## Fri Nov 15 23:34:04 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin25/SYD_2_bin.10.fa -m mmseqs --itype genome -o SYD_2_bin.10 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/SYD_2_bin.10 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SYD2_k127_1008767_0	204669.Acid345_2136	5.678e-209	687.0	COG1629@1|root,COG1629@2|Bacteria,3Y2K8@57723|Acidobacteria,2JKEC@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SYD2_k127_1008767_1	593117.TGAM_0391	3.91e-65	234.0	COG1820@1|root,arCOG00699@2157|Archaea,2Y3HD@28890|Euryarchaeota	28890|Euryarchaeota	G	Amidohydrolase family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SYD2_k127_1014150_1	497964.CfE428DRAFT_5266	1.024e-33	134.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
SYD2_k127_1014150_0	1173024.KI912149_gene5854	7.223e-171	554.0	COG0457@1|root,COG0457@2|Bacteria,1GDHI@1117|Cyanobacteria	1117|Cyanobacteria	S	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1030345_1	1121920.AUAU01000013_gene1715	6.226e-37	147.0	COG1629@1|root,COG4771@2|Bacteria,3Y36N@57723|Acidobacteria	57723|Acidobacteria	P	PFAM TonB-dependent Receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
SYD2_k127_1030345_0	330214.NIDE3251	2.614e-179	582.0	COG3696@1|root,COG3696@2|Bacteria	2|Bacteria	P	silver ion transport	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
SYD2_k127_103425_0	204669.Acid345_2141	4.915e-142	458.0	COG2133@1|root,COG2133@2|Bacteria,3Y98P@57723|Acidobacteria,2JP56@204432|Acidobacteriia	204432|Acidobacteriia	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1037606_3	1121007.AUML01000005_gene2323	1.796e-09	62.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,1HYCJ@117743|Flavobacteriia,2YIJJ@290174|Aquimarina	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SYD2_k127_1037606_4	401526.TcarDRAFT_2085	0.0001368	47.0	COG1758@1|root,COG1758@2|Bacteria,1VK74@1239|Firmicutes,4H5NB@909932|Negativicutes	909932|Negativicutes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SYD2_k127_1037606_1	521045.Kole_1848	1.02e-51	192.0	COG0194@1|root,COG0194@2|Bacteria,2GD0U@200918|Thermotogae	200918|Thermotogae	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SYD2_k127_1037606_2	1121403.AUCV01000001_gene915	2.467e-28	116.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,42RFR@68525|delta/epsilon subdivisions,2WJYK@28221|Deltaproteobacteria,2MIFF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
SYD2_k127_1047903_4	234267.Acid_5675	1.252e-53	192.0	COG0535@1|root,COG0535@2|Bacteria,3Y3QA@57723|Acidobacteria	57723|Acidobacteria	S	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SYD2_k127_1047903_2	278963.ATWD01000001_gene1477	3.501e-124	414.0	COG0469@1|root,COG0469@2|Bacteria,3Y36V@57723|Acidobacteria,2JHY5@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SYD2_k127_1047903_8	204669.Acid345_2015	1.202e-26	117.0	COG2006@1|root,COG2006@2|Bacteria,3Y7N1@57723|Acidobacteria,2JNKP@204432|Acidobacteriia	204432|Acidobacteriia	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SYD2_k127_1047903_0	945713.IALB_2638	8.905e-183	590.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SYD2_k127_1047903_1	1267534.KB906756_gene561	1.39e-178	577.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria,2JIBZ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
SYD2_k127_1047903_5	401526.TcarDRAFT_0275	7.157e-42	173.0	COG2199@1|root,COG3706@2|Bacteria,1V469@1239|Firmicutes,4H4YE@909932|Negativicutes	909932|Negativicutes	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,PAS_9
SYD2_k127_1047903_10	1472716.KBK24_0126425	3.2e-16	83.0	COG2050@1|root,COG2050@2|Bacteria,1RKWK@1224|Proteobacteria,2VSST@28216|Betaproteobacteria,1K7CQ@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SYD2_k127_1047903_6	316274.Haur_0239	1.418e-39	151.0	COG0393@1|root,COG0393@2|Bacteria	2|Bacteria	S	Putative heavy-metal-binding	ybjQ	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
SYD2_k127_1047903_9	937777.Deipe_2668	2.551e-24	106.0	COG3695@1|root,COG3695@2|Bacteria	2|Bacteria	L	enzyme binding	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,YjbR
SYD2_k127_1047903_3	269799.Gmet_0042	2.117e-54	198.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,42SY1@68525|delta/epsilon subdivisions,2WPQ7@28221|Deltaproteobacteria,43V12@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
SYD2_k127_1047903_7	204669.Acid345_3342	1.055e-33	136.0	COG1427@1|root,COG1427@2|Bacteria,3Y3PU@57723|Acidobacteria,2JIWB@204432|Acidobacteriia	204432|Acidobacteriia	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SYD2_k127_1062641_0	234267.Acid_5219	1.493e-60	214.0	COG1595@1|root,COG1595@2|Bacteria,3Y7YB@57723|Acidobacteria	2|Bacteria	K	RNA polymerase, sigma-24 subunit, ECF subfamily	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
SYD2_k127_1062641_1	1267534.KB906758_gene2500	5.348e-08	64.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,VCBS
SYD2_k127_1062641_2	870187.Thini_0124	0.0003357	51.0	COG0823@1|root,COG2304@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG4932@1|root,COG4935@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,COG4932@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	cglB	-	-	ko:K12287,ko:K12516,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000,ko02044	1.B.12.5.5	-	-	Beta_helix,DUF3494,HemolysinCabind
SYD2_k127_1083226_0	1340493.JNIF01000003_gene3063	5.182e-224	722.0	COG0587@1|root,COG0587@2|Bacteria,3Y2TS@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SYD2_k127_1083226_2	1121920.AUAU01000001_gene2276	6.059e-105	347.0	COG0825@1|root,COG0825@2|Bacteria,3Y34D@57723|Acidobacteria	57723|Acidobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SYD2_k127_1083226_7	983917.RGE_46350	8.155e-39	149.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,1KKNH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SYD2_k127_1083226_3	1046714.AMRX01000007_gene2076	1.8e-102	349.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,4643J@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SYD2_k127_1083226_6	204669.Acid345_1875	3.758e-50	183.0	COG1259@1|root,COG1259@2|Bacteria,3Y4QD@57723|Acidobacteria,2JJ7J@204432|Acidobacteriia	204432|Acidobacteriia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SYD2_k127_1083226_4	1047013.AQSP01000134_gene1378	3.756e-88	297.0	COG1192@1|root,COG1192@2|Bacteria,2NP2C@2323|unclassified Bacteria	2|Bacteria	D	Cobyrinic acid ac-diamide synthase	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SYD2_k127_1083226_5	1047013.AQSP01000134_gene1379	1.431e-61	221.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SYD2_k127_1083226_1	1198114.AciX9_0753	1.476e-118	387.0	COG0192@1|root,COG0192@2|Bacteria,3Y45C@57723|Acidobacteria,2JJ0A@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SYD2_k127_1091438_2	316274.Haur_0016	4.57e-105	348.0	COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi,376HN@32061|Chloroflexia	200795|Chloroflexi	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SYD2_k127_1091438_6	264462.Bd2405	4.061e-07	62.0	COG4254@1|root,COG4254@2|Bacteria,1QVB5@1224|Proteobacteria,42XP1@68525|delta/epsilon subdivisions,2MUHH@213481|Bdellovibrionales,2X71D@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SYD2_k127_1091438_4	351607.Acel_0165	1.008e-42	176.0	COG2199@1|root,COG2203@1|root,COG5000@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG5000@2|Bacteria,2IA4H@201174|Actinobacteria	201174|Actinobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HAMP
SYD2_k127_1091438_0	401053.AciPR4_0872	2.148e-174	551.0	COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria,2JHQ2@204432|Acidobacteriia	204432|Acidobacteriia	D	cell shape determining protein MreB	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SYD2_k127_1091438_5	1121423.JONT01000001_gene1921	7.346e-29	127.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,260H4@186807|Peptococcaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SYD2_k127_1091438_7	926566.Terro_3277	3.593e-05	53.0	2CM1I@1|root,32SDF@2|Bacteria,3Y571@57723|Acidobacteria,2JJRW@204432|Acidobacteriia	204432|Acidobacteriia	S	shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
SYD2_k127_1091438_1	204669.Acid345_1465	3.045e-115	395.0	COG0768@1|root,COG0768@2|Bacteria,3Y3MX@57723|Acidobacteria,2JHRD@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein, dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SYD2_k127_1091438_3	639030.JHVA01000001_gene3407	3.144e-55	206.0	COG0772@1|root,COG0772@2|Bacteria,3Y3DZ@57723|Acidobacteria,2JINX@204432|Acidobacteriia	204432|Acidobacteriia	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SYD2_k127_1125176_6	429009.Adeg_1137	2.969e-130	423.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,42EYV@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
SYD2_k127_1125176_20	56780.SYN_00927	4.898e-15	81.0	COG1426@1|root,COG1426@2|Bacteria,1Q29D@1224|Proteobacteria,437BA@68525|delta/epsilon subdivisions,2WS2J@28221|Deltaproteobacteria,2MQQ8@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SYD2_k127_1125176_14	1519464.HY22_04930	3.225e-37	144.0	COG4577@1|root,COG4577@2|Bacteria,1FFDI@1090|Chlorobi	1090|Chlorobi	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
SYD2_k127_1125176_4	1511.CLOST_0251	1.908e-139	463.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,25E5E@186801|Clostridia	186801|Clostridia	C	acetaldehyde dehydrogenase (acetylating)	eutE	-	1.2.1.10,1.2.1.76,1.2.1.81,1.2.1.87	ko:K00132,ko:K13922,ko:K15515,ko:K18119	ko00620,ko00640,ko00650,ko01100,ko01120,ko01200,map00620,map00640,map00650,map01100,map01120,map01200	-	R00228,R01172,R09097,R09280	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
SYD2_k127_1125176_16	880073.Calab_3249	7.513e-27	113.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
SYD2_k127_1125176_19	1121472.AQWN01000002_gene2136	8.224e-19	92.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia,262HN@186807|Peptococcaceae	186801|Clostridia	T	Belongs to the UPF0237 family	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
SYD2_k127_1125176_3	429009.Adeg_1269	4.732e-176	562.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia,42EYH@68295|Thermoanaerobacterales	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
SYD2_k127_1125176_15	1499967.BAYZ01000012_gene2485	3.097e-29	120.0	COG4577@1|root,COG4577@2|Bacteria,2NRBW@2323|unclassified Bacteria	2|Bacteria	CQ	COGs COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
SYD2_k127_1125176_18	269084.syc2277_d	7.145e-26	111.0	COG0745@1|root,COG0745@2|Bacteria,1G6W5@1117|Cyanobacteria,1H0QZ@1129|Synechococcus	1117|Cyanobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SYD2_k127_1125176_8	204669.Acid345_2300	4.474e-108	380.0	COG5316@1|root,COG5316@2|Bacteria,3Y46P@57723|Acidobacteria,2JMJ4@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
SYD2_k127_1125176_2	373994.Riv7116_5866	4.042e-201	640.0	COG0477@1|root,COG0477@2|Bacteria,1GJ8D@1117|Cyanobacteria,1HSV0@1161|Nostocales	1117|Cyanobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1125176_23	314230.DSM3645_29546	7.551e-05	55.0	2EQD5@1|root,33HZ7@2|Bacteria,2J1EC@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1125176_21	1340493.JNIF01000004_gene952	1.06e-05	57.0	COG0671@1|root,COG1075@1|root,COG0671@2|Bacteria,COG1075@2|Bacteria,3Y7BS@57723|Acidobacteria	57723|Acidobacteria	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
SYD2_k127_1125176_1	886293.Sinac_1501	4.971e-216	691.0	COG3591@1|root,COG3591@2|Bacteria,2IXPD@203682|Planctomycetes	203682|Planctomycetes	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
SYD2_k127_1125176_17	357808.RoseRS_0076	4.073e-26	114.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G5K6@200795|Chloroflexi,376BY@32061|Chloroflexia	32061|Chloroflexia	L	Helix-hairpin-helix DNA-binding, class 1	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SYD2_k127_1125176_10	204669.Acid345_2506	8.249e-67	243.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SYD2_k127_1125176_12	1382359.JIAL01000001_gene1085	1.867e-44	177.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SYD2_k127_1125176_7	497964.CfE428DRAFT_2318	5.304e-109	360.0	COG0664@1|root,COG4420@1|root,COG0664@2|Bacteria,COG4420@2|Bacteria,46T5T@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003,cNMP_binding
SYD2_k127_1125176_5	234267.Acid_6457	2.8e-130	428.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
SYD2_k127_1125176_13	1469607.KK073768_gene2261	3.91e-38	150.0	COG1670@1|root,COG1670@2|Bacteria,1G6BV@1117|Cyanobacteria,1HP5J@1161|Nostocales	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SYD2_k127_1125176_9	1499967.BAYZ01000003_gene5884	1.568e-73	252.0	COG2454@1|root,COG2454@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	DUF434
SYD2_k127_1125176_22	1499967.BAYZ01000003_gene5884	2.856e-05	46.0	COG2454@1|root,COG2454@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	DUF434
SYD2_k127_1125176_0	886293.Sinac_4730	0.0	1060.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SYD2_k127_1191813_4	1382306.JNIM01000001_gene1598	6.921e-72	250.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SYD2_k127_1191813_9	926554.KI912650_gene4214	1.802e-11	76.0	COG0793@1|root,COG0793@2|Bacteria,1WMHU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Peptidase family S41	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SYD2_k127_1191813_8	1267533.KB906734_gene3891	9.204e-42	166.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SYD2_k127_1191813_5	192952.MM_0443	1.269e-61	218.0	COG0299@1|root,arCOG02825@2157|Archaea,2Y838@28890|Euryarchaeota,2N9JE@224756|Methanomicrobia	224756|Methanomicrobia	F	PFAM formyl transferase domain protein	-	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A2317	Formyl_trans_N
SYD2_k127_1191813_7	861299.J421_0700	2.216e-42	160.0	COG0454@1|root,COG1051@1|root,COG0456@2|Bacteria,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55,5.5.1.4	ko:K01858,ko:K03207,ko:K03574	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
SYD2_k127_1191813_1	1382359.JIAL01000001_gene1140	4.861e-126	414.0	COG0150@1|root,COG0150@2|Bacteria,3Y2GN@57723|Acidobacteria,2JITJ@204432|Acidobacteriia	204432|Acidobacteriia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SYD2_k127_1191813_6	401526.TcarDRAFT_0371	2.912e-51	196.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H1W6@909932|Negativicutes	909932|Negativicutes	S	domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Lactamase_B
SYD2_k127_1191813_3	714943.Mucpa_2860	6.209e-116	388.0	COG2252@1|root,COG2252@2|Bacteria,4NGCG@976|Bacteroidetes,1IRJ0@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Permease family	yieG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
SYD2_k127_1191813_2	1340493.JNIF01000003_gene2708	2.025e-122	402.0	COG2008@1|root,COG2008@2|Bacteria,3Y472@57723|Acidobacteria	57723|Acidobacteria	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SYD2_k127_1191813_10	926562.Oweho_2366	3.915e-08	64.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,1I47M@117743|Flavobacteriia,2PC0W@246874|Cryomorphaceae	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SYD2_k127_1191813_0	204669.Acid345_2229	8.896e-169	560.0	COG0308@1|root,COG0308@2|Bacteria,3Y7E9@57723|Acidobacteria,2JMED@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SYD2_k127_119742_4	1267535.KB906767_gene1120	4.097e-05	53.0	COG3403@1|root,COG3403@2|Bacteria	2|Bacteria	S	YqcI/YcgG family	-	-	-	ko:K09190	-	-	-	-	ko00000	-	-	-	DUF1080,YqcI_YcgG
SYD2_k127_119742_1	445972.ANACOL_03422	7.633e-108	361.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,3WGWV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SYD2_k127_119742_0	1304885.AUEY01000003_gene548	6.672e-141	472.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2MI13@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SYD2_k127_119742_3	880073.Calab_3701	6.49e-11	67.0	COG3027@1|root,COG3027@2|Bacteria,2NQ5R@2323|unclassified Bacteria	2|Bacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
SYD2_k127_119742_2	429009.Adeg_1474	1.975e-78	269.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,42EQD@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SYD2_k127_1200054_10	1267535.KB906767_gene1297	4.322e-07	59.0	COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria,2JI8N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SYD2_k127_1200054_11	313606.M23134_06009	3.186e-06	60.0	COG4399@1|root,COG4399@2|Bacteria,4NJBV@976|Bacteroidetes,47UCU@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
SYD2_k127_1200054_12	1229783.C273_09026	5.557e-06	59.0	COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,4HA30@91061|Bacilli,4GXTT@90964|Staphylococcaceae	91061|Bacilli	S	Belongs to the UPF0754 family	yheB	-	-	-	-	-	-	-	-	-	-	-	DUF445
SYD2_k127_1200054_6	886293.Sinac_1403	9.968e-33	129.0	COG1146@1|root,COG1146@2|Bacteria,2J013@203682|Planctomycetes	203682|Planctomycetes	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
SYD2_k127_1200054_9	1267535.KB906767_gene1432	5.437e-22	96.0	COG2835@1|root,COG2835@2|Bacteria,3Y8VE@57723|Acidobacteria	57723|Acidobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SYD2_k127_1200054_5	234267.Acid_2356	5.598e-38	157.0	COG0859@1|root,COG0859@2|Bacteria,3Y616@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SYD2_k127_1200054_1	330214.NIDE2553	8.79e-81	280.0	COG2870@1|root,COG2870@2|Bacteria,3J0GT@40117|Nitrospirae	40117|Nitrospirae	M	Phosphomethylpyrimidine kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
SYD2_k127_1200054_0	1070319.CAGGBEG34_190038	3.704e-91	320.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,1JZWN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	D-alanyl-d-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SYD2_k127_1200054_13	1166018.FAES_3793	3.763e-05	52.0	COG2318@1|root,COG2318@2|Bacteria,4NN7V@976|Bacteroidetes,47QXV@768503|Cytophagia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
SYD2_k127_1200054_2	477974.Daud_1604	3.134e-69	244.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,260JZ@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SYD2_k127_1200054_4	268739.Nmlp_1540	4.476e-41	168.0	COG1520@1|root,arCOG01023@1|root,arCOG01023@2157|Archaea,arCOG02492@2157|Archaea,2Y7Q0@28890|Euryarchaeota,23SYZ@183963|Halobacteria	183963|Halobacteria	M	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SYD2_k127_1200054_7	706587.Desti_4587	2.765e-26	116.0	COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,42SRU@68525|delta/epsilon subdivisions,2WPAI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	PFAM Glutamine amidotransferase class-I	guaA2	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
SYD2_k127_1200054_8	1128421.JAGA01000001_gene2128	1.299e-24	108.0	2BWQN@1|root,347D7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1200054_3	518766.Rmar_0942	7.207e-63	219.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1FJUB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SYD2_k127_1239002_4	204669.Acid345_2638	9.575e-32	127.0	COG1196@1|root,COG1196@2|Bacteria,3Y2W1@57723|Acidobacteria,2JHJF@204432|Acidobacteriia	204432|Acidobacteriia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SYD2_k127_1239002_3	29540.C481_11485	1.024e-34	142.0	COG1651@1|root,COG2116@1|root,arCOG02868@2157|Archaea,arCOG03454@2157|Archaea,2XW8R@28890|Euryarchaeota,23U3Q@183963|Halobacteria	183963|Halobacteria	OP	DSBA-like thioredoxin domain	-	-	-	ko:K21990	-	-	-	-	ko00000	1.A.16.4	-	-	Form_Nir_trans,Thioredoxin_4
SYD2_k127_1239002_0	1382306.JNIM01000001_gene1023	6.57e-307	963.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SYD2_k127_1239002_2	1382306.JNIM01000001_gene1022	9.667e-67	231.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SYD2_k127_1239002_1	760568.Desku_3262	1.528e-89	303.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,26011@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SYD2_k127_1251450_1	861299.J421_1696	5.652e-212	684.0	COG2866@1|root,COG2866@2|Bacteria,1ZUNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SYD2_k127_1251450_0	452637.Oter_4609	3.159e-270	854.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SYD2_k127_1251450_4	204669.Acid345_2015	5.133e-28	121.0	COG2006@1|root,COG2006@2|Bacteria,3Y7N1@57723|Acidobacteria,2JNKP@204432|Acidobacteriia	204432|Acidobacteriia	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SYD2_k127_1251450_3	472759.Nhal_1699	3.417e-38	152.0	COG1611@1|root,COG3350@1|root,COG1611@2|Bacteria,COG3350@2|Bacteria,1R8EU@1224|Proteobacteria,1SKDD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	YHS domain	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	YHS
SYD2_k127_1251450_2	589865.DaAHT2_0467	1.688e-81	283.0	COG0477@1|root,COG2814@2|Bacteria,1QW2F@1224|Proteobacteria,43BTU@68525|delta/epsilon subdivisions,2X74Q@28221|Deltaproteobacteria,2MKZZ@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SYD2_k127_1260257_0	945713.IALB_0635	3.082e-257	812.0	COG0178@1|root,COG0178@2|Bacteria	2|Bacteria	L	nucleotide-excision repair	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SYD2_k127_1260257_21	126957.SMAR011447-PA	6.064e-21	106.0	COG3914@1|root,KOG4626@2759|Eukaryota,38EM5@33154|Opisthokonta,3BC3N@33208|Metazoa,3CWN6@33213|Bilateria,41VJW@6656|Arthropoda	33208|Metazoa	GOT	Tetratricopeptide repeat	OGT	GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252	2.4.1.255	ko:K09667	ko00514,ko04931,map00514,map04931	-	R09304,R09676	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03036	-	GT41	-	Glyco_transf_41,TPR_1,TPR_11,TPR_2,TPR_8
SYD2_k127_1260257_24	443144.GM21_0276	3.925e-07	58.0	COG0457@1|root,COG0457@2|Bacteria	443144.GM21_0276|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1260257_25	8090.ENSORLP00000007935	3.515e-05	52.0	COG0457@1|root,COG3914@1|root,KOG1124@2759|Eukaryota,KOG4626@2759|Eukaryota,38EM5@33154|Opisthokonta,3BC3N@33208|Metazoa,3CWN6@33213|Bilateria,4870C@7711|Chordata,48X60@7742|Vertebrata,49R5B@7898|Actinopterygii	33208|Metazoa	GOT	O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1	OGT	GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252	2.4.1.255	ko:K09667	ko00514,ko04931,map00514,map04931	-	R09304,R09676	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03036	-	GT41	-	Glyco_transf_41,TPR_1,TPR_11,TPR_2,TPR_8
SYD2_k127_1260257_12	518766.Rmar_1330	4.448e-65	240.0	COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes	976|Bacteroidetes	KLT	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,Big_2,FGE-sulfatase
SYD2_k127_1260257_16	671143.DAMO_1988	8.209e-37	159.0	COG1262@1|root,COG1262@2|Bacteria,2NR8C@2323|unclassified Bacteria	2|Bacteria	S	Sulfatase-modifying factor enzyme 1	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase
SYD2_k127_1260257_8	383372.Rcas_2288	4.147e-86	309.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SYD2_k127_1260257_19	1499967.BAYZ01000073_gene2011	1.818e-30	125.0	COG1610@1|root,COG1610@2|Bacteria,2NPQ9@2323|unclassified Bacteria	2|Bacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SYD2_k127_1260257_17	243231.GSU1585	8.668e-35	141.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2WQYV@28221|Deltaproteobacteria,43V1S@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SYD2_k127_1260257_6	234267.Acid_5180	3.207e-116	395.0	COG0195@1|root,COG0195@2|Bacteria,3Y379@57723|Acidobacteria	57723|Acidobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
SYD2_k127_1260257_3	1382359.JIAL01000001_gene1877	8.669e-219	708.0	COG0532@1|root,COG0532@2|Bacteria,3Y3UG@57723|Acidobacteria,2JHXH@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
SYD2_k127_1260257_23	608534.GCWU000341_02175	5.943e-12	71.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,2PSF3@265975|Oribacterium	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SYD2_k127_1260257_10	204669.Acid345_4214	1.715e-78	274.0	COG0618@1|root,COG0618@2|Bacteria,3Y2GZ@57723|Acidobacteria,2JI0W@204432|Acidobacteriia	204432|Acidobacteriia	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SYD2_k127_1260257_20	297246.lpp0851	3.896e-27	117.0	COG1943@1|root,COG1943@2|Bacteria,1QC63@1224|Proteobacteria,1T7V3@1236|Gammaproteobacteria,1JFWA@118969|Legionellales	118969|Legionellales	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SYD2_k127_1260257_13	485913.Krac_2076	3.678e-53	194.0	COG2109@1|root,COG2109@2|Bacteria,2G6Q6@200795|Chloroflexi	200795|Chloroflexi	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
SYD2_k127_1260257_2	204669.Acid345_2969	3.755e-244	779.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,3Y3GW@57723|Acidobacteria,2JHKK@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
SYD2_k127_1260257_18	240015.ACP_0219	3.62e-31	138.0	COG0457@1|root,COG0457@2|Bacteria,3Y3JH@57723|Acidobacteria,2JI8K@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SYD2_k127_1260257_7	1340493.JNIF01000003_gene1295	4.238e-101	337.0	COG0777@1|root,COG0777@2|Bacteria,3Y2U9@57723|Acidobacteria	57723|Acidobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SYD2_k127_1260257_9	671143.DAMO_1989	7.624e-84	294.0	COG0285@1|root,COG0285@2|Bacteria,2NP60@2323|unclassified Bacteria	2|Bacteria	H	Belongs to the folylpolyglutamate synthase family	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0166,iSB619.SA_RS08370	Mur_ligase_C,Mur_ligase_M
SYD2_k127_1260257_15	1219084.AP014508_gene1055	3.008e-37	147.0	COG0494@1|root,COG0494@2|Bacteria,2GD2W@200918|Thermotogae	200918|Thermotogae	L	pfam nudix	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SYD2_k127_1260257_4	443143.GM18_2000	1.862e-157	508.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,42PC8@68525|delta/epsilon subdivisions,2X5FY@28221|Deltaproteobacteria,43W2E@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SYD2_k127_1260257_22	237368.SCABRO_01702	4.794e-16	86.0	COG0792@1|root,COG0792@2|Bacteria,2J0GX@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SYD2_k127_1260257_11	1340493.JNIF01000004_gene275	2.186e-76	280.0	COG0515@1|root,COG0515@2|Bacteria	1340493.JNIF01000004_gene275|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1260257_14	251221.35211166	7.74e-52	208.0	COG3191@1|root,COG3191@2|Bacteria	2|Bacteria	EQ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
SYD2_k127_1260257_1	234267.Acid_2017	7.99e-254	807.0	COG1506@1|root,COG1506@2|Bacteria,3Y2HK@57723|Acidobacteria	57723|Acidobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SYD2_k127_1260257_5	99598.Cal7507_5295	5.865e-127	416.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1G1R7@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
SYD2_k127_1276149_4	204669.Acid345_2602	5.179e-30	130.0	COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria	57723|Acidobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
SYD2_k127_1276149_5	404380.Gbem_2323	3.572e-08	64.0	COG3005@1|root,COG3005@2|Bacteria,1NJY9@1224|Proteobacteria,42XJ4@68525|delta/epsilon subdivisions,2WSQ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	12 heme-binding sites	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
SYD2_k127_1276149_2	234267.Acid_4206	1.288e-119	404.0	COG4191@1|root,COG4191@2|Bacteria,3Y42C@57723|Acidobacteria	57723|Acidobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SYD2_k127_1276149_1	234267.Acid_4207	1.388e-158	512.0	COG2204@1|root,COG2204@2|Bacteria,3Y3T2@57723|Acidobacteria	57723|Acidobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SYD2_k127_1276149_3	204669.Acid345_2605	1.649e-38	151.0	COG1913@1|root,COG1913@2|Bacteria,3Y880@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase family M54	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
SYD2_k127_1276149_6	289376.THEYE_A1056	1.349e-06	57.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7,PKD
SYD2_k127_1276149_7	204669.Acid345_3829	0.0001808	48.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1276149_0	204669.Acid345_2713	3.949e-175	569.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	57723|Acidobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
SYD2_k127_1296045_13	240015.ACP_2983	6.664e-12	68.0	COG0653@1|root,COG0653@2|Bacteria,3Y34P@57723|Acidobacteria,2JHSP@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SYD2_k127_1296045_2	204669.Acid345_2491	1.411e-121	405.0	COG0527@1|root,COG0527@2|Bacteria,3Y34W@57723|Acidobacteria,2JHV2@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
SYD2_k127_1296045_6	1382359.JIAL01000001_gene2279	1.014e-95	324.0	COG0624@1|root,COG0624@2|Bacteria,3Y2K0@57723|Acidobacteria,2JIEY@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM peptidase	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SYD2_k127_1296045_8	234267.Acid_6981	1.347e-55	202.0	COG0289@1|root,COG0289@2|Bacteria,3Y50R@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the DapB family	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SYD2_k127_1296045_5	204669.Acid345_2493	7.542e-97	325.0	COG0329@1|root,COG0329@2|Bacteria,3Y3V8@57723|Acidobacteria,2JICI@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SYD2_k127_1296045_4	204669.Acid345_2087	6.418e-116	379.0	COG2171@1|root,COG2171@2|Bacteria,3Y2Z3@57723|Acidobacteria,2JIDV@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the transferase hexapeptide repeat family	-	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep_2,THDPS_N_2
SYD2_k127_1296045_14	994479.GL877881_gene6384	8.235e-05	46.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	PT-HINT,VWA_2
SYD2_k127_1296045_12	1121403.AUCV01000019_gene3316	6.73e-23	101.0	28ZBQ@1|root,2ZM3I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1296045_7	1227487.C474_21431	4.714e-66	240.0	COG0436@1|root,arCOG01130@2157|Archaea,2XSVT@28890|Euryarchaeota,23SDZ@183963|Halobacteria	183963|Halobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SYD2_k127_1296045_3	309801.trd_0366	3.517e-116	384.0	COG0136@1|root,COG0136@2|Bacteria,2G5T9@200795|Chloroflexi,27XNM@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SYD2_k127_1296045_9	1267533.KB906737_gene1567	6.022e-51	188.0	COG2945@1|root,COG2945@2|Bacteria,3Y35I@57723|Acidobacteria,2JIVZ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SYD2_k127_1296045_0	56110.Oscil6304_3204	9.942e-138	475.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
SYD2_k127_1296045_10	292415.Tbd_0663	1.964e-43	163.0	COG1285@1|root,COG1285@2|Bacteria,1RH5E@1224|Proteobacteria,2VT66@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM MgtC SapB transporter	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
SYD2_k127_1296045_1	1047013.AQSP01000133_gene2112	3.522e-137	458.0	COG1022@1|root,COG1022@2|Bacteria,2NNTM@2323|unclassified Bacteria	2|Bacteria	I	COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming)	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SYD2_k127_1296045_11	671143.DAMO_2346	9.563e-42	172.0	COG0484@1|root,COG3307@1|root,COG0484@2|Bacteria,COG3307@2|Bacteria,2NPHS@2323|unclassified Bacteria	2|Bacteria	M	O-Antigen ligase	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	DnaJ,Wzy_C
SYD2_k127_1334447_2	204669.Acid345_3333	2.796e-193	614.0	COG0531@1|root,COG0531@2|Bacteria,3Y3Z8@57723|Acidobacteria,2JHZI@204432|Acidobacteriia	204432|Acidobacteriia	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SYD2_k127_1334447_8	1329516.JPST01000003_gene1165	1.158e-100	359.0	COG2120@1|root,COG2120@2|Bacteria,1UYPV@1239|Firmicutes,4HCT3@91061|Bacilli,27CPN@186824|Thermoactinomycetaceae	91061|Bacilli	Q	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc,PIG-L
SYD2_k127_1334447_7	398767.Glov_3597	2.98e-117	412.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria,43T20@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
SYD2_k127_1334447_1	1131269.AQVV01000005_gene331	1.985e-212	668.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SYD2_k127_1334447_0	1123242.JH636434_gene3359	1.199e-236	747.0	COG1166@1|root,COG1166@2|Bacteria,2IX6P@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
SYD2_k127_1334447_10	1379698.RBG1_1C00001G0709	8.1e-80	278.0	COG1899@1|root,COG1899@2|Bacteria,2NR8I@2323|unclassified Bacteria	2|Bacteria	O	Deoxyhypusine synthase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
SYD2_k127_1334447_11	1250232.JQNJ01000001_gene3833	1.479e-74	260.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,1HYIB@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SYD2_k127_1334447_19	240015.ACP_0219	3.497e-36	153.0	COG0457@1|root,COG0457@2|Bacteria,3Y3JH@57723|Acidobacteria,2JI8K@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SYD2_k127_1334447_4	1128421.JAGA01000003_gene2811	4.047e-154	495.0	COG0498@1|root,COG0498@2|Bacteria,2NP42@2323|unclassified Bacteria	2|Bacteria	E	Threonine synthase	MA20_41710	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SYD2_k127_1334447_17	321332.CYB_1473	5.676e-49	179.0	COG0652@1|root,COG0652@2|Bacteria,1G5BD@1117|Cyanobacteria,1H0AB@1129|Synechococcus	1117|Cyanobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	rot	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SYD2_k127_1334447_18	1410625.JHWK01000002_gene123	8.49e-47	179.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,27JR0@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
SYD2_k127_1334447_22	204669.Acid345_4410	1.196e-31	133.0	COG0352@1|root,COG0352@2|Bacteria,3Y53Y@57723|Acidobacteria,2JJTS@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SYD2_k127_1334447_16	204669.Acid345_4380	1.435e-54	216.0	COG0457@1|root,COG2956@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,3Y89N@57723|Acidobacteria	57723|Acidobacteria	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
SYD2_k127_1334447_15	216591.BCAL3131	8.431e-58	211.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,2VHT7@28216|Betaproteobacteria,1K0NU@119060|Burkholderiaceae	28216|Betaproteobacteria	GM	Transport permease protein	tagG	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SYD2_k127_1334447_14	986075.CathTA2_1634	4.929e-59	222.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli	91061|Bacilli	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SYD2_k127_1334447_3	886293.Sinac_1825	2.533e-179	571.0	COG2256@1|root,COG2256@2|Bacteria,2IX8G@203682|Planctomycetes	203682|Planctomycetes	L	ATPase related to the helicase subunit of the Holliday junction resolvase	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SYD2_k127_1334447_29	525904.Tter_0503	6.3e-05	54.0	COG0500@1|root,COG2226@2|Bacteria,2NPGE@2323|unclassified Bacteria	2|Bacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SYD2_k127_1334447_30	28042.GU90_06730	0.0005734	46.0	COG1826@1|root,COG1826@2|Bacteria,2GQQX@201174|Actinobacteria,4E7RK@85010|Pseudonocardiales	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SYD2_k127_1334447_13	204669.Acid345_4201	2.475e-66	231.0	COG1403@1|root,COG1403@2|Bacteria,3Y3PW@57723|Acidobacteria,2JI65@204432|Acidobacteriia	204432|Acidobacteriia	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SYD2_k127_1334447_5	264462.Bd3480	6.226e-151	482.0	COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,42P6R@68525|delta/epsilon subdivisions,2MSMN@213481|Bdellovibrionales,2WKXS@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SYD2_k127_1334447_24	370438.PTH_2756	2.596e-28	123.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,2627P@186807|Peptococcaceae	186801|Clostridia	F	PFAM Phosphoribosyltransferase	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
SYD2_k127_1334447_26	204669.Acid345_4135	1.037e-27	116.0	COG1734@1|root,COG1734@2|Bacteria,3Y5PJ@57723|Acidobacteria,2JK2N@204432|Acidobacteriia	204432|Acidobacteriia	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SYD2_k127_1334447_27	203123.OEOE_0108	3.513e-27	117.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli,4AXRA@81850|Leuconostocaceae	91061|Bacilli	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
SYD2_k127_1334447_9	204669.Acid345_0023	1.326e-85	293.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria,2JICQ@204432|Acidobacteriia	57723|Acidobacteria	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
SYD2_k127_1334447_23	1267535.KB906767_gene3549	2.78e-31	128.0	COG0799@1|root,COG0799@2|Bacteria,3Y5SD@57723|Acidobacteria	57723|Acidobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SYD2_k127_1334447_20	671143.DAMO_0333	4.675e-36	145.0	COG1057@1|root,COG1057@2|Bacteria,2NPJU@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18,3.6.1.55	ko:K00969,ko:K03574	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	CTP_transf_like
SYD2_k127_1334447_6	234267.Acid_3160	4.496e-120	395.0	COG0536@1|root,COG0536@2|Bacteria,3Y2J7@57723|Acidobacteria	57723|Acidobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
SYD2_k127_1334447_21	56110.Oscil6304_0246	5.967e-35	135.0	COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria,1HCCX@1150|Oscillatoriales	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SYD2_k127_1334447_25	861299.J421_3337	3.713e-28	116.0	COG0261@1|root,COG0261@2|Bacteria,1ZTS8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SYD2_k127_1334447_12	1123502.AQXD01000001_gene656	2.635e-69	239.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1X43Q@135614|Xanthomonadales	135614|Xanthomonadales	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SYD2_k127_1342379_0	1304878.AUGD01000026_gene3934	1.866e-76	263.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,2UDFZ@28211|Alphaproteobacteria,3K5YJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Cytidylyltransferase	-	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
SYD2_k127_1342379_1	1320556.AVBP01000022_gene2119	2.148e-37	154.0	COG0673@1|root,COG0673@2|Bacteria,1Q8R1@1224|Proteobacteria,2U8HN@28211|Alphaproteobacteria,43P8T@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SYD2_k127_1342379_2	742735.HMPREF9467_04122	2.508e-15	85.0	COG0673@1|root,COG0673@2|Bacteria,1UZRV@1239|Firmicutes,24CIU@186801|Clostridia,2227S@1506553|Lachnoclostridium	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	ko:K03810	-	-	-	-	ko00000	-	-	-	GFO_IDH_MocA
SYD2_k127_1344750_1	1254432.SCE1572_23655	1.198e-58	222.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YWMB@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SYD2_k127_1344750_0	321332.CYB_0632	1.101e-217	692.0	COG0058@1|root,COG0058@2|Bacteria,1G1HB@1117|Cyanobacteria,1H46Q@1129|Synechococcus	1117|Cyanobacteria	G	phosphorylase	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SYD2_k127_1345676_14	1128421.JAGA01000002_gene1985	1.094e-46	185.0	COG0823@1|root,COG4995@1|root,COG0823@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CHAT,PD40,WD40
SYD2_k127_1345676_28	1463881.KL591006_gene2248	1.05e-06	61.0	2ECD7@1|root,336BF@2|Bacteria,2IH9P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1345676_23	1038859.AXAU01000001_gene2613	7.132e-13	74.0	2AKTJ@1|root,31BKK@2|Bacteria,1NYB1@1224|Proteobacteria,2UTN8@28211|Alphaproteobacteria,3K4H7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1345676_27	323261.Noc_1987	9.947e-08	64.0	COG0457@1|root,COG5010@1|root,COG0457@2|Bacteria,COG5010@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria,1WX0E@135613|Chromatiales	135613|Chromatiales	U	PEP-CTERM system TPR-repeat lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_4,TPR_8
SYD2_k127_1345676_12	886293.Sinac_3180	1.949e-50	195.0	COG0671@1|root,COG0671@2|Bacteria,2J3BG@203682|Planctomycetes	203682|Planctomycetes	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1345676_0	1382359.JIAL01000001_gene2381	1.692e-187	607.0	COG0322@1|root,COG0322@2|Bacteria,3Y2Y7@57723|Acidobacteria,2JI6E@204432|Acidobacteriia	204432|Acidobacteriia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
SYD2_k127_1345676_7	1340493.JNIF01000003_gene2102	6.492e-69	245.0	COG0524@1|root,COG0524@2|Bacteria,3Y659@57723|Acidobacteria	57723|Acidobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.184	ko:K18478	-	-	R10970	RC00002,RC00017	ko00000,ko01000	-	-	-	PfkB
SYD2_k127_1345676_5	1123355.JHYO01000013_gene1144	6.092e-85	297.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2TUEW@28211|Alphaproteobacteria,36Y2U@31993|Methylocystaceae	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,MFS_2,Sugar_tr
SYD2_k127_1345676_1	118163.Ple7327_0557	8.416e-154	506.0	COG3975@1|root,COG3975@2|Bacteria,1G0YP@1117|Cyanobacteria,3VHK8@52604|Pleurocapsales	1117|Cyanobacteria	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
SYD2_k127_1345676_16	292.DM42_5631	4.991e-42	167.0	COG0627@1|root,COG0627@2|Bacteria,1N3VN@1224|Proteobacteria,2WGE4@28216|Betaproteobacteria,1K04T@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SYD2_k127_1345676_26	438753.AZC_2217	2.488e-11	66.0	2CA82@1|root,2ZP0Q@2|Bacteria,1NDH6@1224|Proteobacteria,2UHN1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF3658
SYD2_k127_1345676_13	861299.J421_6341	2.981e-47	172.0	COG1917@1|root,COG1917@2|Bacteria,1ZTY8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SYD2_k127_1345676_25	926566.Terro_2880	9.745e-12	74.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,3Y8DM@57723|Acidobacteria	57723|Acidobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1345676_15	485913.Krac_5622	4.389e-45	164.0	COG5207@1|root,COG5207@2|Bacteria	2|Bacteria	O	Pfam Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N,zf-UBP
SYD2_k127_1345676_18	1403313.AXBR01000008_gene621	5.03e-33	141.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,1ZBST@1386|Bacillus	91061|Bacilli	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SYD2_k127_1345676_21	1198114.AciX9_2681	7.055e-17	88.0	COG2980@1|root,COG2980@2|Bacteria,3Y4V4@57723|Acidobacteria,2JJKB@204432|Acidobacteriia	204432|Acidobacteriia	M	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
SYD2_k127_1345676_17	1122915.AUGY01000084_gene6195	3.337e-37	144.0	COG0346@1|root,COG0346@2|Bacteria,1VCGT@1239|Firmicutes,4HKDV@91061|Bacilli,26ZEW@186822|Paenibacillaceae	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SYD2_k127_1345676_24	1267535.KB906767_gene105	1.312e-12	81.0	COG3307@1|root,COG3307@2|Bacteria,3Y67G@57723|Acidobacteria	57723|Acidobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SYD2_k127_1345676_9	234267.Acid_3348	1.959e-57	218.0	COG0624@1|root,COG0624@2|Bacteria,3Y2XS@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SYD2_k127_1345676_11	671143.DAMO_2071	2.688e-53	196.0	COG2357@1|root,COG2357@2|Bacteria	2|Bacteria	S	guanosine tetraphosphate metabolic process	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	DUF429,RelA_SpoT
SYD2_k127_1345676_22	278963.ATWD01000002_gene765	5.664e-16	90.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SYD2_k127_1345676_4	697281.Mahau_1700	3.278e-106	354.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,42EZE@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Phosphate acetyl butaryl transferase	pta	GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
SYD2_k127_1345676_19	1123371.ATXH01000022_gene961	1.082e-20	99.0	COG3339@1|root,COG3339@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SYD2_k127_1345676_3	234267.Acid_3614	1.127e-135	441.0	COG1060@1|root,COG1060@2|Bacteria,3Y2IA@57723|Acidobacteria	57723|Acidobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SYD2_k127_1345676_6	479434.Sthe_0108	7.517e-76	265.0	COG2159@1|root,COG2159@2|Bacteria,2G8UX@200795|Chloroflexi,27Z57@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
SYD2_k127_1345676_10	443144.GM21_0993	8.8e-55	199.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,42S4S@68525|delta/epsilon subdivisions,2WNIV@28221|Deltaproteobacteria,43S1H@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	cytidylate kinase activity	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SYD2_k127_1345676_8	457425.XNR_5406	3.361e-59	211.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria	201174|Actinobacteria	H	riboflavin synthase, alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SYD2_k127_1345676_2	398767.Glov_0881	6.533e-139	454.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SYD2_k127_1345676_29	1112217.PPL19_07106	0.0004955	53.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Protein involved in outer membrane biogenesis	asmA	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA
SYD2_k127_1364311_2	1396141.BATP01000003_gene4881	1.453e-39	156.0	COG3568@1|root,COG3568@2|Bacteria,46X7C@74201|Verrucomicrobia,2IUUK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SYD2_k127_1364311_5	1267533.KB906735_gene4559	1.947e-21	95.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria,2JJXU@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
SYD2_k127_1364311_0	1499967.BAYZ01000182_gene4414	7.534e-269	843.0	COG0021@1|root,COG0021@2|Bacteria,2NS3T@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SYD2_k127_1364311_1	266117.Rxyl_1675	1.005e-117	397.0	COG1070@1|root,COG1070@2|Bacteria,2IAKI@201174|Actinobacteria,4CU2I@84995|Rubrobacteria	84995|Rubrobacteria	G	Belongs to the FGGY kinase family	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SYD2_k127_1364311_4	469383.Cwoe_1850	4.27e-24	106.0	COG1310@1|root,COG1310@2|Bacteria,2IFB5@201174|Actinobacteria,4CQGR@84995|Rubrobacteria	84995|Rubrobacteria	S	JAB/MPN domain	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SYD2_k127_1364311_3	545696.HOLDEFILI_01549	9.311e-29	117.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,3VNWM@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SYD2_k127_1365855_0	324602.Caur_2261	3.431e-111	365.0	COG0444@1|root,COG0444@2|Bacteria,2G61B@200795|Chloroflexi,374U3@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SYD2_k127_1365855_3	338963.Pcar_1793	9.893e-42	159.0	2B1XW@1|root,31UE7@2|Bacteria,1NXJ5@1224|Proteobacteria	1224|Proteobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SYD2_k127_1365855_1	1183438.GKIL_1123	4.803e-104	349.0	COG1173@1|root,COG1173@2|Bacteria,1G0CD@1117|Cyanobacteria	1117|Cyanobacteria	P	'ABC-type dipeptide oligopeptide nickel transport	appC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SYD2_k127_1365855_2	251221.35214699	2.817e-97	326.0	COG0601@1|root,COG0601@2|Bacteria,1G01A@1117|Cyanobacteria	1117|Cyanobacteria	EP	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033,ko:K15581,ko:K15585	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
SYD2_k127_1365855_4	234267.Acid_4781	2.245e-08	57.0	COG0237@1|root,COG0237@2|Bacteria,3Y4R2@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
SYD2_k127_1451073_6	987059.RBXJA2T_06485	8.16e-10	72.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181	ko:K00568,ko:K18827	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781,R10657,R10658	RC00002,RC00003,RC00078,RC00392,RC01895,RC03220	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SYD2_k127_1451073_2	1174528.JH992898_gene3096	5.858e-63	237.0	COG4372@1|root,COG4976@1|root,COG4372@2|Bacteria,COG4976@2|Bacteria,1GR2W@1117|Cyanobacteria	1117|Cyanobacteria	N	Methionine biosynthesis protein MetW	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	Methyltransf_11,Methyltransf_23
SYD2_k127_1451073_0	555793.WSK_4263	3.975e-119	392.0	COG0438@1|root,COG0438@2|Bacteria,1NF7D@1224|Proteobacteria,2U52N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Methyltransf_11
SYD2_k127_1451073_1	373994.Riv7116_5912	8.144e-95	325.0	COG0438@1|root,COG0438@2|Bacteria,1G3BR@1117|Cyanobacteria,1HRMQ@1161|Nostocales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SYD2_k127_1451073_4	1248916.ANFY01000004_gene1680	6.218e-22	112.0	COG2931@1|root,COG2931@2|Bacteria,1RD10@1224|Proteobacteria,2U9TE@28211|Alphaproteobacteria,2K1W4@204457|Sphingomonadales	204457|Sphingomonadales	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
SYD2_k127_1451073_5	1229780.BN381_80249	1.755e-20	107.0	COG1404@1|root,COG4447@1|root,COG5549@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	B_lectin,Flg_new,PKD,SLH
SYD2_k127_1452271_1	1297865.APJD01000003_gene6376	1.302e-73	250.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2TTUR@28211|Alphaproteobacteria,3JTPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
SYD2_k127_1452271_2	1297863.APJF01000022_gene4475	1.767e-53	194.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2U9JM@28211|Alphaproteobacteria,3JY59@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	ApaG domain	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
SYD2_k127_1452271_0	709797.CSIRO_1263	1.318e-149	479.0	COG4645@1|root,COG4645@2|Bacteria,1PI9Q@1224|Proteobacteria,2U1C7@28211|Alphaproteobacteria,3JQY7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	OpgC protein	MA20_22360	-	-	-	-	-	-	-	-	-	-	-	OpgC_C
SYD2_k127_15110_2	1210884.HG799468_gene13789	8.178e-55	200.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SYD2_k127_15110_0	1379698.RBG1_1C00001G0558	5.974e-120	398.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Calx-beta,FG-GAP,VCBS
SYD2_k127_15110_4	204669.Acid345_4293	8.981e-13	78.0	COG2823@1|root,COG2823@2|Bacteria,3Y99E@57723|Acidobacteria,2JP08@204432|Acidobacteriia	204432|Acidobacteriia	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_15110_1	1121920.AUAU01000016_gene1317	1.249e-64	227.0	COG0377@1|root,COG0377@2|Bacteria,3Y3JS@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SYD2_k127_15110_3	1162668.LFE_1700	1.463e-31	128.0	COG0838@1|root,COG0838@2|Bacteria,3J0MS@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SYD2_k127_1609688_0	234267.Acid_0759	0.0	1050.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2920,Peptidase_S9
SYD2_k127_1609688_7	204669.Acid345_4517	5.183e-50	194.0	COG1463@1|root,COG1463@2|Bacteria,3Y3SX@57723|Acidobacteria,2JIP6@204432|Acidobacteriia	204432|Acidobacteriia	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SYD2_k127_1609688_6	401053.AciPR4_1852	6.488e-68	252.0	COG1127@1|root,COG1127@2|Bacteria,3Y3YI@57723|Acidobacteria,2JIF1@204432|Acidobacteriia	204432|Acidobacteriia	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SYD2_k127_1609688_5	1382359.JIAL01000001_gene2412	3.211e-70	245.0	COG0767@1|root,COG0767@2|Bacteria,3Y43S@57723|Acidobacteria,2JI8E@204432|Acidobacteriia	204432|Acidobacteriia	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SYD2_k127_1609688_8	1198114.AciX9_1272	7.868e-32	132.0	COG1595@1|root,COG1595@2|Bacteria,3Y4CA@57723|Acidobacteria,2JJ0Z@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SYD2_k127_1609688_4	204669.Acid345_3335	3.703e-99	347.0	COG2206@1|root,COG5000@1|root,COG2206@2|Bacteria,COG5000@2|Bacteria,3Y7I5@57723|Acidobacteria,2JMTE@204432|Acidobacteriia	204432|Acidobacteriia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
SYD2_k127_1609688_3	1267535.KB906767_gene4183	8.432e-101	341.0	COG0552@1|root,COG0552@2|Bacteria,3Y3JQ@57723|Acidobacteria,2JIXJ@204432|Acidobacteriia	204432|Acidobacteriia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SYD2_k127_1609688_9	240015.ACP_3265	6.066e-26	116.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	irrE	-	-	ko:K21686	-	-	-	-	ko00000,ko03000	-	-	-	DUF4344,Peptidase_M78
SYD2_k127_1609688_2	1379698.RBG1_1C00001G1345	1.97e-103	351.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria	2|Bacteria	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c_2,SSF,SpoIIE
SYD2_k127_1609688_1	204669.Acid345_0689	1.273e-147	477.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SYD2_k127_1609688_10	1382359.JIAL01000001_gene2547	1.595e-20	106.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria,2JHV1@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
SYD2_k127_1609688_11	1267533.KB906736_gene1223	5.551e-12	77.0	COG3712@1|root,COG3712@2|Bacteria,3Y5MB@57723|Acidobacteria,2JJYX@204432|Acidobacteriia	204432|Acidobacteriia	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SYD2_k127_1609688_12	1463853.JOHW01000025_gene2793	0.0002224	46.0	COG1725@1|root,COG1725@2|Bacteria,2IHTD@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SYD2_k127_1650891_0	123214.PERMA_0029	1.636e-202	643.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2G3NT@200783|Aquificae	200783|Aquificae	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SYD2_k127_1650891_6	1089550.ATTH01000001_gene1014	3.002e-32	139.0	COG0699@1|root,COG1520@1|root,COG0699@2|Bacteria,COG1520@2|Bacteria,4PHXE@976|Bacteroidetes,1FKAD@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1650891_4	234267.Acid_1718	1.487e-48	184.0	COG1183@1|root,COG1183@2|Bacteria,3Y3I7@57723|Acidobacteria	57723|Acidobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
SYD2_k127_1650891_3	204669.Acid345_2360	1.378e-50	189.0	COG0688@1|root,COG0688@2|Bacteria,3Y4AZ@57723|Acidobacteria,2JJ6I@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
SYD2_k127_1650891_9	234267.Acid_0472	9.502e-09	60.0	2ETRB@1|root,33M8W@2|Bacteria,3Y5ZS@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
SYD2_k127_1650891_7	986075.CathTA2_1482	8.403e-23	104.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli	91061|Bacilli	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SYD2_k127_1650891_8	546271.Selsp_0550	7.8e-20	99.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4H47Z@909932|Negativicutes	909932|Negativicutes	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SYD2_k127_1650891_2	370438.PTH_1386	1.052e-108	362.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,2607Y@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA2	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SYD2_k127_1650891_5	314278.NB231_02448	7.806e-36	152.0	COG4424@1|root,COG4424@2|Bacteria,1QVF4@1224|Proteobacteria,1S5MJ@1236|Gammaproteobacteria,1WZ97@135613|Chromatiales	135613|Chromatiales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SYD2_k127_1650891_1	234267.Acid_4760	8.331e-141	465.0	COG0249@1|root,COG0249@2|Bacteria,3Y2J5@57723|Acidobacteria	57723|Acidobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SYD2_k127_1654951_2	234267.Acid_7065	2.565e-23	107.0	28M67@1|root,31CRD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1654951_1	439235.Dalk_1975	1.664e-34	144.0	COG2267@1|root,COG2267@2|Bacteria,1P3EB@1224|Proteobacteria,42UGM@68525|delta/epsilon subdivisions,2WQR2@28221|Deltaproteobacteria,2MPGU@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SYD2_k127_1654951_0	574375.BAGA_00445	2.226e-64	234.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,1ZBKE@1386|Bacillus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177,ko:K03483	-	-	-	-	ko00000,ko01000,ko03000,ko03016	-	-	iSB619.SA_RS06305	TruB-C_2,TruB_C_2,TruB_N
SYD2_k127_1654951_3	926550.CLDAP_16260	4.589e-09	64.0	COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi	200795|Chloroflexi	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SYD2_k127_1666566_3	332101.JIBU02000023_gene4702	4.493e-77	268.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,36DG5@31979|Clostridiaceae	186801|Clostridia	I	Dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SYD2_k127_1666566_2	1121468.AUBR01000026_gene2914	9.335e-78	267.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,42EVN@68295|Thermoanaerobacterales	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SYD2_k127_1666566_1	485913.Krac_12069	9.412e-113	372.0	COG0604@1|root,COG0604@2|Bacteria,2G7Z0@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SYD2_k127_1666566_4	234267.Acid_5931	3.054e-72	254.0	COG0730@1|root,COG0730@2|Bacteria,3Y4IM@57723|Acidobacteria	57723|Acidobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SYD2_k127_1666566_5	1218103.CIN01S_10_02310	2.599e-58	210.0	COG2094@1|root,COG2094@2|Bacteria,4NP22@976|Bacteroidetes,1I1TP@117743|Flavobacteriia,3ZQNN@59732|Chryseobacterium	976|Bacteroidetes	L	Belongs to the DNA glycosylase MPG family	mpg	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SYD2_k127_1666566_10	682795.AciX8_4747	3.572e-20	96.0	2FCE6@1|root,344HQ@2|Bacteria,3Y8DK@57723|Acidobacteria,2JNHY@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1666566_6	1242864.D187_008155	2.114e-48	199.0	COG0768@1|root,COG2385@1|root,COG0768@2|Bacteria,COG2385@2|Bacteria,1RGJS@1224|Proteobacteria,42RZE@68525|delta/epsilon subdivisions,2WNH8@28221|Deltaproteobacteria	1224|Proteobacteria	D	Stage II sporulation D domain protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID,TPR_6,TPR_8
SYD2_k127_1666566_9	316067.Geob_3182	1.154e-38	152.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,42VJU@68525|delta/epsilon subdivisions,2WRA4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
SYD2_k127_1666566_0	204669.Acid345_0928	1.076e-301	984.0	COG2373@1|root,COG2373@2|Bacteria,3Y439@57723|Acidobacteria,2JMCS@204432|Acidobacteriia	204432|Acidobacteriia	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
SYD2_k127_1666566_8	204669.Acid345_0927	3.593e-47	180.0	COG3234@1|root,COG3234@2|Bacteria,3Y4K7@57723|Acidobacteria,2JMR9@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1175)	-	-	-	ko:K09934	-	-	-	-	ko00000	-	-	-	DUF1175
SYD2_k127_1666566_7	1254432.SCE1572_26205	2.173e-47	195.0	COG0437@1|root,COG0664@1|root,COG0437@2|Bacteria,COG0664@2|Bacteria,1QZTQ@1224|Proteobacteria,43CNM@68525|delta/epsilon subdivisions,2X2C7@28221|Deltaproteobacteria,2YX3F@29|Myxococcales	28221|Deltaproteobacteria	CT	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,cNMP_binding
SYD2_k127_1666566_12	130081.XP_005704957.1	0.0007949	52.0	KOG1881@1|root,KOG1881@2759|Eukaryota	2759|Eukaryota	A	Solute carrier family 4 (anion exchanger), member 1, adaptor protein	SLC4A1AP	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005886,GO:0016020,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0070013,GO:0071944,GO:0097159,GO:1901363	-	ko:K06091,ko:K08956	ko04390,ko04391,ko04530,ko05165,map04390,map04391,map04530,map05165	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	FHA,dsrm
SYD2_k127_1666566_11	313628.LNTAR_04906	0.0005325	51.0	COG0457@1|root,COG0457@2|Bacteria	313628.LNTAR_04906|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1713951_0	247490.KSU1_C1626	1.039e-203	649.0	COG1966@1|root,COG1966@2|Bacteria,2IWZE@203682|Planctomycetes	203682|Planctomycetes	T	Carbon starvation protein	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
SYD2_k127_1713951_2	926567.TheveDRAFT_0701	9.999e-27	125.0	COG0501@1|root,COG0501@2|Bacteria,3TCJJ@508458|Synergistetes	508458|Synergistetes	M	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SYD2_k127_1713951_1	1267533.KB906741_gene405	1.099e-74	254.0	COG4638@1|root,COG4638@2|Bacteria,3Y547@57723|Acidobacteria,2JNCI@204432|Acidobacteriia	204432|Acidobacteriia	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
SYD2_k127_1725732_0	1382359.JIAL01000001_gene901	9.523e-272	861.0	COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria,2JIHQ@204432|Acidobacteriia	204432|Acidobacteriia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SYD2_k127_1753640_9	525373.HMPREF0766_12342	6.635e-09	61.0	COG0346@1|root,COG0346@2|Bacteria,4NWUX@976|Bacteroidetes,1IZPJ@117747|Sphingobacteriia	976|Bacteroidetes	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SYD2_k127_1753640_5	937777.Deipe_2737	7.993e-35	136.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SYD2_k127_1753640_3	555779.Dthio_PD3181	1.777e-45	174.0	2CC7H@1|root,32RJ0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1753640_7	1121921.KB898706_gene3013	2.024e-19	100.0	COG0417@1|root,COG0417@2|Bacteria,1QVMG@1224|Proteobacteria,1T2EP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
SYD2_k127_1753640_6	234267.Acid_2675	1.346e-30	127.0	COG1943@1|root,COG1943@2|Bacteria,3Y8QI@57723|Acidobacteria	57723|Acidobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SYD2_k127_1753640_1	945713.IALB_2867	1.149e-103	353.0	COG1322@1|root,COG1322@2|Bacteria	2|Bacteria	S	DNA recombination	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SYD2_k127_1753640_8	344747.PM8797T_01819	1.248e-11	78.0	COG3857@1|root,COG3857@2|Bacteria,2IZEK@203682|Planctomycetes	203682|Planctomycetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,Exonuc_V_gamma,PDDEXK_1,UvrD_C
SYD2_k127_1753640_4	1120973.AQXL01000133_gene1839	4.489e-37	160.0	COG3857@1|root,COG3857@2|Bacteria,1TVKS@1239|Firmicutes,4I3G1@91061|Bacilli,278HN@186823|Alicyclobacillaceae	91061|Bacilli	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SYD2_k127_1753640_2	756272.Plabr_4030	2.5e-57	203.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	ywlC1	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SYD2_k127_1753640_0	1123376.AUIU01000015_gene493	8.083e-128	414.0	COG0459@1|root,COG0459@2|Bacteria,3J0DA@40117|Nitrospirae	40117|Nitrospirae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SYD2_k127_1791806_0	671143.DAMO_0621	0.0	1442.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	Glyco_hydro_63
SYD2_k127_1791806_4	63737.Npun_F2216	4.188e-94	314.0	COG2258@1|root,COG2258@2|Bacteria,1G4BR@1117|Cyanobacteria,1HQ1K@1161|Nostocales	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
SYD2_k127_1791806_5	118173.KB235914_gene2349	4.768e-87	290.0	COG0431@1|root,COG0431@2|Bacteria,1G3AZ@1117|Cyanobacteria,1HAU3@1150|Oscillatoriales	1117|Cyanobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SYD2_k127_1791806_2	211165.AJLN01000061_gene3947	8.222e-146	470.0	COG0346@1|root,COG0346@2|Bacteria,1G29P@1117|Cyanobacteria,1JK2A@1189|Stigonemataceae	1117|Cyanobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SYD2_k127_1791806_1	861299.J421_1872	7.089e-264	820.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
SYD2_k127_1791806_7	861299.J421_1880	1.141e-55	199.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DM13
SYD2_k127_1791806_9	1125863.JAFN01000001_gene3571	1.253e-44	170.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,43AXT@68525|delta/epsilon subdivisions,2X6BZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SYD2_k127_1791806_12	1121116.KB894769_gene1376	1.037e-14	86.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2VIMU@28216|Betaproteobacteria,4AB9C@80864|Comamonadaceae	28216|Betaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SYD2_k127_1791806_10	682795.AciX8_3179	1.155e-42	171.0	COG1595@1|root,COG1595@2|Bacteria,3Y3BS@57723|Acidobacteria,2JIDF@204432|Acidobacteriia	204432|Acidobacteriia	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SYD2_k127_1791806_14	234267.Acid_7290	1.879e-09	64.0	COG5660@1|root,COG5660@2|Bacteria,3Y5KK@57723|Acidobacteria	57723|Acidobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SYD2_k127_1791806_11	977880.RALTA_A0817	5.629e-21	100.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2VIMU@28216|Betaproteobacteria,1JZUC@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SYD2_k127_1791806_3	1121939.L861_19245	1.191e-98	331.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1SZ0M@1236|Gammaproteobacteria,1XKZK@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SYD2_k127_1791806_6	102125.Xen7305DRAFT_00036380	7.668e-65	230.0	COG0572@1|root,COG0572@2|Bacteria,1G67K@1117|Cyanobacteria	1117|Cyanobacteria	F	uridine kinase	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
SYD2_k127_1791806_8	931627.MycrhDRAFT_3993	1.12e-44	167.0	COG3059@1|root,COG3059@2|Bacteria,2IIYH@201174|Actinobacteria,2398Q@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function, DUF417	-	-	-	-	-	-	-	-	-	-	-	-	DUF417
SYD2_k127_1791806_15	1408428.JNJP01000100_gene2092	4.778e-08	62.0	COG1359@1|root,COG1359@2|Bacteria,1NGPW@1224|Proteobacteria,42X22@68525|delta/epsilon subdivisions,2WSMI@28221|Deltaproteobacteria,2MDB7@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SYD2_k127_1791806_13	58123.JOFJ01000018_gene4300	5.333e-12	74.0	COG1917@1|root,COG1917@2|Bacteria,2IQ74@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_180287_3	234267.Acid_5981	3.772e-59	209.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SYD2_k127_180287_6	1192034.CAP_0302	1.234e-34	143.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	prp1	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
SYD2_k127_180287_0	1382359.JIAL01000001_gene2693	1.475e-136	464.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
SYD2_k127_180287_2	926690.KE386573_gene1707	2.202e-119	398.0	COG0477@1|root,arCOG00130@2157|Archaea,2XT8X@28890|Euryarchaeota,23TJU@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SYD2_k127_180287_4	393595.ABO_2666	5.329e-57	219.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T2N9@1236|Gammaproteobacteria,1XJNX@135619|Oceanospirillales	135619|Oceanospirillales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS_3
SYD2_k127_180287_1	204669.Acid345_2904	2.479e-129	427.0	COG1215@1|root,COG1215@2|Bacteria,3Y31I@57723|Acidobacteria,2JIKW@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SYD2_k127_180287_7	926566.Terro_1046	2.944e-21	97.0	COG1215@1|root,COG1215@2|Bacteria,3Y31I@57723|Acidobacteria,2JIKW@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SYD2_k127_180287_5	1047013.AQSP01000099_gene1495	3.452e-40	161.0	COG0805@1|root,COG0805@2|Bacteria,2NPGB@2323|unclassified Bacteria	2|Bacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SYD2_k127_18066_0	545243.BAEV01000080_gene2961	3.666e-167	545.0	COG1953@1|root,COG1953@2|Bacteria,1TS5W@1239|Firmicutes,247WK@186801|Clostridia,36VS3@31979|Clostridiaceae	186801|Clostridia	FH	PFAM Permease for cytosine purines, uracil, thiamine, allantoin	pucI	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
SYD2_k127_18066_2	84531.JMTZ01000166_gene1270	2.603e-25	114.0	COG2968@1|root,COG2968@2|Bacteria	2|Bacteria	S	cellular response to heat	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SYD2_k127_18066_1	661478.OP10G_4341	9.361e-66	230.0	COG2939@1|root,COG2939@2|Bacteria	2|Bacteria	E	PFAM Peptidase S10, serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
SYD2_k127_1811052_0	575540.Isop_3282	3.376e-250	790.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SYD2_k127_1811052_1	1340493.JNIF01000003_gene3658	2.374e-09	68.0	COG1240@1|root,COG1240@2|Bacteria,3Y474@57723|Acidobacteria	57723|Acidobacteria	H	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
SYD2_k127_1811052_2	1449063.JMLS01000006_gene3612	3.396e-06	49.0	2BKI8@1|root,32EZF@2|Bacteria,1TZNM@1239|Firmicutes,4I8XU@91061|Bacilli,270PJ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1849753_1	56107.Cylst_0473	2.043e-78	279.0	COG2215@1|root,COG2215@2|Bacteria,1G36H@1117|Cyanobacteria,1HQQ3@1161|Nostocales	1117|Cyanobacteria	S	High-affinity nickel-transport protein	-	-	-	ko:K08970	-	-	-	-	ko00000,ko02000	2.A.52.2	-	-	DsbD_2,NicO
SYD2_k127_1849753_2	234267.Acid_5048	4.512e-68	249.0	COG0457@1|root,COG0457@2|Bacteria,3Y7WN@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SYD2_k127_1849753_0	105420.BBPO01000031_gene6604	4.467e-82	284.0	2DB7W@1|root,2Z7P1@2|Bacteria,2GP9W@201174|Actinobacteria,2NEQS@228398|Streptacidiphilus	201174|Actinobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SYD2_k127_1856804_14	335543.Sfum_1368	2.521e-18	91.0	COG1399@1|root,COG1399@2|Bacteria,1N7GQ@1224|Proteobacteria,42U2P@68525|delta/epsilon subdivisions,2WRMV@28221|Deltaproteobacteria,2MS4U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SYD2_k127_1856804_17	903818.KI912268_gene1794	1.598e-07	59.0	COG0457@1|root,COG0457@2|Bacteria,3Y8SB@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2
SYD2_k127_1856804_4	1121920.AUAU01000004_gene638	7.558e-125	405.0	COG1250@1|root,COG1250@2|Bacteria,3Y3S5@57723|Acidobacteria	57723|Acidobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SYD2_k127_1856804_16	1198114.AciX9_0015	2.172e-08	63.0	2E5J5@1|root,2ZXJ9@2|Bacteria,3Y8T1@57723|Acidobacteria,2JNT6@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1856804_3	1198114.AciX9_1021	4.662e-158	508.0	COG0183@1|root,COG0183@2|Bacteria,3Y3SQ@57723|Acidobacteria,2JHU2@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SYD2_k127_1856804_8	383372.Rcas_3282	6.924e-81	281.0	COG1208@1|root,COG1208@2|Bacteria,2G65W@200795|Chloroflexi,376T2@32061|Chloroflexia	32061|Chloroflexia	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SYD2_k127_1856804_5	1123250.KB908398_gene1462	1.916e-122	407.0	COG1109@1|root,COG1109@2|Bacteria,1UDT8@1239|Firmicutes,4H27X@909932|Negativicutes	909932|Negativicutes	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	manB	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SYD2_k127_1856804_15	1209072.ALBT01000008_gene2953	1.56e-15	81.0	2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,1TB8R@1236|Gammaproteobacteria,1FIGQ@10|Cellvibrio	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3309
SYD2_k127_1856804_9	370438.PTH_1977	1.48e-59	216.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,260YT@186807|Peptococcaceae	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SYD2_k127_1856804_11	880073.Calab_1042	2.3e-37	145.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SYD2_k127_1856804_13	1487953.JMKF01000068_gene3266	7.732e-25	105.0	COG1598@1|root,COG1598@2|Bacteria,1G9X3@1117|Cyanobacteria,1HDAI@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SYD2_k127_1856804_12	449447.MAE_46130	1.846e-26	110.0	COG1724@1|root,COG1724@2|Bacteria,1G90Q@1117|Cyanobacteria	1117|Cyanobacteria	N	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SYD2_k127_1856804_2	1121920.AUAU01000004_gene813	1.677e-187	610.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3V0@57723|Acidobacteria	57723|Acidobacteria	EU	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
SYD2_k127_1856804_1	861299.J421_2678	1.079e-218	689.0	COG3104@1|root,COG3104@2|Bacteria,1ZSRG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SYD2_k127_1856804_7	991.IW20_10800	1.055e-83	298.0	COG3104@1|root,COG3104@2|Bacteria,4NGWH@976|Bacteroidetes,1HY6B@117743|Flavobacteriia,2NUAF@237|Flavobacterium	976|Bacteroidetes	U	Amino acid transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SYD2_k127_1856804_0	1379270.AUXF01000004_gene3330	6.957e-239	754.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1ZT6C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
SYD2_k127_1856804_10	1173264.KI913949_gene4298	1.173e-51	201.0	COG2059@1|root,COG2059@2|Bacteria,1G37Z@1117|Cyanobacteria,1HA7A@1150|Oscillatoriales	1117|Cyanobacteria	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SYD2_k127_1856804_6	237368.SCABRO_03561	6.755e-92	307.0	COG1090@1|root,COG1090@2|Bacteria,2IXEW@203682|Planctomycetes	203682|Planctomycetes	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
SYD2_k127_1860693_0	997346.HMPREF9374_1651	2.573e-119	428.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,27CSD@186824|Thermoactinomycetaceae	91061|Bacilli	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SYD2_k127_1860693_1	234267.Acid_0772	4.701e-32	132.0	COG0308@1|root,COG0457@1|root,COG0308@2|Bacteria,COG0457@2|Bacteria,3Y3C5@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1,TPR_11,TPR_16
SYD2_k127_1869691_2	401053.AciPR4_0923	1.053e-44	166.0	COG0206@1|root,COG0206@2|Bacteria,3Y2WG@57723|Acidobacteria,2JHRJ@204432|Acidobacteriia	204432|Acidobacteriia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SYD2_k127_1869691_0	316067.Geob_0785	3.081e-119	396.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,43SXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SYD2_k127_1869691_3	234267.Acid_7309	0.0001807	53.0	COG1589@1|root,COG1589@2|Bacteria,3Y3BQ@57723|Acidobacteria	57723|Acidobacteria	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SYD2_k127_1869691_1	479437.Elen_1438	4.867e-53	197.0	COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria,4CUE7@84998|Coriobacteriia	84998|Coriobacteriia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SYD2_k127_19130_6	234267.Acid_1953	2.15e-53	191.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_19130_5	644966.Tmar_1634	1.495e-59	211.0	COG1335@1|root,COG1335@2|Bacteria,1VI3P@1239|Firmicutes,24RP8@186801|Clostridia	186801|Clostridia	Q	PFAM Isochorismatase	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SYD2_k127_19130_7	665571.STHERM_c07040	7.972e-44	177.0	COG1488@1|root,COG1488@2|Bacteria,2J5IF@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
SYD2_k127_19130_9	1379698.RBG1_1C00001G1052	1.748e-40	160.0	COG0852@1|root,COG0852@2|Bacteria,2NPN6@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
SYD2_k127_19130_1	204669.Acid345_1289	1.098e-159	512.0	COG0649@1|root,COG0649@2|Bacteria,3Y3AB@57723|Acidobacteria,2JKWC@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SYD2_k127_19130_4	671143.DAMO_2695	7.5e-103	349.0	COG1005@1|root,COG1005@2|Bacteria,2NNTT@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SYD2_k127_19130_8	234267.Acid_5685	8.892e-42	159.0	COG1143@1|root,COG1143@2|Bacteria,3Y529@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
SYD2_k127_19130_10	879212.DespoDRAFT_00979	1.415e-34	136.0	2CCSR@1|root,32K43@2|Bacteria,1QJ8W@1224|Proteobacteria,43A9D@68525|delta/epsilon subdivisions,2X0VC@28221|Deltaproteobacteria,2MPDZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SYD2_k127_19130_12	234267.Acid_5686	3.018e-24	111.0	COG0839@1|root,COG0839@2|Bacteria,3Y5QU@57723|Acidobacteria	57723|Acidobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SYD2_k127_19130_11	204669.Acid345_1293	1.197e-28	119.0	COG0713@1|root,COG0713@2|Bacteria,3Y54E@57723|Acidobacteria,2JNK4@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SYD2_k127_19130_0	945713.IALB_1869	1.438e-169	561.0	COG1009@1|root,COG1009@2|Bacteria	2|Bacteria	CP	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SYD2_k127_19130_2	234267.Acid_5689	1.933e-150	494.0	COG1008@1|root,COG1008@2|Bacteria,3Y3VX@57723|Acidobacteria	57723|Acidobacteria	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SYD2_k127_19130_3	204669.Acid345_1296	1.218e-127	425.0	COG1007@1|root,COG1007@2|Bacteria,3Y43Y@57723|Acidobacteria,2JMDT@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SYD2_k127_19130_14	379066.GAU_3720	8.716e-15	76.0	28KW4@1|root,2ZACH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1936756_5	215803.DB30_8393	1.404e-70	256.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,42REB@68525|delta/epsilon subdivisions,2WNWD@28221|Deltaproteobacteria,2YUH8@29|Myxococcales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
SYD2_k127_1936756_2	1382359.JIAL01000001_gene558	1.937e-137	444.0	COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria,2JIUD@204432|Acidobacteriia	204432|Acidobacteriia	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SYD2_k127_1936756_1	272134.KB731324_gene3218	1.439e-171	564.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MHYT,PAS,PAS_3,PAS_9
SYD2_k127_1936756_7	1385518.N798_04180	3.295e-08	64.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,4FFWK@85021|Intrasporangiaceae	201174|Actinobacteria	S	Acetyltransferase	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
SYD2_k127_1936756_4	864051.BurJ1DRAFT_2047	6.091e-86	317.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VWI8@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SYD2_k127_1936756_6	109871.XP_006675052.1	2.379e-21	111.0	COG0542@1|root,KOG1051@2759|Eukaryota,38CTT@33154|Opisthokonta,3NWFJ@4751|Fungi	4751|Fungi	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small
SYD2_k127_1936756_0	903818.KI912268_gene2246	7.577e-254	806.0	COG0542@1|root,COG0542@2|Bacteria,3Y35D@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SYD2_k127_1936756_3	1382359.JIAL01000001_gene805	4.251e-134	460.0	COG4775@1|root,COG4775@2|Bacteria,3Y2Q9@57723|Acidobacteria,2JHYD@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SYD2_k127_1948467_3	204669.Acid345_4448	2.44e-26	121.0	COG1595@1|root,COG1595@2|Bacteria,3Y7TB@57723|Acidobacteria,2JMZD@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
SYD2_k127_1948467_2	330214.NIDE0244	8.166e-74	257.0	COG0602@1|root,COG0602@2|Bacteria,3J0M2@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
SYD2_k127_1948467_1	880073.Calab_2509	2.205e-88	297.0	COG0603@1|root,COG0603@2|Bacteria,2NPD6@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
SYD2_k127_1948467_4	1267535.KB906767_gene5189	8.743e-12	77.0	COG0457@1|root,COG0457@2|Bacteria,3Y3BD@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TPR_11,TPR_16,TPR_2,TPR_8
SYD2_k127_1948467_0	204669.Acid345_4047	6.755e-209	667.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria,2JKQG@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SYD2_k127_1955751_3	1121918.ARWE01000001_gene3366	4.952e-183	580.0	COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,42P6X@68525|delta/epsilon subdivisions,2WK8U@28221|Deltaproteobacteria,43U3A@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding
SYD2_k127_1955751_1	616991.JPOO01000003_gene1700	1.415e-225	708.0	COG1140@1|root,COG1140@2|Bacteria	2|Bacteria	C	nitrate reductase beta subunit	narH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	iAF987.Gmet_1021,iEcE24377_1341.EcE24377A_1376,iEcolC_1368.EcolC_2189	Fer4_11,Nitr_red_bet_C
SYD2_k127_1955751_9	1121920.AUAU01000008_gene1617	2.097e-23	109.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	narJ	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	-	ko:K00373,ko:K17052	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687	Nitrate_red_del
SYD2_k127_1955751_5	1121920.AUAU01000008_gene1616	9.202e-67	237.0	COG2181@1|root,COG2181@2|Bacteria	2|Bacteria	C	nitrate reductase activity	narI	GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204	1.7.5.1	ko:K00370,ko:K00374,ko:K02575	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00615,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.1.8,5.A.3.1	-	iEC042_1314.EC042_1594,iECABU_c1320.ECABU_c17020,iECUMN_1333.ECUMN_1718,iNJ661.Rv1164,iSF_1195.SF1230,ic_1306.c1897	Nitrate_red_gam
SYD2_k127_1955751_6	483219.LILAB_35270	7.509e-53	192.0	COG2010@1|root,COG2010@2|Bacteria,1P88Q@1224|Proteobacteria,43BRV@68525|delta/epsilon subdivisions,2X73R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
SYD2_k127_1955751_0	1121920.AUAU01000008_gene1614	1.259e-271	866.0	COG0437@1|root,COG0437@2|Bacteria,3Y2Z0@57723|Acidobacteria	2|Bacteria	C	4Fe-4S dicluster domain	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molydop_binding
SYD2_k127_1955751_2	1121920.AUAU01000008_gene1613	3.245e-207	655.0	COG5557@1|root,COG5557@2|Bacteria,3Y3NS@57723|Acidobacteria	57723|Acidobacteria	C	PFAM Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
SYD2_k127_1955751_7	246197.MXAN_5555	1.077e-44	168.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
SYD2_k127_1955751_8	1297742.A176_05067	1.724e-42	162.0	COG2010@1|root,COG2010@2|Bacteria,1RHGQ@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SYD2_k127_1955751_4	1278073.MYSTI_06128	1.939e-88	309.0	COG4531@1|root,COG4531@2|Bacteria,1REHQ@1224|Proteobacteria,42TZ1@68525|delta/epsilon subdivisions,2WQ6N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_1955751_10	42256.RradSPS_0572	4.678e-17	94.0	COG2223@1|root,COG2223@2|Bacteria,2GJ1I@201174|Actinobacteria,4CQM5@84995|Rubrobacteria	84995|Rubrobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
SYD2_k127_1999266_2	1210884.HG799468_gene13789	4.043e-33	143.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SYD2_k127_1999266_1	269798.CHU_0700	6.603e-36	142.0	COG2010@1|root,COG2010@2|Bacteria,4NQN1@976|Bacteroidetes,47XSN@768503|Cytophagia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
SYD2_k127_1999266_0	1121878.AUGL01000010_gene1060	2.549e-70	247.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,1RQAV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	walR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SYD2_k127_1999266_4	1042876.PPS_0201	2.376e-05	57.0	COG1413@1|root,COG1413@2|Bacteria,1R4SF@1224|Proteobacteria,1S2HV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SYD2_k127_1999266_3	272123.Anacy_5467	5.236e-10	68.0	COG1020@1|root,COG1020@2|Bacteria,1GBN8@1117|Cyanobacteria,1HQPV@1161|Nostocales	1117|Cyanobacteria	Q	Pfam:NRPS	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
SYD2_k127_2016067_7	1218075.BAYA01000005_gene1684	1.323e-50	190.0	COG0526@1|root,COG0526@2|Bacteria,1QTY9@1224|Proteobacteria,2WH1I@28216|Betaproteobacteria,1KG5X@119060|Burkholderiaceae	28216|Betaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SYD2_k127_2016067_5	1237149.C900_01352	1.258e-55	205.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,47PZ4@768503|Cytophagia	976|Bacteroidetes	O	peptide methionine sulfoxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SYD2_k127_2016067_8	1125863.JAFN01000001_gene3571	1.181e-49	184.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,43AXT@68525|delta/epsilon subdivisions,2X6BZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SYD2_k127_2016067_13	1112274.KI911560_gene1582	7.226e-09	61.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2W81G@28216|Betaproteobacteria,2KNB0@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SYD2_k127_2016067_2	1122179.KB890423_gene2365	1.951e-98	339.0	COG0296@1|root,COG1404@1|root,COG0296@2|Bacteria,COG1404@2|Bacteria,4NJ7Z@976|Bacteroidetes,1IZWQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
SYD2_k127_2016067_14	641149.HMPREF9016_01067	2.197e-05	50.0	29XXY@1|root,30JQH@2|Bacteria,1PJJV@1224|Proteobacteria,2WAYX@28216|Betaproteobacteria,2KTHX@206351|Neisseriales	206351|Neisseriales	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SYD2_k127_2016067_3	251229.Chro_3613	9.718e-96	322.0	COG0580@1|root,COG0580@2|Bacteria,1G3MJ@1117|Cyanobacteria	1117|Cyanobacteria	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SYD2_k127_2016067_9	861299.J421_1881	1.856e-45	175.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,HemolysinCabind,PD40
SYD2_k127_2016067_1	861299.J421_1875	8.799e-100	333.0	COG0662@1|root,COG3193@1|root,COG0662@2|Bacteria,COG3193@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Cupin_2,Haem_degrading
SYD2_k127_2016067_11	107636.JQNK01000009_gene3207	1.457e-35	141.0	COG3193@1|root,COG3193@2|Bacteria,1RGUD@1224|Proteobacteria,2UGI0@28211|Alphaproteobacteria,371DY@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
SYD2_k127_2016067_0	861299.J421_1876	6.778e-184	592.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
SYD2_k127_2016067_10	1121104.AQXH01000001_gene1649	1.545e-42	162.0	COG1595@1|root,COG1595@2|Bacteria,4NMIY@976|Bacteroidetes	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SYD2_k127_2016067_12	1121930.AQXG01000001_gene1317	3.827e-18	94.0	COG5343@1|root,COG5343@2|Bacteria	2|Bacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SYD2_k127_2016067_4	1396141.BATP01000022_gene241	5.256e-78	279.0	2DB7W@1|root,2Z7P1@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SYD2_k127_2016067_6	1267533.KB906736_gene883	3.944e-55	206.0	COG2215@1|root,COG2215@2|Bacteria,3Y79H@57723|Acidobacteria,2JM3I@204432|Acidobacteriia	204432|Acidobacteriia	S	High-affinity nickel-transport protein	-	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
SYD2_k127_2089125_0	886293.Sinac_6154	3.468e-186	613.0	COG2866@1|root,COG2866@2|Bacteria,2IXPH@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SYD2_k127_2089125_1	1380387.JADM01000015_gene1639	4.409e-19	94.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1SB50@1236|Gammaproteobacteria,1XM6N@135619|Oceanospirillales	135619|Oceanospirillales	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SYD2_k127_2096079_1	234267.Acid_3582	1.868e-77	288.0	COG4262@1|root,COG4262@2|Bacteria,3Y6HM@57723|Acidobacteria	57723|Acidobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2096079_3	234267.Acid_6474	3.09e-35	142.0	COG1943@1|root,COG1943@2|Bacteria,3Y8QI@57723|Acidobacteria	57723|Acidobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SYD2_k127_2096079_2	234267.Acid_3885	5.676e-48	176.0	COG1245@1|root,COG1245@2|Bacteria	2|Bacteria	C	4Fe-4S binding domain	rnfB	-	1.8.99.2	ko:K00395,ko:K02572,ko:K03616	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FeS,Fer4,Fer4_4,Fer4_7
