## Tue Nov 12 07:13:44 2024 ## emapper-2.1.12 ## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/4635/T/TGS3_bin.11.fa -m mmseqs --itype genome -o TGS3_bin.11 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/TGS3_bin.11 --cpu 28 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs TGS3_k127_100600_0 1081640.AGFU01000040_gene3269 8.748e-226 711.0 COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,2TRC4@28211|Alphaproteobacteria,2JZZG@204457|Sphingomonadales 204457|Sphingomonadales H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP TGS3_k127_100600_2 1247963.JPHU01000008_gene2818 4.534e-189 608.0 COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,2TVJ5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Peptidase, M28 - - - - - - - - - - - - PA,Peptidase_M28 TGS3_k127_100600_15 1090318.ATTI01000001_gene500 1.563e-06 53.0 2AM6V@1|root,31C1G@2|Bacteria,1P2MK@1224|Proteobacteria,2UV1F@28211|Alphaproteobacteria,2K704@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - TGS3_k127_100600_3 522306.CAP2UW1_0859 4.88e-150 485.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 TGS3_k127_100600_6 1123269.NX02_24200 1.189e-68 243.0 COG1216@1|root,COG1216@2|Bacteria,1R5GW@1224|Proteobacteria,2TTEN@28211|Alphaproteobacteria,2K3YZ@204457|Sphingomonadales 204457|Sphingomonadales S Glycosyltransferase like family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 TGS3_k127_100600_14 946483.Cenrod_1374 9.495e-07 61.0 COG0760@1|root,COG0760@2|Bacteria,1R4EF@1224|Proteobacteria,2VK6Z@28216|Betaproteobacteria,4AGDR@80864|Comamonadaceae 28216|Betaproteobacteria O PPIC-type PPIASE domain - - - - - - - - - - - - Rotamase_2,SurA_N_3 TGS3_k127_100600_13 391600.ABRU01000039_gene1909 2.734e-10 73.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,2TT1Y@28211|Alphaproteobacteria,2KFQ5@204458|Caulobacterales 204458|Caulobacterales D PFAM lipopolysaccharide biosynthesis protein - - - ko:K16554 ko05111,map05111 - - - ko00000,ko00001,ko02000 8.A.3.1 - - AAA_31,GNVR,Wzz TGS3_k127_100600_12 344747.PM8797T_21948 2.314e-19 100.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2IYTW@203682|Planctomycetes 203682|Planctomycetes D CobQ CobB MinD ParA nucleotide binding domain - - - ko:K16554 ko05111,map05111 - - - ko00000,ko00001,ko02000 8.A.3.1 - - AAA_31,CbiA,Wzz TGS3_k127_100600_8 1123392.AQWL01000009_gene1059 2.95e-50 192.0 COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2VHWW@28216|Betaproteobacteria 28216|Betaproteobacteria C eight transmembrane protein EpsH - - - - - - - - - - - - Exosortase_EpsH TGS3_k127_100600_11 1144342.PMI40_01462 4.333e-22 105.0 COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2VHWW@28216|Betaproteobacteria,4731H@75682|Oxalobacteraceae 28216|Betaproteobacteria C Transmembrane exosortase (Exosortase_EpsH) - - - - - - - - - - - - DUF3485,Exosortase_EpsH TGS3_k127_100600_9 240015.ACP_0045 1.118e-36 151.0 COG1216@1|root,COG1216@2|Bacteria,3Y59U@57723|Acidobacteria,2JJU8@204432|Acidobacteriia 204432|Acidobacteriia S PFAM Glycosyl transferase family 2 - - - ko:K07011 - - - - ko00000 - - - Glycos_transf_2 TGS3_k127_100600_4 1122613.ATUP01000002_gene2618 7.524e-136 446.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,43ZKS@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Mechanosensitive ion channel MA20_40450 - - - - - - - - - - - MS_channel TGS3_k127_100600_7 1247963.JPHU01000002_gene2721 7.408e-51 187.0 2CX65@1|root,32T1A@2|Bacteria,1MZ48@1224|Proteobacteria,2VGPF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_100600_10 935840.JAEQ01000002_gene3631 9.013e-24 108.0 28I3D@1|root,2Z876@2|Bacteria,1P0DR@1224|Proteobacteria,2TTG2@28211|Alphaproteobacteria,43IJ3@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S PilZ domain MA20_31715 - - - - - - - - - - - PilZ TGS3_k127_100600_1 414684.RC1_3493 8.618e-220 702.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2TTAX@28211|Alphaproteobacteria,2JYHC@204441|Rhodospirillales 204441|Rhodospirillales E Prolyl oligopeptidase, N-terminal beta-propeller domain - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N TGS3_k127_100600_5 314254.OA2633_09734 3.738e-133 439.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2TRET@28211|Alphaproteobacteria,43X36@69657|Hyphomonadaceae 28211|Alphaproteobacteria U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF TGS3_k127_1007768_0 1247963.JPHU01000002_gene2706 1.2e-322 1004.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2TQPK@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 TGS3_k127_1007768_2 190650.CC_0636 7.94e-76 262.0 2C6NZ@1|root,335K8@2|Bacteria,1N2AP@1224|Proteobacteria,2UQJB@28211|Alphaproteobacteria,2KI4B@204458|Caulobacterales 204458|Caulobacterales - - - - - - - - - - - - - - - TGS3_k127_1007768_3 314260.PB2503_04722 7.523e-44 166.0 2C2J5@1|root,315UG@2|Bacteria,1RHAH@1224|Proteobacteria,2U94W@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF3576) - - - - - - - - - - - - DUF3576 TGS3_k127_1007768_1 1247963.JPHU01000002_gene2708 4.235e-115 385.0 COG3203@1|root,COG3203@2|Bacteria 2|Bacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Porin_2,Porin_4 TGS3_k127_1007768_4 551275.KB899544_gene1303 2.438e-31 133.0 COG3324@1|root,COG3324@2|Bacteria,1N0AD@1224|Proteobacteria,2UD6F@28211|Alphaproteobacteria,43YEX@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Glyoxalase-like domain - - - ko:K06996 - - - - ko00000 - - - Glyoxalase TGS3_k127_1010322_0 1247963.JPHU01000011_gene742 3.214e-130 428.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2TRPB@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DUF3646 TGS3_k127_1010322_3 1247963.JPHU01000011_gene743 6.67e-34 133.0 COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2UBQB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection ybaB - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd TGS3_k127_1010322_4 1522072.IL54_3625 1.42e-14 78.0 29NRJ@1|root,309PI@2|Bacteria,1NQET@1224|Proteobacteria,2UK3F@28211|Alphaproteobacteria,2K88N@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - TGS3_k127_1010322_1 1247963.JPHU01000011_gene788 1.651e-84 286.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2TRZM@28211|Alphaproteobacteria 28211|Alphaproteobacteria L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 TGS3_k127_1010322_2 1161401.ASJA01000001_gene244 2.459e-50 185.0 COG4638@1|root,COG4638@2|Bacteria,1MV2G@1224|Proteobacteria,2TT1V@28211|Alphaproteobacteria,43WZM@69657|Hyphomonadaceae 28211|Alphaproteobacteria P COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - - - - - - - - - - Rieske TGS3_k127_1018092_1 1112214.AHIS01000089_gene904 7.52e-129 421.0 COG0654@1|root,COG0654@2|Bacteria,1NSGN@1224|Proteobacteria,2UPGQ@28211|Alphaproteobacteria,2KEGZ@204457|Sphingomonadales 204457|Sphingomonadales CH Tryptophan halogenase - - - - - - - - - - - - Trp_halogenase TGS3_k127_1018092_2 1122612.AUBA01000002_gene1836 2.841e-51 190.0 COG0665@1|root,COG0665@2|Bacteria,1RH7N@1224|Proteobacteria,2U9PJ@28211|Alphaproteobacteria,2K4FY@204457|Sphingomonadales 204457|Sphingomonadales E tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - - - - - - - - - - - TGS3_k127_1018092_0 1234364.AMSF01000033_gene408 4.193e-216 681.0 COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,1RMJY@1236|Gammaproteobacteria,1X9JZ@135614|Xanthomonadales 135614|Xanthomonadales E Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase TGS3_k127_1018092_3 1242864.D187_002951 1.554e-34 155.0 COG2355@1|root,COG2355@2|Bacteria,1MXA0@1224|Proteobacteria,43F3Q@68525|delta/epsilon subdivisions,2X3A4@28221|Deltaproteobacteria,2YV2U@29|Myxococcales 28221|Deltaproteobacteria E Membrane dipeptidase (Peptidase family M19) - - - - - - - - - - - - Peptidase_M19 TGS3_k127_1045135_0 69395.JQLZ01000002_gene1279 2.871e-70 247.0 COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2U0BA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III - - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 TGS3_k127_1045135_1 521719.ATXQ01000003_gene2047 0.000885 46.0 COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,1YGEB@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Protein of unknown function (DUF423) ygdD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF423 TGS3_k127_104827_2 1294273.roselon_02367 6.197e-53 186.0 COG3460@1|root,COG3460@2|Bacteria,1RHM5@1224|Proteobacteria,2U9HF@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q phenylacetic acid degradation paaB - - ko:K02610 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - PaaB TGS3_k127_104827_0 1117943.SFHH103_02470 1.986e-187 589.0 COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,2TTC4@28211|Alphaproteobacteria,4B8JA@82115|Rhizobiaceae 28211|Alphaproteobacteria S phenylacetic acid degradation protein paaA - 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC TGS3_k127_104827_3 1122214.AQWH01000003_gene4008 3.149e-32 146.0 COG0708@1|root,COG4625@1|root,COG0708@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,2TSB7@28211|Alphaproteobacteria,2PJFJ@255475|Aurantimonadaceae 28211|Alphaproteobacteria I protein with a C-terminal OMP (outer membrane protein) domain - - - - - - - - - - - - Autotransporter,Exo_endo_phos,PATR TGS3_k127_104827_1 1090320.KB900605_gene3041 6.317e-82 275.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2K04I@204457|Sphingomonadales 204457|Sphingomonadales I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N TGS3_k127_104956_1 748247.AZKH_1952 7.679e-64 230.0 COG0596@1|root,COG0596@2|Bacteria,1N5ZI@1224|Proteobacteria,2VJ9I@28216|Betaproteobacteria 28216|Betaproteobacteria S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 TGS3_k127_104956_0 1280949.HAD_14997 3.713e-182 578.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQU2@28211|Alphaproteobacteria,43XCZ@69657|Hyphomonadaceae 28211|Alphaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - - ko:K09456 - - - - ko00000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M TGS3_k127_105060_1 1197906.CAJQ02000052_gene4496 1.781e-82 292.0 COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,2TSUT@28211|Alphaproteobacteria,3JS53@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Prephenate dehydratase pheA - 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 - - - PDT TGS3_k127_105060_4 1247963.JPHU01000011_gene733 5.481e-48 181.0 COG3474@1|root,COG3474@2|Bacteria,1RIDN@1224|Proteobacteria,2U142@28211|Alphaproteobacteria 28211|Alphaproteobacteria C cytochrome cycM - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C TGS3_k127_105060_3 177439.DP2816 1.269e-51 194.0 COG2930@1|root,COG2930@2|Bacteria,1RHV6@1224|Proteobacteria,42TN0@68525|delta/epsilon subdivisions,2WQ75@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Las17-binding protein actin regulator - - - - - - - - - - - - Ysc84 TGS3_k127_105060_0 439496.RBY4I_3066 1.191e-111 370.0 COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,2TSJP@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Radical SAM domain protein - - - - - - - - - - - - Fer4_12,Fer4_14,Radical_SAM TGS3_k127_105060_2 1121033.AUCF01000003_gene3348 3.282e-62 222.0 COG2813@1|root,COG2813@2|Bacteria,1RHAE@1224|Proteobacteria,2U5V5@28211|Alphaproteobacteria,2JYYC@204441|Rhodospirillales 204441|Rhodospirillales J Protein of unknown function (DUF938) - - - - - - - - - - - - DUF938 TGS3_k127_1060869_5 717785.HYPMC_0035 9.65e-26 109.0 COG0640@1|root,COG0640@2|Bacteria,1N2P4@1224|Proteobacteria,2UFNP@28211|Alphaproteobacteria,3N7E0@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 TGS3_k127_1060869_4 573065.Astex_1185 8.566e-40 149.0 COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,2UCR7@28211|Alphaproteobacteria,2KH2C@204458|Caulobacterales 204458|Caulobacterales S Belongs to the UPF0145 family - - - - - - - - - - - - YbjQ_1 TGS3_k127_1060869_8 1282362.AEAC466_02715 0.0002282 50.0 2BZRI@1|root,2ZHKH@2|Bacteria,1P717@1224|Proteobacteria,2UYFR@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_1060869_6 391626.OAN307_c29530 1.808e-05 52.0 COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria 1224|Proteobacteria N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliN - - ko:K02417,ko:K03225 ko02030,ko02040,ko03070,map02030,map02040,map03070 M00332,M00542,M00660 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.6.1,3.A.6.2,3.A.6.3 - - FliMN_C TGS3_k127_1060869_0 316056.RPC_3348 9.475e-95 316.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2TRXJ@28211|Alphaproteobacteria,3JTKG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB TGS3_k127_1060869_1 715226.ABI_20820 3.023e-80 280.0 COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2TTTU@28211|Alphaproteobacteria,2KIP9@204458|Caulobacterales 204458|Caulobacterales GM epimerase - - - - - - - - - - - - Epimerase TGS3_k127_1060869_3 252305.OB2597_07760 4.454e-43 166.0 COG5387@1|root,COG5387@2|Bacteria,1Q3B5@1224|Proteobacteria,2TVK1@28211|Alphaproteobacteria,2PDH7@252301|Oceanicola 28211|Alphaproteobacteria O ATP12 chaperone protein - - - - - - - - - - - - ATP12 TGS3_k127_1060869_2 1247963.JPHU01000008_gene2806 8.368e-70 244.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2TTQC@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluC GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 TGS3_k127_1061427_2 1235457.C404_03965 7.905e-33 129.0 COG3657@1|root,COG3657@2|Bacteria,1N74C@1224|Proteobacteria,2VVRD@28216|Betaproteobacteria,1KHD9@119060|Burkholderiaceae 28216|Betaproteobacteria S Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 TGS3_k127_1061427_1 1123228.AUIH01000097_gene1761 1.669e-34 134.0 COG3636@1|root,COG3636@2|Bacteria,1N75D@1224|Proteobacteria,1SC8G@1236|Gammaproteobacteria,1XQX5@135619|Oceanospirillales 135619|Oceanospirillales K addiction module antidote protein - - - - - - - - - - - - HTH_3 TGS3_k127_1061427_3 1382303.JPOM01000001_gene1253 7.534e-15 83.0 COG1073@1|root,COG1073@2|Bacteria,1RJ7T@1224|Proteobacteria 1224|Proteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 TGS3_k127_1061427_4 1114964.L485_11305 3.819e-08 63.0 COG4544@1|root,COG4544@2|Bacteria,1MY56@1224|Proteobacteria,2U9Y7@28211|Alphaproteobacteria,2K4KW@204457|Sphingomonadales 204457|Sphingomonadales S SOS response - - - ko:K14160 - - - - ko00000,ko03400 - - - - TGS3_k127_1061427_0 935261.JAGL01000004_gene893 7.4e-91 319.0 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2TQVR@28211|Alphaproteobacteria,43H48@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L Nucleotidyltransferase DNA polymerase involved in DNA repair imuB - - ko:K14161 - - - - ko00000,ko03400 - - - IMS TGS3_k127_1080615_5 1123240.ATVO01000003_gene232 1.876e-32 134.0 COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2TUER@28211|Alphaproteobacteria,2K4AD@204457|Sphingomonadales 204457|Sphingomonadales M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR TGS3_k127_1080615_0 1207063.P24_15339 5.237e-111 371.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TS1P@28211|Alphaproteobacteria,2JQF3@204441|Rhodospirillales 204441|Rhodospirillales M Belongs to the peptidase S11 family dacA - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 TGS3_k127_1080615_3 509190.Cseg_2123 7.908e-61 218.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2U72D@28211|Alphaproteobacteria,2KGC2@204458|Caulobacterales 204458|Caulobacterales F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk - 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin TGS3_k127_1080615_4 633149.Bresu_1993 1.996e-48 187.0 COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2TV3E@28211|Alphaproteobacteria,2KF0N@204458|Caulobacterales 204458|Caulobacterales L DNA polymerase III - - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2 TGS3_k127_1080615_2 1247963.JPHU01000009_gene2298 2.919e-95 319.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2TS88@28211|Alphaproteobacteria 28211|Alphaproteobacteria L hydrolase, TatD family' tatD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase TGS3_k127_1080615_1 1161401.ASJA01000007_gene2132 9.072e-102 338.0 COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,2TQQN@28211|Alphaproteobacteria,43WX7@69657|Hyphomonadaceae 28211|Alphaproteobacteria S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I phnP - 3.1.4.55 ko:K06167 ko00440,map00440 - R10205 RC00296 ko00000,ko00001,ko01000 - - - Lactamase_B_2 TGS3_k127_1095297_1 228405.HNE_0649 6.961e-95 319.0 COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2TQJ9@28211|Alphaproteobacteria,43XAI@69657|Hyphomonadaceae 28211|Alphaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases ycbL GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 - - - - - - - - - - Lactamase_B TGS3_k127_1095297_2 1247963.JPHU01000002_gene2578 2.088e-58 212.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2TUWE@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C TGS3_k127_1095297_4 1267005.KB911256_gene1620 2.345e-17 85.0 COG5302@1|root,COG5302@2|Bacteria 2|Bacteria S Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid ccdA - - ko:K19164 - - - - ko00000,ko02048 - - - CcdA TGS3_k127_1095297_0 1247963.JPHU01000003_gene1194 1.002e-137 443.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2TR3W@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Belongs to the CarA family carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase TGS3_k127_1095721_1 1207058.L53_12765 9.742e-78 271.0 COG3391@1|root,COG3391@2|Bacteria,1RGAJ@1224|Proteobacteria,2U5SB@28211|Alphaproteobacteria,43YH2@69657|Hyphomonadaceae 28211|Alphaproteobacteria S amine dehydrogenase activity - - - - - - - - - - - - SGL TGS3_k127_1095721_0 314260.PB2503_03302 8.903e-125 409.0 COG0616@1|root,COG0616@2|Bacteria,1MY1I@1224|Proteobacteria,2U07G@28211|Alphaproteobacteria 28211|Alphaproteobacteria OU Serine dehydrogenase proteinase - - - - - - - - - - - - SDH_sah TGS3_k127_1099550_2 1038859.AXAU01000019_gene4797 4.41e-80 276.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2TRP4@28211|Alphaproteobacteria,3JR4X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 TGS3_k127_1099550_1 1247963.JPHU01000003_gene1230 1.936e-80 282.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2TRTP@28211|Alphaproteobacteria 28211|Alphaproteobacteria O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N TGS3_k127_1099550_0 272568.GDI0881 2.332e-90 309.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,2JP8N@204441|Rhodospirillales 204441|Rhodospirillales D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA TGS3_k127_1104845_15 258594.RPA1533 5.088e-45 168.0 COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,2U8I1@28211|Alphaproteobacteria,3K67X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T TspO/MBR family tspO - - ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 - - - ko00000,ko00001,ko02000 9.A.24 - - TspO_MBR TGS3_k127_1104845_4 1120956.JHZK01000006_gene669 3.144e-178 569.0 COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,2TVK0@28211|Alphaproteobacteria 28211|Alphaproteobacteria C geranylgeranyl reductase bchP - 1.3.1.111,1.3.1.83 ko:K10960 ko00860,ko00900,ko01100,ko01110,map00860,map00900,map01100,map01110 - R02063,R08754,R08755,R08756,R11226,R11518 RC00212,RC00522,RC01823 ko00000,ko00001,ko01000 - - - FAD_binding_3,Lycopene_cycl,NAD_binding_8,Pyr_redox_2 TGS3_k127_1104845_7 1547437.LL06_03085 4.272e-135 444.0 COG2211@1|root,COG2211@2|Bacteria,1MWE4@1224|Proteobacteria,2TQY7@28211|Alphaproteobacteria,43NC1@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G PUCC protein pucC2 - - ko:K08226 - - - - ko00000,ko02000 2.A.1.41 - - PUCC TGS3_k127_1104845_9 1101192.KB910516_gene720 6.006e-124 407.0 COG0382@1|root,COG0382@2|Bacteria,1MVS1@1224|Proteobacteria,2TVKN@28211|Alphaproteobacteria,1JTGW@119045|Methylobacteriaceae 28211|Alphaproteobacteria H TIGRFAM bacteriochlorophyll chlorophyll synthetase bchG - 2.5.1.133,2.5.1.62 ko:K04040 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R06284,R09067,R11514,R11517 RC00020 ko00000,ko00001,ko01000,ko01006 - - - UbiA TGS3_k127_1104845_8 414684.RC1_2118 2.183e-126 419.0 COG2204@1|root,COG2204@2|Bacteria,1P98K@1224|Proteobacteria,2TUM0@28211|Alphaproteobacteria,2JR4F@204441|Rhodospirillales 204441|Rhodospirillales T Bacterial regulatory protein, Fis family - - - - - - - - - - - - HTH_8,PAS,PAS_4,PAS_8,PAS_9 TGS3_k127_1104845_13 519989.ECTPHS_08176 6.871e-53 199.0 COG5012@1|root,COG5012@2|Bacteria,1RJN6@1224|Proteobacteria 1224|Proteobacteria S B12-binding aerR - - - - - - - - - - - B12-binding,B12-binding_2 TGS3_k127_1104845_12 414684.RC1_2116 1.772e-61 216.0 294R4@1|root,2ZS4D@2|Bacteria,1RDGM@1224|Proteobacteria,2U71V@28211|Alphaproteobacteria,2JS6B@204441|Rhodospirillales 204441|Rhodospirillales S 2-vinyl bacteriochlorophyllide hydratase (BCHF) bchF - 4.2.1.165 ko:K11336 ko00860,ko01110,map00860,map01110 - R09054,R09059 RC02412 ko00000,ko00001,ko01000 - - - BCHF TGS3_k127_1104845_2 426117.M446_3718 4.342e-203 639.0 COG2710@1|root,COG2710@2|Bacteria,1MVP0@1224|Proteobacteria,2TSK1@28211|Alphaproteobacteria,1JSC9@119045|Methylobacteriaceae 28211|Alphaproteobacteria H Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex bchN - 1.3.7.7 ko:K04038 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R06282 RC01008 ko00000,ko00001,ko01000 - - - Oxidored_nitro TGS3_k127_1104845_1 519989.ECTPHS_08161 1.789e-226 715.0 COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,1RQR5@1236|Gammaproteobacteria,1WXMP@135613|Chromatiales 135613|Chromatiales F Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex bchB - 1.3.7.7 ko:K04039 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R06282 RC01008 ko00000,ko00001,ko01000 - - - Oxidored_nitro,PCP_red TGS3_k127_1104845_0 1000565.METUNv1_03973 0.0 1598.0 COG1429@1|root,COG1429@2|Bacteria,1MU5W@1224|Proteobacteria,2VI5I@28216|Betaproteobacteria,2KUI5@206389|Rhodocyclales 206389|Rhodocyclales H COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases - - - - - - - - - - - - CobN-Mg_chel TGS3_k127_1104845_6 1120956.JHZK01000006_gene658 2.67e-152 486.0 COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,2TSKC@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP bchL - 1.3.7.7 ko:K04037 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R06282 RC01008 ko00000,ko00001,ko01000 - - - Fer4_NifH TGS3_k127_1104845_10 1121861.KB899935_gene418 1.096e-89 301.0 COG2227@1|root,COG2227@2|Bacteria,1N2VZ@1224|Proteobacteria,2TU4Z@28211|Alphaproteobacteria,2JR97@204441|Rhodospirillales 204441|Rhodospirillales H Magnesium-protoporphyrin IX methyltransferase C-terminus bchM - 2.1.1.11 ko:K03428 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R04237 RC00003,RC00460 ko00000,ko00001,ko01000 - - - MTS,Mg-por_mtran_C,PrmA TGS3_k127_1104845_3 1120956.JHZK01000006_gene656 9.109e-182 584.0 COG0477@1|root,COG2814@2|Bacteria,1MW95@1224|Proteobacteria,2TS8H@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Major facilitator superfamily lhaA - - ko:K08226 - - - - ko00000,ko02000 2.A.1.41 - - PUCC TGS3_k127_1104845_11 633149.Bresu_3070 2.089e-81 279.0 COG3861@1|root,COG3861@2|Bacteria,1NU42@1224|Proteobacteria,2TTV5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S photosynthetic reaction center H subunit puhA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009579,GO:0016020,GO:0034357,GO:0042716,GO:0042717,GO:0044424,GO:0044436,GO:0044444,GO:0044464 - ko:K13991 ko02020,map02020 - - - ko00000,ko00001,ko00194 - - - PRC,PRCH TGS3_k127_1104845_14 1382303.JPOM01000001_gene1644 2.801e-45 174.0 COG3428@1|root,COG3428@2|Bacteria,1RHA4@1224|Proteobacteria,2UA6D@28211|Alphaproteobacteria,2KISC@204458|Caulobacterales 204458|Caulobacterales S Bacterial PH domain - - - - - - - - - - - - bPH_2 TGS3_k127_1104845_17 269796.Rru_A0615 1.136e-14 79.0 2E3IS@1|root,32YH7@2|Bacteria,1N9I5@1224|Proteobacteria,2UGHF@28211|Alphaproteobacteria,2JUBF@204441|Rhodospirillales 204441|Rhodospirillales S Photosynthetic complex assembly protein - - - - - - - - - - - - - TGS3_k127_1104845_16 1123240.ATVO01000008_gene2359 1.158e-23 102.0 2E7QH@1|root,3325Y@2|Bacteria,1MZ3C@1224|Proteobacteria,2UG5F@28211|Alphaproteobacteria,2K7KS@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - TGS3_k127_1104845_5 1379701.JPJC01000083_gene2161 3.678e-159 508.0 COG1633@1|root,COG1633@2|Bacteria,1N5FH@1224|Proteobacteria,2TU0E@28211|Alphaproteobacteria,2K1MB@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) acsF - 1.14.13.81 ko:K04035 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R06265,R06266,R06267,R10068 RC00741,RC01491,RC01492,RC03042 ko00000,ko00001,ko01000 - - - Rubrerythrin TGS3_k127_1109204_7 1121456.ATVA01000017_gene133 0.0007259 45.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2WJ2S@28221|Deltaproteobacteria,2M8VE@213115|Desulfovibrionales 28221|Deltaproteobacteria NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg TGS3_k127_1109204_0 1244869.H261_09227 2.542e-153 499.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2TQU9@28211|Alphaproteobacteria,2JPEV@204441|Rhodospirillales 204441|Rhodospirillales E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N TGS3_k127_1109204_2 114615.BRADO3708 2.08e-91 309.0 COG0583@1|root,COG0583@2|Bacteria,1MVJ7@1224|Proteobacteria,2TT9Z@28211|Alphaproteobacteria,3K6DM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate TGS3_k127_1109204_5 113395.AXAI01000030_gene2672 7.601e-74 253.0 COG2128@1|root,COG2128@2|Bacteria,1RBG0@1224|Proteobacteria,2U4DJ@28211|Alphaproteobacteria,3K66U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD TGS3_k127_1109204_1 114615.BRADO3707 2.671e-109 361.0 COG1024@1|root,COG1024@2|Bacteria,1Q51H@1224|Proteobacteria,2U84X@28211|Alphaproteobacteria,3JZ8H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Enoyl-CoA hydratase/isomerase - - 3.7.1.18 ko:K20765 - - - - ko00000,ko01000 - - - ECH_1 TGS3_k127_1109204_6 452662.SJA_C1-19840 4.338e-56 204.0 COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,2VFDT@28211|Alphaproteobacteria,2KCB2@204457|Sphingomonadales 204457|Sphingomonadales O Redoxin - - - - - - - - - - - - AhpC-TSA TGS3_k127_1109204_3 1245469.S58_44340 2.318e-90 306.0 COG1028@1|root,COG1028@2|Bacteria,1R3ZC@1224|Proteobacteria,2U6BQ@28211|Alphaproteobacteria,3K5YQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 TGS3_k127_1109204_4 1247963.JPHU01000001_gene1763 1.423e-78 276.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2TQUB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Permease, YjgP YjgQ family MA20_28210 - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ TGS3_k127_111316_4 744979.R2A130_0650 5.725e-05 48.0 COG0593@1|root,COG0593@2|Bacteria,1N4PG@1224|Proteobacteria,2U96K@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the DnaA family hda - - - - - - - - - - - Bac_DnaA TGS3_k127_111316_1 314260.PB2503_08799 3.121e-85 305.0 COG3249@1|root,COG3249@2|Bacteria,1RE2R@1224|Proteobacteria,2U7HJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2066) - - - - - - - - - - - - DUF2066 TGS3_k127_111316_0 1247963.JPHU01000005_gene285 7.906e-138 448.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2TR6G@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C TGS3_k127_111316_2 1122135.KB893169_gene2415 5.691e-69 241.0 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2TRY6@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N,YjbR TGS3_k127_111316_3 1205680.CAKO01000040_gene651 1.287e-18 89.0 COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,2U0NZ@28211|Alphaproteobacteria,2JXIH@204441|Rhodospirillales 204441|Rhodospirillales S Protein of unknown function (DUF1499) - - - - - - - - - - - - DUF1499 TGS3_k127_11156_3 314260.PB2503_04097 3.466e-51 189.0 COG1846@1|root,COG1846@2|Bacteria,1RJRY@1224|Proteobacteria,2UA4D@28211|Alphaproteobacteria 28211|Alphaproteobacteria K COG1846 Transcriptional regulators - - - - - - - - - - - - MarR,MarR_2 TGS3_k127_11156_2 1121106.JQKB01000004_gene2380 2.624e-65 231.0 COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2U72I@28211|Alphaproteobacteria,2JSGG@204441|Rhodospirillales 204441|Rhodospirillales F Nudix N-terminal - - - - - - - - - - - - NUDIX,Nudix_N_2 TGS3_k127_11156_1 1247963.JPHU01000002_gene2546 3.952e-70 244.0 COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2U74X@28211|Alphaproteobacteria 28211|Alphaproteobacteria D probably involved in intracellular septation ispZ - - ko:K06190 - - - - ko00000 - - - IspA TGS3_k127_11156_0 1122962.AULH01000004_gene2452 3.324e-113 373.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2TS0M@28211|Alphaproteobacteria,36XI5@31993|Methylocystaceae 28211|Alphaproteobacteria U SRP54-type protein, GTPase domain ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N TGS3_k127_1123238_2 883078.HMPREF9695_02071 2.079e-65 231.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2TT58@28211|Alphaproteobacteria,3JU34@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - - - - - - - - - - - Carb_kinase,YjeF_N TGS3_k127_1123238_1 690850.Desaf_2604 9.286e-71 258.0 COG0671@1|root,COG0671@2|Bacteria,1MWK1@1224|Proteobacteria,431Z2@68525|delta/epsilon subdivisions,2WWQX@28221|Deltaproteobacteria 28221|Deltaproteobacteria I PAP2 superfamily - - - - - - - - - - - - PAP2 TGS3_k127_1123238_3 1156844.KB891801_gene2894 2.993e-43 166.0 COG1247@1|root,COG1247@2|Bacteria,2IHSY@201174|Actinobacteria 201174|Actinobacteria M acetyltransferase bar - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_4 TGS3_k127_1123238_4 1120963.KB894491_gene1107 4.383e-05 52.0 2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_1123238_0 1247963.JPHU01000004_gene571 1.176e-150 488.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2TS8W@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N TGS3_k127_1125604_4 1207058.L53_10210 1.254e-41 160.0 COG1309@1|root,COG1309@2|Bacteria,1N1R7@1224|Proteobacteria,2UBVA@28211|Alphaproteobacteria,43Y9D@69657|Hyphomonadaceae 28211|Alphaproteobacteria K COG1309 Transcriptional regulator - - - - - - - - - - - - TetR_N TGS3_k127_1125604_2 228405.HNE_2608 1.652e-81 285.0 COG0204@1|root,COG0204@2|Bacteria,1R5IR@1224|Proteobacteria,2TV3T@28211|Alphaproteobacteria,43XRS@69657|Hyphomonadaceae 28211|Alphaproteobacteria I Acyltransferase - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase TGS3_k127_1125604_3 314254.OA2633_03406 1.349e-52 202.0 COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,2TTGI@28211|Alphaproteobacteria,43XHQ@69657|Hyphomonadaceae 28211|Alphaproteobacteria I Transmembrane secretion effector aas - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - AMP-binding,Acyltransferase,MFS_1 TGS3_k127_1125604_0 1247963.JPHU01000002_gene2463 5.621e-122 399.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2TSIP@28211|Alphaproteobacteria 28211|Alphaproteobacteria M NAD-dependent epimerase dehydratase lspL - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd TGS3_k127_1125604_1 391625.PPSIR1_32622 9.794e-91 306.0 COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,4307A@68525|delta/epsilon subdivisions,2WV7X@28221|Deltaproteobacteria,2YVIM@29|Myxococcales 28221|Deltaproteobacteria G Inositol monophosphatase family - - - - - - - - - - - - Inositol_P TGS3_k127_1125604_5 314260.PB2503_08959 3.078e-38 149.0 COG1396@1|root,COG1396@2|Bacteria,1RDBW@1224|Proteobacteria,2U7CY@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator phrR - - - - - - - - - - - HTH_3 TGS3_k127_1127132_3 266834.SMc04345 0.0007284 46.0 2973J@1|root,2ZUBQ@2|Bacteria,1P4RU@1224|Proteobacteria,2UWBJ@28211|Alphaproteobacteria,4BFT7@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_1127132_2 1280954.HPO_14946 2.465e-38 146.0 2B5YT@1|root,31YUV@2|Bacteria,1RF42@1224|Proteobacteria,2U8FC@28211|Alphaproteobacteria,43YNV@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF3088) - - - - - - - - - - - - DUF3088 TGS3_k127_1127132_1 1280947.HY30_07025 2.267e-60 216.0 COG0457@1|root,COG0457@2|Bacteria,1QWT6@1224|Proteobacteria,2TXSR@28211|Alphaproteobacteria,43XSC@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - TGS3_k127_1127923_4 1247963.JPHU01000009_gene2347 1.19e-105 349.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2TR06@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Inositol monophosphatase suhB - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P TGS3_k127_1127923_3 314260.PB2503_10754 6.856e-119 401.0 COG2244@1|root,COG2244@2|Bacteria,1MUMD@1224|Proteobacteria,2TTZ8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Membrane protein involved in the export of O-antigen and teichoic acid - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt_3,Polysacc_synt_C TGS3_k127_1127923_1 1161401.ASJA01000009_gene1837 1.872e-163 533.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,43X1D@69657|Hyphomonadaceae 28211|Alphaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - - - - - - - - - - AMP-binding,AMP-binding_C TGS3_k127_1127923_0 1121948.AUAC01000002_gene1165 5.255e-184 582.0 COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TUVB@28211|Alphaproteobacteria,43WWF@69657|Hyphomonadaceae 28211|Alphaproteobacteria I acyl-CoA dehydrogenase MA20_22780 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N TGS3_k127_1127923_2 1247963.JPHU01000004_gene471 5.134e-154 494.0 COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,2TVBB@28211|Alphaproteobacteria 28211|Alphaproteobacteria I acyl-CoA dehydrogenase MA20_22775 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N TGS3_k127_1127923_5 394221.Mmar10_1649 3.713e-43 168.0 COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,2U9GG@28211|Alphaproteobacteria,43Y20@69657|Hyphomonadaceae 28211|Alphaproteobacteria I MaoC like domain nodN - - - - - - - - - - - MaoC_dehydratas TGS3_k127_11346_3 1207058.L53_02210 9.186e-138 450.0 COG2223@1|root,COG2223@2|Bacteria,1QY5G@1224|Proteobacteria,2TXGI@28211|Alphaproteobacteria,43XMD@69657|Hyphomonadaceae 28211|Alphaproteobacteria P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 TGS3_k127_11346_8 685778.AORL01000001_gene137 4.622e-41 169.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,2K04M@204457|Sphingomonadales 204457|Sphingomonadales S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_19,TPR_8 TGS3_k127_11346_2 291985.CCSI01000002_gene1632 2.89e-196 621.0 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,2TR3D@28211|Alphaproteobacteria,2K0NS@204457|Sphingomonadales 204457|Sphingomonadales E PFAM Serine dehydratase alpha chain sdaA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta TGS3_k127_11346_9 1121015.N789_13070 6.522e-40 161.0 COG1858@1|root,COG1858@2|Bacteria,1R7H4@1224|Proteobacteria 1224|Proteobacteria P Di-haem cytochrome c peroxidase - - - - - - - - - - - - CCP_MauG TGS3_k127_11346_5 1121015.N789_13065 5.168e-54 202.0 COG0457@1|root,COG0457@2|Bacteria 1121015.N789_13065|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - TGS3_k127_11346_4 1238182.C882_1254 2.651e-65 231.0 COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2TU5C@28211|Alphaproteobacteria,2JPM6@204441|Rhodospirillales 204441|Rhodospirillales S nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - - - - - - - - - - MoCF_biosynth TGS3_k127_11346_1 394221.Mmar10_0602 1.814e-256 805.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2TUZZ@28211|Alphaproteobacteria,43WPD@69657|Hyphomonadaceae 28211|Alphaproteobacteria EU X-Pro dipeptidyl-peptidase (S15 family) - - - - - - - - - - - - DPPIV_N,PD40,Peptidase_S9,Peptidase_S9_N TGS3_k127_11346_6 686578.AFFX01000011_gene2510 4.146e-49 178.0 COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL TGS3_k127_11346_7 1247963.JPHU01000002_gene2533 7.096e-48 177.0 COG5342@1|root,COG5342@2|Bacteria,1R46Z@1224|Proteobacteria,2U5KW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S invasion associated locus B - - - - - - - - - - - - - TGS3_k127_11346_0 1247963.JPHU01000002_gene2529 0.0 1121.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C TGS3_k127_1145979_2 1234595.C725_0025 2.828e-59 216.0 COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,2U7PM@28211|Alphaproteobacteria 28211|Alphaproteobacteria O COG0526 Thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA,Redoxin TGS3_k127_1145979_0 1247963.JPHU01000016_gene1051 8.03e-163 535.0 COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,2TTUM@28211|Alphaproteobacteria 28211|Alphaproteobacteria CO to be involved in C-type cytochrome biogenesis dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 TGS3_k127_1145979_1 1247963.JPHU01000001_gene1930 1.483e-76 264.0 COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,2U2IQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM SapC family protein - - - - - - - - - - - - SapC TGS3_k127_1158697_1 314285.KT71_12745 4.778e-174 556.0 COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,1RR4S@1236|Gammaproteobacteria,1J90K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sodium:solute symporter family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF TGS3_k127_1158697_0 935261.JAGL01000004_gene1001 2.504e-206 647.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQXI@28211|Alphaproteobacteria,43I0B@69277|Phyllobacteriaceae 28211|Alphaproteobacteria H Aminotransferase class I and II hemA - 2.3.1.37 ko:K00643 ko00260,ko00860,ko01100,ko01110,map00260,map00860,map01100,map01110 - R00830 RC00004,RC02815 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 TGS3_k127_1158697_2 1248917.ANFX01000016_gene2480 1.041e-27 119.0 COG0523@1|root,COG0523@2|Bacteria,1MY4T@1224|Proteobacteria,2U0DU@28211|Alphaproteobacteria,2K41B@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF3623) - - - - - - - - - - - - DUF3623 TGS3_k127_1196127_0 1479238.JQMZ01000001_gene2306 3.217e-84 291.0 COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,2TT93@28211|Alphaproteobacteria,43WBP@69657|Hyphomonadaceae 28211|Alphaproteobacteria N Plays a role in the flagellum-specific transport system fliP - - ko:K02419 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliP TGS3_k127_1196127_2 1161401.ASJA01000004_gene2332 5.418e-07 56.0 COG3190@1|root,COG3190@2|Bacteria,1MZV2@1224|Proteobacteria,2V9BA@28211|Alphaproteobacteria,440E7@69657|Hyphomonadaceae 28211|Alphaproteobacteria N flagellar - - - ko:K02418 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliO TGS3_k127_1196127_1 269796.Rru_A3091 2.255e-44 173.0 COG0438@1|root,COG0726@1|root,COG0438@2|Bacteria,COG0726@2|Bacteria,1MU9C@1224|Proteobacteria,2U0YF@28211|Alphaproteobacteria,2JS7Z@204441|Rhodospirillales 204441|Rhodospirillales M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 TGS3_k127_1204497_2 318167.Sfri_0040 3.595e-65 224.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,2QA8F@267890|Shewanellaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 TGS3_k127_1204497_1 1247963.JPHU01000012_gene910 3.663e-92 322.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2TR46@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_4,PAS_8 TGS3_k127_1204497_3 1121124.JNIX01000008_gene2213 2.327e-46 178.0 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2TQMN@28211|Alphaproteobacteria,2KFG1@204458|Caulobacterales 204458|Caulobacterales P Plays a role in the regulation of phosphate uptake phoU GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - ko:K02039 - - - - ko00000 - - - PhoU TGS3_k127_1204497_0 633149.Bresu_1703 2.737e-105 349.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,2KFH3@204458|Caulobacterales 204458|Caulobacterales K phosphate regulon transcriptional regulatory protein PhoB phoB - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C TGS3_k127_1206119_0 1121948.AUAC01000002_gene1570 0.0 1198.0 COG3485@1|root,COG3485@2|Bacteria,1QUNE@1224|Proteobacteria,2U26Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Domain of unknown function DUF11 - - - - - - - - - - - - DUF11 TGS3_k127_1221908_4 1500306.JQLA01000010_gene971 7.137e-05 51.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2TRK1@28211|Alphaproteobacteria,4B93M@82115|Rhizobiaceae 28211|Alphaproteobacteria D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3 TGS3_k127_1221908_0 314260.PB2503_08314 3.143e-287 893.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TSYQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 TGS3_k127_1221908_2 663932.KB902575_gene621 9.513e-46 175.0 COG0125@1|root,COG0125@2|Bacteria,1R6BR@1224|Proteobacteria,2UDBE@28211|Alphaproteobacteria 28211|Alphaproteobacteria F ATP binding - - - - - - - - - - - - Thymidylate_kin TGS3_k127_1221908_3 1357400.HMPREF2086_01297 4.9e-20 99.0 COG2020@1|root,COG2020@2|Bacteria,1RJNV@1224|Proteobacteria,42TNF@68525|delta/epsilon subdivisions 1224|Proteobacteria O Phospholipid methyltransferase - - - - - - - - - - - - PEMT TGS3_k127_1221908_1 1120705.FG95_02207 8.165e-184 587.0 COG2244@1|root,COG2244@2|Bacteria,1RC9S@1224|Proteobacteria,2U63T@28211|Alphaproteobacteria,2K3HG@204457|Sphingomonadales 204457|Sphingomonadales S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3 TGS3_k127_1227434_3 1121937.AUHJ01000012_gene2787 1.98e-25 111.0 COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,1S0CN@1236|Gammaproteobacteria,46AHX@72275|Alteromonadaceae 1236|Gammaproteobacteria P PhoD-like phosphatase, N-terminal domain - - - - - - - - - - - - PhoD,PhoD_N TGS3_k127_1227434_1 1247963.JPHU01000011_gene717 4.034e-206 653.0 COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,2TUMS@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q amidohydrolase - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 TGS3_k127_1227434_2 1247963.JPHU01000011_gene718 7.42e-108 365.0 COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,2U1V8@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q overlaps another CDS with the same product name - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 TGS3_k127_1227434_0 991905.SL003B_2748 9.511e-208 659.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2TRAU@28211|Alphaproteobacteria,4BPM2@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase TGS3_k127_1234327_1 582402.Hbal_1008 5.156e-83 282.0 COG3751@1|root,COG3751@2|Bacteria,1PVFH@1224|Proteobacteria,2V6V0@28211|Alphaproteobacteria,43ZP5@69657|Hyphomonadaceae 28211|Alphaproteobacteria O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_4 TGS3_k127_1234327_0 1161401.ASJA01000012_gene867 1.595e-110 367.0 COG2204@1|root,COG2204@2|Bacteria,1MWW5@1224|Proteobacteria,2TXAZ@28211|Alphaproteobacteria,43X5S@69657|Hyphomonadaceae 28211|Alphaproteobacteria T COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain pspF - - ko:K03974 - - - - ko00000,ko03000 - - - HTH_8,Sigma54_activat TGS3_k127_1234327_2 1123366.TH3_02875 2.771e-40 154.0 COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,2U6CN@28211|Alphaproteobacteria,2JRRW@204441|Rhodospirillales 204441|Rhodospirillales KT PspA/IM30 family - - - ko:K03969 - - - - ko00000 - - - PspA_IM30 TGS3_k127_1237505_3 1121271.AUCM01000012_gene2955 2.621e-44 168.0 COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Membrane omp28 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K09807 - - - - ko00000 - - - SIMPL TGS3_k127_1237505_0 1247963.JPHU01000012_gene916 7.016e-126 411.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG0235, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - - - - - - - - - - Aldolase_II TGS3_k127_1237505_1 450851.PHZ_c1180 1.229e-95 319.0 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2TSKN@28211|Alphaproteobacteria,2KFFH@204458|Caulobacterales 204458|Caulobacterales H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase TGS3_k127_1237505_2 1247963.JPHU01000009_gene2415 6.99e-80 279.0 COG2200@1|root,COG2200@2|Bacteria,1N34Q@1224|Proteobacteria,2UD2V@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL TGS3_k127_1245758_5 402881.Plav_0783 3.043e-62 218.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2TR40@28211|Alphaproteobacteria,1JNCC@119043|Rhodobiaceae 28211|Alphaproteobacteria J tRNA (Uracil-5-)-methyltransferase rumA - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - tRNA_U5-meth_tr TGS3_k127_1245758_3 1247963.JPHU01000005_gene291 4.584e-97 328.0 COG0500@1|root,COG2226@2|Bacteria,1NDFZ@1224|Proteobacteria,2TVI5@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 TGS3_k127_1245758_1 1174684.EBMC1_02605 7.457e-114 377.0 COG2267@1|root,COG2267@2|Bacteria,1RATF@1224|Proteobacteria,2TTCT@28211|Alphaproteobacteria,2K1SM@204457|Sphingomonadales 204457|Sphingomonadales I Alpha beta hydrolase - - - ko:K18092 ko00642,ko01100,ko01120,ko01220,map00642,map01100,map01120,map01220 - R05366 RC00752,RC00753 br01602,ko00000,ko00001,ko01000 - - - Abhydrolase_1,Abhydrolase_6 TGS3_k127_1245758_0 1120956.JHZK01000020_gene2104 1.013e-163 527.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2TQY2@28211|Alphaproteobacteria,1JN60@119043|Rhodobiaceae 28211|Alphaproteobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt TGS3_k127_1245758_4 509190.Cseg_3368 1.362e-87 294.0 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2TT1U@28211|Alphaproteobacteria,2KFPI@204458|Caulobacterales 204458|Caulobacterales H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx TGS3_k127_1245758_7 1247963.JPHU01000008_gene2846 1.225e-25 113.0 COG4103@1|root,COG4103@2|Bacteria,1NN2R@1224|Proteobacteria,2UK6A@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tellurite resistance protein TerB - - - - - - - - - - - - - TGS3_k127_1245758_2 1292034.OR37_02630 1.308e-101 342.0 COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria,2KFMD@204458|Caulobacterales 204458|Caulobacterales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B TGS3_k127_1245758_6 1282361.ABAC402_12845 2.686e-34 135.0 COG0189@1|root,COG0189@2|Bacteria,1RE49@1224|Proteobacteria,2U7EY@28211|Alphaproteobacteria,2KIJK@204458|Caulobacterales 204458|Caulobacterales HJ ligase activity - - - - - - - - - - - - - TGS3_k127_1290402_1 1333998.M2A_0888 5.496e-101 336.0 COG2267@1|root,COG2267@2|Bacteria,1N03H@1224|Proteobacteria,2U2EH@28211|Alphaproteobacteria 28211|Alphaproteobacteria I hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - 3.1.1.76 ko:K22250 - - - - ko00000,ko01000 - - - Abhydrolase_1 TGS3_k127_1290402_0 1121948.AUAC01000006_gene536 2.286e-259 810.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TVC3@28211|Alphaproteobacteria,43WBI@69657|Hyphomonadaceae 28211|Alphaproteobacteria I COG3243 Poly(3-hydroxyalkanoate) synthetase - - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1,PhaC_N TGS3_k127_1290402_3 1123059.KB823011_gene1685 1.641e-08 62.0 2AINJ@1|root,3194Z@2|Bacteria,1Q1TT@1224|Proteobacteria,2V9FR@28211|Alphaproteobacteria,440JP@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_1290402_2 1121949.AQXT01000002_gene418 1.071e-32 128.0 2DP2P@1|root,3309S@2|Bacteria,1N9NI@1224|Proteobacteria,2V6YZ@28211|Alphaproteobacteria,43YNY@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_1292170_0 314260.PB2503_12054 4.452e-202 649.0 COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,2TR7N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG0513 Superfamily II DNA and RNA helicases mgpS - 3.6.4.13 ko:K17675 - - - - ko00000,ko01000,ko03029 - - - Helicase_C TGS3_k127_1292170_3 1247963.JPHU01000001_gene2066 4.613e-16 81.0 COG1188@1|root,COG1188@2|Bacteria 2|Bacteria J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog)) hslR GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.23,5.4.99.24 ko:K04762,ko:K06179,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03110 - - - S4 TGS3_k127_1292170_2 517722.AEUE01000002_gene2078 9.501e-55 194.0 COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2U98K@28211|Alphaproteobacteria,2K4E8@204457|Sphingomonadales 204457|Sphingomonadales C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - ko:K05524 - - - - ko00000 - - - DUF3470,Fer4,Fer4_4 TGS3_k127_1292170_1 1037409.BJ6T_01720 4.01e-61 223.0 COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,2TTVP@28211|Alphaproteobacteria,3JR9K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K CarD-like/TRCF domain carD - - ko:K07736 - - - - ko00000,ko03000 - - - CarD_CdnL_TRCF TGS3_k127_1321208_3 1367847.JCM7686_3284 1.699e-10 62.0 COG2050@1|root,COG2050@2|Bacteria,1PP3J@1224|Proteobacteria,2U5E4@28211|Alphaproteobacteria,2PX26@265|Paracoccus 28211|Alphaproteobacteria Q Domain of unknown function (DUF4442) MA20_28520 - - - - - - - - - - - 4HBT TGS3_k127_1321208_0 1280944.HY17_13410 1.628e-236 741.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3 ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C TGS3_k127_1321208_1 1247963.JPHU01000007_gene1644 3.845e-95 321.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2TRD9@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD TGS3_k127_1321208_2 1110502.TMO_1851 1.714e-65 228.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,2JPW9@204441|Rhodospirillales 204441|Rhodospirillales H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA TGS3_k127_1327994_1 1317118.ATO8_02735 1.551e-49 196.0 COG4993@1|root,COG4993@2|Bacteria,1R6AV@1224|Proteobacteria,2TUKI@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Dehydrogenase - - - - - - - - - - - - - TGS3_k127_1327994_0 314260.PB2503_04162 3.59e-321 994.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 TGS3_k127_1327994_2 314260.PB2503_04157 1.375e-36 141.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria 28211|Alphaproteobacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ GO:0006457,GO:0008150,GO:0009987 - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG TGS3_k127_1364744_0 266779.Meso_1325 0.0 1098.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2TQPT@28211|Alphaproteobacteria,43ITV@69277|Phyllobacteriaceae 28211|Alphaproteobacteria CE Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg TGS3_k127_1364744_1 13689.BV96_02935 2.448e-29 122.0 COG3794@1|root,COG3794@2|Bacteria,1MZWU@1224|Proteobacteria,2UC7P@28211|Alphaproteobacteria,2K53H@204457|Sphingomonadales 204457|Sphingomonadales C Copper binding proteins, plastocyanin/azurin family - - - - - - - - - - - - Copper-bind TGS3_k127_1374497_10 1280946.HY29_12175 3.556e-60 215.0 COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2U6ZN@28211|Alphaproteobacteria,43XJN@69657|Hyphomonadaceae 28211|Alphaproteobacteria O Peroxiredoxin MA20_20905 - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - Redoxin TGS3_k127_1374497_14 1231392.OCGS_2066 2.326e-48 180.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2TTX4@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Belongs to the UPF0301 (AlgH) family MA20_18155 - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 TGS3_k127_1374497_21 1112216.JH594425_gene691 8.206e-28 131.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K35A@204457|Sphingomonadales 204457|Sphingomonadales T GAF domain - - - - - - - - - - - - EAL,GAF_2,GGDEF TGS3_k127_1374497_13 1089552.KI911559_gene3710 2.368e-49 185.0 COG1670@1|root,COG1670@2|Bacteria,1MVG4@1224|Proteobacteria,2TUIK@28211|Alphaproteobacteria,2JRYR@204441|Rhodospirillales 204441|Rhodospirillales J Acetyltransferase (GNAT) domain rimJ - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 TGS3_k127_1374497_6 371731.Rsw2DRAFT_1688 2.55e-96 334.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TR39@28211|Alphaproteobacteria,1FATY@1060|Rhodobacter 28211|Alphaproteobacteria S Belongs to the peptidase M16 family mpp - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C TGS3_k127_1374497_3 1411123.JQNH01000001_gene404 2.223e-128 426.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2TT0D@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Threonine synthase thrC GO:0003674,GO:0003824,GO:0004795,GO:0006082,GO:0006520,GO:0006566,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016311,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N TGS3_k127_1374497_18 314260.PB2503_06697 5.968e-31 123.0 COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2UBSC@28211|Alphaproteobacteria 28211|Alphaproteobacteria J 50S ribosomal protein L31 rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 TGS3_k127_1374497_17 1247963.JPHU01000004_gene479 1.464e-41 160.0 COG5317@1|root,COG5317@2|Bacteria,1RJIA@1224|Proteobacteria,2U9ID@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1465) MA20_18080 - - ko:K13592 ko04112,map04112 - - - ko00000,ko00001 - - - DUF1465 TGS3_k127_1374497_12 1247963.JPHU01000004_gene480 4.577e-51 189.0 COG4923@1|root,COG4923@2|Bacteria,1MY1R@1224|Proteobacteria,2U4CU@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Protein of unknown function (DUF429) - - - - - - - - - - - - DUF429 TGS3_k127_1374497_15 342113.DM82_4574 2.516e-48 177.0 2C4SR@1|root,32TC7@2|Bacteria,1RCZG@1224|Proteobacteria,2WA35@28216|Betaproteobacteria,1KEZQ@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_1374497_28 1042326.AZNV01000022_gene909 2.905e-05 52.0 COG5509@1|root,COG5509@2|Bacteria,1NG8P@1224|Proteobacteria,2UJB2@28211|Alphaproteobacteria,4BGTA@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1192) - - - - - - - - - - - - DUF1192 TGS3_k127_1374497_5 89187.ISM_09210 1.049e-109 366.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TR1J@28211|Alphaproteobacteria,46P9S@74030|Roseovarius 28211|Alphaproteobacteria C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases ppsC - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N TGS3_k127_1374497_7 314260.PB2503_02067 7.269e-82 279.0 COG3820@1|root,COG3820@2|Bacteria,1MVR2@1224|Proteobacteria,2TT8Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria MA20_20925 - - ko:K09987 - - - - ko00000 - - - DUF1013 TGS3_k127_1374497_11 1247963.JPHU01000003_gene1205 6.092e-54 199.0 COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,2TUA2@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) bacC - 1.1.1.159 ko:K00076 ko00121,map00121 - - - ko00000,ko00001,ko01000 - - - adh_short_C2 TGS3_k127_1374497_26 319003.Bra1253DRAFT_03591 1.086e-07 55.0 COG5570@1|root,COG5570@2|Bacteria,1NGRE@1224|Proteobacteria,2UJAX@28211|Alphaproteobacteria,3K16F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF465) - - - - - - - - - - - - DUF465 TGS3_k127_1374497_8 1479238.JQMZ01000001_gene117 3.639e-78 265.0 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2U5GN@28211|Alphaproteobacteria,43ZC7@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Flavoprotein ubiX - 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein TGS3_k127_1374497_23 391600.ABRU01000049_gene8 4.544e-20 101.0 COG5589@1|root,COG5589@2|Bacteria,1N6W5@1224|Proteobacteria,2UFIE@28211|Alphaproteobacteria,2KH5P@204458|Caulobacterales 204458|Caulobacterales S Protein of unknown function (DUF2390) - - - - - - - - - - - - DUF2390 TGS3_k127_1374497_25 1294273.roselon_01979 3.508e-12 73.0 COG5481@1|root,COG5481@2|Bacteria,1NG9U@1224|Proteobacteria,2UFXJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S small protein containing a coiled-coil domain MA20_03740 - - - - - - - - - - - DUF465 TGS3_k127_1374497_9 1479238.JQMZ01000001_gene1359 1.877e-64 225.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2U58D@28211|Alphaproteobacteria,43XS8@69657|Hyphomonadaceae 28211|Alphaproteobacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC TGS3_k127_1374497_4 1333998.M2A_2144 2.881e-124 409.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2TRSV@28211|Alphaproteobacteria,4BQ26@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp TGS3_k127_1374497_16 314254.OA2633_08004 2.316e-46 176.0 COG5590@1|root,COG5590@2|Bacteria,1MW25@1224|Proteobacteria,2U9ST@28211|Alphaproteobacteria,43XPJ@69657|Hyphomonadaceae 28211|Alphaproteobacteria S rpsU-divergently transcribed protein cOQ9 - - ko:K18587 - - - - ko00000 - - - COQ9 TGS3_k127_1374497_22 1247963.JPHU01000003_gene1480 6.344e-26 109.0 COG0828@1|root,COG0828@2|Bacteria,1MZA1@1224|Proteobacteria,2UC58@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 TGS3_k127_1374497_27 573065.Astex_3199 1.965e-05 48.0 COG5510@1|root,COG5510@2|Bacteria 2|Bacteria S response to toxic substance ecnA - - ko:K16348 - - - - ko00000,ko02000 9.B.13.1.1 - - Entericidin TGS3_k127_1374497_20 1126627.BAWE01000005_gene5593 4.395e-30 132.0 COG3713@1|root,COG3713@2|Bacteria,1REKJ@1224|Proteobacteria,2U37S@28211|Alphaproteobacteria,3JX3T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M MltA-interacting protein MipA - - - ko:K07274 - - - - ko00000,ko02000 9.B.99.1 - - MipA TGS3_k127_1374497_1 1449049.JONW01000010_gene3730 9.216e-196 616.0 COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,2TS5P@28211|Alphaproteobacteria,2KG62@204458|Caulobacterales 204458|Caulobacterales S VWA domain containing CoxE-like protein - - - ko:K09989 - - - - ko00000 - - - VWA_CoxE TGS3_k127_1374497_19 1211115.ALIQ01000013_gene2304 1.705e-30 126.0 COG5622@1|root,COG5622@2|Bacteria,1RIEJ@1224|Proteobacteria,2U7UE@28211|Alphaproteobacteria,3NBQC@45404|Beijerinckiaceae 28211|Alphaproteobacteria N Protein required for attachment to host cells - - - - - - - - - - - - Host_attach TGS3_k127_1374497_24 1247963.JPHU01000007_gene1594 3.05e-17 86.0 COG2198@1|root,COG2198@2|Bacteria 2|Bacteria T Histidine kinase - - 2.7.13.3 ko:K07647 ko02020,map02020 M00455 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - Hpt TGS3_k127_1374497_0 266779.Meso_0858 2.544e-201 637.0 COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2TRU8@28211|Alphaproteobacteria,43H2N@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF853) yjgR - - ko:K06915 - - - - ko00000 - - - DUF853 TGS3_k127_1374497_2 1280947.HY30_06020 1.792e-132 438.0 COG2133@1|root,COG2133@2|Bacteria,1R86D@1224|Proteobacteria,2U1Z1@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG2133 Glucose sorbosone dehydrogenases - - - - - - - - - - - - Cadherin,GSDH TGS3_k127_1382862_3 1535287.JP74_23075 1.333e-09 69.0 COG0607@1|root,COG0607@2|Bacteria,1RIGW@1224|Proteobacteria,2U9VJ@28211|Alphaproteobacteria,3N8MY@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria P Putative metallopeptidase - - - - - - - - - - - - DUF4344 TGS3_k127_1382862_1 1123267.JONN01000001_gene1239 1.888e-30 139.0 2C1YS@1|root,2ZD2Y@2|Bacteria 2|Bacteria S Protease prsW family - - - - - - - - - - - - PrsW-protease TGS3_k127_1407482_3 1207063.P24_08439 7.507e-113 370.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2JREA@204441|Rhodospirillales 204441|Rhodospirillales EQ Hydantoinase/oxoprolinase N-terminal region - - - - - - - - - - - - Hydant_A_N,Hydantoinase_A TGS3_k127_1407482_6 1238182.C882_2396 9.985e-75 259.0 COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,2TUA2@28211|Alphaproteobacteria,2JQ5Y@204441|Rhodospirillales 204441|Rhodospirillales IQ KR domain - - - - - - - - - - - - adh_short_C2 TGS3_k127_1407482_9 394221.Mmar10_1180 5.729e-44 171.0 COG4714@1|root,COG4714@2|Bacteria,1QV7Y@1224|Proteobacteria,2U2GT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_3 TGS3_k127_1407482_8 394221.Mmar10_1181 2.732e-51 192.0 COG4714@1|root,COG4714@2|Bacteria,1QV7Y@1224|Proteobacteria,2U2GT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_3 TGS3_k127_1407482_7 394221.Mmar10_2554 1.088e-57 209.0 COG3751@1|root,COG3751@2|Bacteria,1MY7Z@1224|Proteobacteria,2USN6@28211|Alphaproteobacteria,43Y9I@69657|Hyphomonadaceae 28211|Alphaproteobacteria O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_4 TGS3_k127_1407482_2 228405.HNE_3427 7.397e-124 414.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,43X4S@69657|Hyphomonadaceae 28211|Alphaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - - - - - - - - - - AMP-binding,AMP-binding_C TGS3_k127_1407482_5 648885.KB316284_gene4596 4.091e-80 274.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2TSBE@28211|Alphaproteobacteria,1JQX1@119045|Methylobacteriaceae 28211|Alphaproteobacteria V Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner lolD GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0031224,GO:0032991,GO:0033036,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran TGS3_k127_1407482_1 1247963.JPHU01000005_gene262 1.024e-127 422.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria 28211|Alphaproteobacteria M lipoprotein releasing system, transmembrane protein, LolC E family' lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD TGS3_k127_1407482_0 1382303.JPOM01000001_gene992 2.588e-215 676.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2TQQ4@28211|Alphaproteobacteria,2KF1Y@204458|Caulobacterales 204458|Caulobacterales J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b TGS3_k127_1407482_4 1123267.JONN01000002_gene263 4.623e-82 280.0 COG1028@1|root,COG1028@2|Bacteria,1MU73@1224|Proteobacteria,2TV6T@28211|Alphaproteobacteria,2K26C@204457|Sphingomonadales 204457|Sphingomonadales IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 TGS3_k127_1407482_10 1449076.JOOE01000003_gene3164 7.611e-06 51.0 COG0640@1|root,COG0640@2|Bacteria,1N2P4@1224|Proteobacteria,2UFNP@28211|Alphaproteobacteria,2K5QX@204457|Sphingomonadales 204457|Sphingomonadales K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 TGS3_k127_1408084_1 1333998.M2A_0354 1.998e-176 577.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,4BPPH@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M Transglycosylase pbpC - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase TGS3_k127_1408084_0 1545915.JROG01000004_gene1920 2.776e-210 665.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2TRP5@28211|Alphaproteobacteria,2K0N8@204457|Sphingomonadales 204457|Sphingomonadales J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C TGS3_k127_1408084_2 112098.XP_008606107.1 2.561e-69 253.0 COG0665@1|root,KOG2820@2759|Eukaryota 2759|Eukaryota E sarcosine oxidase activity - - - - - - - - - - - - DAO TGS3_k127_1408084_3 1122970.AUHC01000004_gene2235 5.33e-29 119.0 COG2274@1|root,COG2274@2|Bacteria,1MXTI@1224|Proteobacteria,2TUN0@28211|Alphaproteobacteria,2K1TC@204457|Sphingomonadales 204457|Sphingomonadales V ABC transporter, ATP-binding protein - - - ko:K02021 - - - - ko00000,ko02000 3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane,ABC_tran TGS3_k127_1419434_3 1280949.HAD_05725 1.179e-50 183.0 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2TS0S@28211|Alphaproteobacteria,43WCE@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM TGS3_k127_1419434_0 1234364.AMSF01000016_gene1581 1.536e-145 466.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,1RMF7@1236|Gammaproteobacteria,1X3GH@135614|Xanthomonadales 135614|Xanthomonadales O Belongs to the GST superfamily gst7 - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_C_2,GST_N TGS3_k127_1419434_2 228405.HNE_3333 1.605e-69 249.0 COG3698@1|root,COG3698@2|Bacteria,1NH9S@1224|Proteobacteria,2TT5B@28211|Alphaproteobacteria,43ZD3@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Phosphodiester glycosidase - - - - - - - - - - - - NAGPA TGS3_k127_1419434_5 582402.Hbal_0360 6.729e-24 107.0 COG0526@1|root,COG0526@2|Bacteria,1PANY@1224|Proteobacteria,2UYUN@28211|Alphaproteobacteria,43YMS@69657|Hyphomonadaceae 28211|Alphaproteobacteria CO Thioredoxin - - - - - - - - - - - - Thioredoxin TGS3_k127_1419434_8 1229204.AMYY01000005_gene1540 0.0001963 53.0 2DNE7@1|root,32X2M@2|Bacteria,1NA96@1224|Proteobacteria,2UFJ0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_1419434_1 190650.CC_3105 8.554e-99 334.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2KF7B@204458|Caulobacterales 204458|Caulobacterales E PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP TGS3_k127_1419434_7 1247963.JPHU01000009_gene2387 1.233e-15 81.0 COG5568@1|root,COG5568@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1150) MA20_24245 - - - - - - - - - - - DUF1150 TGS3_k127_1419434_4 1430440.MGMSRv2_4140 4.718e-46 171.0 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2U7B0@28211|Alphaproteobacteria,2JS6Q@204441|Rhodospirillales 204441|Rhodospirillales GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) ptsN - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 TGS3_k127_1419434_6 1121949.AQXT01000002_gene1849 6.792e-22 97.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2TV3J@28211|Alphaproteobacteria,43Y2N@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE TGS3_k127_142988_7 1082931.KKY_1931 4.438e-22 102.0 2DZ1B@1|root,34C3I@2|Bacteria,1P033@1224|Proteobacteria,2UV45@28211|Alphaproteobacteria,3N92G@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_142988_1 366602.Caul_5058 2.272e-131 426.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSM8@28211|Alphaproteobacteria,2KF6Y@204458|Caulobacterales 204458|Caulobacterales CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 - R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C TGS3_k127_142988_6 1479238.JQMZ01000001_gene193 2.068e-30 126.0 COG3807@1|root,COG3807@2|Bacteria,1RHM2@1224|Proteobacteria,2UA1R@28211|Alphaproteobacteria,43Y93@69657|Hyphomonadaceae 28211|Alphaproteobacteria S protein conserved in bacteria MA20_24010 - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - SH3_4 TGS3_k127_142988_4 314260.PB2503_03767 2.271e-82 277.0 COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,2TV8S@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length fabA - 4.2.1.59,5.3.3.14 ko:K01716 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639 RC00831,RC01078,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA TGS3_k127_142988_0 935840.JAEQ01000001_gene2709 1.593e-180 574.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2TQYV@28211|Alphaproteobacteria,43I2M@69277|Phyllobacteriaceae 28211|Alphaproteobacteria IQ Belongs to the beta-ketoacyl-ACP synthases family fabB GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt TGS3_k127_142988_2 1123059.KB823014_gene5 3.853e-125 405.0 COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2TSU4@28211|Alphaproteobacteria,43WHG@69657|Hyphomonadaceae 28211|Alphaproteobacteria I Enoyl- acyl-carrier-protein reductase NADH fabI GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 TGS3_k127_142988_5 1128421.JAGA01000002_gene101 6.487e-33 140.0 COG0584@1|root,COG0584@2|Bacteria,2NPNS@2323|unclassified Bacteria 2|Bacteria C PFAM Glycerophosphoryl diester phosphodiesterase glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD TGS3_k127_142988_3 1247963.JPHU01000002_gene2635 1.224e-120 394.0 COG0683@1|root,COG0683@2|Bacteria,1NQNR@1224|Proteobacteria,2UPVS@28211|Alphaproteobacteria 28211|Alphaproteobacteria E leucine binding - - - - - - - - - - - - - TGS3_k127_1435872_4 113395.AXAI01000029_gene2709 3.245e-142 460.0 COG1752@1|root,COG1752@2|Bacteria,1MVHW@1224|Proteobacteria,2TS4V@28211|Alphaproteobacteria,3JQYN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin TGS3_k127_1435872_7 1038859.AXAU01000003_gene5955 9.986e-103 342.0 COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,3JXIW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ KR domain - - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short,adh_short_C2 TGS3_k127_1435872_2 420324.KI911933_gene5399 1.873e-210 662.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2TQT2@28211|Alphaproteobacteria,1JRK5@119045|Methylobacteriaceae 28211|Alphaproteobacteria C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 TGS3_k127_1435872_0 247633.GP2143_14796 2.506e-307 957.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,1J8FD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C PQQ-like domain - - 1.1.2.8,1.1.9.1 ko:K00114,ko:K17760 ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130 - R05062,R05198,R05285 RC00087,RC00088,RC01039 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 TGS3_k127_1435872_6 1161401.ASJA01000014_gene1074 6.741e-116 391.0 COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,2TQSM@28211|Alphaproteobacteria,43WC6@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Serine hydrolase involved in the detoxification of formaldehyde fghA - 3.1.2.12 ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R00527 RC00167,RC00320 ko00000,ko00001,ko01000 - CE1 - Esterase TGS3_k127_1435872_1 1333998.M2A_1344 9.413e-214 668.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TT67@28211|Alphaproteobacteria,4BPTE@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily adhC - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N TGS3_k127_1435872_11 1247963.JPHU01000001_gene1978 2.706e-26 117.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2UDUF@28211|Alphaproteobacteria 28211|Alphaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme TGS3_k127_1435872_9 1123229.AUBC01000007_gene249 1.169e-72 261.0 COG4961@1|root,COG4961@2|Bacteria,1QV5Z@1224|Proteobacteria,2TWAQ@28211|Alphaproteobacteria,3JSGE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad TGS3_k127_1435872_10 1411123.JQNH01000001_gene2277 1.511e-67 245.0 COG4961@1|root,COG4961@2|Bacteria,1RA6J@1224|Proteobacteria,2U6PB@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad TGS3_k127_1435872_5 1280947.HY30_10910 5.366e-118 386.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2TQTH@28211|Alphaproteobacteria,43WNA@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 TGS3_k127_1435872_8 1411123.JQNH01000001_gene1774 9.807e-94 313.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2TQXM@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC TGS3_k127_1435872_3 330214.NIDE1172 3.177e-172 552.0 COG1805@1|root,COG4402@1|root,COG1805@2|Bacteria,COG4402@2|Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2330) nqrB GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 ko:K00347,ko:K21163 ko01059,ko01130,map01059,map01130 M00824 - - ko00000,ko00001,ko00002,ko01000 - - - DUF2330,NQR2_RnfD_RnfE TGS3_k127_1450225_0 1123269.NX02_24365 7.786e-239 763.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2TTFY@28211|Alphaproteobacteria,2K075@204457|Sphingomonadales 204457|Sphingomonadales P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec TGS3_k127_1450225_3 1247963.JPHU01000012_gene869 1.601e-88 304.0 COG2267@1|root,COG2267@2|Bacteria,1RATF@1224|Proteobacteria,2VFU0@28211|Alphaproteobacteria 28211|Alphaproteobacteria I TAP-like protein - - - - - - - - - - - - Abhydrolase_1 TGS3_k127_1450225_1 1247963.JPHU01000012_gene868 2.993e-196 621.0 COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,2U5M0@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 TGS3_k127_1450225_4 627192.SLG_11520 1.145e-72 252.0 28IPG@1|root,2Z8PF@2|Bacteria,1P8KM@1224|Proteobacteria,2U8ZT@28211|Alphaproteobacteria,2K4I9@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - TGS3_k127_1450225_2 1121939.L861_22615 2.398e-97 328.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria,1XNFI@135619|Oceanospirillales 135619|Oceanospirillales S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red TGS3_k127_1468334_2 1265313.HRUBRA_01460 7.661e-39 151.0 COG1538@1|root,COG1538@2|Bacteria,1R705@1224|Proteobacteria,1S0X1@1236|Gammaproteobacteria 1236|Gammaproteobacteria MU PFAM Outer membrane efflux protein - - - - - - - - - - - - OEP TGS3_k127_1468334_1 1265313.HRUBRA_01459 1.694e-134 436.0 COG0845@1|root,COG0845@2|Bacteria,1PZ6R@1224|Proteobacteria,1RRGC@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG0845 Membrane-fusion protein - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 TGS3_k127_1468334_0 1247963.JPHU01000001_gene1945 2.765e-162 524.0 COG2274@1|root,COG2274@2|Bacteria,1MXTI@1224|Proteobacteria,2TUN0@28211|Alphaproteobacteria 28211|Alphaproteobacteria V abc transporter atp-binding protein - - - ko:K02021 - - - - ko00000,ko02000 3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane,ABC_tran TGS3_k127_147490_4 1479238.JQMZ01000001_gene304 0.0008002 42.0 COG4391@1|root,COG4391@2|Bacteria,1N7F4@1224|Proteobacteria,2UFVF@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - zf-CHCC TGS3_k127_147490_0 1247963.JPHU01000012_gene924 3.975e-110 374.0 COG1668@1|root,COG1668@2|Bacteria,1R62N@1224|Proteobacteria,2U1RZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria CP COG1668 ABC-type Na efflux pump, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 TGS3_k127_147490_1 1247963.JPHU01000012_gene925 7.567e-103 344.0 COG4152@1|root,COG4152@2|Bacteria,1QUPV@1224|Proteobacteria,2TWB4@28211|Alphaproteobacteria 28211|Alphaproteobacteria S abc transporter atp-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 TGS3_k127_147490_2 1247963.JPHU01000003_gene1491 4.102e-62 219.0 COG1384@1|root,COG1384@2|Bacteria,1MV32@1224|Proteobacteria,2TQYH@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04566 ko00970,map00970 M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1f TGS3_k127_1489872_2 1449069.JMLO01000001_gene2119 2.483e-10 70.0 COG3126@1|root,COG3126@2|Bacteria,2HKKJ@201174|Actinobacteria,4G8G3@85025|Nocardiaceae 201174|Actinobacteria S Type III secretion system lipoprotein chaperone (YscW) - - - ko:K09914 - - - - ko00000 - - - YscW TGS3_k127_1489872_0 768066.HELO_3309 2.444e-60 215.0 COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,1SE7Z@1236|Gammaproteobacteria,1XK32@135619|Oceanospirillales 135619|Oceanospirillales Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 TGS3_k127_1489872_1 1111730.ATTM01000006_gene2581 1.311e-11 72.0 COG4704@1|root,COG4704@2|Bacteria,4NUS8@976|Bacteroidetes,1I45Z@117743|Flavobacteriia,2NX3W@237|Flavobacterium 976|Bacteroidetes S Uncharacterized protein conserved in bacteria (DUF2141) - - - - - - - - - - - - DUF2141 TGS3_k127_1490320_2 1282876.BAOK01000001_gene3573 2.889e-173 578.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2TQJZ@28211|Alphaproteobacteria,4BP6D@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L PD-(D/E)XK nuclease superfamily addA - 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C TGS3_k127_1490320_10 1114964.L485_20295 2.295e-46 170.0 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,2K589@204457|Sphingomonadales 204457|Sphingomonadales O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin TGS3_k127_1490320_3 1247963.JPHU01000002_gene2610 5.073e-137 448.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2TR64@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_M TGS3_k127_1490320_4 314260.PB2503_04582 1.501e-117 386.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2TRSH@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans TGS3_k127_1490320_5 1247963.JPHU01000002_gene2608 2.578e-106 351.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2TQN2@28211|Alphaproteobacteria 28211|Alphaproteobacteria E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA TGS3_k127_1490320_1 1161401.ASJA01000023_gene164 1.259e-182 587.0 COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,2UPPD@28211|Alphaproteobacteria,43ZBQ@69657|Hyphomonadaceae 28211|Alphaproteobacteria I Belongs to the type-B carboxylesterase lipase family - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase TGS3_k127_1490320_13 207559.Dde_1560 3.566e-06 55.0 COG1846@1|root,COG1846@2|Bacteria,1PRYR@1224|Proteobacteria,432T3@68525|delta/epsilon subdivisions,2WYB3@28221|Deltaproteobacteria,2MFAD@213115|Desulfovibrionales 28221|Deltaproteobacteria K Transcriptional regulator - - - - - - - - - - - - MarR_2 TGS3_k127_1490320_6 983920.Y88_0048 7.086e-92 315.0 COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,2TUF8@28211|Alphaproteobacteria,2K6MZ@204457|Sphingomonadales 204457|Sphingomonadales I Fatty acid desaturase - - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase TGS3_k127_1490320_0 314260.PB2503_04597 3.178e-222 694.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2TSHK@28211|Alphaproteobacteria 28211|Alphaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP TGS3_k127_1490320_8 118163.Ple7327_2561 2.611e-84 287.0 COG3751@1|root,COG3751@2|Bacteria,1G4YQ@1117|Cyanobacteria,3VM0G@52604|Pleurocapsales 1117|Cyanobacteria O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_3 TGS3_k127_1490320_9 1279038.KB907342_gene2606 5.416e-57 207.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2U7CH@28211|Alphaproteobacteria,2JSD3@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI TGS3_k127_1490320_11 1333998.M2A_2824 1.378e-38 147.0 COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2UBR5@28211|Alphaproteobacteria,4BQH7@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himD GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding TGS3_k127_1490320_7 1122218.KB893653_gene1299 2.282e-89 301.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2TRWR@28211|Alphaproteobacteria,1JS5S@119045|Methylobacteriaceae 28211|Alphaproteobacteria H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran TGS3_k127_1490320_15 1247963.JPHU01000011_gene811 0.0002035 46.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2TS87@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 TGS3_k127_151773_0 1122970.AUHC01000005_gene2018 0.0 1379.0 COG0365@1|root,COG0604@1|root,COG1024@1|root,COG0365@2|Bacteria,COG0604@2|Bacteria,COG1024@2|Bacteria,1MXIK@1224|Proteobacteria,2U43I@28211|Alphaproteobacteria,2K2UF@204457|Sphingomonadales 204457|Sphingomonadales CI Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ADH_zinc_N,AMP-binding,AMP-binding_C,ECH_1 TGS3_k127_1527281_0 1247963.JPHU01000005_gene267 0.0 1314.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR3C@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Pyruvate phosphate dikinase ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N TGS3_k127_1527281_6 1247963.JPHU01000005_gene266 3.254e-44 170.0 COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,2TT15@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Cell wall hydrolyses involved in spore germination sleB - - - - - - - - - - - Hydrolase_2 TGS3_k127_1527281_3 1280950.HJO_15908 5.65e-112 372.0 COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,2TS2E@28211|Alphaproteobacteria,43XC7@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA ybbB - - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese TGS3_k127_1527281_1 1280950.HJO_15903 1.854e-149 483.0 COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,2TR91@28211|Alphaproteobacteria,43X4B@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C,Pyr_redox_2 TGS3_k127_1527281_5 1247963.JPHU01000012_gene876 2.058e-51 191.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2TR8J@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the GcvT family ygfZ - - ko:K06980,ko:K22073 - - - - ko00000,ko01000,ko03016,ko03029 - - - GCV_T,GCV_T_C TGS3_k127_1527281_7 1294143.H681_08245 8.258e-30 126.0 2E31J@1|root,32Y1Y@2|Bacteria,1N745@1224|Proteobacteria,1SCMM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S MAPEG family - - - - - - - - - - - - MAPEG TGS3_k127_1527281_4 1280954.HPO_11534 4.237e-69 243.0 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,43XGD@69657|Hyphomonadaceae 28211|Alphaproteobacteria L glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco TGS3_k127_1527281_2 32042.PstZobell_01762 1.442e-138 449.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1Z1IP@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria I COG0332 3-oxoacyl- acyl-carrier-protein synthase III fabH - 2.3.1.207 ko:K16872 - - - - ko00000,ko01000 - - - ACP_syn_III,ACP_syn_III_C TGS3_k127_152945_3 1161401.ASJA01000001_gene312 2.242e-32 131.0 COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2U77Q@28211|Alphaproteobacteria,43XQ7@69657|Hyphomonadaceae 28211|Alphaproteobacteria FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.1,3.5.4.3,3.5.4.33 ko:K01485,ko:K01487,ko:K11991 ko00230,ko00240,ko00330,ko01100,map00230,map00240,map00330,map01100 - R00974,R01411,R01676,R02922,R10223 RC00074,RC00204,RC00477,RC00514,RC00809 ko00000,ko00001,ko01000,ko03016 - - - MafB19-deam,dCMP_cyt_deam_1 TGS3_k127_152945_1 338963.Pcar_1757 5.866e-63 224.0 COG2227@1|root,COG2227@2|Bacteria,1QTWG@1224|Proteobacteria,42XHD@68525|delta/epsilon subdivisions,2WT8V@28221|Deltaproteobacteria,43VMP@69541|Desulfuromonadales 28221|Deltaproteobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_23 TGS3_k127_152945_0 1247963.JPHU01000011_gene828 1.92e-105 347.0 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2TQP2@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 TGS3_k127_152945_4 228405.HNE_2945 0.0002089 49.0 2EFUM@1|root,339KS@2|Bacteria,1NGG6@1224|Proteobacteria,2UJA7@28211|Alphaproteobacteria,43YS6@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF4169) - - - - - - - - - - - - DUF4169 TGS3_k127_152945_2 1280952.HJA_10885 5.392e-53 188.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2U70Y@28211|Alphaproteobacteria,43XF0@69657|Hyphomonadaceae 28211|Alphaproteobacteria L Methyltransferase rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 TGS3_k127_153634_3 1333998.M2A_0736 6.622e-59 212.0 COG0778@1|root,COG0778@2|Bacteria,1NTK9@1224|Proteobacteria,2TR3E@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Nitroreductase - - - - - - - - - - - - Nitroreductase TGS3_k127_153634_4 1161401.ASJA01000015_gene941 1.083e-50 192.0 COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,2TUJR@28211|Alphaproteobacteria,440KI@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans TGS3_k127_153634_2 414684.RC1_2582 3.346e-71 248.0 COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,2TSCG@28211|Alphaproteobacteria,2JRQD@204441|Rhodospirillales 204441|Rhodospirillales J COG0564 Pseudouridylate synthases, 23S RNA-specific - - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 TGS3_k127_153634_0 886293.Sinac_7137 1.841e-134 444.0 COG2374@1|root,COG2374@2|Bacteria,2J1PX@203682|Planctomycetes 203682|Planctomycetes S PFAM Endonuclease Exonuclease phosphatase - - - - - - - - - - - - Exo_endo_phos TGS3_k127_153634_5 551275.KB899546_gene1995 3.075e-33 132.0 COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2UBXX@28211|Alphaproteobacteria,43Y97@69657|Hyphomonadaceae 28211|Alphaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02113,ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE_N TGS3_k127_153634_1 1122613.ATUP01000001_gene1164 4.509e-85 283.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2TRGP@28211|Alphaproteobacteria,43WIX@69657|Hyphomonadaceae 28211|Alphaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N TGS3_k127_1583222_2 1247963.JPHU01000012_gene864 1.831e-82 304.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria tamB - - ko:K09800 - - - - ko00000,ko02000 - - - TamB TGS3_k127_1583222_1 864051.BurJ1DRAFT_0012 2.824e-124 407.0 COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,2VIKG@28216|Betaproteobacteria,1KJMB@119065|unclassified Burkholderiales 28216|Betaproteobacteria S FAD dependent oxidoreductase - - 1.4.3.3 ko:K00273 ko00260,ko00311,ko00330,ko00472,ko01100,ko01130,ko04146,map00260,map00311,map00330,map00472,map01100,map01130,map04146 - R00366,R02457,R02894,R02923,R04221,R07400 RC00006,RC00018,RC00135 ko00000,ko00001,ko01000 - - - DAO TGS3_k127_1583222_3 314260.PB2503_10479 3.791e-50 186.0 COG0727@1|root,COG0727@2|Bacteria,1N5PC@1224|Proteobacteria,2UFEE@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative zinc- or iron-chelating domain - - - ko:K06940 - - - - ko00000 - - - CxxCxxCC TGS3_k127_1583222_0 1247963.JPHU01000006_gene156 1.095e-173 553.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2TQU7@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans TGS3_k127_1612942_6 107635.AZUO01000001_gene1459 4.619e-09 57.0 COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,2TS4S@28211|Alphaproteobacteria,36X85@31993|Methylocystaceae 28211|Alphaproteobacteria S YmdB-like protein MA20_17970 - - ko:K09769 - - - - ko00000 - - - YmdB TGS3_k127_1612942_1 278963.ATWD01000001_gene1277 1.138e-117 391.0 COG3503@1|root,COG3503@2|Bacteria,3Y6EK@57723|Acidobacteria,2JKNW@204432|Acidobacteriia 204432|Acidobacteriia S Protein of unknown function (DUF1624) - - - - - - - - - - - - DUF1624 TGS3_k127_1612942_7 551115.Aazo_4774 8.738e-06 57.0 COG0457@1|root,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1HJ4A@1161|Nostocales 1117|Cyanobacteria O Tetratricopeptide repeat - - - - - - - - - - - - FGE-sulfatase,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 TGS3_k127_1612942_5 1121949.AQXT01000002_gene3021 1.133e-35 139.0 COG1917@1|root,COG1917@2|Bacteria,1PVH1@1224|Proteobacteria,2V6W5@28211|Alphaproteobacteria,43YDZ@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 TGS3_k127_1612942_4 1282361.ABAC402_11175 2.765e-42 165.0 29EN4@1|root,301K2@2|Bacteria,1RD2A@1224|Proteobacteria,2U7UG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_1612942_2 1282361.ABAC402_11180 4.181e-99 334.0 COG2146@1|root,COG2717@1|root,COG2146@2|Bacteria,COG2717@2|Bacteria 2|Bacteria C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain yedZ_1 - 1.7.1.15 ko:K00363,ko:K05710,ko:K17247 ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220 M00530,M00545 R00787,R06782,R06783 RC00098,RC00176 br01602,ko00000,ko00001,ko00002,ko01000 - - - FMN_bind,Ferric_reduct,Rieske TGS3_k127_1612942_8 911045.PSE_1110 2.678e-05 49.0 2ESCG@1|root,33JX8@2|Bacteria,1NG95@1224|Proteobacteria,2UJKR@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_1612942_3 246197.MXAN_5306 8.011e-48 178.0 COG1670@1|root,COG1670@2|Bacteria,1RHBD@1224|Proteobacteria 1224|Proteobacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 TGS3_k127_1612942_0 247634.GPB2148_1965 2.455e-243 769.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1J52J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF885 TGS3_k127_1636133_3 1000565.METUNv1_01594 1.646e-26 120.0 COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,2KW83@206389|Rhodocyclales 206389|Rhodocyclales O Cytochrome c-type biogenesis protein - - - ko:K02200 - - - - ko00000 - - - TPR_16 TGS3_k127_1636133_2 1370122.JHXQ01000001_gene502 9.234e-44 163.0 COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2U96P@28211|Alphaproteobacteria,4BEZ9@82115|Rhizobiaceae 28211|Alphaproteobacteria O subunit of a heme lyase cycL - - ko:K02200 - - - - ko00000 - - - CcmH TGS3_k127_1636133_1 394221.Mmar10_1658 5.436e-63 221.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2TSEW@28211|Alphaproteobacteria,43YKV@69657|Hyphomonadaceae 28211|Alphaproteobacteria CO Thiol disulfide interchange protein ccmG - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,Redoxin TGS3_k127_1636133_0 1089551.KE386572_gene2842 1.061e-194 628.