3760 2.532e-07 59.0 COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2WKVG@28221|Deltaproteobacteria,2M888@213115|Desulfovibrionales 28221|Deltaproteobacteria S C4-type zinc ribbon domain - - - ko:K07164 - - - - ko00000 - - - zf-RING_7 SYD1_k127_9109170_7 1379698.RBG1_1C00001G1345 4.257e-129 442.0 COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria 2|Bacteria KT COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit rsbU - 3.1.3.3,4.6.1.1 ko:K01768,ko:K07315 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko03021 - - - GAF,GAF_2,HATPase_c_2,SSF,SpoIIE ## 2564 queries scanned ## Total time (seconds): 317.46339678764343 ## Rate: 8.08 q/s