SYD2_k127_2096079_0	204669.Acid345_3065	8.297e-194	620.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
SYD2_k127_2096079_4	204669.Acid345_4530	5.673e-26	114.0	COG4805@1|root,COG4805@2|Bacteria,3Y4PP@57723|Acidobacteria,2JKV8@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2101008_1	864051.BurJ1DRAFT_2047	4.955e-60	224.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VWI8@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SYD2_k127_2101008_0	247490.KSU1_C0173	8.956e-80	282.0	COG0303@1|root,COG0303@2|Bacteria,2IXJ1@203682|Planctomycetes	203682|Planctomycetes	H	Molybdenum cofactor synthesis domain protein	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SYD2_k127_2101008_3	204669.Acid345_4647	1.753e-51	187.0	COG0315@1|root,COG0315@2|Bacteria,3Y4IY@57723|Acidobacteria,2JJ7K@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SYD2_k127_2101008_4	1303518.CCALI_02289	8.813e-39	155.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
SYD2_k127_2101008_5	1541065.JRFE01000006_gene4670	0.0003437	49.0	2E789@1|root,331RY@2|Bacteria,1G9HM@1117|Cyanobacteria,3VKGK@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2101008_2	1121468.AUBR01000016_gene2299	3.97e-55	207.0	COG1565@1|root,COG1565@2|Bacteria,1V2II@1239|Firmicutes,24GK7@186801|Clostridia,42I8X@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
SYD2_k127_2123609_2	1267535.KB906767_gene2167	5.417e-60	212.0	COG2080@1|root,COG2080@2|Bacteria,3Y5EJ@57723|Acidobacteria,2JN23@204432|Acidobacteriia	204432|Acidobacteriia	C	[2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Fer2_2
SYD2_k127_2123609_0	1267535.KB906767_gene2168	8.581e-256	808.0	COG1529@1|root,COG1529@2|Bacteria,3Y3J7@57723|Acidobacteria,2JMHB@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K00256	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SYD2_k127_2123609_4	1123234.AUKI01000016_gene3057	3.307e-49	186.0	COG1808@1|root,COG1808@2|Bacteria,4P1J9@976|Bacteroidetes	976|Bacteroidetes	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2123609_3	240292.Ava_3740	9.522e-51	185.0	COG3467@1|root,COG3467@2|Bacteria,1G64G@1117|Cyanobacteria,1HS7G@1161|Nostocales	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SYD2_k127_2123609_1	204669.Acid345_3005	1.93e-210	692.0	COG0457@1|root,COG1305@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,3Y5KB@57723|Acidobacteria,2JHVK@204432|Acidobacteriia	204432|Acidobacteriia	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
SYD2_k127_2143616_0	1267533.KB906735_gene4448	4.116e-200	658.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y2YM@57723|Acidobacteria,2JKAC@204432|Acidobacteriia	204432|Acidobacteriia	K	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_17
SYD2_k127_2143616_1	349161.Dred_1868	6.311e-80	270.0	COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,24AN0@186801|Clostridia,262XA@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
SYD2_k127_2152674_0	234267.Acid_1953	7.259e-262	819.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2152674_2	1227739.Hsw_0423	2.406e-34	136.0	COG4899@1|root,COG4899@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2199
SYD2_k127_2152674_1	401526.TcarDRAFT_2158	3.731e-119	393.0	COG1063@1|root,COG1063@2|Bacteria,1U5GN@1239|Firmicutes	1239|Firmicutes	E	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SYD2_k127_2153386_3	1340493.JNIF01000003_gene1978	7.58e-128	426.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SYD2_k127_2153386_2	1216007.AOPM01000044_gene2844	8.491e-145	477.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,2Q185@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Zn-dependent peptidases	ptrA	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SYD2_k127_2153386_10	380358.XALC_2740	3.343e-41	157.0	COG1331@1|root,COG1331@2|Bacteria,1QWIF@1224|Proteobacteria,1T2VZ@1236|Gammaproteobacteria,1XD6X@135614|Xanthomonadales	135614|Xanthomonadales	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
SYD2_k127_2153386_0	1254432.SCE1572_17235	0.0	1323.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SYD2_k127_2153386_12	452637.Oter_1641	4.72e-34	135.0	2CCSR@1|root,32RWC@2|Bacteria,46WYJ@74201|Verrucomicrobia,3K9ZP@414999|Opitutae	414999|Opitutae	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SYD2_k127_2153386_5	1254432.SCE1572_17230	1.883e-93	324.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SYD2_k127_2153386_6	1379698.RBG1_1C00001G1080	7.593e-89	323.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SYD2_k127_2153386_4	1379698.RBG1_1C00001G1080	7.904e-94	338.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SYD2_k127_2153386_14	545276.KB898734_gene2306	1.129e-17	88.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,1S67R@1236|Gammaproteobacteria,1WY6Z@135613|Chromatiales	135613|Chromatiales	KT	response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SYD2_k127_2153386_15	1267533.KB906740_gene145	2.999e-14	77.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	MA20_44825	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SYD2_k127_2153386_7	269799.Gmet_0066	1.681e-81	287.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,42P2T@68525|delta/epsilon subdivisions,2WJ9B@28221|Deltaproteobacteria,43SU2@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
SYD2_k127_2153386_16	1043205.AFYF01000045_gene2910	0.000126	52.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4FFCB@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SYD2_k127_2153386_8	479434.Sthe_1685	8.768e-76	261.0	COG0036@1|root,COG0036@2|Bacteria,2G6EU@200795|Chloroflexi,27Y7N@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the ribulose-phosphate 3-epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SYD2_k127_2153386_13	682795.AciX8_4624	7.664e-29	133.0	COG4105@1|root,COG4105@2|Bacteria,3Y36S@57723|Acidobacteria,2JHVA@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM Outer membrane assembly lipoprotein YfiO	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
SYD2_k127_2153386_1	1254432.SCE1572_26460	1.196e-157	529.0	COG1196@1|root,COG1352@1|root,COG2201@1|root,COG5002@1|root,COG1196@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CHASE3,CheB_methylest,CheR,CheR_N,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SYD2_k127_2153386_9	187272.Mlg_1115	2.825e-44	173.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,1RP0B@1236|Gammaproteobacteria,1WX6H@135613|Chromatiales	135613|Chromatiales	K	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
SYD2_k127_2153386_11	335543.Sfum_3325	6.705e-41	154.0	COG0438@1|root,COG0662@1|root,COG0438@2|Bacteria,COG0662@2|Bacteria,1MWSZ@1224|Proteobacteria,42NYZ@68525|delta/epsilon subdivisions,2WK9U@28221|Deltaproteobacteria,2MQ7Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,MannoseP_isomer
SYD2_k127_2167727_5	1499967.BAYZ01000009_gene5270	9.996e-87	315.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	ywqD	-	2.7.10.1	ko:K08252,ko:K13661,ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
SYD2_k127_2167727_9	335543.Sfum_0973	2.294e-59	210.0	COG0110@1|root,COG0110@2|Bacteria,1PFB8@1224|Proteobacteria,439Z7@68525|delta/epsilon subdivisions,2X1Z1@28221|Deltaproteobacteria,2MSCA@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SYD2_k127_2167727_2	211165.AJLN01000116_gene3438	2.97e-135	440.0	COG0399@1|root,COG0399@2|Bacteria,1G0IM@1117|Cyanobacteria,1JJ7R@1189|Stigonemataceae	1117|Cyanobacteria	M	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SYD2_k127_2167727_3	1519464.HY22_10225	6.937e-126	413.0	COG0673@1|root,COG0673@2|Bacteria,1FEZX@1090|Chlorobi	1090|Chlorobi	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SYD2_k127_2167727_1	330214.NIDE3012	1.394e-162	519.0	COG1089@1|root,COG1089@2|Bacteria,3J0YR@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SYD2_k127_2167727_12	1267533.KB906735_gene4494	2.034e-26	127.0	COG1749@1|root,COG4257@1|root,COG4932@1|root,COG1749@2|Bacteria,COG4257@2|Bacteria,COG4932@2|Bacteria,3Y930@57723|Acidobacteria	57723|Acidobacteria	M	Flagellar hook protein flgE	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4082
SYD2_k127_2167727_11	316274.Haur_3231	1.988e-32	139.0	COG1215@1|root,COG1215@2|Bacteria,2G6E4@200795|Chloroflexi,375A8@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
SYD2_k127_2167727_6	316274.Haur_3712	1.007e-73	263.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SYD2_k127_2167727_7	1313301.AUGC01000001_gene1578	7.517e-68	244.0	COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SYD2_k127_2167727_10	1121015.N789_03400	1.041e-57	209.0	COG0110@1|root,COG0110@2|Bacteria,1NMFJ@1224|Proteobacteria	1224|Proteobacteria	S	maltose O-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SYD2_k127_2167727_15	316274.Haur_3709	1.504e-18	99.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SYD2_k127_2167727_0	1123242.JH636434_gene4587	1.1e-180	584.0	COG0367@1|root,COG0367@2|Bacteria,2IXAI@203682|Planctomycetes	203682|Planctomycetes	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SYD2_k127_2167727_14	380394.Lferr_0080	5.968e-25	116.0	COG2227@1|root,COG2227@2|Bacteria,1RHSX@1224|Proteobacteria,1SEB0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SYD2_k127_2167727_4	330214.NIDE3016	3.816e-118	384.0	COG1209@1|root,COG1209@2|Bacteria,3J0KX@40117|Nitrospirae	40117|Nitrospirae	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SYD2_k127_2167727_8	243231.GSU2082	3.833e-62	217.0	COG1898@1|root,COG1898@2|Bacteria,1RGRQ@1224|Proteobacteria	1224|Proteobacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SYD2_k127_2167727_13	1499967.BAYZ01000186_gene3970	1.133e-25	111.0	COG0438@1|root,COG0438@2|Bacteria,2NR2T@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SYD2_k127_2170982_2	1121422.AUMW01000010_gene1135	3.711e-33	143.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,248FR@186801|Clostridia,260M7@186807|Peptococcaceae	186801|Clostridia	M	UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase	ugtP	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
SYD2_k127_2170982_1	1122921.KB898201_gene3195	2.571e-37	155.0	COG0535@1|root,COG0535@2|Bacteria,1UXWS@1239|Firmicutes	1239|Firmicutes	C	Radical SAM	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SYD2_k127_2170982_5	935863.AWZR01000005_gene2236	5.735e-05	51.0	2AQ2A@1|root,31F7E@2|Bacteria,1QCMG@1224|Proteobacteria,1T8CS@1236|Gammaproteobacteria,1XAFU@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2170982_0	211165.AJLN01000084_gene1825	1.531e-44	176.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SYD2_k127_2170982_3	1476973.JMMB01000007_gene3240	1.918e-23	114.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,24C7H@186801|Clostridia,25UIJ@186804|Peptostreptococcaceae	186801|Clostridia	M	SurA N-terminal domain	prsA	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SYD2_k127_2170982_4	649638.Trad_2541	2.265e-11	64.0	COG1764@1|root,COG1764@2|Bacteria,1WJVD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	redox protein regulator of disulfide bond formation	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SYD2_k127_2174923_1	1295642.H839_06979	1.43e-65	233.0	COG1082@1|root,COG1082@2|Bacteria,1TS20@1239|Firmicutes,4HD4V@91061|Bacilli,1WG70@129337|Geobacillus	91061|Bacilli	G	Xylose isomerase-like TIM barrel	iolI	-	5.3.99.11	ko:K06606	ko00562,ko01120,map00562,map01120	-	R09952	RC01513	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SYD2_k127_2174923_0	235909.GK1899	5.558e-89	304.0	COG0673@1|root,COG0673@2|Bacteria,1TW1D@1239|Firmicutes,4I4QS@91061|Bacilli,1WFPB@129337|Geobacillus	91061|Bacilli	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SYD2_k127_2180887_1	945713.IALB_1242	9.295e-234	744.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria	2|Bacteria	C	oxoglutarate dehydrogenase (succinyl-transferring) activity	sucA	GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c,iSSON_1240.SSON_0677,iYL1228.KPN_00732	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SYD2_k127_2180887_10	1120949.KB903294_gene4037	3.021e-28	121.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	lpqD	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009628,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036293,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SYD2_k127_2180887_2	234267.Acid_6651	1.071e-178	578.0	COG0154@1|root,COG0154@2|Bacteria,3Y3E5@57723|Acidobacteria	57723|Acidobacteria	J	PFAM Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
SYD2_k127_2180887_13	861299.J421_1405	3.296e-19	92.0	2A4E9@1|root,2ZJRI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2180887_4	316067.Geob_2159	9.231e-82	296.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,43S5Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase homodimeric	cheA40H	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SYD2_k127_2180887_9	204669.Acid345_1215	1.723e-32	132.0	COG0781@1|root,COG0781@2|Bacteria,3Y4Z7@57723|Acidobacteria,2JJFX@204432|Acidobacteriia	204432|Acidobacteriia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SYD2_k127_2180887_8	335543.Sfum_1381	1.627e-44	166.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,42RQ6@68525|delta/epsilon subdivisions,2WNCZ@28221|Deltaproteobacteria,2MQEK@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SYD2_k127_2180887_11	234267.Acid_4894	5.729e-26	114.0	COG2365@1|root,COG2365@2|Bacteria,3Y8BW@57723|Acidobacteria	57723|Acidobacteria	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase2
SYD2_k127_2180887_7	1340493.JNIF01000003_gene2546	4.061e-63	229.0	2EZNS@1|root,33STS@2|Bacteria,3Y75C@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2180887_12	1210884.HG799462_gene8483	2.894e-24	109.0	COG0517@1|root,COG0517@2|Bacteria,2J0MQ@203682|Planctomycetes	203682|Planctomycetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SYD2_k127_2180887_3	314230.DSM3645_04355	3.453e-146	471.0	COG1013@1|root,COG1013@2|Bacteria,2IY6Z@203682|Planctomycetes	203682|Planctomycetes	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SYD2_k127_2180887_0	945713.IALB_1501	2.557e-256	804.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	korA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SYD2_k127_2180887_14	1210884.HG799462_gene8487	7.327e-17	87.0	COG0517@1|root,COG0517@2|Bacteria,2J0FD@203682|Planctomycetes	203682|Planctomycetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SYD2_k127_2180887_5	234267.Acid_3611	5.789e-70	250.0	COG1734@1|root,COG2208@1|root,COG1734@2|Bacteria,COG2208@2|Bacteria,3Y4RV@57723|Acidobacteria	57723|Acidobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SYD2_k127_2180887_6	1173023.KE650771_gene4026	1.112e-67	238.0	COG1104@1|root,COG1104@2|Bacteria,1G0D5@1117|Cyanobacteria,1JICP@1189|Stigonemataceae	1117|Cyanobacteria	E	Beta-eliminating lyase	nifS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SYD2_k127_2183889_0	1379698.RBG1_1C00001G0780	8.721e-143	458.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
SYD2_k127_2183889_3	765420.OSCT_2410	3.991e-10	60.0	COG0614@1|root,COG0614@2|Bacteria,2G9KR@200795|Chloroflexi,377DT@32061|Chloroflexia	32061|Chloroflexia	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
SYD2_k127_2183889_2	765420.OSCT_2410	1.554e-29	119.0	COG0614@1|root,COG0614@2|Bacteria,2G9KR@200795|Chloroflexi,377DT@32061|Chloroflexia	32061|Chloroflexia	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
SYD2_k127_2183889_1	1379698.RBG1_1C00001G0781	3.846e-53	191.0	COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	petA	-	1.10.2.2,1.10.9.1	ko:K00411,ko:K02636,ko:K03886	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske,UCR_Fe-S_N
SYD2_k127_2183889_4	1340493.JNIF01000003_gene1663	8.633e-10	65.0	28MCK@1|root,2ZAQP@2|Bacteria,3Y41I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2228894_2	243231.GSU0895	1.24e-62	236.0	COG2199@1|root,COG2203@1|root,COG4936@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG4936@2|Bacteria,1MZV7@1224|Proteobacteria,43AIQ@68525|delta/epsilon subdivisions,2X5YZ@28221|Deltaproteobacteria,43W31@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PocR
SYD2_k127_2228894_0	309801.trd_1630	1.481e-129	426.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,27XY8@189775|Thermomicrobia	189775|Thermomicrobia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SYD2_k127_2228894_1	251221.35214697	6.762e-112	367.0	COG0444@1|root,COG0444@2|Bacteria,1G1NU@1117|Cyanobacteria	1117|Cyanobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SYD2_k127_2247059_10	114615.BRADO0086	1.02e-59	208.0	COG1793@1|root,COG1793@2|Bacteria,1R4SI@1224|Proteobacteria,2U213@28211|Alphaproteobacteria,3JW0F@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	ATP dependent DNA ligase C terminal region	ligC	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SYD2_k127_2247059_2	1429046.RR21198_0312	6.974e-258	814.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria	201174|Actinobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SYD2_k127_2247059_16	903818.KI912269_gene428	1.029e-05	56.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SYD2_k127_2247059_3	1382306.JNIM01000001_gene1328	4.087e-162	527.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SYD2_k127_2247059_14	945713.IALB_2785	1.047e-28	117.0	COG1393@1|root,COG1393@2|Bacteria	2|Bacteria	P	arsenate reductase (glutaredoxin) activity	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
SYD2_k127_2247059_7	1183438.GKIL_2285	7.161e-75	258.0	COG0400@1|root,COG0400@2|Bacteria,1G3RX@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase
SYD2_k127_2247059_4	330214.NIDE1676	6.262e-162	522.0	COG1066@1|root,COG1066@2|Bacteria,3J0BP@40117|Nitrospirae	40117|Nitrospirae	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI,Lon_C
SYD2_k127_2247059_1	1173021.ALWA01000020_gene83	2.142e-286	904.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,1G3SH@1117|Cyanobacteria	2|Bacteria	M	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,F5_F8_type_C,Lactonase,Phosphoesterase,SGL
SYD2_k127_2247059_0	234267.Acid_7252	0.0	1439.0	COG4447@1|root,COG4447@2|Bacteria,3Y69Z@57723|Acidobacteria	57723|Acidobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SYD2_k127_2247059_6	215803.DB30_6474	1.043e-75	286.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YWWP@29|Myxococcales	28221|Deltaproteobacteria	KLT	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase,Pkinase_Tyr,WD40
SYD2_k127_2247059_11	502025.Hoch_1576	2.458e-58	209.0	COG1595@1|root,COG1595@2|Bacteria,1RINW@1224|Proteobacteria,4385N@68525|delta/epsilon subdivisions,2X3FI@28221|Deltaproteobacteria,2YVVV@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SYD2_k127_2247059_8	497965.Cyan7822_2631	7.938e-66	239.0	COG0419@1|root,COG2319@1|root,COG0419@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,3KH8A@43988|Cyanothece	1117|Cyanobacteria	L	WD-40 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	WD40
SYD2_k127_2247059_5	886293.Sinac_0410	6.831e-106	380.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
SYD2_k127_2247059_12	234267.Acid_7677	5.533e-51	188.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SYD2_k127_2247059_9	1285586.H131_12663	1.745e-65	242.0	COG3391@1|root,COG3391@2|Bacteria,1V255@1239|Firmicutes,4HFUF@91061|Bacilli,3IXHK@400634|Lysinibacillus	91061|Bacilli	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase,PD40,Phosphoesterase
SYD2_k127_2261208_1	204669.Acid345_4299	8.039e-66	243.0	COG1193@1|root,COG1193@2|Bacteria,3Y2Z2@57723|Acidobacteria,2JHU4@204432|Acidobacteriia	204432|Acidobacteriia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SYD2_k127_2261208_0	373903.Hore_12410	1.612e-104	355.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3WAEK@53433|Halanaerobiales	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
SYD2_k127_2271116_10	204669.Acid345_4683	9.062e-19	86.0	COG0267@1|root,COG0267@2|Bacteria,3Y5UB@57723|Acidobacteria,2JJXX@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SYD2_k127_2271116_12	2325.TKV_c20710	8.333e-05	51.0	COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes,24UI4@186801|Clostridia,42HCB@68295|Thermoanaerobacterales	186801|Clostridia	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SYD2_k127_2271116_5	204669.Acid345_4681	1.542e-58	209.0	COG0250@1|root,COG0250@2|Bacteria,3Y3ZR@57723|Acidobacteria,2JHU8@204432|Acidobacteriia	204432|Acidobacteriia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SYD2_k127_2271116_11	414684.RC1_0696	2.371e-13	71.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,2TRID@28211|Alphaproteobacteria,2JQKK@204441|Rhodospirillales	204441|Rhodospirillales	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SYD2_k127_2271116_4	1158182.KB905034_gene1620	2.22e-62	217.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,1WXZD@135613|Chromatiales	135613|Chromatiales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SYD2_k127_2271116_3	903818.KI912268_gene2416	6.04e-89	299.0	COG0081@1|root,COG0081@2|Bacteria,3Y2HX@57723|Acidobacteria	57723|Acidobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SYD2_k127_2271116_8	204669.Acid345_4678	1.454e-41	159.0	COG0244@1|root,COG0244@2|Bacteria,3Y4N2@57723|Acidobacteria,2JJ81@204432|Acidobacteriia	204432|Acidobacteriia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SYD2_k127_2271116_7	1267535.KB906767_gene4468	6.786e-46	169.0	COG0222@1|root,COG0222@2|Bacteria,3Y50J@57723|Acidobacteria,2JJHE@204432|Acidobacteriia	204432|Acidobacteriia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SYD2_k127_2271116_1	234267.Acid_5457	0.0	1924.0	COG0085@1|root,COG0085@2|Bacteria,3Y36G@57723|Acidobacteria	57723|Acidobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SYD2_k127_2271116_0	234267.Acid_5456	0.0	1988.0	COG0086@1|root,COG0086@2|Bacteria,3Y2FZ@57723|Acidobacteria	57723|Acidobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SYD2_k127_2271116_6	247490.KSU1_C1161	1.408e-53	205.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	yidC	-	-	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,DUF4124,PDZ_2,Peptidase_C11,SLH,TPM_phosphatase,TPR_11,Trypsin_2,YidC_periplas
SYD2_k127_2271116_9	1121459.AQXE01000013_gene2224	1.697e-33	138.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,42MVW@68525|delta/epsilon subdivisions,2WKKC@28221|Deltaproteobacteria,2M8Q6@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	hdrF	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SYD2_k127_2271116_2	639030.JHVA01000001_gene70	2.335e-134	449.0	COG1022@1|root,COG1022@2|Bacteria,3Y2KU@57723|Acidobacteria,2JHTA@204432|Acidobacteriia	204432|Acidobacteriia	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SYD2_k127_2280518_0	945713.IALB_1501	1.378e-255	801.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	korA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SYD2_k127_2280518_1	530564.Psta_0806	3.972e-150	484.0	COG1013@1|root,COG1013@2|Bacteria,2IY6Z@203682|Planctomycetes	203682|Planctomycetes	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SYD2_k127_2293966_7	697303.Thewi_2114	1.148e-55	199.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
SYD2_k127_2293966_0	1379270.AUXF01000003_gene3550	0.0	1563.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SYD2_k127_2293966_4	204669.Acid345_3039	5.953e-121	406.0	28NTH@1|root,2ZBS4@2|Bacteria,3Y3NN@57723|Acidobacteria,2JIEU@204432|Acidobacteriia	204432|Acidobacteriia	S	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
SYD2_k127_2293966_8	909663.KI867150_gene69	4.288e-55	198.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2293966_9	565033.GACE_0089	1.202e-36	141.0	COG1917@1|root,arCOG03004@2157|Archaea,2XYUR@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SYD2_k127_2293966_2	247490.KSU1_D0632	3.628e-172	546.0	COG1275@1|root,COG1275@2|Bacteria,2J2HB@203682|Planctomycetes	203682|Planctomycetes	P	Voltage-dependent anion channel	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
SYD2_k127_2293966_3	1254432.SCE1572_23370	5.68e-140	455.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2293966_1	1254432.SCE1572_23375	0.0	1168.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2X7DH@28221|Deltaproteobacteria,2YWG8@29|Myxococcales	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	nasC	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SYD2_k127_2293966_5	1254432.SCE1572_23380	1.636e-94	314.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_4
SYD2_k127_2293966_6	1254432.SCE1572_23385	7.771e-58	207.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SYD2_k127_2293966_11	316274.Haur_1542	3.234e-17	83.0	2DDP8@1|root,2ZISD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2293966_10	316274.Haur_1544	5.55e-31	124.0	COG2223@1|root,COG2223@2|Bacteria	316274.Haur_1544|-	P	nitrite transmembrane transporter activity	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	-
SYD2_k127_2349073_1	378806.STAUR_1528	1.712e-43	171.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
SYD2_k127_2349073_2	326427.Cagg_0539	4.305e-42	161.0	COG1268@1|root,COG1268@2|Bacteria,2G969@200795|Chloroflexi,375QP@32061|Chloroflexia	32061|Chloroflexia	S	PFAM BioY protein	-	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SYD2_k127_2349073_0	204669.Acid345_1918	2.714e-286	887.0	COG3808@1|root,COG3808@2|Bacteria,3Y34E@57723|Acidobacteria,2JJHT@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SYD2_k127_236381_1	1382359.JIAL01000001_gene1753	4.773e-242	766.0	COG0187@1|root,COG0187@2|Bacteria,3Y369@57723|Acidobacteria,2JI1D@204432|Acidobacteriia	204432|Acidobacteriia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SYD2_k127_236381_0	234267.Acid_0882	7.742e-273	852.0	COG0154@1|root,COG0154@2|Bacteria,3Y2N6@57723|Acidobacteria	57723|Acidobacteria	J	PFAM Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
SYD2_k127_2394179_7	1267533.KB906737_gene1500	7.041e-16	80.0	2DUQS@1|root,33RT2@2|Bacteria,3Y6EQ@57723|Acidobacteria,2JMHN@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2394179_2	1403819.BATR01000118_gene4116	1.625e-83	286.0	COG1940@1|root,COG1940@2|Bacteria,46T0E@74201|Verrucomicrobia	74201|Verrucomicrobia	GK	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SYD2_k127_2394179_4	204669.Acid345_0659	4.285e-79	272.0	COG1349@1|root,COG1349@2|Bacteria,3Y7AH@57723|Acidobacteria,2JMHS@204432|Acidobacteriia	204432|Acidobacteriia	K	DeoR C terminal sensor domain	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
SYD2_k127_2394179_1	240015.ACP_0859	4.263e-103	347.0	COG2222@1|root,COG2222@2|Bacteria,3Y3W8@57723|Acidobacteria,2JHQD@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM Sugar isomerase (SIS)	-	-	-	ko:K02082	-	-	-	-	ko00000,ko01000	-	-	-	SIS
SYD2_k127_2394179_3	1267533.KB906737_gene1887	2.412e-81	281.0	COG0524@1|root,COG0524@2|Bacteria,3Y44M@57723|Acidobacteria,2JIAD@204432|Acidobacteriia	204432|Acidobacteriia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SYD2_k127_2394179_5	697303.Thewi_0214	1.014e-68	247.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,42EMP@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM ketose-bisphosphate aldolase, class-II	-	-	4.1.2.40	ko:K08302	ko00052,ko01100,map00052,map01100	-	R01069	RC00438,RC00439	ko00000,ko00001,ko01000	-	-	-	F_bP_aldolase
SYD2_k127_2394179_0	1123242.JH636434_gene4856	9.341e-206	651.0	COG0591@1|root,COG0591@2|Bacteria,2J2KC@203682|Planctomycetes	203682|Planctomycetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SYD2_k127_2394179_6	204669.Acid345_0661	1.156e-64	233.0	COG1105@1|root,COG1105@2|Bacteria,3Y5F9@57723|Acidobacteria,2JNDJ@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphomethylpyrimidine kinase	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SYD2_k127_2394179_8	1028800.RG540_PA12070	2.072e-08	65.0	COG0673@1|root,COG0673@2|Bacteria,1MUP0@1224|Proteobacteria,2TT57@28211|Alphaproteobacteria,4B9UJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SYD2_k127_2400448_4	177439.DPPB82	1.1e-19	100.0	COG3307@1|root,COG3307@2|Bacteria,1N225@1224|Proteobacteria,42QDQ@68525|delta/epsilon subdivisions,2WM6B@28221|Deltaproteobacteria,2MJQS@213118|Desulfobacterales	28221|Deltaproteobacteria	M	O-Antigen ligase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	TPR_14,TPR_16,TPR_8,Wzy_C
SYD2_k127_2400448_0	484770.UFO1_4161	9.756e-141	471.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,4H1ZX@909932|Negativicutes	909932|Negativicutes	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
SYD2_k127_2400448_1	1170562.Cal6303_4712	4.151e-58	217.0	COG1216@1|root,COG1216@2|Bacteria,1G3T8@1117|Cyanobacteria,1HNFR@1161|Nostocales	1117|Cyanobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
SYD2_k127_2400448_2	118168.MC7420_2498	3.874e-50	185.0	COG3751@1|root,COG3751@2|Bacteria,1GGCA@1117|Cyanobacteria	1117|Cyanobacteria	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2400448_3	639030.JHVA01000001_gene82	7.031e-23	101.0	COG1215@1|root,COG1215@2|Bacteria,3Y6JG@57723|Acidobacteria,2JM93@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SYD2_k127_2430013_0	682795.AciX8_4808	3.154e-61	229.0	COG1940@1|root,COG1940@2|Bacteria,3Y3B2@57723|Acidobacteria,2JIYY@204432|Acidobacteriia	204432|Acidobacteriia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SYD2_k127_2430013_1	1340493.JNIF01000003_gene4277	7.95e-14	77.0	COG1396@1|root,COG1396@2|Bacteria,3Y5UK@57723|Acidobacteria	57723|Acidobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2430013_2	1408444.JHYC01000020_gene201	4.301e-06	56.0	COG1396@1|root,COG2856@1|root,COG1396@2|Bacteria,COG2856@2|Bacteria,1NEHF@1224|Proteobacteria,1RMJ3@1236|Gammaproteobacteria,1JFRV@118969|Legionellales	118969|Legionellales	K	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_M78
SYD2_k127_2430013_3	1005395.CSV86_07996	4.824e-05	51.0	COG1396@1|root,COG1396@2|Bacteria,1QXQB@1224|Proteobacteria,1T3GB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SYD2_k127_2472374_1	234267.Acid_7923	1.652e-96	332.0	COG1228@1|root,COG1228@2|Bacteria,3Y47R@57723|Acidobacteria	57723|Acidobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SYD2_k127_2472374_0	861299.J421_1410	4.21e-157	505.0	COG0624@1|root,COG0624@2|Bacteria,1ZSYH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SYD2_k127_2519727_10	247490.KSU1_C1660	1.28e-18	93.0	COG1943@1|root,COG1943@2|Bacteria,2J110@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SYD2_k127_2519727_11	986075.CathTA2_1858	3.477e-11	64.0	COG1225@1|root,COG1225@2|Bacteria,1VGP9@1239|Firmicutes,4HQ3V@91061|Bacilli	91061|Bacilli	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SYD2_k127_2519727_8	986075.CathTA2_1857	7.839e-39	147.0	COG1225@1|root,COG1225@2|Bacteria,1V6MU@1239|Firmicutes,4HK8J@91061|Bacilli	91061|Bacilli	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SYD2_k127_2519727_6	485913.Krac_9819	5.111e-42	158.0	2DQBG@1|root,335T7@2|Bacteria,2G96K@200795|Chloroflexi	200795|Chloroflexi	C	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	-	-	-	-	-	-	-	-	-	-	GRDB
SYD2_k127_2519727_0	378806.STAUR_0362	3.537e-150	484.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,42QCN@68525|delta/epsilon subdivisions,2WIYT@28221|Deltaproteobacteria,2YV4K@29|Myxococcales	28221|Deltaproteobacteria	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SYD2_k127_2519727_1	189753.AXAS01000013_gene5867	2.994e-111	369.0	COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,2TRQ1@28211|Alphaproteobacteria,3JSJF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
SYD2_k127_2519727_5	452637.Oter_2173	2.604e-54	196.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SYD2_k127_2519727_4	395964.KE386496_gene1500	4.444e-73	254.0	COG3945@1|root,COG3945@2|Bacteria,1NX3S@1224|Proteobacteria,2U1MQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Pfam Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SYD2_k127_2519727_7	221288.JH992901_gene1687	7.431e-40	149.0	COG1695@1|root,COG1695@2|Bacteria,1GDRG@1117|Cyanobacteria	1117|Cyanobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SYD2_k127_2519727_3	1123277.KB893192_gene4324	1.172e-96	336.0	COG3667@1|root,COG3667@2|Bacteria,4NICY@976|Bacteroidetes,47KK4@768503|Cytophagia	976|Bacteroidetes	P	copper resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2519727_2	1382359.JIAL01000001_gene350	3.178e-98	329.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	rip3	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031224,GO:0031226,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50,Peptidase_M50B
SYD2_k127_2533704_0	886293.Sinac_6462	2.061e-164	522.0	COG0451@1|root,COG0451@2|Bacteria,2IX7V@203682|Planctomycetes	203682|Planctomycetes	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SYD2_k127_2533704_1	439235.Dalk_0708	9.087e-124	419.0	COG0472@1|root,COG1086@1|root,COG0472@2|Bacteria,COG1086@2|Bacteria,1MWYW@1224|Proteobacteria,42NVY@68525|delta/epsilon subdivisions,2X5IH@28221|Deltaproteobacteria,2MQ3P@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
SYD2_k127_2533704_2	90675.XP_010450900.1	9.789e-06	57.0	KOG1125@1|root,KOG1125@2759|Eukaryota,37K0D@33090|Viridiplantae,3GE1B@35493|Streptophyta,3HQ00@3699|Brassicales	35493|Streptophyta	S	Tetratricopeptide repeat	-	GO:0000268,GO:0003674,GO:0005048,GO:0005052,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005778,GO:0005829,GO:0006605,GO:0006625,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0009719,GO:0009725,GO:0009733,GO:0009987,GO:0010033,GO:0015031,GO:0015833,GO:0015919,GO:0016020,GO:0016043,GO:0016558,GO:0016560,GO:0017038,GO:0031090,GO:0031903,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042221,GO:0042277,GO:0042579,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043574,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044743,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:0098588,GO:0098805	-	ko:K13342	ko04146,map04146	-	-	-	ko00000,ko00001,ko04131	3.A.20.1	-	-	TPR_1,TPR_11,TPR_16,TPR_8
SYD2_k127_2559584_9	768670.Calni_0052	3.241e-23	113.0	COG1452@1|root,COG1452@2|Bacteria,2GEPI@200930|Deferribacteres	200930|Deferribacteres	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_2
SYD2_k127_2559584_3	1499967.BAYZ01000178_gene4651	6.093e-84	292.0	COG0763@1|root,COG0763@2|Bacteria,2NP10@2323|unclassified Bacteria	2|Bacteria	I	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
SYD2_k127_2559584_4	204669.Acid345_2272	5.27e-83	288.0	COG2010@1|root,COG2010@2|Bacteria,3Y5ZT@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SYD2_k127_2559584_11	218284.CCDN010000008_gene4049	2.834e-10	69.0	COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1TP24@1239|Firmicutes,4HA77@91061|Bacilli,1ZCHY@1386|Bacillus	91061|Bacilli	M	COG1388 FOG LysM repeat	cwlS	-	-	ko:K19223,ko:K19224	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	LysM,NLPC_P60,SH3_3
SYD2_k127_2559584_7	1254432.SCE1572_04190	1.623e-50	183.0	COG0727@1|root,COG0727@2|Bacteria,1N5PC@1224|Proteobacteria	1224|Proteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SYD2_k127_2559584_0	251221.35211608	9.095e-159	509.0	COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
SYD2_k127_2559584_6	1047013.AQSP01000057_gene1926	1.097e-62	231.0	COG1253@1|root,COG1253@2|Bacteria,2NP9I@2323|unclassified Bacteria	2|Bacteria	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SYD2_k127_2559584_8	1198114.AciX9_2971	2.545e-26	113.0	COG0319@1|root,COG0319@2|Bacteria,3Y53R@57723|Acidobacteria,2JJPS@204432|Acidobacteriia	204432|Acidobacteriia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SYD2_k127_2559584_1	204669.Acid345_3538	1.353e-114	377.0	COG1702@1|root,COG1702@2|Bacteria,3Y3RM@57723|Acidobacteria,2JI4V@204432|Acidobacteriia	204432|Acidobacteriia	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SYD2_k127_2559584_10	314285.KT71_18132	1.267e-19	95.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,1SNY3@1236|Gammaproteobacteria,1JA8N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SYD2_k127_2559584_12	179408.Osc7112_1290	1.252e-07	58.0	2E4KA@1|root,32ZF9@2|Bacteria,1G7KH@1117|Cyanobacteria,1HD7J@1150|Oscillatoriales	1117|Cyanobacteria	S	Family of unknown function (DUF5335)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5335
SYD2_k127_2559584_2	886293.Sinac_3851	2.907e-84	286.0	COG1926@1|root,COG1926@2|Bacteria,2J36S@203682|Planctomycetes	203682|Planctomycetes	F	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
SYD2_k127_2559584_5	1173024.KI912148_gene3333	9.441e-80	275.0	COG0412@1|root,COG0412@2|Bacteria,1G1CY@1117|Cyanobacteria,1JJI9@1189|Stigonemataceae	1117|Cyanobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SYD2_k127_265_10	1267534.KB906757_gene956	3.984e-123	420.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase,Trans_reg_C,WD40
SYD2_k127_265_9	204669.Acid345_1052	6.204e-129	432.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SYD2_k127_265_5	1267534.KB906760_gene1549	1.758e-206	672.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SYD2_k127_265_3	1267534.KB906760_gene1549	7.161e-208	683.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SYD2_k127_265_2	1267533.KB906735_gene4448	7.478e-218	709.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y2YM@57723|Acidobacteria,2JKAC@204432|Acidobacteriia	204432|Acidobacteriia	K	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_17
SYD2_k127_265_12	234267.Acid_5254	7.241e-95	322.0	COG3608@1|root,COG3608@2|Bacteria,3Y8T6@57723|Acidobacteria	2|Bacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
SYD2_k127_265_0	1379270.AUXF01000003_gene3587	0.0	1373.0	COG4447@1|root,COG4447@2|Bacteria,1ZSRM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SYD2_k127_265_29	1266909.AUAG01000019_gene443	2.336e-13	75.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WVVT@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
SYD2_k127_265_26	41875.XP_007511676.1	8.544e-23	110.0	28M8C@1|root,2S5PV@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_265_23	234267.Acid_0996	1.852e-38	151.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,TehB
SYD2_k127_265_30	234267.Acid_7410	4.96e-07	55.0	2EE2F@1|root,337X5@2|Bacteria,3Y5GQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_265_11	646529.Desaci_3047	1.456e-103	346.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SYD2_k127_265_24	646529.Desaci_3048	3.319e-25	109.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,24N57@186801|Clostridia,26324@186807|Peptococcaceae	186801|Clostridia	K	PFAM Bacterial regulatory proteins, gntR family	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SYD2_k127_265_18	1191523.MROS_1301	2.022e-63	222.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SYD2_k127_265_1	1382359.JIAL01000001_gene2069	5.895e-230	722.0	COG0055@1|root,COG0055@2|Bacteria,3Y2PU@57723|Acidobacteria,2JIDM@204432|Acidobacteriia	204432|Acidobacteriia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SYD2_k127_265_25	690850.Desaf_1585	2.465e-24	107.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2WPVK@28221|Deltaproteobacteria,2MBW9@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
SYD2_k127_265_14	321332.CYB_0455	2.928e-72	252.0	COG0854@1|root,COG0854@2|Bacteria,1G0QW@1117|Cyanobacteria,1GZKF@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
SYD2_k127_265_19	926566.Terro_0936	4.546e-59	216.0	COG1215@1|root,COG1215@2|Bacteria,3Y3PN@57723|Acidobacteria,2JHSE@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SYD2_k127_265_13	903818.KI912268_gene2333	3.699e-90	319.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SYD2_k127_265_4	861299.J421_1510	1.017e-207	659.0	COG0154@1|root,COG0154@2|Bacteria,1ZT8R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SYD2_k127_265_22	869210.Marky_0290	1.437e-38	150.0	COG0801@1|root,COG0801@2|Bacteria,1WJU9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SYD2_k127_265_27	222534.KB893717_gene2138	9.026e-21	106.0	COG2865@1|root,COG2865@2|Bacteria,2GZ30@201174|Actinobacteria,4ETCG@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
SYD2_k127_265_17	767817.Desgi_1848	1.501e-64	235.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,260VP@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SYD2_k127_265_21	331678.Cphamn1_1960	7.738e-44	163.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	23S_rRNA_IVP
SYD2_k127_265_16	234267.Acid_1840	1.103e-67	239.0	COG1235@1|root,COG1235@2|Bacteria,3Y40S@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
SYD2_k127_265_28	485915.Dret_2406	1.513e-13	80.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2MCVH@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
SYD2_k127_265_15	555079.Toce_0103	1.766e-71	250.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,42FE4@68295|Thermoanaerobacterales	186801|Clostridia	S	TIGRFAM MazG family protein	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
SYD2_k127_265_8	204669.Acid345_0704	3.593e-143	463.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SYD2_k127_265_6	1304275.C41B8_18181	8.955e-194	618.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_3,Fer4_7
SYD2_k127_265_20	401053.AciPR4_3251	6.889e-46	171.0	COG2318@1|root,COG2318@2|Bacteria,3Y81K@57723|Acidobacteria,2JN5E@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SYD2_k127_265_7	525909.Afer_1020	2.491e-155	494.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4CNGZ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SYD2_k127_2675776_6	1267533.KB906740_gene287	8.226e-05	45.0	COG0457@1|root,COG0823@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	DUF4214,SBBP,TPR_19
SYD2_k127_2675776_4	251221.35214700	5.155e-111	383.0	COG4166@1|root,COG4166@2|Bacteria,1GR16@1117|Cyanobacteria	1117|Cyanobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SYD2_k127_2675776_5	1267535.KB906767_gene277	2.449e-63	220.0	2DB97@1|root,33TRP@2|Bacteria,3Y7NY@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2675776_1	1379698.RBG1_1C00001G1167	1.039e-129	423.0	COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria	2|Bacteria	O	smart pdz dhr glgf	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SYD2_k127_2675776_3	317936.Nos7107_0111	4.629e-115	378.0	28IG1@1|root,2Z8HJ@2|Bacteria,1G0EA@1117|Cyanobacteria,1HMR5@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2675776_2	706587.Desti_1031	5.633e-119	396.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585,ko:K07799	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00646,M00647,M00648,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1,8.A.1.6	-	-	HlyD_D23
SYD2_k127_2675776_0	706587.Desti_1032	0.0	1542.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
SYD2_k127_2689207_2	1448389.BAVQ01000001_gene2847	1.105e-17	84.0	COG1917@1|root,COG1917@2|Bacteria,2IDTH@201174|Actinobacteria	201174|Actinobacteria	S	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
SYD2_k127_2689207_1	1267533.KB906733_gene3362	6.399e-95	332.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y7E7@57723|Acidobacteria,2JKGS@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SYD2_k127_2689207_0	204669.Acid345_1455	2.935e-136	454.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SYD2_k127_2737075_7	1499967.BAYZ01000025_gene303	2.538e-07	57.0	COG1120@1|root,COG1120@2|Bacteria	2|Bacteria	HP	ATPase activity	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SYD2_k127_2737075_1	1128421.JAGA01000001_gene2202	5.366e-119	394.0	COG2211@1|root,COG2211@2|Bacteria,2NPEZ@2323|unclassified Bacteria	2|Bacteria	G	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
SYD2_k127_2737075_5	234267.Acid_1489	2.106e-26	121.0	COG0501@1|root,COG0501@2|Bacteria,3Y8SC@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the peptidase M48B family	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2737075_6	234267.Acid_1488	1.391e-23	106.0	COG3682@1|root,COG3682@2|Bacteria,3Y8QA@57723|Acidobacteria	57723|Acidobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SYD2_k127_2737075_2	278963.ATWD01000002_gene422	9.076e-106	350.0	COG2107@1|root,COG2107@2|Bacteria,3Y31U@57723|Acidobacteria,2JIDE@204432|Acidobacteriia	204432|Acidobacteriia	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SYD2_k127_2737075_0	926566.Terro_1502	5.539e-122	401.0	COG1060@1|root,COG1060@2|Bacteria,3Y331@57723|Acidobacteria,2JITB@204432|Acidobacteriia	204432|Acidobacteriia	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SYD2_k127_2737075_3	1198114.AciX9_2640	2.153e-84	288.0	COG0382@1|root,COG0382@2|Bacteria,3Y3CW@57723|Acidobacteria,2JIHD@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM UbiA prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SYD2_k127_2737075_4	1157490.EL26_08735	6.942e-52	190.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,4HFZX@91061|Bacilli,2789X@186823|Alicyclobacillaceae	91061|Bacilli	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
SYD2_k127_2767941_0	760568.Desku_2097	1.815e-124	409.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia,265TC@186807|Peptococcaceae	186801|Clostridia	M	Domain of unknown function (DUF1972)	-	-	-	ko:K12996	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SYD2_k127_2767941_1	234267.Acid_6231	1.095e-78	277.0	COG0438@1|root,COG0438@2|Bacteria,3Y58K@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SYD2_k127_2767941_2	1267535.KB906767_gene3059	4.863e-41	155.0	COG0335@1|root,COG0335@2|Bacteria,3Y4P6@57723|Acidobacteria,2JJ9V@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SYD2_k127_2767941_3	391165.GbCGDNIH1_1683	6.106e-36	138.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2TSIZ@28211|Alphaproteobacteria,2JQRF@204441|Rhodospirillales	204441|Rhodospirillales	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SYD2_k127_2845585_1	204669.Acid345_3936	3.105e-147	474.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SYD2_k127_2845585_2	204669.Acid345_4094	1.95e-89	302.0	COG1834@1|root,COG1834@2|Bacteria,3Y86C@57723|Acidobacteria	57723|Acidobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
SYD2_k127_2845585_7	1123261.AXDW01000023_gene3575	2.856e-16	85.0	COG1917@1|root,COG1917@2|Bacteria,1MZFB@1224|Proteobacteria,1SQCZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SYD2_k127_2845585_17	318996.AXAZ01000090_gene5783	8.968e-05	50.0	2AJCC@1|root,319XP@2|Bacteria,1NUQI@1224|Proteobacteria,2URSP@28211|Alphaproteobacteria,3K3ZM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2845585_10	991.IW20_12420	1.964e-13	74.0	COG1680@1|root,COG2976@1|root,COG1680@2|Bacteria,COG2976@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia,2NT82@237|Flavobacterium	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2,TPR_8
SYD2_k127_2845585_15	1713.JOFV01000006_gene2810	1.313e-07	63.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria,4F2UH@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2845585_0	395493.BegalDRAFT_1699	3.695e-301	934.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RR14@1236|Gammaproteobacteria,461Y7@72273|Thiotrichales	72273|Thiotrichales	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SYD2_k127_2845585_8	313612.L8106_22119	5.589e-15	76.0	COG3668@1|root,COG3668@2|Bacteria,1G8WD@1117|Cyanobacteria,1HDM2@1150|Oscillatoriales	1117|Cyanobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SYD2_k127_2845585_16	452637.Oter_1939	5.702e-06	51.0	2EGU9@1|root,33AKF@2|Bacteria,46YPZ@74201|Verrucomicrobia,3K9Z0@414999|Opitutae	414999|Opitutae	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
SYD2_k127_2845585_6	1267534.KB906754_gene2665	4.352e-54	195.0	2CB8S@1|root,30PE6@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
SYD2_k127_2845585_5	243090.RB27	4.254e-55	197.0	2E2RY@1|root,32XUA@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
SYD2_k127_2845585_4	861299.J421_4134	1.391e-57	204.0	COG2197@1|root,COG2197@2|Bacteria,1ZV09@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SYD2_k127_2845585_3	861299.J421_4153	2.87e-61	219.0	arCOG07533@1|root,2ZF5I@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SYD2_k127_2845585_11	1177154.Y5S_00394	2.678e-12	70.0	COG3668@1|root,COG3668@2|Bacteria,1N73M@1224|Proteobacteria,1SCB7@1236|Gammaproteobacteria,1XMW0@135619|Oceanospirillales	135619|Oceanospirillales	S	PFAM plasmid	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SYD2_k127_2845585_9	697282.Mettu_3520	1.293e-14	77.0	2DPTZ@1|root,333CW@2|Bacteria,1NE58@1224|Proteobacteria,1SG82@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2845585_12	1162668.LFE_0019	1.207e-11	69.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SYD2_k127_2845585_14	1500894.JQNN01000001_gene1115	7.12e-09	68.0	COG0596@1|root,COG0596@2|Bacteria,1P1S6@1224|Proteobacteria,2WGM8@28216|Betaproteobacteria,477MT@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SYD2_k127_287624_1	1121957.ATVL01000009_gene937	5.293e-48	178.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,47KDS@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase family M3	-	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SYD2_k127_287624_0	204669.Acid345_4231	9.201e-165	548.0	COG5009@1|root,COG5009@2|Bacteria,3Y31C@57723|Acidobacteria,2JHJY@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SYD2_k127_2899024_2	1184267.A11Q_1675	6.339e-174	557.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42MBF@68525|delta/epsilon subdivisions,2MSUI@213481|Bdellovibrionales,2WJQ2@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SYD2_k127_2899024_4	1270196.JCKI01000003_gene1800	9.833e-76	265.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1INPZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SYD2_k127_2899024_3	264462.Bd3447	2.565e-134	445.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2MSZP@213481|Bdellovibrionales,2WJ5V@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SYD2_k127_2899024_7	1184267.A11Q_1677	3.406e-28	125.0	COG0373@1|root,COG0373@2|Bacteria,1QS8F@1224|Proteobacteria,437H1@68525|delta/epsilon subdivisions,2MT7N@213481|Bdellovibrionales,2X2QD@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Glutamyl-tRNAGlu reductase, N-terminal domain	-	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,Shikimate_DH
SYD2_k127_2899024_1	661478.OP10G_1529	7.208e-208	665.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SYD2_k127_2899024_0	234267.Acid_7295	2.307e-224	714.0	COG0441@1|root,COG0441@2|Bacteria,3Y2V0@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SYD2_k127_2899024_5	641491.DND132_1096	6.256e-49	178.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,42RHA@68525|delta/epsilon subdivisions,2WNQW@28221|Deltaproteobacteria,2M933@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SYD2_k127_2899024_9	713586.KB900536_gene355	1.854e-08	57.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,1WWSS@135613|Chromatiales	135613|Chromatiales	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SYD2_k127_2899024_8	903818.KI912268_gene2462	1.616e-19	89.0	COG0291@1|root,COG0291@2|Bacteria,3Y5US@57723|Acidobacteria	57723|Acidobacteria	J	Ribosomal protein L35	-	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SYD2_k127_2899024_6	240015.ACP_2248	1.906e-44	165.0	COG0292@1|root,COG0292@2|Bacteria,3Y4SW@57723|Acidobacteria,2JJJ2@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SYD2_k127_290125_7	99598.Cal7507_6086	8.148e-38	143.0	COG3548@1|root,COG3548@2|Bacteria,1GKP7@1117|Cyanobacteria,1HRK3@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SYD2_k127_290125_6	1340493.JNIF01000003_gene4251	2.034e-40	164.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	FHA,VWA,VWA_2
SYD2_k127_290125_3	1380408.AVGH01000040_gene2968	7.525e-79	273.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,21WRM@150247|Anoxybacillus	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	iYO844.BSU39420	DeoC
SYD2_k127_290125_5	234267.Acid_2204	1.01e-42	166.0	COG0698@1|root,COG0698@2|Bacteria	2|Bacteria	G	galactose-6-phosphate isomerase activity	upp	-	2.4.2.9,5.3.1.6	ko:K00761,ko:K01808	ko00030,ko00051,ko00240,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00240,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R00966,R01056,R09030	RC00063,RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB,UPRTase
SYD2_k127_290125_2	1227739.Hsw_3185	2.688e-82	284.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,47JR3@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
SYD2_k127_290125_9	984262.SGRA_4225	1.207e-22	108.0	COG0737@1|root,COG0737@2|Bacteria,4NR6D@976|Bacteroidetes,1ITBW@117747|Sphingobacteriia	976|Bacteroidetes	F	5'-nucleotidase	ushA	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C
SYD2_k127_290125_4	696281.Desru_1270	4.847e-65	227.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,261JF@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SYD2_k127_290125_1	1267534.KB906754_gene3465	6.594e-100	334.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria,2JM9F@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SYD2_k127_290125_0	756499.Desde_2885	4.055e-143	464.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,260HR@186807|Peptococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
SYD2_k127_290125_10	1089553.Tph_c01960	1.057e-15	79.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SYD2_k127_290125_11	927704.SELR_11000	4.698e-11	65.0	COG1724@1|root,COG1724@2|Bacteria,1VKIY@1239|Firmicutes,4H69A@909932|Negativicutes	909932|Negativicutes	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SYD2_k127_290125_8	926566.Terro_3228	1.521e-27	127.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SYD2_k127_2919270_1	94624.Bpet4648	3.147e-45	167.0	COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria,2VK7I@28216|Betaproteobacteria,3T3TM@506|Alcaligenaceae	28216|Betaproteobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SYD2_k127_2919270_0	1405.DJ92_5164	5.607e-56	206.0	COG1670@1|root,COG1670@2|Bacteria,1V5WS@1239|Firmicutes,4HH37@91061|Bacilli,1ZEZG@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SYD2_k127_2919270_3	1499968.TCA2_3253	1.889e-09	65.0	COG2318@1|root,COG2318@2|Bacteria,1VB99@1239|Firmicutes,4HNES@91061|Bacilli,26ZFK@186822|Paenibacillaceae	91061|Bacilli	S	DinB family	yisT	-	-	-	-	-	-	-	-	-	-	-	DinB
SYD2_k127_2919270_2	1267535.KB906767_gene4818	6.166e-44	163.0	COG3801@1|root,COG3801@2|Bacteria,3Y89M@57723|Acidobacteria	57723|Acidobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SYD2_k127_2927380_17	1267535.KB906767_gene3962	2.475e-29	130.0	COG3209@1|root,COG3209@2|Bacteria,3Y7FC@57723|Acidobacteria,2JKK9@204432|Acidobacteriia	204432|Acidobacteriia	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
SYD2_k127_2927380_21	1192034.CAP_4525	7.101e-21	105.0	COG3409@1|root,COG3770@1|root,COG3409@2|Bacteria,COG3770@2|Bacteria	2|Bacteria	M	serine-type endopeptidase activity	-	-	3.5.1.104	ko:K07261,ko:K17733,ko:K22278	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,Peptidase_M74
SYD2_k127_2927380_22	1173029.JH980292_gene614	7.134e-18	94.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	META,YscW
SYD2_k127_2927380_18	1340493.JNIF01000003_gene3378	9.098e-27	114.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	tccC1	-	-	ko:K11021	-	-	-	-	ko00000,ko02042	-	-	-	-
SYD2_k127_2927380_13	909663.KI867150_gene2187	4.612e-50	188.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,42MBJ@68525|delta/epsilon subdivisions,2WNWX@28221|Deltaproteobacteria,2MQKM@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
SYD2_k127_2927380_12	1121920.AUAU01000001_gene2169	5.708e-56	204.0	2919Q@1|root,32TZW@2|Bacteria,3Y5IU@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2927380_0	861299.J421_2166	3.812e-291	914.0	COG1529@1|root,COG1529@2|Bacteria,1ZSUN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
SYD2_k127_2927380_9	1121920.AUAU01000002_gene1985	1.711e-64	224.0	COG2080@1|root,COG2080@2|Bacteria,3Y4U1@57723|Acidobacteria	57723|Acidobacteria	C	2Fe-2S -binding domain protein	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SYD2_k127_2927380_5	234267.Acid_1969	4.444e-126	416.0	COG1228@1|root,COG1228@2|Bacteria,3Y47R@57723|Acidobacteria	2|Bacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SYD2_k127_2927380_15	278963.ATWD01000002_gene823	1.259e-44	189.0	COG0457@1|root,COG0457@2|Bacteria,3Y59I@57723|Acidobacteria,2JJNP@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2927380_8	1122604.JONR01000025_gene4602	3.701e-75	289.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SHX7@1236|Gammaproteobacteria,1X4MN@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SYD2_k127_2927380_3	234267.Acid_7916	2.843e-138	493.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	234267.Acid_7916|-	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SYD2_k127_2927380_25	406124.ACPC01000009_gene1404	7.955e-10	69.0	COG0457@1|root,COG0457@2|Bacteria,1V04B@1239|Firmicutes,4HBW4@91061|Bacilli,1ZF2U@1386|Bacillus	91061|Bacilli	S	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SYD2_k127_2927380_19	483219.LILAB_07800	1.418e-25	119.0	COG4219@1|root,COG4219@2|Bacteria,1P0K4@1224|Proteobacteria	1224|Proteobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2927380_16	1380394.JADL01000002_gene1628	2.641e-34	133.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2UC5C@28211|Alphaproteobacteria,2JXIK@204441|Rhodospirillales	204441|Rhodospirillales	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SYD2_k127_2927380_4	204669.Acid345_1712	9.331e-131	432.0	COG1680@1|root,COG1680@2|Bacteria,3Y3WB@57723|Acidobacteria,2JJDH@204432|Acidobacteriia	204432|Acidobacteriia	V	PFAM beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SYD2_k127_2927380_2	234267.Acid_7338	8.314e-167	538.0	COG1228@1|root,COG1228@2|Bacteria,3Y39J@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SYD2_k127_2927380_23	329726.AM1_6035	4.141e-15	81.0	2F8VD@1|root,3417B@2|Bacteria,1GEHW@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2927380_6	240292.Ava_1800	8.081e-101	336.0	COG1028@1|root,COG1028@2|Bacteria,1GDEA@1117|Cyanobacteria,1HRGV@1161|Nostocales	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SYD2_k127_2927380_11	1288826.MSNKSG1_02083	2.327e-60	214.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,1S427@1236|Gammaproteobacteria,467TN@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SYD2_k127_2927380_24	404589.Anae109_0692	1.879e-13	75.0	COG2018@1|root,COG2018@2|Bacteria,1NG1T@1224|Proteobacteria,42VP4@68525|delta/epsilon subdivisions,2WS9A@28221|Deltaproteobacteria,2YVP4@29|Myxococcales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2927380_10	1047013.AQSP01000124_gene2676	1.09e-63	242.0	COG4796@1|root,COG4796@2|Bacteria,2NPEQ@2323|unclassified Bacteria	2|Bacteria	U	Secretin and TonB N terminus short domain	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
SYD2_k127_2927380_27	1167006.UWK_00797	2.232e-07	60.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,42S1V@68525|delta/epsilon subdivisions,2WNDR@28221|Deltaproteobacteria,2MJVB@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM Pilus assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
SYD2_k127_2927380_7	204669.Acid345_1469	2.277e-89	312.0	COG4972@1|root,COG4972@2|Bacteria,3Y804@57723|Acidobacteria	57723|Acidobacteria	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SYD2_k127_2927380_14	1121468.AUBR01000001_gene469	7.703e-46	174.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,42GAD@68295|Thermoanaerobacterales	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SYD2_k127_2927380_20	1267535.KB906767_gene3018	1.027e-22	103.0	COG0776@1|root,COG0776@2|Bacteria,3Y5E1@57723|Acidobacteria,2JJN0@204432|Acidobacteriia	204432|Acidobacteriia	L	Bacterial DNA-binding protein	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SYD2_k127_2927380_1	234267.Acid_3518	7.42e-288	914.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
SYD2_k127_2950771_2	639030.JHVA01000001_gene1462	1.666e-130	427.0	COG0482@1|root,COG0482@2|Bacteria,3Y2JX@57723|Acidobacteria,2JHKV@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SYD2_k127_2950771_3	1379698.RBG1_1C00001G0370	2.749e-125	422.0	COG0616@1|root,COG0616@2|Bacteria,2NNKU@2323|unclassified Bacteria	2|Bacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SYD2_k127_2950771_11	1267535.KB906767_gene5350	9.777e-38	159.0	COG1538@1|root,COG1538@2|Bacteria,3Y3PX@57723|Acidobacteria,2JHUZ@204432|Acidobacteriia	204432|Acidobacteriia	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SYD2_k127_2950771_9	240015.ACP_0735	3.972e-42	173.0	COG0845@1|root,COG0845@2|Bacteria,3Y3C9@57723|Acidobacteria,2JIN9@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
SYD2_k127_2950771_0	1267533.KB906741_gene557	9.106e-287	914.0	COG0841@1|root,COG0841@2|Bacteria,3Y3F4@57723|Acidobacteria,2JIHS@204432|Acidobacteriia	204432|Acidobacteriia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SYD2_k127_2950771_4	682795.AciX8_3593	2.232e-108	361.0	COG3391@1|root,COG3391@2|Bacteria,3Y48Y@57723|Acidobacteria,2JJ87@204432|Acidobacteriia	204432|Acidobacteriia	S	YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2950771_10	234267.Acid_2286	6.2e-42	166.0	COG0671@1|root,COG0671@2|Bacteria,3Y5F0@57723|Acidobacteria	57723|Acidobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SYD2_k127_2950771_12	1004785.AMBLS11_10285	6.715e-26	111.0	2E363@1|root,32Y5Y@2|Bacteria,1P1I8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2950771_1	555079.Toce_0176	2.236e-157	507.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,42EYY@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SYD2_k127_2950771_5	497964.CfE428DRAFT_4748	7.177e-89	303.0	COG1208@1|root,COG1208@2|Bacteria,46V3X@74201|Verrucomicrobia	74201|Verrucomicrobia	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SYD2_k127_2950771_6	1191523.MROS_0663	1.984e-81	282.0	COG3358@1|root,COG3358@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SYD2_k127_2950771_8	945713.IALB_0606	1.848e-46	179.0	COG0457@1|root,COG0457@2|Bacteria	945713.IALB_0606|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2950771_7	204669.Acid345_4377	8.919e-68	243.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria,2JM41@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SYD2_k127_2988815_2	1444306.JFZC01000055_gene705	1.886e-23	107.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli,26NUZ@186821|Sporolactobacillaceae	91061|Bacilli	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SYD2_k127_2988815_1	521098.Aaci_1785	3.403e-42	163.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,279UX@186823|Alicyclobacillaceae	91061|Bacilli	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SYD2_k127_2988815_3	316274.Haur_2172	1.145e-16	91.0	2CPJB@1|root,32SJ9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2988815_0	215803.DB30_2176	6.751e-135	436.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2YUJ1@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SYD2_k127_2999101_0	575540.Isop_3282	8.813e-228	723.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SYD2_k127_2999101_6	379066.GAU_0167	9.754e-22	100.0	COG2924@1|root,COG2924@2|Bacteria,1ZTWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
SYD2_k127_2999101_4	1283299.AUKG01000002_gene3714	1.777e-33	134.0	COG1225@1|root,COG1225@2|Bacteria,2IJVV@201174|Actinobacteria,4CRY9@84995|Rubrobacteria	84995|Rubrobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SYD2_k127_2999101_1	1379698.RBG1_1C00001G0804	2.412e-137	448.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SYD2_k127_2999101_5	204669.Acid345_4762	1.722e-28	132.0	28N30@1|root,2ZB8S@2|Bacteria,3Y2XH@57723|Acidobacteria,2JI3V@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_2999101_7	32057.KB217478_gene5311	9.377e-19	89.0	COG3668@1|root,COG3668@2|Bacteria,1G8WD@1117|Cyanobacteria,1HNXJ@1161|Nostocales	1117|Cyanobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SYD2_k127_2999101_8	1304275.C41B8_10495	2.027e-09	61.0	2DRB5@1|root,33B20@2|Bacteria,1NIFF@1224|Proteobacteria,1SGF4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
SYD2_k127_2999101_3	330214.NIDE3564	4.988e-87	325.0	COG4548@1|root,COG4548@2|Bacteria	2|Bacteria	P	von Willebrand factor (vWF) type A domain	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA,VWA_2
SYD2_k127_2999101_2	192952.MM_2988	2.569e-114	374.0	COG0714@1|root,arCOG00441@2157|Archaea,2Y6X0@28890|Euryarchaeota,2NAEY@224756|Methanomicrobia	224756|Methanomicrobia	S	CbbQ/NirQ/NorQ C-terminal	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
SYD2_k127_3025906_6	509191.AEDB02000103_gene3772	1.341e-36	143.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,24HMI@186801|Clostridia,3WIS5@541000|Ruminococcaceae	186801|Clostridia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SYD2_k127_3025906_1	204669.Acid345_2125	2.507e-98	326.0	COG0217@1|root,COG0217@2|Bacteria,3Y2UW@57723|Acidobacteria,2JIJW@204432|Acidobacteriia	204432|Acidobacteriia	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SYD2_k127_3025906_0	1267533.KB906735_gene4448	8.778e-200	659.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y2YM@57723|Acidobacteria,2JKAC@204432|Acidobacteriia	204432|Acidobacteriia	K	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_17
SYD2_k127_3025906_7	269799.Gmet_1164	1.46e-18	89.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,42VE5@68525|delta/epsilon subdivisions,2WR8T@28221|Deltaproteobacteria,43VHW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SYD2_k127_3025906_8	316274.Haur_3842	3.389e-10	69.0	COG0762@1|root,COG0762@2|Bacteria,2G9QH@200795|Chloroflexi,3760D@32061|Chloroflexia	32061|Chloroflexia	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SYD2_k127_3025906_2	439235.Dalk_0394	1.063e-61	220.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria,2MJ9P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SYD2_k127_3025906_4	746697.Aeqsu_0542	7.936e-54	203.0	COG0492@1|root,COG0492@2|Bacteria,4NDVS@976|Bacteroidetes,1HXB3@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM Pyridine nucleotide-disulphide oxidoreductase	ypdA	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
SYD2_k127_3025906_3	330214.NIDE2777	1.371e-58	214.0	COG0384@1|root,COG0384@2|Bacteria	2|Bacteria	S	isomerase activity	yddE	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
SYD2_k127_3025906_5	1267535.KB906767_gene2456	5.409e-51	187.0	COG1752@1|root,COG1752@2|Bacteria,3Y6DZ@57723|Acidobacteria,2JMMY@204432|Acidobacteriia	204432|Acidobacteriia	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SYD2_k127_3061471_2	215803.DB30_6786	1.249e-122	402.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,42UGV@68525|delta/epsilon subdivisions,2WR1G@28221|Deltaproteobacteria,2YUDE@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SYD2_k127_3061471_0	401053.AciPR4_0237	4.188e-179	575.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria,2JJ0K@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SYD2_k127_3061471_8	221288.JH992901_gene760	2.846e-27	117.0	2CKCH@1|root,331PP@2|Bacteria,1G6N7@1117|Cyanobacteria,1JJ4W@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3061471_9	1382359.JIAL01000001_gene2110	1.653e-16	81.0	COG0268@1|root,COG0268@2|Bacteria,3Y5CZ@57723|Acidobacteria,2JJS9@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SYD2_k127_3061471_5	1340493.JNIF01000004_gene944	4.369e-54	208.0	COG4783@1|root,COG4783@2|Bacteria,3Y6B5@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SYD2_k127_3061471_3	204669.Acid345_2517	1.495e-63	226.0	COG3809@1|root,COG3809@2|Bacteria,3Y803@57723|Acidobacteria	57723|Acidobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zf-TFIIB
SYD2_k127_3061471_1	1210884.HG799462_gene8074	1.16e-134	435.0	COG1090@1|root,COG1090@2|Bacteria,2IYWK@203682|Planctomycetes	203682|Planctomycetes	S	nucleoside-diphosphate sugar epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SYD2_k127_3061471_4	1394178.AWOO02000007_gene3118	5.79e-63	224.0	COG1309@1|root,COG1309@2|Bacteria,2GJES@201174|Actinobacteria,4EIGA@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SYD2_k127_3061471_7	497964.CfE428DRAFT_2364	1.18e-27	116.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
SYD2_k127_3061471_6	497964.CfE428DRAFT_2363	1.608e-49	181.0	2DN6W@1|root,32UIF@2|Bacteria,46WNT@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3068080_6	357808.RoseRS_2094	3.062e-128	425.0	COG0318@1|root,COG0318@2|Bacteria,2G7VC@200795|Chloroflexi	200795|Chloroflexi	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SYD2_k127_3068080_39	66875.JODY01000041_gene1912	3.107e-23	110.0	COG0672@1|root,COG0672@2|Bacteria,2GJ22@201174|Actinobacteria	201174|Actinobacteria	P	Iron permease FTR1	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
SYD2_k127_3068080_32	864702.OsccyDRAFT_2960	4.05e-37	145.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1G3FF@1117|Cyanobacteria,1H77D@1150|Oscillatoriales	1117|Cyanobacteria	T	Serine phosphatase RsbU regulator of sigma subunit	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,GAF_3,Response_reg,SpoIIE
SYD2_k127_3068080_21	1144319.PMI16_02546	6.798e-73	263.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_9,Response_reg
SYD2_k127_3068080_44	671143.DAMO_1779	5.703e-15	79.0	COG0784@1|root,COG2199@1|root,COG2204@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2204@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,2NP93@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K21025	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SYD2_k127_3068080_31	1173025.GEI7407_3614	4.156e-38	166.0	COG2202@1|root,COG2203@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9
SYD2_k127_3068080_22	330214.NIDE1491	4.554e-70	271.0	COG0745@1|root,COG2202@1|root,COG3829@1|root,COG4585@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,3J12P@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA_3,PAS_9
SYD2_k127_3068080_25	1175306.GWL_20380	1.756e-59	214.0	COG2197@1|root,COG2197@2|Bacteria,1RH8D@1224|Proteobacteria,2WEH4@28216|Betaproteobacteria,4778U@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	PFAM Response regulator receiver domain, Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SYD2_k127_3068080_46	715226.ABI_13320	1.834e-13	76.0	COG0745@1|root,COG0745@2|Bacteria	715226.ABI_13320|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3068080_7	1210884.HG799465_gene12259	2.001e-127	439.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SYD2_k127_3068080_45	234267.Acid_7240	5.881e-14	76.0	COG0542@1|root,COG2204@1|root,COG0542@2|Bacteria,COG2204@2|Bacteria,3Y6T8@57723|Acidobacteria	57723|Acidobacteria	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small,Response_reg
SYD2_k127_3068080_16	1210884.HG799464_gene10556	2.81e-91	324.0	COG3852@1|root,COG3852@2|Bacteria,2J4WN@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
SYD2_k127_3068080_9	1123508.JH636442_gene4246	9.514e-124	441.0	COG4251@1|root,COG4251@2|Bacteria,2IZ70@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
SYD2_k127_3068080_1	880073.Calab_1764	3.197e-178	606.0	COG4191@1|root,COG4191@2|Bacteria,2NP93@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SYD2_k127_3068080_10	1157490.EL26_19350	5.751e-119	404.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,2798R@186823|Alicyclobacillaceae	91061|Bacilli	T	Putative diguanylate phosphodiesterase	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,HAMP,MHYT,PAS,PAS_3,PAS_4,PAS_9
SYD2_k127_3068080_12	1144275.COCOR_01123	4.734e-104	359.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	nla28	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SYD2_k127_3068080_48	383372.Rcas_2278	1.332e-10	66.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Pkinase
SYD2_k127_3068080_52	1454202.PPBDW_140160___1	1.321e-05	49.0	2DT0U@1|root,33I6V@2|Bacteria,1NMHR@1224|Proteobacteria,1SGK7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3068080_24	1041930.Mtc_1015	5.344e-60	226.0	COG0457@1|root,arCOG03042@1|root,arCOG03032@2157|Archaea,arCOG03042@2157|Archaea,2Y7M7@28890|Euryarchaeota,2NBM0@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
SYD2_k127_3068080_17	237368.SCABRO_02433	5.134e-91	309.0	COG0123@1|root,COG0123@2|Bacteria,2IXK9@203682|Planctomycetes	203682|Planctomycetes	BQ	including yeast histone deacetylase and acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SYD2_k127_3068080_2	1318628.MARLIPOL_07224	1.382e-173	597.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria,465V0@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235,RHS,RHS_repeat
SYD2_k127_3068080_50	1408254.T458_11550	3.671e-10	71.0	COG0338@1|root,COG3392@1|root,COG0338@2|Bacteria,COG3392@2|Bacteria,1TRDX@1239|Firmicutes,4HDFS@91061|Bacilli,26R7M@186822|Paenibacillaceae	91061|Bacilli	L	Site-specific DNA-methyltransferase (adenine-specific)	dpnM	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
SYD2_k127_3068080_33	1283299.AUKG01000005_gene99	1.132e-33	139.0	COG3437@1|root,COG3437@2|Bacteria,2I49F@201174|Actinobacteria	2|Bacteria	T	HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5
SYD2_k127_3068080_51	59196.RICGR_1123	4.32e-08	66.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,1JCER@118969|Legionellales	118969|Legionellales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SYD2_k127_3068080_47	378806.STAUR_4794	3.191e-12	79.0	COG0745@1|root,COG0745@2|Bacteria,1Q3SH@1224|Proteobacteria,439KM@68525|delta/epsilon subdivisions,2X4XF@28221|Deltaproteobacteria,2YZSR@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
SYD2_k127_3068080_18	316067.Geob_0753	4.745e-89	304.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,43U9P@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SYD2_k127_3068080_37	234267.Acid_3399	3.413e-26	121.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SYD2_k127_3068080_3	1267535.KB906767_gene4427	1.746e-151	491.0	COG1206@1|root,COG1206@2|Bacteria,3Y2KD@57723|Acidobacteria,2JIGU@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
SYD2_k127_3068080_11	1242864.D187_001445	3.815e-111	366.0	COG5285@1|root,COG5285@2|Bacteria,1Q78R@1224|Proteobacteria,438ZF@68525|delta/epsilon subdivisions,2X44Q@28221|Deltaproteobacteria,2YY90@29|Myxococcales	28221|Deltaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	1.14.11.18	ko:K00477	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	PhyH
SYD2_k127_3068080_20	1123261.AXDW01000003_gene1978	4.274e-78	269.0	COG5526@1|root,COG5526@2|Bacteria,1RA0A@1224|Proteobacteria,1S4KY@1236|Gammaproteobacteria,1X9U5@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3068080_0	204669.Acid345_0997	9.457e-272	849.0	COG0449@1|root,COG0449@2|Bacteria,3Y2NE@57723|Acidobacteria,2JI69@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SYD2_k127_3068080_8	498761.HM1_0728	6.113e-124	412.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
SYD2_k127_3068080_15	1382359.JIAL01000001_gene1385	1.389e-91	313.0	COG0391@1|root,COG0391@2|Bacteria,3Y3ZE@57723|Acidobacteria,2JITK@204432|Acidobacteriia	204432|Acidobacteriia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SYD2_k127_3068080_53	290397.Adeh_0307	0.0006143	51.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria	1224|Proteobacteria	S	major pilin protein fima	MA20_16755	-	-	-	-	-	-	-	-	-	-	-	DUF1028
SYD2_k127_3068080_30	1121918.ARWE01000001_gene254	2.812e-43	162.0	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,43T83@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Roadblock LC7 family protein	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
SYD2_k127_3068080_14	204669.Acid345_0708	7.135e-94	310.0	COG1100@1|root,COG1100@2|Bacteria,3Y7CQ@57723|Acidobacteria	57723|Acidobacteria	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
SYD2_k127_3068080_43	410359.Pcal_0958	1.626e-15	83.0	COG0456@1|root,arCOG00833@2157|Archaea,2XR31@28889|Crenarchaeota	28889|Crenarchaeota	K	TIGRFAM ribosomal-protein-alanine acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SYD2_k127_3068080_13	1378168.N510_02559	2.11e-103	349.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes	1239|Firmicutes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SYD2_k127_3068080_42	639030.JHVA01000001_gene1198	2.547e-19	99.0	COG1295@1|root,COG1295@2|Bacteria,3Y3AJ@57723|Acidobacteria,2JIPS@204432|Acidobacteriia	204432|Acidobacteriia	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SYD2_k127_3068080_5	1485545.JQLW01000007_gene773	3.29e-135	439.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria	1224|Proteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SYD2_k127_3068080_28	234267.Acid_0956	6.778e-47	177.0	COG0632@1|root,COG0632@2|Bacteria,3Y4KI@57723|Acidobacteria	57723|Acidobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SYD2_k127_3068080_27	671143.DAMO_2689	8.515e-53	197.0	COG2344@1|root,COG2344@2|Bacteria,2NPI1@2323|unclassified Bacteria	2|Bacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SYD2_k127_3068080_26	697281.Mahau_1416	2.627e-58	212.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,42FQD@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Class II aldolase adducin	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SYD2_k127_3068080_34	1118057.CAGX01000059_gene328	2.619e-33	130.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,22HEI@1570339|Peptoniphilaceae	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
SYD2_k127_3068080_35	234267.Acid_0322	5.25e-31	124.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028,ko:K08697	-	-	-	-	ko00000	-	-	-	EutN_CcmL
SYD2_k127_3068080_40	234267.Acid_0323	9.444e-21	97.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
SYD2_k127_3068080_49	1449126.JQKL01000004_gene577	3.429e-10	65.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,269HK@186813|unclassified Clostridiales	186801|Clostridia	CQ	Ethanolamine utilisation protein EutN/carboxysome	ccmL	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
SYD2_k127_3068080_23	1379698.RBG1_1C00001G1352	1.143e-60	218.0	COG0428@1|root,COG0428@2|Bacteria,2NQ6J@2323|unclassified Bacteria	2|Bacteria	P	ZIP Zinc transporter	zupT	-	-	ko:K07238,ko:K11021,ko:K16267	-	-	-	-	ko00000,ko02000,ko02042	2.A.5.4.11,2.A.5.5	-	-	Zip
SYD2_k127_3068080_29	1382359.JIAL01000001_gene1949	1.923e-45	169.0	COG2001@1|root,COG2001@2|Bacteria,3Y4NF@57723|Acidobacteria,2JJA0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SYD2_k127_3068080_19	479434.Sthe_1998	2.156e-85	293.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,27XI5@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	-	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SYD2_k127_3068080_4	204669.Acid345_3635	2.192e-150	499.0	COG0768@1|root,COG0768@2|Bacteria,3Y2XX@57723|Acidobacteria,2JHPS@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein, dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
SYD2_k127_3068080_36	1382359.JIAL01000001_gene1955	2.076e-29	126.0	COG0770@1|root,COG0770@2|Bacteria,3Y3I2@57723|Acidobacteria,2JHW4@204432|Acidobacteriia	204432|Acidobacteriia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SYD2_k127_3113141_12	861299.J421_2137	5.356e-15	87.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
SYD2_k127_3113141_0	926550.CLDAP_36890	0.0	1730.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,2G5M1@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
SYD2_k127_3113141_2	926550.CLDAP_36880	2.214e-142	462.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SYD2_k127_3113141_4	204669.Acid345_0365	1.065e-65	232.0	COG2846@1|root,COG2846@2|Bacteria,3Y4SU@57723|Acidobacteria,2JMU3@204432|Acidobacteriia	204432|Acidobacteriia	D	Domain of Unknown function (DUF542)	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
SYD2_k127_3113141_5	234267.Acid_2934	1.79e-44	169.0	COG3945@1|root,COG3945@2|Bacteria,3Y5T8@57723|Acidobacteria	57723|Acidobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SYD2_k127_3113141_10	266117.Rxyl_1199	7.766e-18	90.0	COG2846@1|root,COG2846@2|Bacteria	2|Bacteria	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,Hemerythrin,NnrS
SYD2_k127_3113141_3	237368.SCABRO_00357	1.421e-83	300.0	COG2846@1|root,COG2846@2|Bacteria,2J2QY@203682|Planctomycetes	203682|Planctomycetes	D	Domain of unknown function (DUF1858)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
SYD2_k127_3113141_8	330214.NIDE3836	7.856e-23	107.0	COG2197@1|root,COG3290@1|root,COG2197@2|Bacteria,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	prhJ	-	-	ko:K06375	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	GerE,HATPase_c,PAS,PAS_4,PAS_8,PAS_9,Response_reg
SYD2_k127_3113141_9	323848.Nmul_A1774	2.92e-19	94.0	COG1959@1|root,COG1959@2|Bacteria,1RE3F@1224|Proteobacteria,2VRIR@28216|Betaproteobacteria,3736E@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SYD2_k127_3113141_6	1121920.AUAU01000008_gene1620	4.35e-44	179.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0328	Cytochrom_C,Cytochrome_CBB3
SYD2_k127_3113141_7	616991.JPOO01000003_gene1701	7.335e-42	154.0	COG5013@1|root,COG5013@2|Bacteria	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	narG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00370,ko:K17050	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685	Molybdopterin,Molydop_binding,Nitr_red_alph_N
SYD2_k127_3113141_1	1121920.AUAU01000008_gene1619	0.0	1124.0	COG5013@1|root,COG5013@2|Bacteria	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	narG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00370,ko:K17050	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685	Molybdopterin,Molydop_binding,Nitr_red_alph_N
SYD2_k127_3145130_2	204669.Acid345_3993	3.471e-32	141.0	COG2304@1|root,COG2304@2|Bacteria,3Y44P@57723|Acidobacteria,2JIT1@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SYD2_k127_3145130_0	533240.CRC_00827	2.693e-170	548.0	COG0448@1|root,COG0448@2|Bacteria,1G0IG@1117|Cyanobacteria,1HJRM@1161|Nostocales	1117|Cyanobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.agp,iSbBS512_1146.agp	NTP_transferase
SYD2_k127_3145130_1	99598.Cal7507_6086	6.413e-83	278.0	COG3548@1|root,COG3548@2|Bacteria,1GKP7@1117|Cyanobacteria,1HRK3@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SYD2_k127_3156645_4	861299.J421_6266	2.436e-184	587.0	COG2211@1|root,COG2211@2|Bacteria,1ZUJ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	MFS/sugar transport protein	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
SYD2_k127_3156645_9	118173.KB235910_gene5124	2.151e-32	136.0	COG4221@1|root,COG4221@2|Bacteria,1G1CB@1117|Cyanobacteria,1H8AJ@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SYD2_k127_3156645_1	861299.J421_6259	3.088e-213	680.0	COG0366@1|root,COG0366@2|Bacteria,1ZUGN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Cyclomaltodextrinase, N-terminal	-	-	3.2.1.135	ko:K21575	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_N
SYD2_k127_3156645_3	357808.RoseRS_1575	2.141e-191	610.0	COG1640@1|root,COG1640@2|Bacteria,2G668@200795|Chloroflexi,376Q1@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SYD2_k127_3156645_11	1122951.ATUE01000005_gene2108	1.109e-12	73.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
SYD2_k127_3156645_2	1267534.KB906754_gene3614	1.911e-198	642.0	COG0457@1|root,COG0457@2|Bacteria,3Y2Q7@57723|Acidobacteria,2JIH1@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,TPR_11,TPR_16,TPR_2,TPR_8
SYD2_k127_3156645_10	1267535.KB906767_gene3419	1.672e-25	122.0	COG0457@1|root,COG0457@2|Bacteria,3Y8SB@57723|Acidobacteria,2JNVT@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2