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2TRNG@28211|Alphaproteobacteria,4BP8T@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O TIGRFAM c-type cytochrome biogenesis protein CcmF ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm TGS3_k127_1636133_4 1380394.JADL01000002_gene1129 0.0002841 48.0 2DSFG@1|root,33FYD@2|Bacteria 2|Bacteria S Heme exporter protein D (CcmD) - - - - - - - - - - - - CcmD TGS3_k127_1636133_5 1123060.JONP01000014_gene4188 0.0005953 46.0 COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2TVBT@28211|Alphaproteobacteria,2JRQJ@204441|Rhodospirillales 204441|Rhodospirillales O once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system ccmA - 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - - ABC_tran TGS3_k127_1654057_5 314260.PB2503_10534 2.321e-95 319.0 COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,2TVFK@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - DUF3473,Polysacc_deac_1 TGS3_k127_1654057_6 1283300.ATXB01000001_gene1496 6.559e-82 284.0 COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,1T22W@1236|Gammaproteobacteria,1XG6P@135618|Methylococcales 135618|Methylococcales V FemAB family - - - - - - - - - - - - Acetyltransf_6 TGS3_k127_1654057_4 1158182.KB905024_gene58 4.454e-100 342.0 COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1WWKU@135613|Chromatiales 135613|Chromatiales M Sugar transferase, PEP-CTERM EpsH1 system associated - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4 TGS3_k127_1654057_2 394221.Mmar10_1113 1.268e-121 398.0 COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,2TYHX@28211|Alphaproteobacteria,43WZF@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Carbon-nitrogen hydrolase - - 3.5.5.1 ko:K01501 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 - R00540,R01887,R03093,R03542,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC02811 ko00000,ko00001,ko01000 - - - CN_hydrolase TGS3_k127_1654057_9 1547437.LL06_19070 2.212e-31 130.0 COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2UBRM@28211|Alphaproteobacteria,43MJP@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S YHS domain protein - - - - - - - - - - - - YHS TGS3_k127_1654057_1 402881.Plav_2240 8.564e-139 449.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2TQNC@28211|Alphaproteobacteria,1JNJF@119043|Rhodobiaceae 28211|Alphaproteobacteria H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - - Coprogen_oxidas TGS3_k127_1654057_8 394221.Mmar10_0735 1.728e-43 165.0 COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2U78W@28211|Alphaproteobacteria,43XVM@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide trmL - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase TGS3_k127_1654057_7 1247963.JPHU01000001_gene1971 8.677e-70 254.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2TTT2@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N TGS3_k127_1654057_0 314260.PB2503_10629 4.604e-203 649.0 COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2TSZ3@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - ko:K00410,ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrom_C1,Cytochrome_B TGS3_k127_1654057_3 314260.PB2503_10634 1.707e-100 338.0 COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2TUHX@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cytochrome c1 petC - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C1 TGS3_k127_1654057_11 502025.Hoch_2273 2.855e-05 51.0 COG3793@1|root,COG3793@2|Bacteria 2|Bacteria P PFAM Mo-dependent nitrogenase - - - ko:K05793 - - - - ko00000 - - - TerB TGS3_k127_1662504_2 1161401.ASJA01000005_gene2399 2.17e-77 268.0 COG4805@1|root,COG4805@2|Bacteria,1R84Q@1224|Proteobacteria,2TT6N@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 TGS3_k127_1662504_1 1247963.JPHU01000006_gene178 9.435e-85 296.0 COG0477@1|root,COG2814@2|Bacteria,1MVSC@1224|Proteobacteria,2TXB0@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr TGS3_k127_1662504_0 402881.Plav_3302 2.805e-169 535.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2TR9U@28211|Alphaproteobacteria,1JMYR@119043|Rhodobiaceae 28211|Alphaproteobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon TGS3_k127_168146_3 1280949.HAD_11765 7.46e-50 184.0 COG0457@1|root,COG0457@2|Bacteria,1N9D5@1224|Proteobacteria,2UIQ4@28211|Alphaproteobacteria,43YUT@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - TGS3_k127_168146_0 551275.KB899550_gene655 2.228e-223 707.0 COG2268@1|root,COG2268@2|Bacteria,1P50K@1224|Proteobacteria,2TTVY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria MA20_13940 - - - - - - - - - - - Band_7,Flot TGS3_k127_168146_4 1121013.P873_08335 4.482e-42 162.0 COG1585@1|root,COG1585@2|Bacteria,1RG29@1224|Proteobacteria,1S7HI@1236|Gammaproteobacteria 1236|Gammaproteobacteria OU Protein of unknown function (DUF1449) - - - - - - - - - - - - DUF1449 TGS3_k127_168146_1 1247963.JPHU01000002_gene2472 2.987e-208 656.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2TRKY@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt TGS3_k127_168146_2 314260.PB2503_02667 1.146e-73 251.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2TQNG@28211|Alphaproteobacteria 28211|Alphaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N TGS3_k127_1706738_0 314254.OA2633_15025 4.866e-79 270.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,2TSRR@28211|Alphaproteobacteria,43X56@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA - - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus TGS3_k127_1706738_1 394221.Mmar10_3077 1.193e-61 224.0 COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,2U5RA@28211|Alphaproteobacteria,43XXY@69657|Hyphomonadaceae 28211|Alphaproteobacteria S TraB family - - - ko:K09973 - - - - ko00000 - - - TraB TGS3_k127_1706738_3 450851.PHZ_c2933 4.306e-19 91.0 COG1476@1|root,COG1476@2|Bacteria,1N6SS@1224|Proteobacteria,2UFFG@28211|Alphaproteobacteria,2KH6R@204458|Caulobacterales 204458|Caulobacterales K Transcriptional regulator - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 TGS3_k127_1706738_2 1038859.AXAU01000049_gene2266 4.422e-59 207.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2TRIJ@28211|Alphaproteobacteria,3JTAW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G phosphoglucomutase phosphomannomutase alpha beta alpha domain I algC - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV TGS3_k127_1712251_0 1247963.JPHU01000008_gene2856 2.821e-198 637.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran TGS3_k127_1712251_1 1280950.HJO_02940 8.833e-37 144.0 COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,2VF2W@28211|Alphaproteobacteria,43WSP@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 TGS3_k127_1732789_0 95619.PM1_0227045 2.603e-131 428.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3 ko:K01897,ko:K18661 ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280,R03383 RC00004,RC00014,RC00137 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C TGS3_k127_1732789_1 595460.RRSWK_03509 1.488e-40 160.0 COG4798@1|root,COG4798@2|Bacteria,2IZ87@203682|Planctomycetes 203682|Planctomycetes S PFAM Methyltransferase type 11 - - - - - - - - - - - - DrsE,Methyltransf_25 TGS3_k127_1732789_2 545243.BAEV01000220_gene346 2.588e-17 81.0 2DP8N@1|root,3311E@2|Bacteria,1VG5U@1239|Firmicutes,24TG5@186801|Clostridia,36NF7@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - TGS3_k127_1756875_1 247634.GPB2148_1950 4.793e-140 459.0 COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,1RR99@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF1501 TGS3_k127_1756875_0 247633.GP2143_08544 1.641e-145 482.0 COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,1RR2N@1236|Gammaproteobacteria 1236|Gammaproteobacteria G protein conserved in bacteria - - - - - - - - - - - - DUF1800 TGS3_k127_1756875_2 1112212.JH584235_gene2945 1.382e-105 353.0 COG0630@1|root,COG0630@2|Bacteria,1QUJ6@1224|Proteobacteria,2TW2D@28211|Alphaproteobacteria,2K02G@204457|Sphingomonadales 204457|Sphingomonadales NU IV secretion system protein - - - ko:K03196 ko03070,ko05120,map03070,map05120 M00333,M00564 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - T2SSE TGS3_k127_1756875_3 1282362.AEAC466_10315 2.323e-62 221.0 COG2948@1|root,COG2948@2|Bacteria,1MU7U@1224|Proteobacteria,2VEQH@28211|Alphaproteobacteria,2KI83@204458|Caulobacterales 204458|Caulobacterales U Bacterial conjugation TrbI-like protein - - - - - - - - - - - - TrbI TGS3_k127_1763662_1 391600.ABRU01000061_gene2033 2.554e-71 244.0 COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2TRRE@28211|Alphaproteobacteria,2KFJ8@204458|Caulobacterales 204458|Caulobacterales O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome TGS3_k127_1763662_2 1282360.ABAC460_03495 7.853e-45 179.0 COG4655@1|root,COG4655@2|Bacteria,1RGJG@1224|Proteobacteria,2U32U@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad TGS3_k127_1763662_3 266779.Meso_0608 5.049e-18 91.0 COG4961@1|root,COG4963@1|root,COG4961@2|Bacteria,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2TUDS@28211|Alphaproteobacteria,43H2T@69277|Phyllobacteriaceae 28211|Alphaproteobacteria U AAA domain - - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31,CBP_BcsQ,TadE TGS3_k127_1763662_4 1197706.AKKK01000047_gene3395 0.000737 48.0 COG4961@1|root,COG4961@2|Bacteria,2GWMA@201174|Actinobacteria 201174|Actinobacteria U TadE-like protein - - - - - - - - - - - - TadE TGS3_k127_1763662_0 551789.ATVJ01000001_gene1215 1.472e-187 595.0 COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2TRXC@28211|Alphaproteobacteria,43WWB@69657|Hyphomonadaceae 28211|Alphaproteobacteria O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small TGS3_k127_1777574_1 1247963.JPHU01000004_gene575 2.897e-67 243.0 COG2267@1|root,COG2267@2|Bacteria,1MWDA@1224|Proteobacteria,2TSZ4@28211|Alphaproteobacteria 28211|Alphaproteobacteria I alpha, beta pldB - 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 TGS3_k127_1777574_3 1247963.JPHU01000004_gene576 6.192e-13 74.0 COG3255@1|root,COG3255@2|Bacteria 2|Bacteria I Sterol carrier protein - - - - - - - - - - - - SCP2 TGS3_k127_1777574_0 582402.Hbal_2993 4.019e-84 289.0 COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,2U5HN@28211|Alphaproteobacteria,43X66@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Methyltransferase - - - - - - - - - - - - - TGS3_k127_1777574_2 1247963.JPHU01000004_gene578 3.707e-54 194.0 COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,2U96D@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K04080 - - - - ko00000,ko03110 - - - HSP20 TGS3_k127_1777642_4 1110502.TMO_2795 2.088e-59 210.0 COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2U7C4@28211|Alphaproteobacteria,2JS6U@204441|Rhodospirillales 204441|Rhodospirillales L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H TGS3_k127_1777642_3 1231190.NA8A_15826 7.607e-95 321.0 COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2TS6D@28211|Alphaproteobacteria,43GPN@69277|Phyllobacteriaceae 28211|Alphaproteobacteria F Belongs to the pseudomonas-type ThrB family thrB - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH TGS3_k127_1777642_2 1054213.HMPREF9946_01985 6.539e-102 342.0 COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2TRNR@28211|Alphaproteobacteria,2JPYR@204441|Rhodospirillales 204441|Rhodospirillales IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB TGS3_k127_1777642_5 1247963.JPHU01000015_gene1112 3.464e-45 169.0 28PM9@1|root,2ZCAC@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - TGS3_k127_1777642_0 314260.PB2503_02222 1.157e-207 660.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2TS3Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d TGS3_k127_1777642_1 1122137.AQXF01000005_gene1195 1.136e-102 347.0 COG1629@1|root,COG1629@2|Bacteria,1QYF4@1224|Proteobacteria,2TXUT@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,TonB_dep_Rec TGS3_k127_1788575_8 314260.PB2503_02162 1.536e-28 119.0 COG5349@1|root,COG5349@2|Bacteria,1N0WU@1224|Proteobacteria,2UCE7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF983) - - - - - - - - - - - - DUF983 TGS3_k127_1788575_7 1125973.JNLC01000014_gene2645 9.471e-44 168.0 COG3346@1|root,COG3346@2|Bacteria,1MWWG@1224|Proteobacteria,2U0N5@28211|Alphaproteobacteria,3JS5J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S SURF1 family surf1 - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 TGS3_k127_1788575_6 1247963.JPHU01000001_gene2045 1.547e-49 180.0 COG5395@1|root,COG5395@2|Bacteria 2|Bacteria T membrane protein (DUF2306) - - - - - - - - - - - - DUF2306 TGS3_k127_1788575_4 1121124.JNIX01000016_gene2092 1.503e-64 230.0 COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria,2KHP5@204458|Caulobacterales 204458|Caulobacterales G HpcH/HpaI aldolase/citrate lyase family - - - - - - - - - - - - HpcH_HpaI TGS3_k127_1788575_2 1469613.JT55_13230 1.369e-100 338.0 COG1216@1|root,COG1216@2|Bacteria,1RHVX@1224|Proteobacteria,2UA24@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Glycosyl transferase family 21 - - - - - - - - - - - - Glycos_transf_2 TGS3_k127_1788575_5 1247963.JPHU01000002_gene2498 1.248e-54 212.0 COG1807@1|root,COG1807@2|Bacteria,1NVNI@1224|Proteobacteria 1224|Proteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 TGS3_k127_1788575_0 1247963.JPHU01000002_gene2515 1.243e-235 738.0 COG1232@1|root,COG1232@2|Bacteria,1MX35@1224|Proteobacteria,2TU7I@28211|Alphaproteobacteria 28211|Alphaproteobacteria H amine oxidase - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 TGS3_k127_1788575_1 864069.MicloDRAFT_00012960 2.201e-116 385.0 COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,2TRM0@28211|Alphaproteobacteria,1JSN6@119045|Methylobacteriaceae 28211|Alphaproteobacteria M PFAM NAD-dependent epimerase dehydratase - - 4.1.1.35 ko:K08678 ko00520,ko01100,map00520,map01100 M00361 R01384 RC00508 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd TGS3_k127_1788575_3 450851.PHZ_c2343 2.092e-97 322.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,2TSRR@28211|Alphaproteobacteria,2KEXC@204458|Caulobacterales 204458|Caulobacterales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA - - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus TGS3_k127_1799484_2 1101195.Meth11DRAFT_1584 1.208e-36 148.0 COG0438@1|root,COG0438@2|Bacteria,1RJZ7@1224|Proteobacteria 1224|Proteobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - TGS3_k127_1799484_1 314278.NB231_08395 6.819e-54 202.0 COG0457@1|root,COG0457@2|Bacteria,1NEP9@1224|Proteobacteria,1T3U4@1236|Gammaproteobacteria,1X17I@135613|Chromatiales 135613|Chromatiales S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3 TGS3_k127_1799484_0 1161401.ASJA01000001_gene532 1.298e-97 327.0 COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2TS2D@28211|Alphaproteobacteria,43XHY@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC - 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase TGS3_k127_1799484_3 394221.Mmar10_1720 4.216e-13 79.0 COG3147@1|root,COG3147@2|Bacteria,1QZWI@1224|Proteobacteria,2UKVR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Sporulation related domain - - - - - - - - - - - - SPOR TGS3_k127_1799484_4 1117315.AHCA01000011_gene1384 6.312e-12 75.0 COG3121@1|root,COG3121@2|Bacteria,1RFSJ@1224|Proteobacteria,1S3QQ@1236|Gammaproteobacteria,2Q2IJ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria NU Pili and flagellar-assembly chaperone, PapD N-terminal domain - - - - - - - - - - - - PapD_N TGS3_k127_1837383_0 1280952.HJA_03066 1.074e-203 645.0 COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2TQP6@28211|Alphaproteobacteria,43WER@69657|Hyphomonadaceae 28211|Alphaproteobacteria S protein related to deoxyribodipyrimidine photolyase phrB GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003913,GO:0003914,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - ko:K06876 - - - - ko00000 - - - DPRP,FAD_binding_7 TGS3_k127_1837383_1 1336235.JAEG01000015_gene4496 1.546e-64 228.0 COG1028@1|root,COG1028@2|Bacteria,1RAEZ@1224|Proteobacteria,2U7DM@28211|Alphaproteobacteria,4B9Z9@82115|Rhizobiaceae 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase csgA - - - - - - - - - - - adh_short,adh_short_C2 TGS3_k127_1837383_2 96561.Dole_3252 2.703e-05 46.0 COG4719@1|root,COG4719@2|Bacteria,1N09K@1224|Proteobacteria,42UTG@68525|delta/epsilon subdivisions,2WQR7@28221|Deltaproteobacteria,2MP1P@213118|Desulfobacterales 28221|Deltaproteobacteria S TIGRFAM conserved repeat domain - - - - - - - - - - - - DUF11 TGS3_k127_1846378_1 1545915.JROG01000003_gene625 6.627e-58 206.0 COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,2TVY6@28211|Alphaproteobacteria,2K3HZ@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short TGS3_k127_1846378_0 394221.Mmar10_0124 3.891e-145 471.0 COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,2TUM5@28211|Alphaproteobacteria,43W54@69657|Hyphomonadaceae 28211|Alphaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - ko:K08225 - - - - ko00000,ko02000 2.A.1.38 - - MFS_1,MFS_3 TGS3_k127_1861264_14 1247963.JPHU01000005_gene298 5.552e-17 83.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TSX9@28211|Alphaproteobacteria 28211|Alphaproteobacteria BQ Including yeast histone deacetylase and acetoin utilization protein acuC - - ko:K04768 - - - - ko00000 - - - Hist_deacetyl TGS3_k127_1861264_2 1122137.AQXF01000001_gene3380 1.201e-139 459.0 COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,2TUHT@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - ko:K13049 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 TGS3_k127_1861264_13 1280953.HOC_17080 5.531e-32 126.0 2AYJR@1|root,31QPU@2|Bacteria,1QN9N@1224|Proteobacteria,2V944@28211|Alphaproteobacteria,4407B@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_1861264_1 876044.IMCC3088_473 2.531e-151 484.0 COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,1RTQR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S 2-nitropropane dioxygenase - - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO TGS3_k127_1861264_0 317655.Sala_0537 3.191e-230 724.0 COG2978@1|root,COG2978@2|Bacteria,1MUJ1@1224|Proteobacteria,2U1AP@28211|Alphaproteobacteria,2K8GQ@204457|Sphingomonadales 204457|Sphingomonadales H AbgT putative transporter family - - - ko:K12942 - - - - ko00000 - - - ABG_transport TGS3_k127_1861264_4 384765.SIAM614_15782 1.152e-74 255.0 COG1309@1|root,COG1309@2|Bacteria,1R7YG@1224|Proteobacteria,2U3ZJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator - - - ko:K16137 - - - - ko00000,ko03000 - - - TetR_N TGS3_k127_1861264_7 582402.Hbal_0181 3.266e-56 203.0 COG3832@1|root,COG3832@2|Bacteria,1RD0P@1224|Proteobacteria,2U79U@28211|Alphaproteobacteria,43YCY@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 TGS3_k127_1861264_8 187303.BN69_2756 7.561e-55 197.0 COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,2UBGF@28211|Alphaproteobacteria,371FE@31993|Methylocystaceae 28211|Alphaproteobacteria S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase TGS3_k127_1861264_10 326424.FRAAL2365 3.722e-49 180.0 COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria,4ESIH@85013|Frankiales 201174|Actinobacteria S 3-demethylubiquinone-9 3-methyltransferase - - - - - - - - - - - - 3-dmu-9_3-mt TGS3_k127_1861264_11 388051.AUFE01000005_gene1131 4.271e-44 163.0 COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,2VSZQ@28216|Betaproteobacteria,1K7UH@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF1428) ybaA - - - - - - - - - - - DUF1428 TGS3_k127_1861264_9 224911.27351211 8.182e-53 191.0 COG3304@1|root,COG3304@2|Bacteria,1RA96@1224|Proteobacteria,2U742@28211|Alphaproteobacteria,3JYSW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Inner membrane component domain MA20_16325 - - - - - - - - - - - YccF TGS3_k127_1861264_5 1267534.KB906759_gene1769 9.08e-68 242.0 COG0491@1|root,COG0491@2|Bacteria 2|Bacteria GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - - - - - - - - - - Lactamase_B TGS3_k127_1861264_6 551275.KB899546_gene2319 3.545e-65 230.0 COG3738@1|root,COG3738@2|Bacteria,1RE1M@1224|Proteobacteria,2U9JW@28211|Alphaproteobacteria,43XXQ@69657|Hyphomonadaceae 28211|Alphaproteobacteria S protein conserved in bacteria - - - ko:K09974 - - - - ko00000 - - - DUF1287 TGS3_k127_1861264_3 1268072.PSAB_18425 1.099e-107 359.0 COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,26S2B@186822|Paenibacillaceae 91061|Bacilli C aldo keto reductase - - - - - - - - - - - - Aldo_ket_red TGS3_k127_1861264_12 190650.CC_2205 4.26e-38 146.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2TR2V@28211|Alphaproteobacteria,2KF9H@204458|Caulobacterales 204458|Caulobacterales J Belongs to the class-I aminoacyl-tRNA synthetase family - - - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c TGS3_k127_1911868_0 176299.Atu2759 1.452e-225 706.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2TR48@28211|Alphaproteobacteria,4B9EM@82115|Rhizobiaceae 28211|Alphaproteobacteria D DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma TGS3_k127_1911868_4 1101190.ARWB01000001_gene2610 3.225e-15 82.0 COG5573@1|root,COG5573@2|Bacteria,1RKHC@1224|Proteobacteria,2UHIW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S nucleic-acid-binding protein contains PIN domain - - - - - - - - - - - - PIN TGS3_k127_1911868_3 1122970.AUHC01000005_gene1899 1.22e-68 249.0 COG5653@1|root,COG5653@2|Bacteria,1N3Z9@1224|Proteobacteria,2TRT5@28211|Alphaproteobacteria,2K1RW@204457|Sphingomonadales 204457|Sphingomonadales M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 TGS3_k127_1911868_2 1219035.NT2_12_00360 6.644e-76 264.0 COG2850@1|root,COG2850@2|Bacteria,1MXD0@1224|Proteobacteria,2U0CY@28211|Alphaproteobacteria,2K1HD@204457|Sphingomonadales 204457|Sphingomonadales S A domain family that is part of the cupin metalloenzyme superfamily. - - - - - - - - - - - - Cupin_8 TGS3_k127_1911868_1 1238182.C882_1709 4.636e-200 634.0 COG0775@1|root,COG0775@2|Bacteria,1MUMQ@1224|Proteobacteria,2TSX1@28211|Alphaproteobacteria,2JRAC@204441|Rhodospirillales 204441|Rhodospirillales F Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations amn - 3.2.2.4 ko:K01241 ko00230,map00230 - R00182 RC00063,RC00318 ko00000,ko00001,ko01000 - - - AMNp_N,PNP_UDP_1 TGS3_k127_1911868_5 1187851.A33M_3880 1.659e-13 74.0 COG1669@1|root,COG1669@2|Bacteria,1NEHM@1224|Proteobacteria,2UG94@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM DNA polymerase, beta domain protein region - - - ko:K07075 - - - - ko00000 - - - NTP_transf_2 TGS3_k127_1911868_6 1267535.KB906767_gene759 1.82e-10 67.0 COG2361@1|root,COG2361@2|Bacteria,3Y5UP@57723|Acidobacteria,2JK4F@204432|Acidobacteriia 204432|Acidobacteriia S Protein of unknown function DUF86 - - - - - - - - - - - - DUF86 TGS3_k127_1927039_2 1247963.JPHU01000001_gene1824 3.185e-69 246.0 COG0697@1|root,COG0697@2|Bacteria,1MVKG@1224|Proteobacteria,2U30N@28211|Alphaproteobacteria 28211|Alphaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - ko:K15268 - - - - ko00000,ko02000 2.A.7.3.2 - - EamA TGS3_k127_1927039_1 1247963.JPHU01000001_gene1823 9.641e-71 260.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2TSW3@28211|Alphaproteobacteria 28211|Alphaproteobacteria V N-acetylmuramoyl-L-alanine amidase ampD - 3.5.1.28 ko:K01447,ko:K03806,ko:K11066 - - R04112 RC00064,RC00141 ko00000,ko01000,ko01011 - - - Amidase_2,PG_binding_1 TGS3_k127_1927039_9 999141.GME_04962 3.026e-12 70.0 COG3609@1|root,COG3609@2|Bacteria,1N9NJ@1224|Proteobacteria,1S9Z4@1236|Gammaproteobacteria,1XMNS@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - - - - - - - - - - ParD_antitoxin TGS3_k127_1927039_8 710687.KI912270_gene5134 3.414e-15 79.0 COG3668@1|root,COG3668@2|Bacteria,2IRP1@201174|Actinobacteria,23AW5@1762|Mycobacteriaceae 201174|Actinobacteria S Belongs to the RelE toxin family parE1 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - ko:K19092 - - - - ko00000,ko02048 - - - ParE_toxin TGS3_k127_1927039_5 1033802.SSPSH_001132 1.094e-42 160.0 COG0824@1|root,COG0824@2|Bacteria,1RI3X@1224|Proteobacteria,1SAHQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Thioesterase - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2,Acyl-ACP_TE TGS3_k127_1927039_3 1282876.BAOK01000001_gene1130 3.253e-67 231.0 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,2U7GR@28211|Alphaproteobacteria,4BQGP@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the UPF0234 family - - - ko:K09767 - - - - ko00000 - - - DUF520 TGS3_k127_1927039_10 670307.HYPDE_31008 5.829e-11 66.0 COG0236@1|root,COG0236@2|Bacteria,1NHZ9@1224|Proteobacteria,2UK27@28211|Alphaproteobacteria,3N8Y5@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria IQ Phosphopantetheine attachment site nodF - - ko:K02078,ko:K14661 - - - - ko00000,ko00001,ko01000 - - - PP-binding TGS3_k127_1927039_0 666685.R2APBS1_1088 5.77e-117 388.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1X3GS@135614|Xanthomonadales 135614|Xanthomonadales IQ Belongs to the beta-ketoacyl-ACP synthases family - - - ko:K14660 - - - - ko00000,ko01000 - - - Ketoacyl-synt_C,ketoacyl-synt TGS3_k127_1927039_4 158500.BV97_04045 5.169e-43 164.0 COG5592@1|root,COG5592@2|Bacteria,1RI8J@1224|Proteobacteria,2U7JS@28211|Alphaproteobacteria,2K402@204457|Sphingomonadales 204457|Sphingomonadales S Hemerythrin - - - - - - - - - - - - Hemerythrin TGS3_k127_1927039_6 1231190.NA8A_06048 2.129e-35 137.0 COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2TQRE@28211|Alphaproteobacteria,43HQI@69277|Phyllobacteriaceae 28211|Alphaproteobacteria T Histidine kinase envZ - 2.7.13.3 ko:K07638 ko02020,ko02026,map02020,map02026 M00445,M00742,M00743 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA TGS3_k127_1929543_2 1247963.JPHU01000010_gene2258 1.799e-26 112.0 COG1426@1|root,COG1426@2|Bacteria,1NBD0@1224|Proteobacteria,2UGGH@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Helix-turn-helix - - - - - - - - - - - - HTH_3,HTH_31 TGS3_k127_1929543_4 491916.RHECIAT_CH0002943 1.862e-07 54.0 2A9UM@1|root,30Z2G@2|Bacteria,1PQIA@1224|Proteobacteria,2V2X8@28211|Alphaproteobacteria,4BJT2@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_1929543_1 1247963.JPHU01000003_gene1232 1.121e-40 158.0 COG3814@1|root,COG3814@2|Bacteria,1N1FE@1224|Proteobacteria,2U7H9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria MA20_02250 - - ko:K09985 - - - - ko00000 - - - SspB TGS3_k127_1929543_0 1502724.FF80_04083 2.853e-78 280.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2TTX6@28211|Alphaproteobacteria,3N7H4@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S RmuC family rmuC - - ko:K09760 - - - - ko00000 - - - RmuC TGS3_k127_1929543_3 1211114.ALIP01000022_gene2424 3.311e-21 95.0 COG1476@1|root,COG1476@2|Bacteria,1N6SS@1224|Proteobacteria,1SCB0@1236|Gammaproteobacteria,1XD0A@135614|Xanthomonadales 135614|Xanthomonadales K Helix-turn-helix domain - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 TGS3_k127_1935596_8 517722.AEUE01000007_gene265 1.253e-75 262.0 COG0584@1|root,COG0584@2|Bacteria,1MYB7@1224|Proteobacteria,2UA5S@28211|Alphaproteobacteria,2K8DA@204457|Sphingomonadales 204457|Sphingomonadales C Glycerophosphoryl diester phosphodiesterase family - - - - - - - - - - - - GDPD TGS3_k127_1935596_6 1415780.JPOG01000001_gene2445 6.47e-81 286.0 COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,1RPCQ@1236|Gammaproteobacteria,1X5WS@135614|Xanthomonadales 135614|Xanthomonadales C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N TGS3_k127_1935596_13 314260.PB2503_04422 1.761e-15 85.0 2EMU4@1|root,33FGG@2|Bacteria,1NNB6@1224|Proteobacteria,2UMJV@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_1935596_2 1449049.JONW01000006_gene2584 2.176e-111 379.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2TQZW@28211|Alphaproteobacteria,2KFRG@204458|Caulobacterales 204458|Caulobacterales J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N TGS3_k127_1935596_0 414684.RC1_2810 3.225e-258 809.0 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2TRJS@28211|Alphaproteobacteria,2JRDM@204441|Rhodospirillales 204441|Rhodospirillales D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA - - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc TGS3_k127_1935596_10 414684.RC1_2811 4.535e-45 171.0 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2U9T9@28211|Alphaproteobacteria,2JS6N@204441|Rhodospirillales 204441|Rhodospirillales J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG - 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB TGS3_k127_1935596_1 1247963.JPHU01000002_gene2726 4.347e-112 367.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2TSWH@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Chromosome Partitioning parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 TGS3_k127_1935596_5 246200.SPO0004 4.529e-85 292.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,4NBRG@97050|Ruegeria 28211|Alphaproteobacteria K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc TGS3_k127_1935596_3 1247963.JPHU01000002_gene2672 6.218e-111 362.0 COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,2TR97@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain mtrA - - - - - - - - - - - Response_reg,Trans_reg_C TGS3_k127_1935596_7 1110502.TMO_3429 3.662e-78 267.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2TR5Z@28211|Alphaproteobacteria,2JQKQ@204441|Rhodospirillales 204441|Rhodospirillales S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis - - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N TGS3_k127_1935596_12 1238182.C882_3248 1.396e-28 124.0 COG0352@1|root,COG0352@2|Bacteria,1MZ0K@1224|Proteobacteria,2UA7U@28211|Alphaproteobacteria,2JT3I@204441|Rhodospirillales 204441|Rhodospirillales H Thiamine monophosphate synthase - - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI TGS3_k127_1935596_9 1121377.KB906418_gene3787 5.343e-48 183.0 COG5640@1|root,COG5640@2|Bacteria,1WN2M@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O Trypsin-like serine protease - - - - - - - - - - - - Trypsin TGS3_k127_1935596_4 1247963.JPHU01000002_gene2704 4.964e-87 300.0 COG1466@1|root,COG1466@2|Bacteria,1R8PA@1224|Proteobacteria,2U1KQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta TGS3_k127_1935596_14 1247963.JPHU01000002_gene2705 1.424e-12 74.0 COG5468@1|root,COG5468@2|Bacteria 2|Bacteria S Lipopolysaccharide-assembly - - - ko:K03643 - - - - ko00000,ko02000 1.B.42.1 - - LptE TGS3_k127_1935596_11 1247963.JPHU01000002_gene2706 2.642e-38 148.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2TQPK@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 TGS3_k127_1953670_2 1054213.HMPREF9946_01417 1.17e-77 260.0 COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,2TSJR@28211|Alphaproteobacteria,2JQAS@204441|Rhodospirillales 204441|Rhodospirillales E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N TGS3_k127_1953670_1 1123267.JONN01000001_gene2292 1.705e-187 598.0 COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,2TSPJ@28211|Alphaproteobacteria,2K1IZ@204457|Sphingomonadales 204457|Sphingomonadales E Histidine hutH - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic TGS3_k127_1953670_0 1247963.JPHU01000003_gene1309 6.838e-273 862.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2TRCK@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0339 Zn-dependent oligopeptidases dcp GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.15.5 ko:K01284 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 TGS3_k127_1983173_2 313612.L8106_04811 6.186e-73 266.0 COG2931@1|root,COG3291@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria,1G3EW@1117|Cyanobacteria,1HBBU@1150|Oscillatoriales 1117|Cyanobacteria Q G8 - - - - - - - - - - - - G8,HemolysinCabind,Laminin_G_3,PKD TGS3_k127_1983173_5 1247963.JPHU01000005_gene395 2.337e-48 181.0 COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,2TTN7@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran TGS3_k127_1983173_8 1247963.JPHU01000005_gene396 4.371e-13 81.0 2E521@1|root,32ZVA@2|Bacteria,1NH3G@1224|Proteobacteria,2UKE1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S zinc-ribbon domain - - - - - - - - - - - - DUF3426,zinc_ribbon_4 TGS3_k127_1983173_10 419610.Mext_2862 6.834e-09 68.0 2E521@1|root,32ZVA@2|Bacteria,1N9PP@1224|Proteobacteria,2UG1E@28211|Alphaproteobacteria,1JTNR@119045|Methylobacteriaceae 28211|Alphaproteobacteria S TIGRFAM MJ0042 family finger-like protein - - - - - - - - - - - - DUF3426,zinc_ribbon_4 TGS3_k127_1983173_1 1247963.JPHU01000005_gene397 1.167e-95 321.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2TS9Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria D cell division ATP-binding protein FtsE ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran TGS3_k127_1983173_3 1247963.JPHU01000005_gene398 2.418e-57 213.0 COG2177@1|root,COG2177@2|Bacteria,1MXKQ@1224|Proteobacteria,2TSNT@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Cell division protein ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - - TGS3_k127_1983173_7 1121124.JNIX01000013_gene1570 1.043e-40 158.0 COG1434@1|root,COG1434@2|Bacteria,1RHMV@1224|Proteobacteria,2U957@28211|Alphaproteobacteria,2KGI6@204458|Caulobacterales 204458|Caulobacterales S DUF218 domain - - - - - - - - - - - - DUF218 TGS3_k127_1983173_4 1123503.KB908057_gene2669 1.792e-52 195.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2TT3P@28211|Alphaproteobacteria,2KGAR@204458|Caulobacterales 204458|Caulobacterales I Acyltransferase - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase TGS3_k127_1983173_9 314260.PB2503_02797 1.04e-10 72.0 COG0204@1|root,COG4093@1|root,COG0204@2|Bacteria,COG4093@2|Bacteria,1MY51@1224|Proteobacteria,2TT3P@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Acyl-transferase plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase TGS3_k127_1983173_6 1247963.JPHU01000011_gene730 1.983e-42 159.0 COG1846@1|root,COG1846@2|Bacteria,1NE6J@1224|Proteobacteria,2UFK7@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional - - - - - - - - - - - - MarR,MarR_2 TGS3_k127_1983173_0 224914.BMEI1948 1.621e-145 474.0 COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,2TSI6@28211|Alphaproteobacteria,1J2GM@118882|Brucellaceae 28211|Alphaproteobacteria E Cytosol aminopeptidase family, catalytic domain pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17 TGS3_k127_1984764_2 1280947.HY30_09740 7.513e-37 151.0 COG2017@1|root,COG2017@2|Bacteria,1RGXX@1224|Proteobacteria,2UDRM@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG2017 Galactose mutarotase and related enzymes - - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim TGS3_k127_1984764_0 1547437.LL06_06580 8.495e-134 431.0 COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,2TSSU@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 TGS3_k127_1984764_1 402881.Plav_1436 1.865e-123 403.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2TQYF@28211|Alphaproteobacteria,1JNIJ@119043|Rhodobiaceae 28211|Alphaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_10,Fer4_17,Fer4_8 TGS3_k127_1989125_2 1121949.AQXT01000002_gene2248 4.245e-137 446.0 COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,2TRYD@28211|Alphaproteobacteria,43WN0@69657|Hyphomonadaceae 28211|Alphaproteobacteria J 2-methylthioadenine mtaB GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,UPF0004 TGS3_k127_1989125_8 1122137.AQXF01000006_gene859 2.114e-65 237.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2TR76@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Permease, YjgP YjgQ family - - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ TGS3_k127_1989125_7 745310.G432_06160 9.44e-75 267.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2U55Q@28211|Alphaproteobacteria,2K07C@204457|Sphingomonadales 204457|Sphingomonadales S YjgP YjgQ family - - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ TGS3_k127_1989125_11 1122137.AQXF01000004_gene1705 5.95e-46 179.0 2EDGC@1|root,337CJ@2|Bacteria,1N6E3@1224|Proteobacteria,2UCX7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_1989125_9 629773.AORY01000014_gene2527 2.274e-65 232.0 COG1215@1|root,COG1215@2|Bacteria,1R6C4@1224|Proteobacteria,2UAG0@28211|Alphaproteobacteria,2K0HN@204457|Sphingomonadales 204457|Sphingomonadales M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 TGS3_k127_1989125_5 190650.CC_0755 1.329e-102 346.0 COG0438@1|root,COG0438@2|Bacteria,1NU0D@1224|Proteobacteria,2U2M4@28211|Alphaproteobacteria,2KJRY@204458|Caulobacterales 204458|Caulobacterales M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_transf_4 TGS3_k127_1989125_3 1122137.AQXF01000004_gene1706 1.569e-114 381.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2TQQ0@28211|Alphaproteobacteria 28211|Alphaproteobacteria M glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 TGS3_k127_1989125_1 1188256.BASI01000001_gene587 1.513e-151 491.0 COG0661@1|root,COG0661@2|Bacteria,1MW1J@1224|Proteobacteria,2TSHG@28211|Alphaproteobacteria,3FDJG@34008|Rhodovulum 28211|Alphaproteobacteria S ABC1 family - - - - - - - - - - - - ABC1 TGS3_k127_1989125_12 1280949.HAD_15442 5.54e-42 163.0 COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,2U33F@28211|Alphaproteobacteria,43YFA@69657|Hyphomonadaceae 28211|Alphaproteobacteria S secreted protein - - - - - - - - - - - - DUF1223 TGS3_k127_1989125_0 1161401.ASJA01000001_gene278 2.559e-273 856.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TQWP@28211|Alphaproteobacteria,43X65@69657|Hyphomonadaceae 28211|Alphaproteobacteria M COG0405 Gamma-glutamyltransferase ggt1 - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept TGS3_k127_1989125_10 1121949.AQXT01000002_gene1111 6.56e-64 225.0 COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,2U5TA@28211|Alphaproteobacteria,43XJZ@69657|Hyphomonadaceae 28211|Alphaproteobacteria I COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - - - - - - - - - - Acyltransferase TGS3_k127_1989125_6 420324.KI912027_gene320 3.01e-78 269.0 COG1708@1|root,COG1708@2|Bacteria,1R03C@1224|Proteobacteria,2TUZ0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S nucleotidyltransferase activity - - - - - - - - - - - - - TGS3_k127_1989125_4 882086.SacxiDRAFT_3798 1.81e-108 359.0 COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria,4DZEJ@85010|Pseudonocardiales 201174|Actinobacteria S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 TGS3_k127_1989125_13 566466.NOR53_491 3.887e-28 116.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Adenylate cyclase - - - - - - - - - - - - TPR_11,TPR_16,TPR_19,TPR_2,TPR_8,Trans_reg_C TGS3_k127_199946_0 1247963.JPHU01000001_gene2027 0.0 1032.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2TQZU@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS TGS3_k127_2012680_0 1449049.JONW01000005_gene1013 4.958e-251 800.0 COG1629@1|root,COG1629@2|Bacteria,1QUTW@1224|Proteobacteria,2TW7F@28211|Alphaproteobacteria,2KFR5@204458|Caulobacterales 204458|Caulobacterales P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec TGS3_k127_2012680_1 392499.Swit_2115 2.892e-117 386.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2U0BD@28211|Alphaproteobacteria,2KCU9@204457|Sphingomonadales 204457|Sphingomonadales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 TGS3_k127_2019905_8 314260.PB2503_09639 2.361e-10 63.0 COG0483@1|root,COG0483@2|Bacteria,1NFR1@1224|Proteobacteria,2U1X2@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Inositol monophosphatase - - - - - - - - - - - - Inositol_P TGS3_k127_2019905_3 1121948.AUAC01000002_gene1131 4.544e-96 322.0 COG4221@1|root,COG4221@2|Bacteria,1QTXD@1224|Proteobacteria,2TW4Q@28211|Alphaproteobacteria,43YCX@69657|Hyphomonadaceae 28211|Alphaproteobacteria S KR domain - - - - - - - - - - - - adh_short TGS3_k127_2019905_4 402881.Plav_3121 1.151e-94 319.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,1JNNB@119043|Rhodobiaceae 28211|Alphaproteobacteria S MazG nucleotide pyrophosphohydrolase domain mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 ko:K02499,ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG TGS3_k127_2019905_2 314260.PB2503_09664 4.033e-121 398.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TR1H@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 TGS3_k127_2019905_7 1333998.M2A_0214 7.481e-26 113.0 COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,2UF72@28211|Alphaproteobacteria,4BQYH@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Protein affecting phage T7 exclusion by the F plasmid fxsA - - ko:K07113 - - - - ko00000 - - - FxsA TGS3_k127_2019905_1 1283300.ATXB01000001_gene1937 3.707e-161 523.0 COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,1RNG8@1236|Gammaproteobacteria,1XE21@135618|Methylococcales 135618|Methylococcales P Belongs to the alkaline phosphatase family - - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase TGS3_k127_2019905_0 1333998.M2A_1662 8.189e-214 686.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2TS4D@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG2366 Protein related to penicillin acylase - - 3.5.1.11,3.5.1.97 ko:K01434,ko:K07116 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase TGS3_k127_2019905_5 685778.AORL01000015_gene2451 8.792e-83 280.0 COG0625@1|root,COG0625@2|Bacteria,1PENB@1224|Proteobacteria,2TRVC@28211|Alphaproteobacteria,2K49C@204457|Sphingomonadales 204457|Sphingomonadales O Glutathione S-transferase, N-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N_3 TGS3_k127_2019905_9 1247963.JPHU01000005_gene341 6.772e-06 52.0 COG2214@1|root,COG2214@2|Bacteria,1PA8G@1224|Proteobacteria,2UWQC@28211|Alphaproteobacteria 28211|Alphaproteobacteria O DnaJ molecular chaperone homology domain - - - - - - - - - - - - - TGS3_k127_2019905_6 59538.XP_005968316.1 1.891e-30 121.0 COG1235@1|root,2QWBK@2759|Eukaryota,39ZXT@33154|Opisthokonta 33154|Opisthokonta S Beta-lactamase superfamily domain - GO:0003674,GO:0003824,GO:0016787 - - - - - - - - - - Lactamase_B_2 TGS3_k127_2027120_0 1380394.JADL01000008_gene3671 1.091e-113 381.0 COG0438@1|root,COG0438@2|Bacteria,1R564@1224|Proteobacteria,2TTA7@28211|Alphaproteobacteria,2JPDS@204441|Rhodospirillales 204441|Rhodospirillales M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 TGS3_k127_2027120_1 1408428.JNJP01000024_gene3738 2.464e-65 232.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42NH8@68525|delta/epsilon subdivisions,2WJMA@28221|Deltaproteobacteria,2MA09@213115|Desulfovibrionales 28221|Deltaproteobacteria M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - - - - - - - - - - Bac_transf,CoA_binding_3 TGS3_k127_2034313_0 1247963.JPHU01000003_gene1473 5.592e-113 374.0 COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,2TQKZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria N flagellar motor protein MA20_18060 - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - OmpA TGS3_k127_2034313_2 314260.PB2503_01677 5.177e-76 289.0 COG1511@1|root,COG1511@2|Bacteria,1NYJB@1224|Proteobacteria,2TSX0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S MotA TolQ ExbB proton channel family MA20_18055 - - - - - - - - - - - MotA_ExbB TGS3_k127_2034313_1 1161401.ASJA01000023_gene154 1.914e-90 309.0 COG4247@1|root,COG4247@2|Bacteria,1MVTA@1224|Proteobacteria,2TUDJ@28211|Alphaproteobacteria,43WCU@69657|Hyphomonadaceae 28211|Alphaproteobacteria I COG4247 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) phy - 3.1.3.8 ko:K01083 ko00562,map00562 - R03371 RC00078 ko00000,ko00001,ko01000 - - - Phytase TGS3_k127_2034313_3 1188256.BASI01000002_gene3699 1.54e-72 247.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2TR63@28211|Alphaproteobacteria,3FCI1@34008|Rhodovulum 28211|Alphaproteobacteria T Elongation factor G C-terminus typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 TGS3_k127_2049533_2 472175.EL18_02373 1.824e-30 124.0 COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2UC42@28211|Alphaproteobacteria,43KPC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p TGS3_k127_2049533_0 864069.MicloDRAFT_00015560 2.991e-98 329.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria,1JSW8@119045|Methylobacteriaceae 28211|Alphaproteobacteria L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS TGS3_k127_2049533_1 366602.Caul_3400 3.515e-60 222.0 COG4269@1|root,COG4269@2|Bacteria,1MW5P@1224|Proteobacteria,2U0EV@28211|Alphaproteobacteria,2KHMU@204458|Caulobacterales 204458|Caulobacterales S Bacterial protein of unknown function (DUF898) - - - - - - - - - - - - DUF898 TGS3_k127_2049533_3 1121123.AUAO01000003_gene2533 2.988e-11 76.0 COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,2TREZ@28211|Alphaproteobacteria,2KI5G@204458|Caulobacterales 204458|Caulobacterales O Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 TGS3_k127_2054530_3 270374.MELB17_05087 2.443e-51 188.0 COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,1S846@1236|Gammaproteobacteria,467UD@72275|Alteromonadaceae 1236|Gammaproteobacteria S YHS domain - - - - - - - - - - - - YHS TGS3_k127_2054530_1 1242864.D187_003608 1.426e-67 255.0 COG2367@1|root,COG2367@2|Bacteria 2|Bacteria V Beta-lactamase - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 TGS3_k127_2054530_2 243090.RB2098 8.921e-60 231.0 COG1680@1|root,COG3653@1|root,COG1680@2|Bacteria,COG3653@2|Bacteria,2IY88@203682|Planctomycetes 203682|Planctomycetes V Beta-lactamase class C - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Beta-lactamase TGS3_k127_2054530_7 1122134.KB893650_gene534 7.826e-18 89.0 2ES46@1|root,33JP4@2|Bacteria,1NP0N@1224|Proteobacteria,1SRKK@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_2054530_0 314260.PB2503_01942 0.0 1093.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2TQSP@28211|Alphaproteobacteria 28211|Alphaproteobacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB TGS3_k127_2054530_4 95619.PM1_0206035 5.601e-43 160.0 COG4683@1|root,COG4683@2|Bacteria,1MZIY@1224|Proteobacteria,1S686@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria VY92_07350 - - - - - - - - - - - Gp49 TGS3_k127_2054530_5 56107.Cylst_4903 8.463e-26 111.0 COG1396@1|root,COG1396@2|Bacteria,1G9VE@1117|Cyanobacteria,1HPNX@1161|Nostocales 1117|Cyanobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_37 TGS3_k127_2054530_8 1123504.JQKD01000012_gene1238 1.119e-12 74.0 COG1848@1|root,COG1848@2|Bacteria,1RK9K@1224|Proteobacteria 1224|Proteobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - ko:K07064 - - - - ko00000 - - - PIN TGS3_k127_2054530_6 228405.HNE_2108 6.893e-19 89.0 COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,2U2G6@28211|Alphaproteobacteria 28211|Alphaproteobacteria L transposase IS116 IS110 IS902 family protein - - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 TGS3_k127_206570_5 1247963.JPHU01000011_gene819 2.812e-39 155.0 COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2TRS4@28211|Alphaproteobacteria 28211|Alphaproteobacteria M glycosyl transferase, family 39 - - - - - - - - - - - - PMT,PMT_2 TGS3_k127_206570_2 314260.PB2503_07749 1.469e-101 349.0 COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,2TV39@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 TGS3_k127_206570_3 1247963.JPHU01000015_gene1118 7.332e-83 285.0 COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,2TRZB@28211|Alphaproteobacteria 28211|Alphaproteobacteria M glycosyl transferase - - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glycos_transf_2 TGS3_k127_206570_7 1247963.JPHU01000003_gene1410 2.579e-30 135.0 COG3307@1|root,COG3307@2|Bacteria,1NBBK@1224|Proteobacteria,2UJ3M@28211|Alphaproteobacteria 28211|Alphaproteobacteria M O-Antigen ligase - - - - - - - - - - - - Wzy_C TGS3_k127_206570_0 1333998.M2A_2522 2.076e-303 945.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2TQWI@28211|Alphaproteobacteria,4BPFD@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD TGS3_k127_206570_8 1280941.HY2_11335 1.44e-25 109.0 COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2UFKH@28211|Alphaproteobacteria,43YJC@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Could be involved in insertion of integral membrane proteins into the membrane yidD - - ko:K08998 - - - - ko00000 - - - Haemolytic TGS3_k127_206570_1 1161401.ASJA01000006_gene1942 6.265e-125 413.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,43X0S@69657|Hyphomonadaceae 28211|Alphaproteobacteria E COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 TGS3_k127_206570_6 331869.BAL199_18691 3.375e-36 139.0 COG1917@1|root,COG1917@2|Bacteria,1QUA5@1224|Proteobacteria,2UC97@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 TGS3_k127_206570_4 402881.Plav_0598 2.461e-64 224.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2TSTH@28211|Alphaproteobacteria,1JNJT@119043|Rhodobiaceae 28211|Alphaproteobacteria J Anticodon binding domain hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His TGS3_k127_2081912_2 192952.MM_2219 3.728e-29 130.0 COG0500@1|root,arCOG01789@2157|Archaea,2Y3U4@28890|Euryarchaeota,2NAUS@224756|Methanomicrobia 224756|Methanomicrobia Q Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_11 TGS3_k127_2081912_1 479434.Sthe_0859 3.294e-101 342.0 COG0463@1|root,COG0463@2|Bacteria,2G5X5@200795|Chloroflexi,27XQE@189775|Thermomicrobia 189775|Thermomicrobia M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 TGS3_k127_2081912_0 228405.HNE_2108 1.839e-101 339.0 COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,2U2G6@28211|Alphaproteobacteria 28211|Alphaproteobacteria L transposase IS116 IS110 IS902 family protein - - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 TGS3_k127_2110680_3 1122137.AQXF01000003_gene1870 1.01e-59 211.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran TGS3_k127_2110680_4 1122137.AQXF01000003_gene1871 1.564e-59 221.0 COG0845@1|root,COG0845@2|Bacteria,1MV1T@1224|Proteobacteria,2VFH0@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - HlyD_D23 TGS3_k127_2110680_7 698761.RTCIAT899_CH00180 3.506e-22 101.0 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2UC0H@28211|Alphaproteobacteria,4BGAS@82115|Rhizobiaceae 28211|Alphaproteobacteria G Phosphotransferase System ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006808,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0044424,GO:0044464,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr TGS3_k127_2110680_5 450851.PHZ_c0086 7.201e-54 192.0 COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2U9E5@28211|Alphaproteobacteria,2KGF3@204458|Caulobacterales 204458|Caulobacterales G PFAM PTS system fructose subfamily IIA component - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man TGS3_k127_2110680_8 314260.PB2503_03992 1.127e-11 72.0 COG1493@1|root,COG1493@2|Bacteria 2|Bacteria T Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N TGS3_k127_2110680_0 1247963.JPHU01000011_gene722 6.383e-190 611.0 COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1N17V@1224|Proteobacteria,2TS69@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase chvG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K14980 ko02020,map02020 M00520 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,Sensor_TM1,Stimulus_sens_1 TGS3_k127_2110680_2 1247963.JPHU01000011_gene723 4.793e-113 368.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2TR43@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain chvI GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K14981 ko02020,map02020 M00520 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C TGS3_k127_2110680_6 555793.WSK_1648 1.09e-31 126.0 COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2UBWN@28211|Alphaproteobacteria,2K5VW@204457|Sphingomonadales 204457|Sphingomonadales H pterin-4-alpha-carbinolamine dehydratase - - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a TGS3_k127_2110680_1 1382303.JPOM01000001_gene140 3.469e-180 576.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TRNX@28211|Alphaproteobacteria,2KG4Y@204458|Caulobacterales 204458|Caulobacterales E amino acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 TGS3_k127_2111850_0 314260.PB2503_02617 1.303e-125 407.0 COG1257@1|root,COG1257@2|Bacteria,1Q6M1@1224|Proteobacteria,2U1F3@28211|Alphaproteobacteria 28211|Alphaproteobacteria I COG1257 Hydroxymethylglutaryl-CoA reductase - - 1.1.1.34 ko:K00021 ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976 M00095 R02082 RC00004,RC00644 ko00000,ko00001,ko00002,ko01000 - - - HMG-CoA_red TGS3_k127_2111850_1 1036674.A28LD_0882 3.396e-97 330.0 COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,1RQ0T@1236|Gammaproteobacteria,2QFQR@267893|Idiomarinaceae 1236|Gammaproteobacteria C Belongs to the Glu Leu Phe Val dehydrogenases family ldh - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N TGS3_k127_2111850_2 1247963.JPHU01000012_gene861 1.101e-65 228.0 COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2VG6J@28211|Alphaproteobacteria 28211|Alphaproteobacteria K helix_turn_helix ASNC type - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24 TGS3_k127_214021_0 1042377.AFPJ01000009_gene289 0.0 1049.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMXI@1236|Gammaproteobacteria,464BP@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M3 dcp - 3.4.15.5 ko:K01284 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 TGS3_k127_214021_2 1254432.SCE1572_43615 1.57e-37 145.0 COG5611@1|root,COG5611@2|Bacteria 2|Bacteria S PIN domain vapC - - - - - - - - - - - PIN TGS3_k127_214021_1 1333998.M2A_1541 1.202e-116 389.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2TRQG@28211|Alphaproteobacteria,4BPS7@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N TGS3_k127_2164399_8 1247963.JPHU01000006_gene126 7.688e-48 178.0 COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,2TS7W@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase TGS3_k127_2164399_6 1247963.JPHU01000001_gene1836 1.255e-70 250.0 COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2U5E5@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Necessary for normal cell division and for the maintenance of normal septation engB - - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 TGS3_k127_2164399_2 670292.JH26_22720 6.608e-159 520.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2TSTJ@28211|Alphaproteobacteria,1JS60@119045|Methylobacteriaceae 28211|Alphaproteobacteria U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas TGS3_k127_2164399_9 1112212.JH584235_gene3477 1.349e-25 113.0 COG0594@1|root,COG0594@2|Bacteria,1N6QY@1224|Proteobacteria,2UFAB@28211|Alphaproteobacteria,2K5Y4@204457|Sphingomonadales 204457|Sphingomonadales J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P TGS3_k127_2164399_7 1247963.JPHU01000001_gene1832 5.257e-70 245.0 COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,2U6DE@28211|Alphaproteobacteria 28211|Alphaproteobacteria G SNARE associated golgi protein merA_1 - - - - - - - - - - - SNARE_assoc TGS3_k127_2164399_1 1123229.AUBC01000003_gene2214 6.663e-164 528.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TU0K@28211|Alphaproteobacteria,3JUIP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain merA - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim TGS3_k127_2164399_5 402881.Plav_0305 1.572e-94 332.0 COG0642@1|root,COG0642@2|Bacteria,1QYPP@1224|Proteobacteria,2TXUU@28211|Alphaproteobacteria 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c TGS3_k127_2164399_0 648757.Rvan_2422 1.368e-209 666.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,3N6QE@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria M Gamma-glutamyltranspeptidase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept TGS3_k127_2164399_4 1161401.ASJA01000006_gene1895 9.573e-104 346.0 COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2TRDC@28211|Alphaproteobacteria,43WBS@69657|Hyphomonadaceae 28211|Alphaproteobacteria EQ COG3191 L-aminopeptidase D-esterase - - - - - - - - - - - - Peptidase_S58 TGS3_k127_2164399_3 1211115.ALIQ01000145_gene1032 1.958e-112 364.0 COG0583@1|root,COG0583@2|Bacteria,1MU2E@1224|Proteobacteria,2TUNU@28211|Alphaproteobacteria,3NCF2@45404|Beijerinckiaceae 28211|Alphaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate TGS3_k127_217407_0 237727.NAP1_00165 2.553e-184 583.0 COG1874@1|root,COG1874@2|Bacteria,1MUVR@1224|Proteobacteria,2TTC5@28211|Alphaproteobacteria,2K27Y@204457|Sphingomonadales 204457|Sphingomonadales G beta-galactosidase - - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M TGS3_k127_217407_2 991905.SL003B_3339 5.067e-101 339.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2TS7C@28211|Alphaproteobacteria,4BPUR@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria H Quinolinate phosphoribosyl transferase, C-terminal domain nadC - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N TGS3_k127_217407_1 1247963.JPHU01000001_gene2165 3.499e-155 506.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2TS0E@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C TGS3_k127_2180412_3 28444.JODQ01000014_gene6630 4.119e-09 58.0 COG1621@1|root,COG1621@2|Bacteria,2IAXM@201174|Actinobacteria 201174|Actinobacteria G Belongs to the glycosyl hydrolase 68 family lsdA - 2.4.1.10 ko:K00692 ko00500,ko01100,ko02020,map00500,map01100,map02020 - R05140 RC00077 ko00000,ko00001,ko01000,ko01003 - GH68 - Glyco_hydro_68 TGS3_k127_2180412_2 1123487.KB892866_gene1620 7.624e-120 396.0 COG0153@1|root,COG0153@2|Bacteria,1MVQD@1224|Proteobacteria,2VJR7@28216|Betaproteobacteria 28216|Betaproteobacteria G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK - 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg TGS3_k127_2180412_0 598467.BrE312_1240 7.533e-136 440.0 COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,1RMDK@1236|Gammaproteobacteria 1236|Gammaproteobacteria H galactose-1-phosphate uridylyltransferase galT GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_0842,iYL1228.KPN_00772 GalP_UDP_tr_C,GalP_UDP_transf TGS3_k127_2180412_1 395495.Lcho_3246 4.551e-125 409.0 COG3345@1|root,COG3345@2|Bacteria,1MWTQ@1224|Proteobacteria,2VPKQ@28216|Betaproteobacteria,1KN01@119065|unclassified Burkholderiales 28216|Betaproteobacteria G Glycosyl hydrolase family 36 N-terminal domain - - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase TGS3_k127_2235597_1 272568.GDI2052 1.799e-29 121.0 COG5425@1|root,COG5425@2|Bacteria,1N08I@1224|Proteobacteria,2UBVR@28211|Alphaproteobacteria 28211|Alphaproteobacteria E PFAM Usg family protein usg - - - - - - - - - - - Usg TGS3_k127_2235597_0 1280954.HPO_03159 5.04e-167 535.0 COG0773@1|root,COG0773@2|Bacteria,1MVCG@1224|Proteobacteria,2TTDN@28211|Alphaproteobacteria,43Z86@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Mur ligase family, catalytic domain - - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M TGS3_k127_2249606_2 1367847.JCM7686_2137 5.301e-73 249.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TQRZ@28211|Alphaproteobacteria,2PV3H@265|Paracoccus 28211|Alphaproteobacteria S ABC transporter yheS - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_Xtn TGS3_k127_2249606_3 1082931.KKY_1038 3.599e-68 236.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2U5CS@28211|Alphaproteobacteria,3N6VX@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK TGS3_k127_2249606_1 1161401.ASJA01000004_gene2154 1.972e-108 361.0 COG3000@1|root,COG3000@2|Bacteria,1NR7X@1224|Proteobacteria,2TT68@28211|Alphaproteobacteria,43W7D@69657|Hyphomonadaceae 28211|Alphaproteobacteria I COG3000 Sterol desaturase - - - - - - - - - - - - FA_hydroxylase TGS3_k127_2249606_0 1122135.KB893146_gene1432 1.344e-153 514.0 COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2U0Y1@28211|Alphaproteobacteria 28211|Alphaproteobacteria T histidine kinase A domain protein - - - - - - - - - - - - HATPase_c,HisKA,MHYT,Response_reg TGS3_k127_2256367_2 1236542.BALM01000001_gene353 3.26e-14 74.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,2Q9DF@267890|Shewanellaceae 1236|Gammaproteobacteria P ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA GO:0003674,GO:0005215,GO:0005451,GO:0005488,GO:0005543,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006875,GO:0006883,GO:0006885,GO:0006950,GO:0006970,GO:0008150,GO:0008289,GO:0008324,GO:0009628,GO:0009651,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0035725,GO:0042592,GO:0043157,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051453,GO:0055065,GO:0055067,GO:0055078,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:1901611,GO:1901612,GO:1902600 - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - iSF_1195.SF0016,iSFxv_1172.SFxv_0017,iS_1188.S0018 Na_H_antiport_1 TGS3_k127_2256367_0 398580.Dshi_0727 3.468e-98 329.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2TSUS@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator - - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate TGS3_k127_2256367_1 391600.ABRU01000050_gene252 3.472e-43 168.0 COG4774@1|root,COG4774@2|Bacteria,1QVG7@1224|Proteobacteria,2TV9I@28211|Alphaproteobacteria,2KG50@204458|Caulobacterales 204458|Caulobacterales P TonB-dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec TGS3_k127_2256945_0 1247963.JPHU01000012_gene860 1.519e-110 370.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TT2C@28211|Alphaproteobacteria 28211|Alphaproteobacteria FP exopolyphosphatase ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA TGS3_k127_2256945_2 1380394.JADL01000001_gene2267 1.196e-21 103.0 COG1983@1|root,COG1983@2|Bacteria,1NECC@1224|Proteobacteria,2UEYZ@28211|Alphaproteobacteria,2JTP5@204441|Rhodospirillales 204441|Rhodospirillales KT PspC domain - - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC TGS3_k127_2256945_3 1280949.HAD_02750 2.011e-14 75.0 2EH78@1|root,33AZ2@2|Bacteria,1NJ6T@1224|Proteobacteria,2UMFP@28211|Alphaproteobacteria,43YPE@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Phage shock protein B - - - ko:K03970 - - - - ko00000,ko02048 - - - PspB TGS3_k127_2256945_1 1177928.TH2_00740 1.242e-63 227.0 COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,2U6CN@28211|Alphaproteobacteria,2JRRW@204441|Rhodospirillales 204441|Rhodospirillales KT PspA/IM30 family - - - ko:K03969 - - - - ko00000 - - - PspA_IM30 TGS3_k127_2283340_0 1122613.ATUP01000001_gene371 5.996e-87 292.0 COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2TU3T@28211|Alphaproteobacteria,43WEZ@69657|Hyphomonadaceae 28211|Alphaproteobacteria P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodB - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N TGS3_k127_2283340_1 190650.CC_1987 2.405e-16 88.0 COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2U08T@28211|Alphaproteobacteria,2KH6E@204458|Caulobacterales 204458|Caulobacterales I Squalene/phytoene synthase - - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY TGS3_k127_2283340_2 269796.Rru_A2038 0.0001739 50.0 COG1225@1|root,COG1391@1|root,COG1225@2|Bacteria,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2TRY7@28211|Alphaproteobacteria,2JPFA@204441|Rhodospirillales 204441|Rhodospirillales H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE TGS3_k127_2285129_10 366602.Caul_2506 5.392e-54 198.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2TQKD@28211|Alphaproteobacteria,2KFTG@204458|Caulobacterales 204458|Caulobacterales E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N TGS3_k127_2285129_0 870187.Thini_1785 2.299e-222 693.0 COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,1RSA3@1236|Gammaproteobacteria 1236|Gammaproteobacteria M protein conserved in bacteria - - - - - - - - - - - - DUF1343 TGS3_k127_2285129_13 1449076.JOOE01000001_gene2334 5.555e-34 138.0 2C0PI@1|root,32VVI@2|Bacteria,1N1H7@1224|Proteobacteria,2UE1P@28211|Alphaproteobacteria,2K60G@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - TGS3_k127_2285129_1 1247963.JPHU01000008_gene2811 1.28e-198 633.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria 28211|Alphaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C TGS3_k127_2285129_9 693986.MOC_5993 1.215e-60 214.0 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2TSC9@28211|Alphaproteobacteria,1JRMJ@119045|Methylobacteriaceae 28211|Alphaproteobacteria J binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N TGS3_k127_2285129_14 314260.PB2503_00822 9.565e-33 128.0 COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2UC13@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 TGS3_k127_2285129_11 1333998.M2A_2263 3.078e-48 184.0 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2U767@28211|Alphaproteobacteria,4BQK0@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 TGS3_k127_2285129_3 1122137.AQXF01000004_gene1431 9.106e-144 470.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2TRPX@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA - - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH TGS3_k127_2285129_4 1333998.M2A_1185 1.47e-112 371.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2TRTT@28211|Alphaproteobacteria,4BPBU@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria I malonyl CoA-acyl carrier protein transacylase fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 TGS3_k127_2285129_6 1479238.JQMZ01000001_gene1036 1.116e-104 345.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2TQZG@28211|Alphaproteobacteria,43WQU@69657|Hyphomonadaceae 28211|Alphaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 TGS3_k127_2285129_12 1247963.JPHU01000007_gene1587 5.267e-36 137.0 COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2UBWW@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding TGS3_k127_2285129_2 1247963.JPHU01000007_gene1588 1.459e-193 612.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2TR32@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt TGS3_k127_2285129_5 1247963.JPHU01000007_gene1589 3.4e-110 366.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2TR89@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG TGS3_k127_2285129_8 402881.Plav_3355 4.179e-72 253.0 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2TS81@28211|Alphaproteobacteria,1JNYY@119043|Rhodobiaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF1732) yicC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - DUF1732,YicC_N TGS3_k127_2285129_7 1247963.JPHU01000007_gene1591 2.315e-74 256.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2TSCQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin TGS3_k127_2294220_1 1247963.JPHU01000001_gene1978 9.107e-41 156.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2UDUF@28211|Alphaproteobacteria 28211|Alphaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme TGS3_k127_2294220_2 1123267.JONN01000001_gene2094 2.319e-36 144.0 2EH9H@1|root,33B1D@2|Bacteria,1NV7J@1224|Proteobacteria,2UXUY@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_2294220_0 551275.KB899544_gene1546 1.395e-63 237.0 COG1196@1|root,COG1196@2|Bacteria,1MXPN@1224|Proteobacteria,2TRG3@28211|Alphaproteobacteria,43Z1D@69657|Hyphomonadaceae 28211|Alphaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - TGS3_k127_2294928_0 1247963.JPHU01000007_gene1607 8.147e-265 829.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS2I@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdJ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_2_N,Ribonuc_red_lgC TGS3_k127_2294928_1 633149.Bresu_2208 7.452e-10 70.0 COG1357@1|root,COG1357@2|Bacteria,1RIV8@1224|Proteobacteria,2UAGS@28211|Alphaproteobacteria,2KGQ9@204458|Caulobacterales 204458|Caulobacterales S Pentapeptide repeat protein - - - - - - - - - - - - Pentapeptide TGS3_k127_231609_5 84531.JMTZ01000043_gene1221 2.709e-123 409.0 COG5434@1|root,COG5434@2|Bacteria,1MUGF@1224|Proteobacteria,1RS20@1236|Gammaproteobacteria,1X4S8@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - - TGS3_k127_231609_2 1123059.KB823011_gene1438 1.788e-163 534.0 COG3420@1|root,COG3420@2|Bacteria,1QUPB@1224|Proteobacteria,2TTFV@28211|Alphaproteobacteria,4414Y@69657|Hyphomonadaceae 28211|Alphaproteobacteria P Periplasmic copper-binding protein (NosD) - - - - - - - - - - - - Beta_helix TGS3_k127_231609_6 391619.PGA1_262p02260 4.781e-119 409.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase barA_3 - 2.7.13.1 ko:K05962 - - - - ko00000,ko01000 - - - GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg TGS3_k127_231609_7 1121949.AQXT01000002_gene974 4.844e-108 370.0 COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,2TSN9@28211|Alphaproteobacteria,43Z9W@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Belongs to the amidase family - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase,TAT_signal TGS3_k127_231609_8 1537715.JQFJ01000002_gene1767 3.211e-101 333.0 COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,2TS67@28211|Alphaproteobacteria,2K0NC@204457|Sphingomonadales 204457|Sphingomonadales F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 TGS3_k127_231609_12 414684.RC1_3361 1.635e-25 111.0 COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria,2JTEV@204441|Rhodospirillales 204441|Rhodospirillales F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purS - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - PurS TGS3_k127_231609_0 1038859.AXAU01000001_gene3524 3.625e-169 544.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,2U0BW@28211|Alphaproteobacteria,3JU7T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Sodium proton antiporter, NhaD family - - - - - - - - - - - - - TGS3_k127_231609_1 1297865.APJD01000001_gene6006 2.584e-164 528.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,2U0BW@28211|Alphaproteobacteria,3JU7T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Sodium proton antiporter, NhaD family - - - - - - - - - - - - - TGS3_k127_231609_4 493475.GARC_0669 5.839e-131 433.0 COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1RZXV@1236|Gammaproteobacteria,465DH@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20,Peptidase_M28 TGS3_k127_231609_13 314260.PB2503_07644 8.364e-25 113.0 2AF7U@1|root,330UK@2|Bacteria,1NF8Z@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - TGS3_k127_231609_3 1247963.JPHU01000010_gene2253 4.883e-138 443.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2TR8D@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt TGS3_k127_231609_10 935261.JAGL01000003_gene3012 4.82e-36 142.0 COG5467@1|root,COG5467@2|Bacteria,1MZRN@1224|Proteobacteria,2UC1G@28211|Alphaproteobacteria,43KI7@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF1476) - - - - - - - - - - - - DUF1476 TGS3_k127_231609_9 279238.Saro_0875 1.971e-87 296.0 COG1028@1|root,COG1028@2|Bacteria,1MUPX@1224|Proteobacteria,2TT6C@28211|Alphaproteobacteria,2K269@204457|Sphingomonadales 204457|Sphingomonadales IQ KR domain - - - - - - - - - - - - adh_short_C2 TGS3_k127_231609_11 1144307.PMI04_00991 5.333e-27 116.0 2EB0S@1|root,3351M@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - TGS3_k127_2317192_1 1247963.JPHU01000005_gene255 8.742e-61 216.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2TUG7@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family rlmB - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind TGS3_k127_2317192_0 1280950.HJO_12786 2.399e-246 773.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,43X6D@69657|Hyphomonadaceae 28211|Alphaproteobacteria CG alcohol dehydrogenase - - 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 TGS3_k127_2348346_2 1247963.JPHU01000009_gene2325 3.602e-112 371.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2TSHM@28211|Alphaproteobacteria 28211|Alphaproteobacteria J An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era - - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 TGS3_k127_2348346_6 314260.PB2503_08394 2.512e-80 273.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2TTIA@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm TGS3_k127_2348346_4 1247963.JPHU01000009_gene2327 6.224e-94 315.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 TGS3_k127_2348346_10 1410620.SHLA_14c001040 4.644e-59 212.0 COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2U77S@28211|Alphaproteobacteria,4BDYE@82115|Rhizobiaceae 28211|Alphaproteobacteria I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS TGS3_k127_2348346_8 1502850.FG91_01545 1.428e-75 261.0 COG0625@1|root,COG0625@2|Bacteria,1RJVR@1224|Proteobacteria,2U5SU@28211|Alphaproteobacteria,2K42G@204457|Sphingomonadales 204457|Sphingomonadales O Glutathione S-transferase - - - - - - - - - - - - GST_C_2,GST_C_3,GST_N_3 TGS3_k127_2348346_3 1121861.KB899912_gene1102 5.339e-102 339.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2TTTF@28211|Alphaproteobacteria,2JPM4@204441|Rhodospirillales 204441|Rhodospirillales H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ - 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ TGS3_k127_2348346_11 395965.Msil_3484 6.865e-39 149.0 COG4113@1|root,COG4113@2|Bacteria,1NEE2@1224|Proteobacteria,2UJ3R@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - - - - - - - - - - PIN TGS3_k127_2348346_14 395965.Msil_3485 3.042e-10 64.0 2A6UU@1|root,30VP8@2|Bacteria,1NQ5B@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - TGS3_k127_2348346_7 1247963.JPHU01000009_gene2330 3.109e-77 264.0 COG0461@1|root,COG0461@2|Bacteria,1RIC5@1224|Proteobacteria,2TUX2@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran TGS3_k127_2348346_1 1247963.JPHU01000009_gene2331 4.659e-219 706.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2TQNY@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance spoT - 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS TGS3_k127_2348346_12 1247963.JPHU01000009_gene2332 4.971e-33 133.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2U9BQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 TGS3_k127_2348346_13 394221.Mmar10_1577 2.294e-30 125.0 COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2U8D6@28211|Alphaproteobacteria,43YI5@69657|Hyphomonadaceae 28211|Alphaproteobacteria H COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase folK - 2.7.6.3,4.1.2.25 ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503,R03504 RC00002,RC00017,RC00721,RC00943 ko00000,ko00001,ko00002,ko01000 - - - HPPK TGS3_k127_2348346_9 1247963.JPHU01000009_gene2334 8.697e-75 256.0 COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,2TU5M@28211|Alphaproteobacteria 28211|Alphaproteobacteria L NYN domain MA20_36560 - - - - - - - - - - - NYN TGS3_k127_2348346_5 402881.Plav_2864 2.541e-81 276.0 COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,2TSUP@28211|Alphaproteobacteria,1JNUW@119043|Rhodobiaceae 28211|Alphaproteobacteria L UreE urease accessory protein, C-terminal domain ung - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG TGS3_k127_2348346_0 394221.Mmar10_1510 3.283e-223 704.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,43W6H@69657|Hyphomonadaceae 28211|Alphaproteobacteria V Efflux ABC transporter, permease ATP-binding protein msbA2 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran TGS3_k127_2349052_0 1112217.PPL19_19757 2.104e-73 260.0 COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,1RRSK@1236|Gammaproteobacteria 1236|Gammaproteobacteria K esterase of the alpha-beta hydrolase superfamily plpD - - ko:K07001 - - - - ko00000 - - - Bac_surface_Ag,POTRA,Patatin TGS3_k127_2349052_1 1033991.RLEG12_19025 2.563e-62 220.0 COG1309@1|root,COG1309@2|Bacteria,1N11B@1224|Proteobacteria,2UIUU@28211|Alphaproteobacteria,4B9RX@82115|Rhizobiaceae 28211|Alphaproteobacteria K Transcriptional regulator - - - - - - - - - - - - TetR_N TGS3_k127_2350209_2 1248916.ANFY01000006_gene1961 8.204e-26 124.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1N7YB@1224|Proteobacteria,2V7CZ@28211|Alphaproteobacteria,2K2SU@204457|Sphingomonadales 204457|Sphingomonadales S TIR domain - - - - - - - - - - - - TIR_2 TGS3_k127_2350209_0 402881.Plav_3054 1.152e-166 531.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2TR87@28211|Alphaproteobacteria,1JN49@119043|Rhodobiaceae 28211|Alphaproteobacteria J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT TGS3_k127_2350209_1 1123229.AUBC01000004_gene3257 4.662e-126 414.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2TS0D@28211|Alphaproteobacteria,3JUTD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth TGS3_k127_2350209_3 1161401.ASJA01000009_gene1814 1.229e-07 53.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2TQRQ@28211|Alphaproteobacteria,43WQA@69657|Hyphomonadaceae 28211|Alphaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV TGS3_k127_2373460_3 1122612.AUBA01000010_gene59 2.042e-05 46.0 COG3474@1|root,COG3474@2|Bacteria,1MZGS@1224|Proteobacteria,2UCUT@28211|Alphaproteobacteria,2K4M2@204457|Sphingomonadales 204457|Sphingomonadales C Cytochrome c - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C TGS3_k127_2373460_2 633149.Bresu_0678 2.474e-61 220.0 COG3637@1|root,COG3637@2|Bacteria,1R191@1224|Proteobacteria,2TYYV@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Protein of unknown function (DUF2490) - - - - - - - - - - - - DUF2490 TGS3_k127_2373460_0 1437882.AZRU01000049_gene5270 4.62e-105 347.0 COG0300@1|root,COG0300@2|Bacteria,1R7MT@1224|Proteobacteria,1S0XC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - ko:K07124 - - - - ko00000 - - - adh_short TGS3_k127_2373460_1 595537.Varpa_5271 3.737e-84 280.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VH9Y@28216|Betaproteobacteria,4AAA7@80864|Comamonadaceae 28216|Betaproteobacteria C acyl-CoA dehydrogenase - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N TGS3_k127_2373936_0 314260.PB2503_08334 3.386e-89 302.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2TTMG@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15,2.7.6.3 ko:K00796,ko:K13941,ko:K18824 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503 RC00002,RC00017,RC00121,RC00842 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Pterin_bind TGS3_k127_2373936_1 566466.NOR53_396 2.96e-80 283.0 COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,1S1CZ@1236|Gammaproteobacteria,1J740@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases - - 3.5.2.6 ko:K17837 ko01501,map01501 - R06363 RC01499 ko00000,ko00001,ko01000 - - - Lactamase_B TGS3_k127_2373936_2 1537715.JQFJ01000002_gene1482 5.987e-36 141.0 COG2244@1|root,COG2244@2|Bacteria,1RC9S@1224|Proteobacteria,2U63T@28211|Alphaproteobacteria,2K3HG@204457|Sphingomonadales 204457|Sphingomonadales S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3 TGS3_k127_2387773_2 69395.JQLZ01000004_gene638 2.993e-31 127.0 COG3838@1|root,COG3838@2|Bacteria,1N55M@1224|Proteobacteria,2UD7V@28211|Alphaproteobacteria,2KJB2@204458|Caulobacterales 204458|Caulobacterales U TrbC/VIRB2 family - - - - - - - - - - - - TrbC TGS3_k127_2387773_1 69395.JQLZ01000006_gene2285 1.099e-37 145.0 COG3702@1|root,COG3702@2|Bacteria,1N1YI@1224|Proteobacteria,2UDDW@28211|Alphaproteobacteria,2KHE9@204458|Caulobacterales 204458|Caulobacterales U Type IV secretory pathway, VirB3-like protein - - - ko:K03198 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - VirB3 TGS3_k127_2387773_0 69395.JQLZ01000006_gene2286 4.224e-306 955.0 COG3451@1|root,COG3451@2|Bacteria,1MXH0@1224|Proteobacteria,2TR1U@28211|Alphaproteobacteria,2KEYI@204458|Caulobacterales 204458|Caulobacterales U Type VI secretion protein - - - ko:K03199 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - CagE_TrbE_VirB TGS3_k127_2392536_6 1280954.HPO_08269 6.129e-16 80.0 COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2U0BA@28211|Alphaproteobacteria,43WZ6@69657|Hyphomonadaceae 28211|Alphaproteobacteria S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III - - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 TGS3_k127_2392536_4 330214.NIDE3609 2.12e-26 113.0 COG4221@1|root,COG4221@2|Bacteria 2|Bacteria IQ oxidoreductase activity - - - - - - - - - - - - adh_short TGS3_k127_2392536_5 864069.MicloDRAFT_00022120 1.481e-24 108.0 COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,2TQRM@28211|Alphaproteobacteria,1JR0F@119045|Methylobacteriaceae 28211|Alphaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family MA20_02360 - - - - - - - - - - - adh_short TGS3_k127_2392536_1 744979.R2A130_0277 1.721e-44 169.0 COG5470@1|root,COG5470@2|Bacteria,1MWI7@1224|Proteobacteria,2U0S6@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF1330) MA20_23360 - - - - - - - - - - - DUF1330 TGS3_k127_2392536_2 744979.R2A130_2674 4.474e-44 166.0 2BSQ3@1|root,32MSX@2|Bacteria,1RJG0@1224|Proteobacteria,2U9H9@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_2392536_3 1280954.HPO_06137 5.586e-39 154.0 COG4731@1|root,COG4731@2|Bacteria,1MZWJ@1224|Proteobacteria,2UDVG@28211|Alphaproteobacteria,43XZU@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2147) - - - - - - - - - - - - - TGS3_k127_2392536_0 1247963.JPHU01000014_gene959 1.322e-174 556.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria 28211|Alphaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl,Transket_pyr,Transketolase_C TGS3_k127_243617_1 323848.Nmul_A2168 4.248e-35 137.0 COG3422@1|root,COG3422@2|Bacteria,1N0S6@1224|Proteobacteria,2VUA2@28216|Betaproteobacteria,373DS@32003|Nitrosomonadales 28216|Betaproteobacteria S Domain of unknown function (DUF1508) - - - ko:K09946 - - - - ko00000 - - - DUF1508 TGS3_k127_243617_0 1247963.JPHU01000001_gene1756 0.0 1046.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2TS2B@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA helicase uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C TGS3_k127_243617_3 926566.Terro_1299 1.209e-13 74.0 COG4914@1|root,COG4914@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF2204 TGS3_k127_243617_2 1247963.JPHU01000005_gene279 4.43e-28 117.0 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2TTP3@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA TGS3_k127_2455414_0 1247963.JPHU01000002_gene2564 2.239e-107 351.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2TRMC@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C TGS3_k127_2455414_1 509190.Cseg_2908 4.215e-88 301.0 COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,2U45K@28211|Alphaproteobacteria,2KGD8@204458|Caulobacterales 204458|Caulobacterales S methyltransferase - - - - - - - - - - - - Methyltransf_11 TGS3_k127_2455414_2 1247963.JPHU01000002_gene2562 2.758e-54 198.0 COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2TRUF@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg TGS3_k127_2456392_10 1280941.HY2_15720 7.977e-05 49.0 COG2165@1|root,COG2165@2|Bacteria,1NH8A@1224|Proteobacteria,2UK2Q@28211|Alphaproteobacteria,43YW6@69657|Hyphomonadaceae 28211|Alphaproteobacteria NU General secretion pathway protein I - - - ko:K02458 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSI TGS3_k127_2456392_5 1247963.JPHU01000001_gene2140 1.171e-30 133.0 COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,2UAXM@28211|Alphaproteobacteria 28211|Alphaproteobacteria U General secretion pathway protein J gspJ - - ko:K02459 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSJ TGS3_k127_2456392_4 190650.CC_0180 6.56e-37 152.0 COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,2U6QZ@28211|Alphaproteobacteria,2KGAP@204458|Caulobacterales 204458|Caulobacterales U Type II secretion system (T2SS), protein K - - - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSK TGS3_k127_2456392_6 1161401.ASJA01000004_gene2260 1.076e-20 105.0 COG3297@1|root,COG3297@2|Bacteria,1N0FQ@1224|Proteobacteria,2UEET@28211|Alphaproteobacteria,43YM8@69657|Hyphomonadaceae 28211|Alphaproteobacteria U COG3297 Type II secretory pathway, component PulL gspL - - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL TGS3_k127_2456392_9 314254.OA2633_12025 1.856e-07 60.0 COG3149@1|root,COG3149@2|Bacteria 2|Bacteria U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins gspM - - ko:K02462 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSM TGS3_k127_2456392_8 1121949.AQXT01000002_gene908 2.804e-08 64.0 2EGH8@1|root,33A9B@2|Bacteria,1NKAJ@1224|Proteobacteria,2UMM7@28211|Alphaproteobacteria,43YG3@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Type II secretion system (T2SS), protein N gspN - - ko:K02463 ko05111,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSN TGS3_k127_2456392_3 472759.Nhal_2109 6.117e-37 150.0 COG0428@1|root,COG0428@2|Bacteria,1PMN6@1224|Proteobacteria,1SIQH@1236|Gammaproteobacteria,1X1XX@135613|Chromatiales 135613|Chromatiales P ZIP Zinc transporter - - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip TGS3_k127_2456392_2 1397528.Q671_06385 6.057e-88 302.0 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1XK05@135619|Oceanospirillales 135619|Oceanospirillales P cation diffusion facilitator family transporter - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux TGS3_k127_2456392_1 314260.PB2503_09604 1.691e-101 347.0 COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,2TT7I@28211|Alphaproteobacteria 28211|Alphaproteobacteria M polymerase - - - - - - - - - - - - Wzy_C TGS3_k127_2456392_0 1282362.AEAC466_00615 3.586e-112 378.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2TSAE@28211|Alphaproteobacteria,2KFBE@204458|Caulobacterales 204458|Caulobacterales S alpha-2-macroglobulin - - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl TGS3_k127_246237_1 1177179.A11A3_04540 5.095e-23 103.0 COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,1XK7S@135619|Oceanospirillales 135619|Oceanospirillales T Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc TGS3_k127_246237_0 317655.Sala_1664 1.633e-273 862.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2U2X6@28211|Alphaproteobacteria,2KEB6@204457|Sphingomonadales 204457|Sphingomonadales P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec TGS3_k127_2466203_2 551275.KB899544_gene1583 1.211e-40 166.0 COG1216@1|root,COG1216@2|Bacteria,1RAKR@1224|Proteobacteria,2U4HT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Glycosyltransferase family 87 - - - - - - - - - - - - GT87 TGS3_k127_2466203_0 1479238.JQMZ01000001_gene138 3.568e-66 234.