## Thu Oct 17 11:02:01 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/TH3_bin.19.fa -m mmseqs --itype genome -o TH3_bin.19 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/TH3_bin.19 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
TH3_k127_1040887_12	481448.Minf_1665	8.34e-43	161.0	COG0825@1|root,COG0825@2|Bacteria,46SE1@74201|Verrucomicrobia,37G5V@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
TH3_k127_1040887_7	1396141.BATP01000023_gene745	1.375e-91	312.0	COG1482@1|root,COG1482@2|Bacteria,46SVM@74201|Verrucomicrobia,2IU31@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphomannose isomerase type I	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
TH3_k127_1040887_17	331678.Cphamn1_1444	2.596e-17	89.0	COG1950@1|root,COG1950@2|Bacteria,1FE4Y@1090|Chlorobi	1090|Chlorobi	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
TH3_k127_1040887_13	497964.CfE428DRAFT_0169	5.644e-40	155.0	COG0220@1|root,COG0220@2|Bacteria,46T5A@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
TH3_k127_1040887_5	1122223.KB890700_gene1996	7.329e-114	377.0	COG0687@1|root,COG0687@2|Bacteria,1WIRI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Spermidine putrescine-binding periplasmic protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
TH3_k127_1040887_9	321332.CYB_2209	8.756e-86	295.0	COG1177@1|root,COG1177@2|Bacteria,1G1B6@1117|Cyanobacteria,1H1XK@1129|Synechococcus	1117|Cyanobacteria	P	ABC transporter, permease protein	potC	-	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
TH3_k127_1040887_8	321327.CYA_1858	1.491e-87	298.0	COG1176@1|root,COG1176@2|Bacteria,1G127@1117|Cyanobacteria,1H1QV@1129|Synechococcus	1117|Cyanobacteria	P	ABC transporter, permease protein	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
TH3_k127_1040887_4	684949.ATTJ01000001_gene2613	2.464e-114	383.0	COG3842@1|root,COG3842@2|Bacteria,1WIWM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
TH3_k127_1040887_6	1396141.BATP01000040_gene2101	7.946e-103	352.0	COG5267@1|root,COG5267@2|Bacteria,46SWV@74201|Verrucomicrobia,2IVM0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
TH3_k127_1040887_3	1396141.BATP01000040_gene2102	4.669e-127	423.0	COG4102@1|root,COG4102@2|Bacteria,46T50@74201|Verrucomicrobia,2IUKB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TH3_k127_1040887_10	1396141.BATP01000032_gene4347	2.646e-66	235.0	COG0386@1|root,COG0386@2|Bacteria,46V2M@74201|Verrucomicrobia,2IUDT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	GSHPx
TH3_k127_1040887_11	1122915.AUGY01000087_gene5226	8.285e-56	212.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,26S70@186822|Paenibacillaceae	91061|Bacilli	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
TH3_k127_1040887_16	661478.OP10G_4802	2.433e-17	91.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_1040887_19	1123242.JH636435_gene2068	1.268e-07	64.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
TH3_k127_1040887_14	1449357.JQLK01000001_gene1667	1.534e-32	149.0	2A1UA@1|root,30Q39@2|Bacteria,1WM6W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1040887_20	1283299.AUKG01000003_gene290	0.000121	57.0	COG1524@1|root,COG2936@1|root,COG1524@2|Bacteria,COG2936@2|Bacteria,2GJ2K@201174|Actinobacteria	201174|Actinobacteria	E	dipeptidyl-peptidase	-	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PepX_C,Peptidase_S15
TH3_k127_1040887_2	745411.B3C1_05050	4.128e-127	461.0	COG3055@1|root,COG3391@1|root,COG5184@1|root,COG5276@1|root,COG3055@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1QUHA@1224|Proteobacteria,1T1YV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
TH3_k127_1040887_18	1163398.AJJP01000075_gene2559	4.434e-11	78.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria,1R4Z6@1224|Proteobacteria	1224|Proteobacteria	Q	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1040887_0	1117318.PRUB_07755	1.348e-270	865.0	COG2866@1|root,COG2866@2|Bacteria,1N9W9@1224|Proteobacteria,1RPC7@1236|Gammaproteobacteria,2Q1BI@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
TH3_k127_1040887_1	1120965.AUBV01000010_gene2835	8.434e-267	839.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,47KWW@768503|Cytophagia	976|Bacteroidetes	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
TH3_k127_1040887_21	1123508.JH636448_gene7581	0.0007844	42.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_107081_5	497964.CfE428DRAFT_2619	3.096e-18	100.0	COG2374@1|root,COG3420@1|root,COG4733@1|root,COG5184@1|root,COG2374@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,46TRJ@74201|Verrucomicrobia	74201|Verrucomicrobia	DZ	Domains in Na-Ca exchangers and integrin-beta4	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF5122
TH3_k127_107081_3	1121920.AUAU01000009_gene1881	7.572e-48	196.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
TH3_k127_107081_2	1229204.AMYY01000035_gene834	4.258e-53	213.0	COG1409@1|root,COG1409@2|Bacteria,1R67V@1224|Proteobacteria,2U3E2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos
TH3_k127_107081_4	1123278.KB893571_gene2226	4.549e-20	104.0	COG1319@1|root,COG3210@1|root,COG4886@1|root,COG1319@2|Bacteria,COG3210@2|Bacteria,COG4886@2|Bacteria,4NTNN@976|Bacteroidetes	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP,SprB
TH3_k127_107081_6	768706.Desor_1391	5.722e-09	68.0	COG2247@1|root,COG3386@1|root,COG2247@2|Bacteria,COG3386@2|Bacteria,1VMQN@1239|Firmicutes	1239|Firmicutes	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
TH3_k127_107081_0	1192034.CAP_0893	2.258e-57	226.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
TH3_k127_107081_1	575540.Isop_1614	1.009e-54	218.0	COG2373@1|root,COG2373@2|Bacteria,2IZBV@203682|Planctomycetes	203682|Planctomycetes	Q	aggregation factor core protein MAFp3, isoform C	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP_2
TH3_k127_1104090_27	935948.KE386493_gene2375	3.967e-45	179.0	arCOG07336@1|root,2Z8ST@2|Bacteria,1TRXN@1239|Firmicutes,248NM@186801|Clostridia,42HXG@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1104090_33	1121904.ARBP01000052_gene3650	1.875e-27	125.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	AXE1,Hydrolase_4
TH3_k127_1104090_28	880070.Cycma_2352	7.905e-41	172.0	COG3669@1|root,COG3669@2|Bacteria,4NHRG@976|Bacteroidetes,47TRP@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
TH3_k127_1104090_46	1449355.JQNR01000005_gene5972	7.504e-06	59.0	COG3055@1|root,COG4934@1|root,COG3055@2|Bacteria,COG4934@2|Bacteria,2IF2T@201174|Actinobacteria	201174|Actinobacteria	O	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Kelch_1
TH3_k127_1104090_37	1168059.KB899087_gene3167	1.214e-21	113.0	COG1409@1|root,COG2931@1|root,COG1409@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3EZXC@335928|Xanthobacteraceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CBM60,HemolysinCabind,Metallophos,PPC,Peptidase_M10_C
TH3_k127_1104090_25	1121920.AUAU01000009_gene1881	1.405e-53	218.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
TH3_k127_1104090_40	1303518.CCALI_00913	5.713e-17	91.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_1104090_30	1123296.JQKE01000075_gene375	1.698e-37	156.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,2KPMA@206351|Neisseriales	206351|Neisseriales	KLT	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
TH3_k127_1104090_38	497964.CfE428DRAFT_0698	9.444e-21	97.0	COG3558@1|root,COG3558@2|Bacteria,46T07@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
TH3_k127_1104090_36	575609.HMPREF0629_01045	3.334e-22	105.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24MVR@186801|Clostridia,22HAS@1570339|Peptoniphilaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
TH3_k127_1104090_3	1396418.BATQ01000026_gene5276	8.74e-195	613.0	COG0156@1|root,COG0156@2|Bacteria,46SSH@74201|Verrucomicrobia,2ITW1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TH3_k127_1104090_10	497964.CfE428DRAFT_4082	1.513e-151	491.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF3472,DUF5077,Gram_pos_anchor,Reprolysin_4
TH3_k127_1104090_32	1403819.BATR01000151_gene5104	2.199e-29	139.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,PATR
TH3_k127_1104090_29	1403819.BATR01000069_gene2031	2.733e-39	171.0	COG1470@1|root,COG1749@1|root,COG3291@1|root,COG3506@1|root,COG3533@1|root,COG1470@2|Bacteria,COG1749@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria,COG3533@2|Bacteria,46SQ1@74201|Verrucomicrobia,2IV3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1104090_43	376686.Fjoh_2456	9.908e-12	80.0	COG3866@1|root,COG3866@2|Bacteria,4NJUK@976|Bacteroidetes,1IIIB@117743|Flavobacteriia,2NUS2@237|Flavobacterium	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1104090_45	980584.AFPB01000131_gene3192	1.328e-06	63.0	COG2730@1|root,COG3401@1|root,COG2730@2|Bacteria,COG3401@2|Bacteria,4PPCW@976|Bacteroidetes,1I8FJ@117743|Flavobacteriia,4079T@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1104090_20	697281.Mahau_0407	1.556e-71	257.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,42F5Y@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TH3_k127_1104090_0	497964.CfE428DRAFT_4093	0.0	1517.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,46SAP@74201|Verrucomicrobia	74201|Verrucomicrobia	CE	Proline dehydrogenase	-	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
TH3_k127_1104090_6	497964.CfE428DRAFT_4081	1.388e-185	598.0	COG1063@1|root,COG1063@2|Bacteria,46UMA@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
TH3_k127_1104090_17	1396418.BATQ01000026_gene5273	5.327e-82	277.0	COG1476@1|root,COG1917@1|root,COG1476@2|Bacteria,COG1917@2|Bacteria,46TBZ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19
TH3_k127_1104090_42	886293.Sinac_3116	9.049e-12	75.0	COG2165@1|root,COG2165@2|Bacteria,2IZ6K@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_1104090_2	1403819.BATR01000087_gene2529	3.143e-231	720.0	COG2873@1|root,COG2873@2|Bacteria,46TEJ@74201|Verrucomicrobia,2ITJ5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
TH3_k127_1104090_11	102129.Lepto7375DRAFT_2106	1.994e-136	444.0	COG2021@1|root,COG2021@2|Bacteria,1G4G5@1117|Cyanobacteria,1HHP2@1150|Oscillatoriales	1117|Cyanobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
TH3_k127_1104090_22	452637.Oter_0095	3.661e-68	253.0	COG4942@1|root,COG4942@2|Bacteria,46U5A@74201|Verrucomicrobia,3K7T2@414999|Opitutae	414999|Opitutae	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1104090_23	452637.Oter_0096	5.471e-64	241.0	2EWFD@1|root,33PTV@2|Bacteria,46UNG@74201|Verrucomicrobia,3K7NI@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1104090_8	1396418.BATQ01000078_gene594	1.516e-168	537.0	COG0577@1|root,COG0577@2|Bacteria,46UQN@74201|Verrucomicrobia,2IVBP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TH3_k127_1104090_9	1403819.BATR01000150_gene5077	7.079e-155	499.0	COG0577@1|root,COG0577@2|Bacteria,46UT6@74201|Verrucomicrobia,2IVGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TH3_k127_1104090_14	452637.Oter_1514	1.624e-114	375.0	COG1136@1|root,COG1136@2|Bacteria,46YZ8@74201|Verrucomicrobia,3K9FX@414999|Opitutae	414999|Opitutae	P	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_1104090_12	1396418.BATQ01000078_gene597	3.093e-129	424.0	COG0845@1|root,COG0845@2|Bacteria,46UZZ@74201|Verrucomicrobia,2IVAY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
TH3_k127_1104090_1	452637.Oter_4609	1.578e-306	959.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OPT
TH3_k127_1104090_5	1121920.AUAU01000007_gene416	8.36e-186	599.0	COG1164@1|root,COG1164@2|Bacteria,3Y2SB@57723|Acidobacteria	57723|Acidobacteria	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
TH3_k127_1104090_13	278957.ABEA03000206_gene3779	1.814e-120	395.0	COG0379@1|root,COG0379@2|Bacteria,46SA1@74201|Verrucomicrobia,3K7P4@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
TH3_k127_1104090_39	497964.CfE428DRAFT_0242	4.215e-20	107.0	COG1858@1|root,COG3391@1|root,COG3534@1|root,COG5276@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,COG3534@2|Bacteria,COG5276@2|Bacteria,46U43@74201|Verrucomicrobia	74201|Verrucomicrobia	C	SMART LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD,Laminin_G_3,PKD
TH3_k127_1104090_19	1168289.AJKI01000040_gene3174	1.39e-72	277.0	2DYE6@1|root,349BE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1104090_18	452637.Oter_1332	1.251e-79	275.0	COG1075@1|root,COG1075@2|Bacteria,46VJF@74201|Verrucomicrobia,3K9J6@414999|Opitutae	414999|Opitutae	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1104090_4	1242864.D187_003088	5.05e-189	623.0	COG2931@1|root,COG3055@1|root,COG2931@2|Bacteria,COG3055@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
TH3_k127_1104090_26	1125701.HMPREF1221_01616	2.765e-48	191.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1104090_24	1279009.ADICEAN_01670	5.93e-62	218.0	COG0590@1|root,COG0590@2|Bacteria,4NNMU@976|Bacteroidetes,47PPK@768503|Cytophagia	976|Bacteroidetes	FJ	MafB19-like deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	MafB19-deam,dCMP_cyt_deam_1
TH3_k127_1104090_16	1128427.KB904821_gene1968	1.05e-82	289.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TH3_k127_1104090_34	292564.Cyagr_1911	9.627e-24	114.0	COG2337@1|root,COG2337@2|Bacteria,1G7JA@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM PemK-like protein	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
TH3_k127_1104090_7	497964.CfE428DRAFT_5010	2.743e-176	564.0	COG1940@1|root,COG1940@2|Bacteria,46SBQ@74201|Verrucomicrobia	74201|Verrucomicrobia	GK	carbohydrate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1104090_15	530564.Psta_1962	1.359e-94	327.0	28J2H@1|root,2Z8YZ@2|Bacteria,2IWTN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1104090_41	1120950.KB892753_gene6100	2.551e-13	83.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_39
TH3_k127_1104090_21	479434.Sthe_1775	3.279e-71	249.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_1104090_35	40571.JOEA01000008_gene2733	3.635e-23	117.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4DXTW@85010|Pseudonocardiales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TH3_k127_1104090_31	868131.MSWAN_1282	6.901e-31	131.0	COG0655@1|root,arCOG02573@2157|Archaea,2XVMU@28890|Euryarchaeota,23PMW@183925|Methanobacteria	183925|Methanobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
TH3_k127_1104090_44	1210884.HG799464_gene10380	1.179e-07	53.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
TH3_k127_1105609_1	497964.CfE428DRAFT_3913	2.065e-164	527.0	COG3119@1|root,COG3119@2|Bacteria,46TFH@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TH3_k127_1105609_7	264732.Moth_0582	2.527e-79	280.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,42F9T@68295|Thermoanaerobacterales	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
TH3_k127_1105609_12	247490.KSU1_C0931	1.21e-21	98.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
TH3_k127_1105609_2	497964.CfE428DRAFT_1789	1.365e-148	482.0	COG0195@1|root,COG0195@2|Bacteria,46TRP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
TH3_k127_1105609_0	478741.JAFS01000002_gene929	2.751e-190	622.0	COG0532@1|root,COG0532@2|Bacteria,46S8V@74201|Verrucomicrobia,37FYY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
TH3_k127_1105609_13	32057.KB217478_gene5529	1.289e-12	73.0	COG0858@1|root,COG0858@2|Bacteria,1G6JJ@1117|Cyanobacteria,1HNRI@1161|Nostocales	1117|Cyanobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
TH3_k127_1105609_8	497964.CfE428DRAFT_1792	1.07e-67	242.0	COG0618@1|root,COG0618@2|Bacteria,46T03@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM phosphoesterase RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
TH3_k127_1105609_6	452637.Oter_2817	3.122e-80	273.0	COG0130@1|root,COG0130@2|Bacteria,46SJR@74201|Verrucomicrobia,3K75I@414999|Opitutae	414999|Opitutae	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
TH3_k127_1105609_10	1396418.BATQ01000085_gene1110	3.622e-66	239.0	COG0196@1|root,COG0196@2|Bacteria,46SZ6@74201|Verrucomicrobia,2IU48@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
TH3_k127_1105609_3	1379698.RBG1_1C00001G1779	1.054e-145	470.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TH3_k127_1105609_16	237368.SCABRO_02173	1.065e-07	54.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
TH3_k127_1105609_15	883080.HMPREF9697_02951	9.246e-08	55.0	COG3668@1|root,COG3668@2|Bacteria,1N569@1224|Proteobacteria	1224|Proteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
TH3_k127_1105609_17	1137269.AZWL01000006_gene6788	3.922e-06	57.0	COG0666@1|root,COG0666@2|Bacteria,2IIAC@201174|Actinobacteria	201174|Actinobacteria	T	Ankyrin repeat	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4,Ank_5
TH3_k127_1105609_14	317655.Sala_2653	3.167e-08	64.0	2BZB1@1|root,32R4P@2|Bacteria,1RH72@1224|Proteobacteria,2UB2J@28211|Alphaproteobacteria,2KA29@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1105609_5	237368.SCABRO_01880	2.024e-97	332.0	COG1721@1|root,COG1721@2|Bacteria,2IXT7@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TH3_k127_1105609_11	237368.SCABRO_01881	8.316e-23	107.0	2DQN8@1|root,337RD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1105609_4	497964.CfE428DRAFT_3459	6.184e-98	331.0	COG2304@1|root,COG2304@2|Bacteria,46TTR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA
TH3_k127_1105609_9	1167006.UWK_00742	3.459e-66	234.0	COG0457@1|root,COG2304@1|root,COG5414@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,COG5414@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_16,TPR_2,VWA,VWA_2
TH3_k127_1105754_2	1123508.JH636448_gene7581	1.376e-29	121.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_1105754_0	452637.Oter_0312	5.56e-126	451.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
TH3_k127_1105754_1	1121104.AQXH01000001_gene1014	6.228e-88	303.0	COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes,1IPXF@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
TH3_k127_1105754_3	1348657.M622_01280	6.734e-17	95.0	COG3291@1|root,COG3291@2|Bacteria,1QUSE@1224|Proteobacteria	1224|Proteobacteria	G	PFAM FecR protein	-	-	3.2.1.4	ko:K01179,ko:K03933	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	AA10,CBM73,GH5,GH9	-	CBM_2,Calx-beta,Cellulase,PKD
TH3_k127_123781_1	616991.JPOO01000003_gene1322	4.388e-132	428.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,23G5Z@178469|Arenibacter	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
TH3_k127_123781_0	1123242.JH636436_gene531	1.325e-153	501.0	COG1225@1|root,COG4409@1|root,COG4692@1|root,COG1225@2|Bacteria,COG4409@2|Bacteria,COG4692@2|Bacteria,2J06F@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TH3_k127_123781_2	1123508.JH636439_gene1235	6.616e-33	128.0	COG3119@1|root,COG3119@2|Bacteria,2IXQ5@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TH3_k127_1241735_3	452637.Oter_2792	2.859e-135	444.0	COG1198@1|root,COG1198@2|Bacteria,46U3N@74201|Verrucomicrobia,3K7V0@414999|Opitutae	414999|Opitutae	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
TH3_k127_1241735_10	497964.CfE428DRAFT_0066	1.343e-82	300.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
TH3_k127_1241735_23	234267.Acid_3225	1.013e-27	130.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_8,Trans_reg_C
TH3_k127_1241735_32	313628.LNTAR_12286	2.362e-12	77.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_1241735_33	1038862.KB893833_gene4667	1.227e-11	78.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,2TTVN@28211|Alphaproteobacteria,3JXXS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1241735_27	102125.Xen7305DRAFT_00020060	8.615e-20	104.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CW_binding_1,VCBS
TH3_k127_1241735_7	1097668.BYI23_C006580	5.168e-95	329.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	msrB	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,PMSR,Redoxin,SelR,Thioredoxin
TH3_k127_1241735_13	1229205.BUPH_01539	7.294e-71	259.0	COG4409@1|root,COG4409@2|Bacteria,1Q513@1224|Proteobacteria,2WB3C@28216|Betaproteobacteria,1K536@119060|Burkholderiaceae	28216|Betaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_2
TH3_k127_1241735_17	497964.CfE428DRAFT_0064	1.743e-56	205.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
TH3_k127_1241735_19	518766.Rmar_1172	4.137e-51	193.0	COG1999@1|root,COG5569@1|root,COG1999@2|Bacteria,COG5569@2|Bacteria,4PEVF@976|Bacteroidetes,1FJP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	CusF_Ec,SCO1-SenC
TH3_k127_1241735_20	1396418.BATQ01000001_gene1289	1.768e-35	142.0	COG1321@1|root,COG1321@2|Bacteria,46VZN@74201|Verrucomicrobia,2IUJN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
TH3_k127_1241735_22	452637.Oter_1500	5.536e-29	123.0	COG3824@1|root,COG3824@2|Bacteria,46WK7@74201|Verrucomicrobia,3K8CH@414999|Opitutae	414999|Opitutae	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
TH3_k127_1241735_11	326427.Cagg_0204	9.572e-74	273.0	COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia	32061|Chloroflexia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
TH3_k127_1241735_15	1121403.AUCV01000002_gene446	7.166e-62	226.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,42P50@68525|delta/epsilon subdivisions,2WKU5@28221|Deltaproteobacteria,2MMX2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
TH3_k127_1241735_37	533240.CRC_01736	8.627e-07	58.0	COG4276@1|root,COG4276@2|Bacteria,1G939@1117|Cyanobacteria,1HNWV@1161|Nostocales	1117|Cyanobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1241735_28	1407650.BAUB01000015_gene2280	5.029e-18	100.0	COG1178@1|root,COG1178@2|Bacteria,1GCQ2@1117|Cyanobacteria	1117|Cyanobacteria	P	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	-
TH3_k127_1241735_18	314230.DSM3645_08622	1.09e-54	219.0	COG3391@1|root,COG3391@2|Bacteria,2IYRP@203682|Planctomycetes	203682|Planctomycetes	P	RING finger protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,NHL
TH3_k127_1241735_1	1128421.JAGA01000003_gene3234	1.261e-150	513.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2NQSS@2323|unclassified Bacteria	2|Bacteria	S	Putative glutamine amidotransferase	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,GATase1_like,VWA,VWA_2,VWA_3
TH3_k127_1241735_29	240016.ABIZ01000001_gene2409	7.545e-17	85.0	COG1254@1|root,COG1254@2|Bacteria,46W9W@74201|Verrucomicrobia,2IUZQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Acylphosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Acylphosphatase
TH3_k127_1241735_6	497964.CfE428DRAFT_1198	2.573e-101	334.0	COG0639@1|root,COG0639@2|Bacteria,46TA5@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	apaH	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
TH3_k127_1241735_16	330214.NIDE3030	6.645e-57	212.0	COG0859@1|root,COG0859@2|Bacteria,3J0KI@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02841,ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
TH3_k127_1241735_31	1396141.BATP01000036_gene3819	1.385e-13	81.0	2EV5U@1|root,33NKM@2|Bacteria,46WDA@74201|Verrucomicrobia,2IUTJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1241735_14	497964.CfE428DRAFT_3176	3.761e-65	238.0	COG1820@1|root,COG1820@2|Bacteria,46SRF@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
TH3_k127_1241735_8	497964.CfE428DRAFT_2661	2.989e-94	315.0	COG1714@1|root,COG1714@2|Bacteria,46UT5@74201|Verrucomicrobia	74201|Verrucomicrobia	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
TH3_k127_1241735_5	439235.Dalk_0975	1.228e-118	392.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,42UUJ@68525|delta/epsilon subdivisions,2WQQ0@28221|Deltaproteobacteria,2MNT3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
TH3_k127_1241735_0	497964.CfE428DRAFT_2659	1.223e-161	522.0	COG1721@1|root,COG1721@2|Bacteria,46SN6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TH3_k127_1241735_2	497964.CfE428DRAFT_2658	8.483e-149	479.0	COG0714@1|root,COG0714@2|Bacteria,46S8X@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TH3_k127_1241735_12	497964.CfE428DRAFT_2657	1.845e-73	269.0	COG5414@1|root,COG5414@2|Bacteria,46VD3@74201|Verrucomicrobia	74201|Verrucomicrobia	K	histone acetyltransferase binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1241735_4	497964.CfE428DRAFT_2656	1.888e-127	427.0	2EQIM@1|root,2ZBQ8@2|Bacteria,46TFZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
TH3_k127_1241735_24	497964.CfE428DRAFT_2655	1.655e-26	111.0	2ES4R@1|root,33JPJ@2|Bacteria,46T9B@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1241735_30	398767.Glov_3581	2.332e-14	83.0	2B0DH@1|root,31SQS@2|Bacteria,1P6ED@1224|Proteobacteria,4328H@68525|delta/epsilon subdivisions,2WXMR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1241735_21	439235.Dalk_0968	4.539e-31	129.0	2ECUE@1|root,336RY@2|Bacteria,1P3V9@1224|Proteobacteria,431ZA@68525|delta/epsilon subdivisions,2WX45@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1241735_26	583355.Caka_1232	1.715e-22	109.0	COG5523@1|root,COG5523@2|Bacteria,46ZK6@74201|Verrucomicrobia,3KA3R@414999|Opitutae	2|Bacteria	S	Domain of unknown function (DUF4339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
TH3_k127_1241735_35	771875.Ferpe_1246	9.727e-10	62.0	COG0230@1|root,COG0230@2|Bacteria,2GDMP@200918|Thermotogae	200918|Thermotogae	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
TH3_k127_1241735_34	756499.Desde_4254	1.815e-11	70.0	COG0594@1|root,COG0594@2|Bacteria,1TV50@1239|Firmicutes,259HJ@186801|Clostridia,2633N@186807|Peptococcaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
TH3_k127_1241735_25	1244869.H261_16660	3.446e-23	104.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2UFKH@28211|Alphaproteobacteria,2JTTP@204441|Rhodospirillales	204441|Rhodospirillales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
TH3_k127_1241735_9	583355.Caka_2475	2.856e-87	311.0	COG0706@1|root,COG0706@2|Bacteria,46SHI@74201|Verrucomicrobia,3K72P@414999|Opitutae	414999|Opitutae	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
TH3_k127_1241735_36	644282.Deba_0272	5.975e-07	53.0	COG1847@1|root,COG1847@2|Bacteria,1RB1P@1224|Proteobacteria,42QPK@68525|delta/epsilon subdivisions,2WN58@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Single-stranded nucleic acid binding R3H	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
TH3_k127_1243527_1	497964.CfE428DRAFT_6141	8.39e-91	304.0	COG0190@1|root,COG0190@2|Bacteria,46TG7@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
TH3_k127_1243527_0	1117958.PE143B_0100145	1.147e-161	524.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_24,rve
TH3_k127_1243527_2	658187.LDG_5972	5.23e-56	214.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,1RNUA@1236|Gammaproteobacteria,1JGHQ@118969|Legionellales	1236|Gammaproteobacteria	L	IstB-like ATP binding protein	istB3	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
TH3_k127_1245880_2	479435.Kfla_4525	2.216e-33	134.0	COG1957@1|root,COG1957@2|Bacteria	2|Bacteria	F	ribosylpyrimidine nucleosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
TH3_k127_1245880_1	886293.Sinac_7535	1.223e-107	363.0	COG5434@1|root,COG5434@2|Bacteria,2IX4K@203682|Planctomycetes	2|Bacteria	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
TH3_k127_1245880_0	1122931.AUAE01000028_gene113	1.905e-246	785.0	2CB8C@1|root,33T5I@2|Bacteria,4P0N1@976|Bacteroidetes,2FX4B@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1253725_1	452637.Oter_2229	3.889e-47	179.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Glyco_hydro_16,Glyco_transf_25,Malectin,Ricin_B_lectin,Trans_reg_C,Trypsin,VCBS
TH3_k127_1253725_0	1288963.ADIS_1256	1.444e-158	514.0	COG3408@1|root,COG3408@2|Bacteria,4NIK8@976|Bacteroidetes	976|Bacteroidetes	G	Trehalase	ygjK	-	-	ko:K03931	-	-	-	-	ko00000	-	GH63	-	Trehalase
TH3_k127_1253725_3	1227487.C474_19834	0.0002445	46.0	COG1525@1|root,arCOG03192@2157|Archaea,2XTIT@28890|Euryarchaeota,23RYX@183963|Halobacteria	183963|Halobacteria	L	COG1525 Micrococcal nuclease (thermonuclease) homologs	nuc	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	LTD,SNase
TH3_k127_1253725_2	497964.CfE428DRAFT_0108	4.684e-09	68.0	2CMJG@1|root,32SEZ@2|Bacteria,46T0G@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1271845_4	1121920.AUAU01000024_gene2384	1.013e-24	115.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
TH3_k127_1271845_1	1121920.AUAU01000024_gene2386	1.139e-115	379.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
TH3_k127_1271845_0	243231.GSU2888	1.539e-161	528.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42ZYI@68525|delta/epsilon subdivisions,2WVGV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
TH3_k127_1271845_2	1121920.AUAU01000024_gene2381	1.303e-51	205.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
TH3_k127_1284743_24	1396141.BATP01000003_gene4975	0.0003225	49.0	COG1361@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,46WJ7@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
TH3_k127_1284743_0	234267.Acid_6855	2.957e-212	671.0	COG3119@1|root,COG3119@2|Bacteria,3Y7MP@57723|Acidobacteria	57723|Acidobacteria	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TH3_k127_1284743_22	1396141.BATP01000019_gene1718	2.351e-12	78.0	COG3225@1|root,COG3225@2|Bacteria,46UZA@74201|Verrucomicrobia,2IUBV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
TH3_k127_1284743_19	1191523.MROS_2048	1.916e-21	109.0	COG0737@1|root,COG3303@1|root,COG0737@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1,SBP_bac_8,SLH
TH3_k127_1284743_12	452637.Oter_2583	5.136e-88	299.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	omcI	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
TH3_k127_1284743_17	452637.Oter_0906	1.25e-46	179.0	COG0664@1|root,COG0664@2|Bacteria,46VK1@74201|Verrucomicrobia,3K7W4@414999|Opitutae	74201|Verrucomicrobia	K	Crp Fnr family	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TH3_k127_1284743_6	382464.ABSI01000010_gene3644	7.281e-117	388.0	COG0407@1|root,COG0407@2|Bacteria,46X9N@74201|Verrucomicrobia,2IV4H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
TH3_k127_1284743_2	583355.Caka_2769	1.418e-159	515.0	COG0635@1|root,COG0635@2|Bacteria,46TQX@74201|Verrucomicrobia,3K7DD@414999|Opitutae	414999|Opitutae	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
TH3_k127_1284743_23	391625.PPSIR1_12288	1.195e-07	60.0	COG4914@1|root,COG4914@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
TH3_k127_1284743_7	1379270.AUXF01000005_gene406	2.654e-112	379.0	COG1232@1|root,COG1232@2|Bacteria,1ZUZT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
TH3_k127_1284743_5	382464.ABSI01000005_gene1230	5.108e-117	385.0	COG0276@1|root,COG0276@2|Bacteria,46XCA@74201|Verrucomicrobia,2IVEM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Ferrochelatase	-	-	-	-	-	-	-	-	-	-	-	-	Ferrochelatase
TH3_k127_1284743_4	1550073.JROH01000032_gene1995	1.695e-122	408.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,2K21U@204457|Sphingomonadales	204457|Sphingomonadales	E	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
TH3_k127_1284743_25	1123070.KB899250_gene635	0.0006183	48.0	COG1918@1|root,COG1918@2|Bacteria,46ZGK@74201|Verrucomicrobia,2IWG5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	FeoA domain	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
TH3_k127_1284743_3	742725.HMPREF9450_01261	5.9e-135	446.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,4PAMG@976|Bacteroidetes,2FXAJ@200643|Bacteroidia	976|Bacteroidetes	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
TH3_k127_1284743_8	1304885.AUEY01000104_gene2548	1.416e-108	370.0	COG0702@1|root,COG0702@2|Bacteria,1Q438@1224|Proteobacteria,439WM@68525|delta/epsilon subdivisions,2X29K@28221|Deltaproteobacteria,2MPBK@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
TH3_k127_1284743_10	880526.KE386488_gene1576	1.359e-88	324.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1284743_16	349741.Amuc_1932	4.271e-61	228.0	COG0251@1|root,COG0251@2|Bacteria,46V5Y@74201|Verrucomicrobia,2IW47@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
TH3_k127_1284743_11	697281.Mahau_2725	1.873e-88	303.0	COG0407@1|root,COG0407@2|Bacteria,1TR8Q@1239|Firmicutes,24B2U@186801|Clostridia,42IQ4@68295|Thermoanaerobacterales	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	2.1.1.246,4.1.1.37	ko:K01599,ko:K14080	ko00680,ko00860,ko01100,ko01110,ko01120,ko01200,map00680,map00860,map01100,map01110,map01120,map01200	M00121,M00356	R03197,R04972,R09098,R10000	RC00035,RC00872,RC01144,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
TH3_k127_1284743_14	903818.KI912269_gene107	3.013e-66	239.0	COG0646@1|root,COG0646@2|Bacteria,3Y7SY@57723|Acidobacteria	57723|Acidobacteria	E	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
TH3_k127_1284743_13	234267.Acid_6968	1.289e-76	263.0	COG5012@1|root,COG5012@2|Bacteria,3Y88D@57723|Acidobacteria	57723|Acidobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
TH3_k127_1284743_20	278957.ABEA03000093_gene4635	7.387e-20	94.0	arCOG03330@1|root,2Z82Q@2|Bacteria	2|Bacteria	S	PFAM Methanol-cobalamin methyltransferase B subunit	-	-	2.1.1.90	ko:K04480	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00356	R04384,R09098	RC00035,RC01144,RC01145,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	MtaB
TH3_k127_1284743_1	1123242.JH636435_gene1092	1.14e-178	570.0	COG0673@1|root,COG0673@2|Bacteria,2IX39@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_1284743_18	519989.ECTPHS_02009	6.456e-45	170.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
TH3_k127_1284743_15	497964.CfE428DRAFT_4864	2.164e-64	227.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_129016_7	243090.RB11663	1.41e-83	287.0	COG0477@1|root,COG0477@2|Bacteria,2IWYM@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TH3_k127_129016_0	497964.CfE428DRAFT_5033	6.385e-209	651.0	COG1541@1|root,COG1541@2|Bacteria,46UFN@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_129016_13	497964.CfE428DRAFT_0111	4.64e-23	117.0	2CMJG@1|root,32SEZ@2|Bacteria,46T0G@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_129016_16	886293.Sinac_2826	1.55e-06	62.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
TH3_k127_129016_9	497964.CfE428DRAFT_4167	1.085e-76	263.0	COG1208@1|root,COG1208@2|Bacteria,46SP1@74201|Verrucomicrobia	74201|Verrucomicrobia	JM	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
TH3_k127_129016_11	382464.ABSI01000012_gene2250	4.804e-51	184.0	COG0102@1|root,COG0102@2|Bacteria,46VEU@74201|Verrucomicrobia,2IUBQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
TH3_k127_129016_12	1341157.RF007C_09585	7.408e-41	156.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
TH3_k127_129016_1	497964.CfE428DRAFT_2151	3.074e-128	418.0	COG0002@1|root,COG0002@2|Bacteria,46SA3@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
TH3_k127_129016_4	497964.CfE428DRAFT_2167	4.985e-106	361.0	COG1364@1|root,COG1364@2|Bacteria,46SEP@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
TH3_k127_129016_10	886293.Sinac_5728	6.485e-72	248.0	COG2264@1|root,COG2264@2|Bacteria,2J3H0@203682|Planctomycetes	203682|Planctomycetes	J	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
TH3_k127_129016_3	661478.OP10G_0808	3.175e-114	378.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
TH3_k127_129016_8	497964.CfE428DRAFT_2254	2.825e-78	269.0	COG2197@1|root,COG2197@2|Bacteria,46TQM@74201|Verrucomicrobia	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_129016_2	1403819.BATR01000025_gene850	4.346e-119	403.0	COG4585@1|root,COG4585@2|Bacteria,46UGH@74201|Verrucomicrobia,2IVFF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TH3_k127_129016_15	1303518.CCALI_02394	1.044e-06	56.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_129016_6	1042376.AFPK01000062_gene1333	1.934e-98	350.0	COG2503@1|root,COG2503@2|Bacteria,4PN2E@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_129016_14	1237149.C900_04129	8.443e-14	85.0	COG2911@1|root,COG3469@1|root,COG3979@1|root,COG2911@2|Bacteria,COG3469@2|Bacteria,COG3979@2|Bacteria,4PKBR@976|Bacteroidetes,47Y17@768503|Cytophagia	976|Bacteroidetes	G	Carbohydrate binding domain	-	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005576,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016798,GO:0017144,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,CarboxypepD_reg,Glyco_hydro_18
TH3_k127_129016_5	452637.Oter_0691	3.013e-100	334.0	COG0548@1|root,COG0548@2|Bacteria,46SH9@74201|Verrucomicrobia,3K7U8@414999|Opitutae	414999|Opitutae	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
TH3_k127_1314490_12	1123277.KB893244_gene5105	2.64e-16	85.0	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
TH3_k127_1314490_13	497964.CfE428DRAFT_0072	4.161e-16	81.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
TH3_k127_1314490_19	1123035.ARLA01000028_gene2103	2.474e-05	54.0	COG2350@1|root,COG2350@2|Bacteria,4NRC1@976|Bacteroidetes,1I447@117743|Flavobacteriia	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
TH3_k127_1314490_2	1496688.ER33_13835	5.821e-129	414.0	COG0426@1|root,COG0426@2|Bacteria,1GPET@1117|Cyanobacteria,22SW2@167375|Cyanobium	1117|Cyanobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1314490_9	1403819.BATR01000008_gene271	5.451e-25	111.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,2IU2N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
TH3_k127_1314490_17	111781.Lepto7376_3756	6.151e-12	79.0	COG1572@1|root,COG3209@1|root,COG3210@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CARDB,RHS_repeat
TH3_k127_1314490_1	223192.XP_007915956.1	3.298e-136	458.0	COG4030@1|root,2SKR2@2759|Eukaryota,39W5K@33154|Opisthokonta,3NXCY@4751|Fungi,3QPYP@4890|Ascomycota,21CB8@147550|Sordariomycetes	4751|Fungi	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
TH3_k127_1314490_8	1403819.BATR01000005_gene177	2.295e-32	145.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TYP@74201|Verrucomicrobia,2IVFI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,VCBS
TH3_k127_1314490_0	1499967.BAYZ01000095_gene4126	9.028e-295	914.0	COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
TH3_k127_1314490_10	314345.SPV1_00507	3.429e-21	98.0	COG2192@1|root,COG2192@2|Bacteria,1R3MX@1224|Proteobacteria	1224|Proteobacteria	O	nodulation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1314490_11	439235.Dalk_4189	8.608e-17	92.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TH3_k127_1314490_16	1191523.MROS_1643	2.13e-12	69.0	2EGPU@1|root,33AFZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1314490_7	497964.CfE428DRAFT_2202	6.992e-44	181.0	COG3307@1|root,COG3307@2|Bacteria,46TC1@74201|Verrucomicrobia	74201|Verrucomicrobia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
TH3_k127_1314490_18	889378.Spiaf_1773	6.601e-08	63.0	COG2885@1|root,COG4254@1|root,COG2885@2|Bacteria,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	1.9.3.1	ko:K02275,ko:K03286	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.6,3.D.4.2,3.D.4.4,3.D.4.6	-	-	Big_2,COX2,COX2_TM,FecR,OmpA,TPR_16,fn3
TH3_k127_1314490_6	404380.Gbem_0296	4.821e-46	190.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
TH3_k127_1314490_5	497964.CfE428DRAFT_3893	4.53e-56	201.0	COG0669@1|root,COG0669@2|Bacteria,46SUT@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
TH3_k127_1314490_15	313628.LNTAR_24436	1.353e-13	78.0	COG1399@1|root,COG1399@2|Bacteria	2|Bacteria	K	metal-binding, possibly nucleic acid-binding protein	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
TH3_k127_1314490_14	316067.Geob_2610	6.255e-14	74.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,42XHF@68525|delta/epsilon subdivisions,2WSX6@28221|Deltaproteobacteria,43SSW@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	structural constituent of ribosome	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
TH3_k127_1314490_4	497964.CfE428DRAFT_3890	1.072e-83	290.0	COG0416@1|root,COG0416@2|Bacteria,46S8C@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
TH3_k127_1314490_3	497964.CfE428DRAFT_3889	9.921e-122	407.0	COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
TH3_k127_1333022_19	886293.Sinac_1477	5.97e-23	109.0	COG1073@1|root,COG1073@2|Bacteria,2IYBP@203682|Planctomycetes	203682|Planctomycetes	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1333022_12	545694.TREPR_0418	3.315e-53	202.0	COG1262@1|root,COG1262@2|Bacteria,2J5Y8@203691|Spirochaetes	203691|Spirochaetes	C	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Flavodoxin_4
TH3_k127_1333022_16	370438.PTH_1110	5.491e-33	143.0	COG1388@1|root,COG1388@2|Bacteria,1VJ2T@1239|Firmicutes,24YEF@186801|Clostridia,264FH@186807|Peptococcaceae	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1333022_5	1454007.JAUG01000047_gene512	1.173e-167	539.0	COG0673@1|root,COG0673@2|Bacteria,4NJ92@976|Bacteroidetes,1ISF7@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_1333022_18	1395587.P364_0117575	2.164e-25	114.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,26TDT@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_1333022_10	240016.ABIZ01000001_gene1086	2.043e-89	300.0	COG0605@1|root,COG0605@2|Bacteria,46SQF@74201|Verrucomicrobia,2IU40@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Iron/manganese superoxide dismutases, alpha-hairpin domain	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
TH3_k127_1333022_9	382464.ABSI01000011_gene2675	8.562e-116	391.0	COG2610@1|root,COG2610@2|Bacteria,46UQS@74201|Verrucomicrobia,2IVYC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	GntP family permease	-	-	-	-	-	-	-	-	-	-	-	-	GntP_permease
TH3_k127_1333022_14	1123508.JH636439_gene1058	2.679e-49	184.0	COG4221@1|root,COG4221@2|Bacteria,2IYVR@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TH3_k127_1333022_4	497964.CfE428DRAFT_0139	6.993e-175	554.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_1333022_0	1123242.JH636434_gene3346	0.0	1187.0	COG2010@1|root,COG2010@2|Bacteria,2IXJ6@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
TH3_k127_1333022_2	1396418.BATQ01000142_gene3267	9.277e-219	687.0	COG3119@1|root,COG3119@2|Bacteria,46Z2W@74201|Verrucomicrobia,2IWNY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TH3_k127_1333022_15	269482.Bcep1808_5363	4.941e-47	173.0	COG0454@1|root,COG0456@2|Bacteria,1QTYD@1224|Proteobacteria,2WGHN@28216|Betaproteobacteria,1K7F9@119060|Burkholderiaceae	28216|Betaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
TH3_k127_1333022_11	1403819.BATR01000017_gene538	6.737e-57	202.0	COG1764@1|root,COG1764@2|Bacteria,46VXJ@74201|Verrucomicrobia,2IW5Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
TH3_k127_1333022_13	1123508.JH636443_gene5018	2.819e-51	187.0	COG3324@1|root,COG3324@2|Bacteria,2J3W8@203682|Planctomycetes	203682|Planctomycetes	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
TH3_k127_1333022_17	1396141.BATP01000059_gene2546	8.142e-28	118.0	2CIV9@1|root,34A52@2|Bacteria,46W0H@74201|Verrucomicrobia,2IUYN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
TH3_k127_1333022_3	1403819.BATR01000191_gene6501	1.497e-211	668.0	COG3119@1|root,COG3119@2|Bacteria,46S9C@74201|Verrucomicrobia,2ITNC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
TH3_k127_1333022_7	1122605.KB893648_gene3690	5.85e-150	498.0	28J61@1|root,2Z91S@2|Bacteria,4NKJU@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_129
TH3_k127_1333022_1	1123248.KB893318_gene4130	2.168e-311	992.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,1IUSY@117747|Sphingobacteriia	976|Bacteroidetes	G	family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
TH3_k127_1333022_8	414684.RC1_3258	1.114e-121	398.0	COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,2TS5U@28211|Alphaproteobacteria,2JQFB@204441|Rhodospirillales	204441|Rhodospirillales	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
TH3_k127_1333022_6	661478.OP10G_0590	2.797e-165	548.0	COG3940@1|root,COG3940@2|Bacteria	2|Bacteria	G	arabinan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N,Glyco_hydro_43,Laminin_G_3
TH3_k127_135343_1	1499967.BAYZ01000095_gene4060	4.437e-120	390.0	COG4806@1|root,COG4806@2|Bacteria	2|Bacteria	G	L-rhamnose isomerase activity	rhaA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008270,GO:0008740,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0022607,GO:0030145,GO:0030246,GO:0032991,GO:0033296,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046872,GO:0046914,GO:0048029,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901575	2.7.1.5,5.3.1.14	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R02437,R03014	RC00002,RC00017,RC00434	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_3092,iUMNK88_1353.UMNK88_4739	RhaA
TH3_k127_135343_0	234267.Acid_5934	1.13e-138	451.0	COG0697@1|root,2Z7ID@2|Bacteria,3Y46C@57723|Acidobacteria	57723|Acidobacteria	EG	PFAM RhaT l-rhamnose-proton symport 2	-	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
TH3_k127_135343_2	1123278.KB893616_gene3404	3.12e-118	391.0	COG3408@1|root,COG3408@2|Bacteria,4NHST@976|Bacteroidetes,47KY3@768503|Cytophagia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C
TH3_k127_1353870_0	1380391.JIAS01000005_gene2382	6.218e-47	182.0	COG2730@1|root,COG2730@2|Bacteria,1R544@1224|Proteobacteria,2U1MT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Putative collagen-binding domain of a collagenase	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
TH3_k127_1353870_2	357808.RoseRS_2630	1.324e-11	79.0	COG1874@1|root,COG1874@2|Bacteria,2GBMG@200795|Chloroflexi,376H5@32061|Chloroflexia	32061|Chloroflexia	G	Flagellar filament outer layer protein Flaa	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42,Glyco_hydro_cc
TH3_k127_1353870_1	313628.LNTAR_07649	5.627e-12	69.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored,TAT_signal
TH3_k127_1362857_1	179408.Osc7112_3719	5.88e-56	203.0	COG5113@1|root,COG3236@2|Bacteria	2|Bacteria	O	hydrolase activity, hydrolyzing N-glycosyl compounds	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1362857_3	1541065.JRFE01000026_gene2372	2.523e-25	114.0	2A0EN@1|root,30NID@2|Bacteria,1GFBC@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF1877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1877
TH3_k127_1362857_2	1056512.D515_03190	1.583e-26	116.0	2E4QM@1|root,32ZJ7@2|Bacteria,1NEXN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1362857_4	497964.CfE428DRAFT_4009	5.083e-24	105.0	2EG51@1|root,339WY@2|Bacteria,46WHK@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1362857_5	1121896.JMLU01000001_gene1198	2.332e-14	89.0	COG2356@1|root,COG2356@2|Bacteria,4PNZR@976|Bacteroidetes	976|Bacteroidetes	L	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9
TH3_k127_1362857_0	867845.KI911784_gene1260	2.197e-64	254.0	COG0823@1|root,COG1520@1|root,COG0823@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K03641,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.C.1.2	-	-	DUF11,HYR,PD40,PQQ_2,VCBS
TH3_k127_1362857_6	1303518.CCALI_01975	7.45e-14	76.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_1371115_2	880073.Calab_1549	4.662e-81	284.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
TH3_k127_1371115_0	497964.CfE428DRAFT_5643	0.0	1090.0	COG3391@1|root,COG3391@2|Bacteria,46SN2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
TH3_k127_1371115_1	497964.CfE428DRAFT_0327	1.304e-82	293.0	COG1361@1|root,COG1404@1|root,COG4733@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG4733@2|Bacteria,46UDB@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	ASH,DUF5122
TH3_k127_1371247_2	477974.Daud_0876	2.251e-12	68.0	COG1410@1|root,COG1410@2|Bacteria,1VRVS@1239|Firmicutes,25EJA@186801|Clostridia,26050@186807|Peptococcaceae	186801|Clostridia	E	PFAM Pterin binding enzyme	acsE	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
TH3_k127_1371247_1	1540257.JQMW01000013_gene1215	2.28e-46	180.0	COG1810@1|root,COG1810@2|Bacteria,1V28Y@1239|Firmicutes,24DXC@186801|Clostridia,36DES@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF166
TH3_k127_1371247_0	504728.K649_12990	1.316e-81	280.0	COG1526@1|root,COG1526@2|Bacteria,1WJAY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
TH3_k127_1383461_10	870187.Thini_4435	2.055e-05	55.0	28XJT@1|root,2ZJGX@2|Bacteria,1P89B@1224|Proteobacteria,1SWA4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1383461_8	794903.OPIT5_03260	3.837e-22	108.0	COG4783@1|root,COG4783@2|Bacteria,46TAI@74201|Verrucomicrobia,3K7ZQ@414999|Opitutae	414999|Opitutae	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1383461_4	497964.CfE428DRAFT_1756	1.253e-72	259.0	COG2207@1|root,COG2207@2|Bacteria,46T4M@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, arabinose operon control protein	araC	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TH3_k127_1383461_2	497964.CfE428DRAFT_2397	3.365e-117	386.0	COG1858@1|root,COG1858@2|Bacteria,46SJU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Di-haem cytochrome c peroxidase	mauG	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
TH3_k127_1383461_9	661478.OP10G_1795	3.894e-15	86.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_1383461_1	903818.KI912268_gene1381	4.224e-145	476.0	COG3863@1|root,COG3863@2|Bacteria	2|Bacteria	T	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
TH3_k127_1383461_0	497964.CfE428DRAFT_4279	1.15e-161	521.0	COG0773@1|root,COG0773@2|Bacteria,46THM@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Mur ligase middle domain protein	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TH3_k127_1383461_6	243090.RB4127	3.921e-45	175.0	COG3568@1|root,COG3568@2|Bacteria,2IZ9W@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TH3_k127_1383461_3	1125863.JAFN01000001_gene1060	2.131e-96	337.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TH3_k127_1383461_5	382464.ABSI01000011_gene2595	1.91e-51	201.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	phoQ	-	2.7.13.3	ko:K07637,ko:K07638,ko:K07717	ko01503,ko02020,ko02026,map01503,map02020,map02026	M00444,M00445,M00518,M00709,M00721,M00723,M00724,M00742,M00743,M00744	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HATPase_c_3,HisKA
TH3_k127_1383461_7	1123278.KB893412_gene2915	3.132e-27	128.0	COG1874@1|root,COG2755@1|root,COG4447@1|root,COG1874@2|Bacteria,COG2755@2|Bacteria,COG4447@2|Bacteria,4NX71@976|Bacteroidetes,47W14@768503|Cytophagia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1401719_1	1249627.D779_3087	1.626e-18	85.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RN50@1236|Gammaproteobacteria,1WXR5@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM release factor H-coupled RctB family protein	-	-	-	ko:K18148	ko01501,map01501	-	-	-	ko00000,ko00001	-	-	-	RtcB
TH3_k127_1401719_0	497964.CfE428DRAFT_2340	5.296e-186	595.0	COG0012@1|root,COG0012@2|Bacteria,46UY8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1405722_0	1396141.BATP01000062_gene4448	1.237e-140	464.0	COG2939@1|root,COG2939@2|Bacteria,46UB7@74201|Verrucomicrobia,2IVCV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
TH3_k127_1405722_1	497964.CfE428DRAFT_5038	9.232e-110	368.0	COG1520@1|root,COG1520@2|Bacteria,46T0C@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
TH3_k127_1405722_3	497964.CfE428DRAFT_3571	2.133e-15	84.0	COG1595@1|root,COG1595@2|Bacteria,46VJX@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TH3_k127_1405722_2	759914.BP951000_1517	8.379e-25	123.0	COG0457@1|root,COG0457@2|Bacteria	759914.BP951000_1517|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1415201_0	1403819.BATR01000181_gene6235	1.933e-182	580.0	COG0162@1|root,COG0162@2|Bacteria,46UVG@74201|Verrucomicrobia,2ITSI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (W and Y)	-	-	-	-	-	-	-	-	-	-	-	-	S4,tRNA-synt_1b
TH3_k127_1415201_1	196490.AUEZ01000020_gene629	1.766e-40	169.0	COG1749@1|root,COG1749@2|Bacteria,1QWWE@1224|Proteobacteria,2TX6F@28211|Alphaproteobacteria,3JUM6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4082,He_PIG
TH3_k127_1416094_7	794903.OPIT5_05700	3.001e-104	344.0	COG1136@1|root,COG1136@2|Bacteria,46SKR@74201|Verrucomicrobia,3K7HB@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_1416094_5	278957.ABEA03000041_gene2087	6.911e-115	382.0	COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia,3K7M9@414999|Opitutae	414999|Opitutae	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TH3_k127_1416094_2	575540.Isop_0300	9.057e-134	437.0	COG2382@1|root,COG2382@2|Bacteria,2IYMZ@203682|Planctomycetes	203682|Planctomycetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
TH3_k127_1416094_1	448385.sce0660	9.27e-137	463.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,43B64@68525|delta/epsilon subdivisions,2X6JN@28221|Deltaproteobacteria,2YVQ4@29|Myxococcales	28221|Deltaproteobacteria	CP	sodium ABC transporter, permease	-	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,Abi
TH3_k127_1416094_8	1254432.SCE1572_04430	8.069e-102	338.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,43C30@68525|delta/epsilon subdivisions,2X7DN@28221|Deltaproteobacteria,2YUXV@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	-	ABC_tran
TH3_k127_1416094_0	1123242.JH636436_gene628	2.599e-167	538.0	COG1502@1|root,COG1502@2|Bacteria,2IY2H@203682|Planctomycetes	203682|Planctomycetes	I	Phospholipase_D-nuclease N-terminal	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
TH3_k127_1416094_3	1232410.KI421414_gene2911	4.502e-129	427.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,43BUU@68525|delta/epsilon subdivisions,2WKYP@28221|Deltaproteobacteria,43STX@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TH3_k127_1416094_11	1123070.KB899254_gene1243	5.967e-31	126.0	COG0838@1|root,COG0838@2|Bacteria,46T33@74201|Verrucomicrobia,2IUK0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
TH3_k127_1416094_12	481448.Minf_0649	4.059e-18	85.0	COG3071@1|root,COG3071@2|Bacteria,46TBM@74201|Verrucomicrobia,37H13@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
TH3_k127_1416094_4	1304880.JAGB01000002_gene1563	6.297e-127	430.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TH3_k127_1416094_10	1191523.MROS_1090	6.783e-61	216.0	COG0693@1|root,COG0693@2|Bacteria	2|Bacteria	S	protein deglycation	pfpI	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
TH3_k127_1416094_9	452637.Oter_3080	3.94e-63	228.0	2CIBN@1|root,2Z8JT@2|Bacteria	2|Bacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
TH3_k127_1416094_15	1137799.GZ78_08895	1.327e-06	63.0	COG0689@1|root,COG0726@1|root,COG2911@1|root,COG2931@1|root,COG3055@1|root,COG3533@1|root,COG5434@1|root,COG0689@2|Bacteria,COG0726@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3533@2|Bacteria,COG5434@2|Bacteria,1MU7T@1224|Proteobacteria,1S3Q4@1236|Gammaproteobacteria,1XK3E@135619|Oceanospirillales	135619|Oceanospirillales	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
TH3_k127_1416094_6	497964.CfE428DRAFT_4839	5.462e-113	375.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TH3_k127_148630_3	886293.Sinac_0410	1.928e-08	65.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
TH3_k127_148630_1	452637.Oter_1389	8.562e-158	525.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TH3_k127_148630_2	452637.Oter_2422	1.633e-57	205.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
TH3_k127_148630_0	1122605.KB893643_gene530	7.984e-218	698.0	COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
TH3_k127_148630_4	1285586.H131_08453	3.883e-05	50.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,3IVXV@400634|Lysinibacillus	91061|Bacilli	F	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
TH3_k127_1536901_1	1120968.AUBX01000009_gene686	9.631e-40	157.0	COG2730@1|root,COG2730@2|Bacteria,4NF3J@976|Bacteroidetes	976|Bacteroidetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
TH3_k127_1536901_0	240016.ABIZ01000001_gene228	7.635e-181	575.0	COG1680@1|root,COG5297@1|root,COG1680@2|Bacteria,COG5297@2|Bacteria,46TK0@74201|Verrucomicrobia,2IVMJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1593
TH3_k127_1536901_2	1396418.BATQ01000011_gene4506	1.007e-19	98.0	COG1680@1|root,COG5297@1|root,COG1680@2|Bacteria,COG5297@2|Bacteria,46TK0@74201|Verrucomicrobia,2IVMJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1593
TH3_k127_1540951_2	497964.CfE428DRAFT_3889	2.564e-63	221.0	COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
TH3_k127_1540951_4	1286632.P278_17170	1.988e-13	78.0	COG0746@1|root,COG0746@2|Bacteria,4NSH9@976|Bacteroidetes,1I46A@117743|Flavobacteriia	976|Bacteroidetes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
TH3_k127_1540951_1	1123242.JH636435_gene1022	3.603e-75	271.0	COG0265@1|root,COG0265@2|Bacteria,2IYNW@203682|Planctomycetes	203682|Planctomycetes	O	C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
TH3_k127_1540951_3	886293.Sinac_6513	6.66e-19	102.0	291K2@1|root,2ZP6D@2|Bacteria,2IZ9X@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
TH3_k127_1540951_0	1131269.AQVV01000050_gene418	1.901e-131	428.0	COG2107@1|root,COG2107@2|Bacteria	2|Bacteria	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K07083,ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
TH3_k127_1540951_5	1229780.BN381_750002	0.0001447	52.0	2C62F@1|root,335K1@2|Bacteria,2GS5K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_154304_2	1403819.BATR01000181_gene6201	1.456e-155	505.0	COG0477@1|root,COG0477@2|Bacteria,46TSP@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TH3_k127_154304_3	1121912.AUHD01000023_gene370	6.719e-67	240.0	28NPX@1|root,2ZBPN@2|Bacteria,4NN00@976|Bacteroidetes,1I1FD@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function DUF2625	-	-	-	-	-	-	-	-	-	-	-	-	DUF2625
TH3_k127_154304_0	497964.CfE428DRAFT_5031	1.622e-224	710.0	COG1520@1|root,COG1520@2|Bacteria,46U89@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
TH3_k127_154304_1	1396418.BATQ01000147_gene3609	1.632e-223	717.0	COG1520@1|root,COG1520@2|Bacteria,46UUP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_154304_4	497964.CfE428DRAFT_5028	4.883e-39	152.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K06075,ko:K22296	-	-	-	-	ko00000,ko03000	-	-	-	MarR,MarR_2
TH3_k127_154304_5	278957.ABEA03000174_gene3362	7.54e-05	52.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_1546643_30	522306.CAP2UW1_0963	2.692e-07	53.0	COG3385@1|root,COG3385@2|Bacteria,1MXYG@1224|Proteobacteria,2VRWD@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase Tn5 dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_Tn5,Tnp_DNA_bind
TH3_k127_1546643_12	1005999.GLGR_3545	4.431e-49	195.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,1RYKD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TH3_k127_1546643_1	204669.Acid345_4052	1.576e-287	901.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
TH3_k127_1546643_16	1227739.Hsw_4156	1.838e-37	158.0	COG0204@1|root,COG0204@2|Bacteria,4NK8Z@976|Bacteroidetes,47NT5@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TH3_k127_1546643_24	316067.Geob_3122	2.785e-22	110.0	COG0236@1|root,COG0236@2|Bacteria,1NE99@1224|Proteobacteria	1224|Proteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1546643_31	197221.22295598	7.785e-06	58.0	COG0236@1|root,COG0236@2|Bacteria,1G9GC@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TH3_k127_1546643_20	886293.Sinac_0620	1.42e-30	132.0	2EEBB@1|root,30UIG@2|Bacteria,2J420@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1546643_27	991.IW20_16285	3.318e-15	87.0	COG1470@1|root,COG3386@1|root,COG1470@2|Bacteria,COG3386@2|Bacteria,4PKCK@976|Bacteroidetes,1IJ7K@117743|Flavobacteriia,2P0KA@237|Flavobacterium	976|Bacteroidetes	G	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1546643_0	404589.Anae109_0189	0.0	1472.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2YVGM@29|Myxococcales	28221|Deltaproteobacteria	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
TH3_k127_1546643_3	1123242.JH636435_gene1594	1.637e-157	511.0	COG1032@1|root,COG1032@2|Bacteria,2IYYP@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
TH3_k127_1546643_15	497964.CfE428DRAFT_1024	9.486e-40	152.0	2EBIG@1|root,335IZ@2|Bacteria,46WF8@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1546643_7	240016.ABIZ01000001_gene654	4.552e-80	277.0	COG0583@1|root,COG0583@2|Bacteria,46V15@74201|Verrucomicrobia,2IUGE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TH3_k127_1546643_21	404589.Anae109_0686	5.419e-28	126.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
TH3_k127_1546643_13	497964.CfE428DRAFT_5735	4.496e-45	183.0	COG4796@1|root,COG4796@2|Bacteria,46STU@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM type II and III secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	Secretin
TH3_k127_1546643_4	1396141.BATP01000032_gene4324	2.188e-157	521.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia,2IU51@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
TH3_k127_1546643_22	452637.Oter_3570	2.949e-25	117.0	COG0265@1|root,COG0265@2|Bacteria,46W40@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1546643_29	794903.OPIT5_11525	4.338e-12	76.0	COG2165@1|root,COG2165@2|Bacteria,46Z9D@74201|Verrucomicrobia,3K9IE@414999|Opitutae	2|Bacteria	U	Protein of unknown function (DUF1559)	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_1546643_2	497964.CfE428DRAFT_3658	1.321e-166	537.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	CBM_6,Glyco_hydro_16,Trypsin,VCBS
TH3_k127_1546643_10	530564.Psta_2414	8.649e-52	186.0	COG0346@1|root,COG0346@2|Bacteria,2J1AZ@203682|Planctomycetes	203682|Planctomycetes	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TH3_k127_1546643_23	794903.OPIT5_29840	1.429e-23	107.0	2FBS3@1|root,307HF@2|Bacteria,46W7T@74201|Verrucomicrobia,3K85M@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1546643_17	240016.ABIZ01000001_gene3878	6.754e-34	141.0	COG2068@1|root,COG2068@2|Bacteria	2|Bacteria	NU	MobA-Related Protein	nboR	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
TH3_k127_1546643_8	1403819.BATR01000112_gene3876	4.557e-80	278.0	COG1082@1|root,COG1082@2|Bacteria,46T96@74201|Verrucomicrobia,2IUNM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_1546643_9	1144275.COCOR_06959	1.269e-74	266.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
TH3_k127_1546643_14	583355.Caka_1943	2.587e-41	158.0	COG1051@1|root,COG1051@2|Bacteria,46V5B@74201|Verrucomicrobia,3K7WB@414999|Opitutae	414999|Opitutae	F	NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
TH3_k127_1546643_5	240016.ABIZ01000001_gene3008	1.223e-147	480.0	COG1520@1|root,COG1520@2|Bacteria,46U6I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_1546643_6	756272.Plabr_2335	5.083e-102	347.0	COG2755@1|root,COG2755@2|Bacteria,2IYGD@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TH3_k127_1546643_26	1142394.PSMK_06110	9.118e-17	91.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_1546643_18	1396141.BATP01000028_gene2285	2.462e-32	148.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
TH3_k127_1546643_25	1396141.BATP01000039_gene1234	6.065e-19	104.0	COG1454@1|root,COG2010@1|root,COG2133@1|root,COG3291@1|root,COG3979@1|root,COG4625@1|root,COG1454@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3979@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	chiA	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	1.1.1.1,1.1.1.61,3.1.3.6,3.1.4.16,3.2.1.14,3.2.1.17	ko:K00001,ko:K00043,ko:K01119,ko:K01183,ko:K03933,ko:K08325,ko:K13381,ko:K13954,ko:K19954	ko00010,ko00071,ko00230,ko00240,ko00350,ko00520,ko00625,ko00626,ko00640,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00230,map00240,map00350,map00520,map00625,map00626,map00640,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220	-	R00623,R00754,R01206,R01562,R01644,R01877,R02124,R02148,R02334,R02370,R02528,R03537,R03538,R03929,R04805,R04880,R05135,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00078,RC00087,RC00088,RC00099,RC00116,RC00296,RC00467,RC00649,RC00739,RC01734,RC02273	ko00000,ko00001,ko01000	-	AA10,CBM15,CBM73,GH18	-	Fe-ADH,GSDH
TH3_k127_1546643_28	498761.HM1_0145	3.648e-14	88.0	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria,1UHXK@1239|Firmicutes,25E6U@186801|Clostridia	186801|Clostridia	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,Flg_new,I-set,Laminin_G_3,SLH