SYD2_k127_3156645_12	580340.Tlie_0365	1.702e-08	66.0	COG0457@1|root,COG0457@2|Bacteria	580340.Tlie_0365|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3156645_6	682795.AciX8_4279	7.071e-144	500.0	COG1629@1|root,COG4771@2|Bacteria,3Y3W1@57723|Acidobacteria,2JIP5@204432|Acidobacteriia	204432|Acidobacteriia	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SYD2_k127_3156645_8	234267.Acid_2678	1.153e-71	257.0	COG1940@1|root,COG1940@2|Bacteria,3Y3B2@57723|Acidobacteria	57723|Acidobacteria	GK	PFAM ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SYD2_k127_3156645_0	1267533.KB906733_gene3250	2.312e-214	681.0	COG0457@1|root,COG0457@2|Bacteria,3Y3VT@57723|Acidobacteria,2JHXZ@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
SYD2_k127_3156645_5	1267535.KB906767_gene3810	4.102e-183	593.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene3810|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3156645_7	1123508.JH636441_gene3044	2.27e-89	299.0	COG0388@1|root,COG0388@2|Bacteria,2IYR5@203682|Planctomycetes	203682|Planctomycetes	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SYD2_k127_3161326_5	1144275.COCOR_00961	4.636e-48	179.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,43BFP@68525|delta/epsilon subdivisions,2WMVT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SYD2_k127_3161326_1	215803.DB30_5845	1.78e-139	462.0	COG0402@1|root,COG0402@2|Bacteria,1MUFE@1224|Proteobacteria,43AI0@68525|delta/epsilon subdivisions,2X5Y7@28221|Deltaproteobacteria,2YURU@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	hutF	-	3.5.3.13	ko:K05603	ko00340,map00340	-	R02286	RC00682	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SYD2_k127_3161326_4	1123508.JH636440_gene2784	5.517e-56	201.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
SYD2_k127_3161326_6	709986.Deima_0819	5.663e-29	123.0	arCOG13559@1|root,33239@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
SYD2_k127_3161326_3	234267.Acid_7677	2.928e-57	205.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SYD2_k127_3161326_0	502025.Hoch_1577	5.117e-231	747.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SYD2_k127_3161326_2	1191523.MROS_0617	3.263e-108	360.0	COG1313@1|root,COG1313@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SYD2_k127_3161326_7	202954.BBNK01000021_gene3343	2.144e-14	87.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,3NM2T@468|Moraxellaceae	1236|Gammaproteobacteria	O	Peptidylprolyl isomerase	ppiD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SYD2_k127_3198147_5	204669.Acid345_0002	2.406e-68	242.0	COG0592@1|root,COG0592@2|Bacteria,3Y2WE@57723|Acidobacteria,2JI4X@204432|Acidobacteriia	204432|Acidobacteriia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SYD2_k127_3198147_2	635013.TherJR_0001	1.168e-120	402.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,260P2@186807|Peptococcaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SYD2_k127_3198147_6	1200792.AKYF01000001_gene4071	2.153e-67	241.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,26RXG@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the ParB family	spo0J	GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	HTH_3,KorB,ParBc
SYD2_k127_3198147_4	401526.TcarDRAFT_0906	5.28e-87	295.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4H331@909932|Negativicutes	909932|Negativicutes	D	Sporulation initiation inhibitor protein Soj	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SYD2_k127_3198147_0	240015.ACP_2349	3.389e-206	659.0	COG0445@1|root,COG0445@2|Bacteria,3Y3E4@57723|Acidobacteria,2JHP3@204432|Acidobacteriia	204432|Acidobacteriia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
SYD2_k127_3198147_3	204669.Acid345_4729	4.576e-114	383.0	COG0486@1|root,COG0486@2|Bacteria,3Y3QJ@57723|Acidobacteria,2JHNN@204432|Acidobacteriia	204432|Acidobacteriia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
SYD2_k127_3198147_7	309801.trd_1084	3.364e-19	93.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi,27XWI@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative single-stranded nucleic acids-binding domain	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,R3H
SYD2_k127_3198147_9	8010.XP_010864791.1	0.0004742	44.0	KOG1721@1|root,KOG1721@2759|Eukaryota,39ZJ2@33154|Opisthokonta,3BHUX@33208|Metazoa,3D5E6@33213|Bilateria,489JX@7711|Chordata,496K2@7742|Vertebrata,49R9X@7898|Actinopterygii	8010.XP_010864791.1|-	S	zinc finger protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3198147_8	45157.CMR299CT	2.224e-07	63.0	COG0457@1|root,KOG0548@2759|Eukaryota	2759|Eukaryota	J	positive regulation of catalytic activity in other organism involved in symbiotic interaction	STI1	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005794,GO:0005829,GO:0006457,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0008104,GO:0008150,GO:0009987,GO:0012505,GO:0015031,GO:0015833,GO:0016043,GO:0030234,GO:0030544,GO:0031072,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042030,GO:0042886,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0050790,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051879,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0072594,GO:0072655,GO:0097159,GO:0098772,GO:0101031,GO:1901363	-	ko:K09553	ko05020,map05020	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_1,TPR_11,TPR_12,TPR_16,TPR_2,TPR_8
SYD2_k127_3198147_1	401053.AciPR4_0212	3.831e-129	448.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Y@57723|Acidobacteria,2JKVG@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SYD2_k127_3231938_1	220341.16503194	5.961e-49	180.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,3ZJX4@590|Salmonella	1236|Gammaproteobacteria	E	AAA domain	yecC	GO:0000099,GO:0000101,GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0097159,GO:0097367,GO:0098656,GO:1901265,GO:1901363,GO:1901682,GO:1902475,GO:1903825,GO:1905039	3.6.3.21	ko:K02028,ko:K02029,ko:K10004,ko:K10010,ko:K10038	ko02010,ko02020,map02010,map02020	M00227,M00230,M00234,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.10,3.A.1.3.14,3.A.1.3.19,3.A.1.3.2,3.A.1.3.4	-	-	ABC_tran
SYD2_k127_3231938_0	645512.GCWU000246_00120	1.446e-100	348.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,3TAAM@508458|Synergistetes	508458|Synergistetes	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
SYD2_k127_3231938_3	204669.Acid345_2516	8.881e-07	55.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia	204432|Acidobacteriia	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SYD2_k127_3231938_2	28532.XP_010543807.1	3.198e-13	82.0	COG3914@1|root,KOG4626@2759|Eukaryota,37IV9@33090|Viridiplantae,3G9DX@35493|Streptophyta,3HPVG@3699|Brassicales	35493|Streptophyta	GOT	Est1 DNA/RNA binding domain	SPY	GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0007154,GO:0007165,GO:0008150,GO:0008194,GO:0008375,GO:0009719,GO:0009725,GO:0009735,GO:0009736,GO:0009739,GO:0009740,GO:0009755,GO:0009937,GO:0009938,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010476,GO:0010646,GO:0010648,GO:0016262,GO:0016740,GO:0016757,GO:0016758,GO:0019222,GO:0023051,GO:0023052,GO:0023057,GO:0031323,GO:0032870,GO:0033993,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071310,GO:0071368,GO:0071370,GO:0071396,GO:0071495,GO:0140096,GO:1901700,GO:1901701,GO:2000377	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_16,TPR_7,TPR_8
SYD2_k127_3240449_6	1265505.ATUG01000003_gene184	9.738e-18	89.0	COG1277@1|root,COG1277@2|Bacteria,1NCXV@1224|Proteobacteria,42VK2@68525|delta/epsilon subdivisions,2WRNT@28221|Deltaproteobacteria,2MPXF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SYD2_k127_3240449_5	204669.Acid345_1573	9.951e-33	142.0	COG0457@1|root,COG0457@2|Bacteria	204669.Acid345_1573|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3240449_1	391625.PPSIR1_04123	1.734e-82	284.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NSM@68525|delta/epsilon subdivisions,2WJXQ@28221|Deltaproteobacteria,2YXY8@29|Myxococcales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SYD2_k127_3240449_4	1385511.N783_03255	9.318e-37	145.0	COG0655@1|root,COG0655@2|Bacteria,1U9UK@1239|Firmicutes,4IK2B@91061|Bacilli,2YBPN@289201|Pontibacillus	91061|Bacilli	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SYD2_k127_3240449_2	335543.Sfum_3563	8.117e-69	246.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SYD2_k127_3240449_3	1192034.CAP_4020	2.621e-59	214.0	COG3361@1|root,COG3361@2|Bacteria,1Q2C9@1224|Proteobacteria,437YP@68525|delta/epsilon subdivisions,2X38K@28221|Deltaproteobacteria,2YUU6@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized conserved protein (COG2071)	-	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
SYD2_k127_3240449_7	1122599.AUGR01000002_gene3291	2.368e-08	61.0	2CDP6@1|root,32RY5@2|Bacteria,1N1TI@1224|Proteobacteria,1SC2T@1236|Gammaproteobacteria,1XKWR@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3240449_0	1340493.JNIF01000004_gene448	2.08e-109	359.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3IB@57723|Acidobacteria	57723|Acidobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SYD2_k127_3244889_5	404589.Anae109_1923	1.206e-51	183.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,42QS6@68525|delta/epsilon subdivisions,2WMPD@28221|Deltaproteobacteria,2YURE@29|Myxococcales	28221|Deltaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SYD2_k127_3244889_9	760011.Spico_1703	1.606e-24	104.0	COG0199@1|root,COG0199@2|Bacteria,2J8U1@203691|Spirochaetes	203691|Spirochaetes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SYD2_k127_3244889_6	1340493.JNIF01000003_gene3221	8.115e-48	174.0	COG0096@1|root,COG0096@2|Bacteria,3Y4IE@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SYD2_k127_3244889_4	1267533.KB906735_gene5115	4.674e-59	209.0	COG0097@1|root,COG0097@2|Bacteria,3Y496@57723|Acidobacteria,2JJ4H@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SYD2_k127_3244889_8	1340493.JNIF01000003_gene3223	8.971e-38	147.0	COG0256@1|root,COG0256@2|Bacteria,3Y5CH@57723|Acidobacteria	57723|Acidobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SYD2_k127_3244889_2	720554.Clocl_3878	1.701e-62	219.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3WICZ@541000|Ruminococcaceae	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SYD2_k127_3244889_10	639030.JHVA01000001_gene1536	6.654e-16	79.0	COG1841@1|root,COG1841@2|Bacteria,3Y5I2@57723|Acidobacteria,2JJZB@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SYD2_k127_3244889_7	273068.TTE2273	4.948e-45	168.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,42G84@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SYD2_k127_3244889_0	234267.Acid_5098	4.601e-153	497.0	COG0201@1|root,COG0201@2|Bacteria,3Y38D@57723|Acidobacteria	57723|Acidobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SYD2_k127_3244889_3	289376.THEYE_A1836	1.13e-59	213.0	COG0563@1|root,COG0563@2|Bacteria,3J0K3@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SYD2_k127_3244889_1	1123288.SOV_2c10180	3.593e-94	315.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H2VZ@909932|Negativicutes	909932|Negativicutes	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SYD2_k127_3244889_11	1382359.JIAL01000001_gene1718	2.715e-09	58.0	COG0361@1|root,COG0361@2|Bacteria,3Y55Z@57723|Acidobacteria,2JJUQ@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SYD2_k127_3250203_2	204669.Acid345_3442	5.777e-44	166.0	COG1388@1|root,COG1388@2|Bacteria,3Y4VG@57723|Acidobacteria,2JN09@204432|Acidobacteriia	204432|Acidobacteriia	M	Domain of Unknown Function (DUF1259)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1529
SYD2_k127_3250203_1	700598.Niako_6986	4.111e-81	285.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
SYD2_k127_3250203_0	204669.Acid345_0818	2.856e-130	444.0	COG2091@1|root,COG2091@2|Bacteria,3Y46J@57723|Acidobacteria,2JHWP@204432|Acidobacteriia	204432|Acidobacteriia	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3270412_0	748247.AZKH_2015	2.336e-163	520.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,2VVJQ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SYD2_k127_3270412_5	314230.DSM3645_09697	1.621e-18	87.0	COG3369@1|root,COG3369@2|Bacteria,2J45I@203682|Planctomycetes	203682|Planctomycetes	S	SMART zinc finger CDGSH-type domain protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
SYD2_k127_3270412_3	443144.GM21_2153	6.26e-30	126.0	COG4244@1|root,COG4244@2|Bacteria	2|Bacteria	E	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SYD2_k127_3270412_8	1408813.AYMG01000011_gene854	3.076e-12	72.0	COG2259@1|root,COG2259@2|Bacteria,4NSHK@976|Bacteroidetes,1ITP8@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SYD2_k127_3270412_7	62928.azo2665	6.723e-14	81.0	COG2353@1|root,COG2353@2|Bacteria,1N3P9@1224|Proteobacteria,2VSMB@28216|Betaproteobacteria,2KZ87@206389|Rhodocyclales	206389|Rhodocyclales	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SYD2_k127_3270412_4	1047013.AQSP01000139_gene2414	3.754e-28	123.0	COG0457@1|root,COG0457@2|Bacteria,2NRWN@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3270412_6	1349785.BAUG01000028_gene1680	1.106e-15	83.0	COG2259@1|root,COG2259@2|Bacteria,4NVWM@976|Bacteroidetes,1I5GY@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SYD2_k127_3270412_2	555079.Toce_0622	5.963e-44	172.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,42GDJ@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SYD2_k127_3270412_1	204669.Acid345_3110	5.818e-145	466.0	COG2876@1|root,COG2876@2|Bacteria,3Y64W@57723|Acidobacteria,2JMIX@204432|Acidobacteriia	204432|Acidobacteriia	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SYD2_k127_3270412_9	443143.GM18_1694	6.275e-07	54.0	COG1605@1|root,COG1605@2|Bacteria,1Q1RX@1224|Proteobacteria,42U9H@68525|delta/epsilon subdivisions,2WQ7P@28221|Deltaproteobacteria,43SMW@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Chorismate mutase type II	-	-	5.4.99.5	ko:K04093	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
SYD2_k127_3297780_2	204669.Acid345_0571	6.556e-73	248.0	COG1109@1|root,COG1109@2|Bacteria,3Y2F7@57723|Acidobacteria,2JHIV@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha beta alpha domain I	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SYD2_k127_3297780_0	204669.Acid345_0570	1.116e-158	511.0	COG0836@1|root,COG0836@2|Bacteria,3Y2W2@57723|Acidobacteria,2JI4D@204432|Acidobacteriia	204432|Acidobacteriia	M	mannose-6-phosphate isomerase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
SYD2_k127_3297780_1	204669.Acid345_0569	5.226e-120	393.0	COG1482@1|root,COG1482@2|Bacteria,3Y44Q@57723|Acidobacteria,2JIZ8@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphomannose isomerase type I	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
SYD2_k127_3297780_3	1340493.JNIF01000003_gene3292	8.818e-20	99.0	COG1287@1|root,COG1287@2|Bacteria,3Y5FJ@57723|Acidobacteria	57723|Acidobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3297991_0	631454.N177_3039	8.073e-133	437.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,1JNY6@119043|Rhodobiaceae	28211|Alphaproteobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SYD2_k127_3297991_1	1297569.MESS2_20014	2.405e-85	293.0	COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria,2TU0X@28211|Alphaproteobacteria,43M7T@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SYD2_k127_3301499_1	518766.Rmar_0925	2.296e-140	467.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1FJ9E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
SYD2_k127_3301499_3	234267.Acid_4784	1.228e-114	389.0	COG0591@1|root,COG0591@2|Bacteria,3Y419@57723|Acidobacteria	57723|Acidobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SYD2_k127_3301499_5	234267.Acid_7426	2.923e-81	282.0	COG2103@1|root,COG2103@2|Bacteria,3Y378@57723|Acidobacteria	57723|Acidobacteria	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	-	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS_2
SYD2_k127_3301499_8	1303518.CCALI_00692	9.412e-40	160.0	COG2971@1|root,COG2971@2|Bacteria	2|Bacteria	G	N-acetylglucosamine kinase activity	nagk	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363	2.7.1.59	ko:K00884	ko00520,ko01100,map00520,map01100	-	R01201	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	BcrAD_BadFG
SYD2_k127_3301499_7	864073.HFRIS_019408	1.232e-42	168.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VIX7@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SYD2_k127_3301499_6	335543.Sfum_0911	7.223e-57	212.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PZJ@68525|delta/epsilon subdivisions,2WMGB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Aminotransferase, class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SYD2_k127_3301499_4	1379270.AUXF01000004_gene3287	8.857e-102	348.0	COG0247@1|root,COG0247@2|Bacteria,1ZSTK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG
SYD2_k127_3301499_0	318586.Pden_0660	2.006e-171	556.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,2PUGP@265|Paracoccus	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SYD2_k127_3301499_2	1382304.JNIL01000001_gene3132	2.635e-138	475.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli	91061|Bacilli	C	COG0277 FAD FMN-containing dehydrogenases	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SYD2_k127_3301499_9	631454.N177_3158	2.646e-19	91.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,1JQN9@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SYD2_k127_3339039_7	234267.Acid_0799	1.476e-47	179.0	COG0681@1|root,COG0681@2|Bacteria,3Y49Z@57723|Acidobacteria	57723|Acidobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SYD2_k127_3339039_13	204669.Acid345_1185	1.373e-34	136.0	COG0776@1|root,COG0776@2|Bacteria,3Y4U4@57723|Acidobacteria,2JP27@204432|Acidobacteriia	204432|Acidobacteriia	L	bacterial (prokaryotic) histone like domain	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SYD2_k127_3339039_9	351160.LRC239	7.723e-47	182.0	COG0750@1|root,arCOG00609@2157|Archaea,2XT29@28890|Euryarchaeota,2NACS@224756|Methanomicrobia	224756|Methanomicrobia	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SYD2_k127_3339039_21	351348.Maqu_2688	3.007e-17	83.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,1SC7M@1236|Gammaproteobacteria,468WS@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
SYD2_k127_3339039_18	316067.Geob_1304	3.995e-25	112.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,43VCD@69541|Desulfuromonadales	28221|Deltaproteobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SYD2_k127_3339039_2	1122603.ATVI01000007_gene1801	4.905e-277	874.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1X4Q2@135614|Xanthomonadales	135614|Xanthomonadales	S	transporter	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SYD2_k127_3339039_8	1340493.JNIF01000004_gene505	3.866e-47	186.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
SYD2_k127_3339039_4	1122222.AXWR01000035_gene220	6.67e-140	451.0	COG0205@1|root,COG0205@2|Bacteria,1WM4B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
SYD2_k127_3339039_3	595494.Tola_1286	1.608e-202	648.0	COG0469@1|root,COG0469@2|Bacteria,1NNNX@1224|Proteobacteria,1RYF5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Pyruvate kinase	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
SYD2_k127_3339039_20	1479237.JMLY01000001_gene2639	2.735e-19	94.0	COG0517@1|root,COG0517@2|Bacteria,1QTVM@1224|Proteobacteria,1SFWU@1236|Gammaproteobacteria,46BCN@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SYD2_k127_3339039_14	886293.Sinac_4160	2.203e-34	138.0	COG0071@1|root,COG0071@2|Bacteria,2J11X@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SYD2_k127_3339039_17	161156.JQKW01000006_gene1370	2.21e-25	112.0	COG1499@1|root,COG1499@2|Bacteria,2GHJ0@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3339039_10	246197.MXAN_4249	8.408e-40	158.0	COG2823@1|root,COG5637@1|root,COG2823@2|Bacteria,COG5637@2|Bacteria,1RI3F@1224|Proteobacteria,437A8@68525|delta/epsilon subdivisions,2X2EK@28221|Deltaproteobacteria,2YVIY@29|Myxococcales	28221|Deltaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SYD2_k127_3339039_16	91464.S7335_4840	2.717e-26	115.0	COG0515@1|root,COG0515@2|Bacteria,1GP0N@1117|Cyanobacteria,1H21K@1129|Synechococcus	1117|Cyanobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3339039_19	1232437.KL662073_gene1746	4.663e-22	107.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,42QGY@68525|delta/epsilon subdivisions,2WKHR@28221|Deltaproteobacteria,2MJDT@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SYD2_k127_3339039_12	1123508.JH636456_gene127	1.676e-35	143.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
SYD2_k127_3339039_11	1869.MB27_30450	5.383e-36	145.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria	201174|Actinobacteria	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SYD2_k127_3339039_0	671143.DAMO_1138	0.0	1153.0	COG3383@1|root,COG3383@2|Bacteria,2NNQ6@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	fdxB	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_10,Fer4_4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SYD2_k127_3339039_6	682795.AciX8_2613	1.971e-57	211.0	COG1127@1|root,COG1127@2|Bacteria,3Y3YI@57723|Acidobacteria,2JIF1@204432|Acidobacteriia	204432|Acidobacteriia	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SYD2_k127_3339039_1	1267535.KB906767_gene2871	4.727e-299	943.0	COG0474@1|root,COG0474@2|Bacteria,3Y3ZX@57723|Acidobacteria,2JMFS@204432|Acidobacteriia	204432|Acidobacteriia	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SYD2_k127_3339039_15	1086011.HJ01_03285	1.118e-29	125.0	COG0589@1|root,COG0589@2|Bacteria,4NJ0H@976|Bacteroidetes,1I0HV@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SYD2_k127_3339039_5	314230.DSM3645_28077	3.228e-67	234.0	COG5340@1|root,COG5340@2|Bacteria,2J1R0@203682|Planctomycetes	203682|Planctomycetes	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3392338_0	765420.OSCT_2674	3.757e-31	139.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,2G7J8@200795|Chloroflexi,374RZ@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
SYD2_k127_3392338_2	102232.GLO73106DRAFT_00016960	9.548e-12	78.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,HTH_8,Sigma54_activat,Trans_reg_C,Yop-YscD_cpl
SYD2_k127_3392338_1	63737.Npun_R1867	8.113e-14	83.0	COG0457@1|root,COG0457@2|Bacteria,1G39E@1117|Cyanobacteria,1HQX3@1161|Nostocales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2,TPR_8
SYD2_k127_3401794_0	1121920.AUAU01000018_gene1783	2.019e-201	636.0	COG1506@1|root,COG1506@2|Bacteria,3Y3XQ@57723|Acidobacteria	57723|Acidobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SYD2_k127_3401794_2	234267.Acid_7662	8.71e-154	504.0	COG0160@1|root,COG0160@2|Bacteria,3Y4EV@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.55	ko:K00823,ko:K15372	ko00250,ko00410,ko00430,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00430,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R01684	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SYD2_k127_3401794_1	525904.Tter_0560	4.432e-156	509.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	ycbD	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SYD2_k127_3401794_3	1172186.KB911465_gene4584	2.197e-05	50.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,233YJ@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,PP-binding,Thioesterase
SYD2_k127_3441462_1	234267.Acid_1536	3.117e-190	614.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3IB@57723|Acidobacteria	57723|Acidobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SYD2_k127_3441462_6	329726.AM1_3686	7.8e-33	133.0	COG0454@1|root,COG0456@2|Bacteria,1G6J0@1117|Cyanobacteria	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SYD2_k127_3441462_8	1196323.ALKF01000200_gene2773	2.065e-07	57.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB1C@91061|Bacilli,26QDY@186822|Paenibacillaceae	91061|Bacilli	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
SYD2_k127_3441462_3	204669.Acid345_0995	1.871e-152	491.0	COG3191@1|root,COG3191@2|Bacteria,3Y699@57723|Acidobacteria	57723|Acidobacteria	M	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
SYD2_k127_3441462_9	929562.Emtol_0553	6.143e-07	52.0	2EHP7@1|root,33BF0@2|Bacteria,4NYRZ@976|Bacteroidetes,47SMN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3441462_5	1123371.ATXH01000045_gene1871	2.198e-58	215.0	28I4Y@1|root,2Z88D@2|Bacteria,2GI90@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3441462_4	1267534.KB906754_gene3509	2.102e-130	430.0	COG5368@1|root,COG5368@2|Bacteria,3Y2MM@57723|Acidobacteria,2JI52@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
SYD2_k127_3441462_0	469383.Cwoe_5411	3.976e-278	875.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SYD2_k127_3441462_7	113395.AXAI01000009_gene2454	1.471e-23	115.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,3JRSC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_12,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
SYD2_k127_3441462_2	234267.Acid_6939	8.098e-156	505.0	COG1629@1|root,COG4771@2|Bacteria,3Y2MF@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SYD2_k127_3441968_1	314285.KT71_10667	7.719e-65	229.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN3T@1236|Gammaproteobacteria,1J961@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Trypsin	degP	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SYD2_k127_3441968_2	335541.Swol_1572	3.54e-38	147.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,42K5B@68298|Syntrophomonadaceae	186801|Clostridia	FG	Scavenger mRNA decapping enzyme C-term binding	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SYD2_k127_3441968_0	234267.Acid_7425	7.597e-148	479.0	COG0766@1|root,COG0766@2|Bacteria,3Y2IC@57723|Acidobacteria	57723|Acidobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SYD2_k127_3482618_11	1407650.BAUB01000009_gene1849	1.389e-24	106.0	COG1131@1|root,COG1131@2|Bacteria,1G0RY@1117|Cyanobacteria,1H020@1129|Synechococcus	1117|Cyanobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SYD2_k127_3482618_6	1267535.KB906767_gene2095	1.664e-126	416.0	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	yhiI	-	-	ko:K01993,ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SYD2_k127_3482618_0	234267.Acid_2365	0.0	1602.0	COG0841@1|root,COG1538@1|root,COG0841@2|Bacteria,COG1538@2|Bacteria,3Y6DS@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
SYD2_k127_3482618_8	234267.Acid_2364	4.229e-83	291.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SYD2_k127_3482618_9	671143.DAMO_1259	1.607e-40	158.0	COG1309@1|root,COG1309@2|Bacteria,2NQ8G@2323|unclassified Bacteria	2|Bacteria	K	Bacterial regulatory proteins, tetR family	MA20_16815	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SYD2_k127_3482618_10	203122.Sde_0642	3.765e-31	132.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
SYD2_k127_3482618_1	340099.Teth39_0902	6.213e-236	741.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,42FIA@68295|Thermoanaerobacterales	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SYD2_k127_3482618_7	1267535.KB906767_gene1253	2.26e-101	340.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SYD2_k127_3482618_2	246197.MXAN_6050	2.159e-198	632.0	COG0457@1|root,COG0457@2|Bacteria,1Q3YA@1224|Proteobacteria,437VH@68525|delta/epsilon subdivisions,2X354@28221|Deltaproteobacteria,2YUAY@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M49
SYD2_k127_3482618_3	1454004.AW11_01665	3.408e-176	565.0	COG2301@1|root,COG2301@2|Bacteria,1R7U2@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
SYD2_k127_3482618_12	204669.Acid345_2692	1.028e-18	100.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3482618_5	1340493.JNIF01000003_gene4071	1.408e-137	452.0	COG0520@1|root,COG0520@2|Bacteria,3Y4TH@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SYD2_k127_3482618_4	234267.Acid_7272	1.097e-153	499.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,3Y2IR@57723|Acidobacteria	57723|Acidobacteria	P	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
SYD2_k127_3482618_13	290315.Clim_0050	5.31e-16	85.0	2EDTP@1|root,337NZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3510276_2	234267.Acid_2875	1.409e-147	477.0	COG3844@1|root,COG3844@2|Bacteria,3Y984@57723|Acidobacteria	57723|Acidobacteria	F	Aminotransferase class-V	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SYD2_k127_3510276_0	502025.Hoch_0175	1.146e-213	673.0	COG1902@1|root,COG1902@2|Bacteria,1R4A8@1224|Proteobacteria,42YBR@68525|delta/epsilon subdivisions,2WU33@28221|Deltaproteobacteria,2YXDW@29|Myxococcales	28221|Deltaproteobacteria	C	NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
SYD2_k127_3510276_7	485913.Krac_2149	5.832e-112	374.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,2G872@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
SYD2_k127_3510276_11	204669.Acid345_1475	1.824e-102	348.0	COG0436@1|root,COG0436@2|Bacteria,3Y5AV@57723|Acidobacteria,2JJXH@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SYD2_k127_3510276_4	204669.Acid345_1474	4.858e-141	465.0	COG1113@1|root,COG1113@2|Bacteria	2|Bacteria	E	amino acid transport	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SYD2_k127_3510276_8	1121939.L861_19615	1.489e-110	369.0	COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,1RYKP@1236|Gammaproteobacteria,1XNZN@135619|Oceanospirillales	135619|Oceanospirillales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SYD2_k127_3510276_23	240016.ABIZ01000001_gene2120	2.958e-11	64.0	COG1943@1|root,COG1943@2|Bacteria,46VEW@74201|Verrucomicrobia,2IVQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3510276_17	794903.OPIT5_20525	7.235e-63	220.0	COG1943@1|root,COG1943@2|Bacteria,46XEX@74201|Verrucomicrobia,3K9MH@414999|Opitutae	414999|Opitutae	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	-
SYD2_k127_3510276_15	485913.Krac_2147	1.211e-81	279.0	COG1024@1|root,COG1024@2|Bacteria,2G6G6@200795|Chloroflexi	2|Bacteria	I	PFAM Enoyl-CoA hydratase isomerase	MA20_38145	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SYD2_k127_3510276_20	204669.Acid345_0146	1.026e-32	138.0	COG0342@1|root,COG0342@2|Bacteria,3Y37S@57723|Acidobacteria,2JHJC@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SYD2_k127_3510276_19	1231392.OCGS_2767	1.485e-33	133.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2U9A9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SYD2_k127_3510276_24	272134.KB731324_gene1857	9.322e-05	55.0	COG1413@1|root,COG1413@2|Bacteria,1G341@1117|Cyanobacteria,1H8KK@1150|Oscillatoriales	1117|Cyanobacteria	C	PFAM PBS lyase HEAT-like repeat	nblB	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SYD2_k127_3510276_21	63737.Npun_R1214	1.775e-32	132.0	COG0346@1|root,COG0346@2|Bacteria,1GHQQ@1117|Cyanobacteria,1HPG9@1161|Nostocales	1117|Cyanobacteria	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SYD2_k127_3510276_16	204669.Acid345_4703	5.68e-65	228.0	COG2318@1|root,COG2318@2|Bacteria,3Y4AI@57723|Acidobacteria,2JKRK@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
SYD2_k127_3510276_3	926550.CLDAP_00120	1.877e-141	464.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi	200795|Chloroflexi	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SYD2_k127_3510276_1	886293.Sinac_0940	3.54e-202	647.0	COG2234@1|root,COG2234@2|Bacteria,2IZHS@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SYD2_k127_3510276_6	502558.EGYY_11580	1.62e-116	384.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4CV2B@84998|Coriobacteriia	84998|Coriobacteriia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SYD2_k127_3510276_5	1051632.TPY_0985	2.167e-126	412.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WCUJ@538999|Clostridiales incertae sedis	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SYD2_k127_3510276_22	234267.Acid_1121	4.67e-14	83.0	2BRBT@1|root,32KAC@2|Bacteria,3Y4U0@57723|Acidobacteria	57723|Acidobacteria	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
SYD2_k127_3510276_12	234267.Acid_1724	3.349e-100	341.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SYD2_k127_3510276_13	234267.Acid_1725	3.278e-88	306.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SYD2_k127_3510276_9	1379698.RBG1_1C00001G1367	4.161e-105	355.0	COG0577@1|root,COG0577@2|Bacteria,2NNN0@2323|unclassified Bacteria	2|Bacteria	V	COGs COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SYD2_k127_3510276_14	1382359.JIAL01000001_gene1381	1.516e-83	295.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria,2JI8C@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SYD2_k127_3510276_10	1267535.KB906767_gene3077	5.891e-104	343.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria,2JI7R@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SYD2_k127_3510276_18	204669.Acid345_3323	3.717e-59	223.0	COG0845@1|root,COG0845@2|Bacteria,3Y2XR@57723|Acidobacteria,2JHTV@204432|Acidobacteriia	204432|Acidobacteriia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SYD2_k127_3536051_1	483219.LILAB_23300	6.64e-39	150.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria	1224|Proteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
SYD2_k127_3536051_2	251229.Chro_3946	8.555e-23	107.0	COG0399@1|root,COG0399@2|Bacteria,1GJK5@1117|Cyanobacteria,3VKFF@52604|Pleurocapsales	1117|Cyanobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SYD2_k127_3536051_3	251229.Chro_3946	2.639e-05	50.0	COG0399@1|root,COG0399@2|Bacteria,1GJK5@1117|Cyanobacteria,3VKFF@52604|Pleurocapsales	1117|Cyanobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SYD2_k127_3536051_0	555088.DealDRAFT_1267	2.595e-63	231.0	COG1721@1|root,COG1721@2|Bacteria,1UYJ3@1239|Firmicutes,24FK2@186801|Clostridia	186801|Clostridia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SYD2_k127_3554194_1	470.IX87_09825	4.428e-38	145.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S28H@1236|Gammaproteobacteria,3NJTE@468|Moraxellaceae	1236|Gammaproteobacteria	M	Transglycosylase SLT domain	yjbJ	-	-	-	-	-	-	-	-	-	-	-	SLT
SYD2_k127_3554194_0	234267.Acid_0372	1.383e-124	413.0	COG3104@1|root,COG3104@2|Bacteria,3Y6W5@57723|Acidobacteria	57723|Acidobacteria	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SYD2_k127_357818_6	246197.MXAN_1012	8.817e-26	109.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,43BFP@68525|delta/epsilon subdivisions,2WMVT@28221|Deltaproteobacteria,2YVTT@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SYD2_k127_357818_5	1340493.JNIF01000004_gene1042	3.544e-32	141.0	2DUZM@1|root,33T72@2|Bacteria,3Y7AK@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_357818_0	379066.GAU_0147	3.165e-129	428.0	COG3391@1|root,COG3391@2|Bacteria,1ZUF6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_357818_4	1396141.BATP01000004_gene5936	3.077e-36	139.0	COG1943@1|root,COG1943@2|Bacteria,46VP6@74201|Verrucomicrobia,2IVSQ@203494|Verrucomicrobiae	74201|Verrucomicrobia	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SYD2_k127_357818_8	497964.CfE428DRAFT_1207	4.088e-08	55.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SYD2_k127_357818_7	240015.ACP_3477	6.539e-11	73.0	COG0810@1|root,COG0810@2|Bacteria,3Y58J@57723|Acidobacteria,2JJPH@204432|Acidobacteriia	204432|Acidobacteriia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
SYD2_k127_357818_1	379066.GAU_0146	3.138e-110	383.0	COG5276@1|root,COG5492@1|root,COG5276@2|Bacteria,COG5492@2|Bacteria,1ZU8T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SYD2_k127_357818_2	395961.Cyan7425_2624	3.636e-105	351.0	COG0491@1|root,COG1141@1|root,COG0491@2|Bacteria,COG1141@2|Bacteria,1G3D1@1117|Cyanobacteria,3KHIR@43988|Cyanothece	1117|Cyanobacteria	C	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
SYD2_k127_357818_3	748727.CLJU_c21290	1.346e-50	182.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,36DT7@31979|Clostridiaceae	186801|Clostridia	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS10450	Aminotran_1_2
SYD2_k127_3626162_1	234267.Acid_5231	9.015e-102	340.0	COG0213@1|root,COG0213@2|Bacteria,3Y44B@57723|Acidobacteria	57723|Acidobacteria	F	PFAM Glycosyl transferase, family	-	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SYD2_k127_3626162_3	518766.Rmar_1099	9.698e-48	175.0	COG0245@1|root,COG0245@2|Bacteria,4NP0N@976|Bacteroidetes,1FJAC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
SYD2_k127_3626162_2	1120973.AQXL01000112_gene1049	1.92e-48	181.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HH2N@91061|Bacilli,278HX@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SYD2_k127_3626162_0	234267.Acid_1863	1.506e-124	408.0	COG4956@1|root,COG4956@2|Bacteria,3Y2RT@57723|Acidobacteria	57723|Acidobacteria	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
SYD2_k127_3627391_3	525904.Tter_2338	1.844e-101	341.0	COG2239@1|root,COG2239@2|Bacteria,2NP79@2323|unclassified Bacteria	2|Bacteria	P	MgtE intracellular N domain	mgtE	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
SYD2_k127_3627391_2	485913.Krac_6826	1.986e-130	429.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS07840	Nramp
SYD2_k127_3627391_4	215803.DB30_3013	1.252e-60	230.0	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria,1QX62@1224|Proteobacteria,42S57@68525|delta/epsilon subdivisions,2WNY0@28221|Deltaproteobacteria,2YVPP@29|Myxococcales	28221|Deltaproteobacteria	MT	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
SYD2_k127_3627391_5	240015.ACP_2406	2.002e-42	160.0	COG0071@1|root,COG0071@2|Bacteria,3Y4TM@57723|Acidobacteria,2JJFI@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SYD2_k127_3627391_0	1121405.dsmv_2717	0.0	1120.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2MHW3@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SYD2_k127_3627391_1	1391646.AVSU01000051_gene1746	8.394e-141	474.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,25QH6@186804|Peptostreptococcaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SYD2_k127_3627391_6	1267535.KB906767_gene881	6.824e-09	66.0	2A6XZ@1|root,30VSX@2|Bacteria,3Y4RH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3627391_7	771875.Ferpe_0872	3.622e-07	63.0	COG2199@1|root,COG3706@2|Bacteria,2GCIY@200918|Thermotogae	200918|Thermotogae	T	response regulator	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
SYD2_k127_3627391_8	1120949.KB903317_gene1780	0.0001275	54.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4D8IM@85008|Micromonosporales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,TPR_7,Trans_reg_C
SYD2_k127_3654765_4	552811.Dehly_0227	5.643e-19	98.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	fdhA	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SYD2_k127_3654765_0	926566.Terro_1571	4.316e-111	370.0	COG1005@1|root,COG1005@2|Bacteria,3Y3VS@57723|Acidobacteria,2JHQZ@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SYD2_k127_3654765_3	1340493.JNIF01000003_gene1643	6.203e-25	113.0	COG0839@1|root,COG0839@2|Bacteria,3Y4I4@57723|Acidobacteria	57723|Acidobacteria	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SYD2_k127_3654765_2	204669.Acid345_1306	5.655e-31	127.0	COG0713@1|root,COG0713@2|Bacteria,3Y4XI@57723|Acidobacteria,2JJIM@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SYD2_k127_3654765_1	945713.IALB_1869	2.027e-98	331.0	COG1009@1|root,COG1009@2|Bacteria	2|Bacteria	CP	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SYD2_k127_3655894_0	1267535.KB906767_gene1457	5.135e-138	454.0	COG0188@1|root,COG0188@2|Bacteria,3Y2G5@57723|Acidobacteria,2JIR8@204432|Acidobacteriia	204432|Acidobacteriia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SYD2_k127_3655894_8	292459.STH3180	2.362e-54	199.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1V3V0@1239|Firmicutes,24QVX@186801|Clostridia	186801|Clostridia	H	Molybdopterin converting factor subunit	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SYD2_k127_3655894_13	861299.J421_2526	1.431e-42	168.0	COG2802@1|root,COG2802@2|Bacteria,1ZUZ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
SYD2_k127_3655894_9	266117.Rxyl_2043	2.49e-52	192.0	COG2154@1|root,COG2154@2|Bacteria,2HPFQ@201174|Actinobacteria,4CQU3@84995|Rubrobacteria	84995|Rubrobacteria	H	Transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SYD2_k127_3655894_12	926566.Terro_0661	2.314e-48	186.0	COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria,2JIK2@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3
SYD2_k127_3655894_11	204669.Acid345_0705	2.183e-48	187.0	COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria,2JI8N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SYD2_k127_3655894_14	111781.Lepto7376_3670	3.4e-15	91.0	COG2199@1|root,COG3706@2|Bacteria,1GBJE@1117|Cyanobacteria	1117|Cyanobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SYD2_k127_3655894_10	1173028.ANKO01000195_gene5983	1.153e-51	212.0	COG2202@1|root,COG2203@1|root,COG2905@1|root,COG3920@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2905@2|Bacteria,COG3920@2|Bacteria,1GHCI@1117|Cyanobacteria,1H8J3@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA_2,PAS,PAS_3,PAS_4,PAS_9
SYD2_k127_3655894_4	671143.DAMO_2120	1.957e-87	329.0	COG0745@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2NQ9F@2323|unclassified Bacteria	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg
SYD2_k127_3655894_6	243231.GSU0233	6.856e-58	208.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,42S8C@68525|delta/epsilon subdivisions,2WP10@28221|Deltaproteobacteria,43TU3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF480	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
SYD2_k127_3655894_7	682795.AciX8_4753	9.28e-55	215.0	COG4805@1|root,COG4805@2|Bacteria,3Y71M@57723|Acidobacteria,2JKC6@204432|Acidobacteriia	204432|Acidobacteriia	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SYD2_k127_3655894_5	1380394.JADL01000001_gene1986	3.883e-70	245.0	COG3757@1|root,COG3757@2|Bacteria,1R57X@1224|Proteobacteria,2U1NJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	M1 (1,4-beta-N-acetylmuramidase)	-	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25
SYD2_k127_3655894_2	518766.Rmar_0304	9.667e-90	305.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1FJQT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	4Fe-4S double cluster binding domain	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
SYD2_k127_3655894_1	383372.Rcas_1005	6.179e-94	319.0	COG0157@1|root,COG0157@2|Bacteria,2G6GJ@200795|Chloroflexi,375H1@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the NadC ModD family	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SYD2_k127_3655894_3	1283300.ATXB01000002_gene3088	7.604e-88	294.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,1XDJ1@135618|Methylococcales	1236|Gammaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0750,iAPECO1_1312.APECO1_1338,iB21_1397.B21_00692,iBWG_1329.BWG_0602,iECBD_1354.ECBD_2917,iECB_1328.ECB_00703,iECDH10B_1368.ECDH10B_0817,iECDH1ME8569_1439.ECDH1ME8569_0703,iECD_1391.ECD_00703,iECED1_1282.ECED1_0711,iECOK1_1307.ECOK1_0750,iECP_1309.ECP_0761,iECS88_1305.ECS88_0766,iECSP_1301.ECSP_0802,iECs_1301.ECs0778,iETEC_1333.ETEC_0754,iEcDH1_1363.EcDH1_2892,iEcolC_1368.EcolC_2912,iJN746.PP_1231,iJO1366.b0750,iJR904.b0750,iUMN146_1321.UM146_13905,iUTI89_1310.UTI89_C0747,iY75_1357.Y75_RS03905,iZ_1308.Z0919	NadA
SYD2_k127_366534_1	694427.Palpr_0195	5.324e-31	124.0	COG1943@1|root,COG1943@2|Bacteria,4NPPG@976|Bacteroidetes,2FTKF@200643|Bacteroidia,23217@171551|Porphyromonadaceae	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SYD2_k127_366534_0	1267535.KB906767_gene1780	2.558e-120	396.0	COG0604@1|root,COG0604@2|Bacteria,3Y6QN@57723|Acidobacteria	57723|Acidobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SYD2_k127_366534_2	1121035.AUCH01000017_gene2251	5.182e-12	73.0	COG0664@1|root,COG0668@1|root,COG0664@2|Bacteria,COG0668@2|Bacteria,1R6J6@1224|Proteobacteria,2VPCU@28216|Betaproteobacteria,2KXC3@206389|Rhodocyclales	206389|Rhodocyclales	MT	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
SYD2_k127_3666768_5	401053.AciPR4_2683	7.285e-05	51.0	COG4796@1|root,COG4796@2|Bacteria,3Y2G2@57723|Acidobacteria,2JKEJ@204432|Acidobacteriia	204432|Acidobacteriia	U	type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,Secretin
SYD2_k127_3666768_0	1267535.KB906767_gene3542	7.314e-218	690.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria,2JHVF@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SYD2_k127_3666768_1	1382359.JIAL01000001_gene1459	1.936e-78	277.0	COG1459@1|root,COG1459@2|Bacteria,3Y2X8@57723|Acidobacteria,2JHIX@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system F domain	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SYD2_k127_3666768_3	861299.J421_1409	1.623e-21	102.0	2EV6U@1|root,33NMK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3666768_2	861299.J421_1407	9.757e-40	154.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SYD2_k127_3675655_2	1173264.KI913950_gene4603	1.103e-41	157.0	2DNS7@1|root,32YWC@2|Bacteria,1GPZR@1117|Cyanobacteria,1HG4Q@1150|Oscillatoriales	1117|Cyanobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SYD2_k127_3675655_3	89187.ISM_08475	8.253e-35	145.0	29CWT@1|root,2ZZUX@2|Bacteria,1REF2@1224|Proteobacteria,2U7K7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	UPF0314 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2585
SYD2_k127_3675655_1	1341151.ASZU01000010_gene1916	2.372e-69	246.0	COG3253@1|root,COG3253@2|Bacteria,1VZPB@1239|Firmicutes,4HZ7E@91061|Bacilli,27B36@186824|Thermoactinomycetaceae	91061|Bacilli	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SYD2_k127_3675655_5	2340.JV46_05220	4.553e-06	55.0	COG2010@1|root,COG2010@2|Bacteria,1RGXM@1224|Proteobacteria,1SYJE@1236|Gammaproteobacteria,1JBAM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SYD2_k127_3675655_8	56780.SYN_03595	0.000173	47.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,42PXQ@68525|delta/epsilon subdivisions,2WKHU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SYD2_k127_3675655_0	1267535.KB906767_gene2453	0.0	1311.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,Trypsin_2
SYD2_k127_3675655_4	1394178.AWOO02000027_gene5300	1.194e-08	66.0	COG3595@1|root,COG3595@2|Bacteria,2GKT3@201174|Actinobacteria,4EHWS@85012|Streptosporangiales	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SYD2_k127_3675655_7	218497.CAB050	0.0001538	53.0	COG0457@1|root,COG0457@2|Bacteria	218497.CAB050|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3675655_6	1347086.CCBA010000034_gene2731	4.266e-05	50.0	COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,1ZCPW@1386|Bacillus	91061|Bacilli	S	COG0457 FOG TPR repeat	yrrB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
SYD2_k127_3679740_1	404589.Anae109_0242	6.222e-69	238.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WMNX@28221|Deltaproteobacteria,2Z31Y@29|Myxococcales	28221|Deltaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
SYD2_k127_3679740_2	404589.Anae109_0241	1.676e-46	175.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42VKD@68525|delta/epsilon subdivisions,2WRHY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rieske 2Fe-2S domain	pcmE	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
SYD2_k127_3679740_0	404589.Anae109_0240	1.02e-230	732.0	COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WKB4@28221|Deltaproteobacteria,2YTUD@29|Myxococcales	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
SYD2_k127_3679740_4	472759.Nhal_1081	3.647e-16	83.0	COG2010@1|root,COG2010@2|Bacteria,1PDUJ@1224|Proteobacteria,1SUEN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
SYD2_k127_3679740_3	338969.Rfer_0259	4.656e-31	128.0	COG3303@1|root,COG3303@2|Bacteria,1PEVM@1224|Proteobacteria,2VMWI@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
SYD2_k127_3727486_53	1120966.AUBU01000001_gene864	0.000611	46.0	COG0438@1|root,COG0438@2|Bacteria,4NU4C@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	remC	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
SYD2_k127_3727486_38	323259.Mhun_3143	6.463e-25	115.0	COG0500@1|root,arCOG01789@2157|Archaea,2Y7UC@28890|Euryarchaeota	28890|Euryarchaeota	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3727486_13	760192.Halhy_2892	2.01e-100	351.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1IR5W@117747|Sphingobacteriia	976|Bacteroidetes	E	asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SYD2_k127_3727486_36	1033991.RLEG12_13455	3.705e-28	128.0	COG0438@1|root,COG0438@2|Bacteria,1R6BX@1224|Proteobacteria,2TURB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SYD2_k127_3727486_29	203124.Tery_1479	2.624e-43	168.0	COG0500@1|root,COG1216@1|root,COG1216@2|Bacteria,COG2226@2|Bacteria,1G5DK@1117|Cyanobacteria,1HAXQ@1150|Oscillatoriales	1117|Cyanobacteria	Q	Methyltransferase type 11 Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11
SYD2_k127_3727486_22	269797.Mbar_A0237	7.001e-71	252.0	COG0463@1|root,arCOG01381@2157|Archaea,2XYGG@28890|Euryarchaeota	28890|Euryarchaeota	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SYD2_k127_3727486_9	247490.KSU1_D0083	2.741e-132	429.0	COG0451@1|root,COG0451@2|Bacteria,2IYBF@203682|Planctomycetes	203682|Planctomycetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
SYD2_k127_3727486_27	269799.Gmet_1493	9.803e-49	185.0	COG1216@1|root,COG1216@2|Bacteria,1RGUZ@1224|Proteobacteria,42SZI@68525|delta/epsilon subdivisions,2X7M1@28221|Deltaproteobacteria,43V61@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SYD2_k127_3727486_17	234267.Acid_4640	2.314e-89	303.0	COG1682@1|root,COG1682@2|Bacteria,3Y7JV@57723|Acidobacteria	57723|Acidobacteria	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SYD2_k127_3727486_11	32049.SYNPCC7002_A0418	6.821e-124	410.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,1H0E0@1129|Synechococcus	1117|Cyanobacteria	GM	ABC-type polysaccharide polyol phosphate transport system, ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
SYD2_k127_3727486_35	411477.PARMER_01968	2.382e-28	124.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,Fer4_7,FrhB_FdhB_C,Hexapep
SYD2_k127_3727486_15	1121272.KB903253_gene6883	4.676e-90	309.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4DCYX@85008|Micromonosporales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SYD2_k127_3727486_40	1227499.C493_17101	1.607e-19	101.0	COG1208@1|root,arCOG00664@2157|Archaea,2XTG9@28890|Euryarchaeota,23T96@183963|Halobacteria	183963|Halobacteria	M	COG1209 dTDP-glucose pyrophosphorylase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SYD2_k127_3727486_42	755731.Clo1100_2799	3.039e-17	94.0	COG0494@1|root,COG0535@1|root,COG0494@2|Bacteria,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,36E8H@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,NUDIX,PqqD,Radical_SAM,SPASM
SYD2_k127_3727486_43	1298867.AUES01000001_gene1611	4.17e-14	81.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,2TV8R@28211|Alphaproteobacteria,3JRAV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Methionine biosynthesis protein MetW	pmtA	-	2.1.1.17,2.1.1.71	ko:K00570	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00091	R01320,R02056,R03424	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
SYD2_k127_3727486_10	479434.Sthe_1140	4.012e-124	409.0	COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SYD2_k127_3727486_48	2880.D8LMR1	1.272e-05	57.0	COG2227@1|root,KOG1270@2759|Eukaryota	2759|Eukaryota	H	hexaprenyldihydroxybenzoate methyltransferase activity	COQ3	GO:0003674,GO:0003824,GO:0004395,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008757,GO:0009058,GO:0009108,GO:0009987,GO:0010420,GO:0016020,GO:0016740,GO:0016741,GO:0019866,GO:0019898,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032259,GO:0042180,GO:0042181,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0061542,GO:0061543,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.114,2.1.1.222,2.1.1.64	ko:K00568,ko:K00591	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117,M00128	R02175,R04711,R04988,R05614,R07235,R08769,R08771,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
SYD2_k127_3727486_14	1192124.LIG30_2199	3.206e-94	321.0	COG4641@1|root,COG4641@2|Bacteria,1R62R@1224|Proteobacteria,2VY4U@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
SYD2_k127_3727486_18	927677.ALVU02000001_gene1862	3.537e-86	294.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	ubiE1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SYD2_k127_3727486_16	1173027.Mic7113_0503	1.698e-89	308.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	DUF4214,HTH_3,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25,Methyltransf_31
SYD2_k127_3727486_25	1123366.TH3_00405	5.171e-59	209.0	2BWTW@1|root,315N7@2|Bacteria,1RABY@1224|Proteobacteria,2U5VH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3727486_4	1123366.TH3_00400	1.346e-168	537.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TVTA@28211|Alphaproteobacteria,2JR9T@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SYD2_k127_3727486_47	1038860.AXAP01000049_gene2333	3.534e-09	68.0	29VPA@1|root,30H6N@2|Bacteria,1MYVJ@1224|Proteobacteria,2U9MK@28211|Alphaproteobacteria,3JZT6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3727486_30	1499967.BAYZ01000014_gene6383	1.108e-37	151.0	COG0500@1|root,COG2226@2|Bacteria,2NQ7F@2323|unclassified Bacteria	2|Bacteria	Q	Methyltransferase domain	eryCVI	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0046983	2.1.1.234	ko:K13311,ko:K13326,ko:K21335	ko00523,ko01130,map00523,map01130	M00797,M00800	R06427,R11045,R11476	RC00003,RC01515,RC02262	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
SYD2_k127_3727486_12	251229.Chro_4828	5.026e-116	386.0	COG0438@1|root,COG0438@2|Bacteria,1G23P@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SYD2_k127_3727486_28	383372.Rcas_1348	7.424e-44	172.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SYD2_k127_3727486_6	933262.AXAM01000068_gene2766	4.2e-140	452.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,42KZY@68525|delta/epsilon subdivisions,2WJ4B@28221|Deltaproteobacteria,2MN0X@213118|Desulfobacterales	28221|Deltaproteobacteria	M	RmlD substrate binding domain	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SYD2_k127_3727486_8	589865.DaAHT2_1931	1.86e-136	452.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,42NMY@68525|delta/epsilon subdivisions,2WJ8S@28221|Deltaproteobacteria,2MHS5@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SYD2_k127_3727486_1	452637.Oter_1442	1.392e-200	639.0	COG0737@1|root,COG0737@2|Bacteria,46VVX@74201|Verrucomicrobia	74201|Verrucomicrobia	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
SYD2_k127_3727486_51	306281.AJLK01000073_gene2589	0.000138	55.0	COG1807@1|root,COG1807@2|Bacteria,1G27Y@1117|Cyanobacteria,1JHTP@1189|Stigonemataceae	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SYD2_k127_3727486_44	671143.DAMO_2614	7.46e-13	80.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SYD2_k127_3727486_3	204669.Acid345_1131	1.76e-173	551.0	COG1960@1|root,COG1960@2|Bacteria,3Y32R@57723|Acidobacteria,2JIRM@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.99.12	ko:K00248,ko:K09478	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SYD2_k127_3727486_45	204536.SULAZ_1302	2.787e-12	71.0	COG4783@1|root,COG4783@2|Bacteria,2G573@200783|Aquificae	200783|Aquificae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SYD2_k127_3727486_0	1382359.JIAL01000001_gene1956	1.611e-304	950.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,3Y34Y@57723|Acidobacteria,2JHQ9@204432|Acidobacteriia	204432|Acidobacteriia	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SYD2_k127_3727486_24	886293.Sinac_1812	2.328e-64	225.0	COG4430@1|root,COG4430@2|Bacteria,2J0DY@203682|Planctomycetes	203682|Planctomycetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SYD2_k127_3727486_31	861299.J421_4343	5.273e-36	143.0	COG0262@1|root,COG0262@2|Bacteria,1ZU5U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SYD2_k127_3727486_52	1267535.KB906767_gene3577	0.000384	52.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria,2JJYF@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SYD2_k127_3727486_7	768704.Desmer_4639	5.629e-139	451.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,260HS@186807|Peptococcaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SYD2_k127_3727486_49	284031.JNXD01000003_gene3852	1.587e-05	55.0	COG4319@1|root,COG4319@2|Bacteria,2IMG5@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SYD2_k127_3727486_50	446468.Ndas_1757	3.65e-05	55.0	2BNAB@1|root,32GXX@2|Bacteria,2HF1P@201174|Actinobacteria,4EPYI@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SYD2_k127_3727486_5	671143.DAMO_2498	2.43e-159	509.0	COG1180@1|root,COG1180@2|Bacteria,2NP82@2323|unclassified Bacteria	2|Bacteria	O	Radical SAM superfamily	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SYD2_k127_3727486_26	258594.RPA0568	1.389e-52	194.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2TQJ9@28211|Alphaproteobacteria,3JT7M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	ycbL	GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SYD2_k127_3727486_32	932678.THERU_02135	1.691e-33	136.0	COG2346@1|root,COG2346@2|Bacteria,2G5AF@200783|Aquificae	200783|Aquificae	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SYD2_k127_3727486_39	1267533.KB906733_gene3397	1.109e-19	104.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SYD2_k127_3727486_33	1122134.KB893650_gene647	1.437e-32	129.0	COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,1S8V6@1236|Gammaproteobacteria,1XMAY@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
SYD2_k127_3727486_20	1379698.RBG1_1C00001G0812	3.359e-78	267.0	COG0177@1|root,COG0177@2|Bacteria,2NPBI@2323|unclassified Bacteria	2|Bacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SYD2_k127_3727486_23	66377.JOBH01000007_gene2046	3.525e-65	232.0	COG0596@1|root,COG0596@2|Bacteria,2GNFU@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SYD2_k127_3727486_37	861299.J421_4429	1.882e-25	112.0	COG0824@1|root,COG0824@2|Bacteria,1ZV5K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
SYD2_k127_3727486_46	530564.Psta_2919	1.421e-11	71.0	COG5349@1|root,COG5349@2|Bacteria,2J1NF@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
SYD2_k127_3727486_2	483219.LILAB_22025	6.995e-197	631.0	COG0457@1|root,COG0457@2|Bacteria,1NTKG@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3727486_34	1121920.AUAU01000023_gene2406	7.895e-29	130.0	2DMMW@1|root,32SIJ@2|Bacteria,3Y8YH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3727486_19	237368.SCABRO_03899	1.753e-84	289.0	COG1028@1|root,COG1028@2|Bacteria,2IXE0@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SYD2_k127_3727486_21	504472.Slin_1691	3.987e-75	269.0	COG4938@1|root,COG4938@2|Bacteria,4NPXH@976|Bacteroidetes,47X5K@768503|Cytophagia	976|Bacteroidetes	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
SYD2_k127_3727486_41	504472.Slin_1690	5.871e-19	93.0	299RQ@1|root,2ZWTY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_37830_4	1121931.AUHG01000011_gene2313	9.106e-05	46.0	COG2968@1|root,COG2968@2|Bacteria,4NPHH@976|Bacteroidetes,1I26H@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SYD2_k127_37830_2	661478.OP10G_4341	1.659e-174	561.0	COG2939@1|root,COG2939@2|Bacteria	2|Bacteria	E	PFAM Peptidase S10, serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
SYD2_k127_37830_0	215803.DB30_5624	1.373e-199	631.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,42PXH@68525|delta/epsilon subdivisions,2WKEX@28221|Deltaproteobacteria,2YTWX@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SYD2_k127_37830_3	1279009.ADICEAN_03991	1.48e-39	160.0	COG5624@1|root,COG5624@2|Bacteria,4NZQQ@976|Bacteroidetes	976|Bacteroidetes	K	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_37830_1	1121920.AUAU01000018_gene1783	1.61e-185	590.0	COG1506@1|root,COG1506@2|Bacteria,3Y3XQ@57723|Acidobacteria	57723|Acidobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SYD2_k127_3801580_0	1128421.JAGA01000002_gene269	2.227e-200	644.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SYD2_k127_3801580_2	234267.Acid_4370	3.697e-29	120.0	2DIW1@1|root,32UBV@2|Bacteria,3Y5BC@57723|Acidobacteria	57723|Acidobacteria	S	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SYD2_k127_3801580_1	1120973.AQXL01000109_gene1928	6.211e-72	251.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,2797K@186823|Alicyclobacillaceae	91061|Bacilli	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05245,iYO844.BSU06530	GARS_A,GARS_C,GARS_N
SYD2_k127_3835207_1	266117.Rxyl_3166	5.94e-148	488.0	COG0749@1|root,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CP7C@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_pol_A,DNA_pol_A_exo1
SYD2_k127_3835207_10	749222.Nitsa_1123	2.147e-15	80.0	COG1917@1|root,COG1917@2|Bacteria,1Q5S1@1224|Proteobacteria,432IR@68525|delta/epsilon subdivisions,2YSTP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SYD2_k127_3835207_8	82654.Pse7367_0065	2.684e-37	144.0	COG0780@1|root,COG0780@2|Bacteria,1G5W6@1117|Cyanobacteria,1HB47@1150|Oscillatoriales	1117|Cyanobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
SYD2_k127_3835207_4	743722.Sph21_3230	4.267e-93	312.0	COG0705@1|root,COG0705@2|Bacteria,4NJG9@976|Bacteroidetes,1J16X@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SYD2_k127_3835207_3	1434325.AZQN01000002_gene1083	1.44e-132	436.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,47KI1@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
SYD2_k127_3835207_5	1499967.BAYZ01000065_gene6109	3.622e-81	279.0	COG0061@1|root,COG0061@2|Bacteria,2NP7T@2323|unclassified Bacteria	2|Bacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895	NAD_kinase
SYD2_k127_3835207_6	644966.Tmar_1166	1.858e-78	269.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,3WCJM@538999|Clostridiales incertae sedis	186801|Clostridia	J	FtsJ-like methyltransferase	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SYD2_k127_3835207_0	401526.TcarDRAFT_1596	2.427e-218	695.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H236@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SYD2_k127_3835207_7	1128421.JAGA01000002_gene410	6.876e-43	162.0	COG0394@1|root,COG0394@2|Bacteria,2NPGV@2323|unclassified Bacteria	2|Bacteria	T	Low molecular weight phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SYD2_k127_3835207_9	639030.JHVA01000001_gene3432	1.497e-33	133.0	COG0640@1|root,COG0640@2|Bacteria,3Y7J1@57723|Acidobacteria,2JMRU@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SYD2_k127_3835207_2	1267535.KB906767_gene1145	3.057e-140	461.0	COG0008@1|root,COG0008@2|Bacteria,3Y465@57723|Acidobacteria,2JHZW@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SYD2_k127_3835207_11	1280944.HY17_03495	1.876e-05	55.0	COG4319@1|root,COG4319@2|Bacteria,1RDBF@1224|Proteobacteria,2U7AM@28211|Alphaproteobacteria,43Y3X@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SYD2_k127_389088_1	562970.Btus_1531	1.238e-121	402.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,2788P@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SYD2_k127_389088_12	867900.Celly_3047	2.816e-10	67.0	COG1714@1|root,COG1714@2|Bacteria,4NN48@976|Bacteroidetes,1I1AH@117743|Flavobacteriia	976|Bacteroidetes	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	Coa1,RDD
SYD2_k127_389088_8	443144.GM21_1490	6.616e-36	148.0	COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,42QTH@68525|delta/epsilon subdivisions,2WQ6V@28221|Deltaproteobacteria,43SXU@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM phosphatidate cytidylyltransferase	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SYD2_k127_389088_3	760568.Desku_2556	7.973e-79	272.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,260D7@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SYD2_k127_389088_5	1120973.AQXL01000112_gene1102	2.177e-54	201.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,279KN@186823|Alicyclobacillaceae	91061|Bacilli	J	tRNA pseudouridine synthase	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SYD2_k127_389088_4	1340493.JNIF01000003_gene4131	2.478e-55	201.0	COG0461@1|root,COG0461@2|Bacteria	2|Bacteria	F	orotate phosphoribosyltransferase activity	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SYD2_k127_389088_7	1094508.Tsac_1822	1.788e-37	152.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,42FB8@68295|Thermoanaerobacterales	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
SYD2_k127_389088_9	1340493.JNIF01000004_gene241	3.61e-19	95.0	COG1238@1|root,COG1238@2|Bacteria,3Y52F@57723|Acidobacteria	57723|Acidobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SYD2_k127_389088_10	204669.Acid345_4653	9.19e-18	92.0	COG1238@1|root,COG1238@2|Bacteria,3Y52F@57723|Acidobacteria,2JJK2@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SYD2_k127_389088_11	1379698.RBG1_1C00001G0758	4.626e-13	80.0	2ER9F@1|root,33IV2@2|Bacteria,2NRV9@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_389088_6	1380394.JADL01000009_gene3149	3.108e-52	190.0	COG4119@1|root,COG4119@2|Bacteria,1RHCE@1224|Proteobacteria,2U8N1@28211|Alphaproteobacteria,2JWUA@204441|Rhodospirillales	204441|Rhodospirillales	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SYD2_k127_389088_2	204669.Acid345_1701	9.469e-110	367.0	COG0153@1|root,COG0153@2|Bacteria,3Y300@57723|Acidobacteria,2JI7E@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SYD2_k127_389088_0	1242864.D187_001870	7.006e-134	435.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,42N94@68525|delta/epsilon subdivisions,2WJH4@28221|Deltaproteobacteria,2YY5W@29|Myxococcales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	galE1	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SYD2_k127_3903645_0	204669.Acid345_3357	5.986e-180	599.0	COG4191@1|root,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria,2JING@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
SYD2_k127_3903645_14	1382359.JIAL01000001_gene2868	0.0001871	54.0	COG3485@1|root,COG3485@2|Bacteria,3Y44E@57723|Acidobacteria,2JIGS@204432|Acidobacteriia	204432|Acidobacteriia	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SYD2_k127_3903645_2	1267533.KB906735_gene4732	3.902e-107	363.0	COG0612@1|root,COG0612@2|Bacteria,3Y3M9@57723|Acidobacteria,2JHY4@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SYD2_k127_3903645_5	204669.Acid345_4326	6.839e-61	220.0	COG1235@1|root,COG1235@2|Bacteria,3Y3DW@57723|Acidobacteria,2JI3X@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SYD2_k127_3903645_13	1007104.SUS17_808	7.225e-05	51.0	COG2197@1|root,COG2197@2|Bacteria,1RHWP@1224|Proteobacteria,2UA0I@28211|Alphaproteobacteria,2K0NR@204457|Sphingomonadales	204457|Sphingomonadales	KT	Protein of unknown function (DUF4019)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4019,GerE
SYD2_k127_3903645_1	269799.Gmet_1943	4.477e-165	531.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria,43TS7@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SYD2_k127_3903645_11	1197130.BAFM01000028_gene3097	8.967e-14	76.0	COG4818@1|root,arCOG04344@2157|Archaea,2Y00G@28890|Euryarchaeota,23XT0@183963|Halobacteria	183963|Halobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
SYD2_k127_3903645_10	656519.Halsa_1509	3.352e-15	81.0	COG4818@1|root,COG4818@2|Bacteria,1VBIZ@1239|Firmicutes,24XCH@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
SYD2_k127_3903645_9	204669.Acid345_0998	1.319e-21	98.0	COG1828@1|root,COG1828@2|Bacteria,3Y5NE@57723|Acidobacteria,2JJWM@204432|Acidobacteriia	204432|Acidobacteriia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SYD2_k127_3903645_4	204669.Acid345_2235	2.906e-99	328.0	COG0047@1|root,COG0047@2|Bacteria,3Y2YN@57723|Acidobacteria,2JIBA@204432|Acidobacteriia	204432|Acidobacteriia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SYD2_k127_3903645_7	29540.C481_02312	1.731e-33	139.0	COG1651@1|root,arCOG02868@2157|Archaea,2XW8R@28890|Euryarchaeota,23U3Q@183963|Halobacteria	183963|Halobacteria	OP	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SYD2_k127_3903645_12	1407650.BAUB01000001_gene94	5.633e-07	57.0	COG4243@1|root,COG4243@2|Bacteria,1FZWT@1117|Cyanobacteria,1GYP5@1129|Synechococcus	1117|Cyanobacteria	CO	Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
SYD2_k127_3903645_6	1191523.MROS_1419	7.864e-52	190.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SYD2_k127_3903645_8	1123057.P872_03625	3.872e-23	105.0	COG0526@1|root,COG1225@1|root,COG0526@2|Bacteria,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes,47K5E@768503|Cytophagia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SYD2_k127_3903645_3	1267535.KB906767_gene3786	2.811e-101	333.0	COG0046@1|root,COG0046@2|Bacteria,3Y30N@57723|Acidobacteria,2JHYK@204432|Acidobacteriia	204432|Acidobacteriia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SYD2_k127_3947366_5	289376.THEYE_A1642	8.382e-11	65.0	COG1966@1|root,COG1966@2|Bacteria,3J10E@40117|Nitrospirae	40117|Nitrospirae	T	5TM C-terminal transporter carbon starvation CstA	-	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
SYD2_k127_3947366_1	99598.Cal7507_5543	2.895e-188	592.0	COG1064@1|root,COG1064@2|Bacteria,1G0B9@1117|Cyanobacteria,1HMF1@1161|Nostocales	1117|Cyanobacteria	C	PFAM Alcohol dehydrogenase	-	-	-	ko:K12957,ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SYD2_k127_3947366_0	204669.Acid345_1918	0.0	1245.0	COG3808@1|root,COG3808@2|Bacteria,3Y34E@57723|Acidobacteria,2JJHT@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SYD2_k127_3947366_4	1089550.ATTH01000001_gene1141	1.63e-14	84.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1FK0T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SYD2_k127_3947366_3	1521187.JPIM01000060_gene2918	1.063e-44	169.0	COG1268@1|root,COG1268@2|Bacteria,2G969@200795|Chloroflexi,375QP@32061|Chloroflexia	32061|Chloroflexia	S	PFAM BioY protein	-	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SYD2_k127_3947366_2	562970.Btus_2079	4.972e-49	179.0	COG0454@1|root,COG0456@2|Bacteria,1V562@1239|Firmicutes,4HMAE@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SYD2_k127_395012_0	1123261.AXDW01000010_gene358	5.862e-233	746.0	COG5412@1|root,COG5412@2|Bacteria,1N710@1224|Proteobacteria,1S7X2@1236|Gammaproteobacteria,1X9ES@135614|Xanthomonadales	135614|Xanthomonadales	S	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_395012_1	177437.HRM2_13060	2.942e-64	240.0	COG0711@1|root,COG5412@1|root,COG0711@2|Bacteria,COG5412@2|Bacteria,1QWMX@1224|Proteobacteria,43BSU@68525|delta/epsilon subdivisions,2X73N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_396068_0	234267.Acid_6939	4.621e-229	730.0	COG1629@1|root,COG4771@2|Bacteria,3Y2MF@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SYD2_k127_396068_2	198467.NP92_12210	8.48e-129	423.0	COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,4HCK3@91061|Bacilli,21UZ3@150247|Anoxybacillus	91061|Bacilli	G	Periplasmic binding protein domain	-	-	-	ko:K02058,ko:K10543	ko02010,map02010	M00215,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.4	-	-	Peripla_BP_4
SYD2_k127_396068_6	105559.Nwat_0046	3.292e-43	163.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,1S8YK@1236|Gammaproteobacteria,1X28T@135613|Chromatiales	135613|Chromatiales	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SYD2_k127_396068_1	580331.Thit_0247	7.707e-178	571.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,42ESS@68295|Thermoanaerobacterales	186801|Clostridia	P	Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system	xylG	-	3.6.3.17	ko:K10441,ko:K10545	ko02010,map02010	M00212,M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.4	-	-	ABC_tran
SYD2_k127_396068_3	204669.Acid345_0905	4.098e-114	379.0	COG4214@1|root,COG4214@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K10544	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	BPD_transp_2
SYD2_k127_396068_4	316067.Geob_2880	5.921e-67	240.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,43BAY@68525|delta/epsilon subdivisions,2X6Q4@28221|Deltaproteobacteria,43W1H@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1639	ROK
SYD2_k127_396068_5	321327.CYA_1973	2.529e-51	184.0	COG1449@1|root,COG1449@2|Bacteria,1G0BM@1117|Cyanobacteria,1GYNP@1129|Synechococcus	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
SYD2_k127_3961834_20	204669.Acid345_0831	0.0003925	52.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_5
SYD2_k127_3961834_2	1123248.KB893386_gene1888	1.018e-161	519.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,1IVHN@117747|Sphingobacteriia	976|Bacteroidetes	P	COG1055 Na H antiporter NhaD and related arsenite	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
SYD2_k127_3961834_7	926566.Terro_0051	9.021e-114	376.0	COG0500@1|root,COG2226@2|Bacteria,3Y4HC@57723|Acidobacteria,2JKIK@204432|Acidobacteriia	204432|Acidobacteriia	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SYD2_k127_3961834_1	357808.RoseRS_1917	2.901e-169	539.0	COG0798@1|root,COG0798@2|Bacteria,2G5ZH@200795|Chloroflexi,37708@32061|Chloroflexia	32061|Chloroflexia	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
SYD2_k127_3961834_13	330214.NIDE3707	1.693e-49	180.0	COG0394@1|root,COG0394@2|Bacteria,3J1AU@40117|Nitrospirae	40117|Nitrospirae	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SYD2_k127_3961834_6	204669.Acid345_3131	1.739e-121	398.0	COG0306@1|root,COG0306@2|Bacteria,3Y3ZW@57723|Acidobacteria,2JIZT@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SYD2_k127_3961834_16	269799.Gmet_3132	1.242e-45	172.0	COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,42SPV@68525|delta/epsilon subdivisions,2WPTH@28221|Deltaproteobacteria,43SW8@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SYD2_k127_3961834_5	562970.Btus_2864	5.975e-126	412.0	COG0226@1|root,COG0226@2|Bacteria,1TYCT@1239|Firmicutes,4I7GX@91061|Bacilli,279TX@186823|Alicyclobacillaceae	91061|Bacilli	P	Belongs to the PstS family	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SYD2_k127_3961834_9	639030.JHVA01000001_gene270	2.778e-101	340.0	COG0573@1|root,COG0573@2|Bacteria,3Y42Y@57723|Acidobacteria,2JIJN@204432|Acidobacteriia	204432|Acidobacteriia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SYD2_k127_3961834_10	1198114.AciX9_1710	3.137e-85	291.0	COG0581@1|root,COG0581@2|Bacteria,3Y3JF@57723|Acidobacteria,2JHVP@204432|Acidobacteriia	204432|Acidobacteriia	P	Phosphate transport system permease protein PstA	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SYD2_k127_3961834_8	1112216.JH594425_gene3471	5.727e-104	344.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2TQX9@28211|Alphaproteobacteria,2JZZN@204457|Sphingomonadales	204457|Sphingomonadales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SYD2_k127_3961834_15	909663.KI867150_gene253	1.869e-47	178.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WMS0@28221|Deltaproteobacteria,2MSIV@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PhoU domain	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SYD2_k127_3961834_12	1348662.CARG_01840	2.126e-53	196.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,22K17@1653|Corynebacteriaceae	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	mtrA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SYD2_k127_3961834_11	644282.Deba_1067	6.039e-65	237.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SYD2_k127_3961834_19	446468.Ndas_1757	6.928e-06	55.0	2BNAB@1|root,32GXX@2|Bacteria,2HF1P@201174|Actinobacteria,4EPYI@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SYD2_k127_3961834_3	1382359.JIAL01000001_gene2242	4.574e-136	455.0	COG1190@1|root,COG1190@2|Bacteria,3Y3N0@57723|Acidobacteria,2JI1W@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SYD2_k127_3961834_14	1125863.JAFN01000001_gene3040	1.698e-48	179.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
SYD2_k127_3961834_0	1382359.JIAL01000001_gene901	2.536e-305	977.0	COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria,2JIHQ@204432|Acidobacteriia	204432|Acidobacteriia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SYD2_k127_3961834_18	765911.Thivi_1122	1.892e-16	91.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1WVWN@135613|Chromatiales	135613|Chromatiales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N
SYD2_k127_3961834_4	521674.Plim_3769	1.33e-126	412.0	COG2041@1|root,COG2041@2|Bacteria,2J1J7@203682|Planctomycetes	203682|Planctomycetes	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
SYD2_k127_3961834_17	198628.Dda3937_02536	1.007e-38	150.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RMF3@1236|Gammaproteobacteria,2JCHT@204037|Dickeya	1236|Gammaproteobacteria	P	PFAM sodium sulphate symporter	ybhI	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
SYD2_k127_3966972_1	67267.JNXT01000002_gene5941	5.137e-151	495.0	COG2234@1|root,COG2234@2|Bacteria,2I9YF@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SYD2_k127_3966972_2	1121015.N789_06360	1.409e-149	497.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,1RSEC@1236|Gammaproteobacteria,1X44S@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
SYD2_k127_3966972_0	1379270.AUXF01000002_gene1789	3.419e-151	489.0	COG4102@1|root,COG4102@2|Bacteria,1ZSZ1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SYD2_k127_3966972_5	1469607.KK073769_gene5434	4.135e-46	169.0	COG0614@1|root,COG0614@2|Bacteria,1G79B@1117|Cyanobacteria,1HNFV@1161|Nostocales	1117|Cyanobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
SYD2_k127_3966972_4	518766.Rmar_1973	4.339e-96	321.0	COG1878@1|root,COG1878@2|Bacteria,4PIWM@976|Bacteroidetes,1FJPB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Putative cyclase	-	GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
SYD2_k127_3966972_6	1268072.PSAB_15720	3.296e-42	165.0	COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,26QTA@186822|Paenibacillaceae	91061|Bacilli	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SYD2_k127_3966972_3	886293.Sinac_4664	3.853e-123	409.0	COG1819@1|root,COG1819@2|Bacteria,2IZT0@203682|Planctomycetes	203682|Planctomycetes	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
SYD2_k127_3966972_7	643473.KB235930_gene1236	2.936e-30	121.0	COG1724@1|root,COG1724@2|Bacteria,1G9SX@1117|Cyanobacteria,1HPVQ@1161|Nostocales	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SYD2_k127_3966972_8	32057.KB217478_gene6503	4.646e-20	91.0	COG1598@1|root,COG1598@2|Bacteria,1G9I1@1117|Cyanobacteria,1HPTW@1161|Nostocales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3966972_9	1266925.JHVX01000003_gene577	2.031e-12	69.0	2CK1A@1|root,2ZYMN@2|Bacteria,1RFG1@1224|Proteobacteria,2VRIP@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_3987552_5	661478.OP10G_3245	1.266e-42	160.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SYD2_k127_3987552_3	452471.Aasi_0623	5.688e-72	248.0	29KMP@1|root,2Z9ZF@2|Bacteria,4NKVK@976|Bacteroidetes,47QGW@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4287)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
SYD2_k127_3987552_4	1379698.RBG1_1C00001G0272	1.323e-50	184.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,DUF2505
SYD2_k127_3987552_0	472759.Nhal_1379	2.117e-273	863.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1S0BH@1236|Gammaproteobacteria,1X076@135613|Chromatiales	135613|Chromatiales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SYD2_k127_3987552_7	1123368.AUIS01000006_gene597	3.207e-26	114.0	COG0071@1|root,COG0071@2|Bacteria,1NPJI@1224|Proteobacteria,1SRY5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SYD2_k127_3987552_1	1118058.CAGY01000001_gene597	2.688e-196	622.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4D3ID@85005|Actinomycetales	201174|Actinobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SYD2_k127_3987552_2	945713.IALB_2314	7.422e-78	287.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SYD2_k127_3987552_8	1348114.OM33_08730	1.352e-18	92.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,2Q1UP@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
SYD2_k127_3998260_0	452637.Oter_4614	3.089e-207	663.0	COG3590@1|root,COG3590@2|Bacteria,46UUX@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Peptidase family M13	-	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
SYD2_k127_3998260_2	204669.Acid345_3700	1.524e-100	337.0	COG2025@1|root,COG2025@2|Bacteria,3Y4SJ@57723|Acidobacteria,2JP3Y@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SYD2_k127_3998260_3	234267.Acid_1166	8.886e-79	271.0	COG2086@1|root,COG2086@2|Bacteria,3Y2PD@57723|Acidobacteria	57723|Acidobacteria	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SYD2_k127_3998260_1	234267.Acid_1167	2.919e-177	564.0	COG0304@1|root,COG0304@2|Bacteria,3Y3IS@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SYD2_k127_4016302_0	153721.MYP_2694	5.666e-198	627.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,47KDS@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase family M3	-	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SYD2_k127_4016302_4	1335760.ASTG01000005_gene981	2.767e-47	177.0	2ADQJ@1|root,313FX@2|Bacteria,1MYNR@1224|Proteobacteria,2UCQS@28211|Alphaproteobacteria,2K5ZN@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4016302_3	153721.MYP_1412	1.95e-58	210.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,47NMI@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase Ligase (LigD)	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SYD2_k127_4016302_1	215803.DB30_5220	3.855e-111	366.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2WNK2@28221|Deltaproteobacteria,2YXI1@29|Myxococcales	28221|Deltaproteobacteria	L	Ribonuclease HII	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF208,RNase_HII
SYD2_k127_4016302_5	383372.Rcas_1150	8.508e-06	59.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SYD2_k127_4016302_2	909663.KI867150_gene2720	3.359e-109	367.0	COG0535@1|root,COG0535@2|Bacteria,1Q6NI@1224|Proteobacteria,433FI@68525|delta/epsilon subdivisions,2WXJT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SYD2_k127_4064978_0	204669.Acid345_1010	2.041e-48	180.0	COG0429@1|root,COG0429@2|Bacteria,3Y3MP@57723|Acidobacteria,2JI5X@204432|Acidobacteriia	204432|Acidobacteriia	S	Serine aminopeptidase, S33	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
SYD2_k127_4065898_1	1120746.CCNL01000006_gene373	3.57e-121	398.0	COG4260@1|root,COG4260@2|Bacteria	2|Bacteria	N	virion core protein, lumpy skin disease virus	ydjI	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,SHOCT
SYD2_k127_4065898_0	886293.Sinac_7060	7.45e-145	470.0	COG0304@1|root,COG0304@2|Bacteria,2IWRA@203682|Planctomycetes	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SYD2_k127_4065898_4	404380.Gbem_1026	8.412e-34	139.0	COG0500@1|root,COG2226@2|Bacteria,1QYSR@1224|Proteobacteria,42Z2G@68525|delta/epsilon subdivisions,2WUBA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4065898_3	886293.Sinac_7078	4.984e-42	170.0	COG0644@1|root,COG0644@2|Bacteria,2IZDK@203682|Planctomycetes	203682|Planctomycetes	C	FAD binding domain	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
SYD2_k127_4065898_2	1267534.KB906758_gene2303	1.453e-74	262.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Y@57723|Acidobacteria,2JKVG@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SYD2_k127_4066856_15	1121085.AUCI01000007_gene1169	5.665e-07	55.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,4HDYW@91061|Bacilli,1ZC45@1386|Bacillus	91061|Bacilli	M	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
SYD2_k127_4066856_12	215803.DB30_4430	1.446e-56	206.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2YV5Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.304,1.1.1.47,1.1.1.76	ko:K00034,ko:K03366	ko00030,ko00650,ko01120,ko01200,map00030,map00650,map01120,map01200	-	R01520,R01521,R02855,R02946,R03707,R09078,R10505	RC00066,RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