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2TR2V@28211|Alphaproteobacteria,43WEG@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family gluQ - - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c TGS3_k127_2480419_1 1161401.ASJA01000020_gene576 1.436e-95 316.0 COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2TSFF@28211|Alphaproteobacteria,43WAQ@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Glycine dehydrogenase (aminomethyl-transferring) gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5,GDC-P TGS3_k127_2480419_2 1161401.ASJA01000020_gene581 5.003e-70 251.0 COG1835@1|root,COG1835@2|Bacteria,1RDAA@1224|Proteobacteria,2U8A0@28211|Alphaproteobacteria,43XDY@69657|Hyphomonadaceae 28211|Alphaproteobacteria I exopolysaccharide production protein ExoZ - - - - - - - - - - - - Acyl_transf_3 TGS3_k127_2480419_3 314260.PB2503_02147 3.616e-44 168.0 COG0711@1|root,COG0711@2|Bacteria,1N0P5@1224|Proteobacteria,2U5DD@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B TGS3_k127_2480419_4 1247963.JPHU01000001_gene1987 5.194e-37 150.0 COG0711@1|root,COG0711@2|Bacteria,1MZGU@1224|Proteobacteria,2UBVW@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF2 - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B TGS3_k127_2480419_5 573065.Astex_1115 9.811e-14 77.0 COG0636@1|root,COG0636@2|Bacteria,1MZBU@1224|Proteobacteria,2UFPN@28211|Alphaproteobacteria,2KH88@204458|Caulobacterales 204458|Caulobacterales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C TGS3_k127_2480419_0 1247963.JPHU01000001_gene1985 4.47e-100 332.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2TRNV@28211|Alphaproteobacteria 28211|Alphaproteobacteria C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A TGS3_k127_2480419_6 1120956.JHZK01000028_gene484 7.498e-09 62.0 COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,2UFJJ@28211|Alphaproteobacteria,1JPI4@119043|Rhodobiaceae 28211|Alphaproteobacteria S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter atpI - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 TGS3_k127_248130_2 1430440.MGMSRv2_0961 3.844e-08 55.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2TRJX@28211|Alphaproteobacteria,2JP8G@204441|Rhodospirillales 204441|Rhodospirillales M Belongs to the KdsA family kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 TGS3_k127_248130_1 1238182.C882_3053 3.296e-103 344.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2TU5X@28211|Alphaproteobacteria,2JPK0@204441|Rhodospirillales 204441|Rhodospirillales M Belongs to the SIS family. GutQ KpsF subfamily kpsF - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS TGS3_k127_248130_0 1121033.AUCF01000001_gene1990 1.863e-151 491.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2TSDP@28211|Alphaproteobacteria,2JQ32@204441|Rhodospirillales 204441|Rhodospirillales L Belongs to the DNA photolyase family phrB - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 TGS3_k127_2488506_2 269796.Rru_A1883 5.694e-33 133.0 COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,2TQQD@28211|Alphaproteobacteria,2JQ7P@204441|Rhodospirillales 204441|Rhodospirillales P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA TGS3_k127_2488506_0 1245469.S58_44540 5.412e-264 820.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2TRN0@28211|Alphaproteobacteria,3JSTM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase TGS3_k127_2488506_1 627192.SLG_08180 5.762e-122 400.0 COG1609@1|root,COG1609@2|Bacteria,1MW7E@1224|Proteobacteria,2TVGC@28211|Alphaproteobacteria,2K05K@204457|Sphingomonadales 204457|Sphingomonadales K LacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 TGS3_k127_2503505_1 114615.BRADO1618 8.047e-166 525.0 COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,2TSKC@28211|Alphaproteobacteria,3JW6P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Belongs to the NifH BchL ChlL family bchX - 1.3.7.14,1.3.7.15 ko:K11333 ko00860,ko01110,map00860,map01110 - R09053,R09060 RC01008 ko00000,ko00001,ko01000 - - - Fer4_NifH TGS3_k127_2503505_5 1120956.JHZK01000006_gene639 5.698e-114 376.0 COG1063@1|root,COG1063@2|Bacteria,1MVZC@1224|Proteobacteria,2TRM6@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Dehydrogenase bchC - 1.1.1.396 ko:K11337 ko00860,ko01110,map00860,map01110 - R09055 RC01377 ko00000,ko00001,ko01000 - - - ADH_N TGS3_k127_2503505_6 426117.M446_3695 1.478e-113 377.0 COG0500@1|root,COG2226@2|Bacteria,1MW7J@1224|Proteobacteria,2TSZC@28211|Alphaproteobacteria,1JZHF@119045|Methylobacteriaceae 28211|Alphaproteobacteria Q O-methyltransferase crtF - 2.1.1.210 ko:K09846 ko00906,ko01100,map00906,map01100 - R07521,R07524,R07527,R07529,R07533,R07535 RC00003,RC02082 ko00000,ko00001,ko01000 - - - Dimerisation2,Methyltransf_2 TGS3_k127_2503505_8 1120956.JHZK01000006_gene637 5.564e-100 334.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2TR79@28211|Alphaproteobacteria,1JNTZ@119043|Rhodobiaceae 28211|Alphaproteobacteria H Polyprenyl synthetase - - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt TGS3_k127_2503505_3 288000.BBta_6441 6.021e-144 479.0 COG1233@1|root,COG1233@2|Bacteria,1MX1C@1224|Proteobacteria,2TS2R@28211|Alphaproteobacteria,3JV3B@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Flavin containing amine oxidoreductase crtD - 1.3.99.27 ko:K09845 ko00906,ko01100,map00906,map01100 - R07517,R07520,R07523,R07534 RC02080 ko00000,ko00001,ko01000 - - - Amino_oxidase TGS3_k127_2503505_9 1112212.JH584235_gene2052 1.202e-85 308.0 COG5621@1|root,COG5621@2|Bacteria,1QPJ4@1224|Proteobacteria,2TVNN@28211|Alphaproteobacteria,2K32K@204457|Sphingomonadales 204457|Sphingomonadales S hydroxyneurosporene synthase - - 4.2.1.131 ko:K09844 ko00906,ko01100,map00906,map01100 - R07516,R07519,R07522,R07528,R07532,R07536,R07539,R07543,R09790 RC00966 ko00000,ko00001,ko01000 - - - - TGS3_k127_2503505_7 1123072.AUDH01000025_gene363 2.485e-105 352.0 COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2TTI0@28211|Alphaproteobacteria,2JPPC@204441|Rhodospirillales 204441|Rhodospirillales I Squalene/phytoene synthase crtB - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY TGS3_k127_2503505_0 1101192.KB910516_gene740 2.227e-231 726.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,1JQUC@119045|Methylobacteriaceae 28211|Alphaproteobacteria Q Phytoene desaturase crtI GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016119,GO:0016120,GO:0016491,GO:0016627,GO:0036094,GO:0042214,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046246,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,5.2.1.13 ko:K09835,ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00097 R04787,R04798,R04800,R07512,R09691,R09692 RC01214,RC01960,RC02088,RC02605 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase TGS3_k127_2503505_10 258594.RPA1511 2.469e-78 272.0 COG2267@1|root,COG2267@2|Bacteria,1QUPE@1224|Proteobacteria,2TT7G@28211|Alphaproteobacteria,3JVX8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Alpha beta hydrolase bchO - - ko:K06049 - - - - ko00000 - - - Abhydrolase_1,Abhydrolase_6 TGS3_k127_2503505_4 1122603.ATVI01000005_gene2862 2.772e-137 455.0 COG1240@1|root,COG1240@2|Bacteria,1MYHV@1224|Proteobacteria,1RS9F@1236|Gammaproteobacteria 1236|Gammaproteobacteria H introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX bchD - 6.6.1.1 ko:K03404 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R03877 RC01012 ko00000,ko00001,ko01000 - - - VWA_2 TGS3_k127_2503505_2 1187851.A33M_0175 4.293e-150 481.0 COG1239@1|root,COG1239@2|Bacteria,1MVD4@1224|Proteobacteria,2TRWU@28211|Alphaproteobacteria,3FE00@34008|Rhodovulum 28211|Alphaproteobacteria H introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX bchI - 6.6.1.1 ko:K03405 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R03877 RC01012 ko00000,ko00001,ko01000 - - - Mg_chelatase TGS3_k127_2527363_0 1247963.JPHU01000004_gene585 4.927e-289 897.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2TR63@28211|Alphaproteobacteria 28211|Alphaproteobacteria T GTP-binding protein TypA typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 TGS3_k127_2540762_5 1247963.JPHU01000001_gene1741 4.025e-52 187.0 COG4957@1|root,COG4957@2|Bacteria,1RGUW@1224|Proteobacteria,2U99M@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator - - - - - - - - - - - - ROS_MUCR TGS3_k127_2540762_0 314260.PB2503_07157 1.013e-196 623.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2TQKT@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT TGS3_k127_2540762_4 1282876.BAOK01000001_gene1905 2.352e-66 229.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2U75W@28211|Alphaproteobacteria,4BQ7B@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone TGS3_k127_2540762_6 1247963.JPHU01000001_gene1737 2.629e-42 160.0 COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2UBQA@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB TGS3_k127_2540762_3 1161401.ASJA01000009_gene1766 4.195e-80 278.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2TTI6@28211|Alphaproteobacteria,43XN4@69657|Hyphomonadaceae 28211|Alphaproteobacteria F Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C TGS3_k127_2540762_11 285535.JOEY01000035_gene3715 6.132e-08 53.0 COG0477@1|root,COG0477@2|Bacteria,2H6BY@201174|Actinobacteria 201174|Actinobacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 TGS3_k127_2540762_8 1333998.M2A_0600 9.921e-35 138.0 COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2U9A5@28211|Alphaproteobacteria,4BQR6@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria K MerR HTH family regulatory protein merR - - - - - - - - - - - MerR_1 TGS3_k127_2540762_7 1207063.P24_04949 5.057e-35 136.0 COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2UCDG@28211|Alphaproteobacteria,2JSQ2@204441|Rhodospirillales 204441|Rhodospirillales K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himA - - ko:K04764 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding TGS3_k127_2540762_1 1247963.JPHU01000003_gene1307 9.691e-135 441.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TR60@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C TGS3_k127_2540762_2 314260.PB2503_01317 2.553e-109 364.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2TR53@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis TGS3_k127_2540762_10 509190.Cseg_1667 1.126e-16 87.0 COG1399@1|root,COG1399@2|Bacteria,1PT3A@1224|Proteobacteria,2V51T@28211|Alphaproteobacteria,2KGXK@204458|Caulobacterales 204458|Caulobacterales S Uncharacterized ACR, COG1399 - - - - - - - - - - - - DUF177 TGS3_k127_2540762_9 588932.JHOF01000018_gene766 4.563e-18 88.0 COG5452@1|root,COG5452@2|Bacteria,1N12T@1224|Proteobacteria,2UCES@28211|Alphaproteobacteria,2KGSB@204458|Caulobacterales 204458|Caulobacterales S Ubiquinol-cytochrome C chaperone - - - ko:K17662 - - - - ko00000,ko03029 - - - Ubiq_cyt_C_chap TGS3_k127_2559748_0 1353531.AZNX01000006_gene5551 4.663e-84 286.0 COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,2TT08@28211|Alphaproteobacteria,4BDPT@82115|Rhizobiaceae 28211|Alphaproteobacteria E Amidinotransferase - - 3.5.3.18 ko:K01482 - - - - ko00000,ko01000,ko04147 - - - Amidinotransf TGS3_k127_2559748_3 1123270.ATUR01000007_gene1287 7.996e-07 59.0 2FB68@1|root,30QV6@2|Bacteria,1NWWK@1224|Proteobacteria,2US5H@28211|Alphaproteobacteria,2K6YE@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - TGS3_k127_2559748_1 1333998.M2A_3268 6.145e-67 231.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,2U760@28211|Alphaproteobacteria,4BQ4R@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N TGS3_k127_2559748_2 551275.KB899544_gene1398 4.892e-62 215.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,2TRXP@28211|Alphaproteobacteria,43X7A@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 TGS3_k127_2568482_1 1247963.JPHU01000002_gene2477 1.083e-74 261.0 COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,2TTX1@28211|Alphaproteobacteria 28211|Alphaproteobacteria O COG1076 DnaJ-domain-containing proteins 1 djlA - - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB TGS3_k127_2568482_0 1131814.JAFO01000001_gene1156 7.078e-241 755.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,3EXXE@335928|Xanthobacteraceae 28211|Alphaproteobacteria E B12 binding domain metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans TGS3_k127_2596616_4 314260.PB2503_02597 2.083e-05 47.0 COG2365@1|root,COG2365@2|Bacteria,1REIM@1224|Proteobacteria,2U7HD@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Protein tyrosine serine phosphatase - - - - - - - - - - - - DUF442,Y_phosphatase3 TGS3_k127_2596616_2 411684.HPDFL43_02315 6.171e-33 128.0 COG0483@1|root,COG0483@2|Bacteria,1N7D7@1224|Proteobacteria,2UF6T@28211|Alphaproteobacteria,43KNI@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Domain of unknown function (DUF4170) MA20_05805 - - - - - - - - - - - DUF4170 TGS3_k127_2596616_1 1247963.JPHU01000005_gene364 6.486e-154 501.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2TSAV@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Zn-dependent proteases and their inactivated homologs pmbA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD TGS3_k127_2596616_0 1188256.BASI01000002_gene3293 2.948e-162 525.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2TQPB@28211|Alphaproteobacteria,3FCKV@34008|Rhodovulum 28211|Alphaproteobacteria E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC TGS3_k127_2596616_3 394221.Mmar10_0409 3.348e-08 62.0 2EF0I@1|root,338TM@2|Bacteria,1NHRK@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - TGS3_k127_2631296_1 1215114.BBIU01000002_gene258 1.637e-37 152.0 COG3307@1|root,COG3307@2|Bacteria,1RCKR@1224|Proteobacteria,1SJKS@1236|Gammaproteobacteria 1236|Gammaproteobacteria M O-Antigen ligase - - - - - - - - - - - - Wzy_C TGS3_k127_2631296_2 1123269.NX02_05860 3.541e-37 157.0 COG1538@1|root,COG1538@2|Bacteria,1NG3P@1224|Proteobacteria,2U6AU@28211|Alphaproteobacteria,2K0JD@204457|Sphingomonadales 204457|Sphingomonadales MU Outer membrane efflux protein - - - ko:K12543 - M00330 - - ko00000,ko00002,ko02000,ko02044 1.B.17,3.A.1.109.4 - - OEP TGS3_k127_2631296_0 999141.GME_14850 1.083e-175 569.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1XIJU@135619|Oceanospirillales 135619|Oceanospirillales V (ABC) transporter - - - - - - - - - - - - ABC_membrane,ABC_tran TGS3_k127_2631296_3 675817.VDA_000880 2.328e-10 65.0 COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,1XSCT@135623|Vibrionales 135623|Vibrionales M COG0845 Membrane-fusion protein lapC - - ko:K12542 - M00330 - - ko00000,ko00002,ko02000,ko02044 3.A.1.109.4,8.A.1 - - Biotin_lipoyl_2,HlyD,HlyD_3,OEP TGS3_k127_2633439_0 1247963.JPHU01000005_gene394 4.867e-108 372.0 COG0845@1|root,COG0845@2|Bacteria,1QYEG@1224|Proteobacteria,2TXQ7@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Domain of unknown function (DUF4175) - - - - - - - - - - - - DUF4175 TGS3_k127_2633439_2 1247963.JPHU01000005_gene393 1.035e-13 81.0 28S2C@1|root,2ZEE4@2|Bacteria,1P8GC@1224|Proteobacteria,2UZ5Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_2633439_1 402881.Plav_1665 7.573e-73 257.0 COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2U5X1@28211|Alphaproteobacteria,1JQ7H@119043|Rhodobiaceae 28211|Alphaproteobacteria I PFAM Alpha beta hydrolase fold-3 domain protein - - - ko:K01066 - - - - ko00000,ko01000 - - - Abhydrolase_3 TGS3_k127_2641552_1 383381.EH30_09320 4.841e-09 61.0 2AHIG@1|root,317W2@2|Bacteria,1NM0G@1224|Proteobacteria,2UNI2@28211|Alphaproteobacteria,2KAN6@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - TGS3_k127_2641552_0 1247963.JPHU01000004_gene463 3.603e-255 805.0 COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,2TRU4@28211|Alphaproteobacteria 28211|Alphaproteobacteria O peptidase, M13 - - 3.4.24.71 ko:K01415,ko:K07386 - - - - ko00000,ko01000,ko01002,ko04147 - - - Peptidase_M13,Peptidase_M13_N TGS3_k127_2644176_4 509190.Cseg_1369 2.829e-06 53.0 COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,2TR4F@28211|Alphaproteobacteria,2KFGT@204458|Caulobacterales 204458|Caulobacterales N FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliM - - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C TGS3_k127_2644176_2 1123503.KB908056_gene1291 2.873e-10 68.0 COG1580@1|root,COG1580@2|Bacteria,1RH5D@1224|Proteobacteria,2U7QV@28211|Alphaproteobacteria,2KGKM@204458|Caulobacterales 204458|Caulobacterales N Controls the rotational direction of flagella during chemotaxis - - - ko:K02415 - - - - ko00000,ko02035 - - - FliL TGS3_k127_2644176_1 1123503.KB908056_gene1292 2.733e-55 201.0 COG4786@1|root,COG4786@2|Bacteria,1PZ24@1224|Proteobacteria,2U06G@28211|Alphaproteobacteria,2KGAM@204458|Caulobacterales 204458|Caulobacterales N Belongs to the flagella basal body rod proteins family flgF - - ko:K02391 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C TGS3_k127_2644176_0 1161401.ASJA01000004_gene2342 3.739e-103 342.0 COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,2TRR4@28211|Alphaproteobacteria,43ZFJ@69657|Hyphomonadaceae 28211|Alphaproteobacteria N the Bradyrhizobium protein in this cluster is associated with the thick flagella flgG - - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C TGS3_k127_2644176_3 1437448.AZRT01000005_gene4360 5.952e-09 66.0 COG1261@1|root,COG1261@2|Bacteria,1MZIR@1224|Proteobacteria,2UDQ2@28211|Alphaproteobacteria,1J2UM@118882|Brucellaceae 28211|Alphaproteobacteria N Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly flgA - - ko:K02386 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - ChapFlgA TGS3_k127_264744_3 376733.IT41_18655 5.464e-28 121.0 COG1073@1|root,COG1073@2|Bacteria,1MX88@1224|Proteobacteria,2TSRE@28211|Alphaproteobacteria,2PU6M@265|Paracoccus 28211|Alphaproteobacteria S Serine aminopeptidase, S33 MA20_24420 - - ko:K06889 - - - - ko00000 - - - Abhydrolase_6,Hydrolase_4 TGS3_k127_264744_0 1121949.AQXT01000002_gene1797 6.656e-105 356.0 COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,2TSPN@28211|Alphaproteobacteria,43WQZ@69657|Hyphomonadaceae 28211|Alphaproteobacteria M COG0438 Glycosyltransferase capM - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 TGS3_k127_264744_2 314260.PB2503_06627 3.915e-52 196.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2TUTN@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG0859 ADP-heptose LPS heptosyltransferase - - - - - - - - - - - - Glyco_transf_9 TGS3_k127_264744_1 394221.Mmar10_0123 2.145e-72 248.0 COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2U58Z@28211|Alphaproteobacteria,43XEN@69657|Hyphomonadaceae 28211|Alphaproteobacteria J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N TGS3_k127_2660992_4 1379701.JPJC01000139_gene1306 3.982e-06 53.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,2K18Q@204457|Sphingomonadales 204457|Sphingomonadales P Cation transporter/ATPase, N-terminus - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase TGS3_k127_2660992_3 1333998.M2A_0131 1.504e-35 143.0 COG1309@1|root,COG1309@2|Bacteria,1N71J@1224|Proteobacteria,2UHJN@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator - - - - - - - - - - - - TetR_N TGS3_k127_2660992_1 1280948.HY36_00010 1.51e-97 340.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2TT75@28211|Alphaproteobacteria,43WP1@69657|Hyphomonadaceae 28211|Alphaproteobacteria I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N TGS3_k127_2660992_0 89187.ISM_06640 7.84e-213 666.0 COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2TTGS@28211|Alphaproteobacteria,46NVD@74030|Roseovarius 28211|Alphaproteobacteria H Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth TGS3_k127_2660992_2 1449049.JONW01000005_gene1754 3.786e-47 177.0 COG0793@1|root,COG0793@2|Bacteria,1N5BU@1224|Proteobacteria,2UM02@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the peptidase S41A family - - - - - - - - - - - - - TGS3_k127_2665048_0 161528.ED21_20784 1.186e-67 239.0 28M5H@1|root,2ZAJ9@2|Bacteria,1RJY2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - TGS3_k127_2665048_3 1121011.AUCB01000004_gene2751 0.0001015 53.0 COG3204@1|root,COG3204@2|Bacteria,4NNIP@976|Bacteroidetes,1I2A1@117743|Flavobacteriia,23I3H@178469|Arenibacter 976|Bacteroidetes S SdiA-regulated - - - - - - - - - - - - SdiA-regulated TGS3_k127_2665048_2 118161.KB235922_gene3936 9.129e-33 137.0 2C4HM@1|root,2ZFRV@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - TGS3_k127_2665048_1 1234595.C725_0856 1.396e-45 173.0 COG0697@1|root,COG0697@2|Bacteria,1RC7K@1224|Proteobacteria,2U0HX@28211|Alphaproteobacteria 28211|Alphaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - ko:K15270 - - - - ko00000,ko02000 2.A.7.3.7 - - EamA TGS3_k127_2704665_2 1231391.AMZF01000014_gene2436 1.37e-34 137.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,2VI08@28216|Betaproteobacteria,3T4AI@506|Alcaligenaceae 28216|Betaproteobacteria NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue outO - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 TGS3_k127_2704665_1 876044.IMCC3088_455 1.473e-62 224.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,1RPSX@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 - R03026 RC00831 ko00000,ko00001,ko01000 - - - ECH_1 TGS3_k127_2704665_0 1040986.ATYO01000008_gene2582 5.396e-201 645.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,43IUP@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh TGS3_k127_2704805_0 113395.AXAI01000001_gene3370 0.0 1235.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,3JVSS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Pyruvate ferredoxin/flavodoxin oxidoreductase MA20_06130 - 1.2.7.8 ko:K04090 - - - - br01601,ko00000,ko01000 - - - POR,TPP_enzyme_C TGS3_k127_2704805_1 1122194.AUHU01000013_gene707 4.032e-100 338.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,4647G@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1448 Aspartate tyrosine aromatic aminotransferase phhC - 2.6.1.1,2.6.1.57 ko:K00813,ko:K00832 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 TGS3_k127_270927_1 627192.SLG_33510 3.195e-171 555.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSQN@28211|Alphaproteobacteria,2KCC8@204457|Sphingomonadales 204457|Sphingomonadales C protein conserved in bacteria - - - - - - - - - - - - DUF885 TGS3_k127_270927_0 1267005.KB911259_gene3816 5.862e-211 662.0 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2TQUS@28211|Alphaproteobacteria,3N6AT@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria H Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 TGS3_k127_270927_2 1282876.BAOK01000002_gene526 4.585e-41 166.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,4BPMV@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G Glucose / Sorbosone dehydrogenase yliI - 1.1.5.2 ko:K00117,ko:K21430 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - GSDH TGS3_k127_2737533_0 314260.PB2503_09759 1.898e-138 444.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 TGS3_k127_2737533_1 1122137.AQXF01000001_gene3216 4.02e-35 143.0 COG0457@1|root,COG0457@2|Bacteria,1Q2R2@1224|Proteobacteria,2UJNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - TGS3_k127_2770515_11 1211114.ALIP01000069_gene313 2.973e-21 100.0 2ERUI@1|root,33JDR@2|Bacteria,1NP15@1224|Proteobacteria,1SH0N@1236|Gammaproteobacteria,1XB68@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - TGS3_k127_2770515_10 1247963.JPHU01000007_gene1662 1.84e-21 96.0 COG0762@1|root,COG0762@2|Bacteria 2|Bacteria D integral membrane protein yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02221 - - - - ko00000,ko02044 - - - YGGT TGS3_k127_2770515_12 46429.BV95_04082 8.609e-20 94.0 COG1872@1|root,COG1872@2|Bacteria 2|Bacteria I DUF167 MA20_25230 - - ko:K09131 - - - - ko00000 - - - DUF167 TGS3_k127_2770515_4 1411123.JQNH01000001_gene2750 1.674e-107 357.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C TGS3_k127_2770515_6 1280954.HPO_16485 2.392e-97 322.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2TQKR@28211|Alphaproteobacteria,43X2T@69657|Hyphomonadaceae 28211|Alphaproteobacteria G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim TGS3_k127_2770515_7 1333998.M2A_0152 4.335e-83 298.0 COG5360@1|root,COG5360@2|Bacteria,1MUJ4@1224|Proteobacteria,2TR5G@28211|Alphaproteobacteria,4BQ85@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Heparinase II/III-like protein MA20_25080 - - - - - - - - - - - Hepar_II_III TGS3_k127_2770515_3 1247963.JPHU01000002_gene2590 5.175e-156 503.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2TT4K@28211|Alphaproteobacteria 28211|Alphaproteobacteria GM Polysaccharide biosynthesis protein capD - - ko:K13013 - - - - ko00000,ko01005 - - - CoA_binding_3,Polysacc_synt_2 TGS3_k127_2770515_2 1244869.H261_21728 3.299e-223 702.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2TRMY@28211|Alphaproteobacteria,2JPE6@204441|Rhodospirillales 204441|Rhodospirillales F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS TGS3_k127_2770515_0 1161401.ASJA01000002_gene2539 0.0 1454.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,43X99@69657|Hyphomonadaceae 28211|Alphaproteobacteria E COG2902 NAD-specific glutamate dehydrogenase gdhB GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH TGS3_k127_2770515_9 1297865.APJD01000012_gene1317 1.985e-56 201.0 COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,2U962@28211|Alphaproteobacteria,3JYGA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Cupin superfamily (DUF985) MA20_39615 - - ko:K09705 - - - - ko00000 - - - Cupin_5 TGS3_k127_2770515_13 314254.OA2633_09859 4.669e-15 83.0 COG0457@1|root,COG0457@2|Bacteria,1RK4Q@1224|Proteobacteria,2UBBB@28211|Alphaproteobacteria,43Y4T@69657|Hyphomonadaceae 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_9 TGS3_k127_2770515_1 1247963.JPHU01000009_gene2359 8.398e-277 877.0 COG0642@1|root,COG2205@2|Bacteria,1MVY8@1224|Proteobacteria,2TS5B@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase divL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - HATPase_c,HisKA,PAS_7,PAS_8 TGS3_k127_2770515_5 394221.Mmar10_1851 5.043e-102 363.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2TRSN@28211|Alphaproteobacteria,43WWJ@69657|Hyphomonadaceae 28211|Alphaproteobacteria M protein involved in outer membrane biogenesis - - - ko:K07289 - - - - ko00000 - - - AsmA,AsmA_2 TGS3_k127_2770515_8 1280946.HY29_03950 1.06e-61 235.0 COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TQRF@28211|Alphaproteobacteria 28211|Alphaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins - - 3.4.13.22,3.4.16.4 ko:K01286,ko:K08641 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - Beta-lactamase TGS3_k127_2800308_2 237727.NAP1_05065 4.127e-94 319.0 COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,2TVY6@28211|Alphaproteobacteria,2K42C@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short TGS3_k127_2800308_0 1292034.OR37_02706 2.608e-170 543.0 COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,2TV1G@28211|Alphaproteobacteria,2KHUE@204458|Caulobacterales 204458|Caulobacterales S Saccharopine dehydrogenase NADP binding domain - - - - - - - - - - - - Sacchrp_dh_NADP TGS3_k127_2800308_3 1248917.ANFX01000014_gene1323 4.693e-34 152.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1N7YB@1224|Proteobacteria,2V7CZ@28211|Alphaproteobacteria,2K2SU@204457|Sphingomonadales 204457|Sphingomonadales S TIR domain - - - - - - - - - - - - TIR_2 TGS3_k127_2800308_1 1161401.ASJA01000005_gene2399 2.095e-129 419.0 COG4805@1|root,COG4805@2|Bacteria,1R84Q@1224|Proteobacteria,2TT6N@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 TGS3_k127_282558_2 1417296.U879_14120 6.263e-65 227.0 COG4424@1|root,COG4424@2|Bacteria,1N77D@1224|Proteobacteria,2TY6P@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 TGS3_k127_282558_5 1247963.JPHU01000016_gene1057 1.593e-35 143.0 2CFTD@1|root,32RKN@2|Bacteria,1N11N@1224|Proteobacteria,2UBTR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2937) - - - - - - - - - - - - DUF2937 TGS3_k127_282558_3 1247963.JPHU01000002_gene2677 2.28e-63 223.0 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2TS4E@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C TGS3_k127_282558_1 314260.PB2503_04297 6.25e-249 778.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2TRQN@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 TGS3_k127_282558_4 412597.AEPN01000005_gene1423 1.995e-38 152.0 COG2740@1|root,COG2740@2|Bacteria,1RHPR@1224|Proteobacteria,2U9RY@28211|Alphaproteobacteria,2PVA1@265|Paracoccus 28211|Alphaproteobacteria K Protein of unknown function (DUF448) MA20_23920 - - ko:K07742 - - - - ko00000 - - - DUF448,Ribosomal_L7Ae TGS3_k127_282558_0 1247963.JPHU01000002_gene2674 0.0 1052.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2TQMY@28211|Alphaproteobacteria 28211|Alphaproteobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc TGS3_k127_2840693_0 648757.Rvan_0310 5.955e-89 294.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2TS6C@28211|Alphaproteobacteria,3N677@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 TGS3_k127_2840693_4 1187851.A33M_4266 2.508e-22 98.0 2E3EN@1|root,32YDN@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4160) - - - - - - - - - - - - DUF4160 TGS3_k127_2840693_3 136993.KB900626_gene3973 8.39e-26 109.0 2EH09@1|root,33ASB@2|Bacteria,1QWA1@1224|Proteobacteria,2UMI7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2442) - - - - - - - - - - - - DUF2442 TGS3_k127_2840693_2 1280944.HY17_10900 3.715e-29 119.0 COG1262@1|root,COG4916@1|root,COG1262@2|Bacteria,COG4916@2|Bacteria,1NQ5K@1224|Proteobacteria,2U2VJ@28211|Alphaproteobacteria,43ZFH@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,Guanylate_cyc TGS3_k127_2848051_1 314260.PB2503_08649 2.932e-97 327.0 COG1652@1|root,COG1652@2|Bacteria,1MWMR@1224|Proteobacteria,2U7UH@28211|Alphaproteobacteria 28211|Alphaproteobacteria M protein containing LysM domain lysM - - - - - - - - - - - LysM TGS3_k127_2848051_2 314260.PB2503_08644 3.3e-64 225.0 COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2U5DP@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Belongs to the LOG family yvdD - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox TGS3_k127_2848051_0 1247963.JPHU01000001_gene1916 5.227e-108 356.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRCI@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX1 - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c TGS3_k127_2850036_6 394221.Mmar10_1812 8.574e-76 272.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,43WYB@69657|Hyphomonadaceae 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_14,TPR_16,TPR_19,TPR_8 TGS3_k127_2850036_1 1247963.JPHU01000015_gene1134 7.318e-103 340.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,2TV43@28211|Alphaproteobacteria 28211|Alphaproteobacteria O alkyl hydroperoxide reductase ahpC - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA TGS3_k127_2850036_4 1122613.ATUP01000001_gene1300 2.063e-85 293.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2TSUS@28211|Alphaproteobacteria,43X3W@69657|Hyphomonadaceae 28211|Alphaproteobacteria K Transcriptional regulator - - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate TGS3_k127_2850036_3 1247963.JPHU01000015_gene1139 9.525e-95 323.0 COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2TQJJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S permease - - - - - - - - - - - - AI-2E_transport TGS3_k127_2850036_5 402881.Plav_1564 6.308e-79 280.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,1JPZN@119043|Rhodobiaceae 28211|Alphaproteobacteria EH chorismate binding enzyme pabB - 2.6.1.85,4.1.3.27 ko:K01657,ko:K01665 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind TGS3_k127_2850036_7 1449065.JMLL01000013_gene2886 1.397e-66 233.0 COG0512@1|root,COG0512@2|Bacteria,1NWN9@1224|Proteobacteria,2TZDX@28211|Alphaproteobacteria,43RWK@69277|Phyllobacteriaceae 28211|Alphaproteobacteria EH Peptidase C26 - - 4.1.3.27 ko:K13503 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase TGS3_k127_2850036_9 1282876.BAOK01000002_gene576 2.63e-38 157.0 COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,2U9QU@28211|Alphaproteobacteria,4BS4N@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria EH Amino-transferase class IV - - 2.6.1.42,4.1.3.38 ko:K00826,ko:K02619 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R05553,R10991 RC00006,RC00036,RC01843,RC02148 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 TGS3_k127_2850036_2 1247963.JPHU01000009_gene2373 2.087e-102 347.0 COG0318@1|root,COG0318@2|Bacteria,1QA57@1224|Proteobacteria,2UB10@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ AMP-binding enzyme - - - - - - - - - - - - AMP-binding,AMP-binding_C TGS3_k127_2850036_12 314260.PB2503_05347 7.286e-25 109.0 COG4964@1|root,COG4964@2|Bacteria 2|Bacteria U Pilus formation protein N terminal region MA20_18400 - - ko:K02280 - - - - ko00000,ko02035,ko02044 - - - BON,Secretin,T2SS-T3SS_pil_N TGS3_k127_2850036_13 314260.PB2503_05352 2.76e-15 86.0 COG0664@1|root,COG0664@2|Bacteria 2|Bacteria T cyclic nucleotide binding - - 1.8.1.9 ko:K00384,ko:K07001,ko:K10914 ko00450,ko02020,ko02024,ko02025,ko02026,ko05111,map00450,map02020,map02024,map02025,map02026,map05111 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000,ko03000 - - - HTH_Crp_2,cNMP_binding TGS3_k127_2850036_14 314254.OA2633_13155 6.878e-13 70.0 COG3847@1|root,COG3847@2|Bacteria,1NGVU@1224|Proteobacteria,2UJE8@28211|Alphaproteobacteria,43YY0@69657|Hyphomonadaceae 28211|Alphaproteobacteria U Flp/Fap pilin component MA20_03885 - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - Flp_Fap TGS3_k127_2850036_11 588932.JHOF01000024_gene95 1.18e-27 120.0 COG4960@1|root,COG4960@2|Bacteria,1RAYG@1224|Proteobacteria,2TSVX@28211|Alphaproteobacteria,2KH3I@204458|Caulobacterales 204458|Caulobacterales OU peptidase - - 3.4.23.43 ko:K02278 - - - - ko00000,ko01000,ko02035,ko02044 - - - Peptidase_A24 TGS3_k127_2850036_8 316057.RPD_3519 6.367e-42 164.0 COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,2TTPE@28211|Alphaproteobacteria,3JTGM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U pilus assembly protein CpaB cpaB - - ko:K02279 - - - - ko00000,ko02035,ko02044 - - - RcpC,SAF TGS3_k127_2850036_0 1282876.BAOK01000001_gene3382 1.157e-139 460.0 COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,2TRNN@28211|Alphaproteobacteria,4BQ1G@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria U Pilus formation protein N terminal region cpaC - - ko:K02280 - - - - ko00000,ko02035,ko02044 - - - BON,Secretin,T2SS-T3SS_pil_N TGS3_k127_2850036_10 402881.Plav_0234 2.09e-31 133.0 COG5461@1|root,COG5461@2|Bacteria,1MWWE@1224|Proteobacteria,2TU2Q@28211|Alphaproteobacteria,1JPGN@119043|Rhodobiaceae 28211|Alphaproteobacteria N Pilus biogenesis CpaD protein (pilus_cpaD) cpaD - - ko:K02281 - - - - ko00000,ko02035,ko02044 - - - Pilus_CpaD TGS3_k127_2851680_0 314260.PB2503_09619 1.388e-313 972.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2TQZV@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim TGS3_k127_2851680_2 118161.KB235922_gene5337 3.702e-15 83.0 COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1GC8T@1117|Cyanobacteria 1117|Cyanobacteria Q Lactonase, 7-bladed beta-propeller - - - - - - - - - - - - HemolysinCabind,Lactonase TGS3_k127_2851680_1 1449049.JONW01000005_gene1661 4.372e-17 90.0 2EPBG@1|root,33GY8@2|Bacteria,1NQ0N@1224|Proteobacteria,2UM1M@28211|Alphaproteobacteria,2KHUU@204458|Caulobacterales 204458|Caulobacterales S Protein of unknown function (DUF1353) - - - - - - - - - - - - DUF1353 TGS3_k127_2853852_0 1479238.JQMZ01000001_gene91 8.817e-171 552.0 COG2352@1|root,COG2352@2|Bacteria,1PUW3@1224|Proteobacteria,2V6E4@28211|Alphaproteobacteria,43WWC@69657|Hyphomonadaceae 28211|Alphaproteobacteria C Phosphoenolpyruvate carboxylase - - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase TGS3_k127_2853852_4 685778.AORL01000022_gene1299 1.511e-74 255.0 COG1435@1|root,COG1435@2|Bacteria,1NJR4@1224|Proteobacteria,2TV1A@28211|Alphaproteobacteria,2K1CD@204457|Sphingomonadales 204457|Sphingomonadales F thymidine kinase tdk - 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK TGS3_k127_2853852_2 1247963.JPHU01000002_gene2543 1.305e-108 359.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2TUF2@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase TGS3_k127_2853852_1 1205753.A989_15617 3.973e-116 399.0 COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,1SU7S@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyl transferase family group 2 - - - ko:K20327 ko02024,map02024 - - - ko00000,ko00001,ko01003 - GT2 - Glyco_tranf_2_3,Glyco_trans_2_3,T2SSE_N TGS3_k127_2853852_5 1120983.KB894570_gene1658 4.83e-18 94.0 2BCV0@1|root,326FP@2|Bacteria,1MYXP@1224|Proteobacteria,2U5PU@28211|Alphaproteobacteria,1JPI0@119043|Rhodobiaceae 28211|Alphaproteobacteria - - - - - ko:K20326 ko02024,map02024 - - - ko00000,ko00001 - - - Phenol_MetA_deg TGS3_k127_2853852_3 314260.PB2503_04032 1.386e-85 286.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C TGS3_k127_2888819_2 1161401.ASJA01000003_gene2762 5.171e-59 209.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2TQN6@28211|Alphaproteobacteria,43WSW@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 TGS3_k127_2888819_4 89187.ISM_11340 4.461e-33 138.0 COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,2U33F@28211|Alphaproteobacteria,46P5Q@74030|Roseovarius 28211|Alphaproteobacteria S Protein of unknown function (DUF1223) MA20_43790 - - - - - - - - - - - DUF1223 TGS3_k127_2888819_0 394221.Mmar10_1630 4.669e-161 514.0 COG3396@1|root,COG3396@2|Bacteria,1QYPN@1224|Proteobacteria,2TXUS@28211|Alphaproteobacteria,44152@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Long-chain fatty aldehyde decarbonylase - - - - - - - - - - - - AurF TGS3_k127_2888819_1 1292034.OR37_01708 3.604e-63 219.0 COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2U6ZS@28211|Alphaproteobacteria,2KGG1@204458|Caulobacterales 204458|Caulobacterales K Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR TGS3_k127_2888819_6 1054213.HMPREF9946_04738 4.045e-23 106.0 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2UF5C@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10 TGS3_k127_2888819_5 1131814.JAFO01000001_gene4945 3.423e-27 119.0 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2TTM2@28211|Alphaproteobacteria,3EZ6T@335928|Xanthobacteraceae 28211|Alphaproteobacteria O Glycoprotease family yeaZ - 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 TGS3_k127_2888819_3 1244869.H261_13529 1.622e-57 202.0 COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,2U5B0@28211|Alphaproteobacteria,2JRTH@204441|Rhodospirillales 204441|Rhodospirillales C NADH dehydrogenase NAD(P)H nitroreductase rutE - - ko:K09019 ko00240,ko01100,map00240,map01100 - R09289 RC00087 ko00000,ko00001,ko01000 - - - Nitroreductase TGS3_k127_2907847_5 983917.RGE_18190 0.0009146 51.0 COG3409@1|root,COG5549@1|root,COG3409@2|Bacteria,COG5549@2|Bacteria,1QWB0@1224|Proteobacteria 1224|Proteobacteria O Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - Peptidase_M10,Peptidase_M10_C TGS3_k127_2907847_0 1247963.JPHU01000003_gene1370 9.41e-208 655.0 COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2TSK3@28211|Alphaproteobacteria 28211|Alphaproteobacteria I acyl-CoA dehydrogenase MA20_31035 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N TGS3_k127_2907847_3 1333998.M2A_0660 1.881e-48 180.0 COG5331@1|root,COG5331@2|Bacteria,1N0MD@1224|Proteobacteria,2UEP8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - MAPEG TGS3_k127_2907847_4 1185652.USDA257_c32810 6.196e-48 174.0 COG3450@1|root,COG3450@2|Bacteria,1N07J@1224|Proteobacteria,2UCQ9@28211|Alphaproteobacteria,4BFH5@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF861) - - - ko:K06995 - - - - ko00000 - - - Cupin_3 TGS3_k127_2907847_2 1110502.TMO_1455 8.299e-69 244.0 COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria,2TRRV@28211|Alphaproteobacteria,2JR17@204441|Rhodospirillales 204441|Rhodospirillales G Phosphoenolpyruvate phosphomutase - - - - - - - - - - - - PEP_mutase TGS3_k127_2907847_1 1247963.JPHU01000001_gene2059 1.04e-136 440.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2TR9Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria K RNA polymerase sigma rpoH - - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 TGS3_k127_2919406_2 1211115.ALIQ01000145_gene1032 1.764e-41 153.0 COG0583@1|root,COG0583@2|Bacteria,1MU2E@1224|Proteobacteria,2TUNU@28211|Alphaproteobacteria,3NCF2@45404|Beijerinckiaceae 28211|Alphaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate TGS3_k127_2919406_0 1211115.ALIQ01000145_gene1031 7.068e-122 395.0 COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,2TUSA@28211|Alphaproteobacteria,3NCQZ@45404|Beijerinckiaceae 28211|Alphaproteobacteria S KR domain - - - - - - - - - - - - adh_short TGS3_k127_2919406_1 1211115.ALIQ01000145_gene1030 1.665e-62 220.0 COG0599@1|root,COG0599@2|Bacteria,1PFRN@1224|Proteobacteria,2V8R2@28211|Alphaproteobacteria,3NCUJ@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Carboxymuconolactone decarboxylase family - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD TGS3_k127_2919406_6 585423.KR49_11535 1.44e-08 68.0 COG1388@1|root,COG1388@2|Bacteria,1GBSW@1117|Cyanobacteria,1GYFF@1129|Synechococcus 1117|Cyanobacteria M COG1388 FOG LysM repeat - - - - - - - - - - - - LysM TGS3_k127_2919406_4 757424.Hsero_1196 2.653e-20 91.0 COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2VW2V@28216|Betaproteobacteria,4750Y@75682|Oxalobacteraceae 28216|Betaproteobacteria S Belongs to the UPF0337 (CsbD) family - - - - - - - - - - - - CsbD TGS3_k127_2919406_3 717785.HYPMC_3307 1.278e-29 134.0 COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2TVPN@28211|Alphaproteobacteria,3N9GN@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport TGS3_k127_2936425_2 1545915.JROG01000007_gene3015 2.719e-28 118.0 COG0640@1|root,COG0640@2|Bacteria,1N3H4@1224|Proteobacteria,2UCAF@28211|Alphaproteobacteria,2K5XK@204457|Sphingomonadales 204457|Sphingomonadales K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_5 TGS3_k127_2936425_1 1247963.JPHU01000006_gene121 2.806e-94 314.0 COG0288@1|root,COG0288@2|Bacteria,1MV1U@1224|Proteobacteria,2VEYE@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Reversible hydration of carbon dioxide cynT - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA TGS3_k127_2936425_0 1280952.HJA_06767 1.729e-228 720.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,2U0W9@28211|Alphaproteobacteria,43ZC8@69657|Hyphomonadaceae 28211|Alphaproteobacteria U COG0659 Sulfate permease and related transporters (MFS superfamily) - - - - - - - - - - - - STAS,Sulfate_transp TGS3_k127_2940404_2 190650.CC_3151 1.07e-11 76.0 COG4219@1|root,COG4219@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Peptidase_M56,Plug,TonB_C TGS3_k127_2940404_0 1479238.JQMZ01000001_gene1380 1.933e-24 107.0 COG3682@1|root,COG3682@2|Bacteria,1MZU3@1224|Proteobacteria,2UIN1@28211|Alphaproteobacteria,43Y9J@69657|Hyphomonadaceae 28211|Alphaproteobacteria K Transcriptional regulator - - - - - - - - - - - - Penicillinase_R TGS3_k127_2940404_1 391593.RCCS2_09989 4.256e-16 80.0 COG1247@1|root,COG1247@2|Bacteria,1RC8Z@1224|Proteobacteria,2UA7B@28211|Alphaproteobacteria,2P3BH@2433|Roseobacter 28211|Alphaproteobacteria M COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 TGS3_k127_2943567_3 1123072.AUDH01000027_gene1843 1.194e-22 103.0 COG0593@1|root,COG0593@2|Bacteria,1N4PG@1224|Proteobacteria,2U96K@28211|Alphaproteobacteria,2JS7B@204441|Rhodospirillales 204441|Rhodospirillales L COG0593 ATPase involved in DNA replication initiation - - - - - - - - - - - - Bac_DnaA TGS3_k127_2943567_0 69395.JQLZ01000008_gene2579 1.537e-292 915.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2TRBP@28211|Alphaproteobacteria,2KFTC@204458|Caulobacterales 204458|Caulobacterales H Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N TGS3_k127_2943567_2 1121033.AUCF01000006_gene4276 3.014e-107 366.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TR1W@28211|Alphaproteobacteria,2JQ21@204441|Rhodospirillales 204441|Rhodospirillales FP Ppx/GppA phosphatase family - - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA TGS3_k127_2943567_1 314260.PB2503_10199 3.488e-238 752.0 COG3064@1|root,COG3243@1|root,COG3064@2|Bacteria,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TR7S@28211|Alphaproteobacteria 28211|Alphaproteobacteria I poly-beta-hydroxybutyrate polymerase phbC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1,PhaC_N TGS3_k127_2978074_1 1247963.JPHU01000003_gene1201 1.618e-72 254.0 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,2TWE1@28211|Alphaproteobacteria 28211|Alphaproteobacteria O peptidase - - - - - - - - - - - - Peptidase_M48 TGS3_k127_2978074_0 1247963.JPHU01000012_gene921 3.323e-101 332.0 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2TR3M@28211|Alphaproteobacteria 28211|Alphaproteobacteria L HNH endonuclease MA20_20605 - - - - - - - - - - - HNH,HNH_5 TGS3_k127_2978074_3 1247963.JPHU01000012_gene919 1.519e-58 211.0 COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2TVJ7@28211|Alphaproteobacteria 28211|Alphaproteobacteria L 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase alkA - 3.2.2.21 ko:K01247 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD TGS3_k127_2978074_2 1331060.RLDS_20710 3.687e-64 224.0 COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,2TRPT@28211|Alphaproteobacteria,2K1IW@204457|Sphingomonadales 204457|Sphingomonadales H glutamate--cysteine ligase - - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - GCS2 TGS3_k127_297924_1 1280950.HJO_16827 9.481e-28 128.0 COG0457@1|root,COG1262@1|root,COG0457@2|Bacteria,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,2U2VJ@28211|Alphaproteobacteria,43ZFH@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,Guanylate_cyc,TIR_2 TGS3_k127_297924_0 314260.PB2503_02957 4.502e-210 668.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2TQU6@28211|Alphaproteobacteria 28211|Alphaproteobacteria O ATPase with chaperone activity comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C TGS3_k127_2982868_6 1381123.AYOD01000054_gene433 2.168e-48 175.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria,43J34@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Cysteine synthase cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP TGS3_k127_2982868_9 1004785.AMBLS11_13455 3.614e-08 66.0 COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,1R3YH@1224|Proteobacteria,1RX87@1236|Gammaproteobacteria,465U0@72275|Alteromonadaceae 1236|Gammaproteobacteria U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - Peptidase_M56,TonB_C TGS3_k127_2982868_1 1535422.ND16A_1887 1.467e-188 601.0 COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,1RQ1A@1236|Gammaproteobacteria,2Q6Q9@267889|Colwelliaceae 1236|Gammaproteobacteria M PFAM membrane bound O-acyl transferase MBOAT family protein patA - - - - - - - - - - - MBOAT TGS3_k127_2982868_5 1123073.KB899241_gene2664 2.383e-64 233.0 2BSEF@1|root,32MGE@2|Bacteria,1N9VN@1224|Proteobacteria,1SG8G@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_2982868_7 1384054.N790_10665 1.464e-32 139.0 COG0457@1|root,COG0457@2|Bacteria,1NPAW@1224|Proteobacteria,1SHZA@1236|Gammaproteobacteria,1X9FY@135614|Xanthomonadales 135614|Xanthomonadales S Tetratricopeptide repeats - - - - - - - - - - - - TPR_16 TGS3_k127_2982868_4 448385.sce5713 4.112e-116 392.0 COG1222@1|root,COG1222@2|Bacteria,1QVRV@1224|Proteobacteria 1224|Proteobacteria O Belongs to the AAA ATPase family - - - - - - - - - - - - AAA TGS3_k127_2982868_2 715226.ABI_34590 1.234e-138 460.0 COG3279@1|root,COG3279@2|Bacteria,1Q4EQ@1224|Proteobacteria,2U46F@28211|Alphaproteobacteria,2KGTF@204458|Caulobacterales 204458|Caulobacterales KT LytTr DNA-binding domain - - - - - - - - - - - - LytTR TGS3_k127_2982868_0 1282360.ABAC460_11140 1.168e-210 664.0 COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,2U29F@28211|Alphaproteobacteria,2KFNA@204458|Caulobacterales 204458|Caulobacterales S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 TGS3_k127_2982868_10 82654.Pse7367_1130 0.0003248 47.0 2DQ2Q@1|root,334I5@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - TGS3_k127_2982868_3 314260.PB2503_06912 6.477e-137 443.0 COG0596@1|root,COG0596@2|Bacteria,1MUSF@1224|Proteobacteria,2TSK5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Alpha beta hydrolase dhmA - 3.8.1.5 ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 - - - Abhydrolase_1 TGS3_k127_2982868_8 1050202.KB913024_gene3299 9.151e-16 91.0 COG5479@1|root,COG5479@2|Bacteria,2HFYS@201174|Actinobacteria,40A1Y@622450|Actinopolysporales 201174|Actinobacteria M LGFP repeat - - - - - - - - - - - - LGFP TGS3_k127_29939_3 1280950.HJO_06882 1.234e-85 290.0 COG2133@1|root,COG2133@2|Bacteria,1R86D@1224|Proteobacteria,2U1Z1@28211|Alphaproteobacteria,43ZJQ@69657|Hyphomonadaceae 28211|Alphaproteobacteria G Cadherin repeats. - - - - - - - - - - - - Cadherin,GSDH TGS3_k127_29939_5 1280941.HY2_15250 1.446e-49 192.0 COG0494@1|root,COG0494@2|Bacteria,1NTFG@1224|Proteobacteria,2U0I4@28211|Alphaproteobacteria,43YXJ@69657|Hyphomonadaceae 28211|Alphaproteobacteria L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes MA20_35615 - - - - - - - - - - - NUDIX TGS3_k127_29939_6 314225.ELI_07040 1.167e-15 82.0 2DRDD@1|root,33BAA@2|Bacteria,1NJN6@1224|Proteobacteria,2UYFX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_29939_4 84531.JMTZ01000003_gene2339 2.887e-80 276.0 COG0730@1|root,COG0730@2|Bacteria,1R6MR@1224|Proteobacteria,1S0QW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE TGS3_k127_29939_0 378806.STAUR_8186 7.278e-139 461.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,43BBS@68525|delta/epsilon subdivisions,2X6QY@28221|Deltaproteobacteria,2YU79@29|Myxococcales 28221|Deltaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 TGS3_k127_29939_2 1120953.AUBH01000001_gene840 6.473e-98 325.0 COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,1S0J9@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 TGS3_k127_29939_1 1123073.KB899242_gene1451 4.8e-121 395.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1RPIW@1236|Gammaproteobacteria,1X5RA@135614|Xanthomonadales 135614|Xanthomonadales Q Amidohydrolase family - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 TGS3_k127_2997621_0 1247963.JPHU01000012_gene917 5.507e-143 460.0 COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,2TRPT@28211|Alphaproteobacteria 28211|Alphaproteobacteria H glutamate--cysteine ligase gshA - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - GCS2 TGS3_k127_2997621_2 394221.Mmar10_2241 2.191e-72 252.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2TS0N@28211|Alphaproteobacteria,43W5T@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA TGS3_k127_2997621_1 1122218.KB893654_gene2235 2.002e-107 356.0 COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2TT3I@28211|Alphaproteobacteria,1JSUI@119045|Methylobacteriaceae 28211|Alphaproteobacteria H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate ubiA - 2.5.1.39 ko:K03179,ko:K06125 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117,M00128 R05000,R05615,R05616,R07273 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA TGS3_k127_2997621_3 69042.WH5701_15106 1.468e-60 213.0 COG0229@1|root,COG0229@2|Bacteria,1G60F@1117|Cyanobacteria,1GZZ9@1129|Synechococcus 1117|Cyanobacteria O COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase - - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR TGS3_k127_2997621_4 1282876.BAOK01000001_gene3411 8.05e-33 128.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2TRDY@28211|Alphaproteobacteria,4BPBN@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria GM COG0451 Nucleoside-diphosphate-sugar epimerases - - - - - - - - - - - - Epimerase TGS3_k127_2998993_0 1197906.CAJQ02000034_gene2833 2.421e-186 610.0 COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,2TVX5@28211|Alphaproteobacteria,3JWD7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P TonB dependent receptor - - - ko:K16090 - - - - ko00000,ko02000 1.B.14.1.11 - - Plug,TonB_dep_Rec TGS3_k127_2998993_1 1122137.AQXF01000005_gene1263 3.805e-106 347.0 COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TQKN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM Prokaryotic protein of MA20_22960 - - - - - - - - - - - BKACE TGS3_k127_3023075_0 1247963.JPHU01000008_gene2784 1.33e-132 450.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TWEB@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K07716 ko02020,ko04112,map02020,map04112 M00511 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_7 TGS3_k127_3023075_1 1247963.JPHU01000008_gene2785 5.044e-118 394.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria 28211|Alphaproteobacteria E aminopeptidase N pepN GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 TGS3_k127_3027050_0 1121123.AUAO01000003_gene2088 3.982e-99 328.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria,2KFS1@204458|Caulobacterales 204458|Caulobacterales E PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein - - 4.4.1.1,4.4.1.11 ko:K01758,ko:K01761 ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230 M00338 R00654,R00782,R01001,R02408,R04770,R04930,R09366 RC00056,RC00069,RC00196,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Cys_Met_Meta_PP TGS3_k127_3027050_1 1247963.JPHU01000008_gene2813 2.977e-85 291.0 COG0596@1|root,COG0596@2|Bacteria,1N5ZI@1224|Proteobacteria,2TS7X@28211|Alphaproteobacteria 28211|Alphaproteobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - 2.7.10.2,3.3.2.9 ko:K01253,ko:K08253 ko00980,ko04976,ko05204,map00980,map04976,map05204 - R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443 RC01447,RC01728,RC01764,RC02528 ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 TGS3_k127_3032683_2 1122613.ATUP01000001_gene2382 8.059e-150 488.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2TQPS@28211|Alphaproteobacteria,43W87@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3 TGS3_k127_3032683_4 745310.G432_01500 5.661e-52 191.0 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2U79T@28211|Alphaproteobacteria,2K1ZP@204457|Sphingomonadales 204457|Sphingomonadales S Phosphoglycolate phosphatase gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 TGS3_k127_3032683_7 1247963.JPHU01000010_gene2246 1.935e-20 93.0 2FJXC@1|root,34BJT@2|Bacteria,1P3X9@1224|Proteobacteria,2UVIQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_3032683_6 1247963.JPHU01000010_gene2245 1.116e-44 170.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding dicA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K22300 - - - - ko00000,ko03000 - - - HTH_19,HTH_3,Peptidase_S24 TGS3_k127_3032683_1 1134912.AJTV01000030_gene2094 2.01e-171 571.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TWN3@28211|Alphaproteobacteria,36XKK@31993|Methylocystaceae 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Hpt,Response_reg TGS3_k127_3032683_3 1123229.AUBC01000007_gene250 7.386e-65 242.0 COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria,3JSG2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_7 TGS3_k127_3032683_0 1537715.JQFJ01000002_gene1179 2.883e-191 634.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1R479@1224|Proteobacteria,2TV3V@28211|Alphaproteobacteria,2K147@204457|Sphingomonadales 204457|Sphingomonadales P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec TGS3_k127_3032683_5 394221.Mmar10_0860 3.532e-46 177.0 COG0189@1|root,COG0189@2|Bacteria,1RE49@1224|Proteobacteria,2U7EY@28211|Alphaproteobacteria,43WSM@69657|Hyphomonadaceae 28211|Alphaproteobacteria HJ ligase activity - - - - - - - - - - - - - TGS3_k127_3043267_3 1121920.AUAU01000001_gene2168 9.709e-68 246.0 COG2519@1|root,COG2519@2|Bacteria,3Y5T2@57723|Acidobacteria 57723|Acidobacteria J Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - - - - - - - - - - Methyltransf_31 TGS3_k127_3043267_4 991905.SL003B_2078 1.636e-61 222.0 COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2TRB2@28211|Alphaproteobacteria,4BQ7Y@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the complex I subunit 6 family nuoJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 TGS3_k127_3043267_5 1297863.APJF01000008_gene653 4.26e-41 155.0 COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2U93P@28211|Alphaproteobacteria,3JZE4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 TGS3_k127_3043267_0 1247963.JPHU01000008_gene2789 1.784e-262 826.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TQSS@28211|Alphaproteobacteria 28211|Alphaproteobacteria CP NADH ubiquinone oxidoreductase subunit 5 (chain L) multisubunit Na H antiporter, MnhA subunit nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADH5_C,Proton_antipo_M,Proton_antipo_N TGS3_k127_3043267_1 1247963.JPHU01000008_gene2790 7.605e-212 672.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria 28211|Alphaproteobacteria C NADH ubiquinone oxidoreductase subunit 4 (chain M) nuoM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M TGS3_k127_3043267_2 1247963.JPHU01000008_gene2791 2.187e-160 518.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2TQMX@28211|Alphaproteobacteria 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M TGS3_k127_3043267_6 366602.Caul_2818 1.914e-37 149.0 COG0340@1|root,COG0340@2|Bacteria,1MWCC@1224|Proteobacteria,2TS82@28211|Alphaproteobacteria,2KFF4@204458|Caulobacterales 204458|Caulobacterales H biotin lipoate A B protein ligase - - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB TGS3_k127_30484_0 1247963.JPHU01000004_gene528 1.999e-218 686.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains tacA GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - - - - - - - - - - HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat TGS3_k127_30484_3 1282360.ABAC460_19210 1.949e-13 75.0 COG3668@1|root,COG3668@2|Bacteria 2|Bacteria D Plasmid stabilization system - - - - - - - - - - - - ParE_toxin TGS3_k127_30484_2 1333998.M2A_2163 4.045e-27 114.0 COG3750@1|root,COG3750@2|Bacteria,1N77J@1224|Proteobacteria,2UFX6@28211|Alphaproteobacteria,4BQRC@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2312) - - - - - - - - - - - - DUF2312 TGS3_k127_30484_1 316058.RPB_1516 1.947e-158 506.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2TQZU@28211|Alphaproteobacteria,3JTPJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS TGS3_k127_3054509_0 1121923.GPUN_0177 1.92e-149 481.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,464A5@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM TGS3_k127_3054509_1 1128912.GMES_1516 7.188e-114 377.0 COG1638@1|root,COG1638@2|Bacteria,1NJX4@1224|Proteobacteria,1RQF6@1236|Gammaproteobacteria,46CN1@72275|Alteromonadaceae 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP TGS3_k127_3057391_3 1205680.CAKO01000040_gene909 1.478e-11 64.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2TSKQ@28211|Alphaproteobacteria,2JQRZ@204441|Rhodospirillales 204441|Rhodospirillales F Belongs to the phosphoglycerate kinase family pgk - 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK TGS3_k127_3057391_4 1297570.MESS4_830020 0.0001254 50.0 COG3631@1|root,COG3631@2|Bacteria 2|Bacteria S light absorption - - - ko:K06893 - - - - ko00000 - - - SnoaL_2 TGS3_k127_3057391_0 1247963.JPHU01000001_gene1849 2.724e-160 511.0 COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,2TSIV@28211|Alphaproteobacteria 28211|Alphaproteobacteria G fructose-bisphosphate aldolase fbaB - 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 - - - Glycolytic TGS3_k127_3057391_2 69395.JQLZ01000004_gene881 8.17e-48 175.0 COG3824@1|root,COG3824@2|Bacteria,1N18M@1224|Proteobacteria,2UBUK@28211|Alphaproteobacteria,2KGNW@204458|Caulobacterales 204458|Caulobacterales S Zincin-like metallopeptidase - - - - - - - - - - - - Zincin_1 TGS3_k127_3057391_1 1237149.C900_03398 5.293e-48 178.0 COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,47NMR@768503|Cytophagia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase TGS3_k127_313474_1 237727.NAP1_02950 1.144e-33 136.0 COG0637@1|root,COG0637@2|Bacteria,1NSPA@1224|Proteobacteria,2U0W3@28211|Alphaproteobacteria,2K05N@204457|Sphingomonadales 204457|Sphingomonadales S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 TGS3_k127_313474_0 402881.Plav_2916 6.7e-316 980.0 COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2TR9G@28211|Alphaproteobacteria,1JNE9@119043|Rhodobiaceae 28211|Alphaproteobacteria C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase TGS3_k127_3183355_1 1247963.JPHU01000008_gene2823 8.414e-77 268.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2TST5@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0530 Ca2 Na antiporter - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex TGS3_k127_3183355_2 1247963.JPHU01000008_gene2822 1.146e-63 230.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2TR0A@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ptr1 - - - - - - - - - - - adh_short,adh_short_C2 TGS3_k127_3183355_4 1121116.KB894769_gene1279 4.874e-18 92.0 COG1539@1|root,COG1539@2|Bacteria,1MY5Q@1224|Proteobacteria,2VRBR@28216|Betaproteobacteria,4AEPZ@80864|Comamonadaceae 28216|Betaproteobacteria H Dihydroneopterin aldolase folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB TGS3_k127_3183355_3 1247963.JPHU01000008_gene2820 3.245e-37 143.0 COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,2UI16@28211|Alphaproteobacteria 28211|Alphaproteobacteria H 6-pyruvoyl tetrahydropterin synthase - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS TGS3_k127_3183355_5 1278073.MYSTI_02758 1.061e-05 54.0 2BRFY@1|root,32KEU@2|Bacteria,1Q68E@1224|Proteobacteria,432KS@68525|delta/epsilon subdivisions,2WXZD@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Protein of unknown function (DUF3592) - - - - - - - - - - - - DUF3592 TGS3_k127_3183355_0 314260.PB2503_08409 9.456e-110 361.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria 28211|Alphaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N TGS3_k127_319122_2 573065.Astex_0582 1.394e-30 130.0 COG3391@1|root,COG3391@2|Bacteria,1NC58@1224|Proteobacteria,2UFDR@28211|Alphaproteobacteria,2KH9D@204458|Caulobacterales 204458|Caulobacterales S amine dehydrogenase activity - - - - - - - - - - - - TPR_19 TGS3_k127_319122_1 1112212.JH584235_gene1266 1.776e-48 181.0 COG3751@1|root,COG3751@2|Bacteria,1N8FI@1224|Proteobacteria,2UZ3N@28211|Alphaproteobacteria,2K19K@204457|Sphingomonadales 204457|Sphingomonadales O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - - TGS3_k127_319122_0 1187851.A33M_3950 1.417e-135 441.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2TRUB@28211|Alphaproteobacteria,3FCGT@34008|Rhodovulum 28211|Alphaproteobacteria L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon TGS3_k127_3193395_1 1385515.N791_01205 1.219e-110 362.0 COG1028@1|root,COG1028@2|Bacteria,1MUPX@1224|Proteobacteria,1RRW3@1236|Gammaproteobacteria,1X55U@135614|Xanthomonadales 135614|Xanthomonadales IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 TGS3_k127_3193395_3 1112212.JH584235_gene1266 5.098e-47 178.0 COG3751@1|root,COG3751@2|Bacteria,1N8FI@1224|Proteobacteria,2UZ3N@28211|Alphaproteobacteria,2K19K@204457|Sphingomonadales 204457|Sphingomonadales O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - - TGS3_k127_3193395_0 76114.ebA4662 1.631e-122 400.0 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2VIUW@28216|Betaproteobacteria,2KUNG@206389|Rhodocyclales 206389|Rhodocyclales E HMGL-like hmgL - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like TGS3_k127_3193395_2 1280952.HJA_07217 3.214e-63 221.0 COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,2U5BB@28211|Alphaproteobacteria,43ZV4@69657|Hyphomonadaceae 28211|Alphaproteobacteria L Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp TGS3_k127_3193395_4 582744.Msip34_1119 2.726e-05 49.0 29A26@1|root,2ZX3K@2|Bacteria,1RFE8@1224|Proteobacteria,2VRJJ@28216|Betaproteobacteria,2KMRG@206350|Nitrosomonadales 206350|Nitrosomonadales - - - - - - - - - - - - - - - TGS3_k127_3194879_5 288000.BBta_1009 3.203e-13 74.0 COG1215@1|root,COG1215@2|Bacteria,1PU38@1224|Proteobacteria,2U5E7@28211|Alphaproteobacteria,3JYSY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Glycosyl transferase family group 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glyco_trans_2_3 TGS3_k127_3194879_0 1265490.JHVY01000006_gene1789 2.313e-105 356.0 COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,1S0IX@1236|Gammaproteobacteria 1236|Gammaproteobacteria M glycosyl transferase group 1 - - - - - - - - - - - - Glycos_transf_1 TGS3_k127_3194879_4 1215114.BBIU01000002_gene265 8.937e-32 144.0 COG1215@1|root,COG1215@2|Bacteria,1QUG1@1224|Proteobacteria,1RZH7@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyl Transferase - - - - - - - - - - - - Glycos_transf_2 TGS3_k127_3194879_2 1101195.Meth11DRAFT_1105 5.534e-87 314.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VIK1@28216|Betaproteobacteria,2KNQ7@206350|Nitrosomonadales 206350|Nitrosomonadales U Viral (Superfamily 1) RNA helicase - - - - - - - - - - - - AAA_22 TGS3_k127_3194879_1 1165096.ARWF01000001_gene451 1.815e-98 352.0 COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,2WA1P@28216|Betaproteobacteria,2KNI0@206350|Nitrosomonadales 206350|Nitrosomonadales S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19 TGS3_k127_3194879_3 316055.RPE_1096 4.809e-42 164.0 COG1366@1|root,COG1922@1|root,COG1366@2|Bacteria,COG1922@2|Bacteria,1N1HD@1224|Proteobacteria,2TSBS@28211|Alphaproteobacteria,3JTQA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Belongs to the glycosyltransferase 26 family - - 2.4.1.187 ko:K05946 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003 - GT26 - Glyco_tran_WecB,STAS_2 TGS3_k127_3197651_5 1247963.JPHU01000001_gene1827 6.734e-25 107.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2TS37@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Transferase kdtA - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_N TGS3_k127_3197651_3 414684.RC1_3613 5.693e-63 228.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2TTZ4@28211|Alphaproteobacteria,2JPX7@204441|Rhodospirillales 204441|Rhodospirillales M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK TGS3_k127_3197651_1 1247963.JPHU01000001_gene1829 2.741e-91 310.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2TS2H@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Acyl-transferase msbB - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans TGS3_k127_3197651_4 551275.KB899545_gene2741 1.13e-45 171.0 COG0500@1|root,COG2226@2|Bacteria,1RFR5@1224|Proteobacteria,2U7RB@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 TGS3_k127_3197651_0 1123060.JONP01000028_gene3692 8.979e-94 313.0 COG1215@1|root,COG1215@2|Bacteria,1QWIM@1224|Proteobacteria,2TUF5@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Glycosyl transferase family 21 - - - - - - - - - - - - Glycos_transf_2 TGS3_k127_3197651_2 1161401.ASJA01000014_gene1063 5.408e-69 239.0 COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2TTQZ@28211|Alphaproteobacteria,43XK1@69657|Hyphomonadaceae 28211|Alphaproteobacteria O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N,GST_N_2,GST_N_3 TGS3_k127_3214536_3 1123503.KB908056_gene1290 7.131e-43 166.0 COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,2TR4F@28211|Alphaproteobacteria,2KFGT@204458|Caulobacterales 204458|Caulobacterales N FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliM - - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C TGS3_k127_3214536_7 1279038.KB907348_gene3076 0.0002279 49.0 2CHDB@1|root,32S5T@2|Bacteria,1N0D8@1224|Proteobacteria,2UCVM@28211|Alphaproteobacteria,2JTID@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - TGS3_k127_3214536_5 1177928.TH2_10419 1.218e-16 87.0 COG3334@1|root,COG3334@2|Bacteria,1RKF6@1224|Proteobacteria,2TRR1@28211|Alphaproteobacteria,2JSTD@204441|Rhodospirillales 204441|Rhodospirillales S PFAM MgtE intracellular - - - - - - - - - - - - MgtE_N TGS3_k127_3214536_4 441620.Mpop_0500 6.712e-23 114.0 COG0457@1|root,COG3064@1|root,COG0457@2|Bacteria,COG3064@2|Bacteria,1N09H@1224|Proteobacteria,2TSKT@28211|Alphaproteobacteria,1JRGW@119045|Methylobacteriaceae 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - TGS3_k127_3214536_1 316055.RPE_2960 4.86e-72 258.0 COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,2TU9T@28211|Alphaproteobacteria,3JRRT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Diguanylate cyclase MA20_30680 - 2.7.7.65 ko:K07216,ko:K13590 ko04112,map04112 - - - ko00000,ko00001,ko01000 - - - GGDEF TGS3_k127_3214536_0 1247963.JPHU01000014_gene1025 1.254e-172 556.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the DEAD box helicase family rhlE - 3.6.4.13 ko:K03732,ko:K11927 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C TGS3_k127_3214536_2 402881.Plav_1090 1.225e-52 193.0 COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2U62V@28211|Alphaproteobacteria,1JP4C@119043|Rhodobiaceae 28211|Alphaproteobacteria J Acetyltransferase (GNAT) domain - - - ko:K22479 - - - - ko00000 - - - Acetyltransf_3 TGS3_k127_3214536_6 1121948.AUAC01000006_gene615 5.46e-08 55.0 28M2S@1|root,2ZAH5@2|Bacteria,1MVH5@1224|Proteobacteria,2V6CQ@28211|Alphaproteobacteria,43WPI@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_3219384_0 935840.JAEQ01000029_gene672 3.672e-101 338.0 COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,2TW52@28211|Alphaproteobacteria,43M0X@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K Cupin - - - - - - - - - - - - Cupin_6,HTH_18 TGS3_k127_3219384_1 450851.PHZ_c1673 5.393e-85 295.0 2CCCK@1|root,2Z7UH@2|Bacteria,1R3SV@1224|Proteobacteria,2UH90@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_3219384_3 761193.Runsl_0210 9.62e-32 140.0 COG1680@1|root,COG3653@1|root,COG1680@2|Bacteria,COG3653@2|Bacteria,4NI1Z@976|Bacteroidetes,47NHH@768503|Cytophagia 976|Bacteroidetes QV Beta-lactamase - - - - - - - - - - - - Amidohydro_3,Beta-lactamase TGS3_k127_3219384_2 1121939.L861_03820 3.929e-36 149.0 COG0639@1|root,COG0639@2|Bacteria,1N106@1224|Proteobacteria,1S9QJ@1236|Gammaproteobacteria,1XKQU@135619|Oceanospirillales 135619|Oceanospirillales T Calcineurin-like phosphoesterase - - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos TGS3_k127_3235018_0 1282876.BAOK01000001_gene2895 4.197e-141 469.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2TRQG@28211|Alphaproteobacteria,4BPS7@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N TGS3_k127_3235018_2 314260.PB2503_02112 1.941e-41 165.0 COG1651@1|root,COG1651@2|Bacteria,1RFF4@1224|Proteobacteria,2U5BN@28211|Alphaproteobacteria 28211|Alphaproteobacteria O COG1651 protein-disulfide isomerase MA20_42440 - - - - - - - - - - - Thioredoxin_4 TGS3_k127_3235018_4 1247963.JPHU01000004_gene492 8.273e-10 71.0 COG5389@1|root,COG5389@2|Bacteria 2|Bacteria S Protein of unknown function (DUF721) MA20_42435 - - - - - - - - - - - DUF721 TGS3_k127_3235018_1 1121271.AUCM01000001_gene3687 2.177e-110 381.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2TQVX@28211|Alphaproteobacteria 28211|Alphaproteobacteria L a g-specific adenine glycosylase mutY GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 TGS3_k127_3235018_3 1122137.AQXF01000006_gene866 2.433e-38 144.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TTB9@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) MA20_27300 - 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans TGS3_k127_3241193_5 1121124.JNIX01000007_gene513 4.041e-24 105.0 COG3544@1|root,COG3544@2|Bacteria,1NTI3@1224|Proteobacteria,2UMCM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF305) - - - - - - - - - - - - DUF305 TGS3_k127_3241193_4 1247963.JPHU01000013_gene695 2.365e-51 194.0 COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,2TUFD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - ko:K09798 - - - - ko00000 - - - Polysacc_deac_2 TGS3_k127_3241193_3 1247963.JPHU01000013_gene694 1.339e-67 239.0 COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2TU3N@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH Anthranilate synthase trpG - 2.6.1.85,4.1.3.27 ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase TGS3_k127_3241193_0 1207063.P24_10445 1.409e-107 359.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2TR8S@28211|Alphaproteobacteria,2JQYM@204441|Rhodospirillales 204441|Rhodospirillales E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD - 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase,Glycos_trans_3N,Glycos_transf_3 TGS3_k127_3241193_1 1082933.MEA186_27180 4.806e-92 311.0 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2TSZE@28211|Alphaproteobacteria,43HRV@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - - IGPS TGS3_k127_3241193_2 450851.PHZ_c1762 4.271e-87 294.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2TT7W@28211|Alphaproteobacteria,2KF4D@204458|Caulobacterales 204458|Caulobacterales K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0033554,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 TGS3_k127_3256122_0 631454.N177_1272 1.23e-141 463.0 COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2TR6W@28211|Alphaproteobacteria,1JN3V@119043|Rhodobiaceae 28211|Alphaproteobacteria E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase TGS3_k127_3256122_1 1247963.JPHU01000014_gene990 2.706e-26 117.0 COG4530@1|root,COG4530@2|Bacteria 2|Bacteria P PFAM conserved MA20_24185 - - - - - - - - - - - FYDLN_acid TGS3_k127_3256122_2 1247024.JRLH01000002_gene196 2.72e-05 47.0 2DT3B@1|root,33IHT@2|Bacteria,1NK4F@1224|Proteobacteria,1SHSY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_3256122_3 1502851.FG93_06000 0.0002177 44.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2TSP6@28211|Alphaproteobacteria,3JU6G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind TGS3_k127_328592_1 1121033.AUCF01000003_gene3458 7.43e-81 279.0 COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,2JPEG@204441|Rhodospirillales 204441|Rhodospirillales FL 6-O-methylguanine DNA methyltransferase, DNA binding domain ada - 2.1.1.63 ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N TGS3_k127_328592_2 648885.KB316282_gene1833 9.183e-62 223.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2TTY7@28211|Alphaproteobacteria,1JTF3@119045|Methylobacteriaceae 28211|Alphaproteobacteria E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC GO:0003674,GO:0003824,GO:0004735,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer TGS3_k127_328592_3 1123320.KB889730_gene5871 2.081e-09 59.0 COG1215@1|root,COG1215@2|Bacteria,2GJZI@201174|Actinobacteria 201174|Actinobacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 TGS3_k127_328592_0 1150469.RSPPHO_00434 1.757e-81 281.0 COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2TT8U@28211|Alphaproteobacteria,2JRV8@204441|Rhodospirillales 204441|Rhodospirillales I Squalene/phytoene synthase - - 2.5.1.103,4.2.3.156 ko:K21678,ko:K21679 - - - - ko00000,ko01000 - - - SQS_PSY TGS3_k127_328592_4 1088869.GMO_10570 9.45e-09 62.0 COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2TTI0@28211|Alphaproteobacteria,2JRHF@204441|Rhodospirillales 204441|Rhodospirillales I Phytoene synthase - - 2.5.1.103 ko:K21678 - - - - ko00000,ko01000 - - - SQS_PSY TGS3_k127_328632_6 1247963.JPHU01000009_gene2343 3.891e-42 156.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,2TSZI@28211|Alphaproteobacteria 28211|Alphaproteobacteria H GTP cyclohydrolase folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI TGS3_k127_328632_4 1174684.EBMC1_13793 5.315e-70 250.0 COG3917@1|root,COG3917@2|Bacteria,1RA6I@1224|Proteobacteria,2U5JB@28211|Alphaproteobacteria,2K4JJ@204457|Sphingomonadales 204457|Sphingomonadales Q 2-hydroxychromene-2-carboxylate isomerase - - - - - - - - - - - - DSBA TGS3_k127_328632_3 1280953.HOC_07108 1.87e-107 353.0 COG1028@1|root,COG1028@2|Bacteria,1MWJQ@1224|Proteobacteria,2TVRP@28211|Alphaproteobacteria,43WKB@69657|Hyphomonadaceae 28211|Alphaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) MA20_07325 - - - - - - - - - - - adh_short TGS3_k127_328632_2 1247963.JPHU01000003_gene1487 9.045e-122 402.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2TRF8@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh TGS3_k127_328632_7 1150864.MILUP08_42206 1.98e-22 100.0 COG3502@1|root,COG3502@2|Bacteria,2GV87@201174|Actinobacteria,4DG1H@85008|Micromonosporales 201174|Actinobacteria S Protein of unknown function (DUF952) - - - - - - - - - - - - DUF952 TGS3_k127_328632_9 394221.Mmar10_0515 2.736e-15 85.0 COG0457@1|root,COG0457@2|Bacteria,1R3PT@1224|Proteobacteria,2TXA0@28211|Alphaproteobacteria,440T7@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - TGS3_k127_328632_1 1453501.JELR01000002_gene51 1.412e-163 526.0 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RPU5@1236|Gammaproteobacteria,46411@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters sdcS - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp TGS3_k127_328632_8 1122970.AUHC01000002_gene1246 2.519e-16 92.0 2ETWY@1|root,32VZU@2|Bacteria,1R3ET@1224|Proteobacteria,2U01S@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_328632_5 1247963.JPHU01000003_gene1490 2.418e-48 177.0 COG4103@1|root,COG4103@2|Bacteria,1QYQI@1224|Proteobacteria,2TXVZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tellurite resistance protein TerB - - - - - - - - - - - - TerB TGS3_k127_328632_0 314260.PB2503_07232 8.381e-206 650.0 COG1384@1|root,COG1384@2|Bacteria,1MV32@1224|Proteobacteria,2TQYH@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04566 ko00970,map00970 M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1f TGS3_k127_3288383_0 1247963.JPHU01000003_gene1335 1.134e-194 634.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2TRX2@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 TGS3_k127_3288383_1 1247963.JPHU01000003_gene1336 1.028e-130 428.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2TTV2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Peptidase M48 MA20_29180 - - - - - - - - - - - Peptidase_M48,TPR_16,TPR_19 TGS3_k127_3296328_4 1218076.BAYB01000009_gene1861 9.008e-07 53.0 COG1028@1|root,COG1028@2|Bacteria,1MU73@1224|Proteobacteria,2VQTS@28216|Betaproteobacteria,1K21T@119060|Burkholderiaceae 28216|Betaproteobacteria IQ Short-chain dehydrogenase reductase sdr - - - - - - - - - - - - adh_short_C2 TGS3_k127_3296328_2 450851.PHZ_c3068 1.046e-99 334.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2TRSK@28211|Alphaproteobacteria,2KFPC@204458|Caulobacterales 204458|Caulobacterales K Transcriptional regulatory protein - - - - - - - - - - - - Transcrip_reg TGS3_k127_3296328_1 551789.ATVJ01000001_gene2392 4.254e-172 565.0 COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,2V4NX@28211|Alphaproteobacteria,43YZT@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Carbohydrate family 9 binding domain-like - - - - - - - - - - - - CBM9_1 TGS3_k127_3296328_0 1247963.JPHU01000008_gene2816 8.866e-177 558.0 COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2TS1Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria S cobaltochelatase, CobS subunit cobS - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5,CbbQ_C,CobS_N TGS3_k127_3296328_3 314260.PB2503_00882 2.693e-22 97.0 COG2214@1|root,COG2214@2|Bacteria,1MXTG@1224|Proteobacteria,2TRZH@28211|Alphaproteobacteria 28211|Alphaproteobacteria O molecular chaperone - - - - - - - - - - - - DnaJ TGS3_k127_3302565_1 1247963.JPHU01000001_gene1768 9.474e-106 355.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2TREW@28211|Alphaproteobacteria 28211|Alphaproteobacteria L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N TGS3_k127_3302565_2 1247963.JPHU01000010_gene2251 1.574e-94 321.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2TRZ5@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamD - - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO TGS3_k127_3302565_3 1525715.IX54_07285 1.966e-65 238.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2TUHH@28211|Alphaproteobacteria,2PV6J@265|Paracoccus 28211|Alphaproteobacteria M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC TGS3_k127_3302565_0 314260.PB2503_08519 2.801e-163 529.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2TS1Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin TGS3_k127_3304985_3 1219035.NT2_02_01370 9.311e-10 59.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2TRV3@28211|Alphaproteobacteria,2K21F@204457|Sphingomonadales 204457|Sphingomonadales T Phosphate starvation-inducible protein PhoH - - - ko:K06217 - - - - ko00000 - - - PhoH TGS3_k127_3304985_2 1161401.ASJA01000003_gene2764 4.614e-40 154.0 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2UBXV@28211|Alphaproteobacteria,43YAG@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 TGS3_k127_3304985_0 1247963.JPHU01000002_gene2683 1.135e-87 299.0 COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TVFA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG1253 Hemolysins and related proteins containing CBS domains tlyC - - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC TGS3_k127_3304985_1 314260.PB2503_04262 1.586e-61 224.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2TQRC@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase TGS3_k127_3310253_2 1429916.X566_14235 2.817e-19 92.0 COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,2UCHH@28211|Alphaproteobacteria,3JRET@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Required for flagellar hook formation. May act as a scaffolding protein flgD - - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FLgD_tudor,FlgD,FlgD_ig TGS3_k127_3310253_3 402881.Plav_2187 9.712e-08 63.0 COG3144@1|root,COG3144@2|Bacteria,1N7X4@1224|Proteobacteria,2UF9W@28211|Alphaproteobacteria,1JQDR@119043|Rhodobiaceae 28211|Alphaproteobacteria N Flagellar hook-length control protein FliK - - - ko:K10565 - - - - ko00000,ko02035 - - - Flg_hook TGS3_k127_3310253_0 1121878.AUGL01000008_gene1474 1.483e-26 126.0 COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria 1236|Gammaproteobacteria N flagellar hook-associated protein flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C TGS3_k127_3310253_1 1449049.JONW01000008_gene569 3.415e-26 120.0 COG1344@1|root,COG1344@2|Bacteria,1NSHZ@1224|Proteobacteria,2TRS6@28211|Alphaproteobacteria,2KGEY@204458|Caulobacterales 204458|Caulobacterales N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella - - - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N TGS3_k127_3322451_11 394221.Mmar10_0710 1.17e-28 119.0 COG0824@1|root,COG0824@2|Bacteria,1N06V@1224|Proteobacteria,2UCAQ@28211|Alphaproteobacteria,43ZWX@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Acyl-ACP thioesterase - - - ko:K07107 - - - - ko00000,ko01000 - - - Acyl-ACP_TE TGS3_k127_3322451_0 991905.SL003B_3005 4.879e-184 593.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,2TUH6@28211|Alphaproteobacteria,4BPPB@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P Sulfate permease family sulP - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp TGS3_k127_3322451_10 648885.KB316282_gene1805 1.433e-29 121.0 COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2U7H7@28211|Alphaproteobacteria,1JVBA@119045|Methylobacteriaceae 28211|Alphaproteobacteria K transcriptional regulator, ArsR family - - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_20 TGS3_k127_3322451_8 420662.Mpe_A2346 6.641e-39 149.0 COG0346@1|root,COG0346@2|Bacteria,1RHIV@1224|Proteobacteria,2VQPS@28216|Betaproteobacteria,1KKRE@119065|unclassified Burkholderiales 28216|Betaproteobacteria E PFAM Glyoxalase bleomycin resistance protein dioxygenase cadI - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase TGS3_k127_3322451_7 243233.MCA1387 8.496e-45 170.0 COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,1S2YD@1236|Gammaproteobacteria,1XF40@135618|Methylococcales 135618|Methylococcales T PFAM Protein-tyrosine phosphatase, low molecular weight - - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc TGS3_k127_3322451_4 1248760.ANFZ01000014_gene2115 1.139e-67 237.0 COG0580@1|root,COG0580@2|Bacteria,1PPTN@1224|Proteobacteria,2TW8M@28211|Alphaproteobacteria,2K1WK@204457|Sphingomonadales 204457|Sphingomonadales G Belongs to the MIP aquaporin (TC 1.A.8) family - - - - - - - - - - - - MIP TGS3_k127_3322451_1 394221.Mmar10_2833 1.675e-122 406.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2TRG1@28211|Alphaproteobacteria,43WCS@69657|Hyphomonadaceae 28211|Alphaproteobacteria S AFG1 family ATPase zapE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase TGS3_k127_3322451_3 1122613.ATUP01000001_gene784 2.31e-83 293.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRJ1@28211|Alphaproteobacteria,43X4R@69657|Hyphomonadaceae 28211|Alphaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily MA20_32310 - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 TGS3_k127_3322451_9 1122218.KB893663_gene1697 6.175e-34 139.0 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2U9UT@28211|Alphaproteobacteria,1JQZT@119045|Methylobacteriaceae 28211|Alphaproteobacteria J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM TGS3_k127_3322451_12 1033736.CAHK01000013_gene967 8.737e-06 59.0 COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4F9E7@85019|Brevibacteriaceae 201174|Actinobacteria O PDZ domain (Also known as DHR or GLGF) degP - - ko:K08372 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Trypsin_2 TGS3_k127_3322451_2 1479238.JQMZ01000001_gene670 6.707e-92 308.