TH3_k127_1546643_11	1123377.AUIV01000014_gene517	2.482e-51	188.0	COG4430@1|root,COG4430@2|Bacteria,1RG2R@1224|Proteobacteria,1T0AD@1236|Gammaproteobacteria,1X6JK@135614|Xanthomonadales	135614|Xanthomonadales	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
TH3_k127_1546643_19	1242864.D187_003284	1.226e-31	125.0	COG5646@1|root,COG5646@2|Bacteria	2|Bacteria	S	Domain of unknown function (DU1801)	XK27_02315	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TH3_k127_1556124_2	1403819.BATR01000017_gene540	2.348e-73	252.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
TH3_k127_1556124_1	497964.CfE428DRAFT_1056	2.197e-143	467.0	COG3119@1|root,COG3119@2|Bacteria,46VGR@74201|Verrucomicrobia	74201|Verrucomicrobia	NP	Ig domain protein group 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Sulfatase
TH3_k127_1556124_3	452637.Oter_2422	2.472e-36	140.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
TH3_k127_1556124_0	1403819.BATR01000016_gene535	1.427e-223	699.0	COG0673@1|root,COG0673@2|Bacteria,46T68@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_1556124_4	402777.KB235904_gene4166	5.756e-15	89.0	COG2931@1|root,COG2931@2|Bacteria,1G0ZC@1117|Cyanobacteria,1H8KD@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
TH3_k127_1583753_4	1537715.JQFJ01000002_gene1346	4.231e-32	147.0	COG2911@1|root,COG3210@1|root,COG3468@1|root,COG4625@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3468@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,2TX9B@28211|Alphaproteobacteria,2KENE@204457|Sphingomonadales	204457|Sphingomonadales	MU	Autotransporter beta-domain	-	-	-	ko:K19231	-	-	-	-	ko00000,ko02000	1.B.12	-	-	PATR
TH3_k127_1583753_6	344747.PM8797T_04455	6.192e-14	81.0	COG2165@1|root,COG2165@2|Bacteria,2J1XE@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_10
TH3_k127_1583753_11	794903.OPIT5_22725	2.606e-09	69.0	COG2165@1|root,COG2165@2|Bacteria,46YHE@74201|Verrucomicrobia,3K9KI@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
TH3_k127_1583753_5	1026882.MAMP_01900	4.155e-30	140.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,461F5@72273|Thiotrichales	72273|Thiotrichales	U	Large exoproteins involved in heme utilization or adhesion	-	-	-	-	-	-	-	-	-	-	-	-	PATR
TH3_k127_1583753_7	1142394.PSMK_04880	1.71e-13	83.0	COG2165@1|root,COG2165@2|Bacteria,2IY1V@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_1583753_10	521674.Plim_1480	8.029e-12	76.0	COG2165@1|root,COG2165@2|Bacteria,2IYXM@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_1583753_1	1396141.BATP01000033_gene4254	3.735e-186	620.0	COG5434@1|root,COG5434@2|Bacteria,46TEZ@74201|Verrucomicrobia,2IWAI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1583753_9	1463820.JOGW01000001_gene5446	4.747e-12	80.0	COG1409@1|root,COG5492@1|root,COG1409@2|Bacteria,COG5492@2|Bacteria,2GKTR@201174|Actinobacteria	201174|Actinobacteria	N	polysaccharide lyase family 8	-	-	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	Lyase_8,Lyase_8_C,Lyase_8_N
TH3_k127_1583753_0	1396418.BATQ01000020_gene5035	3.66e-207	656.0	COG3119@1|root,COG3119@2|Bacteria,46ZJS@74201|Verrucomicrobia,2IVBK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TH3_k127_1583753_3	497964.CfE428DRAFT_1056	8.204e-118	395.0	COG3119@1|root,COG3119@2|Bacteria,46VGR@74201|Verrucomicrobia	74201|Verrucomicrobia	NP	Ig domain protein group 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Sulfatase
TH3_k127_1583753_2	234267.Acid_1623	5.788e-120	395.0	COG2801@1|root,COG2801@2|Bacteria,3Y821@57723|Acidobacteria	57723|Acidobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
TH3_k127_1583753_8	653733.Selin_0475	9.377e-13	68.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_32
TH3_k127_1635565_5	44251.PDUR_01820	1.432e-90	306.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,26T63@186822|Paenibacillaceae	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TH3_k127_1635565_16	506534.Rhein_0083	2.811e-07	61.0	COG0457@1|root,COG0457@2|Bacteria,1RKT6@1224|Proteobacteria,1S7R3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1635565_1	1396141.BATP01000003_gene5043	5.198e-237	741.0	COG1233@1|root,COG1233@2|Bacteria,46SE8@74201|Verrucomicrobia,2IVA7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
TH3_k127_1635565_14	1158292.JPOE01000002_gene3555	6.638e-12	69.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
TH3_k127_1635565_9	240016.ABIZ01000001_gene1135	7.852e-41	155.0	COG1943@1|root,COG1943@2|Bacteria,46W84@74201|Verrucomicrobia,2IVXZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
TH3_k127_1635565_12	682795.AciX8_1298	1.726e-17	86.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
TH3_k127_1635565_4	1396141.BATP01000003_gene5044	8.405e-95	321.0	COG1215@1|root,COG1215@2|Bacteria,46WX3@74201|Verrucomicrobia,2IVN1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TH3_k127_1635565_10	639030.JHVA01000001_gene3731	5.322e-35	141.0	2E9V0@1|root,3340V@2|Bacteria	2|Bacteria	S	carotenoid biosynthetic process	crtO	-	-	ko:K10212	ko00906,map00906	-	R07656	RC00041	ko00000,ko00001,ko01000	-	-	-	-
TH3_k127_1635565_7	204669.Acid345_2517	3.497e-72	252.0	COG3809@1|root,COG3809@2|Bacteria,3Y803@57723|Acidobacteria	57723|Acidobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zf-TFIIB
TH3_k127_1635565_2	452637.Oter_1792	3.155e-174	561.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_1635565_6	497964.CfE428DRAFT_5469	1.976e-78	279.0	COG2067@1|root,COG2067@2|Bacteria,46SR3@74201|Verrucomicrobia	74201|Verrucomicrobia	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
TH3_k127_1635565_13	1173026.Glo7428_2961	2.483e-16	91.0	COG3240@1|root,COG3240@2|Bacteria,1FZV1@1117|Cyanobacteria	1117|Cyanobacteria	I	Phospholipase lecithinase hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
TH3_k127_1635565_3	452637.Oter_0935	2.637e-153	494.0	COG0042@1|root,COG0042@2|Bacteria,46TCT@74201|Verrucomicrobia,3K895@414999|Opitutae	414999|Opitutae	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
TH3_k127_1635565_8	1297617.JPJD01000047_gene1362	1.047e-50	192.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,268EW@186813|unclassified Clostridiales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
TH3_k127_1635565_15	384616.Pisl_0649	5.072e-08	57.0	COG0314@1|root,COG1977@1|root,arCOG00534@2157|Archaea,arCOG00536@2157|Archaea,2XQRK@28889|Crenarchaeota	28889|Crenarchaeota	H	PFAM molybdopterin biosynthesis MoaE	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
TH3_k127_1635565_11	1121957.ATVL01000011_gene3577	5.119e-27	115.0	COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,47QJT@768503|Cytophagia	976|Bacteroidetes	H	Molybdopterin converting factor, large subunit	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
TH3_k127_1635565_0	497964.CfE428DRAFT_3486	0.0	1713.0	COG1038@1|root,COG1038@2|Bacteria,46S8N@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Conserved carboxylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
TH3_k127_1651644_4	452637.Oter_4517	2.265e-63	233.0	COG0673@1|root,COG0673@2|Bacteria,46UJR@74201|Verrucomicrobia,3K94Y@414999|Opitutae	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_1651644_0	243090.RB8979	1.38e-178	575.0	COG1760@1|root,COG1760@2|Bacteria	2|Bacteria	E	l-serine dehydratase	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
TH3_k127_1651644_5	1408813.AYMG01000036_gene3246	8.776e-61	215.0	COG0526@1|root,COG0526@2|Bacteria,4PIWE@976|Bacteroidetes,1IYSU@117747|Sphingobacteriia	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1651644_3	1521187.JPIM01000083_gene3839	2.277e-74	265.0	COG0153@1|root,COG0153@2|Bacteria,2G6CE@200795|Chloroflexi,375CJ@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
TH3_k127_1651644_8	426716.JOAJ01000004_gene3022	4.708e-24	104.0	COG2154@1|root,COG2154@2|Bacteria,2IKXR@201174|Actinobacteria,4G30U@85025|Nocardiaceae	201174|Actinobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
TH3_k127_1651644_9	1048339.KB913029_gene1929	3.756e-20	101.0	2E37T@1|root,32Y7G@2|Bacteria,2HKTZ@201174|Actinobacteria,4EWSP@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
TH3_k127_1651644_11	452637.Oter_0732	5.936e-10	68.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	ko:K18481	-	M00670	-	-	ko00000,ko00002,ko02000	3.A.1.27.4,3.A.1.27.5	-	-	DUF2510,FHA,RDD
TH3_k127_1651644_13	1303518.CCALI_02493	3.93e-06	59.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_1651644_12	1869.MB27_39975	7.387e-07	62.0	2EGCD@1|root,33A46@2|Bacteria,2HUKV@201174|Actinobacteria,4DFF1@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
TH3_k127_1651644_2	497964.CfE428DRAFT_2629	4.424e-77	271.0	COG0547@1|root,COG0547@2|Bacteria,46SQA@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
TH3_k127_1651644_1	204669.Acid345_4092	1.861e-82	286.0	COG0009@1|root,COG0009@2|Bacteria,3Y3VW@57723|Acidobacteria,2JHTT@204432|Acidobacteriia	204432|Acidobacteriia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
TH3_k127_1651644_6	452637.Oter_0025	8.232e-45	181.0	COG1538@1|root,COG1538@2|Bacteria,46VZS@74201|Verrucomicrobia,3K7CV@414999|Opitutae	414999|Opitutae	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TH3_k127_1651644_7	944479.JQLX01000016_gene325	2.226e-28	120.0	COG2050@1|root,COG2050@2|Bacteria,1N8F8@1224|Proteobacteria,42V78@68525|delta/epsilon subdivisions,2WRBA@28221|Deltaproteobacteria,2M7BC@213113|Desulfurellales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
TH3_k127_1651644_10	497964.CfE428DRAFT_6300	3.809e-20	92.0	COG1216@1|root,COG3250@1|root,COG1216@2|Bacteria,COG3250@2|Bacteria,46SAC@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_72,Glycos_transf_2
TH3_k127_1671563_0	1174528.JH992898_gene4971	1.173e-134	434.0	COG0826@1|root,COG0826@2|Bacteria,1G3NG@1117|Cyanobacteria,1JGWD@1189|Stigonemataceae	1117|Cyanobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32,Peptidase_U32_C
TH3_k127_1671563_14	357808.RoseRS_2451	4.527e-06	60.0	COG4870@1|root,COG4932@1|root,COG5513@1|root,COG4870@2|Bacteria,COG4932@2|Bacteria,COG5513@2|Bacteria,2GA24@200795|Chloroflexi,377PH@32061|Chloroflexia	2|Bacteria	MO	Carboxypeptidase regulatory-like domain	-	-	3.4.22.15	ko:K01365,ko:K02030,ko:K14475	ko04140,ko04142,ko04145,ko04210,ko04612,ko05143,ko05205,ko05323,ko05418,map04140,map04142,map04145,map04210,map04612,map05143,map05205,map05323,map05418	M00236	-	-	ko00000,ko00001,ko00002,ko00537,ko01000,ko01002,ko02000,ko03110	3.A.1.3	-	-	CarboxypepD_reg,Inhibitor_I42,Peptidase_C1
TH3_k127_1671563_4	316067.Geob_0443	1.269e-76	269.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria,43SZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
TH3_k127_1671563_7	481448.Minf_0292	2.058e-59	217.0	COG0760@1|root,COG0760@2|Bacteria,46SU4@74201|Verrucomicrobia,37G1D@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
TH3_k127_1671563_10	1395587.P364_0100735	1.68e-31	136.0	COG1409@1|root,COG1409@2|Bacteria,1V574@1239|Firmicutes,4HW52@91061|Bacilli,26S57@186822|Paenibacillaceae	91061|Bacilli	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
TH3_k127_1671563_11	926551.KB900703_gene1072	9.18e-18	95.0	COG4124@1|root,COG4124@2|Bacteria,4NEZG@976|Bacteroidetes,1HYFM@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Glyco_hydro_26
TH3_k127_1671563_6	1396418.BATQ01000083_gene1173	7.832e-61	237.0	COG0438@1|root,COG0438@2|Bacteria,46ZHN@74201|Verrucomicrobia,2IUVI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TH3_k127_1671563_8	497964.CfE428DRAFT_0084	1.134e-58	230.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
TH3_k127_1671563_13	5341.XP_007326237.1	6.841e-08	62.0	2CYVH@1|root,2S6PS@2759|Eukaryota,39RW6@33154|Opisthokonta,3NZFC@4751|Fungi,3V2QR@5204|Basidiomycota,227D7@155619|Agaricomycetes,3W5S1@5338|Agaricales	4751|Fungi	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
TH3_k127_1671563_9	452637.Oter_4020	1.546e-34	138.0	COG0703@1|root,COG0703@2|Bacteria,46YZV@74201|Verrucomicrobia,3K80S@414999|Opitutae	414999|Opitutae	H	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
TH3_k127_1671563_2	497964.CfE428DRAFT_4021	1.576e-104	357.0	COG1600@1|root,COG1600@2|Bacteria,46SDV@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
TH3_k127_1671563_3	926550.CLDAP_11070	4.208e-103	345.0	COG0444@1|root,COG0444@2|Bacteria,2G5PT@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
TH3_k127_1671563_12	1996.JOFO01000032_gene1329	9.773e-09	62.0	2ER32@1|root,33INP@2|Bacteria,2IPCY@201174|Actinobacteria,4EPID@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4259
TH3_k127_1671563_1	1293054.HSACCH_00337	2.246e-128	417.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WAI0@53433|Halanaerobiales	186801|Clostridia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain	appF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
TH3_k127_1671563_5	395495.Lcho_3430	3.604e-71	258.0	COG3210@1|root,COG5295@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria,1MXIP@1224|Proteobacteria,2VJ6Y@28216|Betaproteobacteria,1KKK5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	UW	haemagglutination activity domain	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Haemagg_act
TH3_k127_1708285_4	935948.KE386495_gene2110	1.202e-37	144.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,42GS3@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
TH3_k127_1708285_5	382464.ABSI01000010_gene3682	1.82e-18	97.0	COG1459@1|root,COG1459@2|Bacteria	2|Bacteria	U	protein transport across the cell outer membrane	pilC	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
TH3_k127_1708285_3	756067.MicvaDRAFT_0417	4.231e-106	372.0	COG1305@1|root,COG1305@2|Bacteria,1G1YY@1117|Cyanobacteria,1HA69@1150|Oscillatoriales	1117|Cyanobacteria	E	SMART Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
TH3_k127_1708285_2	56107.Cylst_0588	1.6e-119	399.0	COG1721@1|root,COG1721@2|Bacteria,1G1ZM@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TH3_k127_1708285_1	179408.Osc7112_2512	1.309e-135	439.0	COG0714@1|root,COG0714@2|Bacteria,1G0WS@1117|Cyanobacteria,1H9JV@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TH3_k127_1708285_0	1313304.CALK_1497	2.04e-140	457.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TH3_k127_1708285_7	1123278.KB893603_gene1858	2.133e-05	50.0	COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes,47K8X@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TH3_k127_1708285_6	1384066.JAGT01000001_gene1839	1.402e-16	81.0	COG1401@1|root,COG1401@2|Bacteria,1TPIP@1239|Firmicutes,249RD@186801|Clostridia,3WKMD@541000|Ruminococcaceae	186801|Clostridia	V	AAA domain (dynein-related subfamily)	-	-	-	ko:K07452	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5
TH3_k127_1732961_8	1454004.AW11_00388	0.0003438	43.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,2VKSZ@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
TH3_k127_1732961_4	1443122.Z958_01335	7.179e-64	228.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,36F30@31979|Clostridiaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	fldI	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
TH3_k127_1732961_3	247490.KSU1_C0461	5.627e-66	240.0	COG1775@1|root,COG1924@1|root,COG1775@2|Bacteria,COG1924@2|Bacteria,2J22H@203682|Planctomycetes	203682|Planctomycetes	EI	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,HGD-D
TH3_k127_1732961_7	1097668.BYI23_C012290	1.796e-22	102.0	COG2149@1|root,COG2149@2|Bacteria,1N8RW@1224|Proteobacteria,2VYKE@28216|Betaproteobacteria,1K9CA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
TH3_k127_1732961_5	1123368.AUIS01000004_gene187	5.165e-35	145.0	arCOG10317@1|root,2Z7VW@2|Bacteria,1RGUS@1224|Proteobacteria,1S5VW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1732961_9	1500281.JQKZ01000022_gene837	0.0005687	52.0	COG3637@1|root,COG3637@2|Bacteria,4PKKK@976|Bacteroidetes,1HYEJ@117743|Flavobacteriia,3ZP50@59732|Chryseobacterium	976|Bacteroidetes	M	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
TH3_k127_1732961_6	247639.MGP2080_02111	3.519e-31	132.0	COG2067@1|root,COG2067@2|Bacteria,1NDQA@1224|Proteobacteria,1TIWZ@1236|Gammaproteobacteria,1JBA2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1732961_2	497964.CfE428DRAFT_5778	3.849e-105	351.0	28HK0@1|root,2Z7V0@2|Bacteria,46TSH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
TH3_k127_1732961_1	1304885.AUEY01000019_gene1169	2.283e-141	474.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
TH3_k127_1732961_0	1366050.N234_35005	2.65e-203	642.0	COG4320@1|root,COG4320@2|Bacteria,1N6EW@1224|Proteobacteria,2VN9A@28216|Betaproteobacteria,1K2DQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
TH3_k127_178631_2	313628.LNTAR_00920	1.614e-94	332.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
TH3_k127_178631_0	742727.HMPREF9447_01794	3.67e-204	664.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,2FRKH@200643|Bacteroidia,4ARGS@815|Bacteroidaceae	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
TH3_k127_178631_3	1121957.ATVL01000009_gene1157	2.423e-42	172.0	COG3940@1|root,COG3940@2|Bacteria,4PMI7@976|Bacteroidetes,47YEP@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
TH3_k127_178631_1	349521.HCH_01563	9.449e-122	397.0	COG0657@1|root,COG0657@2|Bacteria,1R4AU@1224|Proteobacteria,1RQMN@1236|Gammaproteobacteria,1XR8Q@135619|Oceanospirillales	135619|Oceanospirillales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
TH3_k127_178631_4	497964.CfE428DRAFT_0023	1.079e-13	76.0	2EY4V@1|root,33RDN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1811232_13	1347086.CCBA010000009_gene1327	3.531e-31	143.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,Abhydrolase_6,DLH,Peptidase_S9
TH3_k127_1811232_7	485917.Phep_0331	3.113e-93	343.0	2AF40@1|root,3152Q@2|Bacteria,4P1UF@976|Bacteroidetes,1IX0U@117747|Sphingobacteriia	976|Bacteroidetes	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
TH3_k127_1811232_4	344747.PM8797T_17834	3.084e-121	404.0	COG3356@1|root,COG3356@2|Bacteria,2IX5S@203682|Planctomycetes	203682|Planctomycetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
TH3_k127_1811232_11	344747.PM8797T_30449	1.582e-47	185.0	294P7@1|root,2ZS2I@2|Bacteria,2J4KK@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1811232_8	118168.MC7420_2493	1.206e-78	282.0	COG1404@1|root,COG2931@1|root,COG4932@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1G04D@1117|Cyanobacteria,1H779@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,Peptidase_S8,SdrD_B
TH3_k127_1811232_1	1123242.JH636435_gene2020	8.23e-271	842.0	COG2407@1|root,COG2407@2|Bacteria,2IXT8@203682|Planctomycetes	203682|Planctomycetes	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1811232_16	926566.Terro_1693	5.692e-17	88.0	COG2823@1|root,COG2823@2|Bacteria,3Y4FV@57723|Acidobacteria,2JJ5I@204432|Acidobacteriia	204432|Acidobacteriia	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
TH3_k127_1811232_3	1304885.AUEY01000019_gene1169	1.136e-135	457.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
TH3_k127_1811232_5	497964.CfE428DRAFT_5778	2.283e-102	345.0	28HK0@1|root,2Z7V0@2|Bacteria,46TSH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
TH3_k127_1811232_10	690850.Desaf_1399	4.018e-50	199.0	COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,43ESD@68525|delta/epsilon subdivisions,2X9MI@28221|Deltaproteobacteria,2MF6N@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
TH3_k127_1811232_6	243233.MCA1632	6.26e-102	363.0	COG1196@1|root,COG3264@1|root,COG1196@2|Bacteria,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1XE6E@135618|Methylococcales	135618|Methylococcales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
TH3_k127_1811232_18	1232410.KI421421_gene3334	1.964e-11	75.0	2DT2H@1|root,33IDP@2|Bacteria,1NXAG@1224|Proteobacteria,430YG@68525|delta/epsilon subdivisions,2WVZY@28221|Deltaproteobacteria,43VAJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
TH3_k127_1811232_9	686340.Metal_2200	5.634e-54	208.0	2C6BE@1|root,32XBJ@2|Bacteria,1NB89@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1811232_20	670307.HYPDE_29893	1.086e-05	54.0	2FH9D@1|root,3493Q@2|Bacteria,1ND9G@1224|Proteobacteria,2UJ2Y@28211|Alphaproteobacteria,3N997@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
TH3_k127_1811232_21	935567.JAES01000002_gene626	1.79e-05	51.0	2EGKD@1|root,33ACM@2|Bacteria,1NAVJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1811232_14	1499967.BAYZ01000088_gene5060	6.212e-28	120.0	COG2189@1|root,COG2189@2|Bacteria,2NP0F@2323|unclassified Bacteria	2|Bacteria	L	PFAM DNA methylase N-4 N-6	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
TH3_k127_1811232_19	443254.Marpi_0296	8.045e-08	56.0	COG1715@1|root,COG2189@1|root,COG1715@2|Bacteria,COG2189@2|Bacteria	2|Bacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571,ko:K07316,ko:K07448	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5,Mrr_N,Mrr_cat,N6_N4_Mtase
TH3_k127_1811232_12	398767.Glov_2515	2.259e-41	160.0	2DGUS@1|root,32U80@2|Bacteria,1MZK3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1811232_17	1112212.JH584235_gene3224	2.34e-12	73.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TRE4@28211|Alphaproteobacteria,2K22C@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat,N6_N4_Mtase
TH3_k127_1811232_15	1112204.GPOL_c26570	1.606e-26	113.0	COG2189@1|root,COG2189@2|Bacteria,2I8FH@201174|Actinobacteria	201174|Actinobacteria	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
TH3_k127_1811232_0	521674.Plim_0789	0.0	1000.0	COG3119@1|root,COG3119@2|Bacteria,2IXNZ@203682|Planctomycetes	203682|Planctomycetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
TH3_k127_1811232_2	83332.Rv0663	2.424e-167	531.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,233CA@1762|Mycobacteriaceae	201174|Actinobacteria	P	thought to play an important role in the mineralization of sulfates catalytic activity a phenol sulfate H2O a phenol sulfate	atsD	GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008484,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043167,GO:0043169,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097708,GO:0099503,GO:1901135,GO:1901564,GO:1903509	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
TH3_k127_1833857_10	933262.AXAM01000130_gene757	1.13e-26	111.0	COG1598@1|root,COG1598@2|Bacteria,1P1K3@1224|Proteobacteria,431VD@68525|delta/epsilon subdivisions,2WWWI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1833857_11	388467.A19Y_4225	7.774e-23	99.0	2CIXY@1|root,338DR@2|Bacteria,1G934@1117|Cyanobacteria,1HDGE@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1833857_13	443143.GM18_2349	2.551e-18	89.0	COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,42TER@68525|delta/epsilon subdivisions,2WPKW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Thioesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
TH3_k127_1833857_5	671143.DAMO_2922	4.327e-72	257.0	COG1562@1|root,COG1562@2|Bacteria,2NQ18@2323|unclassified Bacteria	2|Bacteria	I	Squalene/phytoene synthase	crtB	GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576	2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99	ko:K00801,ko:K02291,ko:K10208	ko00100,ko00906,ko00909,ko01062,ko01100,ko01110,ko01130,map00100,map00906,map00909,map01062,map01100,map01110,map01130	M00097	R00702,R02065,R02872,R04218,R06223,R07270,R07652,R09793,R10177	RC00362,RC00796,RC01101,RC02839,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
TH3_k127_1833857_2	1396418.BATQ01000019_gene5009	5.382e-160	515.0	COG0019@1|root,COG0019@2|Bacteria,46SC5@74201|Verrucomicrobia,2ITWM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TH3_k127_1833857_14	1403819.BATR01000031_gene994	6.007e-07	57.0	2EMM1@1|root,33F9E@2|Bacteria,46TBT@74201|Verrucomicrobia,2IUX2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1833857_6	325452.fgenesh_scip_prom.46568.7654	3.228e-67	231.0	COG0318@1|root,COG0590@1|root,KOG1018@2759|Eukaryota,KOG1176@2759|Eukaryota,3Q9PC@4776|Peronosporales	4776|Peronosporales	I	AMP-binding enzyme C-terminal domain	-	-	-	ko:K18660	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
TH3_k127_1833857_1	497964.CfE428DRAFT_6179	3.576e-171	561.0	COG3875@1|root,COG3875@2|Bacteria,46TVY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
TH3_k127_1833857_4	768671.ThimaDRAFT_3418	8.019e-78	271.0	COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,1T2RP@1236|Gammaproteobacteria,1WXRA@135613|Chromatiales	135613|Chromatiales	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TH3_k127_1833857_3	497964.CfE428DRAFT_5037	3.561e-141	462.0	COG1454@1|root,COG1454@2|Bacteria,46TD9@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
TH3_k127_1833857_12	1120971.AUCA01000003_gene1386	6.285e-22	100.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,27A9H@186823|Alicyclobacillaceae	91061|Bacilli	K	helix_turn_helix gluconate operon transcriptional repressor	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
TH3_k127_1833857_7	344747.PM8797T_11666	4.859e-56	208.0	COG1131@1|root,COG1131@2|Bacteria,2IY79@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_1833857_9	307480.IW16_23585	6.135e-28	132.0	COG5184@1|root,COG5184@2|Bacteria,4NIP4@976|Bacteroidetes,1IIHQ@117743|Flavobacteriia,3ZNMC@59732|Chryseobacterium	976|Bacteroidetes	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,RCC1
TH3_k127_1833857_0	497964.CfE428DRAFT_5035	5.918e-244	765.0	COG1012@1|root,COG1012@2|Bacteria,46UJM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
TH3_k127_1833857_8	1121441.AUCX01000010_gene104	4.865e-31	125.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,2M8UQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_3_2
TH3_k127_1855605_3	661478.OP10G_0266	1.087e-13	77.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_1855605_2	1429851.X548_02885	1.849e-20	108.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,1T1MJ@1236|Gammaproteobacteria,1X4X8@135614|Xanthomonadales	135614|Xanthomonadales	U	Autotransporter beta-domain	yapH	-	-	-	-	-	-	-	-	-	-	-	ESPR,PATR
TH3_k127_1855605_1	485918.Cpin_3102	5.583e-58	210.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1ITQW@117747|Sphingobacteriia	976|Bacteroidetes	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_1855605_0	1403819.BATR01000125_gene4494	3.635e-173	580.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia,2IV8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
TH3_k127_1855605_4	596324.TREVI0001_1041	1.714e-10	75.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Collagen,DUF4347,PPC,RHS_repeat,SdrD_B,VWD
TH3_k127_1861453_2	452637.Oter_0253	8.059e-147	474.0	COG1454@1|root,COG1454@2|Bacteria	2|Bacteria	C	hydroxyacid-oxoacid transhydrogenase activity	CT0951	-	1.1.1.1,4.3.3.7	ko:K00001,ko:K01714	ko00010,ko00071,ko00261,ko00300,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,ko01230,map00010,map00071,map00261,map00300,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220,map01230	M00016,M00525,M00526,M00527	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10147	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	Fe-ADH
TH3_k127_1861453_1	342610.Patl_0129	6.683e-192	616.0	COG0591@1|root,COG0591@2|Bacteria,1PNHU@1224|Proteobacteria,1S0S6@1236|Gammaproteobacteria,2Q4RI@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
TH3_k127_1861453_6	794903.OPIT5_04755	7.427e-120	394.0	COG2152@1|root,COG2152@2|Bacteria,46YKJ@74201|Verrucomicrobia,3K8SE@414999|Opitutae	2|Bacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.339,2.4.1.340	ko:K20885	-	-	R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
TH3_k127_1861453_4	452637.Oter_3888	5.19e-129	416.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
TH3_k127_1861453_12	794903.OPIT5_18130	1.666e-43	162.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
TH3_k127_1861453_3	452637.Oter_3889	8.157e-147	471.0	COG2025@1|root,COG2025@2|Bacteria	2|Bacteria	C	fatty acid beta-oxidation using acyl-CoA dehydrogenase	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	Acyl-CoA_dh_1,ETF,ETF_alpha
TH3_k127_1861453_0	76114.ebA2970	5.013e-295	946.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VI87@28216|Betaproteobacteria,2KVBJ@206389|Rhodocyclales	206389|Rhodocyclales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
TH3_k127_1861453_17	1121015.N789_03170	6.422e-12	78.0	COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria,1RS2N@1236|Gammaproteobacteria,1X2Z1@135614|Xanthomonadales	135614|Xanthomonadales	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
TH3_k127_1861453_20	945713.IALB_2117	0.0002516	55.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C10,Phage-tail_3,Prophage_tail,SLH
TH3_k127_1861453_15	1123278.KB893445_gene1153	1.82e-18	101.0	COG1577@1|root,COG1874@1|root,COG2374@1|root,COG3210@1|root,COG4625@1|root,COG4886@1|root,COG1577@2|Bacteria,COG1874@2|Bacteria,COG2374@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	mvaK2	-	2.7.1.36,2.7.4.2,3.1.3.5,3.2.1.97,3.4.21.72,4.2.2.23	ko:K00869,ko:K00938,ko:K01081,ko:K01347,ko:K07004,ko:K17624,ko:K18195,ko:K21449	ko00230,ko00240,ko00760,ko00900,ko01100,ko01110,ko01130,ko04146,map00230,map00240,map00760,map00900,map01100,map01110,map01130,map04146	M00095	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02245,R02323,R02719,R03245,R03346	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko02044	1.B.12.3,1.B.40.2	GH101,PL4	-	CBM-like,GHMP_kinases_C,GHMP_kinases_N,HtaA,NPCBM,RhgB_N,fn3_3
TH3_k127_1861453_7	349741.Amuc_1584	3.819e-112	378.0	COG1459@1|root,COG1459@2|Bacteria,46U60@74201|Verrucomicrobia,2IWMJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
TH3_k127_1861453_19	452637.Oter_0312	2.114e-06	63.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
TH3_k127_1861453_14	641524.ADICYQ_5597	1.123e-18	104.0	COG5337@1|root,COG5337@2|Bacteria,4NEH2@976|Bacteroidetes,47PGS@768503|Cytophagia	976|Bacteroidetes	M	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
TH3_k127_1861453_5	1396141.BATP01000020_gene108	4.546e-124	452.0	COG2312@1|root,COG4870@1|root,COG2312@2|Bacteria,COG4870@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
TH3_k127_1861453_16	324602.Caur_0211	1.855e-15	93.0	COG1319@1|root,COG3391@1|root,COG1319@2|Bacteria,COG3391@2|Bacteria,2GA7F@200795|Chloroflexi,376QS@32061|Chloroflexia	32061|Chloroflexia	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1861453_10	497964.CfE428DRAFT_2594	1.265e-61	222.0	COG2138@1|root,COG2138@2|Bacteria,46SPE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CbiX	-	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
TH3_k127_1861453_9	234267.Acid_7405	2.942e-62	224.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
TH3_k127_1861453_18	344747.PM8797T_17187	6.99e-07	62.0	COG1621@1|root,COG1621@2|Bacteria,2IY26@203682|Planctomycetes	203682|Planctomycetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1861453_11	1123508.JH636450_gene7204	1.316e-61	233.0	COG0673@1|root,COG0673@2|Bacteria,2IXVF@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_1861453_8	326297.Sama_0297	6.397e-112	375.0	COG3828@1|root,COG3828@2|Bacteria,1QVR0@1224|Proteobacteria,1SN58@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glycosyl hydrolase family 99	-	-	3.2.1.130	ko:K15538	-	-	-	-	ko00000,ko01000	-	GH99	-	Glyco_hydro_99
TH3_k127_1892053_8	675815.VOA_002855	4.192e-56	209.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1XSM4@135623|Vibrionales	135623|Vibrionales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
TH3_k127_1892053_5	497964.CfE428DRAFT_4315	7.866e-84	291.0	COG0373@1|root,COG0373@2|Bacteria,46SMQ@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,Shikimate_DH
TH3_k127_1892053_12	1156937.MFUM_930026	9.993e-37	149.0	COG4137@1|root,COG4137@2|Bacteria,46T0T@74201|Verrucomicrobia,37GN8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
TH3_k127_1892053_2	497964.CfE428DRAFT_2029	9.753e-101	338.0	COG0777@1|root,COG0777@2|Bacteria,46SI0@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
TH3_k127_1892053_10	1396141.BATP01000058_gene1952	4.333e-44	172.0	COG1040@1|root,COG1040@2|Bacteria,46T0D@74201|Verrucomicrobia,2IUGQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
TH3_k127_1892053_11	592028.GCWU000321_00198	1.281e-40	161.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H2BH@909932|Negativicutes	909932|Negativicutes	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
TH3_k127_1892053_6	452637.Oter_2645	1.262e-73	257.0	COG2866@1|root,COG2866@2|Bacteria,46T00@74201|Verrucomicrobia,3K83I@414999|Opitutae	414999|Opitutae	E	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
TH3_k127_1892053_4	316067.Geob_3008	4.523e-90	309.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42NGR@68525|delta/epsilon subdivisions,2WIMA@28221|Deltaproteobacteria,43TMT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6,5.4.99.58	ko:K01012,ko:K16180	ko00300,ko00780,ko01100,ko01120,map00300,map00780,map01100,map01120	M00123,M00573,M00577	R01078,R10010	RC00441,RC02995	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1582	BATS,Radical_SAM
TH3_k127_1892053_3	344747.PM8797T_20084	7.475e-97	346.0	COG3391@1|root,COG3391@2|Bacteria,2IY8U@203682|Planctomycetes	203682|Planctomycetes	M	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TH3_k127_1892053_7	543728.Vapar_2851	1.9e-58	205.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,2WBQC@28216|Betaproteobacteria,4AI59@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
TH3_k127_1892053_13	1403819.BATR01000182_gene6270	3.178e-27	129.0	COG0457@1|root,COG1196@1|root,COG0457@2|Bacteria,COG1196@2|Bacteria,46T1H@74201|Verrucomicrobia,2IUR7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
TH3_k127_1892053_14	56107.Cylst_5717	1.232e-14	87.0	COG1413@1|root,COG1672@1|root,COG1413@2|Bacteria,COG1672@2|Bacteria,1G2R4@1117|Cyanobacteria,1HMQH@1161|Nostocales	1117|Cyanobacteria	CT	HEAT repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
TH3_k127_1892053_15	382464.ABSI01000005_gene1329	7.226e-09	61.0	COG1758@1|root,COG1758@2|Bacteria,46W29@74201|Verrucomicrobia,2IUQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	RNA polymerase activity	-	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
TH3_k127_1892053_9	945713.IALB_1744	4.814e-45	168.0	COG0691@1|root,COG0691@2|Bacteria	2|Bacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
TH3_k127_1892053_1	794903.OPIT5_26245	4.234e-188	613.0	COG4796@1|root,COG4796@2|Bacteria,46Y4X@74201|Verrucomicrobia,3K8XV@414999|Opitutae	414999|Opitutae	U	Bacterial type II and III secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	Secretin
TH3_k127_1892053_16	1210884.HG799463_gene10210	8.237e-09	68.0	COG4972@1|root,COG4972@2|Bacteria,2IWXB@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
TH3_k127_1892053_17	794903.OPIT5_26235	0.0002384	53.0	2A3EY@1|root,31MUJ@2|Bacteria,46X6D@74201|Verrucomicrobia,3K9KW@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1892053_0	794903.OPIT5_26225	1.043e-195	626.0	COG2804@1|root,COG2804@2|Bacteria,46XZ0@74201|Verrucomicrobia,3K8NA@414999|Opitutae	414999|Opitutae	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
TH3_k127_1892392_8	452637.Oter_2422	1.587e-67	236.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
TH3_k127_1892392_0	1396141.BATP01000060_gene4560	1.167e-232	752.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
TH3_k127_1892392_15	43989.cce_4844	2.546e-06	58.0	2A2DT@1|root,30QQT@2|Bacteria,1GM8B@1117|Cyanobacteria,3KJT1@43988|Cyanothece	1117|Cyanobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
TH3_k127_1892392_13	349741.Amuc_0423	6.43e-21	99.0	COG0054@1|root,COG0054@2|Bacteria,46T5S@74201|Verrucomicrobia,2IUDV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
TH3_k127_1892392_1	497964.CfE428DRAFT_4667	1.5e-179	572.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,46S5K@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
TH3_k127_1892392_10	639030.JHVA01000001_gene2022	6.149e-42	164.0	COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria,2JJME@204432|Acidobacteriia	204432|Acidobacteriia	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
TH3_k127_1892392_9	478741.JAFS01000001_gene1116	2.292e-66	244.0	COG1612@1|root,COG1612@2|Bacteria,46T3F@74201|Verrucomicrobia,37G83@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
TH3_k127_1892392_6	234267.Acid_4382	7.255e-76	265.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria	57723|Acidobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
TH3_k127_1892392_2	234267.Acid_5590	5.986e-161	527.0	COG0843@1|root,COG0843@2|Bacteria,3Y2NS@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
TH3_k127_1892392_5	481448.Minf_1950	1.248e-85	291.0	COG1845@1|root,COG1845@2|Bacteria,46SRD@74201|Verrucomicrobia,37FZZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c oxidase subunit III	cyoC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
TH3_k127_1892392_14	1396141.BATP01000045_gene1834	4.483e-08	60.0	2DR0H@1|root,339NS@2|Bacteria,46ZIA@74201|Verrucomicrobia,2IUYZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
TH3_k127_1892392_7	497964.CfE428DRAFT_2235	7.857e-69	242.0	COG1622@1|root,COG1622@2|Bacteria,46SPQ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
TH3_k127_1892392_12	1123508.JH636448_gene7577	2.296e-30	128.0	COG1999@1|root,COG1999@2|Bacteria,2IZH2@203682|Planctomycetes	203682|Planctomycetes	S	SCO1/SenC	-	-	-	ko:K07152,ko:K08976	-	-	-	-	ko00000,ko03029	-	-	-	DUF420,SCO1-SenC
TH3_k127_1892392_11	1279038.KB907352_gene2224	2.78e-31	128.0	COG2322@1|root,COG2322@2|Bacteria,1N3YI@1224|Proteobacteria,2UJ8D@28211|Alphaproteobacteria,2JX8I@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
TH3_k127_1892392_4	313612.L8106_20308	7.199e-86	296.0	COG4301@1|root,COG4301@2|Bacteria,1G4VW@1117|Cyanobacteria,1HF60@1150|Oscillatoriales	1117|Cyanobacteria	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
TH3_k127_1892392_3	533247.CRD_00431	2.334e-118	388.0	COG0294@1|root,COG0720@1|root,COG0294@2|Bacteria,COG0720@2|Bacteria,1GKBI@1117|Cyanobacteria,1HSIJ@1161|Nostocales	1117|Cyanobacteria	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
TH3_k127_1910470_11	497964.CfE428DRAFT_6232	3.201e-33	133.0	COG0745@1|root,COG0745@2|Bacteria,46W19@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TH3_k127_1910470_6	402777.KB235903_gene2363	5.782e-87	311.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1G1Z8@1117|Cyanobacteria,1H950@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
TH3_k127_1910470_21	452637.Oter_1439	6.235e-05	51.0	COG1544@1|root,COG1544@2|Bacteria,46WN8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
TH3_k127_1910470_5	373903.Hore_13580	8.317e-105	356.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3WC51@53433|Halanaerobiales	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
TH3_k127_1910470_9	330214.NIDE3859	2.196e-50	187.0	COG0071@1|root,COG0071@2|Bacteria,3J0TV@40117|Nitrospirae	40117|Nitrospirae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
TH3_k127_1910470_12	520709.F985_03132	7.778e-26	111.0	2EEQQ@1|root,338IE@2|Bacteria,1N816@1224|Proteobacteria,1SR3D@1236|Gammaproteobacteria,3NS16@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1910470_13	765914.ThisiDRAFT_1557	1.249e-17	85.0	2E3KF@1|root,32YIQ@2|Bacteria,1NC3P@1224|Proteobacteria,1SD8X@1236|Gammaproteobacteria,1WZDZ@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1910470_15	278957.ABEA03000005_gene4416	7.075e-17	81.0	2EK6E@1|root,33DWT@2|Bacteria,46ZJP@74201|Verrucomicrobia,3K8CQ@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF3185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
TH3_k127_1910470_18	1167006.UWK_00985	2.21e-14	74.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,2MPCB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1910470_3	794903.OPIT5_27315	6.393e-117	389.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	MA20_08125	-	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_trans_aux,MlaD
TH3_k127_1910470_7	794903.OPIT5_27320	7.584e-85	289.0	COG0767@1|root,COG0767@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
TH3_k127_1910470_19	1123276.KB893245_gene1757	8.07e-10	66.0	29Q3N@1|root,30B2B@2|Bacteria,4NPCV@976|Bacteroidetes,47Q0V@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1910470_17	443143.GM18_0916	1.145e-15	84.0	COG2133@1|root,COG4447@1|root,COG4733@1|root,COG2133@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,1PFCA@1224|Proteobacteria,42WUH@68525|delta/epsilon subdivisions,2WT3I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
TH3_k127_1910470_14	330214.NIDE0935	5.788e-17	89.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
TH3_k127_1910470_16	324925.Ppha_2361	4.34e-16	81.0	2E35S@1|root,32Y5P@2|Bacteria	2|Bacteria	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
TH3_k127_1910470_20	1267534.KB906754_gene3064	4.853e-06	51.0	2EFZF@1|root,339RM@2|Bacteria,3Y5X5@57723|Acidobacteria,2JK63@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1910470_4	794903.OPIT5_29540	1.687e-106	359.0	COG4585@1|root,COG4585@2|Bacteria,46TVJ@74201|Verrucomicrobia,3K9CA@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TH3_k127_1910470_8	1403819.BATR01000181_gene6249	2.237e-83	282.0	COG2197@1|root,COG2197@2|Bacteria,46UGC@74201|Verrucomicrobia,2IUI3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_1910470_0	880072.Desac_1063	2.06e-259	809.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MS34@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
TH3_k127_1910470_2	1123073.KB899241_gene3250	5.471e-146	472.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S0IS@1236|Gammaproteobacteria,1X4IQ@135614|Xanthomonadales	135614|Xanthomonadales	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TH3_k127_1910470_1	1232410.KI421421_gene3328	2.991e-211	666.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,43S64@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
TH3_k127_1910470_10	1288298.rosmuc_00470	9.236e-35	142.0	COG4238@1|root,COG4238@2|Bacteria,1RDE3@1224|Proteobacteria,2U7FF@28211|Alphaproteobacteria,46P9E@74030|Roseovarius	28211|Alphaproteobacteria	M	major outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1917706_1	314230.DSM3645_04800	1.121e-180	632.0	COG2373@1|root,COG2373@2|Bacteria,2IWRT@203682|Planctomycetes	203682|Planctomycetes	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
TH3_k127_1917706_8	456442.Mboo_0115	2.612e-22	110.0	COG1413@1|root,arCOG02966@2157|Archaea,2XSWS@28890|Euryarchaeota	28890|Euryarchaeota	C	PBS lyase	cpcE2	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS
TH3_k127_1917706_10	382464.ABSI01000010_gene3336	1.885e-09	69.0	COG3064@1|root,COG3064@2|Bacteria,46VZ5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1917706_7	481448.Minf_0919	5.412e-40	156.0	COG0811@1|root,COG0811@2|Bacteria,46T1R@74201|Verrucomicrobia,37GG9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
TH3_k127_1917706_9	1396418.BATQ01000003_gene1334	1.235e-11	75.0	COG0848@1|root,COG0848@2|Bacteria,46T7H@74201|Verrucomicrobia,2IUR9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
TH3_k127_1917706_3	497964.CfE428DRAFT_5395	3.469e-160	514.0	COG0136@1|root,COG0136@2|Bacteria,46S74@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
TH3_k127_1917706_4	1303518.CCALI_00393	3.166e-152	497.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,DUF1080,DUF4241
TH3_k127_1917706_2	1123242.JH636434_gene4648	2.944e-175	562.0	COG0673@1|root,COG0673@2|Bacteria,2IXDR@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_1917706_5	886293.Sinac_4629	1.496e-142	468.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_1917706_6	497964.CfE428DRAFT_3384	3.213e-138	442.0	COG0207@1|root,COG0207@2|Bacteria,46SCY@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
TH3_k127_1917706_0	1380394.JADL01000003_gene4962	1.638e-194	634.0	COG1216@1|root,COG3934@1|root,COG1216@2|Bacteria,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Cellulase,Glyco_hydro_2_C,Glycos_transf_2
TH3_k127_1931913_0	886293.Sinac_5601	4.415e-258	828.0	COG2010@1|root,COG2010@2|Bacteria,2J53S@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
TH3_k127_1931913_1	886293.Sinac_6954	6.416e-58	213.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TH3_k127_1932322_0	509635.N824_16950	3.326e-42	169.0	28MSZ@1|root,2ZB1A@2|Bacteria,4NHVN@976|Bacteroidetes	976|Bacteroidetes	S	GxGYxY sequence motif in domain of unknown function N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	GxGYxYP_C,GxGYxYP_N
TH3_k127_1932322_1	794903.OPIT5_09305	2.543e-11	75.0	COG2165@1|root,COG2165@2|Bacteria,46YH2@74201|Verrucomicrobia,3K9K1@414999|Opitutae	414999|Opitutae	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1932962_2	1121904.ARBP01000011_gene1418	8.9e-13	68.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,47K06@768503|Cytophagia	976|Bacteroidetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
TH3_k127_1932962_0	1123278.KB893598_gene2685	1.241e-37	166.0	COG3210@1|root,COG3391@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,4NTNN@976|Bacteroidetes,47K8B@768503|Cytophagia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP,SprB
TH3_k127_1932962_3	1464048.JNZS01000012_gene3465	1.345e-10	74.0	COG4099@1|root,COG4099@2|Bacteria,2HVY5@201174|Actinobacteria,4DI2H@85008|Micromonosporales	201174|Actinobacteria	S	phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1932962_1	498761.HM1_0137	2.188e-21	109.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
TH3_k127_1945692_8	192952.MM_1779	3.31e-73	252.0	COG1926@1|root,arCOG06847@2157|Archaea,2XWRW@28890|Euryarchaeota,2NABG@224756|Methanomicrobia	224756|Methanomicrobia	S	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
TH3_k127_1945692_4	497964.CfE428DRAFT_3666	4.147e-92	311.0	COG1409@1|root,COG1409@2|Bacteria,46TUP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
TH3_k127_1945692_13	583355.Caka_1102	2.309e-37	149.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
TH3_k127_1945692_9	497964.CfE428DRAFT_1729	8.788e-72	248.0	COG0122@1|root,COG0122@2|Bacteria,46V2J@74201|Verrucomicrobia	74201|Verrucomicrobia	L	endonuclease III	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
TH3_k127_1945692_11	497964.CfE428DRAFT_2483	6.467e-66	235.0	COG0697@1|root,COG0697@2|Bacteria,46SR7@74201|Verrucomicrobia	74201|Verrucomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TH3_k127_1945692_3	1300345.LF41_1322	5.951e-100	338.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1S5WE@1236|Gammaproteobacteria,1X3ZI@135614|Xanthomonadales	135614|Xanthomonadales	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TH3_k127_1945692_2	1499967.BAYZ01000171_gene5584	4.285e-125	410.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
TH3_k127_1945692_0	1123242.JH636435_gene793	7.666e-187	596.0	COG0415@1|root,COG0415@2|Bacteria,2IZKY@203682|Planctomycetes	203682|Planctomycetes	L	FAD binding domain of DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
TH3_k127_1945692_12	521674.Plim_2739	4.728e-60	220.0	COG0204@1|root,COG0204@2|Bacteria,2IZPB@203682|Planctomycetes	203682|Planctomycetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TH3_k127_1945692_1	344747.PM8797T_20643	5.798e-143	475.0	COG1520@1|root,COG1520@2|Bacteria,2IX2Z@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_1945692_15	595460.RRSWK_05296	2.955e-16	93.0	COG1012@1|root,COG1012@2|Bacteria,2IZ2G@203682|Planctomycetes	203682|Planctomycetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TH3_k127_1945692_6	497964.CfE428DRAFT_4839	2.244e-81	285.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TH3_k127_1945692_5	452637.Oter_1107	1.53e-84	291.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,46V45@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
TH3_k127_1945692_7	497964.CfE428DRAFT_2458	2.787e-81	277.0	COG4798@1|root,COG4798@2|Bacteria,46T4I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
TH3_k127_1945692_14	1265505.ATUG01000001_gene4678	2.683e-24	121.0	COG0584@1|root,COG1409@1|root,COG0584@2|Bacteria,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GDPD_2,Metallophos,Pur_ac_phosph_N
TH3_k127_1945692_17	380358.XALC_2323	0.0001815	45.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR3Q@1236|Gammaproteobacteria,1XCRD@135614|Xanthomonadales	135614|Xanthomonadales	L	Isxal7 transposase orfb protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
TH3_k127_1945692_10	663321.REG_1035	1.732e-67	234.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RMWW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
TH3_k127_1965451_3	861299.J421_5653	9.316e-114	389.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_1965451_2	1123242.JH636434_gene3154	4.862e-126	413.0	COG2159@1|root,COG2159@2|Bacteria,2J3RZ@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
TH3_k127_1965451_1	1123242.JH636435_gene772	1.965e-173	554.0	COG0477@1|root,COG2814@2|Bacteria,2J4VW@203682|Planctomycetes	1123242.JH636435_gene772|-	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1965451_6	234267.Acid_7405	9.072e-61	221.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
TH3_k127_1965451_5	616991.JPOO01000001_gene2853	5.951e-89	307.0	COG4409@1|root,COG4409@2|Bacteria,4PAPR@976|Bacteroidetes,1IF7B@117743|Flavobacteriia,23HKK@178469|Arenibacter	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TH3_k127_1965451_8	886293.Sinac_0556	2.497e-16	89.0	COG2165@1|root,COG2165@2|Bacteria,2IZ3B@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_1965451_7	1396141.BATP01000003_gene4864	3.5e-39	169.0	COG2273@1|root,COG3210@1|root,COG3533@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG5295@1|root,COG2273@2|Bacteria,COG3210@2|Bacteria,COG3533@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5295@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	2|Bacteria	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	oprH	-	3.2.1.4,3.2.1.73	ko:K01179,ko:K01216,ko:K02014,ko:K07004,ko:K15125,ko:K16087,ko:K21449	ko00500,ko01100,ko05133,map00500,map01100,map05133	-	R06200,R11307,R11308	-	ko00000,ko00001,ko00536,ko01000,ko02000	1.B.14,1.B.14.2,1.B.40.2	GH5,GH9	-	Glyco_hydro_16,HemolysinCabind,OMP_b-brl,fn3
TH3_k127_1965451_9	1463879.JOHP01000017_gene2377	3.635e-10	70.0	COG2207@1|root,COG2207@2|Bacteria,2GK7Q@201174|Actinobacteria	201174|Actinobacteria	K	Arac family	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
TH3_k127_1965451_4	886293.Sinac_0920	1.161e-107	365.0	COG0673@1|root,COG0673@2|Bacteria,2IWZW@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_1965451_0	583355.Caka_3117	6.263e-183	593.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Beta_helix,DUF1565
TH3_k127_1975670_28	1305735.JAFT01000005_gene2369	1.552e-18	93.0	COG1396@1|root,COG1396@2|Bacteria,1N8D1@1224|Proteobacteria,2U832@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
TH3_k127_1975670_18	1122169.AREN01000009_gene642	4.541e-97	331.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,1RNYG@1236|Gammaproteobacteria,1JFTD@118969|Legionellales	118969|Legionellales	S	Pfam:HipA_N	-	-	-	-	-	-	-	-	-	-	-	-	Couple_hipA,HipA_C
TH3_k127_1975670_31	1089550.ATTH01000002_gene84	2.257e-12	75.0	COG3000@1|root,COG3000@2|Bacteria,4NES7@976|Bacteroidetes	976|Bacteroidetes	I	sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
TH3_k127_1975670_9	1449126.JQKL01000012_gene3514	2.462e-134	437.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,267ZX@186813|unclassified Clostridiales	186801|Clostridia	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
TH3_k127_1975670_19	1121875.KB907550_gene801	6.986e-96	329.0	COG0684@1|root,COG0684@2|Bacteria,4NF3M@976|Bacteroidetes,1HYXI@117743|Flavobacteriia	976|Bacteroidetes	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
TH3_k127_1975670_1	1121904.ARBP01000009_gene4249	2.841e-183	584.0	COG4948@1|root,COG4948@2|Bacteria,4NI24@976|Bacteroidetes,47N24@768503|Cytophagia	976|Bacteroidetes	M	mandelate racemase muconate lactonizing	-	-	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
TH3_k127_1975670_17	497964.CfE428DRAFT_5266	1.126e-99	340.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_1975670_32	1096546.WYO_2614	4.792e-10	65.0	COG4453@1|root,COG4453@2|Bacteria,1PW0X@1224|Proteobacteria,2V2IS@28211|Alphaproteobacteria,1JYKH@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
TH3_k127_1975670_25	195250.CM001776_gene4007	5.685e-32	135.0	COG0454@1|root,COG0456@2|Bacteria,1GHNN@1117|Cyanobacteria,1H4EJ@1129|Synechococcus	1117|Cyanobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1975670_35	378753.KRH_07290	0.0003759	47.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,1WA7Y@1268|Micrococcaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,LZ_Tnp_IS481,rve,rve_3
TH3_k127_1975670_33	671065.MetMK1DRAFT_00016260	5.11e-09	68.0	COG0666@1|root,arCOG04004@2157|Archaea,2XS0N@28889|Crenarchaeota	28889|Crenarchaeota	S	ankyrin repeats	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4
TH3_k127_1975670_34	1173023.KE650771_gene2595	1.893e-05	50.0	COG2303@1|root,COG2303@2|Bacteria,1G2DQ@1117|Cyanobacteria,1JHUA@1189|Stigonemataceae	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
TH3_k127_1975670_11	497964.CfE428DRAFT_4366	6.276e-126	417.0	COG1520@1|root,COG1520@2|Bacteria,46TRS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_1975670_0	234267.Acid_3246	2.245e-183	587.0	COG0673@1|root,COG0673@2|Bacteria,3Y76D@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_1975670_12	886293.Sinac_7310	4.135e-117	384.0	COG1413@1|root,COG1413@2|Bacteria,2IYWU@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_1975670_29	349741.Amuc_1556	1.41e-12	72.0	COG0291@1|root,COG0291@2|Bacteria,46TCI@74201|Verrucomicrobia,2IUW5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L35	-	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
TH3_k127_1975670_24	794903.OPIT5_02620	1.119e-35	140.0	COG0292@1|root,COG0292@2|Bacteria,46SZW@74201|Verrucomicrobia,3K87I@414999|Opitutae	414999|Opitutae	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
TH3_k127_1975670_8	331869.BAL199_18073	3.577e-141	457.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2TSXG@28211|Alphaproteobacteria,4BRCX@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053,ko:K14274	ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02427,R02933,R03751	RC00537,RC00713,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
TH3_k127_1975670_2	1396141.BATP01000033_gene4259	1.133e-171	561.0	COG1200@1|root,COG1200@2|Bacteria,46TTC@74201|Verrucomicrobia,2ITXG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	RecG wedge domain	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
TH3_k127_1975670_13	886293.Sinac_4612	1.507e-110	363.0	2BZ6M@1|root,2Z7HW@2|Bacteria,2IXV4@203682|Planctomycetes	203682|Planctomycetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_1975670_3	234267.Acid_3343	1.726e-156	510.0	COG4948@1|root,COG4948@2|Bacteria,3Y61U@57723|Acidobacteria	57723|Acidobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
TH3_k127_1975670_21	1121875.KB907555_gene345	1.49e-83	292.0	COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,1HY0F@117743|Flavobacteriia	976|Bacteroidetes	S	Sodium bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
TH3_k127_1975670_14	314230.DSM3645_21427	5.178e-109	368.0	COG1387@1|root,COG2755@1|root,COG1387@2|Bacteria,COG2755@2|Bacteria,2IXFZ@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_1975670_6	240292.Ava_0681	3.43e-144	465.0	COG0667@1|root,COG0667@2|Bacteria,1G3RI@1117|Cyanobacteria,1HMNR@1161|Nostocales	1117|Cyanobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TH3_k127_1975670_4	1122176.KB903544_gene705	7.581e-151	489.0	COG0174@1|root,COG0174@2|Bacteria,4NHET@976|Bacteroidetes,1IPJ3@117747|Sphingobacteriia	976|Bacteroidetes	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
TH3_k127_1975670_5	395961.Cyan7425_1966	1.303e-150	490.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,3KGCF@43988|Cyanothece	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8	ko:K00128,ko:K00130,ko:K00135,ko:K00138,ko:K00146	ko00010,ko00053,ko00071,ko00250,ko00260,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00260,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135,M00555	R00264,R00631,R00710,R00711,R00713,R00714,R00904,R01752,R01986,R02401,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TH3_k127_1975670_27	478741.JAFS01000001_gene1530	9.861e-20	91.0	COG2127@1|root,COG2127@2|Bacteria,46T8N@74201|Verrucomicrobia,37GW2@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
TH3_k127_1975670_22	1156937.MFUM_270019	8.007e-83	280.0	COG2360@1|root,COG2360@2|Bacteria,46VHR@74201|Verrucomicrobia,37GDI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
TH3_k127_1975670_10	530564.Psta_0851	1.227e-128	419.0	COG0604@1|root,COG0604@2|Bacteria,2IXUI@203682|Planctomycetes	203682|Planctomycetes	C	COG0604 NADPH quinone reductase and related Zn-dependent	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
TH3_k127_1975670_20	1123508.JH636440_gene2839	4.981e-93	319.0	COG2304@1|root,COG2304@2|Bacteria,2IYXD@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
TH3_k127_1975670_23	497964.CfE428DRAFT_1718	4.713e-59	207.0	COG3558@1|root,COG3558@2|Bacteria,46VBZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
TH3_k127_1975670_7	497964.CfE428DRAFT_3635	1.031e-141	474.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,46S7F@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
TH3_k127_1975670_16	55529.EKX47288	1.371e-101	350.0	COG0144@1|root,KOG1122@2759|Eukaryota	2759|Eukaryota	J	rRNA (cytosine-C5-)-methyltransferase activity	-	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
TH3_k127_1975670_30	382464.ABSI01000007_gene4120	1.931e-12	74.0	2F78F@1|root,33ZPQ@2|Bacteria,46VT2@74201|Verrucomicrobia,2IURV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1975670_15	28072.Nos7524_0364	1.792e-102	339.0	COG0412@1|root,COG0412@2|Bacteria,1G4HV@1117|Cyanobacteria,1HMQR@1161|Nostocales	1117|Cyanobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
TH3_k127_1975670_26	867903.ThesuDRAFT_00317	4.116e-21	97.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3WCMZ@538999|Clostridiales incertae sedis	186801|Clostridia	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
TH3_k127_1985074_1	96561.Dole_1704	1.071e-16	94.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_1985074_0	498761.HM1_0137	1.971e-29	135.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
TH3_k127_199978_9	794903.OPIT5_19655	1.862e-41	163.0	COG0629@1|root,COG0629@2|Bacteria,46VZR@74201|Verrucomicrobia,3K80H@414999|Opitutae	414999|Opitutae	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
TH3_k127_199978_10	478741.JAFS01000001_gene1845	8.799e-12	69.0	COG0360@1|root,COG0360@2|Bacteria,46TBG@74201|Verrucomicrobia,37GXZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
TH3_k127_199978_8	111781.Lepto7376_3170	1.81e-49	183.0	COG0193@1|root,COG0193@2|Bacteria,1G0D0@1117|Cyanobacteria,1H70D@1150|Oscillatoriales	1117|Cyanobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
TH3_k127_199978_7	497964.CfE428DRAFT_1544	2.227e-55	204.0	COG1825@1|root,COG1825@2|Bacteria,46SZS@74201|Verrucomicrobia	74201|Verrucomicrobia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
TH3_k127_199978_3	1156937.MFUM_870060	6.498e-130	421.0	COG0462@1|root,COG0462@2|Bacteria,46SVH@74201|Verrucomicrobia,37GGN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
TH3_k127_199978_4	497964.CfE428DRAFT_4701	2.16e-116	389.0	COG0482@1|root,COG0482@2|Bacteria,46SQW@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
TH3_k127_199978_0	452637.Oter_2432	7.918e-259	807.0	COG0155@1|root,COG0155@2|Bacteria,46U85@74201|Verrucomicrobia,3K77C@414999|Opitutae	414999|Opitutae	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	-	-	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
TH3_k127_199978_5	497964.CfE428DRAFT_4585	1.996e-112	365.0	COG0175@1|root,COG0175@2|Bacteria,46SNE@74201|Verrucomicrobia	74201|Verrucomicrobia	EH	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
TH3_k127_199978_2	452637.Oter_2430	6.826e-169	533.0	COG0175@1|root,COG0175@2|Bacteria,46TUQ@74201|Verrucomicrobia,3K7NR@414999|Opitutae	74201|Verrucomicrobia	H	PFAM phosphoadenosine phosphosulfate reductase	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
TH3_k127_199978_1	497964.CfE428DRAFT_4587	3.047e-232	725.0	COG2895@1|root,COG2895@2|Bacteria,46SN4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
TH3_k127_199978_6	272134.KB731325_gene653	8.086e-69	236.0	COG1943@1|root,COG1943@2|Bacteria,1G9TK@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
TH3_k127_2050498_3	497964.CfE428DRAFT_2498	6.781e-31	126.0	COG0707@1|root,COG0707@2|Bacteria,46SRU@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Monogalactosyldiacylglycerol (MGDG) synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
TH3_k127_2050498_1	314230.DSM3645_06659	2.411e-73	265.0	COG4850@1|root,COG4850@2|Bacteria,2IZDS@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
TH3_k127_2050498_2	56780.SYN_01800	1.271e-31	134.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2MQGD@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TH3_k127_2050498_4	28444.JODQ01000006_gene10	1.654e-07	66.0	COG2931@1|root,COG3204@1|root,COG2931@2|Bacteria,COG3204@2|Bacteria,2I94U@201174|Actinobacteria	201174|Actinobacteria	K	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD,Phytase-like
TH3_k127_2050498_0	1396141.BATP01000040_gene2165	1.425e-143	501.0	COG2312@1|root,COG4870@1|root,COG5337@1|root,COG2312@2|Bacteria,COG4870@2|Bacteria,COG5337@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	cotH	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH,Erythro_esteras,LTD,Peptidase_C1
TH3_k127_2066986_6	671143.DAMO_0981	1.803e-226	712.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,2NQV4@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
TH3_k127_2066986_60	236097.ADG881_2747	1.371e-34	138.0	COG0346@1|root,COG0346@2|Bacteria,1N8P0@1224|Proteobacteria,1SGYP@1236|Gammaproteobacteria,1XPDJ@135619|Oceanospirillales	135619|Oceanospirillales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TH3_k127_2066986_50	269799.Gmet_2492	9.44e-60	215.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2WNPH@28221|Deltaproteobacteria,43U0C@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
TH3_k127_2066986_0	497964.CfE428DRAFT_2824	0.0	2724.0	2DBSP@1|root,2ZAT9@2|Bacteria,46TYZ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2066986_9	497964.CfE428DRAFT_2825	2.342e-196	657.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,46TEF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Von Willebrand factor	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,VWA_3,vWF_A
TH3_k127_2066986_47	497964.CfE428DRAFT_2826	1.244e-61	219.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_2066986_78	177437.HRM2_37840	1.142e-05	55.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42NWT@68525|delta/epsilon subdivisions,2X5DA@28221|Deltaproteobacteria,2MMYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TH3_k127_2066986_25	234267.Acid_5336	2.253e-120	424.0	COG0642@1|root,COG0784@1|root,COG3292@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,3Y3IC@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
TH3_k127_2066986_74	313628.LNTAR_17808	2.324e-10	70.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_2066986_16	56110.Oscil6304_5908	2.63e-149	480.0	COG0309@1|root,COG0309@2|Bacteria,1G1Z7@1117|Cyanobacteria,1H82T@1150|Oscillatoriales	1117|Cyanobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
TH3_k127_2066986_11	204669.Acid345_1705	2.121e-178	568.0	COG0409@1|root,COG0409@2|Bacteria,3Y405@57723|Acidobacteria,2JIK0@204432|Acidobacteriia	204432|Acidobacteriia	O	Hydrogenase formation hypA family	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
TH3_k127_2066986_63	518766.Rmar_2594	1.395e-27	113.0	COG0298@1|root,COG0298@2|Bacteria,4NX9T@976|Bacteroidetes	976|Bacteroidetes	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
TH3_k127_2066986_2	272134.KB731324_gene5867	2.386e-259	823.0	COG0068@1|root,COG0068@2|Bacteria,1G063@1117|Cyanobacteria,1H71F@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
TH3_k127_2066986_61	1173027.Mic7113_3070	3.992e-31	126.0	COG0375@1|root,COG0375@2|Bacteria,1G89Y@1117|Cyanobacteria,1HCJX@1150|Oscillatoriales	1117|Cyanobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