SYD2_k127_4066856_8	1382359.JIAL01000001_gene3009	1.659e-96	326.0	COG1044@1|root,COG1044@2|Bacteria,3Y2JC@57723|Acidobacteria,2JI2Y@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
SYD2_k127_4066856_1	234267.Acid_0690	2.357e-188	617.0	COG1198@1|root,COG1198@2|Bacteria,3Y2NY@57723|Acidobacteria	57723|Acidobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SYD2_k127_4066856_10	269799.Gmet_2671	8.973e-63	226.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,43TTD@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SYD2_k127_4066856_5	1123250.KB908388_gene205	2.148e-109	369.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4H27H@909932|Negativicutes	909932|Negativicutes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SYD2_k127_4066856_3	1528106.JRJE01000004_gene601	2.115e-162	521.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,2JPVB@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	rkpK	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SYD2_k127_4066856_6	880073.Calab_2000	4.714e-102	341.0	COG0451@1|root,COG0451@2|Bacteria,2NNNX@2323|unclassified Bacteria	2|Bacteria	GM	NAD(P)H-binding	wbpP	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SYD2_k127_4066856_4	204669.Acid345_1390	4.705e-130	427.0	COG1459@1|root,COG1459@2|Bacteria,3Y2X8@57723|Acidobacteria,2JHIX@204432|Acidobacteriia	2|Bacteria	NU	PFAM Type II secretion system F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SYD2_k127_4066856_2	204669.Acid345_1391	2.086e-171	547.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SYD2_k127_4066856_0	1121920.AUAU01000016_gene1339	1.313e-224	710.0	COG2804@1|root,COG2804@2|Bacteria,3Y2IS@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
SYD2_k127_4066856_13	1379270.AUXF01000006_gene164	1.139e-51	190.0	COG1974@1|root,COG1974@2|Bacteria,1ZSSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SYD2_k127_4066856_9	404589.Anae109_2572	4.098e-86	292.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,42ZZ6@68525|delta/epsilon subdivisions,2WV5A@28221|Deltaproteobacteria,2YZAW@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SYD2_k127_4066856_14	234267.Acid_7037	1.53e-46	178.0	COG0468@1|root,COG0468@2|Bacteria,3Y4QB@57723|Acidobacteria	57723|Acidobacteria	L	recA bacterial DNA recombination protein	-	-	-	-	-	-	-	-	-	-	-	-	RecA
SYD2_k127_4066856_7	234267.Acid_7036	6.834e-97	334.0	COG0389@1|root,COG0389@2|Bacteria,3Y3EV@57723|Acidobacteria	57723|Acidobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
SYD2_k127_4066856_11	278963.ATWD01000001_gene1105	7.641e-58	209.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria,2JKQG@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SYD2_k127_4068040_4	56780.SYN_03077	1.01e-23	108.0	COG5652@1|root,COG5652@2|Bacteria,1PUUC@1224|Proteobacteria,43F3B@68525|delta/epsilon subdivisions,2X381@28221|Deltaproteobacteria,2MSC7@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
SYD2_k127_4068040_0	886379.AEWI01000012_gene1130	1.716e-120	400.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,2FM6F@200643|Bacteroidia,3XJH0@558415|Marinilabiliaceae	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SYD2_k127_4068040_1	1192034.CAP_2864	9.387e-91	306.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42NBA@68525|delta/epsilon subdivisions,2X5CP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SYD2_k127_4068040_2	671143.DAMO_3155	8.817e-90	317.0	COG0845@1|root,COG0845@2|Bacteria,2NPBH@2323|unclassified Bacteria	2|Bacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	macA_1	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
SYD2_k127_4068040_5	179408.Osc7112_2507	1.312e-05	54.0	COG3678@1|root,COG3678@2|Bacteria,1G95S@1117|Cyanobacteria,1HD1W@1150|Oscillatoriales	1117|Cyanobacteria	NPTU	PFAM Uncharacterised protein domain Spy-rel	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
SYD2_k127_4068040_3	1403819.BATR01000010_gene390	4.857e-33	135.0	COG1595@1|root,COG1595@2|Bacteria,46STJ@74201|Verrucomicrobia,2IVZ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SYD2_k127_4073666_13	1499967.BAYZ01000088_gene5101	3.027e-14	75.0	COG0305@1|root,COG0305@2|Bacteria,2NNKG@2323|unclassified Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SYD2_k127_4073666_10	278963.ATWD01000001_gene3109	1e-39	157.0	COG0359@1|root,COG0359@2|Bacteria,3Y4MD@57723|Acidobacteria,2JJAN@204432|Acidobacteriia	204432|Acidobacteriia	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SYD2_k127_4073666_11	903818.KI912269_gene342	2.271e-25	108.0	COG0238@1|root,COG0238@2|Bacteria,3Y53K@57723|Acidobacteria	57723|Acidobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SYD2_k127_4073666_12	639030.JHVA01000001_gene2818	4.931e-25	109.0	COG0360@1|root,COG0360@2|Bacteria,3Y50N@57723|Acidobacteria,2JJHP@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SYD2_k127_4073666_7	204669.Acid345_4538	1.057e-51	189.0	COG0193@1|root,COG0193@2|Bacteria,3Y48V@57723|Acidobacteria,2JJ31@204432|Acidobacteriia	204432|Acidobacteriia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SYD2_k127_4073666_8	1267534.KB906758_gene2516	1.595e-47	179.0	COG1825@1|root,COG1825@2|Bacteria,3Y41C@57723|Acidobacteria,2JHW5@204432|Acidobacteriia	204432|Acidobacteriia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SYD2_k127_4073666_3	234267.Acid_7096	2.398e-120	393.0	COG0462@1|root,COG0462@2|Bacteria,3Y3KV@57723|Acidobacteria	57723|Acidobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SYD2_k127_4073666_6	1123239.KB898635_gene2820	2.644e-53	199.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli	91061|Bacilli	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096,M00582	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.29	-	iYO844.BSU00460	GHMP_kinases_C,GHMP_kinases_N
SYD2_k127_4073666_1	293826.Amet_4572	1.54e-152	494.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,36FIQ@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SYD2_k127_4073666_2	234267.Acid_1013	4.062e-149	480.0	COG0468@1|root,COG0468@2|Bacteria,3Y3Y1@57723|Acidobacteria	57723|Acidobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SYD2_k127_4073666_4	204669.Acid345_1160	2.887e-78	269.0	COG0159@1|root,COG0159@2|Bacteria,3Y3X2@57723|Acidobacteria,2JI7C@204432|Acidobacteriia	204432|Acidobacteriia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SYD2_k127_4073666_0	682795.AciX8_4464	3.115e-178	566.0	COG0133@1|root,COG0133@2|Bacteria,3Y45B@57723|Acidobacteria,2JIVM@204432|Acidobacteriia	204432|Acidobacteriia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SYD2_k127_4073666_9	204669.Acid345_1660	4.287e-42	177.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA
SYD2_k127_4073666_5	1267533.KB906738_gene2246	1.226e-65	235.0	COG0608@1|root,COG0608@2|Bacteria,3Y3HI@57723|Acidobacteria,2JICS@204432|Acidobacteriia	204432|Acidobacteriia	L	single-stranded-DNA-specific exonuclease RecJ	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SYD2_k127_4074927_1	1121440.AUMA01000009_gene751	0.0005654	52.0	COG0484@1|root,COG0484@2|Bacteria,1R72H@1224|Proteobacteria,42NCE@68525|delta/epsilon subdivisions,2WKDN@28221|Deltaproteobacteria,2M9A6@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM cytochrome c class III	hmcA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
SYD2_k127_4074927_0	671143.DAMO_0822	8.693e-124	411.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
SYD2_k127_4094515_19	926550.CLDAP_40710	6.21e-05	48.0	2EU9B@1|root,33MRR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4094515_16	1144275.COCOR_02867	1.186e-49	183.0	2CH4Q@1|root,338ZX@2|Bacteria,1QVRN@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
SYD2_k127_4094515_15	1144275.COCOR_02866	3.855e-53	201.0	2C8HC@1|root,33V6K@2|Bacteria,1NVBE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4094515_3	1123261.AXDW01000010_gene339	1.315e-247	781.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,1RQUU@1236|Gammaproteobacteria,1X4D6@135614|Xanthomonadales	135614|Xanthomonadales	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
SYD2_k127_4094515_11	1123261.AXDW01000010_gene340	5.494e-80	268.0	2BECK@1|root,3283Q@2|Bacteria,1RKSC@1224|Proteobacteria,1T14S@1236|Gammaproteobacteria,1X9RS@135614|Xanthomonadales	135614|Xanthomonadales	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
SYD2_k127_4094515_5	1144275.COCOR_02863	4.191e-199	655.0	COG3497@1|root,COG3497@2|Bacteria,1NSAQ@1224|Proteobacteria	1224|Proteobacteria	S	Phage tail sheath protein subtilisin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1C
SYD2_k127_4094515_14	1144275.COCOR_02862	1.781e-57	205.0	2BEKE@1|root,328BU@2|Bacteria,1RM2J@1224|Proteobacteria	1224|Proteobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
SYD2_k127_4094515_13	1144275.COCOR_02861	3.144e-68	241.0	COG1652@1|root,COG1652@2|Bacteria,1NC3Q@1224|Proteobacteria	1224|Proteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SYD2_k127_4094515_8	1144275.COCOR_02859	9.684e-123	402.0	COG3500@1|root,COG3500@2|Bacteria,1R67C@1224|Proteobacteria,4387V@68525|delta/epsilon subdivisions,2X3HN@28221|Deltaproteobacteria,2YW57@29|Myxococcales	28221|Deltaproteobacteria	S	Phage late control gene D protein (GPD)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
SYD2_k127_4094515_7	84531.JMTZ01000038_gene3637	9.63e-124	399.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RZ3X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein and some similarities with VgrG protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
SYD2_k127_4094515_6	261292.Nit79A3_1012	1.719e-125	427.0	28NRK@1|root,332DP@2|Bacteria,1R3A3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4094515_17	1144275.COCOR_02856	4.104e-44	163.0	COG3628@1|root,COG3628@2|Bacteria,1NCAC@1224|Proteobacteria	1224|Proteobacteria	S	GPW gp25 family protein	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
SYD2_k127_4094515_1	1144275.COCOR_02855	1.343e-256	812.0	COG3299@1|root,COG3299@2|Bacteria,1MWKI@1224|Proteobacteria,42Q9A@68525|delta/epsilon subdivisions,2WM4B@28221|Deltaproteobacteria,2YVXE@29|Myxococcales	28221|Deltaproteobacteria	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
SYD2_k127_4094515_2	1144275.COCOR_02854	4.345e-250	805.0	COG4385@1|root,COG4385@2|Bacteria,1NEK3@1224|Proteobacteria,4327R@68525|delta/epsilon subdivisions,2WY5F@28221|Deltaproteobacteria,2YW00@29|Myxococcales	28221|Deltaproteobacteria	S	Phage tail protein (Tail_P2_I)	-	-	-	-	-	-	-	-	-	-	-	-	Tail_P2_I
SYD2_k127_4094515_10	1144275.COCOR_02853	2.434e-92	323.0	2EC0B@1|root,335ZK@2|Bacteria,1N2J2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4094515_12	84531.JMTZ01000038_gene3631	4.699e-72	269.0	2ECCY@1|root,336B7@2|Bacteria,1PJX5@1224|Proteobacteria,1TGYA@1236|Gammaproteobacteria,1X9UH@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4094515_9	1144275.COCOR_02849	1.512e-102	359.0	2DUXF@1|root,33SVE@2|Bacteria,1QY06@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4094515_4	1144275.COCOR_02848	8.56e-212	679.0	COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,43BJ4@68525|delta/epsilon subdivisions,2WMCV@28221|Deltaproteobacteria,2YXIN@29|Myxococcales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SYD2_k127_4094515_0	1123261.AXDW01000010_gene357	2.945e-303	955.0	COG3064@1|root,COG5412@1|root,COG3064@2|Bacteria,COG5412@2|Bacteria,1N710@1224|Proteobacteria,1S7X2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4097449_9	452638.Pnec_1377	1.313e-58	208.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,1K777@119060|Burkholderiaceae	28216|Betaproteobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
SYD2_k127_4097449_0	1266925.JHVX01000001_gene2488	3.633e-300	935.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,3725U@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Cytochrome c-type biogenesis protein CcmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SYD2_k127_4097449_12	498211.CJA_2979	3.389e-23	100.0	COG4115@1|root,COG4115@2|Bacteria,1MZBP@1224|Proteobacteria,1S99Z@1236|Gammaproteobacteria,1FIE7@10|Cellvibrio	1236|Gammaproteobacteria	S	YoeB-like toxin of bacterial type II toxin-antitoxin system	yoeB	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
SYD2_k127_4097449_11	489825.LYNGBM3L_67350	1.883e-24	104.0	COG2161@1|root,COG2161@2|Bacteria,1G8D2@1117|Cyanobacteria,1HCF6@1150|Oscillatoriales	1117|Cyanobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
SYD2_k127_4097449_10	323848.Nmul_A1210	3.021e-54	197.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria,3731F@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
SYD2_k127_4097449_13	261292.Nit79A3_1270	1.088e-12	70.0	COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,2VY1Y@28216|Betaproteobacteria,373N5@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	-	-	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	-	CcmD
SYD2_k127_4097449_3	1266925.JHVX01000001_gene2490	9.468e-107	351.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria,3729C@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SYD2_k127_4097449_5	1266925.JHVX01000001_gene2491	6.033e-82	279.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2VNPU@28216|Betaproteobacteria,371Q1@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SYD2_k127_4097449_8	1266925.JHVX01000001_gene2492	1.938e-59	213.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2VMGA@28216|Betaproteobacteria,372UK@32003|Nitrosomonadales	28216|Betaproteobacteria	P	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
SYD2_k127_4097449_14	330214.NIDE0059	2.762e-12	72.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3J1E4@40117|Nitrospirae	40117|Nitrospirae	P	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	Rhodanese,SNARE_assoc
SYD2_k127_4097449_4	1267533.KB906737_gene1940	2.804e-84	296.0	COG3488@1|root,COG3488@2|Bacteria,3Y3DB@57723|Acidobacteria,2JK0S@204432|Acidobacteriia	204432|Acidobacteriia	C	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
SYD2_k127_4097449_15	713586.KB900536_gene178	1.096e-11	68.0	COG3118@1|root,COG3118@2|Bacteria,1NIQX@1224|Proteobacteria	1224|Proteobacteria	O	Glutaredoxin-like domain (DUF836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
SYD2_k127_4097449_7	234267.Acid_4388	2.514e-63	224.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	-	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
SYD2_k127_4097449_1	234267.Acid_4387	8.632e-147	469.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
SYD2_k127_4097449_2	234267.Acid_4386	4.548e-131	428.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
SYD2_k127_4097449_6	234267.Acid_4385	5.616e-77	271.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,PA14
SYD2_k127_4116464_12	243274.THEMA_06325	1.495e-09	70.0	COG0366@1|root,COG1075@1|root,COG1716@1|root,COG0366@2|Bacteria,COG1075@2|Bacteria,COG1716@2|Bacteria,2GDJT@200918|Thermotogae	200918|Thermotogae	T	peptidase C11 clostripain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
SYD2_k127_4116464_3	56107.Cylst_2375	2.088e-133	466.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1HK1F@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_1,TPR_12,TPR_7,TPR_8
SYD2_k127_4116464_9	555779.Dthio_PD0143	5.112e-40	152.0	2DPSP@1|root,33387@2|Bacteria	2|Bacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SYD2_k127_4116464_10	347834.RHE_CH01153	2.073e-14	79.0	COG4244@1|root,COG4244@2|Bacteria,1RKBB@1224|Proteobacteria,2UA11@28211|Alphaproteobacteria,4BFTR@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SYD2_k127_4116464_2	204669.Acid345_3257	2.226e-137	451.0	COG4867@1|root,COG4867@2|Bacteria,3Y2VU@57723|Acidobacteria,2JHSR@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
SYD2_k127_4116464_8	1210884.HG799464_gene10700	1.959e-40	154.0	COG0614@1|root,COG0614@2|Bacteria,2J0J0@203682|Planctomycetes	203682|Planctomycetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
SYD2_k127_4116464_0	379066.GAU_0593	2.375e-187	597.0	COG1239@1|root,COG1239@2|Bacteria,1ZT0R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
SYD2_k127_4116464_4	1242864.D187_000461	5.296e-107	364.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,430H1@68525|delta/epsilon subdivisions,2WVZX@28221|Deltaproteobacteria,2YUWZ@29|Myxococcales	28221|Deltaproteobacteria	L	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,NUDIX
SYD2_k127_4116464_5	530564.Psta_0515	7.224e-88	295.0	COG2041@1|root,COG2041@2|Bacteria,2IYS5@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase, molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SYD2_k127_4116464_11	1144312.PMI09_02939	2.005e-12	74.0	COG0664@1|root,COG0664@2|Bacteria,1RI6M@1224|Proteobacteria,2U9WH@28211|Alphaproteobacteria,4B9V7@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SYD2_k127_4116464_7	1210884.HG799465_gene12237	2.079e-46	169.0	COG0662@1|root,COG0662@2|Bacteria,2J42S@203682|Planctomycetes	203682|Planctomycetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SYD2_k127_4116464_1	215803.DB30_7179	2.641e-150	483.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,42YQP@68525|delta/epsilon subdivisions,2WTJM@28221|Deltaproteobacteria,2YY5X@29|Myxococcales	28221|Deltaproteobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SYD2_k127_4181777_13	1123376.AUIU01000003_gene1639	5.043e-31	128.0	COG4974@1|root,COG4974@2|Bacteria,3J1FQ@40117|Nitrospirae	40117|Nitrospirae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SYD2_k127_4181777_15	240015.ACP_2017	3.843e-28	121.0	COG0789@1|root,COG0789@2|Bacteria,3Y56I@57723|Acidobacteria,2JJNQ@204432|Acidobacteriia	204432|Acidobacteriia	K	Regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SYD2_k127_4181777_3	1382359.JIAL01000001_gene1153	2.828e-147	477.0	COG0436@1|root,COG0436@2|Bacteria,3Y64P@57723|Acidobacteria,2JMB5@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SYD2_k127_4181777_9	671143.DAMO_2184	9.219e-56	211.0	COG0611@1|root,COG0611@2|Bacteria,2NP8J@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.16	ko:K00946,ko:K07123	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2977c,iSFV_1184.SFV_0382,iYO844.BSU05900	AIRS,AIRS_C
SYD2_k127_4181777_11	82654.Pse7367_3259	3.512e-33	137.0	COG1876@1|root,COG3409@1|root,COG1876@2|Bacteria,COG3409@2|Bacteria,1G4XP@1117|Cyanobacteria	1117|Cyanobacteria	M	Peptidase M15B M15C, D,D-carboxypeptidase VanY endolysins	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,VanY
SYD2_k127_4181777_0	580332.Slit_1091	0.0	1049.0	COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,2VJSS@28216|Betaproteobacteria,44VXZ@713636|Nitrosomonadales	28216|Betaproteobacteria	L	type III restriction protein res subunit	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
SYD2_k127_4181777_16	526222.Desal_1663	5.223e-24	105.0	2DCBI@1|root,2ZDJD@2|Bacteria,1NBWB@1224|Proteobacteria,432RQ@68525|delta/epsilon subdivisions,2WY9R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4181777_1	1191523.MROS_0122	2.347e-220	700.0	COG0286@1|root,COG0732@1|root,COG0286@2|Bacteria,COG0732@2|Bacteria	2|Bacteria	V	type I restriction modification DNA specificity domain	-	-	2.1.1.72,3.1.21.3	ko:K01154,ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,Methylase_S,N6_Mtase
SYD2_k127_4181777_6	933262.AXAM01000049_gene3260	2.725e-83	281.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42RB7@68525|delta/epsilon subdivisions,2WN5V@28221|Deltaproteobacteria,2MJQK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	RadC-like JAB domain	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SYD2_k127_4181777_20	1116472.MGMO_83c00120	5.173e-08	64.0	2CCDM@1|root,2Z9YZ@2|Bacteria,1R8JF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4181777_4	1379698.RBG1_1C00001G0844	1.537e-144	472.0	COG0215@1|root,COG0215@2|Bacteria,2NNP0@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECUMN_1333.ECUMN_0566,iJN746.PP_2905,iNJ661.Rv2130c	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SYD2_k127_4181777_7	1125863.JAFN01000001_gene1580	4.523e-75	265.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
SYD2_k127_4181777_14	751944.HALDL1_10980	3.172e-29	128.0	COG0451@1|root,arCOG01369@2157|Archaea,2Y7SY@28890|Euryarchaeota,23SBI@183963|Halobacteria	183963|Halobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SYD2_k127_4181777_8	330214.NIDE3031	1.018e-74	264.0	COG0241@1|root,COG0859@1|root,COG0241@2|Bacteria,COG0859@2|Bacteria,3J0PZ@40117|Nitrospirae	40117|Nitrospirae	EM	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Hydrolase_like
SYD2_k127_4181777_10	861299.J421_3339	6.401e-45	169.0	COG2020@1|root,COG2020@2|Bacteria,1ZU79@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SYD2_k127_4181777_18	278963.ATWD01000001_gene1874	3.938e-14	82.0	2DBU8@1|root,2ZB4S@2|Bacteria,3Y31B@57723|Acidobacteria,2JIT7@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SYD2_k127_4181777_12	720554.Clocl_2100	1.793e-32	137.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,3WIKJ@541000|Ruminococcaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SYD2_k127_4181777_2	459349.CLOAM0423	6.861e-213	668.0	COG1260@1|root,COG1260@2|Bacteria,2NP2I@2323|unclassified Bacteria	2|Bacteria	I	Myo-inositol-1-phosphate synthase	ino1	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
SYD2_k127_4181777_5	204669.Acid345_0710	1.798e-139	454.0	COG0542@1|root,COG0542@2|Bacteria,3Y463@57723|Acidobacteria,2JMAK@204432|Acidobacteriia	204432|Acidobacteriia	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
SYD2_k127_4181777_19	1173024.KI912152_gene597	5.393e-09	67.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G2R4@1117|Cyanobacteria	1117|Cyanobacteria	CT	PFAM PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
SYD2_k127_4181777_17	1382304.JNIL01000001_gene899	2.973e-14	83.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,2792X@186823|Alicyclobacillaceae	91061|Bacilli	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SYD2_k127_4190728_3	1124982.MSI_23740	3.585e-15	75.0	COG0254@1|root,COG0254@2|Bacteria,2J93Z@203691|Spirochaetes	203691|Spirochaetes	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SYD2_k127_4190728_1	1340493.JNIF01000004_gene264	7.329e-67	244.0	COG3872@1|root,COG3872@2|Bacteria,3Y66K@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SYD2_k127_4190728_2	1380600.AUYN01000001_gene2754	3.588e-50	184.0	2DQUP@1|root,338SW@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4145)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4145
SYD2_k127_4190728_0	240015.ACP_2651	6.126e-151	484.0	COG0216@1|root,COG0216@2|Bacteria,3Y2N9@57723|Acidobacteria,2JHYH@204432|Acidobacteriia	204432|Acidobacteriia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SYD2_k127_4196411_0	666684.AfiDRAFT_0684	4.209e-32	133.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,dCache_1
SYD2_k127_4196411_1	316055.RPE_3610	5.189e-29	122.0	COG0797@1|root,COG1525@1|root,COG0797@2|Bacteria,COG1525@2|Bacteria,1N145@1224|Proteobacteria,2UCUE@28211|Alphaproteobacteria,3K53S@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	LM	Rare lipoprotein A	-	-	-	-	-	-	-	-	-	-	-	-	DPBB_1,SNase
SYD2_k127_4196411_2	883078.HMPREF9695_03211	1.203e-28	118.0	COG0633@1|root,COG2114@1|root,COG0633@2|Bacteria,COG2114@2|Bacteria,1N5XC@1224|Proteobacteria,2TRGX@28211|Alphaproteobacteria,3JQU2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CT	Adenylyl- / guanylyl cyclase, catalytic domain	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Guanylate_cyc
SYD2_k127_4202116_0	1173022.Cri9333_0579	4.794e-134	448.0	COG1353@1|root,COG1353@2|Bacteria,1G295@1117|Cyanobacteria,1HAGH@1150|Oscillatoriales	1117|Cyanobacteria	S	crispr-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4202116_1	1173022.Cri9333_0580	1.311e-67	238.0	COG1337@1|root,COG1337@2|Bacteria,1G2GV@1117|Cyanobacteria,1HA95@1150|Oscillatoriales	1117|Cyanobacteria	L	RAMP superfamily	-	-	-	ko:K19134	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
SYD2_k127_4206561_0	1267535.KB906767_gene2094	9.052e-233	732.0	COG1131@1|root,COG1131@2|Bacteria,3Y3VU@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SYD2_k127_4206561_1	1267535.KB906767_gene2093	1.226e-108	362.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
SYD2_k127_4206561_2	1267535.KB906767_gene2092	4.207e-105	354.0	COG0842@1|root,COG0842@2|Bacteria,3Y73W@57723|Acidobacteria	57723|Acidobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SYD2_k127_4206561_4	1226322.HMPREF1545_03748	2.568e-07	62.0	COG3568@1|root,COG3568@2|Bacteria,1UE9D@1239|Firmicutes,25J4Q@186801|Clostridia,2N7ZC@216572|Oscillospiraceae	186801|Clostridia	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SYD2_k127_4206561_3	861299.J421_2943	6.318e-19	90.0	COG1234@1|root,COG1234@2|Bacteria,1ZT5E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SYD2_k127_4215479_2	234267.Acid_5217	1.958e-31	130.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SYD2_k127_4215479_1	502025.Hoch_1576	5.892e-68	235.0	COG1595@1|root,COG1595@2|Bacteria,1RINW@1224|Proteobacteria,4385N@68525|delta/epsilon subdivisions,2X3FI@28221|Deltaproteobacteria,2YVVV@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SYD2_k127_4215479_0	56780.SYN_00886	4.751e-94	321.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria,2MQH8@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Phosphofructokinase	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SYD2_k127_4277031_5	1075090.GOAMR_43_00620	3.388e-07	51.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	yndB	-	3.1.1.45	ko:K01061,ko:K11750	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_5,DLH,DUF1100,DUF3530
SYD2_k127_4277031_1	1121286.AUMT01000011_gene2303	2.311e-49	184.0	COG4461@1|root,COG4461@2|Bacteria,4NK5M@976|Bacteroidetes,1I16D@117743|Flavobacteriia,3ZRW5@59732|Chryseobacterium	976|Bacteroidetes	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4277031_3	1267535.KB906767_gene291	8.768e-24	104.0	COG1193@1|root,COG1193@2|Bacteria,3Y8PZ@57723|Acidobacteria	57723|Acidobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
SYD2_k127_4277031_2	292459.STH3176	3.366e-47	177.0	COG2009@1|root,COG2009@2|Bacteria,1TQUI@1239|Firmicutes,24M03@186801|Clostridia	186801|Clostridia	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SYD2_k127_4277031_0	562970.Btus_0636	5.087e-280	871.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HBVG@91061|Bacilli,277ZQ@186823|Alicyclobacillaceae	91061|Bacilli	C	SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SYD2_k127_4277031_4	1033740.CAEW01000016_gene2926	2.084e-12	67.0	COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,4HAG7@91061|Bacilli,26DDG@186818|Planococcaceae	91061|Bacilli	C	COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit	sdhB	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0055114,GO:0071944	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
SYD2_k127_4279750_1	1121920.AUAU01000010_gene50	1.859e-161	520.0	COG0624@1|root,COG0624@2|Bacteria,3Y3TZ@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SYD2_k127_4279750_2	1173020.Cha6605_2960	4.707e-43	162.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SYD2_k127_4279750_0	886293.Sinac_4730	0.0	1347.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SYD2_k127_4279750_3	926569.ANT_06890	4.458e-09	61.0	2ECEX@1|root,336D4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4282948_0	234267.Acid_2647	0.0	1373.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,3Y6ZR@57723|Acidobacteria	57723|Acidobacteria	M	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SYD2_k127_4282948_1	234267.Acid_2646	1.771e-05	48.0	COG2834@1|root,COG2834@2|Bacteria,3Y7NW@57723|Acidobacteria	57723|Acidobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4283320_4	1297742.A176_05793	8.439e-47	173.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria	1224|Proteobacteria	S	3-Demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SYD2_k127_4283320_10	397945.Aave_0972	1.691e-07	59.0	28VXR@1|root,2ZHZ1@2|Bacteria,1PB7W@1224|Proteobacteria,2W5E9@28216|Betaproteobacteria,4AIRS@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4283320_9	1122915.AUGY01000001_gene7114	5.878e-16	83.0	COG2318@1|root,COG2318@2|Bacteria,1VI69@1239|Firmicutes,4HPG9@91061|Bacilli,26TJI@186822|Paenibacillaceae	91061|Bacilli	S	DinB superfamily	ywlC1	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
SYD2_k127_4283320_12	1267533.KB906740_gene263	0.0002902	47.0	COG1917@1|root,COG1917@2|Bacteria,3Y94I@57723|Acidobacteria,2JNYP@204432|Acidobacteriia	204432|Acidobacteriia	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4283320_5	1267533.KB906740_gene263	5.778e-42	156.0	COG1917@1|root,COG1917@2|Bacteria,3Y94I@57723|Acidobacteria,2JNYP@204432|Acidobacteriia	204432|Acidobacteriia	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4283320_11	1123073.KB899243_gene504	3.236e-07	58.0	2AEZN@1|root,314XR@2|Bacteria,1NSHG@1224|Proteobacteria,1SMR4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4283320_7	582515.KR51_00025710	7.797e-20	92.0	2EUSR@1|root,33N8A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4283320_6	1094184.KWO_0116985	5.769e-41	158.0	COG1278@1|root,COG3326@1|root,COG1278@2|Bacteria,COG3326@2|Bacteria,1N6YM@1224|Proteobacteria,1SCMX@1236|Gammaproteobacteria,1X72J@135614|Xanthomonadales	135614|Xanthomonadales	K	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	CSD,DUF1294
SYD2_k127_4283320_8	443143.GM18_4182	7.652e-17	93.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1PEH7@1224|Proteobacteria,42TVC@68525|delta/epsilon subdivisions,2WUUP@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	M	Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8
SYD2_k127_4283320_3	272560.BPSL1370	1.531e-48	180.0	COG0406@1|root,COG0406@2|Bacteria,1RH8P@1224|Proteobacteria,2VUH5@28216|Betaproteobacteria,1K8ZG@119060|Burkholderiaceae	28216|Betaproteobacteria	G	alpha-ribazole phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4283320_0	1123242.JH636434_gene5497	1.174e-197	637.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2IXK8@203682|Planctomycetes	203682|Planctomycetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SYD2_k127_4283320_1	247490.KSU1_B0364	2.685e-63	241.0	COG4191@1|root,COG4191@2|Bacteria,2J2BM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SYD2_k127_4283320_2	207954.MED92_04959	4.826e-57	207.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XH6F@135619|Oceanospirillales	135619|Oceanospirillales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K10126	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SYD2_k127_4287680_2	1128421.JAGA01000003_gene2872	1.203e-55	198.0	COG2010@1|root,COG2010@2|Bacteria,2NPSE@2323|unclassified Bacteria	2|Bacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
SYD2_k127_4287680_1	1128421.JAGA01000003_gene2871	6.15e-212	668.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
SYD2_k127_4287680_0	234267.Acid_0490	0.0	1049.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,3Y2Z0@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
SYD2_k127_4291552_4	234267.Acid_5271	1.412e-09	61.0	COG1917@1|root,COG1917@2|Bacteria,3Y4Y3@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SYD2_k127_4291552_3	1340493.JNIF01000003_gene2685	5.412e-73	255.0	COG1475@1|root,COG1475@2|Bacteria,3Y40Y@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SYD2_k127_4291552_1	1430331.EP10_00955	1.499e-88	300.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,1WF4W@129337|Geobacillus	91061|Bacilli	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SYD2_k127_4291552_0	240015.ACP_2349	5.506e-214	683.0	COG0445@1|root,COG0445@2|Bacteria,3Y3E4@57723|Acidobacteria,2JHP3@204432|Acidobacteriia	204432|Acidobacteriia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
SYD2_k127_4291552_2	1382359.JIAL01000001_gene1535	9.302e-79	274.0	COG0486@1|root,COG0486@2|Bacteria,3Y3QJ@57723|Acidobacteria,2JHNN@204432|Acidobacteriia	204432|Acidobacteriia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
SYD2_k127_4304413_1	398720.MED217_08240	1.679e-87	302.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1HY2V@117743|Flavobacteriia	976|Bacteroidetes	Q	Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SYD2_k127_4304413_0	234267.Acid_1582	0.0	1054.0	COG2936@1|root,COG2936@2|Bacteria,3Y684@57723|Acidobacteria	57723|Acidobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SYD2_k127_4304413_2	204669.Acid345_3936	8.059e-72	248.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SYD2_k127_4310012_10	216142.LT40_17965	8.418e-45	169.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RPMN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	lipopolysaccharide heptosyltransferase I	rfaC	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	iB21_1397.B21_03429,iECBD_1354.ECBD_0105,iECB_1328.ECB_03478,iECD_1391.ECD_03478,iECNA114_1301.ECNA114_3774,iECSF_1327.ECSF_3456,iSF_1195.SF3661,iS_1188.S4107	Glyco_transf_9
SYD2_k127_4310012_4	469383.Cwoe_1095	4.606e-111	367.0	COG0524@1|root,COG0524@2|Bacteria,2HPJD@201174|Actinobacteria,4CQWU@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SYD2_k127_4310012_16	641143.HMPREF9331_01561	9.374e-05	51.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1HYEQ@117743|Flavobacteriia,1EQ8H@1016|Capnocytophaga	976|Bacteroidetes	S	outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
SYD2_k127_4310012_2	1267535.KB906767_gene5475	1.083e-119	390.0	COG0005@1|root,COG0005@2|Bacteria,3Y2MA@57723|Acidobacteria,2JI5Q@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SYD2_k127_4310012_15	290397.Adeh_2374	6.684e-11	71.0	2ER1F@1|root,33IKZ@2|Bacteria,1PANM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4310012_7	869210.Marky_1204	3.259e-69	245.0	COG0491@1|root,COG0491@2|Bacteria,1WISH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SYD2_k127_4310012_14	1476973.JMMB01000007_gene3240	9.095e-29	131.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,24C7H@186801|Clostridia,25UIJ@186804|Peptostreptococcaceae	186801|Clostridia	M	SurA N-terminal domain	prsA	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SYD2_k127_4310012_12	891968.Anamo_2043	2.379e-41	156.0	COG0346@1|root,COG0346@2|Bacteria,3TAXT@508458|Synergistetes	508458|Synergistetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SYD2_k127_4310012_5	204669.Acid345_2365	2.506e-89	307.0	COG1703@1|root,COG1703@2|Bacteria,3Y40X@57723|Acidobacteria,2JHW8@204432|Acidobacteriia	204432|Acidobacteriia	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SYD2_k127_4310012_0	204669.Acid345_2369	1.144e-162	520.0	COG1960@1|root,COG1960@2|Bacteria,3Y3T6@57723|Acidobacteria,2JIV6@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SYD2_k127_4310012_8	330214.NIDE1423	2.486e-67	237.0	COG1187@1|root,COG1187@2|Bacteria,3J0RN@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.21,5.4.99.22	ko:K06178,ko:K06181,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SYD2_k127_4310012_9	1267535.KB906767_gene5272	8.092e-55	198.0	COG1386@1|root,COG1386@2|Bacteria,3Y3E0@57723|Acidobacteria,2JHVE@204432|Acidobacteriia	204432|Acidobacteriia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SYD2_k127_4310012_11	696369.KI912183_gene1310	2.49e-44	171.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,2613X@186807|Peptococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SYD2_k127_4310012_3	555079.Toce_0260	1.333e-114	377.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,42EWC@68295|Thermoanaerobacterales	186801|Clostridia	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SYD2_k127_4310012_13	401053.AciPR4_3282	2.837e-40	157.0	COG1994@1|root,COG1994@2|Bacteria,3Y58P@57723|Acidobacteria,2JJUI@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SYD2_k127_4310012_6	1382359.JIAL01000001_gene2793	7.302e-84	291.0	COG2133@1|root,COG2133@2|Bacteria,3Y98P@57723|Acidobacteria,2JP56@204432|Acidobacteriia	204432|Acidobacteriia	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4310012_1	667014.Thein_0206	1.097e-127	419.0	COG2262@1|root,COG2262@2|Bacteria,2GH9H@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SYD2_k127_4316739_1	264198.Reut_A1226	0.0002677	44.0	COG2823@1|root,COG2823@2|Bacteria,1RA8T@1224|Proteobacteria,2VRH6@28216|Betaproteobacteria,1K1XG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	SMART Transport-associated and nodulation region	-	-	-	-	-	-	-	-	-	-	-	-	BON
SYD2_k127_4316739_0	338963.Pcar_0896	3.226e-179	593.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,43UAW@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Cation transporter/ATPase, N-terminus	pacL	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SYD2_k127_4332770_1	204669.Acid345_0395	1.618e-183	621.0	COG1629@1|root,COG4771@2|Bacteria,3Y2GB@57723|Acidobacteria,2JP02@204432|Acidobacteriia	204432|Acidobacteriia	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SYD2_k127_4332770_5	1267535.KB906767_gene5053	1.007e-75	268.0	COG2367@1|root,COG2367@2|Bacteria,3Y3UF@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SYD2_k127_4332770_2	269799.Gmet_0138	7.884e-142	464.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,42QA4@68525|delta/epsilon subdivisions,2WKD1@28221|Deltaproteobacteria,43SDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
SYD2_k127_4332770_14	292415.Tbd_1642	7.169e-06	55.0	COG2823@1|root,COG2823@2|Bacteria,1NIM8@1224|Proteobacteria,2VX5E@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SMART Transport-associated and nodulation	-	-	-	-	-	-	-	-	-	-	-	-	BON
SYD2_k127_4332770_11	401053.AciPR4_0722	2.485e-35	154.0	COG0457@1|root,COG0457@2|Bacteria,3Y2VC@57723|Acidobacteria,2JHR2@204432|Acidobacteriia	204432|Acidobacteriia	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
SYD2_k127_4332770_10	1123376.AUIU01000013_gene1724	2.221e-62	237.0	COG0815@1|root,COG0815@2|Bacteria,3J0HA@40117|Nitrospirae	40117|Nitrospirae	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SYD2_k127_4332770_3	1267535.KB906767_gene4419	1.755e-126	413.0	COG1186@1|root,COG1186@2|Bacteria,3Y2ZM@57723|Acidobacteria,2JIGW@204432|Acidobacteriia	204432|Acidobacteriia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SYD2_k127_4332770_0	1267535.KB906767_gene1053	6.359e-198	645.0	COG1674@1|root,COG1674@2|Bacteria,3Y3CJ@57723|Acidobacteria,2JHRN@204432|Acidobacteriia	204432|Acidobacteriia	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SYD2_k127_4332770_13	760568.Desku_2741	6.968e-15	78.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,262CC@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM Competence protein ComEA, helix-hairpin-helix	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SYD2_k127_4332770_6	1382359.JIAL01000001_gene2277	2.154e-74	268.0	COG2379@1|root,COG2379@2|Bacteria,3Y2XC@57723|Acidobacteria,2JID2@204432|Acidobacteriia	204432|Acidobacteriia	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
SYD2_k127_4332770_12	243365.CV_3182	3.102e-22	104.0	COG5553@1|root,COG5553@2|Bacteria,1NXEP@1224|Proteobacteria	1224|Proteobacteria	C	Cysteine dioxygenase type I	-	-	1.13.11.20	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	-	R00893	RC00404	ko00000,ko00001,ko01000	-	-	-	CDO_I
SYD2_k127_4332770_4	1267535.KB906767_gene3797	2.69e-77	289.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,3Y3VQ@57723|Acidobacteria,2JI41@204432|Acidobacteriia	204432|Acidobacteriia	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SYD2_k127_4332770_7	234267.Acid_5841	1.537e-64	237.0	COG2265@1|root,COG2265@2|Bacteria,3Y3SF@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SYD2_k127_4332770_8	1245469.S58_17850	1.678e-64	237.0	COG2333@1|root,COG2333@2|Bacteria,1RBYH@1224|Proteobacteria,2U6NT@28211|Alphaproteobacteria,3K1MG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SYD2_k127_4332770_9	114615.BRADO1557	1.624e-63	230.0	COG3590@1|root,COG3590@2|Bacteria,1QQ5Q@1224|Proteobacteria,2TVBZ@28211|Alphaproteobacteria,3JXR2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4344122_15	338966.Ppro_2663	3.245e-25	112.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42W7K@68525|delta/epsilon subdivisions,2WRU7@28221|Deltaproteobacteria,43VUJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SYD2_k127_4344122_19	671143.DAMO_3157	6.365e-13	74.0	28VYX@1|root,2ZI05@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4344122_12	1382359.JIAL01000001_gene2077	2.534e-47	186.0	COG0250@1|root,COG0250@2|Bacteria,3Y3I1@57723|Acidobacteria,2JHYX@204432|Acidobacteriia	204432|Acidobacteriia	K	Participates in transcription elongation, termination and antitermination	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4344122_1	1340493.JNIF01000003_gene3519	1.375e-208	686.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SYD2_k127_4344122_20	1303518.CCALI_01139	0.0001015	53.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SYD2_k127_4344122_10	251229.Chro_0372	1.327e-59	223.0	COG1361@1|root,COG2931@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1GQTI@1117|Cyanobacteria,3VN50@52604|Pleurocapsales	1117|Cyanobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
SYD2_k127_4344122_6	1120977.JHUX01000005_gene2686	4.527e-89	336.0	COG1470@1|root,COG3188@1|root,COG1470@2|Bacteria,COG3188@2|Bacteria,1QV71@1224|Proteobacteria,1RYEJ@1236|Gammaproteobacteria,3NJPH@468|Moraxellaceae	1236|Gammaproteobacteria	NU	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF11,OmpA,SdrD_B
SYD2_k127_4344122_16	1112216.JH594425_gene1761	7.048e-22	114.0	COG1361@1|root,COG1361@2|Bacteria,1QYI1@1224|Proteobacteria,2TXRW@28211|Alphaproteobacteria,2KEJ6@204457|Sphingomonadales	204457|Sphingomonadales	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4344122_11	1229172.JQFA01000002_gene3172	3.824e-55	218.0	COG4964@1|root,COG4964@2|Bacteria,1G3U8@1117|Cyanobacteria,1H8H0@1150|Oscillatoriales	1117|Cyanobacteria	U	Belongs to the GSP D family	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4344122_17	489825.LYNGBM3L_37780	1.42e-19	96.0	COG4719@1|root,COG4719@2|Bacteria,1G6YW@1117|Cyanobacteria,1HC00@1150|Oscillatoriales	1117|Cyanobacteria	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
SYD2_k127_4344122_4	56780.SYN_01093	1.592e-105	359.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MRFN@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SYD2_k127_4344122_14	338963.Pcar_0258	2.444e-42	174.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WME7@28221|Deltaproteobacteria,43SCJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	hsfB	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
SYD2_k127_4344122_3	1267535.KB906767_gene4678	1.241e-106	359.0	COG1092@1|root,COG1092@2|Bacteria,3Y2PV@57723|Acidobacteria,2JICM@204432|Acidobacteriia	204432|Acidobacteriia	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
SYD2_k127_4344122_0	234267.Acid_3204	2.238e-301	956.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
SYD2_k127_4344122_13	204669.Acid345_0581	6.372e-46	173.0	COG1974@1|root,COG1974@2|Bacteria,3Y47Z@57723|Acidobacteria,2JIJ3@204432|Acidobacteriia	204432|Acidobacteriia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SYD2_k127_4344122_5	765952.PUV_10690	8.176e-94	319.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria	2|Bacteria	L	DNA ligase (ATP) activity	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SYD2_k127_4344122_8	1128421.JAGA01000002_gene1139	2.34e-72	248.0	COG3663@1|root,COG3663@2|Bacteria,2NRDF@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	mug	GO:0000700,GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008263,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.28,6.3.3.2	ko:K01934,ko:K03649	ko00670,ko01100,ko03410,map00670,map01100,map03410	-	R02301	RC00183	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SYD2_k127_4344122_9	204669.Acid345_2716	4.577e-66	256.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SYD2_k127_4344122_18	240015.ACP_3504	4.397e-18	86.0	2E328@1|root,32Y2G@2|Bacteria,3Y5U5@57723|Acidobacteria,2JK3Y@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4344122_7	234267.Acid_2024	4.403e-86	291.0	COG1801@1|root,COG1801@2|Bacteria,3Y2WS@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SYD2_k127_4344122_2	1382359.JIAL01000001_gene1484	1.895e-177	573.0	COG0210@1|root,COG0210@2|Bacteria,3Y2W8@57723|Acidobacteria,2JIDH@204432|Acidobacteriia	204432|Acidobacteriia	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SYD2_k127_4362627_2	1267535.KB906767_gene2727	1.881e-148	474.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria,2JIV1@204432|Acidobacteriia	204432|Acidobacteriia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SYD2_k127_4362627_9	1382359.JIAL01000001_gene1679	9.026e-39	147.0	COG0234@1|root,COG0234@2|Bacteria,3Y4VQ@57723|Acidobacteria,2JJEF@204432|Acidobacteriia	204432|Acidobacteriia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SYD2_k127_4362627_7	1123258.AQXZ01000018_gene1121	2.527e-58	215.0	COG1404@1|root,COG1404@2|Bacteria,2IRXR@201174|Actinobacteria,4FZ50@85025|Nocardiaceae	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SYD2_k127_4362627_13	1125863.JAFN01000001_gene381	8.723e-12	76.0	COG2199@1|root,COG3706@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP
SYD2_k127_4362627_10	1370125.AUWT01000032_gene1637	4.262e-34	142.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SYD2_k127_4362627_0	710685.MycrhN_1487	1.277e-196	638.0	COG1132@1|root,COG1132@2|Bacteria,2GUVF@201174|Actinobacteria,236TF@1762|Mycobacteriaceae	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SYD2_k127_4362627_1	234267.Acid_1040	2.784e-196	632.0	COG1199@1|root,COG1199@2|Bacteria,3Y3DN@57723|Acidobacteria	57723|Acidobacteria	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2
SYD2_k127_4362627_11	335543.Sfum_0003	8.321e-34	134.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,42TJ5@68525|delta/epsilon subdivisions,2WQ2Z@28221|Deltaproteobacteria,2MRZN@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PFAM 6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SYD2_k127_4362627_3	1125863.JAFN01000001_gene1446	4.429e-117	392.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SYD2_k127_4362627_16	246197.MXAN_1129	0.0003226	51.0	COG3852@1|root,COG3852@2|Bacteria,1QVPN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,HisKA_7TM,PAS_4,PAS_8
SYD2_k127_4362627_12	383372.Rcas_4302	3.661e-29	120.0	COG2199@1|root,COG3706@2|Bacteria,2GAEA@200795|Chloroflexi,375RZ@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SYD2_k127_4362627_15	396595.TK90_0534	5.728e-11	68.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T44K@1236|Gammaproteobacteria,1WXW4@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
SYD2_k127_4362627_6	211165.AJLN01000153_gene671	2.28e-76	261.0	COG0500@1|root,COG2226@2|Bacteria,1GAXU@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SYD2_k127_4362627_14	1227453.C444_19652	4.377e-11	73.0	COG0500@1|root,arCOG01773@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SYD2_k127_4362627_5	1278073.MYSTI_06338	2.835e-81	279.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,2YY1K@29|Myxococcales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
SYD2_k127_4362627_8	1379270.AUXF01000002_gene1539	2.795e-49	181.0	2C7E0@1|root,330TX@2|Bacteria,1ZUQG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4362627_4	358220.C380_04965	1.101e-89	302.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2VIGI@28216|Betaproteobacteria,4A9XQ@80864|Comamonadaceae	28216|Betaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SYD2_k127_4378781_1	306281.AJLK01000013_gene4884	1.378e-150	531.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1GCJ1@1117|Cyanobacteria,1JJFJ@1189|Stigonemataceae	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
SYD2_k127_4378781_5	452637.Oter_4105	5.19e-77	262.0	COG2818@1|root,COG2818@2|Bacteria,46VJV@74201|Verrucomicrobia,3K9KD@414999|Opitutae	414999|Opitutae	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SYD2_k127_4378781_4	1089548.KI783301_gene27	2.034e-94	312.0	28H95@1|root,2Z7KY@2|Bacteria,1TQTR@1239|Firmicutes,4HB82@91061|Bacilli,3WFJR@539002|Bacillales incertae sedis	91061|Bacilli	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
SYD2_k127_4378781_2	313606.M23134_04775	2.983e-105	360.0	COG1680@1|root,COG1680@2|Bacteria,4NKJT@976|Bacteroidetes,47X9X@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SYD2_k127_4378781_6	1254432.SCE1572_25505	1.865e-67	231.0	COG0346@1|root,COG0346@2|Bacteria,1RE6F@1224|Proteobacteria	1224|Proteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SYD2_k127_4378781_13	1521187.JPIM01000127_gene252	2.14e-08	55.0	COG0626@1|root,COG0626@2|Bacteria,2G5M2@200795|Chloroflexi,3764B@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SYD2_k127_4378781_10	102125.Xen7305DRAFT_00036860	2.655e-18	86.0	2C6B2@1|root,335GA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4378781_8	1174528.JH992898_gene4370	1.147e-27	114.0	COG2929@1|root,COG2929@2|Bacteria,1GKP2@1117|Cyanobacteria,1JMH9@1189|Stigonemataceae	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
SYD2_k127_4378781_11	204669.Acid345_3466	1.23e-17	86.0	2DS5Y@1|root,33EPX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4378781_9	111781.Lepto7376_2071	8.137e-22	101.0	2E8II@1|root,332WK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4378781_15	1120949.KB903322_gene2797	0.0004857	43.0	COG2764@1|root,COG2764@2|Bacteria,2IKRR@201174|Actinobacteria,4DJ1Q@85008|Micromonosporales	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SYD2_k127_4378781_3	1312954.KI914890_gene2171	1.322e-96	319.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,1W9UJ@1268|Micrococcaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SYD2_k127_4378781_0	234267.Acid_1490	7.013e-158	520.0	COG3276@1|root,COG3276@2|Bacteria,3Y6R2@57723|Acidobacteria	57723|Acidobacteria	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SYD2_k127_4378781_12	926569.ANT_16540	6.524e-10	66.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SYD2_k127_4378781_7	991.IW20_07120	7.328e-37	144.0	2AFHA@1|root,315HT@2|Bacteria,4NQ5F@976|Bacteroidetes,1I2SM@117743|Flavobacteriia,2NW8F@237|Flavobacterium	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SYD2_k127_4393844_5	204669.Acid345_3633	1.275e-78	277.0	COG0770@1|root,COG0770@2|Bacteria,3Y3I2@57723|Acidobacteria,2JHW4@204432|Acidobacteriia	204432|Acidobacteriia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SYD2_k127_4393844_2	335283.Neut_0249	6.282e-107	358.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,372PV@32003|Nitrosomonadales	28216|Betaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SYD2_k127_4393844_1	1382359.JIAL01000001_gene1975	3.994e-119	399.0	COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria,2JHQF@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SYD2_k127_4393844_4	204669.Acid345_3630	2.757e-92	317.0	COG0772@1|root,COG0772@2|Bacteria,3Y330@57723|Acidobacteria,2JHW0@204432|Acidobacteriia	204432|Acidobacteriia	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SYD2_k127_4393844_3	404589.Anae109_3884	3.587e-99	335.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2YWEZ@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SYD2_k127_4393844_0	338966.Ppro_3288	2.415e-131	428.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,43U76@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SYD2_k127_4397018_0	1297581.H919_13400	3.618e-133	449.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,21W9Q@150247|Anoxybacillus	91061|Bacilli	S	ABC transporter	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SYD2_k127_4397018_4	639282.DEFDS_1151	2.44e-19	100.0	COG0760@1|root,COG0760@2|Bacteria,2GFF3@200930|Deferribacteres	200930|Deferribacteres	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
SYD2_k127_4397018_3	1379281.AVAG01000065_gene1170	7.516e-22	96.0	COG0227@1|root,COG0227@2|Bacteria,1PTFN@1224|Proteobacteria,42V1S@68525|delta/epsilon subdivisions,2WR85@28221|Deltaproteobacteria,2MD8Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SYD2_k127_4397018_2	264732.Moth_1495	1.822e-47	173.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,42GJ3@68295|Thermoanaerobacterales	186801|Clostridia	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SYD2_k127_4397018_1	1382359.JIAL01000001_gene3036	2.128e-65	235.0	COG0308@1|root,COG0308@2|Bacteria,3Y3ZS@57723|Acidobacteria,2JK79@204432|Acidobacteriia	204432|Acidobacteriia	E	Phospholipase B	-	-	-	-	-	-	-	-	-	-	-	-	Phospholip_B
SYD2_k127_4424974_4	857293.CAAU_2283	6.257e-31	123.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,36EFC@31979|Clostridiaceae	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SYD2_k127_4424974_3	234267.Acid_7287	2.282e-42	164.0	COG0461@1|root,COG0461@2|Bacteria,3Y6JQ@57723|Acidobacteria	57723|Acidobacteria	F	Phosphoribosyl transferase domain	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SYD2_k127_4424974_6	1229780.BN381_330122	8.304e-19	92.0	COG1051@1|root,COG1051@2|Bacteria,2ISCR@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SYD2_k127_4424974_0	204669.Acid345_2431	4.097e-88	302.0	COG2605@1|root,COG2605@2|Bacteria,3Y56A@57723|Acidobacteria,2JP24@204432|Acidobacteriia	204432|Acidobacteriia	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SYD2_k127_4424974_7	1040986.ATYO01000005_gene6371	1.14e-10	71.0	COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,2UEND@28211|Alphaproteobacteria,43KD4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SYD2_k127_4424974_5	247490.KSU1_D0145	3.867e-21	100.0	COG0589@1|root,COG0589@2|Bacteria,2J0XB@203682|Planctomycetes	203682|Planctomycetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SYD2_k127_4424974_1	42256.RradSPS_3047	2.946e-48	184.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4CPVZ@84995|Rubrobacteria	84995|Rubrobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SYD2_k127_4424974_2	234267.Acid_5050	2.855e-45	179.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Big_2,F5_F8_type_C,Glyco_hydro_98C,Glyco_hydro_98M,NPCBM,Peptidase_M16,Peptidase_M16_C
SYD2_k127_4424974_8	671143.DAMO_0870	1.376e-08	67.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	ko:K03194	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	CHAP,SLT
SYD2_k127_4424974_9	1379858.N508_02108	5.909e-07	54.0	COG1044@1|root,COG1044@2|Bacteria,2GF9J@200930|Deferribacteres	200930|Deferribacteres	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
SYD2_k127_4475436_3	1396141.BATP01000056_gene3279	2.81e-106	359.0	COG3146@1|root,COG3146@2|Bacteria	2|Bacteria	S	Peptidogalycan biosysnthesis/recognition	bioF2	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Acetyltransf_6,FemAB_like
SYD2_k127_4475436_2	1537715.JQFJ01000001_gene2734	3.065e-146	479.0	COG4805@1|root,COG4805@2|Bacteria,1NRZP@1224|Proteobacteria,2UNXX@28211|Alphaproteobacteria,2K9QH@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SYD2_k127_4475436_1	1382359.JIAL01000001_gene2460	7.553e-169	542.0	COG1680@1|root,COG1680@2|Bacteria,3Y3DY@57723|Acidobacteria,2JHVC@204432|Acidobacteriia	204432|Acidobacteriia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SYD2_k127_4475436_0	1131553.JIBI01000031_gene2248	4.63e-234	738.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2VKEE@28216|Betaproteobacteria,372CG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14
SYD2_k127_4475436_4	1379270.AUXF01000005_gene598	4.472e-56	199.0	COG0334@1|root,COG0334@2|Bacteria,1ZTBQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SYD2_k127_4503399_0	1267533.KB906735_gene5103	1.55e-144	466.0	COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria,2JHZ6@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SYD2_k127_4503399_1	639282.DEFDS_1746	1.167e-72	250.0	COG0522@1|root,COG0522@2|Bacteria,2GF55@200930|Deferribacteres	200930|Deferribacteres	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SYD2_k127_4503399_3	1267535.KB906767_gene2680	2.641e-47	173.0	COG0100@1|root,COG0100@2|Bacteria,3Y4BS@57723|Acidobacteria,2JJ4Q@204432|Acidobacteriia	204432|Acidobacteriia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SYD2_k127_4503399_2	234267.Acid_5093	4.113e-49	177.0	COG0099@1|root,COG0099@2|Bacteria,3Y4KC@57723|Acidobacteria	57723|Acidobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SYD2_k127_4503399_5	234267.Acid_5094	3.05e-15	75.0	COG0257@1|root,COG0257@2|Bacteria,3Y5X6@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SYD2_k127_4503399_4	401053.AciPR4_3213	2.594e-32	126.0	COG0361@1|root,COG0361@2|Bacteria,3Y55Z@57723|Acidobacteria,2JJUQ@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SYD2_k127_4507028_5	1144275.COCOR_04873	6.897e-46	173.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales	28221|Deltaproteobacteria	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT_2,Pro_isomerase
SYD2_k127_4507028_4	1128421.JAGA01000004_gene2493	1.427e-46	191.0	COG0308@1|root,COG0308@2|Bacteria,2NPPZ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M1 domain	pepN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SYD2_k127_4507028_7	1198114.AciX9_0478	4.595e-20	97.0	2DMJE@1|root,32RYR@2|Bacteria,3Y4XN@57723|Acidobacteria,2JJFS@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4112)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4112
SYD2_k127_4507028_10	1117108.PAALTS15_21843	6.183e-07	58.0	COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli,26ZTC@186822|Paenibacillaceae	91061|Bacilli	S	general stress protein	ytxH	-	-	-	-	-	-	-	-	-	-	-	YtxH
SYD2_k127_4507028_0	204669.Acid345_1861	0.0	1033.0	COG0060@1|root,COG0060@2|Bacteria,3Y3JW@57723|Acidobacteria,2JIQ2@204432|Acidobacteriia	204432|Acidobacteriia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
SYD2_k127_4507028_6	1042377.AFPJ01000029_gene546	3.729e-30	126.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,467DX@72275|Alteromonadaceae	1236|Gammaproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SYD2_k127_4507028_3	204669.Acid345_2869	1.459e-63	227.0	COG0682@1|root,COG0682@2|Bacteria,3Y4HT@57723|Acidobacteria,2JJTI@204432|Acidobacteriia	204432|Acidobacteriia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SYD2_k127_4507028_1	234267.Acid_2600	2.02e-107	357.0	COG2404@1|root,COG2404@2|Bacteria,3Y98M@57723|Acidobacteria	57723|Acidobacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4507028_9	1242864.D187_000299	2.713e-07	57.0	2DQCB@1|root,335WZ@2|Bacteria,1N06Y@1224|Proteobacteria	1224|Proteobacteria	S	Family of unknown function (DUF5335)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5335
SYD2_k127_4507028_2	204669.Acid345_4418	9.392e-79	272.0	2CHAC@1|root,2Z7QK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4507028_8	251229.Chro_2976	2.741e-18	86.0	COG0365@1|root,COG0365@2|Bacteria,1G0E7@1117|Cyanobacteria,3VIYI@52604|Pleurocapsales	1117|Cyanobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SYD2_k127_450823_2	945713.IALB_0646	7.931e-82	277.0	COG0176@1|root,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135	2.2.1.2,5.3.1.9	ko:K00616,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SYD2_k127_450823_7	1123377.AUIV01000002_gene1158	5.855e-35	151.0	2AQ2A@1|root,31F7E@2|Bacteria,1QCMG@1224|Proteobacteria,1T8CS@1236|Gammaproteobacteria,1XAFU@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_450823_8	204669.Acid345_0196	8.58e-23	111.0	COG4733@1|root,COG4733@2|Bacteria,3Y53H@57723|Acidobacteria,2JJMD@204432|Acidobacteriia	204432|Acidobacteriia	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_450823_5	204669.Acid345_0212	4.183e-66	228.0	COG1220@1|root,COG1220@2|Bacteria,3Y2K2@57723|Acidobacteria,2JIS7@204432|Acidobacteriia	204432|Acidobacteriia	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
SYD2_k127_450823_0	240015.ACP_2657	2.997e-135	437.0	COG1220@1|root,COG1220@2|Bacteria,3Y2K2@57723|Acidobacteria,2JIS7@204432|Acidobacteriia	204432|Acidobacteriia	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
SYD2_k127_450823_3	1382359.JIAL01000001_gene1358	1.097e-73	252.0	COG5405@1|root,COG5405@2|Bacteria,3Y42U@57723|Acidobacteria,2JIR7@204432|Acidobacteriia	204432|Acidobacteriia	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
SYD2_k127_450823_6	1219084.AP014508_gene467	1.316e-48	183.0	COG2071@1|root,COG2071@2|Bacteria	2|Bacteria	S	gamma-glutamyl-gamma-aminobutyrate hydrolase activity	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SYD2_k127_450823_4	1191523.MROS_1806	4.283e-72	251.0	COG1028@1|root,COG1028@2|Bacteria	1191523.MROS_1806|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
SYD2_k127_450823_1	439235.Dalk_0937	1.313e-117	388.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria,2MI37@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
SYD2_k127_4515415_3	234267.Acid_6464	1.095e-45	173.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_6464|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4515415_2	1122182.KB903834_gene5898	2.702e-87	297.0	COG2013@1|root,COG2013@2|Bacteria,2I9XC@201174|Actinobacteria,4DJFC@85008|Micromonosporales	201174|Actinobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
SYD2_k127_4515415_1	357808.RoseRS_4055	5.835e-133	434.0	COG0505@1|root,COG0505@2|Bacteria,2G5S1@200795|Chloroflexi,3755X@32061|Chloroflexia	32061|Chloroflexia	F	TIGRFAM carbamoyl-phosphate synthase, small subunit	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SYD2_k127_4515415_6	330214.NIDE1693	2.563e-22	98.0	COG4185@1|root,COG4185@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
SYD2_k127_4515415_5	118005.AWNK01000010_gene385	1.486e-26	114.0	COG4185@1|root,COG4185@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Zeta_toxin
SYD2_k127_4515415_4	204669.Acid345_0566	2.516e-40	165.0	COG0628@1|root,COG0628@2|Bacteria,3Y40R@57723|Acidobacteria,2JIX8@204432|Acidobacteriia	204432|Acidobacteriia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SYD2_k127_4515415_0	886293.Sinac_2348	5.949e-157	499.0	COG0365@1|root,COG0365@2|Bacteria,2IX5P@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SYD2_k127_4519385_6	1133849.O3I_002145	4.486e-09	61.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4FW91@85025|Nocardiaceae	201174|Actinobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	GO:0008150,GO:0040007	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS
SYD2_k127_4519385_0	1267533.KB906733_gene3053	5.449e-254	799.0	COG0465@1|root,COG0465@2|Bacteria,3Y2UK@57723|Acidobacteria,2JI9D@204432|Acidobacteriia	204432|Acidobacteriia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SYD2_k127_4519385_1	234267.Acid_1867	2.15e-161	520.0	COG0665@1|root,COG0665@2|Bacteria,3Y5BS@57723|Acidobacteria	57723|Acidobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303,ko:K21061	ko00260,ko00330,ko01100,map00260,map00330,map01100	-	R00610,R11428	RC00060,RC00135,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SYD2_k127_4519385_4	234267.Acid_6501	5.214e-78	271.0	COG2897@1|root,COG2897@2|Bacteria,3Y7T0@57723|Acidobacteria	57723|Acidobacteria	M	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SYD2_k127_4519385_2	671143.DAMO_0892	3.518e-123	403.0	COG4870@1|root,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	3.4.22.38	ko:K01371	ko04142,ko04210,ko04380,ko04620,ko05323,map04142,map04210,map04380,map04620,map05323	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_C1
SYD2_k127_4519385_3	760192.Halhy_4135	8.527e-79	271.0	COG4947@1|root,COG4947@2|Bacteria,4NJWM@976|Bacteroidetes,1IVCZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SYD2_k127_4519385_5	1229172.JQFA01000004_gene1228	2.71e-37	143.0	2CCSR@1|root,32RWC@2|Bacteria,1GA04@1117|Cyanobacteria,1HDA0@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SYD2_k127_4538703_2	1121403.AUCV01000008_gene1607	5.384e-09	58.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MI1N@213118|Desulfobacterales	28221|Deltaproteobacteria	T	sigma-54 factor interaction domain-containing protein	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
SYD2_k127_4538703_0	330214.NIDE0778	4.223e-81	290.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
SYD2_k127_454321_1	1249997.JHZW01000002_gene589	8.667e-35	137.0	2AFHA@1|root,315HT@2|Bacteria,4NQ5F@976|Bacteroidetes,1I2SM@117743|Flavobacteriia,2PIMZ@252356|Maribacter	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SYD2_k127_454321_0	1267535.KB906767_gene4255	2.123e-75	260.0	COG0353@1|root,COG0353@2|Bacteria,3Y31E@57723|Acidobacteria,2JHQM@204432|Acidobacteriia	204432|Acidobacteriia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SYD2_k127_454321_4	1047013.AQSP01000101_gene612	1.256e-23	104.0	COG0718@1|root,COG0718@2|Bacteria,2NPUK@2323|unclassified Bacteria	2|Bacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363	-	ko:K06187,ko:K09747	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	YbaB_DNA_bd
SYD2_k127_454321_3	649638.Trad_1357	2.232e-26	123.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	PE-PPE,VKG_Carbox
SYD2_k127_454321_2	1406840.Q763_00270	3.975e-34	135.0	COG3738@1|root,COG3738@2|Bacteria,4NM46@976|Bacteroidetes,1I2QD@117743|Flavobacteriia,2NUWS@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF1287)	-	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
SYD2_k127_4567094_2	485913.Krac_2947	3.754e-121	396.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SYD2_k127_4567094_11	671143.DAMO_2984	1.628e-05	57.0	2BHGH@1|root,32BIN@2|Bacteria,2NRSQ@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
SYD2_k127_4567094_10	317936.Nos7107_1718	4.516e-12	73.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SYD2_k127_4567094_7	317936.Nos7107_1719	1.128e-51	192.0	2ERTE@1|root,33JCN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4567094_6	1123508.JH636449_gene7410	1.676e-53	207.0	COG5373@1|root,COG5373@2|Bacteria	2|Bacteria	KLT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999,LptC,NLPC_P60,SH3_3
SYD2_k127_4567094_4	1123508.JH636449_gene7409	5.131e-63	241.0	COG5373@1|root,COG5373@2|Bacteria,2J4TM@203682|Planctomycetes	203682|Planctomycetes	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
SYD2_k127_4567094_3	246197.MXAN_6492	1.035e-104	353.0	COG0673@1|root,COG0673@2|Bacteria,1N0VK@1224|Proteobacteria,43C12@68525|delta/epsilon subdivisions,2WXMX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SYD2_k127_4567094_1	204669.Acid345_2039	2.894e-186	604.0	COG0145@1|root,COG0145@2|Bacteria,3Y6D5@57723|Acidobacteria,2JKXC@204432|Acidobacteriia	204432|Acidobacteriia	EQ	Hydantoinase/oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SYD2_k127_4567094_0	204669.Acid345_3921	3.277e-192	614.0	COG0146@1|root,COG0146@2|Bacteria,3Y6W2@57723|Acidobacteria,2JKCE@204432|Acidobacteriia	204432|Acidobacteriia	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SYD2_k127_4567094_5	1278073.MYSTI_05558	1.424e-61	220.0	COG1435@1|root,COG1435@2|Bacteria,1PY2K@1224|Proteobacteria,42RJI@68525|delta/epsilon subdivisions,2WNKR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
SYD2_k127_45878_1	1267535.KB906767_gene2327	2.959e-47	175.0	COG0500@1|root,COG2226@2|Bacteria,3Y752@57723|Acidobacteria	57723|Acidobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_45878_0	635013.TherJR_1583	5.818e-94	324.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,260YG@186807|Peptococcaceae	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512,PDZ
SYD2_k127_459483_1	321327.CYA_0206	1.83e-129	429.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1G1DF@1117|Cyanobacteria,1GZBH@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SYD2_k127_459483_7	251221.35210651	1.956e-46	173.0	COG1670@1|root,COG1670@2|Bacteria,1G7I7@1117|Cyanobacteria	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SYD2_k127_459483_3	1123256.KB907928_gene2063	2.423e-76	266.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1X3EP@135614|Xanthomonadales	135614|Xanthomonadales	L	Tyrosine recombinase xerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SYD2_k127_459483_4	1185876.BN8_03503	2.397e-69	238.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,47PQK@768503|Cytophagia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SYD2_k127_459483_6	251229.Chro_0773	4.278e-58	206.0	COG0454@1|root,COG0456@2|Bacteria,1GQNY@1117|Cyanobacteria	1117|Cyanobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SYD2_k127_459483_11	1278073.MYSTI_04560	0.0006472	48.0	COG0457@1|root,COG0457@2|Bacteria,1NFC8@1224|Proteobacteria,42VYT@68525|delta/epsilon subdivisions,2WRFT@28221|Deltaproteobacteria,2Z1XW@29|Myxococcales	28221|Deltaproteobacteria	S	adventurous gliding protein T	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_10,TPR_16,TPR_19,TPR_2,TPR_8
SYD2_k127_459483_8	1382359.JIAL01000001_gene3030	2.74e-27	117.0	COG0239@1|root,COG0239@2|Bacteria,3Y54A@57723|Acidobacteria,2JJPV@204432|Acidobacteriia	204432|Acidobacteriia	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SYD2_k127_459483_10	941449.dsx2_1987	0.0005125	48.0	COG0517@1|root,COG1993@1|root,COG3448@1|root,COG0517@2|Bacteria,COG1993@2|Bacteria,COG3448@2|Bacteria,1N0EM@1224|Proteobacteria,42TZK@68525|delta/epsilon subdivisions,2WQ2E@28221|Deltaproteobacteria,2M86Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	CBS,DUF190
SYD2_k127_459483_5	1382359.JIAL01000001_gene3031	1.231e-60	218.0	COG1993@1|root,COG1993@2|Bacteria,3Y605@57723|Acidobacteria,2JM1G@204432|Acidobacteriia	204432|Acidobacteriia	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
SYD2_k127_459483_2	643648.Slip_0474	5.279e-81	291.0	COG0699@1|root,COG0699@2|Bacteria,1TR0Q@1239|Firmicutes,24BWJ@186801|Clostridia	186801|Clostridia	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SYD2_k127_459483_0	1267535.KB906767_gene758	6.102e-136	441.0	COG1530@1|root,COG1530@2|Bacteria,3Y40K@57723|Acidobacteria,2JHQU@204432|Acidobacteriia	204432|Acidobacteriia	J	PFAM RNA-binding protein AU-1 Ribonuclease E G	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
SYD2_k127_4597908_0	1267535.KB906767_gene4853	0.0	1110.0	COG1274@1|root,COG1274@2|Bacteria,3Y2IH@57723|Acidobacteria,2JIZH@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SYD2_k127_4597908_7	1184267.A11Q_79	7.467e-49	182.0	2AY4N@1|root,31Q6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4597908_1	1300345.LF41_1080	3.958e-155	506.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria,1XA6G@135614|Xanthomonadales	135614|Xanthomonadales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4597908_3	639030.JHVA01000001_gene2812	4.254e-104	344.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
SYD2_k127_4597908_10	1192034.CAP_8329	1.544e-06	58.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2YWPS@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SYD2_k127_4597908_2	1384056.N787_06630	6.609e-133	435.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,1QYHB@1224|Proteobacteria,1T613@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SYD2_k127_4597908_5	945713.IALB_1247	7.892e-71	249.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SYD2_k127_4597908_9	1340493.JNIF01000004_gene771	1.004e-27	126.0	COG0633@1|root,COG0633@2|Bacteria	2|Bacteria	C	Ferredoxin	-	GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858	1.18.1.3	ko:K00529,ko:K04755,ko:K08952,ko:K08953,ko:K08954,ko:K15765	ko00071,ko00360,ko00623,ko00920,ko01100,ko01120,ko01220,map00071,map00360,map00623,map00920,map01100,map01120,map01220	M00538,M00545	R02000,R02550,R03562,R05666,R06782,R06783,R09513	RC00098,RC00269,RC00490,RC02556	br01602,ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	FAD_binding_6,Fer2
SYD2_k127_4597908_8	314230.DSM3645_14245	2.147e-28	116.0	2BZBR@1|root,32YH6@2|Bacteria,2J41E@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4597908_6	204669.Acid345_1150	8.92e-58	209.0	arCOG09454@1|root,31B41@2|Bacteria,3Y8HD@57723|Acidobacteria,2JNG1@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4597908_4	525904.Tter_1596	2.464e-83	282.0	COG3880@1|root,COG3880@2|Bacteria,2NPCX@2323|unclassified Bacteria	2|Bacteria	S	Cytochrome c7 and related cytochrome c	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,GSu_C4xC__C2xCH,UVR
SYD2_k127_4605924_2	1173025.GEI7407_0828	3.141e-19	91.0	COG0058@1|root,COG0058@2|Bacteria,1G1HB@1117|Cyanobacteria,1HA6X@1150|Oscillatoriales	1117|Cyanobacteria	G	Protein of unknown function (DUF3417)	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SYD2_k127_4605924_0	159087.Daro_1928	3.908e-63	223.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2VRGS@28216|Betaproteobacteria,2KWIF@206389|Rhodocyclales	206389|Rhodocyclales	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SYD2_k127_4605924_1	639030.JHVA01000001_gene673	1.845e-24	112.0	2A9J8@1|root,30YRM@2|Bacteria,3Y4IZ@57723|Acidobacteria,2JJDB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_462547_2	1382305.AZUC01000047_gene908	6.051e-16	79.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,4HAV5@91061|Bacilli,26CUT@186818|Planococcaceae	91061|Bacilli	S	YmdB-like protein	ymdB	GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578	-	ko:K02029,ko:K02030,ko:K09769	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	YmdB
SYD2_k127_462547_1	1267533.KB906733_gene3589	8.499e-38	148.0	COG0824@1|root,COG0824@2|Bacteria,3Y4WZ@57723|Acidobacteria,2JJIE@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SYD2_k127_462547_0	525904.Tter_1099	1.306e-60	226.0	COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_462547_3	379066.GAU_1707	1.709e-11	69.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SYD2_k127_4628992_1	204669.Acid345_0509	5.431e-48	175.0	COG0745@1|root,COG0745@2|Bacteria,3Y4R4@57723|Acidobacteria,2JJBD@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator, receiver	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SYD2_k127_4628992_0	682795.AciX8_3966	7.74e-95	327.0	COG0642@1|root,COG2205@2|Bacteria,3Y2W3@57723|Acidobacteria,2JIDP@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
SYD2_k127_4628992_2	1183438.GKIL_1468	1.245e-11	66.0	COG2124@1|root,COG2124@2|Bacteria,1G57F@1117|Cyanobacteria	1117|Cyanobacteria	Q	Cytochrome p450	-	-	-	ko:K15468	-	-	-	-	ko00000,ko01008	-	-	-	p450
SYD2_k127_466121_0	1341151.ASZU01000010_gene1916	8.136e-81	276.0	COG3253@1|root,COG3253@2|Bacteria,1VZPB@1239|Firmicutes,4HZ7E@91061|Bacilli,27B36@186824|Thermoactinomycetaceae	91061|Bacilli	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SYD2_k127_466121_2	401053.AciPR4_1215	9.917e-30	123.0	COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria	57723|Acidobacteria	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
SYD2_k127_466121_1	401053.AciPR4_1216	5.131e-48	188.0	COG1290@1|root,COG1290@2|Bacteria,3Y4F0@57723|Acidobacteria,2JKSY@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C
SYD2_k127_466121_4	1536774.H70357_00500	0.0005251	48.0	COG2010@1|root,COG2010@2|Bacteria,1VEEP@1239|Firmicutes,4HP6N@91061|Bacilli,26YFW@186822|Paenibacillaceae	91061|Bacilli	C	Cytochrome C oxidase, cbb3-type, subunit III	cccB	-	-	ko:K12263,ko:K13300	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
SYD2_k127_466121_3	56780.SYN_03595	7.719e-05	51.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,42PXQ@68525|delta/epsilon subdivisions,2WKHU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SYD2_k127_4692117_3	1121924.ATWH01000019_gene2928	3.104e-35	147.0	COG0715@1|root,COG0715@2|Bacteria,2IDBN@201174|Actinobacteria	201174|Actinobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SYD2_k127_4692117_1	351607.Acel_0886	8.417e-64	228.0	COG0600@1|root,COG0600@2|Bacteria,2GP2J@201174|Actinobacteria,4EW2R@85013|Frankiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SYD2_k127_4692117_2	351607.Acel_0887	1.901e-55	203.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4EVVP@85013|Frankiales	201174|Actinobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SYD2_k127_4692117_0	1120983.KB894571_gene2468	2.427e-125	410.0	COG1073@1|root,COG1073@2|Bacteria,1PJHR@1224|Proteobacteria,2U2QB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4692117_4	1380347.JNII01000009_gene2009	1.278e-28	116.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SYD2_k127_4759040_6	583345.Mmol_0651	5.667e-09	58.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2VINM@28216|Betaproteobacteria,2KKCN@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
SYD2_k127_4759040_5	316278.SynRCC307_2224	2.727e-09	68.0	COG0526@1|root,COG0526@2|Bacteria,1G5X2@1117|Cyanobacteria,1H0U8@1129|Synechococcus	1117|Cyanobacteria	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	txlA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	-	-	-	-	-	-	-	-	iAPECO1_1312.trxA	Thioredoxin
SYD2_k127_4759040_3	1054213.HMPREF9946_03165	3.917e-22	108.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria	1224|Proteobacteria	L	nuclease	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	Excalibur,SNase
SYD2_k127_4759040_1	316274.Haur_4830	1.273e-108	367.0	COG2308@1|root,COG2308@2|Bacteria,2G7ZB@200795|Chloroflexi,3754D@32061|Chloroflexia	32061|Chloroflexia	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SYD2_k127_4759040_2	448385.sce0162	3.678e-53	194.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42TDG@68525|delta/epsilon subdivisions,2WPJP@28221|Deltaproteobacteria,2Z1CP@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SYD2_k127_4759040_0	1183438.GKIL_2649	1.101e-108	370.0	COG3503@1|root,COG3503@2|Bacteria	2|Bacteria	J	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF418
SYD2_k127_4759040_4	608538.HTH_1866	2.025e-19	90.0	COG0111@1|root,COG0111@2|Bacteria,2G3T5@200783|Aquificae	200783|Aquificae	E	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SYD2_k127_4776529_11	204669.Acid345_2187	1.382e-07	55.0	COG4948@1|root,COG4948@2|Bacteria,3Y2QQ@57723|Acidobacteria,2JITG@204432|Acidobacteriia	204432|Acidobacteriia	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SYD2_k127_4776529_5	639030.JHVA01000001_gene2607	1.664e-85	297.0	COG0624@1|root,COG0624@2|Bacteria,3Y3J0@57723|Acidobacteria,2JI3Y@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SYD2_k127_4776529_8	234267.Acid_1304	3.394e-57	228.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y3SU@57723|Acidobacteria	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SYD2_k127_4776529_0	1047013.AQSP01000108_gene2065	0.0	1254.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SYD2_k127_4776529_10	1117108.PAALTS15_04833	7.335e-38	157.0	COG1680@1|root,COG1680@2|Bacteria,1UT07@1239|Firmicutes,4HMEY@91061|Bacilli,26QSV@186822|Paenibacillaceae	91061|Bacilli	V	Domain of unknown function (DUF3471)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SYD2_k127_4776529_3	886377.Murru_3303	3.817e-212	673.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1HYSX@117743|Flavobacteriia	976|Bacteroidetes	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SYD2_k127_4776529_2	861299.J421_6087	1.966e-259	812.0	COG2936@1|root,COG2936@2|Bacteria,1ZTD6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SYD2_k127_4776529_4	1163407.UU7_05648	6.021e-168	551.0	COG1680@1|root,COG1680@2|Bacteria,1PQ2Z@1224|Proteobacteria,1SYR1@1236|Gammaproteobacteria,1XCSI@135614|Xanthomonadales	135614|Xanthomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SYD2_k127_4776529_1	1198114.AciX9_1369	4.946e-292	910.0	COG5276@1|root,COG5276@2|Bacteria,3Y393@57723|Acidobacteria,2JMHD@204432|Acidobacteriia	2|Bacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SYD2_k127_4776529_6	1198114.AciX9_1370	1.939e-70	246.0	COG3544@1|root,COG3544@2|Bacteria,3Y4G7@57723|Acidobacteria,2JKAH@204432|Acidobacteriia	2|Bacteria	P	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
SYD2_k127_4776529_7	420662.Mpe_A2300	4.858e-66	230.0	COG0346@1|root,COG0346@2|Bacteria,1RK3P@1224|Proteobacteria,2W3DN@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SYD2_k127_4776529_9	1379698.RBG1_1C00001G0607	5.391e-45	177.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
SYD2_k127_4780297_1	926561.KB900623_gene1122	2.262e-86	299.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,3WAFN@53433|Halanaerobiales	186801|Clostridia	U	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SYD2_k127_4780297_2	1121033.AUCF01000018_gene5855	4.321e-86	295.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,2TSTD@28211|Alphaproteobacteria,2JPWK@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SYD2_k127_4780297_0	1430331.EP10_18360	3.517e-96	322.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1WE42@129337|Geobacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SYD2_k127_4780297_3	1521187.JPIM01000044_gene3289	1.764e-74	257.0	COG0572@1|root,COG0572@2|Bacteria,2G6D5@200795|Chloroflexi,376PV@32061|Chloroflexia	32061|Chloroflexia	F	PFAM phosphoribulokinase uridine kinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
SYD2_k127_4820869_0	469371.Tbis_2861	7.683e-212	671.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4E0S6@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SYD2_k127_4820869_1	1121468.AUBR01000021_gene2825	8.292e-114	381.0	COG1449@1|root,COG1449@2|Bacteria,1UVAN@1239|Firmicutes,24B0Y@186801|Clostridia,42HS1@68295|Thermoanaerobacterales	186801|Clostridia	G	Domain of unknown function (DUF3536)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
SYD2_k127_4826427_0	404589.Anae109_3354	5.596e-99	344.0	COG4585@1|root,COG4585@2|Bacteria,1RBN9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SYD2_k127_4826427_1	404589.Anae109_3355	5.99e-48	180.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria	1224|Proteobacteria	K	response regulator	-	-	-	ko:K07685	ko02020,map02020	M00472	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SYD2_k127_4826427_2	290397.Adeh_2125	5.042e-09	64.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria	1224|Proteobacteria	V	Kelch	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4
SYD2_k127_4833877_2	1502850.FG91_03420	1.082e-47	190.0	COG3193@1|root,COG3193@2|Bacteria,1R3RC@1224|Proteobacteria,2U39K@28211|Alphaproteobacteria,2K2UI@204457|Sphingomonadales	204457|Sphingomonadales	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
SYD2_k127_4833877_1	1210884.HG799465_gene11817	8.536e-161	531.0	COG3827@1|root,COG3827@2|Bacteria,2IXVY@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4833877_0	234267.Acid_4317	0.0	1275.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	LVIVD,SBP56
SYD2_k127_4833877_3	234267.Acid_7266	8.522e-17	92.0	COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3
SYD2_k127_4833877_5	653045.Strvi_1637	2.754e-06	57.0	COG0477@1|root,COG4932@1|root,COG2814@2|Bacteria,COG4932@2|Bacteria,2H8UD@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1,Sugar_tr
SYD2_k127_4849052_8	313606.M23134_01927	5.942e-23	115.0	COG3292@1|root,COG4990@1|root,COG3292@2|Bacteria,COG4990@2|Bacteria	2|Bacteria	-	-	-	GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	CHAP,G8,PG_binding_1,Peptidase_S46
SYD2_k127_4849052_9	682795.AciX8_0676	2.677e-20	107.0	COG3209@1|root,COG3209@2|Bacteria,3Y7FC@57723|Acidobacteria,2JKK9@204432|Acidobacteriia	204432|Acidobacteriia	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