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2TSIZ@28211|Alphaproteobacteria,43WA0@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT TGS3_k127_3322451_5 419610.Mext_4734 2.629e-55 195.0 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2U9DF@28211|Alphaproteobacteria,1JUYZ@119045|Methylobacteriaceae 28211|Alphaproteobacteria J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 TGS3_k127_3322451_6 329726.AM1_0056 4.192e-52 190.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - GNAT_acetyltran,Polyketide_cyc2 TGS3_k127_3324889_2 1192868.CAIU01000013_gene1524 4.908e-86 290.0 COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,2TQQD@28211|Alphaproteobacteria,43JES@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA TGS3_k127_3324889_4 1411123.JQNH01000001_gene730 1.117e-67 237.0 COG0457@1|root,COG0457@2|Bacteria,1QZ3D@1224|Proteobacteria,2TY43@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative 2OG-Fe(II) oxygenase - - - - - - - - - - - - 2OG-FeII_Oxy_5 TGS3_k127_3324889_6 631362.Thi970DRAFT_02176 1.257e-28 127.0 COG2242@1|root,COG2242@2|Bacteria,1NDIK@1224|Proteobacteria 1224|Proteobacteria H Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 TGS3_k127_3324889_0 685035.ADAE01000003_gene2834 2.131e-139 452.0 COG0604@1|root,COG0604@2|Bacteria,1QUNT@1224|Proteobacteria,2TW28@28211|Alphaproteobacteria,2K36M@204457|Sphingomonadales 204457|Sphingomonadales C Protein of unknown function (DUF2855) - - - - - - - - - - - - DUF2855 TGS3_k127_3324889_1 414684.RC1_1580 2.916e-101 335.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,2JQ66@204441|Rhodospirillales 204441|Rhodospirillales Q COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component mkl - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran TGS3_k127_3324889_3 366602.Caul_1577 4.974e-86 292.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,2KG0B@204458|Caulobacterales 204458|Caulobacterales Q Permease MlaE - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE TGS3_k127_3324889_5 1121949.AQXT01000002_gene475 3.163e-49 183.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2TQKD@28211|Alphaproteobacteria,43W8B@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N TGS3_k127_3334895_4 194867.ALBQ01000011_gene384 7.15e-08 55.0 COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria,2TW4W@28211|Alphaproteobacteria,2JZYG@204457|Sphingomonadales 204457|Sphingomonadales H receptor - - - - - - - - - - - - Plug TGS3_k127_3334895_1 1121033.AUCF01000004_gene5058 1.491e-73 257.0 COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,2TU5K@28211|Alphaproteobacteria,2JQRQ@204441|Rhodospirillales 204441|Rhodospirillales J Specifically methylates the adenine in position 2030 of 23S rRNA rlmJ - 2.1.1.266 ko:K07115 - - - - ko00000,ko01000,ko03009 - - - RsmJ TGS3_k127_3334895_2 935840.JAEQ01000023_gene4360 2.114e-43 163.0 COG0261@1|root,COG3743@1|root,COG0261@2|Bacteria,COG3743@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,43H1I@69277|Phyllobacteriaceae 28211|Alphaproteobacteria J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - HHH_5,Ribosomal_L21p TGS3_k127_3334895_3 1408427.JADB01000002_gene1174 9.951e-36 137.0 COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2UBUX@28211|Alphaproteobacteria,48U7Q@772|Bartonellaceae 28211|Alphaproteobacteria J structural constituent of ribosome rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 TGS3_k127_3334895_0 1449049.JONW01000005_gene1304 9.209e-99 328.0 COG2234@1|root,COG2234@2|Bacteria,1MUZ7@1224|Proteobacteria,2TRSJ@28211|Alphaproteobacteria,2KG5D@204458|Caulobacterales 204458|Caulobacterales S PA domain - - - - - - - - - - - - PA,Peptidase_M28 TGS3_k127_3339901_8 1247963.JPHU01000003_gene1516 4.425e-11 67.0 COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2TRJ6@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q dithiol-disulfide isomerase involved in polyketide biosynthesis dsb - - - - - - - - - - - DSBA TGS3_k127_3339901_5 1238182.C882_1586 7.119e-29 129.0 COG3420@1|root,COG3420@2|Bacteria,1R5QH@1224|Proteobacteria,2U3Y9@28211|Alphaproteobacteria,2JSRP@204441|Rhodospirillales 204441|Rhodospirillales P Parallel beta-helix repeats - - - - - - - - - - - - Beta_helix TGS3_k127_3339901_7 391600.ABRU01000056_gene576 3.479e-26 109.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,2KJ93@204458|Caulobacterales 204458|Caulobacterales K Cold-shock protein - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD TGS3_k127_3339901_0 1122137.AQXF01000002_gene462 1.737e-221 707.0 COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,2TUNP@28211|Alphaproteobacteria 28211|Alphaproteobacteria H receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec TGS3_k127_3339901_2 935848.JAEN01000001_gene3532 3.857e-111 375.0 COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TSGF@28211|Alphaproteobacteria,2PWNB@265|Paracoccus 28211|Alphaproteobacteria I 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N TGS3_k127_3339901_3 991905.SL003B_2150 5.129e-93 311.0 COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,2TUTT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S phenylacetic acid - - - - - - - - - - - - PaaA_PaaC TGS3_k127_3339901_1 935557.ATYB01000008_gene5703 4.214e-154 493.0 COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,2U0WY@28211|Alphaproteobacteria,4B73A@82115|Rhizobiaceae 28211|Alphaproteobacteria C Oxidoreductase NAD-binding domain paaK - - ko:K02613 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FAD_binding_6,Fer2,NAD_binding_1 TGS3_k127_3339901_9 1415779.JOMH01000001_gene2117 0.0005679 45.0 COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,1RPZN@1236|Gammaproteobacteria,1X463@135614|Xanthomonadales 135614|Xanthomonadales S Nitronate monooxygenase - - - - - - - - - - - - NMO TGS3_k127_3339901_4 412597.AEPN01000006_gene1619 2.073e-59 212.0 COG2151@1|root,COG2151@2|Bacteria,1RF3S@1224|Proteobacteria,2TRQW@28211|Alphaproteobacteria,2PWIP@265|Paracoccus 28211|Alphaproteobacteria S Pfam:DUF59 paaD - - ko:K02612 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FeS_assembly_P TGS3_k127_3339901_6 1185766.DL1_21045 2.716e-27 113.0 COG3396@1|root,COG3396@2|Bacteria,1MVYQ@1224|Proteobacteria,2TRYF@28211|Alphaproteobacteria 28211|Alphaproteobacteria S phenylacetic acid degradation protein paaI - 1.14.13.149 ko:K02611 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC TGS3_k127_3349538_5 426355.Mrad2831_5251 7.932e-06 53.0 COG2353@1|root,COG2353@2|Bacteria,1RJFZ@1224|Proteobacteria,2UBXA@28211|Alphaproteobacteria,1JX5Z@119045|Methylobacteriaceae 28211|Alphaproteobacteria S YceI-like domain - - - - - - - - - - - - YceI TGS3_k127_3349538_2 316056.RPC_2322 1.955e-46 174.0 COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,2UBYU@28211|Alphaproteobacteria,3JVNU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Prokaryotic cytochrome b561 yceJ - - ko:K12262 - - - - ko00000 - - - Ni_hydr_CYTB TGS3_k127_3349538_3 1121948.AUAC01000002_gene1717 2.875e-45 173.0 COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2TVD3@28211|Alphaproteobacteria,43XT2@69657|Hyphomonadaceae 28211|Alphaproteobacteria S YceI-like domain - - - - - - - - - - - - YceI TGS3_k127_3349538_1 1247963.JPHU01000003_gene1346 9.856e-61 215.0 COG0778@1|root,COG0778@2|Bacteria,1PKUV@1224|Proteobacteria,2U5MZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Nitroreductase - - - - - - - - - - - - Nitroreductase TGS3_k127_3349538_0 402881.Plav_1883 2.632e-185 600.0 COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria 1224|Proteobacteria P Receptor - - - - - - - - - - - - Plug,TonB_dep_Rec TGS3_k127_3349538_4 1449076.JOOE01000002_gene1440 3.412e-35 139.0 COG0346@1|root,COG0346@2|Bacteria,1N6KJ@1224|Proteobacteria,2UCJG@28211|Alphaproteobacteria 28211|Alphaproteobacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase TGS3_k127_337558_0 69395.JQLZ01000002_gene1178 3.076e-125 406.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2KG3B@204458|Caulobacterales 204458|Caulobacterales I Belongs to the thiolase family - - 2.3.1.174,2.3.1.9 ko:K00626,ko:K07823 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R00829,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N TGS3_k127_337558_2 1331060.RLDS_04055 6.451e-37 144.0 COG2050@1|root,COG2050@2|Bacteria,1RH35@1224|Proteobacteria,2U5QW@28211|Alphaproteobacteria,2K6MG@204457|Sphingomonadales 204457|Sphingomonadales Q Thioesterase superfamily - - - ko:K02614 ko00360,map00360 - R09840 RC00004,RC00014 ko00000,ko00001,ko01000 - - - 4HBT TGS3_k127_337558_1 392499.Swit_0749 8.116e-112 367.0 COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2TUXD@28211|Alphaproteobacteria,2K0UE@204457|Sphingomonadales 204457|Sphingomonadales I enoyl-CoA hydratase - - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 TGS3_k127_3389631_1 536019.Mesop_6169 3.19e-44 162.0 COG1813@1|root,COG1813@2|Bacteria,1QVBI@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_31 TGS3_k127_3389631_4 9483.ENSCJAP00000020379 0.0007647 44.0 KOG3519@1|root,KOG3519@2759|Eukaryota,38H4U@33154|Opisthokonta,3BAWQ@33208|Metazoa,3CTCW@33213|Bilateria,48194@7711|Chordata,48YFM@7742|Vertebrata,3J27A@40674|Mammalia,359S8@314146|Euarchontoglires,4MKPK@9443|Primates 33208|Metazoa T Rac guanyl-nucleotide exchange factor activity ARHGEF4 GO:0003674,GO:0005085,GO:0005088,GO:0005089,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0007154,GO:0007165,GO:0007186,GO:0008150,GO:0009966,GO:0009987,GO:0010646,GO:0010941,GO:0010942,GO:0016043,GO:0017016,GO:0017048,GO:0019899,GO:0019904,GO:0022607,GO:0023051,GO:0023052,GO:0030030,GO:0030031,GO:0030032,GO:0030676,GO:0031267,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046847,GO:0048365,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051056,GO:0051716,GO:0065007,GO:0065009,GO:0071840,GO:0097581,GO:0098772,GO:0120031,GO:0120036,GO:1902531 - ko:K05769 ko04810,map04810 - - - ko00000,ko00001,ko04131 - - - PH,RhoGEF,SH3_1,SH3_2 TGS3_k127_3389631_3 1380350.JIAP01000002_gene4215 4.956e-05 48.0 COG4715@1|root,COG4715@2|Bacteria,1R60K@1224|Proteobacteria,2U4S9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Zinc finger, swim domain protein - - - - - - - - - - - - SWIM TGS3_k127_3389631_2 1134912.AJTV01000021_gene3059 2.159e-22 101.0 COG4715@1|root,COG4715@2|Bacteria,1R60K@1224|Proteobacteria,2U4S9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Zinc finger, swim domain protein - - - - - - - - - - - - SWIM TGS3_k127_3389631_0 314260.PB2503_02617 8.65e-184 581.0 COG1257@1|root,COG1257@2|Bacteria,1Q6M1@1224|Proteobacteria,2U1F3@28211|Alphaproteobacteria 28211|Alphaproteobacteria I COG1257 Hydroxymethylglutaryl-CoA reductase - - 1.1.1.34 ko:K00021 ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976 M00095 R02082 RC00004,RC00644 ko00000,ko00001,ko00002,ko01000 - - - HMG-CoA_red TGS3_k127_3393638_0 1280954.HPO_15568 7.399e-183 586.0 COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,2TSZJ@28211|Alphaproteobacteria,4414B@69657|Hyphomonadaceae 28211|Alphaproteobacteria P Sodium/hydrogen exchanger family cvrA - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - CorC_HlyC,Na_H_Exchanger TGS3_k127_3393638_3 1280947.HY30_07975 1.777e-39 158.0 COG5031@1|root,COG5031@2|Bacteria,1RGXT@1224|Proteobacteria,2U8F1@28211|Alphaproteobacteria,440X5@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Coenzyme Q (ubiquinone) biosynthesis protein Coq4 - - - ko:K18586 - - - - ko00000 - - - Coq4 TGS3_k127_3393638_1 1041147.AUFB01000002_gene3132 1.905e-102 340.0 COG0500@1|root,COG2226@2|Bacteria,1R439@1224|Proteobacteria,2U0N2@28211|Alphaproteobacteria,4BA6K@82115|Rhizobiaceae 28211|Alphaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 TGS3_k127_3393638_2 269796.Rru_A1080 4.506e-68 237.0 COG0352@1|root,COG0352@2|Bacteria,1MV42@1224|Proteobacteria,2TSSA@28211|Alphaproteobacteria,2JQJQ@204441|Rhodospirillales 204441|Rhodospirillales H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI TGS3_k127_3393638_4 244582.JQAK01000004_gene201 2.9e-25 117.0 COG0790@1|root,COG3591@1|root,COG0790@2|Bacteria,COG3591@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Sel1 domain protein repeat-containing protein - - - ko:K07126 - - - - ko00000 - - - Sel1 TGS3_k127_3407776_0 698440.XP_007294669.1 0.0004242 51.0 2DQSB@1|root,2S6CI@2759|Eukaryota,3A5I3@33154|Opisthokonta,3P43Y@4751|Fungi,3QX5Z@4890|Ascomycota 4751|Fungi - - - - - - - - - - - - - - LysM,SLT TGS3_k127_3413625_11 314260.PB2503_09639 2.455e-30 128.0 COG0483@1|root,COG0483@2|Bacteria,1NFR1@1224|Proteobacteria,2U1X2@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Inositol monophosphatase - - - - - - - - - - - - Inositol_P TGS3_k127_3413625_4 314260.PB2503_11929 1.511e-156 506.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2TUXJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 TGS3_k127_3413625_10 1294273.roselon_02897 1.034e-38 145.0 COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2UBTW@28211|Alphaproteobacteria 28211|Alphaproteobacteria J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs hfq GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0009399,GO:0071941,GO:0097159,GO:1901363 - ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 - - - ko00000,ko00001,ko03019,ko03036 - - - Hfq TGS3_k127_3413625_2 627192.SLG_11500 7.452e-191 607.0 COG1409@1|root,COG1409@2|Bacteria,1NS3S@1224|Proteobacteria,2U224@28211|Alphaproteobacteria,2K2QY@204457|Sphingomonadales 204457|Sphingomonadales S Purple acid Phosphatase, N-terminal domain - - - - - - - - - - - - Metallophos,Pur_ac_phosph_N TGS3_k127_3413625_7 1382303.JPOM01000001_gene1299 7.006e-103 344.0 COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2TR7R@28211|Alphaproteobacteria,2KF88@204458|Caulobacterales 204458|Caulobacterales EH Catalyzes the transamination of D-amino acids and their alpha-keto acids - - 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 TGS3_k127_3413625_1 314260.PB2503_11944 4.284e-191 606.0 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,2TRP9@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0569 K transport systems, NAD-binding component trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N TGS3_k127_3413625_0 1247963.JPHU01000009_gene2315 9.92e-198 625.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains ntrX - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat TGS3_k127_3413625_3 1247963.JPHU01000009_gene2316 1.142e-162 540.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2TQTB@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation ntrY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K13598 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 TGS3_k127_3413625_6 1247963.JPHU01000009_gene2317 1.349e-112 373.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2TRC8@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus TGS3_k127_3413625_13 390989.JOEG01000003_gene4404 4.491e-12 70.0 COG2161@1|root,COG2161@2|Bacteria,2GZJV@201174|Actinobacteria 201174|Actinobacteria D Antitoxin component of a toxin-antitoxin (TA) module - - - - - - - - - - - - PhdYeFM_antitox TGS3_k127_3413625_8 83406.HDN1F_29850 4.939e-46 170.0 COG1487@1|root,COG1487@2|Bacteria,1RIB5@1224|Proteobacteria,1S7MG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PIN domain - - - ko:K07062 - - - - ko00000,ko01000,ko02048 - - - PIN TGS3_k127_3413625_5 1122962.AULH01000008_gene2260 1.153e-135 444.0 COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,2TRQC@28211|Alphaproteobacteria,36XGA@31993|Methylocystaceae 28211|Alphaproteobacteria I YgbB family ispDF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD,YgbB TGS3_k127_3413625_12 1500306.JQLA01000020_gene6447 1.49e-21 100.0 2E3KZ@1|root,32YJ8@2|Bacteria,1N7A7@1224|Proteobacteria,2UFMR@28211|Alphaproteobacteria,4BG6V@82115|Rhizobiaceae 28211|Alphaproteobacteria S Putative prokaryotic signal transducing protein MA20_42240 - - - - - - - - - - - DUF2007 TGS3_k127_3413625_9 414684.RC1_0125 4.534e-45 173.0 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2U94H@28211|Alphaproteobacteria,2JSR4@204441|Rhodospirillales 204441|Rhodospirillales S Belongs to the CinA family - - 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA TGS3_k127_3418116_3 394221.Mmar10_2124 7.626e-06 57.0 2ENS1@1|root,33GD6@2|Bacteria,1NM98@1224|Proteobacteria,2UJZE@28211|Alphaproteobacteria,43ZXJ@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_3418116_2 190650.CC_2297 3.706e-52 197.0 COG0739@1|root,COG0739@2|Bacteria,1QGHU@1224|Proteobacteria,2TUF9@28211|Alphaproteobacteria,2KGPY@204458|Caulobacterales 204458|Caulobacterales M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - Peptidase_M23 TGS3_k127_3418116_1 1122214.AQWH01000023_gene391 6.967e-54 193.0 COG3791@1|root,COG3791@2|Bacteria,1PSIB@1224|Proteobacteria,2VANR@28211|Alphaproteobacteria,2PM6Y@255475|Aurantimonadaceae 28211|Alphaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA TGS3_k127_3418116_0 1121123.AUAO01000003_gene2295 6.091e-150 484.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2TRQ5@28211|Alphaproteobacteria,2KFSJ@204458|Caulobacterales 204458|Caulobacterales E Belongs to the peptidase M24B family - - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 TGS3_k127_343851_0 1247963.JPHU01000003_gene1440 5.676e-91 312.0 COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - 2.7.13.3 ko:K20974 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,Response_reg,SBP_bac_3,dCache_1 TGS3_k127_343851_1 663610.JQKO01000001_gene1028 4.898e-79 278.0 COG0577@1|root,COG0577@2|Bacteria,1P0WE@1224|Proteobacteria,2VG3S@28211|Alphaproteobacteria,3NBZM@45404|Beijerinckiaceae 28211|Alphaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD TGS3_k127_343851_2 1121124.JNIX01000008_gene2433 5.272e-73 253.0 COG1136@1|root,COG1136@2|Bacteria,1QT8W@1224|Proteobacteria,2U3UE@28211|Alphaproteobacteria,2KIRV@204458|Caulobacterales 204458|Caulobacterales V ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran TGS3_k127_343851_3 335283.Neut_0975 1.975e-05 55.0 COG0845@1|root,COG0845@2|Bacteria,1NBFC@1224|Proteobacteria,2VN3T@28216|Betaproteobacteria,373M5@32003|Nitrosomonadales 28216|Betaproteobacteria M Biotin-lipoyl like - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2 TGS3_k127_3470190_0 1282362.AEAC466_15505 0.0 1099.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2TSCN@28211|Alphaproteobacteria,2KFFJ@204458|Caulobacterales 204458|Caulobacterales L DNA polymerase - GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon TGS3_k127_3470190_1 314260.PB2503_02502 5.137e-122 395.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2TRXE@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 TGS3_k127_3470190_2 1247963.JPHU01000007_gene1610 1.841e-110 365.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2TQM0@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS TGS3_k127_3470190_3 1247963.JPHU01000007_gene1612 3.905e-109 357.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2TQYN@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase TGS3_k127_3470190_5 314260.PB2503_02482 1.721e-68 238.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2U5B2@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF TGS3_k127_3470190_4 1247963.JPHU01000007_gene1614 2.183e-87 296.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TTVJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf TGS3_k127_3470190_6 314260.PB2503_02462 1.898e-14 78.0 COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,2TZY0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 TGS3_k127_3473944_1 1121948.AUAC01000002_gene1949 5.107e-93 314.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2TSDU@28211|Alphaproteobacteria,43XRG@69657|Hyphomonadaceae 28211|Alphaproteobacteria V MatE norM - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE TGS3_k127_3473944_0 1123269.NX02_13500 0.0 1421.0 COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,2TUU6@28211|Alphaproteobacteria,2K0I3@204457|Sphingomonadales 204457|Sphingomonadales QU Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - Amidohydro_1,PD40 TGS3_k127_347433_12 314260.PB2503_07202 3.662e-29 125.0 2CIPC@1|root,2Z9HB@2|Bacteria,1R3W8@1224|Proteobacteria,2TST7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Glycosyltransferase family 87 - - - - - - - - - - - - GT87 TGS3_k127_347433_2 1500894.JQNN01000001_gene3498 1.858e-114 380.0 COG1215@1|root,COG1215@2|Bacteria,1QTWU@1224|Proteobacteria,2WGWG@28216|Betaproteobacteria,4792Y@75682|Oxalobacteraceae 28216|Betaproteobacteria M Glycosyltransferase like family 2 - - - ko:K20534 - - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 TGS3_k127_347433_11 1110502.TMO_2697 1.047e-44 183.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2TTX6@28211|Alphaproteobacteria,2JPI9@204441|Rhodospirillales 204441|Rhodospirillales S RmuC family rmuC - - ko:K09760 - - - - ko00000 - - - RmuC TGS3_k127_347433_6 314260.PB2503_05022 3.087e-74 252.0 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2U797@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 - R00653 RC00165,RC00323 ko00000,ko00001,ko01000 - - - Pep_deformylase TGS3_k127_347433_3 190650.CC_0279 3.823e-111 367.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2TSWX@28211|Alphaproteobacteria,2KFHF@204458|Caulobacterales 204458|Caulobacterales J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N TGS3_k127_347433_4 1101190.ARWB01000001_gene3281 2.414e-93 312.0 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2TR57@28211|Alphaproteobacteria,36XBX@31993|Methylocystaceae 28211|Alphaproteobacteria J tRNA pseudouridine synthase truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 TGS3_k127_347433_1 1207063.P24_09756 6.441e-137 445.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2TT0J@28211|Alphaproteobacteria,2JQ29@204441|Rhodospirillales 204441|Rhodospirillales E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 TGS3_k127_347433_10 1532558.JL39_27035 7.861e-48 177.0 COG3837@1|root,COG3837@2|Bacteria,1R9WZ@1224|Proteobacteria,2U6K6@28211|Alphaproteobacteria,4BEBY@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF861) - - - - - - - - - - - - Cupin_2 TGS3_k127_347433_7 1122218.KB893654_gene2222 8.809e-67 245.0 COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,2TS9S@28211|Alphaproteobacteria,1JS4Z@119045|Methylobacteriaceae 28211|Alphaproteobacteria I PFAM membrane protein involved in aromatic hydrocarbon degradation - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X TGS3_k127_347433_14 1089552.KI911559_gene2933 1.542e-08 67.0 COG0642@1|root,COG2205@2|Bacteria,1MXY0@1224|Proteobacteria,2U4WV@28211|Alphaproteobacteria 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA TGS3_k127_347433_9 1353529.M899_1785 1.068e-51 192.0 COG0819@1|root,COG0819@2|Bacteria,1QWWX@1224|Proteobacteria 1224|Proteobacteria K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway - - - - - - - - - - - - - TGS3_k127_347433_13 237368.SCABRO_01065 9.273e-12 75.0 COG3176@1|root,COG3176@2|Bacteria 2|Bacteria S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_5,Aminotran_5,cNMP_binding TGS3_k127_347433_8 1247963.JPHU01000003_gene1303 5.207e-60 211.0 COG0745@1|root,COG0745@2|Bacteria,1QUSA@1224|Proteobacteria,2TW5G@28211|Alphaproteobacteria 28211|Alphaproteobacteria T response regulator QU41_05915 - - ko:K13589 ko02020,ko04112,map02020,map04112 M00512 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg TGS3_k127_347433_5 1380391.JIAS01000020_gene1477 6.878e-87 296.0 COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2TUPZ@28211|Alphaproteobacteria,2JQS5@204441|Rhodospirillales 204441|Rhodospirillales E N-formylglutamate amidohydrolase - - 3.5.1.68 ko:K01458 ko00340,ko00630,map00340,map00630 - R00525 RC00165,RC00323 ko00000,ko00001,ko01000 - - - FGase TGS3_k127_347433_0 314260.PB2503_01312 9.558e-173 550.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2TQQ0@28211|Alphaproteobacteria 28211|Alphaproteobacteria M glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 TGS3_k127_3484303_1 314260.PB2503_09804 9.328e-93 328.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2TQV5@28211|Alphaproteobacteria 28211|Alphaproteobacteria U COG0457 FOG TPR repeat MA20_42300 - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 TGS3_k127_3484303_0 59538.XP_005984962.1 3.139e-257 803.0 COG2440@1|root,KOG2415@2759|Eukaryota,38H8R@33154|Opisthokonta,3BH2N@33208|Metazoa,3CWV6@33213|Bilateria,484PU@7711|Chordata,48WYX@7742|Vertebrata,3J1P9@40674|Mammalia,4IYEG@91561|Cetartiodactyla 33208|Metazoa C Electron transfer flavoprotein-ubiquinone oxidoreductase - - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO,NAD_binding_8 TGS3_k127_3484303_2 1385517.N800_13810 3.785e-30 128.0 COG3714@1|root,COG3714@2|Bacteria,1QE44@1224|Proteobacteria,1TAFY@1236|Gammaproteobacteria,1X8EB@135614|Xanthomonadales 135614|Xanthomonadales S YhhN family - - - - - - - - - - - - YhhN TGS3_k127_3490004_0 1247963.JPHU01000007_gene1702 6.613e-305 947.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2TS97@28211|Alphaproteobacteria 28211|Alphaproteobacteria C NADH-quinone oxidoreductase nuoG - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3,NADH_dhqG_C TGS3_k127_3490004_1 243231.GSU0213 2.742e-07 54.0 COG1032@1|root,COG1032@2|Bacteria,1PDZR@1224|Proteobacteria,42M73@68525|delta/epsilon subdivisions,2WK6Y@28221|Deltaproteobacteria,43SAZ@69541|Desulfuromonadales 28221|Deltaproteobacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - B12-binding,Radical_SAM TGS3_k127_350070_4 768671.ThimaDRAFT_0164 3.777e-15 75.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1WWHM@135613|Chromatiales 135613|Chromatiales Q TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM TGS3_k127_350070_1 1122613.ATUP01000002_gene2699 8.717e-108 357.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2TS3N@28211|Alphaproteobacteria,43X2J@69657|Hyphomonadaceae 28211|Alphaproteobacteria O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 TGS3_k127_350070_3 1121949.AQXT01000002_gene2567 2.631e-62 221.0 COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,2TRKQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M aspartate racemase - - - - - - - - - - - - Asp_Glu_race TGS3_k127_350070_2 883080.HMPREF9697_01550 1.214e-69 241.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2U6EM@28211|Alphaproteobacteria,3JSVH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S LemA family MA20_42455 - - ko:K03744 - - - - ko00000 - - - LemA TGS3_k127_350070_0 402881.Plav_2454 5.101e-123 402.0 COG3386@1|root,COG3386@2|Bacteria,1MXVD@1224|Proteobacteria,2TVCW@28211|Alphaproteobacteria 28211|Alphaproteobacteria G SMP-30 Gluconolaconase MA20_01275 - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL TGS3_k127_350070_5 477228.YO5_12842 7.183e-10 72.0 28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,1Z09F@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Protein of unknown function (DUF2959) - - - - - - - - - - - - DUF2959 TGS3_k127_3530727_2 685035.ADAE01000018_gene697 1.977e-67 234.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2TT63@28211|Alphaproteobacteria,2K09I@204457|Sphingomonadales 204457|Sphingomonadales H Involved in the biosynthesis of porphyrin-containing compound - - - - - - - - - - - - HemN_C,Radical_SAM TGS3_k127_3530727_4 1121033.AUCF01000003_gene3481 1.254e-36 139.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2TV4B@28211|Alphaproteobacteria,2JRRX@204441|Rhodospirillales 204441|Rhodospirillales F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like TGS3_k127_3530727_3 1537715.JQFJ01000001_gene2639 2.378e-40 156.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2TV4B@28211|Alphaproteobacteria,2K1NS@204457|Sphingomonadales 204457|Sphingomonadales F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like TGS3_k127_3530727_6 1121123.AUAO01000001_gene949 2.179e-13 78.0 2DZQF@1|root,32VG9@2|Bacteria,1MZ9P@1224|Proteobacteria,2UDR3@28211|Alphaproteobacteria,2KGZ4@204458|Caulobacterales 204458|Caulobacterales S Protein of unknown function (DUF2975) - - - - - - - - - - - - DUF2975 TGS3_k127_3530727_5 1280953.HOC_09079 1.202e-28 117.0 COG3655@1|root,COG3655@2|Bacteria,1N6VH@1224|Proteobacteria,2UFAM@28211|Alphaproteobacteria,43Y68@69657|Hyphomonadaceae 28211|Alphaproteobacteria K Transcriptional regulator - - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26 TGS3_k127_3530727_1 551789.ATVJ01000001_gene1246 4.887e-76 260.0 COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2U6B7@28211|Alphaproteobacteria,43XIQ@69657|Hyphomonadaceae 28211|Alphaproteobacteria S UPF0126 domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - UPF0126 TGS3_k127_3530727_0 1247963.JPHU01000003_gene1445 2.489e-170 547.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2TQT3@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM TGS3_k127_353839_2 377629.TERTU_4322 6.381e-20 91.0 COG4424@1|root,COG4424@2|Bacteria,1N77D@1224|Proteobacteria,1RZKD@1236|Gammaproteobacteria,2PPIB@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_1,Sulfotransfer_3 TGS3_k127_353839_1 1417296.U879_12360 8.583e-97 327.0 COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,2TRZB@28211|Alphaproteobacteria 28211|Alphaproteobacteria M glycosyl transferase - - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 TGS3_k127_353839_0 1280948.HY36_06585 7.119e-111 362.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2TRDH@28211|Alphaproteobacteria,43WRN@69657|Hyphomonadaceae 28211|Alphaproteobacteria D Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system ttcA - - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 TGS3_k127_35687_3 631362.Thi970DRAFT_03532 8.472e-16 87.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,1WXHV@135613|Chromatiales 135613|Chromatiales U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD TGS3_k127_35687_2 1479238.JQMZ01000001_gene1134 6.636e-49 185.0 COG0614@1|root,COG0614@2|Bacteria,1RDZS@1224|Proteobacteria,2U6ZU@28211|Alphaproteobacteria,440RH@69657|Hyphomonadaceae 28211|Alphaproteobacteria P abc-type fe3 -hydroxamate transport system, periplasmic component - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 TGS3_k127_35687_0 1122137.AQXF01000005_gene1274 8.834e-113 386.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2TT3G@28211|Alphaproteobacteria 28211|Alphaproteobacteria H receptor - - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec TGS3_k127_35687_1 314260.PB2503_02887 1.995e-76 269.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,2U17R@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the ompA family - - - - - - - - - - - - OMP_b-brl,OmpA TGS3_k127_3579935_0 1110502.TMO_0886 2.421e-235 741.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2TQUX@28211|Alphaproteobacteria,2JPG1@204441|Rhodospirillales 204441|Rhodospirillales G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate cbbT - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N TGS3_k127_3579935_5 402881.Plav_2110 5.857e-17 84.0 COG3027@1|root,COG3027@2|Bacteria,1N8NY@1224|Proteobacteria,2UCRX@28211|Alphaproteobacteria,1JPGU@119043|Rhodobiaceae 28211|Alphaproteobacteria D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division MA20_17980 - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA TGS3_k127_3579935_2 1177928.TH2_05703 2.29e-91 305.0 COG0778@1|root,COG0778@2|Bacteria,1MY39@1224|Proteobacteria,2TTZC@28211|Alphaproteobacteria,2JW20@204441|Rhodospirillales 204441|Rhodospirillales C Nitroreductase family - - - - - - - - - - - - Nitroreductase TGS3_k127_3579935_4 1117647.M5M_06385 1.398e-17 90.0 2CWKB@1|root,32SZW@2|Bacteria,1RD54@1224|Proteobacteria,1S4QG@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_3579935_1 1247963.JPHU01000001_gene1914 1.44e-227 720.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2TR2M@28211|Alphaproteobacteria 28211|Alphaproteobacteria L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C TGS3_k127_3579935_3 1247963.JPHU01000001_gene1913 2.838e-39 149.0 2C068@1|root,30N9J@2|Bacteria,1REH5@1224|Proteobacteria,2U74G@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3035) - - - - - - - - - - - - DUF3035 TGS3_k127_3584095_0 1247963.JPHU01000005_gene259 1.241e-132 433.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TQRZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yheS - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_Xtn TGS3_k127_3584095_1 648757.Rvan_1583 1.374e-31 126.0 COG1605@1|root,COG1605@2|Bacteria,1PV10@1224|Proteobacteria,2V6I1@28211|Alphaproteobacteria,3N78S@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria E Chorismate mutase, type II - - 4.2.99.21 ko:K04782 ko01053,ko01110,ko01130,map01053,map01110,map01130 - R06602 RC01549,RC02148 ko00000,ko00001,ko01000 - - - CM_2 TGS3_k127_3584095_2 1247963.JPHU01000005_gene289 2.959e-25 110.0 COG2050@1|root,COG2050@2|Bacteria 2|Bacteria Q thiolester hydrolase activity - - - - - - - - - - - - 4HBT,4HBT_3 TGS3_k127_3598165_0 1247963.JPHU01000001_gene1878 6.844e-262 827.0 COG2866@1|root,COG2866@2|Bacteria,1N9W9@1224|Proteobacteria,2U2SA@28211|Alphaproteobacteria 28211|Alphaproteobacteria E carboxypeptidase - - - - - - - - - - - - Peptidase_M14 TGS3_k127_3598165_2 1035191.HMPREF0185_02801 7.234e-125 404.0 COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2TS3H@28211|Alphaproteobacteria,2KFUW@204458|Caulobacterales 204458|Caulobacterales E Belongs to the transferase hexapeptide repeat family dapD - 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,THDPS_N_2 TGS3_k127_3598165_1 1247963.JPHU01000013_gene699 1.11e-179 572.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim TGS3_k127_3598165_4 1247963.JPHU01000013_gene698 4.205e-54 194.0 296B6@1|root,2ZTM2@2|Bacteria,1PBBC@1224|Proteobacteria,2UWTS@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_3598165_3 1247963.JPHU01000013_gene696 1.898e-71 248.0 COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2TU68@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A TGS3_k127_3640701_0 1346791.M529_03385 5.165e-292 910.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TT4X@28211|Alphaproteobacteria,2K0E1@204457|Sphingomonadales 204457|Sphingomonadales S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 TGS3_k127_3640701_3 745310.G432_16720 3.996e-15 81.0 COG4317@1|root,COG4317@2|Bacteria,1N7ZU@1224|Proteobacteria,2UGRZ@28211|Alphaproteobacteria,2K75H@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF1427) - - - - - - - - - - - - DUF1427 TGS3_k127_3640701_1 1207055.C100_14360 4.579e-106 348.0 COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2TU4C@28211|Alphaproteobacteria,2JZXK@204457|Sphingomonadales 28211|Alphaproteobacteria Q Isochorismatase family - - - - - - - - - - - - Isochorismatase TGS3_k127_3640701_4 118166.JH976537_gene4612 8.535e-13 73.0 COG1335@1|root,COG1335@2|Bacteria,1GEWG@1117|Cyanobacteria,1HG9N@1150|Oscillatoriales 1117|Cyanobacteria Q COGs COG1335 Amidase related to nicotinamidase - - - - - - - - - - - - Isochorismatase TGS3_k127_3640701_2 509190.Cseg_2070 1.81e-41 155.0 COG2021@1|root,COG2021@2|Bacteria,1QIH6@1224|Proteobacteria,2TW9Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 TGS3_k127_3642564_18 1550073.JROH01000007_gene1908 1.307e-08 60.0 2FB68@1|root,30QV6@2|Bacteria,1NWWK@1224|Proteobacteria,2US5H@28211|Alphaproteobacteria,2K6YE@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - TGS3_k127_3642564_12 1247963.JPHU01000001_gene1863 1.468e-56 216.0 COG1807@1|root,COG1807@2|Bacteria,1QRMT@1224|Proteobacteria,2TU25@28211|Alphaproteobacteria 28211|Alphaproteobacteria M lipopolysaccharide core region biosynthetic process - GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008378,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - - - - - - - - - - PMT_2 TGS3_k127_3642564_17 314260.PB2503_02772 7.273e-16 83.0 COG0790@1|root,COG0790@2|Bacteria 2|Bacteria S beta-lactamase activity MA20_36515 - - ko:K07126,ko:K13582 ko04112,map04112 - - - ko00000,ko00001 - - - Sel1 TGS3_k127_3642564_1 314260.PB2503_13364 7.282e-236 753.0 COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,1NWAF@1224|Proteobacteria 1224|Proteobacteria T Response regulator, receiver - - 2.7.13.3 ko:K07677,ko:K07679,ko:K20974 ko02020,ko02025,ko02026,ko05133,map02020,map02025,map02026,map05133 M00474,M00477,M00820 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Hpt,PAS_9,Response_reg TGS3_k127_3642564_14 314260.PB2503_13369 6.213e-35 141.0 COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2U76I@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT cheY-homologous receiver domain - - - - - - - - - - - - Response_reg TGS3_k127_3642564_8 314260.PB2503_13374 6.435e-111 372.0 COG2199@1|root,COG4251@1|root,COG3706@2|Bacteria,COG4251@2|Bacteria,1R7HC@1224|Proteobacteria,2TXW4@28211|Alphaproteobacteria 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Response_reg TGS3_k127_3642564_2 314260.PB2503_13379 1.359e-231 735.0 COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2U16R@28211|Alphaproteobacteria 28211|Alphaproteobacteria P TonB-dependent Receptor Plug Domain - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec TGS3_k127_3642564_16 331869.BAL199_24394 2.194e-19 96.0 2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,2UFAQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF4154) - - - - - - - - - - - - DUF4154 TGS3_k127_3642564_11 314260.PB2503_13389 3.297e-67 237.0 COG3916@1|root,COG3916@2|Bacteria,1RG9A@1224|Proteobacteria,2UIWH@28211|Alphaproteobacteria 28211|Alphaproteobacteria QT Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_5 TGS3_k127_3642564_9 1247963.JPHU01000010_gene2268 1.178e-109 357.0 COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2TR5M@28211|Alphaproteobacteria 28211|Alphaproteobacteria OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease TGS3_k127_3642564_3 1381123.AYOD01000005_gene1325 1.863e-228 712.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2TS3R@28211|Alphaproteobacteria,43HVH@69277|Phyllobacteriaceae 28211|Alphaproteobacteria O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX TGS3_k127_3642564_0 266834.SMc01905 0.0 1151.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2TR4E@28211|Alphaproteobacteria,4BAXM@82115|Rhizobiaceae 28211|Alphaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C TGS3_k127_3642564_15 1120956.JHZK01000044_gene1818 3.099e-30 123.0 COG1605@1|root,COG1605@2|Bacteria,1Q4B2@1224|Proteobacteria,2VCUV@28211|Alphaproteobacteria,1JQFU@119043|Rhodobiaceae 28211|Alphaproteobacteria E Chorismate mutase type II - - 4.2.99.21 ko:K04782 ko01053,ko01110,ko01130,map01053,map01110,map01130 - R06602 RC01549,RC02148 ko00000,ko00001,ko01000 - - - CM_2 TGS3_k127_3642564_13 1247963.JPHU01000016_gene1037 2.607e-39 153.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2UC5G@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hupA - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding TGS3_k127_3642564_7 69395.JQLZ01000003_gene449 2.877e-154 500.0 COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,2TRWS@28211|Alphaproteobacteria,2KGRN@204458|Caulobacterales 204458|Caulobacterales E amino acid - - - ko:K03294,ko:K03759 - - - - ko00000,ko02000 2.A.3.2 - - AA_permease_2 TGS3_k127_3642564_5 685778.AORL01000001_gene139 3.651e-159 517.0 COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,2TUHT@28211|Alphaproteobacteria,2K1MW@204457|Sphingomonadales 204457|Sphingomonadales E Acetylornithine deacetylase Succinyl-diaminopimelate - - - - - - - - - - - - M20_dimer,Peptidase_M20,Peptidase_M28 TGS3_k127_3642564_4 1509405.GV67_13525 5.302e-224 701.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,4BA0X@82115|Rhizobiaceae 28211|Alphaproteobacteria C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt TGS3_k127_3642564_6 1472418.BBJC01000001_gene6 4.927e-158 512.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRSU@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c TGS3_k127_3642564_10 1247963.JPHU01000004_gene612 4.032e-70 251.0 COG0658@1|root,COG0658@2|Bacteria,1MUKF@1224|Proteobacteria,2TRD5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S membrane metal-binding protein - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131 TGS3_k127_3647815_7 1082931.KKY_1436 3.069e-06 55.0 2DI3F@1|root,301X7@2|Bacteria,1PU4C@1224|Proteobacteria,2V5W6@28211|Alphaproteobacteria,3N98I@45401|Hyphomicrobiaceae 1082931.KKY_1436|- - - - - - - - - - - - - - - - TGS3_k127_3647815_1 1247963.JPHU01000006_gene136 5.535e-221 697.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.44,6.2.1.48 ko:K00666,ko:K02182,ko:K20034 ko00920,map00920 - R10820 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - AMP-binding,AMP-binding_C TGS3_k127_3647815_2 1177928.TH2_04783 1.973e-157 506.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2JQKF@204441|Rhodospirillales 204441|Rhodospirillales C III protein, CoA-transferase family - - 2.8.3.16 ko:K07749 - - - - ko00000,ko01000 - - - CoA_transf_3 TGS3_k127_3647815_4 1207058.L53_07785 5.416e-24 109.0 2EATF@1|root,334V8@2|Bacteria,1NE2U@1224|Proteobacteria,2UG2E@28211|Alphaproteobacteria,43YFG@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_3647815_3 517722.AEUE01000007_gene363 4.27e-24 105.0 COG1846@1|root,COG1846@2|Bacteria,1RJ4D@1224|Proteobacteria,2U9KA@28211|Alphaproteobacteria,2K8DP@204457|Sphingomonadales 204457|Sphingomonadales K Winged helix DNA-binding domain - - - - - - - - - - - - HTH_34 TGS3_k127_3647815_6 631454.N177_0908 1.858e-07 57.0 2CAZC@1|root,33GV7@2|Bacteria,1Q6SH@1224|Proteobacteria,2VCIG@28211|Alphaproteobacteria,1JPKN@119043|Rhodobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_3647815_5 1280952.HJA_11759 1.616e-16 86.0 2CBEV@1|root,33GQY@2|Bacteria,1NK6C@1224|Proteobacteria,2UMIW@28211|Alphaproteobacteria,43YHX@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_3647815_0 1247963.JPHU01000011_gene790 1.002e-238 745.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2TSJY@28211|Alphaproteobacteria 28211|Alphaproteobacteria H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD TGS3_k127_365631_2 234267.Acid_1533 5.338e-23 105.0 COG2866@1|root,COG2866@2|Bacteria,3Y416@57723|Acidobacteria 57723|Acidobacteria E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 TGS3_k127_365631_1 391937.NA2_14937 1.891e-45 169.0 COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,2U99S@28211|Alphaproteobacteria,43JVJ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Belongs to the UPF0260 family MA20_15575 - - ko:K09160 - - - - ko00000 - - - CxxCxxCC TGS3_k127_365631_0 666685.R2APBS1_1373 8.53e-168 544.0 COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,1RPFW@1236|Gammaproteobacteria,1X4ZQ@135614|Xanthomonadales 135614|Xanthomonadales I Belongs to the type-B carboxylesterase lipase family - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase TGS3_k127_3679975_3 1280944.HY17_05405 1.549e-55 199.0 2ANPA@1|root,31DNS@2|Bacteria,1RHTE@1224|Proteobacteria,2U8XN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - - - - - - - - - - DUF3833 TGS3_k127_3679975_1 1382303.JPOM01000001_gene327 4.205e-86 293.0 COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,2TS11@28211|Alphaproteobacteria,2KG6A@204458|Caulobacterales 204458|Caulobacterales S Belongs to the UPF0246 family - - - ko:K09861 - - - - ko00000 - - - H2O2_YaaD TGS3_k127_3679975_0 59538.XP_005976101.1 2.04e-144 472.0 COG0277@1|root,KOG1232@2759|Eukaryota,38DBR@33154|Opisthokonta,3BFC0@33208|Metazoa,3CYB0@33213|Bilateria,48AJU@7711|Chordata,48X5Y@7742|Vertebrata,3J8XF@40674|Mammalia,4J4TC@91561|Cetartiodactyla 33208|Metazoa C D-2-hydroxyglutarate dehydrogenase - - 1.1.99.39 ko:K18204 - - - - ko00000,ko01000 - - - FAD-oxidase_C,FAD_binding_4 TGS3_k127_3679975_2 1280944.HY17_02475 1.502e-56 215.0 COG4798@1|root,COG4798@2|Bacteria,1RHGZ@1224|Proteobacteria,2U69N@28211|Alphaproteobacteria,43XNX@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_25,PCMT TGS3_k127_3701661_3 1247963.JPHU01000003_gene1345 2.963e-13 77.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2TUI7@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA - 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf TGS3_k127_3701661_0 1380394.JADL01000009_gene3314 7.617e-194 615.0 COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2TQY4@28211|Alphaproteobacteria,2JVFA@204441|Rhodospirillales 204441|Rhodospirillales E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 TGS3_k127_3701661_1 322710.Avin_47830 4.303e-55 205.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate TGS3_k127_3701661_2 1434929.X946_2719 2.309e-26 118.0 COG1741@1|root,COG1741@2|Bacteria,1RA1P@1224|Proteobacteria,2VKQQ@28216|Betaproteobacteria,1K9BN@119060|Burkholderiaceae 28216|Betaproteobacteria S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C TGS3_k127_37196_2 196367.JNFG01000040_gene7971 1.623e-155 504.0 COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,2VI2E@28216|Betaproteobacteria,1K2FI@119060|Burkholderiaceae 28216|Betaproteobacteria C belongs to the aldehyde dehydrogenase family - - 1.2.1.68 ko:K00154 - - - - ko00000,ko01000 - - - Aldedh TGS3_k127_37196_1 1082933.MEA186_04866 9.108e-184 589.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,43N03@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Belongs to the GMC oxidoreductase family MA20_19170 - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N TGS3_k127_37196_0 1120792.JAFV01000001_gene506 3.481e-250 785.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2TQPM@28211|Alphaproteobacteria,36XQP@31993|Methylocystaceae 28211|Alphaproteobacteria M Glutamine amidotransferase domain glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS TGS3_k127_37196_5 1161401.ASJA01000017_gene1285 1.335e-70 252.0 COG2942@1|root,COG2942@2|Bacteria,1PE13@1224|Proteobacteria,2U4P6@28211|Alphaproteobacteria,43XN1@69657|Hyphomonadaceae 28211|Alphaproteobacteria G COG2942 N-acyl-D-glucosamine 2-epimerase MA20_42590 - 5.1.3.8,5.3.1.8 ko:K01787,ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01207,R01819 RC00290,RC00376 ko00000,ko00001,ko00002,ko01000 - - - GlcNAc_2-epim TGS3_k127_37196_4 1382303.JPOM01000001_gene1457 1.337e-91 313.0 COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2TT0R@28211|Alphaproteobacteria,2KGBB@204458|Caulobacterales 204458|Caulobacterales M Belongs to the mannose-6-phosphate isomerase type 2 family - - 2.7.7.13 ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885 RC00002 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase TGS3_k127_37196_3 948106.AWZT01000062_gene4197 3.391e-92 309.0 COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,2VIN9@28216|Betaproteobacteria,1K166@119060|Burkholderiaceae 28216|Betaproteobacteria M udp-glucose 4-epimerase galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd TGS3_k127_3747687_3 314260.PB2503_00782 8.467e-70 245.0 COG0406@1|root,COG0406@2|Bacteria,1R62X@1224|Proteobacteria,2U6T9@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Phosphoglycerate mutase - - - - - - - - - - - - His_Phos_1 TGS3_k127_3747687_2 314260.PB2503_00787 2.714e-142 471.0 COG0457@1|root,COG1876@1|root,COG0457@2|Bacteria,COG1876@2|Bacteria 2|Bacteria M D-alanyl-D-alanine carboxypeptidase yodJ - 3.4.13.22,3.4.16.4,3.4.17.14 ko:K01286,ko:K07260,ko:K18866 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651,M00652 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY TGS3_k127_3747687_0 1333998.M2A_0445 0.0 1368.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,4BP91@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF TGS3_k127_3747687_5 1121948.AUAC01000002_gene943 2.129e-19 90.0 COG2938@1|root,COG2938@2|Bacteria,1N6SJ@1224|Proteobacteria,2UFF5@28211|Alphaproteobacteria,43YF8@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Flavinator of succinate dehydrogenase - - - ko:K09159 - - - - ko00000,ko02048 - - - Sdh5 TGS3_k127_3747687_1 1247963.JPHU01000014_gene1023 3.075e-274 859.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2TR86@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge TGS3_k127_3749243_4 1282876.BAOK01000002_gene539 6.454e-44 163.0 COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,2TRZV@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Protein of unknown function (DUF1298) - - - - - - - - - - - - DUF1298,WES_acyltransf TGS3_k127_3749243_2 1545915.JROG01000003_gene880 3.654e-97 324.0 COG1075@1|root,COG1075@2|Bacteria,1NJNA@1224|Proteobacteria,2TSQC@28211|Alphaproteobacteria,2K23V@204457|Sphingomonadales 204457|Sphingomonadales S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 TGS3_k127_3749243_0 745310.G432_04415 1.108e-117 385.0 COG1018@1|root,COG1018@2|Bacteria,1MW37@1224|Proteobacteria,2TVXU@28211|Alphaproteobacteria,2KE9M@204457|Sphingomonadales 204457|Sphingomonadales C Oxidoreductase FAD-binding domain - - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - FAD_binding_6,NAD_binding_1 TGS3_k127_3749243_3 1502851.FG93_02182 1.318e-66 235.0 COG1207@1|root,COG1207@2|Bacteria,1RD3B@1224|Proteobacteria,2U7K3@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Bacterial transferase hexapeptide (six repeats) - - - - - - - - - - - - Hexapep TGS3_k127_3749243_5 314260.PB2503_06932 5.066e-36 143.0 COG3428@1|root,COG3428@2|Bacteria,1N9PB@1224|Proteobacteria,2TUD0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacterial PH domain - - - - - - - - - - - - bPH_2 TGS3_k127_3749243_1 314260.PB2503_06952 1.284e-101 337.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains chvD - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_Xtn TGS3_k127_3761294_2 314260.PB2503_08144 2.366e-75 254.0 COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2TRTZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain ragA GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C TGS3_k127_3761294_0 1247963.JPHU01000008_gene2781 1.471e-104 356.0 COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1MW8M@1224|Proteobacteria,2TUSJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA TGS3_k127_3761294_1 1101191.KI912577_gene173 4.034e-80 281.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2TRY7@28211|Alphaproteobacteria,1JQX0@119045|Methylobacteriaceae 28211|Alphaproteobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE TGS3_k127_3777488_1 1280949.HAD_04825 2.16e-83 282.0 COG1680@1|root,COG1680@2|Bacteria,1N6AK@1224|Proteobacteria,2UDQC@28211|Alphaproteobacteria 28211|Alphaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase TGS3_k127_3777488_0 383381.EH30_04355 1.535e-224 707.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRA0@28211|Alphaproteobacteria,2K0B0@204457|Sphingomonadales 28211|Alphaproteobacteria I acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - 6.4.1.5 ko:K13778 ko00281,map00281 - R03494 RC00367,RC00942 ko00000,ko00001,ko01000 - - - Carboxyl_trans TGS3_k127_3777488_2 314287.GB2207_00975 1.005e-57 210.0 COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,1J9KH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I enoyl-CoA hydratase atuE - 4.2.1.57 ko:K13779 ko00281,map00281 - R03493 RC00941 ko00000,ko00001,ko01000 - - - ECH_1 TGS3_k127_3777488_3 1223521.BBJX01000006_gene1749 3.25e-55 197.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2VJHH@28216|Betaproteobacteria,4AC5B@80864|Comamonadaceae 28216|Betaproteobacteria I Carbamoyl-phosphate synthase L chain, ATP-binding - - 6.4.1.5 ko:K13777 ko00281,map00281 - R03494 RC00367,RC00942 ko00000,ko00001,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 TGS3_k127_3793384_4 1247963.JPHU01000002_gene2752 2.391e-83 281.0 COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,2TSK7@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain regA GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - ko:K15012 ko02020,map02020 M00523 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg TGS3_k127_3793384_3 402881.Plav_0017 2.835e-116 389.0 COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,2TSS0@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase regB - 2.7.13.3 ko:K15011 ko02020,map02020 M00523 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA TGS3_k127_3793384_6 1247963.JPHU01000002_gene2750 5.542e-51 187.0 COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2U0Q3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC TGS3_k127_3793384_5 246200.SPOA0272a 1.455e-68 237.0 2D579@1|root,32TID@2|Bacteria,1RH2N@1224|Proteobacteria,2U9TR@28211|Alphaproteobacteria,4NDCR@97050|Ruegeria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_3793384_0 1479238.JQMZ01000001_gene593 1.846e-173 553.0 COG4553@1|root,COG4553@2|Bacteria,1MVUH@1224|Proteobacteria,2TQXW@28211|Alphaproteobacteria,43WQT@69657|Hyphomonadaceae 28211|Alphaproteobacteria I COG4553 Poly-beta-hydroxyalkanoate depolymerase phaZ - 3.1.1.75 ko:K05973 ko00650,map00650 - R05118 - ko00000,ko00001,ko01000 - - - PHB_depo_C TGS3_k127_3793384_7 1121123.AUAO01000003_gene2490 0.0001455 52.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,2U17R@28211|Alphaproteobacteria,2KFB3@204458|Caulobacterales 204458|Caulobacterales M Belongs to the ompA family - - - - - - - - - - - - OMP_b-brl,OmpA TGS3_k127_3793384_1 1247963.JPHU01000002_gene2664 1.372e-169 537.0 COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2TSV6@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Catalyzes the reversible oxidation of malate to oxaloacetate mdh GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N TGS3_k127_3793384_2 1121439.dsat_0564 1.201e-149 484.0 COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42MFI@68525|delta/epsilon subdivisions,2WKXD@28221|Deltaproteobacteria,2MAH6@213115|Desulfovibrionales 28221|Deltaproteobacteria S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 TGS3_k127_3829165_3 1449049.JONW01000010_gene3744 2.427e-14 82.0 COG4773@1|root,COG4773@2|Bacteria,1NXPR@1224|Proteobacteria,2U161@28211|Alphaproteobacteria,2KICT@204458|Caulobacterales 204458|Caulobacterales P TonB-dependent Receptor Plug - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec TGS3_k127_3829165_0 1183438.GKIL_2549 4.479e-107 360.0 COG2957@1|root,COG2957@2|Bacteria,1G1FA@1117|Cyanobacteria 1117|Cyanobacteria E Belongs to the agmatine deiminase family - - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph TGS3_k127_3829165_2 1532558.JL39_06130 2.867e-22 99.0 COG0640@1|root,COG0640@2|Bacteria,1N10H@1224|Proteobacteria,2UBRH@28211|Alphaproteobacteria,4BEJV@82115|Rhizobiaceae 28211|Alphaproteobacteria K transcriptional regulators - - - - - - - - - - - - HTH_20 TGS3_k127_3829165_1 1280948.HY36_01155 5.29e-65 228.0 COG0225@1|root,COG0225@2|Bacteria,1NC84@1224|Proteobacteria,2TTDD@28211|Alphaproteobacteria,43XTD@69657|Hyphomonadaceae 28211|Alphaproteobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR TGS3_k127_3848455_0 1247963.JPHU01000005_gene339 1.358e-232 726.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2TRSR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Modulator of DNA gyrase tldD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD TGS3_k127_3848455_1 633149.Bresu_1603 5.16e-19 96.0 COG1309@1|root,COG1309@2|Bacteria,1N855@1224|Proteobacteria 1224|Proteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N TGS3_k127_386204_1 571166.KI421509_gene2150 1.4e-101 346.0 COG2124@1|root,COG2124@2|Bacteria,1RAN9@1224|Proteobacteria,2U0X8@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Cytochrome P450 - - - ko:K21033 - - - - ko00000,ko00199 - - - p450 TGS3_k127_386204_2 1267005.KB911256_gene1935 8.595e-71 246.0 COG1381@1|root,COG1381@2|Bacteria,1MVEJ@1224|Proteobacteria,2TTYW@28211|Alphaproteobacteria,3N6R2@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N TGS3_k127_386204_3 883080.HMPREF9697_00019 1.476e-57 213.0 2DBIF@1|root,2Z9FG@2|Bacteria,1QYR5@1224|Proteobacteria,2TTVX@28211|Alphaproteobacteria,3JXU6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_386204_0 1247963.JPHU01000003_gene1325 0.0 1094.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2TQRQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV TGS3_k127_386208_1 95619.PM1_0222135 3.982e-99 328.0 COG0446@1|root,COG3453@1|root,COG0446@2|Bacteria,COG3453@2|Bacteria,1N5MC@1224|Proteobacteria,1RQS1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S oxidoreductase sqrdl - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - DUF442,Pyr_redox_2 TGS3_k127_386208_0 1122929.KB908218_gene1492 2.611e-210 669.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0659 Sulfate permease and related transporters (MFS superfamily - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp TGS3_k127_386208_2 187272.Mlg_2790 1.625e-83 286.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1WWI2@135613|Chromatiales 135613|Chromatiales IQ PFAM AMP-dependent synthetase and ligase - - 6.2.1.3 ko:K01897,ko:K18661 ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280,R03383 RC00004,RC00014,RC00137 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C TGS3_k127_3906598_7 1248760.ANFZ01000002_gene3157 1.776e-20 100.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,2U997@28211|Alphaproteobacteria,2K4GS@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the UPF0178 family - - - ko:K09768 - - - - ko00000 - - - DUF188 TGS3_k127_3906598_1 46429.BV95_03304 3.052e-117 391.0 COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TTRR@28211|Alphaproteobacteria,2KCSW@204457|Sphingomonadales 204457|Sphingomonadales C Cytochrome P450 - - - - - - - - - - - - p450 TGS3_k127_3906598_3 394221.Mmar10_1145 4.102e-61 216.0 29KMP@1|root,307IZ@2|Bacteria,1REJ6@1224|Proteobacteria,2UAW7@28211|Alphaproteobacteria,43XXB@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF4287) - - - - - - - - - - - - DUF4287 TGS3_k127_3906598_5 1280950.HJO_07847 7.257e-45 170.0 COG3832@1|root,COG3832@2|Bacteria,1Q4JU@1224|Proteobacteria,2V6I0@28211|Alphaproteobacteria,43ZSQ@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 TGS3_k127_3906598_6 394221.Mmar10_1143 3.617e-35 140.0 COG0640@1|root,COG0640@2|Bacteria,1RIJ9@1224|Proteobacteria,2UVS4@28211|Alphaproteobacteria,4411C@69657|Hyphomonadaceae 28211|Alphaproteobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 TGS3_k127_3906598_4 1161401.ASJA01000014_gene1075 4.353e-56 210.0 COG2207@1|root,COG2207@2|Bacteria,1P4M5@1224|Proteobacteria,2U37A@28211|Alphaproteobacteria 28211|Alphaproteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 TGS3_k127_3906598_2 509190.Cseg_2307 1.995e-84 290.0 COG3000@1|root,COG3000@2|Bacteria,1QSZU@1224|Proteobacteria,2VG1S@28211|Alphaproteobacteria,2KJBP@204458|Caulobacterales 204458|Caulobacterales I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase TGS3_k127_3906598_0 1313172.YM304_34560 2.998e-135 443.0 COG3670@1|root,COG3670@2|Bacteria,2GK7D@201174|Actinobacteria 201174|Actinobacteria Q dioxygenase - - - ko:K11159 - - - - ko00000 - - - RPE65 TGS3_k127_3908292_3 1411123.JQNH01000001_gene2143 6.4e-28 115.0 COG0524@1|root,COG0524@2|Bacteria,1MWX4@1224|Proteobacteria,2VF16@28211|Alphaproteobacteria 28211|Alphaproteobacteria G belongs to the carbohydrate kinase PfkB family - - - - - - - - - - - - PfkB TGS3_k127_3908292_1 411684.HPDFL43_17126 5.514e-149 478.0 COG3684@1|root,COG3684@2|Bacteria,1QZI3@1224|Proteobacteria,2U07T@28211|Alphaproteobacteria,43RGP@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G DeoC/LacD family aldolase MA20_09915 - 4.1.2.40,4.1.2.57 ko:K01635,ko:K01671 ko00052,ko01100,ko02024,map00052,map01100,map02024 - R01069,R10760 RC00438,RC00439 ko00000,ko00001,ko01000 - - - DeoC TGS3_k127_3908292_2 1547437.LL06_24220 5.352e-148 483.0 COG2407@1|root,COG2407@2|Bacteria,1R8S2@1224|Proteobacteria,2VEQ1@28211|Alphaproteobacteria,43IX2@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Catalyzes the conversion of L-arabinose to L-ribulose - - - - - - - - - - - - Fucose_iso_C TGS3_k127_3908292_0 983545.Glaag_1462 6.325e-237 747.0 COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,1RMJ9@1236|Gammaproteobacteria,4679Q@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 31 family yicI GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0016787,GO:0016798,GO:0042802,GO:0080176 3.2.1.177 ko:K01811 - - - - ko00000,ko01000 - GH31 - Gal_mutarotas_2,Glyco_hydro_31 TGS3_k127_3915945_1 1248917.ANFX01000022_gene666 4.284e-188 595.0 COG0365@1|root,COG0604@1|root,COG1024@1|root,COG0365@2|Bacteria,COG0604@2|Bacteria,COG1024@2|Bacteria,1MXIK@1224|Proteobacteria,2U43I@28211|Alphaproteobacteria,2K2UF@204457|Sphingomonadales 204457|Sphingomonadales CI Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ADH_zinc_N,AMP-binding,AMP-binding_C,ECH_1 TGS3_k127_3915945_0 1248917.ANFX01000022_gene667 0.0 1379.0 COG1028@1|root,COG1028@2|Bacteria,1R6F3@1224|Proteobacteria,2U1Z9@28211|Alphaproteobacteria,2K0Y6@204457|Sphingomonadales 204457|Sphingomonadales IQ KR domain - - - - - - - - - - - - adh_short,adh_short_C2 TGS3_k127_3915945_2 1114964.L485_07490 1.131e-08 56.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TS4W@28211|Alphaproteobacteria,2KEEP@204457|Sphingomonadales 204457|Sphingomonadales P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec TGS3_k127_3934059_4 1247963.JPHU01000005_gene290 1.135e-19 94.0 COG2050@1|root,COG2050@2|Bacteria 2|Bacteria Q thiolester hydrolase activity yigI - - - - - - - - - - - 4HBT TGS3_k127_3934059_1 501479.ACNW01000048_gene353 1.668e-91 311.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2TST5@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0530 Ca2 Na antiporter - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex TGS3_k127_3934059_2 314260.PB2503_10704 7.253e-68 245.0 COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2TUNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria DM COG0739 Membrane proteins related to metalloendopeptidases nlpD - - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 TGS3_k127_3934059_0 1123503.KB908058_gene1013 1.515e-98 327.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2TQXZ@28211|Alphaproteobacteria,2KFJK@204458|Caulobacterales 204458|Caulobacterales S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE TGS3_k127_3934059_3 983920.Y88_2407 2.657e-44 162.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2TR4T@28211|Alphaproteobacteria,2K0IX@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b TGS3_k127_3965913_0 1121861.KB899911_gene1169 3.856e-127 415.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2TQNE@28211|Alphaproteobacteria,2JPV4@204441|Rhodospirillales 204441|Rhodospirillales H Belongs to the prokaryotic GSH synthase family gshB - 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N TGS3_k127_3965913_2 1247963.JPHU01000003_gene1429 1.622e-30 128.0 COG2823@1|root,COG2823@2|Bacteria,1NJK0@1224|Proteobacteria,2U9XB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S periplasmic or secreted lipoprotein osmY - - - - - - - - - - - BON TGS3_k127_3965913_3 1247963.JPHU01000003_gene1428 1.325e-25 112.0 COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2UFTM@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the UPF0102 family MA20_24645 - - ko:K07460 - - - - ko00000 - - - UPF0102 TGS3_k127_3965913_1 685778.AORL01000010_gene3167 2.541e-86 294.0 COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2TR14@28211|Alphaproteobacteria,2K0AW@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase TGS3_k127_3970831_1 1385517.N800_00830 7.939e-91 308.0 COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1RS3D@1236|Gammaproteobacteria,1XC2W@135614|Xanthomonadales 135614|Xanthomonadales S VIT family - - - - - - - - - - - - VIT1 TGS3_k127_3970831_0 1161401.ASJA01000008_gene1710 6.503e-228 722.0 COG1228@1|root,COG1228@2|Bacteria,1PS8Y@1224|Proteobacteria,2TQUK@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q amidohydrolase - - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 TGS3_k127_3999041_1 1537715.JQFJ01000002_gene1344 2.424e-24 119.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TS4W@28211|Alphaproteobacteria,2KEEP@204457|Sphingomonadales 204457|Sphingomonadales P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec TGS3_k127_3999041_0 745310.G432_18105 4.468e-66 237.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TS4W@28211|Alphaproteobacteria,2KEEP@204457|Sphingomonadales 204457|Sphingomonadales P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec TGS3_k127_4002140_0 1123060.JONP01000009_gene2156 2.538e-96 325.0 COG0438@1|root,COG0438@2|Bacteria,1PEWW@1224|Proteobacteria,2U2ZQ@28211|Alphaproteobacteria,2JQDK@204441|Rhodospirillales 204441|Rhodospirillales M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 TGS3_k127_4002140_2 1292034.OR37_01414 2.567e-07 63.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2UG4B@28211|Alphaproteobacteria,2KHVC@204458|Caulobacterales 204458|Caulobacterales E Putative esterase - - - - - - - - - - - - Peptidase_S9 TGS3_k127_4002140_1 509190.Cseg_3228 1.906e-17 95.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2TUZZ@28211|Alphaproteobacteria,2KFCI@204458|Caulobacterales 204458|Caulobacterales E Prolyl oligopeptidase - - - - - - - - - - - - Peptidase_S9 TGS3_k127_4004882_1 1247963.JPHU01000007_gene1637 2.71e-232 728.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TRFY@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase TGS3_k127_4004882_6 1247963.JPHU01000007_gene1636 2.355e-35 137.0 COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2UBSZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln TGS3_k127_4004882_5 1125973.JNLC01000016_gene2732 3.182e-54 200.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2U98Y@28211|Alphaproteobacteria,3JVCJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ruvX GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX TGS3_k127_4004882_3 1123072.AUDH01000004_gene678 9.457e-90 306.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2TRHP@28211|Alphaproteobacteria,2JPQQ@204441|Rhodospirillales 204441|Rhodospirillales F Belongs to the ATCase OTCase family pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N TGS3_k127_4004882_4 1161401.ASJA01000018_gene1233 1.823e-70 245.0 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2U7BZ@28211|Alphaproteobacteria,43XKZ@69657|Hyphomonadaceae 28211|Alphaproteobacteria I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf TGS3_k127_4004882_2 1382303.JPOM01000001_gene938 1.416e-109 368.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2TRQE@28211|Alphaproteobacteria,2KEZD@204458|Caulobacterales 204458|Caulobacterales LU DNA protecting protein DprA - - - ko:K04096 - - - - ko00000 - - - DNA_processg_A TGS3_k127_4004882_0 314260.PB2503_10279 0.0 1145.0 COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom TGS3_k127_4004882_7 228410.NE2115 7.977e-05 49.0 COG2161@1|root,COG2161@2|Bacteria,1NCZN@1224|Proteobacteria,2WBVI@28216|Betaproteobacteria,373T3@32003|Nitrosomonadales 28216|Betaproteobacteria D Antitoxin component of a toxin-antitoxin (TA) module - - - - - - - - - - - - PhdYeFM_antitox TGS3_k127_4011168_2 314265.R2601_15417 6.949e-16 85.0 COG0419@1|root,COG0419@2|Bacteria,1MWCT@1224|Proteobacteria,2TS61@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Domain of unknown function (DUF4175) - - - - - - - - - - - - DUF4175 TGS3_k127_4011168_0 1121106.JQKB01000020_gene1978 3.79e-143 466.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2TUFB@28211|Alphaproteobacteria,2JT4S@204441|Rhodospirillales 204441|Rhodospirillales U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF TGS3_k127_4011168_1 509190.Cseg_3228 4.089e-76 264.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2TUZZ@28211|Alphaproteobacteria,2KFCI@204458|Caulobacterales 204458|Caulobacterales E Prolyl oligopeptidase - - - - - - - - - - - - Peptidase_S9 TGS3_k127_4019074_0 1500893.JQNB01000001_gene1855 1.484e-147 471.0 COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,1RP89@1236|Gammaproteobacteria,1X3IN@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N TGS3_k127_4019074_5 237368.SCABRO_00545 5.805e-16 81.0 COG4634@1|root,COG4634@2|Bacteria,2J4DQ@203682|Planctomycetes 2|Bacteria - - - - - - - - - - - - - - - TGS3_k127_4019074_6 258594.RPA2820 2.654e-14 79.0 COG2442@1|root,COG2442@2|Bacteria,1NFPU@1224|Proteobacteria,2UMF4@28211|Alphaproteobacteria,3K53V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF433) - - - - - - - - - - - - DUF433 TGS3_k127_4019074_3 59538.XP_005981811.1 1.455e-68 239.0 COG0221@1|root,KOG1681@1|root,KOG1626@2759|Eukaryota,KOG1681@2759|Eukaryota,38TRP@33154|Opisthokonta,3BCWE@33208|Metazoa,3CZK6@33213|Bilateria,481G7@7711|Chordata,490Y7@7742|Vertebrata,3JEJ8@40674|Mammalia,4J3VF@91561|Cetartiodactyla 33208|Metazoa I delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 - ko:K12663 ko04146,map04146 - - - ko00000,ko00001,ko01000 - - - ECH_1 TGS3_k127_4019074_1 190650.CC_0960 8.313e-134 437.0 COG1228@1|root,COG1228@2|Bacteria,1MUYR@1224|Proteobacteria,2TSA1@28211|Alphaproteobacteria,2KFRA@204458|Caulobacterales 204458|Caulobacterales Q Imidazolone-5-propionate hydrolase hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1,Amidohydro_3 TGS3_k127_4019074_2 1121123.AUAO01000006_gene1899 7.044e-107 354.0 COG0010@1|root,COG0010@2|Bacteria 2|Bacteria E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines hutG - 3.5.3.11,3.5.3.8 ko:K01479,ko:K01480 ko00330,ko00340,ko01100,map00330,map00340,map01100 M00045,M00133 R01157,R02285 RC00024,RC00221,RC00329,RC00681 ko00000,ko00001,ko00002,ko01000 - - - Arginase TGS3_k127_4019074_4 1247963.JPHU01000012_gene871 1.986e-61 226.0 COG2207@1|root,COG2207@2|Bacteria,1RE6R@1224|Proteobacteria,2UB4P@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 TGS3_k127_4026055_2 573370.DMR_15710 1.101e-24 108.0 28MI1@1|root,2ZAUV@2|Bacteria,1R8Y2@1224|Proteobacteria,42UVH@68525|delta/epsilon subdivisions,2WQUU@28221|Deltaproteobacteria,2MFCJ@213115|Desulfovibrionales 28221|Deltaproteobacteria S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii TGS3_k127_4026055_4 1177928.TH2_19093 7.176e-07 53.0 COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,2TRJG@28211|Alphaproteobacteria,2JR42@204441|Rhodospirillales 204441|Rhodospirillales S SpoVR like protein - - - ko:K06415 - - - - ko00000 - - - SpoVR TGS3_k127_4026055_1 1247963.JPHU01000003_gene1501 2.384e-193 611.0 COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,2TTWI@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the UPF0229 family - - - ko:K09786 - - - - ko00000 - - - DUF444 TGS3_k127_4026055_0 314260.PB2503_07217 0.0 1148.0 COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,2TTW4@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Serine protein kinase yeaG - - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA TGS3_k127_4026055_3 314260.PB2503_10049 1.623e-10 62.0 COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2U9WD@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Belongs to the phosphoglycerate mutase family gpmB - 5.4.2.12 ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 TGS3_k127_4042412_1 1247963.JPHU01000013_gene702 3.312e-95 323.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG1520 FOG WD40-like repeat bamB - - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 TGS3_k127_4042412_7 1430440.MGMSRv2_0529 3.872e-19 98.0 COG4649@1|root,COG4649@2|Bacteria,1P2GI@1224|Proteobacteria,2UCFZ@28211|Alphaproteobacteria,2JTGD@204441|Rhodospirillales 204441|Rhodospirillales S Tetratricopeptide repeat-like domain - - - - - - - - - - - - TPR_21 TGS3_k127_4042412_0 1121949.AQXT01000002_gene463 2.694e-116 382.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2TQT1@28211|Alphaproteobacteria,43WN5@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf TGS3_k127_4042412_5 1292034.OR37_03987 5.791e-47 175.0 COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,2U723@28211|Alphaproteobacteria,2KGF7@204458|Caulobacterales 204458|Caulobacterales M Lipocalin-like domain - - - ko:K03098 - - - - ko00000,ko04147 - - - Lipocalin_2 TGS3_k127_4042412_10 485915.Dret_2345 0.00038 51.0 COG3103@1|root,COG4520@1|root,COG4520@2|Bacteria,COG4991@2|Bacteria,1ND2D@1224|Proteobacteria,4304Y@68525|delta/epsilon subdivisions,2WV4X@28221|Deltaproteobacteria,2MBW8@213115|Desulfovibrionales 28221|Deltaproteobacteria M surface antigen - - - - - - - - - - - - Rick_17kDa_Anti,SH3_3 TGS3_k127_4042412_2 1282876.BAOK01000001_gene2621 5.835e-73 261.0 COG5330@1|root,COG5330@2|Bacteria,1R3VY@1224|Proteobacteria,2TUQ8@28211|Alphaproteobacteria,4BRQJ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Uncharacterised protein conserved in bacteria (DUF2336) - - - - - - - - - - - - DUF2336 TGS3_k127_4042412_9 936455.KI421499_gene553 0.0003352 48.0 2EFX8@1|root,339PG@2|Bacteria,1N5SD@1224|Proteobacteria,2UDQ9@28211|Alphaproteobacteria,3K5WH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_4042412_8 1382303.JPOM01000001_gene203 3.064e-18 88.0 COG5447@1|root,COG5447@2|Bacteria,1N1KU@1224|Proteobacteria,2UCBQ@28211|Alphaproteobacteria,2KGTT@204458|Caulobacterales 204458|Caulobacterales S Protein of unknown function (DUF1491) - - - - - - - - - - - - DUF1491 TGS3_k127_4042412_3 1247963.JPHU01000005_gene329 1.72e-52 204.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TSRP@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase divJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K07716,ko:K11357 ko02020,ko04112,map02020,map04112 M00511 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4 TGS3_k127_4042412_4 1247963.JPHU01000005_gene330 3.155e-48 187.0 28NKZ@1|root,32ZMF@2|Bacteria,1NCCR@1224|Proteobacteria,2UFA7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_4042412_6 909943.HIMB100_00012840 2.069e-28 117.0 COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,2U9D3@28211|Alphaproteobacteria,4BQJU@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S protein conserved in bacteria - - - ko:K09966 - - - - ko00000 - - - DUF2237 TGS3_k127_4042959_5 1121948.AUAC01000006_gene533 6.705e-59 211.0 COG1309@1|root,COG1309@2|Bacteria,1R52P@1224|Proteobacteria,2UDA0@28211|Alphaproteobacteria,43XZP@69657|Hyphomonadaceae 28211|Alphaproteobacteria K COG1309 Transcriptional regulator - - - - - - - - - - - - TetR,TetR_N TGS3_k127_4042959_1 1110502.TMO_0123 1.112e-122 397.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2TR4J@28211|Alphaproteobacteria,2JPSB@204441|Rhodospirillales 204441|Rhodospirillales C Electron transfer flavoprotein, beta subunit etfB - - ko:K03521 - - - - ko00000 - - - ETF TGS3_k127_4042959_0 935261.JAGL01000019_gene535 1.169e-127 418.0 COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,2TR10@28211|Alphaproteobacteria,43HMB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Electron transfer flavoprotein etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha TGS3_k127_4042959_6 1161401.ASJA01000033_gene3051 3.479e-58 210.0 28NUB@1|root,2ZBSR@2|Bacteria,1RKP1@1224|Proteobacteria,2V8F0@28211|Alphaproteobacteria,43ZTB@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_4042959_11 1007104.SUS17_1979 3.982e-41 161.0 COG0789@1|root,COG0789@2|Bacteria,1MWN0@1224|Proteobacteria,2UCJC@28211|Alphaproteobacteria,2K3X8@204457|Sphingomonadales 204457|Sphingomonadales K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1,TipAS TGS3_k127_4042959_8 394221.Mmar10_1374 1.395e-50 185.0 2CVTP@1|root,32SY9@2|Bacteria,1N209@1224|Proteobacteria,2UC8J@28211|Alphaproteobacteria,43YQI@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1203) - - - - - - - - - - - - DUF1203 TGS3_k127_4042959_13 1116369.KB890024_gene2402 2.633e-22 97.0 COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,2UKPX@28211|Alphaproteobacteria,43QUB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Dodecin - - - ko:K09165 - - - - ko00000 - - - Dodecin TGS3_k127_4042959_3 314260.PB2503_06482 2.979e-95 332.0 COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,2UAC1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16,TPR_7,TPR_8 TGS3_k127_4042959_7 1415779.JOMH01000001_gene2431 2.409e-54 197.0 COG0810@1|root,COG0810@2|Bacteria,1R4VE@1224|Proteobacteria,1RN5E@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG0810 Periplasmic protein TonB, links inner and outer membranes - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C TGS3_k127_4042959_10 1415779.JOMH01000001_gene2432 8.723e-42 159.0 COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S7FH@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD TGS3_k127_4042959_12 1247963.JPHU01000008_gene2852 2.708e-40 153.0 COG0848@1|root,COG0848@2|Bacteria,1RHQ3@1224|Proteobacteria 1224|Proteobacteria U biopolymer transport protein - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD TGS3_k127_4042959_9 1123503.KB908058_gene890 6.876e-43 162.0 COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,2UAB1@28211|Alphaproteobacteria 28211|Alphaproteobacteria U TonB system transport protein ExbB - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB TGS3_k127_4042959_2 1415779.JOMH01000001_gene2435 1.03e-121 406.0 COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,1XCFT@135614|Xanthomonadales 135614|Xanthomonadales U MotA/TolQ/ExbB proton channel family - - - - - - - - - - - - MotA_ExbB TGS3_k127_4042959_4 1415779.JOMH01000001_gene2436 8.768e-64 228.0 COG1196@1|root,COG1196@2|Bacteria,1NGHR@1224|Proteobacteria,1RQW7@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Protein of unknown function (DUF3450) - - - - - - - - - - - - DUF3450 TGS3_k127_4056081_2 1198114.AciX9_1861 1.347e-99 338.0 COG0438@1|root,COG0438@2|Bacteria,3Y97K@57723|Acidobacteria,2JNH3@204432|Acidobacteriia 204432|Acidobacteriia M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 TGS3_k127_4056081_0 1247963.JPHU01000001_gene1769 2.445e-150 491.0 COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2TUKE@28211|Alphaproteobacteria 28211|Alphaproteobacteria C transmembrane protein EpsH - - - - - - - - - - - - DUF3485,Exosortase_EpsH TGS3_k127_4056081_1 1479238.JQMZ01000001_gene1482 6.036e-107 366.0 COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,2UBC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 TGS3_k127_4061927_0 384765.SIAM614_03316 9.682e-96 321.0 COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2TQJB@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA TGS3_k127_4061927_2 358220.C380_16335 1.257e-18 87.0 COG4338@1|root,COG4338@2|Bacteria,1NGIS@1224|Proteobacteria 1224|Proteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF2256 TGS3_k127_4061927_1 1379698.RBG1_1C00001G0518 3.479e-26 124.0 COG0515@1|root,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria 2|Bacteria T Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase,TPR_2,TPR_8 TGS3_k127_4069022_1 394221.Mmar10_2170 9.814e-46 170.0 COG3812@1|root,COG3812@2|Bacteria,1RGUV@1224|Proteobacteria,2U9BA@28211|Alphaproteobacteria,43Y6M@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF1993) - - - ko:K09983 - - - - ko00000 - - - DUF1993 TGS3_k127_4069022_2 1247963.JPHU01000011_gene796 2.647e-44 166.0 COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2U72X@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Belongs to the low molecular weight phosphotyrosine protein phosphatase family ptpA - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc TGS3_k127_4069022_3 331869.BAL199_14155 3.257e-40 161.0 COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2U7FV@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ligT - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase TGS3_k127_4069022_0 1353528.DT23_14160 1.806e-62 221.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2TRDY@28211|Alphaproteobacteria,2XM36@285107|Thioclava 28211|Alphaproteobacteria GM COG0451 Nucleoside-diphosphate-sugar epimerases - - - - - - - - - - - - Epimerase TGS3_k127_4069813_7 1121949.AQXT01000002_gene21 2.006e-17 95.0 2AN0E@1|root,31CXN@2|Bacteria,1PVTD@1224|Proteobacteria,2V71X@28211|Alphaproteobacteria,43YWH@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_4069813_3 1161401.ASJA01000009_gene1793 6.301e-48 185.0 28N2A@1|root,2ZB84@2|Bacteria,1R8N1@1224|Proteobacteria,2U7C7@28211|Alphaproteobacteria,43YG8@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - MA20_35720 - - - - - - - - - - - - TGS3_k127_4069813_1 1247963.JPHU01000003_gene1275 1.738e-172 553.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 TGS3_k127_4069813_5 1217720.ALOX01000054_gene2246 4.379e-36 139.0 2CC0C@1|root,32RUG@2|Bacteria,1MZVQ@1224|Proteobacteria,2UBWU@28211|Alphaproteobacteria,2JXTJ@204441|Rhodospirillales 204441|Rhodospirillales S Protein of unknown function (DUF3297) - - - - - - - - - - - - DUF3297 TGS3_k127_4069813_6 1411123.JQNH01000001_gene9 1.846e-34 141.0 COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2TR0C@28211|Alphaproteobacteria 28211|Alphaproteobacteria CO COG0526 Thiol-disulfide isomerase and thioredoxins tlpA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - AhpC-TSA,Redoxin TGS3_k127_4069813_0 1449049.JONW01000012_gene259 4.059e-183 584.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2TR4H@28211|Alphaproteobacteria,2KFRS@204458|Caulobacterales 204458|Caulobacterales E argininosuccinate lyase argH - 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 TGS3_k127_4069813_2 1121033.AUCF01000001_gene2443 2.499e-134 448.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,2JQAX@204441|Rhodospirillales 204441|Rhodospirillales V ABC-type multidrug transport system, ATPase and permease msbA - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran TGS3_k127_4069813_4 1282360.ABAC460_18920 9.043e-45 167.0 COG2365@1|root,COG2365@2|Bacteria,1REIM@1224|Proteobacteria,2TVG9@28211|Alphaproteobacteria,2KFK6@204458|Caulobacterales 204458|Caulobacterales T Protein tyrosine serine phosphatase - - - - - - - - - - - - DUF442 TGS3_k127_4072542_7 1247963.JPHU01000003_gene1287 1.242e-59 212.0 COG2941@1|root,COG2941@2|Bacteria,1RAK4@1224|Proteobacteria,2U85I@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol coq7 - - ko:K06134 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00128 R04984,R08775 RC01254 ko00000,ko00001,ko00002,ko01000 - - - COQ7 TGS3_k127_4072542_0 1234595.C725_2359 3.419e-237 750.0 COG1164@1|root,COG1164@2|Bacteria,1MWYN@1224|Proteobacteria,2TR6R@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Angiotensin-converting enzyme - - 3.4.15.1 ko:K01283 ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - Peptidase_M2 TGS3_k127_4072542_6 69395.JQLZ01000009_gene1953 3.048e-61 217.0 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2U765@28211|Alphaproteobacteria,2KGDA@204458|Caulobacterales 204458|Caulobacterales H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE - 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE TGS3_k127_4072542_5 1408419.JHYG01000002_gene1118 1.807e-62 226.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2TS99@28211|Alphaproteobacteria,2JPBD@204441|Rhodospirillales 204441|Rhodospirillales E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N TGS3_k127_4072542_11 1247963.JPHU01000002_gene2737 1.598e-47 178.0 COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2U9H5@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Maf-like protein maf - - ko:K06287 - - - - ko00000 - - - Maf TGS3_k127_4072542_3 1247963.JPHU01000002_gene2736 2.374e-111 368.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2TT66@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation MA20_24795 - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase TGS3_k127_4072542_2 1247963.JPHU01000002_gene2735 2.576e-114 378.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2TQQV@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D TGS3_k127_4072542_10 1123503.KB908056_gene2086 6.569e-50 181.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2U987@28211|Alphaproteobacteria,2KGYK@204458|Caulobacterales 204458|Caulobacterales S Uncharacterised protein family (UPF0093) - - - ko:K08973 - - - - ko00000 - - - UPF0093 TGS3_k127_4072542_1 1528106.JRJE01000032_gene2857 1.067e-211 664.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,2JPVN@204441|Rhodospirillales 204441|Rhodospirillales K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind TGS3_k127_4072542_9 493475.GARC_4885 8.466e-51 189.0 2ECN7@1|root,336K3@2|Bacteria,1NV01@1224|Proteobacteria,1SRBC@1236|Gammaproteobacteria,46BJK@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_4072542_4 1121123.AUAO01000006_gene1977 1.237e-71 256.0 2ECN7@1|root,336K3@2|Bacteria,1P25W@1224|Proteobacteria,2UWWZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_4072542_8 1121949.AQXT01000002_gene1506 3.89e-59 214.0 2ECN7@1|root,336K3@2|Bacteria,1P25W@1224|Proteobacteria,2UWWZ@28211|Alphaproteobacteria,4406B@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_4081611_0 1247963.JPHU01000004_gene452 4.782e-197 628.0 COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,2U0FQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Alkaline phosphatase - - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N TGS3_k127_4081611_1 1174684.EBMC1_07825 3.46e-151 484.0 COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,2TSBX@28211|Alphaproteobacteria,2K1AI@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism - - 3.5.4.2 ko:K21053 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase TGS3_k127_4084705_0 941449.dsx2_1078 1.251e-207 668.0 COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,1PDZZ@1224|Proteobacteria,42M63@68525|delta/epsilon subdivisions,2WJDW@28221|Deltaproteobacteria 2|Bacteria E PFAM oxidoreductase - - - - - - - - - - - - ADH_N,ADH_zinc_N,GFO_IDH_MocA TGS3_k127_4084705_1 941449.dsx2_1079 0.0001065 53.0 COG0438@1|root,COG0500@1|root,COG0438@2|Bacteria,COG2226@2|Bacteria,1MU9C@1224|Proteobacteria,42WCU@68525|delta/epsilon subdivisions,2X5FB@28221|Deltaproteobacteria,2MGD0@213115|Desulfovibrionales 68525|delta/epsilon subdivisions M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 TGS3_k127_4091890_0 1247963.JPHU01000001_gene1765 6.907e-153 522.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2TR3B@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_C TGS3_k127_4091890_1 1247963.JPHU01000001_gene1764 2.99e-76 269.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2TR76@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Permease, YjgP YjgQ family lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ TGS3_k127_4103972_0 1247963.JPHU01000001_gene1922 4.542e-202 645.