TH3_k127_2066986_33	1173028.ANKO01000017_gene232	2.576e-90	312.0	COG0378@1|root,COG0378@2|Bacteria,1G2X6@1117|Cyanobacteria,1H8P3@1150|Oscillatoriales	1117|Cyanobacteria	KO	Ni2 binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
TH3_k127_2066986_44	1384056.N787_01780	1.354e-68	239.0	2AP2K@1|root,31E40@2|Bacteria,1N3BH@1224|Proteobacteria,1STBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2066986_45	1123508.JH636443_gene4582	5.391e-65	236.0	COG1721@1|root,COG1721@2|Bacteria,2IY59@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TH3_k127_2066986_37	452637.Oter_0382	1.014e-85	289.0	COG2041@1|root,COG2041@2|Bacteria,46TCM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
TH3_k127_2066986_31	756499.Desde_3002	7.156e-102	344.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25ZZ7@186807|Peptococcaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
TH3_k127_2066986_22	1396141.BATP01000060_gene4642	2.34e-124	408.0	COG0592@1|root,COG0592@2|Bacteria,46SPK@74201|Verrucomicrobia,2ITMH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
TH3_k127_2066986_51	497964.CfE428DRAFT_6475	4.219e-58	211.0	COG2133@1|root,COG2133@2|Bacteria,46UM9@74201|Verrucomicrobia	2|Bacteria	G	Domain of Unknown Function (DUF1080)	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,DUF1080,F5_F8_type_C
TH3_k127_2066986_8	497964.CfE428DRAFT_4840	2.273e-196	624.0	COG0606@1|root,COG0606@2|Bacteria,46SAK@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
TH3_k127_2066986_29	204536.SULAZ_0984	8.444e-106	357.0	COG1060@1|root,COG1060@2|Bacteria,2G3M7@200783|Aquificae	200783|Aquificae	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Radical_SAM
TH3_k127_2066986_7	1396418.BATQ01000012_gene4420	1.716e-199	627.0	COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia,2ITRB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TH3_k127_2066986_81	794903.OPIT5_23755	5.622e-05	48.0	COG0179@1|root,COG0179@2|Bacteria,46SDD@74201|Verrucomicrobia,3K7IJ@414999|Opitutae	414999|Opitutae	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
TH3_k127_2066986_72	1303518.CCALI_02308	3.081e-12	77.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_2066986_71	1123508.JH636446_gene6223	4.43e-13	79.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_2066986_68	272123.Anacy_5162	4.846e-17	96.0	COG0739@1|root,COG2931@1|root,COG0739@2|Bacteria,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
TH3_k127_2066986_70	1303518.CCALI_00162	2.956e-13	81.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10,T2SSG
TH3_k127_2066986_23	794903.OPIT5_23755	7.069e-123	400.0	COG0179@1|root,COG0179@2|Bacteria,46SDD@74201|Verrucomicrobia,3K7IJ@414999|Opitutae	414999|Opitutae	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
TH3_k127_2066986_28	497964.CfE428DRAFT_5447	2.848e-112	374.0	COG0758@1|root,COG0758@2|Bacteria,46SGR@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM DNA protecting protein DprA	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
TH3_k127_2066986_5	497964.CfE428DRAFT_6713	9.54e-235	737.0	COG3961@1|root,COG3961@2|Bacteria,46UYW@74201|Verrucomicrobia	74201|Verrucomicrobia	GH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TH3_k127_2066986_55	324057.Pjdr2_0886	5.183e-50	194.0	COG1470@1|root,COG3210@1|root,COG4447@1|root,COG4932@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4447@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,CHB_HEX_C_1,Cadherin-like,Flg_new,SLH,fn3
TH3_k127_2066986_27	794903.OPIT5_28885	6.501e-114	382.0	COG0489@1|root,COG0489@2|Bacteria,46SAV@74201|Verrucomicrobia,3K75Q@414999|Opitutae	414999|Opitutae	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
TH3_k127_2066986_65	1265503.KB905160_gene2883	3.76e-27	122.0	2BC7U@1|root,325SP@2|Bacteria,1QMVW@1224|Proteobacteria,1TK6J@1236|Gammaproteobacteria,2Q7XB@267889|Colwelliaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2066986_24	344747.PM8797T_11556	9.605e-121	402.0	COG0673@1|root,COG0673@2|Bacteria,2IXA3@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_2066986_46	1123242.JH636434_gene5340	5.409e-62	232.0	COG1413@1|root,COG1413@2|Bacteria,2IZE1@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
TH3_k127_2066986_77	742766.HMPREF9455_02417	1.929e-06	56.0	COG1413@1|root,COG1413@2|Bacteria,4NEZ7@976|Bacteroidetes,2FPRF@200643|Bacteroidia,22X0G@171551|Porphyromonadaceae	976|Bacteroidetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,HEAT_2
TH3_k127_2066986_62	1047013.AQSP01000114_gene693	6.43e-28	119.0	2E74N@1|root,331P2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2066986_26	497964.CfE428DRAFT_3356	3.103e-118	399.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,46TMH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Nucleoside recognition	-	-	-	-	-	-	-	-	-	-	-	-	Gate
TH3_k127_2066986_18	497964.CfE428DRAFT_2607	3.1e-133	431.0	COG0540@1|root,COG0540@2|Bacteria,46S9E@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
TH3_k127_2066986_53	1521187.JPIM01000042_gene1869	5.637e-56	202.0	COG2065@1|root,COG2065@2|Bacteria,2G6WS@200795|Chloroflexi,375J4@32061|Chloroflexia	32061|Chloroflexia	F	Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
TH3_k127_2066986_67	497964.CfE428DRAFT_2605	1.839e-21	96.0	2E99J@1|root,333HQ@2|Bacteria,46T77@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032
TH3_k127_2066986_30	401526.TcarDRAFT_0104	5.397e-102	357.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H20M@909932|Negativicutes	909932|Negativicutes	V	lipid A export permease ATP-binding protein MsbA	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
TH3_k127_2066986_36	690850.Desaf_0024	2.543e-86	293.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,42M23@68525|delta/epsilon subdivisions,2WNU9@28221|Deltaproteobacteria,2MHBU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TH3_k127_2066986_48	690850.Desaf_0021	1.634e-61	227.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria,2MG43@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TH3_k127_2066986_59	1485545.JQLW01000005_gene1063	6.431e-43	166.0	COG2227@1|root,COG2227@2|Bacteria,1QY24@1224|Proteobacteria	1224|Proteobacteria	H	Pfam Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
TH3_k127_2066986_38	926549.KI421517_gene437	5.156e-84	285.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,SAM_MT
TH3_k127_2066986_73	756067.MicvaDRAFT_4986	1.55e-10	73.0	COG2755@1|root,COG2755@2|Bacteria,1G060@1117|Cyanobacteria,1H9JP@1150|Oscillatoriales	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
TH3_k127_2066986_52	402881.Plav_1911	5.442e-57	215.0	COG0742@1|root,COG0742@2|Bacteria	2|Bacteria	L	rRNA (guanine-N2-)-methyltransferase activity	-	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Cons_hypoth95,SAM_MT
TH3_k127_2066986_79	1167006.UWK_02438	1.154e-05	57.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	2.7.1.119	ko:K17880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH,EcKinase,HMG-CoA_red
TH3_k127_2066986_43	880072.Desac_2043	2.226e-71	256.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,42P4A@68525|delta/epsilon subdivisions,2WPG9@28221|Deltaproteobacteria,2MRJ3@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PFAM Glycosyl transferase, group 1	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TH3_k127_2066986_39	335543.Sfum_3152	1.661e-80	275.0	COG0500@1|root,COG2226@2|Bacteria,1NGTM@1224|Proteobacteria	1224|Proteobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TH3_k127_2066986_42	497964.CfE428DRAFT_3065	1.132e-71	250.0	2F2JH@1|root,33VGF@2|Bacteria	2|Bacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
TH3_k127_2066986_66	1123508.JH636439_gene1468	3.981e-23	114.0	COG0515@1|root,COG3642@1|root,COG0515@2|Bacteria,COG3642@2|Bacteria,2IZTN@203682|Planctomycetes	203682|Planctomycetes	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
TH3_k127_2066986_40	237368.SCABRO_03057	2.255e-77	275.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
TH3_k127_2066986_12	204669.Acid345_0011	4.602e-164	530.0	COG5316@1|root,COG5316@2|Bacteria,3Y4FP@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
TH3_k127_2066986_20	251221.35211608	2.289e-130	435.0	COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
TH3_k127_2066986_41	497964.CfE428DRAFT_1462	1.813e-72	256.0	COG0084@1|root,COG0084@2|Bacteria,46SRB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM TatD-related deoxyribonuclease	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
TH3_k127_2066986_34	497964.CfE428DRAFT_1464	4.223e-89	301.0	COG1179@1|root,COG1179@2|Bacteria,46THP@74201|Verrucomicrobia	74201|Verrucomicrobia	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
TH3_k127_2066986_15	1236959.BAMT01000001_gene1712	4.644e-154	512.0	COG0515@1|root,COG0515@2|Bacteria,1R6F6@1224|Proteobacteria,2W1UW@28216|Betaproteobacteria,2KKN2@206350|Nitrosomonadales	206350|Nitrosomonadales	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
TH3_k127_2066986_75	243230.DR_0026	6.483e-09	67.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
TH3_k127_2066986_19	886293.Sinac_2458	2.521e-132	432.0	COG0399@1|root,COG0399@2|Bacteria,2IXZR@203682|Planctomycetes	203682|Planctomycetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TH3_k127_2066986_64	794903.OPIT5_25305	2.129e-27	121.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_7
TH3_k127_2066986_13	497964.CfE428DRAFT_4532	2.32e-159	516.0	COG0737@1|root,COG0737@2|Bacteria,46TFI@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
TH3_k127_2066986_35	497964.CfE428DRAFT_4533	6.755e-88	297.0	COG1657@1|root,COG1657@2|Bacteria,46TYK@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
TH3_k127_2066986_1	497964.CfE428DRAFT_4534	1.717e-261	837.0	COG1196@1|root,COG1196@2|Bacteria,46TX7@74201|Verrucomicrobia	74201|Verrucomicrobia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2066986_3	497964.CfE428DRAFT_2093	7.849e-252	796.0	COG2304@1|root,COG2304@2|Bacteria,46UTA@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2066986_4	497964.CfE428DRAFT_4542	3.938e-247	782.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB,DUF4091,Glyco_hydro_71,HYR,Hint_2,Peptidase_C11
TH3_k127_2066986_21	497964.CfE428DRAFT_4543	9.792e-129	420.0	COG1721@1|root,COG1721@2|Bacteria,46TKV@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TH3_k127_2066986_14	497964.CfE428DRAFT_4544	1.126e-155	501.0	COG0714@1|root,COG0714@2|Bacteria,46TCY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM ATPase associated with various cellular activities AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TH3_k127_2066986_17	720554.Clocl_3102	4.036e-139	449.0	COG0119@1|root,COG0119@2|Bacteria,1TS0A@1239|Firmicutes,247MU@186801|Clostridia,3WHBT@541000|Ruminococcaceae	186801|Clostridia	E	HMGL-like	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
TH3_k127_2066986_56	794903.OPIT5_16315	1.28e-47	175.0	COG1327@1|root,COG1327@2|Bacteria,46VCN@74201|Verrucomicrobia,3K7XU@414999|Opitutae	414999|Opitutae	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
TH3_k127_2066986_57	317619.ANKN01000004_gene815	2.265e-45	166.0	COG0537@1|root,COG0537@2|Bacteria,1G6R2@1117|Cyanobacteria,1MMGN@1212|Prochloraceae	1117|Cyanobacteria	FG	Alternative locus ID	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
TH3_k127_2066986_32	1123508.JH636442_gene4185	1.198e-101	347.0	COG1167@1|root,COG1167@2|Bacteria,2IY9J@203682|Planctomycetes	203682|Planctomycetes	EK	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
TH3_k127_2066986_49	82654.Pse7367_2890	9.605e-61	221.0	COG1073@1|root,COG1073@2|Bacteria,1G1YP@1117|Cyanobacteria,1H80J@1150|Oscillatoriales	1117|Cyanobacteria	S	Alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
TH3_k127_2066986_54	497964.CfE428DRAFT_5026	1.42e-53	199.0	2DXTF@1|root,346G5@2|Bacteria,46W16@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2066986_69	756272.Plabr_3146	1.878e-13	80.0	COG5492@1|root,COG5492@2|Bacteria,2IYV9@203682|Planctomycetes	203682|Planctomycetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
TH3_k127_2066986_10	497964.CfE428DRAFT_4943	3.503e-190	623.0	COG0577@1|root,COG0577@2|Bacteria,46U6N@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
TH3_k127_2074992_1	338966.Ppro_2630	1.455e-53	195.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria,43U15@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
TH3_k127_2074992_0	264732.Moth_2127	4.571e-105	349.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,42FGV@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
TH3_k127_2074992_3	1379698.RBG1_1C00001G1401	3.776e-17	91.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
TH3_k127_2074992_2	396588.Tgr7_1840	6.18e-20	89.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1WVYY@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM isocitrate dehydrogenase, NADP-dependent	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,Iso_dh
TH3_k127_2080240_0	497964.CfE428DRAFT_4266	8.211e-284	887.0	COG4409@1|root,COG4409@2|Bacteria,46U32@74201|Verrucomicrobia	74201|Verrucomicrobia	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TH3_k127_2080240_1	1396418.BATQ01000085_gene1081	3.92e-90	312.0	COG3664@1|root,COG3664@2|Bacteria,46UDS@74201|Verrucomicrobia,2IWDZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolases family 39	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
TH3_k127_2080240_2	1122931.AUAE01000007_gene1340	7.075e-40	154.0	COG5434@1|root,COG5434@2|Bacteria,4PMGR@976|Bacteroidetes	976|Bacteroidetes	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TH3_k127_2103737_1	497964.CfE428DRAFT_0415	3.809e-175	560.0	COG2256@1|root,COG2256@2|Bacteria,46S7H@74201|Verrucomicrobia	74201|Verrucomicrobia	L	AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
TH3_k127_2103737_20	1123252.ATZF01000020_gene2901	3.607e-25	112.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,27C4B@186824|Thermoactinomycetaceae	91061|Bacilli	H	5-formyltetrahydrofolate cyclo-ligase family	fthC	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
TH3_k127_2103737_3	1382304.JNIL01000001_gene534	8.523e-139	458.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,277VR@186823|Alicyclobacillaceae	91061|Bacilli	S	Endoribonuclease that initiates mRNA decay	rny	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
TH3_k127_2103737_25	478741.JAFS01000002_gene111	1.018e-06	59.0	COG1196@1|root,COG1196@2|Bacteria,46Z83@74201|Verrucomicrobia,37GKF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2103737_19	391587.KAOT1_16038	3.497e-25	115.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,1HYKU@117743|Flavobacteriia	976|Bacteroidetes	T	tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
TH3_k127_2103737_14	309807.SRU_2566	6.062e-35	153.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1FJBA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
TH3_k127_2103737_16	717605.Theco_1040	1.484e-28	124.0	COG0128@1|root,COG0128@2|Bacteria,1VK19@1239|Firmicutes,4HQZ9@91061|Bacilli,26WZM@186822|Paenibacillaceae	91061|Bacilli	E	3-phosphoshikimate 1-carboxyvinyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2103737_6	497964.CfE428DRAFT_1897	2.508e-88	304.0	COG0679@1|root,COG0679@2|Bacteria,46SPM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
TH3_k127_2103737_2	497964.CfE428DRAFT_0339	7.831e-158	512.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,46S9P@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Belongs to the precorrin methyltransferase family	cysG	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
TH3_k127_2103737_15	247490.KSU1_C0558	3.694e-31	126.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
TH3_k127_2103737_18	247490.KSU1_C0559	9.493e-26	107.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2103737_7	1303518.CCALI_00360	1.563e-76	271.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
TH3_k127_2103737_21	59374.Fisuc_2149	2.247e-24	113.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TH3_k127_2103737_12	497964.CfE428DRAFT_2959	1.585e-46	178.0	2ED0A@1|root,336X9@2|Bacteria,46TCE@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2103737_13	554065.XP_005846247.1	6.902e-36	143.0	COG1011@1|root,KOG3085@2759|Eukaryota,382V1@33090|Viridiplantae	33090|Viridiplantae	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2103737_8	570268.ANBB01000059_gene4179	5.439e-64	224.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4EG4M@85012|Streptosporangiales	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
TH3_k127_2103737_22	1121472.AQWN01000007_gene1087	4.443e-24	107.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,262CP@186807|Peptococcaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
TH3_k127_2103737_4	1396418.BATQ01000129_gene4821	5.864e-132	442.0	COG2812@1|root,COG2812@2|Bacteria,46SGC@74201|Verrucomicrobia,2ITGI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
TH3_k127_2103737_5	435591.BDI_2467	1.013e-90	315.0	COG5434@1|root,COG5434@2|Bacteria,4NFSC@976|Bacteroidetes,2FNQN@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
TH3_k127_2103737_0	794903.OPIT5_28170	3.096e-210	668.0	COG0519@1|root,COG0519@2|Bacteria,46SIW@74201|Verrucomicrobia,3K77S@414999|Opitutae	414999|Opitutae	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
TH3_k127_2103737_9	1122919.KB905591_gene4021	1.855e-61	230.0	COG1520@1|root,COG1520@2|Bacteria,1UIHU@1239|Firmicutes,4ISIB@91061|Bacilli,2773B@186822|Paenibacillaceae	91061|Bacilli	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2103737_23	1123276.KB893252_gene3670	3.55e-15	89.0	COG2755@1|root,COG2931@1|root,COG3210@1|root,COG3391@1|root,COG4625@1|root,COG4886@1|root,COG5184@1|root,COG5492@1|root,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4625@2|Bacteria,COG4886@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4PPHP@976|Bacteroidetes,47XC8@768503|Cytophagia	976|Bacteroidetes	E	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
TH3_k127_2103737_10	1192034.CAP_0893	9.47e-59	231.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
TH3_k127_2103737_17	203124.Tery_0657	4.638e-28	132.0	COG3391@1|root,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria,1H803@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
TH3_k127_2103737_11	1173028.ANKO01000090_gene3474	8.807e-49	189.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1G4N6@1117|Cyanobacteria	1117|Cyanobacteria	KLT	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
TH3_k127_2192702_3	228405.HNE_2556	1.802e-07	53.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,43X59@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	Recombinase	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TH3_k127_2192702_2	234267.Acid_4752	6.171e-92	311.0	COG4974@1|root,COG4974@2|Bacteria,3Y68K@57723|Acidobacteria	57723|Acidobacteria	L	phage integrase domain protein SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
TH3_k127_2192702_0	234267.Acid_3308	7.704e-161	515.0	COG0517@1|root,COG0517@2|Bacteria,3Y6WE@57723|Acidobacteria	57723|Acidobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
TH3_k127_2192702_1	330214.NIDE0014	3.668e-139	451.0	COG0655@1|root,COG2146@1|root,COG0655@2|Bacteria,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	1.2.3.3,1.6.5.2,1.7.1.15	ko:K00158,ko:K00363,ko:K03809,ko:K05710	ko00130,ko00360,ko00620,ko00910,ko01100,ko01110,ko01120,ko01220,map00130,map00360,map00620,map00910,map01100,map01110,map01120,map01220	M00530,M00545	R00207,R00787,R02964,R03643,R03816,R06782,R06783	RC00098,RC00176,RC00819,RC02745	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_red,Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TH3_k127_2202561_3	931277.C448_03736	6.094e-12	75.0	arCOG02980@1|root,arCOG02980@2157|Archaea,2XTKT@28890|Euryarchaeota,23SJA@183963|Halobacteria	183963|Halobacteria	S	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2202561_5	1198114.AciX9_1011	5.258e-07	52.0	COG3440@1|root,COG3440@2|Bacteria	2|Bacteria	V	regulation of methylation-dependent chromatin silencing	hphI	-	-	ko:K07454	-	-	-	-	ko00000	-	-	-	HNH_2
TH3_k127_2202561_7	246969.TAM4_601	0.0003157	46.0	COG2002@1|root,arCOG00812@2157|Archaea,2Y6IB@28890|Euryarchaeota,244N0@183968|Thermococci	183968|Thermococci	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
TH3_k127_2202561_1	264732.Moth_0652	1.033e-20	96.0	COG1569@1|root,COG1569@2|Bacteria,1V6UC@1239|Firmicutes,24KEA@186801|Clostridia,42HGV@68295|Thermoanaerobacterales	186801|Clostridia	S	PIN domain	-	-	-	ko:K07063	-	-	-	-	ko00000	-	-	-	PIN_3
TH3_k127_2202561_4	1123368.AUIS01000001_gene1877	3.788e-10	63.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RRVF@1236|Gammaproteobacteria,2NCS0@225057|Acidithiobacillales	225057|Acidithiobacillales	V	N-6 DNA Methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_Mtase
TH3_k127_2202561_0	1173027.Mic7113_4793	8.946e-126	432.0	COG1680@1|root,COG1680@2|Bacteria,1G4D0@1117|Cyanobacteria,1HFEP@1150|Oscillatoriales	1117|Cyanobacteria	V	PFAM beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TH3_k127_2202561_2	629265.PMA4326_14224	3.084e-13	75.0	2EKGR@1|root,33E6S@2|Bacteria,1NQ4Y@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2219175_31	404589.Anae109_0137	1.854e-74	269.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WNXT@28221|Deltaproteobacteria,2YV4W@29|Myxococcales	28221|Deltaproteobacteria	EGP	of the major facilitator superfamily	agmP	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,Sugar_tr
TH3_k127_2219175_36	909663.KI867150_gene1086	2.353e-64	231.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42N8J@68525|delta/epsilon subdivisions,2WK63@28221|Deltaproteobacteria,2MRGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_2219175_67	1396141.BATP01000023_gene664	1.02e-10	73.0	COG2931@1|root,COG3266@1|root,COG4733@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB,DUF1499,Flg_new
TH3_k127_2219175_37	1042375.AFPL01000055_gene2315	2.289e-61	222.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,1SYQY@1236|Gammaproteobacteria,467K2@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	nreC	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
TH3_k127_2219175_9	1131269.AQVV01000050_gene421	2.432e-181	580.0	COG0305@1|root,COG0305@2|Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
TH3_k127_2219175_11	1156937.MFUM_230019	1.592e-158	530.0	COG4775@1|root,COG4775@2|Bacteria,46S5F@74201|Verrucomicrobia,37GCF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
TH3_k127_2219175_18	247490.KSU1_C0714	2.813e-128	454.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
TH3_k127_2219175_64	1166018.FAES_3046	8.218e-15	90.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47M5A@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
TH3_k127_2219175_65	497964.CfE428DRAFT_4704	1.635e-14	82.0	COG2825@1|root,COG2825@2|Bacteria,46T22@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM outer membrane chaperone Skp (OmpH)	hlpA	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TH3_k127_2219175_8	497964.CfE428DRAFT_6478	3.524e-187	593.0	COG1453@1|root,COG1453@2|Bacteria,46S6J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
TH3_k127_2219175_52	497964.CfE428DRAFT_6673	4.667e-27	113.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
TH3_k127_2219175_16	1288963.ADIS_2835	3.35e-131	435.0	COG3356@1|root,COG3356@2|Bacteria,4NH6U@976|Bacteroidetes,47NFZ@768503|Cytophagia	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
TH3_k127_2219175_13	478741.JAFS01000001_gene1976	5.104e-147	475.0	COG0798@1|root,COG0798@2|Bacteria,46UD3@74201|Verrucomicrobia,37FUU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
TH3_k127_2219175_49	794903.OPIT5_06500	1.313e-31	141.0	COG0640@1|root,COG0640@2|Bacteria,46WF9@74201|Verrucomicrobia,3K8BI@414999|Opitutae	414999|Opitutae	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
TH3_k127_2219175_22	1163617.SCD_n02152	7.671e-105	346.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2VQVG@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
TH3_k127_2219175_42	497964.CfE428DRAFT_5842	1.027e-49	181.0	COG1595@1|root,COG1595@2|Bacteria,46W91@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_2219175_34	926550.CLDAP_10330	5.475e-68	238.0	COG0328@1|root,COG0328@2|Bacteria,2G6PS@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
TH3_k127_2219175_48	880072.Desac_0616	1.257e-34	145.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_M78
TH3_k127_2219175_58	1220534.B655_1532	4.486e-21	102.0	COG0655@1|root,arCOG02573@2157|Archaea,2XVMU@28890|Euryarchaeota,23PMW@183925|Methanobacteria	183925|Methanobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
TH3_k127_2219175_23	909663.KI867150_gene1425	4.238e-97	325.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria,2MS43@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
TH3_k127_2219175_50	1121918.ARWE01000001_gene2103	2.061e-31	139.0	COG0526@1|root,COG0526@2|Bacteria,1N0R9@1224|Proteobacteria,42UD9@68525|delta/epsilon subdivisions,2WQ0H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	PFAM Thioredoxin	trx-2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
TH3_k127_2219175_59	1499967.BAYZ01000050_gene2842	6.486e-20	91.0	COG0526@1|root,COG0526@2|Bacteria,2NQ71@2323|unclassified Bacteria	2|Bacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Thioredoxin_3
TH3_k127_2219175_10	595460.RRSWK_03127	1.26e-167	537.0	COG0701@1|root,COG0701@2|Bacteria,2J0GE@203682|Planctomycetes	203682|Planctomycetes	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
TH3_k127_2219175_55	706587.Desti_5389	8.152e-22	99.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,42V3T@68525|delta/epsilon subdivisions,2WS3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	regulatory protein, arsR	-	-	-	ko:K03892,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
TH3_k127_2219175_25	452637.Oter_2551	2.383e-96	326.0	COG5002@1|root,COG5002@2|Bacteria,46SSA@74201|Verrucomicrobia,3K7XI@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TH3_k127_2219175_28	452637.Oter_2550	2.84e-84	291.0	COG0745@1|root,COG0745@2|Bacteria,46SS3@74201|Verrucomicrobia,3K7XM@414999|Opitutae	414999|Opitutae	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TH3_k127_2219175_33	452637.Oter_2549	7.415e-70	243.0	COG0704@1|root,COG0704@2|Bacteria,46SUX@74201|Verrucomicrobia,3K824@414999|Opitutae	414999|Opitutae	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
TH3_k127_2219175_20	1286106.MPL1_06769	8.28e-115	376.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,46073@72273|Thiotrichales	72273|Thiotrichales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
TH3_k127_2219175_24	1242864.D187_004631	7.417e-97	338.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2YVAR@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
TH3_k127_2219175_30	290397.Adeh_4005	1.593e-82	289.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2YV6J@29|Myxococcales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
TH3_k127_2219175_29	290397.Adeh_4006	1.1e-82	284.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,2YVQ5@29|Myxococcales	28221|Deltaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
TH3_k127_2219175_26	247634.GPB2148_1563	5.451e-88	304.0	COG3746@1|root,COG3746@2|Bacteria,1NT6B@1224|Proteobacteria,1SM5C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
TH3_k127_2219175_27	344747.PM8797T_29862	2.264e-84	291.0	COG1082@1|root,COG1082@2|Bacteria,2J0ZG@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_2219175_17	661478.OP10G_0861	6.753e-131	429.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
TH3_k127_2219175_0	1123242.JH636435_gene1197	5.293e-275	858.0	COG3119@1|root,COG3119@2|Bacteria,2IXWN@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TH3_k127_2219175_5	240016.ABIZ01000001_gene5457	5.262e-214	676.0	COG3119@1|root,COG3119@2|Bacteria,46U45@74201|Verrucomicrobia,2IV5A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TH3_k127_2219175_4	521674.Plim_1566	2.28e-223	710.0	COG1413@1|root,COG3119@1|root,COG1413@2|Bacteria,COG3119@2|Bacteria,2IYFZ@203682|Planctomycetes	203682|Planctomycetes	CP	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
TH3_k127_2219175_2	1123242.JH636435_gene1179	1.225e-260	811.0	COG3119@1|root,COG3119@2|Bacteria,2IXHT@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TH3_k127_2219175_1	595460.RRSWK_04657	2.377e-272	845.0	COG3119@1|root,COG3119@2|Bacteria,2IWVY@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
TH3_k127_2219175_14	62928.azo2300	9.391e-139	452.0	COG1055@1|root,COG1055@2|Bacteria,1N68M@1224|Proteobacteria,2VH3A@28216|Betaproteobacteria,2KVZG@206389|Rhodocyclales	206389|Rhodocyclales	P	Putative Na+/H+ antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_3
TH3_k127_2219175_3	497964.CfE428DRAFT_4597	3.24e-231	726.0	COG4108@1|root,COG4108@2|Bacteria,46SF9@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
TH3_k127_2219175_12	483219.LILAB_30160	1.494e-154	498.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,42QCN@68525|delta/epsilon subdivisions,2WIYT@28221|Deltaproteobacteria,2YV4K@29|Myxococcales	28221|Deltaproteobacteria	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
TH3_k127_2219175_68	164757.Mjls_1689	7.641e-09	63.0	COG3583@1|root,COG3666@1|root,COG3583@2|Bacteria,COG3666@2|Bacteria,2H4RU@201174|Actinobacteria,235V0@1762|Mycobacteriaceae	201174|Actinobacteria	L	Resuscitation-promoting factor rpfB	rpfB	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
TH3_k127_2219175_60	794903.OPIT5_13650	7.066e-20	103.0	2AXAG@1|root,30YNX@2|Bacteria,46YVC@74201|Verrucomicrobia,3K96I@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2219175_39	485918.Cpin_0414	1.841e-60	212.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1ISI6@117747|Sphingobacteriia	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
TH3_k127_2219175_71	1379698.RBG1_1C00001G0366	1.748e-06	60.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	Reg_prop,Y_Y_Y
TH3_k127_2219175_32	583355.Caka_1736	1.747e-71	278.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
TH3_k127_2219175_15	382464.ABSI01000013_gene1549	7.43e-137	494.0	COG2312@1|root,COG3211@1|root,COG2312@2|Bacteria,COG3211@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
TH3_k127_2219175_57	1396141.BATP01000030_gene3719	1.627e-21	113.0	COG3119@1|root,COG3211@1|root,COG3656@1|root,COG5337@1|root,COG3119@2|Bacteria,COG3211@2|Bacteria,COG3656@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	phoX	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	CotH,DUF839
TH3_k127_2219175_43	1396141.BATP01000022_gene383	1.769e-49	195.0	COG1595@1|root,COG1595@2|Bacteria,46TQ4@74201|Verrucomicrobia,2IVYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4
TH3_k127_2219175_54	382464.ABSI01000006_gene874	6.67e-25	112.0	COG1595@1|root,COG1595@2|Bacteria,46XM2@74201|Verrucomicrobia,2IW65@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_2219175_6	1156937.MFUM_90002	4.897e-194	617.0	COG0034@1|root,COG0034@2|Bacteria,46SSU@74201|Verrucomicrobia,37G3Z@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
TH3_k127_2219175_21	945713.IALB_2895	3.47e-107	367.0	COG0719@1|root,COG0719@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	sufD	GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144	UPF0051
TH3_k127_2219175_47	265729.GS18_0220400	1.685e-37	150.0	2DSM2@1|root,33GKP@2|Bacteria,1VKZ8@1239|Firmicutes,4HSD9@91061|Bacilli,1ZJS2@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4259
TH3_k127_2219175_46	1089547.KB913013_gene1006	5.547e-41	155.0	COG0251@1|root,COG0251@2|Bacteria,4NR3V@976|Bacteroidetes,47QRJ@768503|Cytophagia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
TH3_k127_2219175_35	765420.OSCT_3130	1.128e-65	258.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
TH3_k127_2219175_72	102129.Lepto7375DRAFT_0067	9.822e-05	47.0	298NA@1|root,2ZVSW@2|Bacteria	2|Bacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	-
TH3_k127_2219175_61	497964.CfE428DRAFT_0488	1.353e-19	91.0	COG0089@1|root,COG0089@2|Bacteria,46WBX@74201|Verrucomicrobia	74201|Verrucomicrobia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
TH3_k127_2219175_44	1089553.Tph_c25840	6.109e-49	182.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,42ERX@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
TH3_k127_2219175_38	1121381.JNIV01000084_gene822	4e-61	218.0	COG0087@1|root,COG0087@2|Bacteria,1WI2F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
TH3_k127_2219175_45	497964.CfE428DRAFT_0485	1.222e-46	169.0	COG0051@1|root,COG0051@2|Bacteria,46SVV@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
TH3_k127_2219175_63	382464.ABSI01000005_gene1327	8.557e-16	78.0	2DSQH@1|root,33H1Z@2|Bacteria,46TBQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2219175_40	1122130.AUHN01000008_gene1512	1.493e-59	214.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TH3_k127_2219175_69	1301100.HG529244_gene2342	3.268e-08	65.0	COG3103@1|root,COG3807@1|root,COG4193@1|root,COG3103@2|Bacteria,COG3807@2|Bacteria,COG4193@2|Bacteria,COG4991@2|Bacteria,1V0NC@1239|Firmicutes,25BAR@186801|Clostridia,36WMT@31979|Clostridiaceae	186801|Clostridia	GT	Src homology 3 domains	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,SH3_3
TH3_k127_2219175_53	1236689.MMALV_01900	3.923e-26	114.0	COG2759@1|root,arCOG04538@2157|Archaea,2XTE0@28890|Euryarchaeota,3F2M9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
TH3_k127_2219175_66	794903.OPIT5_05255	9.946e-12	74.0	COG0457@1|root,COG1652@1|root,COG0457@2|Bacteria,COG1652@2|Bacteria,46T8E@74201|Verrucomicrobia,3K82V@414999|Opitutae	414999|Opitutae	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
TH3_k127_2219175_74	243233.MCA1174	0.0002558	53.0	COG5338@1|root,COG5338@2|Bacteria,1R56M@1224|Proteobacteria,1S0PC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative beta-barrel porin 2	-	-	-	ko:K20920	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.66.3.1,1.B.66.3.2	-	-	BBP2_2
TH3_k127_2219175_19	497964.CfE428DRAFT_6114	8.039e-125	426.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46SBB@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,Wzz
TH3_k127_2219175_70	794903.OPIT5_22505	1.179e-07	63.0	COG1596@1|root,COG1596@2|Bacteria,46VQY@74201|Verrucomicrobia,3K89I@414999|Opitutae	414999|Opitutae	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
TH3_k127_2219175_73	191610.CATYP_00200	0.0002279	49.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,22M4R@1653|Corynebacteriaceae	201174|Actinobacteria	T	FHA domain	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
TH3_k127_2219175_7	1396141.BATP01000013_gene2687	5.367e-192	611.0	COG0138@1|root,COG0138@2|Bacteria,46S5H@74201|Verrucomicrobia,2ITYZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	AICARFT/IMPCHase bienzyme	-	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
TH3_k127_2336071_1	1123248.KB893318_gene4130	1.064e-169	556.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,1IUSY@117747|Sphingobacteriia	976|Bacteroidetes	G	family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
TH3_k127_2336071_0	234267.Acid_5559	2.309e-175	589.0	COG3250@1|root,COG3408@1|root,COG3250@2|Bacteria,COG3408@2|Bacteria,3Y2YG@57723|Acidobacteria	57723|Acidobacteria	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
TH3_k127_2336071_2	143224.JQMD01000002_gene1793	9.488e-52	188.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,1I0YR@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_106,Glyco_hydro_2_N
TH3_k127_2346536_0	886293.Sinac_6489	1.882e-102	355.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
TH3_k127_2346536_2	497964.CfE428DRAFT_5892	3.487e-05	52.0	COG4968@1|root,COG4968@2|Bacteria,46Z8X@74201|Verrucomicrobia	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	lspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
TH3_k127_2346536_1	497964.CfE428DRAFT_0659	9.785e-12	66.0	COG1301@1|root,COG1301@2|Bacteria,46U9C@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
TH3_k127_2353760_0	886293.Sinac_6122	2.531e-131	429.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
TH3_k127_2353760_1	221288.JH992901_gene3829	3.146e-124	412.0	COG0337@1|root,COG0337@2|Bacteria,1G2JF@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM 3-dehydroquinate synthase	-	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
TH3_k127_2353760_2	1123070.KB899248_gene194	8.651e-94	312.0	COG1524@1|root,COG1524@2|Bacteria,46UZ5@74201|Verrucomicrobia,2ITHB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
TH3_k127_2390140_3	497964.CfE428DRAFT_4864	9.767e-66	237.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2390140_2	1217720.ALOX01000026_gene3512	6.954e-139	456.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JPSC@204441|Rhodospirillales	204441|Rhodospirillales	C	belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TH3_k127_2390140_0	497964.CfE428DRAFT_1010	2.726e-199	632.0	COG0277@1|root,COG0277@2|Bacteria,46S85@74201|Verrucomicrobia	74201|Verrucomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
TH3_k127_2390140_5	234267.Acid_5681	5.473e-22	96.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
TH3_k127_2390140_4	1487953.JMKF01000016_gene2557	1.239e-30	124.0	COG4634@1|root,COG4634@2|Bacteria,1G79I@1117|Cyanobacteria,1HHDK@1150|Oscillatoriales	1117|Cyanobacteria	S	Mut7-C RNAse domain	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
TH3_k127_2390140_1	1396418.BATQ01000127_gene2548	3.699e-164	531.0	COG0247@1|root,COG0247@2|Bacteria,46SAS@74201|Verrucomicrobia,2IUWH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
TH3_k127_240967_1	1123242.JH636435_gene2663	4.88e-26	119.0	COG0526@1|root,COG0526@2|Bacteria,2IXG6@203682|Planctomycetes	203682|Planctomycetes	CO	Thiol-disulfide isomerase and	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TH3_k127_240967_2	338966.Ppro_2636	9.842e-07	59.0	COG3637@1|root,COG3637@2|Bacteria,1NGKR@1224|Proteobacteria,42XMD@68525|delta/epsilon subdivisions,2WSIW@28221|Deltaproteobacteria,43UMH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TH3_k127_240967_0	290315.Clim_0430	6.092e-54	199.0	COG1409@1|root,COG1785@1|root,COG2931@1|root,COG3391@1|root,COG1409@2|Bacteria,COG1785@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,1FDAF@1090|Chlorobi	1090|Chlorobi	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase,SWM_repeat
TH3_k127_2432927_2	383372.Rcas_2444	4.189e-24	120.0	2DQ8H@1|root,335A3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2432927_1	572477.Alvin_0517	2.7e-64	230.0	COG5266@1|root,COG5266@2|Bacteria,1PVKN@1224|Proteobacteria,1RWJZ@1236|Gammaproteobacteria,1WXIW@135613|Chromatiales	135613|Chromatiales	P	PFAM Nickel transport complex, NikM subunit, transmembrane	-	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	DUF4198
TH3_k127_2432927_0	742725.HMPREF9450_01532	6.82e-149	495.0	COG3420@1|root,COG3420@2|Bacteria,4PMG9@976|Bacteroidetes,2FQGR@200643|Bacteroidia	976|Bacteroidetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TH3_k127_2502155_3	382464.ABSI01000009_gene3915	5.833e-31	127.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2502155_2	382464.ABSI01000009_gene3916	5.134e-70	254.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
TH3_k127_2502155_0	382464.ABSI01000009_gene3917	8.537e-132	429.0	COG1131@1|root,COG1131@2|Bacteria,46SHV@74201|Verrucomicrobia,2ITWN@203494|Verrucomicrobiae	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_2502155_1	1303518.CCALI_02490	5.762e-83	285.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_2532661_15	1142394.PSMK_06110	3.495e-12	76.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_2532661_7	880070.Cycma_0098	4.063e-65	240.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	-	-	3.1.3.15	ko:K02347,ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	PHP
TH3_k127_2532661_4	1121011.AUCB01000005_gene2345	8.776e-89	310.0	COG3356@1|root,COG3356@2|Bacteria,4NGDG@976|Bacteroidetes,1I821@117743|Flavobacteriia,23FKJ@178469|Arenibacter	976|Bacteroidetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
TH3_k127_2532661_8	1459636.NTE_02269	4.69e-50	184.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	ssuE1	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
TH3_k127_2532661_6	497964.CfE428DRAFT_4164	1.474e-66	237.0	COG0483@1|root,COG0483@2|Bacteria,46T0Z@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
TH3_k127_2532661_11	1535422.ND16A_0876	4.616e-31	136.0	COG0652@1|root,COG0652@2|Bacteria,1RCXX@1224|Proteobacteria,1S3ZN@1236|Gammaproteobacteria,2Q751@267889|Colwelliaceae	1236|Gammaproteobacteria	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
TH3_k127_2532661_9	1121422.AUMW01000010_gene1055	9.15e-48	180.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,261IR@186807|Peptococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
TH3_k127_2532661_14	1189620.AJXL01000002_gene1866	6.668e-19	95.0	COG2032@1|root,COG2032@2|Bacteria,4NGGW@976|Bacteroidetes,1HY8P@117743|Flavobacteriia,2NYDV@237|Flavobacterium	976|Bacteroidetes	P	superoxide dismutase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
TH3_k127_2532661_17	1089545.KB913037_gene8972	1.017e-06	58.0	COG3794@1|root,COG3794@2|Bacteria,2H73G@201174|Actinobacteria,4E2Z7@85010|Pseudonocardiales	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
TH3_k127_2532661_12	497964.CfE428DRAFT_3521	7.476e-28	132.0	COG2010@1|root,COG2010@2|Bacteria,46TD5@74201|Verrucomicrobia	2|Bacteria	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
TH3_k127_2532661_5	452637.Oter_2583	7.462e-83	283.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	omcI	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
TH3_k127_2532661_10	452637.Oter_0299	1.663e-45	170.0	COG1595@1|root,COG1595@2|Bacteria,46VX9@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_2532661_13	452637.Oter_0300	1.124e-22	108.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF3379
TH3_k127_2532661_16	278957.ABEA03000106_gene1817	9.457e-07	60.0	COG4968@1|root,COG4968@2|Bacteria,46Y7B@74201|Verrucomicrobia,3K91Z@414999|Opitutae	414999|Opitutae	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2532661_0	497964.CfE428DRAFT_5324	0.0	1109.0	COG0495@1|root,COG0495@2|Bacteria,46SF4@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
TH3_k127_2532661_3	497964.CfE428DRAFT_2087	7.675e-103	345.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,46SDC@74201|Verrucomicrobia	74201|Verrucomicrobia	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11,Methyltransf_31
TH3_k127_2532661_2	497964.CfE428DRAFT_2088	1.208e-195	615.0	COG0192@1|root,COG0192@2|Bacteria,46S4V@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
TH3_k127_2532661_1	1235457.C404_23485	4.613e-234	732.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2VH57@28216|Betaproteobacteria,1K11D@119060|Burkholderiaceae	28216|Betaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
TH3_k127_2553185_9	1122927.KB895419_gene2361	3.36e-09	70.0	COG1413@1|root,COG5285@1|root,COG1413@2|Bacteria,COG5285@2|Bacteria,1VR7M@1239|Firmicutes,4HT83@91061|Bacilli,26SSU@186822|Paenibacillaceae	91061|Bacilli	CQ	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,PhyH
TH3_k127_2553185_7	344747.PM8797T_21598	2.164e-96	346.0	COG1520@1|root,COG1520@2|Bacteria,2IXCF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
TH3_k127_2553185_11	62928.azo2980	4.346e-05	49.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VQ32@28216|Betaproteobacteria,2KW7F@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
TH3_k127_2553185_8	335543.Sfum_1481	8.285e-20	93.0	2DRBR@1|root,33B4T@2|Bacteria,1NHJT@1224|Proteobacteria,43EE5@68525|delta/epsilon subdivisions,2WSXG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
TH3_k127_2553185_3	177437.HRM2_38050	1.252e-138	449.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria,2MJ9S@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
TH3_k127_2553185_1	497964.CfE428DRAFT_1137	0.0	1034.0	COG0282@1|root,COG4869@1|root,COG0282@2|Bacteria,COG4869@2|Bacteria,46SKB@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase,PTAC,cNMP_binding
TH3_k127_2553185_5	1449049.JONW01000013_gene4657	1.109e-117	407.0	COG5164@1|root,COG5164@2|Bacteria,1MX1Z@1224|Proteobacteria,2TWHE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2553185_0	1038860.AXAP01000015_gene2094	0.0	1435.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2TU2E@28211|Alphaproteobacteria,3JRH2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	aldehyde-lyase activity	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
TH3_k127_2553185_2	530564.Psta_1162	2.943e-291	898.0	COG3119@1|root,COG3119@2|Bacteria,2IYNT@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
TH3_k127_2553185_10	1396141.BATP01000001_gene5330	2.672e-08	55.0	28HMZ@1|root,2Z7WD@2|Bacteria,46TFX@74201|Verrucomicrobia,2IVCD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
TH3_k127_2553185_6	530564.Psta_2284	1.985e-105	351.0	COG1611@1|root,COG1611@2|Bacteria,2IZCH@203682|Planctomycetes	203682|Planctomycetes	NOU	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
TH3_k127_2553185_4	497964.CfE428DRAFT_4407	3.865e-126	409.0	COG0205@1|root,COG0205@2|Bacteria	2|Bacteria	G	6-phosphofructokinase activity	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
TH3_k127_2554409_0	382464.ABSI01000013_gene1636	1.946e-84	286.0	COG0123@1|root,COG0123@2|Bacteria,46SMT@74201|Verrucomicrobia,2IUMK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
TH3_k127_2554409_1	525904.Tter_2300	4.556e-36	142.0	COG4276@1|root,COG4276@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	Polyketide_cyc
TH3_k127_2554409_3	316274.Haur_4856	1.564e-11	79.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	quiC	-	4.2.1.118	ko:K09483	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R01627	RC00568	ko00000,ko00001,ko01000	-	-	-	Beta_helix,CHU_C,NosD
TH3_k127_2554409_2	314230.DSM3645_11946	3.84e-14	83.0	COG2165@1|root,COG2165@2|Bacteria,2J2C8@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_2559444_8	344747.PM8797T_07909	2.973e-15	86.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_2559444_5	744872.Spica_1624	5.066e-37	148.0	COG0187@1|root,COG0187@2|Bacteria,2J6PT@203691|Spirochaetes	203691|Spirochaetes	L	DNA topoisomerase	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TH3_k127_2559444_3	1121957.ATVL01000014_gene1459	3.402e-134	466.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2559444_0	1480694.DC28_14620	2.484e-220	702.0	COG0187@1|root,COG0187@2|Bacteria,2J6PT@203691|Spirochaetes	203691|Spirochaetes	L	DNA topoisomerase	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TH3_k127_2559444_6	452637.Oter_0650	4.443e-25	120.0	COG4726@1|root,COG4726@2|Bacteria,46YMK@74201|Verrucomicrobia,3K9UG@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2559444_4	452637.Oter_2787	4.096e-50	191.0	COG0739@1|root,COG0739@2|Bacteria,46V20@74201|Verrucomicrobia,3K74E@414999|Opitutae	414999|Opitutae	M	Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TH3_k127_2559444_9	661478.OP10G_0968	9.294e-15	85.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_2559444_2	272123.Anacy_2354	6.358e-143	467.0	COG0436@1|root,COG0436@2|Bacteria,1G0M8@1117|Cyanobacteria,1HIFU@1161|Nostocales	1117|Cyanobacteria	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TH3_k127_2559444_10	555079.Toce_2158	1.698e-05	54.0	2E2B7@1|root,32XGJ@2|Bacteria,1UPQ4@1239|Firmicutes,25HKV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2559444_1	886293.Sinac_7036	7.199e-176	559.0	COG4299@1|root,COG4299@2|Bacteria,2IX5Y@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2559444_7	1121430.JMLG01000019_gene1642	1.805e-17	89.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_2560336_9	1304885.AUEY01000038_gene2556	3.426e-28	118.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42Q3J@68525|delta/epsilon subdivisions,2WP5U@28221|Deltaproteobacteria,2MKDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,YwqJ-deaminase
TH3_k127_2560336_1	28072.Nos7524_1733	2.073e-221	697.0	COG3259@1|root,COG3259@2|Bacteria,1G1C8@1117|Cyanobacteria,1HMGB@1161|Nostocales	1117|Cyanobacteria	C	Coenzyme F420-reducing hydrogenase, alpha subunit	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	iJN678.hoxH	NiFeSe_Hases
TH3_k127_2560336_4	1173028.ANKO01000017_gene241	4.467e-70	249.0	COG1941@1|root,COG1941@2|Bacteria,1G2I6@1117|Cyanobacteria,1H9X3@1150|Oscillatoriales	1117|Cyanobacteria	C	Coenzyme F420-reducing hydrogenase, gamma subunit	hoxY	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	iJN678.hoxY	Oxidored_q6
TH3_k127_2560336_3	1173028.ANKO01000017_gene242	7.228e-107	350.0	COG3383@1|root,COG3383@2|Bacteria,1G3GD@1117|Cyanobacteria,1H7Z2@1150|Oscillatoriales	1117|Cyanobacteria	C	NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	hoxU	-	1.6.5.3	ko:K05588	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_10,Fer4_6,Fer4_9,NADH-G_4Fe-4S_3
TH3_k127_2560336_0	98439.AJLL01000016_gene1689	6.789e-254	793.0	COG1894@1|root,COG1894@2|Bacteria,1G2KY@1117|Cyanobacteria	1117|Cyanobacteria	C	NADH ubiquinone oxidoreductase NADH-binding (51 kD) subunit	hoxF	-	1.6.5.3	ko:K05587	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
TH3_k127_2560336_5	251229.Chro_1157	1.242e-67	235.0	COG1905@1|root,COG1905@2|Bacteria,1G54V@1117|Cyanobacteria,3VJR9@52604|Pleurocapsales	1117|Cyanobacteria	C	PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit	hoxE	-	1.6.5.3	ko:K05586	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx
TH3_k127_2560336_8	497964.CfE428DRAFT_3286	1.112e-49	198.0	COG1928@1|root,COG1928@2|Bacteria,46UW1@74201|Verrucomicrobia	74201|Verrucomicrobia	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2560336_2	1403819.BATR01000044_gene1265	8.216e-149	483.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,2ITIG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TH3_k127_2560336_7	452637.Oter_2441	6.927e-60	216.0	COG0284@1|root,COG0284@2|Bacteria,46T17@74201|Verrucomicrobia,3K7VT@414999|Opitutae	414999|Opitutae	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
TH3_k127_2560336_6	1403819.BATR01000104_gene3620	6.883e-63	223.0	COG0141@1|root,COG0141@2|Bacteria,46SHG@74201|Verrucomicrobia,2ITG9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
TH3_k127_2569305_13	661478.OP10G_3900	5.008e-18	85.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	bla1	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
TH3_k127_2569305_12	313628.LNTAR_13872	1.845e-20	102.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K16919	ko02010,map02010	M00254,M00584	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
TH3_k127_2569305_7	1142394.PSMK_15610	2.821e-40	170.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TH3_k127_2569305_9	1487923.DP73_10970	1.05e-33	141.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
TH3_k127_2569305_11	1125863.JAFN01000001_gene727	1.726e-27	125.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
TH3_k127_2569305_1	313628.LNTAR_12671	4.539e-185	600.0	COG2217@1|root,COG2217@2|Bacteria	2|Bacteria	P	Heavy metal translocating P-type atpase	cadA	-	3.6.3.3,3.6.3.5,3.6.3.54	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5,3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
TH3_k127_2569305_4	313628.LNTAR_12676	1.163e-109	367.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_2569305_16	383372.Rcas_3764	7.552e-06	58.0	COG1277@1|root,COG1277@2|Bacteria,2G79P@200795|Chloroflexi	200795|Chloroflexi	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
TH3_k127_2569305_8	313628.LNTAR_20703	2.783e-39	166.0	COG3147@1|root,COG3147@2|Bacteria	2|Bacteria	S	peptidoglycan binding	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DUF3108,SPOR
TH3_k127_2569305_10	867903.ThesuDRAFT_02283	2.717e-30	128.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WCD6@538999|Clostridiales incertae sedis	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
TH3_k127_2569305_2	227086.JGI_V11_88467	2.524e-133	437.0	COG0790@1|root,KOG1550@2759|Eukaryota	227086.JGI_V11_88467|-	T	ERAD pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2569305_14	395494.Galf_1566	2.18e-15	78.0	COG0790@1|root,COG3087@1|root,COG0790@2|Bacteria,COG3087@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	PFAM Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	SPOR,Sel1
TH3_k127_2569305_0	1396141.BATP01000005_gene6065	1.094e-189	622.0	COG0272@1|root,COG0272@2|Bacteria,46TMK@74201|Verrucomicrobia,2ITPR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	-	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
TH3_k127_2569305_3	1123277.KB893211_gene4412	1.117e-130	438.0	COG4409@1|root,COG4409@2|Bacteria,4NIJX@976|Bacteroidetes,47MH2@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TH3_k127_2569305_6	1123278.KB893448_gene1541	6.028e-55	198.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
TH3_k127_2569305_5	1410653.JHVC01000018_gene2284	1.222e-94	329.0	COG1404@1|root,COG1404@2|Bacteria,1VD5C@1239|Firmicutes,24C2E@186801|Clostridia,36H8D@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TH3_k127_2569305_15	861299.J421_1539	5.959e-06	59.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1ZURP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Tricorn protease C1 domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_S41,Tricorn_C1
TH3_k127_2571814_32	240016.ABIZ01000001_gene5918	4.788e-15	83.0	2DS4P@1|root,33EH8@2|Bacteria,46XKS@74201|Verrucomicrobia,2IW5C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2571814_26	314230.DSM3645_07370	2.259e-49	194.0	295WE@1|root,2ZT7B@2|Bacteria,2J2RS@203682|Planctomycetes	203682|Planctomycetes	S	Membrane bound O-acyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT_2
TH3_k127_2571814_36	710687.KI912270_gene983	6.737e-12	72.0	COG3011@1|root,COG3011@2|Bacteria,2HS35@201174|Actinobacteria,23ABV@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
TH3_k127_2571814_21	1120999.JONM01000003_gene2723	6.019e-63	220.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,2VQNT@28216|Betaproteobacteria,2KQ5T@206351|Neisseriales	206351|Neisseriales	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
TH3_k127_2571814_5	760192.Halhy_6811	1.276e-164	530.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,1IRRQ@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TH3_k127_2571814_12	472759.Nhal_0193	1.951e-112	406.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1WXFQ@135613|Chromatiales	135613|Chromatiales	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
TH3_k127_2571814_35	1122179.KB890464_gene358	1.323e-13	86.0	COG4733@1|root,COG5295@1|root,COG4733@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,Flg_new,He_PIG
TH3_k127_2571814_2	240016.ABIZ01000001_gene1979	2.101e-187	610.0	COG0119@1|root,COG0119@2|Bacteria,46S6Z@74201|Verrucomicrobia,2ITQ0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	LeuA allosteric (dimerisation) domain	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
TH3_k127_2571814_27	879212.DespoDRAFT_01625	1.889e-40	153.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,42W76@68525|delta/epsilon subdivisions,2WSHJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
TH3_k127_2571814_0	1396141.BATP01000007_gene5676	3.983e-282	904.0	COG0525@1|root,COG0525@2|Bacteria,46SGP@74201|Verrucomicrobia,2IU1F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
TH3_k127_2571814_33	1189619.pgond44_10131	4.967e-14	81.0	2DQHD@1|root,32UP4@2|Bacteria,4NTMT@976|Bacteroidetes,1I9JV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2571814_1	861299.J421_1753	1.227e-272	884.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
TH3_k127_2571814_17	2754.EH55_07830	4.306e-82	284.0	COG0052@1|root,COG0052@2|Bacteria,3T9UZ@508458|Synergistetes	508458|Synergistetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
TH3_k127_2571814_15	497964.CfE428DRAFT_2907	1.964e-89	302.0	COG0264@1|root,COG0264@2|Bacteria,46SUK@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
TH3_k127_2571814_3	497964.CfE428DRAFT_6681	2.711e-184	589.0	COG0535@1|root,COG0535@2|Bacteria,46V38@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF3463)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Radical_SAM
TH3_k127_2571814_9	357804.Ping_3708	5.453e-118	393.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,2QJ8J@267894|Psychromonadaceae	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	VP1997	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TH3_k127_2571814_10	472759.Nhal_3356	1.527e-115	385.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1WXP0@135613|Chromatiales	135613|Chromatiales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TH3_k127_2571814_25	65093.PCC7418_1588	4.193e-55	201.0	2EWKK@1|root,33PYP@2|Bacteria,1GC1A@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2571814_8	1173263.Syn7502_02619	6.382e-126	413.0	COG2189@1|root,COG2189@2|Bacteria,1G2XK@1117|Cyanobacteria,1H2TB@1129|Synechococcus	1117|Cyanobacteria	H	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
TH3_k127_2571814_18	1198232.CYCME_1216	1.094e-75	259.0	COG1715@1|root,COG1715@2|Bacteria,1R2JZ@1224|Proteobacteria,1T5RK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2571814_28	215803.DB30_8826	2.985e-29	124.0	28H95@1|root,2Z7KY@2|Bacteria,1RA0C@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
TH3_k127_2571814_24	272123.Anacy_0345	2.378e-59	213.0	COG5483@1|root,COG5483@2|Bacteria,1G5J1@1117|Cyanobacteria,1HP7V@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
TH3_k127_2571814_22	1121004.ATVC01000068_gene1663	2.528e-61	217.0	COG5483@1|root,COG5483@2|Bacteria,1RDGV@1224|Proteobacteria,2VV76@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
TH3_k127_2571814_30	1121004.ATVC01000068_gene1664	1.158e-17	93.0	2DQR1@1|root,32UPK@2|Bacteria,1NKZE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2571814_16	765911.Thivi_0930	6.975e-85	289.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1WXIC@135613|Chromatiales	135613|Chromatiales	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_2571814_19	580332.Slit_2080	6.521e-75	272.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria,44V3R@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
TH3_k127_2571814_7	497964.CfE428DRAFT_5498	2.613e-145	474.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	cefD	-	5.1.1.17	ko:K04127,ko:K11325,ko:K21174	ko00311,ko01059,ko01100,ko01130,map00311,map01059,map01100,map01130	M00673,M00825	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
TH3_k127_2571814_23	485918.Cpin_3102	7.42e-60	214.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1ITQW@117747|Sphingobacteriia	976|Bacteroidetes	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_2571814_6	1396141.BATP01000029_gene2231	2.774e-159	542.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
TH3_k127_2571814_11	521674.Plim_1708	7.091e-114	381.0	COG1793@1|root,COG1793@2|Bacteria,2J0I2@203682|Planctomycetes	203682|Planctomycetes	L	secreted glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_2571814_14	497964.CfE428DRAFT_0981	3.417e-106	354.0	COG2133@1|root,COG2133@2|Bacteria,46V3J@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
TH3_k127_2571814_4	240016.ABIZ01000001_gene5946	5.868e-175	561.0	COG0673@1|root,COG0673@2|Bacteria,46U0A@74201|Verrucomicrobia,2IWJK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_2571814_34	335543.Sfum_0069	6.835e-14	84.0	COG1357@1|root,COG2201@1|root,COG1357@2|Bacteria,COG2201@2|Bacteria	2|Bacteria	NT	protein-glutamate methylesterase activity	cheB	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413,ko:K18876	ko02020,ko02030,ko04626,map02020,map02030,map04626	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,DDE_5,Response_reg,TAL_effector
TH3_k127_2571814_38	706587.Desti_1174	1.581e-06	60.0	COG2204@1|root,COG2204@2|Bacteria,1RKC4@1224|Proteobacteria,42SJ3@68525|delta/epsilon subdivisions,2WPI1@28221|Deltaproteobacteria,2MRU7@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TH3_k127_2571814_37	378806.STAUR_0706	1.051e-09	70.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X7B6@28221|Deltaproteobacteria,2YUAZ@29|Myxococcales	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	FHA,HTH_8,Sigma54_activat,Yop-YscD_cpl
TH3_k127_2571814_31	278957.ABEA03000004_gene4536	1.507e-16	89.0	COG2165@1|root,COG2165@2|Bacteria,46YQC@74201|Verrucomicrobia,3K9ZW@414999|Opitutae	414999|Opitutae	U	N-terminal cleavage protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_2571814_13	1123399.AQVE01000001_gene684	2.462e-111	396.0	COG3291@1|root,COG5295@1|root,COG3291@2|Bacteria,COG5295@2|Bacteria,1RGWM@1224|Proteobacteria,1SKIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	UW	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_3
TH3_k127_2571814_29	869213.JCM21142_72843	3.442e-24	120.0	COG1404@1|root,COG3210@1|root,COG1404@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K15125,ko:K21449	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536,ko02000	1.B.40.2	-	-	5_nucleotid_C,CW_binding_2,Fil_haemagg,Haemagg_act,He_PIG,HemolysinCabind,LTD,Metallophos,PATR
TH3_k127_2571814_39	1121373.KB903654_gene1652	5.125e-05	57.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	ydcK	-	5.4.2.9	ko:K01841	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R00661	RC02792	ko00000,ko00001,ko01000	-	-	-	CBM_35,NTP_transf_3,PEP_mutase
TH3_k127_2571814_20	1396418.BATQ01000160_gene4912	2.861e-68	246.0	COG3547@1|root,COG3547@2|Bacteria,46WNP@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
TH3_k127_2617900_0	335543.Sfum_2246	5.297e-249	777.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2MRHY@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
TH3_k127_2617900_4	1396418.BATQ01000125_gene5129	9.4e-23	104.0	COG4566@1|root,COG4566@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K14987	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
TH3_k127_2617900_2	1353531.AZNX01000006_gene5683	2.305e-60	217.0	COG4566@1|root,COG4566@2|Bacteria,1RDKT@1224|Proteobacteria,2U7ZD@28211|Alphaproteobacteria,4BM44@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	PFAM Response regulator receiver domain, Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_2617900_1	335543.Sfum_0581	7.698e-96	334.0	COG2202@1|root,COG2984@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2984@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS_3
TH3_k127_2617900_3	684949.ATTJ01000002_gene171	2.206e-28	131.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8
TH3_k127_2621929_0	926550.CLDAP_04870	7.839e-118	413.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
TH3_k127_2621929_1	521674.Plim_1473	1.253e-29	123.0	COG0515@1|root,COG0515@2|Bacteria,2J50A@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Serine threonine protein kinase-related	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,dCache_1
TH3_k127_2632734_10	1123508.JH636439_gene737	1.112e-77	269.0	COG1409@1|root,COG1409@2|Bacteria	1123508.JH636439_gene737|-	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2632734_16	382464.ABSI01000005_gene1100	8.784e-38	147.0	COG0735@1|root,COG0735@2|Bacteria,46W8N@74201|Verrucomicrobia,2IUJS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
TH3_k127_2632734_1	234267.Acid_7699	3.337e-266	824.0	COG0719@1|root,COG0719@2|Bacteria,3Y2IX@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
TH3_k127_2632734_8	945713.IALB_2894	4.601e-113	370.0	COG0396@1|root,COG0396@2|Bacteria	2|Bacteria	O	ATPase activity	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	ABC_tran
TH3_k127_2632734_22	756272.Plabr_0281	4.123e-12	76.0	COG4968@1|root,COG4968@2|Bacteria,2J53J@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_2632734_12	497964.CfE428DRAFT_5027	1.803e-74	270.0	COG1520@1|root,COG1520@2|Bacteria,46U9S@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_2632734_23	661478.OP10G_4109	1.019e-11	76.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_2632734_18	794903.OPIT5_05580	2.242e-24	110.0	COG0597@1|root,COG0597@2|Bacteria,46TCC@74201|Verrucomicrobia,3K87P@414999|Opitutae	414999|Opitutae	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