SYD2_k127_4849052_6	247490.KSU1_C0427	2.316e-40	161.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SYD2_k127_4849052_4	374847.Kcr_0645	1.508e-52	200.0	COG1131@1|root,arCOG00194@2157|Archaea	2157|Archaea	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SYD2_k127_4849052_1	1267533.KB906737_gene1961	1.311e-96	323.0	COG1173@1|root,COG1173@2|Bacteria,3Y45P@57723|Acidobacteria,2JIKH@204432|Acidobacteriia	204432|Acidobacteriia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SYD2_k127_4849052_2	1267533.KB906737_gene1964	4.216e-94	320.0	COG0601@1|root,COG0601@2|Bacteria,3Y437@57723|Acidobacteria,2JHY6@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SYD2_k127_4849052_3	243090.RB2752	9.355e-61	219.0	COG0500@1|root,COG2226@2|Bacteria,2IYWE@203682|Planctomycetes	203682|Planctomycetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SYD2_k127_4849052_10	378806.STAUR_4212	1.91e-09	70.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2WPVT@28221|Deltaproteobacteria,2YV10@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SYD2_k127_4849052_7	234267.Acid_4425	4.896e-27	123.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SYD2_k127_4849052_11	240015.ACP_3477	1.972e-09	70.0	COG0810@1|root,COG0810@2|Bacteria,3Y58J@57723|Acidobacteria,2JJPH@204432|Acidobacteriia	204432|Acidobacteriia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
SYD2_k127_4849052_5	639030.JHVA01000001_gene1782	3.727e-47	175.0	COG2318@1|root,COG2318@2|Bacteria,3Y5FN@57723|Acidobacteria,2JJTU@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SYD2_k127_4849052_0	661478.OP10G_4632	4.712e-184	602.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SYD2_k127_4849514_6	1121904.ARBP01000012_gene1388	8.651e-28	123.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,47PHD@768503|Cytophagia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SYD2_k127_4849514_2	861299.J421_2666	4.74e-126	417.0	COG0508@1|root,COG0508@2|Bacteria,1ZSYJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SYD2_k127_4849514_1	1411123.JQNH01000001_gene1359	1.511e-134	435.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,Transket_pyr,Transketolase_C
SYD2_k127_4849514_3	671143.DAMO_1598	4.393e-123	405.0	COG1071@1|root,COG1071@2|Bacteria,2NQC2@2323|unclassified Bacteria	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SYD2_k127_4849514_4	1198114.AciX9_2892	3.279e-116	406.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,3Y9F7@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
SYD2_k127_4849514_0	485913.Krac_11972	8.615e-244	770.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SYD2_k127_4849514_5	204669.Acid345_4530	5.376e-103	358.0	COG4805@1|root,COG4805@2|Bacteria,3Y4PP@57723|Acidobacteria,2JKV8@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4850643_0	63737.Npun_R0239	2.652e-124	409.0	COG2520@1|root,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
SYD2_k127_49212_0	479434.Sthe_0801	3.193e-107	357.0	COG0476@1|root,COG0476@2|Bacteria,2G5Q1@200795|Chloroflexi,27XM2@189775|Thermomicrobia	189775|Thermomicrobia	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
SYD2_k127_49212_1	237368.SCABRO_03813	1.401e-97	337.0	COG0169@1|root,COG0710@1|root,COG0169@2|Bacteria,COG0710@2|Bacteria,2IXKU@203682|Planctomycetes	203682|Planctomycetes	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroD	-	1.1.1.25,4.2.1.10	ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
SYD2_k127_49212_2	272558.10172725	3.178e-65	234.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,1ZAXC@1386|Bacillus	91061|Bacilli	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SYD2_k127_49212_3	195253.Syn6312_0268	5.314e-36	139.0	COG1432@1|root,COG1432@2|Bacteria,1G01P@1117|Cyanobacteria,1GYTQ@1129|Synechococcus	1117|Cyanobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
SYD2_k127_4940439_2	1158338.JNLJ01000001_gene566	3.362e-25	112.0	COG1267@1|root,COG1267@2|Bacteria,2G497@200783|Aquificae	200783|Aquificae	I	PFAM Phosphatidylglycerophosphatase A	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
SYD2_k127_4940439_1	926550.CLDAP_21370	7.834e-68	243.0	COG0598@1|root,COG0598@2|Bacteria,2G6EQ@200795|Chloroflexi	200795|Chloroflexi	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SYD2_k127_4940439_0	667014.Thein_0855	1.916e-134	444.0	COG0111@1|root,COG2150@1|root,COG0111@2|Bacteria,COG2150@2|Bacteria,2GH7H@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SYD2_k127_4995027_7	234267.Acid_5454	1.5e-45	175.0	COG0511@1|root,COG1413@1|root,COG0511@2|Bacteria,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	pcmV	-	2.3.1.12	ko:K00627,ko:K02160,ko:K07402	ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00307,M00376	R00209,R00742,R02569	RC00004,RC00040,RC00367,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,MDMPI_C,MDMPI_N,XdhC_C,XdhC_CoxI
SYD2_k127_4995027_10	1027292.HMPREF9372_3247	1.114e-21	102.0	COG2020@1|root,COG2020@2|Bacteria,1V3IZ@1239|Firmicutes,4HSCI@91061|Bacilli	91061|Bacilli	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SYD2_k127_4995027_9	204669.Acid345_2222	1.048e-36	143.0	COG2322@1|root,COG2322@2|Bacteria,3Y4U9@57723|Acidobacteria,2JJKU@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
SYD2_k127_4995027_4	234267.Acid_5592	4.459e-65	228.0	COG1845@1|root,COG1845@2|Bacteria,3Y5GJ@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SYD2_k127_4995027_8	1267535.KB906767_gene3690	2.63e-38	152.0	COG1845@1|root,COG1845@2|Bacteria	2|Bacteria	C	cytochrome c oxidase, subunit III	coxO	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SYD2_k127_4995027_1	1123248.KB893319_gene3966	1.725e-202	648.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1IPZE@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SYD2_k127_4995027_3	234267.Acid_5589	9.503e-74	257.0	COG1622@1|root,COG1622@2|Bacteria,3Y4UA@57723|Acidobacteria	57723|Acidobacteria	C	PFAM cytochrome c oxidase subunit II	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
SYD2_k127_4995027_2	1267535.KB906767_gene1277	2.223e-90	308.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria,2JIRB@204432|Acidobacteriia	204432|Acidobacteriia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SYD2_k127_4995027_6	671143.DAMO_1660	1.816e-47	183.0	COG1612@1|root,COG1612@2|Bacteria,2NQ3D@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259,ko:K03110	ko00190,ko00860,ko01100,ko01110,ko02020,ko02024,ko03060,ko03070,ko04714,map00190,map00860,map01100,map01110,map02020,map02024,map03060,map03070,map04714	M00154,M00335	R07412	RC00769	ko00000,ko00001,ko00002,ko02044,ko03029	3.A.5.1,3.A.5.2,3.A.5.7,3.D.4.4	-	-	COX15-CtaA
SYD2_k127_4995027_5	234267.Acid_4384	3.783e-59	215.0	COG3794@1|root,COG3794@2|Bacteria,3Y4A0@57723|Acidobacteria	57723|Acidobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SYD2_k127_4995027_0	234267.Acid_4385	2.64e-244	780.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,PA14
SYD2_k127_4995986_4	234267.Acid_7680	3.877e-90	304.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SYD2_k127_4995986_1	204669.Acid345_1052	4.401e-186	612.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SYD2_k127_4995986_2	204669.Acid345_2716	1.155e-160	541.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SYD2_k127_4995986_6	1144275.COCOR_02148	4.526e-59	222.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SYD2_k127_4995986_9	861299.J421_5972	1.531e-46	179.0	2BS4J@1|root,32M5G@2|Bacteria,1ZUJX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4995986_8	69395.JQLZ01000007_gene1770	1.061e-51	190.0	2BS4J@1|root,32M5G@2|Bacteria,1NU6I@1224|Proteobacteria,2UQIE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_4995986_11	234267.Acid_3938	5.211e-15	80.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SYD2_k127_4995986_5	861299.J421_1411	2.769e-80	286.0	COG1231@1|root,COG1231@2|Bacteria	2|Bacteria	E	oxidoreductase activity	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SYD2_k127_4995986_12	234267.Acid_7636	1.601e-08	61.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SYD2_k127_4995986_7	1267535.KB906767_gene341	1.568e-54	198.0	28JRZ@1|root,2Z9HI@2|Bacteria,3Y7HD@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
SYD2_k127_4995986_10	1541065.JRFE01000023_gene3739	3.853e-35	149.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SYD2_k127_4995986_3	383381.EH30_02410	5.584e-102	351.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria,2K2YU@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_8
SYD2_k127_4995986_0	1313421.JHBV01000003_gene663	8.453e-303	952.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1IQP1@117747|Sphingobacteriia	976|Bacteroidetes	G	Chitobiase/beta-hexosaminidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
SYD2_k127_503420_2	635013.TherJR_0752	5.88e-123	410.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,2608U@186807|Peptococcaceae	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SYD2_k127_503420_3	234267.Acid_7838	8.059e-52	206.0	COG4252@1|root,COG5002@1|root,COG4252@2|Bacteria,COG5002@2|Bacteria,3Y7KI@57723|Acidobacteria	57723|Acidobacteria	T	CHASE2	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,HATPase_c,HisKA
SYD2_k127_503420_0	886293.Sinac_0988	2.27e-217	685.0	COG0531@1|root,COG0531@2|Bacteria,2IX7G@203682|Planctomycetes	203682|Planctomycetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SYD2_k127_503420_4	1267535.KB906767_gene4113	4.694e-25	113.0	COG2940@1|root,COG2940@2|Bacteria,3Y7R1@57723|Acidobacteria	57723|Acidobacteria	S	SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
SYD2_k127_503420_1	706587.Desti_0542	3.744e-204	664.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria,2MQ7A@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
SYD2_k127_503420_5	204669.Acid345_3133	1.824e-24	116.0	COG0810@1|root,COG0810@2|Bacteria,3Y4BU@57723|Acidobacteria,2JJ3R@204432|Acidobacteriia	204432|Acidobacteriia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
SYD2_k127_5038775_0	1396141.BATP01000059_gene2564	2.663e-148	472.0	COG0388@1|root,COG0388@2|Bacteria,46S7B@74201|Verrucomicrobia,2ITNA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SYD2_k127_5038775_6	266940.Krad_2669	1.659e-45	169.0	COG0251@1|root,COG0251@2|Bacteria,2IIB2@201174|Actinobacteria	201174|Actinobacteria	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SYD2_k127_5038775_2	391625.PPSIR1_32307	4.097e-137	445.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,42YD3@68525|delta/epsilon subdivisions,2WTVV@28221|Deltaproteobacteria,2YU0M@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	yeiA	-	1.3.1.1	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21
SYD2_k127_5038775_3	1267534.KB906759_gene1889	7.496e-120	406.0	COG0671@1|root,COG0671@2|Bacteria,3Y6DG@57723|Acidobacteria	57723|Acidobacteria	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5038775_7	1248917.ANFX01000032_gene927	1.815e-23	110.0	2AZX3@1|root,31S6U@2|Bacteria,1RJH6@1224|Proteobacteria,2UDV0@28211|Alphaproteobacteria,2K6BJ@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4328
SYD2_k127_5038775_5	1183438.GKIL_1098	1.927e-94	317.0	COG0708@1|root,COG0708@2|Bacteria,1G29X@1117|Cyanobacteria	1117|Cyanobacteria	L	Exodeoxyribonuclease iii	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SYD2_k127_5038775_4	309801.trd_1459	1.387e-95	326.0	COG0624@1|root,COG0624@2|Bacteria,2G60R@200795|Chloroflexi,27Y02@189775|Thermomicrobia	189775|Thermomicrobia	E	peptidase dimerisation domain protein	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SYD2_k127_5038775_1	234267.Acid_1847	5.702e-138	447.0	COG4948@1|root,COG4948@2|Bacteria,3Y2QQ@57723|Acidobacteria	57723|Acidobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SYD2_k127_5038775_8	1121920.AUAU01000007_gene535	8.652e-06	59.0	COG0457@1|root,COG0457@2|Bacteria	1121920.AUAU01000007_gene535|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5054457_0	204669.Acid345_1048	1.369e-252	786.0	COG2987@1|root,COG2987@2|Bacteria,3Y2VD@57723|Acidobacteria,2JK4Z@204432|Acidobacteriia	204432|Acidobacteriia	E	Urocanase Rossmann-like domain	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SYD2_k127_5054457_1	861299.J421_1513	2.855e-38	150.0	2CWY1@1|root,32T0M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5057781_0	749414.SBI_06169	6.925e-288	899.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SYD2_k127_5057781_2	706587.Desti_5258	7.185e-63	220.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,2MRJC@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SYD2_k127_5057781_1	204669.Acid345_1221	1.187e-66	228.0	COG0048@1|root,COG0048@2|Bacteria,3Y4JQ@57723|Acidobacteria,2JJ7D@204432|Acidobacteriia	204432|Acidobacteriia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SYD2_k127_5057781_3	373994.Riv7116_5215	7.629e-14	81.0	COG0457@1|root,COG1196@1|root,COG0457@2|Bacteria,COG1196@2|Bacteria,1G1U5@1117|Cyanobacteria,1HJ1H@1161|Nostocales	1117|Cyanobacteria	M	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SYD2_k127_5060137_4	290512.Paes_1799	7.104e-07	57.0	29GCI@1|root,303AD@2|Bacteria,1FE3Q@1090|Chlorobi	1090|Chlorobi	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
SYD2_k127_5060137_1	96561.Dole_3045	7.096e-78	270.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,2MITP@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SYD2_k127_5060137_2	204669.Acid345_0064	4.478e-70	243.0	COG0465@1|root,COG0465@2|Bacteria,3Y2UK@57723|Acidobacteria,2JI9D@204432|Acidobacteriia	204432|Acidobacteriia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SYD2_k127_5060137_0	1382359.JIAL01000001_gene416	1.969e-181	577.0	COG0465@1|root,COG0465@2|Bacteria,3Y2UK@57723|Acidobacteria,2JI9D@204432|Acidobacteriia	204432|Acidobacteriia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SYD2_k127_5060137_3	443143.GM18_2519	1.509e-43	173.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,43U6A@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
SYD2_k127_5077551_25	338963.Pcar_1256	1.371e-48	179.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,43T3I@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA,GFO_IDH_MocA_C
SYD2_k127_5077551_23	404380.Gbem_2984	3.533e-54	211.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,42RXF@68525|delta/epsilon subdivisions,2WNF1@28221|Deltaproteobacteria,43TBY@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 39	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
SYD2_k127_5077551_42	679935.Alfi_0928	5.727e-05	54.0	COG1073@1|root,COG1073@2|Bacteria,4NJY1@976|Bacteroidetes,2FMHJ@200643|Bacteroidia	976|Bacteroidetes	S	of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S9
SYD2_k127_5077551_28	243231.GSU3147	8.099e-31	137.0	COG0746@1|root,COG1763@1|root,COG0746@2|Bacteria,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,42RZK@68525|delta/epsilon subdivisions,2WQ3C@28221|Deltaproteobacteria,43SFT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobB	-	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
SYD2_k127_5077551_11	204669.Acid345_3562	9.806e-100	353.0	COG1044@1|root,COG1044@2|Bacteria,3Y2ZS@57723|Acidobacteria,2JIC3@204432|Acidobacteriia	204432|Acidobacteriia	M	SpoIVB peptidase S55	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
SYD2_k127_5077551_31	748280.NH8B_3797	3.03e-23	107.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria,2KQMA@206351|Neisseriales	206351|Neisseriales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	gidB	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SYD2_k127_5077551_15	1278073.MYSTI_05417	6.096e-86	303.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2YWPS@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SYD2_k127_5077551_9	661478.OP10G_1859	1.025e-115	388.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SYD2_k127_5077551_21	661478.OP10G_1859	3.045e-61	215.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SYD2_k127_5077551_17	886293.Sinac_2397	8.61e-80	275.0	COG1028@1|root,COG1028@2|Bacteria	886293.Sinac_2397|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.3.1.34	ko:K13237	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	-
SYD2_k127_5077551_4	269799.Gmet_2497	1.19e-135	447.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,43TZF@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SYD2_k127_5077551_27	234267.Acid_5500	4.888e-37	148.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	HemolysinCabind,Pro_isomerase
SYD2_k127_5077551_16	240015.ACP_2879	1.25e-80	273.0	COG0512@1|root,COG0512@2|Bacteria,3Y36D@57723|Acidobacteria,2JHQS@204432|Acidobacteriia	204432|Acidobacteriia	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SYD2_k127_5077551_13	1121468.AUBR01000014_gene2225	2.662e-93	318.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,42EK5@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SYD2_k127_5077551_12	1382306.JNIM01000001_gene2650	1.349e-97	336.0	COG0134@1|root,COG0135@1|root,COG0134@2|Bacteria,COG0135@2|Bacteria,2G6GG@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PRAI
SYD2_k127_5077551_14	1313301.AUGC01000004_gene2357	1.867e-91	308.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
SYD2_k127_5077551_10	234267.Acid_7397	8.784e-107	365.0	COG1508@1|root,COG1508@2|Bacteria,3Y2M0@57723|Acidobacteria	57723|Acidobacteria	K	RNA polymerase sigma-54 factor	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
SYD2_k127_5077551_29	1499967.BAYZ01000065_gene6104	5.303e-30	125.0	COG1544@1|root,COG1544@2|Bacteria,2NPYS@2323|unclassified Bacteria	2|Bacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
SYD2_k127_5077551_18	404589.Anae109_0152	1.399e-76	267.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,42MZM@68525|delta/epsilon subdivisions,2WJG6@28221|Deltaproteobacteria,2YV1E@29|Myxococcales	28221|Deltaproteobacteria	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SYD2_k127_5077551_30	1047013.AQSP01000135_gene1606	2.568e-27	118.0	COG2893@1|root,COG2893@2|Bacteria,2NRCX@2323|unclassified Bacteria	2|Bacteria	G	PTS system fructose IIA component	manX	-	2.7.1.191,2.7.1.194	ko:K02793,ko:K02794,ko:K02821	ko00051,ko00053,ko00520,ko01100,ko01120,ko02060,map00051,map00053,map00520,map01100,map01120,map02060	M00276,M00283,M00550	R02630,R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.7.1	-	-	EIIA-man
SYD2_k127_5077551_38	1267535.KB906767_gene4348	6.24e-09	64.0	2AWP9@1|root,31NK6@2|Bacteria	2|Bacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Gal-3-0_sulfotr,Sulfotransfer_2
SYD2_k127_5077551_40	319225.Plut_0757	9.761e-06	55.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SYD2_k127_5077551_0	316274.Haur_2328	1.659e-169	543.0	COG2270@1|root,COG2270@2|Bacteria,2G633@200795|Chloroflexi,374W1@32061|Chloroflexia	32061|Chloroflexia	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
SYD2_k127_5077551_22	1408422.JHYF01000009_gene1999	6.173e-61	222.0	COG3635@1|root,COG3635@2|Bacteria,1UIDA@1239|Firmicutes,25EIA@186801|Clostridia	186801|Clostridia	G	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme
SYD2_k127_5077551_7	204669.Acid345_3274	9.531e-122	406.0	COG2204@1|root,COG2204@2|Bacteria,3Y3HH@57723|Acidobacteria,2JI5D@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SYD2_k127_5077551_36	880073.Calab_3721	2.615e-14	83.0	COG1587@1|root,COG1587@2|Bacteria,2NS43@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen-III synthase HemD	hemD	-	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SYD2_k127_5077551_26	395961.Cyan7425_4907	4.467e-43	165.0	COG0586@1|root,COG0586@2|Bacteria,1G184@1117|Cyanobacteria,3KFR2@43988|Cyanothece	1117|Cyanobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
SYD2_k127_5077551_34	240015.ACP_2773	4.433e-19	101.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria,2JHV1@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
SYD2_k127_5077551_19	639282.DEFDS_1810	2.513e-70	243.0	COG2316@1|root,COG2316@2|Bacteria,2GFCZ@200930|Deferribacteres	200930|Deferribacteres	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SYD2_k127_5077551_8	1242864.D187_004986	1.363e-121	396.0	COG0506@1|root,COG0506@2|Bacteria,1R8VR@1224|Proteobacteria,42P21@68525|delta/epsilon subdivisions,2WJU2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SYD2_k127_5077551_33	1278073.MYSTI_03931	1.984e-19	94.0	COG1585@1|root,COG1585@2|Bacteria,1NG8Q@1224|Proteobacteria,42WTA@68525|delta/epsilon subdivisions,2WSVK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
SYD2_k127_5077551_39	380749.HY04AAS1_1164	4.412e-08	64.0	COG0265@1|root,COG0265@2|Bacteria,2G3MU@200783|Aquificae	200783|Aquificae	M	PFAM peptidase S1 and S6 chymotrypsin Hap	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SYD2_k127_5077551_20	861299.J421_2843	1.488e-63	229.0	COG0631@1|root,COG0631@2|Bacteria,1ZT1X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SYD2_k127_5077551_2	240015.ACP_1006	9.762e-155	496.0	COG0626@1|root,COG0626@2|Bacteria,3Y2K5@57723|Acidobacteria,2JHVD@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.1,4.4.1.2,4.4.1.8	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00609	R00782,R01001,R01283,R01286,R02408,R04941	RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SYD2_k127_5077551_41	378806.STAUR_3252	1.841e-05	52.0	COG3215@1|root,COG3215@2|Bacteria,1Q2S4@1224|Proteobacteria,43266@68525|delta/epsilon subdivisions,2WXR8@28221|Deltaproteobacteria,2YVFJ@29|Myxococcales	28221|Deltaproteobacteria	NU	PilZ domain	-	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
SYD2_k127_5077551_3	1121957.ATVL01000009_gene1201	2.277e-154	496.0	COG2170@1|root,COG2170@2|Bacteria,4NFFP@976|Bacteroidetes,47KG2@768503|Cytophagia	976|Bacteroidetes	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SYD2_k127_5077551_32	102125.Xen7305DRAFT_00006210	1.033e-20	96.0	COG3041@1|root,COG3041@2|Bacteria,1G7V7@1117|Cyanobacteria,3VMW8@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Plasmid maintenance system killer protein	-	-	-	-	-	-	-	-	-	-	-	-	YafQ_toxin
SYD2_k127_5077551_43	1541065.JRFE01000017_gene120	0.0005446	45.0	2CD53@1|root,32Y16@2|Bacteria,1G9GR@1117|Cyanobacteria,3VKIH@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5077551_24	1499967.BAYZ01000060_gene6005	1.059e-52	194.0	COG0122@1|root,COG0122@2|Bacteria	2|Bacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SYD2_k127_5077551_37	634498.mru_1422	5.535e-12	76.0	COG0518@1|root,arCOG00087@2157|Archaea,2XT3G@28890|Euryarchaeota,23NYX@183925|Methanobacteria	183925|Methanobacteria	F	Catalyzes the synthesis of GMP from XMP	guaAA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
SYD2_k127_5077551_6	316067.Geob_0475	1.54e-130	433.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SYD2_k127_5077551_35	997346.HMPREF9374_1056	2.958e-15	85.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,27C3S@186824|Thermoactinomycetaceae	91061|Bacilli	CO	Glutathione peroxidase	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SYD2_k127_5077551_1	1125863.JAFN01000001_gene2409	5.589e-162	525.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SYD2_k127_5077551_5	1125863.JAFN01000001_gene2410	5.332e-131	436.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SYD2_k127_5079319_30	1382359.JIAL01000001_gene1440	1.134e-07	58.0	2BE84@1|root,327Z4@2|Bacteria,3Y51A@57723|Acidobacteria,2JJKM@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5079319_23	1094715.CM001373_gene3146	2.85e-18	96.0	COG0823@1|root,COG0823@2|Bacteria,1QM87@1224|Proteobacteria,1TH3S@1236|Gammaproteobacteria,1JDAV@118969|Legionellales	118969|Legionellales	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SYD2_k127_5079319_28	589865.DaAHT2_1302	5.502e-08	60.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2MHKY@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SYD2_k127_5079319_9	1173026.Glo7428_4658	8.668e-72	254.0	arCOG10178@1|root,2ZAAA@2|Bacteria,1G4AM@1117|Cyanobacteria	1117|Cyanobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SYD2_k127_5079319_4	190650.CC_3179	6.042e-98	330.0	COG2159@1|root,COG2159@2|Bacteria,1PTY1@1224|Proteobacteria,2V5RF@28211|Alphaproteobacteria,2KHVI@204458|Caulobacterales	204458|Caulobacterales	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SYD2_k127_5079319_8	861299.J421_3685	9.26e-77	262.0	COG0231@1|root,COG0231@2|Bacteria,1ZT2N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SYD2_k127_5079319_24	1198114.AciX9_0841	1.362e-17	88.0	COG1519@1|root,COG1519@2|Bacteria,3Y3X5@57723|Acidobacteria,2JI61@204432|Acidobacteriia	204432|Acidobacteriia	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
SYD2_k127_5079319_12	1123261.AXDW01000003_gene1915	6.867e-62	225.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1X4GI@135614|Xanthomonadales	135614|Xanthomonadales	M	transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
SYD2_k127_5079319_13	269799.Gmet_2347	6.907e-62	227.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2WNJ4@28221|Deltaproteobacteria,43SX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
SYD2_k127_5079319_10	1242864.D187_010069	1.221e-71	262.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
SYD2_k127_5079319_27	765869.BDW_00050	9.544e-11	70.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42VAI@68525|delta/epsilon subdivisions,2MTDA@213481|Bdellovibrionales,2WRI4@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SYD2_k127_5079319_17	671143.DAMO_2702	2.097e-42	168.0	COG0356@1|root,COG0356@2|Bacteria,2NPRQ@2323|unclassified Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SYD2_k127_5079319_7	997829.HMPREF1121_01052	2.383e-87	302.0	COG0330@1|root,COG0330@2|Bacteria,4NH8V@976|Bacteroidetes,2FQPC@200643|Bacteroidia,22Z0Q@171551|Porphyromonadaceae	976|Bacteroidetes	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SYD2_k127_5079319_3	1267534.KB906754_gene2899	1.387e-100	346.0	COG0154@1|root,COG0154@2|Bacteria,3Y41H@57723|Acidobacteria,2JKKU@204432|Acidobacteriia	204432|Acidobacteriia	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SYD2_k127_5079319_1	1198114.AciX9_1376	1.369e-143	462.0	COG0039@1|root,COG0039@2|Bacteria,3Y2PG@57723|Acidobacteria,2JII1@204432|Acidobacteriia	204432|Acidobacteriia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SYD2_k127_5079319_25	1121447.JONL01000008_gene3531	8.313e-16	82.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2MBWU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SYD2_k127_5079319_15	1382359.JIAL01000001_gene123	6.946e-56	204.0	COG1451@1|root,COG1451@2|Bacteria,3Y2SM@57723|Acidobacteria,2JHKB@204432|Acidobacteriia	204432|Acidobacteriia	S	nucleotide metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5079319_11	671143.DAMO_2256	1.297e-70	254.0	COG1420@1|root,COG1420@2|Bacteria,2NPAK@2323|unclassified Bacteria	2|Bacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA,HrcA_DNA-bdg
SYD2_k127_5079319_19	586416.GZ22_09490	2.379e-26	118.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SYD2_k127_5079319_0	338963.Pcar_0107	5.956e-229	723.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,43TCM@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SYD2_k127_5079319_2	265072.Mfla_0750	1.078e-124	410.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,2KKPJ@206350|Nitrosomonadales	206350|Nitrosomonadales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SYD2_k127_5079319_5	1379270.AUXF01000004_gene3236	2.124e-97	334.0	COG0402@1|root,COG0402@2|Bacteria,1ZSMH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SYD2_k127_5079319_21	481448.Minf_0099	4.533e-24	108.0	COG0741@1|root,COG0741@2|Bacteria,46W79@74201|Verrucomicrobia,37GKP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Transglycosylase SLT domain	mltE	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
SYD2_k127_5079319_22	388467.A19Y_2179	5.21e-23	104.0	COG1848@1|root,COG1848@2|Bacteria,1G51H@1117|Cyanobacteria,1HAWH@1150|Oscillatoriales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SYD2_k127_5079319_29	1183438.GKIL_4114	1.129e-07	64.0	COG3577@1|root,COG3577@2|Bacteria,1G044@1117|Cyanobacteria	1117|Cyanobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	gag-asp_proteas
SYD2_k127_5079319_18	673860.AciM339_0567	2.757e-33	137.0	COG1059@1|root,arCOG04357@2157|Archaea,2XWSZ@28890|Euryarchaeota,3F2WU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)	ogg	-	4.2.99.18	ko:K03653	-	-	-	-	ko00000,ko01000	-	-	-	-
SYD2_k127_5079319_16	41431.PCC8801_1807	3.273e-48	190.0	COG2027@1|root,COG2027@2|Bacteria,1G06E@1117|Cyanobacteria,3KGY1@43988|Cyanothece	1117|Cyanobacteria	M	PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SYD2_k127_5079319_14	204669.Acid345_1588	2.442e-56	201.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria,2JKV3@204432|Acidobacteriia	204432|Acidobacteriia	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SYD2_k127_5104409_1	682795.AciX8_0352	2.78e-78	265.0	COG0535@1|root,COG0535@2|Bacteria,3Y3QA@57723|Acidobacteria,2JIAZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SYD2_k127_5104409_2	1382359.JIAL01000001_gene804	2.286e-76	262.0	COG1136@1|root,COG1136@2|Bacteria,3Y3JD@57723|Acidobacteria,2JIHH@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SYD2_k127_5104409_3	204669.Acid345_0559	6.189e-44	174.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,LolA_like,MacB_PCD
SYD2_k127_5104409_4	278963.ATWD01000001_gene3234	1.531e-08	66.0	COG2834@1|root,COG2834@2|Bacteria,3Y4A1@57723|Acidobacteria,2JJ5F@204432|Acidobacteriia	204432|Acidobacteriia	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
SYD2_k127_5104409_6	204669.Acid345_3273	2.95e-07	61.0	2EK74@1|root,33DXH@2|Bacteria,3Y5VZ@57723|Acidobacteria,2JK2Y@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5104409_0	234267.Acid_3616	4.866e-164	526.0	COG0436@1|root,COG0436@2|Bacteria,3Y2TF@57723|Acidobacteria	57723|Acidobacteria	E	PFAM aminotransferase, class I	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SYD2_k127_5104409_7	357808.RoseRS_0659	8.383e-05	51.0	COG0457@1|root,COG5427@1|root,COG0457@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi,37551@32061|Chloroflexia	32061|Chloroflexia	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
SYD2_k127_5110273_5	1122221.JHVI01000021_gene2447	4.496e-28	127.0	COG5542@1|root,COG5542@2|Bacteria	2|Bacteria	O	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	GT87,Mannosyl_trans2,PMT_2
SYD2_k127_5110273_6	246969.TAM4_2190	3.741e-09	69.0	COG0500@1|root,arCOG04347@2157|Archaea,2XWKC@28890|Euryarchaeota,243JY@183968|Thermococci	183968|Thermococci	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SYD2_k127_5110273_1	234267.Acid_4413	1.318e-114	383.0	COG1134@1|root,COG1134@2|Bacteria,3Y72D@57723|Acidobacteria	57723|Acidobacteria	GM	Wzt C-terminal domain	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
SYD2_k127_5110273_3	1128427.KB904821_gene2716	3.442e-82	280.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SYD2_k127_5110273_0	1128427.KB904821_gene2717	2.508e-135	439.0	28KU8@1|root,2ZCM9@2|Bacteria,1G5AX@1117|Cyanobacteria,1HAQ7@1150|Oscillatoriales	1117|Cyanobacteria	S	STELLO glycosyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	STELLO
SYD2_k127_5110273_7	671143.DAMO_2857	0.0005043	53.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SYD2_k127_5110273_4	639030.JHVA01000001_gene2882	1.944e-33	144.0	COG1452@1|root,COG1452@2|Bacteria,3Y37B@57723|Acidobacteria,2JHPP@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Organic solvent tolerance protein	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA_C
SYD2_k127_5118353_4	563192.HMPREF0179_02695	0.0003229	52.0	2EU62@1|root,33MNN@2|Bacteria,1P70U@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
SYD2_k127_5118353_1	1173027.Mic7113_5049	2.158e-102	367.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H8D7@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_1,TPR_10,TPR_12,TPR_7,TPR_8
SYD2_k127_5118353_0	768670.Calni_0847	6.464e-154	528.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,2GG9I@200930|Deferribacteres	200930|Deferribacteres	G	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
SYD2_k127_5118353_2	357808.RoseRS_3392	6.763e-69	256.0	COG1413@1|root,COG1413@2|Bacteria,2G6UU@200795|Chloroflexi	200795|Chloroflexi	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SYD2_k127_5118353_3	756272.Plabr_1950	5.631e-25	120.0	COG1413@1|root,COG3391@1|root,COG1413@2|Bacteria,COG3391@2|Bacteria,2IXTT@203682|Planctomycetes	203682|Planctomycetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SYD2_k127_5124999_0	861299.J421_0666	4.067e-161	514.0	COG4447@1|root,COG4447@2|Bacteria,1ZSWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5124999_4	1255043.TVNIR_1423	0.0002172	51.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,1WYXH@135613|Chromatiales	135613|Chromatiales	S	PFAM YCII-related	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
SYD2_k127_5124999_3	1565129.JSFF01000028_gene720	3.644e-21	102.0	COG2350@1|root,COG2350@2|Bacteria,1NCHB@1224|Proteobacteria,1SG2M@1236|Gammaproteobacteria,2QC74@267890|Shewanellaceae	1236|Gammaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SYD2_k127_5124999_2	706587.Desti_0428	1.088e-58	210.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,42RIQ@68525|delta/epsilon subdivisions,2WNC7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM PEBP family protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SYD2_k127_5124999_1	439235.Dalk_4968	9.006e-78	270.0	COG4581@1|root,COG4581@2|Bacteria,1QUPR@1224|Proteobacteria,42NSH@68525|delta/epsilon subdivisions,2WKD7@28221|Deltaproteobacteria,2MHX7@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,DUF3516,Helicase_C
SYD2_k127_5132455_6	234267.Acid_3868	1.226e-17	83.0	COG0053@1|root,COG0053@2|Bacteria,3Y5VF@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SYD2_k127_5132455_0	234267.Acid_2509	1.085e-158	533.0	COG0744@1|root,COG0744@2|Bacteria	2|Bacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mrcB	-	2.4.1.129,3.4.16.4	ko:K03814,ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
SYD2_k127_5132455_5	1121439.dsat_2287	1.077e-24	107.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2WJBU@28221|Deltaproteobacteria,2M82B@213115|Desulfovibrionales	28221|Deltaproteobacteria	CO	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	nifU	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
SYD2_k127_5132455_2	768710.DesyoDRAFT_0866	2.803e-129	424.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25ZZ7@186807|Peptococcaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SYD2_k127_5132455_7	1267533.KB906739_gene2548	3.721e-07	61.0	COG2948@1|root,COG2948@2|Bacteria,3Y81Q@57723|Acidobacteria,2JN9S@204432|Acidobacteriia	204432|Acidobacteriia	U	multi-organism process	-	-	-	ko:K03195	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbI
SYD2_k127_5132455_3	234267.Acid_0601	2.525e-63	227.0	COG1912@1|root,COG1912@2|Bacteria,3Y50E@57723|Acidobacteria	57723|Acidobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SYD2_k127_5132455_1	562970.Btus_2368	1.958e-137	447.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,278TC@186823|Alicyclobacillaceae	91061|Bacilli	C	Citrate synthase, C-terminal domain	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SYD2_k127_5132455_4	794903.OPIT5_20675	1.271e-41	158.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N,SIS
SYD2_k127_5152861_1	429009.Adeg_1094	1.045e-180	580.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,42F6C@68295|Thermoanaerobacterales	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SYD2_k127_5152861_14	426114.THI_1455	5.703e-06	54.0	2EIG1@1|root,33C7D@2|Bacteria,1NNA9@1224|Proteobacteria,2W607@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5152861_13	1292035.H476_3046	6.494e-07	56.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,25S3J@186804|Peptostreptococcaceae	186801|Clostridia	KT	Bacterial regulatory protein, Fis family	prdR	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
SYD2_k127_5152861_9	1121472.AQWN01000004_gene782	8.322e-46	179.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia,261DG@186807|Peptococcaceae	186801|Clostridia	S	Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
SYD2_k127_5152861_4	234267.Acid_3254	6.613e-77	273.0	COG4783@1|root,COG4783@2|Bacteria,3Y3GF@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SYD2_k127_5152861_11	1499967.BAYZ01000080_gene947	2.981e-38	153.0	COG0558@1|root,COG0558@2|Bacteria,2NPJ9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iIT341.HP1016	CDP-OH_P_transf
SYD2_k127_5152861_0	234267.Acid_7263	0.0	1229.0	COG0178@1|root,COG0178@2|Bacteria,3Y3G9@57723|Acidobacteria	57723|Acidobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SYD2_k127_5152861_10	1519464.HY22_02245	1.105e-41	160.0	COG4914@1|root,COG4914@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
SYD2_k127_5152861_8	869210.Marky_1654	8.614e-55	198.0	COG0279@1|root,COG0279@2|Bacteria,1WMGK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
SYD2_k127_5152861_3	330214.NIDE4314	1.411e-96	326.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5152861_5	1173026.Glo7428_1817	1.018e-76	264.0	COG0730@1|root,COG0730@2|Bacteria,1G72I@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SYD2_k127_5152861_12	671143.DAMO_0335	9.071e-15	79.0	COG1734@1|root,COG1734@2|Bacteria,2NQ6S@2323|unclassified Bacteria	2|Bacteria	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SYD2_k127_5152861_6	1267533.KB906733_gene3211	2.714e-74	253.0	COG0221@1|root,COG0221@2|Bacteria,3Y3UZ@57723|Acidobacteria,2JIJK@204432|Acidobacteriia	204432|Acidobacteriia	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SYD2_k127_5152861_7	240015.ACP_1819	3.783e-59	215.0	COG1484@1|root,COG1484@2|Bacteria,3Y3EK@57723|Acidobacteria,2JI9M@204432|Acidobacteriia	204432|Acidobacteriia	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
SYD2_k127_5152861_2	1382359.JIAL01000001_gene3036	1.09e-100	335.0	COG0308@1|root,COG0308@2|Bacteria,3Y3ZS@57723|Acidobacteria,2JK79@204432|Acidobacteriia	204432|Acidobacteriia	E	Phospholipase B	-	-	-	-	-	-	-	-	-	-	-	-	Phospholip_B
SYD2_k127_5160188_3	945713.IALB_2894	1.448e-84	283.0	COG0396@1|root,COG0396@2|Bacteria	2|Bacteria	O	ATPase activity	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	ABC_tran
SYD2_k127_5160188_0	1487953.JMKF01000065_gene4700	8.889e-255	791.0	COG0719@1|root,COG0719@2|Bacteria,1G0TH@1117|Cyanobacteria,1H8CG@1150|Oscillatoriales	1117|Cyanobacteria	O	COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SYD2_k127_5160188_8	234267.Acid_7705	8.872e-24	107.0	COG1959@1|root,COG1959@2|Bacteria,3Y7VG@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SYD2_k127_5160188_4	682795.AciX8_3966	2.676e-84	295.0	COG0642@1|root,COG2205@2|Bacteria,3Y2W3@57723|Acidobacteria,2JIDP@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
SYD2_k127_5160188_5	1267533.KB906735_gene4781	2.011e-72	251.0	COG0745@1|root,COG0745@2|Bacteria,3Y4R4@57723|Acidobacteria,2JJBD@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator, receiver	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SYD2_k127_5160188_7	1396141.BATP01000004_gene5936	4.248e-29	119.0	COG1943@1|root,COG1943@2|Bacteria,46VP6@74201|Verrucomicrobia,2IVSQ@203494|Verrucomicrobiae	74201|Verrucomicrobia	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SYD2_k127_5160188_1	1128421.JAGA01000002_gene269	1.071e-198	639.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SYD2_k127_5160188_2	234267.Acid_5235	3.197e-151	492.0	COG0402@1|root,COG0402@2|Bacteria,3Y64N@57723|Acidobacteria	57723|Acidobacteria	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SYD2_k127_5160188_6	234267.Acid_5234	2.518e-39	151.0	COG0295@1|root,COG0295@2|Bacteria,3Y5GE@57723|Acidobacteria	57723|Acidobacteria	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
SYD2_k127_5175529_2	1297865.APJD01000028_gene5192	1.038e-104	349.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2TU6T@28211|Alphaproteobacteria,3JX4C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SYD2_k127_5175529_6	760192.Halhy_4969	4.177e-38	149.0	2D4D1@1|root,32TGT@2|Bacteria,4NUAV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5175529_5	1123278.KB893581_gene962	4.255e-42	158.0	COG0346@1|root,COG0346@2|Bacteria,4NRR7@976|Bacteroidetes,47QT0@768503|Cytophagia	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SYD2_k127_5175529_4	1168065.DOK_00682	7.328e-44	168.0	29NNR@1|root,31FC3@2|Bacteria,1R39F@1224|Proteobacteria,1T656@1236|Gammaproteobacteria,1JA0H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5175529_3	1354722.JQLS01000001_gene4845	3.8e-61	214.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	iorA	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SYD2_k127_5175529_1	1354722.JQLS01000001_gene4844	3.557e-241	767.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,46RIA@74030|Roseovarius	28211|Alphaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
SYD2_k127_5175529_0	118161.KB235922_gene2360	3.905e-242	762.0	COG1680@1|root,COG1680@2|Bacteria,1G5M7@1117|Cyanobacteria	1117|Cyanobacteria	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SYD2_k127_5175529_7	861299.J421_2299	8.226e-05	45.0	COG4127@1|root,COG4127@2|Bacteria,1ZV3T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat
SYD2_k127_5176459_2	401053.AciPR4_4001	1.138e-14	82.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria,2JI38@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SYD2_k127_5176459_1	555088.DealDRAFT_1853	1.177e-45	171.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,42JZE@68298|Syntrophomonadaceae	186801|Clostridia	H	Probable molybdopterin binding domain	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
SYD2_k127_5176459_0	639030.JHVA01000001_gene253	0.0	1127.0	COG0458@1|root,COG0458@2|Bacteria,3Y3GG@57723|Acidobacteria,2JIJZ@204432|Acidobacteriia	204432|Acidobacteriia	F	TIGRFAM carbamoyl-phosphate synthase, large subunit	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SYD2_k127_5182843_0	926550.CLDAP_09490	3.88e-40	153.0	COG2313@1|root,COG2313@2|Bacteria,2G5KC@200795|Chloroflexi	200795|Chloroflexi	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
SYD2_k127_5182843_2	661478.OP10G_4286	1.931e-10	74.0	2EKVR@1|root,33EJ9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5182843_3	234267.Acid_5431	8.206e-07	62.0	COG1629@1|root,COG4771@2|Bacteria,3Y2GB@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SYD2_k127_5182843_1	192875.XP_004364585.1	5.333e-24	117.0	COG0666@1|root,KOG4177@2759|Eukaryota,39K4G@33154|Opisthokonta	33154|Opisthokonta	M	Ankyrin repeats (3 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
SYD2_k127_5202341_11	156889.Mmc1_0832	9.177e-23	97.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2TQP8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SYD2_k127_5202341_5	1267535.KB906767_gene2705	2.044e-51	183.0	COG0051@1|root,COG0051@2|Bacteria,3Y4V5@57723|Acidobacteria,2JJAS@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SYD2_k127_5202341_2	234267.Acid_5118	6.474e-67	235.0	COG0087@1|root,COG0087@2|Bacteria,3Y2H7@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SYD2_k127_5202341_4	1499685.CCFJ01000033_gene33	3.101e-58	211.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,1ZBG9@1386|Bacillus	91061|Bacilli	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SYD2_k127_5202341_12	639030.JHVA01000001_gene1552	2.634e-22	99.0	COG0089@1|root,COG0089@2|Bacteria,3Y58W@57723|Acidobacteria,2JJR2@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SYD2_k127_5202341_0	1267535.KB906767_gene2701	9.534e-121	393.0	COG0090@1|root,COG0090@2|Bacteria,3Y3DH@57723|Acidobacteria,2JI2K@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SYD2_k127_5202341_7	363253.LI0964	1.198e-32	129.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,42THY@68525|delta/epsilon subdivisions,2WQ0F@28221|Deltaproteobacteria,2MBZW@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SYD2_k127_5202341_10	1198114.AciX9_2950	4.601e-25	112.0	COG0091@1|root,COG0091@2|Bacteria,3Y4KH@57723|Acidobacteria,2JJ8K@204432|Acidobacteriia	204432|Acidobacteriia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SYD2_k127_5202341_1	234267.Acid_5112	1.399e-92	309.0	COG0092@1|root,COG0092@2|Bacteria,3Y3ZN@57723|Acidobacteria	57723|Acidobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SYD2_k127_5202341_3	867903.ThesuDRAFT_00566	1.684e-64	223.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3WCGY@538999|Clostridiales incertae sedis	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SYD2_k127_5202341_14	1382359.JIAL01000001_gene1704	6.902e-09	59.0	COG0255@1|root,COG0255@2|Bacteria,3Y5KD@57723|Acidobacteria,2JK2D@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SYD2_k127_5202341_13	580340.Tlie_0655	4.591e-20	95.0	COG0186@1|root,COG0186@2|Bacteria,3TBG5@508458|Synergistetes	508458|Synergistetes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SYD2_k127_5202341_6	1382359.JIAL01000001_gene1706	1.172e-48	177.0	COG0093@1|root,COG0093@2|Bacteria,3Y4N0@57723|Acidobacteria,2JJ86@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SYD2_k127_5202341_8	1401328.P856_136	3.1e-26	111.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2UC6Y@28211|Alphaproteobacteria,2JT9D@204441|Rhodospirillales	204441|Rhodospirillales	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SYD2_k127_5202341_9	1267533.KB906735_gene5118	4.049e-25	106.0	COG0094@1|root,COG0094@2|Bacteria,3Y3PS@57723|Acidobacteria,2JHV4@204432|Acidobacteriia	204432|Acidobacteriia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SYD2_k127_5244861_2	1121957.ATVL01000009_gene937	1.662e-123	398.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,47KDS@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase family M3	-	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SYD2_k127_5244861_1	1267533.KB906737_gene1784	2.383e-291	911.0	COG0366@1|root,COG0366@2|Bacteria,3Y2IV@57723|Acidobacteria,2JHKG@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.135	ko:K21575	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_N
SYD2_k127_5244861_0	1519464.HY22_09715	2.638e-298	931.0	COG1505@1|root,COG1505@2|Bacteria	2|Bacteria	E	serine-type exopeptidase activity	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SYD2_k127_5244861_10	234267.Acid_6308	3.358e-19	100.0	COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SYD2_k127_5244861_11	338963.Pcar_1538	4.607e-13	81.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42MNP@68525|delta/epsilon subdivisions,2WMJZ@28221|Deltaproteobacteria,43T8T@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis/export protein	wza2	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SYD2_k127_5244861_4	7370.XP_005188234.1	3.373e-79	273.0	COG1028@1|root,KOG0725@2759|Eukaryota,38BUC@33154|Opisthokonta,3BC34@33208|Metazoa,3D09G@33213|Bilateria,41TU2@6656|Arthropoda,3SZ4C@50557|Insecta,454Z1@7147|Diptera	33208|Metazoa	Q	Oxidoreductase activity. It is involved in the biological process described with metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SYD2_k127_5244861_12	585425.KR52_08140	2.68e-11	77.0	COG0745@1|root,COG0745@2|Bacteria,1G2ME@1117|Cyanobacteria,1GYW6@1129|Synechococcus	1117|Cyanobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SYD2_k127_5244861_14	319795.Dgeo_2835	0.0002603	54.0	COG0457@1|root,COG0457@2|Bacteria	319795.Dgeo_2835|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5244861_3	42256.RradSPS_0832	3.938e-81	285.0	COG2339@1|root,COG2339@2|Bacteria,2GKR5@201174|Actinobacteria,4CU00@84995|Rubrobacteria	84995|Rubrobacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SYD2_k127_5244861_5	886293.Sinac_3059	6.413e-56	204.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	3.1.26.11,3.1.4.17	ko:K00784,ko:K01120	ko00230,ko03013,map00230,map03013	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000,ko03016	-	-	-	GAF,HD_5,Lactamase_B_2,PDEase_II
SYD2_k127_5244861_8	886293.Sinac_1403	6.972e-30	121.0	COG1146@1|root,COG1146@2|Bacteria,2J013@203682|Planctomycetes	203682|Planctomycetes	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
SYD2_k127_5244861_7	1121904.ARBP01000002_gene6681	6.87e-31	128.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
SYD2_k127_5244861_6	1499967.BAYZ01000039_gene2222	2.735e-54	200.0	COG0558@1|root,COG0558@2|Bacteria,2NPXW@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.34	ko:K07291	ko00562,map00562	-	R09670	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SYD2_k127_5244861_9	240015.ACP_2938	4.759e-28	115.0	2BYAI@1|root,315Y9@2|Bacteria,3Y52S@57723|Acidobacteria,2JJJK@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5244861_13	330214.NIDE2908	2.403e-08	55.0	COG3536@1|root,COG3536@2|Bacteria,3J1AV@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
SYD2_k127_5253460_5	234267.Acid_1174	3.626e-16	84.0	COG0210@1|root,COG0210@2|Bacteria,3Y2W8@57723|Acidobacteria	57723|Acidobacteria	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SYD2_k127_5253460_4	1267535.KB906767_gene2260	5.388e-18	93.0	COG3584@1|root,COG3584@2|Bacteria,3Y8W5@57723|Acidobacteria	57723|Acidobacteria	S	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
SYD2_k127_5253460_2	1122915.AUGY01000034_gene1003	1.19e-86	298.0	COG4448@1|root,COG4448@2|Bacteria,1TRWI@1239|Firmicutes,4HAM1@91061|Bacilli,26QWG@186822|Paenibacillaceae	91061|Bacilli	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SYD2_k127_5253460_0	1303518.CCALI_00899	1.035e-164	530.0	COG0423@1|root,COG0423@2|Bacteria	2|Bacteria	J	glycyl-tRNA aminoacylation	glyQS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iSB619.SA_RS07880	HGTP_anticodon,tRNA-synt_2b
SYD2_k127_5253460_3	1095769.CAHF01000015_gene2795	9.58e-36	139.0	COG4922@1|root,COG4922@2|Bacteria,1RDM5@1224|Proteobacteria,2VSBK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SYD2_k127_5253460_1	357808.RoseRS_2069	2.702e-163	524.0	COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi,375RR@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SYD2_k127_5260691_1	1267533.KB906741_gene405	1.023e-82	281.0	COG4638@1|root,COG4638@2|Bacteria,3Y547@57723|Acidobacteria,2JNCI@204432|Acidobacteriia	204432|Acidobacteriia	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
SYD2_k127_5260691_0	204669.Acid345_1269	7.346e-173	550.0	COG0404@1|root,COG0404@2|Bacteria,3Y3IU@57723|Acidobacteria,2JI8G@204432|Acidobacteriia	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SYD2_k127_5260691_4	234267.Acid_6539	1.551e-43	168.0	COG2930@1|root,COG2930@2|Bacteria,3Y2F0@57723|Acidobacteria	57723|Acidobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
SYD2_k127_5260691_3	767434.Fraau_3007	2.074e-48	181.0	COG2930@1|root,COG2930@2|Bacteria,1RHV6@1224|Proteobacteria,1SDNN@1236|Gammaproteobacteria,1X44C@135614|Xanthomonadales	135614|Xanthomonadales	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
SYD2_k127_5260691_2	880072.Desac_2905	2e-77	268.0	COG1876@1|root,COG3179@1|root,COG3409@1|root,COG1876@2|Bacteria,COG3179@2|Bacteria,COG3409@2|Bacteria,1N9AN@1224|Proteobacteria,42XYC@68525|delta/epsilon subdivisions,2WSN6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	peptidoglycan-binding domain-containing protein	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,VanY
SYD2_k127_5260691_7	1416759.AYMR01000007_gene697	0.0003327	52.0	COG3391@1|root,COG3468@1|root,COG4870@1|root,COG4932@1|root,COG3391@2|Bacteria,COG3468@2|Bacteria,COG4870@2|Bacteria,COG4932@2|Bacteria,2HCJX@201174|Actinobacteria,4FTDJ@85023|Microbacteriaceae	201174|Actinobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	TIG
SYD2_k127_5260691_5	1437882.AZRU01000042_gene4571	5.699e-30	132.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5263344_3	1499967.BAYZ01000026_gene1631	2.671e-104	356.0	COG0367@1|root,COG0367@2|Bacteria,2NNKE@2323|unclassified Bacteria	2|Bacteria	E	PFAM asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SYD2_k127_5263344_0	641524.ADICYQ_3561	1.633e-208	670.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,4NFEW@976|Bacteroidetes,47NZC@768503|Cytophagia	976|Bacteroidetes	E	Zinc-binding dehydrogenase	-	-	-	ko:K02030,ko:K03810	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	ADH_zinc_N,GFO_IDH_MocA
SYD2_k127_5263344_8	313589.JNB_16434	5.211e-21	95.0	COG4640@1|root,COG4640@2|Bacteria,2GSZE@201174|Actinobacteria,4FH41@85021|Intrasporangiaceae	201174|Actinobacteria	S	Interferon-induced transmembrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CD225
SYD2_k127_5263344_6	1173025.GEI7407_2746	2.286e-28	119.0	COG2314@1|root,COG2314@2|Bacteria,1G9J3@1117|Cyanobacteria,1HDPD@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
SYD2_k127_5263344_7	1148.1001250	2.574e-26	113.0	2E37T@1|root,32Y7G@2|Bacteria,1GECJ@1117|Cyanobacteria,1H68C@1142|Synechocystis	1117|Cyanobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
SYD2_k127_5263344_5	391625.PPSIR1_04398	2.777e-30	124.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,42RJS@68525|delta/epsilon subdivisions,2WQSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
SYD2_k127_5263344_4	215803.DB30_0292	2.426e-67	236.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2YXUH@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SYD2_k127_5263344_1	1382306.JNIM01000001_gene3484	1.217e-113	386.0	COG0365@1|root,COG0365@2|Bacteria	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	badA	-	6.2.1.25,6.2.1.27	ko:K04105,ko:K04110	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R01300,R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SYD2_k127_5263344_2	1469245.JFBG01000027_gene1490	5.703e-109	368.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1WWKR@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SYD2_k127_5273136_3	335543.Sfum_2411	1.237e-39	154.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MR9A@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SYD2_k127_5273136_4	406124.ACPC01000018_gene2603	0.0007876	47.0	29S8N@1|root,30DD4@2|Bacteria,1UB5Q@1239|Firmicutes,4IMIC@91061|Bacilli,1ZK7X@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5273136_2	1125863.JAFN01000001_gene1724	2.341e-62	224.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
SYD2_k127_5273136_0	234267.Acid_5526	4.634e-231	726.0	COG1032@1|root,COG1032@2|Bacteria,3Y2NI@57723|Acidobacteria	57723|Acidobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SYD2_k127_5273136_1	234267.Acid_5783	9.119e-92	323.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SYD2_k127_5288997_2	572547.Amico_0277	1.348e-13	83.0	COG1301@1|root,COG1301@2|Bacteria,3T9WV@508458|Synergistetes	508458|Synergistetes	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
SYD2_k127_5288997_1	388467.A19Y_0600	3.123e-47	181.0	COG0834@1|root,COG3409@1|root,COG0834@2|Bacteria,COG3409@2|Bacteria,1G48M@1117|Cyanobacteria,1H7C7@1150|Oscillatoriales	1117|Cyanobacteria	EMT	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SBP_bac_3
SYD2_k127_5288997_0	522306.CAP2UW1_2891	8.998e-82	279.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2VIN1@28216|Betaproteobacteria,1KR64@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	ET	PFAM extracellular solute-binding protein family 3	aapJ	-	-	ko:K02030,ko:K09969,ko:K10001	ko02010,ko02020,map02010,map02020	M00230,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.18,3.A.1.3.19,3.A.1.3.4,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
SYD2_k127_5292750_5	234267.Acid_5981	6.261e-82	285.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SYD2_k127_5292750_4	1340493.JNIF01000003_gene4032	6.227e-86	300.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SYD2_k127_5292750_2	99598.Cal7507_5457	2.039e-152	497.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1G1ZS@1117|Cyanobacteria,1HJFJ@1161|Nostocales	1117|Cyanobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SYD2_k127_5292750_3	251229.Chro_2426	2.481e-93	312.0	COG1125@1|root,COG1125@2|Bacteria,1G21Q@1117|Cyanobacteria,3VJTP@52604|Pleurocapsales	1117|Cyanobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
SYD2_k127_5292750_0	639030.JHVA01000001_gene250	4.62e-194	617.0	COG0148@1|root,COG0148@2|Bacteria,3Y2IT@57723|Acidobacteria,2JI6Q@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SYD2_k127_5292750_8	1379698.RBG1_1C00001G0743	6.603e-36	142.0	COG2318@1|root,COG2318@2|Bacteria,2NRHG@2323|unclassified Bacteria	2|Bacteria	S	DinB superfamily	dinB	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	DinB
SYD2_k127_5292750_6	926560.KE387023_gene1429	9.736e-53	191.0	COG0454@1|root,COG0454@2|Bacteria,1WMQ1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
SYD2_k127_5292750_1	264732.Moth_0265	3.482e-178	571.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,42FP5@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
SYD2_k127_5292750_7	518766.Rmar_0955	7.185e-47	179.0	28M67@1|root,31CRD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5327016_4	592029.DDD_0049	1.199e-43	161.0	COG3738@1|root,COG3738@2|Bacteria,4NM46@976|Bacteroidetes,1I1JU@117743|Flavobacteriia,3HK83@363408|Nonlabens	976|Bacteroidetes	S	Domain of unknown function (DUF1287)	-	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
SYD2_k127_5327016_5	314254.OA2633_04066	4.649e-37	143.0	COG4319@1|root,COG4319@2|Bacteria,1MZRB@1224|Proteobacteria,2UK7M@28211|Alphaproteobacteria,440N5@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
SYD2_k127_5327016_2	861299.J421_1133	7.094e-146	477.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	gadC	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039	-	ko:K20265	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.3.7.1,2.A.3.7.3	-	iEC042_1314.EC042_1624	AA_permease_2
SYD2_k127_5327016_1	1382359.JIAL01000001_gene2085	2.225e-160	516.0	COG1228@1|root,COG1228@2|Bacteria,3Y3BK@57723|Acidobacteria,2JKVY@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SYD2_k127_5327016_0	1163407.UU7_03772	0.0	1161.0	COG0726@1|root,COG1215@1|root,COG3858@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,COG3858@2|Bacteria,1MXG7@1224|Proteobacteria,1RMS4@1236|Gammaproteobacteria,1X351@135614|Xanthomonadales	135614|Xanthomonadales	M	in Yersinia the HmsR protein is an inner membrane protein	hmsR	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_hydro_18,Glyco_tranf_2_3,Polysacc_deac_1
SYD2_k127_5327016_3	278963.ATWD01000002_gene781	1.094e-54	211.0	COG1807@1|root,COG1807@2|Bacteria,3Y3EH@57723|Acidobacteria,2JHRT@204432|Acidobacteriia	204432|Acidobacteriia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SYD2_k127_5327094_7	445972.ANACOL_03673	6.356e-09	57.0	COG4845@1|root,COG4845@2|Bacteria,1V9NV@1239|Firmicutes,24FCQ@186801|Clostridia,3WKDT@541000|Ruminococcaceae	186801|Clostridia	V	Chloramphenicol acetyltransferase	-	-	2.3.1.28	ko:K19271	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CAT
SYD2_k127_5327094_2	263820.PTO0135	1.017e-103	376.0	COG0515@1|root,arCOG03682@2157|Archaea,2XWZP@28890|Euryarchaeota	28890|Euryarchaeota	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NosD,Pkinase
SYD2_k127_5327094_4	1382359.JIAL01000001_gene1619	3.006e-61	237.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,3Y2UJ@57723|Acidobacteria,2JIUE@204432|Acidobacteriia	204432|Acidobacteriia	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,YfiO
SYD2_k127_5327094_0	1122604.JONR01000025_gene4602	3.136e-121	413.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SHX7@1236|Gammaproteobacteria,1X4MN@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SYD2_k127_5327094_5	483219.LILAB_32755	5.681e-35	156.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
SYD2_k127_5327094_1	1122604.JONR01000025_gene4602	7.447e-120	409.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SHX7@1236|Gammaproteobacteria,1X4MN@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SYD2_k127_5327094_8	1123508.JH636450_gene7079	1.61e-08	61.0	2A5R9@1|root,30UG8@2|Bacteria,2J3NV@203682|Planctomycetes	203682|Planctomycetes	S	tRNA_anti-like	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_anti-like
SYD2_k127_5327094_3	28564.XP_002340131.1	3.034e-91	312.0	KOG4155@1|root,KOG4155@2759|Eukaryota,3AG0Y@33154|Opisthokonta,3Q4RG@4751|Fungi,3RN16@4890|Ascomycota,20UKC@147545|Eurotiomycetes,3SE9V@5042|Eurotiales	4751|Fungi	S	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,NACHT,WD40
SYD2_k127_5327094_6	634500.EbC_03460	1.964e-21	100.0	2DXJJ@1|root,3459P@2|Bacteria,1P18T@1224|Proteobacteria,1SRIC@1236|Gammaproteobacteria,3X6H0@551|Erwinia	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3828)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3828
SYD2_k127_5348646_7	240015.ACP_0036	4.927e-16	84.0	COG3525@1|root,COG3525@2|Bacteria,3Y77I@57723|Acidobacteria,2JKDD@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
SYD2_k127_5348646_4	945713.IALB_0983	1.185e-109	366.0	COG4299@1|root,COG4299@2|Bacteria	2|Bacteria	G	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
SYD2_k127_5348646_6	204669.Acid345_2176	9.121e-26	110.0	COG4274@1|root,COG4274@2|Bacteria,3Y8NH@57723|Acidobacteria,2JNFZ@204432|Acidobacteriia	204432|Acidobacteriia	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SYD2_k127_5348646_0	204669.Acid345_3836	1.372e-173	561.0	COG2027@1|root,COG3653@1|root,COG2027@2|Bacteria,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria,2JJ0K@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SYD2_k127_5348646_2	1449126.JQKL01000021_gene73	6.339e-130	431.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,267UW@186813|unclassified Clostridiales	186801|Clostridia	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SYD2_k127_5348646_3	504472.Slin_4173	8.23e-115	384.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,47M3Z@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SYD2_k127_5348646_5	44056.XP_009037845.1	9.403e-48	180.0	2E7M4@1|root,2SUIT@2759|Eukaryota	2759|Eukaryota	S	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_4
SYD2_k127_5348646_1	1382359.JIAL01000001_gene1021	2.227e-173	555.0	COG1574@1|root,COG1574@2|Bacteria,3Y2UF@57723|Acidobacteria,2JIRH@204432|Acidobacteriia	204432|Acidobacteriia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SYD2_k127_5354769_0	1303518.CCALI_01492	3.115e-112	374.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SYD2_k127_5354769_4	99598.Cal7507_4148	1.059e-06	61.0	28I6X@1|root,2Z89S@2|Bacteria,1G0VT@1117|Cyanobacteria,1HJ31@1161|Nostocales	1117|Cyanobacteria	S	Domain of unknown function (DUF4350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
SYD2_k127_5354769_2	1144275.COCOR_05604	2.022e-12	78.0	2EQIM@1|root,33I4N@2|Bacteria,1NJZ4@1224|Proteobacteria,42XX4@68525|delta/epsilon subdivisions,2WST7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SYD2_k127_5354769_3	1121019.AUMN01000004_gene1426	2.925e-08	65.0	COG4223@1|root,COG4223@2|Bacteria,2I390@201174|Actinobacteria,1W9UN@1268|Micrococcaceae	201174|Actinobacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
SYD2_k127_5354769_1	234267.Acid_5396	1.001e-43	164.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SYD2_k127_5394997_2	383372.Rcas_0579	3.057e-19	97.0	COG0768@1|root,COG0768@2|Bacteria,2G7V1@200795|Chloroflexi,374Y3@32061|Chloroflexia	32061|Chloroflexia	M	PFAM penicillin-binding protein transpeptidase	-	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SYD2_k127_5394997_1	2074.JNYD01000004_gene4916	5.197e-35	152.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4DZX9@85010|Pseudonocardiales	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SYD2_k127_5394997_0	1122939.ATUD01000013_gene874	3.638e-49	188.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CQ6E@84995|Rubrobacteria	84995|Rubrobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SYD2_k127_5411044_1	365528.KB891208_gene3103	9.081e-153	501.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4ES2Q@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM 2-oxoglutarate dehydrogenase, E1	kgd	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SYD2_k127_5411044_2	485913.Krac_3207	5.807e-117	386.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,2G6TT@200795|Chloroflexi	200795|Chloroflexi	L	Methylated-DNA- protein -cysteine S-methyltransferase DNA binding	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
SYD2_k127_5411044_0	1254432.SCE1572_35510	1.216e-193	614.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42MDU@68525|delta/epsilon subdivisions,2WM9V@28221|Deltaproteobacteria,2YUA7@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SYD2_k127_5411044_4	1379698.RBG1_1C00001G0519	1.757e-47	183.0	COG0697@1|root,COG0697@2|Bacteria,2NPZZ@2323|unclassified Bacteria	2|Bacteria	EG	EamA-like transporter family	pagO	-	-	ko:K07790	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.7	-	-	EamA
SYD2_k127_5411044_3	1117319.PSPO_14244	8.597e-75	259.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,1RYXR@1236|Gammaproteobacteria,2Q1G4@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	enzyme related to lactoylglutathione lyase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SYD2_k127_5411044_6	1218076.BAYB01000018_gene3431	4.389e-05	46.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,1R6F1@1224|Proteobacteria,2VMW2@28216|Betaproteobacteria,1K3HB@119060|Burkholderiaceae	28216|Betaproteobacteria	P	SMART Rhodanese domain protein	dedA_2	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
SYD2_k127_5411044_5	269799.Gmet_1013	3.651e-09	59.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SYD2_k127_5474869_1	316067.Geob_0841	2.311e-39	151.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,42URG@68525|delta/epsilon subdivisions,2WNDG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mceE	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SYD2_k127_5474869_3	667014.Thein_1029	1.653e-23	116.0	COG0760@1|root,COG0760@2|Bacteria,2GHMC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
SYD2_k127_5474869_0	330214.NIDE3119	2.602e-68	241.0	COG0491@1|root,COG0491@2|Bacteria,3J1C9@40117|Nitrospirae	40117|Nitrospirae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SYD2_k127_5474869_2	278963.ATWD01000001_gene3702	1.374e-37	144.0	COG0005@1|root,COG0005@2|Bacteria,3Y2MA@57723|Acidobacteria,2JI5Q@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SYD2_k127_5499031_0	945713.IALB_2579	3.021e-208	666.0	COG1472@1|root,COG1472@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 3 family	bglX	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0008422,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015926,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SYD2_k127_5499031_1	1198114.AciX9_2444	1.199e-193	629.0	COG0463@1|root,COG1216@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria,3Y932@57723|Acidobacteria,2JNPK@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SYD2_k127_5499031_4	1048983.EL17_19710	1.845e-06	60.0	COG1216@1|root,COG1216@2|Bacteria,4NSTS@976|Bacteroidetes,47YM5@768503|Cytophagia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SYD2_k127_5499031_5	696747.NIES39_R00930	0.0001037	51.0	COG5465@1|root,COG5465@2|Bacteria,1G3IY@1117|Cyanobacteria,1HAA9@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
SYD2_k127_5499031_3	1123261.AXDW01000010_gene358	4.224e-18	96.0	COG5412@1|root,COG5412@2|Bacteria,1N710@1224|Proteobacteria,1S7X2@1236|Gammaproteobacteria,1X9ES@135614|Xanthomonadales	135614|Xanthomonadales	S	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_552640_0	204669.Acid345_4479	2.498e-79	282.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,3Y3X3@57723|Acidobacteria,2JHXN@204432|Acidobacteriia	204432|Acidobacteriia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SYD2_k127_552640_1	483219.LILAB_32760	5.527e-71	249.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2WJ4I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535,ko:K13599	ko00540,ko01100,ko02020,map00540,map01100,map02020	M00060,M00498	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005,ko02022	-	-	-	LpxC
SYD2_k127_5526711_0	1499967.BAYZ01000167_gene6718	7.953e-214	675.0	COG0556@1|root,COG0556@2|Bacteria,2NNPM@2323|unclassified Bacteria	2|Bacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03702,ko:K08999	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SYD2_k127_5526711_1	1519464.HY22_10910	1.147e-161	524.0	COG0277@1|root,COG0277@2|Bacteria,1FDCI@1090|Chlorobi	1090|Chlorobi	C	PFAM FAD linked oxidase domain protein	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SYD2_k127_5526711_3	1128427.KB904821_gene1417	3.868e-07	61.0	COG2319@1|root,COG2319@2|Bacteria,1G208@1117|Cyanobacteria,1HAM3@1150|Oscillatoriales	1117|Cyanobacteria	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5526711_2	292459.STH1950	5.526e-85	287.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SYD2_k127_5532511_1	1033743.CAES01000078_gene3722	2.632e-30	128.0	COG0175@1|root,COG0175@2|Bacteria,1TYGS@1239|Firmicutes,4I7M1@91061|Bacilli,26X16@186822|Paenibacillaceae	91061|Bacilli	EH	Phosphoadenosine phosphosulfate reductase family	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
SYD2_k127_5532511_2	313612.L8106_26832	3.904e-11	65.0	COG1396@1|root,COG1396@2|Bacteria,1GAWA@1117|Cyanobacteria,1HDNN@1150|Oscillatoriales	1117|Cyanobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SYD2_k127_5532511_3	688270.Celal_2809	9.981e-08	64.0	COG2911@1|root,COG2911@2|Bacteria,4NS01@976|Bacteroidetes,1I3QG@117743|Flavobacteriia,1F8HT@104264|Cellulophaga	976|Bacteroidetes	M	InterPro IPR003367	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C
SYD2_k127_5532511_0	278957.ABEA03000097_gene786	3.803e-153	539.0	COG3209@1|root,COG3209@2|Bacteria,46VWR@74201|Verrucomicrobia,3K8JF@414999|Opitutae	414999|Opitutae	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
SYD2_k127_5550092_5	714943.Mucpa_4583	4.452e-21	109.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1IR3V@117747|Sphingobacteriia	976|Bacteroidetes	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
SYD2_k127_5550092_3	338963.Pcar_3086	2.318e-39	157.0	COG2197@1|root,COG2197@2|Bacteria,1PHR7@1224|Proteobacteria,42UJB@68525|delta/epsilon subdivisions,2WQPN@28221|Deltaproteobacteria,43SQ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SYD2_k127_5550092_1	1267533.KB906736_gene1091	5.224e-106	358.0	COG2355@1|root,COG2355@2|Bacteria,3Y39A@57723|Acidobacteria,2JI1H@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SYD2_k127_5550092_2	635013.TherJR_2454	3.623e-86	299.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,260TE@186807|Peptococcaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SYD2_k127_5550092_0	945713.IALB_0156	2.775e-142	464.0	COG4198@1|root,COG4198@2|Bacteria	2|Bacteria	-	-	gdh	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	DUF1015
SYD2_k127_5550092_4	1379698.RBG1_1C00001G1077	4.797e-32	132.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SYD2_k127_5580969_4	234267.Acid_2848	9.027e-65	231.0	COG1044@1|root,COG1044@2|Bacteria,3Y6ZT@57723|Acidobacteria	57723|Acidobacteria	M	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD	-	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
SYD2_k127_5580969_5	748247.AZKH_0086	3.15e-11	68.0	COG0846@1|root,COG0846@2|Bacteria,1PYW1@1224|Proteobacteria,2WE0M@28216|Betaproteobacteria,2KYCP@206389|Rhodocyclales	206389|Rhodocyclales	K	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
SYD2_k127_5580969_0	1382359.JIAL01000001_gene12	3.722e-213	681.0	COG1964@1|root,COG1964@2|Bacteria,3Y2WC@57723|Acidobacteria,2JHTH@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
SYD2_k127_5580969_6	452662.SJA_C2-05610	1.649e-07	61.0	2E6R2@1|root,331B7@2|Bacteria,1MZ2F@1224|Proteobacteria,2TY0W@28211|Alphaproteobacteria,2K31A@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5580969_3	370438.PTH_1132	2.567e-77	273.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,25ZZM@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
SYD2_k127_5580969_2	1121405.dsmv_3401	1.863e-135	455.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2MI8S@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SYD2_k127_5580969_1	204669.Acid345_4296	4.51e-175	565.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria,2JHX1@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SYD2_k127_559093_3	1123242.JH636436_gene744	1.482e-56	202.0	COG2318@1|root,COG2318@2|Bacteria,2IZP2@203682|Planctomycetes	203682|Planctomycetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
SYD2_k127_559093_0	204669.Acid345_1270	3.225e-290	896.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia	204432|Acidobacteriia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
SYD2_k127_559093_2	204669.Acid345_1271	5.327e-161	523.0	COG1233@1|root,COG1233@2|Bacteria,3Y3I8@57723|Acidobacteria,2JI78@204432|Acidobacteriia	204432|Acidobacteriia	C	TIGRFAM phytoene desaturase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SYD2_k127_559093_1	575540.Isop_3575	7.155e-208	663.0	COG0531@1|root,COG0531@2|Bacteria,2IXT5@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SYD2_k127_559093_4	247490.KSU1_D0145	1.854e-21	106.0	COG0589@1|root,COG0589@2|Bacteria,2J0XB@203682|Planctomycetes	203682|Planctomycetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SYD2_k127_559093_5	338966.Ppro_0436	5.719e-09	67.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria,43UR0@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Universal stress protein	usp-2	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
SYD2_k127_5607735_1	1242864.D187_006633	8.85e-53	201.0	COG2333@1|root,COG4733@1|root,COG4932@1|root,COG2333@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	3.2.1.4	ko:K01179,ko:K02238,ko:K20276	ko00500,ko01100,ko02024,map00500,map01100,map02024	M00429	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.11.1,3.A.11.2	GH5,GH9	-	Lactamase_B
SYD2_k127_5607735_3	1267534.KB906754_gene3732	1.599e-38	149.0	2DTV5@1|root,33MT0@2|Bacteria,3Y5UW@57723|Acidobacteria,2JNBS@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5607735_0	661478.OP10G_1838	1.103e-147	494.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SYD2_k127_5607735_2	1121931.AUHG01000010_gene708	1.396e-41	159.0	COG4845@1|root,COG4845@2|Bacteria,4NPDG@976|Bacteroidetes,1I20U@117743|Flavobacteriia	976|Bacteroidetes	V	Chloramphenicol acetyltransferase	cat	-	2.3.1.28	ko:K19271	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CAT
SYD2_k127_5614124_0	263820.PTO0135	2.031e-86	327.0	COG0515@1|root,arCOG03682@2157|Archaea,2XWZP@28890|Euryarchaeota	28890|Euryarchaeota	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NosD,Pkinase
SYD2_k127_5614124_3	1280666.ATVS01000005_gene2312	2.427e-38	168.0	COG4166@1|root,COG4166@2|Bacteria,1VRU1@1239|Firmicutes,255ES@186801|Clostridia,4BXT6@830|Butyrivibrio	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SYD2_k127_5614124_1	316274.Haur_3812	1.575e-64	238.0	COG0793@1|root,COG0793@2|Bacteria,2GAAX@200795|Chloroflexi,374TM@32061|Chloroflexia	32061|Chloroflexia	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_S41,Tricorn_C1
SYD2_k127_5614124_2	330214.NIDE2504	4.289e-51	183.0	COG4679@1|root,COG4679@2|Bacteria	2|Bacteria	K	PFAM Phage derived protein Gp49-like (DUF891)	-	GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0065007,GO:0070482,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	-	-	-	-	-	-	-	-	-	-	Gp49
SYD2_k127_5614124_4	330214.NIDE2505	4.692e-33	134.0	COG1396@1|root,COG1396@2|Bacteria,3J1D7@40117|Nitrospirae	40117|Nitrospirae	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5614459_16	1267533.KB906736_gene1412	1.816e-37	156.0	COG4424@1|root,COG4424@2|Bacteria	2|Bacteria	S	carbohydrate metabolic process	nodH	-	-	-	-	-	-	-	-	-	-	-	Asp_Arg_Hydrox,SEC-C,Sulfotransfer_1,Sulfotransfer_3
SYD2_k127_5614459_3	234267.Acid_7636	4.154e-204	664.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SYD2_k127_5614459_12	1242864.D187_001666	7.854e-51	193.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
SYD2_k127_5614459_15	1131269.AQVV01000001_gene1432	5.476e-38	150.0	COG1573@1|root,COG1573@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	ung2	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SYD2_k127_5614459_18	411154.GFO_0980	3.145e-26	113.0	COG1917@1|root,COG1917@2|Bacteria,4P2XE@976|Bacteroidetes,1IAY3@117743|Flavobacteriia	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5614459_19	1172180.KB911801_gene7856	0.0006535	52.0	COG1807@1|root,COG1807@2|Bacteria,2GJPU@201174|Actinobacteria	201174|Actinobacteria	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SYD2_k127_5614459_8	204669.Acid345_2346	6.761e-70	250.0	COG1560@1|root,COG1560@2|Bacteria,3Y2RW@57723|Acidobacteria,2JIMS@204432|Acidobacteriia	204432|Acidobacteriia	M	lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SYD2_k127_5614459_13	472759.Nhal_2071	1.456e-43	169.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,1SEZZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
SYD2_k127_5614459_6	350688.Clos_2654	3.284e-106	357.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia,36EEA@31979|Clostridiaceae	186801|Clostridia	E	Cleaves the N-terminal amino acid of tripeptides	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SYD2_k127_5614459_14	404589.Anae109_2888	7.73e-41	156.0	COG0346@1|root,COG0346@2|Bacteria,1RJR7@1224|Proteobacteria,43844@68525|delta/epsilon subdivisions,2X3E1@28221|Deltaproteobacteria,2YVN0@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SYD2_k127_5614459_11	330214.NIDE0301	8.623e-53	190.0	COG0663@1|root,COG0663@2|Bacteria,3J121@40117|Nitrospirae	40117|Nitrospirae	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SYD2_k127_5614459_0	234267.Acid_2399	1.735e-272	862.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,3Y343@57723|Acidobacteria	57723|Acidobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SYD2_k127_5614459_7	639030.JHVA01000001_gene3564	8.566e-89	306.0	COG0758@1|root,COG0758@2|Bacteria,3Y42M@57723|Acidobacteria,2JI6N@204432|Acidobacteriia	204432|Acidobacteriia	LU	DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SYD2_k127_5614459_1	1254432.SCE1572_07650	3.402e-221	699.0	COG1024@1|root,COG1024@2|Bacteria,1N817@1224|Proteobacteria,4388N@68525|delta/epsilon subdivisions,2XA2D@28221|Deltaproteobacteria,2YW7N@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.1.2.44	ko:K15513	ko00362,map00362	-	R09556	RC03426	ko00000,ko00001,ko01000	-	-	-	ECH_1
SYD2_k127_5614459_2	391625.PPSIR1_36257	2.326e-213	672.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,437U1@68525|delta/epsilon subdivisions,2X33K@28221|Deltaproteobacteria,2YU2K@29|Myxococcales	28221|Deltaproteobacteria	S	benzoyl-CoA oxygenase	-	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
SYD2_k127_5614459_17	1379698.RBG1_1C00001G0893	2.415e-33	139.0	COG1309@1|root,COG1309@2|Bacteria,2NS0M@2323|unclassified Bacteria	2|Bacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
SYD2_k127_5614459_5	1379698.RBG1_1C00001G0806	8.202e-113	370.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SYD2_k127_5614459_10	1120985.AUMI01000021_gene2825	2.097e-62	224.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4H931@909932|Negativicutes	909932|Negativicutes	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SYD2_k127_5614459_9	1382306.JNIM01000001_gene3716	5.246e-64	228.0	COG1028@1|root,COG1028@2|Bacteria,2G8CF@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SYD2_k127_5614459_4	1122216.AUHW01000012_gene1521	1.51e-169	549.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4H32N@909932|Negativicutes	909932|Negativicutes	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA-synt_2d,tRNA_anti-codon
SYD2_k127_5614822_2	1198114.AciX9_2268	6.599e-96	344.0	COG3292@1|root,COG4447@1|root,COG3292@2|Bacteria,COG4447@2|Bacteria,3Y3Y6@57723|Acidobacteria,2JI5Y@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
SYD2_k127_5614822_4	204669.Acid345_3272	6.667e-18	99.0	COG2885@1|root,COG2885@2|Bacteria,3Y310@57723|Acidobacteria,2JI18@204432|Acidobacteriia	204432|Acidobacteriia	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SYD2_k127_5614822_0	204669.Acid345_4115	3.073e-184	585.0	COG0334@1|root,COG0334@2|Bacteria,3Y3B4@57723|Acidobacteria,2JI4Q@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SYD2_k127_5614822_5	209285.XP_006693273.1	5.707e-05	55.0	COG0639@1|root,KOG0376@2759|Eukaryota,38E0Z@33154|Opisthokonta,3NU3F@4751|Fungi,3QMVT@4890|Ascomycota,2151F@147550|Sordariomycetes,3U69C@5139|Sordariales,3HAW4@35718|Chaetomiaceae	4751|Fungi	T	Serine threonine-protein phosphatase	PPT1	GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0023052,GO:0036211,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564	3.1.3.16	ko:K04460	ko04010,map04010	-	-	-	ko00000,ko00001,ko01000,ko01009	-	-	-	Metallophos,PPP5,TPR_1,TPR_11,TPR_8
SYD2_k127_5614822_6	765911.Thivi_0139	0.0001317	54.0	COG0457@1|root,COG0457@2|Bacteria,1R50I@1224|Proteobacteria,1S4B5@1236|Gammaproteobacteria,1X26Z@135613|Chromatiales	135613|Chromatiales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5614822_3	1118054.CAGW01000024_gene422	2.677e-51	191.0	COG2234@1|root,COG2234@2|Bacteria,1V0YM@1239|Firmicutes,4HB51@91061|Bacilli,271K2@186822|Paenibacillaceae	91061|Bacilli	S	Transferrin receptor-like dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28,TFR_dimer
SYD2_k127_5614822_1	204669.Acid345_2466	3.925e-129	426.0	COG2234@1|root,COG2234@2|Bacteria,3Y33F@57723|Acidobacteria,2JI7G@204432|Acidobacteriia	204432|Acidobacteriia	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
SYD2_k127_5614822_7	485913.Krac_12159	0.0003512	47.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FHA,zinc_ribbon_2
SYD2_k127_5630850_0	1267533.KB906739_gene2555	5.923e-255	805.0	COG1185@1|root,COG1185@2|Bacteria,3Y2UG@57723|Acidobacteria,2JI5F@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SYD2_k127_5630850_14	1051632.TPY_1695	1.471e-30	122.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,3WCM8@538999|Clostridiales incertae sedis	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SYD2_k127_5630850_11	582515.KR51_00032260	7.009e-69	249.0	COG1252@1|root,COG1252@2|Bacteria,1G26A@1117|Cyanobacteria	1117|Cyanobacteria	C	NADH dehydrogenase, FAD-containing subunit	ndbB	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SYD2_k127_5630850_12	28072.Nos7524_4754	5.432e-49	179.0	COG0614@1|root,COG0614@2|Bacteria,1G71C@1117|Cyanobacteria,1HP4K@1161|Nostocales	1117|Cyanobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
SYD2_k127_5630850_2	1254432.SCE1572_31205	2.708e-177	568.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2YUKP@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SYD2_k127_5630850_13	886293.Sinac_0726	4.188e-34	146.0	COG0613@1|root,COG0613@2|Bacteria,2J1VB@203682|Planctomycetes	203682|Planctomycetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5630850_19	204669.Acid345_1460	1.386e-25	121.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FecR,LysM,fn3
SYD2_k127_5630850_3	401053.AciPR4_0872	2.418e-172	545.0	COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria,2JHQ2@204432|Acidobacteriia	204432|Acidobacteriia	D	cell shape determining protein MreB	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SYD2_k127_5630850_17	589865.DaAHT2_1934	3.989e-28	125.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2MJMG@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SYD2_k127_5630850_5	204669.Acid345_1465	2.987e-114	392.0	COG0768@1|root,COG0768@2|Bacteria,3Y3MX@57723|Acidobacteria,2JHRD@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein, dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SYD2_k127_5630850_10	1198114.AciX9_0894	4.442e-71	254.0	COG0772@1|root,COG0772@2|Bacteria,3Y3DZ@57723|Acidobacteria,2JINX@204432|Acidobacteriia	204432|Acidobacteriia	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SYD2_k127_5630850_18	1353529.M899_2646	2.341e-26	126.0	COG3210@1|root,COG3210@2|Bacteria,1NED3@1224|Proteobacteria,42WDX@68525|delta/epsilon subdivisions,2MTVC@213481|Bdellovibrionales,2WRDH@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	cell wall surface anchor family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
SYD2_k127_5630850_7	335543.Sfum_1625	4.683e-86	308.0	COG5295@1|root,COG5295@2|Bacteria,1NI1M@1224|Proteobacteria,42ZTF@68525|delta/epsilon subdivisions,2WV01@28221|Deltaproteobacteria	28221|Deltaproteobacteria	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