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TR3X@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains uup GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD TGS3_k127_4103972_1 1282360.ABAC460_04900 3.53e-142 467.0 COG0793@1|root,COG0793@2|Bacteria,1MW4H@1224|Proteobacteria,2TV4C@28211|Alphaproteobacteria,2KFRX@204458|Caulobacterales 204458|Caulobacterales M Peptidase family S41 - - - - - - - - - - - - Peptidase_S41 TGS3_k127_4103972_2 338969.Rfer_1231 1.366e-21 104.0 COG0457@1|root,COG0457@2|Bacteria,1N7YB@1224|Proteobacteria 1224|Proteobacteria F TIR domain - - - - - - - - - - - - TIR_2 TGS3_k127_4168063_1 314260.PB2503_10484 7.946e-07 59.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2UG3A@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme TGS3_k127_4168063_2 551789.ATVJ01000002_gene3020 7.672e-05 54.0 2AKR2@1|root,31BHW@2|Bacteria,1Q7CQ@1224|Proteobacteria,2V70Z@28211|Alphaproteobacteria,44011@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_4168063_0 1121948.AUAC01000002_gene1949 3.217e-63 223.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2TSDU@28211|Alphaproteobacteria,43XRG@69657|Hyphomonadaceae 28211|Alphaproteobacteria V MatE norM - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE TGS3_k127_4174430_2 1479238.JQMZ01000001_gene3 2.981e-104 349.0 COG3386@1|root,COG3386@2|Bacteria,1RFF0@1224|Proteobacteria,2U8ZK@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Arylesterase - - - - - - - - - - - - Arylesterase TGS3_k127_4174430_3 1382303.JPOM01000001_gene1526 6.574e-53 191.0 COG1514@1|root,COG1514@2|Bacteria,1RIHA@1224|Proteobacteria,2UAUZ@28211|Alphaproteobacteria,2KIQU@204458|Caulobacterales 204458|Caulobacterales J 2'-5' RNA ligase superfamily - - - - - - - - - - - - 2_5_RNA_ligase2 TGS3_k127_4174430_5 1247963.JPHU01000001_gene1847 2.662e-42 167.0 COG0667@1|root,COG0667@2|Bacteria,1PDY4@1224|Proteobacteria,2U9ZA@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red TGS3_k127_4174430_4 1280953.HOC_16436 2.091e-48 175.0 COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2U9QB@28211|Alphaproteobacteria,43XXV@69657|Hyphomonadaceae 28211|Alphaproteobacteria C Belongs to the glutaredoxin family. Monothiol subfamily grxC2 - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin TGS3_k127_4174430_0 1120956.JHZK01000004_gene1455 4.415e-233 731.0 COG1793@1|root,COG1793@2|Bacteria,1MV3S@1224|Proteobacteria,2TRQ9@28211|Alphaproteobacteria,1JNQU@119043|Rhodobiaceae 28211|Alphaproteobacteria L ATP dependent DNA ligase C terminal region lig - 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N TGS3_k127_4174430_1 1500301.JQMF01000002_gene714 3.24e-115 374.0 COG1236@1|root,COG1236@2|Bacteria,1MV7U@1224|Proteobacteria,2TQU5@28211|Alphaproteobacteria,4B91A@82115|Rhizobiaceae 28211|Alphaproteobacteria J exonuclease of the beta-lactamase fold involved in RNA processing MA20_22065 - - ko:K07577 - - - - ko00000 - - - Lactamase_B TGS3_k127_4178858_1 1089551.KE386572_gene1760 1.255e-142 463.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,2TUDG@28211|Alphaproteobacteria,4BRE1@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Aminotransferase class-III gabT - 2.6.1.19,2.6.1.22 ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 TGS3_k127_4178858_0 1123503.KB908059_gene249 9.325e-211 668.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,2KFRT@204458|Caulobacterales 204458|Caulobacterales EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N TGS3_k127_4178858_3 392499.Swit_2733 2.82e-91 310.0 COG5296@1|root,COG5296@2|Bacteria,1R36V@1224|Proteobacteria,2U7SA@28211|Alphaproteobacteria,2KEW7@204457|Sphingomonadales 204457|Sphingomonadales K RNA polymerase II C-terminal domain phosphoserine binding - - - - - - - - - - - - - TGS3_k127_4178858_4 1122613.ATUP01000001_gene534 1.278e-74 259.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,2TUQQ@28211|Alphaproteobacteria,43XBV@69657|Hyphomonadaceae 28211|Alphaproteobacteria N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella flaA GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N TGS3_k127_4178858_7 190650.CC_1459 1.905e-23 105.0 COG5442@1|root,COG5442@2|Bacteria,1N1GT@1224|Proteobacteria,2UCTU@28211|Alphaproteobacteria,2KGYA@204458|Caulobacterales 204458|Caulobacterales N PFAM flagellar FlaF family protein - - - ko:K06602 - - - - ko00000,ko02035 - - - FlaF TGS3_k127_4178858_6 573065.Astex_3111 7.956e-37 143.0 COG5443@1|root,COG5443@2|Bacteria,1RD3V@1224|Proteobacteria,2U7PK@28211|Alphaproteobacteria,2KGGZ@204458|Caulobacterales 204458|Caulobacterales N Has a post-transcriptional repressor function in flagellum biogenesis. Associates with the 5'-UTR of fljK flbT - - ko:K06601 - - - - ko00000,ko02035 - - - FlbT TGS3_k127_4178858_2 237727.NAP1_02765 2.196e-96 324.0 COG3000@1|root,COG3000@2|Bacteria,1NR7X@1224|Proteobacteria,2TT68@28211|Alphaproteobacteria,2K2GA@204457|Sphingomonadales 204457|Sphingomonadales I sterol desaturase - - - - - - - - - - - - FA_hydroxylase TGS3_k127_4178858_5 765869.BDW_01580 7.389e-72 248.0 COG3491@1|root,COG3491@2|Bacteria,1MUNT@1224|Proteobacteria,42QN8@68525|delta/epsilon subdivisions,2MSP0@213481|Bdellovibrionales,2WM0P@28221|Deltaproteobacteria 213481|Bdellovibrionales C Belongs to the iron ascorbate-dependent oxidoreductase family - - - - - - - - - - - - 2OG-FeII_Oxy,DIOX_N TGS3_k127_4205557_1 1123267.JONN01000001_gene1416 1.235e-115 382.0 COG0702@1|root,COG0702@2|Bacteria,1REY2@1224|Proteobacteria,2TS22@28211|Alphaproteobacteria,2K23H@204457|Sphingomonadales 204457|Sphingomonadales GM NAD(P)H-binding - - - - - - - - - - - - NAD_binding_10 TGS3_k127_4205557_4 1122612.AUBA01000011_gene862 4.253e-43 166.0 COG3011@1|root,COG3011@2|Bacteria,1Q3II@1224|Proteobacteria,2UFWG@28211|Alphaproteobacteria,2K6D2@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function, DUF393 - - - - - - - - - - - - DUF393 TGS3_k127_4205557_5 1117943.SFHH103_00280 2.84e-22 100.0 COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,2UDKN@28211|Alphaproteobacteria,4BHC9@82115|Rhizobiaceae 28211|Alphaproteobacteria S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc TGS3_k127_4205557_0 1120705.FG95_02069 6.218e-150 497.0 COG1228@1|root,COG1228@2|Bacteria,1MY4V@1224|Proteobacteria,2U3IV@28211|Alphaproteobacteria,2K1NC@204457|Sphingomonadales 204457|Sphingomonadales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 TGS3_k127_4205557_2 1449049.JONW01000010_gene3612 3.58e-70 246.0 COG2050@1|root,COG2050@2|Bacteria,1QVFN@1224|Proteobacteria,2TWDS@28211|Alphaproteobacteria,2KK70@204458|Caulobacterales 204458|Caulobacterales Q Thioesterase-like superfamily - - - - - - - - - - - - 4HBT_3 TGS3_k127_4205557_3 926569.ANT_29840 4.686e-48 177.0 COG0346@1|root,COG0346@2|Bacteria,2G7HN@200795|Chloroflexi 200795|Chloroflexi E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase TGS3_k127_4240820_3 1101192.KB910516_gene4121 4.824e-55 195.0 COG3293@1|root,COG3293@2|Bacteria,1RDDI@1224|Proteobacteria,2U7E3@28211|Alphaproteobacteria,1JZ12@119045|Methylobacteriaceae 28211|Alphaproteobacteria L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 TGS3_k127_4240820_4 69279.BG36_02100 1.197e-44 168.0 COG3293@1|root,COG3293@2|Bacteria,1MYPD@1224|Proteobacteria,2UBMY@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_2 TGS3_k127_4240820_5 1449049.JONW01000003_gene2049 1.254e-10 65.0 297C8@1|root,2ZUJT@2|Bacteria,1P6BP@1224|Proteobacteria,2UYNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_4240820_0 366602.Caul_3942 4.485e-219 706.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,2KFVS@204458|Caulobacterales 204458|Caulobacterales S Sulfotransferase - - - - - - - - - - - - Sulfotransfer_3,TPR_14,TPR_16,TPR_19,TPR_8 TGS3_k127_4240820_1 1207063.P24_11245 4.653e-174 559.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,2JPGU@204441|Rhodospirillales 204441|Rhodospirillales H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.96 ko:K16871 ko00250,ko00650,ko01100,ko01120,map00250,map00650,map01100,map01120 M00027 R10178 RC00008,RC00062 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_3 TGS3_k127_4240820_2 1247963.JPHU01000003_gene1284 8.806e-92 310.0 COG1216@1|root,COG1216@2|Bacteria,1R6SJ@1224|Proteobacteria,2U47V@28211|Alphaproteobacteria 28211|Alphaproteobacteria M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 TGS3_k127_4263002_4 1537715.JQFJ01000002_gene2531 1.572e-44 173.0 COG3826@1|root,COG3826@2|Bacteria,1MWVV@1224|Proteobacteria,2TQMH@28211|Alphaproteobacteria,2K2AB@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - ko:K09990 - - - - ko00000 - - - Oxygenase-NA TGS3_k127_4263002_7 883126.HMPREF9710_01360 1.428e-16 90.0 COG2169@1|root,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,2VIWW@28216|Betaproteobacteria,473RB@75682|Oxalobacteraceae 28216|Betaproteobacteria FL AlkA N-terminal domain ada - 3.2.2.21 ko:K13529 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD TGS3_k127_4263002_8 1207055.C100_19170 7.396e-15 86.0 COG3577@1|root,COG3577@2|Bacteria,1MYAD@1224|Proteobacteria,2U9RE@28211|Alphaproteobacteria,2K4GD@204457|Sphingomonadales 204457|Sphingomonadales S gag-polyprotein putative aspartyl protease - - - - - - - - - - - - Asp_protease_2,gag-asp_proteas TGS3_k127_4263002_3 1479238.JQMZ01000001_gene2449 3.654e-104 347.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2TRMT@28211|Alphaproteobacteria,43YJ2@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC TGS3_k127_4263002_5 1229204.AMYY01000056_gene1613 7.547e-37 143.0 COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,2TX9R@28211|Alphaproteobacteria 28211|Alphaproteobacteria M 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP TGS3_k127_4263002_1 1479238.JQMZ01000001_gene2450 2.78e-148 481.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2TQQS@28211|Alphaproteobacteria,43YAH@69657|Hyphomonadaceae 28211|Alphaproteobacteria E NAT, N-acetyltransferase, of N-acetylglutamate synthase - - 2.3.1.1,2.7.2.8 ko:K22478 ko00220,ko01210,ko01230,map00220,map01210,map01230 M00028,M00845 R00259,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,NAT TGS3_k127_4263002_6 1121948.AUAC01000003_gene2295 2.969e-29 122.0 COG2827@1|root,COG2827@2|Bacteria,1MZ4K@1224|Proteobacteria,2UHPS@28211|Alphaproteobacteria,43YN1@69657|Hyphomonadaceae 28211|Alphaproteobacteria L GIY-YIG catalytic domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG TGS3_k127_4263002_0 84531.JMTZ01000009_gene3281 1.787e-158 505.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1S7AW@1236|Gammaproteobacteria,1X35E@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the ATCase OTCase family argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 ko:K09065 ko00220,ko01100,ko01230,map00220,map01100,map01230 M00845 R07245 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N TGS3_k127_4263002_2 1123368.AUIS01000009_gene2455 1.502e-110 369.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,2NC0P@225057|Acidithiobacillales 225057|Acidithiobacillales E Domain of unknown function (DUF3458_C) ARM repeats pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 TGS3_k127_4265013_0 1122218.KB893654_gene2139 2.445e-86 295.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2U1EJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Type II secretory pathway, component ExeA exeA - - - - - - - - - - - AAA_22 TGS3_k127_4265013_3 314260.PB2503_10519 6.298e-54 200.0 COG0489@1|root,COG0489@2|Bacteria,1PDUC@1224|Proteobacteria,2U2MQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Involved in chromosome partitioning - - 2.7.10.1 ko:K08252 - - - - ko00000,ko01000 - - - AAA_31,CbiA,ParA TGS3_k127_4265013_1 314260.PB2503_10514 3.161e-86 305.0 COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2U1E2@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Chain-length determining protein - - - - - - - - - - - - GNVR,Wzz TGS3_k127_4265013_2 314260.PB2503_10509 2.124e-75 259.0 COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,2U835@28211|Alphaproteobacteria 28211|Alphaproteobacteria M polysaccharide export - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB TGS3_k127_4280572_1 1207063.P24_05927 1.16e-101 340.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2TRIM@28211|Alphaproteobacteria,2JQ24@204441|Rhodospirillales 204441|Rhodospirillales J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine - - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC TGS3_k127_4280572_0 1247963.JPHU01000005_gene264 3.212e-221 709.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria 28211|Alphaproteobacteria I acyl-CoA dehydrogenase mmgC - 1.3.8.1,1.3.8.7 ko:K00248,ko:K00249,ko:K20035 ko00071,ko00280,ko00410,ko00640,ko00650,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map00920,map01100,map01110,map01120,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754,R11130 RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246,RC03363 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N TGS3_k127_4280572_5 420324.KI912045_gene4530 1.521e-12 71.0 COG2002@1|root,COG2002@2|Bacteria,1QVJI@1224|Proteobacteria,2TWG9@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Addiction module antidote - - - - - - - - - - - - MazE_antitoxin TGS3_k127_4280572_3 1304872.JAGC01000003_gene3516 3.434e-37 145.0 COG3654@1|root,COG3654@2|Bacteria,1N1FW@1224|Proteobacteria,42V74@68525|delta/epsilon subdivisions,2WR7E@28221|Deltaproteobacteria,2ME13@213115|Desulfovibrionales 28221|Deltaproteobacteria S Fic/DOC family - - - ko:K07341 - - - - ko00000,ko02048 - - - Fic TGS3_k127_4280572_2 1247963.JPHU01000005_gene263 9.093e-66 235.0 COG1408@1|root,COG1408@2|Bacteria,1RK37@1224|Proteobacteria 1224|Proteobacteria S hydrolase activity yaeI - - ko:K07098 - - - - ko00000 - - - Metallophos,Metallophos_2 TGS3_k127_4280572_4 1550073.JROH01000011_gene2126 6.947e-31 125.0 COG3713@1|root,COG3713@2|Bacteria,1RERM@1224|Proteobacteria,2U7ER@28211|Alphaproteobacteria,2K36N@204457|Sphingomonadales 204457|Sphingomonadales M MltA-interacting protein MipA - - - - - - - - - - - - MipA TGS3_k127_4305276_1 1123059.KB823011_gene978 1.096e-38 159.0 COG1566@1|root,COG1566@2|Bacteria,1R50C@1224|Proteobacteria,2TUCN@28211|Alphaproteobacteria,440SZ@69657|Hyphomonadaceae 28211|Alphaproteobacteria V Protein of unknown function (DUF3667) - - - - - - - - - - - - DUF3667 TGS3_k127_4305276_0 551275.KB899544_gene1582 7.913e-63 228.0 COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,2U0P8@28211|Alphaproteobacteria,43XD3@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 TGS3_k127_4305276_2 551275.KB899544_gene1583 5.201e-26 116.0 COG1216@1|root,COG1216@2|Bacteria,1RAKR@1224|Proteobacteria,2U4HT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Glycosyltransferase family 87 - - - - - - - - - - - - GT87 TGS3_k127_4306717_5 1280954.HPO_10582 7.702e-62 218.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2TRDH@28211|Alphaproteobacteria,43WRN@69657|Hyphomonadaceae 28211|Alphaproteobacteria D Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system ttcA - - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 TGS3_k127_4306717_2 1121949.AQXT01000002_gene950 2.453e-106 360.0 COG1073@1|root,COG1073@2|Bacteria,1RK9G@1224|Proteobacteria,2UDV6@28211|Alphaproteobacteria,43XDB@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Acetyl xylan esterase domain-containing protein - - - - - - - - - - - - - TGS3_k127_4306717_6 1280952.HJA_08729 7.536e-59 212.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2TUU9@28211|Alphaproteobacteria,43XHF@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 TGS3_k127_4306717_8 985054.JQEZ01000002_gene3568 2.554e-37 148.0 2DHTP@1|root,300X5@2|Bacteria,1RDAJ@1224|Proteobacteria,2U7CF@28211|Alphaproteobacteria,4ND2N@97050|Ruegeria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_4306717_4 639283.Snov_0615 1.89e-92 313.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,3F213@335928|Xanthobacteraceae 28211|Alphaproteobacteria Q Dienelactone hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH TGS3_k127_4306717_11 1122613.ATUP01000001_gene1526 7.797e-20 92.0 COG3205@1|root,COG3205@2|Bacteria,1N85D@1224|Proteobacteria,2UK2K@28211|Alphaproteobacteria,43YGX@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Predicted membrane protein (DUF2061) - - - - - - - - - - - - DUF2061 TGS3_k127_4306717_3 1207063.P24_06741 2.652e-93 309.0 COG0349@1|root,COG0349@2|Bacteria,1MWFD@1224|Proteobacteria,2TQXS@28211|Alphaproteobacteria,2JQMC@204441|Rhodospirillales 204441|Rhodospirillales J 3'-5' exonuclease - - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1 TGS3_k127_4306717_10 314260.PB2503_06347 1.235e-22 108.0 COG5375@1|root,COG5375@2|Bacteria 2|Bacteria S Protein conserved in bacteria - - - ko:K11719 - - - - ko00000,ko02000 1.B.42.1 - - LptC TGS3_k127_4306717_9 314260.PB2503_06352 8.275e-27 115.0 COG1934@1|root,COG1934@2|Bacteria 2|Bacteria S lipopolysaccharide binding lptA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - iB21_1397.B21_03016,iECBD_1354.ECBD_0542,iECB_1328.ECB_03065,iECD_1391.ECD_03065 OstA TGS3_k127_4306717_1 1123355.JHYO01000012_gene765 2.454e-119 388.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2TR7F@28211|Alphaproteobacteria,36XK5@31993|Methylocystaceae 28211|Alphaproteobacteria S ATPases associated with a variety of cellular activities lptB - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C TGS3_k127_4306717_0 402881.Plav_0192 4.513e-167 548.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2TS41@28211|Alphaproteobacteria,1JNI2@119043|Rhodobiaceae 28211|Alphaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD TGS3_k127_4306717_7 314260.PB2503_06367 4.254e-39 151.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2TV3J@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE TGS3_k127_4349002_0 1122137.AQXF01000003_gene1995 1.764e-313 977.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the peptidase M16 family - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C TGS3_k127_4349002_2 394221.Mmar10_2615 1.026e-48 177.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,43WII@69657|Hyphomonadaceae 28211|Alphaproteobacteria S PFAM peptidase M16 domain protein - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C TGS3_k127_4349002_1 1211115.ALIQ01000154_gene4448 7.797e-60 216.0 COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,2TRH2@28211|Alphaproteobacteria,3NANE@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Prolyl 4-hydroxylase alpha subunit homologues. - - - ko:K07336 - - - - ko00000,ko01000 - - - 2OG-FeII_Oxy_3 TGS3_k127_4355776_2 1282876.BAOK01000001_gene2800 4.561e-52 198.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,2TUNX@28211|Alphaproteobacteria,4BQ18@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC - 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 TGS3_k127_4355776_0 1384054.N790_13085 7.577e-195 617.0 COG0031@1|root,COG0517@1|root,COG0031@2|Bacteria,COG0517@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1X4GC@135614|Xanthomonadales 135614|Xanthomonadales E Cystathionine beta-synthase cysB - 4.2.1.22 ko:K01697 ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230 M00035,M00338 R00891,R01290,R04942 RC00056,RC00069,RC00256,RC00489,RC01246 ko00000,ko00001,ko00002,ko01000 - - - CBS,PALP TGS3_k127_4355776_9 1384054.N790_06785 1.253e-19 94.0 2E2DB@1|root,32XI5@2|Bacteria,1N20T@1224|Proteobacteria,1T5Q3@1236|Gammaproteobacteria,1XBE9@135614|Xanthomonadales 135614|Xanthomonadales S Domain of unknown function (DUF4262) - - - - - - - - - - - - DUF4262 TGS3_k127_4355776_5 1333998.M2A_1991 2.568e-32 129.0 COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,2U98B@28211|Alphaproteobacteria,4BQYC@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P ArsC family MA20_27840 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC TGS3_k127_4355776_7 402881.Plav_1374 4.853e-30 121.0 COG3811@1|root,COG3811@2|Bacteria,1N7N0@1224|Proteobacteria,2UF95@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the UPF0386 family - - - ko:K09982 - - - - ko00000 - - - YjhX_toxin TGS3_k127_4355776_8 1090318.ATTI01000001_gene1233 2.323e-23 105.0 2CK6A@1|root,32ZDJ@2|Bacteria,1NEGT@1224|Proteobacteria,2UMXC@28211|Alphaproteobacteria,2K7MV@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - TGS3_k127_4355776_4 1247963.JPHU01000003_gene1462 1.35e-44 167.0 COG5321@1|root,COG5321@2|Bacteria,1RDXW@1224|Proteobacteria,2U73Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria S DNA repair protein MmcB-like MA20_23405 - - - - - - - - - - - MmcB-like TGS3_k127_4355776_3 394221.Mmar10_0081 8.543e-49 175.0 COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2U97J@28211|Alphaproteobacteria,43XZ5@69657|Hyphomonadaceae 28211|Alphaproteobacteria C Ferredoxin fdx - - ko:K04755 - - - - ko00000 - - - Fer2 TGS3_k127_4355776_1 1247963.JPHU01000008_gene2887 2.957e-126 416.0 COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Pyridine nucleotide-disulphide oxidoreductase - - 1.18.1.3 ko:K00529 ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220 M00545 R02000,R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002,ko01000 - - - Pyr_redox_2,Reductase_C TGS3_k127_4355776_6 1205680.CAKO01000042_gene5399 3.01e-32 138.0 COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2UBQ9@28211|Alphaproteobacteria,2JT79@204441|Rhodospirillales 204441|Rhodospirillales S Threonylcarbamoyl adenosine biosynthesis protein TsaE - - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE TGS3_k127_4361285_3 402881.Plav_2305 5.989e-148 475.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2TRBW@28211|Alphaproteobacteria,1JNC9@119043|Rhodobiaceae 28211|Alphaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 TGS3_k127_4361285_4 1123072.AUDH01000001_gene2806 5.269e-116 386.0 COG0415@1|root,COG0415@2|Bacteria,1MUKB@1224|Proteobacteria,2TR6A@28211|Alphaproteobacteria,2JV5J@204441|Rhodospirillales 204441|Rhodospirillales L FAD binding domain of DNA photolyase - - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - FAD_binding_7 TGS3_k127_4361285_1 228405.HNE_3082 1.248e-189 605.0 COG0415@1|root,COG0415@2|Bacteria,1MX6J@1224|Proteobacteria,2TTQX@28211|Alphaproteobacteria,43Z7N@69657|Hyphomonadaceae 28211|Alphaproteobacteria L Belongs to the DNA photolyase family - - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 TGS3_k127_4361285_6 652103.Rpdx1_0404 1.791e-47 179.0 COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,2TSEF@28211|Alphaproteobacteria,3JTEN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Uncharacterized protein family, UPF0114 yqhA - - - - - - - - - - - UPF0114 TGS3_k127_4361285_0 314254.OA2633_00655 1.079e-209 655.0 COG3508@1|root,COG3508@2|Bacteria,1MV9G@1224|Proteobacteria,2TRFI@28211|Alphaproteobacteria,43ZKK@69657|Hyphomonadaceae 28211|Alphaproteobacteria Q homogentisate 1,2-dioxygenase hmgA - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA TGS3_k127_4361285_9 670307.HYPDE_31473 2.55e-19 90.0 2EREK@1|root,33J04@2|Bacteria,1NKRV@1224|Proteobacteria,2UVAP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_4361285_7 1214101.BN159_0538 1.999e-44 165.0 COG2329@1|root,COG2329@2|Bacteria,2I6PF@201174|Actinobacteria 201174|Actinobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - - TGS3_k127_4361285_2 1231190.NA8A_17108 8.486e-161 512.0 COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,2TQYU@28211|Alphaproteobacteria,43HKP@69277|Phyllobacteriaceae 28211|Alphaproteobacteria Q 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase TGS3_k127_4361285_8 1370122.JHXQ01000008_gene1785 2.422e-34 141.0 COG4852@1|root,COG4852@2|Bacteria,1MZHP@1224|Proteobacteria,2UBSF@28211|Alphaproteobacteria,4BMWG@82115|Rhizobiaceae 28211|Alphaproteobacteria S Predicted membrane protein (DUF2177) - - - - - - - - - - - - DUF2177 TGS3_k127_4361285_5 1121127.JAFA01000001_gene852 7.517e-72 253.0 COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,2VVNG@28216|Betaproteobacteria,1K21M@119060|Burkholderiaceae 28216|Betaproteobacteria I Alpha beta hydrolase - - 3.1.1.83 ko:K14731 ko00903,ko00930,ko01220,map00903,map00930,map01220 - R03751,R06390,R06391,R06392,R06393 RC00713,RC00983,RC01505 ko00000,ko00001,ko01000 - - - Abhydrolase_3 TGS3_k127_4365724_2 1168059.KB899087_gene956 6.119e-45 167.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,3EY0N@335928|Xanthobacteraceae 28211|Alphaproteobacteria E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind TGS3_k127_4365724_1 670292.JH26_00600 1.642e-57 223.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2TRYU@28211|Alphaproteobacteria,1JRF1@119045|Methylobacteriaceae 28211|Alphaproteobacteria O PFAM PpiC-type peptidyl-prolyl cis-trans isomerase ppiD - 5.2.1.8 ko:K01802,ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2,SurA_N_3 TGS3_k127_4365724_0 1120792.JAFV01000001_gene975 2.992e-84 288.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2TS6I@28211|Alphaproteobacteria,36XTD@31993|Methylocystaceae 28211|Alphaproteobacteria G Triosephosphate isomerase tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM TGS3_k127_4365724_3 1038859.AXAU01000042_gene4952 1.354e-22 102.0 COG2267@1|root,COG2267@2|Bacteria,1MW9H@1224|Proteobacteria,2U1YC@28211|Alphaproteobacteria,3JUEG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 TGS3_k127_4368189_0 1161401.ASJA01000001_gene292 1.152e-190 614.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,43WFY@69657|Hyphomonadaceae 28211|Alphaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 TGS3_k127_4368189_1 1121124.JNIX01000007_gene345 6.97e-27 113.0 2ECZ8@1|root,336W9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - TGS3_k127_4395558_2 1333998.M2A_0290 1.4e-101 353.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria,4BPQS@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,GlnE,HD,NTP_transf_2 TGS3_k127_4395558_0 1247963.JPHU01000009_gene2349 7.026e-299 945.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2TQRR@28211|Alphaproteobacteria 28211|Alphaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V TGS3_k127_4395558_3 1333998.M2A_0355 8.851e-59 213.0 COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2U1JG@28211|Alphaproteobacteria,4BS5I@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function DUF45 MA20_23375 - - ko:K07043 - - - - ko00000 - - - DUF45 TGS3_k127_4395558_1 1207063.P24_14754 1.644e-158 520.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,2JQ4R@204441|Rhodospirillales 204441|Rhodospirillales M COG0744 Membrane carboxypeptidase (penicillin-binding protein) - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase TGS3_k127_4395558_4 1122137.AQXF01000003_gene2263 8.273e-26 115.0 COG1309@1|root,COG1309@2|Bacteria,1MZ9E@1224|Proteobacteria,2U0MU@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator - - - ko:K18301,ko:K19736 - M00642 - - ko00000,ko00002,ko01504,ko03000 - - - TetR_C_11,TetR_C_7,TetR_N TGS3_k127_44068_2 180281.CPCC7001_1601 3.491e-47 182.0 COG0457@1|root,COG0457@2|Bacteria,1GQEX@1117|Cyanobacteria 1117|Cyanobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - TGS3_k127_44068_0 1296415.JACC01000064_gene2542 1.018e-91 316.0 COG1228@1|root,COG1228@2|Bacteria 2|Bacteria Q imidazolonepropionase activity - - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Amidohydro_1 TGS3_k127_44068_3 1114959.SZMC14600_17839 2.483e-41 158.0 COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria,4EEP5@85010|Pseudonocardiales 201174|Actinobacteria L PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain ogt - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N TGS3_k127_44068_1 1333998.M2A_1236 1.978e-81 277.0 COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,2TRHN@28211|Alphaproteobacteria,4BPYB@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgH - - ko:K02393 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgH TGS3_k127_4432124_0 331869.BAL199_27081 4.14e-109 360.0 COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2TRCS@28211|Alphaproteobacteria,4BRUN@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Putative neutral zinc metallopeptidase - - - ko:K07054 - - - - ko00000 - - - Zn_peptidase TGS3_k127_4433537_8 1317124.DW2_11151 5.035e-09 63.0 2CM6A@1|root,32SDT@2|Bacteria,1N0P3@1224|Proteobacteria,2UCD1@28211|Alphaproteobacteria,2XNJA@285107|Thioclava 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_4433537_6 391593.RCCS2_08169 2.716e-14 81.0 COG1580@1|root,COG1580@2|Bacteria,1RH5D@1224|Proteobacteria,2U9BF@28211|Alphaproteobacteria,2P3A3@2433|Roseobacter 28211|Alphaproteobacteria N Controls the rotational direction of flagella during chemotaxis fliL - - ko:K02415 - - - - ko00000,ko02035 - - - FliL TGS3_k127_4433537_1 1530186.JQEY01000012_gene2547 1.417e-96 334.0 COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,2TR6J@28211|Alphaproteobacteria 28211|Alphaproteobacteria N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C TGS3_k127_4433537_7 759362.KVU_1950 3.15e-12 70.0 COG1886@1|root,COG1886@2|Bacteria,1MZKP@1224|Proteobacteria 1224|Proteobacteria N COG1886 Flagellar motor switch type III secretory pathway protein fliN - - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FliMN_C TGS3_k127_4433537_2 246200.SPO0196 2.431e-67 239.0 COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,2TT93@28211|Alphaproteobacteria,4NAFS@97050|Ruegeria 28211|Alphaproteobacteria N Plays a role in the flagellum-specific transport system fliP - - ko:K02419 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliP TGS3_k127_4433537_4 1280947.HY30_04670 1.443e-25 123.0 COG1536@1|root,COG1536@2|Bacteria,1PW25@1224|Proteobacteria,2V794@28211|Alphaproteobacteria,43ZDK@69657|Hyphomonadaceae 28211|Alphaproteobacteria N flagellar motor switch protein - - - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N TGS3_k127_4433537_0 388399.SSE37_17138 3.983e-130 424.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2TQNX@28211|Alphaproteobacteria 28211|Alphaproteobacteria N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgI - - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI TGS3_k127_4433537_5 391589.RGAI101_2724 4.516e-20 102.0 COG1344@1|root,COG1344@2|Bacteria,1MVTB@1224|Proteobacteria,2TVAK@28211|Alphaproteobacteria,2P2QH@2433|Roseobacter 28211|Alphaproteobacteria N Bacterial flagellin C-terminal helical region flgL - - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N TGS3_k127_4433537_3 1530186.JQEY01000005_gene3567 1.673e-31 129.0 COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,2TV1B@28211|Alphaproteobacteria 28211|Alphaproteobacteria N flagellar hook-associated protein flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C TGS3_k127_4438969_5 1545915.JROG01000001_gene359 6.735e-05 46.0 29JYC@1|root,306VM@2|Bacteria,1P5U0@1224|Proteobacteria,2UY2G@28211|Alphaproteobacteria,2KC3T@204457|Sphingomonadales 204457|Sphingomonadales S Antitoxin Phd_YefM, type II toxin-antitoxin system - - - - - - - - - - - - PhdYeFM_antitox TGS3_k127_4438969_1 570952.ATVH01000015_gene1547 1.773e-100 340.0 COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,2TUU2@28211|Alphaproteobacteria,2JRDH@204441|Rhodospirillales 204441|Rhodospirillales K acetyltransferase - - - - - - - - - - - - - TGS3_k127_4438969_3 1247963.JPHU01000006_gene109 3.997e-19 96.0 COG4704@1|root,COG4704@2|Bacteria,1NKU1@1224|Proteobacteria,2UN77@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2141) - - - - - - - - - - - - DUF2141 TGS3_k127_4438969_0 1161401.ASJA01000016_gene1354 3.992e-137 447.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQYP@28211|Alphaproteobacteria,43WUV@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Beta-eliminating lyase bioF - 2.3.1.29,2.3.1.47,2.3.1.50 ko:K00639,ko:K00652,ko:K00654 ko00260,ko00600,ko00780,ko01100,ko04071,ko04138,map00260,map00600,map00780,map01100,map04071,map04138 M00094,M00099,M00123,M00573,M00577 R00371,R01281,R03210,R10124 RC00004,RC00039,RC00394,RC02725,RC02849 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 TGS3_k127_4438969_2 1161401.ASJA01000016_gene1353 8.442e-22 98.0 COG0236@1|root,COG0236@2|Bacteria,1NHQD@1224|Proteobacteria,2UGSG@28211|Alphaproteobacteria,43YW5@69657|Hyphomonadaceae 28211|Alphaproteobacteria IQ acyl carrier protein - - - - - - - - - - - - PP-binding TGS3_k127_4438969_4 1174684.EBMC1_07245 3.478e-07 55.0 COG0702@1|root,COG0702@2|Bacteria,1RCCP@1224|Proteobacteria,2TU1D@28211|Alphaproteobacteria,2K0TF@204457|Sphingomonadales 204457|Sphingomonadales GM epimerase - - - - - - - - - - - - NAD_binding_10 TGS3_k127_446623_3 314285.KT71_06272 2.296e-67 240.0 COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,1RZDP@1236|Gammaproteobacteria,1J9C0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos TGS3_k127_446623_0 1545915.JROG01000001_gene137 4.109e-280 891.0 COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,2TRGM@28211|Alphaproteobacteria,2K25A@204457|Sphingomonadales 204457|Sphingomonadales F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C TGS3_k127_446623_1 397945.Aave_3002 1.091e-74 258.0 COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2VHHB@28216|Betaproteobacteria,4AAAY@80864|Comamonadaceae 28216|Betaproteobacteria KT PFAM response regulator receiver - - - ko:K07665 ko02020,map02020 M00452,M00745 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - Response_reg,Trans_reg_C TGS3_k127_446623_2 1123279.ATUS01000001_gene2466 8.538e-74 269.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNI8@1236|Gammaproteobacteria,1J6MA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K07642 ko02020,map02020 M00450,M00645,M00646,M00648 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA TGS3_k127_446623_4 927677.ALVU02000001_gene4662 2.106e-44 167.0 2DMEM@1|root,32R0F@2|Bacteria,1GHES@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - TGS3_k127_4484951_2 272943.RSP_0882 2.581e-106 355.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2TR5W@28211|Alphaproteobacteria,1FBA0@1060|Rhodobacter 28211|Alphaproteobacteria H Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS TGS3_k127_4484951_3 316056.RPC_2631 8.805e-59 210.0 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2U71I@28211|Alphaproteobacteria,3JSGD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene smpB - - ko:K03664 - - - - ko00000 - - - SmpB TGS3_k127_4484951_1 1279038.KB907339_gene1361 1.05e-110 366.0 COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,2TSNS@28211|Alphaproteobacteria,2JQ5T@204441|Rhodospirillales 204441|Rhodospirillales J Ribosomal protein L11 methyltransferase (PrmA) - - 2.1.1.298 ko:K07320 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03009 - - - MTS TGS3_k127_4484951_0 1247963.JPHU01000003_gene1193 4.313e-217 696.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2TRC1@28211|Alphaproteobacteria 28211|Alphaproteobacteria J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - RNB,S1 TGS3_k127_4488651_5 1121939.L861_14155 1.141e-45 172.0 COG2188@1|root,COG2188@2|Bacteria,1MUEB@1224|Proteobacteria,1RYZ9@1236|Gammaproteobacteria,1XPWX@135619|Oceanospirillales 135619|Oceanospirillales K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA TGS3_k127_4488651_6 1411123.JQNH01000001_gene2678 4.376e-44 162.0 COG2721@1|root,COG2721@2|Bacteria,1MZBN@1224|Proteobacteria,2UC3F@28211|Alphaproteobacteria 28211|Alphaproteobacteria G SAF - - 4.4.1.24 ko:K16845 ko00270,map00270 - R07633 RC01785 ko00000,ko00001,ko01000 - - - SAF TGS3_k127_4488651_0 1120983.KB894571_gene2251 4.156e-202 640.0 COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2TTDT@28211|Alphaproteobacteria,1JPQ2@119043|Rhodobiaceae 28211|Alphaproteobacteria G D-galactarate dehydratase / Altronate hydrolase, C terminus garD - 4.2.1.7,4.4.1.24 ko:K16846,ko:K16850 ko00040,ko00270,ko01100,map00040,map00270,map01100 M00631 R01540,R07633 RC00543,RC01785 ko00000,ko00001,ko00002,ko01000 - - - GD_AH_C TGS3_k127_4488651_2 414684.RC1_0266 5.692e-116 383.0 COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TR37@28211|Alphaproteobacteria,2JQ09@204441|Rhodospirillales 204441|Rhodospirillales C Belongs to the LDH2 MDH2 oxidoreductase family - - 1.1.1.338 ko:K16844 ko00270,ko01120,map00270,map01120 - R07137 RC00031 ko00000,ko00001,ko01000 - - - Ldh_2 TGS3_k127_4488651_4 472175.EL18_02199 2.246e-98 332.0 COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,2TVK9@28211|Alphaproteobacteria,43NBY@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 TGS3_k127_4488651_3 1231190.NA8A_14906 4.816e-113 379.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2U0AZ@28211|Alphaproteobacteria,43GWJ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA1 - 1.1.1.310 ko:K16843 ko00270,map00270 - R05693 RC00031 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C TGS3_k127_4488651_1 1089552.KI911559_gene3442 1.526e-181 583.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2TU11@28211|Alphaproteobacteria,2JQAF@204441|Rhodospirillales 204441|Rhodospirillales C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C TGS3_k127_4501777_4 886293.Sinac_6103 1.325e-26 114.0 COG1212@1|root,COG1212@2|Bacteria,2IYWF@203682|Planctomycetes 203682|Planctomycetes H Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 TGS3_k127_4501777_2 1123355.JHYO01000044_gene1215 1.254e-51 190.0 COG3806@1|root,COG3806@2|Bacteria,1RI6T@1224|Proteobacteria,2TVH9@28211|Alphaproteobacteria,36YVZ@31993|Methylocystaceae 28211|Alphaproteobacteria T ChrR Cupin-like domain chrR - - ko:K07167 - - - - ko00000 - - - Cupin_7,zf-HC2 TGS3_k127_4501777_1 1238182.C882_0398 1.698e-57 206.0 COG1595@1|root,COG1595@2|Bacteria,1RHRR@1224|Proteobacteria,2U9G0@28211|Alphaproteobacteria,2JS74@204441|Rhodospirillales 204441|Rhodospirillales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 TGS3_k127_4501777_0 438753.AZC_2436 4.675e-150 487.0 COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2TQUH@28211|Alphaproteobacteria,3F14F@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Flavin containing amine oxidoreductase - - - ko:K06954 - - - - ko00000 - - - Amino_oxidase TGS3_k127_4501777_3 1177928.TH2_07051 1.041e-49 182.0 COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2TUX0@28211|Alphaproteobacteria,2JRSA@204441|Rhodospirillales 204441|Rhodospirillales S Protein of unknown function (DUF1365) - - - ko:K09701 - - - - ko00000 - - - DUF1365 TGS3_k127_4564354_1 402777.KB235903_gene2620 9.565e-56 199.0 COG1741@1|root,COG1741@2|Bacteria,1G0UH@1117|Cyanobacteria,1H7AV@1150|Oscillatoriales 1117|Cyanobacteria S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin TGS3_k127_4564354_3 1123059.KB823012_gene2378 1.804e-26 126.0 COG0526@1|root,COG0526@2|Bacteria,1N81A@1224|Proteobacteria,2UGCI@28211|Alphaproteobacteria,43Y4I@69657|Hyphomonadaceae 28211|Alphaproteobacteria CO Thioredoxin-like - - - - - - - - - - - - Thioredoxin_7 TGS3_k127_4564354_0 228405.HNE_0914 1.949e-66 250.0 COG1680@1|root,COG1680@2|Bacteria,1NEV1@1224|Proteobacteria,2VF7G@28211|Alphaproteobacteria,43ZU9@69657|Hyphomonadaceae 28211|Alphaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase TGS3_k127_4564354_2 414684.RC1_3661 8.73e-38 145.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TTGJ@28211|Alphaproteobacteria,2JQ2F@204441|Rhodospirillales 204441|Rhodospirillales E Aspartate tyrosine aromatic aminotransferase - - - - - - - - - - - - Aminotran_1_2 TGS3_k127_4569627_3 395965.Msil_1622 3.231e-35 137.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2TR3W@28211|Alphaproteobacteria,3N9YN@45404|Beijerinckiaceae 28211|Alphaproteobacteria EF Carbamoyl-phosphate synthase small chain, CPSase domain carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase TGS3_k127_4569627_2 1247963.JPHU01000003_gene1195 2.202e-51 186.0 COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2U7DJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S GatB yqey MA20_04985 - - ko:K09117 - - - - ko00000 - - - YqeY TGS3_k127_4569627_1 1247963.JPHU01000001_gene1818 1.902e-154 509.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2TRU2@28211|Alphaproteobacteria 28211|Alphaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 TGS3_k127_4569627_0 1247963.JPHU01000001_gene1819 7.524e-250 784.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2TS6C@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 TGS3_k127_4613582_3 648757.Rvan_0236 2.207e-93 314.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2TS83@28211|Alphaproteobacteria,3N6KW@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh TGS3_k127_4613582_1 588932.JHOF01000005_gene2213 7.545e-127 416.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2TRKB@28211|Alphaproteobacteria,2KF6W@204458|Caulobacterales 204458|Caulobacterales E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB - 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA TGS3_k127_4613582_2 588932.JHOF01000027_gene1527 3.652e-122 414.0 COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1MUDC@1224|Proteobacteria,2TQWS@28211|Alphaproteobacteria,2KFVZ@204458|Caulobacterales 204458|Caulobacterales E homoserine dehydrogenase - - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Homoserine_dh,NAD_binding_3 TGS3_k127_4613582_0 1161401.ASJA01000022_gene114 2.593e-145 470.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria,43W9G@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Cys/Met metabolism PLP-dependent enzyme metB - 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP TGS3_k127_4613582_4 1121022.ABENE_13405 2.8e-82 284.0 COG2021@1|root,COG2021@2|Bacteria,1PNUE@1224|Proteobacteria,2V1DE@28211|Alphaproteobacteria,2KGUU@204458|Caulobacterales 204458|Caulobacterales E Belongs to the AB hydrolase superfamily. MetX family - - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 TGS3_k127_4613582_5 1380367.JIBC01000005_gene3407 1.724e-81 275.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,3ZWBM@60136|Sulfitobacter 28211|Alphaproteobacteria E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 TGS3_k127_462440_2 1121022.ABENE_09245 1.23e-25 111.0 COG2050@1|root,COG2050@2|Bacteria,1N088@1224|Proteobacteria,2UEDK@28211|Alphaproteobacteria,2KH05@204458|Caulobacterales 204458|Caulobacterales Q thioesterase - - - - - - - - - - - - 4HBT TGS3_k127_462440_1 314285.KT71_11585 2.837e-88 304.0 COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,1RMAC@1236|Gammaproteobacteria,1J5Q0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S EamA-like transporter family - - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA TGS3_k127_462440_0 648757.Rvan_3485 1.186e-179 572.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria,3N64Q@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC TGS3_k127_462440_3 383407.XOC_2097 8.969e-14 81.0 COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria,1X5HS@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - ko:K09973 - - - - ko00000 - - - TraB TGS3_k127_4643332_0 1247963.JPHU01000014_gene1005 1.211e-105 359.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TRCV@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the peptidase S11 family dacF - 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S11,SPOR TGS3_k127_4644968_1 402881.Plav_1922 3.237e-81 274.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2TSIP@28211|Alphaproteobacteria,1JN44@119043|Rhodobiaceae 28211|Alphaproteobacteria M Polysaccharide biosynthesis protein - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd TGS3_k127_4644968_0 1479238.JQMZ01000001_gene320 1.64e-214 673.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,43WJH@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family rkpK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N TGS3_k127_4644968_3 1207058.L53_01700 1.27e-40 164.0 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TWC3@28211|Alphaproteobacteria,43XUK@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 TGS3_k127_4669974_3 394221.Mmar10_2099 3.189e-36 142.0 COG4067@1|root,COG4067@2|Bacteria,1QXY3@1224|Proteobacteria,2TYFX@28211|Alphaproteobacteria,4415C@69657|Hyphomonadaceae 28211|Alphaproteobacteria O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease TGS3_k127_4669974_0 1123059.KB823011_gene1867 1.016e-144 463.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,2TRUH@28211|Alphaproteobacteria,43W5H@69657|Hyphomonadaceae 28211|Alphaproteobacteria HJO Belongs to the RimK family rimK - 6.3.2.32 ko:K05844,ko:K14940 ko00680,ko01120,map00680,map01120 - R09401 RC00064,RC00090 ko00000,ko00001,ko01000,ko03009 - - - RimK,Zn_protease TGS3_k127_4669974_4 1530186.JQEY01000008_gene3038 8.909e-22 106.0 COG0454@1|root,COG0456@2|Bacteria,1QWA8@1224|Proteobacteria,2TWUD@28211|Alphaproteobacteria 28211|Alphaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 TGS3_k127_4669974_2 1120705.FG95_01251 3.683e-64 228.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2TR41@28211|Alphaproteobacteria,2K6YP@204457|Sphingomonadales 204457|Sphingomonadales E Arginase family - - - - - - - - - - - - Arginase TGS3_k127_4669974_1 1122137.AQXF01000002_gene528 1.341e-99 328.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Phytoene dehydrogenase MA20_01895 - - - - - - - - - - - Amino_oxidase TGS3_k127_4673677_1 1333998.M2A_2112 1.902e-168 537.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR15@28211|Alphaproteobacteria,4BT83@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain MA20_22980 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N TGS3_k127_4673677_0 314260.PB2503_11134 1.129e-228 712.0 COG0538@1|root,COG0538@2|Bacteria,1MUIB@1224|Proteobacteria,2TQWD@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the isocitrate and isopropylmalate dehydrogenases family icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh TGS3_k127_469545_1 1247963.JPHU01000007_gene1573 1.521e-103 340.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2TRQH@28211|Alphaproteobacteria 28211|Alphaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 TGS3_k127_469545_0 1122970.AUHC01000009_gene232 3.929e-234 764.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TS4W@28211|Alphaproteobacteria,2KEEP@204457|Sphingomonadales 204457|Sphingomonadales P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec TGS3_k127_469545_2 190650.CC_3693 1.528e-23 104.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2UAPV@28211|Alphaproteobacteria,2KIM2@204458|Caulobacterales 204458|Caulobacterales Q MlaC protein - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC TGS3_k127_471281_5 693986.MOC_2319 0.0009594 44.0 2AAKN@1|root,30ZY5@2|Bacteria,1PMXV@1224|Proteobacteria,2V0IB@28211|Alphaproteobacteria,1JW0R@119045|Methylobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_471281_0 1121123.AUAO01000006_gene1946 2.842e-166 526.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2TRP3@28211|Alphaproteobacteria,2KFRW@204458|Caulobacterales 204458|Caulobacterales H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM TGS3_k127_471281_1 1121939.L861_05510 1.92e-48 181.0 COG0625@1|root,COG0625@2|Bacteria,1RD7K@1224|Proteobacteria,1S42S@1236|Gammaproteobacteria,1XPCN@135619|Oceanospirillales 135619|Oceanospirillales O Glutathione S-transferase, C-terminal domain - - - - - - - - - - - - GST_C_2,GST_N_3 TGS3_k127_471281_3 1417296.U879_12650 5.541e-40 154.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2U7D8@28211|Alphaproteobacteria 28211|Alphaproteobacteria I oligoketide cyclase lipid transport protein pasT - - ko:K18588 - - - - ko00000 - - - Polyketide_cyc TGS3_k127_471281_4 1449065.JMLL01000017_gene3974 1.07e-11 66.0 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2U94H@28211|Alphaproteobacteria,43K15@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Belongs to the CinA family cinA - 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA TGS3_k127_4722325_1 1545915.JROG01000007_gene3107 1.334e-173 547.0 COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2TRI7@28211|Alphaproteobacteria,2K23M@204457|Sphingomonadales 204457|Sphingomonadales S Circularly permuted ATP-grasp type 2 - - - - - - - - - - - - CP_ATPgrasp_2 TGS3_k127_4722325_3 1280947.HY30_10555 2.081e-116 382.0 COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,2TQUM@28211|Alphaproteobacteria,43WTR@69657|Hyphomonadaceae 28211|Alphaproteobacteria S protein conserved in bacteria MA20_32425 - - - - - - - - - - - Alpha-E TGS3_k127_4722325_6 1432050.IE4771_CH03423 1.618e-75 261.0 COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,2TTZY@28211|Alphaproteobacteria,4B991@82115|Rhizobiaceae 28211|Alphaproteobacteria E Transglutaminase-like MA20_32430 - - - - - - - - - - - Bact_transglu_N,Transglut_core TGS3_k127_4722325_4 1208323.B30_14614 3.287e-110 361.0 COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,2U09K@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Proteasome-type protease MA20_32445 - - ko:K07395 - - - - ko00000 - - - Proteasome TGS3_k127_4722325_0 1123503.KB908057_gene2503 1.229e-207 650.0 COG0451@1|root,COG0451@2|Bacteria,1MW8N@1224|Proteobacteria,2TSJB@28211|Alphaproteobacteria,2KFER@204458|Caulobacterales 204458|Caulobacterales GM GDP-mannose 4,6 dehydratase - - 3.13.1.1 ko:K06118 ko00520,ko00561,map00520,map00561 - R05775 RC01469 ko00000,ko00001,ko01000 - - - Epimerase TGS3_k127_4722325_2 1280949.HAD_08460 7.38e-139 447.0 COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2TQPI@28211|Alphaproteobacteria,43W5Z@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase TGS3_k127_4722325_5 1266998.ATUJ01000014_gene2343 1.893e-78 269.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2TSP6@28211|Alphaproteobacteria,2PUHF@265|Paracoccus 28211|Alphaproteobacteria M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind TGS3_k127_478501_1 1161401.ASJA01000001_gene295 7.693e-130 427.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2TUEW@28211|Alphaproteobacteria,43WI7@69657|Hyphomonadaceae 28211|Alphaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily tetA - - ko:K08151 - M00668 - - ko00000,ko00002,ko01504,ko02000 2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75 - - MFS_1,Sugar_tr TGS3_k127_478501_0 1247963.JPHU01000008_gene2802 1.749e-147 481.0 COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2TVZH@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Mg2 and Co2 transporter CorB corB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 TGS3_k127_478501_2 1282876.BAOK01000002_gene787 2.617e-126 421.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,4BPMA@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase,SKI TGS3_k127_478501_3 113395.AXAI01000007_gene1395 3.225e-37 144.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,3JU4S@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI TGS3_k127_4802263_11 1247963.JPHU01000004_gene528 1.914e-11 68.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains tacA GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - - - - - - - - - - HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat TGS3_k127_4802263_5 1161401.ASJA01000012_gene841 8.034e-72 254.0 COG0596@1|root,COG0596@2|Bacteria,1QYPD@1224|Proteobacteria,2UYZH@28211|Alphaproteobacteria,440PG@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_6 TGS3_k127_4802263_3 1097668.BYI23_B002170 8.903e-105 345.0 COG0426@1|root,COG0426@2|Bacteria,1MXIE@1224|Proteobacteria,2W9V7@28216|Betaproteobacteria,1K54Q@119060|Burkholderiaceae 28216|Betaproteobacteria C Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B TGS3_k127_4802263_1 1333998.M2A_2153 1.11e-137 448.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2TSZN@28211|Alphaproteobacteria,4BPHX@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C NAD(P) transhydrogenase, alpha subunit pntAA GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N TGS3_k127_4802263_7 314260.PB2503_10819 1.221e-41 162.0 COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,2UBXS@28211|Alphaproteobacteria 28211|Alphaproteobacteria C NADP transhydrogenase pntAB GO:0008150,GO:0008152,GO:0055114 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM TGS3_k127_4802263_0 1247963.JPHU01000004_gene525 8.375e-225 704.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2TQN1@28211|Alphaproteobacteria 28211|Alphaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB GO:0008150,GO:0008152,GO:0055114 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB TGS3_k127_4802263_4 1121948.AUAC01000006_gene579 1.453e-94 321.0 COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,2U5HN@28211|Alphaproteobacteria,43XFZ@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Methyltransferase - - - - - - - - - - - - - TGS3_k127_4802263_2 1380350.JIAP01000001_gene1727 1.513e-108 368.0 COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,2TSNH@28211|Alphaproteobacteria,43JCN@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K RNA polymerase sigma factor containing a TPR repeat domain - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 TGS3_k127_4802263_9 1122613.ATUP01000001_gene1282 2.262e-29 120.0 COG3795@1|root,COG3795@2|Bacteria,1N4SY@1224|Proteobacteria,2UBTF@28211|Alphaproteobacteria,4409Q@69657|Hyphomonadaceae 28211|Alphaproteobacteria S YCII-related domain - - - - - - - - - - - - YCII TGS3_k127_4802263_10 118166.JH976537_gene3317 1.886e-28 119.0 COG3795@1|root,COG3795@2|Bacteria,1G6M3@1117|Cyanobacteria,1HFTK@1150|Oscillatoriales 1117|Cyanobacteria S YCII-related domain - - - - - - - - - - - - YCII TGS3_k127_4802263_6 1337093.MBE-LCI_0205 1.623e-49 184.0 COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,2TRH2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S pkhd-type hydroxylase - - - ko:K07336 - - - - ko00000,ko01000 - - - 2OG-FeII_Oxy_3 TGS3_k127_4802263_8 1280950.HJO_06260 3.985e-39 153.0 2DV5K@1|root,33U5R@2|Bacteria,1MYQC@1224|Proteobacteria,2UB5F@28211|Alphaproteobacteria,43XQF@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_4808165_1 1247963.JPHU01000003_gene1409 5.028e-72 246.0 COG4805@1|root,COG4805@2|Bacteria,1PIM6@1224|Proteobacteria,2UAH8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 TGS3_k127_4808165_2 1174684.EBMC1_04239 7.097e-55 199.0 COG0671@1|root,COG0671@2|Bacteria,1RGM4@1224|Proteobacteria,2UIYA@28211|Alphaproteobacteria,2K5MY@204457|Sphingomonadales 204457|Sphingomonadales I Acid phosphatase homologues - - - - - - - - - - - - PAP2 TGS3_k127_4808165_0 1247963.JPHU01000002_gene2504 0.0 1782.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E glutamate synthase gltB - 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase TGS3_k127_4821858_1 1545915.JROG01000003_gene1242 1.659e-110 360.0 COG1629@1|root,COG4771@2|Bacteria,1QWIP@1224|Proteobacteria,2U11H@28211|Alphaproteobacteria,2K2RQ@204457|Sphingomonadales 204457|Sphingomonadales P Outer membrane protein beta-barrel family - - - - - - - - - - - - OMP_b-brl_3,Plug,TonB_dep_Rec TGS3_k127_4821858_0 314260.PB2503_02562 1.011e-166 533.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2TRPG@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA TGS3_k127_4836905_1 243159.AFE_0499 0.0009762 49.0 COG1403@1|root,COG1403@2|Bacteria,1P6JP@1224|Proteobacteria 1224|Proteobacteria V HNH endonuclease - - - - - - - - - - - - - TGS3_k127_4836905_0 1173026.Glo7428_2346 5.11e-55 205.0 COG4424@1|root,COG4424@2|Bacteria,1GQFR@1117|Cyanobacteria 1117|Cyanobacteria S PFAM sulfotransferase - - - - - - - - - - - - Sulfotransfer_1,Sulfotransfer_3 TGS3_k127_484073_2 1247963.JPHU01000001_gene2163 4.921e-105 354.0 COG4111@1|root,COG4111@2|Bacteria,1MXHA@1224|Proteobacteria,2TQQU@28211|Alphaproteobacteria 28211|Alphaproteobacteria F belongs to the nudix hydrolase family MA20_42130 - - - - - - - - - - - - TGS3_k127_484073_1 1280952.HJA_05132 1.886e-130 429.0 COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TS80@28211|Alphaproteobacteria,43ZHV@69657|Hyphomonadaceae 28211|Alphaproteobacteria P Transporter associated domain tlyC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 TGS3_k127_484073_0 1120705.FG95_02803 1.788e-193 621.0 COG1629@1|root,COG4771@2|Bacteria,1QWIP@1224|Proteobacteria,2U11H@28211|Alphaproteobacteria,2K2RQ@204457|Sphingomonadales 204457|Sphingomonadales P Outer membrane protein beta-barrel family - - - - - - - - - - - - OMP_b-brl_3,Plug,TonB_dep_Rec TGS3_k127_4856842_4 314260.PB2503_05382 9.69e-77 263.0 COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2TUDS@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Pilus assembly protein cpaE - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31,CBP_BcsQ TGS3_k127_4856842_0 1247963.JPHU01000009_gene2364 2.054e-252 784.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2TRNT@28211|Alphaproteobacteria 28211|Alphaproteobacteria U pilus assembly protein ATPase CpaF cpaF - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE TGS3_k127_4856842_3 1247963.JPHU01000009_gene2363 6.022e-106 353.0 COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,2TRBI@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Pilus assembly protein tadB - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF TGS3_k127_4856842_2 314260.PB2503_05397 4.298e-107 356.0 COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,2TSFA@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU type II secretion system protein tadC - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF TGS3_k127_4856842_7 1415756.JQMY01000001_gene2331 1.421e-29 125.0 2C9BB@1|root,34BS9@2|Bacteria,1P102@1224|Proteobacteria,2UUXF@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tellurite resistance protein TerB - - - - - - - - - - - - TerB TGS3_k127_4856842_1 1247963.JPHU01000012_gene878 9.018e-142 469.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2U35U@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - - - - - - - - - - SLT TGS3_k127_4856842_5 1247963.JPHU01000001_gene2157 2.195e-72 253.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2TT4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria L uracil-DNA glycosylase udgA - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG TGS3_k127_4856842_8 1385517.N800_13810 6.563e-13 70.0 COG3714@1|root,COG3714@2|Bacteria,1QE44@1224|Proteobacteria,1TAFY@1236|Gammaproteobacteria,1X8EB@135614|Xanthomonadales 135614|Xanthomonadales S YhhN family - - - - - - - - - - - - YhhN TGS3_k127_4875679_1 631454.N177_2421 6.887e-65 237.0 COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,2VET4@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 TGS3_k127_4875679_0 631454.N177_2422 4.787e-172 556.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,1JN93@119043|Rhodobiaceae 28211|Alphaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran TGS3_k127_4890027_2 314254.OA2633_04376 6.577e-16 77.0 COG1652@1|root,COG1652@2|Bacteria,1MWMR@1224|Proteobacteria,2U7UH@28211|Alphaproteobacteria,43YGZ@69657|Hyphomonadaceae 28211|Alphaproteobacteria S protein containing LysM domain lysM - - - - - - - - - - - LysM TGS3_k127_4890027_0 1247963.JPHU01000001_gene2008 0.0 1170.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2TRBK@28211|Alphaproteobacteria 28211|Alphaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim TGS3_k127_4890027_1 1333998.M2A_0349 4.155e-116 384.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,2TQRD@28211|Alphaproteobacteria,4BQ36@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF - - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - AAA_21,AAA_23,SMC_N TGS3_k127_4979525_2 1247963.JPHU01000001_gene1747 3.718e-106 353.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2TRJK@28211|Alphaproteobacteria 28211|Alphaproteobacteria G beta-N-acetylhexosaminidase nagZ - 3.2.1.21,3.2.1.52 ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 M00628 R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 - GH3 - Glyco_hydro_3 TGS3_k127_4979525_4 314260.PB2503_07127 3.39e-73 256.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2TS1V@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA TGS3_k127_4979525_5 1161401.ASJA01000018_gene1192 3.219e-67 240.0 COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2TU64@28211|Alphaproteobacteria,43WFU@69657|Hyphomonadaceae 28211|Alphaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB TGS3_k127_4979525_8 1121948.AUAC01000002_gene1101 3.644e-17 83.0 COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,2V712@28211|Alphaproteobacteria,43YUM@69657|Hyphomonadaceae 28211|Alphaproteobacteria U mttA/Hcf106 family - - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 TGS3_k127_4979525_7 1247963.JPHU01000001_gene1743 1.453e-20 94.0 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2UF4Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB GO:0003674,GO:0005215 - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 TGS3_k127_4979525_3 1247963.JPHU01000001_gene1742 1.185e-78 271.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2TTIX@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC TGS3_k127_4979525_0 435908.IDSA_06285 1.067e-166 530.0 COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RMNY@1236|Gammaproteobacteria,2QFKI@267893|Idiomarinaceae 1236|Gammaproteobacteria C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate tdh GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008652,GO:0008743,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046870,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_3926,iECUMN_1333.ECUMN_4133,iPC815.YPO0060 ADH_N,ADH_zinc_N TGS3_k127_4979525_1 351016.RAZWK3B_16130 3.913e-138 447.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2TS3F@28211|Alphaproteobacteria,2P2AE@2433|Roseobacter 28211|Alphaproteobacteria H Belongs to the ALAD family hemB GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD TGS3_k127_4979525_6 1247963.JPHU01000002_gene2523 1.145e-65 229.0 COG1846@1|root,COG1846@2|Bacteria,1RA1V@1224|Proteobacteria,2U5W6@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator mucS - - - - - - - - - - - HTH_27 TGS3_k127_4979525_9 317655.Sala_1547 2.741e-13 71.0 COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2TR4R@28211|Alphaproteobacteria,2K1JI@204457|Sphingomonadales 204457|Sphingomonadales C COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C TGS3_k127_5012068_1 1282876.BAOK01000001_gene1946 3.713e-05 54.0 COG0790@1|root,COG0790@2|Bacteria,1PAYM@1224|Proteobacteria,2UWKF@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0790 FOG TPR repeat, SEL1 subfamily - - - - - - - - - - - - - TGS3_k127_5012068_0 1129374.AJE_01514 9.812e-81 277.0 COG2819@1|root,COG2819@2|Bacteria,1QNQ2@1224|Proteobacteria,1TANG@1236|Gammaproteobacteria,46A9U@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative esterase - - - - - - - - - - - - Esterase TGS3_k127_5013496_0 266779.Meso_1325 5.622e-225 719.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2TQPT@28211|Alphaproteobacteria,43ITV@69277|Phyllobacteriaceae 28211|Alphaproteobacteria CE Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg TGS3_k127_502964_1 1197477.IA57_10560 5.247e-33 130.0 COG2827@1|root,COG2827@2|Bacteria,4NUYX@976|Bacteroidetes,1I4M9@117743|Flavobacteriia 976|Bacteroidetes L GIY-YIG catalytic domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG TGS3_k127_502964_0 1247963.JPHU01000003_gene1508 0.0 1070.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN TGS3_k127_5041283_4 1247963.JPHU01000018_gene3055 3.412e-46 177.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TSTS@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type Fe3 transport system, permease component sfuB - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 TGS3_k127_5041283_1 1247963.JPHU01000001_gene2033 2.395e-128 422.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 TGS3_k127_5041283_3 394221.Mmar10_0981 6.94e-63 228.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,2U17I@28211|Alphaproteobacteria,43XEY@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA TGS3_k127_5041283_0 1333998.M2A_2349 2.168e-212 668.0 COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,2TR0E@28211|Alphaproteobacteria,4BPG9@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E phospho-2-dehydro-3-deoxyheptonate aldolase aroF GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_2 TGS3_k127_5041283_2 1042377.AFPJ01000051_gene33 5.582e-90 305.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases - - - - - - - - - - - - Lactamase_B TGS3_k127_5041283_5 342610.Patl_0916 8.776e-22 103.0 COG3861@1|root,COG3861@2|Bacteria,1QVGH@1224|Proteobacteria,1RP36@1236|Gammaproteobacteria 1236|Gammaproteobacteria S electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - - - - - - - - - - - TGS3_k127_5042765_5 314260.PB2503_12954 1.914e-14 76.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria 28211|Alphaproteobacteria P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - ko:K03455,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.2 - - Na_H_Exchanger,TrkA_N TGS3_k127_5042765_0 1123054.KB907717_gene189 3.086e-203 646.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,1WXV7@135613|Chromatiales 135613|Chromatiales C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA - - - - - - - - - - - - Malate_synthase TGS3_k127_5042765_2 631454.N177_2151 1.381e-19 96.0 COG4961@1|root,COG4961@2|Bacteria,1N3XK@1224|Proteobacteria,2UBRJ@28211|Alphaproteobacteria,1JPGG@119043|Rhodobiaceae 28211|Alphaproteobacteria U TadE-like protein - - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - TadE TGS3_k127_5042765_3 1282361.ABAC402_12125 1.282e-17 90.0 COG4961@1|root,COG4961@2|Bacteria,1N744@1224|Proteobacteria,2UGR2@28211|Alphaproteobacteria,2KH1H@204458|Caulobacterales 204458|Caulobacterales U TadE-like protein - - - - - - - - - - - - TadE TGS3_k127_5042765_1 314260.PB2503_05577 3.917e-26 117.0 2DGNN@1|root,2ZWQ1@2|Bacteria,1NH3P@1224|Proteobacteria,2UM7I@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative bacterial sensory transduction regulator - - - - - - - - - - - - YbjN TGS3_k127_5042765_4 314260.PB2503_05572 8.348e-15 85.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,2TSIA@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family rsmB - 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,NusB TGS3_k127_5049142_1 1247963.JPHU01000007_gene1648 6.044e-179 565.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2TRIJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Phosphoglucomutase phosphomannomutase alpha beta alpha domain I algC - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV TGS3_k127_5049142_2 1247963.JPHU01000001_gene2070 4.414e-132 437.0 COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,2TU8A@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Nucleoside transporter MA20_32460 - - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N TGS3_k127_5049142_5 395965.Msil_1989 3.678e-47 179.0 28PSF@1|root,2ZCDZ@2|Bacteria,1RIKG@1224|Proteobacteria,2UEUQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of Unknown Function (DUF1543) - - - - - - - - - - - - DUF1543 TGS3_k127_5049142_4 1122603.ATVI01000006_gene804 4.429e-49 184.0 COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,1S4HQ@1236|Gammaproteobacteria,1X72V@135614|Xanthomonadales 135614|Xanthomonadales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA TGS3_k127_5049142_6 1173027.Mic7113_5753 1.807e-40 160.0 COG4122@1|root,COG4122@2|Bacteria,1G8BJ@1117|Cyanobacteria 1117|Cyanobacteria S O-methyltransferase activity - - - - - - - - - - - - Methyltransf_24 TGS3_k127_5049142_3 1502851.FG93_05437 4.014e-80 274.0 COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,2TSWU@28211|Alphaproteobacteria,3K33M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L UreE urease accessory protein, C-terminal domain - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG TGS3_k127_5049142_7 765698.Mesci_4812 9.05e-31 128.0 COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,2TTA3@28211|Alphaproteobacteria,43IU7@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K Peptidase_C39 like family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,DUF3335 TGS3_k127_5049142_0 551789.ATVJ01000003_gene255 1.167e-202 642.0 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,2TT53@28211|Alphaproteobacteria,43WAI@69657|Hyphomonadaceae 28211|Alphaproteobacteria HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - RLAN,RimK TGS3_k127_5098695_0 685778.AORL01000010_gene2631 9.135e-159 512.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,2K0U4@204457|Sphingomonadales 204457|Sphingomonadales L DEAD DEAH box helicase - - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C TGS3_k127_5098695_4 1002340.AFCF01000028_gene3139 5.28e-56 200.0 COG0590@1|root,COG0590@2|Bacteria,1RE8P@1224|Proteobacteria,2U9DE@28211|Alphaproteobacteria 28211|Alphaproteobacteria FJ MafB19-like deaminase MA20_41730 - 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 TGS3_k127_5098695_3 331869.BAL199_28225 1.024e-88 300.0 COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,2TRS7@28211|Alphaproteobacteria,4BPWD@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - - UPRTase TGS3_k127_5098695_1 1247963.JPHU01000009_gene2311 4.127e-140 451.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2TR6V@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA TGS3_k127_5098695_2 450851.PHZ_c0746 1.853e-90 312.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2TRAA@28211|Alphaproteobacteria,2KFAZ@204458|Caulobacterales 204458|Caulobacterales D Belongs to the 'phage' integrase family. XerC subfamily xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase TGS3_k127_5098695_6 573065.Astex_3452 7.826e-13 70.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,2KGME@204458|Caulobacterales 204458|Caulobacterales F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK - 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI TGS3_k127_5113878_1 1247963.JPHU01000001_gene1749 7.708e-170 542.0 COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2TRCD@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Belongs to the dGTPase family. Type 2 subfamily dgt GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc TGS3_k127_5113878_8 314260.PB2503_05577 1.643e-18 95.0 2DGNN@1|root,2ZWQ1@2|Bacteria,1NH3P@1224|Proteobacteria,2UM7I@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative bacterial sensory transduction regulator - - - - - - - - - - - - YbjN TGS3_k127_5113878_5 991905.SL003B_2348 8.586e-43 165.0 COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2UBR8@28211|Alphaproteobacteria,4BQX8@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the HesB IscA family erpA - - ko:K13628,ko:K15724 - - - - ko00000,ko03016 - - - Fe-S_biosyn TGS3_k127_5113878_6 717785.HYPMC_1652 1.071e-29 135.0 COG0740@1|root,COG0740@2|Bacteria 2|Bacteria OU serine-type endopeptidase activity clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease TGS3_k127_5113878_3 1122613.ATUP01000001_gene392 1.323e-86 293.0 COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,2U59W@28211|Alphaproteobacteria,4410M@69657|Hyphomonadaceae 28211|Alphaproteobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase TGS3_k127_5113878_7 1172188.KB911829_gene4423 4.71e-20 95.0 2FAVW@1|root,34330@2|Bacteria,2II2J@201174|Actinobacteria,4FJ96@85021|Intrasporangiaceae 201174|Actinobacteria S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 TGS3_k127_5113878_2 314254.OA2633_04301 3.535e-103 343.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2TR5J@28211|Alphaproteobacteria,43X4C@69657|Hyphomonadaceae 28211|Alphaproteobacteria L exodeoxyribonuclease III xth - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos TGS3_k127_5113878_9 402881.Plav_1691 2.597e-16 89.0 COG1525@1|root,COG1525@2|Bacteria,1R3VA@1224|Proteobacteria,2U0NK@28211|Alphaproteobacteria,1JPDG@119043|Rhodobiaceae 28211|Alphaproteobacteria L Staphylococcal nuclease homologue - - - - - - - - - - - - SNase TGS3_k127_5113878_0 190650.CC_3570 7.823e-185 599.0 COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,2TR2R@28211|Alphaproteobacteria,2KFNN@204458|Caulobacterales 204458|Caulobacterales M Penicillin-binding Protein - - 2.4.1.129 ko:K05367 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BiPBP_C,Transgly,Transpeptidase TGS3_k127_5113878_4 1207058.L53_00330 2.276e-44 165.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2TSAE@28211|Alphaproteobacteria,43WFC@69657|Hyphomonadaceae 28211|Alphaproteobacteria S COG2373 Large extracellular alpha-helical protein MA20_30110 - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,MG1,PAN_1,Thiol-ester_cl TGS3_k127_5144981_2 1282360.ABAC460_21045 9.517e-73 258.0 COG3660@1|root,COG3660@2|Bacteria,1R70U@1224|Proteobacteria,2TQWV@28211|Alphaproteobacteria,2KF7S@204458|Caulobacterales 204458|Caulobacterales M Mitochondrial fission ELM1 - - - ko:K07276 - - - - ko00000 - - - Mito_fiss_Elm1 TGS3_k127_5144981_3 585425.KR52_02975 4.868e-48 178.0 COG0783@1|root,COG0783@2|Bacteria,1G586@1117|Cyanobacteria,1H0B1@1129|Synechococcus 1117|Cyanobacteria P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin TGS3_k127_5144981_0 1333998.M2A_2360 3.38e-173 552.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TRPK@28211|Alphaproteobacteria,4BPDV@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E PFAM Aminotransferase class I and II aatA - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 TGS3_k127_5144981_1 342113.DM82_3223 6.648e-136 441.0 COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,2VJJQ@28216|Betaproteobacteria,1K237@119060|Burkholderiaceae 28216|Betaproteobacteria C PFAM L-carnitine dehydratase bile acid-inducible protein F - - 5.1.99.4 ko:K01796 ko00120,ko01100,ko04146,map00120,map01100,map04146 M00104 R08734,R08739 RC02345 ko00000,ko00001,ko00002,ko01000 - - - CoA_transf_3 TGS3_k127_5144997_1 685778.AORL01000022_gene1388 1.618e-59 222.0 COG1680@1|root,COG1680@2|Bacteria,1R60I@1224|Proteobacteria,2TV80@28211|Alphaproteobacteria,2K08P@204457|Sphingomonadales 204457|Sphingomonadales V Beta-lactamase - - - - - - - - - - - - Beta-lactamase TGS3_k127_5144997_0 1470591.BW41_02551 8.612e-72 251.0 COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2TRWY@28211|Alphaproteobacteria,2K1F9@204457|Sphingomonadales 204457|Sphingomonadales H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 moeB - 2.7.7.80 ko:K21029 ko04122,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF TGS3_k127_5144997_2 402881.Plav_3655 1.75e-58 207.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,1JP5I@119043|Rhodobiaceae 28211|Alphaproteobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase TGS3_k127_5146167_2 1267005.KB911256_gene1882 3.492e-134 439.0 COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,2TUN9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function DUF87 MA20_26515 - - ko:K06915 - - - - ko00000 - - - DUF87 TGS3_k127_5146167_3 378806.STAUR_1777 1.369e-100 338.0 COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,42NRH@68525|delta/epsilon subdivisions,2WNIB@28221|Deltaproteobacteria,2YV7G@29|Myxococcales 28221|Deltaproteobacteria E Asparaginase - - 3.4.19.5 ko:K13051 - - - - ko00000,ko01000,ko01002 - - - Asparaginase_2 TGS3_k127_5146167_4 1411123.JQNH01000001_gene2277 3.834e-65 239.0 COG4961@1|root,COG4961@2|Bacteria,1RA6J@1224|Proteobacteria,2U6PB@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad TGS3_k127_5146167_6 1123400.KB904748_gene320 7.626e-13 74.0 COG2002@1|root,COG2002@2|Bacteria,1N7NX@1224|Proteobacteria,1T0GU@1236|Gammaproteobacteria 1236|Gammaproteobacteria K SpoVT / AbrB like domain - - - - - - - - - - - - MazE_antitoxin TGS3_k127_5146167_5 1046724.KB889941_gene1203 3.794e-26 116.0 COG5611@1|root,COG5611@2|Bacteria,1N9JM@1224|Proteobacteria,1SEI3@1236|Gammaproteobacteria,46AZX@72275|Alteromonadaceae 1236|Gammaproteobacteria S PIN domain - - - - - - - - - - - - PIN TGS3_k127_5146167_1 883126.HMPREF9710_01028 7.961e-138 449.0 COG1680@1|root,COG1680@2|Bacteria,1R4P6@1224|Proteobacteria,2WC8Q@28216|Betaproteobacteria,4775G@75682|Oxalobacteraceae 28216|Betaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase TGS3_k127_5146167_0 1280952.HJA_09914 7.535e-152 488.0 COG1680@1|root,COG1680@2|Bacteria,1N6AK@1224|Proteobacteria,2UDQC@28211|Alphaproteobacteria 28211|Alphaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase TGS3_k127_5162753_4 1161401.ASJA01000014_gene1070 2.023e-32 126.0 COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,2U9D3@28211|Alphaproteobacteria,43XVT@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2237) - - - ko:K09966 - - - - ko00000 - - - DUF2237 TGS3_k127_5162753_3 1449065.JMLL01000010_gene258 1.588e-44 166.0 COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,2U9A2@28211|Alphaproteobacteria,43JY2@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S SufE protein probably involved in Fe-S center assembly sufE - - ko:K02426 - - - - ko00000 - - - SufE TGS3_k127_5162753_5 1267005.KB911258_gene354 4.897e-16 83.0 COG0593@1|root,COG0593@2|Bacteria,1N76V@1224|Proteobacteria,2UG3R@28211|Alphaproteobacteria,3N7FJ@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria L Bacterial dnaA protein helix-turn-helix domain - - - - - - - - - - - - Bac_DnaA_C TGS3_k127_5162753_0 46429.BV95_01524 1.238e-88 298.0 COG1192@1|root,COG1192@2|Bacteria,1MWH3@1224|Proteobacteria,2U100@28211|Alphaproteobacteria,2K0JR@204457|Sphingomonadales 204457|Sphingomonadales D involved in chromosome partitioning - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 TGS3_k127_5162753_1 1247963.JPHU01000005_gene354 1.348e-87 306.0 COG5330@1|root,COG5330@2|Bacteria,1QISN@1224|Proteobacteria,2TTV6@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Uncharacterised protein conserved in bacteria (DUF2336) - - - - - - - - - - - - DUF2336 TGS3_k127_5162753_6 1247963.JPHU01000005_gene355 1.48e-05 57.0 2EHM8@1|root,33BD0@2|Bacteria,1NMMG@1224|Proteobacteria,2UJZ0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_5162753_2 316055.RPE_0416 5.112e-48 177.0 COG1011@1|root,COG1011@2|Bacteria,1Q69X@1224|Proteobacteria,2TTTP@28211|Alphaproteobacteria,3JTMD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Haloacid dehalogenase-like hydrolase MA20_23095 - - ko:K07025 - - - - ko00000 - - - HAD_2 TGS3_k127_5186461_4 349163.Acry_2410 2.415e-21 96.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,2JP8N@204441|Rhodospirillales 204441|Rhodospirillales D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA TGS3_k127_5186461_5 1122613.ATUP01000001_gene349 3.082e-13 81.0 COG4319@1|root,COG4319@2|Bacteria,1MZRB@1224|Proteobacteria,2UK7M@28211|Alphaproteobacteria,440N5@69657|Hyphomonadaceae 28211|Alphaproteobacteria S SnoaL-like domain - - - - - - - - - - - - DUF4440,SnoaL_3 TGS3_k127_5186461_2 1247963.JPHU01000010_gene2256 2.395e-53 193.0 COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2U9GC@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 TGS3_k127_5186461_1 1463900.JOIX01000033_gene4280 2.239e-55 198.0 COG1247@1|root,COG1247@2|Bacteria,2IHSU@201174|Actinobacteria 201174|Actinobacteria M acetyltransferase - - - - - - - - - - - - Acetyltransf_1 TGS3_k127_5186461_0 1336245.JAGO01000011_gene321 3.39e-130 432.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,1XHH5@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt TGS3_k127_5186461_3 1415755.JQLV01000001_gene1529 9.324e-38 160.0 COG3449@1|root,COG3449@2|Bacteria,1QU1G@1224|Proteobacteria,1RSNB@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Domain of unknown function (DUF4153) yhgE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF4153 TGS3_k127_519604_3 1479238.JQMZ01000001_gene91 1.182e-36 151.0 COG2352@1|root,COG2352@2|Bacteria,1PUW3@1224|Proteobacteria,2V6E4@28211|Alphaproteobacteria,43WWC@69657|Hyphomonadaceae 28211|Alphaproteobacteria C Phosphoenolpyruvate carboxylase - - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase TGS3_k127_519604_0 414684.RC1_0267 2.73e-200 634.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2TRD7@28211|Alphaproteobacteria,2JR59@204441|Rhodospirillales 204441|Rhodospirillales F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N TGS3_k127_519604_1 1122137.AQXF01000005_gene1041 1.211e-195 626.0 COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,2TVJ1@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB glgE - 2.4.99.16 ko:K16147 ko00500,ko01100,map00500,map01100 - R09994 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3416,Malt_amylase_C TGS3_k127_519604_2 1123059.KB823011_gene1535 1.199e-52 199.0 COG1805@1|root,COG1805@2|Bacteria,1R88C@1224|Proteobacteria,2U32T@28211|Alphaproteobacteria,43Y11@69657|Hyphomonadaceae 28211|Alphaproteobacteria U Belongs to the NqrB RnfD family - - - - - - - - - - - - NQR2_RnfD_RnfE TGS3_k127_5219261_2 745310.G432_13920 1.207e-11 69.0 COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2TTU7@28211|Alphaproteobacteria,2K1IX@204457|Sphingomonadales 204457|Sphingomonadales S peptidase M48, Ste24p - - - - - - - - - - - - LysM,Peptidase_M48 TGS3_k127_5219261_1 1280946.HY29_13210 1.576e-96 326.0 COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,2TTEP@28211|Alphaproteobacteria,43XY0@69657|Hyphomonadaceae 28211|Alphaproteobacteria S 3-oxo-5-alpha-steroid 4-dehydrogenase - - - - - - - - - - - - DUF1295 TGS3_k127_5219261_0 1040986.ATYO01000014_gene698 5.145e-110 359.0 COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2TQQC@28211|Alphaproteobacteria,43H0V@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Belongs to the AlaDH PNT family ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N TGS3_k127_527989_0 314260.PB2503_09959 0.0 1049.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2TQV4@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD TGS3_k127_527989_3 1121015.N789_02320 3.45e-49 182.0 COG0346@1|root,COG0346@2|Bacteria,1N1D4@1224|Proteobacteria,1S7IY@1236|Gammaproteobacteria,1X7V3@135614|Xanthomonadales 135614|Xanthomonadales E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase TGS3_k127_527989_2 395492.Rleg2_1958 2.252e-174 552.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,4B8HC@82115|Rhizobiaceae 28211|Alphaproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA TGS3_k127_527989_5 113395.AXAI01000004_gene4547 6.732e-06 54.0 2BHHJ@1|root,32BJW@2|Bacteria,1REMD@1224|Proteobacteria,2U7XZ@28211|Alphaproteobacteria,3JYPI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S PilZ domain - - - - - - - - - - - - PilZ TGS3_k127_527989_1 1247963.JPHU01000001_gene1812 4.248e-294 921.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria 28211|Alphaproteobacteria I enoyl-CoA hydratase fadJ - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 TGS3_k127_527989_4 1122137.AQXF01000001_gene2941 2.607e-46 167.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TS1R@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N TGS3_k127_5281396_10 402881.Plav_2426 3.85e-53 199.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2TQZB@28211|Alphaproteobacteria,1JNKE@119043|Rhodobiaceae 28211|Alphaproteobacteria D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA TGS3_k127_5281396_11 402881.Plav_2425 1.668e-41 165.0 COG1589@1|root,COG1589@2|Bacteria,1MY1Q@1224|Proteobacteria,2TQPU@28211|Alphaproteobacteria,1JPB0@119043|Rhodobiaceae 28211|Alphaproteobacteria D POTRA domain, FtsQ-type ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 TGS3_k127_5281396_5 394221.Mmar10_2074 2.885e-130 422.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2TREC@28211|Alphaproteobacteria,43W7H@69657|Hyphomonadaceae 28211|Alphaproteobacteria F Belongs to the D-alanine--D-alanine ligase family ddl - 1.3.1.98,6.3.2.4 ko:K00075,ko:K01921 ko00473,ko00520,ko00550,ko01100,ko01502,map00473,map00520,map00550,map01100,map01502 - R01150,R03191,R03192 RC00064,RC00141,RC02639 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N TGS3_k127_5281396_7 1121948.AUAC01000002_gene1440 5.088e-110 363.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2TRQR@28211|Alphaproteobacteria,43W9B@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C TGS3_k127_5281396_0 1247963.JPHU01000003_gene1351 2.266e-203 653.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2TRT0@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M TGS3_k127_5281396_9 1247963.JPHU01000003_gene1352 8.112e-100 353.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2TSEY@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 TGS3_k127_5281396_8 1247963.JPHU01000003_gene1353 2.713e-106 357.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2TQSA@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE TGS3_k127_5281396_3 1449049.JONW01000003_gene2050 2.039e-146 477.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2TTE8@28211|Alphaproteobacteria,2KF97@204458|Caulobacterales 204458|Caulobacterales M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M TGS3_k127_5281396_4 269796.Rru_A0953 6.047e-146 471.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,2JQ3T@204441|Rhodospirillales 204441|Rhodospirillales M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 TGS3_k127_5281396_2 1247963.JPHU01000003_gene1356 1.922e-158 513.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2TR0Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10,6.3.2.13 ko:K01928,ko:K01929,ko:K15792 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M TGS3_k127_5281396_1 1247963.JPHU01000003_gene1357 2.684e-161 522.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2TVXI@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M TGS3_k127_5281396_6 314260.PB2503_09694 1.407e-126 428.