TH3_k127_2632734_9	497964.CfE428DRAFT_0417	6.949e-85	291.0	COG0564@1|root,COG0564@2|Bacteria,46SQY@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TH3_k127_2632734_19	555088.DealDRAFT_2373	8.506e-23	106.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,42K3B@68298|Syntrophomonadaceae	186801|Clostridia	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_2632734_0	886293.Sinac_0430	0.0	1429.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXGT@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080
TH3_k127_2632734_11	1120999.JONM01000010_gene4084	5.002e-76	263.0	COG3142@1|root,COG3142@2|Bacteria,1MV5W@1224|Proteobacteria,2VMCV@28216|Betaproteobacteria,2KSDG@206351|Neisseriales	206351|Neisseriales	P	CutC family	-	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
TH3_k127_2632734_5	1121403.AUCV01000047_gene1054	2.448e-135	449.0	COG1028@1|root,COG1028@2|Bacteria,1MWC8@1224|Proteobacteria	1224|Proteobacteria	IQ	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2632734_4	497964.CfE428DRAFT_0118	6.631e-148	482.0	COG1972@1|root,COG1972@2|Bacteria,46S7I@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Na dependent nucleoside transporter domain protein	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
TH3_k127_2632734_17	1123368.AUIS01000006_gene589	4.04e-32	135.0	2AKF7@1|root,31B6Q@2|Bacteria,1N34J@1224|Proteobacteria,1SHID@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2632734_24	443255.SCLAV_p0644	0.0002257	57.0	COG1361@1|root,COG1750@1|root,COG1361@2|Bacteria,COG1750@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,Lon_C
TH3_k127_2632734_2	864051.BurJ1DRAFT_3700	1.329e-235	822.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
TH3_k127_2632734_13	756067.MicvaDRAFT_5451	4.632e-73	285.0	COG1361@1|root,COG2931@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1G463@1117|Cyanobacteria,1H97Y@1150|Oscillatoriales	1117|Cyanobacteria	MQ	PFAM Collagen-binding surface protein Cna-like, B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,SdrD_B
TH3_k127_2632734_3	497964.CfE428DRAFT_2621	3.562e-165	529.0	COG1030@1|root,COG1030@2|Bacteria,46TAS@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,SDH_sah
TH3_k127_2632734_7	497964.CfE428DRAFT_2620	6.779e-118	385.0	COG0330@1|root,COG0330@2|Bacteria,46VDU@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TH3_k127_2632734_20	278957.ABEA03000149_gene4042	5.435e-19	88.0	2BGYY@1|root,32AZ2@2|Bacteria,46ZHP@74201|Verrucomicrobia,3K9QU@414999|Opitutae	414999|Opitutae	S	Zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
TH3_k127_2632734_21	1484460.JSWG01000009_gene451	1.379e-12	77.0	COG2356@1|root,COG2374@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,4NINJ@976|Bacteroidetes,1HZEY@117743|Flavobacteriia	976|Bacteroidetes	L	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	LTD
TH3_k127_2632734_14	1232410.KI421415_gene3077	9.357e-73	254.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,43S5I@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
TH3_k127_2632734_6	382464.ABSI01000011_gene3025	2.674e-131	428.0	COG1186@1|root,COG1186@2|Bacteria,46SAW@74201|Verrucomicrobia,2ITHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TH3_k127_2632734_15	358396.C445_20550	1.571e-55	205.0	COG0451@1|root,arCOG03095@2157|Archaea,2XTPI@28890|Euryarchaeota,23STT@183963|Halobacteria	183963|Halobacteria	M	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
TH3_k127_2656618_5	1123371.ATXH01000016_gene1829	1.648e-89	313.0	COG2204@1|root,COG2204@2|Bacteria,2GH05@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TH3_k127_2656618_9	391623.TERMP_00885	1.29e-46	178.0	COG0463@1|root,arCOG00895@2157|Archaea,2Y66T@28890|Euryarchaeota,2454F@183968|Thermococci	183968|Thermococci	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TH3_k127_2656618_14	47839.CCAU010000018_gene4176	0.000313	53.0	COG2244@1|root,COG2244@2|Bacteria,2I8M1@201174|Actinobacteria,2372Z@1762|Mycobacteriaceae	201174|Actinobacteria	S	polysaccharide biosynthetic process	-	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2656618_6	479434.Sthe_2210	1.556e-75	267.0	COG0624@1|root,COG0624@2|Bacteria,2G8FI@200795|Chloroflexi,27XZ7@189775|Thermomicrobia	200795|Chloroflexi	E	TIGRFAM acetylornithine deacetylase or succinyl- diaminopimelate desuccinylase	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
TH3_k127_2656618_4	1232410.KI421415_gene3062	1.871e-103	345.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2WJMZ@28221|Deltaproteobacteria,43U74@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	uge	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
TH3_k127_2656618_2	880070.Cycma_3617	6.937e-129	434.0	2DBT1@1|root,2ZAV2@2|Bacteria,4NK57@976|Bacteroidetes,47XPG@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2656618_3	497964.CfE428DRAFT_2622	1.261e-127	414.0	COG0152@1|root,COG0152@2|Bacteria,46SIP@74201|Verrucomicrobia	74201|Verrucomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
TH3_k127_2656618_8	1122149.BACN01000037_gene1000	3.565e-66	238.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,3F3V9@33958|Lactobacillaceae	91061|Bacilli	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
TH3_k127_2656618_12	498761.HM1_0137	1.75e-26	128.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
TH3_k127_2656618_7	886293.Sinac_4934	1.069e-70	271.0	COG3420@1|root,COG3420@2|Bacteria,2J2YS@203682|Planctomycetes	203682|Planctomycetes	P	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2656618_13	661367.LLO_1892	4.837e-25	123.0	COG3250@1|root,COG4733@1|root,COG5492@1|root,COG3250@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Malectin,fn3
TH3_k127_2656618_1	1232410.KI421425_gene1538	1.248e-165	546.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42R8H@68525|delta/epsilon subdivisions,2WMWF@28221|Deltaproteobacteria,43T80@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	PEGA,Plug,TonB_dep_Rec
TH3_k127_2656618_10	269799.Gmet_1668	6.281e-44	166.0	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,42UIS@68525|delta/epsilon subdivisions,2WR4F@28221|Deltaproteobacteria,43VIR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
TH3_k127_2656618_0	497964.CfE428DRAFT_6499	8.199e-177	584.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,MEDS,PAS_4,PAS_9,Response_reg
TH3_k127_2656618_11	497964.CfE428DRAFT_0286	5.799e-41	153.0	2DR28@1|root,339V9@2|Bacteria	2|Bacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
TH3_k127_2663266_2	324602.Caur_0300	5.973e-11	70.0	290K2@1|root,2ZN8K@2|Bacteria,2G9HM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2663266_1	324602.Caur_0299	3.86e-18	99.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
TH3_k127_2663266_3	324602.Caur_0300	1.82e-09	64.0	290K2@1|root,2ZN8K@2|Bacteria,2G9HM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_268482_19	357808.RoseRS_1546	2.443e-11	77.0	COG4447@1|root,COG4447@2|Bacteria,2G66V@200795|Chloroflexi,3767C@32061|Chloroflexia	32061|Chloroflexia	G	glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_268482_17	452637.Oter_3887	8.443e-18	84.0	COG0644@1|root,COG1145@1|root,COG0644@2|Bacteria,COG1145@2|Bacteria,46WP0@74201|Verrucomicrobia	74201|Verrucomicrobia	C	oxidoreductase	-	-	1.5.5.1	ko:K00311,ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
TH3_k127_268482_16	794903.OPIT5_30315	1.445e-21	101.0	COG5499@1|root,COG5499@2|Bacteria	2|Bacteria	K	transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
TH3_k127_268482_18	794903.OPIT5_30320	5.488e-17	84.0	COG4680@1|root,COG4680@2|Bacteria	2|Bacteria	K	protein conserved in bacteria	higB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0043487,GO:0043488,GO:0044237,GO:0044238,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0061013,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1903311,GO:2000112,GO:2000113	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
TH3_k127_268482_3	452637.Oter_3887	1.697e-295	921.0	COG0644@1|root,COG1145@1|root,COG0644@2|Bacteria,COG1145@2|Bacteria,46WP0@74201|Verrucomicrobia	74201|Verrucomicrobia	C	oxidoreductase	-	-	1.5.5.1	ko:K00311,ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
TH3_k127_268482_0	452637.Oter_4534	0.0	1822.0	COG0458@1|root,COG0458@2|Bacteria,46UZV@74201|Verrucomicrobia,3K7MQ@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
TH3_k127_268482_1	234267.Acid_0094	0.0	1065.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	fadE23	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TH3_k127_268482_2	497964.CfE428DRAFT_4764	3.554e-305	960.0	COG0178@1|root,COG0178@2|Bacteria,46SAF@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
TH3_k127_268482_21	479435.Kfla_5346	0.0008199	48.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
TH3_k127_268482_12	1173026.Glo7428_0895	2.739e-69	240.0	COG2110@1|root,COG2110@2|Bacteria,1G5VN@1117|Cyanobacteria	1117|Cyanobacteria	S	phosphatase, C-terminal domain of histone macro H2A1 like protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
TH3_k127_268482_4	1123242.JH636435_gene2138	7.579e-136	458.0	COG0673@1|root,COG0673@2|Bacteria,2IX05@203682|Planctomycetes	203682|Planctomycetes	S	NADH-dependent dyhydrogenase related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_268482_11	497964.CfE428DRAFT_3429	1.752e-69	261.0	COG0542@1|root,COG0542@2|Bacteria,46SD6@74201|Verrucomicrobia	74201|Verrucomicrobia	O	AAA ATPase central domain protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
TH3_k127_268482_14	189425.PGRAT_14910	2.082e-42	167.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,4H9KJ@91061|Bacilli,26STY@186822|Paenibacillaceae	91061|Bacilli	G	sugar phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_268482_20	1280947.HY30_08240	4.081e-11	74.0	COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,2TR27@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	MA20_19820	-	-	-	-	-	-	-	-	-	-	-	EamA
TH3_k127_268482_13	497964.CfE428DRAFT_5399	9.218e-68	248.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
TH3_k127_268482_8	497964.CfE428DRAFT_5400	5.344e-92	308.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_268482_9	497964.CfE428DRAFT_5401	1.681e-90	316.0	COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TH3_k127_268482_10	497964.CfE428DRAFT_5401	1.098e-81	289.0	COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TH3_k127_268482_5	1396141.BATP01000023_gene554	3.96e-112	387.0	COG2340@1|root,COG2340@2|Bacteria,46VC3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
TH3_k127_268482_7	177439.DP0005	6.157e-99	329.0	COG0106@1|root,COG0106@2|Bacteria,1R6J2@1224|Proteobacteria,43B0N@68525|delta/epsilon subdivisions,2X6EQ@28221|Deltaproteobacteria,2MICV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the HisA HisF family	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
TH3_k127_268482_6	290397.Adeh_1677	1.483e-101	345.0	COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,42NU5@68525|delta/epsilon subdivisions,2WJV4@28221|Deltaproteobacteria,2YX9Q@29|Myxococcales	28221|Deltaproteobacteria	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
TH3_k127_268482_15	1123229.AUBC01000001_gene1837	9.297e-36	144.0	2E61B@1|root,330QK@2|Bacteria,1N39M@1224|Proteobacteria,2U8C9@28211|Alphaproteobacteria,3JZ9V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2733016_72	4113.PGSC0003DMT400031252	0.000146	48.0	COG0071@1|root,KOG0710@2759|Eukaryota,37T95@33090|Viridiplantae,3GHMX@35493|Streptophyta,44JIG@71274|asterids	35493|Streptophyta	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
TH3_k127_2733016_24	240016.ABIZ01000001_gene3005	3.974e-82	279.0	COG2738@1|root,COG2738@2|Bacteria,46TH9@74201|Verrucomicrobia,2IUJW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
TH3_k127_2733016_46	1499967.BAYZ01000171_gene5607	1.14e-36	145.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
TH3_k127_2733016_66	1499967.BAYZ01000171_gene5607	2.273e-08	56.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
TH3_k127_2733016_57	794903.OPIT5_26490	3.779e-14	76.0	2C4M3@1|root,2ZD1R@2|Bacteria,46WTA@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_2
TH3_k127_2733016_49	1007103.AFHW01000034_gene2097	8.41e-25	107.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,26QK1@186822|Paenibacillaceae	91061|Bacilli	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
TH3_k127_2733016_41	111781.Lepto7376_0105	8.737e-40	156.0	COG1520@1|root,COG3210@1|root,COG3595@1|root,COG4995@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3595@2|Bacteria,COG4995@2|Bacteria,1G08N@1117|Cyanobacteria,1H96Q@1150|Oscillatoriales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act,P_proprotein
TH3_k127_2733016_1	1116369.KB890025_gene5278	4.195e-242	775.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,43NRM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the GcvT family	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
TH3_k127_2733016_40	521674.Plim_4045	5.157e-40	174.0	2CGJ6@1|root,31UKG@2|Bacteria,2J1GT@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2733016_18	1396418.BATQ01000046_gene6147	4.781e-94	317.0	COG1082@1|root,COG1082@2|Bacteria,46WKR@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_2733016_3	1396141.BATP01000025_gene903	1.527e-194	632.0	COG1199@1|root,COG1199@2|Bacteria,46SCS@74201|Verrucomicrobia,2ITJT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
TH3_k127_2733016_61	1303518.CCALI_00933	3.958e-12	76.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_2733016_53	926566.Terro_2606	4.368e-19	90.0	COG0640@1|root,COG0640@2|Bacteria,3Y5UV@57723|Acidobacteria,2JNP2@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
TH3_k127_2733016_62	1168289.AJKI01000035_gene3570	5.528e-12	68.0	2AD45@1|root,312SH@2|Bacteria,4PHQV@976|Bacteroidetes,2G1PE@200643|Bacteroidia,3XKFZ@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2733016_52	1056820.KB900646_gene3544	5.229e-20	92.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,2PQGZ@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
TH3_k127_2733016_21	452637.Oter_1456	4.2e-83	295.0	COG1538@1|root,COG1538@2|Bacteria,46TY1@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TH3_k127_2733016_32	452637.Oter_1455	5.366e-62	228.0	COG0845@1|root,COG0845@2|Bacteria,46US2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
TH3_k127_2733016_0	452637.Oter_1454	0.0	1374.0	COG0841@1|root,COG0841@2|Bacteria,46SER@74201|Verrucomicrobia	74201|Verrucomicrobia	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TH3_k127_2733016_28	1254432.SCE1572_38850	7.474e-80	286.0	COG0564@1|root,COG1092@1|root,COG0564@2|Bacteria,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,42Q87@68525|delta/epsilon subdivisions,2WPIN@28221|Deltaproteobacteria,2Z02J@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PseudoU_synth_2
TH3_k127_2733016_43	1183438.GKIL_2126	2.616e-37	149.0	COG1266@1|root,COG1266@2|Bacteria,1GFE4@1117|Cyanobacteria	1117|Cyanobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
TH3_k127_2733016_23	452637.Oter_3749	1.877e-82	282.0	COG3267@1|root,COG3267@2|Bacteria,46SXM@74201|Verrucomicrobia,3K91Q@414999|Opitutae	414999|Opitutae	U	Pfam:Arch_ATPase	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
TH3_k127_2733016_45	1192034.CAP_7227	5.83e-37	153.0	COG1434@1|root,COG1434@2|Bacteria,1NDJM@1224|Proteobacteria,42XJW@68525|delta/epsilon subdivisions,2WSJ3@28221|Deltaproteobacteria,2YVV6@29|Myxococcales	28221|Deltaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
TH3_k127_2733016_29	360910.BAV2339	4.428e-76	271.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHFU@28216|Betaproteobacteria,3T1SB@506|Alcaligenaceae	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TH3_k127_2733016_65	234267.Acid_3197	1.942e-08	56.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	ko:K07339	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HicA_toxin
TH3_k127_2733016_10	1492737.FEM08_10420	2.289e-141	469.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1IJTV@117743|Flavobacteriia,2NVD2@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TH3_k127_2733016_37	391596.PBAL39_10776	2.852e-46	171.0	COG3254@1|root,COG3254@2|Bacteria,4NQQ9@976|Bacteroidetes,1ISZ2@117747|Sphingobacteriia	976|Bacteroidetes	G	L-rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
TH3_k127_2733016_22	1123073.KB899241_gene3101	9.4e-83	283.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,1RMUM@1236|Gammaproteobacteria,1XCBQ@135614|Xanthomonadales	135614|Xanthomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TH3_k127_2733016_5	1121904.ARBP01000032_gene2006	1.658e-174	584.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NK1G@976|Bacteroidetes,47RDC@768503|Cytophagia	976|Bacteroidetes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726
TH3_k127_2733016_6	1142394.PSMK_04700	2.306e-167	545.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA,BCS1_N
TH3_k127_2733016_34	349521.HCH_05416	3.573e-58	214.0	COG1116@1|root,COG1116@2|Bacteria,1MWZG@1224|Proteobacteria,1RN60@1236|Gammaproteobacteria,1XJ0F@135619|Oceanospirillales	135619|Oceanospirillales	P	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
TH3_k127_2733016_38	316056.RPC_4535	3.657e-44	171.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TTR3@28211|Alphaproteobacteria,3JR5N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
TH3_k127_2733016_47	1120792.JAFV01000001_gene1790	8.432e-29	128.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2TTB8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
TH3_k127_2733016_36	1121403.AUCV01000010_gene1377	1.299e-50	199.0	COG2885@1|root,COG3221@1|root,COG2885@2|Bacteria,COG3221@2|Bacteria,1R687@1224|Proteobacteria,42ZCB@68525|delta/epsilon subdivisions,2WTSU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MP	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,OmpA
TH3_k127_2733016_56	1238190.AMQY01000023_gene441	8.174e-15	86.0	COG2304@1|root,COG2304@2|Bacteria,1RGCN@1224|Proteobacteria,1S5GI@1236|Gammaproteobacteria,1XPSH@135619|Oceanospirillales	135619|Oceanospirillales	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
TH3_k127_2733016_17	335543.Sfum_3489	4.984e-102	355.0	COG0715@1|root,COG2885@1|root,COG0715@2|Bacteria,COG2885@2|Bacteria,1QU25@1224|Proteobacteria,42YRH@68525|delta/epsilon subdivisions,2WUGB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
TH3_k127_2733016_68	1123400.KB904788_gene192	1.41e-05	58.0	COG3266@1|root,COG3266@2|Bacteria,1R0CZ@1224|Proteobacteria	1224|Proteobacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TH3_k127_2733016_70	3694.POPTR_0006s25110.1	5.46e-05	55.0	2CN88@1|root,2QUFZ@2759|Eukaryota,37NST@33090|Viridiplantae,3GD0N@35493|Streptophyta,4JGBC@91835|fabids	35493|Streptophyta	S	glycine-rich protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2733016_2	234267.Acid_2664	1.362e-201	639.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
TH3_k127_2733016_12	330214.NIDE1620	6.369e-136	441.0	COG1118@1|root,COG1118@2|Bacteria	2|Bacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008272,GO:0008509,GO:0015075,GO:0015103,GO:0015116,GO:0015318,GO:0015399,GO:0015405,GO:0015419,GO:0015698,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0072348,GO:0097159,GO:0097367,GO:0098656,GO:0098660,GO:0098661,GO:0099133,GO:1901265,GO:1901363,GO:1901682,GO:1902358	3.6.3.25,3.6.3.29	ko:K02017,ko:K02045,ko:K10112,ko:K16787	ko00920,ko02010,map00920,map02010	M00185,M00189,M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00582,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.1,3.A.1.6.3,3.A.1.8	-	iE2348C_1286.E2348C_2607,iSSON_1240.SSON_2511	ABC_tran,TOBE,TOBE_3
TH3_k127_2733016_14	1121035.AUCH01000001_gene1959	1.902e-123	404.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2VI3S@28216|Betaproteobacteria,2KV49@206389|Rhodocyclales	206389|Rhodocyclales	P	Sulfate ABC transporter inner membrane subunit CysW	-	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
TH3_k127_2733016_15	640081.Dsui_0260	6.626e-112	370.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,2VHKY@28216|Betaproteobacteria,2KV4D@206389|Rhodocyclales	206389|Rhodocyclales	P	Sulfate ABC transporter inner membrane subunit CysT	-	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
TH3_k127_2733016_8	1122236.KB905142_gene569	2.493e-149	481.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2VIQZ@28216|Betaproteobacteria,2KKVC@206350|Nitrosomonadales	206350|Nitrosomonadales	P	TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein	-	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
TH3_k127_2733016_16	935567.JAES01000014_gene1558	2.902e-102	349.0	COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria,1RS2N@1236|Gammaproteobacteria,1X2Z1@135614|Xanthomonadales	135614|Xanthomonadales	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
TH3_k127_2733016_44	497964.CfE428DRAFT_0276	3.098e-37	145.0	COG1959@1|root,COG1959@2|Bacteria,46SPI@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
TH3_k127_2733016_54	1396141.BATP01000035_gene4053	2.351e-17	96.0	29ZA9@1|root,30M8M@2|Bacteria,46XI8@74201|Verrucomicrobia,2IVZI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2733016_50	926554.KI912668_gene5115	4.792e-22	108.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TH3_k127_2733016_42	521011.Mpal_2181	1.055e-38	154.0	COG0500@1|root,arCOG01789@2157|Archaea	2157|Archaea	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TH3_k127_2733016_69	1246445.ANAY01000001_gene403	3.581e-05	56.0	COG0438@1|root,COG0438@2|Bacteria,2GNUU@201174|Actinobacteria,4EI9I@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
TH3_k127_2733016_71	491915.Aflv_2575	0.0001404	53.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,4HCKY@91061|Bacilli,21WRB@150247|Anoxybacillus	91061|Bacilli	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_16,TPR_8
TH3_k127_2733016_48	690850.Desaf_2652	9.274e-27	124.0	COG0438@1|root,COG0438@2|Bacteria,1R9QG@1224|Proteobacteria,42PQQ@68525|delta/epsilon subdivisions,2WTQJ@28221|Deltaproteobacteria,2M9KJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
TH3_k127_2733016_33	595537.Varpa_3992	2.841e-61	219.0	COG4122@1|root,COG4122@2|Bacteria,1NR4H@1224|Proteobacteria	1224|Proteobacteria	H	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2733016_55	326424.FRAAL2042	8.958e-17	90.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
TH3_k127_2733016_60	1232410.KI421412_gene245	3.412e-13	81.0	COG0535@1|root,COG0535@2|Bacteria,1RG5U@1224|Proteobacteria,42RKR@68525|delta/epsilon subdivisions,2WNUX@28221|Deltaproteobacteria,43VVF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
TH3_k127_2733016_64	491916.RHECIAT_CH0001616	1.18e-08	66.0	COG2227@1|root,COG2227@2|Bacteria,1RAQ6@1224|Proteobacteria,2U62S@28211|Alphaproteobacteria,4B9C2@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Methionine biosynthesis protein MetW	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
TH3_k127_2733016_67	1218076.BAYB01000008_gene1536	2.321e-06	60.0	COG2244@1|root,COG2244@2|Bacteria,1R6ME@1224|Proteobacteria,2VNGZ@28216|Betaproteobacteria,1K460@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Polysaccharide biosynthesis protein	rfbE	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
TH3_k127_2733016_11	452637.Oter_3990	1.134e-138	449.0	COG0451@1|root,COG0451@2|Bacteria,46TXA@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
TH3_k127_2733016_4	313624.NSP_23270	8.517e-177	559.0	COG0451@1|root,COG0451@2|Bacteria,1G0IT@1117|Cyanobacteria,1HM8T@1161|Nostocales	1117|Cyanobacteria	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
TH3_k127_2733016_27	309799.DICTH_0179	2.952e-80	281.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Pkinase,VCBS
TH3_k127_2733016_39	215803.DB30_7465	1.149e-40	156.0	2E69S@1|root,330XP@2|Bacteria,1N7XM@1224|Proteobacteria	1224|Proteobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_5
TH3_k127_2733016_35	497964.CfE428DRAFT_3476	1.206e-56	215.0	COG0457@1|root,COG0457@2|Bacteria,46TQ7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
TH3_k127_2733016_26	595536.ADVE02000001_gene2653	7.666e-81	278.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2TS7C@28211|Alphaproteobacteria,36X2F@31993|Methylocystaceae	28211|Alphaproteobacteria	H	Quinolinate phosphoribosyl transferase, N-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
TH3_k127_2733016_25	1232410.KI421415_gene2957	8.364e-82	282.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,43S1Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	HK	HTH domain	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
TH3_k127_2733016_31	497964.CfE428DRAFT_5015	1.443e-64	230.0	COG1521@1|root,COG1521@2|Bacteria,46T0X@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
TH3_k127_2733016_20	497964.CfE428DRAFT_0832	2.685e-89	303.0	COG0159@1|root,COG0159@2|Bacteria,46SK1@74201|Verrucomicrobia	74201|Verrucomicrobia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
TH3_k127_2733016_19	794903.OPIT5_30840	4.483e-91	312.0	COG0836@1|root,COG0836@2|Bacteria,46UR9@74201|Verrucomicrobia,3K7G3@414999|Opitutae	414999|Opitutae	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
TH3_k127_2733016_73	443143.GM18_1663	0.0001785	51.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_3,DUF4347,HemolysinCabind,Phosphoesterase,VCBS,fn3
TH3_k127_2733016_9	497964.CfE428DRAFT_1517	8.363e-142	474.0	COG5002@1|root,COG5002@2|Bacteria,46SJH@74201|Verrucomicrobia	74201|Verrucomicrobia	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TH3_k127_2733016_7	497964.CfE428DRAFT_1519	3.713e-158	510.0	COG2204@1|root,COG2204@2|Bacteria,46SFT@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K11384	ko02020,map02020	M00505	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TH3_k127_2733016_58	1283300.ATXB01000002_gene3058	9.308e-14	76.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
TH3_k127_2733016_13	56780.SYN_01723	7.07e-136	456.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2MQAI@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
TH3_k127_2808748_2	497964.CfE428DRAFT_1521	1.591e-65	229.0	COG0461@1|root,COG0461@2|Bacteria,46SZV@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
TH3_k127_2808748_0	497964.CfE428DRAFT_5188	8.526e-301	934.0	COG0443@1|root,COG0443@2|Bacteria,46SDM@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
TH3_k127_2808748_9	481448.Minf_2177	1.437e-34	135.0	COG0234@1|root,COG0234@2|Bacteria,46SZ8@74201|Verrucomicrobia,37GWD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
TH3_k127_2808748_1	452637.Oter_2054	5.527e-271	841.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,3K7T7@414999|Opitutae	414999|Opitutae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
TH3_k127_2808748_6	497964.CfE428DRAFT_1374	7.644e-59	222.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
TH3_k127_2808748_3	1122169.AREN01000009_gene626	4.957e-64	248.0	COG4643@1|root,COG4983@1|root,COG4643@2|Bacteria,COG4983@2|Bacteria,1N636@1224|Proteobacteria,1RZVN@1236|Gammaproteobacteria,1JD83@118969|Legionellales	118969|Legionellales	S	Protein of unknown function (DUF3987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3987
TH3_k127_2808748_5	278963.ATWD01000001_gene3347	1.601e-63	236.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,F5_F8_type_C,Pectate_lyase_3
TH3_k127_2808748_8	743299.Acife_0301	3.306e-55	208.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RMRA@1236|Gammaproteobacteria,2NDFW@225057|Acidithiobacillales	225057|Acidithiobacillales	L	DNA methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
TH3_k127_2808748_7	203275.BFO_1382	6.437e-58	219.0	COG3385@1|root,COG3385@2|Bacteria,4NXT2@976|Bacteroidetes,2FRVS@200643|Bacteroidia,2319R@171551|Porphyromonadaceae	976|Bacteroidetes	L	hmm pf01609	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
TH3_k127_2808748_10	243090.RB5356	2.82e-13	76.0	COG4968@1|root,COG4968@2|Bacteria,2J4ZS@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_2808748_11	530564.Psta_1300	1.422e-06	61.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,CW_binding_2,Calx-beta,HemolysinCabind,LTD,Metallophos,Peptidase_S8
TH3_k127_2808748_4	41431.PCC8801_4418	6.985e-64	230.0	COG2367@1|root,COG2367@2|Bacteria,1G0DG@1117|Cyanobacteria,3KFP8@43988|Cyanothece	1117|Cyanobacteria	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
TH3_k127_2849961_6	1123392.AQWL01000002_gene1978	1.689e-110	368.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KSKV@119069|Hydrogenophilales	119069|Hydrogenophilales	V	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TH3_k127_2849961_9	1238182.C882_0258	1.699e-58	222.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,2JQW0@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
TH3_k127_2849961_11	530564.Psta_0781	1.923e-17	90.0	COG1309@1|root,COG1309@2|Bacteria,2J1M7@203682|Planctomycetes	203682|Planctomycetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TH3_k127_2849961_0	468059.AUHA01000006_gene2919	1.484e-196	624.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPK3@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
TH3_k127_2849961_1	1267535.KB906767_gene3116	8.198e-176	565.0	COG0531@1|root,COG0531@2|Bacteria,3Y3QM@57723|Acidobacteria,2JKYS@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
TH3_k127_2849961_2	1031288.AXAA01000003_gene1700	8.842e-164	530.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,36FFK@31979|Clostridiaceae	186801|Clostridia	C	Na H antiporter	-	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
TH3_k127_2849961_5	404589.Anae109_0983	9.976e-153	492.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42NZ7@68525|delta/epsilon subdivisions,2WKSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
TH3_k127_2849961_4	398512.JQKC01000004_gene5249	1.376e-153	519.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,3WI29@541000|Ruminococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
TH3_k127_2849961_10	998088.B565_2515	8.391e-31	126.0	COG2249@1|root,COG2249@2|Bacteria,1MUHN@1224|Proteobacteria,1RU3S@1236|Gammaproteobacteria,1Y501@135624|Aeromonadales	135624|Aeromonadales	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
TH3_k127_2849961_12	382464.ABSI01000005_gene1380	3.587e-09	68.0	2B7DQ@1|root,320HD@2|Bacteria,46XRQ@74201|Verrucomicrobia,2IWFK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2849961_3	243090.RB7928	2.838e-154	524.0	COG0515@1|root,COG1714@1|root,COG0515@2|Bacteria,COG1714@2|Bacteria,2IY76@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RDD
TH3_k127_2849961_8	497964.CfE428DRAFT_2982	3.718e-67	239.0	COG1595@1|root,COG1595@2|Bacteria,46V3P@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
TH3_k127_2849961_7	1396418.BATQ01000160_gene4912	1.266e-67	244.0	COG3547@1|root,COG3547@2|Bacteria,46WNP@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
TH3_k127_2858162_3	497964.CfE428DRAFT_3740	4.749e-179	568.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TH3_k127_2858162_8	497964.CfE428DRAFT_3740	1.825e-15	77.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TH3_k127_2858162_2	448385.sce0471	2.339e-183	597.0	COG1414@1|root,COG1414@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	3.6.4.12	ko:K03655,ko:K10439,ko:K11708	ko02010,ko02030,ko03440,map02010,map02030,map03440	M00212,M00319	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.15,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	AlbA_2,HATPase_c_4,HTH_IclR,IclR,Peripla_BP_4,VCBS
TH3_k127_2858162_6	497964.CfE428DRAFT_2334	2.344e-46	172.0	COG1522@1|root,COG1522@2|Bacteria,46VEI@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
TH3_k127_2858162_4	452637.Oter_2839	2.113e-149	482.0	COG0436@1|root,COG0436@2|Bacteria,46SFZ@74201|Verrucomicrobia,3K7B5@414999|Opitutae	414999|Opitutae	E	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
TH3_k127_2858162_1	452637.Oter_3485	1.508e-230	739.0	COG2217@1|root,COG2217@2|Bacteria,46S53@74201|Verrucomicrobia,3K7EF@414999|Opitutae	414999|Opitutae	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
TH3_k127_2858162_7	1191523.MROS_2770	1.134e-32	135.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	usp-3	-	-	-	-	-	-	-	-	-	-	-	Usp
TH3_k127_2858162_0	497964.CfE428DRAFT_6083	2.836e-286	894.0	COG1274@1|root,COG1274@2|Bacteria,46UB8@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
TH3_k127_2858162_5	756067.MicvaDRAFT_2865	5.149e-115	382.0	COG2234@1|root,COG2234@2|Bacteria,1G1QW@1117|Cyanobacteria,1H7N7@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
TH3_k127_2858162_9	1408418.JNJH01000059_gene365	0.0002558	53.0	COG3577@1|root,COG3577@2|Bacteria	2|Bacteria	S	aspartic-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,TPR_16,gag-asp_proteas
TH3_k127_287048_5	416591.Tlet_1147	4.965e-07	54.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
TH3_k127_287048_2	555779.Dthio_PD3610	5.485e-27	115.0	2E0F6@1|root,32W1G@2|Bacteria,1N6I3@1224|Proteobacteria,42V01@68525|delta/epsilon subdivisions,2WQWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_287048_0	768671.ThimaDRAFT_3685	2.425e-177	573.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,1RQ9W@1236|Gammaproteobacteria,1WZG5@135613|Chromatiales	135613|Chromatiales	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
TH3_k127_287048_1	768671.ThimaDRAFT_3684	5.554e-99	335.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,1RPJM@1236|Gammaproteobacteria,1WYYP@135613|Chromatiales	135613|Chromatiales	L	DNA replication protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
TH3_k127_287048_4	1197906.CAJQ02000044_gene1657	3.783e-16	82.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
TH3_k127_2876595_5	886293.Sinac_0918	1.183e-173	560.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
TH3_k127_2876595_14	497964.CfE428DRAFT_4863	3.793e-110	380.0	COG0515@1|root,COG0515@2|Bacteria	497964.CfE428DRAFT_4863|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2876595_17	497964.CfE428DRAFT_4864	6.652e-77	266.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2876595_11	575540.Isop_0386	5.141e-126	419.0	COG1874@1|root,COG1874@2|Bacteria,2J0Y5@203682|Planctomycetes	203682|Planctomycetes	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832
TH3_k127_2876595_1	945713.IALB_0720	6.219e-204	670.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	fixI	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
TH3_k127_2876595_31	1313301.AUGC01000014_gene2496	5.602e-08	57.0	COG3197@1|root,COG3197@2|Bacteria	2|Bacteria	P	Cytochrome oxidase maturation protein	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
TH3_k127_2876595_0	1191523.MROS_1513	0.0	1076.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	ccoO	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600	1.9.3.1	ko:K00404,ko:K00405,ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iIT341.HP0144,iIT341.HP0145	COX1,FixO
TH3_k127_2876595_24	1191523.MROS_1515	1.13e-45	171.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
TH3_k127_2876595_8	1121930.AQXG01000002_gene2269	9.657e-161	520.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1IP29@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
TH3_k127_2876595_28	1356852.N008_20380	4.096e-24	109.0	COG3198@1|root,COG3198@2|Bacteria,4PPZ3@976|Bacteroidetes,47RV1@768503|Cytophagia	976|Bacteroidetes	S	FixH	ccoH	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
TH3_k127_2876595_21	313606.M23134_03514	7.81e-52	191.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,47QDS@768503|Cytophagia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
TH3_k127_2876595_13	1396141.BATP01000047_gene3937	2.878e-112	370.0	COG0005@1|root,COG0005@2|Bacteria,46UP8@74201|Verrucomicrobia,2ITPF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
TH3_k127_2876595_3	478741.JAFS01000001_gene2129	9.884e-192	625.0	COG2217@1|root,COG2217@2|Bacteria,46S9Z@74201|Verrucomicrobia,37FUI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	Heavy-metal-associated domain	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
TH3_k127_2876595_6	323848.Nmul_A0761	1.507e-168	542.0	COG4992@1|root,COG4992@2|Bacteria,1R6U9@1224|Proteobacteria,2VR1P@28216|Betaproteobacteria,371Z3@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3,PP-binding
TH3_k127_2876595_19	243233.MCA2757	1.509e-72	255.0	COG0385@1|root,COG0385@2|Bacteria	2|Bacteria	S	bile acid:sodium symporter activity	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
TH3_k127_2876595_20	1123258.AQXZ01000016_gene2259	1.094e-53	199.0	COG3675@1|root,COG3675@2|Bacteria,2HK7P@201174|Actinobacteria,4G7ZK@85025|Nocardiaceae	201174|Actinobacteria	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
TH3_k127_2876595_7	166318.Syn8016DRAFT_1989	9.739e-163	538.0	COG0643@1|root,COG0643@2|Bacteria,1G26V@1117|Cyanobacteria,1H46D@1129|Synechococcus	1117|Cyanobacteria	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
TH3_k127_2876595_25	931626.Awo_c04230	2.615e-40	161.0	COG0835@1|root,COG0835@2|Bacteria,1V4VQ@1239|Firmicutes,24BQT@186801|Clostridia	186801|Clostridia	NT	Chemoreceptor zinc-binding domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,CheW
TH3_k127_2876595_2	880072.Desac_2375	1.289e-202	640.0	COG2114@1|root,COG5000@1|root,COG2114@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP,HATPase_c,HD_5,HisKA,PAS,PAS_9,Response_reg,dCache_1
TH3_k127_2876595_15	880072.Desac_2374	7.011e-84	281.0	COG1719@1|root,COG1719@2|Bacteria,1RH5H@1224|Proteobacteria,42SDY@68525|delta/epsilon subdivisions,2WPEQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM 4-vinyl reductase, 4VR	-	-	-	ko:K07013	-	-	-	-	ko00000	-	-	-	V4R
TH3_k127_2876595_10	665571.STHERM_c12790	5.235e-141	463.0	COG0438@1|root,COG0438@2|Bacteria,2J6VH@203691|Spirochaetes	203691|Spirochaetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
TH3_k127_2876595_4	926550.CLDAP_09870	5.73e-182	587.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	ycjM	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
TH3_k127_2876595_22	1347392.CCEZ01000010_gene2401	8.406e-47	181.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,36EZ7@31979|Clostridiaceae	186801|Clostridia	P	K -dependent Na Ca exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
TH3_k127_2876595_30	1499967.BAYZ01000073_gene2050	3.004e-08	65.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD,HAD_2,Hydrolase,Hydrolase_like
TH3_k127_2876595_27	665571.STHERM_c16620	5.125e-25	121.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.270	ko:K21369	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TH3_k127_2876595_12	497964.CfE428DRAFT_2620	3.736e-116	379.0	COG0330@1|root,COG0330@2|Bacteria,46VDU@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TH3_k127_2876595_9	671143.DAMO_1541	2.285e-146	473.0	COG1215@1|root,COG1215@2|Bacteria,2NNSB@2323|unclassified Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
TH3_k127_2876595_23	452637.Oter_0434	7.092e-46	172.0	COG0835@1|root,COG0835@2|Bacteria,46VRE@74201|Verrucomicrobia,3K82Y@414999|Opitutae	414999|Opitutae	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
TH3_k127_2876595_16	452637.Oter_4099	1.219e-79	290.0	COG0840@1|root,COG0840@2|Bacteria,46THW@74201|Verrucomicrobia,3K9B6@414999|Opitutae	414999|Opitutae	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
TH3_k127_2876595_18	794903.OPIT5_24810	5.261e-76	264.0	COG1352@1|root,COG1352@2|Bacteria,46U98@74201|Verrucomicrobia,3K88R@414999|Opitutae	414999|Opitutae	NT	CheR methyltransferase, SAM binding domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
TH3_k127_2940010_0	448385.sce7733	0.0	1138.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria,2YX1T@29|Myxococcales	28221|Deltaproteobacteria	H	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
TH3_k127_2940010_2	240016.ABIZ01000001_gene4409	1.435e-102	341.0	COG3828@1|root,COG3828@2|Bacteria,46SV1@74201|Verrucomicrobia,2IV8Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
TH3_k127_2940010_1	1123508.JH636442_gene3931	1.206e-147	477.0	COG1506@1|root,COG1506@2|Bacteria,2IWTJ@203682|Planctomycetes	203682|Planctomycetes	E	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
TH3_k127_2940010_3	517418.Ctha_0233	2.197e-93	338.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1FDRS@1090|Chlorobi	1090|Chlorobi	C	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
TH3_k127_2955395_2	483219.LILAB_31790	2.351e-114	374.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,2YXTZ@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TH3_k127_2955395_8	1117319.PSPO_04287	3.016e-15	79.0	COG1520@1|root,COG1520@2|Bacteria,1N8KC@1224|Proteobacteria,1SF02@1236|Gammaproteobacteria,2Q4VQ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_2955395_9	1487923.DP73_02105	2.1e-13	76.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,2609M@186807|Peptococcaceae	186801|Clostridia	F	TIGRFAM Pyrimidine-nucleoside phosphorylase	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
TH3_k127_2955395_3	1121428.DESHY_40194___1	3.139e-107	354.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,248U5@186801|Clostridia,263IX@186807|Peptococcaceae	186801|Clostridia	G	Major intrinsic protein	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	iHN637.CLJU_RS07630	MIP
TH3_k127_2955395_0	243231.GSU2762	1.024e-228	719.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,42M9Z@68525|delta/epsilon subdivisions,2WIYZ@28221|Deltaproteobacteria,43U0G@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
TH3_k127_2955395_4	756272.Plabr_3925	3.94e-86	293.0	COG1028@1|root,COG1028@2|Bacteria,2IXFA@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TH3_k127_2955395_5	497964.CfE428DRAFT_6140	2.426e-82	283.0	COG0515@1|root,COG0515@2|Bacteria,46UMT@74201|Verrucomicrobia	497964.CfE428DRAFT_6140|-	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2955395_1	497964.CfE428DRAFT_0790	1.309e-187	597.0	COG3875@1|root,COG3875@2|Bacteria	2|Bacteria	S	lactate racemase activity	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
TH3_k127_2955395_7	639030.JHVA01000001_gene2022	4.005e-37	149.0	COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria,2JJME@204432|Acidobacteriia	204432|Acidobacteriia	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
TH3_k127_2955395_6	946483.Cenrod_1961	4.58e-41	157.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VMDU@28216|Betaproteobacteria,4AJA8@80864|Comamonadaceae	28216|Betaproteobacteria	L	Group II intron, maturase-specific domain	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,Intron_maturas2,RVT_1
TH3_k127_2973230_26	498761.HM1_0138	6.963e-10	72.0	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria,1UHXK@1239|Firmicutes,25E6U@186801|Clostridia	186801|Clostridia	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,Flg_new,I-set,Laminin_G_3,SLH
TH3_k127_2973230_3	1232410.KI421425_gene1538	1.192e-165	542.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42R8H@68525|delta/epsilon subdivisions,2WMWF@28221|Deltaproteobacteria,43T80@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	PEGA,Plug,TonB_dep_Rec
TH3_k127_2973230_12	1167006.UWK_00360	2.528e-66	237.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PWS@68525|delta/epsilon subdivisions,2WKI5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TPR_8,TonB_dep_Rec
TH3_k127_2973230_27	228405.HNE_2756	1.277e-06	57.0	COG0322@1|root,COG0322@2|Bacteria,1PVWI@1224|Proteobacteria,2V74B@28211|Alphaproteobacteria,4402D@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	COG0322 Nuclease subunit of the excinuclease complex	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
TH3_k127_2973230_0	448385.sce4763	8.167e-218	693.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2X37C@28221|Deltaproteobacteria,2YUQZ@29|Myxococcales	28221|Deltaproteobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
TH3_k127_2973230_15	313624.NSP_27450	5.534e-52	203.0	COG1075@1|root,COG1075@2|Bacteria,1GIQY@1117|Cyanobacteria,1HP99@1161|Nostocales	1117|Cyanobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2973230_6	573065.Astex_0235	1.431e-137	449.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,2KEYZ@204458|Caulobacterales	204458|Caulobacterales	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
TH3_k127_2973230_17	497964.CfE428DRAFT_4129	6.604e-41	155.0	COG0346@1|root,COG0346@2|Bacteria,46T5V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TH3_k127_2973230_4	382464.ABSI01000011_gene3117	9.604e-149	475.0	COG0074@1|root,COG0074@2|Bacteria,46TRM@74201|Verrucomicrobia,2ITVZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
TH3_k127_2973230_9	1173028.ANKO01000195_gene5986	2.489e-104	350.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,1G1M7@1117|Cyanobacteria,1H7YE@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,STAS
TH3_k127_2973230_2	1121017.AUFG01000010_gene1661	1.413e-174	557.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4FEQ1@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
TH3_k127_2973230_8	886293.Sinac_1763	6.992e-129	424.0	COG1830@1|root,COG1830@2|Bacteria,2IXP8@203682|Planctomycetes	203682|Planctomycetes	G	Aldolase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_2973230_11	794903.OPIT5_04235	2.804e-91	311.0	COG0235@1|root,COG0235@2|Bacteria,46UR3@74201|Verrucomicrobia,3K7W3@414999|Opitutae	414999|Opitutae	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
TH3_k127_2973230_22	278957.ABEA03000086_gene2503	2.249e-22	101.0	COG4576@1|root,COG4576@2|Bacteria,46WMY@74201|Verrucomicrobia,3K8EE@414999|Opitutae	414999|Opitutae	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
TH3_k127_2973230_23	1123242.JH636435_gene1239	3.903e-20	94.0	COG4576@1|root,COG4576@2|Bacteria,2J0UQ@203682|Planctomycetes	203682|Planctomycetes	CQ	PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
TH3_k127_2973230_1	452637.Oter_1295	4.293e-175	562.0	COG1012@1|root,COG1012@2|Bacteria,46UYV@74201|Verrucomicrobia,3K7HF@414999|Opitutae	414999|Opitutae	C	Aldehyde dehydrogenase family	-	-	-	ko:K04021	ko00620,ko01100,ko01120,map00620,map01100,map01120	-	R00228	RC00004,RC01195	ko00000,ko00001	-	-	-	Aldedh
TH3_k127_2973230_14	1403819.BATR01000059_gene1822	2.922e-55	196.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	5.3.3.19	ko:K19547	ko01130,map01130	M00787	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,HATPase_c,His_kinase,PocR
TH3_k127_2973230_18	278957.ABEA03000086_gene2506	8.742e-37	141.0	COG4576@1|root,COG4576@2|Bacteria,46VMK@74201|Verrucomicrobia,3K8BF@414999|Opitutae	414999|Opitutae	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
TH3_k127_2973230_21	794903.OPIT5_04210	5.565e-31	125.0	COG4577@1|root,COG4577@2|Bacteria,46W1J@74201|Verrucomicrobia,3K8AE@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
TH3_k127_2973230_5	794903.OPIT5_04205	1.128e-148	484.0	COG0282@1|root,COG0282@2|Bacteria,46TZF@74201|Verrucomicrobia,3K7U1@414999|Opitutae	414999|Opitutae	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
TH3_k127_2973230_19	452637.Oter_1291	2.565e-35	137.0	COG4577@1|root,COG4577@2|Bacteria,46WBA@74201|Verrucomicrobia,3K89K@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
TH3_k127_2973230_20	794903.OPIT5_04195	2.659e-33	130.0	COG4577@1|root,COG4577@2|Bacteria,46W7U@74201|Verrucomicrobia,3K8C2@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
TH3_k127_2973230_10	278957.ABEA03000087_gene601	2.807e-101	343.0	COG4869@1|root,COG4869@2|Bacteria,46UMP@74201|Verrucomicrobia,3K7FS@414999|Opitutae	414999|Opitutae	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	PTAC
TH3_k127_2973230_16	314230.DSM3645_04975	5.865e-50	188.0	COG1349@1|root,COG1349@2|Bacteria,2IYW0@203682|Planctomycetes	203682|Planctomycetes	K	COG1349 Transcriptional regulators of sugar metabolism	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
TH3_k127_2973230_7	886293.Sinac_2714	1.646e-133	441.0	COG0673@1|root,COG0673@2|Bacteria,2IXFW@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_2973230_13	240016.ABIZ01000001_gene272	2.149e-63	229.0	COG0859@1|root,COG0859@2|Bacteria,46SZK@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
TH3_k127_2973230_25	794903.OPIT5_29490	4.83e-16	86.0	2EEN4@1|root,338G1@2|Bacteria,46T5X@74201|Verrucomicrobia,3K81C@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3007978_0	653733.Selin_0475	3.618e-144	465.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_32
TH3_k127_3007978_11	497964.CfE428DRAFT_1374	1.5e-25	121.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
TH3_k127_3007978_13	497964.CfE428DRAFT_1374	3.991e-18	94.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
TH3_k127_3007978_1	497964.CfE428DRAFT_4932	2.666e-130	420.0	COG0107@1|root,COG0107@2|Bacteria,46S6V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
TH3_k127_3007978_4	452637.Oter_1490	3.599e-85	287.0	COG3417@1|root,COG3417@2|Bacteria	2|Bacteria	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
TH3_k127_3007978_6	1123508.JH636451_gene5878	2.476e-67	240.0	2DWSV@1|root,341QK@2|Bacteria,2J4FR@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3007978_2	452637.Oter_1491	3.191e-107	364.0	COG3014@1|root,COG3014@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TH3_k127_3007978_5	857087.Metme_4292	5.798e-76	269.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RNIU@1236|Gammaproteobacteria,1XH04@135618|Methylococcales	1236|Gammaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
TH3_k127_3007978_14	1411123.JQNH01000001_gene19	5.086e-18	87.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
TH3_k127_3007978_3	518766.Rmar_2306	2.411e-89	301.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1FIWZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
TH3_k127_3007978_8	497964.CfE428DRAFT_5288	3.26e-45	172.0	COG0811@1|root,COG0811@2|Bacteria,46V4I@74201|Verrucomicrobia	74201|Verrucomicrobia	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
TH3_k127_3007978_12	497964.CfE428DRAFT_5287	1.76e-21	99.0	COG0848@1|root,COG0848@2|Bacteria,46T4F@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
TH3_k127_3007978_16	335543.Sfum_0754	0.00054	51.0	COG0810@1|root,COG0810@2|Bacteria,1Q5Z4@1224|Proteobacteria,43A9M@68525|delta/epsilon subdivisions,2X230@28221|Deltaproteobacteria,2MQPN@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
TH3_k127_3007978_7	481448.Minf_2452	1.235e-56	213.0	COG0823@1|root,COG0823@2|Bacteria,46SSK@74201|Verrucomicrobia,37GCW@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	WD40-like Beta Propeller Repeat	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
TH3_k127_3007978_10	481448.Minf_2453	5.871e-30	126.0	COG2885@1|root,COG2885@2|Bacteria,46T4D@74201|Verrucomicrobia,37GNQ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	OmpA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
TH3_k127_3040882_12	1123503.KB908056_gene2238	1.065e-26	122.0	COG5340@1|root,COG5340@2|Bacteria,1R80Q@1224|Proteobacteria,2U4TW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	AbiEi antitoxin C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4
TH3_k127_3040882_2	1382359.JIAL01000001_gene1690	9.477e-177	575.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3ZP@57723|Acidobacteria,2JI7Y@204432|Acidobacteriia	204432|Acidobacteriia	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
TH3_k127_3040882_10	1121904.ARBP01000010_gene2339	1.347e-32	127.0	COG3369@1|root,COG3369@2|Bacteria,4NW9E@976|Bacteroidetes,47W0Y@768503|Cytophagia	976|Bacteroidetes	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
TH3_k127_3040882_9	1121440.AUMA01000016_gene183	7.1e-33	129.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,42VG7@68525|delta/epsilon subdivisions,2WP7R@28221|Deltaproteobacteria,2MDD2@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
TH3_k127_3040882_11	926569.ANT_30650	1.647e-30	123.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
TH3_k127_3040882_0	314230.DSM3645_24165	4.799e-192	611.0	COG0591@1|root,COG0591@2|Bacteria,2IWSN@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TH3_k127_3040882_8	180332.JTGN01000016_gene1024	2.965e-33	143.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
TH3_k127_3040882_15	697281.Mahau_2672	2.103e-09	69.0	COG0407@1|root,COG0407@2|Bacteria,1VJHK@1239|Firmicutes,24TV3@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
TH3_k127_3040882_6	761193.Runsl_2772	4.793e-50	190.0	COG0329@1|root,COG0329@2|Bacteria,4NI1I@976|Bacteroidetes,47NMJ@768503|Cytophagia	976|Bacteroidetes	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
TH3_k127_3040882_5	234267.Acid_5864	5.168e-54	202.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_3040882_1	452637.Oter_2196	2.533e-185	591.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_3040882_3	1267535.KB906767_gene3674	4.223e-130	424.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	MA20_02630	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_3040882_4	555079.Toce_1809	4.526e-54	202.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,42FIY@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM ROK family protein	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
TH3_k127_3040882_13	1096546.WYO_0029	2.235e-12	74.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,1JRB9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
TH3_k127_3040882_14	743719.PaelaDRAFT_1789	1.916e-10	72.0	COG2207@1|root,COG2207@2|Bacteria,1UMYK@1239|Firmicutes,4IU3F@91061|Bacilli,277HV@186822|Paenibacillaceae	91061|Bacilli	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
TH3_k127_3040882_7	497964.CfE428DRAFT_2773	4.864e-48	188.0	2F6K4@1|root,33Z30@2|Bacteria,46VYC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative beta-barrel porin 2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
TH3_k127_3060869_4	521674.Plim_0129	3.76e-21	106.0	COG0551@1|root,COG2010@1|root,COG0551@2|Bacteria,COG2010@2|Bacteria,2IY3X@203682|Planctomycetes	203682|Planctomycetes	CL	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
TH3_k127_3060869_1	886293.Sinac_0942	5.856e-224	704.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TH3_k127_3060869_3	448385.sce0162	1.902e-47	182.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42TDG@68525|delta/epsilon subdivisions,2WPJP@28221|Deltaproteobacteria,2Z1CP@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TH3_k127_3060869_2	595460.RRSWK_05849	4.894e-138	456.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,2J2W6@203682|Planctomycetes	203682|Planctomycetes	E	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_20,Pyr_redox_2
TH3_k127_3060869_0	595460.RRSWK_06189	2.921e-260	826.0	COG1894@1|root,COG1894@2|Bacteria,2IXJ8@203682|Planctomycetes	203682|Planctomycetes	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
TH3_k127_3075247_14	742725.HMPREF9450_00266	5.591e-68	238.0	COG3408@1|root,COG3408@2|Bacteria,4NJY8@976|Bacteroidetes,2G2N9@200643|Bacteroidia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
TH3_k127_3075247_7	926550.CLDAP_30260	4.313e-98	356.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,F5_F8_type_C,Glyco_hydro_125
TH3_k127_3075247_18	240016.ABIZ01000001_gene54	1.841e-17	83.0	COG3356@1|root,COG3356@2|Bacteria,46XH2@74201|Verrucomicrobia,2IVWJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
TH3_k127_3075247_15	373994.Riv7116_3284	2.337e-65	235.0	COG4223@1|root,COG4223@2|Bacteria	2|Bacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	elrF	-	-	-	-	-	-	-	-	-	-	-	Cutinase,DUF1350,DUF1631
TH3_k127_3075247_3	344747.PM8797T_06060	7.398e-130	431.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_3075247_20	1385935.N836_03200	1.271e-11	76.0	COG2207@1|root,COG2207@2|Bacteria,1GBJH@1117|Cyanobacteria	1117|Cyanobacteria	K	transcriptional	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Response_reg
TH3_k127_3075247_19	661478.OP10G_4770	3.169e-15	87.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_3075247_4	525904.Tter_1997	4.311e-125	409.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_3075247_0	1123508.JH636448_gene7659	5.93e-232	726.0	COG2730@1|root,COG2730@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
TH3_k127_3075247_9	344747.PM8797T_05400	3.793e-87	304.0	COG1520@1|root,COG1520@2|Bacteria,2IY8V@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
TH3_k127_3075247_8	1122917.KB899667_gene3587	8.99e-97	328.0	COG2085@1|root,COG2085@2|Bacteria,1TWYH@1239|Firmicutes	1239|Firmicutes	S	Phosphogluconate dehydrogenase (decarboxylating) C-term	-	-	-	-	-	-	-	-	-	-	-	-	IlvN,PGDH_C
TH3_k127_3075247_12	761193.Runsl_3634	3.994e-75	261.0	COG1082@1|root,COG1082@2|Bacteria,4NPBS@976|Bacteroidetes,47Q6G@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_3075247_10	1089551.KE386572_gene1625	3.168e-84	294.0	COG1879@1|root,COG1879@2|Bacteria,1QJ9B@1224|Proteobacteria,2U8ZS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
TH3_k127_3075247_16	35754.JNYJ01000079_gene4336	2.986e-45	181.0	COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria,4DDXV@85008|Micromonosporales	201174|Actinobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
TH3_k127_3075247_2	1089551.KE386572_gene1627	1.767e-165	545.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria,4BR8I@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
TH3_k127_3075247_11	1089551.KE386572_gene1628	1.347e-82	287.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2TV15@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440,ko:K17203	ko02010,map02010	M00212,M00590	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19	-	-	BPD_transp_2
TH3_k127_3075247_5	525904.Tter_2007	1.297e-124	424.0	2CB42@1|root,2Z7Y3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3075247_13	761193.Runsl_3635	1.266e-74	263.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	HemolysinCabind,PD40
TH3_k127_3075247_17	926550.CLDAP_31990	7.008e-40	159.0	COG1082@1|root,COG1082@2|Bacteria,2G7PW@200795|Chloroflexi	200795|Chloroflexi	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_3075247_1	1267533.KB906739_gene2717	5.349e-231	736.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid_C,Bgal_small_N,Glyco_hydro_2,Glyco_hydro_28,Glyco_hydro_2_C,Glyco_hydro_2_N,fn3
TH3_k127_3075247_6	616991.JPOO01000003_gene29	1.61e-99	341.0	2DDE1@1|root,2ZHNZ@2|Bacteria,4NNSM@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TH3_k127_3166288_4	1333507.AUTQ01000181_gene2364	3.657e-05	46.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
TH3_k127_3166288_5	1463825.JNXC01000053_gene31	6.221e-05	53.0	COG3507@1|root,COG3507@2|Bacteria,2I911@201174|Actinobacteria,4E0PM@85010|Pseudonocardiales	201174|Actinobacteria	G	Cellulose Binding Domain Type IV	-	-	3.2.1.55	ko:K15921	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43	-	CBM_4_9,CBM_6,Glyco_hydro_43
TH3_k127_3166288_3	1303518.CCALI_00913	7.607e-14	81.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_3166288_2	640081.Dsui_2056	7.046e-18	90.0	COG1403@1|root,COG1403@2|Bacteria,1RIEZ@1224|Proteobacteria,2VTF6@28216|Betaproteobacteria,2KWR0@206389|Rhodocyclales	206389|Rhodocyclales	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
TH3_k127_3166288_0	1229909.NSED_00255	1.166e-67	231.0	COG0432@1|root,arCOG04214@2157|Archaea,41T31@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
TH3_k127_3166288_1	497964.CfE428DRAFT_0064	6.179e-54	199.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
TH3_k127_3176565_1	530564.Psta_2754	2.901e-80	291.0	COG2755@1|root,COG2755@2|Bacteria,2IWTR@203682|Planctomycetes	2|Bacteria	E	sialic acid-specific 9-O-acetylesterase	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	SASA
TH3_k127_3176565_0	583355.Caka_2934	1.529e-126	421.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
TH3_k127_3176565_2	583355.Caka_0996	1.84e-45	172.0	COG3537@1|root,COG3537@2|Bacteria	2|Bacteria	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHB_HEX_C_1,F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b,Glyco_hydro_85,PA14
TH3_k127_319053_2	1123008.KB905693_gene1177	3.531e-112	372.0	COG3394@1|root,COG3394@2|Bacteria,4NFY5@976|Bacteroidetes	976|Bacteroidetes	G	PFAM YdjC family protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
TH3_k127_319053_1	1123242.JH636434_gene4911	1.352e-130	430.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
TH3_k127_319053_0	644966.Tmar_0705	3.278e-154	505.0	COG2936@1|root,COG2936@2|Bacteria,1TT0H@1239|Firmicutes,24BT1@186801|Clostridia,3WD7J@538999|Clostridiales incertae sedis	186801|Clostridia	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
TH3_k127_319053_4	661367.LLO_3002	1.571e-10	76.0	COG1470@1|root,COG1520@1|root,COG3291@1|root,COG4447@1|root,COG5184@1|root,COG1470@2|Bacteria,COG1520@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,COG5184@2|Bacteria,1RBUT@1224|Proteobacteria,1S27R@1236|Gammaproteobacteria,1JEPR@118969|Legionellales	118969|Legionellales	DZ	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
TH3_k127_319053_3	498761.HM1_0138	1.632e-17	94.0	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria,1UHXK@1239|Firmicutes,25E6U@186801|Clostridia	186801|Clostridia	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,Flg_new,I-set,Laminin_G_3,SLH
TH3_k127_3224340_5	344747.PM8797T_02174	1.148e-120	405.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
TH3_k127_3224340_1	344747.PM8797T_02169	5.488e-254	816.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2IXB6@203682|Planctomycetes	203682|Planctomycetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos,Methyltransf_25,PQQ_2
TH3_k127_3224340_8	203275.BFO_2526	2.607e-44	164.0	COG3254@1|root,COG3254@2|Bacteria,4NQQ9@976|Bacteroidetes,2FTDQ@200643|Bacteroidia,22Z1W@171551|Porphyromonadaceae	976|Bacteroidetes	G	L-rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
TH3_k127_3224340_4	700598.Niako_3627	2.805e-133	433.0	COG0697@1|root,2Z7ID@2|Bacteria,4NEHB@976|Bacteroidetes,1IVNN@117747|Sphingobacteriia	976|Bacteroidetes	EG	L-rhamnose-proton symport protein (RhaT)	rhaT	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
TH3_k127_3224340_0	313628.LNTAR_22814	1.853e-301	951.0	COG1554@1|root,COG1554@2|Bacteria	2|Bacteria	G	hydrolase, family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hyd_65N_2,Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
TH3_k127_3224340_3	1454007.JAUG01000073_gene4094	2.053e-167	549.0	COG2247@1|root,COG2247@2|Bacteria,4P17J@976|Bacteroidetes	976|Bacteroidetes	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF5013
TH3_k127_3224340_7	1122605.KB893637_gene3257	1.284e-46	190.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes	976|Bacteroidetes	G	glycosyl hydrolase of	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
TH3_k127_3224340_2	1267534.KB906755_gene4821	2.387e-176	576.0	COG3345@1|root,COG3345@2|Bacteria,3Y44J@57723|Acidobacteria,2JIVW@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3224340_9	1499967.BAYZ01000095_gene4068	8.367e-18	96.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
TH3_k127_3224340_10	1303518.CCALI_02173	4.753e-10	70.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_3224340_6	411479.BACUNI_04071	3.572e-64	239.0	COG0383@1|root,COG0383@2|Bacteria,4NI6N@976|Bacteroidetes,2FQGF@200643|Bacteroidia,4ANYA@815|Bacteroidaceae	976|Bacteroidetes	G	COG COG0383 Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
TH3_k127_3239291_12	497964.CfE428DRAFT_0261	3.014e-60	213.0	COG0607@1|root,COG0607@2|Bacteria,46VE6@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TH3_k127_3239291_14	497964.CfE428DRAFT_0260	1.448e-56	201.0	COG0822@1|root,COG0822@2|Bacteria,46VAC@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NifU-like N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
TH3_k127_3239291_2	497964.CfE428DRAFT_5386	1.46e-128	420.0	COG2876@1|root,COG2876@2|Bacteria,46SUJ@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
TH3_k127_3239291_3	478741.JAFS01000002_gene596	6.893e-122	404.0	COG4992@1|root,COG4992@2|Bacteria,46SUV@74201|Verrucomicrobia,37G7B@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TH3_k127_3239291_4	497964.CfE428DRAFT_0845	1.06e-119	391.0	COG0078@1|root,COG0078@2|Bacteria,46SA5@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
TH3_k127_3239291_23	1121116.KB894765_gene643	0.000426	53.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,4AAY1@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
TH3_k127_3239291_18	324602.Caur_0299	3.459e-15	89.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