SYD2_k127_5630850_1	335543.Sfum_1617	7.148e-193	619.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
SYD2_k127_5630850_8	335543.Sfum_1616	3.881e-82	295.0	COG0457@1|root,COG0457@2|Bacteria,1PFBA@1224|Proteobacteria,43755@68525|delta/epsilon subdivisions,2WQN6@28221|Deltaproteobacteria,2MSBR@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
SYD2_k127_5630850_16	56780.SYN_01127	6.317e-29	137.0	COG1345@1|root,COG1957@1|root,COG3204@1|root,COG1345@2|Bacteria,COG1957@2|Bacteria,COG3204@2|Bacteria,1QVAA@1224|Proteobacteria,43BPG@68525|delta/epsilon subdivisions,2X70T@28221|Deltaproteobacteria,2MR3K@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5630850_9	1519464.HY22_05890	2.652e-72	280.0	COG1864@1|root,COG1864@2|Bacteria,1FFIK@1090|Chlorobi	1090|Chlorobi	F	DNA/RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
SYD2_k127_5630850_6	234267.Acid_5965	8.316e-104	382.0	COG2374@1|root,COG3386@1|root,COG2374@2|Bacteria,COG3386@2|Bacteria,3Y6HZ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Endonuclease Exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	DUF1573,Exo_endo_phos,LTD
SYD2_k127_5630850_4	240015.ACP_0332	3.158e-125	430.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
SYD2_k127_5630850_15	1340493.JNIF01000003_gene3684	1.809e-30	137.0	COG1530@1|root,COG1530@2|Bacteria,3Y40K@57723|Acidobacteria	57723|Acidobacteria	J	Ribonuclease, Rne Rng family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
SYD2_k127_5637569_3	794846.AJQU01000057_gene293	8.014e-40	151.0	COG1653@1|root,COG1653@2|Bacteria,1MUNZ@1224|Proteobacteria,2U2Z9@28211|Alphaproteobacteria,4BCTU@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
SYD2_k127_5637569_2	1499967.BAYZ01000009_gene5384	3.515e-81	280.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
SYD2_k127_5637569_1	1499967.BAYZ01000009_gene5385	2.966e-98	328.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SYD2_k127_5637569_0	368408.Tpen_1165	1.525e-107	360.0	COG3839@1|root,arCOG00175@2157|Archaea,2XPUC@28889|Crenarchaeota	28889|Crenarchaeota	G	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SYD2_k127_5637569_4	688269.Theth_1106	3.241e-05	48.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	iolI	-	5.3.99.11	ko:K06606	ko00562,ko01120,map00562,map01120	-	R09952	RC01513	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SYD2_k127_5642803_5	70448.A0A090M8B7	3.666e-05	47.0	COG0666@1|root,KOG4177@2759|Eukaryota	2759|Eukaryota	I	spectrin binding	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Ank_5,U-box
SYD2_k127_5642803_1	886293.Sinac_3494	1.679e-118	390.0	COG0500@1|root,COG4742@1|root,COG2226@2|Bacteria,COG4742@2|Bacteria,2IXEP@203682|Planctomycetes	203682|Planctomycetes	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
SYD2_k127_5642803_3	316067.Geob_1840	2.517e-81	278.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,43BI9@68525|delta/epsilon subdivisions,2X6WN@28221|Deltaproteobacteria,43U6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SYD2_k127_5642803_2	485913.Krac_11550	2.502e-91	305.0	COG1814@1|root,COG1814@2|Bacteria,2G7AE@200795|Chloroflexi	200795|Chloroflexi	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SYD2_k127_5642803_4	644282.Deba_1971	3.337e-27	112.0	COG2119@1|root,COG2119@2|Bacteria,1NDE6@1224|Proteobacteria,42W66@68525|delta/epsilon subdivisions,2WS4K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
SYD2_k127_5642803_0	886293.Sinac_1156	6.645e-250	808.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
SYD2_k127_5659711_8	324602.Caur_2655	2.037e-32	139.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,2G7J8@200795|Chloroflexi,374RZ@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
SYD2_k127_5659711_5	46234.ANA_C10101	1.961e-57	220.0	COG0457@1|root,COG0457@2|Bacteria,1G36K@1117|Cyanobacteria,1HQDG@1161|Nostocales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,TIR_2,TPR_1,TPR_11,TPR_2,TPR_4,TPR_8,Trypsin_2
SYD2_k127_5659711_11	1132855.KB913035_gene57	3.513e-21	102.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2VU93@28216|Betaproteobacteria,2KMY4@206350|Nitrosomonadales	206350|Nitrosomonadales	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SYD2_k127_5659711_7	1382359.JIAL01000001_gene880	5.597e-46	170.0	COG0782@1|root,COG0782@2|Bacteria,3Y49X@57723|Acidobacteria,2JJ1A@204432|Acidobacteriia	204432|Acidobacteriia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SYD2_k127_5659711_14	1297865.APJD01000003_gene6125	0.0006794	49.0	2E9MA@1|root,333TZ@2|Bacteria,1NBIS@1224|Proteobacteria,2UI51@28211|Alphaproteobacteria,3JZD4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5659711_6	234267.Acid_6711	4.815e-50	186.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf,DUF4833
SYD2_k127_5659711_13	278963.ATWD01000001_gene3375	4.314e-05	50.0	2EN0M@1|root,33FNU@2|Bacteria,3Y60X@57723|Acidobacteria,2JJZX@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5659711_1	1184267.A11Q_2562	6.617e-157	510.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2MTQX@213481|Bdellovibrionales,2WIN7@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SYD2_k127_5659711_10	204669.Acid345_0154	2.56e-28	122.0	COG4770@1|root,COG4770@2|Bacteria,3Y5QJ@57723|Acidobacteria,2JN6E@204432|Acidobacteriia	204432|Acidobacteriia	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
SYD2_k127_5659711_9	1123376.AUIU01000011_gene1137	3.031e-32	135.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	gph1	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD,HAD_2,Hydrolase_like
SYD2_k127_5659711_12	1379698.RBG1_1C00001G1798	2.668e-19	93.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5659711_0	401053.AciPR4_0620	1.949e-166	545.0	COG0323@1|root,COG0323@2|Bacteria,3Y2T3@57723|Acidobacteria,2JI29@204432|Acidobacteriia	204432|Acidobacteriia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
SYD2_k127_5659711_3	204669.Acid345_2181	1.765e-88	313.0	COG4365@1|root,COG4365@2|Bacteria,3Y4D6@57723|Acidobacteria,2JKER@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
SYD2_k127_5659711_4	1125863.JAFN01000001_gene1971	8.749e-77	268.0	COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria	1224|Proteobacteria	EM	Belongs to the DapA family	yagE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575	4.1.2.28,4.3.3.7	ko:K01714,ko:K22397	ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R01782,R10147	RC00307,RC00572,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SYD2_k127_5659711_2	204669.Acid345_4746	5.107e-92	312.0	COG0413@1|root,COG0413@2|Bacteria,3Y3GX@57723|Acidobacteria,2JI6Y@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SYD2_k127_5693312_4	163908.KB235896_gene741	8.933e-29	122.0	COG1943@1|root,COG1943@2|Bacteria,1G6SS@1117|Cyanobacteria,1HNZ8@1161|Nostocales	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SYD2_k127_5693312_1	639282.DEFDS_0485	1.061e-173	554.0	COG0112@1|root,COG0112@2|Bacteria,2GERI@200930|Deferribacteres	200930|Deferribacteres	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SYD2_k127_5693312_0	290397.Adeh_3947	4.516e-213	677.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,2YZII@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SYD2_k127_5693312_2	247490.KSU1_C1161	2.605e-76	274.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	yidC	-	-	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,DUF4124,PDZ_2,Peptidase_C11,SLH,TPM_phosphatase,TPR_11,Trypsin_2,YidC_periplas
SYD2_k127_5693312_3	983917.RGE_30750	8.893e-55	204.0	COG0412@1|root,COG0412@2|Bacteria,1Q876@1224|Proteobacteria,2WC50@28216|Betaproteobacteria,1KP8A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SYD2_k127_5700729_8	1379698.RBG1_1C00001G0328	3.444e-50	183.0	2C7E0@1|root,330TX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5700729_4	309801.trd_A0816	1.266e-84	299.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	189775|Thermomicrobia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SYD2_k127_5700729_5	1380390.JIAT01000009_gene362	5.227e-71	252.0	COG1817@1|root,COG1817@2|Bacteria,2HQP4@201174|Actinobacteria,4CSA7@84995|Rubrobacteria	2|Bacteria	S	Protein of unknown function (DUF354)	-	-	-	ko:K09726	-	-	-	-	ko00000	-	-	-	DUF354
SYD2_k127_5700729_15	211165.AJLN01000145_gene1206	3.351e-09	58.0	2CCSR@1|root,32RWC@2|Bacteria,1G749@1117|Cyanobacteria,1JIYR@1189|Stigonemataceae	1117|Cyanobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SYD2_k127_5700729_12	1173023.KE650771_gene4164	3.779e-21	95.0	2CCSR@1|root,32RWC@2|Bacteria,1G749@1117|Cyanobacteria,1JIYR@1189|Stigonemataceae	1117|Cyanobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SYD2_k127_5700729_3	1288963.ADIS_4011	2.889e-89	310.0	COG1331@1|root,COG1331@2|Bacteria,4NIPN@976|Bacteroidetes	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
SYD2_k127_5700729_0	1128427.KB904821_gene205	3.459e-185	598.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SYD2_k127_5700729_9	765420.OSCT_2410	2.079e-46	169.0	COG0614@1|root,COG0614@2|Bacteria,2G9KR@200795|Chloroflexi,377DT@32061|Chloroflexia	32061|Chloroflexia	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
SYD2_k127_5700729_2	269799.Gmet_2892	6.456e-109	363.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42MCE@68525|delta/epsilon subdivisions,2WIYP@28221|Deltaproteobacteria,43U7K@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
SYD2_k127_5700729_1	63577.G9NQK4	5.712e-132	428.0	COG1087@1|root,KOG1371@2759|Eukaryota,39KCQ@33154|Opisthokonta,3PBHS@4751|Fungi,3RN10@4890|Ascomycota	4751|Fungi	M	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
SYD2_k127_5700729_6	517418.Ctha_2714	4.028e-61	221.0	COG0500@1|root,COG2226@2|Bacteria,1FFN6@1090|Chlorobi	1090|Chlorobi	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SYD2_k127_5700729_14	861299.J421_0665	6.812e-11	68.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11	ko:K03636,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiS
SYD2_k127_5700729_11	1123023.JIAI01000003_gene2566	3.04e-21	104.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SYD2_k127_5700729_7	1191523.MROS_1301	2.864e-60	213.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SYD2_k127_5700729_10	113395.AXAI01000032_gene685	1.157e-41	162.0	COG0300@1|root,COG0300@2|Bacteria,1R3VU@1224|Proteobacteria,2TWRJ@28211|Alphaproteobacteria,3K6MX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc,adh_short,adh_short_C2
SYD2_k127_5710989_3	1122176.KB903565_gene3401	6.611e-05	54.0	COG3591@1|root,COG4935@1|root,COG3591@2|Bacteria,COG4935@2|Bacteria,4NG2K@976|Bacteroidetes,1IY1U@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the peptidase S1B family	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Trypsin_2
SYD2_k127_5710989_1	1345023.M467_13865	1.761e-56	205.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,3WFAW@539002|Bacillales incertae sedis	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SYD2_k127_5710989_0	926566.Terro_2757	1.526e-141	471.0	COG1132@1|root,COG1132@2|Bacteria,3Y2Y9@57723|Acidobacteria,2JI79@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
SYD2_k127_5710989_2	686340.Metal_0128	8.111e-08	53.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,1XDJD@135618|Methylococcales	135618|Methylococcales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SYD2_k127_5751642_1	1340493.JNIF01000003_gene1663	9.95e-44	182.0	28MCK@1|root,2ZAQP@2|Bacteria,3Y41I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5751642_0	204669.Acid345_3828	1.932e-89	306.0	COG3303@1|root,COG3303@2|Bacteria,3Y999@57723|Acidobacteria,2JP5G@204432|Acidobacteriia	204432|Acidobacteriia	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
SYD2_k127_5751642_2	204669.Acid345_1498	1.708e-43	168.0	COG0664@1|root,COG0664@2|Bacteria,3Y4IX@57723|Acidobacteria,2JJ9U@204432|Acidobacteriia	204432|Acidobacteriia	K	cyclic nucleotide-binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SYD2_k127_5790836_0	861299.J421_2314	1.338e-102	343.0	COG0477@1|root,COG2814@2|Bacteria,1ZT84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SYD2_k127_5790836_7	926562.Oweho_2142	1.654e-11	68.0	COG1225@1|root,COG1225@2|Bacteria,4NGWI@976|Bacteroidetes,1IJ05@117743|Flavobacteriia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SYD2_k127_5790836_6	903818.KI912268_gene1907	1.782e-20	99.0	COG2365@1|root,COG2365@2|Bacteria,3Y8BW@57723|Acidobacteria	57723|Acidobacteria	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase2
SYD2_k127_5790836_4	1297742.A176_03861	1.141e-35	144.0	COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,42RQP@68525|delta/epsilon subdivisions,2WNQ7@28221|Deltaproteobacteria,2YVU0@29|Myxococcales	28221|Deltaproteobacteria	T	Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
SYD2_k127_5790836_5	1121904.ARBP01000002_gene7201	4.797e-30	126.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,47R7I@768503|Cytophagia	976|Bacteroidetes	T	PFAM Phosphoglycerate mutase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SYD2_k127_5790836_1	485913.Krac_9228	2.154e-93	313.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	ko:K00560,ko:K00943,ko:K01585	ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523	M00053,M00133	R00566,R02094,R02098,R02101	RC00002,RC00219,RC00299,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
SYD2_k127_5790836_2	485913.Krac_9227	3.122e-69	245.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.9,4.1.1.19	ko:K00943,ko:K01585	ko00240,ko00330,ko01100,map00240,map00330,map01100	M00053,M00133	R00566,R02094,R02098	RC00002,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
SYD2_k127_5790836_3	317936.Nos7107_4668	6.955e-51	192.0	COG0248@1|root,COG0248@2|Bacteria,1FZZC@1117|Cyanobacteria,1HIZ5@1161|Nostocales	1117|Cyanobacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
SYD2_k127_5807876_7	765869.BDW_12775	5.861e-58	213.0	COG0642@1|root,COG0642@2|Bacteria,1QY2Q@1224|Proteobacteria,43C9Z@68525|delta/epsilon subdivisions,2MUTA@213481|Bdellovibrionales,2X7KF@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SYD2_k127_5807876_6	264462.Bd3451	1.819e-64	231.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,43AK3@68525|delta/epsilon subdivisions,2MT4V@213481|Bdellovibrionales,2WVKV@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SYD2_k127_5807876_2	765869.BDW_12785	9.882e-116	384.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2MSZ3@213481|Bdellovibrionales,2WJZK@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
SYD2_k127_5807876_0	765869.BDW_12790	1.066e-177	572.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,42M87@68525|delta/epsilon subdivisions,2MSM3@213481|Bdellovibrionales,2WMB0@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SYD2_k127_5807876_5	264462.Bd3455	3.441e-74	265.0	COG1232@1|root,COG1232@2|Bacteria,1R0KQ@1224|Proteobacteria,42NBG@68525|delta/epsilon subdivisions,2MTXP@213481|Bdellovibrionales,2WKMN@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemY	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SYD2_k127_5807876_11	926566.Terro_3228	1.929e-19	100.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SYD2_k127_5807876_1	240015.ACP_3297	4.332e-175	565.0	COG0138@1|root,COG0138@2|Bacteria,3Y2QI@57723|Acidobacteria,2JHSU@204432|Acidobacteriia	204432|Acidobacteriia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SYD2_k127_5807876_8	443143.GM18_2404	1.058e-22	102.0	COG2250@1|root,COG2250@2|Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
SYD2_k127_5807876_10	340177.Cag_1881	4.21e-20	95.0	2DZ43@1|root,34CCJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5807876_9	1185652.USDA257_c49320	4.913e-22	100.0	COG3755@1|root,COG3755@2|Bacteria,1N8EC@1224|Proteobacteria,2UFJC@28211|Alphaproteobacteria,4BGN7@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	LprI
SYD2_k127_5807876_3	1382359.JIAL01000001_gene1578	6.438e-93	311.0	COG0623@1|root,COG0623@2|Bacteria,3Y3EN@57723|Acidobacteria,2JHZZ@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SYD2_k127_5807876_4	266117.Rxyl_2215	4.722e-81	276.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4CQ3Q@84995|Rubrobacteria	84995|Rubrobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SYD2_k127_5822232_12	1123073.KB899242_gene1567	7.29e-24	102.0	2DBJC@1|root,2Z9K5@2|Bacteria,1NQYW@1224|Proteobacteria	1224|Proteobacteria	G	Glycosyl hydrolase family 47	-	-	3.2.1.113	ko:K01230	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00073,M00074	R05982,R06722	-	ko00000,ko00001,ko00002,ko01000,ko04131	-	GH47	-	Glyco_hydro_47
SYD2_k127_5822232_11	1250005.PHEL85_1235	8.161e-38	148.0	COG3871@1|root,COG3871@2|Bacteria,4PH8Y@976|Bacteroidetes,1IMDQ@117743|Flavobacteriia,3VWHM@52959|Polaribacter	976|Bacteroidetes	S	Pyridoxamine 5'-phosphate oxidase like	-	-	-	-	-	-	-	-	-	-	-	-	Pyrid_ox_like
SYD2_k127_5822232_9	1408418.JNJH01000030_gene2376	5.891e-47	193.0	COG3712@1|root,COG3712@2|Bacteria,1N941@1224|Proteobacteria,2U29D@28211|Alphaproteobacteria,2JPIM@204441|Rhodospirillales	204441|Rhodospirillales	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5822232_6	519989.ECTPHS_02044	4.877e-76	261.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,1WWMM@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SYD2_k127_5822232_2	682795.AciX8_1960	2.022e-161	521.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria,2JIZJ@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SYD2_k127_5822232_10	797299.HALLA_01155	4.729e-39	150.0	COG2258@1|root,arCOG11383@2157|Archaea,2XXK8@28890|Euryarchaeota,23VKF@183963|Halobacteria	183963|Halobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SYD2_k127_5822232_3	553973.CLOHYLEM_07748	1.348e-108	362.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,21XEQ@1506553|Lachnoclostridium	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SYD2_k127_5822232_8	240015.ACP_2906	1.562e-52	191.0	COG0742@1|root,COG0742@2|Bacteria,3Y4K0@57723|Acidobacteria,2JJDW@204432|Acidobacteriia	204432|Acidobacteriia	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
SYD2_k127_5822232_7	379066.GAU_3598	7.597e-76	267.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
SYD2_k127_5822232_1	1278073.MYSTI_04523	1.003e-171	565.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2WKBA@28221|Deltaproteobacteria,2YXV4@29|Myxococcales	28221|Deltaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SYD2_k127_5822232_13	1031288.AXAA01000006_gene1147	1.38e-23	107.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,36IUF@31979|Clostridiaceae	186801|Clostridia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SYD2_k127_5822232_4	671143.DAMO_1556	4.996e-94	329.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2NNR2@2323|unclassified Bacteria	2|Bacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SYD2_k127_5822232_0	234267.Acid_1531	1.571e-186	600.0	COG0728@1|root,COG0728@2|Bacteria,3Y6N1@57723|Acidobacteria	57723|Acidobacteria	S	MviN-like protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SYD2_k127_5822232_5	204669.Acid345_1588	1.054e-84	287.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria,2JKV3@204432|Acidobacteriia	204432|Acidobacteriia	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SYD2_k127_5825363_7	1547437.LL06_08345	2.226e-17	86.0	COG1917@1|root,COG1917@2|Bacteria,1N73J@1224|Proteobacteria	1224|Proteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5825363_6	240292.Ava_2652	2.638e-30	128.0	COG1572@1|root,COG1572@2|Bacteria,1GBQN@1117|Cyanobacteria,1HN4C@1161|Nostocales	1117|Cyanobacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5825363_2	1128421.JAGA01000003_gene2890	1.169e-104	355.0	COG2239@1|root,COG2239@2|Bacteria,2NP6V@2323|unclassified Bacteria	2|Bacteria	P	Acts as a magnesium transporter	mgtE	-	3.6.1.1	ko:K04767,ko:K06213,ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000,ko02000	1.A.26.1	-	-	CBS,DHH,DHHA2,DRTGG,MgtE,MgtE_N,PRC
SYD2_k127_5825363_5	1501230.ET33_19280	1.242e-31	132.0	COG3797@1|root,COG3797@2|Bacteria,1VJ1T@1239|Firmicutes,4HQ2E@91061|Bacilli,274WH@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SYD2_k127_5825363_1	177437.HRM2_00430	0.0	1037.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2MHN2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
SYD2_k127_5825363_9	383372.Rcas_4058	0.0004714	52.0	COG4260@1|root,COG4260@2|Bacteria,2G6J2@200795|Chloroflexi	200795|Chloroflexi	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17,zinc_ribbon_2
SYD2_k127_5825363_4	1230343.CANP01000005_gene502	1.439e-39	159.0	28JIP@1|root,2Z82C@2|Bacteria,1R5N9@1224|Proteobacteria,1RY8I@1236|Gammaproteobacteria,1JGK3@118969|Legionellales	118969|Legionellales	S	S1/P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease
SYD2_k127_5825363_3	330214.NIDE3250	1.499e-41	169.0	COG0845@1|root,COG0845@2|Bacteria,3J15V@40117|Nitrospirae	2|Bacteria	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	cusB	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
SYD2_k127_5825363_8	1207055.C100_23115	1.678e-06	61.0	COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,2TTFK@28211|Alphaproteobacteria,2K10B@204457|Sphingomonadales	204457|Sphingomonadales	MU	outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SYD2_k127_5825363_0	316067.Geob_2478	0.0	1171.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
SYD2_k127_5847572_0	344747.PM8797T_07137	6.187e-244	777.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,2IXF2@203682|Planctomycetes	203682|Planctomycetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1343
SYD2_k127_5862338_11	234267.Acid_5547	4.213e-55	206.0	COG0392@1|root,COG0392@2|Bacteria,3Y7S6@57723|Acidobacteria	57723|Acidobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SYD2_k127_5862338_16	472759.Nhal_2508	6.755e-08	63.0	COG1073@1|root,COG1073@2|Bacteria,1RFAF@1224|Proteobacteria,1S2YT@1236|Gammaproteobacteria,1X2AF@135613|Chromatiales	135613|Chromatiales	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SYD2_k127_5862338_6	42256.RradSPS_2906	5.721e-123	413.0	COG2898@1|root,COG2898@2|Bacteria,2I2ZR@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	lysX	-	2.3.2.3,6.1.1.6	ko:K04567,ko:K14205	ko00970,ko01503,ko02020,ko05150,map00970,map01503,map02020,map05150	M00359,M00360,M00726	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko01504,ko03016	2.A.1.3.37	-	-	DUF2156,tRNA-synt_2_TM
SYD2_k127_5862338_17	1396141.BATP01000019_gene1705	6.957e-08	63.0	COG2898@1|root,COG2898@2|Bacteria,46ZGD@74201|Verrucomicrobia,2IUPX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Uncharacterised conserved protein (DUF2156)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2156,VirJ
SYD2_k127_5862338_2	1340493.JNIF01000003_gene3991	4.129e-194	625.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	msbA	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SYD2_k127_5862338_1	869210.Marky_1642	1.404e-218	686.0	COG3033@1|root,COG3033@2|Bacteria,1WM62@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SYD2_k127_5862338_3	204669.Acid345_2712	3.018e-162	526.0	COG3005@1|root,COG3005@2|Bacteria,3Y3MU@57723|Acidobacteria,2JJ6B@204432|Acidobacteriia	57723|Acidobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
SYD2_k127_5862338_0	502025.Hoch_4458	1.594e-227	721.0	COG0517@1|root,COG2170@1|root,COG0517@2|Bacteria,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,43BYB@68525|delta/epsilon subdivisions,2X798@28221|Deltaproteobacteria,2YX02@29|Myxococcales	28221|Deltaproteobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
SYD2_k127_5862338_4	269799.Gmet_0555	1.474e-137	452.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SYD2_k127_5862338_8	1385511.N783_07705	1.455e-95	325.0	COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5002@2|Bacteria,1VUBP@1239|Firmicutes,4HUPW@91061|Bacilli	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,HATPase_c,HisKA,MASE3,MHYT,PAS,PAS_3,PAS_4,PAS_9
SYD2_k127_5862338_5	1122604.JONR01000045_gene2500	2.054e-130	427.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,1SZK5@1236|Gammaproteobacteria,1XCD9@135614|Xanthomonadales	135614|Xanthomonadales	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N
SYD2_k127_5862338_7	420324.KI911965_gene544	1.026e-111	366.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria,1JUHK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	C-terminal domain of 1-Cys peroxiredoxin	MA20_35715	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SYD2_k127_5862338_9	682795.AciX8_0370	1.786e-85	291.0	COG3494@1|root,COG3494@2|Bacteria,3Y3KI@57723|Acidobacteria,2JIMV@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
SYD2_k127_5862338_10	1267534.KB906754_gene3343	3.592e-77	271.0	COG1043@1|root,COG1043@2|Bacteria,3Y33C@57723|Acidobacteria,2JI06@204432|Acidobacteriia	204432|Acidobacteriia	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
SYD2_k127_5862338_12	1198114.AciX9_0678	8.661e-45	167.0	COG0764@1|root,COG0764@2|Bacteria,3Y4CG@57723|Acidobacteria,2JJ97@204432|Acidobacteriia	204432|Acidobacteriia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SYD2_k127_5862338_18	926566.Terro_0306	1.897e-06	57.0	COG2825@1|root,COG2825@2|Bacteria,3Y4WC@57723|Acidobacteria,2JJHF@204432|Acidobacteriia	204432|Acidobacteriia	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SYD2_k127_5862338_15	1267534.KB906754_gene3361	1.81e-10	70.0	COG2825@1|root,COG2825@2|Bacteria,3Y56P@57723|Acidobacteria,2JP1P@204432|Acidobacteriia	204432|Acidobacteriia	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SYD2_k127_5862338_19	234267.Acid_6470	0.0003843	49.0	COG4775@1|root,COG4775@2|Bacteria,3Y2Q9@57723|Acidobacteria	57723|Acidobacteria	M	Surface antigen variable number	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SYD2_k127_5871228_4	1123508.JH636453_gene5827	1.244e-127	457.0	COG4447@1|root,COG5276@1|root,COG4447@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_2,DUF1566,DUF4347,He_PIG
SYD2_k127_5871228_8	438753.AZC_1301	1.17e-96	359.0	COG2730@1|root,COG2730@2|Bacteria,1QU12@1224|Proteobacteria,2TYN6@28211|Alphaproteobacteria,3F11R@335928|Xanthobacteraceae	28211|Alphaproteobacteria	G	CBD_II	-	-	3.2.1.14,3.2.1.4	ko:K01179,ko:K01183	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R01206,R02334,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH18,GH5,GH9	-	CBM_2,Calx-beta,Cellulase
SYD2_k127_5871228_5	1198452.Jab_2c05080	7.331e-124	418.0	COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,1MYCW@1224|Proteobacteria,2WF6V@28216|Betaproteobacteria,476HS@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA
SYD2_k127_5871228_20	269799.Gmet_3540	4.658e-24	120.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,43UDK@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SYD2_k127_5871228_17	1123253.AUBD01000002_gene1205	3.374e-43	183.0	COG3591@1|root,COG3591@2|Bacteria,1RF3X@1224|Proteobacteria,1S6V4@1236|Gammaproteobacteria,1X411@135614|Xanthomonadales	135614|Xanthomonadales	E	Trypsin-like peptidase domain	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
SYD2_k127_5871228_19	272123.Anacy_5220	1.244e-30	139.0	COG2931@1|root,COG4625@1|root,COG2931@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	3.2.1.4	ko:K01179,ko:K07004	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calx-beta,Laminin_G_3,PATR
SYD2_k127_5871228_15	644282.Deba_0613	6.315e-57	213.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,42PK2@68525|delta/epsilon subdivisions,2WP9Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	2.4.1.349	ko:K12994	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SYD2_k127_5871228_25	1353529.M899_0151	3.582e-14	85.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,DUF4953,DUF5117,DUF5118,MACPF,Peptidase_M10,Peptidase_M43
SYD2_k127_5871228_16	4533.OB02G40700.1	2.099e-50	200.0	COG3934@1|root,2QS4Q@2759|Eukaryota,37PFM@33090|Viridiplantae,3GCR2@35493|Streptophyta,3KM9V@4447|Liliopsida,3I69W@38820|Poales	35493|Streptophyta	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004567,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010412,GO:0015923,GO:0016052,GO:0016787,GO:0016798,GO:0016985,GO:0016998,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046355,GO:0071554,GO:0071704,GO:1901575	3.2.1.78	ko:K19355	ko00051,map00051	-	R01332	RC00467	ko00000,ko00001,ko01000	-	-	-	Cellulase
SYD2_k127_5871228_1	1242864.D187_008887	5.395e-175	567.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,EF-hand_5,Metallophos
SYD2_k127_5871228_7	861299.J421_4076	3.497e-120	400.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SYD2_k127_5871228_12	1283299.AUKG01000002_gene4588	5.989e-76	267.0	COG3320@1|root,COG3320@2|Bacteria,2GKZY@201174|Actinobacteria,4CPPS@84995|Rubrobacteria	84995|Rubrobacteria	Q	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
SYD2_k127_5871228_13	1173022.Cri9333_2854	1.586e-75	258.0	COG0259@1|root,COG0259@2|Bacteria,1G0HC@1117|Cyanobacteria,1HA00@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.pdxH	PNP_phzG_C,Putative_PNPOx
SYD2_k127_5871228_2	1382359.JIAL01000001_gene3046	3.463e-133	439.0	COG1160@1|root,COG1160@2|Bacteria,3Y3AC@57723|Acidobacteria,2JIAS@204432|Acidobacteriia	204432|Acidobacteriia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SYD2_k127_5871228_3	269799.Gmet_0852	8.629e-132	433.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,43TNC@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SYD2_k127_5871228_22	243275.TDE_0682	1.89e-18	89.0	COG1862@1|root,COG1862@2|Bacteria,2J8D6@203691|Spirochaetes	203691|Spirochaetes	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SYD2_k127_5871228_6	204669.Acid345_0146	2.011e-120	407.0	COG0342@1|root,COG0342@2|Bacteria,3Y37S@57723|Acidobacteria,2JHJC@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SYD2_k127_5871228_14	1198114.AciX9_3623	1.025e-73	261.0	COG0341@1|root,COG0341@2|Bacteria,3Y2ZT@57723|Acidobacteria,2JHZF@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SYD2_k127_5871228_24	682795.AciX8_4403	2.529e-14	82.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria,2JI38@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SYD2_k127_5871228_11	234267.Acid_1281	5.696e-78	269.0	COG0811@1|root,COG0811@2|Bacteria,3Y2M4@57723|Acidobacteria	57723|Acidobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
SYD2_k127_5871228_21	204669.Acid345_0150	2.094e-20	97.0	COG0848@1|root,COG0848@2|Bacteria,3Y4TE@57723|Acidobacteria,2JJKY@204432|Acidobacteriia	204432|Acidobacteriia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SYD2_k127_5871228_26	378806.STAUR_2248	9.475e-12	72.0	COG0848@1|root,COG0848@2|Bacteria,1Q1RQ@1224|Proteobacteria,437EZ@68525|delta/epsilon subdivisions,2X2MA@28221|Deltaproteobacteria,2Z03D@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SYD2_k127_5871228_23	204669.Acid345_0152	6.624e-17	91.0	COG0457@1|root,COG0457@2|Bacteria,3Y3N5@57723|Acidobacteria,2JISD@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
SYD2_k127_5871228_0	234267.Acid_1285	2.029e-252	797.0	COG0317@1|root,COG0317@2|Bacteria,3Y38Q@57723|Acidobacteria	57723|Acidobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SYD2_k127_5871228_10	935863.AWZR01000005_gene2181	7.445e-79	280.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,1X50I@135614|Xanthomonadales	135614|Xanthomonadales	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SYD2_k127_5871228_28	1254432.SCE1572_51510	5.689e-07	59.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,2YVYE@29|Myxococcales	28221|Deltaproteobacteria	CO	Redoxin	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
SYD2_k127_5871228_18	536227.CcarbDRAFT_3686	1.731e-33	139.0	COG2068@1|root,COG2068@2|Bacteria,1UY6E@1239|Firmicutes,249PV@186801|Clostridia,36FU4@31979|Clostridiaceae	186801|Clostridia	S	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,NTP_transf_3
SYD2_k127_5871228_9	1382306.JNIM01000001_gene1024	6.514e-93	316.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SYD2_k127_5895171_3	56780.SYN_00437	2.297e-101	338.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2MQ7W@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SYD2_k127_5895171_17	903818.KI912268_gene1547	1.678e-22	104.0	COG1923@1|root,COG1923@2|Bacteria,3Y5JI@57723|Acidobacteria	57723|Acidobacteria	S	Hfq protein	-	-	-	-	-	-	-	-	-	-	-	-	Hfq
SYD2_k127_5895171_6	555079.Toce_0654	3.757e-84	291.0	COG1995@1|root,COG1995@2|Bacteria,1TQGT@1239|Firmicutes,24A12@186801|Clostridia,42FJX@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
SYD2_k127_5895171_19	1347087.CBYO010000001_gene34	5.171e-18	89.0	COG0745@1|root,COG2972@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2972@2|Bacteria,COG5002@2|Bacteria,1UIHJ@1239|Firmicutes,4ISI2@91061|Bacilli	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	4HB_MCP_1,GAF_2,HAMP,HATPase_c,HisKA,His_kinase,Response_reg
SYD2_k127_5895171_25	530564.Psta_3671	0.0009819	49.0	COG2165@1|root,COG2165@2|Bacteria,2J0S3@203682|Planctomycetes	203682|Planctomycetes	U	general secretion pathway protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
SYD2_k127_5895171_14	316067.Geob_3083	2.615e-34	147.0	COG0745@1|root,COG0745@2|Bacteria,1NER5@1224|Proteobacteria,42VHC@68525|delta/epsilon subdivisions,2WSGQ@28221|Deltaproteobacteria,43UMT@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SYD2_k127_5895171_0	373903.Hore_14590	1.169e-288	913.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3WA6Y@53433|Halanaerobiales	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SYD2_k127_5895171_8	485916.Dtox_2252	8.811e-67	238.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,26046@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
SYD2_k127_5895171_18	768710.DesyoDRAFT_1194	7.388e-22	100.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia,2617B@186807|Peptococcaceae	186801|Clostridia	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SYD2_k127_5895171_15	1157490.EL26_22765	2.829e-31	125.0	COG4539@1|root,COG4539@2|Bacteria,1VJFX@1239|Firmicutes,4HQE3@91061|Bacilli,27A12@186823|Alicyclobacillaceae	91061|Bacilli	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
SYD2_k127_5895171_13	485913.Krac_9005	8.732e-38	153.0	COG1975@1|root,COG1975@2|Bacteria,2G6H0@200795|Chloroflexi	200795|Chloroflexi	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SYD2_k127_5895171_10	633149.Bresu_1257	1.711e-55	201.0	2DEWU@1|root,2ZPJP@2|Bacteria,1N6PP@1224|Proteobacteria,2UI8P@28211|Alphaproteobacteria,2KJAY@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5895171_4	1183438.GKIL_3324	5.086e-97	331.0	COG0477@1|root,COG2814@2|Bacteria,1G2N2@1117|Cyanobacteria	1117|Cyanobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SYD2_k127_5895171_11	330214.NIDE1725	4.744e-43	169.0	COG4447@1|root,COG4447@2|Bacteria,3J16A@40117|Nitrospirae	40117|Nitrospirae	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SYD2_k127_5895171_1	234267.Acid_6747	7.401e-262	816.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria	57723|Acidobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SYD2_k127_5895171_12	240015.ACP_0720	1.69e-39	149.0	COG0234@1|root,COG0234@2|Bacteria,3Y4VQ@57723|Acidobacteria,2JJEF@204432|Acidobacteriia	204432|Acidobacteriia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SYD2_k127_5895171_23	234267.Acid_5252	3.292e-05	49.0	COG3829@1|root,COG3829@2|Bacteria,3Y5ZF@57723|Acidobacteria	57723|Acidobacteria	KT	PFAM helix-turn-helix, Fis-type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8
SYD2_k127_5895171_2	1382359.JIAL01000001_gene2033	1.343e-108	359.0	COG0152@1|root,COG0152@2|Bacteria,3Y2KX@57723|Acidobacteria,2JIG6@204432|Acidobacteriia	204432|Acidobacteriia	F	SAICAR synthetase	purC	-	6.3.2.6,6.3.4.13	ko:K01923,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SYD2_k127_5895171_16	1444309.JAQG01000004_gene3592	8.078e-26	112.0	COG2318@1|root,COG2318@2|Bacteria,1VW3T@1239|Firmicutes,4HWQI@91061|Bacilli,26Y17@186822|Paenibacillaceae	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SYD2_k127_5895171_22	929713.NIASO_06150	5.854e-06	55.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	osmY_2	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
SYD2_k127_5895171_5	1174528.JH992898_gene2447	3.489e-87	293.0	COG3467@1|root,COG3467@2|Bacteria,1G4RC@1117|Cyanobacteria,1JJWX@1189|Stigonemataceae	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SYD2_k127_5895171_9	626887.J057_17720	1.362e-62	224.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,1RNJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SYD2_k127_5895171_7	1166948.JPZL01000001_gene3115	1.135e-72	254.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,1RNJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	-	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku,Rho_N
SYD2_k127_5895171_20	946235.CAER01000014_gene1290	4.76e-10	63.0	2EFZF@1|root,339RM@2|Bacteria,1VMG6@1239|Firmicutes,4HR8G@91061|Bacilli,23MAZ@182709|Oceanobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5903181_0	1267534.KB906756_gene278	3.858e-182	586.0	COG0138@1|root,COG0138@2|Bacteria,3Y2QI@57723|Acidobacteria,2JHSU@204432|Acidobacteriia	204432|Acidobacteriia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SYD2_k127_5914684_1	633149.Bresu_2368	9.178e-30	130.0	COG1876@1|root,COG1876@2|Bacteria,1N1CQ@1224|Proteobacteria,2U7GA@28211|Alphaproteobacteria,2KGBW@204458|Caulobacterales	204458|Caulobacterales	M	PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,VanY
SYD2_k127_5914684_3	1305737.JAFX01000001_gene2397	0.0002544	44.0	COG1943@1|root,COG1943@2|Bacteria,4NPPG@976|Bacteroidetes,47RSC@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SYD2_k127_5914684_0	289376.THEYE_A0010	7.437e-213	675.0	COG0504@1|root,COG0504@2|Bacteria,3J0FB@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SYD2_k127_5914684_2	926561.KB900617_gene2131	1.901e-21	98.0	COG1212@1|root,COG1212@2|Bacteria,1TQU3@1239|Firmicutes,24H2B@186801|Clostridia,3WAKF@53433|Halanaerobiales	186801|Clostridia	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
SYD2_k127_591901_12	1123270.ATUR01000003_gene833	3.909e-46	171.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2JZZC@204457|Sphingomonadales	204457|Sphingomonadales	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SYD2_k127_591901_8	1120934.KB894425_gene1116	2.054e-62	229.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2I5Z7@201174|Actinobacteria,4E2FS@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	2.4.1.289	ko:K16870	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glyco_trans_2_3,Glycos_transf_2
SYD2_k127_591901_17	204669.Acid345_2641	7.791e-10	61.0	COG5485@1|root,COG5485@2|Bacteria,3Y5VH@57723|Acidobacteria,2JNTY@204432|Acidobacteriia	204432|Acidobacteriia	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SYD2_k127_591901_7	1499967.BAYZ01000014_gene6405	1.709e-73	259.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_12,PP-binding,ketoacyl-synt
SYD2_k127_591901_10	696281.Desru_2828	1.357e-56	207.0	COG0500@1|root,COG0500@2|Bacteria,1VJS9@1239|Firmicutes,24TBM@186801|Clostridia	186801|Clostridia	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SYD2_k127_591901_15	1089553.Tph_c14180	6.608e-10	72.0	COG1807@1|root,COG1807@2|Bacteria,1V1HJ@1239|Firmicutes,249BG@186801|Clostridia,42HAV@68295|Thermoanaerobacterales	186801|Clostridia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SYD2_k127_591901_3	391612.CY0110_23846	4.234e-113	373.0	COG0463@1|root,COG0463@2|Bacteria,1G03Y@1117|Cyanobacteria,3KGSX@43988|Cyanothece	1117|Cyanobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
SYD2_k127_591901_11	247490.KSU1_D0299	4.685e-49	185.0	COG0500@1|root,COG2226@2|Bacteria,2J1BW@203682|Planctomycetes	203682|Planctomycetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SYD2_k127_591901_6	1321781.HMPREF1985_01955	1.25e-79	290.0	COG0438@1|root,COG0438@2|Bacteria,1V1BU@1239|Firmicutes,4H41Z@909932|Negativicutes	909932|Negativicutes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SYD2_k127_591901_14	449447.MAE_32920	1.48e-13	83.0	COG2244@1|root,COG2244@2|Bacteria,1G2BA@1117|Cyanobacteria	1117|Cyanobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SYD2_k127_591901_0	517418.Ctha_2023	6.159e-172	560.0	COG0367@1|root,COG0367@2|Bacteria,1FDEI@1090|Chlorobi	1090|Chlorobi	F	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SYD2_k127_591901_4	330214.NIDE3009	5.138e-99	349.0	COG5360@1|root,COG5360@2|Bacteria	2|Bacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
SYD2_k127_591901_1	1183438.GKIL_0464	4.207e-164	528.0	COG0677@1|root,COG0677@2|Bacteria,1G4FW@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SYD2_k127_591901_2	1267535.KB906767_gene3318	9.061e-132	431.0	COG0665@1|root,COG0665@2|Bacteria,3Y6FK@57723|Acidobacteria,2JKN4@204432|Acidobacteriia	204432|Acidobacteriia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SYD2_k127_591901_5	234267.Acid_3432	4.276e-93	328.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_3,SpoIIE
SYD2_k127_591901_18	349124.Hhal_0678	5.087e-09	64.0	COG1714@1|root,COG1714@2|Bacteria,1N4N8@1224|Proteobacteria,1S9C5@1236|Gammaproteobacteria,1WYQZ@135613|Chromatiales	135613|Chromatiales	S	pfam rdd	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SYD2_k127_591901_16	485913.Krac_3396	7.008e-10	72.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,MFS_1
SYD2_k127_591901_9	479434.Sthe_1246	7.15e-62	233.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi,27Z13@189775|Thermomicrobia	189775|Thermomicrobia	KLT	PQQ-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
SYD2_k127_591901_13	324602.Caur_3814	2.814e-19	95.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi,375YC@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SYD2_k127_5919660_2	639282.DEFDS_0313	1.346e-31	131.0	COG0179@1|root,COG0179@2|Bacteria,2GF3S@200930|Deferribacteres	200930|Deferribacteres	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SYD2_k127_5919660_0	765420.OSCT_1210	3.408e-235	743.0	COG0281@1|root,COG0281@2|Bacteria,2G65R@200795|Chloroflexi,376YS@32061|Chloroflexia	32061|Chloroflexia	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
SYD2_k127_5919660_1	1454004.AW11_02556	4.926e-183	580.0	COG0626@1|root,COG0626@2|Bacteria	2|Bacteria	E	cystathionine gamma-synthase activity	megL	-	2.5.1.48,2.5.1.49,4.4.1.11,4.4.1.8	ko:K01739,ko:K01740,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01287,R01288,R02408,R02508,R03217,R03260,R04770,R04859,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02821,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SYD2_k127_5971775_8	401053.AciPR4_0762	3.039e-25	109.0	COG0736@1|root,COG0736@2|Bacteria,3Y590@57723|Acidobacteria,2JJPD@204432|Acidobacteriia	204432|Acidobacteriia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SYD2_k127_5971775_7	1408423.JHYA01000005_gene1842	1.079e-44	174.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,4H26Q@909932|Negativicutes	909932|Negativicutes	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SYD2_k127_5971775_11	521674.Plim_0196	1.353e-13	78.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	DsbC,LGT,Redoxin
SYD2_k127_5971775_5	1267535.KB906767_gene1613	2.913e-86	297.0	COG0820@1|root,COG0820@2|Bacteria,3Y3HQ@57723|Acidobacteria,2JIT9@204432|Acidobacteriia	204432|Acidobacteriia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
SYD2_k127_5971775_10	794903.OPIT5_29910	6.966e-17	85.0	2E0PR@1|root,32W8G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5971775_3	234267.Acid_1509	5.609e-110	376.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5971775_0	234267.Acid_1509	1.48e-143	473.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5971775_13	1340493.JNIF01000004_gene374	0.0008605	49.0	297M3@1|root,2ZUU3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5971775_12	1267534.KB906754_gene3732	1.438e-10	72.0	2DTV5@1|root,33MT0@2|Bacteria,3Y5UW@57723|Acidobacteria,2JNBS@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5971775_2	595460.RRSWK_02466	5.112e-113	375.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
SYD2_k127_5971775_1	330214.NIDE0474	3.449e-115	386.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
SYD2_k127_5971775_6	290397.Adeh_0738	1.688e-64	234.0	COG0122@1|root,COG0122@2|Bacteria,1P0FP@1224|Proteobacteria	1224|Proteobacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SYD2_k127_5971775_9	1211114.ALIP01000131_gene1967	2.358e-17	84.0	COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1X4VE@135614|Xanthomonadales	135614|Xanthomonadales	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
SYD2_k127_5971775_4	316274.Haur_0016	3.274e-101	340.0	COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi,376HN@32061|Chloroflexia	200795|Chloroflexi	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SYD2_k127_5975644_1	247490.KSU1_D0244	9.342e-22	97.0	COG2121@1|root,COG2121@2|Bacteria,2IZW3@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
SYD2_k127_5975644_0	1297863.APJF01000008_gene636	1.899e-126	417.0	COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,2TRNW@28211|Alphaproteobacteria,3JSXW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SYD2_k127_5976869_2	309799.DICTH_1909	1.164e-10	64.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	nadE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SYD2_k127_5976869_1	880073.Calab_3784	1.309e-27	120.0	COG1986@1|root,COG1986@2|Bacteria,2NS1I@2323|unclassified Bacteria	2|Bacteria	F	Protein of unknown function DUF84	yjjX	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564	-	-	-	-	-	-	-	-	-	iECO111_1330.ECO111_5255	NTPase_I-T
SYD2_k127_5976869_0	1379698.RBG1_1C00001G0513	4.014e-149	482.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SYD2_k127_5977117_5	335543.Sfum_3369	6.799e-64	240.0	COG4581@1|root,COG4581@2|Bacteria,1QUPR@1224|Proteobacteria,42NSH@68525|delta/epsilon subdivisions,2WKD7@28221|Deltaproteobacteria,2MQUA@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DSHCT	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,DUF3516,Helicase_C
SYD2_k127_5977117_1	706587.Desti_4790	2.128e-90	313.0	2C5WB@1|root,2Z7IZ@2|Bacteria,1RCRD@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5977117_3	498761.HM1_1931	3.928e-66	235.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia	186801|Clostridia	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
SYD2_k127_5977117_9	530564.Psta_4236	1.689e-19	97.0	2EJ4R@1|root,33CVZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5977117_0	1254432.SCE1572_13105	1.127e-109	370.0	COG2308@1|root,COG2308@2|Bacteria,1P9A0@1224|Proteobacteria,42PIM@68525|delta/epsilon subdivisions,2WKI0@28221|Deltaproteobacteria,2Z1SA@29|Myxococcales	28221|Deltaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5977117_8	234267.Acid_1335	1.887e-31	128.0	COG2315@1|root,COG2315@2|Bacteria,3Y5I0@57723|Acidobacteria	57723|Acidobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SYD2_k127_5977117_10	1173027.Mic7113_3240	6.845e-05	52.0	COG4276@1|root,COG4276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SYD2_k127_5977117_6	1407650.BAUB01000004_gene979	4.02e-48	184.0	COG0508@1|root,COG0508@2|Bacteria,1G0YZ@1117|Cyanobacteria,1H4BZ@1129|Synechococcus	1117|Cyanobacteria	C	dehydrogenase complex catalyzes the overall conversion of	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_5977117_2	671143.DAMO_1661	3.168e-86	297.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	mauG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
SYD2_k127_5977117_4	215803.DB30_2740	5.506e-66	231.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,42QV7@68525|delta/epsilon subdivisions,2WMPC@28221|Deltaproteobacteria,2YVDJ@29|Myxococcales	28221|Deltaproteobacteria	C	Iron/manganese superoxide dismutases, C-terminal domain	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SYD2_k127_5977117_7	204669.Acid345_4342	1.074e-34	148.0	COG3748@1|root,COG3748@2|Bacteria	2|Bacteria	S	Urate oxidase N-terminal	MA20_17625	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
SYD2_k127_6002676_4	1122605.KB893643_gene585	5.587e-16	87.0	2EIK5@1|root,33CBF@2|Bacteria,4NV2P@976|Bacteroidetes,1IU6J@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6002676_1	1267535.KB906767_gene245	1.67e-68	237.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SYD2_k127_6002676_5	443598.AUFA01000010_gene356	1.98e-05	57.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	acfD	-	-	ko:K02004,ko:K10939,ko:K12257,ko:K14393	ko02024,ko03060,ko03070,ko05111,map02024,map03060,map03070,map05111	M00258,M00335	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	2.A.21.7,2.A.6.4,3.A.1	-	-	DUF4092,FtsX,M60-like_N,MacB_PCD,Peptidase_M60
SYD2_k127_6002676_3	608538.HTH_0931	1.262e-46	177.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	fdoI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494	-	ko:K00127,ko:K08350	ko00630,ko00680,ko01100,ko01120,ko01200,ko02020,map00630,map00680,map01100,map01120,map01200,map02020	-	R00519	RC02796	ko00000,ko00001	5.A.3.2	-	iEC042_1314.EC042_1608,iECED1_1282.ECED1_1627,iECNA114_1301.ECNA114_3649,iECSF_1327.ECSF_1390,iECUMN_1333.ECUMN_1730,ic_1306.c1907	Ni_hydr_CYTB
SYD2_k127_6002676_0	1231391.AMZF01000009_gene1759	1.198e-95	322.0	COG0437@1|root,COG0437@2|Bacteria,1QUMM@1224|Proteobacteria,2WHXZ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K07307	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11
SYD2_k127_6002676_2	234267.Acid_0837	5.025e-52	184.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,3Y47M@57723|Acidobacteria	57723|Acidobacteria	C	Molydopterin dinucleotide binding domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
SYD2_k127_6080194_2	204669.Acid345_3661	1.22e-81	273.0	COG0192@1|root,COG0192@2|Bacteria,3Y45C@57723|Acidobacteria,2JJ0A@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SYD2_k127_6080194_0	211165.AJLN01000051_gene4874	2.595e-201	634.0	COG0499@1|root,COG0499@2|Bacteria,1G1MN@1117|Cyanobacteria,1JJ5C@1189|Stigonemataceae	1117|Cyanobacteria	H	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SYD2_k127_6080194_1	240015.ACP_0114	4.608e-84	306.0	COG0795@1|root,COG0795@2|Bacteria,3Y2F9@57723|Acidobacteria,2JI5V@204432|Acidobacteriia	204432|Acidobacteriia	S	Permease, YjgP YjgQ	-	-	-	-	-	-	-	-	-	-	-	-	YjgP_YjgQ
SYD2_k127_6080194_3	216816.GS08_07100	2.171e-20	100.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CZCN@85004|Bifidobacteriales	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SYD2_k127_6080194_5	1267533.KB906741_gene608	6.304e-17	86.0	2DTIS@1|root,33KJ1@2|Bacteria,3Y5U4@57723|Acidobacteria,2JN6V@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6080194_4	289376.THEYE_A0955	3.935e-17	82.0	COG3876@1|root,COG3876@2|Bacteria	2|Bacteria	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
SYD2_k127_6103105_0	1122176.KB903551_gene4256	3.349e-100	341.0	COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,1IU97@117747|Sphingobacteriia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
SYD2_k127_6146058_3	316067.Geob_0331	4.939e-23	101.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2WP7G@28221|Deltaproteobacteria,43V0M@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SYD2_k127_6146058_1	1122179.KB890458_gene744	2.083e-93	325.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1IPY5@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SYD2_k127_6146058_2	234267.Acid_1082	3.069e-50	190.0	COG0424@1|root,COG0424@2|Bacteria,3Y4ZU@57723|Acidobacteria	57723|Acidobacteria	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SYD2_k127_6146058_6	926692.AZYG01000047_gene2700	0.000488	48.0	COG5512@1|root,COG5512@2|Bacteria,1V9FF@1239|Firmicutes,24RDV@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SYD2_k127_6146058_4	269799.Gmet_0076	3.127e-14	76.0	COG0721@1|root,COG0721@2|Bacteria,1QE6H@1224|Proteobacteria,42VPR@68525|delta/epsilon subdivisions,2WRP0@28221|Deltaproteobacteria,43V4D@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	iAF987.Gmet_0076	Glu-tRNAGln
SYD2_k127_6146058_0	204669.Acid345_0501	1.124e-175	563.0	COG0154@1|root,COG0154@2|Bacteria,3Y2PE@57723|Acidobacteria,2JIE0@204432|Acidobacteriia	204432|Acidobacteriia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SYD2_k127_6146484_0	648996.Theam_1567	9.396e-220	690.0	COG0458@1|root,COG0458@2|Bacteria,2G3RR@200783|Aquificae	200783|Aquificae	F	PFAM Carbamoyl-phosphate synthase L chain	carB2	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SYD2_k127_6146484_4	1267534.KB906759_gene1869	3.694e-30	126.0	COG0526@1|root,COG0526@2|Bacteria,3Y56Q@57723|Acidobacteria,2JJND@204432|Acidobacteriia	204432|Acidobacteriia	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
SYD2_k127_6146484_6	485917.Phep_2880	1.659e-19	96.0	2EVCJ@1|root,33NT1@2|Bacteria,4P2RM@976|Bacteroidetes,1IXDP@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6146484_5	756272.Plabr_1807	1.849e-22	107.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2IXA1@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,HATPase_c,HisKA
SYD2_k127_6146484_2	335543.Sfum_3514	1.45e-42	163.0	COG3034@1|root,COG3034@2|Bacteria,1QTMV@1224|Proteobacteria,42W1K@68525|delta/epsilon subdivisions,2X5QE@28221|Deltaproteobacteria,2MS74@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SYD2_k127_6146484_3	639030.JHVA01000001_gene746	6.059e-42	163.0	COG3375@1|root,COG3375@2|Bacteria,3Y41E@57723|Acidobacteria,2JI86@204432|Acidobacteriia	204432|Acidobacteriia	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SYD2_k127_6146484_1	1267535.KB906767_gene2507	1.656e-52	190.0	COG0272@1|root,COG0272@2|Bacteria,3Y2UR@57723|Acidobacteria,2JHN1@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SYD2_k127_6152049_2	926550.CLDAP_40310	7.832e-44	170.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K16703	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SYD2_k127_6152049_0	457429.ABJI02000493_gene6972	9.753e-113	398.0	COG1216@1|root,COG2227@1|root,COG1216@2|Bacteria,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
SYD2_k127_6152049_3	391625.PPSIR1_25921	8.914e-19	102.0	2DM58@1|root,31S4C@2|Bacteria,1RGAH@1224|Proteobacteria,431QP@68525|delta/epsilon subdivisions,2WWXE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6152049_1	864069.MicloDRAFT_00025890	4.921e-88	321.0	COG1215@1|root,COG1215@2|Bacteria,1NDPE@1224|Proteobacteria,2TSCT@28211|Alphaproteobacteria,1JUA4@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM Glycosyl transferase family 2	exoA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K16557	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SYD2_k127_6152049_4	926569.ANT_11540	6.164e-12	79.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SYD2_k127_6152049_5	234267.Acid_4860	0.0001577	50.0	COG0399@1|root,COG0399@2|Bacteria,3Y2QT@57723|Acidobacteria	57723|Acidobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SYD2_k127_6162306_1	204669.Acid345_3005	2.754e-203	662.0	COG0457@1|root,COG1305@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,3Y5KB@57723|Acidobacteria,2JHVK@204432|Acidobacteriia	204432|Acidobacteriia	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
SYD2_k127_6162306_0	204669.Acid345_3006	6.485e-283	877.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,3Y2Q1@57723|Acidobacteria,2JKFT@204432|Acidobacteriia	204432|Acidobacteriia	CJ	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SYD2_k127_6169029_5	251229.Chro_3946	0.0007844	42.0	COG0399@1|root,COG0399@2|Bacteria,1GJK5@1117|Cyanobacteria,3VKFF@52604|Pleurocapsales	1117|Cyanobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SYD2_k127_6169029_1	357808.RoseRS_3801	1.006e-69	248.0	COG1300@1|root,COG1300@2|Bacteria,2G8HV@200795|Chloroflexi,37546@32061|Chloroflexia	32061|Chloroflexia	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
SYD2_k127_6169029_0	1267535.KB906767_gene392	4.682e-96	327.0	COG3643@1|root,COG3643@2|Bacteria,3Y3HP@57723|Acidobacteria,2JIP9@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Formiminotransferase domain	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_N
SYD2_k127_6169029_2	706587.Desti_3711	7.596e-18	94.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SYD2_k127_6169029_4	357808.RoseRS_3392	9.54e-07	62.0	COG1413@1|root,COG1413@2|Bacteria,2G6UU@200795|Chloroflexi	200795|Chloroflexi	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SYD2_k127_6169029_3	1038859.AXAU01000001_gene2613	7.165e-10	72.0	2AKTJ@1|root,31BKK@2|Bacteria,1NYB1@1224|Proteobacteria,2UTN8@28211|Alphaproteobacteria,3K4H7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6195491_1	221288.JH992901_gene5748	8.872e-159	508.0	COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
SYD2_k127_6195491_3	221288.JH992901_gene5747	1.249e-145	477.0	28KMN@1|root,2ZA61@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062,TIR_2
SYD2_k127_6195491_2	1121438.JNJA01000008_gene3867	7.084e-149	501.0	COG1226@1|root,COG2114@1|root,COG1226@2|Bacteria,COG2114@2|Bacteria,1R86S@1224|Proteobacteria,4317C@68525|delta/epsilon subdivisions,2WWWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6195491_4	1380355.JNIJ01000051_gene2204	3.912e-107	370.0	COG0457@1|root,COG0457@2|Bacteria,1N06S@1224|Proteobacteria,2TQVV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863,TPR_8
SYD2_k127_6195491_8	383372.Rcas_2374	1.346e-06	56.0	2A5RH@1|root,30UGG@2|Bacteria,2GAGV@200795|Chloroflexi,3762W@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF1772)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772
SYD2_k127_6195491_6	671143.DAMO_2379	1.55e-54	196.0	COG0822@1|root,COG0822@2|Bacteria,2NPXN@2323|unclassified Bacteria	2|Bacteria	C	NifU-like N terminal domain	nifU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SYD2_k127_6195491_0	1266925.JHVX01000003_gene433	3.406e-180	573.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2VIQW@28216|Betaproteobacteria,371MB@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SYD2_k127_6195491_5	671143.DAMO_2381	1.345e-105	358.0	COG0719@1|root,COG0719@2|Bacteria,2NPGC@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufD	sufD	GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144	UPF0051
SYD2_k127_6195491_7	945713.IALB_2894	7.549e-52	184.0	COG0396@1|root,COG0396@2|Bacteria	2|Bacteria	O	ATPase activity	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	ABC_tran
SYD2_k127_6220608_0	1192034.CAP_5918	5.396e-225	707.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,2YY2T@29|Myxococcales	28221|Deltaproteobacteria	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SYD2_k127_6220608_3	1507.HMPREF0262_02874	1.542e-23	106.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,36JKN@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
SYD2_k127_6220608_1	204669.Acid345_3614	6.057e-113	383.0	COG0128@1|root,COG0128@2|Bacteria,3Y3RH@57723|Acidobacteria,2JI7W@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SYD2_k127_6220608_2	240015.ACP_2974	2.258e-24	109.0	COG2172@1|root,COG2172@2|Bacteria,3Y4TY@57723|Acidobacteria,2JJGJ@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SYD2_k127_6226943_0	864051.BurJ1DRAFT_3973	1.985e-119	408.0	COG5434@1|root,COG5434@2|Bacteria,1R1VR@1224|Proteobacteria	1224|Proteobacteria	M	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
SYD2_k127_6226943_9	446465.Bfae_02030	7.178e-07	61.0	COG2334@1|root,COG2334@2|Bacteria,2IKR1@201174|Actinobacteria	201174|Actinobacteria	S	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	-	-	-	-	-	-	-	-	-	-	-	-	APH
SYD2_k127_6226943_1	864051.BurJ1DRAFT_3969	3.46e-96	334.0	COG4671@1|root,COG4671@2|Bacteria,1NE6T@1224|Proteobacteria,2W2IM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
SYD2_k127_6226943_4	1116472.MGMO_162c00100	9.005e-64	227.0	COG0726@1|root,COG0726@2|Bacteria,1R5QW@1224|Proteobacteria	1224|Proteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2334,Polysacc_deac_1
SYD2_k127_6226943_2	69395.JQLZ01000001_gene2928	2.258e-89	306.0	COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,2U3UB@28211|Alphaproteobacteria,2KI8X@204458|Caulobacterales	204458|Caulobacterales	K	Arabinose-binding domain of AraC transcription regulator, N-term	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
SYD2_k127_6226943_5	1267533.KB906736_gene960	9.719e-54	194.0	2A52F@1|root,30N7U@2|Bacteria,3Y80I@57723|Acidobacteria,2JN1S@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6226943_6	1094715.CM001373_gene3232	4.948e-45	168.0	COG0697@1|root,COG0803@1|root,COG0697@2|Bacteria,COG0803@2|Bacteria,1N3FA@1224|Proteobacteria,1RYMI@1236|Gammaproteobacteria,1JE2J@118969|Legionellales	118969|Legionellales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SYD2_k127_6226943_3	375286.mma_1733	2.216e-75	261.0	COG0697@1|root,COG0803@1|root,COG0697@2|Bacteria,COG0803@2|Bacteria,1N3FA@1224|Proteobacteria,2VHAD@28216|Betaproteobacteria,476CV@75682|Oxalobacteraceae	28216|Betaproteobacteria	EG	EamA-like transporter family	cnrT	-	-	-	-	-	-	-	-	-	-	-	EamA
SYD2_k127_6226943_8	234267.Acid_3868	2.39e-08	55.0	COG0053@1|root,COG0053@2|Bacteria,3Y5VF@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SYD2_k127_6226943_7	266117.Rxyl_2819	1.133e-10	63.0	COG2345@1|root,COG2345@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
SYD2_k127_6266742_2	1340493.JNIF01000004_gene350	6.543e-82	282.0	COG0224@1|root,COG0224@2|Bacteria,3Y3MN@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SYD2_k127_6266742_0	1267535.KB906767_gene3120	3.016e-233	730.0	COG0056@1|root,COG0056@2|Bacteria,3Y2R6@57723|Acidobacteria,2JIEV@204432|Acidobacteriia	204432|Acidobacteriia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SYD2_k127_6266742_6	234267.Acid_0462	2.173e-29	126.0	COG0712@1|root,COG0712@2|Bacteria,3Y4Z4@57723|Acidobacteria	57723|Acidobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SYD2_k127_6266742_9	234267.Acid_0461	6.79e-15	84.0	COG0711@1|root,COG0711@2|Bacteria,3Y4UJ@57723|Acidobacteria	57723|Acidobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SYD2_k127_6266742_11	443144.GM21_4040	2.427e-06	55.0	COG0711@1|root,COG0711@2|Bacteria,1NA9K@1224|Proteobacteria,42VN2@68525|delta/epsilon subdivisions,2WR8C@28221|Deltaproteobacteria,43VA3@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpX	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SYD2_k127_6266742_8	234267.Acid_1093	6.727e-15	75.0	COG0230@1|root,COG0230@2|Bacteria,3Y5W7@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SYD2_k127_6266742_12	868864.Dester_0620	0.0008164	48.0	COG0594@1|root,COG0594@2|Bacteria,2G4D4@200783|Aquificae	200783|Aquificae	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SYD2_k127_6266742_7	653733.Selin_0823	2.493e-25	108.0	COG0759@1|root,COG0759@2|Bacteria	2|Bacteria	M	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SYD2_k127_6266742_4	1382359.JIAL01000001_gene1574	5.635e-52	207.0	COG0706@1|root,COG0706@2|Bacteria,3Y3TD@57723|Acidobacteria,2JI2B@204432|Acidobacteriia	204432|Acidobacteriia	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
SYD2_k127_6266742_3	1267533.KB906733_gene2908	5.728e-67	235.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SYD2_k127_6266742_10	153721.MYP_4620	8.349e-09	65.0	2EKCZ@1|root,33E39@2|Bacteria,4NXWT@976|Bacteroidetes,47VYQ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6266742_1	929562.Emtol_0970	2.48e-178	574.0	COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,47JSS@768503|Cytophagia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SYD2_k127_6266742_5	1122915.AUGY01000099_gene3654	1.595e-48	180.0	COG2318@1|root,COG2318@2|Bacteria,1V6MV@1239|Firmicutes,4HH68@91061|Bacilli,26YC6@186822|Paenibacillaceae	91061|Bacilli	S	Squalene--hopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SYD2_k127_6301911_6	1267533.KB906738_gene2407	8.788e-56	199.0	2FCTA@1|root,344W8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6301911_0	460265.Mnod_3490	2.56e-153	490.0	COG0535@1|root,COG0535@2|Bacteria,1PKRS@1224|Proteobacteria,2UZDC@28211|Alphaproteobacteria,1JU6F@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SYD2_k127_6301911_2	1267533.KB906733_gene3157	1.423e-69	243.0	COG4798@1|root,COG4798@2|Bacteria,3Y5JR@57723|Acidobacteria,2JK45@204432|Acidobacteriia	204432|Acidobacteriia	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
SYD2_k127_6301911_4	682795.AciX8_0250	7.633e-67	235.0	COG0463@1|root,COG0463@2|Bacteria,3Y63N@57723|Acidobacteria,2JKM7@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SYD2_k127_6301911_1	1267534.KB906756_gene56	8.765e-89	309.0	COG1216@1|root,COG1216@2|Bacteria,3Y6HJ@57723|Acidobacteria,2JK7H@204432|Acidobacteriia	204432|Acidobacteriia	S	Pfam:DUF2029	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SYD2_k127_6301911_3	926566.Terro_1690	4.012e-67	241.0	COG3222@1|root,COG3222@2|Bacteria,3Y5T4@57723|Acidobacteria,2JKE7@204432|Acidobacteriia	204432|Acidobacteriia	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
SYD2_k127_6301911_9	997346.HMPREF9374_1899	1.672e-25	119.0	COG0701@1|root,COG0701@2|Bacteria,1TQC7@1239|Firmicutes,4HDIZ@91061|Bacilli	91061|Bacilli	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
SYD2_k127_6301911_8	1123278.KB893580_gene892	1.835e-39	158.0	COG0500@1|root,COG2226@2|Bacteria,4NIN6@976|Bacteroidetes,47JAJ@768503|Cytophagia	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
SYD2_k127_6301911_5	1242864.D187_010314	6.544e-61	213.0	COG2128@1|root,COG2128@2|Bacteria,1RD1K@1224|Proteobacteria,42ZTP@68525|delta/epsilon subdivisions,2WV97@28221|Deltaproteobacteria,2YWVF@29|Myxococcales	28221|Deltaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SYD2_k127_6301911_7	1267533.KB906733_gene3126	6.031e-53	189.0	COG1917@1|root,COG1917@2|Bacteria,3Y4Y3@57723|Acidobacteria,2JMS3@204432|Acidobacteriia	204432|Acidobacteriia	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SYD2_k127_632296_1	234267.Acid_4205	2.038e-74	257.0	COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria	57723|Acidobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
SYD2_k127_632296_0	945713.IALB_2426	2.815e-87	296.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	fdnH	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3,Fer4_4
SYD2_k127_632296_3	1191523.MROS_1567	4.455e-22	105.0	COG0509@1|root,COG2204@1|root,COG0509@2|Bacteria,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GAF_2,GCV_H,Response_reg
SYD2_k127_632296_2	335543.Sfum_2805	5.068e-33	138.0	COG0509@1|root,COG0509@2|Bacteria,1Q1KI@1224|Proteobacteria,437BG@68525|delta/epsilon subdivisions,2X2GI@28221|Deltaproteobacteria,2MRJR@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
SYD2_k127_632296_4	1134912.AJTV01000024_gene2803	2.688e-11	73.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,2U31V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6340659_1	234267.Acid_2646	5.122e-65	230.0	COG2834@1|root,COG2834@2|Bacteria,3Y7NW@57723|Acidobacteria	57723|Acidobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6340659_0	335543.Sfum_3330	6.35e-129	423.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,42MSY@68525|delta/epsilon subdivisions,2WJXR@28221|Deltaproteobacteria,2MQS7@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SYD2_k127_6340659_4	204669.Acid345_2970	2.53e-24	108.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
SYD2_k127_6340659_5	1232410.KI421422_gene2100	2.393e-21	95.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,42VWR@68525|delta/epsilon subdivisions,2WS4U@28221|Deltaproteobacteria,43VU0@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
SYD2_k127_6340659_2	671143.DAMO_1931	5.33e-57	216.0	COG1538@1|root,COG1538@2|Bacteria,2NPKK@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SYD2_k127_6340659_3	671143.DAMO_1932	2.389e-35	143.0	COG0845@1|root,COG0845@2|Bacteria,2NPS3@2323|unclassified Bacteria	2|Bacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
SYD2_k127_6364495_3	204669.Acid345_3429	7.358e-76	259.0	COG1793@1|root,COG1793@2|Bacteria,3Y45N@57723|Acidobacteria,2JIH0@204432|Acidobacteriia	204432|Acidobacteriia	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SYD2_k127_6364495_1	234267.Acid_5076	1.65e-136	442.0	COG3285@1|root,COG3285@2|Bacteria,3Y74I@57723|Acidobacteria	57723|Acidobacteria	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SYD2_k127_6364495_0	748280.NH8B_2766	0.0	1659.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2VI8X@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SYD2_k127_6364495_7	357808.RoseRS_3612	1.837e-22	104.0	COG2199@1|root,COG3706@2|Bacteria,2GAEA@200795|Chloroflexi,375RZ@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SYD2_k127_6364495_9	882.DVU_2434	6.764e-07	55.0	2E6J8@1|root,3316B@2|Bacteria,1N7GY@1224|Proteobacteria,42V6W@68525|delta/epsilon subdivisions,2WRHG@28221|Deltaproteobacteria,2MC8I@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6364495_6	335543.Sfum_0084	9.643e-29	120.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MS96@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SYD2_k127_6364495_8	56780.SYN_01756	1.517e-14	86.0	COG4726@1|root,COG4726@2|Bacteria,1NK1B@1224|Proteobacteria	1224|Proteobacteria	NU	Pilus assembly protein PilX	-	-	-	ko:K02673	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilX_N
SYD2_k127_6364495_2	871963.Desdi_2783	4.96e-125	411.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,248U7@186801|Clostridia,261AX@186807|Peptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SYD2_k127_6364495_5	742725.HMPREF9450_01123	1.458e-46	170.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,2FT3J@200643|Bacteroidia,22UFP@171550|Rikenellaceae	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SYD2_k127_6364495_4	1295642.H839_12659	4.366e-63	221.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,4HA7P@91061|Bacilli,1WEUJ@129337|Geobacillus	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SYD2_k127_6399119_0	1172181.KB911721_gene3844	1.066e-67	244.0	COG0654@1|root,COG0654@2|Bacteria,2GKUZ@201174|Actinobacteria	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SYD2_k127_6399119_1	1172181.KB911721_gene3844	1.291e-42	162.0	COG0654@1|root,COG0654@2|Bacteria,2GKUZ@201174|Actinobacteria	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SYD2_k127_6399119_2	1192034.CAP_2018	0.0002646	46.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SYD2_k127_6428261_4	497965.Cyan7822_0753	1.46e-21	96.0	COG2026@1|root,COG2026@2|Bacteria,1GMIK@1117|Cyanobacteria,3KKFI@43988|Cyanothece	1117|Cyanobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SYD2_k127_6428261_3	1340493.JNIF01000003_gene1773	5.716e-49	181.0	COG1143@1|root,COG1143@2|Bacteria,3Y371@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
SYD2_k127_6428261_5	391038.Bphy_4140	1.973e-06	58.0	2BGXF@1|root,32AXE@2|Bacteria,1PXHQ@1224|Proteobacteria,2WCXJ@28216|Betaproteobacteria,1K8P8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SYD2_k127_6428261_2	1232410.KI421424_gene1665	1.033e-50	184.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2WP3R@28221|Deltaproteobacteria,43SGP@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	NDK	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SYD2_k127_6428261_0	1267534.KB906754_gene3139	1.154e-132	428.0	COG0074@1|root,COG0074@2|Bacteria,3Y3UX@57723|Acidobacteria,2JHSN@204432|Acidobacteriia	204432|Acidobacteriia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SYD2_k127_6428261_1	661478.OP10G_2763	4.46e-111	371.0	COG1236@1|root,COG1236@2|Bacteria	2|Bacteria	J	nucleic acid phosphodiester bond hydrolysis	-	-	-	ko:K07576,ko:K07577	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
SYD2_k127_6441999_2	1121472.AQWN01000007_gene1067	9.111e-42	160.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,261UB@186807|Peptococcaceae	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
SYD2_k127_6441999_1	316274.Haur_4101	1.398e-58	223.0	COG5530@1|root,COG5530@2|Bacteria	2|Bacteria	S	Predicted integral membrane protein (DUF2270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2270
SYD2_k127_6441999_0	1382359.JIAL01000001_gene2082	4.032e-190	606.0	COG2986@1|root,COG2986@2|Bacteria,3Y3YW@57723|Acidobacteria,2JIK6@204432|Acidobacteriia	204432|Acidobacteriia	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SYD2_k127_6441999_3	1382306.JNIM01000001_gene3396	2.869e-41	153.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SYD2_k127_6458085_1	526218.Sterm_3511	2.942e-31	126.0	2E3YR@1|root,32YVP@2|Bacteria	2|Bacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SYD2_k127_6458085_2	266748.HY04_05035	2.976e-27	117.0	COG0457@1|root,COG0457@2|Bacteria,4NSXM@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
SYD2_k127_6458085_0	761193.Runsl_2173	8.57e-106	351.0	COG1284@1|root,COG1284@2|Bacteria,4NG9F@976|Bacteroidetes,47JNV@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
SYD2_k127_6474204_2	215803.DB30_7179	4.798e-118	390.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,42YQP@68525|delta/epsilon subdivisions,2WTJM@28221|Deltaproteobacteria,2YY5X@29|Myxococcales	28221|Deltaproteobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SYD2_k127_6474204_9	1229204.AMYY01000013_gene212	1.394e-09	62.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2UFM1@28211|Alphaproteobacteria,4BQSB@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0033218,GO:0042277,GO:0043167,GO:0043168,GO:0043295,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0055114,GO:0072341,GO:1900750,GO:1901681	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
SYD2_k127_6474204_8	448385.sce3852	6.95e-11	72.0	COG0612@1|root,COG0741@1|root,COG0612@2|Bacteria,COG0741@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,2YURT@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
SYD2_k127_6474204_6	1267535.KB906767_gene4499	1.324e-52	192.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia	204432|Acidobacteriia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SYD2_k127_6474204_4	1267535.KB906767_gene1129	2.979e-69	260.0	COG0515@1|root,COG0515@2|Bacteria,3Y4IC@57723|Acidobacteria,2JJ7M@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SYD2_k127_6474204_11	756067.MicvaDRAFT_0143	1.317e-08	64.0	2F9ZD@1|root,3428I@2|Bacteria,1GEDG@1117|Cyanobacteria,1HFT2@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6474204_10	756067.MicvaDRAFT_0142	1.508e-09	65.0	2EIG2@1|root,33C7E@2|Bacteria,1GEUK@1117|Cyanobacteria,1HFRR@1150|Oscillatoriales	1117|Cyanobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
SYD2_k127_6474204_1	861299.J421_0736	2.713e-134	444.0	COG1228@1|root,COG1228@2|Bacteria,1ZTI7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SYD2_k127_6474204_0	861299.J421_0737	6.948e-177	567.0	COG1228@1|root,COG1228@2|Bacteria,1ZTC8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SYD2_k127_6474204_3	1227739.Hsw_2021	2.089e-94	334.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,47KE2@768503|Cytophagia	976|Bacteroidetes	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
SYD2_k127_6474204_5	1157490.EL26_19490	1.028e-59	217.0	COG0492@1|root,COG0492@2|Bacteria,1V4WN@1239|Firmicutes,4HHA8@91061|Bacilli,278DV@186823|Alicyclobacillaceae	91061|Bacilli	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SYD2_k127_6474204_7	368407.Memar_1326	4.334e-31	130.0	COG1073@1|root,arCOG01654@2157|Archaea	2157|Archaea	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	AXE1,Hydrolase_4
SYD2_k127_6485313_5	3218.PP1S46_300V6.1	5.039e-95	325.0	COG0667@1|root,2S0PI@2759|Eukaryota,37UGN@33090|Viridiplantae,3GP0T@35493|Streptophyta	35493|Streptophyta	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SYD2_k127_6485313_2	234267.Acid_3960	5.433e-170	542.0	COG0111@1|root,COG0111@2|Bacteria,3Y7TQ@57723|Acidobacteria	57723|Acidobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SYD2_k127_6485313_9	272123.Anacy_3334	8.697e-72	251.0	COG0300@1|root,COG0300@2|Bacteria,1G2JD@1117|Cyanobacteria,1HJWF@1161|Nostocales	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SYD2_k127_6485313_0	926566.Terro_0850	1.988e-289	908.0	COG1529@1|root,COG1529@2|Bacteria,3Y6BF@57723|Acidobacteria	57723|Acidobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SYD2_k127_6485313_16	1173264.KI913950_gene4469	8.341e-33	130.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6485313_19	278957.ABEA03000095_gene4585	4.721e-23	101.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SYD2_k127_6485313_11	1125863.JAFN01000001_gene1219	1.716e-47	177.0	COG2080@1|root,COG2080@2|Bacteria,1Q9C0@1224|Proteobacteria,42TB7@68525|delta/epsilon subdivisions,2WPGV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SYD2_k127_6485313_7	1267534.KB906759_gene1949	1.328e-85	292.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	1.17.1.4	ko:K13479	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SYD2_k127_6485313_18	1200792.AKYF01000010_gene2397	2.484e-24	116.0	2DKY8@1|root,30VAD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TIG
SYD2_k127_6485313_20	251221.35213153	5.127e-06	57.0	COG5523@1|root,COG5523@2|Bacteria,1G75W@1117|Cyanobacteria	1117|Cyanobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
SYD2_k127_6485313_21	331678.Cphamn1_2098	0.000241	51.0	COG5523@1|root,COG5523@2|Bacteria,1FEN5@1090|Chlorobi	1090|Chlorobi	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6485313_1	1254432.SCE1572_35000	1.164e-175	561.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,42RF2@68525|delta/epsilon subdivisions,2WP05@28221|Deltaproteobacteria,2YWCM@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	allB	-	3.5.2.5	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02425	RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SYD2_k127_6485313_3	448385.sce5877	3.913e-138	447.0	COG3195@1|root,COG4266@1|root,COG3195@2|Bacteria,COG4266@2|Bacteria,1MXJK@1224|Proteobacteria,42YE0@68525|delta/epsilon subdivisions,2X30N@28221|Deltaproteobacteria,2YTWS@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the allantoicase family	alc	-	3.5.3.4	ko:K01477	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02422	RC00379,RC00712	ko00000,ko00001,ko00002,ko01000	-	-	-	Allantoicase,OHCU_decarbox
SYD2_k127_6485313_13	861299.J421_2143	1.795e-43	164.0	COG3195@1|root,COG3195@2|Bacteria	2|Bacteria	S	allantoin biosynthetic process	uraD	-	3.5.3.4,4.1.1.97	ko:K01477,ko:K16840	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02422,R06604	RC00379,RC00712,RC01551	ko00000,ko00001,ko00002,ko01000	-	-	-	OHCU_decarbox
SYD2_k127_6485313_15	1242864.D187_001061	1.785e-33	133.0	COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,42W18@68525|delta/epsilon subdivisions,2X9WW@28221|Deltaproteobacteria,2YVN9@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	-	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
SYD2_k127_6485313_8	1198452.Jab_1c14580	3.697e-79	272.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,2VIC0@28216|Betaproteobacteria,473XM@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
SYD2_k127_6485313_12	926549.KI421517_gene500	1.279e-43	164.0	COG2947@1|root,COG2947@2|Bacteria,4NNQG@976|Bacteroidetes,47QAF@768503|Cytophagia	976|Bacteroidetes	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
SYD2_k127_6485313_10	194439.CT0662	6.208e-56	201.0	COG1225@1|root,COG1225@2|Bacteria,1FDZX@1090|Chlorobi	1090|Chlorobi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SYD2_k127_6485313_14	469383.Cwoe_3468	7.045e-34	135.0	COG4430@1|root,COG4430@2|Bacteria	2|Bacteria	F	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052,OmdA
SYD2_k127_6485313_4	246194.CHY_0060	1.316e-106	357.0	COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,24DU3@186801|Clostridia,42HHC@68295|Thermoanaerobacterales	186801|Clostridia	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K03319,ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47,2.A.47.1	-	-	Na_sulph_symp
SYD2_k127_6502259_2	1267535.KB906767_gene769	1.889e-130	432.0	COG1109@1|root,COG1109@2|Bacteria,3Y36F@57723|Acidobacteria,2JHU9@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SYD2_k127_6502259_10	1382356.JQMP01000004_gene611	2.81e-55	209.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi,27XRJ@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SYD2_k127_6502259_8	391625.PPSIR1_34013	8.213e-79	285.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1R45Z@1224|Proteobacteria,43AMH@68525|delta/epsilon subdivisions,2X61H@28221|Deltaproteobacteria,2Z38T@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,Guanylate_cyc
SYD2_k127_6502259_19	234267.Acid_3837	8.722e-21	107.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
SYD2_k127_6502259_20	204669.Acid345_2892	9.338e-15	88.0	COG4932@1|root,COG4932@2|Bacteria,3Y5W1@57723|Acidobacteria,2JNVI@204432|Acidobacteriia	204432|Acidobacteriia	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SYD2_k127_6502259_5	379066.GAU_0129	6.575e-114	383.0	COG0612@1|root,COG0612@2|Bacteria,1ZT1J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SYD2_k127_6502259_7	861299.J421_1261	1.486e-90	315.0	COG0612@1|root,COG0612@2|Bacteria,1ZT7N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16_C
SYD2_k127_6502259_0	198467.NP92_07845	3.73e-268	847.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,21VD1@150247|Anoxybacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32840	3HCDH,3HCDH_N,ECH_1
SYD2_k127_6502259_12	234267.Acid_5695	3.223e-39	147.0	COG0183@1|root,COG0183@2|Bacteria,3Y2U4@57723|Acidobacteria	57723|Acidobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
SYD2_k127_6502259_3	639030.JHVA01000001_gene3849	3.38e-116	380.0	COG0183@1|root,COG0183@2|Bacteria,3Y2U4@57723|Acidobacteria,2JIS1@204432|Acidobacteriia	204432|Acidobacteriia	I	Thiolase, C-terminal domain	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
SYD2_k127_6502259_17	383372.Rcas_2542	2.494e-28	120.0	2F76J@1|root,33ZMZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6502259_1	204669.Acid345_2471	2.89e-197	631.0	COG1960@1|root,COG1960@2|Bacteria,3Y2NA@57723|Acidobacteria,2JII2@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SYD2_k127_6502259_11	1121422.AUMW01000003_gene994	3.765e-53	200.0	COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,24BDQ@186801|Clostridia,261Z4@186807|Peptococcaceae	186801|Clostridia	S	Zn-dependent hydrolase, glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SYD2_k127_6502259_16	234267.Acid_5723	4.263e-32	139.0	COG0265@1|root,COG0265@2|Bacteria,3Y4AJ@57723|Acidobacteria	57723|Acidobacteria	O	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
SYD2_k127_6502259_9	237368.SCABRO_03208	1.895e-77	270.0	COG4301@1|root,COG4301@2|Bacteria,2IXEH@203682|Planctomycetes	203682|Planctomycetes	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
SYD2_k127_6502259_4	525897.Dbac_2296	2.48e-114	385.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WKVE@28221|Deltaproteobacteria,2M7ZJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Transporter-associated region	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SYD2_k127_6502259_13	204669.Acid345_0553	3.203e-38	149.0	COG1329@1|root,COG1329@2|Bacteria,3Y4ZG@57723|Acidobacteria,2JMXA@204432|Acidobacteriia	204432|Acidobacteriia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SYD2_k127_6502259_6	1144275.COCOR_00645	3.205e-93	325.0	COG4395@1|root,COG4395@2|Bacteria	2|Bacteria	S	Tim44	MA20_24770	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	Tim44