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2TSHQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Cell division protein FtsI penicillin-binding protein 2 ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase TGS3_k127_5282075_0 670307.HYPDE_34808 0.0 1493.0 COG0642@1|root,COG1352@1|root,COG2201@1|root,COG4566@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,COG4566@2|Bacteria,1NRP8@1224|Proteobacteria,2TWP9@28211|Alphaproteobacteria 28211|Alphaproteobacteria T catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - 2.1.1.80,3.1.1.61 ko:K00575,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,CheR,CheR_N,GerE,HATPase_c,HisKA,PAS_10,Response_reg TGS3_k127_5282075_1 1247963.JPHU01000007_gene1686 4.589e-44 168.0 COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2TUUZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 TGS3_k127_5282075_2 1282360.ABAC460_22810 7.485e-27 111.0 COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,2UFM5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM Transglycosylase-associated protein MA20_19350 - - - - - - - - - - - Transgly_assoc TGS3_k127_5282075_3 1280954.HPO_02727 6.85e-18 94.0 COG1873@1|root,COG1873@2|Bacteria,1NADN@1224|Proteobacteria,2UHJI@28211|Alphaproteobacteria,44092@69657|Hyphomonadaceae 28211|Alphaproteobacteria S PRC-barrel domain - - - - - - - - - - - - PRC TGS3_k127_530528_1 1479238.JQMZ01000001_gene1408 7.945e-96 321.0 COG1024@1|root,COG1024@2|Bacteria,1NDT7@1224|Proteobacteria,2U2R9@28211|Alphaproteobacteria,43XFU@69657|Hyphomonadaceae 28211|Alphaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 TGS3_k127_530528_0 1282876.BAOK01000001_gene2298 4.873e-157 507.0 COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,4BP8K@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C NADH:flavin oxidoreductase / NADH oxidase family - - 1.5.8.1,1.5.8.2 ko:K00317 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R01588,R02511 RC00185,RC00556,RC00557,RC00732 ko00000,ko00001,ko01000 - - - Oxidored_FMN,Pyr_redox_2 TGS3_k127_530528_2 1192759.AKIB01000008_gene215 8.11e-60 211.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,2U997@28211|Alphaproteobacteria,2K4GS@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the UPF0178 family - - - ko:K09768 - - - - ko00000 - - - DUF188 TGS3_k127_5349754_5 450851.PHZ_c0427 5.348e-77 263.0 COG1215@1|root,COG1215@2|Bacteria,1QVG6@1224|Proteobacteria,2TWF3@28211|Alphaproteobacteria,2KFY3@204458|Caulobacterales 204458|Caulobacterales M Glycosyl transferase family 2 - - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 TGS3_k127_5349754_7 314260.PB2503_07734 3.722e-32 130.0 2E6XE@1|root,331GU@2|Bacteria,1N7WP@1224|Proteobacteria,2UG23@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_5349754_4 314260.PB2503_02192 2.48e-95 312.0 COG2329@1|root,COG2329@2|Bacteria,1RAC6@1224|Proteobacteria,2U59M@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF3291) - - - - - - - - - - - - DUF3291 TGS3_k127_5349754_1 1247963.JPHU01000011_gene821 2.504e-187 605.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2UP6H@28211|Alphaproteobacteria 28211|Alphaproteobacteria T GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS_3 TGS3_k127_5349754_0 1510531.JQJJ01000015_gene3016 0.0 1113.0 COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,2TSG9@28211|Alphaproteobacteria,3JRME@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Serves to protect cells from the toxic effects of hydrogen peroxide katE - 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel TGS3_k127_5349754_6 402881.Plav_1572 2.099e-61 218.0 COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,2TQWQ@28211|Alphaproteobacteria,1JNVK@119043|Rhodobiaceae 28211|Alphaproteobacteria S PHB accumulation regulatory domain phaR - - - - - - - - - - - PHB_acc,PHB_acc_N TGS3_k127_5349754_2 1335760.ASTG01000013_gene2514 7.262e-170 544.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2JZW1@204457|Sphingomonadales 204457|Sphingomonadales I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N TGS3_k127_5349754_3 1121479.AUBS01000002_gene3704 4.003e-104 345.0 COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2TRCF@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Acetoacetyl-CoA reductase phbB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.36 ko:K00023 ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200 M00373 R01779,R01977 RC00103,RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 TGS3_k127_5349754_8 1449049.JONW01000005_gene1517 1.071e-06 58.0 2ARAD@1|root,31GKB@2|Bacteria,1RJG7@1224|Proteobacteria,2UBC4@28211|Alphaproteobacteria,2KGQ5@204458|Caulobacterales 204458|Caulobacterales S Domain of unknown function (DUF4908) - - - - - - - - - - - - DUF4908 TGS3_k127_5354865_7 1510531.JQJJ01000011_gene2812 9.4e-10 62.0 COG0340@1|root,COG0340@2|Bacteria,1MWCC@1224|Proteobacteria,2TS82@28211|Alphaproteobacteria,3JR9E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Biotin protein ligase C terminal domain birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB TGS3_k127_5354865_2 69395.JQLZ01000005_gene3758 3.381e-106 351.0 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2TS5A@28211|Alphaproteobacteria,2KFJA@204458|Caulobacterales 204458|Caulobacterales F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase TGS3_k127_5354865_0 1247963.JPHU01000008_gene2794 1.942e-216 685.0 COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,2TQTR@28211|Alphaproteobacteria 28211|Alphaproteobacteria H hydrolase of the metallo-beta-lactamase superfamily rnjA - - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,Lactamase_B_2,RMMBL TGS3_k127_5354865_6 1161401.ASJA01000007_gene2071 8.029e-16 79.0 COG5454@1|root,COG5454@2|Bacteria,1NGEG@1224|Proteobacteria,2UJHR@28211|Alphaproteobacteria,43YUS@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1467) - - - - - - - - - - - - DUF1467 TGS3_k127_5354865_1 1247963.JPHU01000008_gene2796 2.675e-157 510.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N TGS3_k127_5354865_3 314260.PB2503_01067 5.312e-105 350.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U7RQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme TGS3_k127_5354865_4 1041147.AUFB01000011_gene1652 3.473e-48 176.0 COG5458@1|root,COG5458@2|Bacteria,1N054@1224|Proteobacteria,2UBY1@28211|Alphaproteobacteria,4BE3H@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1489) MA20_36070 - - - - - - - - - - - DUF1489 TGS3_k127_5367820_3 1247963.JPHU01000004_gene513 4.896e-113 376.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins nifS GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 TGS3_k127_5367820_0 1121948.AUAC01000002_gene1353 3.23e-250 781.0 COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,2TRU6@28211|Alphaproteobacteria,43WGU@69657|Hyphomonadaceae 28211|Alphaproteobacteria O COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component sufB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0009842,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - ko:K09014 - - - - ko00000 - - - UPF0051 TGS3_k127_5367820_10 1280952.HJA_07787 3.968e-15 79.0 COG0251@1|root,COG0251@2|Bacteria,1PHJK@1224|Proteobacteria,2V89Y@28211|Alphaproteobacteria,4405J@69657|Hyphomonadaceae 28211|Alphaproteobacteria J translation initiation inhibitor, yjgF family - - - - - - - - - - - - Ribonuc_L-PSP TGS3_k127_5367820_7 517722.AEUE01000001_gene2441 1.907e-34 143.0 2BXIR@1|root,31GT8@2|Bacteria,1N57Y@1224|Proteobacteria,2UT7B@28211|Alphaproteobacteria,2KAP6@204457|Sphingomonadales 204457|Sphingomonadales S Cupin domain - - - - - - - - - - - - Cupin_2 TGS3_k127_5367820_2 314260.PB2503_09904 2.852e-121 394.0 COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2TS8T@28211|Alphaproteobacteria 28211|Alphaproteobacteria O FeS assembly ATPase SufC sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran TGS3_k127_5367820_4 1161401.ASJA01000007_gene2030 3.955e-76 271.0 COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,2TTK9@28211|Alphaproteobacteria,43XC9@69657|Hyphomonadaceae 28211|Alphaproteobacteria O COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component sufD - - ko:K09015 - - - - ko00000 - - - UPF0051 TGS3_k127_5367820_1 1168059.KB899087_gene1601 8.047e-160 516.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TRNY@28211|Alphaproteobacteria,3EYDF@335928|Xanthobacteraceae 28211|Alphaproteobacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 TGS3_k127_5367820_6 394221.Mmar10_1320 1.346e-49 179.0 COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2U72U@28211|Alphaproteobacteria,43XUM@69657|Hyphomonadaceae 28211|Alphaproteobacteria S FeS assembly SUF system protein - - - - - - - - - - - - FeS_assembly_P TGS3_k127_5367820_5 314260.PB2503_09934 2.508e-55 195.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2UBWJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the HesB IscA family iscA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn TGS3_k127_5367820_8 1122132.AQYH01000010_gene4105 2.427e-25 110.0 COG3070@1|root,COG3070@2|Bacteria,1N8X8@1224|Proteobacteria,2UFNC@28211|Alphaproteobacteria,4BFM8@82115|Rhizobiaceae 28211|Alphaproteobacteria K regulator of competence-specific genes MA20_30690 - - ko:K07343 - - - - ko00000 - - - TfoX_N TGS3_k127_5367820_9 744980.TRICHSKD4_4354 3.04e-17 81.0 COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,2TT93@28211|Alphaproteobacteria 28211|Alphaproteobacteria N Plays a role in the flagellum-specific transport system fliP - - ko:K02419 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliP TGS3_k127_5367897_6 1280954.HPO_02162 9.619e-39 146.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSUQ@28211|Alphaproteobacteria,43WBM@69657|Hyphomonadaceae 28211|Alphaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF885 TGS3_k127_5367897_3 1280954.HPO_08154 3.761e-83 286.0 COG0596@1|root,COG0596@2|Bacteria,1Q47F@1224|Proteobacteria,2U3WB@28211|Alphaproteobacteria 28211|Alphaproteobacteria I hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 TGS3_k127_5367897_4 1247963.JPHU01000003_gene1499 4.151e-82 280.0 COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,2VFCW@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 TGS3_k127_5367897_7 394221.Mmar10_3000 6.109e-36 147.0 COG2520@1|root,COG2520@2|Bacteria,1QZWN@1224|Proteobacteria,2TYG6@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 TGS3_k127_5367897_1 1219076.N646_2734 1.231e-91 309.0 COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1XV5N@135623|Vibrionales 135623|Vibrionales S Polyphosphate kinase 2 (PPK2) - - 2.7.4.1 ko:K22468 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PPK2 TGS3_k127_5367897_0 1247963.JPHU01000002_gene2594 6.95e-101 349.0 COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2TTUR@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 TGS3_k127_5367897_2 1247963.JPHU01000002_gene2595 7.969e-88 302.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2TQSY@28211|Alphaproteobacteria 28211|Alphaproteobacteria V transport, permease protein yadH - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane TGS3_k127_5367897_5 314260.PB2503_05422 7.947e-44 167.0 COG5352@1|root,COG5352@2|Bacteria,1RHI6@1224|Proteobacteria,2TS7F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S GcrA cell cycle regulator gcrA - - ko:K13583 ko04112,map04112 - - - ko00000,ko00001 - - - GcrA TGS3_k127_5393425_1 1247963.JPHU01000005_gene412 1.058e-14 88.0 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - 4.2.2.1 ko:K01727 - - - - ko00000,ko01000 - PL8 - - TGS3_k127_5393425_0 1211115.ALIQ01000007_gene1067 2.026e-196 626.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TREJ@28211|Alphaproteobacteria,3NC7M@45404|Beijerinckiaceae 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain ivd2 - 1.3.8.4 ko:K00253 ko00280,ko01100,map00280,map01100 M00036 R04095 RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N TGS3_k127_5393425_2 936136.ARRT01000006_gene5582 1.918e-07 55.0 COG3668@1|root,COG3668@2|Bacteria,1N9GA@1224|Proteobacteria,2UFUV@28211|Alphaproteobacteria,4BGAA@82115|Rhizobiaceae 28211|Alphaproteobacteria S ParE toxin of type II toxin-antitoxin system, parDE - - - ko:K19092 - - - - ko00000,ko02048 - - - ParE_toxin TGS3_k127_5396035_1 1247963.JPHU01000003_gene1440 3.514e-128 432.0 COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - 2.7.13.3 ko:K20974 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,Response_reg,SBP_bac_3,dCache_1 TGS3_k127_5396035_0 1035191.HMPREF0185_02159 1.782e-133 445.0 COG2271@1|root,COG2271@2|Bacteria,1QUF4@1224|Proteobacteria,2TW2A@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG0477 Permeases of the major facilitator superfamily ampG2 - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - Acatn,MFS_1 TGS3_k127_5449041_1 1123240.ATVO01000003_gene187 1.609e-52 196.0 COG3504@1|root,COG3504@2|Bacteria,1MVHJ@1224|Proteobacteria,2U07J@28211|Alphaproteobacteria,2K5GF@204457|Sphingomonadales 204457|Sphingomonadales U Conjugal transfer protein - - - - - - - - - - - - CagX TGS3_k127_5449041_2 573065.Astex_1332 8.798e-36 151.0 COG3704@1|root,COG3704@2|Bacteria,1R9F8@1224|Proteobacteria,2U0XT@28211|Alphaproteobacteria,2KIBK@204458|Caulobacterales 204458|Caulobacterales U TrbL/VirB6 plasmid conjugal transfer protein - - - ko:K03201 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - TrbL TGS3_k127_5449041_0 1121022.ABENE_00995 2.982e-56 200.0 COG3451@1|root,COG3451@2|Bacteria,1MXH0@1224|Proteobacteria,2TR1U@28211|Alphaproteobacteria,2KEYI@204458|Caulobacterales 204458|Caulobacterales U Type VI secretion protein - - - ko:K03199 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - CagE_TrbE_VirB TGS3_k127_5449698_1 402881.Plav_0105 9.492e-108 352.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,1JN6G@119043|Rhodobiaceae 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 TGS3_k127_5449698_0 1122214.AQWH01000055_gene2670 8.047e-173 563.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2PIZV@255475|Aurantimonadaceae 28211|Alphaproteobacteria V AcrB/AcrD/AcrF family acrD - - ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran TGS3_k127_5450850_0 1247963.JPHU01000011_gene797 7.49e-115 382.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2TQTQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C TGS3_k127_5450850_1 1247963.JPHU01000011_gene727 2.535e-113 377.0 COG3409@1|root,COG5480@1|root,COG3409@2|Bacteria,COG5480@2|Bacteria,1P9ZA@1224|Proteobacteria,2TSTF@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Protein of unknown function (DUF1036) MA20_21840 - - - - - - - - - - - DUF1036,PG_binding_1 TGS3_k127_5450850_2 1247963.JPHU01000011_gene728 2.551e-84 287.0 COG1011@1|root,COG1011@2|Bacteria,1PHPQ@1224|Proteobacteria,2TUDN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Pyrimidine 5'-nucleotidase MA20_21845 - - ko:K07025 - - - - ko00000 - - - HAD_2 TGS3_k127_5462030_1 1187851.A33M_0653 1.078e-93 308.0 COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TRI8@28211|Alphaproteobacteria,3FCRV@34008|Rhodovulum 28211|Alphaproteobacteria O AAA domain (Cdc48 subfamily) MA20_01295 - - - - - - - - - - - AAA,AAA_5 TGS3_k127_5462030_3 1122134.KB893651_gene1915 9.921e-52 191.0 COG3182@1|root,COG3182@2|Bacteria,1R59B@1224|Proteobacteria,1S0MV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S conserved secreted or membrane protein precursor - - - - - - - - - - - - PepSY_TM TGS3_k127_5462030_0 1449049.JONW01000005_gene1295 1.179e-123 409.0 COG4805@1|root,COG4805@2|Bacteria,1MZDR@1224|Proteobacteria,2TTBI@28211|Alphaproteobacteria,2KHV4@204458|Caulobacterales 204458|Caulobacterales S Protein conserved in bacteria - - - - - - - - - - - - - TGS3_k127_5462030_4 1126627.BAWE01000005_gene5523 2.505e-23 102.0 2E6S2@1|root,331C5@2|Bacteria,1RH06@1224|Proteobacteria,2U98E@28211|Alphaproteobacteria,3K6MG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_5462030_2 1280950.HJO_16827 2.52e-80 278.0 COG0457@1|root,COG1262@1|root,COG0457@2|Bacteria,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,2U2VJ@28211|Alphaproteobacteria,43ZFH@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,Guanylate_cyc,TIR_2 TGS3_k127_5477855_0 1168059.KB899087_gene3429 1.287e-117 383.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2TRH3@28211|Alphaproteobacteria,3EY65@335928|Xanthobacteraceae 28211|Alphaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 TGS3_k127_5477855_1 754035.Mesau_02112 4.208e-95 319.0 COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,2TRPN@28211|Alphaproteobacteria,43IBA@69277|Phyllobacteriaceae 28211|Alphaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short TGS3_k127_5477855_2 231434.JQJH01000023_gene1535 2.535e-40 151.0 COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2UBRZ@28211|Alphaproteobacteria,3NBDJ@45404|Beijerinckiaceae 28211|Alphaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 TGS3_k127_5477855_5 743299.Acife_1544 2.151e-18 86.0 COG4710@1|root,COG4710@2|Bacteria,1PWUP@1224|Proteobacteria,1T99K@1236|Gammaproteobacteria,2NE2B@225057|Acidithiobacillales 225057|Acidithiobacillales S TraY domain - - - ko:K18918 - - - - ko00000,ko02048,ko03000 - - - TraY TGS3_k127_5477855_3 1509405.GV67_01060 4.253e-26 109.0 COG2026@1|root,COG2026@2|Bacteria,1N76D@1224|Proteobacteria,2UF77@28211|Alphaproteobacteria,4BM0G@82115|Rhizobiaceae 28211|Alphaproteobacteria DJ ParE toxin of type II toxin-antitoxin system, parDE - - - ko:K06218 - - - - ko00000,ko02048 - - - ParE_toxin TGS3_k127_5477855_4 1247963.JPHU01000011_gene714 7.642e-19 90.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2TSJK@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N TGS3_k127_5488907_1 1120956.JHZK01000019_gene2490 1.743e-56 205.0 2DZZ5@1|root,32VNT@2|Bacteria,1R6EA@1224|Proteobacteria,2UFTZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - DUF2269 TGS3_k127_5488907_0 640512.BC1003_0202 6.635e-137 443.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,1JZW5@119060|Burkholderiaceae 28216|Betaproteobacteria I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N TGS3_k127_5504937_4 314260.PB2503_12844 9.562e-30 121.0 COG3784@1|root,COG3784@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1318) ydbL - - ko:K09978 - - - - ko00000 - - - DUF1318 TGS3_k127_5504937_5 1282876.BAOK01000001_gene1117 1.532e-13 76.0 2E371@1|root,32Y6T@2|Bacteria,1N8D8@1224|Proteobacteria,2UGA5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S YnbE-like lipoprotein - - - - - - - - - - - - Lipoprotein_19 TGS3_k127_5504937_0 1247963.JPHU01000004_gene595 6.907e-104 372.0 COG2911@1|root,COG2911@2|Bacteria,1N08J@1224|Proteobacteria,2UE2C@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Dicarboxylate transport - - - - - - - - - - - - DctA-YdbH TGS3_k127_5504937_1 582402.Hbal_0140 1.926e-101 353.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TT3Z@28211|Alphaproteobacteria,43W9T@69657|Hyphomonadaceae 28211|Alphaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases nlpD2 - - - - - - - - - - - Peptidase_M23 TGS3_k127_5504937_3 1280941.HY2_15890 3.313e-49 181.0 COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,2TQWY@28211|Alphaproteobacteria,43YD2@69657|Hyphomonadaceae 28211|Alphaproteobacteria S NnrU protein nnrU - - - - - - - - - - - NnrU TGS3_k127_5504937_2 288000.BBta_2310 2.009e-78 267.0 COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,2TV7J@28211|Alphaproteobacteria,3JQWV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran TGS3_k127_5529455_0 1247963.JPHU01000001_gene2044 1.635e-163 520.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TR8H@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes lpd GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim TGS3_k127_5529455_1 329726.AM1_3156 1.269e-26 124.0 28KGE@1|root,2ZA27@2|Bacteria,1GDV9@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - TGS3_k127_5538970_1 114615.BRADO1951 1.311e-26 112.0 COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,1MU50@1224|Proteobacteria,2TRKE@28211|Alphaproteobacteria,3JS27@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K transcriptional regulator, XRE family MA20_44725 - - ko:K07110 - - - - ko00000,ko03000 - - - DUF2083,HTH_3,HTH_31,Peptidase_M78 TGS3_k127_5538970_0 1333998.M2A_1409 1.194e-228 713.0 COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,2TU0Q@28211|Alphaproteobacteria,4BP9R@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Phosphoenolpyruvate phosphomutase aceA - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL,PEP_mutase TGS3_k127_5539082_0 1123503.KB908056_gene1281 5.566e-176 566.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSUQ@28211|Alphaproteobacteria,2KFHP@204458|Caulobacterales 204458|Caulobacterales S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 TGS3_k127_5539082_1 314266.SKA58_14052 1.355e-108 360.0 COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,1MU50@1224|Proteobacteria,2TRKE@28211|Alphaproteobacteria,2K126@204457|Sphingomonadales 204457|Sphingomonadales K Transcriptional regulator - - - ko:K07110 - - - - ko00000,ko03000 - - - DUF2083,HTH_19,HTH_3,HTH_31,Peptidase_M78 TGS3_k127_5544099_0 40571.JOEA01000007_gene6653 5.991e-144 474.0 COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4DZPP@85010|Pseudonocardiales 201174|Actinobacteria I Acetyl propionyl-CoA carboxylase, alpha subunit accA1 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.4.1.2,6.4.1.3 ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00741 R00742,R01859,R04385 RC00040,RC00097,RC00253,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2501c Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 TGS3_k127_563878_4 228405.HNE_1708 1.046e-06 53.0 COG5569@1|root,COG5569@2|Bacteria 2|Bacteria P Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K07810 ko02020,map02020 - - - ko00000,ko00001 2.A.6.1.4 - - CusF_Ec TGS3_k127_563878_3 228405.HNE_1708 1.028e-13 74.0 COG5569@1|root,COG5569@2|Bacteria 2|Bacteria P Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K07810 ko02020,map02020 - - - ko00000,ko00001 2.A.6.1.4 - - CusF_Ec TGS3_k127_563878_2 1038860.AXAP01000011_gene262 1.917e-16 91.0 COG0392@1|root,COG0392@2|Bacteria,1MVZ8@1224|Proteobacteria,2TTDM@28211|Alphaproteobacteria,3JS9U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM TGS3_k127_563878_1 1128427.KB904821_gene3303 4.061e-67 248.0 COG3379@1|root,COG3379@2|Bacteria 2|Bacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest TGS3_k127_563878_0 1280954.HPO_01642 3.742e-190 604.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2TRMJ@28211|Alphaproteobacteria,43XA2@69657|Hyphomonadaceae 28211|Alphaproteobacteria L ATP-dependent helicase HrpB hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C TGS3_k127_5649518_0 1333998.M2A_1138 7.001e-69 240.0 COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2U59K@28211|Alphaproteobacteria,4BQ87@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine aat GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 ko:K00684 - - R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 - - - Leu_Phe_trans TGS3_k127_5649518_5 1333998.M2A_1140 3.223e-32 131.0 COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2UCHU@28211|Alphaproteobacteria,4BQI6@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria Q MlaD protein mlaD - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD TGS3_k127_5649518_2 314260.PB2503_11029 1.271e-48 178.0 COG3761@1|root,COG3761@2|Bacteria,1RHS3@1224|Proteobacteria,2U95G@28211|Alphaproteobacteria 28211|Alphaproteobacteria C NADH ubiquinone oxidoreductase 17.2 kD subunit MA20_29090 - 1.6.99.3 ko:K00356 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - NDUFA12 TGS3_k127_5649518_1 983917.RGE_21340 8.982e-61 213.0 COG3791@1|root,COG3791@2|Bacteria,1RFBP@1224|Proteobacteria,2VQN8@28216|Betaproteobacteria 28216|Betaproteobacteria S PFAM glutathione-dependent formaldehyde-activating GFA - - - - - - - - - - - - GFA TGS3_k127_5649518_4 639283.Snov_0887 6.021e-37 154.0 COG1487@1|root,COG1487@2|Bacteria,1MZB6@1224|Proteobacteria,2UEUU@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - ko:K18828 - - - - ko00000,ko01000,ko02048,ko03016 - - - PIN TGS3_k127_5649518_6 314278.NB231_15943 4.713e-19 88.0 COG4456@1|root,COG4456@2|Bacteria,1N85E@1224|Proteobacteria,1SE5A@1236|Gammaproteobacteria,1X1SK@135613|Chromatiales 135613|Chromatiales S Antidote-toxin recognition MazE, bacterial antitoxin - - - ko:K18829 - - - - ko00000,ko02048 - - - - TGS3_k127_5649518_3 412597.AEPN01000002_gene2691 2.515e-46 170.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS2I@28211|Alphaproteobacteria,2PV6D@265|Paracoccus 28211|Alphaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdJ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_2_N,Ribonuc_red_lgC TGS3_k127_5691143_2 666685.R2APBS1_1373 2.077e-76 263.0 COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,1RPFW@1236|Gammaproteobacteria,1X4ZQ@135614|Xanthomonadales 135614|Xanthomonadales I Belongs to the type-B carboxylesterase lipase family - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase TGS3_k127_5691143_0 59538.XP_005978883.1 8.316e-195 619.0 COG2072@1|root,KOG1399@2759|Eukaryota,39RHS@33154|Opisthokonta 33154|Opisthokonta Q monooxygenase - - - - - - - - - - - - FMO-like,NAD_binding_8,Pyr_redox_3 TGS3_k127_5691143_3 1280947.HY30_14260 4.906e-76 271.0 COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,2U2AI@28211|Alphaproteobacteria,43WR9@69657|Hyphomonadaceae 28211|Alphaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins - - 3.5.2.6 ko:K01467 ko01501,ko02020,map01501,map02020 M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000 - - - Beta-lactamase TGS3_k127_5691143_4 1519464.HY22_08540 5.753e-54 207.0 COG2819@1|root,COG2819@2|Bacteria 2|Bacteria S hydrolase activity, acting on ester bonds - - - - - - - - - - - - Esterase TGS3_k127_5691143_1 652103.Rpdx1_4081 2.506e-117 388.0 COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria,3JZ7D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Integrase core domain - - - - - - - - - - - - HTH_38,rve TGS3_k127_5712138_11 1280944.HY17_04280 1.501e-08 58.0 COG3293@1|root,COG3293@2|Bacteria,1RD4U@1224|Proteobacteria,2U9S3@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_2 TGS3_k127_5712138_2 1229204.AMYY01000010_gene596 1.434e-129 428.0 COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,2TSPF@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Major Facilitator Superfamily - - - ko:K02429 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 TGS3_k127_5712138_1 377629.TERTU_3750 2.669e-247 781.0 COG1472@1|root,COG2755@1|root,COG1472@2|Bacteria,COG2755@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,2PPXV@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria EG Glycosyl hydrolase family 3 C-terminal domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - CBM_6,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,Lipase_GDSL_2 TGS3_k127_5712138_0 394221.Mmar10_0246 2.03e-307 967.0 COG1629@1|root,COG1629@2|Bacteria,1MXTU@1224|Proteobacteria,2TS0H@28211|Alphaproteobacteria 28211|Alphaproteobacteria P TonB-dependent Receptor Plug Domain - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec TGS3_k127_5712138_3 1123257.AUFV01000001_gene1940 9.433e-79 275.0 COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN2K@1236|Gammaproteobacteria,1X3V1@135614|Xanthomonadales 135614|Xanthomonadales K transcriptional - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 TGS3_k127_5712138_4 1122137.AQXF01000002_gene653 1.472e-76 274.0 COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,2U8DJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Sugar glycoside-pentoside-hexuronide - - - ko:K03292 - - - - ko00000 2.A.2 - - MFS_2 TGS3_k127_5712138_13 1569209.BBPH01000206_gene674 8.844e-06 51.0 COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,2UBQE@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Transposase - - - ko:K07497 - - - - ko00000 - - - HTH_Tnp_1 TGS3_k127_5712138_7 572477.Alvin_0308 1.571e-55 206.0 COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1PGAZ@1224|Proteobacteria,1RWZ6@1236|Gammaproteobacteria,1X0SN@135613|Chromatiales 135613|Chromatiales T diguanylate cyclase - - - - - - - - - - - - GGDEF,PAS_9 TGS3_k127_5712138_5 1110502.TMO_1915 3.545e-67 256.0 COG0784@1|root,COG2198@1|root,COG3275@1|root,COG4251@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG3275@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria,2TW49@28211|Alphaproteobacteria,2JZ1E@204441|Rhodospirillales 204441|Rhodospirillales T Hpt domain - - - - - - - - - - - - Hpt,Response_reg TGS3_k127_5712138_9 1267005.KB911258_gene415 3.318e-21 100.0 28I3D@1|root,2Z876@2|Bacteria,1P0DR@1224|Proteobacteria,2TTG2@28211|Alphaproteobacteria,3N757@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S PilZ domain MA20_31715 - - - - - - - - - - - PilZ TGS3_k127_5712138_12 1280953.HOC_13344 2.191e-07 57.0 COG3916@1|root,COG3916@2|Bacteria,1RB3V@1224|Proteobacteria,2TV0R@28211|Alphaproteobacteria,4409K@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Autoinducer synthase - - 2.3.1.184,2.3.1.228,2.3.1.229 ko:K13060,ko:K18096 ko00270,ko01100,ko02024,ko02025,map00270,map01100,map02024,map02025 - R08940 RC00021,RC00039 ko00000,ko00001,ko01000 - - - Autoind_synth TGS3_k127_5712138_6 1396141.BATP01000022_gene241 6.744e-67 246.0 2DB7W@1|root,2Z7P1@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4331) - - - - - - - - - - - - DUF4331 TGS3_k127_5712138_8 1449351.RISW2_02135 3.062e-45 171.0 COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,2U6J3@28211|Alphaproteobacteria,4KK85@93682|Roseivivax 28211|Alphaproteobacteria K the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription MA20_09680 - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 TGS3_k127_5712138_10 1144343.PMI41_00991 1.062e-08 65.0 COG5343@1|root,COG5343@2|Bacteria,1N821@1224|Proteobacteria,2UF3V@28211|Alphaproteobacteria,43QTW@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Anti-sigma-K factor rskA - - - - - - - - - - - - RskA TGS3_k127_5750394_3 1280941.HY2_12850 2.079e-66 230.0 COG3045@1|root,COG3045@2|Bacteria,1RDMP@1224|Proteobacteria,2U72F@28211|Alphaproteobacteria,440SN@69657|Hyphomonadaceae 28211|Alphaproteobacteria S CreA protein creA - - ko:K05805 - - - - ko00000 - - - CreA TGS3_k127_5750394_6 794903.OPIT5_26865 4.088e-26 110.0 COG4634@1|root,COG4634@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - TGS3_k127_5750394_7 240292.Ava_3038 1.417e-21 95.0 COG2442@1|root,COG2442@2|Bacteria,1G7SB@1117|Cyanobacteria,1HPQ3@1161|Nostocales 1117|Cyanobacteria S Protein of unknown function (DUF433) - - - - - - - - - - - - DUF433 TGS3_k127_5750394_1 1280950.HJO_09524 1.043e-102 340.0 COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2TSVS@28211|Alphaproteobacteria,43WMF@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid gloB - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - HAGH_C,Lactamase_B TGS3_k127_5750394_4 1122963.AUHB01000004_gene3156 1.014e-64 230.0 COG0500@1|root,COG2226@2|Bacteria,1NA7K@1224|Proteobacteria,2TT7T@28211|Alphaproteobacteria,36XZZ@31993|Methylocystaceae 28211|Alphaproteobacteria Q Methyltransferase domain MA20_39625 - - - - - - - - - - - Methyltransf_11 TGS3_k127_5750394_2 395965.Msil_1209 1.6e-99 335.0 COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2TS12@28211|Alphaproteobacteria,3NAB0@45404|Beijerinckiaceae 28211|Alphaproteobacteria E Prephenate dehydrogenase tyrC GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 ko:K00210,ko:K00220,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025,M00040 R00732,R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH TGS3_k127_5750394_5 1149133.ppKF707_2653 2.772e-32 138.0 2DR3S@1|root,33A1K@2|Bacteria,1QYKB@1224|Proteobacteria 1224|Proteobacteria S Sulphur transport - - - ko:K07112,ko:K19168 - - - - ko00000,ko02048 - - - Sulf_transp TGS3_k127_5750394_0 314260.PB2503_02622 7.762e-250 777.0 COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,2TRJG@28211|Alphaproteobacteria 28211|Alphaproteobacteria S SpoVR family - - - ko:K06415 - - - - ko00000 - - - SpoVR TGS3_k127_5755808_0 1122962.AULH01000006_gene3328 5.085e-192 613.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2TRUB@28211|Alphaproteobacteria,36XRX@31993|Methylocystaceae 28211|Alphaproteobacteria L DNA polymerase alpha chain like domain dnaE2 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon TGS3_k127_5755808_1 639283.Snov_4406 5.094e-37 141.0 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2TQVR@28211|Alphaproteobacteria,3EYTR@335928|Xanthobacteraceae 28211|Alphaproteobacteria L Nucleotidyltransferase DNA polymerase involved in DNA repair MA20_15945 - - ko:K14161 - - - - ko00000,ko03400 - - - IMS,IMS_C TGS3_k127_5758509_2 1333998.M2A_0640 1.026e-92 311.0 COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2TQY8@28211|Alphaproteobacteria,4BQ6B@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate ate GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 ko:K21420 - - R11547,R11548 RC00064 ko00000,ko01000 - - - ATE_C,ATE_N TGS3_k127_5758509_1 1247963.JPHU01000003_gene1294 1.07e-155 499.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS4J@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP TGS3_k127_5758509_3 1122929.KB908221_gene2841 1.108e-40 161.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2U75U@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ TGS3_k127_5758509_0 1247963.JPHU01000003_gene1296 1.302e-194 620.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q TRAP-type mannitol chloroaromatic compound transport system large permease component - - - - - - - - - - - - DctM TGS3_k127_5758509_4 314254.OA2633_01841 1.141e-19 89.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2TS3N@28211|Alphaproteobacteria,43X2J@69657|Hyphomonadaceae 28211|Alphaproteobacteria O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 TGS3_k127_5761839_6 314271.RB2654_07781 1.054e-15 81.0 2EBV0@1|root,335UG@2|Bacteria,1NETE@1224|Proteobacteria,2UF5H@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_5761839_3 1035191.HMPREF0185_01092 9.217e-43 168.0 COG1595@1|root,COG1595@2|Bacteria,1PBHM@1224|Proteobacteria,2UB0K@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 TGS3_k127_5761839_0 551789.ATVJ01000002_gene3189 1.685e-159 519.0 COG3930@1|root,COG3930@2|Bacteria,1PYFH@1224|Proteobacteria,2U3X3@28211|Alphaproteobacteria,43WY4@69657|Hyphomonadaceae 28211|Alphaproteobacteria S DUF1704 - - - - - - - - - - - - DUF1704 TGS3_k127_5761839_7 1125973.JNLC01000013_gene3977 9.961e-06 56.0 2DRAN@1|root,33AZ6@2|Bacteria,1NJ5P@1224|Proteobacteria,2UMAM@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_5761839_5 1346791.M529_07045 1.968e-21 103.0 2919Q@1|root,2ZNWS@2|Bacteria,1NAF5@1224|Proteobacteria,2U3AC@28211|Alphaproteobacteria,2KEWN@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - TGS3_k127_5761839_4 1122137.AQXF01000003_gene2250 1.682e-22 111.0 COG4219@1|root,COG4219@2|Bacteria 2|Bacteria - - - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - LysM,PD40 TGS3_k127_5761839_1 1247963.JPHU01000012_gene914 8.402e-149 481.0 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2TQZX@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b TGS3_k127_5761839_2 1247963.JPHU01000003_gene1470 2.566e-108 363.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2TS44@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN TGS3_k127_5827084_4 314260.PB2503_10319 2.919e-10 64.0 COG5490@1|root,COG5490@2|Bacteria 2|Bacteria S Phasin protein MA20_36110 - - - - - - - - - - - Phasin_2 TGS3_k127_5827084_2 1247963.JPHU01000014_gene1011 6.435e-48 174.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2U982@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS - - ko:K06891 - - - - ko00000 - - - ClpS TGS3_k127_5827084_0 1161401.ASJA01000001_gene538 0.0 1135.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2TQUZ@28211|Alphaproteobacteria,43WNG@69657|Hyphomonadaceae 28211|Alphaproteobacteria O Belongs to the ClpA ClpB family clpA GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N TGS3_k127_5827084_3 1122176.KB903531_gene3085 7.551e-30 122.0 COG4430@1|root,COG4430@2|Bacteria,4NKNI@976|Bacteroidetes,1ITNC@117747|Sphingobacteriia 976|Bacteroidetes S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - DUF1801,OmdA TGS3_k127_5827084_1 314260.PB2503_02347 6.282e-261 811.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2TRHX@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey TGS3_k127_5830684_2 465541.ATCJ01000005_gene2138 8.305e-67 233.0 COG2173@1|root,COG2173@2|Bacteria,2GK5P@201174|Actinobacteria 201174|Actinobacteria M Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - Peptidase_M15 TGS3_k127_5830684_0 1123267.JONN01000001_gene1174 6.83e-161 515.0 COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TSW9@28211|Alphaproteobacteria,2K0RE@204457|Sphingomonadales 204457|Sphingomonadales L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K13581 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko02048 - - - N6_N4_Mtase TGS3_k127_5830684_3 1380367.JIBC01000005_gene3061 2.432e-62 226.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,3ZWU9@60136|Sulfitobacter 28211|Alphaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII TGS3_k127_5830684_1 314260.PB2503_02087 1.221e-126 415.0 COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2TQQB@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Radical SAM MA20_42330 - - - - - - - - - - - Radical_SAM TGS3_k127_5832740_3 228405.HNE_2999 8.467e-11 65.0 COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,2TSK9@28211|Alphaproteobacteria,43WCB@69657|Hyphomonadaceae 28211|Alphaproteobacteria P Outer membrane receptor - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec TGS3_k127_5832740_0 1292034.OR37_00439 3.194e-55 209.0 COG2807@1|root,COG2807@2|Bacteria,1NS7T@1224|Proteobacteria,2U191@28211|Alphaproteobacteria,2KI7T@204458|Caulobacterales 204458|Caulobacterales P PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 TGS3_k127_5832740_1 69395.JQLZ01000005_gene3840 1.287e-18 89.0 COG4773@1|root,COG4773@2|Bacteria,1NXPR@1224|Proteobacteria,2U161@28211|Alphaproteobacteria,2KICT@204458|Caulobacterales 204458|Caulobacterales P TonB-dependent Receptor Plug - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec TGS3_k127_5832740_2 1123269.NX02_16085 4.693e-14 77.0 COG4774@1|root,COG4774@2|Bacteria,1QVD5@1224|Proteobacteria,2TYW1@28211|Alphaproteobacteria 28211|Alphaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug TGS3_k127_5853574_2 1121123.AUAO01000003_gene2319 1.541e-45 177.0 COG1196@1|root,COG1196@2|Bacteria,1R9KB@1224|Proteobacteria,2UEBY@28211|Alphaproteobacteria,2KIP2@204458|Caulobacterales 204458|Caulobacterales D Domain of unknown function (DUF4349) - - - - - - - - - - - - DUF4349 TGS3_k127_5853574_1 1122137.AQXF01000005_gene1107 9.535e-93 314.0 COG5285@1|root,COG5285@2|Bacteria,1Q78R@1224|Proteobacteria,2TSX3@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Phytanoyl-CoA dioxygenase (PhyH) - - - - - - - - - - - - PhyH TGS3_k127_5853574_3 551275.KB899546_gene2112 2.052e-26 117.0 2AINY@1|root,3195E@2|Bacteria,1Q1UT@1224|Proteobacteria,2V9GK@28211|Alphaproteobacteria,440M6@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_5853574_0 402881.Plav_2665 4.637e-119 390.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2TQQ1@28211|Alphaproteobacteria,1JN1E@119043|Rhodobiaceae 28211|Alphaproteobacteria J DALR_2 cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e TGS3_k127_5856529_0 1247963.JPHU01000004_gene455 6.704e-183 580.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase TGS3_k127_5856529_3 1247963.JPHU01000004_gene454 3.319e-49 179.0 2CN5Z@1|root,32SGB@2|Bacteria,1N1FB@1224|Proteobacteria,2UBV1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2948) MA20_21100 - - - - - - - - - - - DUF2948 TGS3_k127_5856529_2 402881.Plav_0522 1.303e-55 200.0 COG5328@1|root,COG5328@2|Bacteria,1RA93@1224|Proteobacteria,2U741@28211|Alphaproteobacteria,1JNVW@119043|Rhodobiaceae 28211|Alphaproteobacteria S Uncharacterised protein family (UPF0262) MA20_21090 - - - - - - - - - - - UPF0262 TGS3_k127_5856529_5 1247963.JPHU01000009_gene2383 3.807e-34 135.0 COG0394@1|root,COG0394@2|Bacteria,1RANV@1224|Proteobacteria,2U5EE@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Belongs to the low molecular weight phosphotyrosine protein phosphatase family MA20_21085 - 1.20.4.1,3.1.3.48 ko:K01104,ko:K03741 - - - - ko00000,ko01000 - - - LMWPc TGS3_k127_5856529_4 1207058.L53_03235 2.323e-35 135.0 COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2UBRU@28211|Alphaproteobacteria,43Y6G@69657|Hyphomonadaceae 28211|Alphaproteobacteria J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA - - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a TGS3_k127_5856529_1 1282876.BAOK01000001_gene3147 8.868e-62 218.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2TSS5@28211|Alphaproteobacteria,4BQAD@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria D Maf-like protein maf - - ko:K06287 - - - - ko00000 - - - Maf TGS3_k127_5856529_7 1479238.JQMZ01000001_gene2524 9.383e-12 78.0 COG1530@1|root,COG1530@2|Bacteria,1MWBR@1224|Proteobacteria,2UDR9@28211|Alphaproteobacteria,440ZE@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Ribonuclease E/G family - - - - - - - - - - - - RNase_E_G TGS3_k127_5856529_6 1211115.ALIQ01000002_gene4362 3.661e-14 76.0 COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,2UJJF@28211|Alphaproteobacteria,3NBUF@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase yacG - - ko:K09862 - - - - ko00000 - - - YacG TGS3_k127_5892091_5 1247963.JPHU01000004_gene518 3.757e-25 113.0 COG1702@1|root,COG1702@2|Bacteria,1MWMU@1224|Proteobacteria,2TSYC@28211|Alphaproteobacteria 28211|Alphaproteobacteria T phosphate starvation-inducible protein PhoH - - - ko:K06217 - - - - ko00000 - - - PhoH TGS3_k127_5892091_0 1247963.JPHU01000013_gene705 1.062e-50 186.0 2E7JJ@1|root,3321R@2|Bacteria,1N9EY@1224|Proteobacteria,2UF3Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_5892091_3 1247963.JPHU01000013_gene706 4.27e-32 135.0 28I3D@1|root,2Z876@2|Bacteria,1P0DR@1224|Proteobacteria,2TTG2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM type IV pilus assembly PilZ MA20_31715 - - - - - - - - - - - PilZ TGS3_k127_5892091_4 1267005.KB911258_gene417 1.471e-30 130.0 COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria,3N92E@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Rhomboid family MA20_31620 - - - - - - - - - - - Rhomboid TGS3_k127_5892091_2 935840.JAEQ01000002_gene3635 1.482e-37 147.0 COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2UC0F@28211|Alphaproteobacteria,43JZ1@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S CBS domain MA20_31615 - - - - - - - - - - - CBS TGS3_k127_5892091_1 1517416.IDAT_02345 2.553e-47 176.0 COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,1RSMY@1236|Gammaproteobacteria,2QGFZ@267893|Idiomarinaceae 1236|Gammaproteobacteria M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - - - - - - - - - - Fasciclin TGS3_k127_5892091_6 4113.PGSC0003DMT400052301 5.527e-08 57.0 2E4EA@1|root,2S5QZ@2759|Eukaryota,37X8Y@33090|Viridiplantae,3GKGJ@35493|Streptophyta,44UAV@71274|asterids 35493|Streptophyta - - - - - - - - - - - - - - - TGS3_k127_5907105_3 380358.XALC_2685 1.309e-12 72.0 COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,1RY8J@1236|Gammaproteobacteria,1X391@135614|Xanthomonadales 135614|Xanthomonadales Q ABC transporter substrate-binding protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD TGS3_k127_5907105_1 1247963.JPHU01000005_gene413 2.314e-27 120.0 COG3218@1|root,COG3218@2|Bacteria,1NFVA@1224|Proteobacteria,2UGJ6@28211|Alphaproteobacteria 28211|Alphaproteobacteria S ABC-type transport auxiliary lipoprotein component - - - ko:K18480 - M00669 - - ko00000,ko00002,ko02000 3.A.1.27.1 - - ABC_trans_aux TGS3_k127_5907105_2 588932.JHOF01000023_gene1893 3.168e-21 96.0 COG1476@1|root,COG1476@2|Bacteria,1N4N3@1224|Proteobacteria,2UCD9@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_31 TGS3_k127_5907105_0 595536.ADVE02000001_gene1858 5.247e-160 518.0 COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,2U1TN@28211|Alphaproteobacteria,3701H@31993|Methylocystaceae 28211|Alphaproteobacteria S HipA-like C-terminal domain - - 2.7.11.1 ko:K07154 - - - - ko00000,ko01000,ko01001,ko02048 - - - Couple_hipA,HipA_C TGS3_k127_5907105_4 1247963.JPHU01000005_gene412 6.336e-09 59.0 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - 4.2.2.1 ko:K01727 - - - - ko00000,ko01000 - PL8 - - TGS3_k127_5984463_1 1479238.JQMZ01000001_gene1629 9.942e-116 375.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria,43WP4@69657|Hyphomonadaceae 28211|Alphaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV TGS3_k127_5984463_0 1122137.AQXF01000006_gene742 1.669e-233 745.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2U2UK@28211|Alphaproteobacteria 28211|Alphaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec TGS3_k127_5984463_2 1085623.GNIT_0280 1.474e-48 177.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_19,TPR_8 TGS3_k127_5988103_1 1121949.AQXT01000002_gene2933 6.539e-183 597.0 COG4774@1|root,COG4774@2|Bacteria,1QVG7@1224|Proteobacteria,2TV9I@28211|Alphaproteobacteria,43X7G@69657|Hyphomonadaceae 28211|Alphaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec TGS3_k127_5988103_0 1267005.KB911256_gene1897 2.885e-264 820.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2TQM7@28211|Alphaproteobacteria,3N65K@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 TGS3_k127_6010733_2 1122137.AQXF01000004_gene1627 6.561e-26 111.0 COG3695@1|root,COG3695@2|Bacteria,1PZ1R@1224|Proteobacteria,2UWVB@28211|Alphaproteobacteria 28211|Alphaproteobacteria L 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - - - - - - - - - - DNA_binding_1 TGS3_k127_6010733_0 394221.Mmar10_2904 5.028e-73 252.0 COG0693@1|root,COG0693@2|Bacteria,1N8N6@1224|Proteobacteria,2TT0U@28211|Alphaproteobacteria,43XK4@69657|Hyphomonadaceae 28211|Alphaproteobacteria S intracellular protease amidase - - 4.2.1.103 ko:K18199 ko00930,map00930 - R05771 RC01467 ko00000,ko00001,ko01000,ko01002 - - - DJ-1_PfpI TGS3_k127_6010733_1 382464.ABSI01000007_gene4066 1.312e-53 194.0 COG2930@1|root,COG2930@2|Bacteria,46W27@74201|Verrucomicrobia,2IWC8@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Las17-binding protein actin regulator - - - - - - - - - - - - Ysc84 TGS3_k127_6032103_1 1411685.U062_02158 3.415e-72 254.0 COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,1RQ26@1236|Gammaproteobacteria,1J8GH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Metallo-beta-lactamase superfamily attM - 3.1.1.81 ko:K13075 ko02024,map02024 - R08970 RC00713 ko00000,ko00001,ko01000 - - - Lactamase_B TGS3_k127_6032103_3 598659.NAMH_1184 1.128e-09 61.0 2AY0S@1|root,31Q2B@2|Bacteria,1QMQY@1224|Proteobacteria,42SY0@68525|delta/epsilon subdivisions,2YPGA@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S Bacteriophage replication gene A protein (GPA) - - - - - - - - - - - - Phage_GPA TGS3_k127_6032103_4 392499.Swit_1458 0.000792 50.0 COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,2UQU5@28211|Alphaproteobacteria,2K2WY@204457|Sphingomonadales 204457|Sphingomonadales N flagellar motor switch protein fliM - - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C TGS3_k127_6032103_0 1280946.HY29_06715 3.773e-81 279.0 COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,2TTW2@28211|Alphaproteobacteria,43W4M@69657|Hyphomonadaceae 28211|Alphaproteobacteria N chemotaxis MotB protein motB - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA TGS3_k127_6032103_2 1280947.HY30_04690 7.979e-39 149.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,2TSF2@28211|Alphaproteobacteria,43X4Y@69657|Hyphomonadaceae 28211|Alphaproteobacteria N Flagellar hook protein FlgE flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C TGS3_k127_6036646_6 1411123.JQNH01000001_gene3752 1.348e-52 190.0 COG3760@1|root,COG3760@2|Bacteria,1RDIG@1224|Proteobacteria,2U87T@28211|Alphaproteobacteria 28211|Alphaproteobacteria S YbaK prolyl-tRNA synthetase - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit TGS3_k127_6036646_1 1247963.JPHU01000002_gene2600 6.355e-89 303.0 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2TS5X@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Thioredoxin trxA2 - - ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - TPR_19,TPR_20,Thioredoxin TGS3_k127_6036646_3 1449049.JONW01000005_gene1767 2.096e-65 234.0 COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,2TQZ4@28211|Alphaproteobacteria,2KGDQ@204458|Caulobacterales 204458|Caulobacterales S Peptidase S16, lon domain protein - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg TGS3_k127_6036646_10 1380394.JADL01000001_gene1999 8.91e-21 94.0 COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2UF4N@28211|Alphaproteobacteria,2JUCC@204441|Rhodospirillales 204441|Rhodospirillales S Belongs to the UPF0434 family - - - ko:K09791 - - - - ko00000 - - - Trm112p TGS3_k127_6036646_7 1247963.JPHU01000002_gene2553 1.423e-50 188.0 COG2834@1|root,COG2834@2|Bacteria,1RA1S@1224|Proteobacteria,2U58W@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA - - - - - - - - - - - LolA TGS3_k127_6036646_4 1247963.JPHU01000002_gene2552 4.474e-62 219.0 2BGD9@1|root,32AAZ@2|Bacteria,1RJNC@1224|Proteobacteria,2U9WN@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_6036646_5 935840.JAEQ01000011_gene1849 6.175e-56 204.0 COG0730@1|root,COG0730@2|Bacteria,1RAG9@1224|Proteobacteria,2VEQZ@28211|Alphaproteobacteria,43HE4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S membrane transporter protein - - - - - - - - - - - - TauE TGS3_k127_6036646_0 314260.PB2503_04102 2.227e-113 371.0 COG0708@1|root,COG0708@2|Bacteria,1MVMC@1224|Proteobacteria,2TRWQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Exodeoxyribonuclease III xthA2 - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos TGS3_k127_6036646_2 685778.AORL01000001_gene140 1.341e-84 298.0 COG0520@1|root,COG0520@2|Bacteria,1QU0N@1224|Proteobacteria,2TW6K@28211|Alphaproteobacteria,2KEC3@204457|Sphingomonadales 204457|Sphingomonadales E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 TGS3_k127_6036646_9 1280952.HJA_02405 7.822e-21 96.0 COG4095@1|root,COG4095@2|Bacteria,1N759@1224|Proteobacteria,2UG31@28211|Alphaproteobacteria,43YE7@69657|Hyphomonadaceae 28211|Alphaproteobacteria S PQ loop repeat - - - ko:K15383 - - - - ko00000,ko02000 9.A.58.2 - - PQ-loop TGS3_k127_6036646_8 1280954.HPO_14741 2.308e-48 176.0 COG0566@1|root,COG0566@2|Bacteria,1REIN@1224|Proteobacteria,2U76Y@28211|Alphaproteobacteria,43XRW@69657|Hyphomonadaceae 28211|Alphaproteobacteria J rRNA methyltransferase - - - - - - - - - - - - SpoU_methylase TGS3_k127_6049641_2 1247963.JPHU01000016_gene1066 3.923e-69 237.0 COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2U5B5@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 TGS3_k127_6049641_1 1502724.FF80_00746 2.735e-70 240.0 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2U5FM@28211|Alphaproteobacteria,3N6UC@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 TGS3_k127_6049641_0 1247963.JPHU01000016_gene1063 3.826e-82 284.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA TGS3_k127_6087581_9 1122132.AQYH01000003_gene3184 5.151e-15 75.0 COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,2TV6R@28211|Alphaproteobacteria,4BMCT@82115|Rhizobiaceae 28211|Alphaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold ligC - 1.1.1.312 ko:K10219 ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220 M00533 R04278,R04279,R04418,R04419 RC00251,RC00254 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C TGS3_k127_6087581_10 1197906.CAJQ02000003_gene3219 2.987e-09 63.0 COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JUGV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Resolvase - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom TGS3_k127_6087581_5 190650.CC_2654 2.053e-73 254.0 COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2U57X@28211|Alphaproteobacteria,2KGE5@204458|Caulobacterales 204458|Caulobacterales S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF TGS3_k127_6087581_4 1247963.JPHU01000003_gene1525 9.327e-77 266.0 COG0652@1|root,COG0652@2|Bacteria,1QCY4@1224|Proteobacteria,2U56N@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - Pro_isomerase TGS3_k127_6087581_6 331869.BAL199_21979 1.08e-54 200.0 COG0494@1|root,COG0494@2|Bacteria,1Q4Q6@1224|Proteobacteria,2UAME@28211|Alphaproteobacteria 28211|Alphaproteobacteria L NUDIX domain - - - - - - - - - - - - NUDIX TGS3_k127_6087581_0 314260.PB2503_01772 9.801e-102 340.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2TQQ5@28211|Alphaproteobacteria 28211|Alphaproteobacteria E serine acetyltransferase cysE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,SATase_N TGS3_k127_6087581_7 1342301.JASD01000006_gene87 7.452e-25 111.0 COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2UN50@28211|Alphaproteobacteria,3ZXJ7@60136|Sulfitobacter 28211|Alphaproteobacteria S Copper chaperone PCu(A)C - - - - - - - - - - - - PCuAC TGS3_k127_6087581_8 631454.N177_2024 1.281e-19 93.0 2E4B6@1|root,32Z6W@2|Bacteria,1N7QS@1224|Proteobacteria,2UFNH@28211|Alphaproteobacteria,1JPEE@119043|Rhodobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF3126) MA20_32250 - - - - - - - - - - - DUF3126 TGS3_k127_6087581_3 1247963.JPHU01000004_gene579 3.148e-77 266.0 2D6JA@1|root,32TME@2|Bacteria,1MXVJ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - TGS3_k127_6087581_1 190650.CC_3179 2.064e-93 317.0 COG2159@1|root,COG2159@2|Bacteria,1PTY1@1224|Proteobacteria,2V5RF@28211|Alphaproteobacteria,2KHVI@204458|Caulobacterales 204458|Caulobacterales S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 TGS3_k127_6087581_2 1479238.JQMZ01000001_gene1327 5.847e-86 286.0 COG1702@1|root,COG1702@2|Bacteria,1MWMU@1224|Proteobacteria,2TSYC@28211|Alphaproteobacteria,43W8Q@69657|Hyphomonadaceae 28211|Alphaproteobacteria T COG1702 Phosphate starvation-inducible protein PhoH - - - ko:K06217 - - - - ko00000 - - - PhoH TGS3_k127_6096879_2 1120983.KB894574_gene1019 2.163e-40 162.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2TRK1@28211|Alphaproteobacteria,1JNWF@119043|Rhodobiaceae 28211|Alphaproteobacteria D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3 TGS3_k127_6096879_3 314260.PB2503_08299 1.181e-26 120.0 COG1729@1|root,COG1729@2|Bacteria 2|Bacteria S protein trimerization cpoB - - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri TGS3_k127_6096879_1 1088868.CIN_05070 3.446e-45 171.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2U758@28211|Alphaproteobacteria,2JSJ9@204441|Rhodospirillales 204441|Rhodospirillales M Belongs to the ompA family - - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA TGS3_k127_6096879_0 1247963.JPHU01000016_gene1039 8.521e-136 435.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N TGS3_k127_6119464_0 314260.PB2503_03387 5.653e-122 401.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2TSBK@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 TGS3_k127_6125194_0 317655.Sala_2328 0.0 1066.0 COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,2U1V9@28211|Alphaproteobacteria,2KEE4@204457|Sphingomonadales 204457|Sphingomonadales P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec TGS3_k127_6125194_5 292415.Tbd_0849 2.548e-30 128.0 2BIJA@1|root,32CS2@2|Bacteria,1RHJT@1224|Proteobacteria,2VT9T@28216|Betaproteobacteria 28216|Betaproteobacteria S CHRD domain - - - - - - - - - - - - CHRD,VPEP TGS3_k127_6125194_3 1282362.AEAC466_21025 2.907e-83 284.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,2TT7B@28211|Alphaproteobacteria,2KGGX@204458|Caulobacterales 204458|Caulobacterales P nucleotidase cysQ - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P TGS3_k127_6125194_2 1247963.JPHU01000005_gene385 2.95e-119 399.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2TRZA@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Sugar transferase - - - ko:K03606 ko05111,map05111 - - - ko00000,ko00001 - - - Bac_transf,CoA_binding_3 TGS3_k127_6125194_1 331869.BAL199_20155 4.871e-211 663.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,4BP98@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family rkpK - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N TGS3_k127_6125194_4 1247963.JPHU01000007_gene1604 4.151e-66 233.0 COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2U59A@28211|Alphaproteobacteria 28211|Alphaproteobacteria U UPF0056 membrane protein marC - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC TGS3_k127_6135745_2 314254.OA2633_00800 9.67e-28 119.0 COG1595@1|root,COG1595@2|Bacteria,1RD9G@1224|Proteobacteria,2U92K@28211|Alphaproteobacteria,43Y7E@69657|Hyphomonadaceae 28211|Alphaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 TGS3_k127_6135745_3 1161401.ASJA01000019_gene1171 3.099e-18 89.0 2DSPA@1|root,33GWY@2|Bacteria,1NNRJ@1224|Proteobacteria,2VGIS@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_6135745_0 1247963.JPHU01000004_gene515 1.202e-102 337.0 COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2TRMI@28211|Alphaproteobacteria 28211|Alphaproteobacteria S hydrolase of the alpha beta superfamily QU41_16170 - - ko:K07018 - - - - ko00000 - - - Hydrolase_4,Peptidase_S15 TGS3_k127_6135745_1 450851.PHZ_c1722 1.261e-40 156.0 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2U5B9@28211|Alphaproteobacteria,2KGVJ@204458|Caulobacterales 204458|Caulobacterales K Rrf2 family - - - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 TGS3_k127_6146262_6 686340.Metal_2782 4.128e-89 308.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN5K@1236|Gammaproteobacteria,1XETH@135618|Methylococcales 135618|Methylococcales MU PFAM Outer membrane efflux protein - - - ko:K18300 - M00641 - - ko00000,ko00002,ko01504,ko02000 1.B.17 - - OEP TGS3_k127_6146262_7 1247963.JPHU01000001_gene2087 1.489e-81 276.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2TRGI@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Outer membrane protein W ompW - - ko:K07275 - - - - ko00000 - - - OmpW TGS3_k127_6146262_5 316056.RPC_3814 1.397e-93 323.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2TRKT@28211|Alphaproteobacteria,3JVP6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN - - - - - - - - - - - HemN_C,Radical_SAM TGS3_k127_6146262_8 663932.KB902575_gene1656 7.034e-42 162.0 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2TV0E@28211|Alphaproteobacteria,2JRE3@204441|Rhodospirillales 204441|Rhodospirillales K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding TGS3_k127_6146262_0 1123503.KB908057_gene2482 9.386e-275 853.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2TR2C@28211|Alphaproteobacteria,2KFC3@204458|Caulobacterales 204458|Caulobacterales C Belongs to the heme-copper respiratory oxidase family ccoN - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 TGS3_k127_6146262_3 1121949.AQXT01000002_gene2821 6.454e-110 359.0 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2TRGW@28211|Alphaproteobacteria,43WE1@69657|Hyphomonadaceae 28211|Alphaproteobacteria C COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit ccoO - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixO TGS3_k127_6146262_10 1122613.ATUP01000001_gene1107 1.986e-13 71.0 COG4736@1|root,COG4736@2|Bacteria,1NGV0@1224|Proteobacteria,2UJBS@28211|Alphaproteobacteria,43YSC@69657|Hyphomonadaceae 28211|Alphaproteobacteria O Cbb3-type cytochrome oxidase component FixQ - - - ko:K00407 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixQ TGS3_k127_6146262_4 450851.PHZ_c2811 5.926e-103 344.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria,2KG0I@204458|Caulobacterales 204458|Caulobacterales C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N TGS3_k127_6146262_1 314254.OA2633_08309 1.587e-200 635.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2TRYB@28211|Alphaproteobacteria,43WKQ@69657|Hyphomonadaceae 28211|Alphaproteobacteria C Cytochrome c oxidase accessory protein ccoG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Fer4_18,Fer4_5,FixG_C TGS3_k127_6146262_9 1207058.L53_05125 1.183e-16 87.0 COG5456@1|root,COG5456@2|Bacteria,1RHKI@1224|Proteobacteria,2U9GB@28211|Alphaproteobacteria,43YIU@69657|Hyphomonadaceae 28211|Alphaproteobacteria P FixH fixH - - - - - - - - - - - FixH TGS3_k127_6146262_2 314254.OA2633_08319 1.214e-177 576.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,43WAW@69657|Hyphomonadaceae 28211|Alphaproteobacteria P COG2217 Cation transport ATPase fixI GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase TGS3_k127_6162689_0 1123267.JONN01000001_gene1238 1.616e-321 1009.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - Cupin_2,MRJP TGS3_k127_6184925_2 765698.Mesci_1546 1.415e-37 143.0 COG3558@1|root,COG3558@2|Bacteria,1RA64@1224|Proteobacteria,2U5FW@28211|Alphaproteobacteria,43K5W@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1348) - - - ko:K09958 - - - - ko00000 - - - DUF1348 TGS3_k127_6184925_1 1280950.HJO_11112 4.157e-73 252.0 COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2TTY5@28211|Alphaproteobacteria,43XTX@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity ahpD - - - - - - - - - - - CMD TGS3_k127_6184925_0 1247963.JPHU01000014_gene992 1.259e-160 522.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria 28211|Alphaproteobacteria P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - ko:K03455,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.2 - - Na_H_Exchanger,TrkA_N TGS3_k127_6191825_0 402881.Plav_0105 7.422e-284 888.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,1JN6G@119043|Rhodobiaceae 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 TGS3_k127_6191825_5 1123393.KB891326_gene34 6.211e-20 95.0 COG5455@1|root,COG5455@2|Bacteria,1RJ9A@1224|Proteobacteria,2VRVC@28216|Betaproteobacteria,1KT1I@119069|Hydrogenophilales 119069|Hydrogenophilales S response to cobalt ion - - - - - - - - - - - - - TGS3_k127_6191825_3 631454.N177_2692 1.797e-44 177.0 COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,2TTW2@28211|Alphaproteobacteria,1JPKG@119043|Rhodobiaceae 28211|Alphaproteobacteria N Membrane MotB of proton-channel complex MotA/MotB motB - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA TGS3_k127_6191825_2 631454.N177_2693 8.388e-77 265.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2TTXY@28211|Alphaproteobacteria 28211|Alphaproteobacteria N Flagellar motor component motA - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB TGS3_k127_6191825_1 391600.ABRU01000005_gene1634 2.328e-117 385.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2TS3N@28211|Alphaproteobacteria,2KG3X@204458|Caulobacterales 204458|Caulobacterales O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 TGS3_k127_6191825_6 450851.PHZ_c3503 1.277e-17 84.0 COG5508@1|root,COG5508@2|Bacteria,1N7D3@1224|Proteobacteria,2UF8M@28211|Alphaproteobacteria,2KHD7@204458|Caulobacterales 204458|Caulobacterales S Protein of unknown function (DUF1674) - - - - - - - - - - - - DUF1674 TGS3_k127_6191825_4 1121033.AUCF01000002_gene557 3.6e-25 110.0 COG1525@1|root,COG1525@2|Bacteria,1N0I9@1224|Proteobacteria,2UBYJ@28211|Alphaproteobacteria,2JTE8@204441|Rhodospirillales 204441|Rhodospirillales L COG1525 Micrococcal nuclease (thermonuclease) homologs - - - - - - - - - - - - SNase TGS3_k127_6191825_7 652103.Rpdx1_4081 6.318e-05 45.0 COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria,3JZ7D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Integrase core domain - - - - - - - - - - - - HTH_38,rve TGS3_k127_6191894_6 279238.Saro_1205 2.253e-19 91.0 COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,2TR1F@28211|Alphaproteobacteria,2K06J@204457|Sphingomonadales 204457|Sphingomonadales S COG0491 Zn-dependent hydrolases, including glyoxylases - - - - - - - - - - - - Lactamase_B TGS3_k127_6191894_5 1479238.JQMZ01000001_gene371 1.501e-30 124.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2UFSY@28211|Alphaproteobacteria,43YVS@69657|Hyphomonadaceae 28211|Alphaproteobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor bigR - - - - - - - - - - - HTH_20,HTH_5 TGS3_k127_6191894_4 1007104.SUS17_3089 3.291e-40 154.0 COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,2UCDT@28211|Alphaproteobacteria,2K723@204457|Sphingomonadales 204457|Sphingomonadales S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp TGS3_k127_6191894_3 391613.RTM1035_18685 1.708e-41 159.0 COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,2U99K@28211|Alphaproteobacteria,46QQA@74030|Roseovarius 28211|Alphaproteobacteria S transporter component - - - ko:K07112 - - - - ko00000 - - - Sulf_transp TGS3_k127_6191894_0 1040989.AWZU01000001_gene5708 0.0 1041.0 COG1657@1|root,COG1657@2|Bacteria,1MUIP@1224|Proteobacteria,2TRF3@28211|Alphaproteobacteria,3JRDS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Squalene-hopene cyclase C-terminal domain shc - 4.2.1.129,5.4.99.17 ko:K06045 ko00909,ko01110,map00909,map01110 - R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 - - - SQHop_cyclase_C,SQHop_cyclase_N TGS3_k127_6191894_1 1280944.HY17_00090 7.808e-83 284.0 COG3000@1|root,COG3000@2|Bacteria,1NXAF@1224|Proteobacteria,2U9R8@28211|Alphaproteobacteria,43Y6V@69657|Hyphomonadaceae 28211|Alphaproteobacteria I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase TGS3_k127_6191894_2 1280944.HY17_00085 1.652e-63 231.0 COG2207@1|root,COG2207@2|Bacteria,1P4M5@1224|Proteobacteria,2TSQV@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator, araC family - - - - - - - - - - - - HTH_18 TGS3_k127_6191894_7 652103.Rpdx1_4081 6.318e-05 45.0 COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria,3JZ7D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Integrase core domain - - - - - - - - - - - - HTH_38,rve TGS3_k127_6197123_3 1205680.CAKO01000040_gene818 1.395e-27 129.0 COG2242@1|root,COG2242@2|Bacteria,1QX6B@1224|Proteobacteria,2TZAR@28211|Alphaproteobacteria,2JUEP@204441|Rhodospirillales 204441|Rhodospirillales H Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 TGS3_k127_6197123_4 1385935.N836_29995 2.072e-07 64.0 COG2520@1|root,COG2520@2|Bacteria,1GA8M@1117|Cyanobacteria,1HDV5@1150|Oscillatoriales 1117|Cyanobacteria J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 TGS3_k127_6197123_2 551275.KB899550_gene627 3.394e-53 208.0 COG0438@1|root,COG0438@2|Bacteria,1PG8J@1224|Proteobacteria,2V8HG@28211|Alphaproteobacteria,43ZRW@69657|Hyphomonadaceae 28211|Alphaproteobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - TGS3_k127_6197123_0 941449.dsx2_1090 3.91e-74 270.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42WCU@68525|delta/epsilon subdivisions,2X5FB@28221|Deltaproteobacteria,2MGD0@213115|Desulfovibrionales 28221|Deltaproteobacteria M Glycosyl transferase 4-like domain - - - - - - - - - - - - - TGS3_k127_6197123_1 1417296.U879_03500 7.091e-55 208.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria 28211|Alphaproteobacteria E asparagine synthase asnO - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 TGS3_k127_6205834_0 861208.AGROH133_02924 4.125e-68 235.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2TSJK@28211|Alphaproteobacteria,4B8CH@82115|Rhizobiaceae 28211|Alphaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N TGS3_k127_6205834_2 1123229.AUBC01000014_gene2953 4.79e-56 201.0 COG1670@1|root,COG1670@2|Bacteria,1PS2X@1224|Proteobacteria,2UBB7@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Acetyltransferase (GNAT) domain - - 2.3.1.82 ko:K00663 - - - - ko00000,ko01000,ko01504 - - - Acetyltransf_8 TGS3_k127_6205834_5 582402.Hbal_3065 1.372e-37 148.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2UCJF@28211|Alphaproteobacteria,43Y3F@69657|Hyphomonadaceae 28211|Alphaproteobacteria J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA TGS3_k127_6205834_3 414684.RC1_3385 1.176e-48 183.0 COG0135@1|root,COG0135@2|Bacteria,1RA5Q@1224|Proteobacteria,2U5E8@28211|Alphaproteobacteria 28211|Alphaproteobacteria E N-(5'phosphoribosyl)anthranilate (PRA) isomerase - - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI TGS3_k127_6205834_1 1123366.TH3_17252 3.526e-59 210.0 COG1670@1|root,COG1670@2|Bacteria,1RKKE@1224|Proteobacteria,2UHTI@28211|Alphaproteobacteria,2JXVF@204441|Rhodospirillales 204441|Rhodospirillales J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 TGS3_k127_6205834_4 1320556.AVBP01000002_gene4171 2.518e-39 151.0 2DTSP@1|root,33MH6@2|Bacteria,1NNPD@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - TGS3_k127_6218456_1 1280949.HAD_01800 8.96e-64 224.0 COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2U5CW@28211|Alphaproteobacteria,43XG7@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Acetolactate synthase ilvH - 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT,ACT_5,ALS_ss_C TGS3_k127_6218456_0 1161401.ASJA01000022_gene135 9.635e-180 577.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSCJ@28211|Alphaproteobacteria,43WRC@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer TGS3_k127_6218456_2 357808.RoseRS_1962 3.844e-16 78.0 COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi,3753Z@32061|Chloroflexia 32061|Chloroflexia E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 TGS3_k127_6238855_0 1247963.JPHU01000003_gene1272 0.0 1234.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2TS7S@28211|Alphaproteobacteria 28211|Alphaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 TGS3_k127_6238855_3 195105.CN97_11250 3.003e-48 175.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N TGS3_k127_6238855_2 272943.RSP_1701 1.395e-51 190.0 COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,2U592@28211|Alphaproteobacteria,1FBMF@1060|Rhodobacter 28211|Alphaproteobacteria J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 TGS3_k127_631777_3 1247963.JPHU01000001_gene2028 1.4e-68 237.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2U5JU@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N TGS3_k127_631777_6 1161401.ASJA01000018_gene1226 1.738e-25 106.0 COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2UF4D@28211|Alphaproteobacteria,43YEG@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Belongs to the bacterial ribosomal protein bL33 family rpmG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 TGS3_k127_631777_0 402881.Plav_2815 2.601e-158 511.0 COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,1JNCR@119043|Rhodobiaceae 28211|Alphaproteobacteria T diguanylate cyclase pleD GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 ko:K02488 ko02020,ko04112,map02020,map04112 M00511 R08057 - ko00000,ko00001,ko00002,ko01000,ko02022 - - - GGDEF,Response_reg TGS3_k127_631777_5 663610.JQKO01000001_gene816 3.641e-49 179.0 COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2U745@28211|Alphaproteobacteria,3NB2Y@45404|Beijerinckiaceae 28211|Alphaproteobacteria T cheY-homologous receiver domain - - - ko:K11443 ko02020,ko04112,map02020,map04112 M00511 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg TGS3_k127_631777_2 991905.SL003B_1838 4.155e-135 443.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2TSJN@28211|Alphaproteobacteria,4BPS5@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C TGS3_k127_631777_4 1123503.KB908061_gene637 4.661e-55 196.0 COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2U9H4@28211|Alphaproteobacteria,2KG98@204458|Caulobacterales 204458|Caulobacterales J Endoribonuclease - - - - - - - - - - - - YjgF_endoribonc TGS3_k127_631777_1 935565.JAEM01000001_gene460 3.516e-140 456.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2TS5I@28211|Alphaproteobacteria,2PV8S@265|Paracoccus 28211|Alphaproteobacteria S Peptidogalycan biosysnthesis/recognition MA20_36195 - - ko:K09919 - - - - ko00000 - - - FemAB_like TGS3_k127_6331704_0 1207058.L53_00330 3.495e-307 976.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2TSAE@28211|Alphaproteobacteria,43WFC@69657|Hyphomonadaceae 28211|Alphaproteobacteria S COG2373 Large extracellular alpha-helical protein MA20_30110 - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,MG1,PAN_1,Thiol-ester_cl TGS3_k127_6338873_1 517722.AEUE01000010_gene548 5.829e-141 455.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,2K1FE@204457|Sphingomonadales 204457|Sphingomonadales CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh TGS3_k127_6338873_3 517722.AEUE01000010_gene549 2.735e-75 260.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2TRRS@28211|Alphaproteobacteria,2JZWQ@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C TGS3_k127_6338873_0 517722.AEUE01000010_gene550 2.866e-232 727.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TR6K@28211|Alphaproteobacteria,2K0IM@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase TGS3_k127_6338873_2 1161401.ASJA01000022_gene134 3.538e-138 445.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TR1H@28211|Alphaproteobacteria,43WHR@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 TGS3_k127_6344898_6 1122137.AQXF01000004_gene1811 2.535e-09 59.0 COG3595@1|root,COG3595@2|Bacteria,1N8NB@1224|Proteobacteria,2TZMI@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 TGS3_k127_6344898_5 1121948.AUAC01000002_gene1933 1.477e-36 149.0 COG1983@1|root,COG1983@2|Bacteria 2|Bacteria KT positive regulation of macromolecule biosynthetic process - - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - DUF2807,PspC TGS3_k127_6344898_4 1177928.TH2_08721 5.15e-50 183.0 COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2U7H5@28211|Alphaproteobacteria,2JTP4@204441|Rhodospirillales 204441|Rhodospirillales M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - - - - - - - - - - Fasciclin TGS3_k127_6344898_0 414684.RC1_3285 2.043e-118 392.0 COG0577@1|root,COG0577@2|Bacteria,1MX7X@1224|Proteobacteria,2TTIP@28211|Alphaproteobacteria 28211|Alphaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD TGS3_k127_6344898_1 1429916.X566_23275 2.67e-108 364.0 COG0577@1|root,COG0577@2|Bacteria,1MWBK@1224|Proteobacteria,2TUJD@28211|Alphaproteobacteria,3JWCP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD TGS3_k127_6344898_2 394221.Mmar10_0819 2.1e-104 343.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VEU2@28211|Alphaproteobacteria,43XPP@69657|Hyphomonadaceae 28211|Alphaproteobacteria V ABC transporter - - - ko:K02003,ko:K05685 ko02010,map02010 M00258,M00709 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 - - ABC_tran TGS3_k127_6344898_3 414684.RC1_3282 8.038e-76 268.0 COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,2U0VF@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_3,HlyD_D23 TGS3_k127_6367953_0 566466.NOR53_1151 7.123e-201 636.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,1J4P5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcSMS35_1347.EcSMS35_4486 PGI TGS3_k127_6367953_2 1397528.Q671_00415 2.83e-47 179.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria,1XK9Y@135619|Oceanospirillales 135619|Oceanospirillales M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03767 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase TGS3_k127_6367953_1 1247963.JPHU01000007_gene1603 1.07e-126 412.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2TSTH@28211|Alphaproteobacteria 28211|Alphaproteobacteria J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His TGS3_k127_639489_0 1122137.AQXF01000001_gene2504 1.367e-258 806.0 COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2TQNJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysC - 2.7.1.25,2.7.7.4 ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,GTP_EFTU,GTP_EFTU_D2 TGS3_k127_639489_2 394221.Mmar10_2636 2.03e-44 185.0 COG2114@1|root,COG2114@2|Bacteria,1R86S@1224|Proteobacteria,2U57P@28211|Alphaproteobacteria,43XWJ@69657|Hyphomonadaceae 28211|Alphaproteobacteria T Pfam Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - DUF4071,Guanylate_cyc TGS3_k127_639489_1 509190.Cseg_0581 5.939e-101 338.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2KG83@204458|Caulobacterales 204458|Caulobacterales C belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh TGS3_k127_6407712_0 1122132.AQYH01000002_gene1275 1.231e-103 346.0 COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,2TS4S@28211|Alphaproteobacteria,4B9AE@82115|Rhizobiaceae 28211|Alphaproteobacteria S protein conserved in bacteria ymdB GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - ko:K09769 - - - - ko00000 - - - YmdB TGS3_k127_6407712_1 1217720.ALOX01000006_gene1662 1.685e-42 164.0 COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2UBY4@28211|Alphaproteobacteria,2JTJ1@204441|Rhodospirillales 204441|Rhodospirillales H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig TGS3_k127_6407712_2 1470591.BW41_01827 3.473e-26 122.0 28JZK@1|root,2Z9PJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - TGS3_k127_6423623_0 314254.OA2633_05361 7.542e-233 737.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2TRHK@28211|Alphaproteobacteria,43WUI@69657|Hyphomonadaceae 28211|Alphaproteobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2 TGS3_k127_6445998_1 1292034.OR37_03142 6.827e-35 145.0 COG0412@1|root,COG0412@2|Bacteria,1R5J6@1224|Proteobacteria,2UE6V@28211|Alphaproteobacteria,2KGXF@204458|Caulobacterales 204458|Caulobacterales Q dienelactone hydrolase - - - - - - - - - - - - DLH,Peptidase_S9 TGS3_k127_6445998_0 1382303.JPOM01000001_gene2269 3.554e-101 340.0 COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,2KG1B@204458|Caulobacterales 204458|Caulobacterales G PFAM PfkB domain protein - - - - - - - - - - - - PfkB TGS3_k127_6453059_2 1174684.EBMC1_00115 2.467e-20 96.0 COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,2TREF@28211|Alphaproteobacteria,2K0MB@204457|Sphingomonadales 204457|Sphingomonadales E arginine N-succinyltransferase astA - 2.3.1.109 ko:K00673 ko00330,ko01100,map00330,map01100 - R00832 RC00004,RC00064 ko00000,ko00001,ko01000 - - - AstA TGS3_k127_6453059_0 1161401.ASJA01000008_gene1583 2.361e-128 422.0 COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2TRTW@28211|Alphaproteobacteria,43WPY@69657|Hyphomonadaceae 28211|Alphaproteobacteria E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases MA20_32325 - 3.4.17.11 ko:K01295 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 TGS3_k127_6453059_1 1238182.C882_3937 1.798e-125 435.0 COG0841@1|root,COG0841@2|Bacteria,1R2RN@1224|Proteobacteria,2TZQG@28211|Alphaproteobacteria,2JZ4G@204441|Rhodospirillales 204441|Rhodospirillales V MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL TGS3_k127_6456356_0 1380380.JIAX01000006_gene785 2.447e-194 613.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2TR4P@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N TGS3_k127_6456356_2 1247963.JPHU01000002_gene2681 1.078e-43 164.0 COG1396@1|root,COG1396@2|Bacteria,1RDBW@1224|Proteobacteria,2U7CY@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator MA20_23890 - - - - - - - - - - - HTH_3 TGS3_k127_6456356_1 1247963.JPHU01000002_gene2682 1.243e-66 233.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2TQRC@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase TGS3_k127_6479875_1 685035.ADAE01000007_gene1297 1.908e-258 807.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,2TRTQ@28211|Alphaproteobacteria,2K026@204457|Sphingomonadales 204457|Sphingomonadales EG Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD TGS3_k127_6479875_2 1123270.ATUR01000005_gene563 1.713e-169 539.0 COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2TRXI@28211|Alphaproteobacteria,2JZWR@204457|Sphingomonadales 204457|Sphingomonadales EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN TGS3_k127_6479875_0 266779.Meso_1488 2.568e-271 853.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TR1I@28211|Alphaproteobacteria,43HBD@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E acetolactate synthase ilvI - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N TGS3_k127_6479875_3 1121028.ARQE01000004_gene1241 6.242e-38 147.0 COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2U5CW@28211|Alphaproteobacteria,2PJNB@255475|Aurantimonadaceae 28211|Alphaproteobacteria E ACT domain ilvH - 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT,ACT_5,ALS_ss_C TGS3_k127_6506248_0 402881.Plav_1751 3.103e-212 668.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,1JN2K@119043|Rhodobiaceae 28211|Alphaproteobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N TGS3_k127_6506248_1 1380380.JIAX01000006_gene1001 1.44e-82 277.0 COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2TRI7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S A circularly permuted ATPgrasp MA20_32420 - - - - - - - - - - - CP_ATPgrasp_2 TGS3_k127_6524625_0 1247963.JPHU01000016_gene1039 3.746e-123 401.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N TGS3_k127_6524625_4 1247963.JPHU01000001_gene2046 1.501e-26 119.0 2DPWJ@1|root,333PH@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - TGS3_k127_6524625_2 1247963.JPHU01000001_gene2047 1.223e-46 171.0 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria 28211|Alphaproteobacteria U biopolymer transport protein tolR - - ko:K03559,ko:K03560 - - - - ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 - - ExbD TGS3_k127_6524625_1 1247963.JPHU01000001_gene2048 2.171e-85 288.0 COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2TQXQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria U MotA TolQ ExbB proton channel tolQ GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB TGS3_k127_6524625_3 1247963.JPHU01000003_gene1222 2.188e-44 164.0 COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2UBYM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S thioesterase' ybgC - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT TGS3_k127_6534377_1 1517416.IDAT_01225 7.939e-81 284.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,2QF81@267893|Idiomarinaceae 1236|Gammaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,His_kinase TGS3_k127_6534377_0 1122137.AQXF01000003_gene1873 5.481e-99 330.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2TSPC@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg TGS3_k127_6534377_2 1161401.ASJA01000005_gene2468 2.116e-09 66.0 COG1680@1|root,COG1680@2|Bacteria,1PQ2Z@1224|Proteobacteria,2U1GN@28211|Alphaproteobacteria,43X4A@69657|Hyphomonadaceae 28211|Alphaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase TGS3_k127_6554066_7 1122218.KB893654_gene2143 6.587e-42 166.0 COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2U78E@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Protein of unknown function (DUF3485) epsI - - - - - - - - - - - DUF3485,Exosortase_EpsH TGS3_k127_6554066_1 1158165.KB898881_gene688 2.689e-174 571.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales 135613|Chromatiales E Asparagine synthase, glutamine-hydrolyzing - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 TGS3_k127_6554066_9 1121861.KB899948_gene2443 1.367e-29 131.0 COG5653@1|root,COG5653@2|Bacteria,1RINE@1224|Proteobacteria,2U8NS@28211|Alphaproteobacteria,2JVVD@204441|Rhodospirillales 204441|Rhodospirillales M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 TGS3_k127_6554066_5 1380394.JADL01000008_gene3673 1.773e-72 258.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2U43G@28211|Alphaproteobacteria,2JQ88@204441|Rhodospirillales 204441|Rhodospirillales M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 TGS3_k127_6554066_3 1247963.JPHU01000005_gene272 5.601e-169 539.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRSS@28211|Alphaproteobacteria 28211|Alphaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh TGS3_k127_6554066_13 314260.PB2503_12019 7.25e-07 55.0 COG2919@1|root,COG2919@2|Bacteria 2|Bacteria D cell cycle MA20_41765 - - - - - - - - - - - DivIC TGS3_k127_6554066_0 1131814.JAFO01000001_gene2696 1.323e-206 650.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria,3EY81@335928|Xanthobacteraceae 28211|Alphaproteobacteria F Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N TGS3_k127_6554066_4 926554.KI912680_gene831 2.207e-132 446.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - ko:K17734 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S8 TGS3_k127_6554066_10 1121949.AQXT01000002_gene729 1.009e-24 106.0 COG0333@1|root,COG0333@2|Bacteria,1PU3Y@1224|Proteobacteria,2UF54@28211|Alphaproteobacteria,440MY@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p TGS3_k127_6554066_2 1245469.S58_05930 4.507e-173 563.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR15@28211|Alphaproteobacteria,3JQQB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain MA20_22975 - - ko:K11731 ko00281,map00281 - R08089 RC01893 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N TGS3_k127_6554066_11 247633.GP2143_13201 1.059e-24 115.0 COG1309@1|root,COG1309@2|Bacteria,1RAF9@1224|Proteobacteria,1S7FQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N TGS3_k127_6554066_6 883126.HMPREF9710_00883 6.489e-49 180.0 COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,2VQS2@28216|Betaproteobacteria,477AJ@75682|Oxalobacteraceae 28216|Betaproteobacteria Q Thioesterase superfamily - - - - - - - - - - - - 4HBT TGS3_k127_6554066_8 1280953.HOC_00765 6.602e-30 128.0 COG0739@1|root,COG0739@2|Bacteria,1Q5IC@1224|Proteobacteria,2V6QH@28211|Alphaproteobacteria,43XYN@69657|Hyphomonadaceae 28211|Alphaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - Peptidase_M23 TGS3_k127_6561868_4 244582.JQAK01000001_gene1683 1.247e-59 215.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,47EYH@766|Rickettsiales 766|Rickettsiales E Glutamine amidotransferase domain - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 TGS3_k127_6561868_0 941449.dsx2_1083 3.668e-274 857.