TH3_k127_3239291_10	1157708.KB907454_gene2941	1.314e-68	256.0	COG4447@1|root,COG4886@1|root,COG4447@2|Bacteria,COG4886@2|Bacteria,1PIDF@1224|Proteobacteria,2WBU7@28216|Betaproteobacteria,4AIC2@80864|Comamonadaceae	28216|Betaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3239291_21	1396141.BATP01000023_gene664	4.698e-07	62.0	COG2931@1|root,COG3266@1|root,COG4733@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB,DUF1499,Flg_new
TH3_k127_3239291_15	635013.TherJR_0182	2.142e-48	182.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,2613S@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM MazG family protein	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
TH3_k127_3239291_8	452637.Oter_4153	2.165e-94	321.0	COG0263@1|root,COG0263@2|Bacteria,46SWM@74201|Verrucomicrobia,3K78E@414999|Opitutae	414999|Opitutae	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
TH3_k127_3239291_7	1121930.AQXG01000003_gene2719	5.616e-103	347.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
TH3_k127_3239291_11	272134.KB731324_gene6611	1.17e-66	258.0	COG0823@1|root,COG2373@1|root,COG2931@1|root,COG0823@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria,1HI2W@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domains in Na-Ca exchangers and integrin-beta4	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
TH3_k127_3239291_19	1303518.CCALI_02394	5.763e-10	70.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_3239291_20	326427.Cagg_1390	5.4e-09	63.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi,376QF@32061|Chloroflexia	32061|Chloroflexia	G	PFAM peptidase M18 aminopeptidase I	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
TH3_k127_3239291_0	595460.RRSWK_04532	1.15e-186	591.0	COG0673@1|root,COG0673@2|Bacteria,2IXPT@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_3239291_1	661478.OP10G_3858	2.971e-136	443.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	yrbE	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_3239291_5	497964.CfE428DRAFT_3531	5.097e-114	378.0	COG1044@1|root,COG1044@2|Bacteria,46SAD@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
TH3_k127_3239291_6	497964.CfE428DRAFT_0769	1.029e-107	368.0	COG1520@1|root,COG1520@2|Bacteria,46UNX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_3239291_9	1499967.BAYZ01000159_gene538	1.355e-69	251.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
TH3_k127_3239291_13	314230.DSM3645_26039	5.372e-59	225.0	COG4409@1|root,COG4409@2|Bacteria,2IX8T@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
TH3_k127_3239291_16	509635.N824_16950	5.455e-30	130.0	28MSZ@1|root,2ZB1A@2|Bacteria,4NHVN@976|Bacteroidetes	976|Bacteroidetes	S	GxGYxY sequence motif in domain of unknown function N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	GxGYxYP_C,GxGYxYP_N
TH3_k127_3349210_1	58123.JOFJ01000024_gene3453	0.0003818	53.0	COG1277@1|root,COG1277@2|Bacteria,2IIXQ@201174|Actinobacteria	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
TH3_k127_3349210_0	1123508.JH636439_gene1556	7.789e-75	259.0	COG1131@1|root,COG1131@2|Bacteria,2IXFI@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_3361702_9	1463936.JOJI01000044_gene7868	1.763e-38	156.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the carbohydrate kinase PfkB family	fruK	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
TH3_k127_3361702_6	886293.Sinac_7011	3.371e-98	348.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG2755@1|root,COG3794@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,COG3794@2|Bacteria,2IX6X@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,Cytochrome_CBB3,F5_F8_type_C,HEAT_2,Lipase_GDSL_2
TH3_k127_3361702_7	935845.JADQ01000029_gene1230	2.509e-91	344.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
TH3_k127_3361702_10	870187.Thini_0809	1.535e-09	73.0	COG1404@1|root,COG4932@1|root,COG1404@2|Bacteria,COG4932@2|Bacteria,1MU3S@1224|Proteobacteria,1RSP9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PKD,P_proprotein,Peptidase_S8
TH3_k127_3361702_11	498211.CJA_2236	2.744e-09	61.0	COG1396@1|root,COG1396@2|Bacteria,1R0M5@1224|Proteobacteria,1TBAA@1236|Gammaproteobacteria,1FHSR@10|Cellvibrio	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
TH3_k127_3361702_0	240016.ABIZ01000001_gene4136	0.0	1143.0	COG2010@1|root,COG3241@1|root,COG2010@2|Bacteria,COG3241@2|Bacteria	2|Bacteria	C	Transfers electrons from cytochrome c551 to cytochrome oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,F5_F8_type_C,HEAT_2,Lipase_GDSL_2
TH3_k127_3361702_8	497964.CfE428DRAFT_0022	1.551e-80	275.0	COG0217@1|root,COG0217@2|Bacteria,46SMV@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
TH3_k127_3361702_2	314230.DSM3645_20627	3.248e-142	466.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_3361702_3	314230.DSM3645_26739	7.405e-141	457.0	COG0329@1|root,COG0329@2|Bacteria,2IXEF@203682|Planctomycetes	203682|Planctomycetes	EM	Belongs to the DapA family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
TH3_k127_3361702_5	314230.DSM3645_26734	3.34e-106	355.0	COG0451@1|root,COG0451@2|Bacteria,2IXGI@203682|Planctomycetes	203682|Planctomycetes	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TH3_k127_3361702_1	497964.CfE428DRAFT_4707	5.116e-159	509.0	COG1060@1|root,COG1060@2|Bacteria	2|Bacteria	H	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity	mqnC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188	1.21.98.1,2.5.1.77	ko:K11779,ko:K11780,ko:K11781,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
TH3_k127_3361702_4	28072.Nos7524_5484	1.125e-116	401.0	COG2304@1|root,COG3209@1|root,COG3210@1|root,COG3266@1|root,COG5276@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3266@2|Bacteria,COG5276@2|Bacteria,1G4UG@1117|Cyanobacteria	1117|Cyanobacteria	M	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat
TH3_k127_3410570_9	1279009.ADICEAN_03353	6.388e-78	287.0	COG4547@1|root,COG4932@1|root,COG5644@1|root,COG4547@2|Bacteria,COG4932@2|Bacteria,COG5644@2|Bacteria,4PKCH@976|Bacteroidetes	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SdrD_B
TH3_k127_3410570_2	760192.Halhy_1406	7.925e-145	471.0	COG0673@1|root,COG0673@2|Bacteria,4NENY@976|Bacteroidetes	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_3410570_16	926569.ANT_03070	1.897e-26	128.0	COG5295@1|root,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi	200795|Chloroflexi	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3410570_18	324602.Caur_0299	3.561e-22	114.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
TH3_k127_3410570_14	111781.Lepto7376_0105	1.319e-38	168.0	COG1520@1|root,COG3210@1|root,COG3595@1|root,COG4995@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3595@2|Bacteria,COG4995@2|Bacteria,1G08N@1117|Cyanobacteria,1H96Q@1150|Oscillatoriales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act,P_proprotein
TH3_k127_3410570_15	195250.CM001776_gene2903	8.325e-28	132.0	COG0729@1|root,COG0729@2|Bacteria,1GDRV@1117|Cyanobacteria	1117|Cyanobacteria	M	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3410570_17	1297742.A176_05728	6.036e-25	112.0	COG5295@1|root,COG5295@2|Bacteria,1NI1M@1224|Proteobacteria,42ZTF@68525|delta/epsilon subdivisions,2WV01@28221|Deltaproteobacteria,2Z2QM@29|Myxococcales	28221|Deltaproteobacteria	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
TH3_k127_3410570_7	926569.ANT_30710	1.17e-87	300.0	COG1957@1|root,COG1957@2|Bacteria,2G7IF@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Inosine uridine-preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
TH3_k127_3410570_13	247490.KSU1_A0074	4.481e-41	156.0	COG0664@1|root,COG0664@2|Bacteria,2J0N9@203682|Planctomycetes	203682|Planctomycetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
TH3_k127_3410570_4	452637.Oter_4074	1.407e-112	373.0	COG2169@1|root,COG4936@1|root,COG2169@2|Bacteria,COG4936@2|Bacteria,46UZR@74201|Verrucomicrobia,3K795@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PocR
TH3_k127_3410570_6	309807.SRU_0678	1.773e-105	355.0	COG3829@1|root,COG4585@1|root,COG3829@2|Bacteria,COG4585@2|Bacteria,4PI8P@976|Bacteroidetes,1FIMB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS
TH3_k127_3410570_8	452637.Oter_1551	1.637e-78	269.0	COG2197@1|root,COG2197@2|Bacteria,46SRM@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_3410570_11	313628.LNTAR_08349	2.601e-54	203.0	COG0472@1|root,COG0472@2|Bacteria	313628.LNTAR_08349|-	M	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3410570_5	756272.Plabr_1226	1.386e-110	369.0	COG0438@1|root,COG0438@2|Bacteria,2IXN1@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TH3_k127_3410570_19	1122212.AULO01000008_gene1383	9.654e-06	59.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1XI7D@135619|Oceanospirillales	135619|Oceanospirillales	H	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_6,TPR_8
TH3_k127_3410570_10	479434.Sthe_2682	1.035e-71	256.0	COG2265@1|root,COG2265@2|Bacteria,2G6IV@200795|Chloroflexi,27XG5@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
TH3_k127_3410570_1	314230.DSM3645_06639	0.0	1189.0	COG2609@1|root,COG2609@2|Bacteria,2IXXY@203682|Planctomycetes	203682|Planctomycetes	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
TH3_k127_3410570_3	452637.Oter_2746	1.366e-131	438.0	COG1249@1|root,COG1249@2|Bacteria,46S8I@74201|Verrucomicrobia,3K7TS@414999|Opitutae	414999|Opitutae	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
TH3_k127_3410570_0	1396141.BATP01000024_gene849	0.0	1315.0	COG3696@1|root,COG3696@2|Bacteria,46SJ1@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
TH3_k127_343736_4	330214.NIDE3236	1.353e-177	565.0	COG1140@1|root,COG1140@2|Bacteria,3J1FU@40117|Nitrospirae	2|Bacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	ddhB	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.5.1	ko:K00371,ko:K16965,ko:K17048,ko:K17051	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8,5.A.3.9	-	-	Fer4_11
TH3_k127_343736_27	247490.KSU1_B0259	2.521e-24	117.0	COG3381@1|root,COG3381@2|Bacteria,2J3EZ@203682|Planctomycetes	203682|Planctomycetes	S	Nitrate reductase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
TH3_k127_343736_25	237368.SCABRO_01075	5.125e-32	137.0	2AKTZ@1|root,31BM1@2|Bacteria,2J2UU@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_343736_30	452637.Oter_3126	2.16e-19	91.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
TH3_k127_343736_15	290397.Adeh_3087	1.349e-85	292.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42QZ2@68525|delta/epsilon subdivisions,2WMS4@28221|Deltaproteobacteria,2Z16M@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	cbcT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_2,Fer4_3,Fer4_7
TH3_k127_343736_10	1379698.RBG1_1C00001G0297	8.387e-124	409.0	COG4881@1|root,COG4881@2|Bacteria	2|Bacteria	-	-	cbcU	-	-	-	-	-	-	-	-	-	-	-	NrfD
TH3_k127_343736_29	1121920.AUAU01000009_gene1858	3.049e-22	105.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
TH3_k127_343736_12	1125863.JAFN01000001_gene561	1.411e-109	364.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,43AKQ@68525|delta/epsilon subdivisions,2X60P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
TH3_k127_343736_9	1396141.BATP01000019_gene1673	1.064e-127	428.0	COG5557@1|root,COG5557@2|Bacteria,46U15@74201|Verrucomicrobia,2ITS8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
TH3_k127_343736_31	452637.Oter_3126	6.819e-18	90.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
TH3_k127_343736_7	452637.Oter_2584	1.833e-154	502.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
TH3_k127_343736_1	1121920.AUAU01000001_gene2269	6.878e-308	957.0	COG2864@1|root,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	2|Bacteria	C	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
TH3_k127_343736_3	903818.KI912269_gene259	6.683e-185	597.0	COG2864@1|root,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	57723|Acidobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
TH3_k127_343736_33	452637.Oter_3675	1.316e-13	74.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hdrC	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389,ko:K03390,ko:K16887,ko:K18930	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3424	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8,Fer4_9
TH3_k127_343736_8	316067.Geob_1632	9.244e-140	471.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MRH@68525|delta/epsilon subdivisions,2WM8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
TH3_k127_343736_19	644282.Deba_1749	4.349e-58	216.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43C2A@68525|delta/epsilon subdivisions,2X7CW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
TH3_k127_343736_32	1499967.BAYZ01000059_gene4768	9.615e-16	83.0	COG0745@1|root,COG0745@2|Bacteria	1499967.BAYZ01000059_gene4768|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_343736_26	880073.Calab_3048	2.929e-30	132.0	COG1150@1|root,COG1150@2|Bacteria,2NQ2K@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hdrC	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389,ko:K03390,ko:K16887,ko:K18930	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3424	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8,Fer4_9
TH3_k127_343736_17	1379698.RBG1_1C00001G0051	7.247e-73	260.0	COG2048@1|root,COG2048@2|Bacteria,2NQP7@2323|unclassified Bacteria	2|Bacteria	C	Heterodisulfide reductase subunit B	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
TH3_k127_343736_20	562970.Btus_2493	1.681e-52	194.0	COG2086@1|root,COG2086@2|Bacteria,1VUFC@1239|Firmicutes	1239|Firmicutes	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
TH3_k127_343736_16	525909.Afer_0970	3.258e-78	272.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4CNP3@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
TH3_k127_343736_5	1238450.VIBNISOn1_970135	8.441e-164	537.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,1XSGD@135623|Vibrionales	135623|Vibrionales	C	Cysteine-rich domain	-	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
TH3_k127_343736_11	309801.trd_0150	2.176e-113	378.0	COG0247@1|root,COG0247@2|Bacteria,2G5X6@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG
TH3_k127_343736_0	452637.Oter_3677	9.531e-318	985.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
TH3_k127_343736_18	880073.Calab_3045	2.741e-60	213.0	COG1908@1|root,COG1908@2|Bacteria,2NPFI@2323|unclassified Bacteria	2|Bacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	bamF	-	1.8.98.5,1.8.98.6	ko:K14127,ko:K14128	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2083	Fer4,FlpD,HTH_5
TH3_k127_343736_6	452637.Oter_3679	6.525e-155	498.0	COG1941@1|root,COG1941@2|Bacteria,46T7U@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	frhG	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
TH3_k127_343736_2	452637.Oter_3680	3.013e-255	799.0	COG3259@1|root,COG3259@2|Bacteria,46STG@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Nickel-dependent hydrogenase	frhA	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
TH3_k127_343736_23	452637.Oter_3681	4.013e-33	135.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	hycI	GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.23.51	ko:K00442,ko:K03605,ko:K04656,ko:K08315	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_3329	HycI
TH3_k127_343736_24	497964.CfE428DRAFT_0900	3.111e-32	134.0	2C6YV@1|root,3392Q@2|Bacteria,46T7D@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_343736_14	452637.Oter_3509	8.451e-89	310.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_343736_21	314230.DSM3645_14090	1.018e-51	206.0	COG1413@1|root,COG3828@1|root,COG1413@2|Bacteria,COG3828@2|Bacteria,2IX8S@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_343736_22	1408473.JHXO01000006_gene1364	5.451e-47	191.0	COG1082@1|root,COG1082@2|Bacteria,4NJJZ@976|Bacteroidetes,2FQWU@200643|Bacteroidia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_343736_28	234267.Acid_0845	7.232e-23	108.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	cpeZ	-	-	ko:K05384,ko:K05386	ko00196,ko01100,map00196,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	HEAT_2
TH3_k127_3448565_5	1121403.AUCV01000014_gene4604	0.0003039	45.0	COG3420@1|root,COG3420@2|Bacteria,1NIRV@1224|Proteobacteria	1224|Proteobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TH3_k127_3448565_0	1077285.AGDG01000045_gene2975	1.118e-263	847.0	COG0383@1|root,COG0383@2|Bacteria,4NI6N@976|Bacteroidetes,2FQGF@200643|Bacteroidia,4ANYA@815|Bacteroidaceae	976|Bacteroidetes	G	COG COG0383 Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
TH3_k127_3448565_4	1121381.JNIV01000032_gene2525	2.67e-09	71.0	COG3055@1|root,COG3250@1|root,COG3055@2|Bacteria,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060,Kelch_1,Kelch_6,NPCBM,SpoIIE
TH3_k127_3448565_1	1211813.CAPH01000001_gene1170	9.185e-126	434.0	COG3345@1|root,COG3345@2|Bacteria,4NZUR@976|Bacteroidetes,2FNUD@200643|Bacteroidia	976|Bacteroidetes	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
TH3_k127_3448565_2	314230.DSM3645_20877	2.36e-85	292.0	COG1506@1|root,COG2755@1|root,COG1506@2|Bacteria,COG2755@2|Bacteria,2J4YR@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TH3_k127_3448565_3	349741.Amuc_2166	3.007e-14	74.0	COG0673@1|root,COG0673@2|Bacteria,46W0X@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_3540481_1	143224.JQMD01000002_gene1290	6.069e-69	262.0	COG3386@1|root,COG3386@2|Bacteria,4NGVD@976|Bacteroidetes,1I0H5@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
TH3_k127_3540481_0	251229.Chro_2571	2.558e-170	563.0	COG2730@1|root,COG2730@2|Bacteria,1GRHI@1117|Cyanobacteria,3VM2P@52604|Pleurocapsales	1117|Cyanobacteria	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
TH3_k127_3540481_3	471852.Tcur_1015	1.755e-11	76.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4ER4V@85012|Streptosporangiales	201174|Actinobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Malectin,PKD
TH3_k127_3540481_2	234267.Acid_6525	8.958e-29	131.0	COG5512@1|root,COG5512@2|Bacteria,3Y2P3@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
TH3_k127_3567542_16	1121035.AUCH01000017_gene2319	1.468e-30	131.0	COG0707@1|root,COG0707@2|Bacteria,1QU89@1224|Proteobacteria,2VKVF@28216|Betaproteobacteria,2KX6K@206389|Rhodocyclales	206389|Rhodocyclales	M	Monogalactosyldiacylglycerol (MGDG) synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,MGDG_synth
TH3_k127_3567542_1	886293.Sinac_0656	1.122e-240	757.0	COG1053@1|root,COG1053@2|Bacteria,2IYNS@203682|Planctomycetes	203682|Planctomycetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
TH3_k127_3567542_18	977880.RALTA_A2916	2.352e-22	100.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,1KHET@119060|Burkholderiaceae	28216|Betaproteobacteria	P	tolerance protein	cutA	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
TH3_k127_3567542_15	215803.DB30_3302	2.678e-38	151.0	2F6YT@1|root,33ZET@2|Bacteria,1Q2TV@1224|Proteobacteria,438FU@68525|delta/epsilon subdivisions,2X3QS@28221|Deltaproteobacteria,2YWVH@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3567542_0	497964.CfE428DRAFT_1508	6.895e-242	759.0	COG1620@1|root,COG1620@2|Bacteria,46UQW@74201|Verrucomicrobia	74201|Verrucomicrobia	C	L-lactate permease	-	-	-	-	-	-	-	-	-	-	-	-	Lactate_perm
TH3_k127_3567542_22	357808.RoseRS_4349	1.515e-13	78.0	COG1247@1|root,COG1247@2|Bacteria,2G9YI@200795|Chloroflexi,377A3@32061|Chloroflexia	32061|Chloroflexia	M	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TH3_k127_3567542_19	1396418.BATQ01000058_gene110	4.757e-21	95.0	2EMGZ@1|root,33F5K@2|Bacteria,46TB4@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3567542_6	1210884.HG799472_gene14911	2.628e-115	384.0	COG1520@1|root,COG1520@2|Bacteria,2IWXJ@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_3567542_5	452637.Oter_1003	1.956e-135	443.0	COG4299@1|root,COG4299@2|Bacteria,46S60@74201|Verrucomicrobia	74201|Verrucomicrobia	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
TH3_k127_3567542_2	497964.CfE428DRAFT_4132	2.866e-177	567.0	COG1520@1|root,COG1520@2|Bacteria,46UCM@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_3567542_8	497964.CfE428DRAFT_2876	7.003e-90	301.0	COG2818@1|root,COG2818@2|Bacteria,46SS9@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
TH3_k127_3567542_7	886293.Sinac_5304	6.803e-108	370.0	COG0477@1|root,COG2814@2|Bacteria,2IY3A@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
TH3_k127_3567542_17	1156937.MFUM_1030013	1.676e-30	127.0	COG0203@1|root,COG0203@2|Bacteria,46TC9@74201|Verrucomicrobia,37GVV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
TH3_k127_3567542_4	1396141.BATP01000018_gene1517	2.303e-146	470.0	COG0202@1|root,COG0202@2|Bacteria,46S52@74201|Verrucomicrobia,2ITN6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
TH3_k127_3567542_10	278957.ABEA03000041_gene2061	1.713e-77	265.0	COG0522@1|root,COG0522@2|Bacteria,46SNI@74201|Verrucomicrobia,3K7K0@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
TH3_k127_3567542_12	497964.CfE428DRAFT_0509	2.446e-55	199.0	COG0100@1|root,COG0100@2|Bacteria,46STW@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
TH3_k127_3567542_13	497964.CfE428DRAFT_0508	1.171e-50	182.0	COG0099@1|root,COG0099@2|Bacteria,46STA@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
TH3_k127_3567542_23	754252.PFREUD_06030	3.528e-12	67.0	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
TH3_k127_3567542_20	1410670.JHXF01000006_gene1255	1.959e-16	81.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,3WK1D@541000|Ruminococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
TH3_k127_3567542_9	497964.CfE428DRAFT_0506	4.038e-84	286.0	COG0024@1|root,COG0024@2|Bacteria,46SK6@74201|Verrucomicrobia	74201|Verrucomicrobia	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
TH3_k127_3567542_3	452637.Oter_0207	2.821e-151	491.0	COG0201@1|root,COG0201@2|Bacteria,46S86@74201|Verrucomicrobia,3K7NJ@414999|Opitutae	414999|Opitutae	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
TH3_k127_3567542_14	497964.CfE428DRAFT_0504	7.383e-49	179.0	COG0200@1|root,COG0200@2|Bacteria,46SSX@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
TH3_k127_3567542_11	497964.CfE428DRAFT_0503	5.038e-57	205.0	COG0098@1|root,COG0098@2|Bacteria,46SUR@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
TH3_k127_3567542_21	771875.Ferpe_1400	1.476e-13	73.0	COG0256@1|root,COG0256@2|Bacteria,2GD32@200918|Thermotogae	200918|Thermotogae	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
TH3_k127_3612728_0	83332.Rv0663	0.0	1142.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,233CA@1762|Mycobacteriaceae	201174|Actinobacteria	P	thought to play an important role in the mineralization of sulfates catalytic activity a phenol sulfate H2O a phenol sulfate	atsD	GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008484,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043167,GO:0043169,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097708,GO:0099503,GO:1901135,GO:1901564,GO:1903509	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
TH3_k127_3612728_6	1268068.PG5_33320	4.945e-107	362.0	COG2067@1|root,COG2067@2|Bacteria,1R3SS@1224|Proteobacteria,1S0X2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
TH3_k127_3612728_13	525897.Dbac_1089	6.626e-55	199.0	2E9FY@1|root,333P7@2|Bacteria,1N8S6@1224|Proteobacteria,42XWP@68525|delta/epsilon subdivisions,2WSIE@28221|Deltaproteobacteria,2MFM6@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3612728_10	575540.Isop_2535	4.759e-75	262.0	COG0580@1|root,COG0580@2|Bacteria,2IZDN@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
TH3_k127_3612728_19	522306.CAP2UW1_1267	1.6e-18	93.0	2EBP0@1|root,335P6@2|Bacteria,1N33Y@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3612728_3	1123242.JH636436_gene23	1.339e-153	501.0	COG1335@1|root,COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1335@2|Bacteria,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TH3_k127_3612728_15	761193.Runsl_2772	2.366e-49	188.0	COG0329@1|root,COG0329@2|Bacteria,4NI1I@976|Bacteroidetes,47NMJ@768503|Cytophagia	976|Bacteroidetes	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
TH3_k127_3612728_12	234267.Acid_5864	2.582e-57	213.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_3612728_11	583355.Caka_0200	3.24e-69	249.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6
TH3_k127_3612728_1	1123278.KB893563_gene4551	2.073e-255	811.0	COG3507@1|root,COG3507@2|Bacteria,4NEVJ@976|Bacteroidetes,47JBZ@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,CBM_6,Glyco_hydro_43
TH3_k127_3612728_7	661478.OP10G_2561	1.972e-95	342.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
TH3_k127_3612728_9	926566.Terro_1270	2.223e-83	292.0	COG3693@1|root,COG3693@2|Bacteria,3Y6EW@57723|Acidobacteria	57723|Acidobacteria	G	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_10
TH3_k127_3612728_5	1396141.BATP01000001_gene5356	1.79e-142	464.0	COG2382@1|root,COG2382@2|Bacteria,46YZE@74201|Verrucomicrobia,2IU0Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
TH3_k127_3612728_4	1346791.M529_08415	1.923e-152	492.0	COG2382@1|root,COG2382@2|Bacteria,1QU4Q@1224|Proteobacteria,2UCAB@28211|Alphaproteobacteria,2K2IZ@204457|Sphingomonadales	204457|Sphingomonadales	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
TH3_k127_3612728_2	714943.Mucpa_3835	1.211e-202	666.0	COG3534@1|root,COG3534@2|Bacteria,4NH8M@976|Bacteroidetes,1IVFD@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C
TH3_k127_3612728_17	1173026.Glo7428_2145	4.002e-29	136.0	COG2730@1|root,COG2730@2|Bacteria,1G7EB@1117|Cyanobacteria	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
TH3_k127_3612728_18	234267.Acid_2103	6.427e-22	98.0	COG2382@1|root,COG2382@2|Bacteria,3Y2ZN@57723|Acidobacteria	2|Bacteria	GP	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,Glyco_hydro_10
TH3_k127_3612728_20	1462527.CCDM010000004_gene3638	2.114e-06	51.0	2EJBT@1|root,33D2X@2|Bacteria,1VKP4@1239|Firmicutes,4HRCQ@91061|Bacilli,23N7H@182709|Oceanobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3612728_14	926550.CLDAP_00200	1.762e-54	202.0	COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi	200795|Chloroflexi	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
TH3_k127_3612728_16	644801.Psest_3899	1.394e-42	163.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,1S3SH@1236|Gammaproteobacteria,1Z115@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	phosphoribosyltransferases	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
TH3_k127_3612728_8	639282.DEFDS_0119	2.285e-94	317.0	COG0528@1|root,COG0528@2|Bacteria,2GEZE@200930|Deferribacteres	200930|Deferribacteres	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
TH3_k127_3624585_0	1123508.JH636445_gene6496	1.499e-156	520.0	COG5337@1|root,COG5337@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
TH3_k127_3624585_1	1122176.KB903609_gene5148	1.205e-113	394.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
TH3_k127_3624585_6	237368.SCABRO_02994	3.223e-27	121.0	COG2930@1|root,COG2930@2|Bacteria,2IZZF@203682|Planctomycetes	203682|Planctomycetes	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
TH3_k127_3624585_2	1156937.MFUM_1020047	3.787e-85	301.0	COG4591@1|root,COG4591@2|Bacteria,46SKZ@74201|Verrucomicrobia,37G6B@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	MacB-like periplasmic core domain	lolE	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
TH3_k127_3624585_3	598467.BrE312_1653	3.236e-68	238.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
TH3_k127_3624585_4	497964.CfE428DRAFT_3025	1.647e-43	168.0	COG0500@1|root,COG0500@2|Bacteria,46SYP@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	TPMT
TH3_k127_3624585_5	195250.CM001776_gene2551	1.02e-32	145.0	COG2931@1|root,COG3209@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,RHS_repeat,VCBS
TH3_k127_3636427_4	589865.DaAHT2_1111	1.263e-110	363.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MIWX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
TH3_k127_3636427_1	589865.DaAHT2_1112	1.8e-256	806.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
TH3_k127_3636427_6	344747.PM8797T_28884	6.211e-59	216.0	COG0731@1|root,COG0731@2|Bacteria,2IXA2@203682|Planctomycetes	203682|Planctomycetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TH3_k127_3636427_5	452637.Oter_0906	4.253e-74	266.0	COG0664@1|root,COG0664@2|Bacteria,46VK1@74201|Verrucomicrobia,3K7W4@414999|Opitutae	74201|Verrucomicrobia	K	Crp Fnr family	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TH3_k127_3636427_3	1379698.RBG1_1C00001G0011	2.35e-125	419.0	COG2010@1|root,COG2180@1|root,COG2010@2|Bacteria,COG2180@2|Bacteria,2NR8D@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c	narJ	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	-	ko:K00373,ko:K00405,ko:K17052	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko02000	3.D.4.3,5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687	Nitrate_red_del
TH3_k127_3636427_0	247490.KSU1_D0577	0.0	1563.0	COG0243@1|root,COG0243@2|Bacteria,2J2QN@203682|Planctomycetes	203682|Planctomycetes	C	Molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin
TH3_k127_3636427_7	1131269.AQVV01000004_gene610	8.333e-05	51.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	-	-	5.2.1.8	ko:K01802,ko:K03770,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
TH3_k127_3636427_2	330214.NIDE3236	3.445e-175	559.0	COG1140@1|root,COG1140@2|Bacteria,3J1FU@40117|Nitrospirae	2|Bacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	ddhB	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.5.1	ko:K00371,ko:K16965,ko:K17048,ko:K17051	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8,5.A.3.9	-	-	Fer4_11
TH3_k127_3701813_0	221288.JH992901_gene3910	0.0	1767.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JJIN@1189|Stigonemataceae	1117|Cyanobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,TauD,Thioesterase
TH3_k127_3705772_0	330214.NIDE3608	1.422e-58	221.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874,Glyco_hydro_42
TH3_k127_3705772_1	1195236.CTER_0486	6.024e-18	98.0	COG2133@1|root,COG2182@1|root,COG3507@1|root,COG3669@1|root,COG3979@1|root,COG2133@2|Bacteria,COG2182@2|Bacteria,COG3507@2|Bacteria,COG3669@2|Bacteria,COG3979@2|Bacteria,1VRJN@1239|Firmicutes,24DFN@186801|Clostridia,3WIA2@541000|Ruminococcaceae	186801|Clostridia	G	PA14	-	-	-	-	-	-	-	-	-	-	-	-	PA14,RsgI_N
TH3_k127_3730481_3	762984.HMPREF9445_02056	6.267e-06	57.0	COG5652@1|root,COG5652@2|Bacteria,4NIE7@976|Bacteroidetes,2FQJV@200643|Bacteroidia,4AQA0@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4962)	-	GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008201,GO:0009056,GO:0009057,GO:0009987,GO:0016829,GO:0016835,GO:0016837,GO:0030202,GO:0030203,GO:0030211,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044464,GO:0047488,GO:0071704,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901681,GO:1903510	4.2.2.7,4.2.2.8	ko:K19051	-	-	-	-	ko00000,ko01000	-	PL21	-	DUF4962,Hepar_II_III
TH3_k127_3730481_4	1089548.KI783301_gene1779	0.0003716	54.0	COG3055@1|root,COG4412@1|root,COG5184@1|root,COG3055@2|Bacteria,COG4412@2|Bacteria,COG5184@2|Bacteria,1VW0A@1239|Firmicutes,4HWE6@91061|Bacilli,3WFP4@539002|Bacillales incertae sedis	2|Bacteria	DZ	S-layer homology domain	-	-	3.2.1.18,3.2.1.52,3.2.1.8	ko:K01181,ko:K01186,ko:K12373,ko:K20276	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko02024,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map02024,map04142	M00079	R00022,R04018,R06004,R11316	RC00028,RC00049,RC00077	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	-	GH20,GH33	-	DUF1929,DUF4347,F5_F8_type_C,FIVAR,He_PIG,HemolysinCabind,Kelch_1,Kelch_4,Laminin_G_3,SLH
TH3_k127_3730481_5	251229.Chro_0789	0.0004119	48.0	COG3420@1|root,COG3420@2|Bacteria,1GPUW@1117|Cyanobacteria,3VJI4@52604|Pleurocapsales	1117|Cyanobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TH3_k127_3730481_2	620914.JH621310_gene55	4.708e-20	104.0	COG2273@1|root,COG5434@1|root,COG2273@2|Bacteria,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_6,Glyco_hydro_16,Pectate_lyase_3,RicinB_lectin_2
TH3_k127_3730481_0	497964.CfE428DRAFT_4394	5.727e-213	668.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos,Beta_helix,F5_F8_type_C,Glyco_hydro_28,Melibiase_2,Pectate_lyase_3
TH3_k127_3730481_1	1449063.JMLS01000009_gene2209	5.558e-135	456.0	28H6M@1|root,2Z7J0@2|Bacteria	2|Bacteria	G	Pectate lyase	pelY	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Pectate_lyase_2
TH3_k127_3738090_10	647113.Metok_0016	3.285e-63	233.0	COG0668@1|root,arCOG01568@2157|Archaea,2XSU5@28890|Euryarchaeota,23QB0@183939|Methanococci	183939|Methanococci	M	PFAM MscS Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
TH3_k127_3738090_3	497964.CfE428DRAFT_3481	9.365e-209	673.0	COG0443@1|root,COG0443@2|Bacteria,46TYN@74201|Verrucomicrobia	74201|Verrucomicrobia	O	MreB/Mbl protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
TH3_k127_3738090_9	452637.Oter_0619	1.482e-66	239.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	VVA1313	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TH3_k127_3738090_12	481448.Minf_1524	2.122e-34	141.0	COG0452@1|root,COG0452@2|Bacteria,46WUX@74201|Verrucomicrobia,37GRH@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	DNA / pantothenate metabolism flavoprotein	-	-	6.3.2.5	ko:K21977	ko00770,map00770	M00120	R04231	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP
TH3_k127_3738090_6	278957.ABEA03000085_gene2554	1.052e-108	359.0	COG0583@1|root,COG0583@2|Bacteria,46SCJ@74201|Verrucomicrobia,3K7FY@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TH3_k127_3738090_11	335543.Sfum_2639	2.015e-59	227.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WKMP@28221|Deltaproteobacteria,2MQVW@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
TH3_k127_3738090_13	880073.Calab_0824	6.553e-29	123.0	COG0295@1|root,COG0295@2|Bacteria,2NPJN@2323|unclassified Bacteria	2|Bacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	GO:0001882,GO:0001884,GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006217,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009116,GO:0009119,GO:0009120,GO:0009164,GO:0009972,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0036094,GO:0042454,GO:0042802,GO:0043094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046092,GO:0046121,GO:0046125,GO:0046127,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	iECO103_1326.ECO103_2618	dCMP_cyt_deam_1,dCMP_cyt_deam_2
TH3_k127_3738090_8	1382315.JPOI01000001_gene1963	3.825e-71	253.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1WE42@129337|Geobacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
TH3_k127_3738090_14	497964.CfE428DRAFT_5353	1.038e-27	127.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
TH3_k127_3738090_16	1123248.KB893324_gene1755	6.637e-15	87.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1IPM8@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TH3_k127_3738090_15	471223.GWCH70_1512	3.284e-21	100.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,1WEX0@129337|Geobacillus	91061|Bacilli	G	PTS system, Lactose/Cellobiose specific IIB subunit	fruA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
TH3_k127_3738090_18	1273125.Rrhod_2956	0.0003437	49.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4FUXM@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the UPF0232 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
TH3_k127_3738090_5	935948.KE386494_gene695	9.37e-147	489.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,42FYE@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Glycoside hydrolase family 42 domain protein	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
TH3_k127_3738090_17	1123242.JH636435_gene2068	1.813e-12	80.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
TH3_k127_3738090_4	497964.CfE428DRAFT_5737	6.06e-200	630.0	COG0673@1|root,COG0673@2|Bacteria,46UQI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_3738090_1	1396418.BATQ01000117_gene4568	2.169e-231	727.0	COG0738@1|root,COG0738@2|Bacteria,46U7F@74201|Verrucomicrobia,2IUMJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TH3_k127_3738090_0	497964.CfE428DRAFT_0141	0.0	1083.0	COG1082@1|root,COG4993@1|root,COG1082@2|Bacteria,COG4993@2|Bacteria,46T43@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ
TH3_k127_3738090_7	530564.Psta_0173	2.164e-95	329.0	COG0501@1|root,COG3170@1|root,COG0501@2|Bacteria,COG3170@2|Bacteria,2IXM0@203682|Planctomycetes	203682|Planctomycetes	O	Zn-dependent protease with chaperone function	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TH3_k127_3738090_2	1403819.BATR01000157_gene5202	6.44e-216	714.0	COG0587@1|root,COG0587@2|Bacteria,46SG0@74201|Verrucomicrobia,2ITPP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase alpha chain like domain	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
TH3_k127_3739858_16	106582.XP_004571112.1	3.098e-24	117.0	KOG1215@1|root,KOG1215@2759|Eukaryota,38B6M@33154|Opisthokonta,3B9HR@33208|Metazoa,3CTYV@33213|Bilateria,47YVC@7711|Chordata,497BX@7742|Vertebrata,49TNF@7898|Actinopterygii	33208|Metazoa	T	lipoprotein receptor-related protein	LRP4	GO:0000902,GO:0000904,GO:0001655,GO:0001822,GO:0001932,GO:0001934,GO:0001941,GO:0001942,GO:0003002,GO:0003674,GO:0004888,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0007166,GO:0007267,GO:0007275,GO:0007389,GO:0007399,GO:0007416,GO:0007528,GO:0008104,GO:0008150,GO:0008544,GO:0009653,GO:0009790,GO:0009798,GO:0009887,GO:0009888,GO:0009893,GO:0009950,GO:0009953,GO:0009954,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0010562,GO:0010604,GO:0010646,GO:0010648,GO:0010721,GO:0010769,GO:0010771,GO:0010975,GO:0010977,GO:0014069,GO:0016020,GO:0016043,GO:0016055,GO:0016358,GO:0017147,GO:0019220,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022404,GO:0022405,GO:0022603,GO:0022604,GO:0022607,GO:0023051,GO:0023052,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030178,GO:0030182,GO:0030278,GO:0030279,GO:0030326,GO:0030424,GO:0030425,GO:0030971,GO:0031175,GO:0031323,GO:0031325,GO:0031344,GO:0031345,GO:0031399,GO:0031401,GO:0031594,GO:0032268,GO:0032270,GO:0032279,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033267,GO:0034185,GO:0034613,GO:0035107,GO:0035108,GO:0035113,GO:0036477,GO:0038023,GO:0040007,GO:0042303,GO:0042325,GO:0042327,GO:0042475,GO:0042476,GO:0042633,GO:0042733,GO:0042802,GO:0042803,GO:0042813,GO:0042995,GO:0043005,GO:0043025,GO:0043113,GO:0043226,GO:0043235,GO:0043588,GO:0043679,GO:0043933,GO:0044085,GO:0044091,GO:0044297,GO:0044306,GO:0044332,GO:0044425,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045202,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045937,GO:0046983,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048589,GO:0048598,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048736,GO:0048812,GO:0048813,GO:0048856,GO:0048858,GO:0048869,GO:0050730,GO:0050731,GO:0050767,GO:0050768,GO:0050770,GO:0050771,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050808,GO:0050896,GO:0051093,GO:0051124,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051262,GO:0051290,GO:0051291,GO:0051641,GO:0051668,GO:0051716,GO:0051960,GO:0051961,GO:0060070,GO:0060089,GO:0060173,GO:0060255,GO:0060284,GO:0060341,GO:0060429,GO:0060828,GO:0061024,GO:0065003,GO:0065007,GO:0065008,GO:0070727,GO:0071340,GO:0071709,GO:0071840,GO:0071944,GO:0072001,GO:0072657,GO:0080090,GO:0090090,GO:0097060,GO:0097090,GO:0097104,GO:0097105,GO:0097110,GO:0097447,GO:0097458,GO:0098590,GO:0098773,GO:0098793,GO:0098794,GO:0098984,GO:0099054,GO:0099068,GO:0099172,GO:0099173,GO:0099175,GO:0099572,GO:0120025,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0150034,GO:0198738,GO:1901626,GO:1901628,GO:1901629,GO:1901631,GO:1903827,GO:1903829,GO:1903909,GO:1903911,GO:1904393,GO:1904395,GO:1904396,GO:1904398,GO:1905114,GO:1905475,GO:1905477,GO:1990709,GO:1990782,GO:2000026	-	ko:K20051	-	-	-	-	ko00000,ko04131	-	-	-	EGF_CA,FXa_inhibition,Ldl_recept_a,Ldl_recept_b,cEGF
TH3_k127_3739858_15	880073.Calab_0118	2.321e-24	118.0	COG2911@1|root,COG4733@1|root,COG2911@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.89	ko:K01224,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DctA-YdbH,Laminin_G_3
TH3_k127_3739858_20	153721.MYP_4858	3.779e-13	80.0	COG4733@1|root,COG4733@2|Bacteria,4NTXR@976|Bacteroidetes,47SSC@768503|Cytophagia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
TH3_k127_3739858_0	478741.JAFS01000001_gene2217	3.516e-295	924.0	COG0507@1|root,COG0507@2|Bacteria,46USC@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Helix-hairpin-helix containing domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
TH3_k127_3739858_17	794903.OPIT5_04595	5.335e-22	99.0	COG1396@1|root,COG1396@2|Bacteria,46WYF@74201|Verrucomicrobia,3K9Q1@414999|Opitutae	414999|Opitutae	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
TH3_k127_3739858_14	497964.CfE428DRAFT_2383	9.873e-25	109.0	2F78F@1|root,33ZPQ@2|Bacteria,46VT2@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3739858_10	883126.HMPREF9710_02976	8.882e-48	175.0	COG1539@1|root,COG1539@2|Bacteria,1QVAP@1224|Proteobacteria,2WHHJ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
TH3_k127_3739858_19	383372.Rcas_3433	9.319e-15	84.0	COG0658@1|root,COG0658@2|Bacteria,2G6G7@200795|Chloroflexi,375B1@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ComEC Rec2-related protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
TH3_k127_3739858_18	903814.ELI_3081	1.987e-18	92.0	COG1408@1|root,COG5652@1|root,COG1408@2|Bacteria,COG5652@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,25X0Z@186806|Eubacteriaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
TH3_k127_3739858_6	497964.CfE428DRAFT_2062	2.791e-77	272.0	COG0854@1|root,COG0854@2|Bacteria,46SJT@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
TH3_k127_3739858_12	497964.CfE428DRAFT_2063	4.438e-35	137.0	COG0736@1|root,COG0736@2|Bacteria,46T5U@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
TH3_k127_3739858_3	497964.CfE428DRAFT_0539	5.094e-96	317.0	COG1403@1|root,COG1403@2|Bacteria,46SMP@74201|Verrucomicrobia	74201|Verrucomicrobia	L	HNH endonuclease	mcrA	-	-	-	-	-	-	-	-	-	-	-	HNH_5
TH3_k127_3739858_13	478741.JAFS01000001_gene1060	5.615e-27	114.0	COG2026@1|root,COG2026@2|Bacteria,46Z14@74201|Verrucomicrobia,37H0T@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	DJ	Addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3739858_7	1301098.PKB_0417	2.564e-63	221.0	COG2314@1|root,COG2314@2|Bacteria,1RHUU@1224|Proteobacteria,1S694@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	TM2
TH3_k127_3739858_1	1210884.HG799465_gene12146	1.494e-140	459.0	COG1520@1|root,COG1520@2|Bacteria,2J2YU@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_3739858_4	234267.Acid_2605	2.183e-87	296.0	COG2133@1|root,COG2133@2|Bacteria,3Y3FI@57723|Acidobacteria	57723|Acidobacteria	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_3739858_5	497964.CfE428DRAFT_0418	3.666e-86	297.0	COG1573@1|root,COG1573@2|Bacteria,46SSB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
TH3_k127_3739858_8	497964.CfE428DRAFT_5674	6.588e-50	186.0	COG0586@1|root,COG0586@2|Bacteria,46SWW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
TH3_k127_3739858_9	452637.Oter_0887	1.844e-49	196.0	COG4726@1|root,COG4726@2|Bacteria,46VER@74201|Verrucomicrobia,3K9MT@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3739858_21	497964.CfE428DRAFT_4822	4.909e-07	56.0	2B6YR@1|root,2ZVXX@2|Bacteria,46WP9@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3739858_11	497964.CfE428DRAFT_4818	1.924e-35	142.0	COG3436@1|root,COG3436@2|Bacteria,46VCT@74201|Verrucomicrobia	74201|Verrucomicrobia	L	IS66 Orf2 like protein	-	-	-	-	-	-	-	-	-	-	-	-	TnpB_IS66
TH3_k127_3739858_2	497964.CfE428DRAFT_4819	4.15e-138	453.0	COG2433@1|root,COG2433@2|Bacteria,46Z8U@74201|Verrucomicrobia	2|Bacteria	S	PFAM transposase IS66	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
TH3_k127_3741396_0	1396418.BATQ01000010_gene3751	7.03e-199	677.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
TH3_k127_3741396_1	497964.CfE428DRAFT_2982	6.862e-61	219.0	COG1595@1|root,COG1595@2|Bacteria,46V3P@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
TH3_k127_3741396_5	1521187.JPIM01000047_gene117	4.609e-09	59.0	COG3293@1|root,COG3293@2|Bacteria,2G7YC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
TH3_k127_3741396_3	1047013.AQSP01000122_gene2233	3.561e-13	82.0	COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
TH3_k127_3741396_4	378806.STAUR_1759	2.049e-09	64.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria	1224|Proteobacteria	G	Domain of unknown function (DUF4982)	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
TH3_k127_376724_3	702438.HMPREF9431_00108	1.445e-21	101.0	COG1569@1|root,COG1569@2|Bacteria,4NSS3@976|Bacteroidetes,2FTP8@200643|Bacteroidia	976|Bacteroidetes	S	toxin-antitoxin system toxin component, PIN family	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
TH3_k127_376724_0	497964.CfE428DRAFT_1743	7.77e-268	838.0	COG1166@1|root,COG1166@2|Bacteria,46S4T@74201|Verrucomicrobia	74201|Verrucomicrobia	E	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
TH3_k127_376724_1	497964.CfE428DRAFT_0749	1.439e-87	297.0	COG0327@1|root,COG0327@2|Bacteria	2|Bacteria	L	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	ybgI	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896	3.5.4.16	ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	NIF3
TH3_k127_376724_5	1403819.BATR01000133_gene4737	0.0002693	50.0	2FCQS@1|root,344TZ@2|Bacteria,46W38@74201|Verrucomicrobia,2IUKT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_376724_2	880072.Desac_1280	7.448e-58	212.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,2MQGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
TH3_k127_376724_4	909663.KI867150_gene1006	2.604e-07	52.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42P3K@68525|delta/epsilon subdivisions,2WMB8@28221|Deltaproteobacteria,2MREZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Inorganic H+ pyrophosphatase	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
TH3_k127_3787310_39	640081.Dsui_2056	8.057e-09	58.0	COG1403@1|root,COG1403@2|Bacteria,1RIEZ@1224|Proteobacteria,2VTF6@28216|Betaproteobacteria,2KWR0@206389|Rhodocyclales	206389|Rhodocyclales	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
TH3_k127_3787310_7	452637.Oter_1559	3.536e-85	295.0	2DVX4@1|root,33XIH@2|Bacteria,46VH6@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3787310_37	661478.OP10G_0157	5.073e-13	72.0	COG1783@1|root,COG1783@2|Bacteria	2|Bacteria	S	DNA packaging	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_6
TH3_k127_3787310_10	398579.Spea_2275	7.435e-62	224.0	COG3291@1|root,COG3291@2|Bacteria,1QC1P@1224|Proteobacteria,1T7PF@1236|Gammaproteobacteria,2QDB3@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3787310_42	401526.TcarDRAFT_1283	1.56e-06	60.0	COG1783@1|root,COG3780@1|root,COG5525@1|root,COG1783@2|Bacteria,COG3780@2|Bacteria,COG5525@2|Bacteria	2|Bacteria	S	Phage terminase large subunit (GpA)	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	HTH_3,Terminase_6
TH3_k127_3787310_12	1110502.TMO_2325	7.061e-50	188.0	28IAN@1|root,2Z8D8@2|Bacteria,1NJD6@1224|Proteobacteria,2U3QV@28211|Alphaproteobacteria,2JYIM@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain of unknown function (DUF4055)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4055
TH3_k127_3787310_36	1005395.CSV86_21761	1.594e-15	86.0	28IWE@1|root,2Z8UQ@2|Bacteria,1PS44@1224|Proteobacteria,1RRB1@1236|Gammaproteobacteria,1YXNS@136845|Pseudomonas putida group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3787310_13	1031288.AXAA01000048_gene768	5.614e-45	173.0	2BZ9Z@1|root,2Z97E@2|Bacteria,1U6NR@1239|Firmicutes,24FZN@186801|Clostridia,36GJA@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3787310_11	991905.SL003B_p0052	2.432e-51	192.0	28K5X@1|root,2Z9UF@2|Bacteria,1R3CT@1224|Proteobacteria,2U3AI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
TH3_k127_3787310_2	794903.OPIT5_12250	6.34e-133	435.0	COG4861@1|root,COG4861@2|Bacteria,46XWK@74201|Verrucomicrobia,3K9X1@414999|Opitutae	414999|Opitutae	S	Transcriptional regulator, AbiEi antitoxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_2
TH3_k127_3787310_46	102129.Lepto7375DRAFT_6804	0.0003094	52.0	COG0582@1|root,COG0582@2|Bacteria,1GF6X@1117|Cyanobacteria,1HG4G@1150|Oscillatoriales	1117|Cyanobacteria	L	Phage integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_integrase
TH3_k127_3787310_38	232346.JHQL01000002_gene1062	6.422e-13	78.0	COG4643@1|root,COG4643@2|Bacteria,1R5M0@1224|Proteobacteria,1RY0K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3631
TH3_k127_3787310_17	643562.Daes_0503	2.324e-34	134.0	COG0640@1|root,COG0640@2|Bacteria,1N19R@1224|Proteobacteria,42TRS@68525|delta/epsilon subdivisions,2WQHU@28221|Deltaproteobacteria,2MC8X@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	SMART regulatory protein ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
TH3_k127_3787310_27	1499967.BAYZ01000050_gene2842	2.748e-24	103.0	COG0526@1|root,COG0526@2|Bacteria,2NQ71@2323|unclassified Bacteria	2|Bacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Thioredoxin_3
TH3_k127_3787310_3	525904.Tter_1451	7.225e-128	424.0	COG1249@1|root,COG1249@2|Bacteria,2NNTI@2323|unclassified Bacteria	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
TH3_k127_3787310_28	1031288.AXAA01000034_gene2180	1.699e-23	107.0	COG0509@1|root,COG4273@1|root,COG0509@2|Bacteria,COG4273@2|Bacteria,1V6WV@1239|Firmicutes,24N5H@186801|Clostridia,36JKI@31979|Clostridiaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	DGC,GCV_H
TH3_k127_3787310_25	643648.Slip_2187	6.691e-25	110.0	COG4273@1|root,COG4273@2|Bacteria,1VBRH@1239|Firmicutes,24N2C@186801|Clostridia	186801|Clostridia	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
TH3_k127_3787310_18	643648.Slip_2186	1.58e-33	138.0	COG4273@1|root,COG4273@2|Bacteria,1UPTR@1239|Firmicutes,25HNZ@186801|Clostridia	186801|Clostridia	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
TH3_k127_3787310_21	643648.Slip_2185	1.849e-30	133.0	COG1764@1|root,COG1764@2|Bacteria,1VYMJ@1239|Firmicutes,2538T@186801|Clostridia	186801|Clostridia	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
TH3_k127_3787310_5	452637.Oter_4060	3.864e-98	327.0	COG0345@1|root,COG0345@2|Bacteria	2|Bacteria	E	pyrroline-5-carboxylate reductase activity	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
TH3_k127_3787310_19	452637.Oter_4059	1.957e-32	141.0	COG0526@1|root,COG0526@2|Bacteria,46W21@74201|Verrucomicrobia	74201|Verrucomicrobia	CO	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
TH3_k127_3787310_4	909663.KI867150_gene1425	2.055e-101	334.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria,2MS43@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
TH3_k127_3787310_29	402880.MmarC5_0718	3.513e-21	102.0	COG0655@1|root,arCOG02573@2157|Archaea,2XVMU@28890|Euryarchaeota,23QEP@183939|Methanococci	183939|Methanococci	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
TH3_k127_3787310_30	1304885.AUEY01000001_gene3204	5.788e-20	101.0	2DPAK@1|root,33193@2|Bacteria,1NDU6@1224|Proteobacteria,432ZD@68525|delta/epsilon subdivisions,2WYIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3787310_40	521674.Plim_0147	7.594e-08	61.0	2DMHQ@1|root,32RMG@2|Bacteria,2J02C@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Arsenical resistance operon trans-acting repressor ArsD	-	-	-	-	-	-	-	-	-	-	-	-	ArsD
TH3_k127_3787310_31	1408428.JNJP01000055_gene143	1.21e-18	91.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,42V3T@68525|delta/epsilon subdivisions,2WS3M@28221|Deltaproteobacteria,2MC9Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Helix-turn-helix domain	-	-	-	ko:K03892,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
TH3_k127_3787310_16	278957.ABEA03000004_gene4516	1.741e-34	138.0	COG0640@1|root,COG0640@2|Bacteria,46WF9@74201|Verrucomicrobia,3K8BI@414999|Opitutae	414999|Opitutae	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
TH3_k127_3787310_8	1396141.BATP01000003_gene5267	5.248e-71	244.0	COG0394@1|root,COG0394@2|Bacteria,46T52@74201|Verrucomicrobia,2IUEU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
TH3_k127_3787310_41	1280953.HOC_18234	6.001e-07	55.0	2EPBI@1|root,33GYA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3787310_6	556269.ACDQ01000009_gene1948	2.403e-95	331.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2VQVG@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
TH3_k127_3787310_24	1269813.ATUL01000021_gene759	3.876e-27	127.0	2DMHQ@1|root,32RMG@2|Bacteria,1RI3A@1224|Proteobacteria,1S7NG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Arsenical resistance operon trans-acting repressor arsD	arsD	-	-	-	-	-	-	-	-	-	-	-	ArsD
TH3_k127_3787310_0	530564.Psta_1209	1.385e-216	696.0	COG0003@1|root,COG0003@2|Bacteria,2IY37@203682|Planctomycetes	203682|Planctomycetes	P	TIGRFAM arsenite-activated ATPase (arsA)	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
TH3_k127_3787310_34	794903.OPIT5_07895	2.691e-16	80.0	COG2331@1|root,COG2331@2|Bacteria,46ZFV@74201|Verrucomicrobia,3K8G5@414999|Opitutae	414999|Opitutae	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3787310_45	1112216.JH594425_gene2614	0.0001643	51.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG4566@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,COG4566@2|Bacteria,1NRP8@1224|Proteobacteria,2TWP9@28211|Alphaproteobacteria,2KETS@204457|Sphingomonadales	204457|Sphingomonadales	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,GerE,HATPase_c,HisKA,PAS_10,Response_reg
TH3_k127_3787310_22	1156937.MFUM_270017	5.351e-30	132.0	COG2866@1|root,COG2866@2|Bacteria,46T00@74201|Verrucomicrobia,37GID@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
TH3_k127_3787310_1	478741.JAFS01000001_gene1976	5.099e-147	477.0	COG0798@1|root,COG0798@2|Bacteria,46UD3@74201|Verrucomicrobia,37FUU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
TH3_k127_3787310_35	1283300.ATXB01000001_gene1577	1.269e-15	79.0	COG0589@1|root,COG0589@2|Bacteria,1NGA1@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TH3_k127_3787310_14	1283300.ATXB01000001_gene1577	4.532e-44	167.0	COG0589@1|root,COG0589@2|Bacteria,1NGA1@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TH3_k127_3787310_9	521011.Mpal_2572	7.831e-67	235.0	COG4063@1|root,arCOG03221@2157|Archaea	2157|Archaea	H	Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step	mtrA-2	-	2.1.1.86	ko:K00577	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrA
TH3_k127_3787310_44	1410608.JNKX01000052_gene1502	8.511e-06	56.0	COG3385@1|root,COG3385@2|Bacteria,4NXT2@976|Bacteroidetes,2FRVS@200643|Bacteroidia	976|Bacteroidetes	L	hmm pf01609	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
TH3_k127_3787310_43	452637.Oter_1161	4.109e-06	53.0	COG4575@1|root,COG4575@2|Bacteria,46WFC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
TH3_k127_3787310_32	330214.NIDE1608	6.979e-17	89.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
TH3_k127_3787310_15	186497.PF0730	4.059e-39	159.0	arCOG07124@1|root,arCOG07124@2157|Archaea,2Y6Q6@28890|Euryarchaeota,2451X@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3787310_20	330214.NIDE3258	1.343e-31	134.0	COG0655@1|root,COG0655@2|Bacteria,3J192@40117|Nitrospirae	40117|Nitrospirae	S	NADPH-dependent FMN reductase	wrbA	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
TH3_k127_3787310_23	246197.MXAN_1806	2.19e-28	125.0	COG5483@1|root,COG5483@2|Bacteria,1N3XQ@1224|Proteobacteria,42WPT@68525|delta/epsilon subdivisions,2WRQ7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
TH3_k127_3787310_33	1403819.BATR01000075_gene2223	1.134e-16	80.0	COG5483@1|root,COG5483@2|Bacteria,46TB0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
TH3_k127_3788216_23	794903.OPIT5_10550	6.675e-15	85.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_3788216_2	886293.Sinac_6489	5.942e-166	561.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
TH3_k127_3788216_15	1123242.JH636435_gene2613	1.473e-53	199.0	COG1595@1|root,COG1595@2|Bacteria,2IZZP@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
TH3_k127_3788216_16	344747.PM8797T_26205	1.254e-51	206.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	DUF1863,PQQ,PQQ_2,PQQ_3
TH3_k127_3788216_3	344747.PM8797T_02169	1.231e-146	491.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2IXB6@203682|Planctomycetes	203682|Planctomycetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos,Methyltransf_25,PQQ_2
TH3_k127_3788216_21	794903.OPIT5_10630	6.324e-17	96.0	COG2133@1|root,COG3266@1|root,COG5184@1|root,COG2133@2|Bacteria,COG3266@2|Bacteria,COG5184@2|Bacteria,46Z90@74201|Verrucomicrobia,3K9IV@414999|Opitutae	414999|Opitutae	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	PA14
TH3_k127_3788216_24	345341.KUTG_02670	3.888e-06	61.0	COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria,2ICH5@201174|Actinobacteria,4E6DX@85010|Pseudonocardiales	201174|Actinobacteria	O	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_6
TH3_k127_3788216_0	344747.PM8797T_32040	1.386e-216	710.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,PQQ_2,PQQ_3
TH3_k127_3788216_18	504472.Slin_2680	2.705e-35	147.0	COG2133@1|root,COG3291@1|root,COG4625@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4625@2|Bacteria,4NJDV@976|Bacteroidetes,47NUN@768503|Cytophagia	976|Bacteroidetes	E	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,NPCBM,PA14,RicinB_lectin_2
TH3_k127_3788216_14	344747.PM8797T_31653	2.894e-58	219.0	2F8GG@1|root,340VA@2|Bacteria,2J3K0@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3788216_6	344747.PM8797T_31648	3.479e-109	371.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	tagS	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TH3_k127_3788216_11	344747.PM8797T_31643	6.066e-75	259.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	ko:K02003,ko:K05685,ko:K09810	ko02010,map02010	M00255,M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12,3.A.1.125	-	-	ABC_tran
TH3_k127_3788216_4	344747.PM8797T_31638	3.242e-143	471.0	COG0725@1|root,COG0725@2|Bacteria,2J08C@203682|Planctomycetes	203682|Planctomycetes	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
TH3_k127_3788216_8	344747.PM8797T_31633	2.475e-95	323.0	COG0555@1|root,COG0555@2|Bacteria,2IYJ3@203682|Planctomycetes	203682|Planctomycetes	O	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
TH3_k127_3788216_12	344747.PM8797T_31628	3.187e-71	247.0	COG3842@1|root,COG3842@2|Bacteria,2IZ85@203682|Planctomycetes	203682|Planctomycetes	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
TH3_k127_3788216_7	344747.PM8797T_31618	4.892e-104	352.0	COG0476@1|root,COG0476@2|Bacteria,2IY5K@203682|Planctomycetes	203682|Planctomycetes	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
TH3_k127_3788216_1	1396141.BATP01000060_gene4727	1.389e-212	705.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
TH3_k127_3788216_20	251221.35213566	9.091e-23	114.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3788216_9	378806.STAUR_6001	4.34e-87	306.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,4393J@68525|delta/epsilon subdivisions,2X49H@28221|Deltaproteobacteria,2YYJE@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TH3_k127_3788216_5	1173026.Glo7428_2698	1.852e-133	460.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TH3_k127_3788216_19	309807.SRU_1452	2.469e-24	119.0	2DRV2@1|root,33D77@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3788216_22	1142394.PSMK_09490	2.214e-16	93.0	COG2165@1|root,COG2165@2|Bacteria,2IXM1@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_3788216_25	1396418.BATQ01000168_gene1784	1.335e-05	59.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,46UNM@74201|Verrucomicrobia,2IVJ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Passenger-associated-transport-repeat	-	-	-	-	-	-	-	-	-	-	-	-	PATR
TH3_k127_3788216_10	118168.MC7420_7993	5.973e-79	291.0	COG0510@1|root,COG0510@2|Bacteria,1G023@1117|Cyanobacteria,1HEZ0@1150|Oscillatoriales	1117|Cyanobacteria	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
TH3_k127_3788216_17	1173026.Glo7428_4404	2.129e-43	181.0	COG0438@1|root,COG0438@2|Bacteria,1G0ZR@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TH3_k127_3788216_13	945550.VISI1226_09879	8.211e-59	218.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RYBJ@1236|Gammaproteobacteria,1XZ3M@135623|Vibrionales	135623|Vibrionales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TH3_k127_3788843_12	278957.ABEA03000021_gene1719	1.839e-08	68.0	COG1520@1|root,COG1520@2|Bacteria,46Z5C@74201|Verrucomicrobia,3K9I4@414999|Opitutae	414999|Opitutae	S	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3788843_10	1469557.JSWF01000021_gene726	1.96e-21	111.0	COG0739@1|root,COG3266@1|root,COG4886@1|root,COG0739@2|Bacteria,COG3266@2|Bacteria,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1I2GQ@117743|Flavobacteriia	976|Bacteroidetes	P	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TH3_k127_3788843_5	306281.AJLK01000102_gene3405	2.005e-71	246.0	COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3788843_1	886293.Sinac_6925	2.244e-163	527.0	COG0399@1|root,COG0399@2|Bacteria,2IYSK@203682|Planctomycetes	203682|Planctomycetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TH3_k127_3788843_3	240016.ABIZ01000001_gene3537	2.2e-138	480.0	COG0553@1|root,COG0553@2|Bacteria,46YZ0@74201|Verrucomicrobia,2ITIC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
TH3_k127_3788843_15	1214217.ALNF01000014_gene1478	5.664e-05	53.0	COG3944@1|root,COG3944@2|Bacteria,1V4ZF@1239|Firmicutes,4IR4A@91061|Bacilli,1WSAY@1307|Streptococcus suis	91061|Bacilli	M	Chain length determinant protein	cps4C	-	-	-	-	-	-	-	-	-	-	-	Wzz
TH3_k127_3788843_13	497321.C664_02540	4.8e-08	55.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2VK17@28216|Betaproteobacteria,2KY4N@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
TH3_k127_3788843_4	313590.MED134_09431	8.356e-98	328.0	COG2374@1|root,COG2374@2|Bacteria,4NI8T@976|Bacteroidetes,1I0TH@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TH3_k127_3788843_0	1123278.KB893448_gene1541	1.917e-190	611.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
TH3_k127_3788843_7	1279009.ADICEAN_02097	1.313e-33	145.0	COG0823@1|root,COG1649@1|root,COG2931@1|root,COG3055@1|root,COG3210@1|root,COG4733@1|root,COG0823@2|Bacteria,COG1649@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,4NPRK@976|Bacteroidetes	976|Bacteroidetes	U	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3788843_11	1197906.CAJQ02000023_gene2158	1.083e-12	80.0	COG2335@1|root,COG2335@2|Bacteria,1MZ8G@1224|Proteobacteria,2U5ZN@28211|Alphaproteobacteria,3JY4R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
TH3_k127_3788843_8	1232410.KI421415_gene3082	3.871e-32	128.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Smr protein MutS2	-	-	-	-	-	-	-	-	-	-	-	-	Smr
TH3_k127_3788843_6	1210884.HG799462_gene8139	3.774e-43	164.0	COG0454@1|root,COG0456@2|Bacteria,2J028@203682|Planctomycetes	203682|Planctomycetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TH3_k127_3788843_2	926549.KI421517_gene2208	1.169e-162	523.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47NGQ@768503|Cytophagia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	3.5.1.32	ko:K01451	ko00360,map00360	-	R01424	RC00096,RC00162	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TH3_k127_3788843_9	886293.Sinac_4672	5.172e-32	131.0	COG1403@1|root,COG1403@2|Bacteria,2J3RR@203682|Planctomycetes	203682|Planctomycetes	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
TH3_k127_3806954_3	1396141.BATP01000028_gene2285	1.502e-82	310.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
TH3_k127_3806954_4	497964.CfE428DRAFT_5731	4.263e-61	220.0	COG2197@1|root,COG2197@2|Bacteria,46UBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_3806954_2	1396141.BATP01000029_gene2231	1.305e-159	541.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
TH3_k127_3806954_0	497964.CfE428DRAFT_0324	0.0	1223.0	COG0178@1|root,COG0178@2|Bacteria,46SEB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