SYD2_k127_6502259_21	452662.SJA_C1-10370	4.884e-14	80.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2U5XG@28211|Alphaproteobacteria,2K470@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SYD2_k127_6502259_15	1340493.JNIF01000003_gene4350	1.396e-34	138.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria	57723|Acidobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SYD2_k127_6502259_14	1297742.A176_00518	4.848e-36	139.0	COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,42WXG@68525|delta/epsilon subdivisions,2WT19@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SYD2_k127_6502259_18	240015.ACP_2974	3.347e-26	112.0	COG2172@1|root,COG2172@2|Bacteria,3Y4TY@57723|Acidobacteria,2JJGJ@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SYD2_k127_6521316_1	86416.Clopa_2530	3.459e-67	238.0	COG1794@1|root,COG1794@2|Bacteria,1TR3U@1239|Firmicutes,24ADY@186801|Clostridia,36G2E@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS14520	Asp_Glu_race
SYD2_k127_6521316_2	1117379.BABA_22708	1.004e-28	126.0	COG4271@1|root,COG4271@2|Bacteria,1VGIA@1239|Firmicutes,4HQMR@91061|Bacilli,1ZF0U@1386|Bacillus	91061|Bacilli	K	Predicted nucleotide-binding protein containing TIR-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR-like
SYD2_k127_6521316_0	204669.Acid345_0490	2.743e-234	734.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3X0@57723|Acidobacteria,2JIZ1@204432|Acidobacteriia	204432|Acidobacteriia	EU	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SYD2_k127_6525519_1	1122599.AUGR01000014_gene587	1.178e-86	304.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1XHK6@135619|Oceanospirillales	1236|Gammaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SYD2_k127_6525519_3	1121413.JMKT01000001_gene1686	4.854e-45	169.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,42W70@68525|delta/epsilon subdivisions,2X245@28221|Deltaproteobacteria,2MFSC@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SYD2_k127_6525519_0	1267535.KB906767_gene2479	1.432e-91	321.0	COG0531@1|root,COG0531@2|Bacteria,3Y2T1@57723|Acidobacteria,2JI3B@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SYD2_k127_6525519_2	118163.Ple7327_2631	1.646e-73	259.0	COG2367@1|root,COG2367@2|Bacteria,1G0DG@1117|Cyanobacteria,3VI6T@52604|Pleurocapsales	1117|Cyanobacteria	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
SYD2_k127_6525519_4	1239962.C943_03946	8.315e-34	132.0	COG5285@1|root,COG5285@2|Bacteria,4NHQ6@976|Bacteroidetes,47NC5@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SYD2_k127_6544520_15	906888.JCM19314_1612	2.887e-10	70.0	COG0500@1|root,COG0500@2|Bacteria,4NFUU@976|Bacteroidetes,1I0M8@117743|Flavobacteriia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SYD2_k127_6544520_7	435591.BDI_3231	5.288e-40	164.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	capM	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SYD2_k127_6544520_14	483219.LILAB_26185	1.301e-11	76.0	COG0438@1|root,COG0438@2|Bacteria,1MWVX@1224|Proteobacteria,42WEG@68525|delta/epsilon subdivisions,2X7H6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SYD2_k127_6544520_13	479433.Caci_3232	3.19e-21	107.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycosyl transferase, group 1	-	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.11	ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SYD2_k127_6544520_5	118163.Ple7327_2126	7.535e-52	198.0	COG1216@1|root,COG1216@2|Bacteria,1G346@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SYD2_k127_6544520_6	443143.GM18_0952	1.063e-51	199.0	COG0438@1|root,COG0438@2|Bacteria,1MWVX@1224|Proteobacteria,42WEG@68525|delta/epsilon subdivisions,2WWQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
SYD2_k127_6544520_11	765420.OSCT_0015	3.355e-29	123.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
SYD2_k127_6544520_8	479434.Sthe_1712	9.754e-33	142.0	COG0859@1|root,COG0859@2|Bacteria,2G8MX@200795|Chloroflexi,27Y5X@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SYD2_k127_6544520_2	1173027.Mic7113_5754	6.008e-121	402.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,1H8CS@1150|Oscillatoriales	1117|Cyanobacteria	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
SYD2_k127_6544520_4	243231.GSU1507	7.779e-86	296.0	COG0859@1|root,COG0859@2|Bacteria,1RFBZ@1224|Proteobacteria,43AIS@68525|delta/epsilon subdivisions,2WV3S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
SYD2_k127_6544520_1	237368.SCABRO_01358	1.021e-130	424.0	COG1682@1|root,COG1682@2|Bacteria,2IYXC@203682|Planctomycetes	203682|Planctomycetes	U	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SYD2_k127_6544520_0	56110.Oscil6304_1714	4.025e-186	589.0	COG0399@1|root,COG0399@2|Bacteria,1G4PM@1117|Cyanobacteria,1HFC1@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM DegT DnrJ EryC1 StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SYD2_k127_6544520_3	682795.AciX8_1492	3.403e-99	356.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,3Y2V7@57723|Acidobacteria,2JIYH@204432|Acidobacteriia	57723|Acidobacteria	D	G-rich domain on putative tyrosine kinase	-	-	2.7.10.1	ko:K08252,ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,Wzz
SYD2_k127_6544520_12	1267535.KB906767_gene3494	6.773e-27	123.0	COG1596@1|root,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	wza	-	-	ko:K01991,ko:K20988	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SYD2_k127_6544520_9	204669.Acid345_4197	2.77e-30	138.0	28M4B@1|root,2ZAI9@2|Bacteria,3Y3NA@57723|Acidobacteria,2JI3J@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6544520_16	1244869.H261_05719	0.0007163	51.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,2JWST@204441|Rhodospirillales	204441|Rhodospirillales	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SYD2_k127_6544520_10	204669.Acid345_3344	2.325e-29	131.0	COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria,2JIK2@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3
SYD2_k127_6553467_2	1379698.RBG1_1C00001G0471	7.028e-192	606.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	ycbD	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SYD2_k127_6553467_0	1382359.JIAL01000001_gene807	5.052e-278	865.0	COG0481@1|root,COG0481@2|Bacteria,3Y3EX@57723|Acidobacteria,2JI4G@204432|Acidobacteriia	204432|Acidobacteriia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SYD2_k127_6553467_9	269797.Mbar_A2861	4.307e-73	256.0	arCOG06785@1|root,arCOG06785@2157|Archaea	269797.Mbar_A2861|-	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6553467_10	269797.Mbar_A2861	1.379e-67	243.0	arCOG06785@1|root,arCOG06785@2157|Archaea	269797.Mbar_A2861|-	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6553467_3	269797.Mbar_A2862	6.778e-172	591.0	COG2319@1|root,arCOG02561@2157|Archaea,2Y41K@28890|Euryarchaeota,2NAYQ@224756|Methanomicrobia	224756|Methanomicrobia	S	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
SYD2_k127_6553467_12	28072.Nos7524_5414	1.772e-64	235.0	COG1216@1|root,COG1216@2|Bacteria,1G3T8@1117|Cyanobacteria,1HNFR@1161|Nostocales	1117|Cyanobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
SYD2_k127_6553467_22	518766.Rmar_1585	8.403e-14	83.0	COG1493@1|root,COG1493@2|Bacteria,4P7YQ@976|Bacteroidetes	976|Bacteroidetes	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6553467_19	1499967.BAYZ01000030_gene1170	3.542e-36	151.0	COG0535@1|root,COG0535@2|Bacteria,2NRPX@2323|unclassified Bacteria	2|Bacteria	S	Radical SAM superfamily	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SYD2_k127_6553467_17	452637.Oter_4256	4.543e-39	159.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6553467_6	1380390.JIAT01000009_gene2235	7.416e-112	374.0	COG3055@1|root,COG3055@2|Bacteria,2HQPC@201174|Actinobacteria,4CSAN@84995|Rubrobacteria	84995|Rubrobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6553467_15	234267.Acid_4250	8.511e-45	179.0	COG0644@1|root,COG0644@2|Bacteria,3Y5JJ@57723|Acidobacteria	57723|Acidobacteria	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Pyr_redox_2
SYD2_k127_6553467_13	485916.Dtox_0324	4.291e-57	211.0	COG2078@1|root,COG3885@1|root,COG2078@2|Bacteria,COG3885@2|Bacteria,1TQH8@1239|Firmicutes,2491Q@186801|Clostridia,26152@186807|Peptococcaceae	186801|Clostridia	S	pfam ammecr1	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,LigB
SYD2_k127_6553467_14	891968.Anamo_0709	1.115e-45	177.0	COG2078@1|root,COG3885@1|root,COG2078@2|Bacteria,COG3885@2|Bacteria,3T9SI@508458|Synergistetes	508458|Synergistetes	S	dioxygenase class III protein subunit B	-	-	-	-	-	-	-	-	-	-	-	-	AMMECR1,LigB
SYD2_k127_6553467_5	945713.IALB_1883	3.166e-131	442.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
SYD2_k127_6553467_21	335543.Sfum_0084	1.192e-33	133.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MS96@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SYD2_k127_6553467_26	1499685.CCFJ01000056_gene178	0.0007193	49.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,4HHB5@91061|Bacilli,1ZGZE@1386|Bacillus	91061|Bacilli	NT	COG0835 Chemotaxis signal transduction protein	cheW	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009453,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0042333,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SYD2_k127_6553467_16	1121015.N789_04655	1.038e-41	155.0	COG0599@1|root,COG0599@2|Bacteria,1N38Z@1224|Proteobacteria,1S5G6@1236|Gammaproteobacteria,1X6C8@135614|Xanthomonadales	135614|Xanthomonadales	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SYD2_k127_6553467_1	247490.KSU1_C0443	2.266e-198	640.0	COG0526@1|root,COG3391@1|root,COG0526@2|Bacteria,COG3391@2|Bacteria,2IXWV@203682|Planctomycetes	203682|Planctomycetes	CO	PFAM NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,Thioredoxin_8
SYD2_k127_6553467_8	1234364.AMSF01000053_gene1294	2.513e-86	288.0	COG2193@1|root,COG2193@2|Bacteria,1RAQ8@1224|Proteobacteria,1S2G2@1236|Gammaproteobacteria,1X60R@135614|Xanthomonadales	135614|Xanthomonadales	P	Bacterioferritin (cytochrome b1)	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SYD2_k127_6553467_18	1484479.DI14_03780	3.609e-37	152.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,3WFI8@539002|Bacillales incertae sedis	91061|Bacilli	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,TPR_2,TPR_8
SYD2_k127_6553467_7	316274.Haur_1203	5.994e-102	339.0	COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi	200795|Chloroflexi	C	3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SYD2_k127_6553467_4	204669.Acid345_3484	4.086e-146	470.0	COG0823@1|root,COG0823@2|Bacteria,3Y36H@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SYD2_k127_6553467_11	220341.16503194	1.325e-65	231.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,3ZJX4@590|Salmonella	1236|Gammaproteobacteria	E	AAA domain	yecC	GO:0000099,GO:0000101,GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0097159,GO:0097367,GO:0098656,GO:1901265,GO:1901363,GO:1901682,GO:1902475,GO:1903825,GO:1905039	3.6.3.21	ko:K02028,ko:K02029,ko:K10004,ko:K10010,ko:K10038	ko02010,ko02020,map02010,map02020	M00227,M00230,M00234,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.10,3.A.1.3.14,3.A.1.3.19,3.A.1.3.2,3.A.1.3.4	-	-	ABC_tran
SYD2_k127_6553467_20	247490.KSU1_D0644	9.018e-36	140.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,2IY5R@203682|Planctomycetes	203682|Planctomycetes	P	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
SYD2_k127_6614359_2	1121373.KB903623_gene2360	2.826e-73	250.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,47NNF@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
SYD2_k127_6614359_6	653733.Selin_0887	3.405e-50	183.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	nuoE	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SYD2_k127_6614359_0	443143.GM18_4387	7.237e-152	490.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00333,ko:K13378,ko:K13380	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
SYD2_k127_6614359_7	247490.KSU1_D0327	1.626e-42	161.0	COG0852@1|root,COG0852@2|Bacteria,2IZCK@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SYD2_k127_6614359_4	671143.DAMO_1605	1.861e-71	248.0	COG0377@1|root,COG0377@2|Bacteria,2NP84@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SYD2_k127_6614359_8	639030.JHVA01000001_gene765	1.148e-35	140.0	COG0838@1|root,COG0838@2|Bacteria,3Y4SD@57723|Acidobacteria,2JJ78@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SYD2_k127_6614359_11	1121920.AUAU01000025_gene2317	4.069e-18	93.0	2ET40@1|root,33KN7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6614359_13	204669.Acid345_1317	3.623e-14	74.0	COG2104@1|root,COG2104@2|Bacteria,3Y5XU@57723|Acidobacteria,2JK4P@204432|Acidobacteriia	204432|Acidobacteriia	H	thiamine biosynthesis protein ThiS	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SYD2_k127_6614359_1	234267.Acid_7731	6.68e-100	332.0	COG2022@1|root,COG2022@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
SYD2_k127_6614359_5	366649.XFF4834R_chr42170	1.535e-54	222.0	COG2931@1|root,COG3468@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3468@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria,1T45Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Domains in Na-Ca exchangers and integrin-beta4	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
SYD2_k127_6614359_10	1121930.AQXG01000001_gene1125	7.01e-23	117.0	COG0737@1|root,COG1506@1|root,COG0737@2|Bacteria,COG1506@2|Bacteria,4NQQD@976|Bacteroidetes	976|Bacteroidetes	E	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,LTD
SYD2_k127_6614359_9	493475.GARC_4550	7.27e-26	127.0	COG1506@1|root,COG2374@1|root,COG1506@2|Bacteria,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RMHH@1236|Gammaproteobacteria,46500@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Extracellular nuclease	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_5,Endonuclease_1,Exo_endo_phos,LTD
SYD2_k127_6614359_14	357808.RoseRS_0010	1.283e-12	83.0	COG0823@1|root,COG0823@2|Bacteria,2G8T5@200795|Chloroflexi,376FH@32061|Chloroflexia	32061|Chloroflexia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SYD2_k127_6614359_3	671143.DAMO_2354	1.696e-72	251.0	COG1090@1|root,COG1090@2|Bacteria,2NPHC@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
SYD2_k127_6617389_1	234267.Acid_2675	1.64e-23	107.0	COG1943@1|root,COG1943@2|Bacteria,3Y8QI@57723|Acidobacteria	57723|Acidobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SYD2_k127_6617389_0	1125863.JAFN01000001_gene2068	2.838e-145	476.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SYD2_k127_663692_6	1340493.JNIF01000004_gene288	4.333e-22	105.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20951	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	PQQ_2
SYD2_k127_663692_5	290402.Cbei_1251	7.003e-28	117.0	COG1671@1|root,COG1671@2|Bacteria,1VC3V@1239|Firmicutes,24N3K@186801|Clostridia,36MDT@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0178 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_663692_3	1121468.AUBR01000022_gene2771	2.005e-37	153.0	COG2199@1|root,COG3706@2|Bacteria,1VADD@1239|Firmicutes,25E7Q@186801|Clostridia,42J5P@68295|Thermoanaerobacterales	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	2.7.7.65	ko:K21022	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,PAS_9,Response_reg,TPR_8
SYD2_k127_663692_2	204669.Acid345_0559	1.708e-47	194.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,LolA_like,MacB_PCD
SYD2_k127_663692_7	1122169.AREN01000044_gene2480	2.959e-07	56.0	COG1943@1|root,COG1943@2|Bacteria,1QC63@1224|Proteobacteria,1T7V3@1236|Gammaproteobacteria,1JFWA@118969|Legionellales	118969|Legionellales	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SYD2_k127_663692_4	247490.KSU1_D0595	2.986e-30	137.0	COG0265@1|root,COG0265@2|Bacteria,2J23K@203682|Planctomycetes	203682|Planctomycetes	OT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trypsin_2
SYD2_k127_6710780_0	234267.Acid_1288	7.993e-137	451.0	COG0260@1|root,COG0260@2|Bacteria,3Y33T@57723|Acidobacteria	57723|Acidobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SYD2_k127_6710780_1	649747.HMPREF0083_00815	1.597e-46	171.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,26QAJ@186822|Paenibacillaceae	91061|Bacilli	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SYD2_k127_6710780_3	748449.Halha_0804	1.977e-05	57.0	COG1807@1|root,COG1807@2|Bacteria,1TR0R@1239|Firmicutes	1239|Firmicutes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SYD2_k127_6710780_2	204669.Acid345_2140	1.519e-15	77.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,3Y466@57723|Acidobacteria,2JHTM@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SYD2_k127_6723474_1	338966.Ppro_2406	4.962e-107	364.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,43TW2@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SYD2_k127_6723474_9	1121957.ATVL01000011_gene3642	6.221e-05	53.0	2EV2W@1|root,33NHX@2|Bacteria,4P93M@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2939
SYD2_k127_6723474_6	1192034.CAP_7617	5.617e-17	84.0	COG1722@1|root,COG1722@2|Bacteria,1Q1MN@1224|Proteobacteria,437C8@68525|delta/epsilon subdivisions,2X2HR@28221|Deltaproteobacteria,2YW46@29|Myxococcales	28221|Deltaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SYD2_k127_6723474_4	1267535.KB906767_gene4165	7.094e-74	259.0	COG0142@1|root,COG0142@2|Bacteria,3Y2HS@57723|Acidobacteria,2JIPK@204432|Acidobacteriia	204432|Acidobacteriia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SYD2_k127_6723474_0	1356852.N008_05325	1.762e-121	426.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NK8Q@976|Bacteroidetes,47KVN@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
SYD2_k127_6723474_5	945713.IALB_2758	1.434e-62	222.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SYD2_k127_6723474_7	1123508.JH636440_gene2493	2.648e-10	72.0	COG2165@1|root,COG2165@2|Bacteria,2J2WE@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
SYD2_k127_6723474_8	1267534.KB906759_gene1694	2.355e-08	62.0	COG3157@1|root,COG3157@2|Bacteria,3Y8DQ@57723|Acidobacteria,2JNKR@204432|Acidobacteriia	204432|Acidobacteriia	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
SYD2_k127_6723474_2	211165.AJLN01000063_gene3769	1.205e-101	339.0	COG0037@1|root,COG0037@2|Bacteria,1G2S7@1117|Cyanobacteria,1JM03@1189|Stigonemataceae	1117|Cyanobacteria	D	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	-	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
SYD2_k127_6736007_3	700598.Niako_2102	4.147e-31	128.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	pocR	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,PocR,Response_reg,Sigma54_activ_2
SYD2_k127_6736007_4	1502770.JQMG01000001_gene664	9.388e-17	91.0	2BWMX@1|root,2ZIUW@2|Bacteria,1RKH7@1224|Proteobacteria,2W84Y@28216|Betaproteobacteria,2KNYP@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6736007_0	1521187.JPIM01000022_gene637	1.133e-112	368.0	COG4422@1|root,COG4422@2|Bacteria,2G7TP@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
SYD2_k127_6736007_2	1121013.P873_12075	4.996e-61	219.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SYD2_k127_6736007_1	671143.DAMO_2848	7.79e-111	362.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2NNX4@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027	CBS,IMPDH,NMO
SYD2_k127_6746666_0	240016.ABIZ01000001_gene2828	5.524e-310	962.0	COG0422@1|root,COG0422@2|Bacteria,46S5R@74201|Verrucomicrobia,2ITWP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	ThiC-associated domain	-	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
SYD2_k127_6746666_1	234267.Acid_3724	1.193e-194	622.0	COG2234@1|root,COG2234@2|Bacteria,3Y4CJ@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SYD2_k127_6770670_0	234267.Acid_4698	7.517e-171	557.0	COG0405@1|root,COG0405@2|Bacteria,3Y6KV@57723|Acidobacteria	57723|Acidobacteria	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SYD2_k127_6770670_4	561175.KB894093_gene3822	0.0001992	49.0	2EGCD@1|root,33A46@2|Bacteria,2I140@201174|Actinobacteria,4EKRB@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
SYD2_k127_6770670_2	118166.JH976537_gene2787	2.517e-114	375.0	COG0053@1|root,COG0053@2|Bacteria,1G361@1117|Cyanobacteria,1HE5W@1150|Oscillatoriales	1117|Cyanobacteria	P	TIGRFAM cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SYD2_k127_6770670_1	404589.Anae109_0332	6.872e-168	546.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria	1224|Proteobacteria	S	oligopeptide transporter	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SYD2_k127_6770670_3	391625.PPSIR1_26798	6.901e-31	131.0	2E0EH@1|root,2ZZNI@2|Bacteria,1Q8YZ@1224|Proteobacteria,438YN@68525|delta/epsilon subdivisions,2X441@28221|Deltaproteobacteria,2YY76@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6816903_1	204669.Acid345_3772	5.867e-15	80.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SYD2_k127_6816903_0	1047013.AQSP01000115_gene361	3.88e-120	402.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SYD2_k127_6819948_0	518766.Rmar_2202	1.278e-191	612.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1FJSN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IQ	AMP-binding enzyme C-terminal domain	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SYD2_k127_6819948_1	926550.CLDAP_32500	1.444e-79	278.0	COG0026@1|root,COG0026@2|Bacteria,2G7GU@200795|Chloroflexi	200795|Chloroflexi	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6853093_0	671143.DAMO_0621	0.0	1419.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	Glyco_hydro_63
SYD2_k127_6853093_1	63737.Npun_F2216	1.439e-92	310.0	COG2258@1|root,COG2258@2|Bacteria,1G4BR@1117|Cyanobacteria,1HQ1K@1161|Nostocales	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
SYD2_k127_6899035_7	1128421.JAGA01000004_gene2593	1.951e-38	148.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	ycbD	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SYD2_k127_6899035_5	1340493.JNIF01000004_gene523	6.258e-85	301.0	COG0265@1|root,COG0265@2|Bacteria,3Y2SD@57723|Acidobacteria	57723|Acidobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SYD2_k127_6899035_4	240292.Ava_3336	6.059e-96	325.0	COG1063@1|root,COG1063@2|Bacteria,1FZZE@1117|Cyanobacteria,1HJXK@1161|Nostocales	1117|Cyanobacteria	E	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,Shikimate_DH
SYD2_k127_6899035_9	1254432.SCE1572_22585	1.453e-09	63.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K00406,ko:K03889	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00151,M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
SYD2_k127_6899035_0	1232410.KI421413_gene539	4.279e-173	555.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43RZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Glutamine amidotransferases class-II	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SYD2_k127_6899035_2	1120985.AUMI01000011_gene435	1.803e-141	458.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4H26T@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SYD2_k127_6899035_1	1499967.BAYZ01000095_gene4135	1.08e-159	515.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SYD2_k127_6899035_8	671143.DAMO_2422	5.517e-31	130.0	28VTP@1|root,2ZHVD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6899035_6	309801.trd_0178	1.458e-82	282.0	COG0483@1|root,COG0483@2|Bacteria,2G6JD@200795|Chloroflexi,27Y5G@189775|Thermomicrobia	189775|Thermomicrobia	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SYD2_k127_6899035_3	234267.Acid_7916	4.124e-135	454.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	234267.Acid_7916|-	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SYD2_k127_6933837_5	1237149.C900_00073	7.173e-37	149.0	COG0457@1|root,COG0457@2|Bacteria	1237149.C900_00073|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6933837_9	273121.WS1822	1.763e-05	53.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,42VD3@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	SMART Transport-associated and nodulation region	osmY_2	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
SYD2_k127_6933837_10	1038862.KB893862_gene2490	2.869e-05	48.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2UF5Q@28211|Alphaproteobacteria,3K05I@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
SYD2_k127_6933837_7	1246626.BleG1_3504	1.289e-12	68.0	2EFZF@1|root,339RM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6933837_4	1167006.UWK_00794	3.166e-43	170.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2MIAI@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SYD2_k127_6933837_3	1265313.HRUBRA_00129	3.738e-46	179.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,1J5PS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019899,GO:0022613,GO:0032296,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SYD2_k127_6933837_2	204669.Acid345_3450	9.639e-57	219.0	COG0768@1|root,COG0768@2|Bacteria,3Y3EP@57723|Acidobacteria,2JI45@204432|Acidobacteriia	204432|Acidobacteriia	M	penicillin-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Transpeptidase
SYD2_k127_6933837_1	671143.DAMO_2838	1.062e-63	237.0	COG4191@1|root,COG4191@2|Bacteria,2NQ9P@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SYD2_k127_6933837_0	1499967.BAYZ01000195_gene3085	3.65e-129	426.0	COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SYD2_k127_6933837_6	1340434.AXVA01000003_gene1655	1.722e-22	109.0	COG1196@1|root,COG1196@2|Bacteria,1UIE6@1239|Firmicutes,4IT31@91061|Bacilli,1ZS8R@1386|Bacillus	91061|Bacilli	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SYD2_k127_6933837_8	1158292.JPOE01000002_gene2600	1.99e-11	73.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2VKKI@28216|Betaproteobacteria,1KN6V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
SYD2_k127_6935756_3	926550.CLDAP_40310	6.303e-25	115.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K16703	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SYD2_k127_6935756_2	1169143.KB911034_gene1352	4.497e-35	150.0	COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,2VZJN@28216|Betaproteobacteria,1K5QS@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SYD2_k127_6935756_0	435591.BDI_3229	4.083e-56	206.0	COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
SYD2_k127_6935756_1	56110.Oscil6304_1713	2.822e-47	182.0	COG5653@1|root,COG5653@2|Bacteria,1GC7U@1117|Cyanobacteria,1HEMP@1150|Oscillatoriales	1117|Cyanobacteria	M	FemAB family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SYD2_k127_6980668_1	1174528.JH992898_gene5032	3.255e-15	77.0	COG1943@1|root,COG1943@2|Bacteria,1GDMX@1117|Cyanobacteria,1JM0V@1189|Stigonemataceae	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SYD2_k127_6980668_3	1120936.KB907218_gene3442	4.28e-05	51.0	COG5662@1|root,COG5662@2|Bacteria,2I10N@201174|Actinobacteria,4EJDH@85012|Streptosporangiales	201174|Actinobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SYD2_k127_6980668_0	204669.Acid345_4448	3.667e-24	114.0	COG1595@1|root,COG1595@2|Bacteria,3Y7TB@57723|Acidobacteria,2JMZD@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
SYD2_k127_6980668_2	1403313.AXBR01000014_gene2203	5.859e-07	51.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli,1ZJWT@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6986484_10	278963.ATWD01000002_gene581	2.281e-60	213.0	COG0336@1|root,COG0336@2|Bacteria,3Y3CS@57723|Acidobacteria,2JHUJ@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SYD2_k127_6986484_13	1267535.KB906767_gene3057	1.778e-26	115.0	COG0806@1|root,COG0806@2|Bacteria,3Y51G@57723|Acidobacteria	57723|Acidobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SYD2_k127_6986484_15	1123371.ATXH01000031_gene2168	7.389e-17	84.0	COG1837@1|root,COG1837@2|Bacteria,2GI1Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SYD2_k127_6986484_14	1121405.dsmv_2129	4.721e-23	101.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,42V30@68525|delta/epsilon subdivisions,2WRH7@28221|Deltaproteobacteria,2MKIH@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SYD2_k127_6986484_1	1340493.JNIF01000003_gene3701	5.931e-155	503.0	COG0541@1|root,COG0541@2|Bacteria,3Y3AU@57723|Acidobacteria	57723|Acidobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SYD2_k127_6986484_5	518766.Rmar_2028	7.657e-104	374.0	COG0457@1|root,COG3829@1|root,COG0457@2|Bacteria,COG3829@2|Bacteria,4PM5Y@976|Bacteroidetes,1FIME@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
SYD2_k127_6986484_4	1183438.GKIL_2517	2.061e-128	422.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SYD2_k127_6986484_6	1183438.GKIL_2518	1.433e-101	335.0	COG1136@1|root,COG1136@2|Bacteria,1G17D@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SYD2_k127_6986484_7	1174528.JH992898_gene771	7.377e-91	315.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
SYD2_k127_6986484_0	1183438.GKIL_4354	9.431e-210	679.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SYD2_k127_6986484_19	1340493.JNIF01000003_gene1706	0.0004641	51.0	COG3166@1|root,COG3166@2|Bacteria,3Y4GJ@57723|Acidobacteria	57723|Acidobacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
SYD2_k127_6986484_18	715226.ABI_47530	0.000164	53.0	COG1413@1|root,COG1413@2|Bacteria,1NIYM@1224|Proteobacteria,2U11U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6986484_17	1538295.JY96_07815	0.0001392	51.0	COG2165@1|root,COG2165@2|Bacteria,1MZ5I@1224|Proteobacteria,2VU7P@28216|Betaproteobacteria,1KMIP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Type II secretory pathway, pseudopilin	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_6986484_11	404380.Gbem_3322	1.369e-45	171.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2WQNR@28221|Deltaproteobacteria,43W09@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	SpoU rRNA Methylase family	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SYD2_k127_6986484_12	338969.Rfer_2471	1.4e-41	161.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2VSR5@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SYD2_k127_6986484_3	204669.Acid345_0689	1.825e-131	432.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SYD2_k127_6986484_16	879212.DespoDRAFT_02588	4.737e-06	57.0	COG0784@1|root,COG0784@2|Bacteria,1RHWK@1224|Proteobacteria,42SCZ@68525|delta/epsilon subdivisions,2WPGH@28221|Deltaproteobacteria,2MK6H@213118|Desulfobacterales	28221|Deltaproteobacteria	T	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
SYD2_k127_6986484_8	234267.Acid_1024	5.848e-82	284.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	luxD	-	3.2.1.4,4.2.99.18	ko:K01179,ko:K06889,ko:K10773,ko:K15853	ko00500,ko01100,ko02020,ko02024,ko03410,map00500,map01100,map02020,map02024,map03410	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko03400	-	GH5,GH9	-	Abhydrolase_1,Acyl_transf_2,DLH,DUF2048,Hydrolase_4,Peptidase_S9
SYD2_k127_6986484_9	316274.Haur_0259	4.979e-67	241.0	COG1613@1|root,COG1613@2|Bacteria	2|Bacteria	P	Sulfate ABC transporter periplasmic sulfate-binding protein	subI	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iJN678.sbpA	SBP_bac_11
SYD2_k127_704449_2	234267.Acid_2103	5.094e-133	430.0	COG2382@1|root,COG2382@2|Bacteria,3Y2ZN@57723|Acidobacteria	2|Bacteria	GP	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,Glyco_hydro_10
SYD2_k127_704449_5	1173026.Glo7428_2145	6.497e-29	136.0	COG2730@1|root,COG2730@2|Bacteria,1G7EB@1117|Cyanobacteria	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
SYD2_k127_704449_0	714943.Mucpa_3835	5.435e-218	709.0	COG3534@1|root,COG3534@2|Bacteria,4NH8M@976|Bacteroidetes,1IVFD@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C
SYD2_k127_704449_1	755731.Clo1100_2297	1.591e-161	555.0	COG3507@1|root,COG3507@2|Bacteria,1TSKZ@1239|Firmicutes,24BRZ@186801|Clostridia,36F6C@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.55	ko:K15921	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43	-	CBM_6,Dockerin_1,Glyco_hydro_43
SYD2_k127_704449_4	1410632.JHWW01000004_gene1698	1.29e-44	188.0	COG5520@1|root,COG5520@2|Bacteria,1VV8A@1239|Firmicutes,250MI@186801|Clostridia	186801|Clostridia	M	Glycosyl hydrolase family 30 beta sandwich domain	-	-	3.2.1.136	ko:K15924	-	-	-	-	ko00000,ko01000	-	GH5	-	Glyco_hydro_30,Glyco_hydro_30C
SYD2_k127_704449_3	497964.CfE428DRAFT_1818	1.286e-47	198.0	COG2730@1|root,COG3533@1|root,COG4733@1|root,COG2730@2|Bacteria,COG3533@2|Bacteria,COG4733@2|Bacteria,46UYJ@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Ricin-type beta-trefoil lectin domain	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase,DUF1349,F5_F8_type_C,RicinB_lectin_2
SYD2_k127_7075942_13	1150626.PHAMO_210220	5.603e-16	78.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQMB@28211|Alphaproteobacteria,2JR7S@204441|Rhodospirillales	204441|Rhodospirillales	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SYD2_k127_7075942_5	1157490.EL26_07795	1.317e-74	261.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,2788K@186823|Alicyclobacillaceae	91061|Bacilli	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SYD2_k127_7075942_9	351627.Csac_1754	9.58e-35	144.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,42FBX@68295|Thermoanaerobacterales	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SYD2_k127_7075942_8	1117647.M5M_13675	6.958e-39	154.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1J5UQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SYD2_k127_7075942_14	1123065.ATWL01000004_gene2898	1.224e-06	55.0	2DRD4@1|root,33B9X@2|Bacteria,2GTDE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7075942_3	323259.Mhun_0648	3.98e-102	348.0	COG0614@1|root,COG1404@1|root,arCOG00702@2157|Archaea,arCOG03611@2157|Archaea,2XUT1@28890|Euryarchaeota,2NBHB@224756|Methanomicrobia	28890|Euryarchaeota	O	Subtilase family	hly	GO:0005575,GO:0005576	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8,TAT_signal
SYD2_k127_7075942_12	204669.Acid345_4769	4.537e-16	87.0	COG1579@1|root,COG1579@2|Bacteria,3Y509@57723|Acidobacteria,2JK0Q@204432|Acidobacteriia	204432|Acidobacteriia	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SYD2_k127_7075942_16	269084.syc1967_c	0.0009721	46.0	COG1645@1|root,COG1645@2|Bacteria,1GHBI@1117|Cyanobacteria,1H42I@1129|Synechococcus	1117|Cyanobacteria	S	bacterial-type flagellum-dependent swarming motility	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7075942_11	1128421.JAGA01000003_gene2880	3.445e-22	99.0	2ASAK@1|root,31HPU@2|Bacteria,2NQ6K@2323|unclassified Bacteria	2|Bacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
SYD2_k127_7075942_6	1340493.JNIF01000004_gene143	1.428e-71	250.0	COG1845@1|root,COG1845@2|Bacteria,3Y414@57723|Acidobacteria	57723|Acidobacteria	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SYD2_k127_7075942_0	234267.Acid_0498	5.319e-269	837.0	COG0843@1|root,COG0843@2|Bacteria,3Y2X6@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SYD2_k127_7075942_1	204669.Acid345_2996	4.059e-114	376.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GR@57723|Acidobacteria,2JHRF@204432|Acidobacteriia	204432|Acidobacteriia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
SYD2_k127_7075942_4	234267.Acid_0496	4.311e-93	314.0	COG1999@1|root,COG1999@2|Bacteria,3Y3XH@57723|Acidobacteria	57723|Acidobacteria	S	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SYD2_k127_7075942_15	1128421.JAGA01000003_gene2875	0.0008753	49.0	2EJZ3@1|root,33DPP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7075942_2	1267535.KB906767_gene1587	3.697e-112	376.0	COG4531@1|root,COG4531@2|Bacteria,3Y2X7@57723|Acidobacteria,2JIF8@204432|Acidobacteriia	204432|Acidobacteriia	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7075942_7	204669.Acid345_3000	1.435e-53	196.0	COG2010@1|root,COG2010@2|Bacteria,3Y2MN@57723|Acidobacteria,2JI6T@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SYD2_k127_7075942_10	1128421.JAGA01000003_gene2872	1.918e-22	98.0	COG2010@1|root,COG2010@2|Bacteria,2NPSE@2323|unclassified Bacteria	2|Bacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
SYD2_k127_7088357_1	292.DM42_3427	4.605e-06	53.0	2DR9C@1|root,33AS0@2|Bacteria,1NJ0U@1224|Proteobacteria,2VYD2@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7088357_0	525909.Afer_1020	4.544e-311	965.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4CNGZ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SYD2_k127_7097505_12	518766.Rmar_1244	6.109e-39	153.0	COG0248@1|root,COG0248@2|Bacteria,4NH03@976|Bacteroidetes,1FIST@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
SYD2_k127_7097505_17	1304874.JAFY01000002_gene1028	4.583e-17	93.0	COG5607@1|root,COG5607@2|Bacteria,3TBDS@508458|Synergistetes	508458|Synergistetes	FP	PFAM CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
SYD2_k127_7097505_20	1049564.TevJSym_az00020	4.456e-12	77.0	COG1285@1|root,COG1285@2|Bacteria,1PD3I@1224|Proteobacteria,1RQXT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
SYD2_k127_7097505_0	1303518.CCALI_00492	1.277e-198	643.0	COG0855@1|root,COG0855@2|Bacteria	2|Bacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SYD2_k127_7097505_3	330214.NIDE2540	1.785e-148	482.0	COG0044@1|root,COG0044@2|Bacteria,3J0D7@40117|Nitrospirae	40117|Nitrospirae	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SYD2_k127_7097505_4	338963.Pcar_1615	1.797e-123	404.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,43S21@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SYD2_k127_7097505_9	373903.Hore_09350	1.175e-67	236.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,3WAIW@53433|Halanaerobiales	186801|Clostridia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
SYD2_k127_7097505_7	926549.KI421517_gene1430	5.132e-99	335.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,47KYQ@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SYD2_k127_7097505_10	1232410.KI421428_gene1213	5.979e-66	233.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2WMJ5@28221|Deltaproteobacteria,43S93@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SYD2_k127_7097505_22	411154.GFO_3169	6.452e-05	55.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1HXT1@117743|Flavobacteriia	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SYD2_k127_7097505_21	880073.Calab_3374	4.885e-05	56.0	COG3170@1|root,COG3170@2|Bacteria,2NPQF@2323|unclassified Bacteria	2|Bacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SYD2_k127_7097505_15	1408473.JHXO01000006_gene1032	3.54e-33	131.0	2DNW1@1|root,32ZFG@2|Bacteria,4NUV5@976|Bacteroidetes,2G1AY@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7097505_18	1112212.JH584235_gene1567	4.392e-16	85.0	COG4319@1|root,COG4319@2|Bacteria,1PUQE@1224|Proteobacteria,2VD2U@28211|Alphaproteobacteria,2KAA8@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SYD2_k127_7097505_1	378806.STAUR_0571	6.313e-188	597.0	COG2304@1|root,COG2304@2|Bacteria,1R8EZ@1224|Proteobacteria,433AE@68525|delta/epsilon subdivisions,2WYFQ@28221|Deltaproteobacteria,2YY3M@29|Myxococcales	28221|Deltaproteobacteria	S	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
SYD2_k127_7097505_6	1128421.JAGA01000003_gene3195	5.812e-109	366.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
SYD2_k127_7097505_8	1267534.KB906755_gene4744	1.98e-86	297.0	COG0412@1|root,COG0412@2|Bacteria,3Y3UQ@57723|Acidobacteria,2JIIB@204432|Acidobacteriia	204432|Acidobacteriia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SYD2_k127_7097505_2	1340493.JNIF01000003_gene2599	4.673e-158	510.0	COG2204@1|root,COG2204@2|Bacteria,3Y2J1@57723|Acidobacteria	57723|Acidobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SYD2_k127_7097505_5	204669.Acid345_1393	3.545e-109	382.0	COG5000@1|root,COG5000@2|Bacteria,3Y32D@57723|Acidobacteria,2JIN2@204432|Acidobacteriia	204432|Acidobacteriia	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
SYD2_k127_7097505_14	1521187.JPIM01000003_gene2990	2.963e-33	140.0	COG1266@1|root,COG1266@2|Bacteria,2G76F@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SYD2_k127_7097505_16	1131269.AQVV01000028_gene31	1.391e-22	101.0	COG4911@1|root,COG4911@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SYD2_k127_7097505_23	317013.NY99_07960	0.0006071	51.0	COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria	1224|Proteobacteria	S	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SYD2_k127_7097505_11	404589.Anae109_0171	1.003e-44	181.0	COG1293@1|root,COG1293@2|Bacteria,1P028@1224|Proteobacteria,42MKF@68525|delta/epsilon subdivisions,2X6XB@28221|Deltaproteobacteria,2Z3DG@29|Myxococcales	28221|Deltaproteobacteria	K	Domain of unknown function (DUF814)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
SYD2_k127_7097505_13	1123371.ATXH01000003_gene1911	5.363e-35	153.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,2GIFB@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	KT	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,PAS
SYD2_k127_7119447_21	671143.DAMO_2942	1.614e-105	364.0	COG2812@1|root,COG2812@2|Bacteria,2NNK7@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SYD2_k127_7119447_22	1198114.AciX9_2754	7.873e-105	348.0	COG0583@1|root,COG0583@2|Bacteria,3Y31P@57723|Acidobacteria,2JIC0@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SYD2_k127_7119447_14	1121920.AUAU01000037_gene2735	4.708e-157	504.0	COG0119@1|root,COG0119@2|Bacteria,3Y2WT@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SYD2_k127_7119447_19	755731.Clo1100_0124	8.293e-115	381.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,36E5F@31979|Clostridiaceae	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SYD2_k127_7119447_3	292459.STH2116	9.23e-226	707.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SYD2_k127_7119447_27	1303518.CCALI_02738	2.021e-85	286.0	COG0066@1|root,COG0066@2|Bacteria	2|Bacteria	E	3-isopropylmalate dehydratase activity	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SYD2_k127_7119447_12	861299.J421_3663	3.735e-161	518.0	COG1228@1|root,COG1228@2|Bacteria,1ZSU7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SYD2_k127_7119447_51	177437.HRM2_33460	1.574e-31	137.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,42QGY@68525|delta/epsilon subdivisions,2WKHR@28221|Deltaproteobacteria,2MJDT@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SYD2_k127_7119447_5	469383.Cwoe_1088	1.483e-208	655.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SYD2_k127_7119447_0	1382356.JQMP01000003_gene1584	1.019e-319	1003.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,27XKK@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SYD2_k127_7119447_65	1266909.AUAG01000003_gene862	2.853e-11	69.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,1WXYW@135613|Chromatiales	135613|Chromatiales	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SYD2_k127_7119447_15	234267.Acid_1869	8.755e-139	449.0	COG0031@1|root,COG0031@2|Bacteria,3Y71B@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SYD2_k127_7119447_8	452637.Oter_0871	3.567e-187	605.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia,3K85F@414999|Opitutae	414999|Opitutae	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
SYD2_k127_7119447_64	404589.Anae109_4104	8.341e-12	68.0	COG1918@1|root,COG1918@2|Bacteria,1Q29B@1224|Proteobacteria,42VSV@68525|delta/epsilon subdivisions,2WS7A@28221|Deltaproteobacteria,2Z28N@29|Myxococcales	28221|Deltaproteobacteria	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
SYD2_k127_7119447_37	1244869.H261_10452	7.94e-68	243.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,2TSQB@28211|Alphaproteobacteria,2JU12@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SYD2_k127_7119447_38	667632.KB890165_gene2670	8.804e-63	226.0	COG1028@1|root,COG1028@2|Bacteria,1NTI2@1224|Proteobacteria,2VK21@28216|Betaproteobacteria,1K1T1@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	short-chain dehydrogenase	-	-	1.3.1.58	ko:K07535,ko:K10620	ko00362,ko00622,ko01120,ko01220,map00362,map00622,map01120,map01220	M00539,M00540	R05240,R05582	RC00057,RC00154	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
SYD2_k127_7119447_26	648757.Rvan_0037	9.546e-86	299.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2U2IH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
SYD2_k127_7119447_24	316057.RPD_1537	6.816e-88	305.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
SYD2_k127_7119447_47	1452718.JBOY01000055_gene1748	5.568e-39	149.0	2DNJV@1|root,32UJ6@2|Bacteria,1N4SS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7119447_29	398767.Glov_2399	1.282e-77	271.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,43V8M@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SYD2_k127_7119447_45	909663.KI867150_gene1130	2.456e-47	181.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42R04@68525|delta/epsilon subdivisions,2WMZ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM ATPase, BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SYD2_k127_7119447_71	351746.Pput_3634	0.0009967	46.0	COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria	1224|Proteobacteria	S	membrane	yqjD	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0043021,GO:0043024,GO:0044464,GO:0044877,GO:0060187,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF883
SYD2_k127_7119447_69	243233.MCA1292	1.142e-07	59.0	2DD9Q@1|root,2ZH70@2|Bacteria,1P8P5@1224|Proteobacteria,1SWFT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7119447_46	865937.Gilli_2897	7.883e-40	152.0	COG1764@1|root,COG1764@2|Bacteria,4PK2K@976|Bacteroidetes,1IGG0@117743|Flavobacteriia,2P7S9@244698|Gillisia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SYD2_k127_7119447_55	1479237.JMLY01000001_gene2639	8.397e-26	112.0	COG0517@1|root,COG0517@2|Bacteria,1QTVM@1224|Proteobacteria,1SFWU@1236|Gammaproteobacteria,46BCN@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SYD2_k127_7119447_56	1121382.JQKG01000012_gene154	6.484e-24	107.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SYD2_k127_7119447_63	644283.Micau_3690	1.328e-14	85.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4DD1H@85008|Micromonosporales	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SYD2_k127_7119447_1	526227.Mesil_3175	7.256e-304	954.0	COG0474@1|root,COG0474@2|Bacteria,1WICW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	pacL	-	3.6.3.6,3.6.3.8	ko:K01535,ko:K01537	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.2,3.A.3.3	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SYD2_k127_7119447_41	1051632.TPY_0302	7.083e-52	198.0	COG1252@1|root,COG1252@2|Bacteria,1UNP3@1239|Firmicutes,25H36@186801|Clostridia	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3,1.8.5.4	ko:K03885,ko:K17218	ko00190,ko00920,map00190,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SYD2_k127_7119447_7	1379698.RBG1_1C00001G0054	3.246e-195	614.0	COG2502@1|root,COG2502@2|Bacteria,2NNKP@2323|unclassified Bacteria	2|Bacteria	E	Aspartate-ammonia ligase	asnA	GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299	AsnA
SYD2_k127_7119447_44	1123037.AUDE01000032_gene2266	1.12e-47	175.0	COG1143@1|root,COG1143@2|Bacteria,4PKCQ@976|Bacteroidetes,1IJ7N@117743|Flavobacteriia	976|Bacteroidetes	C	ferredoxin	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
SYD2_k127_7119447_20	1519464.HY22_07315	1.892e-114	389.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	hsvB	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	ATP-grasp_4,Dala_Dala_lig_C
SYD2_k127_7119447_28	1122135.KB893135_gene868	4.045e-80	273.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2TT6M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SYD2_k127_7119447_39	1128421.JAGA01000001_gene2144	5.818e-60	218.0	COG3127@1|root,COG3127@2|Bacteria	2|Bacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SYD2_k127_7119447_49	1267535.KB906767_gene2392	3.195e-37	144.0	COG1846@1|root,COG1846@2|Bacteria,3Y861@57723|Acidobacteria	57723|Acidobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
SYD2_k127_7119447_17	867903.ThesuDRAFT_01903	1.463e-124	410.0	COG0644@1|root,COG0644@2|Bacteria,1TRTQ@1239|Firmicutes,24E1W@186801|Clostridia	186801|Clostridia	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl
SYD2_k127_7119447_33	1396418.BATQ01000007_gene1447	5.977e-73	263.0	2DR4U@1|root,33A62@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CreD
SYD2_k127_7119447_68	1547437.LL06_01570	7.044e-08	56.0	COG5368@1|root,COG5368@2|Bacteria,1NX2K@1224|Proteobacteria,2U1B2@28211|Alphaproteobacteria,43RF4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
SYD2_k127_7119447_66	639030.JHVA01000001_gene2268	4.532e-09	67.0	COG4994@1|root,COG4994@2|Bacteria,3Y8YB@57723|Acidobacteria,2JNQS@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SYD2_k127_7119447_67	1246445.ANAY01000012_gene75	8.278e-09	65.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4EIQ8@85012|Streptosporangiales	201174|Actinobacteria	S	YceI-like domain	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
SYD2_k127_7119447_61	391596.PBAL39_11627	2.107e-15	81.0	COG2259@1|root,COG2259@2|Bacteria,4NSHK@976|Bacteroidetes,1ITP8@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SYD2_k127_7119447_40	1185876.BN8_00648	6.403e-58	206.0	COG4244@1|root,COG4244@2|Bacteria,4NPHV@976|Bacteroidetes,47PWW@768503|Cytophagia	976|Bacteroidetes	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SYD2_k127_7119447_58	234267.Acid_7794	5.573e-20	94.0	2E5Q2@1|root,330EP@2|Bacteria,3Y5RC@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7119447_30	234267.Acid_7795	1.181e-75	261.0	COG1595@1|root,COG1595@2|Bacteria,3Y4KQ@57723|Acidobacteria	57723|Acidobacteria	K	region 4 type 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SYD2_k127_7119447_50	394221.Mmar10_0063	4.207e-33	133.0	COG3631@1|root,COG3631@2|Bacteria,1RD0K@1224|Proteobacteria,2UGFJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SYD2_k127_7119447_42	251221.35214645	1.198e-51	189.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
SYD2_k127_7119447_25	204669.Acid345_2272	6.668e-86	295.0	COG2010@1|root,COG2010@2|Bacteria,3Y5ZT@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SYD2_k127_7119447_57	1380347.JNII01000008_gene4314	1.098e-23	108.0	2C6EM@1|root,2ZFYQ@2|Bacteria,2GXX8@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
SYD2_k127_7119447_54	1089547.KB913013_gene1792	6.027e-27	116.0	2DR2Z@1|root,339YC@2|Bacteria,4P4XI@976|Bacteroidetes,47VKU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3828
SYD2_k127_7119447_6	525897.Dbac_1184	2.395e-206	657.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1MVRR@1224|Proteobacteria,42NSC@68525|delta/epsilon subdivisions,2WMAX@28221|Deltaproteobacteria,2MBD3@213115|Desulfovibrionales	28221|Deltaproteobacteria	CE	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
SYD2_k127_7119447_4	861299.J421_4036	6.064e-215	692.0	COG4774@1|root,COG4774@2|Bacteria,1ZTSY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	ko:K16090	-	-	-	-	ko00000,ko02000	1.B.14.1.11	-	-	Plug,TonB_dep_Rec
SYD2_k127_7119447_34	485918.Cpin_0998	3.66e-71	252.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,1IQI9@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SYD2_k127_7119447_59	1340493.JNIF01000003_gene4496	4.372e-18	99.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IP@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SYD2_k127_7119447_60	317936.Nos7107_3919	2.285e-16	89.0	COG1876@1|root,COG1876@2|Bacteria,1G4P0@1117|Cyanobacteria,1HIMP@1161|Nostocales	1117|Cyanobacteria	M	peptidase M15B and M15C DD-carboxypeptidase VanY	-	-	-	-	-	-	-	-	-	-	-	-	VanY
SYD2_k127_7119447_62	1123255.JHYS01000007_gene1705	1.134e-14	85.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,4A9SZ@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	mucD	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SYD2_k127_7119447_70	880073.Calab_2412	4.6e-05	54.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	HTH_3,NuiA,Pentapeptide,Pentapeptide_4
SYD2_k127_7119447_35	1340493.JNIF01000003_gene4178	3.684e-70	270.0	COG1629@1|root,COG3485@1|root,COG3485@2|Bacteria,COG4771@2|Bacteria,3Y3SU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SYD2_k127_7119447_48	1267535.KB906767_gene2804	1.123e-37	146.0	COG0789@1|root,COG0789@2|Bacteria,3Y4KX@57723|Acidobacteria,2JJA1@204432|Acidobacteriia	204432|Acidobacteriia	K	MerR HTH family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SYD2_k127_7119447_18	204669.Acid345_0979	8.402e-119	392.0	COG0484@1|root,COG0484@2|Bacteria,3Y2XW@57723|Acidobacteria,2JHWV@204432|Acidobacteriia	204432|Acidobacteriia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SYD2_k127_7119447_2	744872.Spica_2740	1.813e-260	817.0	COG0443@1|root,COG0443@2|Bacteria,2J5I0@203691|Spirochaetes	203691|Spirochaetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SYD2_k127_7119447_53	1158338.JNLJ01000005_gene1576	1.397e-28	122.0	COG0558@1|root,COG0558@2|Bacteria,2G47K@200783|Aquificae	200783|Aquificae	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SYD2_k127_7119447_43	1123399.AQVE01000001_gene529	2.575e-48	184.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
SYD2_k127_7119447_11	1283299.AUKG01000002_gene4159	3.233e-166	530.0	COG1830@1|root,COG1830@2|Bacteria,2I9V1@201174|Actinobacteria,4CRE8@84995|Rubrobacteria	84995|Rubrobacteria	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SYD2_k127_7119447_32	1379698.RBG1_1C00001G0128	9.253e-75	261.0	COG1606@1|root,COG1606@2|Bacteria,2NP5T@2323|unclassified Bacteria	2|Bacteria	L	tRNA processing	larE	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,Asn_synthase,NAD_synthase,QueC
SYD2_k127_7119447_31	398767.Glov_3164	4.054e-75	260.0	COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SYD2_k127_7119447_23	1173026.Glo7428_4077	2.52e-94	322.0	COG1641@1|root,COG1641@2|Bacteria,1G14X@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SYD2_k127_7119447_16	1267535.KB906767_gene4685	1.048e-134	452.0	COG1305@1|root,COG1305@2|Bacteria,3Y2TK@57723|Acidobacteria,2JHX7@204432|Acidobacteriia	204432|Acidobacteriia	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
SYD2_k127_7119447_13	1267535.KB906767_gene4685	2.843e-158	521.0	COG1305@1|root,COG1305@2|Bacteria,3Y2TK@57723|Acidobacteria,2JHX7@204432|Acidobacteriia	204432|Acidobacteriia	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
SYD2_k127_7119447_9	1267535.KB906767_gene4686	1.127e-174	569.0	COG1305@1|root,COG1305@2|Bacteria,3Y3A2@57723|Acidobacteria	57723|Acidobacteria	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
SYD2_k127_7119447_36	452637.Oter_3517	1.638e-69	252.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SYD2_k127_7119447_10	868595.Desca_1757	5.713e-173	565.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,260FM@186807|Peptococcaceae	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
SYD2_k127_7188207_8	1267533.KB906733_gene2890	0.0001006	53.0	29QWH@1|root,30BWY@2|Bacteria,3Y4SG@57723|Acidobacteria,2JJDK@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7188207_6	1229203.KI301992_gene1923	5.036e-06	56.0	COG3428@1|root,COG3428@2|Bacteria,2I7V5@201174|Actinobacteria,3UX0M@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SYD2_k127_7188207_2	765910.MARPU_08125	1.421e-38	154.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,1WXMB@135613|Chromatiales	135613|Chromatiales	M	Soluble lytic murein transglycosylase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
SYD2_k127_7188207_3	1500894.JQNN01000001_gene3284	4.049e-38	149.0	COG3861@1|root,COG3861@2|Bacteria,1MWBU@1224|Proteobacteria,2VR9U@28216|Betaproteobacteria,477EZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Cation transport regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7188207_0	697281.Mahau_1031	2.322e-88	301.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,42F72@68295|Thermoanaerobacterales	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SYD2_k127_7188207_7	420662.Mpe_A1221	6.919e-06	55.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,2WF1B@28216|Betaproteobacteria,1KPKM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CO	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7188207_4	518766.Rmar_1898	2.629e-26	123.0	COG0526@1|root,COG0526@2|Bacteria,4PIEG@976|Bacteroidetes,1FK6M@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SYD2_k127_7188207_1	156889.Mmc1_0245	4.117e-56	212.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SYD2_k127_7188207_5	1089550.ATTH01000001_gene698	1.439e-10	63.0	COG0665@1|root,COG0665@2|Bacteria,4PEB4@976|Bacteroidetes,1FIQR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
SYD2_k127_71886_9	278963.ATWD01000002_gene765	1.816e-15	85.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SYD2_k127_71886_2	1122176.KB903532_gene2606	3.349e-82	286.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SYD2_k127_71886_6	290397.Adeh_1232	7.64e-24	107.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2YVEN@29|Myxococcales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SYD2_k127_71886_4	204669.Acid345_4232	2.618e-67	245.0	COG0793@1|root,COG0793@2|Bacteria,3Y3A7@57723|Acidobacteria,2JHJK@204432|Acidobacteriia	204432|Acidobacteriia	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SYD2_k127_71886_1	269799.Gmet_3488	9.041e-118	390.0	2DBVK@1|root,2ZBBH@2|Bacteria,1PWZS@1224|Proteobacteria,432W2@68525|delta/epsilon subdivisions,2WXWI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SYD2_k127_71886_10	685035.ADAE01000011_gene1261	1.836e-06	59.0	COG3577@1|root,COG3577@2|Bacteria,1MYAD@1224|Proteobacteria,2U9RE@28211|Alphaproteobacteria,2K4GD@204457|Sphingomonadales	204457|Sphingomonadales	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
SYD2_k127_71886_8	671143.DAMO_0870	8.997e-16	90.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	ko:K03194	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	CHAP,SLT
SYD2_k127_71886_0	204669.Acid345_4697	7.9e-248	773.0	COG4799@1|root,COG4799@2|Bacteria,3Y3SM@57723|Acidobacteria,2JIBH@204432|Acidobacteriia	204432|Acidobacteriia	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SYD2_k127_71886_5	1121413.JMKT01000011_gene2225	9.49e-41	160.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,42N8F@68525|delta/epsilon subdivisions,2WK3B@28221|Deltaproteobacteria,2MA60@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SYD2_k127_71886_7	292459.STH1763	2.64e-19	94.0	COG3557@1|root,COG3557@2|Bacteria,1VC3B@1239|Firmicutes	1239|Firmicutes	J	Protein of unknown function (DUF402)	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
SYD2_k127_71886_3	562970.Btus_0343	7.088e-81	282.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HDH1@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	drrA	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
SYD2_k127_7202985_1	234267.Acid_5984	4.443e-68	240.0	COG0648@1|root,COG0648@2|Bacteria,3Y35C@57723|Acidobacteria	57723|Acidobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SYD2_k127_7202985_0	1267534.KB906754_gene3121	1.8e-282	893.0	COG0495@1|root,COG0495@2|Bacteria,3Y37K@57723|Acidobacteria,2JIGF@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
SYD2_k127_7202985_2	290397.Adeh_4096	3.04e-52	209.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,4340I@68525|delta/epsilon subdivisions,2X4FB@28221|Deltaproteobacteria,2Z047@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SYD2_k127_7218877_7	240015.ACP_1051	5.395e-91	312.0	COG3437@1|root,COG3437@2|Bacteria,3Y2TI@57723|Acidobacteria,2JHKC@204432|Acidobacteriia	204432|Acidobacteriia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
SYD2_k127_7218877_6	1128421.JAGA01000003_gene3695	5.805e-100	334.0	COG0338@1|root,COG0338@2|Bacteria	2|Bacteria	L	D12 class N6 adenine-specific DNA methyltransferase	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
SYD2_k127_7218877_0	194439.CT0923	2.863e-209	667.0	COG0531@1|root,COG0531@2|Bacteria,1FECX@1090|Chlorobi	1090|Chlorobi	E	C-terminus of AA_permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SYD2_k127_7218877_1	234267.Acid_1245	4.677e-191	610.0	COG0531@1|root,COG0531@2|Bacteria,3Y3QM@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SYD2_k127_7218877_8	329726.AM1_0713	3.881e-87	301.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SYD2_k127_7218877_12	215803.DB30_4642	6.435e-49	184.0	2D4UK@1|root,32THN@2|Bacteria,1PX7N@1224|Proteobacteria,434V7@68525|delta/epsilon subdivisions,2X91A@28221|Deltaproteobacteria,2Z1F4@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3142
SYD2_k127_7218877_4	1121920.AUAU01000012_gene2645	6.09e-104	345.0	COG0320@1|root,COG0320@2|Bacteria,3Y3D4@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SYD2_k127_7218877_9	1123508.JH636440_gene2559	1.543e-79	279.0	2EZN7@1|root,33ST8@2|Bacteria,2J2CB@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7218877_14	1123508.JH636440_gene2560	1.942e-35	140.0	2BYEG@1|root,349F2@2|Bacteria,2J42U@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7218877_5	997346.HMPREF9374_3051	9.569e-102	341.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli,27BPA@186824|Thermoactinomycetaceae	91061|Bacilli	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SYD2_k127_7218877_10	234267.Acid_0913	3.401e-56	204.0	COG0321@1|root,COG0321@2|Bacteria,3Y448@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,NUDIX
SYD2_k127_7218877_15	497964.CfE428DRAFT_0021	9.188e-28	115.0	COG3668@1|root,COG3668@2|Bacteria,46WMW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SYD2_k127_7218877_2	886293.Sinac_2843	4.379e-113	377.0	COG1680@1|root,COG2173@1|root,COG1680@2|Bacteria,COG2173@2|Bacteria,2IWSU@203682|Planctomycetes	203682|Planctomycetes	MV	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Peptidase_M15
SYD2_k127_7218877_11	862908.BMS_2150	8.772e-56	203.0	COG5113@1|root,COG3236@2|Bacteria,1NQ21@1224|Proteobacteria,4309B@68525|delta/epsilon subdivisions,2MT0Y@213481|Bdellovibrionales,2WV8M@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	hydrolase activity, hydrolyzing N-glycosyl compounds	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7218877_3	234267.Acid_1724	6.076e-107	361.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SYD2_k127_7218877_13	234267.Acid_4126	5.574e-36	139.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SYD2_k127_7243043_0	452637.Oter_4049	5.126e-176	567.0	COG0661@1|root,COG0661@2|Bacteria,46UJV@74201|Verrucomicrobia,3K7NS@414999|Opitutae	414999|Opitutae	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
SYD2_k127_7243043_1	1267535.KB906767_gene4789	4.634e-134	437.0	COG1064@1|root,COG1064@2|Bacteria,3Y34K@57723|Acidobacteria,2JIU5@204432|Acidobacteriia	204432|Acidobacteriia	S	Zinc-binding alcohol dehydrogenase family protein	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
SYD2_k127_7243043_4	197221.22296197	2.192e-37	148.0	COG0783@1|root,COG0783@2|Bacteria,1G4ZH@1117|Cyanobacteria	1117|Cyanobacteria	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
SYD2_k127_7243043_2	234267.Acid_0752	4.893e-41	161.0	COG0517@1|root,COG0517@2|Bacteria,3Y8IB@57723|Acidobacteria	57723|Acidobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SYD2_k127_7243043_7	1123392.AQWL01000001_gene1493	1.299e-07	62.0	2C51Y@1|root,33J3U@2|Bacteria,1P6QZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7243043_3	404589.Anae109_3080	7.415e-40	154.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WNF6@28221|Deltaproteobacteria,2Z15B@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SYD2_k127_7243043_6	1382306.JNIM01000001_gene1681	9.884e-18	83.0	28SF2@1|root,2ZERN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7243043_5	1379270.AUXF01000001_gene2673	6.268e-33	132.0	COG0520@1|root,COG0520@2|Bacteria,1ZSV8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SYD2_k127_728314_7	383372.Rcas_0549	3.551e-09	61.0	COG0648@1|root,COG0648@2|Bacteria,2G5XZ@200795|Chloroflexi,374VN@32061|Chloroflexia	32061|Chloroflexia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SYD2_k127_728314_3	1382359.JIAL01000001_gene2337	2.156e-99	339.0	COG2355@1|root,COG2355@2|Bacteria,3Y39A@57723|Acidobacteria,2JI1H@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SYD2_k127_728314_2	204669.Acid345_0712	3.014e-122	402.0	COG0115@1|root,COG0115@2|Bacteria,3Y32X@57723|Acidobacteria,2JI58@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SYD2_k127_728314_0	1304880.JAGB01000001_gene423	0.0	2651.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia	186801|Clostridia	G	Glycosyltransferase 36 associated	ndvB	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glyco_hydro_36,Glyco_transf_36,Glycoamylase
SYD2_k127_728314_5	573063.Metin_0198	4.381e-21	100.0	COG2314@1|root,COG3815@1|root,arCOG03293@2157|Archaea,arCOG03949@2157|Archaea,2XYU1@28890|Euryarchaeota,23RS2@183939|Methanococci	183939|Methanococci	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_728314_1	1267535.KB906767_gene3449	4.631e-126	412.0	COG1494@1|root,COG1494@2|Bacteria,3Y2XJ@57723|Acidobacteria,2JKWZ@204432|Acidobacteriia	204432|Acidobacteriia	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SYD2_k127_728314_6	1521187.JPIM01000034_gene3555	2.721e-09	69.0	COG0457@1|root,COG0457@2|Bacteria,2GAB4@200795|Chloroflexi,374UY@32061|Chloroflexia	32061|Chloroflexia	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2
SYD2_k127_728314_4	1430331.EP10_08725	4.971e-25	105.0	COG1960@1|root,COG1960@2|Bacteria,1TPVK@1239|Firmicutes,4HA7B@91061|Bacilli,1WERN@129337|Geobacillus	91061|Bacilli	C	Acyl-CoA dehydrogenase, N-terminal domain	B4168_2380	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SYD2_k127_7298189_4	1172186.KB911464_gene4917	5.024e-87	297.0	COG3186@1|root,COG3186@2|Bacteria,2GKCB@201174|Actinobacteria,2376D@1762|Mycobacteriaceae	201174|Actinobacteria	E	Biopterin-dependent aromatic amino acid hydroxylase	phhA	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
SYD2_k127_7298189_2	518766.Rmar_1677	2.062e-124	408.0	COG0031@1|root,COG0031@2|Bacteria,4NF7E@976|Bacteroidetes,1FIN7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	cysM	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SYD2_k127_7298189_3	357808.RoseRS_4472	1.477e-109	368.0	COG0626@1|root,COG0626@2|Bacteria,2G684@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SYD2_k127_7298189_5	44251.PDUR_03265	1.096e-46	173.0	COG1310@1|root,COG1310@2|Bacteria,1VKT4@1239|Firmicutes	1239|Firmicutes	S	JAB/MPN domain	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
SYD2_k127_7298189_1	1268072.PSAB_02820	5.018e-200	633.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,271Z6@186822|Paenibacillaceae	91061|Bacilli	H	ThiS family	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
SYD2_k127_7298189_7	671143.DAMO_0863	7.078e-15	77.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
SYD2_k127_7298189_0	324602.Caur_2963	0.0	1173.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi,376J5@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SYD2_k127_7298189_6	1128421.JAGA01000001_gene2128	7.21e-26	108.0	2BWQN@1|root,347D7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7299552_1	204669.Acid345_3936	2.314e-165	528.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SYD2_k127_7299552_4	1122927.KB895414_gene5126	4.926e-100	335.0	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,26QXS@186822|Paenibacillaceae	91061|Bacilli	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SYD2_k127_7299552_0	886293.Sinac_5685	2.265e-223	709.0	COG0308@1|root,COG0308@2|Bacteria,2J268@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Leukotriene A4 hydrolase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
SYD2_k127_7299552_7	536019.Mesop_2925	5.292e-48	179.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9
SYD2_k127_7299552_6	234267.Acid_6639	1.367e-53	200.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SYD2_k127_7299552_5	1267534.KB906755_gene4690	1.336e-59	216.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3	ko:K07315,ko:K16928	-	M00582	-	-	ko00000,ko00002,ko01000,ko02000,ko03021	3.A.1.33	-	-	HAMP,HATPase_c_2,SpoIIE,dCache_1
SYD2_k127_7299552_3	1267534.KB906755_gene4691	8.105e-106	349.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SYD2_k127_7299552_2	1267533.KB906733_gene2989	1.159e-158	518.0	COG0642@1|root,COG2205@2|Bacteria,3Y2M7@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SYD2_k127_7299552_8	861299.J421_2314	7.73e-41	156.0	COG0477@1|root,COG2814@2|Bacteria,1ZT84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SYD2_k127_7308758_0	1487953.JMKF01000015_gene6227	8.624e-63	220.0	COG1670@1|root,COG1670@2|Bacteria,1G6XM@1117|Cyanobacteria,1HCHH@1150|Oscillatoriales	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SYD2_k127_7308758_2	234267.Acid_4774	4.19e-23	104.0	2E32R@1|root,32Y2Y@2|Bacteria,3Y5RV@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7308758_3	405948.SACE_0308	5.159e-18	84.0	2E3SC@1|root,32YPX@2|Bacteria,2HPCF@201174|Actinobacteria,4E4BJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
SYD2_k127_7308758_6	402626.Rpic_2855	5.248e-09	63.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,1K8SG@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Cytochrome c-type biogenesis protein	cycH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2
SYD2_k127_7308758_1	1165096.ARWF01000001_gene1610	1.35e-37	149.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2VU7C@28216|Betaproteobacteria	28216|Betaproteobacteria	P	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
SYD2_k127_7308758_4	1266925.JHVX01000001_gene2487	8.761e-17	80.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,372UU@32003|Nitrosomonadales	28216|Betaproteobacteria	CO	oxidoreductase DsbE	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
SYD2_k127_7309403_1	671143.DAMO_0706	5.629e-87	295.0	COG0403@1|root,COG0403@2|Bacteria,2NNP1@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204	1.4.4.2	ko:K00281,ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SYD2_k127_7309403_0	204669.Acid345_2458	4.452e-192	612.0	COG1003@1|root,COG1003@2|Bacteria,3Y2UZ@57723|Acidobacteria,2JIAN@204432|Acidobacteriia	204432|Acidobacteriia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SYD2_k127_7309403_2	439235.Dalk_2729	9.152e-48	178.0	COG3809@1|root,COG3809@2|Bacteria,1PZB0@1224|Proteobacteria,433GD@68525|delta/epsilon subdivisions,2WXX5@28221|Deltaproteobacteria,2MP8T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
SYD2_k127_7309403_3	1121920.AUAU01000022_gene2473	8.366e-26	111.0	COG3411@1|root,COG3411@2|Bacteria,3Y54Q@57723|Acidobacteria	57723|Acidobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7310416_20	1499967.BAYZ01000027_gene1815	3.781e-22	98.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SYD2_k127_7310416_7	1521187.JPIM01000061_gene990	5.59e-196	623.0	COG1960@1|root,COG1960@2|Bacteria,2G7V8@200795|Chloroflexi,375QJ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SYD2_k127_7310416_19	591001.Acfer_0224	4.175e-25	116.0	COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,4H1Z7@909932|Negativicutes	909932|Negativicutes	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SYD2_k127_7310416_17	645991.Sgly_1590	1.027e-52	192.0	COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,24IH4@186801|Clostridia,26236@186807|Peptococcaceae	186801|Clostridia	S	PFAM LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SYD2_k127_7310416_18	234267.Acid_0972	7.747e-32	135.0	COG1708@1|root,COG1708@2|Bacteria,3Y7NX@57723|Acidobacteria	57723|Acidobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7310416_4	1463885.KL578366_gene2793	2.373e-239	754.0	COG2373@1|root,COG2373@2|Bacteria,2H4M3@201174|Actinobacteria	201174|Actinobacteria	I	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Catalase
SYD2_k127_7310416_13	1254432.SCE1572_24150	6.758e-95	317.0	2DSHD@1|root,33G4R@2|Bacteria	2|Bacteria	-	-	-	-	1.13.11.33	ko:K19246	ko00590,ko01100,map00590,map01100	-	R01593	RC00561	ko00000,ko00001,ko01000	-	-	-	Lipoxygenase
SYD2_k127_7310416_10	1123023.JIAI01000004_gene8048	2.472e-108	355.0	2DSHD@1|root,33G4R@2|Bacteria	2|Bacteria	-	-	-	-	1.13.11.33	ko:K19246	ko00590,ko01100,map00590,map01100	-	R01593	RC00561	ko00000,ko00001,ko01000	-	-	-	Lipoxygenase
SYD2_k127_7310416_11	1192034.CAP_5172	3.603e-106	361.0	COG2114@1|root,COG2114@2|Bacteria,1MY09@1224|Proteobacteria	1224|Proteobacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE3,Guanylate_cyc
SYD2_k127_7310416_1	1278073.MYSTI_03564	0.0	1347.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WJ2A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SYD2_k127_7310416_15	1278073.MYSTI_03565	6.356e-74	265.0	COG0845@1|root,COG0845@2|Bacteria,1R866@1224|Proteobacteria,43AD7@68525|delta/epsilon subdivisions,2X5T4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K18302	-	M00642	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2,8.A.1	-	-	HlyD_D23
SYD2_k127_7310416_14	1267533.KB906735_gene4603	2.906e-81	291.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SYD2_k127_7310416_22	1267533.KB906737_gene1859	2.045e-09	67.0	2C6A3@1|root,34625@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7310416_21	1278073.MYSTI_02783	3.483e-12	73.0	2C852@1|root,32YB2@2|Bacteria,1N9HY@1224|Proteobacteria,42WCG@68525|delta/epsilon subdivisions,2WS1H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
SYD2_k127_7310416_9	32057.KB217478_gene1281	1.634e-161	524.0	COG0654@1|root,COG0654@2|Bacteria,1G5VZ@1117|Cyanobacteria,1HS4Z@1161|Nostocales	1117|Cyanobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SYD2_k127_7310416_5	330214.NIDE3498	1.912e-224	724.0	COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	fhlA	GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141	-	ko:K02584,ko:K12146,ko:K12266,ko:K15836,ko:K21009	ko02020,ko02025,ko05132,map02020,map02025,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,GAF_3,HTH_8,Sigma54_activat
SYD2_k127_7310416_23	383372.Rcas_3002	2.375e-06	54.0	COG0745@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9,Response_reg
SYD2_k127_7310416_12	251229.Chro_2996	1.698e-100	332.0	COG1741@1|root,COG1741@2|Bacteria,1G0UH@1117|Cyanobacteria,3VJ25@52604|Pleurocapsales	1117|Cyanobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
SYD2_k127_7310416_24	403833.Pmob_0376	5.405e-06	57.0	COG1763@1|root,COG1763@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	-	ko:K03753,ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	-
SYD2_k127_7310416_16	1519464.HY22_04250	6.967e-54	193.0	COG1956@1|root,COG1956@2|Bacteria,1FF9S@1090|Chlorobi	1090|Chlorobi	T	GAF domain	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
SYD2_k127_7310416_2	215803.DB30_8023	0.0	1060.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2X7DH@28221|Deltaproteobacteria,2YUKN@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
SYD2_k127_7310416_0	234267.Acid_3931	0.0	1424.0	COG2866@1|root,COG2866@2|Bacteria,3Y3X8@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SYD2_k127_7310416_3	1237149.C900_02054	7.204e-299	940.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,47YDB@768503|Cytophagia	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
SYD2_k127_7310416_8	861299.J421_1410	4.554e-191	605.0	COG0624@1|root,COG0624@2|Bacteria,1ZSYH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SYD2_k127_7310416_6	530564.Psta_3388	7.968e-198	679.0	COG0457@1|root,COG0457@2|Bacteria,2IZTX@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7330183_3	765912.Thimo_3580	2.004e-06	59.0	COG1493@1|root,COG1493@2|Bacteria,1RE0J@1224|Proteobacteria,1SBIT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7330183_1	1324957.K933_00537	3.814e-40	170.0	COG0034@1|root,COG0367@1|root,arCOG00071@2157|Archaea,arCOG00093@2157|Archaea,2XV5E@28890|Euryarchaeota,23WDA@183963|Halobacteria	183963|Halobacteria	E	COG0367 Asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SYD2_k127_7330183_4	111780.Sta7437_1000	4.449e-06	53.0	2EADQ@1|root,334HC@2|Bacteria,1G9ZF@1117|Cyanobacteria	1117|Cyanobacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SYD2_k127_7330183_2	215803.DB30_2132	1.942e-33	147.0	2BQ9J@1|root,32J4D@2|Bacteria,1PCIN@1224|Proteobacteria,438GB@68525|delta/epsilon subdivisions,2XA2E@28221|Deltaproteobacteria,2YWWE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7330183_0	395961.Cyan7425_1024	5.944e-100	339.0	COG4076@1|root,COG4076@2|Bacteria,1G4RK@1117|Cyanobacteria	1117|Cyanobacteria	J	PRMT5 arginine-N-methyltransferase	-	-	2.1.1.319	ko:K11434	ko04068,ko04922,map04068,map04922	-	R11216,R11217,R11219	RC00003,RC02120,RC03388,RC03390	ko00000,ko00001,ko01000,ko03036	-	-	-	PRMT5_C,PrmA
SYD2_k127_7333790_11	204669.Acid345_0705	3.598e-18	89.0	COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria,2JI8N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SYD2_k127_7333790_10	1214101.BN159_8358	4.487e-25	118.0	COG1874@1|root,COG2931@1|root,COG4409@1|root,COG1874@2|Bacteria,COG2931@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	BNR,BNR_2
SYD2_k127_7333790_1	1382306.JNIM01000001_gene3774	2.116e-115	383.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SYD2_k127_7333790_2	234267.Acid_2800	1.411e-90	308.0	COG0010@1|root,COG0010@2|Bacteria,3Y46E@57723|Acidobacteria	57723|Acidobacteria	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SYD2_k127_7333790_12	445973.CLOBAR_02288	1.033e-16	90.0	COG2304@1|root,COG2304@2|Bacteria,1VIXG@1239|Firmicutes,24S4H@186801|Clostridia	186801|Clostridia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
SYD2_k127_7333790_9	945713.IALB_2664	3.852e-34	139.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SYD2_k127_7333790_6	348780.NP_0956A	1.077e-44	172.0	arCOG01781@1|root,arCOG01781@2157|Archaea,2XSY0@28890|Euryarchaeota,23RWZ@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	scm	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SYD2_k127_7333790_0	1267535.KB906767_gene5021	3.367e-188	598.0	COG0017@1|root,COG0017@2|Bacteria,3Y350@57723|Acidobacteria,2JI7K@204432|Acidobacteriia	204432|Acidobacteriia	J	class II (D K	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SYD2_k127_7333790_7	706587.Desti_1483	1.106e-38	158.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,42TUJ@68525|delta/epsilon subdivisions,2WQ4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	phosphotransferase related to Ser Thr protein kinases	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
SYD2_k127_7333790_5	391625.PPSIR1_31393	4.382e-48	184.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WKAF@28221|Deltaproteobacteria,2Z2Y6@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3178	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SYD2_k127_7333790_4	478741.JAFS01000002_gene862	1.002e-64	235.0	COG1472@1|root,COG1472@2|Bacteria,46S5G@74201|Verrucomicrobia,37G7H@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SYD2_k127_7333790_3	1267533.KB906738_gene2105	8.236e-84	298.0	COG0747@1|root,COG0747@2|Bacteria,3Y44K@57723|Acidobacteria,2JHM9@204432|Acidobacteriia	204432|Acidobacteriia	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SYD2_k127_7333790_8	1131269.AQVV01000001_gene1325	3.176e-38	149.0	COG0009@1|root,COG0009@2|Bacteria	2|Bacteria	J	L-threonylcarbamoyladenylate synthase	prmC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
SYD2_k127_7352751_9	234267.Acid_3935	8.726e-38	144.0	COG1181@1|root,COG1181@2|Bacteria,3Y9AM@57723|Acidobacteria	57723|Acidobacteria	M	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
SYD2_k127_7352751_15	1449346.JQMO01000003_gene5207	3.833e-09	69.0	COG5305@1|root,COG5305@2|Bacteria,2GN7C@201174|Actinobacteria,2M1HB@2063|Kitasatospora	201174|Actinobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
SYD2_k127_7352751_8	926561.KB900617_gene2105	3.896e-45	177.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia,3WC93@53433|Halanaerobiales	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SYD2_k127_7352751_0	234267.Acid_3898	1.033e-198	642.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	2|Bacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,VWA,VWA_2
SYD2_k127_7352751_2	682795.AciX8_1432	6.393e-117	389.0	COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria,2JKK7@204432|Acidobacteriia	204432|Acidobacteriia	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SYD2_k127_7352751_3	1356852.N008_05325	5.542e-114	405.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NK8Q@976|Bacteroidetes,47KVN@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
SYD2_k127_7352751_6	945713.IALB_2758	2.8e-55	201.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SYD2_k127_7352751_11	765420.OSCT_0768	1.145e-20	106.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
SYD2_k127_7352751_13	1123248.KB893348_gene222	9.331e-11	74.0	COG3210@1|root,COG3210@2|Bacteria,4PPRF@976|Bacteroidetes,1IZDI@117747|Sphingobacteriia	976|Bacteroidetes	U	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
SYD2_k127_7352751_10	324602.Caur_0299	5.371e-22	111.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
SYD2_k127_7352751_14	1270193.JARP01000002_gene633	1.306e-10	74.0	COG0018@1|root,COG5164@1|root,COG5295@1|root,COG0018@2|Bacteria,COG5164@2|Bacteria,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes,1IKUQ@117743|Flavobacteriia,2NXWT@237|Flavobacterium	976|Bacteroidetes	UW	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Peptidase_S74
SYD2_k127_7352751_7	323848.Nmul_A0701	1.824e-51	188.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2VQ83@28216|Betaproteobacteria,371PF@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Scaffold protein Nfu/NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
SYD2_k127_7352751_5	1191523.MROS_1703	1.389e-56	205.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SYD2_k127_7352751_12	861299.J421_0340	8.787e-14	83.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097,PA14
SYD2_k127_7352751_17	1384056.N787_04785	1.059e-05	56.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,1X62K@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SYD2_k127_7352751_16	1047013.AQSP01000139_gene2326	4.235e-07	60.0	COG5660@1|root,COG5660@2|Bacteria	2|Bacteria	S	Putative zinc-finger	sigC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	zf-HC2
SYD2_k127_7352751_4	926566.Terro_3241	5.257e-61	218.0	COG1595@1|root,COG1595@2|Bacteria,3Y3HD@57723|Acidobacteria,2JHY0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SYD2_k127_7352751_1	518766.Rmar_1523	1.545e-136	444.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1FITT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SYD2_k127_7370581_9	1267533.KB906733_gene3398	4.532e-13	74.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SYD2_k127_7370581_0	394221.Mmar10_2289	3.713e-166	540.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,43WFY@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SYD2_k127_7370581_4	215803.DB30_5004	2.133e-43	167.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42S9C@68525|delta/epsilon subdivisions,2WM4G@28221|Deltaproteobacteria,2YXFQ@29|Myxococcales	28221|Deltaproteobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SYD2_k127_7370581_5	234267.Acid_0694	1.005e-39	155.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	-	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
SYD2_k127_7370581_1	661478.OP10G_2288	8.61e-150	494.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,PA,Peptidase_M28