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2M88F@213115|Desulfovibrionales 28221|Deltaproteobacteria E TIGRFAM asparagine synthase (glutamine-hydrolyzing) asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 TGS3_k127_6561868_1 1479238.JQMZ01000001_gene2146 1.77e-124 410.0 COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,2TTGZ@28211|Alphaproteobacteria,43WFA@69657|Hyphomonadaceae 28211|Alphaproteobacteria M UDP-N-acetylglucosamine 2-epimerase wecB - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 TGS3_k127_6561868_5 941449.dsx2_1081 7.898e-46 185.0 COG2192@1|root,COG2227@1|root,COG2192@2|Bacteria,COG2227@2|Bacteria,1MWBA@1224|Proteobacteria,42N15@68525|delta/epsilon subdivisions,2WJ0Y@28221|Deltaproteobacteria,2M82I@213115|Desulfovibrionales 28221|Deltaproteobacteria O PFAM Carbamoyltransferase - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N TGS3_k127_6561868_3 941449.dsx2_1080 4.649e-93 330.0 COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,42NNW@68525|delta/epsilon subdivisions,2WMWA@28221|Deltaproteobacteria,2MA46@213115|Desulfovibrionales 28221|Deltaproteobacteria GM pfam abc - - - ko:K09691 ko02010,map02010 M00250 - - ko00000,ko00001,ko00002,ko02000 3.A.1.103 - - ABC_tran,Wzt_C TGS3_k127_6561868_6 941449.dsx2_1082 4.033e-44 170.0 COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,42SZT@68525|delta/epsilon subdivisions,2WPXG@28221|Deltaproteobacteria,2M8D4@213115|Desulfovibrionales 28221|Deltaproteobacteria GM PFAM ABC-2 type transporter - - - ko:K09690 ko02010,map02010 M00250 - - ko00000,ko00001,ko00002,ko02000 3.A.1.103 - - ABC2_membrane TGS3_k127_6561868_2 330214.NIDE3009 2.606e-95 338.0 COG5360@1|root,COG5360@2|Bacteria 2|Bacteria S Heparinase II/III-like protein - - - - - - - - - - - - Hepar_II_III,Hepar_II_III_N TGS3_k127_6561868_7 247490.KSU1_D0299 1.375e-25 112.0 COG0500@1|root,COG2226@2|Bacteria,2J1BW@203682|Planctomycetes 203682|Planctomycetes Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_25 TGS3_k127_6565758_7 1411123.JQNH01000001_gene105 3.681e-170 541.0 COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria 28211|Alphaproteobacteria C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding TGS3_k127_6565758_11 935863.AWZR01000001_gene1662 6.811e-26 115.0 2EKD9@1|root,33E3J@2|Bacteria,1RIMW@1224|Proteobacteria,1S7IQ@1236|Gammaproteobacteria,1XB6N@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - TGS3_k127_6565758_5 1123503.KB908056_gene1875 3.827e-213 672.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TRN7@28211|Alphaproteobacteria,2KG5Y@204458|Caulobacterales 204458|Caulobacterales C Dehydrogenase - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim TGS3_k127_6565758_12 765952.PUV_05530 2.707e-10 67.0 2EFVT@1|root,339N0@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - TGS3_k127_6565758_3 685778.AORL01000021_gene828 3.589e-225 709.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,2TRS3@28211|Alphaproteobacteria,2K1CG@204457|Sphingomonadales 204457|Sphingomonadales G Alpha-amylase domain - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Alpha-amylase,DUF3459 TGS3_k127_6565758_4 1247963.JPHU01000006_gene199 1.519e-216 688.0 COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,2U0DP@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Alpha amylase catalytic - - - - - - - - - - - - Alpha-amylase TGS3_k127_6565758_1 1044.EH31_05295 5.931e-279 874.0 COG1082@1|root,COG1082@2|Bacteria,1NNTS@1224|Proteobacteria,2U06E@28211|Alphaproteobacteria,2K1T2@204457|Sphingomonadales 204457|Sphingomonadales G Glycosyl-hydrolase 97 C-terminal, oligomerisation - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - GH97_C,GH97_N,Glyco_hydro_97 TGS3_k127_6565758_6 1123503.KB908056_gene1814 6.738e-201 636.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2TQXA@28211|Alphaproteobacteria,2KF16@204458|Caulobacterales 204458|Caulobacterales G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N TGS3_k127_6565758_10 394221.Mmar10_2641 4.192e-46 177.0 COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,2U77K@28211|Alphaproteobacteria,43XYX@69657|Hyphomonadaceae 28211|Alphaproteobacteria G COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase pgl - 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso TGS3_k127_6565758_2 394221.Mmar10_2640 1.71e-248 782.0 COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,2TQNS@28211|Alphaproteobacteria,43WR0@69657|Hyphomonadaceae 28211|Alphaproteobacteria EG Belongs to the IlvD Edd family edd - 4.2.1.12 ko:K01690 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00008 R02036 RC00543 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD TGS3_k127_6565758_8 394221.Mmar10_2672 3.238e-73 260.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2U0CA@28211|Alphaproteobacteria,43XW8@69657|Hyphomonadaceae 28211|Alphaproteobacteria G Glucokinase glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase,Glyco_hydro_1 TGS3_k127_6565758_9 394221.Mmar10_2671 1.611e-66 232.0 COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,2TUMH@28211|Alphaproteobacteria,43XRN@69657|Hyphomonadaceae 28211|Alphaproteobacteria G COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase eda GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase TGS3_k127_6565758_0 1247963.JPHU01000006_gene198 1.184e-280 891.0 COG1629@1|root,COG1629@2|Bacteria,1MWTT@1224|Proteobacteria,2TURM@28211|Alphaproteobacteria 28211|Alphaproteobacteria P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - OMP_b-brl_3,Plug,TonB_dep_Rec TGS3_k127_6588393_1 1500890.JQNL01000001_gene843 2.585e-37 143.0 COG1670@1|root,COG1670@2|Bacteria,1RD77@1224|Proteobacteria,1SZ7D@1236|Gammaproteobacteria,1X62B@135614|Xanthomonadales 135614|Xanthomonadales J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 TGS3_k127_6588393_0 253839.SSNG_00453 1.398e-128 426.0 COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria 201174|Actinobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family algD - 1.1.1.132 ko:K00066 ko00051,ko00520,ko02020,map00051,map00520,map02020 - R00880 RC00291 ko00000,ko00001,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N TGS3_k127_6588393_2 1247963.JPHU01000002_gene2664 3.085e-13 70.0 COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2TSV6@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Catalyzes the reversible oxidation of malate to oxaloacetate mdh GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N TGS3_k127_6605904_1 1479238.JQMZ01000001_gene1135 7.467e-83 281.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2TT6B@28211|Alphaproteobacteria,440PN@69657|Hyphomonadaceae 28211|Alphaproteobacteria P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD TGS3_k127_6605904_2 1267005.KB911255_gene2851 1.393e-53 203.0 COG1120@1|root,COG1120@2|Bacteria,1QPWJ@1224|Proteobacteria,2U1TK@28211|Alphaproteobacteria,3N9EA@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria HP ATPases associated with a variety of cellular activities - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran TGS3_k127_6605904_3 1125973.JNLC01000015_gene3401 7.322e-49 181.0 COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2U5J1@28211|Alphaproteobacteria,3JS3E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Cobalamin adenosyltransferase yvqK - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans TGS3_k127_6605904_0 551789.ATVJ01000001_gene2291 2.875e-284 883.0 COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,2U15C@28211|Alphaproteobacteria,43X18@69657|Hyphomonadaceae 28211|Alphaproteobacteria E COG3104 Dipeptide tripeptide permease - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 TGS3_k127_6612567_2 1230476.C207_02851 1.139e-17 87.0 COG0457@1|root,COG0457@2|Bacteria,1R8RA@1224|Proteobacteria,2UP7M@28211|Alphaproteobacteria,3K3NR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - TGS3_k127_6612567_0 1230476.C207_02851 9.434e-117 383.0 COG0457@1|root,COG0457@2|Bacteria,1R8RA@1224|Proteobacteria,2UP7M@28211|Alphaproteobacteria,3K3NR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - TGS3_k127_6612567_3 1294143.H681_12395 1.038e-09 68.0 COG0726@1|root,COG0726@2|Bacteria 2|Bacteria G polysaccharide deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 TGS3_k127_6612567_1 1545915.JROG01000001_gene358 5.858e-25 108.0 COG3744@1|root,COG3744@2|Bacteria,1N6G7@1224|Proteobacteria,2UEBD@28211|Alphaproteobacteria,2K6UG@204457|Sphingomonadales 204457|Sphingomonadales S PIN domain - - - - - - - - - - - - PIN TGS3_k127_6622792_1 1125973.JNLC01000013_gene4014 2.72e-106 351.0 COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,3JRK8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ KR domain MA20_18175 - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 TGS3_k127_6622792_5 1123059.KB823013_gene652 3.905e-18 91.0 COG3063@1|root,COG3063@2|Bacteria,1QVFJ@1224|Proteobacteria,2TWDP@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_2,TPR_8 TGS3_k127_6622792_2 1304878.AUGD01000010_gene4711 8.748e-95 321.0 COG0498@1|root,COG0498@2|Bacteria,1R7X1@1224|Proteobacteria,2TUR3@28211|Alphaproteobacteria,3JU0E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Pyridoxal-phosphate dependent enzyme MA20_41710 - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP TGS3_k127_6622792_4 420662.Mpe_A3500 5.977e-30 126.0 COG3759@1|root,COG3759@2|Bacteria,1MZ4F@1224|Proteobacteria,2VUPP@28216|Betaproteobacteria,1KMDF@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Protein of unknown function (DUF1304) - - - ko:K08987 - - - - ko00000 - - - DUF1304 TGS3_k127_6622792_3 1242864.D187_007620 7.129e-93 310.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42S9C@68525|delta/epsilon subdivisions,2WNRR@28221|Deltaproteobacteria,2Z051@29|Myxococcales 28221|Deltaproteobacteria Q Dienelactone hydrolase family - - - - - - - - - - - - DLH TGS3_k127_6622792_0 551789.ATVJ01000003_gene167 2.887e-195 619.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2TRFV@28211|Alphaproteobacteria,43W88@69657|Hyphomonadaceae 28211|Alphaproteobacteria G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C TGS3_k127_6642926_1 1247963.JPHU01000005_gene429 5.696e-108 389.0 COG3164@1|root,COG3164@2|Bacteria,1MVDY@1224|Proteobacteria,2TSGG@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Protein of unknown function MA20_30770 - - - - - - - - - - - AsmA_2,DUF3971 TGS3_k127_6642926_3 59538.XP_005975956.1 1.441e-65 227.0 COG1225@1|root,KOG0855@2759|Eukaryota,3A8UH@33154|Opisthokonta,3BXZK@33208|Metazoa,3DFA4@33213|Bilateria 33208|Metazoa O Peroxiredoxin Q, chloroplastic-like - - - - - - - - - - - - AhpC-TSA TGS3_k127_6642926_2 402881.Plav_3271 2.816e-71 250.0 COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,2TQJU@28211|Alphaproteobacteria,1JPSF@119043|Rhodobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF455) - - - - - - - - - - - - DUF455 TGS3_k127_6642926_0 1247963.JPHU01000005_gene431 6.992e-116 387.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases MA20_30780 - - - - - - - - - - - Peptidase_M23 TGS3_k127_6642926_4 1479238.JQMZ01000001_gene1983 1.966e-36 147.0 COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2U5DW@28211|Alphaproteobacteria,43Y3U@69657|Hyphomonadaceae 28211|Alphaproteobacteria M COG1664 Integral membrane protein CcmA involved in cell shape determination - - - - - - - - - - - - Bactofilin TGS3_k127_6665484_1 1247963.JPHU01000005_gene418 2.302e-79 279.0 COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,2U5H1@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Major facilitator superfamily - - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like TGS3_k127_6665484_0 1282361.ABAC402_16650 1.986e-97 325.0 COG2267@1|root,COG2267@2|Bacteria,1QUZX@1224|Proteobacteria,2TWE4@28211|Alphaproteobacteria,2KIJQ@204458|Caulobacterales 204458|Caulobacterales I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 TGS3_k127_6665484_3 1280954.HPO_05707 1.155e-44 177.0 COG3713@1|root,COG3713@2|Bacteria,1RF1U@1224|Proteobacteria,2U8SJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Outer membrane protein V - - - - - - - - - - - - MipA TGS3_k127_6665484_2 1282361.ABAC402_16640 2.317e-67 240.0 28PN6@1|root,2ZCB1@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4386) - - - - - - - - - - - - DUF4386 TGS3_k127_6665484_4 32057.KB217478_gene2650 5.047e-27 118.0 COG0662@1|root,COG0662@2|Bacteria,1GFZG@1117|Cyanobacteria 1117|Cyanobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 TGS3_k127_6666677_4 190650.CC_3693 6.748e-19 93.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2UAPV@28211|Alphaproteobacteria,2KIM2@204458|Caulobacterales 204458|Caulobacterales Q MlaC protein - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC TGS3_k127_6666677_3 1244869.H261_19998 6.053e-50 190.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2U7CZ@28211|Alphaproteobacteria,2JS21@204441|Rhodospirillales 204441|Rhodospirillales M MlaA lipoprotein - - - ko:K04754 - - - - ko00000 - - - MlaA TGS3_k127_6666677_2 1287116.X734_25955 1.228e-103 346.0 COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,2TSMV@28211|Alphaproteobacteria,43H1Z@69277|Phyllobacteriaceae 28211|Alphaproteobacteria KQ arsR family arsR - - - - - - - - - - - HTH_20,HTH_5,Methyltransf_11,Methyltransf_31 TGS3_k127_6666677_1 1247963.JPHU01000004_gene531 2.886e-134 432.0 COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2TQZA@28211|Alphaproteobacteria 28211|Alphaproteobacteria E reductase metF GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR TGS3_k127_6666677_0 402881.Plav_2403 1.662e-176 565.0 COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,1JN1H@119043|Rhodobiaceae 28211|Alphaproteobacteria E B12 binding domain metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans TGS3_k127_6690355_5 1121033.AUCF01000003_gene3158 1.351e-51 190.0 COG0625@1|root,COG0625@2|Bacteria,1MXM4@1224|Proteobacteria,2TTXD@28211|Alphaproteobacteria,2JRUQ@204441|Rhodospirillales 204441|Rhodospirillales O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_C_3,GST_N_3 TGS3_k127_6690355_1 935840.JAEQ01000011_gene1852 1.518e-153 499.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2TR5E@28211|Alphaproteobacteria,43GQ2@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 TGS3_k127_6690355_6 459495.SPLC1_S510180 2.391e-28 122.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - - - - - - - - - - Methyltransf_11,Methyltransf_12,Methyltransf_25 TGS3_k127_6690355_0 351016.RAZWK3B_01015 3.331e-196 650.0 COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,1R8SK@1224|Proteobacteria,2UNN5@28211|Alphaproteobacteria 28211|Alphaproteobacteria O G8 - - - - - - - - - - - - G8 TGS3_k127_6690355_3 1247963.JPHU01000008_gene2817 1.96e-110 363.0 COG3751@1|root,COG3751@2|Bacteria,1RJST@1224|Proteobacteria,2UAC0@28211|Alphaproteobacteria 28211|Alphaproteobacteria O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_3 TGS3_k127_6690355_2 1121479.AUBS01000012_gene1418 7.186e-112 374.0 COG1215@1|root,COG1215@2|Bacteria,1QUG1@1224|Proteobacteria,2TWJ1@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glyco_trans_2_3,Glycos_transf_2 TGS3_k127_6690355_4 745310.G432_05370 1.364e-68 248.0 COG1215@1|root,COG1215@2|Bacteria,1PU38@1224|Proteobacteria,2U5E7@28211|Alphaproteobacteria,2K3C5@204457|Sphingomonadales 204457|Sphingomonadales M Glycosyl transferase family group 2 - - - - - - - - - - - - Glyco_tranf_2_3 TGS3_k127_6690355_7 1121479.AUBS01000012_gene1408 1.437e-24 105.0 COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,2TUFG@28211|Alphaproteobacteria 28211|Alphaproteobacteria M glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 TGS3_k127_6706787_1 1247963.JPHU01000001_gene1993 4.352e-146 468.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2TQWA@28211|Alphaproteobacteria 28211|Alphaproteobacteria C heme copper-type cytochrome quinol oxidase, subunit 3 ctaE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 TGS3_k127_6706787_4 190650.CC_1846 3.403e-78 268.0 COG0500@1|root,COG2226@2|Bacteria,1MV7N@1224|Proteobacteria,2TVGZ@28211|Alphaproteobacteria,2KIBR@204458|Caulobacterales 204458|Caulobacterales Q Hypothetical methyltransferase - - - - - - - - - - - - Methyltransf_11 TGS3_k127_6706787_5 1247963.JPHU01000005_gene333 1.349e-67 237.0 COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,2U6ZT@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I ctaG GO:0008150,GO:0008535,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - ko:K02258 ko00190,ko01100,ko04714,map00190,map01100,map04714 M00154 - - ko00000,ko00001,ko00002,ko03029 3.D.4.8 - - CtaG_Cox11 TGS3_k127_6706787_2 266779.Meso_0743 1.686e-102 343.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2TRD8@28211|Alphaproteobacteria,43IFP@69277|Phyllobacteriaceae 28211|Alphaproteobacteria O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA TGS3_k127_6706787_0 1280941.HY2_10540 7.689e-287 889.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,43WAF@69657|Hyphomonadaceae 28211|Alphaproteobacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 TGS3_k127_6706787_3 1247963.JPHU01000005_gene337 5.868e-102 345.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,2TRK6@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM TGS3_k127_6706787_6 331869.BAL199_15563 7.264e-06 52.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2TRSR@28211|Alphaproteobacteria,4BP8B@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Putative modulator of DNA gyrase tldD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD TGS3_k127_6709162_6 32049.SYNPCC7002_A2717 7.691e-44 164.0 COG1741@1|root,COG1741@2|Bacteria,1G0UH@1117|Cyanobacteria,1GYC7@1129|Synechococcus 1117|Cyanobacteria S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin TGS3_k127_6709162_7 1120956.JHZK01000055_gene1850 7.696e-41 159.0 COG0822@1|root,COG0822@2|Bacteria,1RDGB@1224|Proteobacteria,2U74A@28211|Alphaproteobacteria,1JP2J@119043|Rhodobiaceae 28211|Alphaproteobacteria C NifU-like N terminal domain nifU - - - - - - - - - - - NifU_N TGS3_k127_6709162_2 1292034.OR37_02207 3.284e-116 381.0 COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2TSD9@28211|Alphaproteobacteria,2KG6K@204458|Caulobacterales 204458|Caulobacterales K Transcriptional regulator, LysR family - - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate TGS3_k127_6709162_1 314260.PB2503_04962 2.169e-139 459.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2TRJC@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase TGS3_k127_6709162_9 911045.PSE_1233 5.33e-10 64.0 COG0155@1|root,COG0155@2|Bacteria,1NGES@1224|Proteobacteria,2UFMV@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Protein of unknown function (DUF2849) - - - - - - - - - - - - DUF2849 TGS3_k127_6709162_4 509190.Cseg_1253 4.409e-77 267.0 COG0625@1|root,COG0625@2|Bacteria,1REDI@1224|Proteobacteria,2TUGP@28211|Alphaproteobacteria,2KGE3@204458|Caulobacterales 204458|Caulobacterales O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N TGS3_k127_6709162_0 1089552.KI911559_gene396 3.204e-243 762.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2TRCR@28211|Alphaproteobacteria,2JSH9@204441|Rhodospirillales 204441|Rhodospirillales C Sulfite reductase - - 1.8.1.2 ko:K00381 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr TGS3_k127_6709162_8 1038860.AXAP01000025_gene1659 5.392e-21 102.0 COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,2UDH7@28211|Alphaproteobacteria,3JY89@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF934) MA20_18215 - - - - - - - - - - - DUF934 TGS3_k127_6709162_3 1247963.JPHU01000011_gene711 8.87e-82 281.0 COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,2U5AP@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH Reduction of activated sulfate into sulfite cysH - 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - - DUF934,PAPS_reduct TGS3_k127_6709162_5 509190.Cseg_4123 5.177e-70 247.0 COG2267@1|root,COG2267@2|Bacteria,1NTH9@1224|Proteobacteria,2TWFW@28211|Alphaproteobacteria,2KG8W@204458|Caulobacterales 204458|Caulobacterales I PFAM alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 TGS3_k127_6718864_0 1112212.JH584235_gene2830 7.568e-88 293.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2TQNG@28211|Alphaproteobacteria,2K0Y3@204457|Sphingomonadales 204457|Sphingomonadales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N TGS3_k127_6718864_2 1120983.KB894570_gene1216 4.23e-47 181.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2TSKM@28211|Alphaproteobacteria,1JNZM@119043|Rhodobiaceae 28211|Alphaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N TGS3_k127_6718864_1 1134912.AJTV01000009_gene1920 1.705e-53 192.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2U70Z@28211|Alphaproteobacteria,36Y6K@31993|Methylocystaceae 28211|Alphaproteobacteria L Crossover junction endodeoxyribonuclease RuvC ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC TGS3_k127_6718864_3 504472.Slin_2777 1.784e-17 91.0 2C25Y@1|root,3399H@2|Bacteria,4NXDI@976|Bacteroidetes,47SDB@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - TGS3_k127_6718864_4 1122613.ATUP01000001_gene1434 2.25e-16 90.0 2CFVI@1|root,33SP5@2|Bacteria,1NU9W@1224|Proteobacteria,2UQT8@28211|Alphaproteobacteria,43Z7E@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_6719277_1 314260.PB2503_01507 3.441e-145 464.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 TGS3_k127_6719277_7 648757.Rvan_2854 4.874e-44 161.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2U9AQ@28211|Alphaproteobacteria,3N72T@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 TGS3_k127_6719277_4 1283300.ATXB01000001_gene658 1.792e-58 211.0 COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria,1XESY@135618|Methylococcales 135618|Methylococcales M Belongs to the ompA family - - - - - - - - - - - - Gly-zipper_Omp,OmpA TGS3_k127_6719277_5 1297865.APJD01000009_gene2833 1.56e-50 194.0 COG2200@1|root,COG2200@2|Bacteria,1MU4F@1224|Proteobacteria,2TU9M@28211|Alphaproteobacteria,3JRX2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Putative diguanylate phosphodiesterase MA20_05620 - - ko:K13593 ko04112,map04112 - - - ko00000,ko00001 - - - EAL TGS3_k127_6719277_2 1247963.JPHU01000001_gene1908 5.714e-95 318.0 COG0647@1|root,COG0647@2|Bacteria,1MU9Y@1224|Proteobacteria,2TUH0@28211|Alphaproteobacteria 28211|Alphaproteobacteria G sugar phosphatases of the HAD superfamily MA20_05625 - - - - - - - - - - - Hydrolase_6,Hydrolase_like TGS3_k127_6719277_3 1479238.JQMZ01000001_gene1256 3.564e-81 283.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2TTUY@28211|Alphaproteobacteria,43WNF@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase TGS3_k127_6719277_9 509190.Cseg_1586 2.468e-16 88.0 2E3UE@1|root,32YRS@2|Bacteria,1N75A@1224|Proteobacteria,2UCUH@28211|Alphaproteobacteria,2KIMW@204458|Caulobacterales 204458|Caulobacterales S Protein of unknown function (DUF2799) - - - - - - - - - - - - DUF2799 TGS3_k127_6719277_0 1247963.JPHU01000001_gene1911 0.0 1275.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2TR3N@28211|Alphaproteobacteria 28211|Alphaproteobacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS TGS3_k127_6719277_6 1247963.JPHU01000001_gene1912 5.447e-47 180.0 COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2UBUC@28211|Alphaproteobacteria 28211|Alphaproteobacteria MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 TGS3_k127_6719277_8 1247963.JPHU01000001_gene1913 3.826e-19 90.0 2C068@1|root,30N9J@2|Bacteria,1REH5@1224|Proteobacteria,2U74G@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3035) - - - - - - - - - - - - DUF3035 TGS3_k127_6733010_0 402881.Plav_3242 6.844e-120 395.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TTGJ@28211|Alphaproteobacteria,1JN9P@119043|Rhodobiaceae 28211|Alphaproteobacteria E Aminotransferase class I and II MA20_26420 - - - - - - - - - - - Aminotran_1_2 TGS3_k127_6733010_3 1122603.ATVI01000006_gene696 3.194e-66 233.0 2919Q@1|root,32EZ8@2|Bacteria,1R3DK@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - TGS3_k127_6733010_2 1282876.BAOK01000001_gene1342 8.269e-87 291.0 COG4312@1|root,COG4312@2|Bacteria 2|Bacteria S Bacterial protein of unknown function (DUF899) - - - - - - - - - - - - DUF899 TGS3_k127_6733010_1 1161401.ASJA01000013_gene711 6.802e-87 301.0 COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,2TV4M@28211|Alphaproteobacteria,43XTJ@69657|Hyphomonadaceae 28211|Alphaproteobacteria C glycerophosphoryl diester phosphodiesterase glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD TGS3_k127_6755535_6 1247963.JPHU01000012_gene851 4.048e-94 315.0 COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,2TSNX@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ short-chain dehydrogenase - - - - - - - - - - - - adh_short_C2 TGS3_k127_6755535_13 472175.EL18_03240 1.271e-25 114.0 COG5373@1|root,COG5373@2|Bacteria,1N7JV@1224|Proteobacteria,2TR7A@28211|Alphaproteobacteria,43K3N@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF4167) - - - - - - - - - - - - DUF4167 TGS3_k127_6755535_8 395964.KE386496_gene475 4.481e-60 219.0 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2TZFK@28211|Alphaproteobacteria,3NAAH@45404|Beijerinckiaceae 28211|Alphaproteobacteria J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_31 TGS3_k127_6755535_3 1247963.JPHU01000001_gene1941 1.038e-156 502.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2TQSV@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 TGS3_k127_6755535_10 1346791.M529_02400 1.126e-52 188.0 COG5611@1|root,COG5611@2|Bacteria,1N0FT@1224|Proteobacteria,2UCGC@28211|Alphaproteobacteria,2K75I@204457|Sphingomonadales 204457|Sphingomonadales K PIN domain - - - - - - - - - - - - PIN TGS3_k127_6755535_14 1336249.JADW01000004_gene3453 8.401e-21 96.0 COG2002@1|root,COG2002@2|Bacteria,1N3BE@1224|Proteobacteria,2UBXQ@28211|Alphaproteobacteria,4BG87@82115|Rhizobiaceae 28211|Alphaproteobacteria K SpoVT / AbrB like domain - - - - - - - - - - - - MazE_antitoxin TGS3_k127_6755535_1 1292034.OR37_02988 1.959e-189 598.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2TQSI@28211|Alphaproteobacteria,2KFD6@204458|Caulobacterales 204458|Caulobacterales I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG - 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE TGS3_k127_6755535_15 1415779.JOMH01000001_gene2431 8.691e-15 85.0 COG0810@1|root,COG0810@2|Bacteria,1R4VE@1224|Proteobacteria,1RN5E@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG0810 Periplasmic protein TonB, links inner and outer membranes - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C TGS3_k127_6755535_16 573065.Astex_0909 3.602e-10 70.0 COG1426@1|root,COG1426@2|Bacteria,1MYWX@1224|Proteobacteria,2U8C2@28211|Alphaproteobacteria,2KGH6@204458|Caulobacterales 204458|Caulobacterales S Helix-turn-helix domain - - - - - - - - - - - - HTH_25 TGS3_k127_6755535_0 1382303.JPOM01000001_gene308 8.25e-212 681.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,2TR3Z@28211|Alphaproteobacteria,2KF7C@204458|Caulobacterales 204458|Caulobacterales T Belongs to the PEP-utilizing enzyme family - - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C TGS3_k127_6755535_2 1382303.JPOM01000001_gene2434 2.57e-162 525.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2TRFA@28211|Alphaproteobacteria,2KFIQ@204458|Caulobacterales 204458|Caulobacterales E Belongs to the aspartokinase family - - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 TGS3_k127_6755535_5 1247963.JPHU01000004_gene611 3.62e-106 350.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2TRIK@28211|Alphaproteobacteria 28211|Alphaproteobacteria H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23 TGS3_k127_6755535_4 551789.ATVJ01000002_gene3144 3.209e-147 492.0 COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TVQR@28211|Alphaproteobacteria,43WZP@69657|Hyphomonadaceae 28211|Alphaproteobacteria T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - ko:K07001 - - - - ko00000 - - - Patatin,cNMP_binding TGS3_k127_6755535_11 314260.PB2503_12889 2.022e-40 154.0 COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2UBTA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria MA20_39715 - - - - - - - - - - - DUF1178 TGS3_k127_6755535_7 402881.Plav_1738 2.472e-93 316.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2TRGZ@28211|Alphaproteobacteria,1JN4U@119043|Rhodobiaceae 28211|Alphaproteobacteria S Carbon-nitrogen hydrolase MA20_39720 - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase TGS3_k127_6755535_12 1320556.AVBP01000023_gene2274 5.384e-30 120.0 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2UFM1@28211|Alphaproteobacteria,43KQU@69277|Phyllobacteriaceae 28211|Alphaproteobacteria O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins grxC GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0033218,GO:0042277,GO:0043167,GO:0043168,GO:0043295,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0055114,GO:0072341,GO:1900750,GO:1901681 - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin TGS3_k127_6755535_9 414684.RC1_2661 6.734e-59 213.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,2JSB6@204441|Rhodospirillales 204441|Rhodospirillales S Phosphoribosyl transferase domain - - - - - - - - - - - - Pribosyltran TGS3_k127_6755535_17 1333998.M2A_1839 5.756e-06 52.0 COG4961@1|root,COG4961@2|Bacteria,1MWXU@1224|Proteobacteria,2TRQP@28211|Alphaproteobacteria,4BQFA@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad,VWA TGS3_k127_6758709_0 314260.PB2503_01697 1.761e-297 921.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2TQPV@28211|Alphaproteobacteria 28211|Alphaproteobacteria J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 TGS3_k127_6758709_2 1247963.JPHU01000003_gene1485 3.939e-74 255.0 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,2U71H@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin TGS3_k127_6758709_1 366602.Caul_4087 7.638e-100 335.0 COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,2TTX5@28211|Alphaproteobacteria,2KHMH@204458|Caulobacterales 204458|Caulobacterales G PFAM major facilitator superfamily MFS_1 - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 TGS3_k127_6764785_1 1282876.BAOK01000001_gene3273 5.996e-120 391.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,4BRKU@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C FMN-dependent dehydrogenase lldD1 GO:0002218,GO:0002253,GO:0002376,GO:0002682,GO:0002684,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006950,GO:0006952,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0010204,GO:0016999,GO:0017000,GO:0017144,GO:0023052,GO:0031347,GO:0031349,GO:0042579,GO:0042742,GO:0042743,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0045088,GO:0045089,GO:0048518,GO:0048583,GO:0048584,GO:0050665,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0072593,GO:0080134,GO:0098542,GO:1903409 1.1.2.3 ko:K00101 ko00620,ko01100,map00620,map01100 - R00196 RC00044 ko00000,ko00001,ko01000 - - - FMN_dh TGS3_k127_6764785_0 1234595.C725_2386 2.267e-264 847.0 COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria 28211|Alphaproteobacteria P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec TGS3_k127_6764785_3 1122137.AQXF01000004_gene1739 7.814e-31 130.0 COG1595@1|root,COG1595@2|Bacteria,1N6SV@1224|Proteobacteria,2UJ82@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 TGS3_k127_6764785_2 1122137.AQXF01000004_gene1740 1.297e-37 155.0 COG3712@1|root,COG3712@2|Bacteria,1MZCK@1224|Proteobacteria,2UD4P@28211|Alphaproteobacteria 28211|Alphaproteobacteria PT Sigma factor regulatory protein FecR PupR family - - - ko:K07165 - - - - ko00000 - - - DUF4880,DUF4974,FecR TGS3_k127_6764785_4 1121948.AUAC01000002_gene1565 7.776e-23 112.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria,43WD4@69657|Hyphomonadaceae 28211|Alphaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec TGS3_k127_6774476_0 1161401.ASJA01000016_gene1351 2.857e-176 573.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TW3C@28211|Alphaproteobacteria,43WYR@69657|Hyphomonadaceae 28211|Alphaproteobacteria IQ AMP binding protein - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C_2,Acyltransferase,PP-binding TGS3_k127_6774476_1 1161401.ASJA01000016_gene1352 5.294e-30 130.0 COG0702@1|root,COG0702@2|Bacteria,1RCCP@1224|Proteobacteria,2TU1D@28211|Alphaproteobacteria,4415T@69657|Hyphomonadaceae 28211|Alphaproteobacteria GM NmrA-like family - - - - - - - - - - - - Epimerase,NAD_binding_10 TGS3_k127_6785313_0 1247963.JPHU01000005_gene268 4.228e-165 529.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2TQKJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f TGS3_k127_6785313_4 1197906.CAJQ02000003_gene3160 2.404e-21 107.0 COG3409@1|root,COG3409@2|Bacteria,1QSDM@1224|Proteobacteria,2U4B9@28211|Alphaproteobacteria,3JU8K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M PAN domain - - - - - - - - - - - - PAN_4 TGS3_k127_6785313_5 69395.JQLZ01000003_gene322 3.268e-08 63.0 COG2050@1|root,COG2050@2|Bacteria,1QEUC@1224|Proteobacteria,2V8JQ@28211|Alphaproteobacteria,2KIV5@204458|Caulobacterales 204458|Caulobacterales Q Thioesterase-like superfamily - - - - - - - - - - - - 4HBT TGS3_k127_6785313_3 1380391.JIAS01000015_gene259 4.484e-30 129.0 COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria,2UGR1@28211|Alphaproteobacteria,2JTVJ@204441|Rhodospirillales 204441|Rhodospirillales S Iron-binding zinc finger CDGSH type - - - - - - - - - - - - zf-CDGSH TGS3_k127_6785313_1 1280954.HPO_04155 2.584e-80 277.0 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2U0NP@28211|Alphaproteobacteria,43W9C@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA - 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly TGS3_k127_6785313_2 1282876.BAOK01000001_gene3020 2.953e-40 155.0 COG3791@1|root,COG3791@2|Bacteria,1N0W7@1224|Proteobacteria,2UEZQ@28211|Alphaproteobacteria,4BSS9@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA TGS3_k127_6790105_10 1380394.JADL01000002_gene1129 9.822e-05 47.0 2DSFG@1|root,33FYD@2|Bacteria 2|Bacteria S Heme exporter protein D (CcmD) - - - - - - - - - - - - CcmD TGS3_k127_6790105_8 1123060.JONP01000014_gene4188 1.617e-39 156.0 COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2TVBT@28211|Alphaproteobacteria,2JRQJ@204441|Rhodospirillales 204441|Rhodospirillales O once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system ccmA - 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - - ABC_tran TGS3_k127_6790105_6 1122929.KB908218_gene1680 1.412e-51 190.0 COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2TUSG@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB TGS3_k127_6790105_1 991905.SL003B_0250 1.092e-95 318.0 COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2TSW8@28211|Alphaproteobacteria,4BPH8@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmC GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - Cytochrom_C_asm TGS3_k127_6790105_7 441620.Mpop_1402 1.112e-39 152.0 COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2U99J@28211|Alphaproteobacteria,1JTMD@119045|Methylobacteriaceae 28211|Alphaproteobacteria O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH ccmE GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - ko:K02197 - - - - ko00000 - - - CcmE TGS3_k127_6790105_0 1247963.JPHU01000007_gene1624 6.663e-101 342.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2TSEA@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB TGS3_k127_6790105_3 1247963.JPHU01000007_gene1623 1.689e-91 309.0 COG3494@1|root,COG3494@2|Bacteria,1MWTH@1224|Proteobacteria,2U5B7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1009) cdsA2 - - ko:K09949 - - - - ko00000 - - - DUF1009 TGS3_k127_6790105_2 573065.Astex_2855 7.073e-92 309.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2TRK9@28211|Alphaproteobacteria,2KFFI@204458|Caulobacterales 204458|Caulobacterales M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep TGS3_k127_6790105_5 1247963.JPHU01000007_gene1621 5.346e-58 207.0 COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2U7G4@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA TGS3_k127_6790105_4 1247963.JPHU01000007_gene1620 1.001e-83 288.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2TS8U@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD TGS3_k127_6790105_9 402881.Plav_3187 1.696e-10 69.0 COG2825@1|root,COG2825@2|Bacteria,1NNT2@1224|Proteobacteria,2UM5J@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Outer membrane protein (OmpH-like) - - - - - - - - - - - - OmpH TGS3_k127_6808697_22 1007104.SUS17_1740 3.822e-14 78.0 COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TRAP@28211|Alphaproteobacteria,2K0IY@204457|Sphingomonadales 204457|Sphingomonadales EGP Major Facilitator - - - - - - - - - - - - Sugar_tr TGS3_k127_6808697_12 1247963.JPHU01000025_gene1546 2.485e-68 237.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2U5GR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily yrdA - - - - - - - - - - - Hexapep TGS3_k127_6808697_14 1121939.L861_24215 4.467e-61 217.0 COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,1S2I8@1236|Gammaproteobacteria,1XJ5Z@135619|Oceanospirillales 135619|Oceanospirillales O Maleylacetoacetate isomerase - - 5.2.1.4 ko:K01801 ko00350,ko01100,ko01120,map00350,map01100,map01120 - R03868 RC00867 ko00000,ko00001,ko01000 - - - GST_C_2,GST_C_3,GST_N,GST_N_3 TGS3_k127_6808697_3 1382303.JPOM01000001_gene2443 1.783e-173 549.0 COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,2TRCC@28211|Alphaproteobacteria,2KFJU@204458|Caulobacterales 204458|Caulobacterales C 4-hydroxyphenylpyruvate dioxygenase - - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Glyoxalase,Glyoxalase_5 TGS3_k127_6808697_20 1384054.N790_11550 7.121e-22 100.0 COG1846@1|root,COG1846@2|Bacteria,1N1CJ@1224|Proteobacteria,1SCUJ@1236|Gammaproteobacteria,1X6IP@135614|Xanthomonadales 135614|Xanthomonadales K MarR family transcriptional regulator - - - - - - - - - - - - MarR_2 TGS3_k127_6808697_13 1282876.BAOK01000001_gene2496 1.371e-64 234.0 COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,2TV6U@28211|Alphaproteobacteria,4BS3R@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria I Alpha/beta hydrolase family - - - - - - - - - - - - Hydrolase_4 TGS3_k127_6808697_18 1187851.A33M_2475 1.421e-22 101.0 COG1324@1|root,COG1324@2|Bacteria,1Q6BZ@1224|Proteobacteria,2VCHQ@28211|Alphaproteobacteria,3FEJZ@34008|Rhodovulum 28211|Alphaproteobacteria P CutA1 divalent ion tolerance protein - - - ko:K03926 - - - - ko00000 - - - CutA1 TGS3_k127_6808697_8 123899.JPQP01000020_gene1888 1.048e-91 307.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,3T2YJ@506|Alcaligenaceae 28216|Betaproteobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC TGS3_k127_6808697_7 1479238.JQMZ01000001_gene1142 1.398e-98 325.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria,43WAY@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM TGS3_k127_6808697_21 1247963.JPHU01000006_gene127 1.386e-17 91.0 2CDZX@1|root,3428F@2|Bacteria,1NXH2@1224|Proteobacteria,2UT5A@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_6808697_1 1247963.JPHU01000006_gene128 1.632e-184 599.0 COG5426@1|root,COG5426@2|Bacteria,1MVWA@1224|Proteobacteria,2TQNQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S membrane MA20_44660 - - - - - - - - - - - GATase1_like TGS3_k127_6808697_0 1247963.JPHU01000006_gene129 1.508e-203 664.0 28H8H@1|root,2Z7KE@2|Bacteria,1MV77@1224|Proteobacteria,2TSVV@28211|Alphaproteobacteria 28211|Alphaproteobacteria S N-terminal double-transmembrane domain MA20_44655 - - - - - - - - - - - BatA,DUF4159 TGS3_k127_6808697_11 1333998.M2A_2427 1.174e-69 246.0 COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,2TTDX@28211|Alphaproteobacteria,4BQ8T@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function DUF58 MA20_44650 - - - - - - - - - - - DUF58 TGS3_k127_6808697_6 402881.Plav_2234 6.055e-129 419.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2TR0T@28211|Alphaproteobacteria,1JN4I@119043|Rhodobiaceae 28211|Alphaproteobacteria S ATPase family associated with various cellular activities (AAA) moxR GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 TGS3_k127_6808697_2 1247963.JPHU01000006_gene132 4.551e-178 578.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2TSXA@28211|Alphaproteobacteria 28211|Alphaproteobacteria OU Signal peptide peptidase sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 TGS3_k127_6808697_16 114615.BRADO1965 1.912e-53 195.0 COG3816@1|root,COG3816@2|Bacteria,1RD5Q@1224|Proteobacteria,2U7DA@28211|Alphaproteobacteria,3JSDP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1285) MA20_44640 - - ko:K09986 - - - - ko00000 - - - DUF1285 TGS3_k127_6808697_17 1247963.JPHU01000006_gene134 1.229e-49 184.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2TV3Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes MA20_44635 - - - - - - - - - - - NUDIX TGS3_k127_6808697_9 1247963.JPHU01000006_gene135 1.75e-87 303.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2TRPZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria J tRNA nucleotidyltransferase poly(A) polymerase pcnB - 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd TGS3_k127_6808697_15 1292034.OR37_00730 1.29e-57 216.0 COG2304@1|root,COG4961@1|root,COG2304@2|Bacteria,COG4961@2|Bacteria,1MWXU@1224|Proteobacteria,2TRQP@28211|Alphaproteobacteria,2KHGU@204458|Caulobacterales 204458|Caulobacterales U Von Willebrand factor - - - - - - - - - - - - Tad,VWA TGS3_k127_6808697_4 314260.PB2503_09029 3.08e-141 450.0 COG0745@1|root,COG0745@2|Bacteria,1MWVI@1224|Proteobacteria,2TRSP@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain ctrA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02483,ko:K13584 ko02020,ko04112,map02020,map04112 M00512 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C TGS3_k127_6808697_5 1038860.AXAP01000003_gene8174 3.42e-141 462.0 COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,2TRXU@28211|Alphaproteobacteria,3JT0Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria NU ATP synthase alpha/beta family, nucleotide-binding domain fliI - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab,ATP-synt_ab_N TGS3_k127_6808697_19 1123366.TH3_07492 1.76e-22 103.0 COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2UD3W@28211|Alphaproteobacteria,2JSQE@204441|Rhodospirillales 204441|Rhodospirillales K Belongs to the MraZ family mraZ - - ko:K03925 - - - - ko00000 - - - MraZ TGS3_k127_6808697_10 1038860.AXAP01000065_gene3598 1.118e-84 291.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2TRQA@28211|Alphaproteobacteria,3JT8T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 TGS3_k127_6812600_2 1247963.JPHU01000001_gene1777 3.589e-135 433.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2TTP8@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate prpB - 4.1.3.30 ko:K03417 ko00640,map00640 - R00409 RC00286,RC00287 ko00000,ko00001,ko01000 - - - PEP_mutase TGS3_k127_6812600_1 314260.PB2503_07042 3.32e-177 580.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TV99@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the citrate synthase family prpC - 2.3.3.1,2.3.3.5 ko:K01647,ko:K01659 ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351,R00931 RC00004,RC00067,RC00406,RC02827 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt TGS3_k127_6812600_7 78245.Xaut_3924 1.675e-12 71.0 COG5450@1|root,COG5450@2|Bacteria,1N75T@1224|Proteobacteria,2UFNE@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Bacterial antitoxin of type II TA system, VapB - - - - - - - - - - - - VapB_antitoxin TGS3_k127_6812600_4 745310.G432_01850 6.825e-85 289.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,2TSZI@28211|Alphaproteobacteria,2K0QV@204457|Sphingomonadales 204457|Sphingomonadales H GTP cyclohydrolase folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI TGS3_k127_6812600_3 402881.Plav_3661 2.808e-119 388.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,1JNH3@119043|Rhodobiaceae 28211|Alphaproteobacteria I PFAM Enoyl-CoA hydratase isomerase MA20_15895 - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 TGS3_k127_6812600_0 1247963.JPHU01000008_gene2827 1.992e-205 657.0 COG0025@1|root,COG0025@2|Bacteria,1QTUE@1224|Proteobacteria,2TW3I@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0025 NhaP-type Na H and K H antiporters - - - - - - - - - - - - Na_H_Exchanger,TrkA_N TGS3_k127_6812600_6 1247963.JPHU01000008_gene2828 2.307e-41 164.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA TGS3_k127_6812600_5 1267005.KB911256_gene1882 1.143e-81 283.0 COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,2TUN9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function DUF87 MA20_26515 - - ko:K06915 - - - - ko00000 - - - DUF87 TGS3_k127_6824161_1 1123053.AUDG01000007_gene3128 9.899e-177 567.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF885 TGS3_k127_6824161_0 1449065.JMLL01000010_gene679 7.21e-263 821.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria,43HY2@69277|Phyllobacteriaceae 28211|Alphaproteobacteria I acyl-CoA dehydrogenase MA20_19860 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N TGS3_k127_6824161_2 1247963.JPHU01000011_gene832 6.298e-72 273.0 COG0790@1|root,COG1196@1|root,COG0790@2|Bacteria,COG1196@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Sel1 domain protein repeat-containing protein - - - ko:K07126,ko:K13582 ko04112,map04112 - - - ko00000,ko00001 - - - PG_binding_1,Sel1 TGS3_k127_6824161_3 715226.ABI_44280 3.099e-65 237.0 COG0627@1|root,COG0627@2|Bacteria,1QIRQ@1224|Proteobacteria,2U23Q@28211|Alphaproteobacteria,2KHJT@204458|Caulobacterales 204458|Caulobacterales S esterase - - - - - - - - - - - - Esterase TGS3_k127_6824161_7 1149133.ppKF707_1457 9.001e-08 62.0 COG0695@1|root,COG0695@2|Bacteria,1N8TV@1224|Proteobacteria,1T1J4@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Protein of unknown function (DUF3429) - - - - - - - - - - - - DUF3429 TGS3_k127_6824161_8 1122137.AQXF01000001_gene3207 1.511e-07 60.0 294XR@1|root,2ZSAQ@2|Bacteria 2|Bacteria S Heavy-metal resistance - - - - - - - - - - - - Metal_resist TGS3_k127_6824161_4 1229204.AMYY01000003_gene970 2.395e-51 188.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U5A1@28211|Alphaproteobacteria,4BSSY@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria K Sigma-70, region 4 sigE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 TGS3_k127_6824161_9 228405.HNE_1317 0.000737 48.0 COG5126@1|root,COG5126@2|Bacteria,1NH5D@1224|Proteobacteria,2UF3D@28211|Alphaproteobacteria,43YVF@69657|Hyphomonadaceae 28211|Alphaproteobacteria DTZ EF-hand, calcium binding motif - - - - - - - - - - - - EF-hand_1,EF-hand_5 TGS3_k127_6824161_5 1122612.AUBA01000006_gene2489 4.936e-13 81.0 COG0404@1|root,COG3665@1|root,COG0404@2|Bacteria,COG3665@2|Bacteria,1R3WG@1224|Proteobacteria,2TVX2@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the GcvT family - - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - DUF1989,GCV_T,GCV_T_C TGS3_k127_6824161_6 247639.MGP2080_04860 5.86e-12 79.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria 1224|Proteobacteria Q COG1233 Phytoene dehydrogenase and related proteins - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 TGS3_k127_6844295_1 1247963.JPHU01000013_gene702 1.683e-64 226.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG1520 FOG WD40-like repeat bamB - - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 TGS3_k127_6844295_0 1122132.AQYH01000010_gene3917 1.394e-173 555.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2TT38@28211|Alphaproteobacteria,4B90F@82115|Rhizobiaceae 28211|Alphaproteobacteria S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 TGS3_k127_6845129_0 314260.PB2503_08409 2.232e-232 732.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria 28211|Alphaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N TGS3_k127_6845129_1 391595.RLO149_c022310 2.844e-160 519.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TUMJ@28211|Alphaproteobacteria,2P1JK@2433|Roseobacter 28211|Alphaproteobacteria E COG0520 Selenocysteine lyase - - - - - - - - - - - - Aminotran_5 TGS3_k127_6858870_1 868595.Desca_2716 9.643e-17 92.0 COG0739@1|root,COG3583@1|root,COG0739@2|Bacteria,COG3583@2|Bacteria,1TRWJ@1239|Firmicutes,24A2J@186801|Clostridia,260WV@186807|Peptococcaceae 186801|Clostridia M PFAM Peptidase family M23 - - - - - - - - - - - - G5,LysM,Peptidase_M23 TGS3_k127_6858870_0 1122137.AQXF01000003_gene1870 4.579e-290 915.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran TGS3_k127_6870392_4 314260.PB2503_04752 1.806e-09 60.0 COG0438@1|root,COG0438@2|Bacteria,1PEWW@1224|Proteobacteria,2U2ZQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 TGS3_k127_6870392_3 1247963.JPHU01000003_gene1221 4.319e-50 184.0 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2U5IC@28211|Alphaproteobacteria 28211|Alphaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP TGS3_k127_6870392_0 1122132.AQYH01000007_gene1877 1.253e-266 827.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2TQYK@28211|Alphaproteobacteria,4BA0K@82115|Rhizobiaceae 28211|Alphaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N TGS3_k127_6870392_2 314260.PB2503_05202 1.234e-116 385.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2TR11@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt TGS3_k127_6870392_1 1535287.JP74_19020 7.355e-198 619.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2TRGP@28211|Alphaproteobacteria,3N6D9@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N TGS3_k127_6871651_1 1247963.JPHU01000001_gene1879 5.664e-30 124.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2TSCN@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase III alpha subunit dnaE GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon TGS3_k127_6871651_0 1537715.JQFJ01000002_gene503 1.384e-133 432.0 COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2TU8W@28211|Alphaproteobacteria,2K0IC@204457|Sphingomonadales 204457|Sphingomonadales I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 TGS3_k127_6890185_1 1280950.HJO_08629 4.163e-96 327.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2TRMJ@28211|Alphaproteobacteria,43XA2@69657|Hyphomonadaceae 28211|Alphaproteobacteria L ATP-dependent helicase HrpB hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C TGS3_k127_6890185_0 909613.UO65_2984 9.455e-164 529.0 COG0160@1|root,COG0160@2|Bacteria,2GKVH@201174|Actinobacteria,4DZMQ@85010|Pseudonocardiales 201174|Actinobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 1.2.1.18,1.2.1.27,2.6.1.19 ko:K00140,ko:K00823 ko00250,ko00280,ko00410,ko00562,ko00640,ko00650,ko01100,ko01120,ko01200,map00250,map00280,map00410,map00562,map00640,map00650,map01100,map01120,map01200 M00013,M00027 R00705,R00706,R00908,R00922,R00935,R01648 RC00004,RC00006,RC00062,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 TGS3_k127_6902665_3 1282876.BAOK01000001_gene3030 1.273e-08 64.0 COG3386@1|root,COG3386@2|Bacteria,1RFF0@1224|Proteobacteria,2U8ZK@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Arylesterase - - - - - - - - - - - - Arylesterase TGS3_k127_6902665_2 1380391.JIAS01000011_gene5255 1.015e-71 255.0 COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2TTTU@28211|Alphaproteobacteria,2JPSX@204441|Rhodospirillales 204441|Rhodospirillales M NmrA-like family - - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase TGS3_k127_6902665_1 1089552.KI911559_gene1988 2.813e-95 323.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2TR79@28211|Alphaproteobacteria,2JQDQ@204441|Rhodospirillales 204441|Rhodospirillales H Belongs to the FPP GGPP synthase family ispA - 2.5.1.1,2.5.1.10 ko:K00795 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364 R01658,R02003 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt TGS3_k127_6902665_0 1380391.JIAS01000011_gene5262 3.11e-135 437.0 COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2TRNR@28211|Alphaproteobacteria,2JR15@204441|Rhodospirillales 204441|Rhodospirillales IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB TGS3_k127_6909077_2 1121123.AUAO01000003_gene2473 6.09e-104 345.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,2TQUR@28211|Alphaproteobacteria,2KFR0@204458|Caulobacterales 204458|Caulobacterales N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP TGS3_k127_6909077_4 314260.PB2503_08489 1.101e-67 244.0 COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,2U06N@28211|Alphaproteobacteria 28211|Alphaproteobacteria N COG1419 Flagellar GTP-binding protein flhF - - ko:K02404 - - - - ko00000,ko02035 - - - SRP54 TGS3_k127_6909077_1 1238182.C882_3688 1.21e-114 379.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TR60@28211|Alphaproteobacteria,2JQQP@204441|Rhodospirillales 204441|Rhodospirillales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C TGS3_k127_6909077_6 1131814.JAFO01000001_gene2313 1.349e-13 78.0 COG2214@1|root,COG2214@2|Bacteria,1PUS9@1224|Proteobacteria,2TT35@28211|Alphaproteobacteria,3EZSI@335928|Xanthobacteraceae 28211|Alphaproteobacteria O Heat shock protein MA20_36100 - - - - - - - - - - - DnaJ TGS3_k127_6909077_3 1230476.C207_05763 3.255e-78 275.0 COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,2TUE7@28211|Alphaproteobacteria,3JXD9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate TGS3_k127_6909077_0 1280948.HY36_07080 2.861e-136 441.0 COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2TUQ1@28211|Alphaproteobacteria,43ZH2@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Putative cyclase - - - - - - - - - - - - Cyclase TGS3_k127_6943752_3 1282876.BAOK01000001_gene2567 1.884e-05 56.0 28K9G@1|root,2Z9X1@2|Bacteria,1NEMY@1224|Proteobacteria,2U0J7@28211|Alphaproteobacteria,4BSY8@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria - - MA20_15515 - - - - - - - - - - - - TGS3_k127_6943752_1 394221.Mmar10_0941 6.4e-91 315.0 COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,2TQN7@28211|Alphaproteobacteria,43WTI@69657|Hyphomonadaceae 28211|Alphaproteobacteria O COG1073 Hydrolases of the alpha beta superfamily - - - ko:K06889,ko:K07397 - - - - ko00000 - - - Hydrolase_4,OsmC TGS3_k127_6943752_0 1247963.JPHU01000008_gene2779 1.552e-123 419.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Belongs to the peptidase S1C family dop GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 TGS3_k127_6943752_2 314260.PB2503_08144 2.133e-53 190.0 COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2TRTZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain ragA GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C TGS3_k127_6957121_3 266834.SMc02096 5.78e-31 125.0 COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2U9ED@28211|Alphaproteobacteria,4B785@82115|Rhizobiaceae 28211|Alphaproteobacteria I Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 TGS3_k127_6957121_1 1238182.C882_4157 1.183e-141 461.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2TSD1@28211|Alphaproteobacteria,2JQ6Y@204441|Rhodospirillales 204441|Rhodospirillales I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr - 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom TGS3_k127_6957121_2 1247963.JPHU01000007_gene1617 1.826e-123 409.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2TQXJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 TGS3_k127_6957121_0 1247963.JPHU01000007_gene1618 2.39e-192 613.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA TGS3_k127_697078_1 59538.XP_005969845.1 1.701e-178 564.0 COG0436@1|root,KOG0257@2759|Eukaryota,38BZ0@33154|Opisthokonta,3BCG1@33208|Metazoa,3CRCR@33213|Bilateria,484V9@7711|Chordata,492K3@7742|Vertebrata 33208|Metazoa E kynurenine-glyoxylate transaminase activity - - - - - - - - - - - - Aminotran_1_2 TGS3_k127_697078_2 331869.BAL199_26801 3.027e-129 421.0 COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,2TSPE@28211|Alphaproteobacteria,4BP5E@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G Bacterial fructose-1,6-bisphosphatase, glpX-encoded glpX - 3.1.3.11,3.1.3.37 ko:K02446,ko:K11532 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R01845,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX TGS3_k127_697078_0 411684.HPDFL43_13907 5.401e-275 857.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,43HRF@69277|Phyllobacteriaceae 28211|Alphaproteobacteria V ABC-type multidrug transport system ATPase and permease abcT3 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K06147,ko:K18893 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran TGS3_k127_697078_3 3988.XP_002537172.1 2.399e-122 396.0 COG0624@1|root,KOG2276@2759|Eukaryota,37Y7K@33090|Viridiplantae 33090|Viridiplantae E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 TGS3_k127_6977474_6 1117943.SFHH103_00871 1.3e-130 421.0 COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2TURP@28211|Alphaproteobacteria,4BDDJ@82115|Rhizobiaceae 28211|Alphaproteobacteria L Transposase DDE domain - - - ko:K07492 - - - - ko00000 - - - DDE_Tnp_1,DDE_Tnp_1_2,DUF4096 TGS3_k127_6977474_5 1209072.ALBT01000029_gene2212 2.697e-153 497.0 COG3211@1|root,COG3211@2|Bacteria,1QY0R@1224|Proteobacteria,1S13A@1236|Gammaproteobacteria,1FHEH@10|Cellvibrio 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 TGS3_k127_6977474_4 622637.KE124774_gene1434 2.634e-169 547.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2TT84@28211|Alphaproteobacteria,36X5Y@31993|Methylocystaceae 28211|Alphaproteobacteria S Uncharacterized ACR, YdiU/UPF0061 family - - - - - - - - - - - - UPF0061 TGS3_k127_6977474_16 1346791.M529_06100 3.788e-27 126.0 COG4713@1|root,COG4713@2|Bacteria,1RB29@1224|Proteobacteria,2UUUW@28211|Alphaproteobacteria,2K98X@204457|Sphingomonadales 204457|Sphingomonadales S Predicted membrane protein (DUF2142) - - - - - - - - - - - - DUF2142 TGS3_k127_6977474_3 314260.PB2503_08549 2.363e-181 582.0 2C5WB@1|root,2Z7IZ@2|Bacteria,1RCRD@1224|Proteobacteria,2UEX3@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_6977474_0 1280952.HJA_11579 2.023e-237 754.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TUXY@28211|Alphaproteobacteria,44105@69657|Hyphomonadaceae 28211|Alphaproteobacteria EU Dienelactone hydrolase family - - - - - - - - - - - - PD40,Peptidase_S9 TGS3_k127_6977474_9 1247963.JPHU01000004_gene501 1.233e-77 271.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TVQR@28211|Alphaproteobacteria 28211|Alphaproteobacteria K esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin TGS3_k127_6977474_20 450851.PHZ_c0924 2.456e-20 95.0 COG1815@1|root,COG1815@2|Bacteria,1N1G1@1224|Proteobacteria,2UCJ4@28211|Alphaproteobacteria,2KH1U@204458|Caulobacterales 204458|Caulobacterales N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body flgB - - ko:K02387 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod TGS3_k127_6977474_14 323098.Nwi_1133 7.689e-41 154.0 COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,2U94I@28211|Alphaproteobacteria,3JY7J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Belongs to the flagella basal body rod proteins family flgC - - ko:K02388 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C TGS3_k127_6977474_21 856793.MICA_1700 1.919e-12 70.0 COG1677@1|root,COG1677@2|Bacteria,1N7KU@1224|Proteobacteria,2UF4S@28211|Alphaproteobacteria,4BR49@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria N Flagellar hook-basal body complex protein FliE fliE - - ko:K02408 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliE TGS3_k127_6977474_19 102125.Xen7305DRAFT_00021860 3.798e-21 100.0 2DMQR@1|root,32T24@2|Bacteria,1G7XE@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - TGS3_k127_6977474_1 1415780.JPOG01000001_gene551 1.08e-214 686.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1RPIW@1236|Gammaproteobacteria,1X55F@135614|Xanthomonadales 135614|Xanthomonadales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 TGS3_k127_6977474_18 582402.Hbal_0254 3.748e-23 101.0 COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,2UBX6@28211|Alphaproteobacteria,43YFP@69657|Hyphomonadaceae 28211|Alphaproteobacteria N Flagellar biosynthesis fliQ - - ko:K02420 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_3 TGS3_k127_6977474_11 1333998.M2A_1219 2.894e-56 209.0 COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,2TTHN@28211|Alphaproteobacteria,4BQTZ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria N Role in flagellar biosynthesis fliR - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 TGS3_k127_6977474_8 394221.Mmar10_1930 1.407e-84 292.0 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,2TS13@28211|Alphaproteobacteria,43WUC@69657|Hyphomonadaceae 28211|Alphaproteobacteria NU FlhB HrpN YscU SpaS family protein flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 TGS3_k127_6977474_17 1127673.GLIP_2159 5.149e-27 127.0 COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S876@1236|Gammaproteobacteria 1236|Gammaproteobacteria S cAMP biosynthetic process - - - - - - - - - - - - - TGS3_k127_6977474_2 314260.PB2503_12064 1.302e-211 687.0 COG0784@1|root,COG3852@1|root,COG0784@2|Bacteria,COG3852@2|Bacteria,1NC9X@1224|Proteobacteria,2TXEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria T histidine kinase A domain protein - - 2.7.13.3 ko:K13587 ko02020,ko04112,map02020,map04112 M00512 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,Response_reg,dCache_2 TGS3_k127_6977474_10 266809.PM03_13575 5.853e-67 235.0 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2TTFF@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T TGS3_k127_6977474_13 314260.PB2503_04557 3.077e-46 171.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2UBTB@28211|Alphaproteobacteria 28211|Alphaproteobacteria U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB TGS3_k127_6977474_12 1247963.JPHU01000002_gene2638 5.509e-48 179.0 COG4395@1|root,COG4395@2|Bacteria,1NCIX@1224|Proteobacteria,2TTDQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S import inner membrane translocase, subunit Tim44 MA20_24770 - - - - - - - - - - - Tim44 TGS3_k127_6977474_7 1247963.JPHU01000002_gene2637 2.002e-91 316.0 COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2TS5S@28211|Alphaproteobacteria 28211|Alphaproteobacteria M membrane-bound lytic murein transglycosylase mltA - - ko:K08304 - - - - ko00000,ko01000,ko01011 - GH102 - 3D,MltA TGS3_k127_6977474_15 1247963.JPHU01000002_gene2636 3.485e-29 129.0 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2UCM1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Smr protein MutS2 smrA - - - - - - - - - - - Smr TGS3_k127_6985530_7 1247963.JPHU01000004_gene487 6.689e-65 229.0 COG1216@1|root,COG1216@2|Bacteria,1N6DH@1224|Proteobacteria,2TWBP@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 TGS3_k127_6985530_10 391589.RGAI101_253 1.403e-48 182.0 COG3222@1|root,COG3222@2|Bacteria,1RB1V@1224|Proteobacteria,2TT1J@28211|Alphaproteobacteria,2P2XW@2433|Roseobacter 28211|Alphaproteobacteria S protein conserved in bacteria - - - ko:K09931 - - - - ko00000 - - - DUF2064 TGS3_k127_6985530_2 1380394.JADL01000005_gene5480 4.775e-141 474.0 COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,2TVX5@28211|Alphaproteobacteria,2JYVI@204441|Rhodospirillales 204441|Rhodospirillales P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K16090 - - - - ko00000,ko02000 1.B.14.1.11 - - Plug,TonB_dep_Rec TGS3_k127_6985530_8 1095769.CAHF01000010_gene1166 2.031e-64 228.0 COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,2VJHT@28216|Betaproteobacteria,473KF@75682|Oxalobacteraceae 28216|Betaproteobacteria C PKHD-type hydroxylase piuC - - ko:K07336 - - - - ko00000,ko01000 - - - 2OG-FeII_Oxy_3 TGS3_k127_6985530_9 1366050.N234_09200 3.962e-50 183.0 COG0346@1|root,COG0346@2|Bacteria,1N0WM@1224|Proteobacteria,2VSM4@28216|Betaproteobacteria,1K905@119060|Burkholderiaceae 28216|Betaproteobacteria E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase TGS3_k127_6985530_4 1161401.ASJA01000001_gene433 4.621e-127 418.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,43XBZ@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Membrane dipeptidase (Peptidase family M19) - - - - - - - - - - - - Peptidase_M19 TGS3_k127_6985530_12 1449076.JOOE01000002_gene1322 2.273e-37 147.0 2DMMQ@1|root,32SHK@2|Bacteria,1N2WS@1224|Proteobacteria,2UC62@28211|Alphaproteobacteria,2K5BZ@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - DUF3052 TGS3_k127_6985530_3 1280947.HY30_10080 5.883e-137 443.0 COG1609@1|root,COG1609@2|Bacteria,1MW7E@1224|Proteobacteria,2U1NM@28211|Alphaproteobacteria,43W6V@69657|Hyphomonadaceae 28211|Alphaproteobacteria K Periplasmic binding protein domain - - - - - - - - - - - - LacI,Peripla_BP_3 TGS3_k127_6985530_13 1408254.T458_21085 2.058e-32 129.0 COG0662@1|root,COG0662@2|Bacteria,1V7K2@1239|Firmicutes,4HN60@91061|Bacilli,26WT8@186822|Paenibacillaceae 91061|Bacilli G Mannose-6-phosphate isomerase - - - - - - - - - - - - Cupin_2 TGS3_k127_6985530_6 1297742.A176_06102 2.747e-69 255.0 COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,438C4@68525|delta/epsilon subdivisions,2WYM4@28221|Deltaproteobacteria,2YWIJ@29|Myxococcales 28221|Deltaproteobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1 TGS3_k127_6985530_11 1121106.JQKB01000014_gene5651 1.426e-38 153.0 COG0500@1|root,COG2226@2|Bacteria,1QYPC@1224|Proteobacteria,2TXUB@28211|Alphaproteobacteria,2JZ2T@204441|Rhodospirillales 204441|Rhodospirillales Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 TGS3_k127_6985530_5 292415.Tbd_1279 1.593e-70 252.0 COG3528@1|root,COG3528@2|Bacteria,1R601@1224|Proteobacteria,2VPGW@28216|Betaproteobacteria 28216|Betaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2219) - - - - - - - - - - - - DUF2219 TGS3_k127_6985530_1 1247963.JPHU01000006_gene164 1.05e-148 475.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2TQKB@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA TGS3_k127_6985530_0 1247963.JPHU01000006_gene165 0.0 1455.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr TGS3_k127_6985530_14 765698.Mesci_2411 5.258e-25 109.0 2DNS7@1|root,32YWC@2|Bacteria,1QU0X@1224|Proteobacteria,2UF1N@28211|Alphaproteobacteria,43KPI@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP TGS3_k127_6985530_15 1122962.AULH01000004_gene2340 1.49e-16 79.0 COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria,36XAE@31993|Methylocystaceae 28211|Alphaproteobacteria C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding TGS3_k127_6988617_3 371731.Rsw2DRAFT_0028 3.104e-08 64.0 2ERFR@1|root,33J1A@2|Bacteria,1NNJF@1224|Proteobacteria,2UNK4@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_6988617_0 1280950.HJO_07712 2.266e-223 702.0 COG1473@1|root,COG1473@2|Bacteria,1MX6N@1224|Proteobacteria,2UQ2S@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 TGS3_k127_6988617_1 1121124.JNIX01000013_gene1573 2.143e-79 273.0 COG1335@1|root,COG1335@2|Bacteria,1MWFQ@1224|Proteobacteria,2TUZG@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Amidases related to nicotinamidase - - - - - - - - - - - - Isochorismatase TGS3_k127_6988617_2 1278073.MYSTI_06155 3.264e-21 104.0 COG2207@1|root,COG2207@2|Bacteria,1QKC9@1224|Proteobacteria,42XG8@68525|delta/epsilon subdivisions,2WT82@28221|Deltaproteobacteria 28221|Deltaproteobacteria K helix_turn_helix, arabinose operon control protein - - - ko:K07506 - - - - ko00000,ko03000 - - - HTH_18 TGS3_k127_7000336_4 715226.ABI_07400 3.651e-12 72.0 COG4709@1|root,COG4709@2|Bacteria 2|Bacteria S membrane - - - - - - - - - - - - Sensor TGS3_k127_7000336_3 1121933.AUHH01000011_gene2741 3.841e-20 94.0 COG1695@1|root,COG1695@2|Bacteria,2GRHC@201174|Actinobacteria,4DV0A@85009|Propionibacteriales 201174|Actinobacteria K Transcriptional regulator PadR-like family - - - ko:K10947 - - - - ko00000,ko03000 - - - PadR TGS3_k127_7000336_1 1089551.KE386572_gene4558 3.535e-82 284.0 COG3440@1|root,COG3440@2|Bacteria,1NE0N@1224|Proteobacteria,2TV2B@28211|Alphaproteobacteria,4BR4S@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria V HNH endonuclease - - - ko:K07454 - - - - ko00000 - - - HNH_2 TGS3_k127_7000336_0 1247963.JPHU01000001_gene1906 4.098e-173 546.0 COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2TS2N@28211|Alphaproteobacteria 28211|Alphaproteobacteria J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e TGS3_k127_7000336_2 991905.SL003B_4281 8.073e-38 150.0 COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,2UBYC@28211|Alphaproteobacteria,4BSJ8@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O Phospholipid methyltransferase - - - - - - - - - - - - PEMT TGS3_k127_7015517_2 1479238.JQMZ01000001_gene1070 2.067e-38 147.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VFCG@28211|Alphaproteobacteria,4411Z@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Sodium:solute symporter family - - - - - - - - - - - - SSF TGS3_k127_7015517_1 1547437.LL06_14175 9.876e-55 202.0 COG1396@1|root,COG1396@2|Bacteria,1MWUC@1224|Proteobacteria,2TU04@28211|Alphaproteobacteria,43I0E@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K Helix-turn-helix MA20_08830 - - - - - - - - - - - HTH_3,HTH_31 TGS3_k127_7015517_3 1120966.AUBU01000018_gene250 9.155e-20 94.0 293BF@1|root,2ZQU3@2|Bacteria,4NNXE@976|Bacteroidetes,47Q3I@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - TGS3_k127_7015517_0 314260.PB2503_10574 5.816e-210 659.0 COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2TSQH@28211|Alphaproteobacteria 28211|Alphaproteobacteria F COG0044 Dihydroorotase and related cyclic amidohydrolases pyrC1 - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 TGS3_k127_7020124_5 391595.RLO149_p630460 2.377e-21 97.0 COG0457@1|root,COG0457@2|Bacteria,1N8DP@1224|Proteobacteria,2TYCN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Sulfotransferase family - - - - - - - - - - - - - TGS3_k127_7020124_1 460265.Mnod_3440 4.436e-76 267.0 COG3246@1|root,COG3246@2|Bacteria,1R4YF@1224|Proteobacteria,2TVC8@28211|Alphaproteobacteria,1JX4G@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Pfam:Kce - - - - - - - - - - - - BKACE TGS3_k127_7020124_3 1121946.AUAX01000031_gene994 8.985e-55 198.0 COG2227@1|root,COG2227@2|Bacteria,2ID2Z@201174|Actinobacteria,4DD23@85008|Micromonosporales 201174|Actinobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25 TGS3_k127_7020124_2 472759.Nhal_0662 8.628e-64 236.0 COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,1RRGY@1236|Gammaproteobacteria,1WVVW@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4010) - - - - - - - - - - - - DUF4010,MgtC TGS3_k127_7020124_0 228405.HNE_0234 1.78e-169 545.0 28JVF@1|root,2Z9KD@2|Bacteria,1MXZ6@1224|Proteobacteria,2TR1P@28211|Alphaproteobacteria,43ZFB@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_7020124_4 582402.Hbal_1961 1.72e-44 169.0 28HJ1@1|root,2Z7UB@2|Bacteria,1R3FN@1224|Proteobacteria,2U1R7@28211|Alphaproteobacteria,43ZEB@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_7029701_5 1123503.KB908056_gene1302 0.0006945 49.0 2E0PV@1|root,32W8K@2|Bacteria,1N197@1224|Proteobacteria,2UCAE@28211|Alphaproteobacteria,2KH4C@204458|Caulobacterales 204458|Caulobacterales - - flbY - - - - - - - - - - - - TGS3_k127_7029701_3 551789.ATVJ01000003_gene260 1.149e-10 70.0 COG3951@1|root,COG3951@2|Bacteria,1N7K5@1224|Proteobacteria,2UFY2@28211|Alphaproteobacteria,43YUE@69657|Hyphomonadaceae 28211|Alphaproteobacteria MNO Rod binding protein cheL - - - - - - - - - - - Rod-binding TGS3_k127_7029701_0 1161401.ASJA01000004_gene2350 2.511e-139 453.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2TQNX@28211|Alphaproteobacteria,43WRI@69657|Hyphomonadaceae 28211|Alphaproteobacteria N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgI GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI TGS3_k127_7029701_4 1089552.KI911559_gene2589 5.519e-07 57.0 2E5SK@1|root,330GZ@2|Bacteria,1N7R1@1224|Proteobacteria,2UFAX@28211|Alphaproteobacteria,2JTWZ@204441|Rhodospirillales 204441|Rhodospirillales N Class II flagellar assembly regulator fliX - - - - - - - - - - - FliX TGS3_k127_7029701_1 1122962.AULH01000007_gene1915 1.995e-57 203.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2U74V@28211|Alphaproteobacteria,36Y53@31993|Methylocystaceae 28211|Alphaproteobacteria T Prokaryotic dksA/traR C4-type zinc finger dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR TGS3_k127_7029701_2 1161401.ASJA01000002_gene2687 6.937e-35 152.0 COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,2TWNB@28211|Alphaproteobacteria 28211|Alphaproteobacteria M membrane - - - - - - - - - - - - DUF2339 TGS3_k127_7032747_5 1230476.C207_02905 2.698e-17 82.0 COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,2TSKC@28211|Alphaproteobacteria,3JW6P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Belongs to the NifH BchL ChlL family bchX - 1.3.7.14,1.3.7.15 ko:K11333 ko00860,ko01110,map00860,map01110 - R09053,R09060 RC01008 ko00000,ko00001,ko01000 - - - Fer4_NifH TGS3_k127_7032747_0 114615.BRADO1619 1.703e-254 794.0 COG2710@1|root,COG2710@2|Bacteria,1MUGI@1224|Proteobacteria,2TU7U@28211|Alphaproteobacteria,3JXNG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C reductase subunit bchY - 1.3.7.14,1.3.7.15 ko:K11334 ko00860,ko01110,map00860,map01110 - R09053,R09060 RC01008 ko00000,ko00001,ko01000 - - - Oxidored_nitro TGS3_k127_7032747_1 1120956.JHZK01000006_gene642 1.048e-247 777.0 COG2710@1|root,COG2710@2|Bacteria,1MW4U@1224|Proteobacteria,2TT9B@28211|Alphaproteobacteria 28211|Alphaproteobacteria C chlorophyllide reductase subunit Z bchZ - 1.3.7.14,1.3.7.15 ko:K11335 ko00860,ko01110,map00860,map01110 - R09053,R09060 RC01008 ko00000,ko00001,ko01000 - - - Oxidored_nitro,PCP_red TGS3_k127_7032747_4 426117.M446_3701 4.209e-23 100.0 2DPVW@1|root,333MC@2|Bacteria,1N7PY@1224|Proteobacteria,2UHIR@28211|Alphaproteobacteria,1JVPT@119045|Methylobacteriaceae 28211|Alphaproteobacteria C Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers pufB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08927 ko02020,map02020 - - - ko00000,ko00001,ko00194 - - - LHC TGS3_k127_7032747_6 1156935.QWE_04133 6.372e-16 78.0 2EI15@1|root,33BSN@2|Bacteria,1N7FB@1224|Proteobacteria,2UFDP@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers pufA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08926 ko02020,map02020 - - - ko00000,ko00001,ko00194 - - - LHC TGS3_k127_7032747_3 1121124.JNIX01000001_gene973 7.875e-157 496.0 2DB77@1|root,2Z7K3@2|Bacteria,1NHMC@1224|Proteobacteria,2U06K@28211|Alphaproteobacteria 28211|Alphaproteobacteria S photosynthetic reaction center L subunit pufL GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009579,GO:0016020,GO:0034357,GO:0042716,GO:0042717,GO:0044424,GO:0044436,GO:0044444,GO:0044464 - ko:K08928 ko02020,map02020 M00597 - - ko00000,ko00001,ko00002,ko00194 - - - Photo_RC TGS3_k127_7032747_2 935548.KI912159_gene5494 5.031e-163 518.0 2DBBD@1|root,2Z87P@2|Bacteria,1MWZI@1224|Proteobacteria,2TT76@28211|Alphaproteobacteria,43MMV@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis pufM GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009579,GO:0016020,GO:0034357,GO:0042716,GO:0042717,GO:0044424,GO:0044436,GO:0044444,GO:0044464 - ko:K08929 ko02020,map02020 M00597 - - ko00000,ko00001,ko00002,ko00194 - - - Photo_RC TGS3_k127_7040959_4 1110502.TMO_0234 4.352e-36 138.0 COG4341@1|root,COG4341@2|Bacteria,1QHQD@1224|Proteobacteria,2U1W2@28211|Alphaproteobacteria,2JZT1@204441|Rhodospirillales 204441|Rhodospirillales S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - - - - - - - - - - HD TGS3_k127_7040959_0 190650.CC_1970 3.001e-244 777.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U10R@28211|Alphaproteobacteria,2KFMU@204458|Caulobacterales 204458|Caulobacterales P TonB-dependent Receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec TGS3_k127_7040959_3 1384054.N790_04610 6.318e-57 206.0 2C3PP@1|root,2Z954@2|Bacteria,1MXGR@1224|Proteobacteria,1S3GQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Branched-chain amino acid aminotransferase - - - - - - - - - - - - - TGS3_k127_7040959_5 1479238.JQMZ01000001_gene20 1.244e-34 145.0 COG3801@1|root,COG3801@2|Bacteria,1Q19E@1224|Proteobacteria,2UC9N@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate - - - - - - - - - - - - YjbR TGS3_k127_7040959_2 588932.JHOF01000011_gene2333 4.74e-102 338.0 COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2TR90@28211|Alphaproteobacteria,2KF2Q@204458|Caulobacterales 204458|Caulobacterales S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox TGS3_k127_7040959_1 1122137.AQXF01000001_gene3131 5.618e-130 422.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TQR9@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase - - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 TGS3_k127_7075383_4 1131813.AQVT01000001_gene2871 4.215e-31 126.0 29Q66@1|root,30B54@2|Bacteria,1N9YZ@1224|Proteobacteria,2TS6J@28211|Alphaproteobacteria,1JSG9@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF4166) - - - - - - - - - - - - DUF4166 TGS3_k127_7075383_1 1038862.KB893873_gene7640 1.533e-153 500.0 COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,2TRY5@28211|Alphaproteobacteria,3JRAI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF1731) - - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase TGS3_k127_7075383_3 1267005.KB911258_gene428 1.657e-66 230.0 COG3011@1|root,COG3011@2|Bacteria,1N0YV@1224|Proteobacteria,2UAQR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function, DUF393 - - - - - - - - - - - - DUF393 TGS3_k127_7075383_6 686340.Metal_1646 5.11e-06 51.0 COG4118@1|root,COG4118@2|Bacteria,1NH4W@1224|Proteobacteria,1THUX@1236|Gammaproteobacteria,1XFSW@135618|Methylococcales 135618|Methylococcales D Antitoxin component of a toxin-antitoxin (TA) module - - - - - - - - - - - - PhdYeFM_antitox TGS3_k127_7075383_5 1123389.ATXJ01000004_gene1304 1.444e-21 99.0 COG3744@1|root,COG3744@2|Bacteria,1WKGM@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PilT protein domain protein - - - - - - - - - - - - PIN TGS3_k127_7075383_2 565045.NOR51B_313 4.665e-83 282.0 COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,1RTU6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE TGS3_k127_7075383_0 1247963.JPHU01000001_gene1781 4.558e-189 594.0 COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2TU37@28211|Alphaproteobacteria 28211|Alphaproteobacteria S 2-methylcitrate dehydratase prpD - 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - - MmgE_PrpD TGS3_k127_7081418_1 366602.Caul_3974 2.039e-101 338.0 COG3662@1|root,COG3662@2|Bacteria,1R50Q@1224|Proteobacteria,2TSG5@28211|Alphaproteobacteria,2KI9P@204458|Caulobacterales 204458|Caulobacterales S Uncharacterized protein conserved in bacteria (DUF2236) - - - - - - - - - - - - DUF2236 TGS3_k127_7081418_0 402881.Plav_2318 5.086e-155 496.0 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2TR8A@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG0500 SAM-dependent methyltransferases - - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_11,Methyltransf_31 TGS3_k127_7081418_3 279238.Saro_2352 4.104e-27 118.0 2DM9Y@1|root,32AJ6@2|Bacteria,1N98N@1224|Proteobacteria,2UFUN@28211|Alphaproteobacteria,2K7UM@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - TGS3_k127_7081418_2 1123269.NX02_29030 1.029e-71 252.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TRNX@28211|Alphaproteobacteria,2K2U3@204457|Sphingomonadales 204457|Sphingomonadales E C-terminus of AA_permease - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 TGS3_k127_7104423_3 1110502.TMO_0779 8.578e-13 75.0 COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,2UCUE@28211|Alphaproteobacteria,2JU4D@204441|Rhodospirillales 204441|Rhodospirillales L Staphylococcal nuclease homologue - - - - - - - - - - - - SNase TGS3_k127_7104423_2 314260.PB2503_10229 1.225e-36 146.0 COG2032@1|root,COG2032@2|Bacteria,1RGV4@1224|Proteobacteria,2UC22@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodC GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.15.1.1 ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 - - - ko00000,ko00001,ko01000 - - - Sod_Cu TGS3_k127_7104423_0 1122613.ATUP01000001_gene361 1.581e-71 254.0 COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,2U0J2@28211|Alphaproteobacteria,43WKC@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Kelch motif - - - - - - - - - - - - Kelch_1,Kelch_2,Kelch_4,Kelch_6 TGS3_k127_7104423_1 983920.Y88_0321 2.706e-55 198.0 COG1940@1|root,COG1940@2|Bacteria,1R7YN@1224|Proteobacteria,2TUWX@28211|Alphaproteobacteria,2K1T7@204457|Sphingomonadales 204457|Sphingomonadales GK Transcriptional regulator sugar kinase - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK TGS3_k127_7104504_0 1282876.BAOK01000001_gene2057 0.0 1027.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria,4BPCY@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV TGS3_k127_7104504_2 1525715.IX54_07225 2.567e-63 221.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2U74H@28211|Alphaproteobacteria,2PUPS@265|Paracoccus 28211|Alphaproteobacteria H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like TGS3_k127_7104504_1 1247963.JPHU01000006_gene188 6.297e-101 338.0 COG0652@1|root,COG0652@2|Bacteria,1R62A@1224|Proteobacteria,2U3BZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - Pro_isomerase TGS3_k127_7104504_3 911045.PSE_3211 6.854e-61 214.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2U591@28211|Alphaproteobacteria 28211|Alphaproteobacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K01802,ko:K09565 ko04020,ko04022,ko05012,ko05016,ko05145,map04020,map04022,map05012,map05016,map05145 - - - ko00000,ko00001,ko01000,ko03110 - - - Pro_isomerase TGS3_k127_7104504_4 1219065.VPR01S_07_01860 2.459e-21 103.0 2A07X@1|root,30NB4@2|Bacteria,1N1WT@1224|Proteobacteria,1S9GH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3592) - - - - - - - - - - - - DUF3592 TGS3_k127_7111142_2 314260.PB2503_01387 1.584e-66 235.0 COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2TZPK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF502) MA20_12960 - - - - - - - - - - - DUF502 TGS3_k127_7111142_1 1161401.ASJA01000009_gene1736 7.205e-71 254.0 COG2267@1|root,COG2267@2|Bacteria,1MVDA@1224|Proteobacteria,2TUDQ@28211|Alphaproteobacteria,43XJQ@69657|Hyphomonadaceae 28211|Alphaproteobacteria I Protein of unknown function (DUF3089) - - - - - - - - - - - - DUF3089 TGS3_k127_7111142_0 1280954.HPO_03219 5.907e-113 371.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2TRT6@28211|Alphaproteobacteria,43X4K@69657|Hyphomonadaceae 28211|Alphaproteobacteria M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase TGS3_k127_7117972_2 1342302.JASC01000013_gene2682 7.152e-08 59.0 29E4R@1|root,3012N@2|Bacteria,1PS0A@1224|Proteobacteria,2V47H@28211|Alphaproteobacteria,3ZZ4Q@60136|Sulfitobacter 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_7117972_0 1144343.PMI41_00532 3.555e-65 234.0 COG2267@1|root,COG2267@2|Bacteria,1RF71@1224|Proteobacteria,2USB0@28211|Alphaproteobacteria,43PZW@69277|Phyllobacteriaceae 28211|Alphaproteobacteria I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 TGS3_k127_7117972_1 1035191.HMPREF0185_01384 1.709e-33 133.0 COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,2UCNX@28211|Alphaproteobacteria,2KH7I@204458|Caulobacterales 204458|Caulobacterales L domain protein - - - ko:K07461 - - - - ko00000 - - - GIY-YIG TGS3_k127_7128234_2 450851.PHZ_c1743 1.206e-45 166.0 COG0022@1|root,COG0508@1|root,COG0022@2|Bacteria,COG0508@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria,2KFI5@204458|Caulobacterales 204458|Caulobacterales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2 - - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl,Transket_pyr,Transketolase_C TGS3_k127_7128234_4 1247963.JPHU01000014_gene960 4.447e-06 55.0 COG3152@1|root,COG3152@2|Bacteria,1NDNG@1224|Proteobacteria,2TT9F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 TGS3_k127_7128234_0 1247963.JPHU01000014_gene962 8.508e-166 532.0 COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2TRXM@28211|Alphaproteobacteria 28211|Alphaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhC - 1.2.4.1,2.3.1.12 ko:K00162,ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R02569,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding TGS3_k127_7128234_1 1122970.AUHC01000008_gene174 1.758e-85 293.0 COG0500@1|root,COG2226@2|Bacteria,1RJ76@1224|Proteobacteria,2UJRG@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_25 TGS3_k127_7128234_5 1238182.C882_2613 2.221e-05 51.0 2EKKZ@1|root,33EAS@2|Bacteria,1NHDS@1224|Proteobacteria 1224|Proteobacteria S Putative transmembrane protein (PGPGW) - - - - - - - - - - - - PGPGW TGS3_k127_7128234_3 1123269.NX02_24210 1.228e-25 114.0 COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,2TRD1@28211|Alphaproteobacteria,2K0G7@204457|Sphingomonadales 204457|Sphingomonadales M Membrane bound O-acyl transferase, MBOAT family protein - - - - - - - - - - - - MBOAT TGS3_k127_7166364_1 1295642.H839_07279 0.0001643 51.0 2E9CG@1|root,333K5@2|Bacteria,1U9XV@1239|Firmicutes,4IK5K@91061|Bacilli,1WH9X@129337|Geobacillus 91061|Bacilli S Tissue inhibitor of metalloproteinase - - - - - - - - - - - - TIMP TGS3_k127_7166364_0 1120983.KB894577_gene3639 4.295e-64 233.0 COG3391@1|root,COG3391@2|Bacteria,1MXN7@1224|Proteobacteria,2TR83@28211|Alphaproteobacteria,1JNQP@119043|Rhodobiaceae 28211|Alphaproteobacteria S GTA TIM-barrel-like domain - - - - - - - - - - - - GTA_TIM,Phage-tail_3 TGS3_k127_717865_2 1122613.ATUP01000001_gene2117 1.083e-140 454.0 COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2TT2N@28211|Alphaproteobacteria,43WJM@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Aminoglycoside phosphotransferase - - - - - - - - - - - - APH TGS3_k127_717865_5 1280948.HY36_16365 2.159e-27 113.0 COG2119@1|root,COG2119@2|Bacteria,1PP1X@1224|Proteobacteria,2V9AT@28211|Alphaproteobacteria,440DU@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Uncharacterized protein family UPF0016 - - - - - - - - - - - - UPF0016 TGS3_k127_717865_3 1123020.AUIE01000045_gene5229 1.49e-91 309.0 COG0596@1|root,COG0596@2|Bacteria,1QIT9@1224|Proteobacteria,1RNP9@1236|Gammaproteobacteria,1YDBH@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 TGS3_k127_717865_1 316055.RPE_4612 1.902e-151 490.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2TQR5@28211|Alphaproteobacteria,3JSI5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N TGS3_k127_717865_8 582744.Msip34_1750 0.0005222 52.