TH3_k127_3806954_6	1499967.BAYZ01000088_gene5142	6.793e-16	93.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,2NRIW@2323|unclassified Bacteria	2|Bacteria	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
TH3_k127_3806954_5	1157490.EL26_10960	2.069e-26	111.0	COG0316@1|root,COG0316@2|Bacteria,1V6IN@1239|Firmicutes,4HKN2@91061|Bacilli,278HH@186823|Alicyclobacillaceae	91061|Bacilli	S	Belongs to the HesB IscA family	yutM	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
TH3_k127_3806954_1	1396418.BATQ01000093_gene5884	2.166e-295	912.0	COG0422@1|root,COG0422@2|Bacteria,46S5R@74201|Verrucomicrobia,2ITWP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	ThiC-associated domain	-	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
TH3_k127_3823551_7	926550.CLDAP_13780	7.636e-93	320.0	COG2311@1|root,COG2311@2|Bacteria,2G8B7@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
TH3_k127_3823551_4	497964.CfE428DRAFT_6439	1.622e-142	455.0	COG0413@1|root,COG0413@2|Bacteria	2|Bacteria	H	3-methyl-2-oxobutanoate hydroxymethyltransferase activity	-	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
TH3_k127_3823551_5	497964.CfE428DRAFT_1804	5.021e-134	466.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
TH3_k127_3823551_8	497964.CfE428DRAFT_5731	1.73e-65	232.0	COG2197@1|root,COG2197@2|Bacteria,46UBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_3823551_3	382464.ABSI01000010_gene3213	4.127e-154	499.0	COG0673@1|root,COG0673@2|Bacteria,46UYM@74201|Verrucomicrobia,2IVG2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_3823551_0	497964.CfE428DRAFT_3010	0.0	1399.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,46TRH@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Tricorn protease PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
TH3_k127_3823551_2	497964.CfE428DRAFT_5350	8.478e-159	518.0	COG5267@1|root,COG5267@2|Bacteria,46SWV@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
TH3_k127_3823551_6	1403819.BATR01000042_gene1250	2.842e-99	337.0	COG4102@1|root,COG4102@2|Bacteria,46T50@74201|Verrucomicrobia,2IUKB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TH3_k127_3823551_9	1366050.N234_08390	2.74e-28	121.0	COG0527@1|root,COG0527@2|Bacteria,1REUY@1224|Proteobacteria,2VS69@28216|Betaproteobacteria,1K7HV@119060|Burkholderiaceae	2|Bacteria	E	ACT domain	-	-	1.1.1.3,2.7.2.4	ko:K00003,ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_6,Homoserine_dh,NAD_binding_3
TH3_k127_3823551_1	497964.CfE428DRAFT_0788	3.116e-177	558.0	COG0362@1|root,COG0362@2|Bacteria,46SDE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
TH3_k127_3828153_7	522306.CAP2UW1_0963	2.692e-07	53.0	COG3385@1|root,COG3385@2|Bacteria,1MXYG@1224|Proteobacteria,2VRWD@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase Tn5 dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_Tn5,Tnp_DNA_bind
TH3_k127_3828153_0	1396141.BATP01000060_gene4727	1.761e-224	741.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
TH3_k127_3828153_3	1218084.BBJK01000086_gene5778	1.15e-25	123.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria,2WI8K@28216|Betaproteobacteria,1KIR6@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Domain of unknown function (DUF4982)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
TH3_k127_3828153_6	1089545.KB913037_gene8403	4.086e-08	66.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2HSAI@201174|Actinobacteria,4ED2E@85010|Pseudonocardiales	201174|Actinobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3828153_4	153948.NAL212_2874	1.397e-12	81.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,371Z5@32003|Nitrosomonadales	28216|Betaproteobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
TH3_k127_3828153_1	497964.CfE428DRAFT_0066	3.304e-71	265.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
TH3_k127_3828153_2	1123242.JH636435_gene2613	3.493e-58	211.0	COG1595@1|root,COG1595@2|Bacteria,2IZZP@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
TH3_k127_3828153_5	498761.HM1_0137	2.208e-10	74.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
TH3_k127_3832889_0	641524.ADICYQ_4181	2.652e-64	252.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
TH3_k127_3871883_0	497964.CfE428DRAFT_1398	6.331e-272	863.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46U11@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TH3_k127_3871883_8	313612.L8106_03564	1.937e-12	69.0	COG0598@1|root,COG0598@2|Bacteria,1G4WV@1117|Cyanobacteria,1HEGB@1150|Oscillatoriales	1117|Cyanobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	CorA
TH3_k127_3871883_2	240016.ABIZ01000001_gene4794	8.75e-165	530.0	COG0006@1|root,COG0006@2|Bacteria,46U30@74201|Verrucomicrobia,2ITPD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
TH3_k127_3871883_3	240016.ABIZ01000001_gene4797	1.795e-163	529.0	COG3104@1|root,COG3104@2|Bacteria,46UAC@74201|Verrucomicrobia,2IU1T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
TH3_k127_3871883_1	886293.Sinac_3213	1.996e-213	680.0	COG4805@1|root,COG4805@2|Bacteria,2IXQZ@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
TH3_k127_3871883_4	1396418.BATQ01000175_gene2745	3.529e-81	278.0	COG1387@1|root,COG1387@2|Bacteria,46SMB@74201|Verrucomicrobia,2IU6X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
TH3_k127_3871883_6	1125863.JAFN01000001_gene1790	3.143e-42	161.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42UR1@68525|delta/epsilon subdivisions,2WPQ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TH3_k127_3871883_5	452637.Oter_2449	1.807e-66	233.0	COG0652@1|root,COG0652@2|Bacteria,46VEN@74201|Verrucomicrobia,3K7Y9@414999|Opitutae	414999|Opitutae	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
TH3_k127_3871883_10	1453505.JASY01000013_gene4343	0.0004876	49.0	2CIT3@1|root,32Y0C@2|Bacteria,4NUWR@976|Bacteroidetes,1I533@117743|Flavobacteriia,2NWGN@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4890
TH3_k127_3899227_6	391625.PPSIR1_34952	3.916e-08	61.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K21397	-	-	-	-	ko00000,ko02000	3.A.1	-	-	FHA,Trans_reg_C,Yop-YscD_cpl
TH3_k127_3899227_4	643562.Daes_0072	1.342e-29	123.0	2DQ60@1|root,334WQ@2|Bacteria,1NADI@1224|Proteobacteria,42WP8@68525|delta/epsilon subdivisions,2WRS6@28221|Deltaproteobacteria,2MD9Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
TH3_k127_3899227_3	1283300.ATXB01000001_gene2112	1.742e-46	170.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,1T12G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3899227_2	323848.Nmul_A2162	7.533e-48	177.0	COG1539@1|root,COG1539@2|Bacteria,1QVAP@1224|Proteobacteria,2WHHJ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
TH3_k127_3899227_1	530564.Psta_1651	9.157e-76	269.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,BAAT_C,Peptidase_S9
TH3_k127_3899227_5	1379270.AUXF01000002_gene1124	1.839e-12	70.0	COG0296@1|root,COG0296@2|Bacteria,1ZU2E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
TH3_k127_3930760_1	1123070.KB899251_gene679	7.713e-193	620.0	COG0488@1|root,COG0488@2|Bacteria,46SJA@74201|Verrucomicrobia,2ITVQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ABC transporter C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
TH3_k127_3930760_4	768710.DesyoDRAFT_1775	2.18e-133	449.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	B12-binding,Radical_SAM
TH3_k127_3930760_0	497964.CfE428DRAFT_1254	0.0	1298.0	COG4581@1|root,COG4581@2|Bacteria,46STC@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
TH3_k127_3930760_2	497964.CfE428DRAFT_2502	8.707e-188	608.0	COG0513@1|root,COG0513@2|Bacteria,46U0S@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
TH3_k127_3930760_3	382464.ABSI01000007_gene4191	1.828e-176	578.0	COG2833@1|root,COG2833@2|Bacteria,46YYE@74201|Verrucomicrobia,2ITUP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
TH3_k127_3930760_5	1396418.BATQ01000140_gene3197	1.88e-09	63.0	COG0607@1|root,COG0607@2|Bacteria,46VE6@74201|Verrucomicrobia,2IUCJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TH3_k127_3950122_1	404380.Gbem_0633	5.418e-07	56.0	COG1974@1|root,COG1974@2|Bacteria,1PEWX@1224|Proteobacteria,4303T@68525|delta/epsilon subdivisions,2WVGT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
TH3_k127_3950122_0	742766.HMPREF9455_02467	1.148e-13	85.0	COG4733@1|root,COG4733@2|Bacteria,4PMVV@976|Bacteroidetes,2G0IK@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
TH3_k127_3950122_2	1121904.ARBP01000022_gene3520	3.428e-05	49.0	COG1621@1|root,COG1621@2|Bacteria,4PNCP@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3979619_3	99598.Cal7507_2587	6.89e-09	61.0	COG0385@1|root,COG0385@2|Bacteria,1GJMF@1117|Cyanobacteria,1HMZI@1161|Nostocales	1117|Cyanobacteria	S	Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
TH3_k127_3979619_1	335543.Sfum_1471	2.222e-310	966.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,42P3J@68525|delta/epsilon subdivisions,2WKFS@28221|Deltaproteobacteria,2MQ9F@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
TH3_k127_3979619_0	420324.KI912022_gene340	0.0	1240.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2TRER@28211|Alphaproteobacteria,1JT1D@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
TH3_k127_3979619_2	497964.CfE428DRAFT_4406	5.215e-24	106.0	COG2985@1|root,COG2985@2|Bacteria,46TM7@74201|Verrucomicrobia	2|Bacteria	P	YidE YbjL duplication domain protein	yidE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
TH3_k127_3992727_5	443143.GM18_0903	2.066e-65	228.0	COG0110@1|root,COG0110@2|Bacteria,1MZV9@1224|Proteobacteria,43ARC@68525|delta/epsilon subdivisions,2WPNW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
TH3_k127_3992727_2	1396141.BATP01000036_gene3854	4.008e-132	432.0	COG0673@1|root,COG0673@2|Bacteria,46SAE@74201|Verrucomicrobia,2IU1W@203494|Verrucomicrobiae	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_3992727_6	1396141.BATP01000036_gene3853	6.086e-53	196.0	COG2148@1|root,COG2148@2|Bacteria,46TSZ@74201|Verrucomicrobia,2ITYD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
TH3_k127_3992727_0	317936.Nos7107_1299	1.036e-175	560.0	COG0579@1|root,COG0579@2|Bacteria,1G0XV@1117|Cyanobacteria,1HIW2@1161|Nostocales	1117|Cyanobacteria	S	PFAM FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
TH3_k127_3992727_1	272560.BPSL2686	5.074e-135	437.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2VJAD@28216|Betaproteobacteria,1K19M@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
TH3_k127_3992727_3	452637.Oter_3993	1.248e-119	393.0	COG1091@1|root,COG1091@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose reductase activity	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
TH3_k127_3992727_4	555778.Hneap_1487	1.789e-74	253.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria,1WVXE@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
TH3_k127_3995031_12	1444309.JAQG01000073_gene262	2.511e-22	99.0	COG2377@1|root,COG2377@2|Bacteria,1TSBU@1239|Firmicutes,4HAYA@91061|Bacilli,26SDJ@186822|Paenibacillaceae	91061|Bacilli	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
TH3_k127_3995031_3	1121335.Clst_0783	8.044e-181	572.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WHKM@541000|Ruminococcaceae	186801|Clostridia	G	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
TH3_k127_3995031_13	469383.Cwoe_4336	6.301e-09	65.0	2B4AG@1|root,31X1X@2|Bacteria,2GWKS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3995031_1	314230.DSM3645_26339	6.275e-194	614.0	COG2755@1|root,COG2755@2|Bacteria,2IYT9@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,Lipase_GDSL_2
TH3_k127_3995031_10	1385518.N798_14125	1.37e-34	137.0	COG3427@1|root,COG3427@2|Bacteria,2ISBF@201174|Actinobacteria,4FH30@85021|Intrasporangiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TH3_k127_3995031_5	1396418.BATQ01000092_gene5859	3.807e-104	349.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
TH3_k127_3995031_6	1396141.BATP01000042_gene1908	3.297e-84	283.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
TH3_k127_3995031_0	1396141.BATP01000042_gene1909	1.783e-247	782.0	COG3829@1|root,COG3829@2|Bacteria,46UZT@74201|Verrucomicrobia,2IVHE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
TH3_k127_3995031_2	452637.Oter_0554	2.823e-191	608.0	COG1236@1|root,COG1236@2|Bacteria,46UFS@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
TH3_k127_3995031_11	1397527.Q670_02705	7.297e-23	109.0	COG3637@1|root,COG3637@2|Bacteria,1NE9Q@1224|Proteobacteria,1T3ZI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3995031_4	1267534.KB906760_gene1239	1.071e-142	466.0	COG4325@1|root,COG4325@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
TH3_k127_3995031_8	1267533.KB906737_gene1998	2.377e-50	187.0	2E3FB@1|root,32YE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_3995031_7	1298867.AUES01000063_gene24	3.26e-62	226.0	COG1814@1|root,COG1814@2|Bacteria,1R469@1224|Proteobacteria,2U4KR@28211|Alphaproteobacteria,3JUX4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
TH3_k127_3995031_9	1298867.AUES01000018_gene4117	3.44e-45	164.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,2TVAP@28211|Alphaproteobacteria,3JRAG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
TH3_k127_4001430_1	452637.Oter_2587	1.053e-76	266.0	COG1333@1|root,COG1333@2|Bacteria,46SUY@74201|Verrucomicrobia,3K75U@414999|Opitutae	414999|Opitutae	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
TH3_k127_4001430_0	452637.Oter_2821	4.126e-173	571.0	COG0755@1|root,COG0755@2|Bacteria,46SIH@74201|Verrucomicrobia,3K7UF@414999|Opitutae	414999|Opitutae	O	PFAM cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
TH3_k127_4001430_5	1095743.HMPREF1054_0309	2.833e-21	101.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1Y8T2@135625|Pasteurellales	135625|Pasteurellales	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
TH3_k127_4001430_3	344747.PM8797T_03609	6.777e-53	197.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
TH3_k127_4001430_2	439235.Dalk_2979	3.532e-53	196.0	COG0420@1|root,COG0420@2|Bacteria	2|Bacteria	L	3'-5' exonuclease activity	-	-	3.1.1.53	ko:K03547,ko:K05970	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Metallophos,Metallophos_2
TH3_k127_4001430_4	1125701.HMPREF1221_01616	8.237e-26	122.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4009058_1	497964.CfE428DRAFT_3367	5.164e-161	518.0	COG3344@1|root,COG3344@2|Bacteria,46UR2@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
TH3_k127_4009058_4	247490.KSU1_B0180	1.436e-14	77.0	COG2841@1|root,COG2841@2|Bacteria,2J45A@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
TH3_k127_4009058_3	452637.Oter_3094	1.027e-81	297.0	COG2202@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria,46U96@74201|Verrucomicrobia	74201|Verrucomicrobia	KT	PFAM Stage II sporulation E family protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_3,PAS_4,SpoIIE
TH3_k127_4009058_2	794903.OPIT5_29485	3.387e-146	478.0	COG0621@1|root,COG0621@2|Bacteria,46S6B@74201|Verrucomicrobia,3K72N@414999|Opitutae	414999|Opitutae	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
TH3_k127_4009058_0	1396141.BATP01000004_gene5864	5.148e-161	513.0	COG2124@1|root,COG2124@2|Bacteria,46XKY@74201|Verrucomicrobia,2IW5R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TH3_k127_4017116_2	243090.RB605	1.394e-68	236.0	COG3119@1|root,COG3119@2|Bacteria,2J1ZQ@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TH3_k127_4017116_1	1403819.BATR01000027_gene886	3.593e-94	315.0	COG3345@1|root,COG3345@2|Bacteria,46XA8@74201|Verrucomicrobia,2IV69@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
TH3_k127_4017116_0	886293.Sinac_3462	4.245e-175	563.0	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
TH3_k127_4017116_3	595460.RRSWK_06385	2.055e-08	60.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2J2KJ@203682|Planctomycetes	203682|Planctomycetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
TH3_k127_4023404_14	1192034.CAP_0893	7.932e-66	235.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
TH3_k127_4023404_21	794903.OPIT5_29740	6.383e-10	72.0	COG2165@1|root,COG2165@2|Bacteria,46Y7T@74201|Verrucomicrobia,3K92V@414999|Opitutae	414999|Opitutae	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_10
TH3_k127_4023404_2	886293.Sinac_6489	7.861e-152	520.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
TH3_k127_4023404_8	102125.Xen7305DRAFT_00043350	5.987e-112	384.0	COG0591@1|root,COG0591@2|Bacteria,1G1JV@1117|Cyanobacteria,3VHP2@52604|Pleurocapsales	1117|Cyanobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
TH3_k127_4023404_11	28444.JODQ01000005_gene1401	3.552e-85	291.0	COG1572@1|root,COG2133@1|root,COG2374@1|root,COG3291@1|root,COG3828@1|root,COG1572@2|Bacteria,COG2133@2|Bacteria,COG2374@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,2GJFY@201174|Actinobacteria,4EKGY@85012|Streptosporangiales	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	ASH,CBM_6,DUF1349,F5_F8_type_C,GSDH,PKD,Ricin_B_lectin,ThuA
TH3_k127_4023404_13	452637.Oter_2056	7.827e-78	264.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BMC
TH3_k127_4023404_0	452637.Oter_2055	9.035e-209	656.0	COG4656@1|root,COG4656@2|Bacteria,46W83@74201|Verrucomicrobia	74201|Verrucomicrobia	C	RnfC Barrel sandwich hybrid domain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
TH3_k127_4023404_1	1396418.BATQ01000099_gene5573	7.792e-176	562.0	COG3119@1|root,COG3119@2|Bacteria,46XAA@74201|Verrucomicrobia,2IV6B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TH3_k127_4023404_12	497964.CfE428DRAFT_0879	1.741e-78	277.0	COG3494@1|root,COG3494@2|Bacteria,46SJ6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
TH3_k127_4023404_10	306281.AJLK01000140_gene1050	1.436e-86	308.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1JHUP@1189|Stigonemataceae	1117|Cyanobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,Response_reg
TH3_k127_4023404_15	1173026.Glo7428_2699	1.393e-52	193.0	COG0784@1|root,COG0784@2|Bacteria,1G548@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TH3_k127_4023404_4	1123508.JH636449_gene7422	2.985e-121	424.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TH3_k127_4023404_7	243090.RB12844	1.621e-112	372.0	COG3622@1|root,COG3622@2|Bacteria,2J4Z5@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_4023404_22	452637.Oter_0312	9.726e-08	66.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
TH3_k127_4023404_3	880072.Desac_0610	8.063e-138	469.0	COG0863@1|root,COG0863@2|Bacteria,1R8XS@1224|Proteobacteria	1224|Proteobacteria	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
TH3_k127_4023404_18	632518.Calow_0752	7.97e-24	102.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,42GTF@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
TH3_k127_4023404_19	289376.THEYE_A0819	3.69e-17	83.0	COG1837@1|root,COG1837@2|Bacteria	2|Bacteria	L	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
TH3_k127_4023404_9	1382315.JPOI01000001_gene3005	4.162e-87	293.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,1WE2C@129337|Geobacillus	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
TH3_k127_4023404_16	497964.CfE428DRAFT_0567	9.702e-45	165.0	COG0335@1|root,COG0335@2|Bacteria,46T0S@74201|Verrucomicrobia	74201|Verrucomicrobia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
TH3_k127_4023404_5	478741.JAFS01000002_gene722	7.754e-121	400.0	COG0124@1|root,COG0124@2|Bacteria,46S7Y@74201|Verrucomicrobia,37G1T@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
TH3_k127_4023404_17	1396141.BATP01000027_gene1118	6.364e-33	130.0	COG0776@1|root,COG0776@2|Bacteria,46T4V@74201|Verrucomicrobia,2IUR0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	bacterial (prokaryotic) histone like domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
TH3_k127_4023404_6	497964.CfE428DRAFT_2267	8.733e-120	393.0	COG0008@1|root,COG0008@2|Bacteria,46SQ3@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.17	ko:K01885,ko:K01894	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
TH3_k127_4023404_20	330214.NIDE4374	4.529e-10	62.0	COG1091@1|root,COG1091@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose reductase activity	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
TH3_k127_4036629_17	56110.Oscil6304_2123	2.056e-26	127.0	COG2931@1|root,COG2931@2|Bacteria,1G4IS@1117|Cyanobacteria,1HAFZ@1150|Oscillatoriales	1117|Cyanobacteria	Q	RTX toxins and related Ca2 binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind
TH3_k127_4036629_15	449447.MAE_29050	1.879e-48	199.0	COG1621@1|root,COG2931@1|root,COG1621@2|Bacteria,COG2931@2|Bacteria,1G32M@1117|Cyanobacteria	1117|Cyanobacteria	Q	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PPC,VCBS
TH3_k127_4036629_16	1123399.AQVE01000001_gene684	3.635e-48	184.0	COG3291@1|root,COG5295@1|root,COG3291@2|Bacteria,COG5295@2|Bacteria,1RGWM@1224|Proteobacteria,1SKIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	UW	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_3
TH3_k127_4036629_0	1380394.JADL01000003_gene4962	1.684e-213	690.0	COG1216@1|root,COG3934@1|root,COG1216@2|Bacteria,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Cellulase,Glyco_hydro_2_C,Glycos_transf_2
TH3_k127_4036629_13	497964.CfE428DRAFT_2511	1.1e-67	235.0	COG0417@1|root,COG0417@2|Bacteria,46SS2@74201|Verrucomicrobia	74201|Verrucomicrobia	L	RNase_H superfamily	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	RNase_H_2
TH3_k127_4036629_18	398767.Glov_1965	3.713e-23	109.0	COG0767@1|root,COG0767@2|Bacteria,1NSBS@1224|Proteobacteria,42ZGY@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
TH3_k127_4036629_19	401526.TcarDRAFT_1486	4.406e-23	111.0	COG1127@1|root,COG1127@2|Bacteria,1UGV0@1239|Firmicutes,4H251@909932|Negativicutes	909932|Negativicutes	Q	ABC transporter, ATP-binding protein	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
TH3_k127_4036629_21	243231.GSU1899	1.259e-05	57.0	COG1463@1|root,COG1463@2|Bacteria,1MY8D@1224|Proteobacteria,42TCA@68525|delta/epsilon subdivisions,2WP6I@28221|Deltaproteobacteria,43UDZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
TH3_k127_4036629_23	1121468.AUBR01000018_gene2682	0.0001166	53.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,42GBG@68295|Thermoanaerobacterales	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
TH3_k127_4036629_1	292459.STH2173	3.65e-163	559.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
TH3_k127_4036629_2	1121428.DESHY_110314___1	3.79e-154	528.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,260SC@186807|Peptococcaceae	186801|Clostridia	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
TH3_k127_4036629_8	1156937.MFUM_1020111	2.205e-118	396.0	COG1236@1|root,COG1236@2|Bacteria,46SQ0@74201|Verrucomicrobia,37FVJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Beta-Casp domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-Casp,Lactamase_B,RMMBL
TH3_k127_4036629_22	96561.Dole_1196	8.771e-05	53.0	COG4380@1|root,COG4380@2|Bacteria	2|Bacteria	D	Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	CsgG,DUF799,Gly-zipper_Omp,NosD,SPOR,TPR_16,TPR_2
TH3_k127_4036629_6	497964.CfE428DRAFT_0922	3.033e-129	422.0	COG2805@1|root,COG2805@2|Bacteria,46SJF@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	PFAM type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
TH3_k127_4036629_10	497964.CfE428DRAFT_3169	2.359e-91	317.0	COG1519@1|root,COG1519@2|Bacteria,46SK9@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase domain protein	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
TH3_k127_4036629_14	756272.Plabr_2390	1.867e-51	194.0	COG0705@1|root,COG0705@2|Bacteria,2IZJ7@203682|Planctomycetes	203682|Planctomycetes	S	Rhomboid family	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid,Rhomboid_N
TH3_k127_4036629_11	1121440.AUMA01000005_gene2574	2.61e-81	291.0	COG0546@1|root,COG3173@1|root,COG0546@2|Bacteria,COG3173@2|Bacteria,1R5MY@1224|Proteobacteria,435UQ@68525|delta/epsilon subdivisions,2X9D0@28221|Deltaproteobacteria,2MBGQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
TH3_k127_4036629_7	1121033.AUCF01000009_gene1173	1.077e-121	397.0	COG3958@1|root,COG3958@2|Bacteria,1N6QF@1224|Proteobacteria,2TTU8@28211|Alphaproteobacteria,2JSWY@204441|Rhodospirillales	204441|Rhodospirillales	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
TH3_k127_4036629_4	1121033.AUCF01000009_gene1174	8.43e-133	428.0	COG3959@1|root,COG3959@2|Bacteria,1MWRX@1224|Proteobacteria,2TRA2@28211|Alphaproteobacteria,2JSGM@204441|Rhodospirillales	204441|Rhodospirillales	G	COG3959 Transketolase, N-terminal subunit	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
TH3_k127_4036629_9	614083.AWQR01000023_gene151	1.051e-102	344.0	COG1062@1|root,COG1062@2|Bacteria	2|Bacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	-	-	1.1.1.1,1.1.1.284	ko:K00001,ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
TH3_k127_4036629_3	402777.KB235904_gene3439	6.394e-135	446.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1G2IU@1117|Cyanobacteria	1117|Cyanobacteria	M	TIGRFAM rfaE bifunctional protein, domain I	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,PfkB
TH3_k127_4036629_12	1121440.AUMA01000005_gene2575	1.139e-80	281.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,42QBV@68525|delta/epsilon subdivisions,2WQ8F@28221|Deltaproteobacteria,2MB41@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TH3_k127_4036629_5	652103.Rpdx1_1424	4.815e-132	429.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,3JRQ2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46,4.2.1.76,5.1.3.2	ko:K01710,ko:K01784,ko:K12450	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R00293,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
TH3_k127_4036629_20	234267.Acid_6160	3.161e-07	63.0	COG2340@1|root,COG4733@1|root,COG2340@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta_helix,CAP,PKD,fn3
TH3_k127_4047781_1	240016.ABIZ01000001_gene1588	2.84e-51	198.0	COG0673@1|root,COG0673@2|Bacteria,46TM9@74201|Verrucomicrobia,2ITZ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_4047781_4	1158292.JPOE01000002_gene3555	6.695e-25	107.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
TH3_k127_4047781_6	443143.GM18_2869	1.123e-09	61.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,42M86@68525|delta/epsilon subdivisions,2WIT1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
TH3_k127_4047781_3	1502851.FG93_02170	2.996e-43	181.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,2TSB7@28211|Alphaproteobacteria,3JUBZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Exo_endo_phos,PATR
TH3_k127_4047781_5	1210884.HG799465_gene12104	3.593e-16	91.0	2BRCH@1|root,32KB5@2|Bacteria,2J2TZ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4047781_7	1320556.AVBP01000012_gene3576	0.0001808	48.0	COG0342@1|root,COG0342@2|Bacteria,1NRIJ@1224|Proteobacteria,2UPCM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4047781_2	1158292.JPOE01000002_gene3555	1.968e-45	170.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
TH3_k127_4047781_0	530564.Psta_4256	8.081e-60	222.0	COG2010@1|root,COG2133@1|root,COG3474@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3474@2|Bacteria,2IY0D@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
TH3_k127_4065307_0	76114.ebA1946	8.012e-87	299.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,2KYAW@206389|Rhodocyclales	206389|Rhodocyclales	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
TH3_k127_4065307_1	886293.Sinac_2177	6.323e-68	242.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
TH3_k127_4065307_2	1472716.KBK24_0122700	8.658e-67	243.0	COG4974@1|root,COG4974@2|Bacteria,1QUHS@1224|Proteobacteria,2VMS7@28216|Betaproteobacteria,1JZVB@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
TH3_k127_4065307_3	179408.Osc7112_2825	1.613e-32	131.0	29WIV@1|root,30I53@2|Bacteria,1G5SB@1117|Cyanobacteria,1HB7E@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4085639_11	395495.Lcho_0773	4.098e-05	46.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,2VHUB@28216|Betaproteobacteria,1KPAP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
TH3_k127_4085639_5	909663.KI867150_gene711	2.368e-65	233.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,43A29@68525|delta/epsilon subdivisions,2X21K@28221|Deltaproteobacteria,2MS4J@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
TH3_k127_4085639_0	478741.JAFS01000002_gene146	8.234e-141	477.0	COG0793@1|root,COG0793@2|Bacteria,46S88@74201|Verrucomicrobia,37FVV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	tail specific protease	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
TH3_k127_4085639_4	1519464.HY22_08455	9.565e-68	235.0	COG0225@1|root,COG0225@2|Bacteria,1FE4X@1090|Chlorobi	1090|Chlorobi	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
TH3_k127_4085639_1	525904.Tter_1408	1.434e-107	362.0	COG2262@1|root,COG2262@2|Bacteria,2NNWI@2323|unclassified Bacteria	2|Bacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
TH3_k127_4085639_3	648996.Theam_0501	2.447e-68	243.0	COG0324@1|root,COG0324@2|Bacteria,2G3QA@200783|Aquificae	200783|Aquificae	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
TH3_k127_4085639_6	1265505.ATUG01000003_gene311	1.211e-55	205.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WNPT@28221|Deltaproteobacteria,2MIZH@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
TH3_k127_4085639_7	497964.CfE428DRAFT_1107	1.391e-42	163.0	COG1595@1|root,COG1595@2|Bacteria,46SZG@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_4085639_10	1248916.ANFY01000009_gene96	2.668e-12	81.0	COG3055@1|root,COG3055@2|Bacteria,1N85X@1224|Proteobacteria	1224|Proteobacteria	M	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4085639_2	670307.HYPDE_40263	6.563e-93	314.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,2TRX0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
TH3_k127_4085639_9	43989.cce_5192	2.306e-19	89.0	COG2963@1|root,COG2963@2|Bacteria,1GAAT@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
TH3_k127_408772_19	388051.AUFE01000129_gene4953	4.673e-06	49.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,1K2WH@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Elements of external origin	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23
TH3_k127_408772_20	402777.KB235904_gene3701	0.0001961	51.0	2E1K5@1|root,32WXN@2|Bacteria,1G8HZ@1117|Cyanobacteria	1117|Cyanobacteria	S	Immunity protein Imm1	-	-	-	-	-	-	-	-	-	-	-	-	Imm1
TH3_k127_408772_6	273068.TTE0217	5.482e-101	342.0	COG2377@1|root,COG2377@2|Bacteria,1TSBU@1239|Firmicutes,247S1@186801|Clostridia,42HVC@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
TH3_k127_408772_9	1280944.HY17_00425	7.724e-58	212.0	COG2273@1|root,COG2273@2|Bacteria,1PG8G@1224|Proteobacteria,2V8W4@28211|Alphaproteobacteria,43XPI@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
TH3_k127_408772_8	1210884.HG799462_gene7872	2.598e-60	218.0	COG0095@1|root,COG0095@2|Bacteria,2J0D8@203682|Planctomycetes	203682|Planctomycetes	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
TH3_k127_408772_1	1166018.FAES_1357	2.209e-223	700.0	COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,47N60@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
TH3_k127_408772_11	1121878.AUGL01000017_gene1759	1.05e-44	168.0	2CWKB@1|root,32SZW@2|Bacteria,1RD54@1224|Proteobacteria,1S4QG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_408772_0	748280.NH8B_1377	0.0	1295.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria,2KQCR@206351|Neisseriales	206351|Neisseriales	C	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
TH3_k127_408772_15	240016.ABIZ01000001_gene2135	5.295e-12	67.0	COG0583@1|root,COG0583@2|Bacteria,46TNE@74201|Verrucomicrobia,2IUPD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TH3_k127_408772_2	521674.Plim_3206	6.813e-192	617.0	COG3119@1|root,COG3119@2|Bacteria,2IXXP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
TH3_k127_408772_4	240016.ABIZ01000001_gene5895	3.478e-130	419.0	COG2133@1|root,COG2133@2|Bacteria,46ZKI@74201|Verrucomicrobia,2IVI9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_408772_10	1396418.BATQ01000091_gene5770	2.339e-46	196.0	COG2273@1|root,COG2755@1|root,COG3064@1|root,COG3204@1|root,COG3291@1|root,COG2273@2|Bacteria,COG2755@2|Bacteria,COG3064@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,46X9M@74201|Verrucomicrobia,2IV4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGM	Peptidase M60-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,M60-like_N,PA14,Peptidase_M60
TH3_k127_408772_5	1396141.BATP01000043_gene1929	1.121e-108	402.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
TH3_k127_408772_16	879243.Poras_0890	2.81e-10	76.0	COG3630@1|root,COG3630@2|Bacteria,4NIHN@976|Bacteroidetes,2FMSV@200643|Bacteroidia,22W1S@171551|Porphyromonadaceae	976|Bacteroidetes	C	Oxaloacetate decarboxylase, gamma chain	-	-	-	-	-	-	-	-	-	-	-	-	LTD,OAD_gamma
TH3_k127_408772_7	351160.RRC213	2.28e-66	262.0	COG3391@1|root,arCOG02544@1|root,arCOG02544@2157|Archaea,arCOG02562@2157|Archaea,2Y7T2@28890|Euryarchaeota,2NBM7@224756|Methanomicrobia	224756|Methanomicrobia	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
TH3_k127_408772_17	1250005.PHEL85_0454	6.756e-08	68.0	COG1404@1|root,COG2312@1|root,COG4935@1|root,COG1404@2|Bacteria,COG2312@2|Bacteria,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia,3VX3A@52959|Polaribacter	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
TH3_k127_408772_14	1043205.AFYF01000030_gene487	8.882e-13	85.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2I2T4@201174|Actinobacteria	201174|Actinobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_2,PQQ_2
TH3_k127_408772_3	1403819.BATR01000171_gene5859	1.671e-163	526.0	COG0265@1|root,COG0750@1|root,COG0265@2|Bacteria,COG0750@2|Bacteria	2|Bacteria	M	metalloendopeptidase activity	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
TH3_k127_408772_13	285535.JOEY01000051_gene1463	5.382e-25	111.0	COG3693@1|root,COG3693@2|Bacteria,2GJSN@201174|Actinobacteria	201174|Actinobacteria	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_10,Glyco_hydro_62,RicinB_lectin_2
TH3_k127_408772_12	1282362.AEAC466_10935	1.51e-27	114.0	COG3693@1|root,COG3693@2|Bacteria,1R8V3@1224|Proteobacteria	1224|Proteobacteria	G	Glycosyl hydrolase family 62	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_62
TH3_k127_4093608_1	240016.ABIZ01000001_gene2819	1.766e-183	591.0	COG5421@1|root,COG5421@2|Bacteria,46U8B@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
TH3_k127_4093608_3	671143.DAMO_1527	4.338e-108	358.0	COG0530@1|root,COG0530@2|Bacteria,2NPPD@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
TH3_k127_4093608_4	497964.CfE428DRAFT_2480	2.9e-34	138.0	2AEIE@1|root,314DU@2|Bacteria,46WQ3@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4093608_0	1403819.BATR01000007_gene187	0.0	1114.0	COG0013@1|root,COG0013@2|Bacteria,46SAY@74201|Verrucomicrobia,2ITJJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
TH3_k127_4093608_2	314230.DSM3645_28167	3.895e-110	372.0	COG3039@1|root,COG3039@2|Bacteria,2J1M4@203682|Planctomycetes	203682|Planctomycetes	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
TH3_k127_4095553_1	1349785.BAUG01000003_gene251	6.935e-22	105.0	COG3266@1|root,COG3291@1|root,COG4782@1|root,COG4886@1|root,COG3266@2|Bacteria,COG3291@2|Bacteria,COG4782@2|Bacteria,COG4886@2|Bacteria,4PMMS@976|Bacteroidetes,1I661@117743|Flavobacteriia	976|Bacteroidetes	O	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4095553_2	1304874.JAFY01000001_gene2612	1.969e-19	105.0	COG3210@1|root,COG4447@1|root,COG3210@2|Bacteria,COG4447@2|Bacteria,3TB3U@508458|Synergistetes	508458|Synergistetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TH3_k127_4095553_3	304371.MCP_2796	7.685e-16	93.0	arCOG06738@1|root,arCOG06738@2157|Archaea	2157|Archaea	O	extracellular matrix structural constituent	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	Beta_helix,Calx-beta,CarboxypepD_reg,NosD,Peptidase_S8
TH3_k127_4095553_0	65393.PCC7424_1997	8.887e-32	145.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1G4IS@1117|Cyanobacteria,3KKQ9@43988|Cyanothece	1117|Cyanobacteria	QU	PFAM Hemolysin-type calcium-binding region	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind
TH3_k127_4109715_6	314230.DSM3645_29396	0.000267	45.0	COG4968@1|root,COG4968@2|Bacteria,2IZCE@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_4109715_4	945713.IALB_0846	6.427e-17	93.0	COG1520@1|root,COG1572@1|root,COG3291@1|root,COG4733@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,Malectin,fn3
TH3_k127_4109715_1	452637.Oter_3025	9.325e-92	314.0	COG0684@1|root,COG0684@2|Bacteria,46VAD@74201|Verrucomicrobia,3K8HM@414999|Opitutae	414999|Opitutae	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
TH3_k127_4109715_2	1340493.JNIF01000004_gene737	2.785e-82	284.0	COG0329@1|root,COG0329@2|Bacteria,3Y7AU@57723|Acidobacteria	57723|Acidobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.2.1.41	ko:K01707	ko00053,ko01100,map00053,map01100	-	R02279	RC00678	ko00000,ko00001,ko01000	-	-	-	DHDPS
TH3_k127_4109715_0	401526.TcarDRAFT_0709	2.652e-219	689.0	COG4948@1|root,COG4948@2|Bacteria,1TUWS@1239|Firmicutes,4H2CE@909932|Negativicutes	909932|Negativicutes	M	mandelate racemase muconate lactonizing	-	-	4.2.1.40	ko:K01706	ko00053,ko01100,map00053,map01100	-	R02752,R08056	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
TH3_k127_4109715_5	641524.ADICYQ_2834	1.828e-06	51.0	COG2610@1|root,COG2610@2|Bacteria,4NJ5B@976|Bacteroidetes,47K2S@768503|Cytophagia	976|Bacteroidetes	EG	PFAM Gluconate transporter	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
TH3_k127_4109715_3	497964.CfE428DRAFT_4864	7.635e-40	153.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4113102_9	509190.Cseg_3935	5.592e-22	101.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,2TTUM@28211|Alphaproteobacteria,2KF2F@204458|Caulobacterales	204458|Caulobacterales	CO	cytochrome c biogenesis protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
TH3_k127_4113102_1	452637.Oter_0818	9.543e-253	787.0	COG0334@1|root,COG0334@2|Bacteria,46UBX@74201|Verrucomicrobia,3K7SK@414999|Opitutae	414999|Opitutae	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
TH3_k127_4113102_0	452637.Oter_0819	0.0	1292.0	COG0574@1|root,COG0574@2|Bacteria,46XFR@74201|Verrucomicrobia,3K763@414999|Opitutae	414999|Opitutae	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
TH3_k127_4113102_6	644282.Deba_0317	4.901e-45	173.0	COG1102@1|root,COG1102@2|Bacteria,1R4GX@1224|Proteobacteria,42QKV@68525|delta/epsilon subdivisions,2WJS2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
TH3_k127_4113102_5	517418.Ctha_0234	8.128e-52	191.0	COG1225@1|root,COG1225@2|Bacteria,1FF4E@1090|Chlorobi	1090|Chlorobi	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TH3_k127_4113102_7	697282.Mettu_1034	9.41e-45	169.0	COG0558@1|root,COG0558@2|Bacteria,1N35Q@1224|Proteobacteria,1T0Q8@1236|Gammaproteobacteria,1XFBQ@135618|Methylococcales	135618|Methylococcales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
TH3_k127_4113102_4	886293.Sinac_6924	2.089e-87	299.0	COG2159@1|root,COG2159@2|Bacteria,2IZB9@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
TH3_k127_4113102_2	886293.Sinac_6923	2.16e-126	408.0	COG2159@1|root,COG2159@2|Bacteria,2IZCY@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
TH3_k127_4113102_3	1535287.JP74_20325	2.979e-114	381.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,2U1KM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
TH3_k127_4113102_8	1396418.BATQ01000025_gene5257	9.757e-42	162.0	COG2940@1|root,COG2940@2|Bacteria,46W0B@74201|Verrucomicrobia,2IUGA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
TH3_k127_4113102_13	682795.AciX8_3725	5.143e-10	74.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
TH3_k127_4113102_10	1396141.BATP01000034_gene4198	2.347e-19	104.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
TH3_k127_4113102_12	8364.ENSXETP00000010179	3.904e-10	74.0	2CMMP@1|root,2QQVA@2759|Eukaryota,38DQG@33154|Opisthokonta,3BC84@33208|Metazoa,3CVS6@33213|Bilateria,487IG@7711|Chordata,48ZK4@7742|Vertebrata	33208|Metazoa	S	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
TH3_k127_4113102_11	1396141.BATP01000006_gene5432	2.735e-12	81.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
TH3_k127_4118429_0	1267533.KB906734_gene4022	5.612e-100	332.0	COG0438@1|root,COG0438@2|Bacteria,3Y5K5@57723|Acidobacteria,2JNE3@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4118429_1	1484460.JSWG01000009_gene629	2.205e-61	222.0	COG2356@1|root,COG2374@1|root,COG2911@1|root,COG3291@1|root,COG3391@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CHU_C,LTD,fn3
TH3_k127_4118429_2	1121895.Q765_20730	4.749e-39	154.0	COG1345@1|root,COG2374@1|root,COG3210@1|root,COG1345@2|Bacteria,COG2374@2|Bacteria,COG3210@2|Bacteria,4NFVP@976|Bacteroidetes,1IIIJ@117743|Flavobacteriia,2P0E0@237|Flavobacterium	976|Bacteroidetes	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3494,LTD
TH3_k127_4130852_1	768710.DesyoDRAFT_1525	6.012e-60	223.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,2644X@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA_3,sCache_3_2
TH3_k127_4130852_3	1304875.JAFZ01000001_gene1135	0.0003245	43.0	COG4585@1|root,COG4585@2|Bacteria,3TAVH@508458|Synergistetes	508458|Synergistetes	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
TH3_k127_4130852_2	326427.Cagg_3668	5.035e-53	195.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi,377BM@32061|Chloroflexia	32061|Chloroflexia	K	Sigma-70, region 4 type 2	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_4130852_0	443143.GM18_0105	0.0	1037.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42QGH@68525|delta/epsilon subdivisions,2WKTM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM multicopper oxidase type 2	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2
TH3_k127_4145133_22	391625.PPSIR1_09091	9.497e-12	77.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,43BQ2@68525|delta/epsilon subdivisions,2WQ6X@28221|Deltaproteobacteria,2Z2WS@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
TH3_k127_4145133_25	247490.KSU1_C0252	0.000449	46.0	2EJYM@1|root,33DP8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4145133_3	765869.BDW_03970	9.609e-157	541.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2MSR8@213481|Bdellovibrionales,2WJZF@28221|Deltaproteobacteria	213481|Bdellovibrionales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
TH3_k127_4145133_1	317936.Nos7107_4863	4.473e-177	568.0	COG1649@1|root,COG1649@2|Bacteria,1G42C@1117|Cyanobacteria,1HQTX@1161|Nostocales	1117|Cyanobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
TH3_k127_4145133_24	314264.ROS217_14991	1.566e-09	64.0	2ENFV@1|root,33G39@2|Bacteria,1NP5K@1224|Proteobacteria,2UJUH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4145133_17	497964.CfE428DRAFT_3472	1.053e-41	162.0	COG1579@1|root,COG1579@2|Bacteria,46T10@74201|Verrucomicrobia	74201|Verrucomicrobia	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
TH3_k127_4145133_4	1267535.KB906767_gene4768	5.387e-155	503.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4145133_5	497965.Cyan7822_5111	9.496e-153	491.0	COG0082@1|root,COG0082@2|Bacteria,1G12S@1117|Cyanobacteria,3KGGQ@43988|Cyanothece	1117|Cyanobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.aroC	Chorismate_synt
TH3_k127_4145133_21	246197.MXAN_4314	7.142e-14	76.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,42NX5@68525|delta/epsilon subdivisions,2WMJ4@28221|Deltaproteobacteria,2Z1G5@29|Myxococcales	28221|Deltaproteobacteria	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Rubrerythrin
TH3_k127_4145133_8	240292.Ava_3452	7.099e-98	340.0	COG5002@1|root,COG5002@2|Bacteria,1GQDS@1117|Cyanobacteria,1HME7@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TH3_k127_4145133_9	382464.ABSI01000007_gene4118	1.57e-88	297.0	COG0745@1|root,COG0745@2|Bacteria,46TFB@74201|Verrucomicrobia,2IUEX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TH3_k127_4145133_18	517418.Ctha_2510	7.149e-30	127.0	COG3258@1|root,COG3258@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3,DUF3365
TH3_k127_4145133_2	1121920.AUAU01000017_gene1239	7.15e-174	565.0	COG0281@1|root,COG0281@2|Bacteria,3Y43V@57723|Acidobacteria	57723|Acidobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
TH3_k127_4145133_10	1303518.CCALI_00782	2.213e-81	287.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
TH3_k127_4145133_11	1200792.AKYF01000018_gene5885	1.752e-79	286.0	COG0531@1|root,COG0531@2|Bacteria,1VS5Q@1239|Firmicutes,4HTCE@91061|Bacilli,275MC@186822|Paenibacillaceae	91061|Bacilli	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
TH3_k127_4145133_13	1408445.JHXP01000026_gene2302	3.032e-76	275.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1S5KR@1236|Gammaproteobacteria,1JGK2@118969|Legionellales	118969|Legionellales	M	Beta-eliminating lyase	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
TH3_k127_4145133_14	497964.CfE428DRAFT_1388	2.568e-66	231.0	COG1595@1|root,COG1595@2|Bacteria,46STJ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_4145133_20	497964.CfE428DRAFT_1390	8.943e-20	94.0	2ET1N@1|root,33KJT@2|Bacteria,46TA1@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4145133_16	411490.ANACAC_03351	4.425e-47	183.0	COG0371@1|root,COG0371@2|Bacteria,1V994@1239|Firmicutes	1239|Firmicutes	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH_2
TH3_k127_4145133_0	452637.Oter_1839	3.731e-259	814.0	COG5492@1|root,COG5492@2|Bacteria,46UXF@74201|Verrucomicrobia,3K8Z6@414999|Opitutae	414999|Opitutae	N	Putative collagen-binding domain of a collagenase	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
TH3_k127_4145133_6	497964.CfE428DRAFT_0138	8.583e-120	391.0	28ND0@1|root,2ZBFU@2|Bacteria,46UZ8@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4145133_23	485917.Phep_4007	1.021e-09	72.0	28KZC@1|root,2ZAEP@2|Bacteria,4NITB@976|Bacteroidetes,1IVQJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4145133_7	886293.Sinac_7535	7.789e-104	352.0	COG5434@1|root,COG5434@2|Bacteria,2IX4K@203682|Planctomycetes	2|Bacteria	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
TH3_k127_4145133_15	390989.JOEG01000007_gene674	3.598e-53	207.0	COG1572@1|root,COG1572@2|Bacteria,2HWQ1@201174|Actinobacteria,4DJWH@85008|Micromonosporales	201174|Actinobacteria	N	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
TH3_k127_4145133_12	1123242.JH636435_gene769	6.257e-79	275.0	2DBNR@1|root,2ZA54@2|Bacteria,2IYX9@203682|Planctomycetes	203682|Planctomycetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
TH3_k127_4149239_2	1112214.AHIS01000056_gene2938	2.283e-24	120.0	COG5512@1|root,COG5512@2|Bacteria,1R4BG@1224|Proteobacteria,2U415@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
TH3_k127_4149239_3	247490.KSU1_C1712	7.776e-22	112.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4149239_0	1267535.KB906767_gene4768	3.709e-132	444.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4149239_1	1198452.Jab_2c25040	1.218e-128	422.0	COG0657@1|root,COG0657@2|Bacteria,1N5QB@1224|Proteobacteria,2VPXR@28216|Betaproteobacteria,474PV@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	alpha/beta hydrolase fold	xynB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
TH3_k127_4149239_4	1151292.QEW_0427	7.683e-07	61.0	COG1652@1|root,COG1652@2|Bacteria,1VBP0@1239|Firmicutes,25DK4@186801|Clostridia	186801|Clostridia	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
TH3_k127_41918_9	251221.35211841	8.146e-07	58.0	COG1404@1|root,COG1404@2|Bacteria,1G8UV@1117|Cyanobacteria	1117|Cyanobacteria	O	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,VCBS
TH3_k127_41918_11	313606.M23134_07014	0.0003703	43.0	COG4974@1|root,COG4974@2|Bacteria,4NSQX@976|Bacteroidetes,47RQT@768503|Cytophagia	976|Bacteroidetes	L	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
TH3_k127_41918_12	32057.KB217478_gene6407	0.0004207	45.0	2E953@1|root,333DW@2|Bacteria,1G8VT@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_41918_1	247490.KSU1_B0100	5.504e-150	484.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
TH3_k127_41918_5	1201288.M900_A0014	6.502e-77	261.0	COG1838@1|root,COG1838@2|Bacteria,1R33Y@1224|Proteobacteria,43DIX@68525|delta/epsilon subdivisions,2MUNI@213481|Bdellovibrionales,2WK6Z@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit	-	-	4.2.1.2	ko:K01676,ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
TH3_k127_41918_0	478741.JAFS01000002_gene564	1.957e-166	533.0	COG0104@1|root,COG0104@2|Bacteria,46TDF@74201|Verrucomicrobia,37GDA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
TH3_k127_41918_8	365046.Rta_17060	8.035e-20	102.0	COG4447@1|root,COG4447@2|Bacteria,1PIDF@1224|Proteobacteria,2WBU7@28216|Betaproteobacteria,4AIC2@80864|Comamonadaceae	28216|Betaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_41918_4	1403819.BATR01000184_gene6352	2.7e-92	309.0	COG0020@1|root,COG0020@2|Bacteria,46SMY@74201|Verrucomicrobia,2IU5V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
TH3_k127_41918_7	497964.CfE428DRAFT_4834	3.115e-60	219.0	COG4589@1|root,COG4589@2|Bacteria,46SX9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
TH3_k127_41918_2	1396418.BATQ01000139_gene3250	6.973e-140	454.0	COG0743@1|root,COG0743@2|Bacteria,46S90@74201|Verrucomicrobia,2ITI1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
TH3_k127_41918_6	452637.Oter_4633	5.125e-72	261.0	COG0750@1|root,COG0750@2|Bacteria,46S9B@74201|Verrucomicrobia,3K73Q@414999|Opitutae	414999|Opitutae	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
TH3_k127_41918_3	497964.CfE428DRAFT_4831	5.068e-95	315.0	COG0821@1|root,COG0821@2|Bacteria,46SEF@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
TH3_k127_419563_2	497964.CfE428DRAFT_5224	2.301e-136	474.0	COG1473@1|root,COG1473@2|Bacteria,46V61@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
TH3_k127_419563_1	1121468.AUBR01000038_gene1965	1.475e-142	493.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,247RR@186801|Clostridia,42HW6@68295|Thermoanaerobacterales	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
TH3_k127_419563_0	886293.Sinac_7036	5.404e-166	532.0	COG4299@1|root,COG4299@2|Bacteria,2IX5Y@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_419563_6	1303518.CCALI_01258	2.262e-11	74.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_419563_7	1123508.JH636446_gene6227	6.337e-06	57.0	COG2165@1|root,COG2165@2|Bacteria,2J1RN@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_419563_8	1121946.AUAX01000016_gene4757	0.0001707	53.0	COG2755@1|root,COG3266@1|root,COG2755@2|Bacteria,COG3266@2|Bacteria,2I2V4@201174|Actinobacteria,4D9Z9@85008|Micromonosporales	201174|Actinobacteria	E	Parallel beta-helix repeats	pelX	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_2,CBM_35,CBM_6
TH3_k127_419563_5	1110502.TMO_0647	3.855e-33	138.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,2VEVK@28211|Alphaproteobacteria,2JYN8@204441|Rhodospirillales	204441|Rhodospirillales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TH3_k127_419563_3	1250232.JQNJ01000001_gene1869	3.237e-105	359.0	COG4733@1|root,COG4733@2|Bacteria,4PNY1@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
TH3_k127_419563_4	1123242.JH636434_gene3426	3.065e-96	324.0	COG1506@1|root,COG1506@2|Bacteria,2IXED@203682|Planctomycetes	203682|Planctomycetes	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
TH3_k127_4198644_9	382464.ABSI01000011_gene2813	4.668e-77	265.0	COG2972@1|root,COG2972@2|Bacteria,46TY3@74201|Verrucomicrobia,2IVUC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TH3_k127_4198644_11	1267535.KB906767_gene1118	1.439e-68	242.0	COG3279@1|root,COG3279@2|Bacteria,3Y4VI@57723|Acidobacteria,2JJIJ@204432|Acidobacteriia	204432|Acidobacteriia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TH3_k127_4198644_6	641524.ADICYQ_2355	1.626e-94	330.0	COG4403@1|root,COG4403@2|Bacteria,4PMC1@976|Bacteroidetes,47Y49@768503|Cytophagia	976|Bacteroidetes	V	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TH3_k127_4198644_12	1156937.MFUM_920008	6.231e-48	175.0	COG1259@1|root,COG1259@2|Bacteria,46SW6@74201|Verrucomicrobia,37GI8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
TH3_k127_4198644_13	240016.ABIZ01000001_gene908	9.034e-40	163.0	COG1466@1|root,COG1466@2|Bacteria,46T5Y@74201|Verrucomicrobia,2ITP3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
TH3_k127_4198644_15	478741.JAFS01000002_gene252	1.473e-13	77.0	COG1366@1|root,COG1366@2|Bacteria,46T4Z@74201|Verrucomicrobia,37GXU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	STAS domain	rsbS	-	-	-	-	-	-	-	-	-	-	-	STAS
TH3_k127_4198644_3	497964.CfE428DRAFT_3487	4.619e-137	475.0	COG4191@1|root,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
TH3_k127_4198644_2	886293.Sinac_5129	2.532e-218	685.0	COG4948@1|root,COG4948@2|Bacteria,2IXK2@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
TH3_k127_4198644_10	1379698.RBG1_1C00001G0109	7.825e-71	248.0	COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria	2|Bacteria	U	ABC 3 transport family	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
TH3_k127_4198644_8	247490.KSU1_D0783	3.627e-84	292.0	COG0803@1|root,COG0803@2|Bacteria,2J0IP@203682|Planctomycetes	203682|Planctomycetes	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
TH3_k127_4198644_4	247490.KSU1_D0782	6.716e-130	432.0	COG3170@1|root,COG3170@2|Bacteria,2J3MN@203682|Planctomycetes	203682|Planctomycetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4198644_5	1396141.BATP01000061_gene4541	9.845e-129	426.0	28N64@1|root,2ZBFG@2|Bacteria,46Z9S@74201|Verrucomicrobia,2IWQS@203494|Verrucomicrobiae	2|Bacteria	S	Peptidase of plants and bacteria	-	-	-	-	-	-	-	-	-	-	-	-	BSP
TH3_k127_4198644_0	481448.Minf_1559	0.0	1150.0	COG0653@1|root,COG0653@2|Bacteria,46SJC@74201|Verrucomicrobia,37G1Y@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
TH3_k127_4198644_16	661367.LLO_1892	3.979e-13	83.0	COG3250@1|root,COG4733@1|root,COG5492@1|root,COG3250@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Malectin,fn3
TH3_k127_4198644_14	481448.Minf_1759	1.273e-32	136.0	COG0095@1|root,COG0095@2|Bacteria,46T01@74201|Verrucomicrobia,37GRJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Biotin/lipoate A/B protein ligase family	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
TH3_k127_4198644_7	497964.CfE428DRAFT_0115	2.924e-94	314.0	COG0177@1|root,COG0177@2|Bacteria,46T2G@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
TH3_k127_4198644_1	330214.NIDE0577	1.484e-312	979.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
TH3_k127_4200073_18	268407.PWYN_09035	0.000334	50.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,26U3R@186822|Paenibacillaceae	91061|Bacilli	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
TH3_k127_4200073_0	1396141.BATP01000060_gene4727	1.384e-221	732.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
TH3_k127_4200073_16	1189620.AJXL01000074_gene3244	3.324e-09	68.0	COG1345@1|root,COG1361@1|root,COG1520@1|root,COG3291@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG1520@2|Bacteria,COG3291@2|Bacteria,4NEZF@976|Bacteroidetes,1HZ6F@117743|Flavobacteriia,2NSYB@237|Flavobacterium	976|Bacteroidetes	N	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4200073_9	382464.ABSI01000011_gene2968	7.793e-53	210.0	COG0515@1|root,COG0515@2|Bacteria	382464.ABSI01000011_gene2968|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4200073_11	760192.Halhy_1640	2.026e-25	112.0	COG0693@1|root,COG0693@2|Bacteria,4NQI1@976|Bacteroidetes,1IQJB@117747|Sphingobacteriia	976|Bacteroidetes	S	Intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
TH3_k127_4200073_17	1123073.KB899242_gene1643	2.501e-05	57.0	COG1520@1|root,COG5571@1|root,COG1520@2|Bacteria,COG5571@2|Bacteria	2|Bacteria	N	outer membrane autotransporter	yhjY	-	-	ko:K12287,ko:K12686	-	-	-	-	ko00000,ko02000,ko02044	1.B.12.8	-	-	Autotransporter,DUF4421,Lipase_GDSL
TH3_k127_4200073_15	246194.CHY_0024	2.089e-11	68.0	COG0432@1|root,COG0432@2|Bacteria,1V201@1239|Firmicutes,24FTY@186801|Clostridia,42G53@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
TH3_k127_4200073_14	497964.CfE428DRAFT_4431	1.517e-11	79.0	COG1361@1|root,COG1520@1|root,COG1572@1|root,COG3227@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	CHU_C,FTP,PQQ_2,Peptidase_M36
TH3_k127_4200073_10	497964.CfE428DRAFT_5098	2.824e-29	137.0	COG1075@1|root,COG1404@1|root,COG3055@1|root,COG3391@1|root,COG1075@2|Bacteria,COG1404@2|Bacteria,COG3055@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	1.1.3.6,3.2.1.4	ko:K01179,ko:K03333,ko:K12287	ko00500,ko00984,ko01100,ko01120,map00500,map00984,map01100,map01120	-	R01459,R06200,R11307,R11308	RC00146	ko00000,ko00001,ko01000,ko02044	-	GH5,GH9	-	Kelch_1,Laminin_G_3,Malectin
TH3_k127_4200073_3	1123399.AQVE01000001_gene684	8.175e-106	381.0	COG3291@1|root,COG5295@1|root,COG3291@2|Bacteria,COG5295@2|Bacteria,1RGWM@1224|Proteobacteria,1SKIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	UW	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_3
TH3_k127_4200073_7	234267.Acid_2129	7.213e-68	241.0	COG0693@1|root,COG0693@2|Bacteria,3Y3JB@57723|Acidobacteria	57723|Acidobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
TH3_k127_4200073_5	641524.ADICYQ_0788	4.548e-76	267.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TH3_k127_4200073_6	378806.STAUR_4743	1.943e-72	253.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,43A1N@68525|delta/epsilon subdivisions,2X25S@28221|Deltaproteobacteria,2YYJ4@29|Myxococcales	28221|Deltaproteobacteria	IQ	NAD dependent epimerase dehydratase family protein	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TH3_k127_4200073_8	177437.HRM2_24220	1.157e-54	199.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKJ7@28221|Deltaproteobacteria,2MK6F@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_4200073_1	1121440.AUMA01000005_gene2707	3.151e-135	440.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,42NAS@68525|delta/epsilon subdivisions,2WNAF@28221|Deltaproteobacteria,2M9I9@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the agmatine deiminase family	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
TH3_k127_4200073_2	886293.Sinac_2616	3.195e-133	432.0	COG0714@1|root,COG0714@2|Bacteria,2IY1M@203682|Planctomycetes	203682|Planctomycetes	S	ATPase associated with	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TH3_k127_4200073_13	324602.Caur_3413	2.115e-14	87.0	COG0497@1|root,COG1196@1|root,COG0497@2|Bacteria,COG1196@2|Bacteria,2GA8M@200795|Chloroflexi,37598@32061|Chloroflexia	32061|Chloroflexia	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4200073_12	349521.HCH_00950	2.466e-23	109.0	COG2339@1|root,COG2339@2|Bacteria	2|Bacteria	D	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
TH3_k127_4200073_4	1396141.BATP01000032_gene4314	1.141e-91	314.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
TH3_k127_4211432_9	1123508.JH636439_gene1132	4.222e-13	76.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
TH3_k127_4211432_5	1120953.AUBH01000005_gene2232	7.02e-38	155.0	COG3595@1|root,COG3595@2|Bacteria,1RFCY@1224|Proteobacteria,1S5RB@1236|Gammaproteobacteria,467PX@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
TH3_k127_4211432_6	439235.Dalk_3988	3.666e-36	143.0	COG3809@1|root,COG3809@2|Bacteria,1QSA6@1224|Proteobacteria	1224|Proteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
TH3_k127_4211432_0	1183438.GKIL_2151	2.836e-210	689.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
TH3_k127_4211432_2	1183438.GKIL_2152	1.395e-97	335.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TH3_k127_4211432_1	497964.CfE428DRAFT_0200	5.156e-153	491.0	COG2309@1|root,COG2309@2|Bacteria,46SAI@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM peptidase M29 aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
TH3_k127_4211432_4	497964.CfE428DRAFT_1407	1.43e-48	185.0	COG0582@1|root,COG0582@2|Bacteria,46W0S@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
TH3_k127_4211432_8	794903.OPIT5_01350	5.909e-23	100.0	COG0582@1|root,COG0582@2|Bacteria,46W0S@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
TH3_k127_4211432_7	1385935.N836_35430	7.44e-31	127.0	2EPF5@1|root,33H1T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4211432_10	749414.SBI_05800	2.435e-05	51.0	COG1484@1|root,COG1484@2|Bacteria,2GNJG@201174|Actinobacteria	201174|Actinobacteria	L	DNA replication protein	-	-	-	ko:K02315,ko:K11144	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
TH3_k127_4211432_3	1449357.JQLK01000001_gene1413	4.636e-73	250.0	COG0286@1|root,COG0286@2|Bacteria,1WI3E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
TH3_k127_4222930_3	1122132.AQYH01000005_gene433	2.711e-97	323.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,4B9N4@82115|Rhizobiaceae	28211|Alphaproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
TH3_k127_4222930_7	629265.PMA4326_11447	1.795e-37	146.0	COG0835@1|root,COG0835@2|Bacteria,1N0R3@1224|Proteobacteria,1SG9X@1236|Gammaproteobacteria,1Z7ZK@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	NT	COG0835 Chemotaxis signal transduction protein	wspB	-	-	ko:K13488	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	CheW
TH3_k127_4222930_2	240016.ABIZ01000001_gene190	9.573e-100	340.0	COG1352@1|root,COG1352@2|Bacteria,46U91@74201|Verrucomicrobia	74201|Verrucomicrobia	NT	Methyltransferase, chemotaxis proteins	-	-	-	-	-	-	-	-	-	-	-	-	CheR,TPR_2
TH3_k127_4222930_6	748247.AZKH_p0390	3.17e-56	205.0	COG0835@1|root,COG0835@2|Bacteria,1RIUD@1224|Proteobacteria,2VSFU@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	chemotaxis signal transduction protein	wspD	-	-	ko:K13489	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	CheW
TH3_k127_4222930_0	1403819.BATR01000024_gene821	1.901e-247	790.0	COG0643@1|root,COG0745@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,46UEP@74201|Verrucomicrobia,2IUVS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
TH3_k127_4222930_1	240016.ABIZ01000001_gene193	1.616e-117	388.0	COG2201@1|root,COG2201@2|Bacteria,46TVZ@74201|Verrucomicrobia,2IUSQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NT	CheB methylesterase	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,Response_reg
TH3_k127_4222930_5	309807.SRU_0542	4.05e-79	274.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
TH3_k127_4222930_4	497964.CfE428DRAFT_2305	1.133e-92	311.0	COG1692@1|root,COG1692@2|Bacteria,46SQ2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
TH3_k127_4222930_8	452637.Oter_0859	0.0003638	46.0	COG0349@1|root,COG0349@2|Bacteria,46SUU@74201|Verrucomicrobia,3K7PM@414999|Opitutae	414999|Opitutae	L	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
TH3_k127_427945_1	583355.Caka_3039	1.35e-159	524.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,46UC1@74201|Verrucomicrobia,3K9FB@414999|Opitutae	414999|Opitutae	C	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_427945_0	1291050.JAGE01000001_gene867	1.205e-173	571.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TH3_k127_427945_3	240016.ABIZ01000001_gene4912	8.803e-31	142.0	COG2010@1|root,COG2010@2|Bacteria,46URX@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
TH3_k127_427945_2	880526.KE386488_gene1576	1.316e-73	282.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_427945_4	1499967.BAYZ01000012_gene2475	5.944e-23	99.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	ydjG	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0019170,GO:0055114	-	ko:K18471	ko00640,map00640	-	R10718	RC00739	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
TH3_k127_4295428_4	794903.OPIT5_04765	6.466e-10	70.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_4295428_5	1403313.AXBR01000024_gene4802	7.703e-08	64.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,1ZCBA@1386|Bacillus	91061|Bacilli	G	invertase	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N,RicinB_lectin_2
TH3_k127_4295428_6	1521187.JPIM01000120_gene290	1.36e-05	56.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	lspI	-	-	ko:K02246,ko:K02457,ko:K02458	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