SYD2_k127_7370581_8	247490.KSU1_C0079	8.39e-21	93.0	2E90H@1|root,31X4M@2|Bacteria,2J4J2@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7370581_7	765912.Thimo_1662	6.645e-29	117.0	2C1SS@1|root,32YN6@2|Bacteria,1NNFV@1224|Proteobacteria,1SS40@1236|Gammaproteobacteria,1X173@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7370581_2	1382359.JIAL01000001_gene96	1.54e-135	445.0	COG1282@1|root,COG1282@2|Bacteria,3Y42H@57723|Acidobacteria,2JM1F@204432|Acidobacteriia	204432|Acidobacteriia	C	NAD(P) transhydrogenase beta subunit	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SYD2_k127_7370581_6	671143.DAMO_0094	1.411e-30	124.0	COG3288@1|root,COG3288@2|Bacteria,2NRJW@2323|unclassified Bacteria	2|Bacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntA-2	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SYD2_k127_7370581_3	1173026.Glo7428_3011	9.793e-57	203.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria	1117|Cyanobacteria	C	NAD(P) transhydrogenase, alpha subunit	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SYD2_k127_7427608_2	204669.Acid345_3751	5.596e-11	66.0	COG3547@1|root,COG3547@2|Bacteria,3Y5SI@57723|Acidobacteria,2JNJP@204432|Acidobacteriia	57723|Acidobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SYD2_k127_7427608_0	1157708.KB907458_gene1736	1.849e-137	450.0	COG0412@1|root,COG0412@2|Bacteria,1MW88@1224|Proteobacteria,2VMBW@28216|Betaproteobacteria,4AE3K@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH,SnoaL_2
SYD2_k127_7427608_1	264732.Moth_0156	5.964e-59	213.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,25E7A@186801|Clostridia	186801|Clostridia	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,Usp
SYD2_k127_7429266_8	1303518.CCALI_01715	1.408e-61	215.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
SYD2_k127_7429266_1	643473.KB235930_gene4348	5.63e-143	467.0	COG2124@1|root,COG2124@2|Bacteria,1G3SX@1117|Cyanobacteria,1HMP2@1161|Nostocales	1117|Cyanobacteria	Q	PFAM cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SYD2_k127_7429266_7	631362.Thi970DRAFT_04732	3.831e-62	224.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1WWC4@135613|Chromatiales	135613|Chromatiales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SYD2_k127_7429266_3	1089553.Tph_c14050	7.082e-98	332.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SYD2_k127_7429266_11	240015.ACP_3266	8.845e-14	77.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_19,HTH_3,HTH_31,TPR_12,TPR_8
SYD2_k127_7429266_4	1267534.KB906754_gene2801	5.511e-97	339.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria,2JHNE@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SYD2_k127_7429266_2	886293.Sinac_0554	2.933e-108	367.0	COG0515@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1716@2|Bacteria,2J2EJ@203682|Planctomycetes	203682|Planctomycetes	KLT	Forkhead associated domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
SYD2_k127_7429266_9	502025.Hoch_1527	5.538e-53	207.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,PEGA,Pkinase,TPR_12
SYD2_k127_7429266_6	1237149.C900_00072	2.51e-81	282.0	COG1273@1|root,COG1273@2|Bacteria,4NHHQ@976|Bacteroidetes,47PE5@768503|Cytophagia	976|Bacteroidetes	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SYD2_k127_7429266_10	102129.Lepto7375DRAFT_4225	5.233e-21	98.0	COG1943@1|root,COG1943@2|Bacteria,1G6SS@1117|Cyanobacteria,1HBRS@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SYD2_k127_7429266_0	448385.sce8781	1.183e-193	620.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria,2YXCT@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase beta thumb	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SYD2_k127_7429266_5	1163408.UU9_07109	4.682e-96	327.0	COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria	1224|Proteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SYD2_k127_7429833_14	483219.LILAB_04485	8.163e-09	66.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
SYD2_k127_7429833_15	204669.Acid345_3273	5.46e-08	63.0	2EK74@1|root,33DXH@2|Bacteria,3Y5VZ@57723|Acidobacteria,2JK2Y@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7429833_4	1033734.CAET01000048_gene1646	8.401e-82	287.0	COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,1ZBRB@1386|Bacillus	91061|Bacilli	S	COG1078 HD superfamily phosphohydrolases	ywfO	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
SYD2_k127_7429833_1	1340493.JNIF01000004_gene526	1.131e-201	664.0	COG1629@1|root,COG4771@2|Bacteria,3Y33S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SYD2_k127_7429833_18	203124.Tery_1499	0.0002333	53.0	COG0457@1|root,COG5010@1|root,COG0457@2|Bacteria,COG5010@2|Bacteria,1G36K@1117|Cyanobacteria,1H9PH@1150|Oscillatoriales	1117|Cyanobacteria	O	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SYD2_k127_7429833_2	1121920.AUAU01000012_gene2631	2.757e-117	416.0	COG1629@1|root,COG4771@2|Bacteria,3Y3ZU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SYD2_k127_7429833_11	204669.Acid345_3941	2.289e-14	85.0	COG0457@1|root,COG0457@2|Bacteria,3Y7UM@57723|Acidobacteria,2JNRM@204432|Acidobacteriia	204432|Acidobacteriia	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7429833_13	1183438.GKIL_2841	9.432e-10	70.0	COG0457@1|root,COG0457@2|Bacteria	1183438.GKIL_2841|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7429833_9	1340493.JNIF01000004_gene509	2.04e-42	176.0	2DBAV@1|root,2Z84I@2|Bacteria,3Y9AH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7429833_7	1089548.KI783301_gene2821	5.264e-70	243.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,3WFAX@539002|Bacillales incertae sedis	91061|Bacilli	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08945	DHBP_synthase,GTP_cyclohydro2
SYD2_k127_7429833_8	1121013.P873_00825	7.723e-50	190.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1SP18@1236|Gammaproteobacteria,1X5DE@135614|Xanthomonadales	135614|Xanthomonadales	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF
SYD2_k127_7429833_3	269799.Gmet_3244	1.633e-88	307.0	COG3875@1|root,COG3875@2|Bacteria,1RFFK@1224|Proteobacteria,43B2T@68525|delta/epsilon subdivisions,2X6GN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	larA	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SYD2_k127_7429833_5	1489678.RDMS_12985	1.786e-75	264.0	COG1230@1|root,COG1230@2|Bacteria	2|Bacteria	P	cation diffusion facilitator family transporter	zitB	GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	iNRG857_1313.NRG857_03325,iPC815.YPO1129	Cation_efflux,ZT_dimer
SYD2_k127_7429833_0	1382359.JIAL01000001_gene2689	7.329e-210	672.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3NT@57723|Acidobacteria,2JIBK@204432|Acidobacteriia	204432|Acidobacteriia	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
SYD2_k127_7429833_10	1122947.FR7_1594	2.665e-32	139.0	COG0859@1|root,COG0859@2|Bacteria,1TRN2@1239|Firmicutes,4H25K@909932|Negativicutes	909932|Negativicutes	M	lipopolysaccharide heptosyltransferase	rfaF	-	-	ko:K02841,ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SYD2_k127_7429833_6	518766.Rmar_1876	4e-70	257.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1FIVK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SYD2_k127_7429833_17	330214.NIDE1600	0.0001846	53.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Big_3,PT-HINT,RHS_repeat
SYD2_k127_7429833_16	742743.HMPREF9453_00655	0.0001055	54.0	COG0810@1|root,COG0810@2|Bacteria,1VDCH@1239|Firmicutes,4H54A@909932|Negativicutes	909932|Negativicutes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SYD2_k127_7429833_12	880073.Calab_3013	9.815e-12	76.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,GGDEF,Response_reg
SYD2_k127_7436951_13	570967.JMLV01000002_gene1609	2.568e-08	61.0	COG3011@1|root,COG3011@2|Bacteria,1Q3II@1224|Proteobacteria,2UFWG@28211|Alphaproteobacteria,2JTZY@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
SYD2_k127_7436951_3	1123261.AXDW01000004_gene2796	1.629e-103	353.0	COG1228@1|root,COG1228@2|Bacteria,1R40Z@1224|Proteobacteria,1S3FZ@1236|Gammaproteobacteria,1X54C@135614|Xanthomonadales	135614|Xanthomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SYD2_k127_7436951_0	234267.Acid_7675	2.233e-226	721.0	COG0480@1|root,COG0480@2|Bacteria,3Y2RR@57723|Acidobacteria	57723|Acidobacteria	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SYD2_k127_7436951_14	1332071.L581_0863	9.294e-07	58.0	COG3678@1|root,COG3678@2|Bacteria,1RBDH@1224|Proteobacteria,1S2DT@1236|Gammaproteobacteria,403C3@613|Serratia	1236|Gammaproteobacteria	NPTU	LTXXQ motif protein family	spy	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0010033,GO:0014070,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051082,GO:0061077,GO:1990507	-	ko:K06006	-	-	-	-	ko00000,ko03110	-	-	-	LTXXQ
SYD2_k127_7436951_15	118797.XP_007447836.1	0.0001666	56.0	28KVH@1|root,2QTBY@2759|Eukaryota,39SN3@33154|Opisthokonta,3BDC9@33208|Metazoa,3CYDR@33213|Bilateria,48A6G@7711|Chordata,490QE@7742|Vertebrata,3JD04@40674|Mammalia,4J1RR@91561|Cetartiodactyla	33208|Metazoa	S	Centrosomal protein	CEP250	GO:0000086,GO:0000226,GO:0000278,GO:0000922,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005813,GO:0005814,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007098,GO:0007346,GO:0008022,GO:0008104,GO:0008150,GO:0009987,GO:0010389,GO:0010457,GO:0010564,GO:0015630,GO:0016043,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0022402,GO:0022406,GO:0022607,GO:0030030,GO:0030031,GO:0030997,GO:0031023,GO:0031616,GO:0032879,GO:0032880,GO:0032886,GO:0032991,GO:0033036,GO:0033043,GO:0033365,GO:0034613,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044464,GO:0044770,GO:0044772,GO:0044782,GO:0044839,GO:0046605,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0051179,GO:0051493,GO:0051640,GO:0051641,GO:0051726,GO:0060271,GO:0060341,GO:0065007,GO:0070507,GO:0070727,GO:0070925,GO:0071840,GO:0097711,GO:0120031,GO:0120036,GO:0140056,GO:1901987,GO:1901990,GO:1902749,GO:1903047,GO:1903827,GO:1903829,GO:1904779,GO:1904781,GO:1905515	-	ko:K16464	-	-	-	-	ko00000,ko03036	-	-	-	Rootletin
SYD2_k127_7436951_1	1121904.ARBP01000038_gene2566	6.8e-212	675.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,47JTA@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9
SYD2_k127_7436951_2	1122604.JONR01000033_gene4	2.453e-113	370.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,1RQNI@1236|Gammaproteobacteria,1X51V@135614|Xanthomonadales	135614|Xanthomonadales	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SYD2_k127_7436951_7	1123508.JH636449_gene7286	2.008e-23	107.0	COG3386@1|root,COG3386@2|Bacteria,2J0PJ@203682|Planctomycetes	203682|Planctomycetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7436951_4	290397.Adeh_0529	2.09e-60	213.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,42SN0@68525|delta/epsilon subdivisions,2WPY6@28221|Deltaproteobacteria,2Z0UJ@29|Myxococcales	28221|Deltaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
SYD2_k127_7436951_8	1445613.JALM01000005_gene1186	6.086e-21	107.0	COG0346@1|root,COG0346@2|Bacteria,2H5Y5@201174|Actinobacteria,4EBMJ@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SYD2_k127_7436951_10	234267.Acid_4609	1.908e-19	102.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SYD2_k127_7436951_9	1403819.BATR01000124_gene4382	8.076e-20	103.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SYD2_k127_7436951_6	204669.Acid345_3132	9.008e-40	154.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SYD2_k127_7436951_12	1279009.ADICEAN_02616	1.477e-13	76.0	COG4334@1|root,COG4334@2|Bacteria,4NSAC@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
SYD2_k127_7436951_5	404589.Anae109_0216	4.894e-57	201.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,42TZA@68525|delta/epsilon subdivisions,2WRHK@28221|Deltaproteobacteria,2Z03M@29|Myxococcales	28221|Deltaproteobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SYD2_k127_7489534_1	861299.J421_3346	1.739e-213	672.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SYD2_k127_7489534_2	861299.J421_3345	6.477e-209	658.0	COG3185@1|root,COG3185@2|Bacteria,1ZT5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
SYD2_k127_7489534_6	880073.Calab_1746	3.716e-44	163.0	2CIU6@1|root,32S8H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7489534_5	880071.Fleli_3451	8.773e-56	204.0	COG1024@1|root,COG1024@2|Bacteria,4NI32@976|Bacteroidetes,47MCZ@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SYD2_k127_7489534_4	926550.CLDAP_14980	2.469e-56	199.0	COG2185@1|root,COG2185@2|Bacteria,2G6S9@200795|Chloroflexi	200795|Chloroflexi	I	PFAM cobalamin B12-binding domain protein	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SYD2_k127_7489534_0	204669.Acid345_1454	1.004e-223	706.0	COG1884@1|root,COG1884@2|Bacteria,3Y2PQ@57723|Acidobacteria,2JHJN@204432|Acidobacteriia	204432|Acidobacteriia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SYD2_k127_7489534_7	696369.KI912183_gene2337	1.744e-05	53.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	divIC	-	-	ko:K05589,ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
SYD2_k127_7489534_3	1382359.JIAL01000001_gene12	9.148e-205	642.0	COG1964@1|root,COG1964@2|Bacteria,3Y2WC@57723|Acidobacteria,2JHTH@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
SYD2_k127_7499538_1	640081.Dsui_0794	3.374e-06	59.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2VH5R@28216|Betaproteobacteria,2KUU7@206389|Rhodocyclales	206389|Rhodocyclales	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
SYD2_k127_7499538_0	1267535.KB906767_gene5516	2.163e-06	59.0	COG3103@1|root,COG3103@2|Bacteria,3Y3S0@57723|Acidobacteria,2JIYP@204432|Acidobacteriia	204432|Acidobacteriia	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_8
SYD2_k127_7500263_1	1379698.RBG1_1C00001G1489	1.383e-62	217.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SYD2_k127_7500263_3	436114.SYO3AOP1_0595	6.441e-31	129.0	COG0558@1|root,COG0558@2|Bacteria,2G47K@200783|Aquificae	200783|Aquificae	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SYD2_k127_7500263_2	1210884.HG799462_gene8164	2.031e-51	192.0	COG1408@1|root,COG1408@2|Bacteria,2J015@203682|Planctomycetes	203682|Planctomycetes	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
SYD2_k127_7500263_0	1123242.JH636435_gene2052	1.187e-122	409.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SYD2_k127_7500263_4	1122619.KB892289_gene362	9.181e-30	126.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,3T26D@506|Alcaligenaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SYD2_k127_7501331_1	1229909.NSED_03370	3.989e-140	458.0	COG1262@1|root,arCOG03517@2157|Archaea,41T1B@651137|Thaumarchaeota	651137|Thaumarchaeota	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
SYD2_k127_7501331_11	1380390.JIAT01000010_gene4278	2.558e-10	73.0	COG1376@1|root,COG1376@2|Bacteria,2HPTN@201174|Actinobacteria,4CR7H@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SYD2_k127_7501331_8	234267.Acid_2191	3.5e-63	229.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4132,HEAT_2
SYD2_k127_7501331_3	357808.RoseRS_0864	1.325e-92	316.0	COG0042@1|root,COG0042@2|Bacteria,2G6XB@200795|Chloroflexi,374WR@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
SYD2_k127_7501331_6	717231.Flexsi_0890	9.89e-77	269.0	COG1077@1|root,COG1077@2|Bacteria,2GEVU@200930|Deferribacteres	200930|Deferribacteres	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SYD2_k127_7501331_9	234267.Acid_7537	5.378e-54	198.0	COG2717@1|root,COG2717@2|Bacteria,3Y58Y@57723|Acidobacteria	57723|Acidobacteria	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
SYD2_k127_7501331_17	562970.Btus_2386	1.57e-06	56.0	COG5581@1|root,COG5581@2|Bacteria	2|Bacteria	M	regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
SYD2_k127_7501331_5	344747.PM8797T_09989	3.602e-80	274.0	COG0500@1|root,COG2226@2|Bacteria,2J0NE@203682|Planctomycetes	203682|Planctomycetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SYD2_k127_7501331_2	1120973.AQXL01000130_gene1193	6.697e-101	364.0	COG1404@1|root,COG1404@2|Bacteria,1UZRQ@1239|Firmicutes,4HEVW@91061|Bacilli	91061|Bacilli	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8,SLH
SYD2_k127_7501331_4	555088.DealDRAFT_1304	4.134e-81	306.0	COG2909@1|root,COG3947@1|root,COG2909@2|Bacteria,COG3947@2|Bacteria,1UIMV@1239|Firmicutes,25GAH@186801|Clostridia	186801|Clostridia	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD
SYD2_k127_7501331_16	1415166.NONO_c02880	6.755e-07	61.0	COG0515@1|root,COG2909@1|root,COG0515@2|Bacteria,COG2909@2|Bacteria,2GIW5@201174|Actinobacteria,4FXQV@85025|Nocardiaceae	201174|Actinobacteria	KLT	Serine threonine-protein kinase pknK	-	-	2.7.11.1	ko:K13419	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12
SYD2_k127_7501331_14	1120985.AUMI01000011_gene347	6.845e-08	61.0	COG0666@1|root,COG0666@2|Bacteria,1V7AY@1239|Firmicutes,4H628@909932|Negativicutes	909932|Negativicutes	S	Ankyrin repeats (3 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
SYD2_k127_7501331_15	1122609.AUGT01000020_gene1045	8.074e-08	62.0	2DRPS@1|root,33CHR@2|Bacteria,2GXSD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7501331_10	1435356.Y013_06200	3.176e-17	85.0	COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria,4FUKE@85025|Nocardiaceae	201174|Actinobacteria	O	Redoxin	ahpE	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
SYD2_k127_7501331_7	247490.KSU1_D0503	2.26e-71	262.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SYD2_k127_7501331_0	1128421.JAGA01000002_gene991	3.652e-182	585.0	COG1793@1|root,COG1793@2|Bacteria,2NPKI@2323|unclassified Bacteria	2|Bacteria	L	ATP dependent DNA ligase C terminal region	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SYD2_k127_7501331_12	269799.Gmet_3543	8.116e-09	62.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SYD2_k127_7501331_19	649349.Lbys_1736	0.0005623	44.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,47KG0@768503|Cytophagia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SYD2_k127_7514970_1	926569.ANT_13240	1.315e-81	276.0	COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SYD2_k127_7514970_0	235909.GK3058	1.456e-150	482.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1WEUI@129337|Geobacillus	91061|Bacilli	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SYD2_k127_7514970_2	234267.Acid_2365	4.057e-65	246.0	COG0841@1|root,COG1538@1|root,COG0841@2|Bacteria,COG1538@2|Bacteria,3Y6DS@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
SYD2_k127_7514970_4	765869.BDW_06185	6.964e-55	203.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,42M23@68525|delta/epsilon subdivisions,2MT12@213481|Bdellovibrionales,2WNU9@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SYD2_k127_7514970_3	243231.GSU2043	1.519e-60	220.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SYD2_k127_7516814_6	926550.CLDAP_01360	2.655e-51	188.0	COG0041@1|root,COG0041@2|Bacteria,2G6JS@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SYD2_k127_7516814_10	1267535.KB906767_gene688	4.734e-08	59.0	2EVWN@1|root,33PAB@2|Bacteria,3Y5UR@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7516814_5	335543.Sfum_0112	1.087e-75	261.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,42SJ9@68525|delta/epsilon subdivisions,2WPBC@28221|Deltaproteobacteria,2MRQE@213462|Syntrophobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SYD2_k127_7516814_7	314345.SPV1_10621	8.812e-39	154.0	COG1611@1|root,COG3350@1|root,COG1611@2|Bacteria,COG3350@2|Bacteria,1R8EU@1224|Proteobacteria	1224|Proteobacteria	S	YHS domain	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	YHS
SYD2_k127_7516814_3	589865.DaAHT2_0467	5.991e-108	366.0	COG0477@1|root,COG2814@2|Bacteria,1QW2F@1224|Proteobacteria,43BTU@68525|delta/epsilon subdivisions,2X74Q@28221|Deltaproteobacteria,2MKZZ@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SYD2_k127_7516814_2	1340493.JNIF01000003_gene4593	1.693e-115	396.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,3Y9F7@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
SYD2_k127_7516814_9	1123508.JH636439_gene803	7.46e-21	108.0	COG3437@1|root,COG3437@2|Bacteria,2IYS1@203682|Planctomycetes	203682|Planctomycetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
SYD2_k127_7516814_4	379066.GAU_2015	6.645e-82	299.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1ZTDZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
SYD2_k127_7516814_1	379066.GAU_2014	4.232e-122	410.0	COG2204@1|root,COG2204@2|Bacteria,1ZUM4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SYD2_k127_7516814_0	767817.Desgi_1433	2.889e-163	529.0	COG0365@1|root,COG0365@2|Bacteria,1UMN9@1239|Firmicutes,25GME@186801|Clostridia	186801|Clostridia	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SYD2_k127_7516814_8	543632.JOJL01000020_gene764	2.676e-34	138.0	COG3483@1|root,COG3483@2|Bacteria,2GNB1@201174|Actinobacteria,4D8E9@85008|Micromonosporales	201174|Actinobacteria	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
SYD2_k127_7531892_1	1267535.KB906767_gene1522	7.055e-119	384.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SYD2_k127_7531892_12	269799.Gmet_3538	2.799e-06	57.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria,43UY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
SYD2_k127_7531892_0	234267.Acid_3371	2.657e-152	496.0	COG0265@1|root,COG0265@2|Bacteria,3Y2WB@57723|Acidobacteria	57723|Acidobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SYD2_k127_7531892_2	1254432.SCE1572_32230	4.568e-118	391.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,42U5B@68525|delta/epsilon subdivisions,2WQVN@28221|Deltaproteobacteria,2YWFF@29|Myxococcales	28221|Deltaproteobacteria	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SYD2_k127_7531892_5	1144275.COCOR_07396	1.14e-43	175.0	COG2898@1|root,COG2898@2|Bacteria,1N1JA@1224|Proteobacteria,437UA@68525|delta/epsilon subdivisions,2WYP1@28221|Deltaproteobacteria,2YU44@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504	2.A.1.3.37	-	-	DUF2156
SYD2_k127_7531892_8	945713.IALB_2992	2.768e-21	101.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SYD2_k127_7531892_3	479434.Sthe_2627	2.279e-114	380.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi,27Y3V@189775|Thermomicrobia	189775|Thermomicrobia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SYD2_k127_7531892_10	525245.HMPREF0044_0355	2.394e-14	81.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4D3TP@85005|Actinomycetales	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SYD2_k127_7531892_9	1118235.CAJH01000047_gene2974	1.53e-15	87.0	28T75@1|root,2ZFFV@2|Bacteria,1RBYB@1224|Proteobacteria,1S6Z2@1236|Gammaproteobacteria,1XCYV@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7531892_7	765420.OSCT_2189	3.501e-24	117.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,2G6NM@200795|Chloroflexi,374VP@32061|Chloroflexia	32061|Chloroflexia	M	Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16
SYD2_k127_7531892_4	682795.AciX8_2195	1.033e-43	164.0	COG1765@1|root,COG1765@2|Bacteria,3Y563@57723|Acidobacteria,2JJUX@204432|Acidobacteriia	204432|Acidobacteriia	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
SYD2_k127_7531892_11	1267535.KB906767_gene3216	1.617e-11	77.0	COG2823@1|root,COG2823@2|Bacteria,3Y3MJ@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
SYD2_k127_7531892_6	639030.JHVA01000001_gene673	2.551e-29	129.0	2A9J8@1|root,30YRM@2|Bacteria,3Y4IZ@57723|Acidobacteria,2JJDB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7541078_11	1226994.AMZB01000105_gene1432	1.256e-43	164.0	COG3386@1|root,COG3386@2|Bacteria,1MX7V@1224|Proteobacteria,1RMQK@1236|Gammaproteobacteria,1YF6H@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	Strictosidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Str_synth
SYD2_k127_7541078_15	941824.TCEL_01034	1.358e-24	113.0	COG1978@1|root,COG1978@2|Bacteria,1UYNY@1239|Firmicutes,24G4U@186801|Clostridia,36E6N@31979|Clostridiaceae	186801|Clostridia	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	prdB	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
SYD2_k127_7541078_14	1382359.JIAL01000001_gene2418	4.408e-29	130.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SYD2_k127_7541078_7	1267535.KB906767_gene1046	5.528e-54	202.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
SYD2_k127_7541078_13	518766.Rmar_0575	2.282e-32	138.0	COG1215@1|root,COG1215@2|Bacteria,4PM5V@976|Bacteroidetes,1FKEK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SYD2_k127_7541078_16	1238182.C882_1599	1.788e-24	117.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,2V85C@28211|Alphaproteobacteria,2JUG7@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SYD2_k127_7541078_6	760192.Halhy_0372	2.946e-62	230.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SYD2_k127_7541078_9	203124.Tery_0022	2.008e-44	168.0	COG0457@1|root,COG0457@2|Bacteria,1GQEX@1117|Cyanobacteria	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7541078_5	318424.EU78_03215	6.038e-78	267.0	COG4122@1|root,COG4122@2|Bacteria,2HU21@201174|Actinobacteria,238TN@1762|Mycobacteriaceae	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SYD2_k127_7541078_17	41431.PCC8801_3410	3.179e-23	109.0	295GN@1|root,2ZAET@2|Bacteria,1G24G@1117|Cyanobacteria,3KHUT@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7541078_19	693661.Arcve_1017	7.622e-12	77.0	COG0529@1|root,arCOG01040@2157|Archaea,2XU4H@28890|Euryarchaeota,2465Z@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
SYD2_k127_7541078_18	797299.HALLA_00275	4.464e-17	94.0	COG0529@1|root,arCOG01040@2157|Archaea,2XU4H@28890|Euryarchaeota,23Y97@183963|Halobacteria	183963|Halobacteria	P	Catalyzes the synthesis of activated sulfate	-	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,CTP_transf_like
SYD2_k127_7541078_2	861299.J421_3595	1.75e-134	447.0	COG0508@1|root,COG0508@2|Bacteria,1ZT7I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SYD2_k127_7541078_12	1121451.DESAM_21635	2.082e-42	158.0	2C82G@1|root,32RK9@2|Bacteria,1MZV5@1224|Proteobacteria,42U4W@68525|delta/epsilon subdivisions,2WQ9S@28221|Deltaproteobacteria,2MCV4@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SYD2_k127_7541078_1	234267.Acid_0353	6.358e-135	438.0	COG0022@1|root,COG0022@2|Bacteria,3Y48G@57723|Acidobacteria	57723|Acidobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SYD2_k127_7541078_3	861299.J421_3598	2.029e-106	360.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	bfmBA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SYD2_k127_7541078_0	378806.STAUR_4671	8.507e-172	550.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2YTYX@29|Myxococcales	28221|Deltaproteobacteria	C	dihydrolipoamide dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SYD2_k127_7541078_10	861299.J421_1647	4.428e-44	165.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SYD2_k127_7541078_8	1121920.AUAU01000009_gene1864	2.176e-46	189.0	COG0457@1|root,COG0457@2|Bacteria,3Y5YE@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7541078_4	886293.Sinac_4730	2.928e-82	279.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SYD2_k127_7550291_0	1210884.HG799465_gene11378	1.755e-43	164.0	COG1778@1|root,COG1778@2|Bacteria,2IZM6@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
SYD2_k127_7550291_2	1158150.KB906242_gene251	6.317e-05	56.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RQGN@1236|Gammaproteobacteria,1WX7M@135613|Chromatiales	135613|Chromatiales	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SYD2_k127_7550291_1	398512.JQKC01000010_gene20	3.463e-25	109.0	2DFIW@1|root,32U5K@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4919)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4919
SYD2_k127_7564901_6	671143.DAMO_1116	1.309e-58	216.0	COG0836@1|root,COG0836@2|Bacteria,2NP3C@2323|unclassified Bacteria	2|Bacteria	M	Mannose-6-phosphate isomerase	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
SYD2_k127_7564901_1	251221.35211731	3.118e-177	563.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	gcd	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
SYD2_k127_7564901_2	861299.J421_1879	9.047e-155	502.0	COG1252@1|root,COG1252@2|Bacteria,1ZT8C@142182|Gemmatimonadetes	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SYD2_k127_7564901_0	234267.Acid_3143	1.208e-246	781.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	glgX	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
SYD2_k127_7564901_8	309799.DICTH_0725	1.906e-06	59.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	Lectin_C,N_methyl,SBP_bac_10,T2SSG
SYD2_k127_7564901_3	204669.Acid345_3201	4.082e-117	385.0	COG0714@1|root,COG0714@2|Bacteria,3Y4G8@57723|Acidobacteria,2JKTE@204432|Acidobacteriia	204432|Acidobacteriia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SYD2_k127_7564901_7	204669.Acid345_0630	1.624e-57	221.0	COG1721@1|root,COG1721@2|Bacteria,3Y5V9@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SYD2_k127_7564901_4	1267535.KB906767_gene3958	3.274e-88	301.0	COG0223@1|root,COG0223@2|Bacteria,3Y32C@57723|Acidobacteria,2JHUK@204432|Acidobacteriia	204432|Acidobacteriia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SYD2_k127_7564901_5	484770.UFO1_3180	1.123e-60	213.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H3AB@909932|Negativicutes	909932|Negativicutes	C	Aldehyde dehydrogenase	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SYD2_k127_757422_0	671143.DAMO_1933	7.39e-265	832.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SYD2_k127_7575456_9	748727.CLJU_c03150	1.03e-45	187.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,36EMG@31979|Clostridiaceae	186801|Clostridia	M	Penicillin-binding Protein	pbpA2	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SYD2_k127_7575456_14	469378.Ccur_03340	4.099e-09	67.0	COG1716@1|root,COG1716@2|Bacteria,2HUFE@201174|Actinobacteria,4CUEU@84998|Coriobacteriia	84998|Coriobacteriia	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
SYD2_k127_7575456_10	1123288.SOV_4c00730	1.127e-44	173.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4H3JJ@909932|Negativicutes	909932|Negativicutes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SYD2_k127_7575456_15	1242864.D187_001134	3.346e-07	62.0	COG3568@1|root,COG3568@2|Bacteria,1QX9Q@1224|Proteobacteria,43C2W@68525|delta/epsilon subdivisions,2X7DI@28221|Deltaproteobacteria,2YXJ1@29|Myxococcales	28221|Deltaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SYD2_k127_7575456_13	1267535.KB906767_gene3024	3.711e-19	92.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	frzZ	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SYD2_k127_7575456_3	204669.Acid345_1883	1.051e-141	457.0	COG2876@1|root,COG2876@2|Bacteria,3Y32G@57723|Acidobacteria,2JIXH@204432|Acidobacteriia	204432|Acidobacteriia	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SYD2_k127_7575456_0	1267535.KB906767_gene1458	6.864e-203	653.0	COG0018@1|root,COG0018@2|Bacteria,3Y35R@57723|Acidobacteria,2JIAM@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SYD2_k127_7575456_7	909663.KI867150_gene2543	1.102e-59	220.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42SWD@68525|delta/epsilon subdivisions,2WK1W@28221|Deltaproteobacteria,2MQCQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SYD2_k127_7575456_6	1174504.AJTN02000033_gene872	1.837e-71	246.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli,1ZAZD@1386|Bacillus	91061|Bacilli	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SYD2_k127_7575456_2	1267535.KB906767_gene3342	3.999e-151	497.0	COG2234@1|root,COG2234@2|Bacteria,3Y3S9@57723|Acidobacteria,2JIF0@204432|Acidobacteriia	204432|Acidobacteriia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SYD2_k127_7575456_11	671143.DAMO_0150	8.781e-30	119.0	2C1SS@1|root,32YN6@2|Bacteria,2NRN5@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7575456_12	671143.DAMO_0151	2.6e-28	115.0	2E90H@1|root,3339X@2|Bacteria,2NS0Z@2323|unclassified Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7575456_1	1382359.JIAL01000001_gene119	3.896e-183	597.0	COG0143@1|root,COG0143@2|Bacteria,3Y2I2@57723|Acidobacteria,2JIC5@204432|Acidobacteriia	204432|Acidobacteriia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
SYD2_k127_7575456_5	414684.RC1_1170	9.887e-77	265.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2TS88@28211|Alphaproteobacteria,2JR2C@204441|Rhodospirillales	204441|Rhodospirillales	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SYD2_k127_7575456_8	1382359.JIAL01000001_gene117	1.825e-58	207.0	COG1666@1|root,COG1666@2|Bacteria,3Y4I3@57723|Acidobacteria,2JJ8P@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
SYD2_k127_7575456_4	234267.Acid_3351	4.258e-83	287.0	COG0142@1|root,COG0142@2|Bacteria,3Y2VJ@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SYD2_k127_7632117_1	1267535.KB906767_gene3956	3.502e-82	280.0	COG0082@1|root,COG0082@2|Bacteria,3Y2Z8@57723|Acidobacteria,2JINW@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SYD2_k127_7632117_2	926566.Terro_0761	1.054e-55	200.0	COG0242@1|root,COG0242@2|Bacteria,3Y4HY@57723|Acidobacteria,2JJ9D@204432|Acidobacteriia	204432|Acidobacteriia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SYD2_k127_7632117_0	1089548.KI783301_gene190	9.534e-148	476.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,3WFDZ@539002|Bacillales incertae sedis	91061|Bacilli	C	Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SYD2_k127_763439_3	1112274.KI911560_gene55	4.324e-51	191.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,2VHKY@28216|Betaproteobacteria,2KMAW@206350|Nitrosomonadales	206350|Nitrosomonadales	O	TIGRFAM sulfate ABC transporter, inner membrane subunit CysT	-	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
SYD2_k127_763439_2	1128421.JAGA01000001_gene2449	1.012e-85	298.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2,TOBE_3
SYD2_k127_763439_0	204669.Acid345_1443	2.91e-135	447.0	COG1012@1|root,COG1012@2|Bacteria,3Y6J2@57723|Acidobacteria,2JMD6@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
SYD2_k127_763439_1	565045.NOR51B_614	6.094e-135	442.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1J4KM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SYD2_k127_763439_5	243090.RB4156	4.884e-06	52.0	COG1427@1|root,COG1427@2|Bacteria,2IYUW@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SYD2_k127_7645071_6	743299.Acife_2251	2.284e-32	134.0	COG0846@1|root,COG0846@2|Bacteria,1NGZY@1224|Proteobacteria	1224|Proteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
SYD2_k127_7645071_7	102125.Xen7305DRAFT_00042720	6.988e-19	93.0	COG2929@1|root,COG2929@2|Bacteria,1G92M@1117|Cyanobacteria,3VNHG@52604|Pleurocapsales	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
SYD2_k127_7645071_5	1396418.BATQ01000117_gene4548	6.154e-40	168.0	COG4745@1|root,COG4745@2|Bacteria,46T45@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SYD2_k127_7645071_3	525904.Tter_0360	2.699e-43	181.0	COG5427@1|root,COG5427@2|Bacteria	2|Bacteria	M	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7645071_2	234267.Acid_0903	9.361e-66	230.0	COG0233@1|root,COG0233@2|Bacteria,3Y4AP@57723|Acidobacteria	57723|Acidobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SYD2_k127_7645071_0	468059.AUHA01000002_gene628	1.262e-92	310.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1IPN7@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SYD2_k127_7645071_1	1120973.AQXL01000128_gene2824	6.648e-82	277.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,27828@186823|Alicyclobacillaceae	91061|Bacilli	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SYD2_k127_7645071_4	682795.AciX8_4594	9.659e-42	159.0	COG0052@1|root,COG0052@2|Bacteria,3Y3K2@57723|Acidobacteria,2JI0A@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SYD2_k127_7693726_0	204669.Acid345_2140	1.302e-122	405.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,3Y466@57723|Acidobacteria,2JHTM@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SYD2_k127_7693726_1	391625.PPSIR1_35247	6.957e-109	364.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YZ2Q@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SYD2_k127_7693726_2	1382359.JIAL01000001_gene1834	3.543e-56	209.0	COG2234@1|root,COG2234@2|Bacteria,3Y406@57723|Acidobacteria,2JIRZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SYD2_k127_7693726_3	1121441.AUCX01000009_gene2470	1.382e-44	166.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2X5PR@28221|Deltaproteobacteria,2MBC8@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SYD2_k127_7693726_4	765869.BDW_11285	7.591e-43	163.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,42PJP@68525|delta/epsilon subdivisions,2MTGD@213481|Bdellovibrionales,2WJI0@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	membrane protein, TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SYD2_k127_7739730_1	1499967.BAYZ01000167_gene6756	1.121e-28	120.0	COG0429@1|root,COG0429@2|Bacteria	2|Bacteria	S	poly(3-hydroxybutyrate) depolymerase activity	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
SYD2_k127_7739730_0	1267535.KB906767_gene5522	1.427e-168	576.0	COG1196@1|root,COG1196@2|Bacteria,3Y2W1@57723|Acidobacteria,2JHJF@204432|Acidobacteriia	204432|Acidobacteriia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SYD2_k127_7792514_4	479434.Sthe_1898	1.896e-33	136.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi,27YFE@189775|Thermomicrobia	189775|Thermomicrobia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SYD2_k127_7792514_2	373903.Hore_14640	2.292e-87	299.0	COG0330@1|root,COG0330@2|Bacteria,1W711@1239|Firmicutes,25IRK@186801|Clostridia,3WC5Y@53433|Halanaerobiales	186801|Clostridia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SYD2_k127_7792514_1	1267533.KB906737_gene1877	9.358e-94	324.0	COG0154@1|root,COG0154@2|Bacteria,3Y41H@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SYD2_k127_7792514_3	1122927.KB895422_gene3825	8.109e-49	182.0	COG2009@1|root,COG2009@2|Bacteria,1TQUI@1239|Firmicutes,4HBX0@91061|Bacilli,26SKM@186822|Paenibacillaceae	91061|Bacilli	C	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SYD2_k127_7792514_0	1123252.ATZF01000008_gene28	8.404e-140	447.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HBVG@91061|Bacilli,27AWM@186824|Thermoactinomycetaceae	91061|Bacilli	C	Fumarate reductase flavoprotein C-term	sdhA	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05640	FAD_binding_2,Succ_DH_flav_C
SYD2_k127_7824224_3	1094715.CM001373_gene1274	8.644e-61	224.0	COG0332@1|root,COG0332@2|Bacteria	2|Bacteria	I	beta-ketoacyl-acyl-carrier-protein synthase III activity	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SYD2_k127_7824224_6	316056.RPC_2152	0.0003156	48.0	2EBJP@1|root,335K4@2|Bacteria,1NCJY@1224|Proteobacteria,2UI9B@28211|Alphaproteobacteria,3K1BH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7824224_1	1045009.AFXQ01000016_gene181	1.718e-94	322.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,1W7G0@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
SYD2_k127_7824224_4	401053.AciPR4_2475	4.75e-41	158.0	2B1QU@1|root,31U6H@2|Bacteria,3Y5EE@57723|Acidobacteria,2JJUF@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF3224)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3224
SYD2_k127_7824224_0	234267.Acid_5430	5.484e-223	711.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y6TN@57723|Acidobacteria	57723|Acidobacteria	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SYD2_k127_7824224_5	1121931.AUHG01000010_gene507	1.963e-31	129.0	2DEWP@1|root,2ZPJE@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SYD2_k127_7824224_2	1499967.BAYZ01000009_gene5383	3.738e-89	304.0	COG1653@1|root,COG1653@2|Bacteria,2NP9E@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SYD2_k127_7853532_5	1198114.AciX9_1694	4.766e-07	61.0	COG0457@1|root,COG4796@1|root,COG0457@2|Bacteria,COG4796@2|Bacteria,3Y2G2@57723|Acidobacteria,2JHZH@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,Secretin,Secretin_N
SYD2_k127_7853532_2	1382359.JIAL01000001_gene2215	7.599e-28	121.0	COG2165@1|root,COG2165@2|Bacteria,3Y4RJ@57723|Acidobacteria,2JJB4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
SYD2_k127_7853532_1	204669.Acid345_1999	2.304e-32	131.0	COG2165@1|root,COG2165@2|Bacteria,3Y4ZX@57723|Acidobacteria,2JJN5@204432|Acidobacteriia	204432|Acidobacteriia	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
SYD2_k127_7853532_4	404380.Gbem_1280	1.183e-07	63.0	COG4972@1|root,COG4972@2|Bacteria,1NUYA@1224|Proteobacteria,42ZJI@68525|delta/epsilon subdivisions,2WV3A@28221|Deltaproteobacteria,43UN3@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Pilus assembly protein	pulM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SYD2_k127_7853532_0	379066.GAU_2442	9.297e-37	146.0	COG1595@1|root,COG1595@2|Bacteria,1ZT3B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SYD2_k127_7853532_3	338966.Ppro_2663	4.041e-26	115.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42W7K@68525|delta/epsilon subdivisions,2WRU7@28221|Deltaproteobacteria,43VUJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SYD2_k127_7870716_2	204669.Acid345_2015	4.079e-29	124.0	COG2006@1|root,COG2006@2|Bacteria,3Y7N1@57723|Acidobacteria,2JNKP@204432|Acidobacteriia	204432|Acidobacteriia	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SYD2_k127_7870716_0	452637.Oter_4609	6.892e-288	908.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SYD2_k127_7870716_1	861299.J421_1696	2.528e-214	689.0	COG2866@1|root,COG2866@2|Bacteria,1ZUNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SYD2_k127_7874289_3	401053.AciPR4_0800	7.545e-79	271.0	COG0606@1|root,COG0606@2|Bacteria,3Y3JA@57723|Acidobacteria,2JI3F@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM Magnesium chelatase, ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SYD2_k127_7874289_5	338963.Pcar_2042	3.599e-63	238.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,43S23@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Lytic transglycosylase catalytic	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
SYD2_k127_7874289_0	289376.THEYE_A0859	4.951e-301	944.0	COG0466@1|root,COG0466@2|Bacteria,3J0DQ@40117|Nitrospirae	40117|Nitrospirae	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SYD2_k127_7874289_13	932678.THERU_04765	1.418e-13	77.0	COG0071@1|root,COG0071@2|Bacteria,2G4AZ@200783|Aquificae	200783|Aquificae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SYD2_k127_7874289_4	401053.AciPR4_0863	1.948e-63	220.0	COG1327@1|root,COG1327@2|Bacteria,3Y4GA@57723|Acidobacteria,2JJ32@204432|Acidobacteriia	204432|Acidobacteriia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SYD2_k127_7874289_10	243231.GSU1488	2.341e-24	117.0	COG0392@1|root,COG0392@2|Bacteria,1N7DR@1224|Proteobacteria,42N4R@68525|delta/epsilon subdivisions,2WS5Z@28221|Deltaproteobacteria,43TTU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SYD2_k127_7874289_6	234267.Acid_0793	1.675e-47	177.0	COG1595@1|root,COG1595@2|Bacteria,3Y4HK@57723|Acidobacteria	57723|Acidobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SYD2_k127_7874289_14	1267535.KB906767_gene1042	5.308e-05	54.0	COG5662@1|root,COG5662@2|Bacteria,3Y4S0@57723|Acidobacteria	57723|Acidobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SYD2_k127_7874289_12	1382359.JIAL01000001_gene781	9.695e-14	80.0	2DMGW@1|root,32REM@2|Bacteria,3Y4XX@57723|Acidobacteria,2JJER@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-B_box
SYD2_k127_7874289_7	363253.LI0920	1.853e-41	163.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2M8GP@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SYD2_k127_7874289_2	880073.Calab_2857	6.038e-138	467.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	DUF2808,Peptidase_S46
SYD2_k127_7874289_9	360911.EAT1b_1944	7.696e-25	106.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli	91061|Bacilli	K	Cold-Shock Protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SYD2_k127_7874289_8	204669.Acid345_0269	4.453e-33	137.0	2ENGH@1|root,33G40@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7874289_11	1318628.MARLIPOL_07224	1.714e-20	104.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria,465V0@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235,RHS,RHS_repeat
SYD2_k127_7874289_1	1318628.MARLIPOL_07224	5.901e-145	500.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria,465V0@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235,RHS,RHS_repeat
SYD2_k127_7902582_0	204669.Acid345_4661	3.664e-204	654.0	COG0539@1|root,COG0539@2|Bacteria,3Y3DA@57723|Acidobacteria,2JHS3@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal protein S1	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SYD2_k127_7902582_3	204669.Acid345_4105	3.196e-32	129.0	COG0776@1|root,COG0776@2|Bacteria,3Y56V@57723|Acidobacteria,2JJMF@204432|Acidobacteriia	204432|Acidobacteriia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SYD2_k127_7902582_1	234267.Acid_4300	9.837e-52	187.0	COG0537@1|root,COG0537@2|Bacteria,3Y4CN@57723|Acidobacteria	57723|Acidobacteria	FG	PFAM Histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SYD2_k127_7902582_2	880072.Desac_0015	4.686e-48	177.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42NA6@68525|delta/epsilon subdivisions,2WIMU@28221|Deltaproteobacteria,2MQ6V@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SYD2_k127_7911723_3	237368.SCABRO_03745	3.169e-192	612.0	COG1012@1|root,COG1012@2|Bacteria,2IXV2@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.39	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SYD2_k127_7911723_11	324925.Ppha_0327	1.442e-67	235.0	COG0551@1|root,COG0551@2|Bacteria,1FF54@1090|Chlorobi	1090|Chlorobi	L	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7911723_8	1356852.N008_00500	3.285e-120	393.0	28HGI@1|root,2Z7SC@2|Bacteria,4NJUF@976|Bacteroidetes,47PDE@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7911723_0	497964.CfE428DRAFT_1607	0.0	1287.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SYD2_k127_7911723_19	1170562.Cal6303_0902	4.025e-11	69.0	2EE59@1|root,337ZW@2|Bacteria,1G955@1117|Cyanobacteria,1HNGZ@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7911723_6	234267.Acid_3557	9.663e-141	454.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SYD2_k127_7911723_17	1289135.A966_07534	1.101e-28	124.0	COG0652@1|root,COG0652@2|Bacteria,2J58N@203691|Spirochaetes	203691|Spirochaetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
SYD2_k127_7911723_15	771875.Ferpe_1363	8.235e-51	184.0	COG1490@1|root,COG1490@2|Bacteria,2GCYQ@200918|Thermotogae	200918|Thermotogae	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SYD2_k127_7911723_10	649638.Trad_2700	2.64e-72	250.0	COG4221@1|root,COG4221@2|Bacteria,1WIDQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SYD2_k127_7911723_4	234267.Acid_7720	7.711e-171	549.0	COG0064@1|root,COG0064@2|Bacteria,3Y2TJ@57723|Acidobacteria	57723|Acidobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SYD2_k127_7911723_18	1198114.AciX9_2795	4.896e-28	130.0	COG2304@1|root,COG2304@2|Bacteria,3Y44P@57723|Acidobacteria,2JIT1@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SYD2_k127_7911723_9	1267535.KB906767_gene3137	4.318e-115	399.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
SYD2_k127_7911723_13	1089553.Tph_c15800	5.866e-55	204.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,42FXA@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SYD2_k127_7911723_12	1125863.JAFN01000001_gene2855	7.655e-67	240.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,42PIH@68525|delta/epsilon subdivisions,2WJH2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	-	-	-	-	-	-	-	-	-	FecCD
SYD2_k127_7911723_14	555079.Toce_1426	9.759e-53	201.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,24AKE@186801|Clostridia,42FIR@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SYD2_k127_7911723_7	1267535.KB906767_gene4340	5.222e-129	421.0	COG0182@1|root,COG0182@2|Bacteria,3Y2TR@57723|Acidobacteria,2JHZX@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SYD2_k127_7911723_1	1174528.JH992893_gene5975	7.76e-244	765.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1G15G@1117|Cyanobacteria,1JHXK@1189|Stigonemataceae	1117|Cyanobacteria	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SYD2_k127_7911723_5	329726.AM1_6319	2.359e-156	501.0	COG1023@1|root,COG1023@2|Bacteria,1G07T@1117|Cyanobacteria	1117|Cyanobacteria	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SYD2_k127_7911723_2	1267535.KB906767_gene3266	7.507e-223	701.0	COG0364@1|root,COG0364@2|Bacteria,3Y2JZ@57723|Acidobacteria,2JHKE@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SYD2_k127_7929561_0	497965.Cyan7822_3673	5.184e-53	192.0	COG1104@1|root,COG1104@2|Bacteria,1G0D5@1117|Cyanobacteria,3KG9T@43988|Cyanothece	1117|Cyanobacteria	H	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SYD2_k127_7929561_1	203119.Cthe_2151	2.729e-48	196.0	2DCRV@1|root,2ZF3U@2|Bacteria,1UIUF@1239|Firmicutes,25ES9@186801|Clostridia,3WSJ4@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7931224_2	204669.Acid345_0162	1.515e-46	177.0	COG0531@1|root,COG0531@2|Bacteria,3Y2RG@57723|Acidobacteria,2JHMH@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SYD2_k127_7931224_0	264462.Bd3456	6.15e-91	310.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2MTWP@213481|Bdellovibrionales,2WMJ2@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SYD2_k127_7931224_1	383372.Rcas_0336	2.245e-80	284.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SYD2_k127_793428_0	398767.Glov_2172	4.038e-94	316.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
SYD2_k127_793428_1	1242864.D187_010069	7.46e-69	252.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
SYD2_k127_793428_3	1869.MB27_30450	1.441e-30	130.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria	201174|Actinobacteria	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SYD2_k127_793428_2	871963.Desdi_2842	2.619e-34	145.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia,2629Q@186807|Peptococcaceae	186801|Clostridia	M	PFAM Transglycosylase SLT domain	yjbJ	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
SYD2_k127_793428_4	768066.HELO_2212	2.245e-14	86.0	COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,1XP8V@135619|Oceanospirillales	135619|Oceanospirillales	S	ErfK YbiS YcfS YnhG	-	-	-	ko:K16291	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	YkuD
SYD2_k127_7941938_2	243231.GSU2335	3.464e-10	63.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SYD2_k127_7941938_1	743722.Sph21_2115	1.512e-19	95.0	COG3467@1|root,COG3467@2|Bacteria,4NQFR@976|Bacteroidetes,1ITPB@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SYD2_k127_7941938_0	1382356.JQMP01000003_gene1584	1.558e-316	993.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,27XKK@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SYD2_k127_7943685_8	1235803.C825_02312	1.015e-15	92.0	2CB8C@1|root,33T5I@2|Bacteria,4P0N1@976|Bacteroidetes,2FX4B@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7943685_7	1111069.TCCBUS3UF1_8820	2.345e-17	85.0	COG1254@1|root,COG1254@2|Bacteria,1WK7T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SYD2_k127_7943685_1	1047013.AQSP01000052_gene2600	6.449e-89	302.0	COG4152@1|root,COG4152@2|Bacteria,2NQE2@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4162)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SYD2_k127_7943685_2	1047013.AQSP01000052_gene2599	2.322e-73	263.0	COG1668@1|root,COG1668@2|Bacteria,2NPCQ@2323|unclassified Bacteria	2|Bacteria	CP	ABC-2 family transporter protein	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SYD2_k127_7943685_6	525897.Dbac_1617	4.147e-21	101.0	COG1437@1|root,COG1437@2|Bacteria,1N326@1224|Proteobacteria,42U83@68525|delta/epsilon subdivisions,2WQQR@28221|Deltaproteobacteria,2MBY3@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	PFAM Adenylate cyclase	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
SYD2_k127_7943685_3	382464.ABSI01000010_gene3594	4.647e-37	148.0	COG1595@1|root,COG1595@2|Bacteria,46SZG@74201|Verrucomicrobia,2IUFS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SYD2_k127_7943685_10	682795.AciX8_0800	1.316e-08	66.0	COG1729@1|root,COG1729@2|Bacteria,3Y4ME@57723|Acidobacteria,2JJA9@204432|Acidobacteriia	204432|Acidobacteriia	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
SYD2_k127_7943685_5	246197.MXAN_1138	2.253e-28	128.0	COG1988@1|root,COG1988@2|Bacteria,1RA9E@1224|Proteobacteria,438D4@68525|delta/epsilon subdivisions,2X3NA@28221|Deltaproteobacteria,2YWMP@29|Myxococcales	28221|Deltaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
SYD2_k127_7943685_0	1340493.JNIF01000003_gene1969	3.164e-116	384.0	COG0189@1|root,COG0189@2|Bacteria,3Y37D@57723|Acidobacteria	57723|Acidobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7943685_4	720554.Clocl_2649	8.745e-34	138.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,3WIW4@541000|Ruminococcaceae	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SYD2_k127_7943685_11	67352.JODS01000003_gene1929	7.782e-05	53.0	2DTGA@1|root,33K7S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SYD2_k127_7943685_9	638303.Thal_1499	3.825e-14	86.0	COG0265@1|root,COG0265@2|Bacteria,2G3MU@200783|Aquificae	200783|Aquificae	M	PFAM peptidase S1 and S6 chymotrypsin Hap	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SYD2_k127_7957258_8	679926.Mpet_2610	3.102e-78	271.0	COG0548@1|root,arCOG00862@2157|Archaea,2XTW9@28890|Euryarchaeota,2N912@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SYD2_k127_7957258_5	767434.Fraau_2115	1.376e-95	323.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1S7AW@1236|Gammaproteobacteria,1X35E@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.9	ko:K09065	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SYD2_k127_7957258_12	653733.Selin_0993	6.096e-32	132.0	COG3169@1|root,COG3169@2|Bacteria	2|Bacteria	S	Protein conserved in bacteria	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
SYD2_k127_7957258_16	1123073.KB899242_gene1134	2.643e-14	75.0	2EFVT@1|root,339N0@2|Bacteria,1MZTF@1224|Proteobacteria,1S950@1236|Gammaproteobacteria,1X8KN@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7957258_4	518766.Rmar_0947	3.018e-102	346.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1FJWU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SYD2_k127_7957258_7	444158.MmarC6_0836	3.938e-81	282.0	COG0002@1|root,arCOG00495@2157|Archaea,2XTC1@28890|Euryarchaeota,23Q0I@183939|Methanococci	183939|Methanococci	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SYD2_k127_7957258_9	518766.Rmar_0949	1.719e-72	259.0	COG1763@1|root,COG1763@2|Bacteria,4PM6G@976|Bacteroidetes,1FK05@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Mo-molybdopterin cofactor biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_7957258_0	667014.Thein_0557	3.278e-178	566.0	COG0137@1|root,COG0137@2|Bacteria,2GGZY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SYD2_k127_7957258_13	1347392.CCEZ01000043_gene484	1.308e-20	96.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,36IRA@31979|Clostridiaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SYD2_k127_7957258_1	155864.EDL933_5296	5.302e-157	507.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,3XMS6@561|Escherichia	1236|Gammaproteobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,4.3.2.1	ko:K01755,ko:K14681	ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230	M00028,M00029,M00844,M00845	R00259,R01086	RC00004,RC00064,RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Acetyltransf_1,Lyase_1
SYD2_k127_7957258_2	448385.sce7696	1.043e-130	431.0	COG1404@1|root,COG1404@2|Bacteria,1PEJJ@1224|Proteobacteria,438RE@68525|delta/epsilon subdivisions,2X3YD@28221|Deltaproteobacteria,2YXKA@29|Myxococcales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SYD2_k127_7957258_3	1163617.SCD_n00323	4.869e-108	359.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2WGFK@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29,1.1.1.399,1.1.1.95	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020,M00346	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SYD2_k127_7957258_11	926550.CLDAP_25090	4.461e-36	141.0	COG0454@1|root,COG0456@2|Bacteria,2G95N@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
SYD2_k127_7957258_17	1198114.AciX9_1303	5.477e-14	83.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SYD2_k127_7957258_14	204669.Acid345_0034	2.646e-20	93.0	COG2331@1|root,COG2331@2|Bacteria,3Y5KN@57723|Acidobacteria,2JJW0@204432|Acidobacteriia	204432|Acidobacteriia	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SYD2_k127_7957258_6	880072.Desac_0720	8.261e-95	337.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SYD2_k127_7957258_18	84588.SYNW1762	4.805e-13	80.0	COG1266@1|root,COG1266@2|Bacteria,1G0ZJ@1117|Cyanobacteria,1GZ8P@1129|Synechococcus	1117|Cyanobacteria	S	metal-dependent membrane protease	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SYD2_k127_7957258_10	926550.CLDAP_29020	5.106e-40	166.0	COG1233@1|root,COG1233@2|Bacteria,2G5U1@200795|Chloroflexi	200795|Chloroflexi	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SYD2_k127_7957258_15	1122138.AQUZ01000011_gene5003	9.898e-17	83.0	COG1725@1|root,COG1725@2|Bacteria,2IQEW@201174|Actinobacteria,4DSDY@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
SYD2_k127_7965976_2	234267.Acid_0746	9.724e-53	211.0	COG2911@1|root,COG2911@2|Bacteria,3Y3A6@57723|Acidobacteria	57723|Acidobacteria	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
SYD2_k127_7965976_1	1267535.KB906767_gene3597	6.263e-54	218.0	COG4775@1|root,COG4775@2|Bacteria,3Y2RF@57723|Acidobacteria,2JHK5@204432|Acidobacteriia	204432|Acidobacteriia	M	surface antigen variable number	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
SYD2_k127_7965976_6	1033734.CAET01000004_gene3786	8.405e-06	57.0	COG0760@1|root,COG0760@2|Bacteria,1V831@1239|Firmicutes,4HIND@91061|Bacilli,1ZCCR@1386|Bacillus	91061|Bacilli	O	COG0760 Parvulin-like peptidyl-prolyl isomerase	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3
SYD2_k127_7965976_3	426114.THI_2270	7.681e-42	166.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria,1KK0K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SYD2_k127_7965976_0	682795.AciX8_3921	4.368e-138	469.0	COG0744@1|root,COG0744@2|Bacteria,3Y42I@57723|Acidobacteria,2JI7Q@204432|Acidobacteriia	204432|Acidobacteriia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SYD2_k127_7965976_4	247490.KSU1_C1660	3.256e-20	97.0	COG1943@1|root,COG1943@2|Bacteria,2J110@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SYD2_k127_7965976_5	906968.Trebr_1167	2.095e-06	50.0	COG0736@1|root,COG0736@2|Bacteria,2J8AA@203691|Spirochaetes	203691|Spirochaetes	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SYD2_k127_8005127_4	204669.Acid345_1590	1.448e-56	210.0	COG4191@1|root,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria,2JING@204432|Acidobacteriia	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02668,ko:K07708	ko02020,map02020	M00497,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg,RsbRD_N
SYD2_k127_8005127_6	1122138.AQUZ01000019_gene8171	5.506e-19	102.0	COG1520@1|root,COG4733@1|root,COG1520@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,PQQ_2,SLH
SYD2_k127_8005127_0	204669.Acid345_1066	1.411e-138	464.0	COG1404@1|root,COG1409@1|root,COG3055@1|root,COG3291@1|root,COG3386@1|root,COG1404@2|Bacteria,COG1409@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,3Y3S3@57723|Acidobacteria,2JMMV@204432|Acidobacteriia	204432|Acidobacteriia	GO	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	ASH
SYD2_k127_8005127_3	1267535.KB906767_gene4659	8.937e-117	383.0	COG0266@1|root,COG0266@2|Bacteria,3Y71J@57723|Acidobacteria,2JKGK@204432|Acidobacteriia	204432|Acidobacteriia	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SYD2_k127_8005127_5	1267533.KB906735_gene4542	6.76e-39	157.0	COG2885@1|root,COG2885@2|Bacteria,3Y7Y8@57723|Acidobacteria,2JMX3@204432|Acidobacteriia	204432|Acidobacteriia	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SYD2_k127_8005127_2	1396141.BATP01000003_gene5228	2.072e-135	443.0	COG0451@1|root,COG0451@2|Bacteria,46XPQ@74201|Verrucomicrobia,2IWC3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_8005127_1	1123060.JONP01000004_gene704	9.901e-137	447.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,2U1N0@28211|Alphaproteobacteria,2JW2Q@204441|Rhodospirillales	204441|Rhodospirillales	C	ATP ADP translocase	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SYD2_k127_8012561_1	485913.Krac_7830	9.94e-113	376.0	COG0438@1|root,COG0438@2|Bacteria,2G683@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SYD2_k127_8012561_8	278963.ATWD01000001_gene4303	0.000123	48.0	2CBGA@1|root,32RQS@2|Bacteria,3Y57E@57723|Acidobacteria,2JJT7@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_8012561_0	1380763.BG53_14175	6.524e-242	760.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,4HE3C@91061|Bacilli,26Q8T@186822|Paenibacillaceae	91061|Bacilli	H	Belongs to the UbiD family	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
SYD2_k127_8012561_2	349521.HCH_01549	2.236e-64	231.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1T8Z2@1236|Gammaproteobacteria,1XQMP@135619|Oceanospirillales	135619|Oceanospirillales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
SYD2_k127_8012561_4	1286631.X805_30960	7.781e-32	136.0	COG1404@1|root,COG1520@1|root,COG5640@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K14645,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PPC,PQQ_2,Peptidase_S8,SBBP
SYD2_k127_8012561_5	379066.GAU_3293	1.659e-29	124.0	294EW@1|root,2ZRUR@2|Bacteria,1ZV2S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
SYD2_k127_8012561_3	859657.RPSI07_0971	7.385e-34	132.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2VN9Y@28216|Betaproteobacteria,1K6AS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SYD2_k127_8041727_5	1250232.JQNJ01000001_gene1910	2.265e-07	54.0	2CWY1@1|root,32T0M@2|Bacteria,4P319@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_8041727_0	1379270.AUXF01000005_gene474	1.643e-127	435.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZSZA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SYD2_k127_8041727_1	1120973.AQXL01000068_gene19	1.109e-65	232.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HB73@91061|Bacilli,2788T@186823|Alicyclobacillaceae	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	fadB	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K01715,ko:K13767	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R03026,R04170,R04738,R04740,R04744,R04746	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SYD2_k127_8041727_6	1346791.M529_09315	0.0002519	53.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TRTE@28211|Alphaproteobacteria,2K0PD@204457|Sphingomonadales	204457|Sphingomonadales	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SYD2_k127_8041727_2	1123242.JH636434_gene4898	4.311e-23	108.0	COG0642@1|root,COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,2IX8Z@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
SYD2_k127_8042116_2	398767.Glov_1868	2.636e-53	200.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,42ME9@68525|delta/epsilon subdivisions,2WKF0@28221|Deltaproteobacteria,43T7S@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SYD2_k127_8042116_1	243233.MCA2183	1.241e-79	269.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,1S3N1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SYD2_k127_8042116_0	1340434.AXVA01000012_gene2953	2.109e-114	385.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,4HBJ1@91061|Bacilli	91061|Bacilli	C	Conserved carboxylase domain	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
SYD2_k127_8042116_3	1297742.A176_06772	1.766e-45	169.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,434AF@68525|delta/epsilon subdivisions,2X23S@28221|Deltaproteobacteria,2YVSR@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SYD2_k127_892162_12	234267.Acid_5446	2.646e-20	93.0	COG0665@1|root,COG0665@2|Bacteria,3Y3W7@57723|Acidobacteria	57723|Acidobacteria	E	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SYD2_k127_892162_1	1123248.KB893327_gene788	8.068e-107	353.0	COG0258@1|root,COG0258@2|Bacteria	2|Bacteria	L	nuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SYD2_k127_892162_13	394221.Mmar10_0732	3.232e-13	81.0	COG1266@1|root,COG1266@2|Bacteria,1MYYZ@1224|Proteobacteria,2UBB3@28211|Alphaproteobacteria,43Y1Z@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SYD2_k127_892162_10	485913.Krac_3321	7.457e-31	129.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	FA_hydroxylase,Polyketide_cyc2
SYD2_k127_892162_11	69395.JQLZ01000006_gene2054	3.041e-21	101.0	COG5646@1|root,COG5646@2|Bacteria,1NKMZ@1224|Proteobacteria,2UJHW@28211|Alphaproteobacteria,2KJ5I@204458|Caulobacterales	204458|Caulobacterales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SYD2_k127_892162_2	65497.JODV01000004_gene1483	2.867e-89	301.0	COG4912@1|root,COG4912@2|Bacteria,2ID3C@201174|Actinobacteria,4E7JU@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SYD2_k127_892162_8	1380355.JNIJ01000005_gene2647	2.137e-42	161.0	COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,2U5A4@28211|Alphaproteobacteria,3JY25@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	MA20_04095	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
SYD2_k127_892162_4	331869.BAL199_16858	5.02e-62	217.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2U993@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SYD2_k127_892162_5	404589.Anae109_2831	7.657e-59	206.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SYD2_k127_892162_6	404589.Anae109_1540	5.461e-52	186.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SYD2_k127_892162_3	1487953.JMKF01000086_gene5566	7.991e-65	226.0	2BUPP@1|root,32Q0P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772
SYD2_k127_892162_7	272134.KB731324_gene6666	7.484e-49	177.0	COG3795@1|root,COG3795@2|Bacteria,1G6M3@1117|Cyanobacteria,1HBWD@1150|Oscillatoriales	1117|Cyanobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SYD2_k127_892162_9	1278073.MYSTI_05295	2.063e-35	138.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,432ET@68525|delta/epsilon subdivisions,2X94U@28221|Deltaproteobacteria,2Z1Y0@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SYD2_k127_892162_14	997350.HMPREF9129_0347	6.021e-05	50.0	COG1366@1|root,COG1366@2|Bacteria,1TU2B@1239|Firmicutes,24ST7@186801|Clostridia,22HZ7@1570339|Peptoniphilaceae	186801|Clostridia	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SYD2_k127_892162_0	272134.KB731325_gene694	3.545e-157	505.0	COG4941@1|root,COG4941@2|Bacteria,1G1YQ@1117|Cyanobacteria,1H7AG@1150|Oscillatoriales	1117|Cyanobacteria	K	RNA polymerase, sigma subunit, ECF family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SYD2_k127_906783_13	487796.Flav2ADRAFT_1527	6.616e-14	85.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SYD2_k127_906783_15	487796.Flav2ADRAFT_1528	8.144e-12	71.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	-	-	-	-	-	-	-	-	-	STAS
SYD2_k127_906783_4	204669.Acid345_2866	9.775e-54	205.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,3Y52R@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_906783_1	316056.RPC_4894	1.438e-164	522.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,3JVP4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SYD2_k127_906783_5	163908.KB235896_gene2766	1.282e-43	160.0	COG4680@1|root,COG4680@2|Bacteria,1G7BW@1117|Cyanobacteria	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
SYD2_k127_906783_10	756067.MicvaDRAFT_0374	6.397e-22	105.0	COG5499@1|root,COG5499@2|Bacteria,1G95W@1117|Cyanobacteria,1HDGB@1150|Oscillatoriales	1117|Cyanobacteria	K	transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
SYD2_k127_906783_0	1267534.KB906758_gene2265	2.087e-302	940.0	COG2936@1|root,COG2936@2|Bacteria,3Y33N@57723|Acidobacteria	57723|Acidobacteria	S	Hydrolase CocE NonD family	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
SYD2_k127_906783_9	1444310.JANV01000115_gene4517	3.41e-26	109.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,1ZHWN@1386|Bacillus	91061|Bacilli	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SYD2_k127_906783_11	378806.STAUR_7589	3.545e-17	86.0	COG1366@1|root,COG1366@2|Bacteria,1NJGJ@1224|Proteobacteria	1224|Proteobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
SYD2_k127_906783_14	1437608.BBIA_0897	1.958e-12	69.0	COG3655@1|root,COG3655@2|Bacteria,2GQZM@201174|Actinobacteria,4D1EQ@85004|Bifidobacteriales	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
SYD2_k127_906783_2	269799.Gmet_2971	2.453e-154	503.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,43S64@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SYD2_k127_906783_3	215803.DB30_1351	2.325e-85	293.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SYD2_k127_906783_12	1267534.KB906760_gene1308	2.022e-16	88.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SYD2_k127_906783_8	1283299.AUKG01000002_gene4124	2.065e-28	131.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4CPGP@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SYD2_k127_906783_6	1122939.ATUD01000013_gene874	5.858e-42	172.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CQ6E@84995|Rubrobacteria	84995|Rubrobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SYD2_k127_906783_7	1121423.JONT01000013_gene366	1.719e-35	145.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia,26015@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
SYD2_k127_909265_5	1121920.AUAU01000015_gene1127	1.451e-23	108.0	COG2385@1|root,COG2385@2|Bacteria,3Y370@57723|Acidobacteria	57723|Acidobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SPOR,SpoIID
SYD2_k127_909265_2	234267.Acid_1297	9.833e-76	265.0	COG0324@1|root,COG0324@2|Bacteria,3Y3CE@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SYD2_k127_909265_6	1267533.KB906733_gene3525	2.948e-21	101.0	COG1923@1|root,COG1923@2|Bacteria,3Y59T@57723|Acidobacteria,2JJSQ@204432|Acidobacteriia	204432|Acidobacteriia	S	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
SYD2_k127_909265_3	351607.Acel_1971	3.037e-55	201.0	COG0125@1|root,COG0477@1|root,COG0125@2|Bacteria,COG2814@2|Bacteria,2GNTI@201174|Actinobacteria,4ES48@85013|Frankiales	201174|Actinobacteria	EFGP	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_3,Thymidylate_kin
SYD2_k127_909265_4	338963.Pcar_1692	3.435e-50	193.0	COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria,43RXK@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit, C terminal	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SYD2_k127_909265_0	1121468.AUBR01000029_gene1577	7.834e-132	431.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,42FDK@68295|Thermoanaerobacterales	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
SYD2_k127_909265_1	1267533.KB906733_gene3587	1.256e-78	280.0	COG0750@1|root,COG0750@2|Bacteria,3Y2KN@57723|Acidobacteria,2JI1B@204432|Acidobacteriia	204432|Acidobacteriia	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SYD2_k127_91732_1	1105031.HMPREF1141_2120	1.13e-59	213.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,36EPV@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SYD2_k127_91732_2	378806.STAUR_6365	2.143e-39	156.0	COG1842@1|root,COG1842@2|Bacteria,1NNUD@1224|Proteobacteria,438WP@68525|delta/epsilon subdivisions,2X9RW@28221|Deltaproteobacteria,2YY15@29|Myxococcales	28221|Deltaproteobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SYD2_k127_91732_3	1278073.MYSTI_06291	2.208e-19	98.0	2EDTI@1|root,337NU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_91732_0	428125.CLOLEP_00746	2.649e-140	477.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,3WGZ6@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
SYD2_k127_92719_1	93220.LV28_03815	4.687e-86	296.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2WFNZ@28216|Betaproteobacteria,1KI4E@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	OCD_Mu_crystall
SYD2_k127_92719_2	1396141.BATP01000002_gene4809	6.752e-58	204.0	COG1943@1|root,COG1943@2|Bacteria,46W84@74201|Verrucomicrobia,2IVXZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SYD2_k127_92719_0	1122223.KB890700_gene1902	3.046e-137	450.0	28UBU@1|root,2ZGH7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_92719_3	204669.Acid345_1624	8.4e-26	114.0	COG4447@1|root,COG4447@2|Bacteria,3Y2SN@57723|Acidobacteria,2JIF7@204432|Acidobacteriia	204432|Acidobacteriia	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SYD2_k127_96429_0	1382359.JIAL01000001_gene12	3.064e-138	446.0	COG1964@1|root,COG1964@2|Bacteria,3Y2WC@57723|Acidobacteria,2JHTH@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
SYD2_k127_96429_4	682795.AciX8_4485	2.992e-16	79.0	COG0828@1|root,COG0828@2|Bacteria,3Y5J9@57723|Acidobacteria,2JJWG@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
SYD2_k127_96429_2	224324.aq_832	1.237e-68	243.0	COG0496@1|root,COG0496@2|Bacteria,2G3WU@200783|Aquificae	200783|Aquificae	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SYD2_k127_96429_3	1304885.AUEY01000022_gene3406	1.165e-61	220.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2MHNG@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SYD2_k127_96429_1	265072.Mfla_1749	2.917e-86	289.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VUZH@28216|Betaproteobacteria,2KKCA@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SYD2_k127_96669_6	1382359.JIAL01000001_gene702	1.164e-58	225.0	COG0308@1|root,COG0457@1|root,COG0308@2|Bacteria,COG0457@2|Bacteria,3Y3C5@57723|Acidobacteria,2JI5M@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1,TPR_11,TPR_16
SYD2_k127_96669_3	1122179.KB890458_gene744	7.219e-96	330.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1IPY5@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SYD2_k127_96669_4	926556.Echvi_1781	3.302e-83	297.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,47M2G@768503|Cytophagia	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SYD2_k127_96669_10	760142.Hipma_0764	8.102e-13	83.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,42R0Q@68525|delta/epsilon subdivisions,2WN87@28221|Deltaproteobacteria,2M6TA@213113|Desulfurellales	28221|Deltaproteobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SYD2_k127_96669_11	1340493.JNIF01000004_gene240	2.556e-12	79.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,Peptidase_M56,TonB_2,TonB_C
SYD2_k127_96669_5	370438.PTH_0066	1.092e-78	271.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,260K0@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SYD2_k127_96669_9	1144275.COCOR_01500	3.679e-18	86.0	2DNYP@1|root,32ZTI@2|Bacteria,1N747@1224|Proteobacteria,42XZ1@68525|delta/epsilon subdivisions,2WTGJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
SYD2_k127_96669_7	1230343.CANP01000024_gene1876	3.697e-28	127.0	COG0726@1|root,COG0726@2|Bacteria,1NHC2@1224|Proteobacteria,1SGBD@1236|Gammaproteobacteria,1JCCV@118969|Legionellales	118969|Legionellales	G	Protein of unknown function (DUF3298)	yjeA	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
SYD2_k127_96669_8	996637.SGM_1179	6.894e-27	117.0	COG2954@1|root,COG2954@2|Bacteria,2IHDK@201174|Actinobacteria	201174|Actinobacteria	L	triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_96669_2	1340493.JNIF01000003_gene3520	6.449e-108	364.0	COG1228@1|root,COG1228@2|Bacteria,3Y47R@57723|Acidobacteria	57723|Acidobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SYD2_k127_96669_1	1047013.AQSP01000079_gene2039	2.212e-145	472.0	2C57D@1|root,2Z7RS@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
SYD2_k127_96669_0	1192034.CAP_4888	2.707e-162	522.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,2YX5D@29|Myxococcales	28221|Deltaproteobacteria	E	Aconitase C-terminal domain	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SYD2_k127_97890_16	903818.KI912268_gene1151	5.075e-50	187.0	2E1QZ@1|root,32X13@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_97890_5	240015.ACP_3346	9.517e-149	501.0	COG5009@1|root,COG5009@2|Bacteria,3Y31C@57723|Acidobacteria,2JHJY@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SYD2_k127_97890_7	1042163.BRLA_c019660	3.645e-103	349.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,26WHW@186822|Paenibacillaceae	91061|Bacilli	E	DegT/DnrJ/EryC1/StrS aminotransferase family	aspB	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297	2.6.1.1,2.6.1.14	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052	RC00006,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SYD2_k127_97890_14	204669.Acid345_0567	1.631e-58	208.0	COG0669@1|root,COG0669@2|Bacteria,3Y4B6@57723|Acidobacteria,2JJ6A@204432|Acidobacteriia	204432|Acidobacteriia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SYD2_k127_97890_0	321327.CYA_2411	0.0	1411.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1G0PS@1117|Cyanobacteria,1GZKK@1129|Synechococcus	1117|Cyanobacteria	H	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SYD2_k127_97890_17	1278073.MYSTI_03333	2.347e-46	181.0	COG0204@1|root,COG0204@2|Bacteria,1PZS9@1224|Proteobacteria,434JR@68525|delta/epsilon subdivisions,2WYX1@28221|Deltaproteobacteria,2Z0U7@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SYD2_k127_97890_15	502025.Hoch_2148	6.468e-57	210.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,42W6W@68525|delta/epsilon subdivisions,2X6V3@28221|Deltaproteobacteria,2YUYD@29|Myxococcales	28221|Deltaproteobacteria	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SYD2_k127_97890_21	697282.Mettu_3684	2.065e-36	141.0	2E3V1@1|root,32YSA@2|Bacteria,1N7HB@1224|Proteobacteria,1SF7K@1236|Gammaproteobacteria,1XGMP@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_97890_20	497964.CfE428DRAFT_4951	7.685e-37	146.0	COG5485@1|root,COG5485@2|Bacteria,46T9K@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SYD2_k127_97890_18	1048983.EL17_23145	1.549e-42	160.0	COG1943@1|root,COG1943@2|Bacteria,4NPPG@976|Bacteroidetes,47RSC@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SYD2_k127_97890_9	404589.Anae109_1211	8.831e-90	307.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2YXN2@29|Myxococcales	28221|Deltaproteobacteria	GM	epimerase dehydratase	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD,Epimerase
SYD2_k127_97890_1	1242864.D187_010275	0.0	1288.0	COG0204@1|root,COG1022@1|root,COG3320@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,COG3320@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria,2YU6Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Male sterility protein	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
SYD2_k127_97890_25	1210884.HG799465_gene11652	1.349e-11	72.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4
SYD2_k127_97890_4	404589.Anae109_1213	5.08e-226	713.0	COG3875@1|root,COG3875@2|Bacteria,1RFFK@1224|Proteobacteria,43957@68525|delta/epsilon subdivisions,2X4BI@28221|Deltaproteobacteria,2YYP6@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SYD2_k127_97890_23	1168034.FH5T_02850	1.222e-26	113.0	2DNS7@1|root,32YWC@2|Bacteria,4NSJ6@976|Bacteroidetes,2G3HH@200643|Bacteroidia	976|Bacteroidetes	J	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SYD2_k127_97890_12	404589.Anae109_1214	1.62e-74	257.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,42TQ7@68525|delta/epsilon subdivisions,2WS2Q@28221|Deltaproteobacteria,2Z36A@29|Myxococcales	28221|Deltaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SYD2_k127_97890_22	644282.Deba_0069	5.943e-33	139.0	COG0457@1|root,COG0457@2|Bacteria,1NNP4@1224|Proteobacteria,42VPE@68525|delta/epsilon subdivisions,2WRZ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
SYD2_k127_97890_3	1267534.KB906754_gene3507	9.674e-267	852.0	COG1615@1|root,COG1615@2|Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SYD2_k127_97890_8	357808.RoseRS_1529	4.835e-100	345.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SYD2_k127_97890_6	234267.Acid_6499	6.02e-136	450.0	COG0006@1|root,COG0006@2|Bacteria,3Y36W@57723|Acidobacteria	57723|Acidobacteria	E	peptidase M24B X-Pro dipeptidase aminopeptidase domain protein	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SYD2_k127_97890_13	926561.KB900618_gene362	2.57e-61	221.0	COG2503@1|root,COG2503@2|Bacteria,1UYMJ@1239|Firmicutes,24E99@186801|Clostridia	186801|Clostridia	M	5'-nucleotidase, lipoprotein e(P4) family	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B,LysM
SYD2_k127_97890_26	42256.RradSPS_0911	2.74e-07	56.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SYD2_k127_97890_19	867845.KI911784_gene3218	2.827e-38	148.0	COG3170@1|root,COG3427@1|root,COG3170@2|Bacteria,COG3427@2|Bacteria,2G6U6@200795|Chloroflexi,376AP@32061|Chloroflexia	32061|Chloroflexia	NU	PFAM carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SYD2_k127_97890_10	479434.Sthe_1400	5.618e-83	286.0	COG1319@1|root,COG1319@2|Bacteria,2G60Y@200795|Chloroflexi,27XP9@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SYD2_k127_97890_2	234267.Acid_2226	1.413e-301	944.0	COG1529@1|root,COG1529@2|Bacteria,3Y6BF@57723|Acidobacteria	57723|Acidobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SYD2_k127_97890_11	926560.KE387023_gene2252	1.124e-75	256.0	COG2080@1|root,COG2080@2|Bacteria,1WK3N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SYD2_k127_97890_27	1476876.JOJO01000019_gene385	0.0002321	53.0	2BMEW@1|root,32FZF@2|Bacteria,2H0ZS@201174|Actinobacteria	201174|Actinobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
SYD2_k127_985370_0	1267535.KB906767_gene2200	8.842e-228	724.0	COG0473@1|root,COG0473@2|Bacteria,3Y3BC@57723|Acidobacteria,2JKC7@204432|Acidobacteriia	204432|Acidobacteriia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SYD2_k127_985370_1	234267.Acid_7718	9.601e-84	296.0	COG1193@1|root,COG1193@2|Bacteria,3Y2Z2@57723|Acidobacteria	57723|Acidobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SYD2_k127_998639_10	485913.Krac_12159	1.784e-06	56.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FHA,zinc_ribbon_2
SYD2_k127_998639_8	1123508.JH636440_gene2073	3.779e-14	76.0	COG2314@1|root,COG2314@2|Bacteria,2J1MD@203682|Planctomycetes	203682|Planctomycetes	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_998639_6	517418.Ctha_1405	8.943e-57	218.0	COG4591@1|root,COG4591@2|Bacteria,1FECJ@1090|Chlorobi	1090|Chlorobi	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SYD2_k127_998639_9	324602.Caur_0229	4.329e-08	63.0	COG3453@1|root,COG3453@2|Bacteria,2GB3Y@200795|Chloroflexi,3778V@32061|Chloroflexia	32061|Chloroflexia	S	Putative phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
SYD2_k127_998639_5	234267.Acid_0084	2.029e-61	225.0	2EZNS@1|root,33STS@2|Bacteria,3Y75C@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SYD2_k127_998639_0	234267.Acid_0085	3.855e-236	745.0	COG1132@1|root,COG1132@2|Bacteria,3Y6PT@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
SYD2_k127_998639_1	1303518.CCALI_00492	1.93e-206	663.0	COG0855@1|root,COG0855@2|Bacteria	2|Bacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SYD2_k127_998639_7	118168.MC7420_3851	1.072e-30	130.0	COG0637@1|root,COG0637@2|Bacteria,1G0E4@1117|Cyanobacteria,1H8DR@1150|Oscillatoriales	1117|Cyanobacteria	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	3.1.3.18,5.4.2.6	ko:K01091,ko:K01838	ko00500,ko00630,ko01100,ko01110,ko01130,map00500,map00630,map01100,map01110,map01130	-	R01334,R02728,R11310	RC00017,RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
SYD2_k127_998639_4	497964.CfE428DRAFT_2318	1.498e-61	223.0	COG0664@1|root,COG4420@1|root,COG0664@2|Bacteria,COG4420@2|Bacteria,46T5T@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003,cNMP_binding
SYD2_k127_998639_3	316274.Haur_2605	2.434e-64	228.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi,375II@32061|Chloroflexia	32061|Chloroflexia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SYD2_k127_998639_2	383372.Rcas_0031	1.505e-124	421.0	COG2114@1|root,COG2114@2|Bacteria,2GBUH@200795|Chloroflexi,376W9@32061|Chloroflexia	32061|Chloroflexia	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
## 3412 queries scanned
## Total time (seconds): 183.87908959388733
## Rate: 18.56 q/s