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,2KKGJ@206350|Nitrosomonadales 206350|Nitrosomonadales T response regulator receiver - - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,HATPase_c,Hpt,Response_reg TGS3_k127_717865_4 768671.ThimaDRAFT_0596 2.923e-86 302.0 COG3126@1|root,COG3187@1|root,COG3650@1|root,COG3126@2|Bacteria,COG3187@2|Bacteria,COG3650@2|Bacteria,1MXIV@1224|Proteobacteria,1T10X@1236|Gammaproteobacteria,1X2MW@135613|Chromatiales 135613|Chromatiales O Type III secretion system lipoprotein chaperone (YscW) - - - - - - - - - - - - META,YscW TGS3_k127_717865_0 414684.RC1_0565 2.457e-302 938.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2TRDD@28211|Alphaproteobacteria,2JQ00@204441|Rhodospirillales 204441|Rhodospirillales H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C TGS3_k127_717865_7 314260.PB2503_08744 5.414e-21 96.0 COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S TGS3_k127_717865_6 402881.Plav_1046 2.559e-24 108.0 COG3609@1|root,COG3609@2|Bacteria,1N7IM@1224|Proteobacteria,2UF5D@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - ko:K07746 - - - - ko00000,ko02048 - - - ParD_antitoxin TGS3_k127_7214921_0 1134474.O59_000934 3.175e-106 357.0 COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,1S6C7@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Esterase PHB depolymerase lpqC - - ko:K03932 - - - - ko00000 - CE1 - Abhydrolase_2,Esterase_phd TGS3_k127_7214921_1 366602.Caul_1674 3.578e-38 162.0 COG0457@1|root,COG0457@2|Bacteria,1N06S@1224|Proteobacteria,2TQVV@28211|Alphaproteobacteria 28211|Alphaproteobacteria S MTH538 TIR-like domain (DUF1863) - - - - - - - - - - - - DUF1863,TPR_8 TGS3_k127_7221075_1 1089552.KI911559_gene2612 3.992e-137 447.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,2TQUR@28211|Alphaproteobacteria,2JPYE@204441|Rhodospirillales 204441|Rhodospirillales N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP TGS3_k127_7221075_0 1333998.M2A_2981 2.497e-188 599.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,4BPVZ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria T Sigma-54 interaction domain flbD - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat TGS3_k127_7221075_5 1081640.AGFU01000048_gene635 2.366e-27 114.0 COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,2UC6U@28211|Alphaproteobacteria,2K5NI@204457|Sphingomonadales 204457|Sphingomonadales N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation - - - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FliMN_C TGS3_k127_7221075_8 426117.M446_5124 0.0007289 49.0 COG1317@1|root,COG1317@2|Bacteria,1NSNC@1224|Proteobacteria,2TUID@28211|Alphaproteobacteria,1JSPZ@119045|Methylobacteriaceae 28211|Alphaproteobacteria N Flagellar assembly protein FliH fliH - - ko:K02411 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliH TGS3_k127_7221075_2 450851.PHZ_c0861 9.68e-103 344.0 COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,2TRIV@28211|Alphaproteobacteria,2KF0X@204458|Caulobacterales 204458|Caulobacterales N FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliG - - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N TGS3_k127_7221075_3 402881.Plav_2184 7.859e-85 301.0 COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,2TR6J@28211|Alphaproteobacteria,1JNW5@119043|Rhodobiaceae 28211|Alphaproteobacteria N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C TGS3_k127_7221075_4 663610.JQKO01000005_gene2488 1.642e-37 143.0 2AMHV@1|root,31CDG@2|Bacteria,1RGVA@1224|Proteobacteria,2U98Q@28211|Alphaproteobacteria,3NBDR@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1153) MA20_11245 - - - - - - - - - - - DUF1153 TGS3_k127_7221075_6 198467.NP92_06590 1.191e-24 114.0 COG4786@1|root,COG4786@2|Bacteria,1TRA2@1239|Firmicutes,4HBNB@91061|Bacilli,21XDH@150247|Anoxybacillus 91061|Bacilli N Flagellar basal body rod FlgEFG protein C-terminal flgG GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C TGS3_k127_7221075_7 1121033.AUCF01000016_gene5501 1.357e-07 57.0 COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,2UCHH@28211|Alphaproteobacteria,2JS6M@204441|Rhodospirillales 204441|Rhodospirillales N Required for flagellar hook formation. May act as a scaffolding protein - - - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FLgD_tudor,FlgD,FlgD_ig TGS3_k127_7226404_9 1090318.ATTI01000001_gene3369 1.685e-17 87.0 28YQN@1|root,2ZKI7@2|Bacteria,1NIIY@1224|Proteobacteria,2UM9B@28211|Alphaproteobacteria,2KBYB@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - TGS3_k127_7226404_4 1038860.AXAP01000027_gene1895 2.307e-114 379.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2TS3D@28211|Alphaproteobacteria,3JSBV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC - 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC TGS3_k127_7226404_1 1282876.BAOK01000001_gene3321 4.057e-191 616.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 TGS3_k127_7226404_8 1411685.U062_01903 4.897e-49 186.0 COG0760@1|root,COG0760@2|Bacteria,1PWUT@1224|Proteobacteria,1THKT@1236|Gammaproteobacteria,1JAGT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O PPIC-type PPIASE domain - - - - - - - - - - - - - TGS3_k127_7226404_6 1282876.BAOK01000001_gene3322 5.266e-63 228.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2TSX2@28211|Alphaproteobacteria,4BS3U@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 TGS3_k127_7226404_3 450851.PHZ_c1416 2.672e-134 441.0 COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2TS6U@28211|Alphaproteobacteria,2KG4F@204458|Caulobacterales 204458|Caulobacterales J Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family - - 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F TGS3_k127_7226404_7 1449350.OCH239_00610 8.666e-53 187.0 COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,2U9M1@28211|Alphaproteobacteria,4KNXC@93682|Roseivivax 28211|Alphaproteobacteria S Putative member of DMT superfamily (DUF486) - - - ko:K09922 - - - - ko00000 - - - DMT_6 TGS3_k127_7226404_0 1030157.AFMP01000019_gene625 2.253e-221 695.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2TQXC@28211|Alphaproteobacteria,2K0CG@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH,NMO TGS3_k127_7226404_10 228405.HNE_0142 2.184e-12 76.0 COG5513@1|root,COG5513@2|Bacteria 2|Bacteria G serine-type aminopeptidase activity - - - ko:K02030,ko:K14475 ko05143,map05143 M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - Inhibitor_I42 TGS3_k127_7226404_5 314260.PB2503_10954 5.946e-88 297.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2TSBW@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ - 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ TGS3_k127_7226404_2 366394.Smed_2575 5.726e-183 578.0 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TTYY@28211|Alphaproteobacteria,4B8SE@82115|Rhizobiaceae 28211|Alphaproteobacteria S alcohol dehydrogenase adh - - ko:K13979 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N TGS3_k127_7233333_1 366602.Caul_3399 8.116e-40 157.0 COG4783@1|root,COG4783@2|Bacteria,1QV70@1224|Proteobacteria,2TWBV@28211|Alphaproteobacteria 28211|Alphaproteobacteria S peptidase M48, Ste24p - - - - - - - - - - - - Peptidase_M48 TGS3_k127_7233333_0 1248917.ANFX01000011_gene167 4.146e-111 385.0 COG0457@1|root,COG0457@2|Bacteria,1N06S@1224|Proteobacteria,2TQVV@28211|Alphaproteobacteria,2K2KZ@204457|Sphingomonadales 204457|Sphingomonadales S MTH538 TIR-like domain (DUF1863) - - - - - - - - - - - - DUF1863 TGS3_k127_7242226_0 1207063.P24_03156 1.754e-96 330.0 COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2TRUC@28211|Alphaproteobacteria,2JQP6@204441|Rhodospirillales 204441|Rhodospirillales T COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc TGS3_k127_7242226_3 551275.KB899545_gene2728 2.355e-49 181.0 2ANVS@1|root,31DWA@2|Bacteria,1RKIA@1224|Proteobacteria,2UF8S@28211|Alphaproteobacteria,43XWD@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_7242226_1 420324.KI912069_gene6363 2.773e-73 260.0 COG0583@1|root,COG0583@2|Bacteria,1R51E@1224|Proteobacteria,2TZIK@28211|Alphaproteobacteria,1JXVG@119045|Methylobacteriaceae 28211|Alphaproteobacteria K PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate TGS3_k127_7242226_2 1380391.JIAS01000011_gene4709 5.866e-63 224.0 COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,2TR0R@28211|Alphaproteobacteria,2JR1G@204441|Rhodospirillales 204441|Rhodospirillales EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1 TGS3_k127_7244323_2 187303.BN69_2802 1.72e-73 252.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2TV1Q@28211|Alphaproteobacteria,36Y9I@31993|Methylocystaceae 28211|Alphaproteobacteria K Sir2 family cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 TGS3_k127_7244323_5 1030157.AFMP01000041_gene1231 1.883e-13 82.0 COG1426@1|root,COG1426@2|Bacteria,1MYWX@1224|Proteobacteria,2U8C2@28211|Alphaproteobacteria,2K4QD@204457|Sphingomonadales 204457|Sphingomonadales S Domain of unknown function (DUF4115) - - - - - - - - - - - - DUF4115,HTH_25 TGS3_k127_7244323_0 1247963.JPHU01000004_gene485 5.907e-147 476.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG2230 Cyclopropane fatty acid synthase and related methyltransferases cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS TGS3_k127_7244323_1 450851.PHZ_c0325 5.096e-127 412.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,2TVCS@28211|Alphaproteobacteria,2KF05@204458|Caulobacterales 204458|Caulobacterales S N-carbamoylputrescine amidase - - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase TGS3_k127_7244323_3 685035.ADAE01000024_gene1861 1.686e-55 206.0 COG3917@1|root,COG3917@2|Bacteria,1MV6E@1224|Proteobacteria,2TVJ4@28211|Alphaproteobacteria,2K0YH@204457|Sphingomonadales 204457|Sphingomonadales Q 2-hydroxychromene-2-carboxylate isomerase - - - - - - - - - - - - DSBA TGS3_k127_7244323_4 1123503.KB908056_gene1956 8.082e-22 98.0 COG1680@1|root,COG1680@2|Bacteria,1QD0J@1224|Proteobacteria,2U189@28211|Alphaproteobacteria,2KF70@204458|Caulobacterales 204458|Caulobacterales V PFAM Beta-lactamase - - - - - - - - - - - - Beta-lactamase TGS3_k127_7273770_0 394221.Mmar10_2846 1e-323 996.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2TQJA@28211|Alphaproteobacteria,43W58@69657|Hyphomonadaceae 28211|Alphaproteobacteria C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C TGS3_k127_7273770_4 1122214.AQWH01000001_gene604 3.594e-13 73.0 COG2142@1|root,COG2142@2|Bacteria,1MZND@1224|Proteobacteria,2VAE6@28211|Alphaproteobacteria,2PK2A@255475|Aurantimonadaceae 28211|Alphaproteobacteria C Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt TGS3_k127_7273770_3 314260.PB2503_04827 2.257e-29 122.0 COG2009@1|root,COG2009@2|Bacteria,1N02N@1224|Proteobacteria,2UC47@28211|Alphaproteobacteria 28211|Alphaproteobacteria C succinate dehydrogenase sdhC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt TGS3_k127_7273770_1 1247963.JPHU01000009_gene2337 4.222e-202 641.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2TQWH@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV TGS3_k127_7273770_5 1089551.KE386572_gene2221 1.7e-06 50.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2TTMG@28211|Alphaproteobacteria,4BQ5K@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15,2.7.6.3 ko:K00796,ko:K13941 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503 RC00002,RC00017,RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind TGS3_k127_7274504_1 1247963.JPHU01000002_gene2586 4.952e-68 244.0 COG0500@1|root,COG0500@2|Bacteria 2|Bacteria Q methyltransferase activity - - - ko:K04786,ko:K12240,ko:K13613,ko:K15677 ko01053,map01053 - - - ko00000,ko00001,ko01004,ko01008 - - - ADH_N,ADH_zinc_N,AMP-binding,Acyl_transf_1,Condensation,Glyoxalase_4,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,NUDIX,PP-binding,PS-DH,Thioesterase,ketoacyl-synt TGS3_k127_7274504_2 314260.PB2503_07769 5.555e-65 230.0 COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,2U7N2@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos TGS3_k127_7274504_0 631454.N177_2696 2.104e-108 361.0 COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,2TTC7@28211|Alphaproteobacteria,1JNQ1@119043|Rhodobiaceae 28211|Alphaproteobacteria M Polysaccharide biosynthesis protein galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase TGS3_k127_7274504_3 1262914.BN533_01308 9.531e-36 142.0 COG1212@1|root,COG1212@2|Bacteria,1TQU3@1239|Firmicutes,4H20C@909932|Negativicutes 909932|Negativicutes M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 TGS3_k127_7277737_4 1247963.JPHU01000003_gene1286 1.007e-38 150.0 COG1495@1|root,COG1495@2|Bacteria,1N89I@1224|Proteobacteria,2UE1Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria O bond formation protein, DsbB - - - - - - - - - - - - DsbB TGS3_k127_7277737_3 314260.PB2503_09324 6.336e-50 186.0 COG3932@1|root,COG3932@2|Bacteria,1MZD5@1224|Proteobacteria,2U9KP@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Exopolysaccharide synthesis, ExoD - - - - - - - - - - - - ExoD TGS3_k127_7277737_6 797114.C475_12115 0.0003863 53.0 COG3420@1|root,arCOG02519@2157|Archaea,2XTQ7@28890|Euryarchaeota,23TF0@183963|Halobacteria 183963|Halobacteria P Nitrous oxidase accessory protein nosD1 - - - - - - - - - - - Beta_helix,NosD,NosL TGS3_k127_7277737_2 314260.PB2503_09999 2.766e-85 299.0 COG0790@1|root,COG3409@1|root,COG0790@2|Bacteria,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - 3.2.1.132 ko:K01233,ko:K07126,ko:K13582 ko00520,ko01100,ko04112,map00520,map01100,map04112 - R02833 - ko00000,ko00001,ko01000 - - - Muraidase,PG_binding_1,Sel1 TGS3_k127_7277737_5 1247963.JPHU01000001_gene1753 1.089e-22 99.0 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria 1224|Proteobacteria O Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin tusA - - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA TGS3_k127_7277737_0 1502850.FG91_00802 8.086e-212 683.0 COG1629@1|root,COG4771@2|Bacteria,1QYDM@1224|Proteobacteria,2TXPM@28211|Alphaproteobacteria,2K1U8@204457|Sphingomonadales 204457|Sphingomonadales P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec TGS3_k127_7277737_1 1247963.JPHU01000004_gene606 6.949e-102 335.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria 28211|Alphaproteobacteria O COG0330 Membrane protease subunits stomatin prohibitin homologs - - - - - - - - - - - - Band_7 TGS3_k127_7281425_2 314260.PB2503_04622 2.014e-155 503.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2TS87@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 TGS3_k127_7281425_5 1123053.AUDG01000109_gene49 1.304e-53 196.0 2BCQC@1|root,326AQ@2|Bacteria,1RKFR@1224|Proteobacteria,1S7Q0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - - TGS3_k127_7281425_10 394221.Mmar10_0805 2.366e-12 74.0 COG4691@1|root,COG4691@2|Bacteria,1P84J@1224|Proteobacteria,2UYR3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Plasmid stability protein - - - ko:K21495 - - - - ko00000,ko02048 - - - - TGS3_k127_7281425_9 376733.IT41_17310 1.7e-21 100.0 COG4113@1|root,COG4113@2|Bacteria,1N7ET@1224|Proteobacteria,2UG7M@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - ko:K07065 - - - - ko00000 - - - PIN TGS3_k127_7281425_1 1247963.JPHU01000011_gene812 6.389e-160 516.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2TRN1@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K13038,ko:K21977 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein TGS3_k127_7281425_4 1202962.KB907157_gene3501 5.521e-79 280.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF TGS3_k127_7281425_11 1317118.ATO8_11594 0.0004649 49.0 COG1246@1|root,COG1246@2|Bacteria,1QZP2@1224|Proteobacteria,2TYAW@28211|Alphaproteobacteria,4KMTA@93682|Roseivivax 28211|Alphaproteobacteria E Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 TGS3_k127_7281425_7 479432.Sros_0410 2.496e-26 116.0 COG1396@1|root,COG1396@2|Bacteria,2IMV0@201174|Actinobacteria,4EK09@85012|Streptosporangiales 201174|Actinobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - Cupin_2,HTH_3,HTH_31 TGS3_k127_7281425_0 1123059.KB823012_gene2173 8.018e-221 696.0 COG0318@1|root,COG0318@2|Bacteria,1QVGC@1224|Proteobacteria,2TWFC@28211|Alphaproteobacteria,43WY7@69657|Hyphomonadaceae 28211|Alphaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - AMP-binding TGS3_k127_7281425_8 269084.syc0773_d 6.066e-22 102.0 COG3600@1|root,COG3600@2|Bacteria 2|Bacteria K Phage-associated protein gepA - - - - - - - - - - - DUF4065,MqsA_antitoxin TGS3_k127_7281425_6 331869.BAL199_28990 1.039e-38 147.0 COG2963@1|root,COG2963@2|Bacteria,1N1AA@1224|Proteobacteria,2UC5K@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Transposase - - - - - - - - - - - - HTH_Tnp_1 TGS3_k127_7281425_3 1168059.KB899087_gene1057 5.074e-148 473.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2TU72@28211|Alphaproteobacteria,3F0X8@335928|Xanthobacteraceae 28211|Alphaproteobacteria L HTH-like domain - - - - - - - - - - - - HTH_21,rve,rve_3 TGS3_k127_7306175_0 1333998.M2A_2461 2.058e-121 402.0 COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2TQRE@28211|Alphaproteobacteria,4BPHP@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase envZ - 2.7.13.3 ko:K07638 ko02020,ko02026,map02020,map02026 M00445,M00742,M00743 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA TGS3_k127_7306175_1 1247963.JPHU01000013_gene704 4.166e-78 267.0 COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TSQF@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain petR - - ko:K07659 ko02020,ko02026,map02020,map02026 M00445,M00742,M00743 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C TGS3_k127_7306175_2 1282876.BAOK01000001_gene1237 2.931e-17 86.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2TUI7@28211|Alphaproteobacteria,4BQGN@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA - 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf TGS3_k127_7325791_0 1247963.JPHU01000002_gene2754 0.0 1169.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Malic enzyme tme - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,PTA_PTB,malic TGS3_k127_7325791_1 1247963.JPHU01000002_gene2757 2.53e-72 250.0 COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria 28211|Alphaproteobacteria O COG0694 Thioredoxin-like proteins and domains - - - - - - - - - - - - Nfu_N,NifU TGS3_k127_7325791_2 1082933.MEA186_07904 3.29e-64 226.0 COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,2U7JU@28211|Alphaproteobacteria,43K20@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S NADPH-dependent FMN reductase - - - - - - - - - - - - Flavodoxin_2 TGS3_k127_7325791_3 1089552.KI911559_gene260 1.098e-20 93.0 COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,2U5B0@28211|Alphaproteobacteria,2JRTH@204441|Rhodospirillales 204441|Rhodospirillales C NADH dehydrogenase NAD(P)H nitroreductase rutE - - ko:K09019 ko00240,ko01100,map00240,map01100 - R09289 RC00087 ko00000,ko00001,ko01000 - - - Nitroreductase TGS3_k127_7335095_0 1121374.KB891585_gene1891 6.504e-148 491.0 COG1574@1|root,COG1574@2|Bacteria,1MXST@1224|Proteobacteria,1RS60@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 TGS3_k127_7335095_1 1265313.HRUBRA_02135 4.306e-76 269.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria,1J8CG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_19,TPR_8 TGS3_k127_734205_1 243365.CV_1764 4.763e-178 564.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VI77@28216|Betaproteobacteria,2KQQX@206351|Neisseriales 206351|Neisseriales I carboxylase - - 6.4.1.4 ko:K01969 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans TGS3_k127_734205_2 1280953.HOC_15832 5.206e-136 441.0 COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2U38D@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q taurine catabolism dioxygenase - - 1.14.11.17 ko:K03119 ko00430,ko00920,map00430,map00920 - R05320 RC01331 ko00000,ko00001,ko01000 - - - TauD TGS3_k127_734205_3 1395571.TMS3_0117510 1.645e-26 117.0 COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,1S60I@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Domain of unknown function DUF302 - - - - - - - - - - - - Beta-lactamase,DUF302 TGS3_k127_734205_4 715226.ABI_01230 2.798e-18 91.0 2EMIM@1|root,33F78@2|Bacteria,1NMJX@1224|Proteobacteria,2UKEZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_734205_0 228405.HNE_2039 8.367e-203 644.0 COG0793@1|root,COG0793@2|Bacteria,1MUA3@1224|Proteobacteria,2U1FI@28211|Alphaproteobacteria,43WMW@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Peptidase family S41 - - - - - - - - - - - - Peptidase_S41 TGS3_k127_7351157_1 667632.KB890176_gene4361 4.151e-131 425.0 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,2VHZZ@28216|Betaproteobacteria,1JZXD@119060|Burkholderiaceae 28216|Betaproteobacteria H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - BATS,Radical_SAM TGS3_k127_7351157_2 314260.PB2503_04747 3.655e-115 383.0 COG3540@1|root,COG3540@2|Bacteria,1R5RU@1224|Proteobacteria,2U4KZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG3540 Phosphodiesterase alkaline phosphatase D - - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD TGS3_k127_7351157_0 1280950.HJO_10727 3.125e-146 478.0 COG2234@1|root,COG2234@2|Bacteria,1NE83@1224|Proteobacteria,2TSF8@28211|Alphaproteobacteria,43W8R@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Peptidase M28 - - - - - - - - - - - - PA,Peptidase_M28 TGS3_k127_7351157_3 536019.Mesop_1854 2.403e-47 173.0 COG2940@1|root,COG2940@2|Bacteria,1N3VM@1224|Proteobacteria,2UDY0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG2940 Proteins containing SET domain - - - ko:K07117 - - - - ko00000 - - - SET TGS3_k127_7351157_4 450851.PHZ_c0155 2.825e-37 144.0 COG1670@1|root,COG1670@2|Bacteria,1RD77@1224|Proteobacteria,2U851@28211|Alphaproteobacteria,2KGNJ@204458|Caulobacterales 204458|Caulobacterales J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 TGS3_k127_7360144_2 450851.PHZ_c1866 3.641e-28 118.0 2CKCH@1|root,32RQY@2|Bacteria,1N0CS@1224|Proteobacteria,2UBS0@28211|Alphaproteobacteria,2KH6Q@204458|Caulobacterales 204458|Caulobacterales - - - - - - - - - - - - - - - TGS3_k127_7360144_1 1122137.AQXF01000005_gene989 1.291e-88 302.0 COG1446@1|root,COG1446@2|Bacteria,1RBN2@1224|Proteobacteria,2U6II@28211|Alphaproteobacteria 28211|Alphaproteobacteria E asparaginase - - 3.4.19.5 ko:K13051 - - - - ko00000,ko01000,ko01002 - - - Asparaginase_2 TGS3_k127_7360144_0 1280953.HOC_11148 3.967e-95 317.0 COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2TSQ0@28211|Alphaproteobacteria,43WIR@69657|Hyphomonadaceae 28211|Alphaproteobacteria G Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 TGS3_k127_7360144_3 1463825.JNXC01000045_gene3033 2.619e-27 122.0 COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4E53N@85010|Pseudonocardiales 201174|Actinobacteria K SCP-2 sterol transfer family - - - - - - - - - - - - Alkyl_sulf_C,HxlR,SCP2 TGS3_k127_7360144_4 582899.Hden_0883 4.801e-17 95.0 COG1075@1|root,COG1075@2|Bacteria,1P1TP@1224|Proteobacteria,2UVK2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - - TGS3_k127_7360144_5 1121033.AUCF01000023_gene23 3.443e-15 79.0 COG2207@1|root,COG2207@2|Bacteria,1R4RI@1224|Proteobacteria,2VE4S@28211|Alphaproteobacteria,2JU3V@204441|Rhodospirillales 204441|Rhodospirillales K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 TGS3_k127_7360581_2 237609.PSAKL28_23620 1.222e-21 105.0 COG3307@1|root,COG3307@2|Bacteria,1RCKR@1224|Proteobacteria,1SJKS@1236|Gammaproteobacteria 1236|Gammaproteobacteria M O-Antigen ligase - - - - - - - - - - - - Wzy_C TGS3_k127_7360581_0 1385935.N836_31000 2.409e-39 159.0 COG0457@1|root,COG0457@2|Bacteria,1G2CI@1117|Cyanobacteria,1HHY4@1150|Oscillatoriales 1117|Cyanobacteria S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1,Sulfotransfer_3 TGS3_k127_7360581_1 754476.Q7A_1412 1.765e-29 125.0 COG2244@1|root,COG2244@2|Bacteria,1MUMD@1224|Proteobacteria,1RS3A@1236|Gammaproteobacteria,461R5@72273|Thiotrichales 72273|Thiotrichales S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt_3 TGS3_k127_7362593_1 228405.HNE_2187 5.592e-119 398.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TSN8@28211|Alphaproteobacteria,43XU9@69657|Hyphomonadaceae 28211|Alphaproteobacteria M RND efflux system, outer membrane lipoprotein - - - - - - - - - - - - OEP TGS3_k127_7362593_0 1089551.KE386572_gene2337 0.0 1247.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,4BRPD@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria V AcrB/AcrD/AcrF family - - - ko:K03296,ko:K18902 - M00698 - - ko00000,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran TGS3_k127_7362593_2 557598.LHK_01426 8.977e-07 53.0 COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VINC@28216|Betaproteobacteria,2KPHI@206351|Neisseriales 28216|Betaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 TGS3_k127_7364662_0 224911.27350297 1.601e-195 618.0 COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,2TVIR@28211|Alphaproteobacteria,3JT6Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L hmm pf01609 - - - ko:K07481 - - - - ko00000 - - - DUF772 TGS3_k127_737026_3 450851.PHZ_c1627 2.128e-72 247.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria,2KG6J@204458|Caulobacterales 204458|Caulobacterales M Cyclopropane-fatty-acyl-phospholipid synthase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS TGS3_k127_737026_0 551275.KB899545_gene2668 3.137e-159 510.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TR4W@28211|Alphaproteobacteria,43WQ9@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Cysteine synthase cysB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP TGS3_k127_737026_2 1121124.JNIX01000007_gene596 5.902e-84 287.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2TR9R@28211|Alphaproteobacteria,2KFH2@204458|Caulobacterales 204458|Caulobacterales P Sulfurtransferase - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese TGS3_k127_737026_4 1177928.TH2_12852 3.427e-53 192.0 COG0454@1|root,COG0454@2|Bacteria,1RDGT@1224|Proteobacteria,2TRF5@28211|Alphaproteobacteria,2JSV9@204441|Rhodospirillales 204441|Rhodospirillales K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 TGS3_k127_737026_1 509190.Cseg_1905 1.74e-121 401.0 COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,2TS8Z@28211|Alphaproteobacteria,2KF9X@204458|Caulobacterales 204458|Caulobacterales E cystathionine beta-lyase - - 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP TGS3_k127_737026_7 1279017.AQYJ01000026_gene22 1.225e-06 51.0 2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_737026_5 314260.PB2503_01427 1.798e-35 138.0 2C7TH@1|root,32RJS@2|Bacteria,1MZK8@1224|Proteobacteria,2UC2R@28211|Alphaproteobacteria 28211|Alphaproteobacteria S ETC complex I subunit MA20_30235 - 1.6.5.3 ko:K00329 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - ETC_C1_NDUFA4 TGS3_k127_7383855_11 1121124.JNIX01000015_gene1975 1.496e-54 194.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria,2KGBZ@204458|Caulobacterales 204458|Caulobacterales J Ribosomal protein L17 rplQ - - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 TGS3_k127_7383855_1 1247963.JPHU01000003_gene1239 1.344e-184 580.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2TSI0@28211|Alphaproteobacteria 28211|Alphaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L TGS3_k127_7383855_8 1502851.FG93_03811 7.639e-61 212.0 COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2U717@28211|Alphaproteobacteria,3JY0A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 TGS3_k127_7383855_7 314254.OA2633_03556 5.797e-64 220.0 COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2U73D@28211|Alphaproteobacteria,43XSJ@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 TGS3_k127_7383855_5 314260.PB2503_09549 2e-65 229.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2TT6A@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid TGS3_k127_7383855_0 1247963.JPHU01000003_gene1243 1.43e-210 662.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2TQMT@28211|Alphaproteobacteria 28211|Alphaproteobacteria U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY TGS3_k127_7383855_10 1282876.BAOK01000001_gene1739 8.401e-55 198.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2U79D@28211|Alphaproteobacteria,4BQEC@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria J binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A TGS3_k127_7383855_19 1121946.AUAX01000046_gene7476 3.436e-15 78.0 COG4290@1|root,COG4290@2|Bacteria,2IM71@201174|Actinobacteria,4DE18@85008|Micromonosporales 201174|Actinobacteria F ribonuclease - - - - - - - - - - - - Ribonuclease TGS3_k127_7383855_16 1121948.AUAC01000003_gene2464 8.515e-23 98.0 COG1841@1|root,COG1841@2|Bacteria,1PU2S@1224|Proteobacteria,2UF55@28211|Alphaproteobacteria,43YG5@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Ribosomal protein L30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 TGS3_k127_7383855_3 314260.PB2503_09524 6.517e-85 286.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2TSRI@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C TGS3_k127_7383855_12 266834.SMc01293 1.513e-40 153.0 COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2U9A6@28211|Alphaproteobacteria,4BEQD@82115|Rhizobiaceae 28211|Alphaproteobacteria J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p TGS3_k127_7383855_4 1122137.AQXF01000006_gene961 8.084e-72 252.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2TV09@28211|Alphaproteobacteria 28211|Alphaproteobacteria J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 TGS3_k127_7383855_9 450851.PHZ_c1244 7.485e-55 197.0 COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2U6ZH@28211|Alphaproteobacteria,2KGMA@204458|Caulobacterales 204458|Caulobacterales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH - - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 TGS3_k127_7383855_13 639283.Snov_1461 2.283e-39 148.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,2UC01@28211|Alphaproteobacteria,3EZMZ@335928|Xanthobacteraceae 28211|Alphaproteobacteria J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 TGS3_k127_7383855_2 314260.PB2503_09499 9.292e-86 286.0 COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2TQPF@28211|Alphaproteobacteria 28211|Alphaproteobacteria J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C TGS3_k127_7383855_14 316055.RPE_3575 5.207e-34 140.0 COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2UC6Y@28211|Alphaproteobacteria,3JZDP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 TGS3_k127_7383855_6 314260.PB2503_09489 4.418e-65 224.0 COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,2U743@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 TGS3_k127_7383855_15 394221.Mmar10_1786 5.807e-30 120.0 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2UBRF@28211|Alphaproteobacteria,43Y48@69657|Hyphomonadaceae 28211|Alphaproteobacteria J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 TGS3_k127_7383855_17 1509405.GV67_23880 1.751e-20 92.0 COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2UF59@28211|Alphaproteobacteria,4BG2B@82115|Rhizobiaceae 28211|Alphaproteobacteria J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 TGS3_k127_7383855_18 582402.Hbal_2076 2.002e-15 76.0 COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2U710@28211|Alphaproteobacteria,43XNF@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 TGS3_k127_7386967_3 1282361.ABAC402_12715 9.157e-12 67.0 2EV7A@1|root,33NN1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - TGS3_k127_7386967_0 1121949.AQXT01000002_gene2374 3.716e-42 162.0 COG0705@1|root,COG0705@2|Bacteria,1RB4A@1224|Proteobacteria,2UMT7@28211|Alphaproteobacteria,43XVY@69657|Hyphomonadaceae 28211|Alphaproteobacteria S membrane protein (homolog of Drosophila rhomboid) - - - - - - - - - - - - Rhomboid TGS3_k127_7386967_1 573065.Astex_1081 4.836e-28 117.0 COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,2UF6U@28211|Alphaproteobacteria,2KH96@204458|Caulobacterales 204458|Caulobacterales T Belongs to the BolA IbaG family - - - ko:K05527 - - - - ko00000,ko03000 - - - BolA TGS3_k127_7386967_2 314260.PB2503_00882 7.117e-28 123.0 COG2214@1|root,COG2214@2|Bacteria,1MXTG@1224|Proteobacteria,2TRZH@28211|Alphaproteobacteria 28211|Alphaproteobacteria O molecular chaperone - - - - - - - - - - - - DnaJ TGS3_k127_7391868_10 1105367.CG50_05195 6.651e-36 139.0 2CCMQ@1|root,32RW3@2|Bacteria,1MZHB@1224|Proteobacteria,2UCC9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2794) MA20_43795 - - - - - - - - - - - DUF2794 TGS3_k127_7391868_8 1247963.JPHU01000001_gene1869 2.576e-53 194.0 COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,2U7GI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH - - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX TGS3_k127_7391868_6 1247963.JPHU01000001_gene1868 8.427e-56 211.0 COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,2TUFD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - ko:K09798 - - - - ko00000 - - - Polysacc_deac_2 TGS3_k127_7391868_0 1247963.JPHU01000007_gene1670 2.885e-165 532.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 TGS3_k127_7391868_7 314260.PB2503_05157 5.015e-54 207.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2TUSP@28211|Alphaproteobacteria 28211|Alphaproteobacteria D COG4942 Membrane-bound metallopeptidase filA - - - - - - - - - - - Peptidase_M23 TGS3_k127_7391868_9 1247963.JPHU01000007_gene1667 7.964e-40 153.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2UBSV@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS TGS3_k127_7391868_11 1411123.JQNH01000001_gene3899 5.333e-27 116.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2U6ZC@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like TGS3_k127_7391868_12 1123059.KB823012_gene2324 1.132e-12 72.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2U6ZC@28211|Alphaproteobacteria,43XMW@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like TGS3_k127_7391868_1 1247963.JPHU01000009_gene2399 4.28e-151 484.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2TR5I@28211|Alphaproteobacteria 28211|Alphaproteobacteria S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 TGS3_k127_7391868_2 1137799.GZ78_16435 1.181e-144 473.0 COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RRXR@1236|Gammaproteobacteria,1XQ2D@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 TGS3_k127_7391868_3 318996.AXAZ01000001_gene4608 3.572e-125 413.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2TT2F@28211|Alphaproteobacteria,3JX03@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C NADH:flavin oxidoreductase / NADH oxidase family - - 1.14.13.40 ko:K09461 ko00627,ko01120,map00627,map01120 - R03998,R03999 RC00244 ko00000,ko00001,ko01000 - - - Oxidored_FMN TGS3_k127_7391868_4 1169143.KB911039_gene4449 1.623e-73 254.0 COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,2VH95@28216|Betaproteobacteria,1K5ZQ@119060|Burkholderiaceae 28216|Betaproteobacteria O Belongs to the GST superfamily gstA - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_3,GST_N,GST_N_3 TGS3_k127_7391868_5 1247963.JPHU01000009_gene2361 2.626e-60 221.0 COG5010@1|root,COG5010@2|Bacteria,1MVTK@1224|Proteobacteria,2TVBA@28211|Alphaproteobacteria 28211|Alphaproteobacteria U COG0457 FOG TPR repeat MA20_18455 - - - - - - - - - - - TPR_10,TPR_12,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8 TGS3_k127_7391868_14 402881.Plav_0242 6.325e-05 49.0 COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,2TSI6@28211|Alphaproteobacteria,1JN1W@119043|Rhodobiaceae 28211|Alphaproteobacteria E Cytosol aminopeptidase family, catalytic domain pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17 TGS3_k127_7393938_0 1122970.AUHC01000005_gene2018 8.998e-299 930.0 COG0365@1|root,COG0604@1|root,COG1024@1|root,COG0365@2|Bacteria,COG0604@2|Bacteria,COG1024@2|Bacteria,1MXIK@1224|Proteobacteria,2U43I@28211|Alphaproteobacteria,2K2UF@204457|Sphingomonadales 204457|Sphingomonadales CI Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ADH_zinc_N,AMP-binding,AMP-binding_C,ECH_1 TGS3_k127_7395669_1 1161401.ASJA01000025_gene231 5.843e-69 243.0 COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,2TRTM@28211|Alphaproteobacteria,43XPV@69657|Hyphomonadaceae 28211|Alphaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family nagK - 3.7.1.20 ko:K16165 ko00350,ko01100,ko01120,map00350,map01100,map01120 - R01085 RC00326,RC00446 ko00000,ko00001,ko01000 - - - FAA_hydrolase TGS3_k127_7395669_2 347834.RHE_CH03309 1.983e-33 136.0 COG3813@1|root,COG3813@2|Bacteria,1N712@1224|Proteobacteria,2UFME@28211|Alphaproteobacteria,4BG6B@82115|Rhizobiaceae 28211|Alphaproteobacteria S protein conserved in bacteria MA20_39405 - - ko:K09984 - - - - ko00000 - - - DUF1272 TGS3_k127_7395669_0 1247963.JPHU01000002_gene2733 8.018e-143 480.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria 28211|Alphaproteobacteria M mechanosensitive ion channel kefA - - ko:K05802 - - - - ko00000,ko02000 1.A.23.1.1 - - DUF3772,MS_channel TGS3_k127_7419954_2 1122613.ATUP01000002_gene2640 6.439e-47 179.0 COG2267@1|root,COG2267@2|Bacteria,1N8UK@1224|Proteobacteria,2U35V@28211|Alphaproteobacteria,440WP@69657|Hyphomonadaceae 28211|Alphaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_6 TGS3_k127_7419954_3 314260.PB2503_09839 2.11e-40 156.0 COG0847@1|root,COG0847@2|Bacteria,1RHD8@1224|Proteobacteria,2UKPY@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - - TGS3_k127_7419954_0 1333998.M2A_1557 8.425e-103 345.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2TSDZ@28211|Alphaproteobacteria,4BPY2@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the FPP GGPP synthase family ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt TGS3_k127_7419954_4 913325.N799_00200 9.102e-36 150.0 COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,1RNAP@1236|Gammaproteobacteria,1X4RV@135614|Xanthomonadales 135614|Xanthomonadales M UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase rfb303 - - - - - - - - - - - Glycos_transf_4 TGS3_k127_7419954_1 1150626.PHAMO_300011 6.302e-58 213.0 COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2TUFV@28211|Alphaproteobacteria,2JRVD@204441|Rhodospirillales 204441|Rhodospirillales I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE - 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N TGS3_k127_7421931_0 1247963.JPHU01000001_gene2061 3.531e-160 518.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria 28211|Alphaproteobacteria S amidohydrolase - - - - - - - - - - - - M20_dimer,Peptidase_M20 TGS3_k127_7421931_1 411684.HPDFL43_15462 2.945e-54 193.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,43HDI@69277|Phyllobacteriaceae 28211|Alphaproteobacteria V lipid A ABC exporter family, fused ATPase and inner membrane subunits msbA2 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran TGS3_k127_742533_7 1535287.JP74_22190 1.186e-121 397.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TR2P@28211|Alphaproteobacteria,3N9IX@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria V AAA domain, putative AbiEii toxin, Type IV TA system MA20_09455 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran TGS3_k127_742533_5 1161401.ASJA01000003_gene2956 1.49e-127 419.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,2TU59@28211|Alphaproteobacteria 28211|Alphaproteobacteria V COG0842 ABC-type multidrug transport system, permease component MA20_09460 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 TGS3_k127_742533_4 1247963.JPHU01000014_gene985 1.002e-156 502.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member recD - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2 TGS3_k127_742533_14 1123059.KB823011_gene1542 5.706e-45 188.0 COG0457@1|root,COG0457@2|Bacteria,1N9AG@1224|Proteobacteria,2UCGH@28211|Alphaproteobacteria,43XNA@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF3137) - - - - - - - - - - - - DUF3137 TGS3_k127_742533_1 1247963.JPHU01000004_gene464 8.847e-211 709.0 COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase barA_3 - 2.7.13.1 ko:K05962 - - - - ko00000,ko01000 - - - CHASE,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_7,PAS_9,Response_reg TGS3_k127_742533_2 1280944.HY17_07370 1.653e-204 653.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2UQAG@28211|Alphaproteobacteria,43WBH@69657|Hyphomonadaceae 28211|Alphaproteobacteria V ABC transporter atm1 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran TGS3_k127_742533_6 1121948.AUAC01000004_gene114 2.096e-124 405.0 COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,2UVAZ@28211|Alphaproteobacteria,43WKM@69657|Hyphomonadaceae 28211|Alphaproteobacteria I 3-hydroxyisobutyrate dehydrogenase mmsB - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 TGS3_k127_742533_9 1487953.JMKF01000045_gene2785 5.715e-65 237.0 COG0438@1|root,COG0438@2|Bacteria,1G1G7@1117|Cyanobacteria,1H9X4@1150|Oscillatoriales 1117|Cyanobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 TGS3_k127_742533_15 1429916.X566_05055 2.351e-40 157.0 COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2U5GF@28211|Alphaproteobacteria,3JWEW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Glutathione S-transferase MA20_19220 - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N_3 TGS3_k127_742533_8 1333998.M2A_0624 8.23e-103 346.0 COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,2TQW3@28211|Alphaproteobacteria,4BPY9@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria I Enoyl-CoA hydratase/isomerase hibch - 3.1.2.4,4.2.1.17 ko:K01692,ko:K05605 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212 M00013,M00032,M00087 R03026,R03045,R03158,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05064,R05595,R06411,R06412,R06942,R08093 RC00004,RC00014,RC00137,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_2 TGS3_k127_742533_10 745310.G432_04900 1.414e-62 228.0 COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,2TRH2@28211|Alphaproteobacteria,2K99V@204457|Sphingomonadales 204457|Sphingomonadales C Prolyl 4-hydroxylase alpha subunit homologues. - - - ko:K07336 - - - - ko00000,ko01000 - - - 2OG-FeII_Oxy_3 TGS3_k127_742533_12 745310.G432_04905 2.868e-47 183.0 2DWG9@1|root,34073@2|Bacteria,1NVA6@1224|Proteobacteria,2URJH@28211|Alphaproteobacteria,2K8JR@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - TGS3_k127_742533_3 551275.KB899544_gene1849 1.226e-197 620.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,43W6Z@69657|Hyphomonadaceae 28211|Alphaproteobacteria I COG1960 Acyl-CoA dehydrogenases MA20_27425 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N TGS3_k127_742533_16 582402.Hbal_1389 2.362e-37 151.0 COG0586@1|root,COG0586@2|Bacteria,1Q9R4@1224|Proteobacteria,2V4F9@28211|Alphaproteobacteria,4409I@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Pfam SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc TGS3_k127_742533_13 1122135.KB893134_gene3269 2.794e-46 173.0 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,2UC7G@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA TGS3_k127_742533_11 114615.BRADO3442 7.771e-58 207.0 COG3253@1|root,COG3253@2|Bacteria,1MVBM@1224|Proteobacteria,2TU49@28211|Alphaproteobacteria,3JSGJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Chlorite dismutase - - - - - - - - - - - - Chlor_dismutase TGS3_k127_742533_0 551275.KB899544_gene1847 1.166e-268 833.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2TSMD@28211|Alphaproteobacteria,43WNH@69657|Hyphomonadaceae 28211|Alphaproteobacteria C COG1012 NAD-dependent aldehyde dehydrogenases mmsA GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh TGS3_k127_742533_17 367336.OM2255_05895 8.057e-35 134.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TUMJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E aminotransferase class V - - - - - - - - - - - - Aminotran_5 TGS3_k127_7430033_2 1247963.JPHU01000003_gene1335 2.931e-45 166.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2TRX2@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 TGS3_k127_7430033_1 1247963.JPHU01000003_gene1334 5.784e-70 255.0 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2U0K2@28211|Alphaproteobacteria 28211|Alphaproteobacteria M N-acetylmuramoyl-L-alanine amidase amiC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3 TGS3_k127_7430033_0 314260.PB2503_12979 3.326e-318 994.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2USBB@28211|Alphaproteobacteria 28211|Alphaproteobacteria M penicillin-binding protein mrcA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase TGS3_k127_7430033_3 1123267.JONN01000001_gene459 2.742e-15 78.0 COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2TR9V@28211|Alphaproteobacteria,2K0B2@204457|Sphingomonadales 204457|Sphingomonadales J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 TGS3_k127_7435902_2 1282876.BAOK01000001_gene3467 7.507e-48 182.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TSTS@28211|Alphaproteobacteria,4BPXA@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P PFAM Binding-protein-dependent transport system inner membrane component sfuB - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 TGS3_k127_7435902_1 402881.Plav_0178 1.139e-75 267.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,1JNSN@119043|Rhodobiaceae 28211|Alphaproteobacteria E ABC transporter fbpC - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 TGS3_k127_7435902_0 1122970.AUHC01000004_gene2289 4.422e-117 387.0 COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2TR6P@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type Fe3 transport system, periplasmic component futA1 - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 TGS3_k127_7435902_3 1470591.BW41_00664 3.037e-43 172.0 COG3751@1|root,COG3751@2|Bacteria,1NG7K@1224|Proteobacteria,2UGEJ@28211|Alphaproteobacteria,2K33W@204457|Sphingomonadales 204457|Sphingomonadales O Prolyl 4-hydroxylase alpha subunit homologues. - - 1.14.11.2 ko:K00472 ko00330,ko01100,map00330,map01100 - R01252 RC00478 ko00000,ko00001,ko01000 - - - 2OG-FeII_Oxy_3 TGS3_k127_7435902_4 1247963.JPHU01000003_gene1517 3.915e-32 131.0 COG0735@1|root,COG0735@2|Bacteria 2|Bacteria P belongs to the Fur family furB GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02076,ko:K03711,ko:K09823 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - FUR TGS3_k127_7437908_0 1082933.MEA186_07989 1.75e-216 689.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,43IK9@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P Cation transporter/ATPase, N-terminus - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase TGS3_k127_7466101_7 46429.BV95_00523 3.047e-10 69.0 COG4970@1|root,COG4970@2|Bacteria,1N9H1@1224|Proteobacteria,2UGK7@28211|Alphaproteobacteria,2K5CF@204457|Sphingomonadales 204457|Sphingomonadales NU general secretion pathway protein gspH - - ko:K02457 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspH,N_methyl TGS3_k127_7466101_4 316273.XCV0759 1.05e-46 173.0 COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1X6M4@135614|Xanthomonadales 135614|Xanthomonadales U General secretion pathway protein xcsG - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG TGS3_k127_7466101_3 1247963.JPHU01000001_gene2144 1.211e-114 382.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2TV76@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU General secretion pathway protein F gspF - - ko:K02455,ko:K02653 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSF TGS3_k127_7466101_1 1247963.JPHU01000001_gene2145 1.609e-216 681.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2TRMU@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N TGS3_k127_7466101_2 1030157.AFMP01000052_gene174 1.546e-147 491.0 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,2TT8A@28211|Alphaproteobacteria,2K22S@204457|Sphingomonadales 204457|Sphingomonadales NU Type II secretion system protein D gspD - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N TGS3_k127_7466101_6 1537715.JQFJ01000005_gene222 2.207e-12 78.0 COG3031@1|root,COG3031@2|Bacteria,1RFDB@1224|Proteobacteria,2U64N@28211|Alphaproteobacteria,2K0SG@204457|Sphingomonadales 204457|Sphingomonadales U Type II secretory pathway component PulC - - - ko:K02452 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - PDZ_2,T2SSC TGS3_k127_7466101_0 1280949.HAD_14219 0.0 1046.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MX4K@1224|Proteobacteria,2TV3K@28211|Alphaproteobacteria,43WQY@69657|Hyphomonadaceae 28211|Alphaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec TGS3_k127_7466101_5 1122613.ATUP01000001_gene1780 2.751e-15 75.0 COG2182@1|root,COG2182@2|Bacteria,1MU3H@1224|Proteobacteria,2U0ZI@28211|Alphaproteobacteria,43WPN@69657|Hyphomonadaceae 28211|Alphaproteobacteria G Parallel beta-helix repeats - - - - - - - - - - - - - TGS3_k127_7470748_8 402881.Plav_2581 3.263e-24 104.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2TS8J@28211|Alphaproteobacteria,1JNU0@119043|Rhodobiaceae 28211|Alphaproteobacteria J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - - ko:K02533 - - - - ko00000,ko01000,ko03016 - - - DUF559,SpoU_methylase TGS3_k127_7470748_5 1280941.HY2_15035 2.244e-42 160.0 COG1742@1|root,COG1742@2|Bacteria,1MZI8@1224|Proteobacteria,2UBWY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S UPF0060 membrane protein - - - ko:K09771 - - - - ko00000,ko02000 2.A.7.26 - - UPF0060 TGS3_k127_7470748_3 1035191.HMPREF0185_01621 2.138e-194 617.0 COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,2TS7A@28211|Alphaproteobacteria,2KG2S@204458|Caulobacterales 204458|Caulobacterales Q dioxygenase - - - ko:K11159 - - - - ko00000 - - - RPE65 TGS3_k127_7470748_1 1247963.JPHU01000001_gene1865 2.338e-199 631.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2TS6F@28211|Alphaproteobacteria 28211|Alphaproteobacteria O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI TGS3_k127_7470748_9 1247963.JPHU01000001_gene1954 7.786e-11 71.0 COG1286@1|root,COG1286@2|Bacteria,1RJE1@1224|Proteobacteria 1224|Proteobacteria S Pfam Colicin V production protein cvpA - - ko:K03558 - - - - ko00000 - - - Colicin_V TGS3_k127_7470748_0 1247963.JPHU01000001_gene1955 1.363e-212 671.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2TR8V@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,GATase_7,Pribosyltran TGS3_k127_7470748_7 1411123.JQNH01000001_gene1064 1.389e-38 157.0 COG2050@1|root,COG2050@2|Bacteria,1MZRJ@1224|Proteobacteria,2U9BM@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q protein possibly involved in aromatic compounds catabolism MA20_36950 - - - - - - - - - - - 4HBT TGS3_k127_7470748_2 366602.Caul_4144 3.436e-198 635.0 COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2TS4N@28211|Alphaproteobacteria,2KFC6@204458|Caulobacterales 204458|Caulobacterales H cobalt chelatase - - 6.6.1.2 ko:K09883 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - CobT,CobT_C TGS3_k127_7470748_6 1121861.KB899915_gene1920 1.148e-39 157.0 2DR3T@1|root,33A1M@2|Bacteria,1QZB5@1224|Proteobacteria,2UMK0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_7470748_4 317655.Sala_0372 6.043e-129 429.0 COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2TQY4@28211|Alphaproteobacteria,2K117@204457|Sphingomonadales 204457|Sphingomonadales E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 TGS3_k127_7501819_1 1123393.KB891326_gene25 5.771e-14 79.0 COG1487@1|root,COG1487@2|Bacteria,1MZQC@1224|Proteobacteria,2WADV@28216|Betaproteobacteria,1KTH6@119069|Hydrogenophilales 119069|Hydrogenophilales S PIN domain - - - - - - - - - - - - PIN TGS3_k127_7501819_0 1247963.JPHU01000002_gene2628 2.396e-310 972.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,2TQV8@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind TGS3_k127_7525749_0 1150469.RSPPHO_03251 1.166e-147 475.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,2JR3C@204441|Rhodospirillales 204441|Rhodospirillales M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46,4.2.1.76 ko:K01710,ko:K12450 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 M00793 R00293,R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd TGS3_k127_7525749_1 1121405.dsmv_2095 3.457e-47 181.0 COG1597@1|root,COG1597@2|Bacteria,1RB97@1224|Proteobacteria 1224|Proteobacteria I lipid kinase activity - - - - - - - - - - - - Mmp37 TGS3_k127_7525749_2 1120792.JAFV01000001_gene2594 2.315e-31 135.0 COG1597@1|root,COG1597@2|Bacteria,1RIZ6@1224|Proteobacteria,2U9FH@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Diacylglycerol kinase catalytic domain - - - - - - - - - - - - DAGK_cat TGS3_k127_7525749_3 338966.Ppro_2745 1.227e-22 101.0 COG1409@1|root,COG1409@2|Bacteria,1MXD6@1224|Proteobacteria,42SIA@68525|delta/epsilon subdivisions,2X5AU@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos TGS3_k127_7536195_1 59538.XP_005974715.1 1.359e-16 84.0 COG0657@1|root,KOG1515@2759|Eukaryota,38HRI@33154|Opisthokonta,3C0T1@33208|Metazoa,3DGQQ@33213|Bilateria 33208|Metazoa V AB hydrolase superfamily protein C1039.03-like - - - - - - - - - - - - Abhydrolase_3 TGS3_k127_7536195_0 1247963.JPHU01000012_gene931 1.242e-173 563.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_8 TGS3_k127_7536195_2 314260.PB2503_02857 1.121e-09 63.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2TR1R@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 TGS3_k127_7557027_5 1346791.M529_19880 0.0001078 53.0 COG2771@1|root,COG2771@2|Bacteria,1RBMH@1224|Proteobacteria,2U67B@28211|Alphaproteobacteria,2K1GA@204457|Sphingomonadales 204457|Sphingomonadales K helix_turn_helix, Lux Regulon - - - - - - - - - - - - - TGS3_k127_7557027_4 446462.Amir_2371 3.437e-11 74.0 COG3437@1|root,COG3437@2|Bacteria,2IKC2@201174|Actinobacteria 201174|Actinobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg TGS3_k127_7557027_0 247634.GPB2148_3441 4.623e-57 220.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RWS2@1236|Gammaproteobacteria,1JA5T@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF,HATPase_c TGS3_k127_7557027_3 290317.Cpha266_1786 8.694e-19 91.0 COG0745@1|root,COG0745@2|Bacteria,1FFE8@1090|Chlorobi 1090|Chlorobi T PFAM response regulator receiver - - - - - - - - - - - - Response_reg TGS3_k127_7557027_2 1210884.HG799462_gene9086 9.949e-25 119.0 COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes 203682|Planctomycetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg TGS3_k127_7557027_1 118166.JH976538_gene5059 7.471e-56 214.0 COG4191@1|root,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria,1HA9K@1150|Oscillatoriales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg TGS3_k127_7577462_3 1282876.BAOK01000001_gene2800 4.203e-71 250.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,2TUNX@28211|Alphaproteobacteria,4BQ18@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC - 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 TGS3_k127_7577462_0 314260.PB2503_06492 3.574e-144 467.0 COG2951@1|root,COG3409@1|root,COG2951@2|Bacteria,COG3409@2|Bacteria,1MUZ3@1224|Proteobacteria,2TRP0@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Lytic murein transglycosylase mltB - - ko:K00786,ko:K08305 - - - - ko00000,ko01000,ko01011 - GH103 - PG_binding_1,SLT_2 TGS3_k127_7577462_4 685035.ADAE01000002_gene2371 1.565e-69 248.0 COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,2K4E9@204457|Sphingomonadales 204457|Sphingomonadales E COG0346 Lactoylglutathione lyase and related lyases gloA - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase TGS3_k127_7577462_6 1247963.JPHU01000002_gene2572 1.491e-46 184.0 COG5488@1|root,COG5488@2|Bacteria,1NPQQ@1224|Proteobacteria,2UB81@28211|Alphaproteobacteria 28211|Alphaproteobacteria S integral membrane protein - - - - - - - - - - - - DUF2244 TGS3_k127_7577462_1 1415779.JOMH01000001_gene2865 3.764e-84 286.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,1X340@135614|Xanthomonadales 135614|Xanthomonadales L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD TGS3_k127_7577462_2 1247963.JPHU01000002_gene2569 2.612e-72 254.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2TTB3@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase TGS3_k127_7577462_5 1282876.BAOK01000001_gene3335 1.452e-63 228.0 COG0398@1|root,COG0398@2|Bacteria,1RBAE@1224|Proteobacteria,2U6B6@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function, DUF547 - - - - - - - - - - - - DUF547 TGS3_k127_761331_2 1120956.JHZK01000001_gene3213 1.82e-75 259.0 COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,2TTQS@28211|Alphaproteobacteria,1JN09@119043|Rhodobiaceae 28211|Alphaproteobacteria IQ KR domain MA20_27940 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - - - - - - - - - - adh_short TGS3_k127_761331_1 1382303.JPOM01000001_gene2005 1.86e-107 357.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,2KFQ3@204458|Caulobacterales 204458|Caulobacterales S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C TGS3_k127_761331_4 1278073.MYSTI_00842 1.282e-17 91.0 COG1309@1|root,COG1309@2|Bacteria,1RG6C@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator, TetR family - - - - - - - - - - - - TetR_C_6,TetR_N TGS3_k127_761331_0 1247963.JPHU01000012_gene935 3.928e-212 672.0 COG1206@1|root,COG1206@2|Bacteria,1MWNQ@1224|Proteobacteria,2TR6M@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA TGS3_k127_761331_3 702113.PP1Y_AT36671 3.624e-34 133.0 COG0286@1|root,COG0286@2|Bacteria,1MWUJ@1224|Proteobacteria,2TT41@28211|Alphaproteobacteria,2K4MP@204457|Sphingomonadales 204457|Sphingomonadales V InterPro DEAD DEAH box helicase - - - - - - - - - - - - N6_Mtase TGS3_k127_766531_4 269796.Rru_A0724 4.459e-65 228.0 COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2TUX0@28211|Alphaproteobacteria,2JRSA@204441|Rhodospirillales 204441|Rhodospirillales S Protein of unknown function (DUF1365) - - - ko:K09701 - - - - ko00000 - - - DUF1365 TGS3_k127_766531_5 685778.AORL01000025_gene83 4.551e-37 153.0 2ASJY@1|root,31I0J@2|Bacteria,1N0AE@1224|Proteobacteria,2UCJQ@28211|Alphaproteobacteria,2K162@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - TGS3_k127_766531_1 1161401.ASJA01000009_gene1729 2.63e-128 414.0 COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2TTE6@28211|Alphaproteobacteria,43W92@69657|Hyphomonadaceae 28211|Alphaproteobacteria I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit scoA - 2.8.3.5 ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans TGS3_k127_766531_2 1122137.AQXF01000005_gene1154 2.652e-106 348.0 COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,2TQS5@28211|Alphaproteobacteria 28211|Alphaproteobacteria I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit scoB - 2.8.3.5 ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans TGS3_k127_766531_3 1430440.MGMSRv2_1706 3.241e-76 264.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2TSUR@28211|Alphaproteobacteria,2JPZY@204441|Rhodospirillales 204441|Rhodospirillales V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA TGS3_k127_766531_6 1038858.AXBA01000001_gene3122 3.297e-28 123.0 COG3932@1|root,COG3932@2|Bacteria,1RF82@1224|Proteobacteria,2VGVX@28211|Alphaproteobacteria,3F2CP@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Exopolysaccharide synthesis, ExoD - - - - - - - - - - - - ExoD TGS3_k127_766531_0 392499.Swit_1948 7.641e-202 638.0 COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TRAP@28211|Alphaproteobacteria,2K0IY@204457|Sphingomonadales 204457|Sphingomonadales EGP Major Facilitator - - - - - - - - - - - - Sugar_tr TGS3_k127_799596_0 1280950.HJO_00770 1.143e-91 324.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43XNB@69657|Hyphomonadaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - TIR_2,TPR_16,TPR_8,Trans_reg_C TGS3_k127_799596_1 1120953.AUBH01000009_gene47 1.142e-13 80.0 2ECN7@1|root,336K3@2|Bacteria,1NV01@1224|Proteobacteria,1SRBC@1236|Gammaproteobacteria,46BJK@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_813333_3 582899.Hden_1429 1.119e-61 220.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TRX9@28211|Alphaproteobacteria 28211|Alphaproteobacteria E oxidoreductase - - - ko:K09471 ko00330,ko01100,map00330,map01100 M00136 R07415 RC00062 ko00000,ko00001,ko00002,ko01000 - - - DAO TGS3_k127_813333_2 290398.Csal_1181 1.092e-124 413.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,1XHZD@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the glutamine synthetase family - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C TGS3_k127_813333_0 1122137.AQXF01000006_gene751 1.586e-179 573.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family bioA - 2.6.1.113 ko:K12256 ko00330,ko01100,map00330,map01100 - R08714 RC00008,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 TGS3_k127_813333_1 1122137.AQXF01000006_gene750 9.745e-153 494.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,2TRCP@28211|Alphaproteobacteria 28211|Alphaproteobacteria E glutamine synthetase glnA1 - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C TGS3_k127_820369_7 450851.PHZ_c2574 1.877e-26 119.0 COG2234@1|root,COG2234@2|Bacteria,1MUZ7@1224|Proteobacteria,2TRSJ@28211|Alphaproteobacteria,2KG5D@204458|Caulobacterales 204458|Caulobacterales S PA domain - - - - - - - - - - - - PA,Peptidase_M28 TGS3_k127_820369_5 1280954.HPO_12868 8.985e-43 161.0 COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,2U7BD@28211|Alphaproteobacteria,43XZ9@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine panD - 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Asp_decarbox TGS3_k127_820369_9 243233.MCA1422 4.686e-08 66.0 COG5297@1|root,COG5297@2|Bacteria,1QXPR@1224|Proteobacteria,1T3F9@1236|Gammaproteobacteria,1XGNI@135618|Methylococcales 135618|Methylococcales G Belongs to the glycosyl hydrolase family 6 - - - - - - - - - - - - - TGS3_k127_820369_1 314260.PB2503_00987 5.44e-151 482.0 COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,2TS53@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the peptidase S33 family pip - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 TGS3_k127_820369_8 314260.PB2503_00997 6.731e-15 79.0 COG2198@1|root,COG2198@2|Bacteria 2|Bacteria T Histidine kinase MA20_31460 - - - - - - - - - - - Hpt TGS3_k127_820369_3 1247963.JPHU01000005_gene423 8.898e-126 413.0 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2TSM0@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Peptidoglycan polymerase that is essential for cell wall elongation mrdB - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE TGS3_k127_820369_0 1247963.JPHU01000005_gene424 1.617e-221 704.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2TRXN@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG0768 cell division protein FtsI penicillin-binding protein 2 mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase TGS3_k127_820369_6 1247963.JPHU01000005_gene425 1.011e-31 132.0 2DDTT@1|root,32U20@2|Bacteria,1N2J3@1224|Proteobacteria,2UCVI@28211|Alphaproteobacteria 28211|Alphaproteobacteria S shape-determining protein mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD TGS3_k127_820369_4 1247963.JPHU01000005_gene426 1.101e-56 213.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2U1FY@28211|Alphaproteobacteria 28211|Alphaproteobacteria M shape-determining protein MreC mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC TGS3_k127_820369_2 402881.Plav_2479 1.967e-127 410.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2TTQ2@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Rod shape-determining protein (MreB) mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl TGS3_k127_8336_1 1385517.N800_02750 1.598e-19 97.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,1X954@135614|Xanthomonadales 135614|Xanthomonadales K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Trans_reg_C TGS3_k127_8336_0 1122137.AQXF01000007_gene3573 7.273e-239 754.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit MA20_01045 - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N TGS3_k127_854590_6 1185766.DL1_02445 6.404e-35 139.0 COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,2U94I@28211|Alphaproteobacteria,2XNCC@285107|Thioclava 28211|Alphaproteobacteria N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body flgC - - ko:K02388 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C TGS3_k127_854590_9 195105.CN97_13360 2.36e-18 89.0 COG1815@1|root,COG1815@2|Bacteria,1N1G1@1224|Proteobacteria,2UCJ4@28211|Alphaproteobacteria 28211|Alphaproteobacteria N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body flgB - - ko:K02387 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod TGS3_k127_854590_0 1288298.rosmuc_00575 6.52e-121 406.0 COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,2TRXU@28211|Alphaproteobacteria,46PQY@74030|Roseovarius 28211|Alphaproteobacteria NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase fliI - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab,ATP-synt_ab_N TGS3_k127_854590_5 371731.Rsw2DRAFT_0399 3.902e-53 198.0 28NHY@1|root,2ZBJH@2|Bacteria,1RAWQ@1224|Proteobacteria,2TYJH@28211|Alphaproteobacteria,1FCIP@1060|Rhodobacter 28211|Alphaproteobacteria N Protein of unknown function (DUF1217) - - - - - - - - - - - - DUF1217 TGS3_k127_854590_8 1472418.BBJC01000001_gene475 5.04e-21 98.0 COG5443@1|root,COG5443@2|Bacteria,1RD3V@1224|Proteobacteria,2U7PK@28211|Alphaproteobacteria 28211|Alphaproteobacteria N Flagellar biosynthesis repressor FlbT flbT - - ko:K06601 - - - - ko00000,ko02035 - - - FlbT TGS3_k127_854590_12 314254.OA2633_04971 1.515e-10 66.0 COG5442@1|root,COG5442@2|Bacteria,1N1GT@1224|Proteobacteria,2UBRC@28211|Alphaproteobacteria,43Y4U@69657|Hyphomonadaceae 28211|Alphaproteobacteria N Flagellar protein FlaF flaF - - ko:K06602 - - - - ko00000,ko02035 - - - FlaF TGS3_k127_854590_2 1354722.JQLS01000008_gene2926 7.883e-86 292.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,2TUQQ@28211|Alphaproteobacteria,46PH7@74030|Roseovarius 28211|Alphaproteobacteria N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella flaA GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N TGS3_k127_854590_13 314260.PB2503_07924 3.906e-07 55.0 COG3951@1|root,COG3951@2|Bacteria 2|Bacteria MNO Flagellar rod assembly protein muramidase FlgJ flgJ - - ko:K02395,ko:K08309 - - - - ko00000,ko01000,ko01011,ko02035 - GH23 - Rod-binding,SLT TGS3_k127_854590_14 759362.KVU_1922 0.0001278 54.0 COG3144@1|root,COG3144@2|Bacteria,1N882@1224|Proteobacteria,2UG0B@28211|Alphaproteobacteria 28211|Alphaproteobacteria N Flagellar hook-length control protein - - - - - - - - - - - - Flg_hook TGS3_k127_854590_7 349102.Rsph17025_2595 6.304e-28 121.0 COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,2UCHH@28211|Alphaproteobacteria,1FBRR@1060|Rhodobacter 28211|Alphaproteobacteria N Required for flagellar hook formation. May act as a scaffolding protein flgD - - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgD,FlgD_ig TGS3_k127_854590_11 1280953.HOC_13689 4.848e-13 78.0 2AGAB@1|root,316FU@2|Bacteria,1RHRI@1224|Proteobacteria,2U96E@28211|Alphaproteobacteria,44022@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Controls the rotational direction of flagella during chemotaxis fliL2 - - - - - - - - - - - FliL TGS3_k127_854590_3 1415756.JQMY01000001_gene405 3.547e-64 231.0 COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,2TRHN@28211|Alphaproteobacteria,2PCT2@252301|Oceanicola 28211|Alphaproteobacteria N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgH - - ko:K02393 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgH TGS3_k127_854590_10 1550073.JROH01000014_gene53 1.883e-17 89.0 COG1261@1|root,COG1261@2|Bacteria,1PM4C@1224|Proteobacteria,2TRUS@28211|Alphaproteobacteria,2K6AN@204457|Sphingomonadales 204457|Sphingomonadales NO Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly - - - ko:K02386 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - ChapFlgA TGS3_k127_854590_1 1469613.JT55_00310 8.778e-104 343.0 COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,2TRR4@28211|Alphaproteobacteria,3FCX9@34008|Rhodovulum 28211|Alphaproteobacteria N Flagella basal body rod protein flgG GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C TGS3_k127_854590_4 391595.RLO149_c043420 1.057e-53 199.0 COG4786@1|root,COG4786@2|Bacteria,1PZ24@1224|Proteobacteria,2U06G@28211|Alphaproteobacteria,2P218@2433|Roseobacter 28211|Alphaproteobacteria N COG4786 Flagellar basal body rod protein flgF - - ko:K02391,ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C TGS3_k127_855829_0 759362.KVU_1942 2.068e-115 384.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,2TQUR@28211|Alphaproteobacteria 28211|Alphaproteobacteria N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP TGS3_k127_855829_1 509190.Cseg_3177 5.216e-08 61.0 COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,2TTHN@28211|Alphaproteobacteria,2KFQH@204458|Caulobacterales 204458|Caulobacterales N Role in flagellar biosynthesis fliR - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 TGS3_k127_859283_3 1280952.HJA_16993 2.396e-26 112.0 COG3788@1|root,COG3788@2|Bacteria,1RDHP@1224|Proteobacteria,2UEVQ@28211|Alphaproteobacteria,43Y98@69657|Hyphomonadaceae 28211|Alphaproteobacteria S relative of glutathione S-transferase, MAPEG superfamily - - - ko:K07136 - - - - ko00000 - - - MAPEG TGS3_k127_859283_1 1279038.KB907341_gene1812 9.792e-133 437.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2TRUK@28211|Alphaproteobacteria,2JPUE@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the peptidase M20A family. ArgE subfamily argE - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 TGS3_k127_859283_2 1122137.AQXF01000004_gene1674 1.654e-63 224.0 COG2808@1|root,COG2808@2|Bacteria 2|Bacteria K Putative FMN-binding domain paiB - - ko:K07734 - - - - ko00000,ko03000 - - - FMN_bind_2 TGS3_k127_859283_0 1247963.JPHU01000003_gene1514 4.838e-162 518.0 COG0646@1|root,COG0646@2|Bacteria,1NPFY@1224|Proteobacteria,2UJRS@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain metH - 2.1.1.13,2.1.1.5 ko:K00544,ko:K00548 ko00260,ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00260,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R02821,R09365 RC00035,RC00113,RC00496,RC01241 ko00000,ko00001,ko00002,ko01000 - - - S-methyl_trans TGS3_k127_859283_4 1161401.ASJA01000002_gene2687 6.5e-20 99.0 COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,2TWNB@28211|Alphaproteobacteria 28211|Alphaproteobacteria M membrane - - - - - - - - - - - - DUF2339 TGS3_k127_86458_12 582744.Msip34_0935 1.599e-20 100.0 2E83A@1|root,332H7@2|Bacteria,1NK62@1224|Proteobacteria,2W7ZH@28216|Betaproteobacteria,2KMYT@206350|Nitrosomonadales 206350|Nitrosomonadales - - - - - - - - - - - - - - VPEP TGS3_k127_86458_6 1545915.JROG01000001_gene316 1.571e-115 383.0 COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,2TSIF@28211|Alphaproteobacteria,2K209@204457|Sphingomonadales 204457|Sphingomonadales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short TGS3_k127_86458_7 745014.OMB55_00024860 3.423e-112 368.0 COG1028@1|root,COG1028@2|Bacteria,1MVYJ@1224|Proteobacteria 1224|Proteobacteria IQ Short-chain dehydrogenase reductase Sdr MA20_22460 - 1.1.1.127 ko:K00065 ko00040,map00040 - R01542 RC00089 ko00000,ko00001,ko01000 - - - adh_short_C2 TGS3_k127_86458_10 744980.TRICHSKD4_1396 8.324e-22 100.0 2E6PV@1|root,331A6@2|Bacteria,1N9B4@1224|Proteobacteria,2UH6Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3995) - - - - - - - - - - - - DUF3995 TGS3_k127_86458_15 935557.ATYB01000014_gene2645 2.817e-08 55.0 COG5611@1|root,COG5611@2|Bacteria,1N9JM@1224|Proteobacteria,2UFF7@28211|Alphaproteobacteria,4BE09@82115|Rhizobiaceae 28211|Alphaproteobacteria S PIN domain vapC - - - - - - - - - - - PIN TGS3_k127_86458_14 266834.SMc01176 2.477e-10 63.0 COG2002@1|root,COG2002@2|Bacteria,1N7NX@1224|Proteobacteria,2UKQV@28211|Alphaproteobacteria 28211|Alphaproteobacteria K SpoVT / AbrB like domain - - - - - - - - - - - - MazE_antitoxin TGS3_k127_86458_2 1247963.JPHU01000003_gene1233 1.321e-267 835.0 COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2TQKA@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g TGS3_k127_86458_9 1280948.HY36_07015 1.264e-42 161.0 2CHCP@1|root,32S5R@2|Bacteria,1MZ97@1224|Proteobacteria,2U9KI@28211|Alphaproteobacteria,43Y10@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 TGS3_k127_86458_5 1127673.GLIP_1562 2.842e-131 432.0 COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,1RNBI@1236|Gammaproteobacteria,463YT@72275|Alteromonadaceae 1236|Gammaproteobacteria G Sugar (and other) transporter - - - - - - - - - - - - MFS_1 TGS3_k127_86458_3 1342302.JASC01000010_gene2525 7.696e-138 452.0 COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2TQMF@28211|Alphaproteobacteria,3ZWZ0@60136|Sulfitobacter 28211|Alphaproteobacteria C Zinc-binding dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N TGS3_k127_86458_4 856793.MICA_362 5.22e-137 444.0 COG0492@1|root,COG0492@2|Bacteria,1MW14@1224|Proteobacteria,2TSKU@28211|Alphaproteobacteria,4BPNG@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase MA20_08170 - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_3 TGS3_k127_86458_0 1125973.JNLC01000016_gene2822 0.0 1146.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2TS9E@28211|Alphaproteobacteria,3JTU7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 TGS3_k127_86458_1 1123503.KB908056_gene1545 1.839e-315 980.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2TW70@28211|Alphaproteobacteria,2KJVP@204458|Caulobacterales 204458|Caulobacterales E Prolyl oligopeptidase, N-terminal beta-propeller domain - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N TGS3_k127_86458_11 1161401.ASJA01000018_gene1179 2.655e-21 101.0 COG3827@1|root,COG3827@2|Bacteria,1MX61@1224|Proteobacteria,2TSG8@28211|Alphaproteobacteria,43YDD@69657|Hyphomonadaceae 28211|Alphaproteobacteria S protein conserved in bacteria - - - ko:K09991 - - - - ko00000 - - - DUF2497 TGS3_k127_86458_8 1333998.M2A_0513 3.004e-50 187.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2TR3S@28211|Alphaproteobacteria,4BQ21@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria MU Outer membrane efflux protein tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP TGS3_k127_868678_4 1247963.JPHU01000004_gene575 1.088e-33 135.0 COG2267@1|root,COG2267@2|Bacteria,1MWDA@1224|Proteobacteria,2TSZ4@28211|Alphaproteobacteria 28211|Alphaproteobacteria I alpha, beta pldB - 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 TGS3_k127_868678_0 1247963.JPHU01000004_gene468 0.0 1144.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family ttgE - - ko:K18989 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30 - - ACR_tran TGS3_k127_868678_1 991905.SL003B_2727 2.215e-78 275.0 COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,2TRSC@28211|Alphaproteobacteria,4BQQP@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K18990 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30,8.A.1 - - Biotin_lipoyl_2,HlyD_D23 TGS3_k127_868678_3 1165096.ARWF01000001_gene461 2.801e-45 174.0 COG0489@1|root,COG0489@2|Bacteria,1PHBP@1224|Proteobacteria,2W93I@28216|Betaproteobacteria,2KNKF@206350|Nitrosomonadales 206350|Nitrosomonadales D protein tyrosine kinase activity - - - - - - - - - - - - - TGS3_k127_868678_2 1101195.Meth11DRAFT_1093 4.653e-68 252.0 COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2VMDA@28216|Betaproteobacteria,2KNQ0@206350|Nitrosomonadales 206350|Nitrosomonadales M Chain length determinant protein - - - - - - - - - - - - Wzz TGS3_k127_877017_0 1040986.ATYO01000034_gene109 1.551e-90 307.0 COG0583@1|root,COG0583@2|Bacteria,1R51E@1224|Proteobacteria,2TZIK@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate TGS3_k127_877017_1 187303.BN69_2142 1.098e-72 252.0 COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,2TRJM@28211|Alphaproteobacteria 28211|Alphaproteobacteria O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA,Redoxin TGS3_k127_877017_3 420324.KI912069_gene6362 1.115e-43 168.0 COG1917@1|root,COG1917@2|Bacteria,1PBNJ@1224|Proteobacteria,2U1VG@28211|Alphaproteobacteria,1JY54@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Cupin - - - - - - - - - - - - Cupin_2 TGS3_k127_877017_2 1380391.JIAS01000011_gene4709 6.303e-47 177.0 COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,2TR0R@28211|Alphaproteobacteria,2JR1G@204441|Rhodospirillales 204441|Rhodospirillales EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1 TGS3_k127_884823_3 1280953.HOC_07188 1.128e-60 233.0 COG3710@1|root,COG5616@1|root,COG3710@2|Bacteria,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,2TWZ1@28211|Alphaproteobacteria,44159@69657|Hyphomonadaceae 28211|Alphaproteobacteria K cAMP biosynthetic process - - - - - - - - - - - - Guanylate_cyc,Trans_reg_C TGS3_k127_884823_0 1280954.HPO_06583 1.702e-178 564.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2TRAD@28211|Alphaproteobacteria,43WK2@69657|Hyphomonadaceae 28211|Alphaproteobacteria J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C TGS3_k127_884823_4 1123503.KB908059_gene401 1.297e-13 78.0 2EP02@1|root,33GKW@2|Bacteria,1NNMT@1224|Proteobacteria,2UN01@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - TGS3_k127_884823_1 1282876.BAOK01000001_gene1220 5.378e-83 279.0 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2TT6Q@28211|Alphaproteobacteria,4BQ8B@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro TGS3_k127_884823_2 314260.PB2503_09309 3.74e-69 242.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2U5P0@28211|Alphaproteobacteria 28211|Alphaproteobacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C TGS3_k127_925995_0 1161401.ASJA01000012_gene808 0.0 1048.0 COG3544@1|root,COG3544@2|Bacteria,1NTI3@1224|Proteobacteria,2UMCM@28211|Alphaproteobacteria,43Z3F@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF305) - - - - - - - - - - - - DUF305 TGS3_k127_925995_1 588932.JHOF01000001_gene505 2.57e-173 565.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSUQ@28211|Alphaproteobacteria,2KFHP@204458|Caulobacterales 204458|Caulobacterales S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 TGS3_k127_925995_4 1280954.HPO_00275 2.587e-42 177.0 COG3710@1|root,COG5616@1|root,COG3710@2|Bacteria,COG5616@2|Bacteria,1PF3H@1224|Proteobacteria,2V7F9@28211|Alphaproteobacteria,43YSF@69657|Hyphomonadaceae 28211|Alphaproteobacteria K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - TPR_16,Trans_reg_C TGS3_k127_925995_5 118161.KB235922_gene5337 2.884e-11 72.0 COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1GC8T@1117|Cyanobacteria 1117|Cyanobacteria Q Lactonase, 7-bladed beta-propeller - - - - - - - - - - - - HemolysinCabind,Lactonase TGS3_k127_925995_3 158500.BV97_00660 5.025e-137 447.0 COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,2K2R1@204457|Sphingomonadales 204457|Sphingomonadales P Ring hydroxylating alpha subunit (catalytic domain) - - - - - - - - - - - - Rieske,Ring_hydroxyl_A TGS3_k127_925995_2 883126.HMPREF9710_04584 1.627e-148 477.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2VRSD@28216|Betaproteobacteria,475NM@75682|Oxalobacteraceae 28216|Betaproteobacteria Q Thi4 family - - - - - - - - - - - - Amino_oxidase,DAO,NAD_binding_8 TGS3_k127_9276_1 190650.CC_2565 3.816e-92 311.0 COG0596@1|root,COG0596@2|Bacteria,1R8PJ@1224|Proteobacteria,2U5KM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 TGS3_k127_9276_3 251221.35213252 2.48e-55 197.0 COG0454@1|root,COG0456@2|Bacteria,1G6QB@1117|Cyanobacteria 1117|Cyanobacteria K PFAM Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 TGS3_k127_9276_6 1254432.SCE1572_05160 3.196e-18 93.0 COG1309@1|root,COG1309@2|Bacteria,1MUUY@1224|Proteobacteria,42VQ5@68525|delta/epsilon subdivisions,2WSX2@28221|Deltaproteobacteria,2YZU5@29|Myxococcales 28221|Deltaproteobacteria K WHG domain - - - - - - - - - - - - TetR_N,WHG TGS3_k127_9276_4 1121124.JNIX01000007_gene266 2.555e-30 124.0 COG0346@1|root,COG0346@2|Bacteria,1NA4J@1224|Proteobacteria,2UG20@28211|Alphaproteobacteria,2KHIV@204458|Caulobacterales 204458|Caulobacterales E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase TGS3_k127_9276_2 394221.Mmar10_2564 4.589e-91 306.0 COG2941@1|root,COG2941@2|Bacteria,1R4IU@1224|Proteobacteria,2U0RX@28211|Alphaproteobacteria,43WDI@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Alternative oxidase - - 1.10.3.11 ko:K17893 - - R09504 RC00061 ko00000,ko01000 - - - AOX TGS3_k127_9276_0 1123059.KB823013_gene514 2.286e-213 681.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria,43Z38@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Leukotriene A4 hydrolase, C-terminal - - - - - - - - - - - - Leuk-A4-hydro_C,Peptidase_M1 TGS3_k127_936042_5 717785.HYPMC_1508 0.0001175 47.0 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2TUND@28211|Alphaproteobacteria,3N8RA@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria K helix_turn_helix, Lux Regulon - - - ko:K14987 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg TGS3_k127_936042_3 745310.G432_17635 2.416e-80 276.0 COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,2TSQS@28211|Alphaproteobacteria,2K3TI@204457|Sphingomonadales 204457|Sphingomonadales K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg TGS3_k127_936042_2 509190.Cseg_2074 2.357e-110 377.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQX3@28211|Alphaproteobacteria,2KJ1R@204458|Caulobacterales 204458|Caulobacterales T PFAM ATP-binding region ATPase domain protein - - - - - - - - - - - - HATPase_c,HisKA TGS3_k127_936042_1 627192.SLG_10650 1.003e-111 367.0 COG2267@1|root,COG2267@2|Bacteria,1PWCZ@1224|Proteobacteria,2U4MM@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_6 TGS3_k127_936042_0 1297865.APJD01000003_gene6412 2.641e-156 498.0 COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,2TRUA@28211|Alphaproteobacteria,3JRAQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Function of homologous gene experimentally demonstrated in an other organism - - 1.11.1.10 ko:K00433 - - - - ko00000,ko01000 - - - Abhydrolase_1,Hydrolase_4 TGS3_k127_936042_4 1530186.JQEY01000001_gene697 2.838e-10 66.0 COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Resolvase - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom TGS3_k127_94274_1 702113.PP1Y_AT36420 6.015e-169 557.0 COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,1MXVP@1224|Proteobacteria,2TTT1@28211|Alphaproteobacteria,2K0D4@204457|Sphingomonadales 204457|Sphingomonadales HP receptor - - - - - - - - - - - - Plug,TonB_dep_Rec TGS3_k127_94274_0 1081640.AGFU01000023_gene2259 3.592e-216 677.0 COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,2U2DZ@28211|Alphaproteobacteria,2K1P7@204457|Sphingomonadales 204457|Sphingomonadales G Sugar transporter - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 TGS3_k127_9757_0 1247963.JPHU01000012_gene932 0.0 1480.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria 28211|Alphaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran TGS3_k127_9757_3 1280949.HAD_16047 1.238e-63 223.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,43XK6@69657|Hyphomonadaceae 28211|Alphaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB TGS3_k127_9757_10 1280944.HY17_08730 3.528e-05 55.0 COG1574@1|root,COG1574@2|Bacteria,1R53N@1224|Proteobacteria,2VF84@28211|Alphaproteobacteria 28211|Alphaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 TGS3_k127_9757_1 1247963.JPHU01000009_gene2412 0.0 1292.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW TGS3_k127_9757_6 1121948.AUAC01000008_gene783 2.638e-41 168.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria,43XE3@69657|Hyphomonadaceae 28211|Alphaproteobacteria O Peptidylprolyl isomerase prsA - 5.2.1.8 ko:K01802,ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3 TGS3_k127_9757_4 1217720.ALOX01000018_gene850 2.308e-49 179.0 COG0494@1|root,COG1670@1|root,COG0494@2|Bacteria,COG1670@2|Bacteria,1RCZM@1224|Proteobacteria,2U7A4@28211|Alphaproteobacteria,2JS44@204441|Rhodospirillales 204441|Rhodospirillales JL Belongs to the Nudix hydrolase family - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - Acetyltransf_3,NUDIX,NUDIX_4 TGS3_k127_9757_2 59538.XP_005973456.1 1.906e-75 262.0 COG0500@1|root,KOG2940@2759|Eukaryota,38S4I@33154|Opisthokonta,3BCAZ@33208|Metazoa,3CUJX@33213|Bilateria,48446@7711|Chordata,48W7W@7742|Vertebrata,3JBN1@40674|Mammalia,4J3XP@91561|Cetartiodactyla 33208|Metazoa Q NADH dehydrogenase ubiquinone 1 alpha subcomplex assembly factor - - - ko:K18162 ko04714,map04714 - - - ko00000,ko00001,ko01000,ko03029 - - - Methyltransf_11 TGS3_k127_9757_8 631454.N177_2152 4.002e-13 79.0 COG4961@1|root,COG4961@2|Bacteria,1N744@1224|Proteobacteria,2UGR2@28211|Alphaproteobacteria,1JPES@119043|Rhodobiaceae 28211|Alphaproteobacteria U TadE-like protein - - - - - - - - - - - - TadE TGS3_k127_9757_7 551789.ATVJ01000001_gene1127 4.306e-18 94.0 COG4961@1|root,COG4961@2|Bacteria,1N3XK@1224|Proteobacteria,2UBRJ@28211|Alphaproteobacteria,43XYP@69657|Hyphomonadaceae 28211|Alphaproteobacteria U TadE-like protein - - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - TadE TGS3_k127_9757_5 1333998.M2A_1839 2.177e-42 177.0 COG4961@1|root,COG4961@2|Bacteria,1MWXU@1224|Proteobacteria,2TRQP@28211|Alphaproteobacteria,4BQFA@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad,VWA TGS3_k127_979330_0 1280950.HJO_09564 4.114e-195 617.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,43W7I@69657|Hyphomonadaceae 28211|Alphaproteobacteria S COG1473 Metal-dependent amidase aminoacylase carboxypeptidase - - - - - - - - - - - - M20_dimer,Peptidase_M20 TGS3_k127_979330_2 1161401.ASJA01000021_gene649 5.749e-35 153.0 COG1225@1|root,COG1225@2|Bacteria,1MZN4@1224|Proteobacteria,2UA7Y@28211|Alphaproteobacteria,43XZ6@69657|Hyphomonadaceae 28211|Alphaproteobacteria O alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA TGS3_k127_979330_1 1211115.ALIQ01000179_gene1558 9.511e-188 595.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,3NAW1@45404|Beijerinckiaceae 28211|Alphaproteobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA ## 2737 queries scanned ## Total time (seconds): 167.7081425189972 ## Rate: 16.32 q/s