TH3_k127_4295428_0	1396141.BATP01000060_gene4560	4.715e-174	586.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
TH3_k127_4295428_1	452637.Oter_4174	1.227e-62	220.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
TH3_k127_4295428_3	1121897.AUGO01000002_gene2101	3.229e-24	104.0	2CENM@1|root,32S06@2|Bacteria,4NVR4@976|Bacteroidetes,1I5EG@117743|Flavobacteriia,2NX6R@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4332606_5	1168034.FH5T_21220	7.381e-82	282.0	COG0667@1|root,COG0667@2|Bacteria,4NP8D@976|Bacteroidetes,2FTGW@200643|Bacteroidia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TH3_k127_4332606_4	204669.Acid345_3213	1.247e-91	307.0	COG0563@1|root,COG0563@2|Bacteria,3Y421@57723|Acidobacteria,2JI14@204432|Acidobacteriia	57723|Acidobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	-	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
TH3_k127_4332606_1	661478.OP10G_0366	2.266e-172	548.0	COG4030@1|root,COG4030@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
TH3_k127_4332606_0	661478.OP10G_0382	1.711e-284	904.0	COG2605@1|root,COG2605@2|Bacteria	2|Bacteria	G	GHMP kinase	fkp	-	2.7.1.52	ko:K05305	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R03161	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Fucokinase,GHMP_kinases_C,GHMP_kinases_N
TH3_k127_4332606_3	313628.LNTAR_00950	2.66e-120	410.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
TH3_k127_4332606_2	661478.OP10G_2626	1.139e-158	522.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
TH3_k127_4332606_6	391612.CY0110_08276	2.272e-15	89.0	COG2304@1|root,COG3210@1|root,COG2304@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,DUF4214,HemolysinCabind,SdrD_B,VWA,VWA_2
TH3_k127_4358161_1	886293.Sinac_6489	4.324e-105	355.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
TH3_k127_4358161_2	497964.CfE428DRAFT_4864	2.346e-58	211.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4358161_0	1403819.BATR01000099_gene3304	1.28e-155	501.0	COG0644@1|root,COG0644@2|Bacteria,46U5W@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
TH3_k127_4371921_3	886293.Sinac_2716	5.866e-61	216.0	COG1477@1|root,COG1477@2|Bacteria,2IY0F@203682|Planctomycetes	203682|Planctomycetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
TH3_k127_4371921_1	452637.Oter_0820	1.286e-83	284.0	COG0012@1|root,COG0012@2|Bacteria	2|Bacteria	J	GTP binding	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
TH3_k127_4371921_5	1396141.BATP01000032_gene4325	5.643e-53	198.0	COG0265@1|root,COG0265@2|Bacteria,46W40@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4371921_0	1396141.BATP01000032_gene4324	1.78e-218	698.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia,2IU51@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
TH3_k127_4371921_2	1403819.BATR01000104_gene3588	5.658e-77	267.0	COG1082@1|root,COG1082@2|Bacteria,46UGG@74201|Verrucomicrobia,2IU3P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_4371921_4	497964.CfE428DRAFT_4945	1.013e-54	199.0	COG1541@1|root,COG1541@2|Bacteria,46SVW@74201|Verrucomicrobia	74201|Verrucomicrobia	H	AMP-binding enzyme C-terminal domain	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
TH3_k127_4384148_2	251221.35211765	1.329e-82	287.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TH3_k127_4384148_0	452637.Oter_1829	3.933e-189	619.0	COG0577@1|root,COG0577@2|Bacteria,46UIW@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TH3_k127_4384148_1	452637.Oter_1829	6.972e-117	392.0	COG0577@1|root,COG0577@2|Bacteria,46UIW@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TH3_k127_4394712_4	1121920.AUAU01000005_gene1005	7.593e-87	304.0	COG2271@1|root,COG2271@2|Bacteria,3Y98I@57723|Acidobacteria	57723|Acidobacteria	G	Organic Anion Transporter Polypeptide (OATP) family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TH3_k127_4394712_5	386456.JQKN01000023_gene72	1.177e-76	265.0	arCOG01778@1|root,arCOG01778@2157|Archaea,2XU6W@28890|Euryarchaeota	28890|Euryarchaeota	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
TH3_k127_4394712_17	1396141.BATP01000057_gene3046	6.21e-05	48.0	2AVZM@1|root,31MU0@2|Bacteria,46X67@74201|Verrucomicrobia,2IUMV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4394712_2	1267535.KB906767_gene1032	1.311e-97	332.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TH3_k127_4394712_9	478741.JAFS01000001_gene2028	3.382e-43	166.0	COG4798@1|root,COG4798@2|Bacteria,46T4I@74201|Verrucomicrobia,37GDY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
TH3_k127_4394712_7	1382356.JQMP01000003_gene2064	1.996e-51	194.0	COG0154@1|root,COG0154@2|Bacteria,2G7KI@200795|Chloroflexi,27YVS@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
TH3_k127_4394712_11	497964.CfE428DRAFT_0420	4.134e-39	152.0	2AY99@1|root,31QBJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4394712_12	552398.HMPREF0866_03064	1.319e-21	98.0	2ED8C@1|root,3374X@2|Bacteria,1W0C5@1239|Firmicutes,24S5N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Smr
TH3_k127_4394712_0	886293.Sinac_7347	1.731e-146	477.0	COG3507@1|root,COG3507@2|Bacteria,2J27X@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4394712_8	1499967.BAYZ01000137_gene111	6.59e-51	191.0	2FGP7@1|root,348IT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4394712_3	1403819.BATR01000104_gene3538	1.949e-87	302.0	COG3618@1|root,COG3618@2|Bacteria,46SN7@74201|Verrucomicrobia,2IUQ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
TH3_k127_4394712_13	935567.JAES01000033_gene858	1.37e-20	93.0	2EK70@1|root,33DXD@2|Bacteria,1NA99@1224|Proteobacteria,1SJFZ@1236|Gammaproteobacteria,1X82Y@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4394712_10	1140.Synpcc7942_1288	3.052e-42	162.0	COG3831@1|root,COG3831@2|Bacteria,1GPKY@1117|Cyanobacteria,1H3GN@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function (DUF4240)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4240
TH3_k127_4394712_16	794903.OPIT5_02510	3.364e-05	46.0	COG4974@1|root,COG4974@2|Bacteria,46UB9@74201|Verrucomicrobia,3K9DD@414999|Opitutae	414999|Opitutae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
TH3_k127_4394712_1	240016.ABIZ01000001_gene2202	3.483e-105	349.0	COG1801@1|root,COG1801@2|Bacteria,46TUG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
TH3_k127_4394712_6	471854.Dfer_0095	1.988e-73	256.0	COG1680@1|root,COG1680@2|Bacteria,4NGKK@976|Bacteroidetes,47N9R@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
TH3_k127_4395141_2	42256.RradSPS_2576	5.177e-87	295.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4CQ2Z@84995|Rubrobacteria	84995|Rubrobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
TH3_k127_4395141_3	476272.RUMHYD_00357	1.593e-40	156.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24I29@186801|Clostridia	186801|Clostridia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
TH3_k127_4395141_1	1042877.GQS_04965	8.142e-237	752.0	COG1894@1|root,COG4231@1|root,arCOG01609@2157|Archaea,arCOG04537@2157|Archaea,2XUYN@28890|Euryarchaeota,243V2@183968|Thermococci	183968|Thermococci	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
TH3_k127_4395141_0	903818.KI912268_gene1122	0.0	1130.0	COG3383@1|root,COG3383@2|Bacteria,3Y2KP@57723|Acidobacteria	57723|Acidobacteria	C	Formate dehydrogenase, alpha subunit	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
TH3_k127_4395141_4	161156.JQKW01000013_gene170	1.37e-26	112.0	COG0190@1|root,COG0190@2|Bacteria,2GH19@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
TH3_k127_4411053_2	316067.Geob_1216	1.123e-31	123.0	COG1449@1|root,COG1449@2|Bacteria,1PUYM@1224|Proteobacteria,42MQP@68525|delta/epsilon subdivisions,2WKP2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
TH3_k127_4411053_0	234267.Acid_6385	2.961e-202	644.0	COG0405@1|root,COG0405@2|Bacteria,3Y2I7@57723|Acidobacteria	57723|Acidobacteria	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
TH3_k127_4411053_1	1403819.BATR01000049_gene1427	3.207e-44	168.0	COG0424@1|root,COG0424@2|Bacteria,46VR6@74201|Verrucomicrobia,2IUHS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Maf-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Maf
TH3_k127_4411464_3	497964.CfE428DRAFT_3855	1.189e-39	148.0	COG0620@1|root,COG0620@2|Bacteria,46W8R@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Cobalamin-independent synthase, Catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
TH3_k127_4411464_0	1403819.BATR01000153_gene5138	6.267e-137	450.0	COG4948@1|root,COG4948@2|Bacteria,46S7G@74201|Verrucomicrobia,2IV9V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4411464_1	497964.CfE428DRAFT_0699	1.287e-85	301.0	COG0745@1|root,COG1235@1|root,COG0745@2|Bacteria,COG1235@2|Bacteria,46UKB@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
TH3_k127_4411464_2	1340493.JNIF01000003_gene3916	4.048e-85	300.0	COG2006@1|root,COG2006@2|Bacteria,3Y6M1@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
TH3_k127_442107_8	243090.RB605	1.063e-22	100.0	COG3119@1|root,COG3119@2|Bacteria,2J1ZQ@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TH3_k127_442107_13	762903.Pedsa_3064	6.199e-06	58.0	COG4409@1|root,COG4409@2|Bacteria,4NH3R@976|Bacteroidetes	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,CBM9_1
TH3_k127_442107_0	1123248.KB893381_gene944	0.0	1088.0	COG1874@1|root,COG1874@2|Bacteria,4PPRG@976|Bacteroidetes	976|Bacteroidetes	G	Hypothetical glycosyl hydrolase 6	-	-	-	-	-	-	-	-	-	-	-	-	GHL6
TH3_k127_442107_1	234267.Acid_7007	5e-324	1009.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10,GHL6,Glyco_hydro_42M,Polysacc_deac_1
TH3_k127_442107_6	1210884.HG799468_gene13605	1.793e-91	340.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Polysacc_deac_1,Polysacc_deac_3
TH3_k127_442107_10	452637.Oter_2210	3.247e-19	104.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.5.1.23	ko:K12349	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00099	R01494	RC00064,RC00328	ko00000,ko00001,ko00002,ko01000	-	-	-	Ceramidase_alk,Ceramidse_alk_C
TH3_k127_442107_5	314230.DSM3645_28727	1.048e-99	366.0	COG0613@1|root,COG0613@2|Bacteria,2IZFJ@203682|Planctomycetes	203682|Planctomycetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_442107_2	1123277.KB893176_gene3715	5.977e-231	724.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10,SLH
TH3_k127_442107_4	521674.Plim_1676	1.586e-101	341.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
TH3_k127_442107_3	1121904.ARBP01000013_gene349	1.078e-135	444.0	COG4948@1|root,COG4948@2|Bacteria,4NKNN@976|Bacteroidetes,47JKW@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
TH3_k127_442107_11	1540221.JQNI01000002_gene2916	3.26e-09	67.0	COG0491@1|root,COG0491@2|Bacteria,1WI41@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TH3_k127_442107_7	555779.Dthio_PD1267	4.217e-60	220.0	COG0667@1|root,COG0667@2|Bacteria,1R77F@1224|Proteobacteria,42Y4Z@68525|delta/epsilon subdivisions,2WTTZ@28221|Deltaproteobacteria,2MCP4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TH3_k127_442107_12	1123277.KB893176_gene3707	4.529e-06	52.0	COG2173@1|root,COG2173@2|Bacteria	2|Bacteria	M	zinc D-Ala-D-Ala carboxypeptidase activity	-	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15,SH3_3,SH3_4,VanY
TH3_k127_442107_9	1545701.LACWKB10_1508	1.059e-20	108.0	2C38I@1|root,2ZA75@2|Bacteria,1V0KH@1239|Firmicutes,4HURI@91061|Bacilli,3F5H4@33958|Lactobacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_442107_14	595460.RRSWK_00676	4.089e-05	53.0	COG1520@1|root,COG3533@1|root,COG1520@2|Bacteria,COG3533@2|Bacteria,2IWVC@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_4442565_4	497964.CfE428DRAFT_5616	1.401e-124	416.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	DLH,DUF1929,Glyoxal_oxid_N
TH3_k127_4442565_11	1283300.ATXB01000001_gene1507	5.569e-41	158.0	COG4636@1|root,COG4636@2|Bacteria,1R58B@1224|Proteobacteria,1S53A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
TH3_k127_4442565_1	1396141.BATP01000043_gene1929	6.604e-248	837.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
TH3_k127_4442565_12	1396141.BATP01000042_gene1928	3.052e-39	171.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	cotH	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
TH3_k127_4442565_5	1396141.BATP01000042_gene1927	4.413e-101	370.0	COG1520@1|root,COG4625@1|root,COG5295@1|root,COG1520@2|Bacteria,COG4625@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
TH3_k127_4442565_0	861299.J421_1753	1.155e-297	957.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
TH3_k127_4442565_16	1123242.JH636434_gene4592	1.465e-15	92.0	COG3712@1|root,COG3712@2|Bacteria,2IZ99@203682|Planctomycetes	203682|Planctomycetes	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,Laminin_G_3
TH3_k127_4442565_18	1121373.KB903632_gene508	1.704e-11	79.0	COG1520@1|root,COG1520@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
TH3_k127_4442565_14	1117315.AHCA01000001_gene2142	1.924e-32	148.0	COG3537@1|root,COG5492@1|root,COG3537@2|Bacteria,COG5492@2|Bacteria,1R4VD@1224|Proteobacteria,1RZJ5@1236|Gammaproteobacteria,2Q5IB@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	G	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
TH3_k127_4442565_15	1303518.CCALI_02579	8.909e-22	106.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_4442565_13	278957.ABEA03000004_gene4552	2.639e-33	133.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,46Y61@74201|Verrucomicrobia,3K8ZZ@414999|Opitutae	414999|Opitutae	KL	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ResIII
TH3_k127_4442565_8	278957.ABEA03000004_gene4552	2.714e-76	264.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,46Y61@74201|Verrucomicrobia,3K8ZZ@414999|Opitutae	414999|Opitutae	KL	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ResIII
TH3_k127_4442565_10	765914.ThisiDRAFT_1573	1.654e-46	173.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
TH3_k127_4442565_7	555779.Dthio_PD2029	3.421e-85	290.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WKYQ@28221|Deltaproteobacteria,2MARP@213115|Desulfovibrionales	28221|Deltaproteobacteria	EH	TIGRFAM para-aminobenzoate synthase, subunit I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
TH3_k127_4442565_17	316067.Geob_1294	3.068e-12	68.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WKYQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	TIGRFAM para-aminobenzoate synthase, subunit I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
TH3_k127_4442565_6	309801.trd_1049	1.65e-87	313.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi,27Z2G@189775|Thermomicrobia	189775|Thermomicrobia	E	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
TH3_k127_4442565_2	452637.Oter_4335	9.459e-131	436.0	COG0685@1|root,COG0685@2|Bacteria,46TD1@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Methylene-tetrahydrofolate reductase C terminal	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,MTHFR_C
TH3_k127_4442565_9	1244869.H261_12401	6.413e-56	207.0	COG1410@1|root,COG1410@2|Bacteria,1NSVT@1224|Proteobacteria	1224|Proteobacteria	E	Pterin binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Pterin_bind
TH3_k127_4442565_3	237368.SCABRO_00463	3.293e-128	415.0	COG2759@1|root,COG2759@2|Bacteria,2IX40@203682|Planctomycetes	203682|Planctomycetes	F	Formate--tetrahydrofolate ligase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
TH3_k127_4447201_0	794903.OPIT5_29980	2.031e-35	148.0	2EX0Y@1|root,33QC4@2|Bacteria,46UUA@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4447201_3	1120792.JAFV01000001_gene328	1.981e-08	64.0	2C0VP@1|root,32ZQ9@2|Bacteria,1NENB@1224|Proteobacteria,2UGGI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4447201_2	411490.ANACAC_00802	1.16e-20	98.0	2DVY7@1|root,32V0C@2|Bacteria,1VAXX@1239|Firmicutes,24P61@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4447201_4	679190.HMPREF0650_1053	1.851e-06	52.0	2DQYP@1|root,339EX@2|Bacteria,4NWWZ@976|Bacteroidetes,2FT6P@200643|Bacteroidia	976|Bacteroidetes	S	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
TH3_k127_445176_2	158189.SpiBuddy_2752	1.248e-43	168.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
TH3_k127_445176_0	1396141.BATP01000004_gene5795	4.011e-231	739.0	COG1053@1|root,COG1053@2|Bacteria,46S51@74201|Verrucomicrobia,2IVH2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
TH3_k127_445176_4	583355.Caka_0996	4.617e-06	50.0	COG3537@1|root,COG3537@2|Bacteria	2|Bacteria	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHB_HEX_C_1,F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b,Glyco_hydro_85,PA14
TH3_k127_445176_1	794903.OPIT5_20440	9.776e-51	191.0	COG5434@1|root,COG5434@2|Bacteria,46Y9S@74201|Verrucomicrobia,3K96M@414999|Opitutae	414999|Opitutae	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TH3_k127_4462100_0	761193.Runsl_3999	1.022e-135	438.0	COG1082@1|root,COG1082@2|Bacteria,4NKFY@976|Bacteroidetes,47N9K@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_4462100_2	497964.CfE428DRAFT_5731	4.6e-29	129.0	COG2197@1|root,COG2197@2|Bacteria,46UBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_4462100_4	661478.OP10G_0968	9.366e-12	77.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_4462100_6	1341181.FLJC2902T_10060	1.17e-05	59.0	COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,4NG09@976|Bacteroidetes,1HY3Z@117743|Flavobacteriia,2NU61@237|Flavobacterium	976|Bacteroidetes	O	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
TH3_k127_4462100_1	1396141.BATP01000060_gene4563	1.757e-71	262.0	COG0457@1|root,COG0457@2|Bacteria,46W3Y@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16
TH3_k127_4462100_5	247490.KSU1_C1333	2.315e-10	70.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_4462100_3	1303518.CCALI_00933	6.578e-12	74.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_44623_2	290397.Adeh_0749	1.825e-07	58.0	COG1215@1|root,COG1215@2|Bacteria,1MW1E@1224|Proteobacteria,42ZKN@68525|delta/epsilon subdivisions,2WUTQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TH3_k127_44623_0	452637.Oter_0358	9.296e-100	361.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,46YZC@74201|Verrucomicrobia,3K9WB@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
TH3_k127_44623_1	1123070.KB899269_gene2382	1.959e-49	185.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia,2IU42@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
TH3_k127_4462584_4	305700.B447_20945	1.459e-58	211.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria,2KV2M@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
TH3_k127_4462584_2	177437.HRM2_38050	2.063e-138	448.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria,2MJ9S@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
TH3_k127_4462584_0	497964.CfE428DRAFT_0990	4.606e-262	827.0	COG0514@1|root,COG0514@2|Bacteria,46S7V@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM ATP-dependent DNA helicase, RecQ family	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
TH3_k127_4462584_1	1121438.JNJA01000001_gene2267	1.48e-223	714.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria,2M85I@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
TH3_k127_4462584_5	497964.CfE428DRAFT_1901	4.068e-29	119.0	COG0236@1|root,COG0236@2|Bacteria,46T18@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TH3_k127_4462584_3	349741.Amuc_1327	2.716e-59	210.0	COG0304@1|root,COG0304@2|Bacteria,46SBU@74201|Verrucomicrobia,2ITS2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TH3_k127_4467243_1	709986.Deima_0518	2.856e-153	504.0	COG1092@1|root,COG1092@2|Bacteria,1WK2R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	PFAM S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
TH3_k127_4467243_2	1254432.SCE1572_02560	5.216e-139	456.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2YTUX@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TH3_k127_4467243_7	1096930.L284_00460	4.083e-05	55.0	COG5349@1|root,COG5349@2|Bacteria,1N0PN@1224|Proteobacteria,2UBSH@28211|Alphaproteobacteria,2K5S3@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
TH3_k127_4467243_4	1267534.KB906755_gene4489	2.655e-87	301.0	COG0842@1|root,COG0842@2|Bacteria,3Y4H7@57723|Acidobacteria,2JN2Y@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
TH3_k127_4467243_3	661478.OP10G_2908	1.394e-116	383.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	ybhF-C	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
TH3_k127_4467243_0	316067.Geob_2761	4.626e-240	771.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,43TPJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
TH3_k127_4467243_5	243090.RB4375	3.014e-24	120.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF642
TH3_k127_4467243_6	1198452.Jab_2c29700	1.431e-06	62.0	COG3227@1|root,COG3227@2|Bacteria,1R61F@1224|Proteobacteria,2VUWX@28216|Betaproteobacteria,474TB@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Thermolysin metallopeptidase, alpha-helical domain	-	-	-	ko:K20273	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	FTP,Peptidase_M4,Peptidase_M4_C
TH3_k127_4470411_1	1454004.AW11_02523	8.878e-06	56.0	COG3385@1|root,COG3385@2|Bacteria,1QT8J@1224|Proteobacteria,2VP4B@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
TH3_k127_4470411_0	497964.CfE428DRAFT_3486	0.0	1495.0	COG1038@1|root,COG1038@2|Bacteria,46S8N@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Conserved carboxylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
TH3_k127_450653_4	761193.Runsl_3324	3.278e-10	67.0	COG2072@1|root,COG2072@2|Bacteria,4PP2U@976|Bacteroidetes,47YFT@768503|Cytophagia	976|Bacteroidetes	P	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
TH3_k127_450653_2	497964.CfE428DRAFT_4879	3.144e-51	204.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,CBM_6,CHB_HEX_C_1,Glyco_hydro_43,Laminin_G_3,Pectate_lyase_3,RicinB_lectin_2
TH3_k127_450653_0	886293.Sinac_4099	1.353e-76	280.0	COG1506@1|root,COG1506@2|Bacteria,2J24Y@203682|Planctomycetes	203682|Planctomycetes	E	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
TH3_k127_450653_1	411902.CLOBOL_01842	3.139e-76	274.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,24AE7@186801|Clostridia,21ZBJ@1506553|Lachnoclostridium	186801|Clostridia	M	Mandelate racemase muconate lactonizing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
TH3_k127_450653_3	861299.J421_4528	3.046e-30	121.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Barstar,CBM_48,Esterase
TH3_k127_451571_3	627192.SLG_27470	4.259e-27	113.0	28J0M@1|root,2Z8XS@2|Bacteria,1RKDT@1224|Proteobacteria,2U9QW@28211|Alphaproteobacteria,2KA4X@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_451571_4	794903.OPIT5_14770	6.939e-12	76.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_451571_2	661478.OP10G_1032	2.168e-44	186.0	COG4354@1|root,COG4354@2|Bacteria	2|Bacteria	G	intracellular protein transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF608,Glyco_hydr_116N
TH3_k127_451571_0	661478.OP10G_1031	3.47e-257	827.0	COG1621@1|root,COG4354@1|root,COG1621@2|Bacteria,COG4354@2|Bacteria	2|Bacteria	G	intracellular protein transport	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,DUF608,Glyco_hydr_116N,VCBS
TH3_k127_451571_1	485913.Krac_11430	1.256e-97	330.0	COG2936@1|root,COG2936@2|Bacteria,2G85Q@200795|Chloroflexi	2|Bacteria	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
TH3_k127_4518502_27	13689.BV96_01053	4.066e-20	94.0	COG1961@1|root,COG1961@2|Bacteria,1N6DV@1224|Proteobacteria,2TVBV@28211|Alphaproteobacteria,2K65D@204457|Sphingomonadales	204457|Sphingomonadales	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TH3_k127_4518502_26	1048834.TC41_1912	6.366e-26	110.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli	91061|Bacilli	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
TH3_k127_4518502_23	497964.CfE428DRAFT_6605	3.799e-32	127.0	COG0211@1|root,COG0211@2|Bacteria,46T48@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
TH3_k127_4518502_11	497964.CfE428DRAFT_0322	8.738e-110	367.0	COG0536@1|root,COG0536@2|Bacteria,46SBS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
TH3_k127_4518502_8	382464.ABSI01000002_gene4277	1.514e-140	455.0	COG0012@1|root,COG0012@2|Bacteria,46S8D@74201|Verrucomicrobia,2ITV8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
TH3_k127_4518502_19	382464.ABSI01000013_gene1727	3.138e-57	208.0	COG1388@1|root,COG1388@2|Bacteria,46T61@74201|Verrucomicrobia	74201|Verrucomicrobia	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LysM
TH3_k127_4518502_17	240016.ABIZ01000001_gene621	3.234e-64	237.0	COG4714@1|root,COG4714@2|Bacteria,46WYQ@74201|Verrucomicrobia,2IUN8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF2167)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2167
TH3_k127_4518502_21	1192034.CAP_8221	2.248e-49	191.0	2C9T2@1|root,347D0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4518502_31	1385521.N803_05605	6.086e-06	52.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4FG9T@85021|Intrasporangiaceae	201174|Actinobacteria	M	sugar transferase	epsL	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
TH3_k127_4518502_22	497964.CfE428DRAFT_2435	8.264e-47	177.0	COG0546@1|root,COG0546@2|Bacteria,46SW1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,HAD_2
TH3_k127_4518502_25	706587.Desti_4133	3.28e-26	118.0	28JYU@1|root,2Z9NZ@2|Bacteria,1N5J2@1224|Proteobacteria,42UJJ@68525|delta/epsilon subdivisions,2X7XY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4518502_10	583355.Caka_0067	8.977e-119	389.0	COG0437@1|root,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,3K7GM@414999|Opitutae	2|Bacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4,Fer4_7
TH3_k127_4518502_7	448385.sce4706	8.494e-143	466.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2YWI0@29|Myxococcales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
TH3_k127_4518502_4	2340.JV46_09630	1.717e-192	612.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
TH3_k127_4518502_9	1403819.BATR01000183_gene6316	5.169e-122	408.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp,OMP_b-brl
TH3_k127_4518502_16	886293.Sinac_2497	6.462e-74	281.0	COG1595@1|root,COG2373@1|root,COG1595@2|Bacteria,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K03088,ko:K06894	-	-	-	-	ko00000,ko03021	-	-	-	A2M_N,CarboxypepD_reg,Sigma70_r2,Sigma70_r4_2
TH3_k127_4518502_1	497964.CfE428DRAFT_0818	7.704e-282	891.0	COG0046@1|root,COG0046@2|Bacteria,46S8Y@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
TH3_k127_4518502_3	330214.NIDE2536	7.323e-217	689.0	COG0021@1|root,COG0021@2|Bacteria,3J0MM@40117|Nitrospirae	40117|Nitrospirae	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
TH3_k127_4518502_29	316274.Haur_4882	1.081e-12	79.0	2EE19@1|root,337W3@2|Bacteria,2G8U2@200795|Chloroflexi,375HC@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LIM, zinc-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DA1-like
TH3_k127_4518502_24	1089550.ATTH01000001_gene181	7.483e-31	130.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,1FJDT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
TH3_k127_4518502_14	1297742.A176_07035	1.671e-81	303.0	COG0860@1|root,COG0860@2|Bacteria,1NTG0@1224|Proteobacteria	1224|Proteobacteria	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
TH3_k127_4518502_0	1396141.BATP01000032_gene4423	4.672e-284	891.0	COG5297@1|root,COG5297@2|Bacteria,46UD4@74201|Verrucomicrobia,2IVIH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4518502_15	1499967.BAYZ01000095_gene4228	1.211e-74	258.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
TH3_k127_4518502_28	278957.ABEA03000041_gene2093	1.242e-19	100.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,3K770@414999|Opitutae	414999|Opitutae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
TH3_k127_4518502_32	867845.KI911784_gene1416	1.39e-05	54.0	2EGCD@1|root,33A46@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF4190
TH3_k127_4518502_6	452637.Oter_2109	4.42e-167	533.0	COG0180@1|root,COG0180@2|Bacteria,46SA6@74201|Verrucomicrobia,3K7UW@414999|Opitutae	414999|Opitutae	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
TH3_k127_4518502_18	257314.LJ_0003	1.423e-61	226.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,3F3Q1@33958|Lactobacillaceae	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
TH3_k127_4518502_13	269799.Gmet_1782	5.694e-89	301.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,43TDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
TH3_k127_4518502_20	1384056.N787_02850	1.246e-51	198.0	2F24D@1|root,33V2Z@2|Bacteria,1NV0Y@1224|Proteobacteria,1SN7D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4518502_2	243233.MCA2119	4.045e-257	799.0	COG1449@1|root,COG1449@2|Bacteria,1R3Z3@1224|Proteobacteria,1RNRC@1236|Gammaproteobacteria,1XG1U@135618|Methylococcales	135618|Methylococcales	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
TH3_k127_4518502_5	1283300.ATXB01000001_gene664	5.201e-169	540.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,1RYKS@1236|Gammaproteobacteria,1XFWC@135618|Methylococcales	135618|Methylococcales	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	hDGE_amylase
TH3_k127_4518502_12	472759.Nhal_0095	2.003e-99	327.0	COG0297@1|root,COG0297@2|Bacteria,1P7F2@1224|Proteobacteria,1RZVJ@1236|Gammaproteobacteria,1WX4C@135613|Chromatiales	135613|Chromatiales	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
TH3_k127_4537715_7	290397.Adeh_2900	1.927e-51	192.0	COG0671@1|root,COG0671@2|Bacteria,1MWK1@1224|Proteobacteria,431Z2@68525|delta/epsilon subdivisions,2WWQX@28221|Deltaproteobacteria,2Z1G7@29|Myxococcales	28221|Deltaproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
TH3_k127_4537715_3	1286632.P278_07760	7.43e-266	837.0	COG3345@1|root,COG3345@2|Bacteria,4PMM4@976|Bacteroidetes	976|Bacteroidetes	G	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4537715_0	1123242.JH636435_gene1245	0.0	1107.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
TH3_k127_4537715_11	1123242.JH636435_gene1245	1.869e-12	69.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
TH3_k127_4537715_9	679926.Mpet_1520	3.634e-26	112.0	arCOG03403@1|root,arCOG03403@2157|Archaea,2Y5T8@28890|Euryarchaeota	28890|Euryarchaeota	K	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
TH3_k127_4537715_8	485917.Phep_1253	2.321e-36	153.0	COG4409@1|root,COG4409@2|Bacteria,4P1PN@976|Bacteroidetes	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TH3_k127_4537715_13	189426.PODO_28355	1.864e-05	51.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,4H9RK@91061|Bacilli,26QNT@186822|Paenibacillaceae	91061|Bacilli	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
TH3_k127_4537715_4	497964.CfE428DRAFT_6180	7.407e-122	407.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	2|Bacteria	S	SMART Pyrrolo-quinoline quinone	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
TH3_k127_4537715_2	1267535.KB906767_gene1828	1.798e-282	889.0	COG3518@1|root,COG3518@2|Bacteria	2|Bacteria	S	anti-sigma factor antagonist activity	iraD	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033554,GO:0042176,GO:0042177,GO:0043856,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K11897,ko:K21637	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
TH3_k127_4537715_1	616991.JPOO01000003_gene1322	5.917e-295	926.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,23G5Z@178469|Arenibacter	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
TH3_k127_4537715_6	497964.CfE428DRAFT_4864	7.477e-68	238.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4537715_5	886293.Sinac_6489	6.205e-103	349.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
TH3_k127_4541116_0	452637.Oter_0693	2.292e-172	548.0	COG0019@1|root,COG0019@2|Bacteria,46WJD@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM Orn DAP Arg decarboxylase 2	-	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TH3_k127_4541116_1	794903.OPIT5_23665	6.384e-78	267.0	COG0730@1|root,COG0730@2|Bacteria,46V74@74201|Verrucomicrobia,3K8YW@414999|Opitutae	414999|Opitutae	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TH3_k127_4541116_2	1127673.GLIP_1568	5.515e-39	156.0	COG3832@1|root,COG3832@2|Bacteria,1RDGX@1224|Proteobacteria,1S4FQ@1236|Gammaproteobacteria,4675R@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TH3_k127_4667711_1	497964.CfE428DRAFT_2718	1.876e-108	367.0	COG0142@1|root,COG0142@2|Bacteria,46S62@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
TH3_k127_4667711_0	761193.Runsl_4624	1.028e-173	556.0	COG1501@1|root,COG1501@2|Bacteria,4NH0T@976|Bacteroidetes,47TMI@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 31	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Glyco_hydro_31
TH3_k127_4733908_3	794903.OPIT5_07690	3.369e-66	251.0	COG3170@1|root,COG3170@2|Bacteria,46Y8C@74201|Verrucomicrobia,3K93X@414999|Opitutae	414999|Opitutae	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4733908_6	547042.BACCOPRO_02222	1.884e-07	64.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxidN1,DUF3370,DUF4985,GHL10,Melibiase,Metallophos,MetallophosC,MetallophosN,SLH,WG_beta_rep
TH3_k127_4733908_2	886293.Sinac_3681	4.285e-119	411.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	bgaB	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_14,Glyco_hydro_42,Glyco_hydro_42M
TH3_k127_4733908_4	1396141.BATP01000047_gene3930	7.865e-65	227.0	COG3476@1|root,COG3476@2|Bacteria,46SXT@74201|Verrucomicrobia,2IVZD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	TspO/MBR family	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
TH3_k127_4733908_5	472759.Nhal_2122	1.952e-37	148.0	COG0702@1|root,COG0702@2|Bacteria,1QV7M@1224|Proteobacteria,1T2N4@1236|Gammaproteobacteria,1WYK0@135613|Chromatiales	135613|Chromatiales	GM	intermediate-associated protein 30	-	-	-	-	-	-	-	-	-	-	-	-	CIA30
TH3_k127_4733908_7	196367.JNFG01000216_gene660	5.108e-05	51.0	COG0702@1|root,COG0702@2|Bacteria,1MZ0C@1224|Proteobacteria,2VNMR@28216|Betaproteobacteria,1K4VX@119060|Burkholderiaceae	28216|Betaproteobacteria	GM	Nad-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_3,Epimerase,NAD_binding_10
TH3_k127_4733908_1	349521.HCH_06395	4.342e-171	552.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,1RP3U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TH3_k127_4733908_0	1250005.PHEL85_3386	5.137e-175	581.0	COG0433@1|root,COG0433@2|Bacteria,4NVJM@976|Bacteroidetes,1I7IY@117743|Flavobacteriia,3VX4H@52959|Polaribacter	976|Bacteroidetes	S	TraM recognition site of TraD and TraG	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,TraG-D_C,TrwB_AAD_bind
TH3_k127_4760458_1	1123242.JH636434_gene5443	2.874e-123	401.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TH3_k127_4760458_0	886293.Sinac_6968	4.527e-137	445.0	COG4654@1|root,COG4654@2|Bacteria,2IX0M@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
TH3_k127_4804835_0	1210884.HG799469_gene14219	9.998e-108	366.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
TH3_k127_4804835_1	337075.U4L094	1.448e-06	60.0	2993U@1|root,2RG5A@2759|Eukaryota,38E92@33154|Opisthokonta,3NXE3@4751|Fungi,3QR0B@4890|Ascomycota	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4806720_5	1122931.AUAE01000031_gene2866	2.097e-42	165.0	COG1653@1|root,COG1653@2|Bacteria,4NG6U@976|Bacteroidetes,2FRMG@200643|Bacteroidia,2310A@171551|Porphyromonadaceae	976|Bacteroidetes	G	Periplasmic copper-binding protein (NosD)	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Beta_helix,DUF1565
TH3_k127_4806720_8	349741.Amuc_0982	7.096e-07	59.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	DNase_NucA_NucB,Endonuclea_NS_2,RHS_repeat
TH3_k127_4806720_3	240016.ABIZ01000001_gene5629	3.35e-58	211.0	COG2912@1|root,COG2912@2|Bacteria	2|Bacteria	P	Transglutaminase-like superfamily	CP_0628	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2,VIT
TH3_k127_4806720_1	926550.CLDAP_07020	2.27e-115	377.0	COG3293@1|root,COG3293@2|Bacteria,2G7YC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
TH3_k127_4806720_7	1499967.BAYZ01000095_gene4080	4.015e-10	70.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Peptidase_C39,RHS_repeat
TH3_k127_4806720_2	497964.CfE428DRAFT_6409	8.798e-99	345.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
TH3_k127_4806720_6	497964.CfE428DRAFT_6409	9.454e-11	68.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
TH3_k127_4806720_0	382464.ABSI01000005_gene1011	5.938e-162	526.0	COG1219@1|root,COG1219@2|Bacteria,46U7E@74201|Verrucomicrobia,2IVDM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
TH3_k127_4806720_4	1121957.ATVL01000006_gene2545	6.165e-50	184.0	COG1670@1|root,COG1670@2|Bacteria,4NMRH@976|Bacteroidetes,47QKT@768503|Cytophagia	976|Bacteroidetes	J	Domain of unknown function (DUF4202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4202
TH3_k127_4898287_1	1150599.MPHLEI_02793	5.308e-29	136.0	COG3209@1|root,COG3209@2|Bacteria,2I60K@201174|Actinobacteria,2375A@1762|Mycobacteriaceae	201174|Actinobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,RCC1_2
TH3_k127_4898287_0	762903.Pedsa_2424	1.735e-106	385.0	COG3209@1|root,COG3210@1|root,COG3291@1|root,COG4733@1|root,COG5492@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,4NDZC@976|Bacteroidetes,1J0Y4@117747|Sphingobacteriia	976|Bacteroidetes	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB,TIG
TH3_k127_4928618_1	1313304.CALK_1499	6.897e-100	332.0	COG0363@1|root,COG0363@2|Bacteria	2|Bacteria	G	glucosamine-6-phosphate deaminase activity	nagB	GO:0003674,GO:0003824,GO:0004342,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0006044,GO:0006046,GO:0006047,GO:0006048,GO:0006054,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016054,GO:0016787,GO:0016853,GO:0016860,GO:0016861,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0019239,GO:0019262,GO:0019438,GO:0019752,GO:0034641,GO:0034654,GO:0042737,GO:0042802,GO:0043436,GO:0043877,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046348,GO:0046349,GO:0046395,GO:0046483,GO:0055086,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901362,GO:1901575,GO:1901576	3.1.1.31,3.5.99.6	ko:K01057,ko:K02080,ko:K02564	ko00030,ko00052,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00052,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035,R08365	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_02959,iECB_1328.ECB_03008,iECD_1391.ECD_03008,iECNA114_1301.ECNA114_3225,iECSF_1327.ECSF_2979,iYO844.BSU02360,iYO844.BSU35020,iZ_1308.Z0825	Glucosamine_iso,PIG-L
TH3_k127_4928618_2	1266908.AQPB01000038_gene531	1.284e-08	63.0	COG3428@1|root,COG3428@2|Bacteria,1N3Z5@1224|Proteobacteria,1SAN2@1236|Gammaproteobacteria,1WYRT@135613|Chromatiales	135613|Chromatiales	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
TH3_k127_4928618_0	1313304.CALK_1498	1.363e-107	360.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_4966148_0	1121011.AUCB01000052_gene1387	1.577e-120	433.0	COG1554@1|root,COG1554@2|Bacteria,4NHVP@976|Bacteroidetes,1I8HC@117743|Flavobacteriia,23I16@178469|Arenibacter	976|Bacteroidetes	G	hydrolase, family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4966148_2	869213.JCM21142_93371	2.508e-65	256.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,47KQM@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
TH3_k127_4966148_1	595460.RRSWK_05080	4.212e-114	379.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	scrB	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
TH3_k127_4991235_2	1123248.KB893385_gene4912	5.064e-177	557.0	COG0363@1|root,COG0363@2|Bacteria,4P0EP@976|Bacteroidetes	976|Bacteroidetes	G	glucosamine-6-phosphate deaminase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4991235_5	1123248.KB893385_gene4913	8.867e-88	297.0	COG2120@1|root,COG2120@2|Bacteria,4P03X@976|Bacteroidetes	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TH3_k127_4991235_6	1403819.BATR01000083_gene2425	1.293e-53	198.0	COG1595@1|root,COG1595@2|Bacteria,46TV8@74201|Verrucomicrobia,2IVT7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
TH3_k127_4991235_4	1396141.BATP01000021_gene180	2.1e-100	359.0	COG0515@1|root,COG0515@2|Bacteria	1396141.BATP01000021_gene180|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_4991235_3	452637.Oter_2957	2.037e-117	387.0	COG1244@1|root,COG1244@2|Bacteria	2|Bacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	-
TH3_k127_4991235_0	452637.Oter_2956	4.477e-226	711.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
TH3_k127_4991235_1	243090.RB11088	1.035e-199	639.0	COG0457@1|root,COG0457@2|Bacteria,2IYBX@203682|Planctomycetes	203682|Planctomycetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
TH3_k127_4991235_7	382464.ABSI01000011_gene2813	1.059e-40	155.0	COG2972@1|root,COG2972@2|Bacteria,46TY3@74201|Verrucomicrobia,2IVUC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TH3_k127_5026659_1	234267.Acid_2132	3.188e-104	345.0	COG1028@1|root,COG1028@2|Bacteria,3Y7BE@57723|Acidobacteria	57723|Acidobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TH3_k127_5026659_4	1242864.D187_001577	9.445e-06	58.0	COG3420@1|root,COG3420@2|Bacteria,1R5QH@1224|Proteobacteria	1224|Proteobacteria	P	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TH3_k127_5026659_0	1242864.D187_008109	5.521e-124	407.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42PV7@68525|delta/epsilon subdivisions,2WKXE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
TH3_k127_5026659_3	640512.BC1003_5144	4.084e-07	53.0	COG1064@1|root,COG1064@2|Bacteria,1P0UC@1224|Proteobacteria,2VPCZ@28216|Betaproteobacteria,1KGVQ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
TH3_k127_5026659_5	395961.Cyan7425_5164	0.0002065	44.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TH3_k127_5026659_2	234267.Acid_6639	5.243e-45	171.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
TH3_k127_5037113_1	929556.Solca_3240	2.542e-146	468.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1IQQY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S9, prolyl oligopeptidase, catalytic domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
TH3_k127_5037113_5	1123242.JH636435_gene944	2.073e-90	316.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_5037113_3	1234364.AMSF01000079_gene1843	1.435e-108	368.0	COG1680@1|root,COG1680@2|Bacteria,1RBDE@1224|Proteobacteria,1RYDP@1236|Gammaproteobacteria,1X4U9@135614|Xanthomonadales	135614|Xanthomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TH3_k127_5037113_14	452637.Oter_1389	3.231e-44	165.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TH3_k127_5037113_26	1026882.MAMP_01168	2.098e-07	62.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,460M7@72273|Thiotrichales	72273|Thiotrichales	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8
TH3_k127_5037113_25	1396141.BATP01000060_gene4647	4.788e-09	59.0	COG0515@1|root,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
TH3_k127_5037113_8	1296416.JACB01000027_gene4076	6.395e-67	239.0	2BWKA@1|root,32QZQ@2|Bacteria,4P163@976|Bacteroidetes,1I86M@117743|Flavobacteriia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TH3_k127_5037113_22	237368.SCABRO_03851	3.254e-17	91.0	COG2165@1|root,COG2165@2|Bacteria,2J0Q6@203682|Planctomycetes	203682|Planctomycetes	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_5037113_4	1123242.JH636435_gene944	8.934e-108	368.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_5037113_10	497964.CfE428DRAFT_0215	1.901e-58	213.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	cya1	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Guanylate_cyc
TH3_k127_5037113_23	1303518.CCALI_02394	1.695e-15	87.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_5037113_24	1303518.CCALI_00378	7.723e-15	84.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_5037113_0	497964.CfE428DRAFT_4557	1.831e-190	605.0	COG2133@1|root,COG2133@2|Bacteria,46U0G@74201|Verrucomicrobia	74201|Verrucomicrobia	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5037113_12	756272.Plabr_1201	3.974e-53	206.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IXKV@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,GSDH,NPCBM,ThuA
TH3_k127_5037113_27	545697.HMPREF0216_03070	9.546e-07	61.0	COG1196@1|root,COG1538@1|root,COG3250@1|root,COG1196@2|Bacteria,COG1538@2|Bacteria,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,36F2A@31979|Clostridiaceae	186801|Clostridia	G	family 2, TIM barrel	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,FIVAR,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3,NPCBM
TH3_k127_5037113_2	481448.Minf_0686	4.561e-109	359.0	COG0090@1|root,COG0090@2|Bacteria,46S71@74201|Verrucomicrobia,37FZV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
TH3_k127_5037113_16	794903.OPIT5_02410	2.291e-34	133.0	COG0185@1|root,COG0185@2|Bacteria,46T4G@74201|Verrucomicrobia,3K87G@414999|Opitutae	414999|Opitutae	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
TH3_k127_5037113_19	497964.CfE428DRAFT_0492	1.696e-23	105.0	COG0091@1|root,COG0091@2|Bacteria,46T5F@74201|Verrucomicrobia	74201|Verrucomicrobia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
TH3_k127_5037113_6	452637.Oter_0220	5.641e-87	298.0	COG0092@1|root,COG0092@2|Bacteria,46SN9@74201|Verrucomicrobia,3K776@414999|Opitutae	414999|Opitutae	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
TH3_k127_5037113_11	497964.CfE428DRAFT_0494	4.228e-54	193.0	COG0197@1|root,COG0197@2|Bacteria,46ST6@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
TH3_k127_5037113_28	349741.Amuc_0295	0.0001941	51.0	COG0255@1|root,COG0255@2|Bacteria,46TAV@74201|Verrucomicrobia,2IUWM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal L29 protein	-	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
TH3_k127_5037113_18	1403819.BATR01000164_gene5565	1.51e-26	111.0	COG0186@1|root,COG0186@2|Bacteria,46T6M@74201|Verrucomicrobia,2IUPS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
TH3_k127_5037113_13	1156937.MFUM_870033	8.151e-47	171.0	COG0093@1|root,COG0093@2|Bacteria,46VID@74201|Verrucomicrobia,37GRN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
TH3_k127_5037113_20	382464.ABSI01000011_gene2659	3.926e-23	101.0	COG0198@1|root,COG0198@2|Bacteria,46T3M@74201|Verrucomicrobia,2IUUE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal proteins 50S L24/mitochondrial 39S L24	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
TH3_k127_5037113_9	635013.TherJR_0308	6.692e-60	212.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,2603I@186807|Peptococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
TH3_k127_5037113_17	1403819.BATR01000162_gene5349	2.62e-31	124.0	COG0199@1|root,COG0199@2|Bacteria,46TBH@74201|Verrucomicrobia,2IUM9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
TH3_k127_5037113_15	265311.Mfl137	3.903e-40	152.0	COG0096@1|root,COG0096@2|Bacteria,3WTD8@544448|Tenericutes	544448|Tenericutes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
TH3_k127_5037113_7	240016.ABIZ01000001_gene4064	9.286e-68	234.0	COG0097@1|root,COG0097@2|Bacteria,46SP9@74201|Verrucomicrobia,2IU69@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
TH3_k127_5037113_21	771875.Ferpe_1400	1.024e-20	94.0	COG0256@1|root,COG0256@2|Bacteria,2GD32@200918|Thermotogae	200918|Thermotogae	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
TH3_k127_5053679_4	102129.Lepto7375DRAFT_7777	5.792e-14	80.0	COG0457@1|root,COG0714@1|root,COG0457@2|Bacteria,COG0714@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
TH3_k127_5053679_1	497964.CfE428DRAFT_2487	1.442e-55	213.0	28HQ3@1|root,2Z7XW@2|Bacteria,46U81@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
TH3_k127_5053679_2	1231241.Mc24_08639	4.941e-50	195.0	COG0265@1|root,COG0265@2|Bacteria,2GCIH@200918|Thermotogae	200918|Thermotogae	M	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
TH3_k127_5053679_0	247490.KSU1_C0522	6.227e-94	317.0	COG1131@1|root,COG1131@2|Bacteria,2IX20@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_5053679_3	1192034.CAP_7501	4.721e-25	111.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,42SH9@68525|delta/epsilon subdivisions,2WPWW@28221|Deltaproteobacteria,2Z111@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
TH3_k127_505505_5	234267.Acid_3655	5.254e-09	61.0	COG0038@1|root,COG0457@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0457@2|Bacteria,COG0517@2|Bacteria,3Y2G4@57723|Acidobacteria	57723|Acidobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
TH3_k127_505505_0	864069.MicloDRAFT_00006680	6.798e-263	832.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2TVFI@28211|Alphaproteobacteria,1JXMK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Site-specific recombinase, DNA invertase Pin	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TH3_k127_505505_4	156889.Mmc1_1369	6.565e-14	72.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	2.7.7.49	ko:K00986,ko:K07497	-	-	-	-	ko00000,ko01000	-	-	-	HTH_32,rve,rve_3
TH3_k127_505505_2	394.NGR_c15980	9.381e-20	92.0	2EHAG@1|root,3394C@2|Bacteria,1NK4E@1224|Proteobacteria,2UJZB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Family of unknown function (DUF5372)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5372
TH3_k127_505505_1	522306.CAP2UW1_4279	1.115e-48	178.0	COG3415@1|root,COG3415@2|Bacteria,1RKUV@1224|Proteobacteria,2WFVI@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29
TH3_k127_507485_29	1408473.JHXO01000009_gene3340	7.5e-17	84.0	2DR6U@1|root,33AFB@2|Bacteria,4P5F6@976|Bacteroidetes,2FYZD@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_507485_7	1121403.AUCV01000020_gene3110	6.563e-120	395.0	COG1244@1|root,COG1244@2|Bacteria	2|Bacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	-
TH3_k127_507485_5	1340493.JNIF01000003_gene3969	3.918e-176	563.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TH3_k127_507485_0	452637.Oter_4336	7.164e-316	981.0	COG3534@1|root,COG3534@2|Bacteria,46UU3@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
TH3_k127_507485_31	1117319.PSPO_04042	5.709e-09	66.0	2BCPH@1|root,3269T@2|Bacteria,1RJN1@1224|Proteobacteria,1S744@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4824)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4824
TH3_k127_507485_15	338963.Pcar_1339	5.941e-70	251.0	28IWG@1|root,2Z8US@2|Bacteria,1NHDW@1224|Proteobacteria,42MHT@68525|delta/epsilon subdivisions,2WMMN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
TH3_k127_507485_28	1337936.IJ00_11875	1.768e-17	88.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,1GQ7T@1117|Cyanobacteria,1HJ6I@1161|Nostocales	1117|Cyanobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
TH3_k127_507485_13	644966.Tmar_2012	1.977e-84	287.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WCSJ@538999|Clostridiales incertae sedis	186801|Clostridia	P	Carbohydrate ABC transporter ATP-binding protein, CUT1 family	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
TH3_k127_507485_8	756272.Plabr_0071	8.445e-120	397.0	COG3635@1|root,COG3635@2|Bacteria,2IY5S@203682|Planctomycetes	203682|Planctomycetes	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
TH3_k127_507485_14	1499967.BAYZ01000097_gene4350	4.044e-81	291.0	COG4826@1|root,COG4826@2|Bacteria,2NQVB@2323|unclassified Bacteria	2|Bacteria	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
TH3_k127_507485_19	1191523.MROS_1767	4.331e-60	216.0	COG3298@1|root,COG3298@2|Bacteria	2|Bacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	wlaX	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
TH3_k127_507485_36	596328.HMPREF0578_1655	4.647e-05	53.0	COG0775@1|root,COG0775@2|Bacteria,2I8GZ@201174|Actinobacteria,4D3DV@85005|Actinomycetales	201174|Actinobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
TH3_k127_507485_17	497964.CfE428DRAFT_2670	8.939e-66	234.0	COG1562@1|root,COG1562@2|Bacteria,46TVP@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene/phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	Amino_oxidase,SQS_PSY
TH3_k127_507485_10	880072.Desac_0330	2.947e-113	384.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MR37@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TH3_k127_507485_25	269799.Gmet_2562	8.551e-30	136.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,43T97@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Nitrogen fixation master sensor histidine kinase, PAS domain-containing	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
TH3_k127_507485_16	240016.ABIZ01000001_gene2279	7.766e-70	241.0	COG0452@1|root,COG0452@2|Bacteria,46SPU@74201|Verrucomicrobia,2IUB8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Flavoprotein	-	-	4.1.1.36	ko:K01598	ko00770,ko01100,map00770,map01100	M00120	R03269	RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
TH3_k127_507485_22	583355.Caka_2132	1.881e-53	194.0	COG0194@1|root,COG0194@2|Bacteria,46SQG@74201|Verrucomicrobia,3K812@414999|Opitutae	414999|Opitutae	F	Guanylate kinase	-	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
TH3_k127_507485_12	497964.CfE428DRAFT_4161	1.473e-86	295.0	COG1561@1|root,COG1561@2|Bacteria,46TP9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
TH3_k127_507485_11	452637.Oter_4097	5.871e-112	374.0	COG0385@1|root,COG0385@2|Bacteria,46YMH@74201|Verrucomicrobia,3K9UA@414999|Opitutae	414999|Opitutae	S	Bile acid sodium symporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
TH3_k127_507485_39	1396141.BATP01000060_gene4559	0.0004003	48.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
TH3_k127_507485_9	1121904.ARBP01000042_gene4905	3.668e-115	400.0	COG3292@1|root,COG3292@2|Bacteria,4NF9I@976|Bacteroidetes,47XHD@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
TH3_k127_507485_20	984262.SGRA_1441	1.753e-59	218.0	COG0382@1|root,COG0382@2|Bacteria,4NEE3@976|Bacteroidetes,1IP3B@117747|Sphingobacteriia	976|Bacteroidetes	H	4-hydroxybenzoate polyprenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
TH3_k127_507485_18	497964.CfE428DRAFT_6143	3.106e-62	221.0	COG0163@1|root,COG0163@2|Bacteria,46V9E@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
TH3_k127_507485_23	497964.CfE428DRAFT_1387	3.445e-38	158.0	COG0860@1|root,COG0860@2|Bacteria,46SS7@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
TH3_k127_507485_37	481448.Minf_0708	5.983e-05	53.0	COG2242@1|root,COG2242@2|Bacteria,46WJ6@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
TH3_k127_507485_27	1035193.HMPREF9073_01297	8.616e-24	113.0	COG0463@1|root,COG0463@2|Bacteria,4P0ZE@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TH3_k127_507485_2	344747.PM8797T_29842	1.586e-205	660.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
TH3_k127_507485_4	1123508.JH636444_gene5476	1.968e-194	626.0	COG5316@1|root,COG5316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
TH3_k127_507485_21	485917.Phep_0675	3.732e-59	229.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,1IQSF@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
TH3_k127_507485_3	1121904.ARBP01000038_gene2566	2.234e-198	637.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,47JTA@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9
TH3_k127_507485_26	278957.ABEA03000095_gene4585	1.634e-24	104.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
TH3_k127_507485_24	232348.ADXL01000014_gene730	1.045e-30	123.0	COG4634@1|root,COG4634@2|Bacteria,1G6S3@1117|Cyanobacteria,1H23Q@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_507485_32	700598.Niako_6563	4.666e-08	56.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,1IQSF@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
TH3_k127_507485_34	1042377.AFPJ01000055_gene971	6.057e-07	59.0	COG1596@1|root,COG1596@2|Bacteria,1MXYS@1224|Proteobacteria,1S85D@1236|Gammaproteobacteria,468T5@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K20988	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
TH3_k127_507485_1	886293.Sinac_6122	2.145e-289	945.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
TH3_k127_507485_30	1396141.BATP01000007_gene5571	4.071e-16	94.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
TH3_k127_507485_33	497964.CfE428DRAFT_1412	3.635e-07	65.0	COG3250@1|root,COG4677@1|root,COG4932@1|root,COG3250@2|Bacteria,COG4677@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	3.1.1.11,3.2.1.55	ko:K01051,ko:K10297,ko:K20844	ko00040,ko00520,ko01100,map00040,map00520,map01100	M00081	R01762,R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000,ko04121	-	CBM42,GH54	-	AbfB,ArabFuran-catal,Beta_helix,Big_4,F5_F8_type_C,Glyco_hydr_30_2,Pectinesterase,RicinB_lectin_2
TH3_k127_507485_6	1340493.JNIF01000003_gene1832	3.861e-159	508.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
TH3_k127_507485_38	1403819.BATR01000153_gene5138	0.0001682	46.0	COG4948@1|root,COG4948@2|Bacteria,46S7G@74201|Verrucomicrobia,2IV9V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5076485_37	1313304.CALK_1499	6.639e-22	96.0	COG0363@1|root,COG0363@2|Bacteria	2|Bacteria	G	glucosamine-6-phosphate deaminase activity	nagB	GO:0003674,GO:0003824,GO:0004342,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0006044,GO:0006046,GO:0006047,GO:0006048,GO:0006054,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016054,GO:0016787,GO:0016853,GO:0016860,GO:0016861,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0019239,GO:0019262,GO:0019438,GO:0019752,GO:0034641,GO:0034654,GO:0042737,GO:0042802,GO:0043436,GO:0043877,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046348,GO:0046349,GO:0046395,GO:0046483,GO:0055086,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901362,GO:1901575,GO:1901576	3.1.1.31,3.5.99.6	ko:K01057,ko:K02080,ko:K02564	ko00030,ko00052,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00052,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035,R08365	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_02959,iECB_1328.ECB_03008,iECD_1391.ECD_03008,iECNA114_1301.ECNA114_3225,iECSF_1327.ECSF_2979,iYO844.BSU02360,iYO844.BSU35020,iZ_1308.Z0825	Glucosamine_iso,PIG-L
TH3_k127_5076485_22	1121957.ATVL01000014_gene1459	1.048e-75	273.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5076485_39	111780.Sta7437_3418	1.77e-18	89.0	COG1598@1|root,COG1598@2|Bacteria,1GAU7@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5076485_38	1173026.Glo7428_3849	1.182e-19	91.0	COG1724@1|root,COG1724@2|Bacteria,1G9Z7@1117|Cyanobacteria	1117|Cyanobacteria	N	PFAM YcfA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
TH3_k127_5076485_12	1340493.JNIF01000003_gene3009	3.164e-127	423.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Oxidoreduct_C,PmoA
TH3_k127_5076485_8	761193.Runsl_1895	8.395e-155	501.0	COG1520@1|root,COG1520@2|Bacteria,4NK4X@976|Bacteroidetes,47KWI@768503|Cytophagia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5076485_10	886293.Sinac_0668	1.342e-133	440.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TH3_k127_5076485_34	1123070.KB899247_gene1500	1.841e-31	127.0	2ERYI@1|root,33JHP@2|Bacteria,46WPE@74201|Verrucomicrobia,2IUEZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5076485_7	1403819.BATR01000094_gene2931	2.46e-160	512.0	COG1064@1|root,COG1064@2|Bacteria,46UV2@74201|Verrucomicrobia,2IVEY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
TH3_k127_5076485_6	1396418.BATQ01000041_gene6298	1.255e-167	543.0	COG0322@1|root,COG0322@2|Bacteria,46SAJ@74201|Verrucomicrobia,2IU0I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,UVR,UvrC_HhH_N
TH3_k127_5076485_20	497964.CfE428DRAFT_0066	4.502e-78	292.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
TH3_k127_5076485_36	1210884.HG799463_gene9871	8.686e-27	128.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_11,TPR_12,WD40
TH3_k127_5076485_4	1082933.MEA186_23031	3.341e-184	589.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.2,3.6.1.27	ko:K09474,ko:K19302	ko00550,ko00740,ko01100,ko02020,map00550,map00740,map01100,map02020	-	R00548,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
TH3_k127_5076485_28	349741.Amuc_1517	6.621e-49	182.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia,2IU42@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
TH3_k127_5076485_44	118168.MC7420_7676	6.279e-09	59.0	COG0493@1|root,COG0493@2|Bacteria,1G0SD@1117|Cyanobacteria,1H8CN@1150|Oscillatoriales	1117|Cyanobacteria	E	TIGRFAM glutamate synthases, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD	Fer4_20,Pyr_redox_2
TH3_k127_5076485_45	1379281.AVAG01000028_gene128	2.278e-07	55.0	COG1598@1|root,COG1598@2|Bacteria,1NPTZ@1224|Proteobacteria,431E8@68525|delta/epsilon subdivisions,2WWUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5076485_1	497965.Cyan7822_2990	1.042e-280	868.0	COG0493@1|root,COG0493@2|Bacteria,1G0SD@1117|Cyanobacteria,3KJF4@43988|Cyanothece	1117|Cyanobacteria	C	TIGRFAM glutamate synthase, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD	Fer4_20,Pyr_redox_2
TH3_k127_5076485_0	1173027.Mic7113_1425	0.0	2327.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1G0XM@1117|Cyanobacteria,1H9JF@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Conserved region in glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
TH3_k127_5076485_13	1156844.KB891831_gene4705	6.347e-119	399.0	COG0366@1|root,COG0366@2|Bacteria,2GN52@201174|Actinobacteria	201174|Actinobacteria	G	Alpha amylase catalytic	amyA	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
TH3_k127_5076485_29	497964.CfE428DRAFT_4835	1.991e-43	161.0	COG4747@1|root,COG4747@2|Bacteria,46WIS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT
TH3_k127_5076485_26	1051632.TPY_0383	7.052e-56	207.0	COG2912@1|root,COG2912@2|Bacteria,1VXJ8@1239|Firmicutes,25294@186801|Clostridia	186801|Clostridia	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
TH3_k127_5076485_19	1396418.BATQ01000136_gene3705	3.452e-91	314.0	COG1502@1|root,COG1502@2|Bacteria,46U9X@74201|Verrucomicrobia,2ITQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
TH3_k127_5076485_5	1396141.BATP01000003_gene5199	8.261e-171	546.0	COG1509@1|root,COG1509@2|Bacteria,46SVQ@74201|Verrucomicrobia,2ITNU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Lysine-2,3-aminomutase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,LAM_C,Radical_SAM
TH3_k127_5076485_35	497964.CfE428DRAFT_2283	4.239e-28	117.0	COG2331@1|root,COG2331@2|Bacteria,46T2S@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
TH3_k127_5076485_41	1210884.HG799464_gene10603	4.563e-14	85.0	2A5PP@1|root,30UEI@2|Bacteria,2J4IH@203682|Planctomycetes	1210884.HG799464_gene10603|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5076485_31	452637.Oter_2002	6.64e-42	159.0	COG2716@1|root,COG2716@2|Bacteria,46XGI@74201|Verrucomicrobia,3K9TK@414999|Opitutae	414999|Opitutae	E	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT_6
TH3_k127_5076485_9	1303518.CCALI_02044	9.187e-138	452.0	2EE91@1|root,3383F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5076485_21	886293.Sinac_0540	2.819e-76	261.0	COG0279@1|root,COG0279@2|Bacteria,2IZQU@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
TH3_k127_5076485_32	722419.PH505_co00060	3.864e-33	134.0	COG3296@1|root,COG3296@2|Bacteria,1RET3@1224|Proteobacteria,1S4H0@1236|Gammaproteobacteria,2Q2CW@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
TH3_k127_5076485_25	1123242.JH636434_gene4287	1.226e-58	233.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TH3_k127_5076485_18	1403819.BATR01000125_gene4449	2.365e-92	340.0	2CEMG@1|root,346QA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
TH3_k127_5076485_16	1121904.ARBP01000012_gene1301	1.381e-101	368.0	2DBK2@1|root,2Z9Q1@2|Bacteria,4NET4@976|Bacteroidetes,47MUQ@768503|Cytophagia	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5076485_30	1411123.JQNH01000001_gene687	2.623e-42	166.0	COG0382@1|root,COG0382@2|Bacteria,1RFNQ@1224|Proteobacteria,2U4XF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
TH3_k127_5076485_11	240016.ABIZ01000001_gene1581	5.469e-133	435.0	COG1082@1|root,COG1082@2|Bacteria,46UXT@74201|Verrucomicrobia,2ITIF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5076485_24	1235279.C772_01648	3.406e-68	241.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,26DBP@186818|Planococcaceae	91061|Bacilli	H	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
TH3_k127_5076485_40	344747.PM8797T_07909	2.216e-14	85.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_5076485_15	224911.27351242	8.846e-109	378.0	COG4191@1|root,COG4191@2|Bacteria,1NC2U@1224|Proteobacteria,2U484@28211|Alphaproteobacteria,3K3MC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,MASE3,Response_reg
TH3_k127_5076485_3	478741.JAFS01000002_gene302	1.27e-199	640.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,46TH0@74201|Verrucomicrobia,37G1H@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
TH3_k127_5076485_27	1519464.HY22_03120	4.451e-49	181.0	COG1335@1|root,COG1335@2|Bacteria,1FE0F@1090|Chlorobi	1090|Chlorobi	Q	PFAM isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
TH3_k127_5076485_23	521674.Plim_2940	1.118e-72	252.0	COG1387@1|root,COG1387@2|Bacteria,2IZCF@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_5076485_14	926550.CLDAP_33840	1.297e-110	366.0	COG1313@1|root,COG1313@2|Bacteria,2G65I@200795|Chloroflexi	200795|Chloroflexi	C	Radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
TH3_k127_5076485_2	595536.ADVE02000001_gene3060	3.236e-212	691.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,2TU4W@28211|Alphaproteobacteria,36Z5E@31993|Methylocystaceae	28211|Alphaproteobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
TH3_k127_5076485_17	1454004.AW11_00497	4.148e-93	316.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VKBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
TH3_k127_5076485_46	765913.ThidrDRAFT_2565	1.426e-06	51.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria,1WWGX@135613|Chromatiales	135613|Chromatiales	E	PFAM amino acid permease-associated region	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
TH3_k127_5076485_43	1247726.MIM_c11230	5.971e-10	63.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2VMP7@28216|Betaproteobacteria,3T3DK@506|Alcaligenaceae	28216|Betaproteobacteria	E	amino acid	steT	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
TH3_k127_507781_5	1499967.BAYZ01000119_gene3173	5.651e-53	194.0	28JE3@1|root,2Z98B@2|Bacteria,2NQ8M@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
TH3_k127_507781_6	383372.Rcas_1314	5.438e-20	91.0	2BRHQ@1|root,32KGQ@2|Bacteria,2GB33@200795|Chloroflexi,377U1@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_507781_7	1297865.APJD01000005_gene3689	8.097e-07	60.0	2BPPV@1|root,32IH2@2|Bacteria,1NFYU@1224|Proteobacteria,2UIKJ@28211|Alphaproteobacteria,3K4IG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_507781_0	1123242.JH636434_gene5489	1.518e-139	458.0	COG1070@1|root,COG1070@2|Bacteria,2IXYW@203682|Planctomycetes	203682|Planctomycetes	G	COG1070 Sugar (pentulose and hexulose)	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
TH3_k127_507781_2	575540.Isop_3679	4.507e-122	413.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.4	ko:K01132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00077,M00079	R07806	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
TH3_k127_507781_1	794903.OPIT5_18315	2.028e-129	438.0	COG0176@1|root,COG0176@2|Bacteria,46UAK@74201|Verrucomicrobia,3K7KW@414999|Opitutae	414999|Opitutae	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
TH3_k127_507781_4	1267535.KB906767_gene5199	1.329e-107	358.0	COG1082@1|root,COG1082@2|Bacteria,3Y78R@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_507781_3	382464.ABSI01000021_gene419	2.177e-109	358.0	COG0173@1|root,COG0173@2|Bacteria,46S7W@74201|Verrucomicrobia,2ITZA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
TH3_k127_5088985_5	481448.Minf_0381	3.595e-08	56.0	COG2121@1|root,COG2121@2|Bacteria,46SZ0@74201|Verrucomicrobia,37GQD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
TH3_k127_5088985_2	1403819.BATR01000092_gene2798	6.353e-33	147.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia,2IU0H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
TH3_k127_5088985_6	313628.LNTAR_23104	6.015e-08	63.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2
TH3_k127_5088985_1	153721.MYP_4858	4.494e-45	183.0	COG4733@1|root,COG4733@2|Bacteria,4NTXR@976|Bacteroidetes,47SSC@768503|Cytophagia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
TH3_k127_5088985_3	497964.CfE428DRAFT_4984	3.185e-24	119.0	COG1198@1|root,COG1198@2|Bacteria,46U3N@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
TH3_k127_5088985_0	686340.Metal_0565	6.17e-51	203.0	COG1002@1|root,COG1943@1|root,COG2890@1|root,COG1002@2|Bacteria,COG1943@2|Bacteria,COG2890@2|Bacteria,1RIWM@1224|Proteobacteria,1S7RK@1236|Gammaproteobacteria,1XFWD@135618|Methylococcales	135618|Methylococcales	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
TH3_k127_5088985_4	926550.CLDAP_04220	2.866e-11	77.0	COG1198@1|root,COG1198@2|Bacteria,2G60J@200795|Chloroflexi	200795|Chloroflexi	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
TH3_k127_5103019_1	1267535.KB906767_gene3746	1.022e-195	657.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,CBM-like,Glyco_hydro_38,Glyco_hydro_38C
TH3_k127_5103019_2	278957.ABEA03000005_gene4380	8.051e-170	542.0	COG0407@1|root,COG0407@2|Bacteria,46WW7@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
TH3_k127_5103019_0	1267533.KB906735_gene4670	3.52e-285	915.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
TH3_k127_5103019_8	1137269.AZWL01000013_gene2716	1.97e-24	121.0	COG3537@1|root,COG3537@2|Bacteria,2GKYM@201174|Actinobacteria	201174|Actinobacteria	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_92,NPCBM_assoc
TH3_k127_5103019_3	1192034.CAP_0893	1.594e-70	267.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
TH3_k127_5103019_4	1173028.ANKO01000062_gene2255	2.486e-52	210.0	COG2373@1|root,COG2931@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,1G02E@1117|Cyanobacteria,1H9TQ@1150|Oscillatoriales	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind
TH3_k127_5103019_9	864051.BurJ1DRAFT_0891	2.912e-11	79.0	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria,1R1VH@1224|Proteobacteria,2WI5Y@28216|Betaproteobacteria,1KP12@119065|unclassified Burkholderiales	2|Bacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,RCC1,RCC1_2,WD40
TH3_k127_5103019_7	1346330.M472_05315	8.483e-29	137.0	COG2911@1|root,COG3210@1|root,COG4932@1|root,COG5492@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,4NTNN@976|Bacteroidetes	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD
TH3_k127_5103019_5	1286631.X805_07670	6.072e-39	170.0	COG2304@1|root,COG2373@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VKA9@28216|Betaproteobacteria,1KK67@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	TIGRFAM outer membrane adhesin like proteiin	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,VWA_2
TH3_k127_5103019_6	1122917.KB899665_gene4007	1.811e-30	142.0	COG1572@1|root,COG2755@1|root,COG5434@1|root,COG5492@1|root,COG1572@2|Bacteria,COG2755@2|Bacteria,COG5434@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	xynX3	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,DUF1735,Flg_new,Laminin_G_3,Lipase_GDSL_2,PrcB_C,SLH
TH3_k127_5124110_5	760568.Desku_0794	1.568e-39	157.0	COG3547@1|root,COG3547@2|Bacteria,1V0B6@1239|Firmicutes,248VY@186801|Clostridia,264BH@186807|Peptococcaceae	186801|Clostridia	L	PFAM Transposase, IS111A IS1328 IS1533	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
TH3_k127_5124110_7	710696.Intca_0033	9.776e-12	71.0	COG3547@1|root,COG3547@2|Bacteria,2GNQB@201174|Actinobacteria,4FG97@85021|Intrasporangiaceae	201174|Actinobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
TH3_k127_5124110_1	330214.NIDE0545	3.293e-60	239.0	COG0745@1|root,COG2202@1|root,COG3290@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GGDEF,HATPase_c,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SpoIIE,dCache_1
TH3_k127_5124110_4	1121456.ATVA01000011_gene1415	7.192e-41	176.0	COG2972@1|root,COG4585@1|root,COG2972@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42SJA@68525|delta/epsilon subdivisions,2WPP4@28221|Deltaproteobacteria,2MG1K@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3,PAS,PAS_4,PAS_8,PAS_9,Response_reg
TH3_k127_5124110_3	909663.KI867150_gene1086	4.185e-52	192.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42N8J@68525|delta/epsilon subdivisions,2WK63@28221|Deltaproteobacteria,2MRGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_5124110_6	1123242.JH636434_gene5272	6.69e-15	78.0	COG1621@1|root,COG1621@2|Bacteria,2IY26@203682|Planctomycetes	2|Bacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,HTH_18,RicinB_lectin_2
TH3_k127_5124110_2	240016.ABIZ01000001_gene3538	3.851e-57	225.0	COG2755@1|root,COG2755@2|Bacteria,46WAY@74201|Verrucomicrobia	74201|Verrucomicrobia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5124110_0	1203550.HMPREF1475_00695	1.024e-101	361.0	COG3533@1|root,COG3533@2|Bacteria,4NG7T@976|Bacteroidetes,2FPXE@200643|Bacteroidia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
TH3_k127_5139584_1	1210884.HG799464_gene10819	3.872e-137	441.0	COG1233@1|root,COG1233@2|Bacteria,2IYJC@203682|Planctomycetes	203682|Planctomycetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
TH3_k127_5139584_6	278957.ABEA03000041_gene2243	1.227e-24	104.0	COG3727@1|root,COG3727@2|Bacteria,46VQU@74201|Verrucomicrobia,3K8JQ@414999|Opitutae	414999|Opitutae	L	DNA mismatch endonuclease Vsr	-	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
TH3_k127_5139584_10	1123366.TH3_03429	2.492e-17	87.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2U7H5@28211|Alphaproteobacteria,2JTP4@204441|Rhodospirillales	204441|Rhodospirillales	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
TH3_k127_5139584_8	1335757.SPICUR_03845	3.463e-24	108.0	COG2199@1|root,COG3852@1|root,COG3706@2|Bacteria,COG3852@2|Bacteria,1R7HC@1224|Proteobacteria,1RZKN@1236|Gammaproteobacteria,1X0QN@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_9
TH3_k127_5139584_11	1123242.JH636438_gene5714	0.000683	47.0	COG4276@1|root,COG4276@2|Bacteria,2J0FI@203682|Planctomycetes	203682|Planctomycetes	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
TH3_k127_5139584_2	452637.Oter_1107	8.784e-105	349.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,46V45@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
TH3_k127_5139584_4	452637.Oter_1108	1.536e-56	203.0	COG2335@1|root,COG2335@2|Bacteria,46VJN@74201|Verrucomicrobia,3K9JN@414999|Opitutae	414999|Opitutae	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
TH3_k127_5139584_3	240015.ACP_1727	7.219e-59	209.0	COG1028@1|root,COG1028@2|Bacteria	240015.ACP_1727|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5139584_9	755178.Cyan10605_1738	2.633e-23	106.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,Response_reg
TH3_k127_5139584_0	1123242.JH636434_gene5621	5.239e-188	599.0	COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
TH3_k127_5139584_5	452637.Oter_1109	1.2e-47	177.0	COG4276@1|root,COG4276@2|Bacteria,46X6Q@74201|Verrucomicrobia,3K9Y1@414999|Opitutae	414999|Opitutae	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5139584_7	794903.OPIT5_07690	2.598e-24	115.0	COG3170@1|root,COG3170@2|Bacteria,46Y8C@74201|Verrucomicrobia,3K93X@414999|Opitutae	414999|Opitutae	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5160309_1	886293.Sinac_6992	2.573e-87	297.0	COG4806@1|root,COG4806@2|Bacteria,2IXTQ@203682|Planctomycetes	203682|Planctomycetes	G	L-rhamnose isomerase	rhaA	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
TH3_k127_5160309_3	1121481.AUAS01000002_gene3607	4.435e-11	67.0	COG0221@1|root,COG0221@2|Bacteria,4PBT1@976|Bacteroidetes,47WA3@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5160309_0	761193.Runsl_3310	1.673e-133	443.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_5160309_2	497964.CfE428DRAFT_4312	8.194e-45	168.0	COG1994@1|root,COG1994@2|Bacteria,46VEB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50,Peptidase_M50B
TH3_k127_5162823_4	497964.CfE428DRAFT_3346	2.046e-175	557.0	COG0520@1|root,COG0520@2|Bacteria,46S58@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
TH3_k127_5162823_16	118005.AWNK01000005_gene1565	2.476e-46	177.0	COG0290@1|root,COG0290@2|Bacteria	2|Bacteria	J	translation initiation factor activity	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
TH3_k127_5162823_5	452637.Oter_0886	8.855e-139	449.0	COG0468@1|root,COG0468@2|Bacteria,46SIZ@74201|Verrucomicrobia,3K737@414999|Opitutae	414999|Opitutae	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
TH3_k127_5162823_6	278963.ATWD01000002_gene473	1.079e-121	402.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	mdsC	-	2.7.1.162,2.7.1.39	ko:K02204,ko:K13059	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771,R08962	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
TH3_k127_5162823_25	1121887.AUDK01000004_gene431	6.105e-06	61.0	COG2911@1|root,COG3210@1|root,COG3533@1|root,COG4625@1|root,COG4733@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3533@2|Bacteria,COG4625@2|Bacteria,COG4733@2|Bacteria,4PPKP@976|Bacteroidetes,1IKQ3@117743|Flavobacteriia,2P0T3@237|Flavobacterium	976|Bacteroidetes	U	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Laminin_G_3
TH3_k127_5162823_12	28072.Nos7524_1372	2.039e-64	253.0	COG1572@1|root,COG2931@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1G1WI@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Bacterial pre-peptidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cadherin,Calx-beta,PPC
TH3_k127_5162823_2	880073.Calab_3105	2.647e-230	728.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	BT1,MFS_1
TH3_k127_5162823_7	234267.Acid_1881	1.072e-115	379.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_5162823_11	234267.Acid_1882	9.736e-77	265.0	2DF1J@1|root,2ZQ4G@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
TH3_k127_5162823_24	880073.Calab_3105	6.101e-07	62.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	BT1,MFS_1
TH3_k127_5162823_23	1121939.L861_16535	2.945e-10	62.0	COG2331@1|root,COG2331@2|Bacteria,1NMRY@1224|Proteobacteria	1224|Proteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
TH3_k127_5162823_15	1123368.AUIS01000029_gene1290	3.952e-49	182.0	COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,1S4E9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	NMD3
TH3_k127_5162823_19	296591.Bpro_3359	4.459e-33	133.0	COG0527@1|root,COG0527@2|Bacteria,1REUY@1224|Proteobacteria,2VS69@28216|Betaproteobacteria	28216|Betaproteobacteria	E	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT,ACT_6
TH3_k127_5162823_10	909663.KI867150_gene1088	1.387e-90	303.0	COG1394@1|root,COG1394@2|Bacteria,1PA1A@1224|Proteobacteria,42VQ3@68525|delta/epsilon subdivisions,2WT1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
TH3_k127_5162823_1	909663.KI867150_gene1089	8.847e-273	845.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,42PJC@68525|delta/epsilon subdivisions,2WJB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
TH3_k127_5162823_0	909663.KI867150_gene1090	0.0	1016.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,42NKK@68525|delta/epsilon subdivisions,2WIQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
TH3_k127_5162823_13	909663.KI867150_gene1091	6.626e-60	215.0	2FA6P@1|root,342FE@2|Bacteria	2|Bacteria	S	ATP synthase (E/31 kDa) subunit	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
TH3_k127_5162823_18	909663.KI867150_gene1092	1.125e-36	140.0	COG1436@1|root,COG1436@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
TH3_k127_5162823_20	909663.KI867150_gene1093	7.187e-31	125.0	COG0636@1|root,COG0636@2|Bacteria,1NG0V@1224|Proteobacteria,42XT7@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
TH3_k127_5162823_17	452637.Oter_1848	1.149e-37	145.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TH3_k127_5162823_3	909663.KI867150_gene1094	4.934e-230	729.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42SY2@68525|delta/epsilon subdivisions,2X5C4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	V-type ATPase 116kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
TH3_k127_5162823_9	909663.KI867150_gene1095	6.217e-108	360.0	COG1527@1|root,COG1527@2|Bacteria	2|Bacteria	C	subunit (C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
TH3_k127_5162823_21	909663.KI867150_gene1096	3.095e-19	93.0	294CD@1|root,2ZRSF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5162823_14	945713.IALB_0431	1.146e-52	194.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
TH3_k127_5162823_8	497964.CfE428DRAFT_1398	1.804e-114	378.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46U11@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TH3_k127_5167728_11	1123405.AUMM01000031_gene1488	4.249e-05	47.0	2DTS4@1|root,33MFD@2|Bacteria,1VKHK@1239|Firmicutes,4I120@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5167728_6	933262.AXAM01000042_gene1817	4.387e-27	124.0	COG1555@1|root,COG3156@1|root,COG1555@2|Bacteria,COG3156@2|Bacteria,1PQMW@1224|Proteobacteria,42T9B@68525|delta/epsilon subdivisions,2WPYT@28221|Deltaproteobacteria,2MKAN@213118|Desulfobacterales	28221|Deltaproteobacteria	LU	Type II secretion system (T2SS), protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
TH3_k127_5167728_9	1385517.N800_00590	6.5e-08	63.0	COG4795@1|root,COG4795@2|Bacteria,1MYPS@1224|Proteobacteria,1SHGQ@1236|Gammaproteobacteria,1X6ZS@135614|Xanthomonadales	135614|Xanthomonadales	U	General secretion pathway protein	xpsJ	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_5167728_13	1144342.PMI40_00304	0.0002146	51.0	COG4970@1|root,COG4970@2|Bacteria,1NGHS@1224|Proteobacteria,2WCQV@28216|Betaproteobacteria,474MH@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Type II transport protein GspH	fimT	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
TH3_k127_5167728_4	1297742.A176_06707	7.961e-73	261.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
TH3_k127_5167728_3	485913.Krac_6839	6.564e-74	259.0	COG1606@1|root,COG1606@2|Bacteria,2G6AU@200795|Chloroflexi	200795|Chloroflexi	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
TH3_k127_5167728_2	385682.AFSL01000012_gene2848	5.525e-124	418.0	COG3401@1|root,COG3401@2|Bacteria,4NFM5@976|Bacteroidetes,2FPSM@200643|Bacteroidia	976|Bacteroidetes	S	candidate rhamnogalacturonan lyase, polysaccharide lyase family 11 protein K01238	-	-	4.2.2.23	ko:K18197	-	-	-	-	ko00000,ko01000	-	PL11	-	-
TH3_k127_5167728_1	266265.Bxe_B2149	2.491e-191	612.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria,1JZMS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3,1.2.1.39,1.2.1.8	ko:K00128,ko:K00130,ko:K00146	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TH3_k127_5167728_0	234267.Acid_4168	6.226e-193	617.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TH3_k127_5167728_10	497964.CfE428DRAFT_3301	1.155e-07	56.0	COG0422@1|root,COG0422@2|Bacteria,46S5R@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
TH3_k127_5167728_7	592015.HMPREF1705_01630	9.338e-27	111.0	COG2026@1|root,COG2026@2|Bacteria,3TCJI@508458|Synergistetes	508458|Synergistetes	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
TH3_k127_5167728_8	592015.HMPREF1705_01629	1.204e-09	62.0	2CD07@1|root,2ZQEB@2|Bacteria	2|Bacteria	S	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
TH3_k127_5167728_5	234267.Acid_4169	3.275e-43	161.0	COG5000@1|root,COG5000@2|Bacteria,3Y2TD@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
TH3_k127_5174191_1	497964.CfE428DRAFT_3809	3.495e-61	222.0	COG0330@1|root,COG0330@2|Bacteria,46VZD@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TH3_k127_5174191_4	1196083.SALWKB12_1701	7.373e-15	85.0	COG3012@1|root,COG3012@2|Bacteria,1NGS9@1224|Proteobacteria	1224|Proteobacteria	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
TH3_k127_5174191_3	671143.DAMO_2920	3.579e-27	118.0	2DRSH@1|root,33CVS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5174191_2	1242864.D187_010252	1.033e-51	188.0	COG0476@1|root,COG0476@2|Bacteria,1Q38H@1224|Proteobacteria,438ZG@68525|delta/epsilon subdivisions,2X44R@28221|Deltaproteobacteria,2YY93@29|Myxococcales	28221|Deltaproteobacteria	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
TH3_k127_5174191_0	497964.CfE428DRAFT_5203	4.285e-97	322.0	COG3344@1|root,COG3344@2|Bacteria,46SUD@74201|Verrucomicrobia	2|Bacteria	L	Group II intron maturase-specific domain protein	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
TH3_k127_5225430_16	344747.PM8797T_21498	5.969e-105	361.0	COG0515@1|root,COG0515@2|Bacteria,2IXG3@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	HDOD,Pkinase,dCache_1
TH3_k127_5225430_20	485913.Krac_10089	4.186e-80	274.0	COG2326@1|root,COG2326@2|Bacteria,2G5UP@200795|Chloroflexi	200795|Chloroflexi	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
TH3_k127_5225430_22	546266.NEIMUCOT_06302	5.606e-68	244.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria,2KQN6@206351|Neisseriales	206351|Neisseriales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
TH3_k127_5225430_5	1396141.BATP01000020_gene50	3.2e-212	702.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
TH3_k127_5225430_6	243231.GSU3381	1.827e-182	607.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,43TFF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
TH3_k127_5225430_4	1123070.KB899248_gene60	4.359e-215	676.0	COG0017@1|root,COG0017@2|Bacteria,46TN6@74201|Verrucomicrobia,2ITHF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
TH3_k127_5225430_2	497964.CfE428DRAFT_3579	1.167e-235	754.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
TH3_k127_5225430_3	497964.CfE428DRAFT_3580	9.527e-235	734.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TH3_k127_5225430_25	497964.CfE428DRAFT_5946	4.243e-41	161.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_5225430_9	243233.MCA2756	2.24e-156	501.0	COG0438@1|root,COG0438@2|Bacteria,1NMB5@1224|Proteobacteria,1RRVU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Sulfotransfer_3
TH3_k127_5225430_23	1304275.C41B8_01647	7.273e-65	229.0	COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25,2.7.7.4	ko:K00860,ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
TH3_k127_5225430_12	497964.CfE428DRAFT_1935	9.381e-130	422.0	COG2870@1|root,COG2870@2|Bacteria	2|Bacteria	H	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,Hydrolase,PfkB
TH3_k127_5225430_11	1123242.JH636434_gene3161	4.268e-151	486.0	COG1915@1|root,COG1915@2|Bacteria,2IXX9@203682|Planctomycetes	203682|Planctomycetes	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5225430_21	1499967.BAYZ01000068_gene1935	1.087e-69	272.0	COG3266@1|root,COG3420@1|root,COG4733@1|root,COG3266@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,2NS5M@2323|unclassified Bacteria	2|Bacteria	P	Fibronectin type 3 domain	-	-	-	ko:K12685,ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CHB_HEX_C_1,CHU_C,DUF1573,DUF285,F5_F8_type_C,Laminin_G_3,Lectin_legB,fn3
TH3_k127_5225430_28	1123277.KB893172_gene995	2.126e-32	149.0	COG1520@1|root,COG3210@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K02406,ko:K21449	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02000,ko02035	1.B.40.2	-	-	Beta_helix,DUF5122
TH3_k127_5225430_24	765420.OSCT_3130	7.545e-47	196.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
TH3_k127_5225430_0	1173024.KI912153_gene216	0.0	1675.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1G2E2@1117|Cyanobacteria,1JKG2@1189|Stigonemataceae	1117|Cyanobacteria	C	Domain of unknown function	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
TH3_k127_5225430_10	1173024.KI912153_gene217	1.875e-153	490.0	COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1JKMZ@1189|Stigonemataceae	1117|Cyanobacteria	F	Dihydroorotate dehydrogenase	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
TH3_k127_5225430_19	909663.KI867150_gene2007	7.912e-84	294.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MR82@213462|Syntrophobacterales	28221|Deltaproteobacteria	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
TH3_k127_5225430_1	765952.PUV_14580	2.317e-302	939.0	COG0365@1|root,COG0365@2|Bacteria,2JFRM@204428|Chlamydiae	204428|Chlamydiae	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
TH3_k127_5225430_7	497964.CfE428DRAFT_0827	3.801e-174	557.0	COG2223@1|root,COG2223@2|Bacteria,46UH2@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TH3_k127_5225430_15	497964.CfE428DRAFT_1406	6.478e-106	366.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,46S8W@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM CBS domain containing protein	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
TH3_k127_5225430_8	794903.OPIT5_19015	1.595e-161	525.0	COG0143@1|root,COG0143@2|Bacteria,46SCQ@74201|Verrucomicrobia,3K783@414999|Opitutae	414999|Opitutae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
TH3_k127_5225430_31	497964.CfE428DRAFT_4116	5.587e-16	87.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TH3_k127_5225430_32	102125.Xen7305DRAFT_00008790	4.08e-08	59.0	2CRRJ@1|root,32SPH@2|Bacteria,1GGJ1@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
TH3_k127_5225430_30	215803.DB30_7168	3.327e-17	93.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
TH3_k127_5225430_13	429009.Adeg_1724	2.547e-123	405.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,42F4T@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
TH3_k127_5225430_17	404589.Anae109_3433	3.205e-99	337.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
TH3_k127_5225430_29	1123401.JHYQ01000006_gene6	2.961e-29	126.0	COG1432@1|root,COG1432@2|Bacteria,1REF0@1224|Proteobacteria,1S545@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	NYN
TH3_k127_5225430_14	696747.NIES39_E02730	5.309e-114	386.0	COG0745@1|root,COG2114@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1HHU4@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1
TH3_k127_5225430_27	278957.ABEA03000035_gene748	1.125e-34	137.0	COG0745@1|root,COG0745@2|Bacteria,46V0J@74201|Verrucomicrobia,3K7HQ@414999|Opitutae	414999|Opitutae	T	PFAM response regulator receiver	-	-	2.7.7.65	ko:K02488,ko:K02658	ko02020,ko02025,ko04112,map02020,map02025,map04112	M00507,M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko02044	-	-	-	Response_reg
TH3_k127_5225430_18	166318.Syn8016DRAFT_1993	5.043e-98	329.0	COG2201@1|root,COG2201@2|Bacteria,1GJ7G@1117|Cyanobacteria,1H1FB@1129|Synechococcus	1117|Cyanobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
TH3_k127_5261225_34	244447.XP_008310645.1	1.586e-12	81.0	28K45@1|root,2QSIP@2759|Eukaryota,38E3S@33154|Opisthokonta,3BBJ0@33208|Metazoa,3CSD9@33213|Bilateria,4896I@7711|Chordata,48YCX@7742|Vertebrata,49W5A@7898|Actinopterygii	33208|Metazoa	T	Reelin-like	RELN	GO:0000902,GO:0000904,GO:0001101,GO:0001764,GO:0001932,GO:0001934,GO:0001941,GO:0003002,GO:0003008,GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006935,GO:0006950,GO:0006996,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007389,GO:0007399,GO:0007409,GO:0007411,GO:0007416,GO:0007417,GO:0007420,GO:0007494,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007616,GO:0007626,GO:0008104,GO:0008150,GO:0008152,GO:0008306,GO:0008347,GO:0009410,GO:0009605,GO:0009611,GO:0009612,GO:0009628,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009889,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010001,GO:0010033,GO:0010035,GO:0010038,GO:0010226,GO:0010243,GO:0010468,GO:0010469,GO:0010556,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010720,GO:0010769,GO:0010770,GO:0010975,GO:0010976,GO:0014066,GO:0014068,GO:0014070,GO:0016043,GO:0016310,GO:0016358,GO:0016477,GO:0017085,GO:0018108,GO:0018193,GO:0018212,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0021510,GO:0021511,GO:0021517,GO:0021536,GO:0021537,GO:0021542,GO:0021543,GO:0021761,GO:0021766,GO:0021769,GO:0021795,GO:0021799,GO:0021800,GO:0021801,GO:0021819,GO:0021854,GO:0021885,GO:0021987,GO:0022008,GO:0022029,GO:0022030,GO:0022603,GO:0022604,GO:0022607,GO:0022898,GO:0023051,GO:0023052,GO:0023056,GO:0030030,GO:0030154,GO:0030182,GO:0030334,GO:0030335,GO:0030424,GO:0030425,GO:0030900,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031326,GO:0031344,GO:0031346,GO:0031399,GO:0031401,GO:0031503,GO:0031644,GO:0031646,GO:0031960,GO:0032006,GO:0032008,GO:0032268,GO:0032270,GO:0032409,GO:0032411,GO:0032412,GO:0032414,GO:0032501,GO:0032502,GO:0032570,GO:0032793,GO:0032870,GO:0032879,GO:0032989,GO:0032990,GO:0033036,GO:0033555,GO:0033674,GO:0033993,GO:0034613,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0035176,GO:0035295,GO:0035418,GO:0035690,GO:0036211,GO:0036477,GO:0038026,GO:0040011,GO:0040012,GO:0040017,GO:0042063,GO:0042221,GO:0042325,GO:0042327,GO:0042330,GO:0042391,GO:0042493,GO:0042995,GO:0043005,GO:0043025,GO:0043085,GO:0043113,GO:0043170,GO:0043200,GO:0043204,GO:0043269,GO:0043270,GO:0043412,GO:0043549,GO:0044057,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044297,GO:0044421,GO:0044424,GO:0044463,GO:0044464,GO:0045471,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045859,GO:0045860,GO:0045937,GO:0046677,GO:0048167,GO:0048265,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048565,GO:0048583,GO:0048584,GO:0048646,GO:0048666,GO:0048667,GO:0048678,GO:0048699,GO:0048731,GO:0048812,GO:0048814,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050730,GO:0050731,GO:0050767,GO:0050769,GO:0050773,GO:0050775,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050795,GO:0050803,GO:0050804,GO:0050806,GO:0050807,GO:0050808,GO:0050877,GO:0050890,GO:0050896,GO:0051049,GO:0051050,GO:0051056,GO:0051057,GO:0051090,GO:0051091,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051270,GO:0051272,GO:0051338,GO:0051347,GO:0051384,GO:0051385,GO:0051412,GO:0051602,GO:0051641,GO:0051668,GO:0051674,GO:0051703,GO:0051704,GO:0051705,GO:0051716,GO:0051960,GO:0051962,GO:0051966,GO:0051968,GO:0055123,GO:0060255,GO:0060284,GO:0060291,GO:0060322,GO:0060998,GO:0060999,GO:0061001,GO:0061003,GO:0061024,GO:0061097,GO:0061098,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070325,GO:0070326,GO:0070542,GO:0070727,GO:0070887,GO:0070925,GO:0071310,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072578,GO:0072657,GO:0080090,GO:0090128,GO:0090129,GO:0097106,GO:0097107,GO:0097114,GO:0097119,GO:0097120,GO:0097305,GO:0097327,GO:0097447,GO:0097458,GO:0097475,GO:0097476,GO:0097477,GO:0097485,GO:0098698,GO:0098815,GO:0099068,GO:0099084,GO:0099173,GO:0099175,GO:0099177,GO:0099601,GO:0120025,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:1900006,GO:1900271,GO:1900273,GO:1900449,GO:1900451,GO:1901564,GO:1901654,GO:1901655,GO:1901698,GO:1901700,GO:1901701,GO:1902076,GO:1902078,GO:1902531,GO:1902533,GO:1903506,GO:1904062,GO:1904064,GO:1904861,GO:1905483,GO:1905485,GO:2000026,GO:2000112,GO:2000145,GO:2000147,GO:2000273,GO:2000310,GO:2000311,GO:2000463,GO:2000969,GO:2001141,GO:2001222,GO:2001224,GO:2001257,GO:2001259	-	ko:K06249	ko04151,ko04510,ko04512,ko05165,map04151,map04510,map04512,map05165	-	-	-	ko00000,ko00001,ko01000,ko04516	-	-	-	EGF_2,Reeler
TH3_k127_5261225_23	1396141.BATP01000056_gene3278	1.241e-46	193.0	COG0028@1|root,COG3055@1|root,COG3209@1|root,COG4625@1|root,COG4932@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	4.1.3.1	ko:K01637,ko:K20276	ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	He_PIG,Laminin_G_3,Malectin
TH3_k127_5261225_30	237368.SCABRO_00978	2.114e-28	134.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	BACON,DUF11,Fil_haemagg_2,Flg_new,PATR
TH3_k127_5261225_29	640511.BC1002_3648	4.513e-30	131.0	COG0500@1|root,COG2226@2|Bacteria,1PI8I@1224|Proteobacteria,2W6W0@28216|Betaproteobacteria,1KCXH@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TH3_k127_5261225_27	759914.BP951000_2310	8.679e-31	141.0	COG4485@1|root,COG5617@1|root,COG4485@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
TH3_k127_5261225_2	240016.ABIZ01000001_gene1604	1.726e-233	736.0	COG0423@1|root,COG0423@2|Bacteria,46TEV@74201|Verrucomicrobia,2ITMG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Anticodon binding domain	-	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
TH3_k127_5261225_28	1038869.AXAN01000002_gene225	4.06e-30	132.0	COG0628@1|root,COG0628@2|Bacteria,1MW34@1224|Proteobacteria,2VIKI@28216|Betaproteobacteria,1K0I9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TH3_k127_5261225_17	1125863.JAFN01000001_gene1724	1.516e-63	228.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
TH3_k127_5261225_5	497964.CfE428DRAFT_1506	1.42e-147	478.0	COG0766@1|root,COG0766@2|Bacteria,46S6Q@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
TH3_k127_5261225_0	1396418.BATQ01000109_gene4735	2.851e-265	852.0	COG0060@1|root,COG0060@2|Bacteria,46SEC@74201|Verrucomicrobia,2ITJZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
TH3_k127_5261225_11	452637.Oter_3564	5.363e-86	300.0	COG2518@1|root,COG2518@2|Bacteria,46UEK@74201|Verrucomicrobia,3K7SY@414999|Opitutae	414999|Opitutae	O	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
TH3_k127_5261225_31	574087.Acear_2177	7.724e-28	127.0	COG0795@1|root,COG0795@2|Bacteria,1TRZG@1239|Firmicutes,24CCP@186801|Clostridia,3WAFW@53433|Halanaerobiales	186801|Clostridia	S	Permease YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
TH3_k127_5261225_8	1156937.MFUM_230006	1.251e-119	405.0	COG1956@1|root,COG2203@1|root,COG4191@1|root,COG1956@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,46SAZ@74201|Verrucomicrobia,37G69@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
TH3_k127_5261225_24	497964.CfE428DRAFT_0221	9.381e-40	155.0	2EKW2@1|root,33EJK@2|Bacteria,46VZV@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5261225_18	1403819.BATR01000031_gene1028	6.313e-61	218.0	COG0571@1|root,COG0571@2|Bacteria,46T3X@74201|Verrucomicrobia,2IU7S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
TH3_k127_5261225_4	1031288.AXAA01000009_gene666	7.818e-168	548.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,36DCW@31979|Clostridiaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
TH3_k127_5261225_10	497964.CfE428DRAFT_4748	8.159e-97	323.0	COG1208@1|root,COG1208@2|Bacteria,46V3X@74201|Verrucomicrobia	74201|Verrucomicrobia	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TH3_k127_5261225_1	452637.Oter_3558	3.615e-250	779.0	COG1032@1|root,COG1032@2|Bacteria,46V7P@74201|Verrucomicrobia,3K74V@414999|Opitutae	414999|Opitutae	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
TH3_k127_5261225_3	1403819.BATR01000125_gene4494	8.307e-181	604.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia,2IV8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
TH3_k127_5261225_21	1396141.BATP01000002_gene4845	9.621e-54	196.0	COG2197@1|root,COG2197@2|Bacteria,46TQM@74201|Verrucomicrobia,2IVME@203494|Verrucomicrobiae	2|Bacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_5261225_12	794903.OPIT5_24610	4.363e-82	286.0	COG0657@1|root,COG0657@2|Bacteria,46UVS@74201|Verrucomicrobia	2|Bacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
TH3_k127_5261225_32	794903.OPIT5_12525	3.03e-20	100.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_5261225_20	485917.Phep_1293	4.124e-57	224.0	2C4R9@1|root,32RED@2|Bacteria,4P0US@976|Bacteroidetes	976|Bacteroidetes	S	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
TH3_k127_5261225_33	566466.NOR53_2254	8.73e-13	79.0	COG2304@1|root,COG2931@1|root,COG3209@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1J94H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	MQ	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,He_PIG,HemolysinCabind,VWA_2
TH3_k127_5261225_16	497964.CfE428DRAFT_4056	4.844e-67	235.0	COG2755@1|root,COG2755@2|Bacteria,46T12@74201|Verrucomicrobia	74201|Verrucomicrobia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TH3_k127_5261225_26	143224.JQMD01000002_gene4173	2.88e-34	137.0	COG2755@1|root,COG2755@2|Bacteria,4NQAK@976|Bacteroidetes,1I340@117743|Flavobacteriia	976|Bacteroidetes	E	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
TH3_k127_5261225_6	266117.Rxyl_3138	5.033e-140	454.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria	84995|Rubrobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TH3_k127_5261225_36	1173023.KE650771_gene983	0.0001803	47.0	COG0457@1|root,COG0457@2|Bacteria,1G31A@1117|Cyanobacteria,1JK03@1189|Stigonemataceae	1117|Cyanobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
TH3_k127_5261225_7	472759.Nhal_1554	1.402e-139	458.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria,1X0HU@135613|Chromatiales	135613|Chromatiales	S	PFAM Tetratricopeptide TPR_4	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5261225_15	221288.JH992901_gene3760	3.405e-68	237.0	COG1247@1|root,COG1247@2|Bacteria,1G8E2@1117|Cyanobacteria	1117|Cyanobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
TH3_k127_5261225_14	497964.CfE428DRAFT_4864	3.994e-78	270.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5261225_35	596152.DesU5LDRAFT_2094	2.378e-07	63.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WIYD@28221|Deltaproteobacteria,2M82M@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TH3_k127_5261225_9	497964.CfE428DRAFT_4863	3.322e-106	386.0	COG0515@1|root,COG0515@2|Bacteria	497964.CfE428DRAFT_4863|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5261225_19	1210884.HG799476_gene15380	2.965e-57	229.0	COG1595@1|root,COG1595@2|Bacteria,2IZH8@203682|Planctomycetes	203682|Planctomycetes	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_2
TH3_k127_5261225_25	886293.Sinac_0185	3.13e-36	160.0	COG1595@1|root,COG1595@2|Bacteria,2IZH8@203682|Planctomycetes	203682|Planctomycetes	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_2
TH3_k127_5261225_13	794903.OPIT5_20525	1.199e-80	275.0	COG1943@1|root,COG1943@2|Bacteria,46XEX@74201|Verrucomicrobia,3K9MH@414999|Opitutae	414999|Opitutae	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	-
TH3_k127_5271653_2	382464.ABSI01000010_gene3676	1.103e-59	211.0	COG2204@1|root,COG2204@2|Bacteria,46SDB@74201|Verrucomicrobia,2IU0F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
TH3_k127_5271653_0	1396418.BATQ01000091_gene5765	1.431e-124	415.0	COG0617@1|root,COG0617@2|Bacteria,46S8B@74201|Verrucomicrobia,2ITTG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Poly A polymerase head domain	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
TH3_k127_5271653_1	497964.CfE428DRAFT_1667	6.254e-75	262.0	COG1082@1|root,COG1082@2|Bacteria,46SWH@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_5271653_3	452637.Oter_2093	2.093e-12	68.0	COG0828@1|root,COG0828@2|Bacteria,46WBR@74201|Verrucomicrobia,3K8F7@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
TH3_k127_5271653_5	1347086.CCBA010000012_gene2030	0.0004512	44.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5271653_4	388051.AUFE01000129_gene4953	4.673e-06	49.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,1K2WH@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Elements of external origin	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23
TH3_k127_5273323_1	556261.HMPREF0240_00553	1.429e-133	432.0	COG0407@1|root,COG0407@2|Bacteria,1UGIQ@1239|Firmicutes,25P0U@186801|Clostridia,36RQW@31979|Clostridiaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
TH3_k127_5273323_4	697281.Mahau_1209	4.199e-102	350.0	COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24DZF@186801|Clostridia,42FW9@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
TH3_k127_5273323_2	471854.Dfer_2296	6.776e-130	425.0	COG2152@1|root,COG2152@2|Bacteria,4P1IV@976|Bacteroidetes	976|Bacteroidetes	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5273323_0	1121859.KB890750_gene255	3.098e-179	602.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,47MPU@768503|Cytophagia	976|Bacteroidetes	G	glycoside hydrolase family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
TH3_k127_5273323_3	530564.Psta_1668	1.282e-117	391.0	COG1520@1|root,COG1520@2|Bacteria,2IY7A@203682|Planctomycetes	203682|Planctomycetes	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
TH3_k127_5273323_5	1396141.BATP01000003_gene4906	2.644e-90	307.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Beta_helix,PDZ_2,PEGA,Trypsin_2
TH3_k127_5283991_5	452637.Oter_2822	8.287e-29	119.0	COG1333@1|root,COG1333@2|Bacteria,46SUY@74201|Verrucomicrobia,3K75U@414999|Opitutae	414999|Opitutae	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
TH3_k127_5283991_3	497964.CfE428DRAFT_1210	1.362e-50	194.0	2E533@1|root,32ZW9@2|Bacteria,46SZX@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5283991_1	1156937.MFUM_810001	5.112e-189	602.0	COG1158@1|root,COG1158@2|Bacteria,46S5Y@74201|Verrucomicrobia,37G72@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
TH3_k127_5283991_0	240016.ABIZ01000001_gene880	1.711e-241	766.0	COG0112@1|root,COG0112@2|Bacteria,46S5I@74201|Verrucomicrobia,2ITI6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc,LacAB_rpiB,SHMT
TH3_k127_5283991_6	521045.Kole_0482	2.286e-19	102.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SH3_3
TH3_k127_5283991_4	485913.Krac_5135	2.223e-43	170.0	COG0483@1|root,COG0483@2|Bacteria,2G6JD@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
TH3_k127_5283991_2	1028800.RG540_PA04370	2.227e-86	316.0	COG5652@1|root,COG5652@2|Bacteria,1MX6C@1224|Proteobacteria,2U18Q@28211|Alphaproteobacteria,4BBZB@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
TH3_k127_5283991_7	160799.PBOR_04215	7.18e-05	50.0	COG3459@1|root,COG3459@2|Bacteria,1V17H@1239|Firmicutes,4HFJ4@91061|Bacilli,275SG@186822|Paenibacillaceae	91061|Bacilli	G	Glycosyltransferase family 36	-	-	2.4.1.321	ko:K18786	-	-	R10832	RC00397	ko00000,ko01000	-	-	-	Glyco_hydro_36,Glyco_transf_36
TH3_k127_5291109_6	398525.KB900702_gene176	2.326e-48	184.0	COG3547@1|root,COG3547@2|Bacteria,1MUKH@1224|Proteobacteria,2TRPW@28211|Alphaproteobacteria,3JXN6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
TH3_k127_5291109_3	1121123.AUAO01000003_gene2394	1.932e-136	447.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2KIF5@204458|Caulobacterales	204458|Caulobacterales	E	Membrane dipeptidase (Peptidase family M19)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
TH3_k127_5291109_0	886293.Sinac_5714	7.575e-247	796.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IYA8@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TH3_k127_5291109_2	448385.sce7786	1.325e-153	501.0	COG3104@1|root,COG3104@2|Bacteria,1P6K2@1224|Proteobacteria	1224|Proteobacteria	E	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TH3_k127_5291109_10	344747.PM8797T_25596	3.762e-08	63.0	COG3137@1|root,COG3137@2|Bacteria,2J024@203682|Planctomycetes	203682|Planctomycetes	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
TH3_k127_5291109_5	700598.Niako_1749	6.094e-61	219.0	COG3828@1|root,COG3828@2|Bacteria,4NRZF@976|Bacteroidetes,1IVGZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
TH3_k127_5291109_9	293613.A1E_02110	1.825e-11	74.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria,47EYI@766|Rickettsiales	766|Rickettsiales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TH3_k127_5291109_1	497964.CfE428DRAFT_4660	4.144e-180	575.0	COG1520@1|root,COG1520@2|Bacteria,46TSY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_5291109_8	1121957.ATVL01000014_gene1459	1.005e-11	70.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5291109_11	740709.A10D4_00975	1.996e-05	51.0	COG1520@1|root,COG3209@1|root,COG3210@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	yeeJ	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Calx-beta,Flg_new,HYR,Laminin_G_3,PQQ_2
TH3_k127_5291109_4	269798.CHU_2897	2.773e-77	283.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes,47RAA@768503|Cytophagia	976|Bacteroidetes	M	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	PKD,UnbV_ASPIC,VCBS
TH3_k127_5291109_7	886293.Sinac_6222	1.072e-12	79.0	COG2165@1|root,COG2165@2|Bacteria,2J4VP@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_5308580_1	269482.Bcep1808_6245	4.986e-118	387.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2VI1H@28216|Betaproteobacteria,1K3UX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
TH3_k127_5308580_0	794903.OPIT5_04415	3.892e-210	659.0	COG3550@1|root,COG3550@2|Bacteria,46XT4@74201|Verrucomicrobia,3K8Y8@414999|Opitutae	414999|Opitutae	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
TH3_k127_5320088_4	857087.Metme_0775	2.419e-05	46.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,1RSAV@1236|Gammaproteobacteria,1XG2P@135618|Methylococcales	135618|Methylococcales	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
TH3_k127_5320088_3	1463917.JODC01000001_gene453	7.785e-09	61.0	COG3533@1|root,COG3533@2|Bacteria,2GM60@201174|Actinobacteria	201174|Actinobacteria	G	protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	CBM_6,Glyco_hydro_127,Laminin_G_3
TH3_k127_5320088_0	1211813.CAPH01000001_gene1171	1.72e-114	398.0	COG3345@1|root,COG3345@2|Bacteria,4P1P5@976|Bacteroidetes	976|Bacteroidetes	G	Melibiase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36N,Melibiase
TH3_k127_5320088_1	1033743.CAES01000078_gene3768	4.264e-110	367.0	COG0111@1|root,COG0111@2|Bacteria,1U2XG@1239|Firmicutes,4HF1I@91061|Bacilli,26VA2@186822|Paenibacillaceae	91061|Bacilli	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TH3_k127_5320088_2	794903.OPIT5_16430	6.837e-73	255.0	COG1082@1|root,COG1082@2|Bacteria,46WJE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_5346972_8	1081640.AGFU01000030_gene2392	2.407e-75	262.0	COG3250@1|root,COG3250@2|Bacteria,1PMI2@1224|Proteobacteria,2V04M@28211|Alphaproteobacteria,2K8HX@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_N
TH3_k127_5346972_7	370438.PTH_0469	1.247e-83	291.0	COG1163@1|root,COG1163@2|Bacteria,1TSAP@1239|Firmicutes,24EEW@186801|Clostridia,260UT@186807|Peptococcaceae	186801|Clostridia	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
TH3_k127_5346972_2	368408.Tpen_1559	1.599e-143	473.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5346972_6	926569.ANT_25800	1.16e-94	323.0	28KCX@1|root,2Z9ZQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5346972_10	682795.AciX8_0146	4.43e-06	59.0	COG2730@1|root,COG2730@2|Bacteria,3Y39Q@57723|Acidobacteria,2JI8V@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
TH3_k127_5346972_1	1123508.JH636439_gene825	2.105e-149	486.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_5346972_5	497964.CfE428DRAFT_4937	1.113e-115	382.0	COG0280@1|root,COG0280@2|Bacteria,46SP5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM phosphate acetyl butaryl transferase	-	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
TH3_k127_5346972_3	497964.CfE428DRAFT_4938	6.653e-127	416.0	COG0857@1|root,COG0857@2|Bacteria,46UEZ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	DRTGG domain	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
TH3_k127_5346972_4	240016.ABIZ01000001_gene3279	1.123e-124	410.0	COG0079@1|root,COG0079@2|Bacteria,46SFP@74201|Verrucomicrobia,2ITIN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TH3_k127_5346972_0	1210884.HG799463_gene10258	1.313e-160	516.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,2J25N@203682|Planctomycetes	203682|Planctomycetes	E	Amino acid kinase family	-	-	-	-	-	-	-	-	-	-	-	-	AA_kinase,Acetyltransf_1
TH3_k127_5346972_9	1227739.Hsw_1619	6.943e-07	58.0	COG2911@1|root,COG3291@1|root,COG3386@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,4NKIP@976|Bacteroidetes,47YDC@768503|Cytophagia	976|Bacteroidetes	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Gal_Lectin
TH3_k127_5351425_4	509191.AEDB02000002_gene1137	1.987e-24	119.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TH3_k127_5351425_5	663610.JQKO01000019_gene3046	8.208e-24	117.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,1R9FR@1224|Proteobacteria,2U76X@28211|Alphaproteobacteria,3NC43@45404|Beijerinckiaceae	28211|Alphaproteobacteria	M	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Methyltransf_21
TH3_k127_5351425_1	509191.AEDB02000002_gene1137	2.263e-95	347.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TH3_k127_5351425_6	663610.JQKO01000019_gene3046	3.516e-21	110.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,1R9FR@1224|Proteobacteria,2U76X@28211|Alphaproteobacteria,3NC43@45404|Beijerinckiaceae	28211|Alphaproteobacteria	M	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Methyltransf_21
TH3_k127_5351425_0	1122931.AUAE01000028_gene155	9.857e-259	828.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5351425_2	880526.KE386488_gene1576	9.646e-93	340.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5351425_3	1122931.AUAE01000028_gene155	2.09e-83	304.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5360677_2	1307759.JOMJ01000004_gene2828	5.737e-48	177.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,42QRD@68525|delta/epsilon subdivisions,2WMYW@28221|Deltaproteobacteria,2MC9C@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
TH3_k127_5360677_3	552811.Dehly_0387	4.362e-38	147.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi,34CR4@301297|Dehalococcoidia	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_5360677_8	796620.VIBC2010_02216	1.192e-09	67.0	2A82S@1|root,30X38@2|Bacteria,1PBW8@1224|Proteobacteria,1TIUC@1236|Gammaproteobacteria,1XZP3@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5360677_0	452637.Oter_2054	7.83e-261	812.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,3K7T7@414999|Opitutae	414999|Opitutae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
TH3_k127_5360677_5	481448.Minf_2177	1.195e-31	126.0	COG0234@1|root,COG0234@2|Bacteria,46SZ8@74201|Verrucomicrobia,37GWD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
TH3_k127_5360677_7	1123070.KB899266_gene2496	2.525e-11	68.0	COG1758@1|root,COG1758@2|Bacteria,46W29@74201|Verrucomicrobia,2IUQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	RNA polymerase activity	-	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
TH3_k127_5360677_4	1123368.AUIS01000009_gene2446	4.84e-33	133.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,1S205@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	redox protein regulator of disulfide bond formation	osmC	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
TH3_k127_5360677_1	1469607.KK073768_gene1804	6.527e-57	209.0	COG0583@1|root,COG0583@2|Bacteria,1G4W9@1117|Cyanobacteria,1HS3A@1161|Nostocales	1117|Cyanobacteria	K	PFAM Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TH3_k127_5378850_1	237368.SCABRO_03256	2.924e-07	53.0	COG0161@1|root,COG0161@2|Bacteria,2IXT2@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TH3_k127_5378850_0	477974.Daud_1570	2.276e-111	386.0	COG4147@1|root,COG4147@2|Bacteria,1V2SK@1239|Firmicutes,25DGS@186801|Clostridia,264G7@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
TH3_k127_5421589_3	903818.KI912269_gene546	1.073e-158	507.0	COG0722@1|root,COG0722@2|Bacteria,3Y2HE@57723|Acidobacteria	57723|Acidobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
TH3_k127_5421589_6	290318.Cvib_1481	1.743e-44	164.0	COG0139@1|root,COG0139@2|Bacteria,1FE2H@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
TH3_k127_5421589_10	313612.L8106_17667	6.694e-23	104.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7FN@1150|Oscillatoriales	1117|Cyanobacteria	KLT	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,WD40
TH3_k127_5421589_12	41431.PCC8801_0934	3.455e-08	59.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,3KJA0@43988|Cyanothece	1117|Cyanobacteria	S	PFAM WD-40 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,Peptidase_C14,TIR_2,WD40
TH3_k127_5421589_13	448385.sce1953	1.137e-05	58.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
TH3_k127_5421589_5	382464.ABSI01000011_gene3178	8.325e-56	217.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5421589_4	382464.ABSI01000011_gene3178	3.732e-87	314.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5421589_7	382464.ABSI01000011_gene3178	7.274e-37	141.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5421589_9	382464.ABSI01000011_gene3177	4.666e-31	128.0	2AWPW@1|root,31NKT@2|Bacteria,46WZA@74201|Verrucomicrobia,2IVVN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5421589_11	382464.ABSI01000011_gene3177	1.061e-09	64.0	2AWPW@1|root,31NKT@2|Bacteria,46WZA@74201|Verrucomicrobia,2IVVN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5421589_8	382464.ABSI01000010_gene3256	2.896e-32	134.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10,MORN,MORN_2
TH3_k127_5421589_2	234267.Acid_2676	2.45e-165	529.0	COG0620@1|root,COG0620@2|Bacteria,3Y8ZA@57723|Acidobacteria	57723|Acidobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
TH3_k127_5421589_0	1340493.JNIF01000004_gene602	8.033e-188	604.0	COG0823@1|root,COG0823@2|Bacteria,3Y6DB@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TH3_k127_5421589_1	1267533.KB906738_gene2186	1.381e-167	534.0	COG1529@1|root,COG1529@2|Bacteria,3Y3J7@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
TH3_k127_5433038_0	1123242.JH636434_gene5136	4.894e-224	706.0	COG1960@1|root,COG1960@2|Bacteria,2IXMD@203682|Planctomycetes	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TH3_k127_5433038_7	1123242.JH636435_gene830	3.238e-13	79.0	COG2165@1|root,COG2165@2|Bacteria,2J4W1@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_5433038_1	1121468.AUBR01000024_gene3021	1.011e-167	544.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,42FN9@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
TH3_k127_5433038_3	1226325.HMPREF1548_02230	3.894e-137	462.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
TH3_k127_5433038_5	497964.CfE428DRAFT_4864	1.035e-62	224.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5433038_2	886293.Sinac_6489	8.289e-141	486.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
TH3_k127_5433038_4	1192034.CAP_0893	2.305e-67	248.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
TH3_k127_5433038_6	313612.L8106_01142	9.773e-29	132.0	COG2373@1|root,COG2931@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,1G02E@1117|Cyanobacteria,1H9TQ@1150|Oscillatoriales	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,SBBP
TH3_k127_5461765_25	497964.CfE428DRAFT_4603	2.396e-66	240.0	COG0349@1|root,COG0349@2|Bacteria,46SUU@74201|Verrucomicrobia	74201|Verrucomicrobia	L	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
TH3_k127_5461765_0	530564.Psta_1928	4.409e-260	834.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,2IWYB@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TH3_k127_5461765_1	497964.CfE428DRAFT_0815	9.767e-246	766.0	COG1482@1|root,COG1482@2|Bacteria,46VQS@74201|Verrucomicrobia	74201|Verrucomicrobia	G	cell wall glycoprotein biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5461765_35	1122939.ATUD01000005_gene2726	1.862e-14	87.0	COG4402@1|root,COG4402@2|Bacteria,2I90K@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
TH3_k127_5461765_37	66875.JODY01000030_gene3928	4.622e-06	58.0	COG0789@1|root,COG1413@1|root,COG0789@2|Bacteria,COG1413@2|Bacteria,2GMKH@201174|Actinobacteria	201174|Actinobacteria	CK	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,MerR,MerR_1
TH3_k127_5461765_32	240016.ABIZ01000001_gene2350	1.437e-31	126.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia,2IUHZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
TH3_k127_5461765_31	1396418.BATQ01000106_gene5306	6.85e-43	173.0	2DTXG@1|root,33N3G@2|Bacteria,46WXU@74201|Verrucomicrobia,2IVTG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
TH3_k127_5461765_14	1121405.dsmv_1085	1.598e-124	422.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,42N95@68525|delta/epsilon subdivisions,2WJ0N@28221|Deltaproteobacteria,2MJFD@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
TH3_k127_5461765_21	1123073.KB899242_gene1477	2.589e-82	284.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1X35D@135614|Xanthomonadales	135614|Xanthomonadales	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
TH3_k127_5461765_15	1396418.BATQ01000106_gene5309	6.421e-120	394.0	COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,2IU5T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
TH3_k127_5461765_38	314256.OG2516_10581	4.585e-05	53.0	COG3637@1|root,COG3637@2|Bacteria,1RBBG@1224|Proteobacteria,2U5ED@28211|Alphaproteobacteria,2PE89@252301|Oceanicola	28211|Alphaproteobacteria	M	Outer membrane protein beta-barrel domain	lpxQ	-	-	ko:K12980	-	-	-	-	ko00000,ko01005	-	-	-	OMP_b-brl
TH3_k127_5461765_13	1396141.BATP01000009_gene2657	4.316e-128	414.0	COG2022@1|root,COG2022@2|Bacteria,46SHY@74201|Verrucomicrobia,2ITYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Thiazole biosynthesis protein ThiG	-	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
TH3_k127_5461765_22	1396418.BATQ01000015_gene4297	2.59e-81	282.0	COG2870@1|root,COG2870@2|Bacteria,46T1J@74201|Verrucomicrobia,2IVXQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	pfkB family carbohydrate kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
TH3_k127_5461765_24	497964.CfE428DRAFT_0875	9.736e-78	267.0	COG0413@1|root,COG0413@2|Bacteria,46SPN@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
TH3_k127_5461765_29	497964.CfE428DRAFT_2363	9.313e-49	177.0	2DN6W@1|root,32UIF@2|Bacteria,46WNT@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5461765_30	1128421.JAGA01000004_gene2494	5.892e-47	173.0	COG0315@1|root,COG0315@2|Bacteria,2NPNE@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
TH3_k127_5461765_26	240016.ABIZ01000001_gene2198	1.359e-62	218.0	COG0521@1|root,COG0521@2|Bacteria,46SVJ@74201|Verrucomicrobia,2IUE2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
TH3_k127_5461765_27	1396141.BATP01000057_gene2939	2.213e-53	203.0	COG0156@1|root,COG0156@2|Bacteria	2|Bacteria	E	8-amino-7-oxononanoate synthase activity	cqsA	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652,ko:K10915	ko00260,ko00780,ko01100,ko02024,ko05111,map00260,map00780,map01100,map02024,map05111	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AMP-binding,AMP-binding_C,Aminotran_1_2,PP-binding
TH3_k127_5461765_20	1125863.JAFN01000001_gene1123	2.234e-85	295.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
TH3_k127_5461765_23	1191523.MROS_2048	6.93e-81	297.0	COG0737@1|root,COG3303@1|root,COG0737@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1,SBP_bac_8,SLH
TH3_k127_5461765_36	1396418.BATQ01000185_gene2133	4.333e-07	63.0	COG3203@1|root,COG3420@1|root,COG4782@1|root,COG5184@1|root,COG3203@2|Bacteria,COG3420@2|Bacteria,COG4782@2|Bacteria,COG5184@2|Bacteria,46TZK@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_5,Pectinesterase
TH3_k127_5461765_5	452637.Oter_2235	8.595e-181	576.0	COG0460@1|root,COG0460@2|Bacteria,46TFC@74201|Verrucomicrobia,3K7MC@414999|Opitutae	414999|Opitutae	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
TH3_k127_5461765_7	903818.KI912268_gene822	3.157e-154	504.0	COG0498@1|root,COG0498@2|Bacteria	2|Bacteria	E	threonine synthase activity	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025	PALP,Thr_synth_N
TH3_k127_5461765_6	497964.CfE428DRAFT_1708	1.279e-168	539.0	COG0527@1|root,COG0527@2|Bacteria,46SIS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Amino acid kinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
TH3_k127_5461765_33	1047013.AQSP01000097_gene1961	5.754e-31	132.0	COG4122@1|root,COG4122@2|Bacteria,2NPV6@2323|unclassified Bacteria	2|Bacteria	S	Methyltransferase domain	mdmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
TH3_k127_5461765_18	1501230.ET33_33510	3.727e-90	309.0	COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes,4HACU@91061|Bacilli,26SWK@186822|Paenibacillaceae	91061|Bacilli	G	1,3--beta-D-glucan 3-glucanohydrolase	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	CBM_4_9,Glyco_hydro_16,RicinB_lectin_2
TH3_k127_5461765_10	1396141.BATP01000038_gene1207	1.658e-144	466.0	COG1172@1|root,COG1172@2|Bacteria,46V1Z@74201|Verrucomicrobia,2IVHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
TH3_k127_5461765_8	384765.SIAM614_30241	2.371e-149	490.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC transporter	alsA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
TH3_k127_5461765_12	1396141.BATP01000038_gene1209	5.264e-138	445.0	COG1879@1|root,COG1879@2|Bacteria,46XDV@74201|Verrucomicrobia,2IVKX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
TH3_k127_5461765_11	234267.Acid_1458	1.258e-140	458.0	COG2017@1|root,COG2017@2|Bacteria,3Y3D2@57723|Acidobacteria	57723|Acidobacteria	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
TH3_k127_5461765_17	1235797.C816_02559	2.01e-92	310.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,2N6GG@216572|Oscillospiraceae	186801|Clostridia	G	Class II Aldolase and Adducin N-terminal domain	araD	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
TH3_k127_5461765_2	518766.Rmar_0469	3.097e-233	733.0	COG1069@1|root,COG1069@2|Bacteria,4NEFQ@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
TH3_k127_5461765_9	926550.CLDAP_13620	5.442e-145	471.0	COG1063@1|root,COG1063@2|Bacteria,2G7MF@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase GroES domain protein	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
TH3_k127_5461765_4	1047013.AQSP01000144_gene927	9.362e-203	657.0	COG3533@1|root,COG3533@2|Bacteria,2NNW0@2323|unclassified Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	F5_F8_type_C,Glyco_hydro_127
TH3_k127_5461765_3	926569.ANT_13690	4.898e-207	654.0	COG2407@1|root,COG2407@2|Bacteria,2G84V@200795|Chloroflexi	200795|Chloroflexi	G	L-fucose isomerase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
TH3_k127_5461765_16	237368.SCABRO_00906	3.537e-110	377.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TH3_k127_5461765_19	247490.KSU1_D0861	1.623e-87	307.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TH3_k127_5461765_34	533247.CRD_00325	4.095e-17	97.0	COG2303@1|root,COG2931@1|root,COG2303@2|Bacteria,COG2931@2|Bacteria,1G31H@1117|Cyanobacteria,1HKAQ@1161|Nostocales	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GIDA,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
TH3_k127_5461765_28	1121373.KB903625_gene3160	1.526e-51	211.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4PMED@976|Bacteroidetes,47Y31@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
TH3_k127_5462300_1	880072.Desac_2552	1.121e-38	153.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2MQKP@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
TH3_k127_5462300_0	945713.IALB_0983	3.717e-99	337.0	COG4299@1|root,COG4299@2|Bacteria	2|Bacteria	G	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
TH3_k127_5462300_3	794903.OPIT5_15450	3.985e-19	96.0	COG2165@1|root,COG2165@2|Bacteria,46XJA@74201|Verrucomicrobia,3K9FD@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
TH3_k127_5462300_2	237368.SCABRO_00978	2.118e-31	134.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	BACON,DUF11,Fil_haemagg_2,Flg_new,PATR
TH3_k127_5471160_5	243090.RB5064	7.22e-29	117.0	COG0551@1|root,COG0551@2|Bacteria,2IY3X@203682|Planctomycetes	203682|Planctomycetes	CL	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
TH3_k127_5471160_1	521674.Plim_0128	2.244e-172	554.0	COG2960@1|root,COG2960@2|Bacteria,2IX6K@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
TH3_k127_5471160_2	1288963.ADIS_4732	2.925e-120	392.0	COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes,47M10@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the hyi family	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
TH3_k127_5471160_0	1235803.C825_03594	1.118e-282	912.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TH3_k127_5471160_6	1123508.JH636439_gene975	1.692e-13	85.0	COG2010@1|root,COG2010@2|Bacteria,2IXQE@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
TH3_k127_5471160_3	1077285.AGDG01000021_gene776	1.083e-83	288.0	COG1520@1|root,COG1520@2|Bacteria,4NM00@976|Bacteroidetes,2FR1A@200643|Bacteroidia,4ANP9@815|Bacteroidaceae	976|Bacteroidetes	S	unsaturated rhamnogalacturonyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans,Glyco_hydro_88,PQQ_2
TH3_k127_5471160_4	509191.AEDB02000002_gene1137	9.424e-83	294.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TH3_k127_5494239_7	439235.Dalk_2163	3.051e-16	88.0	COG2755@1|root,COG2755@2|Bacteria,1PBR7@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5494239_5	319795.Dgeo_0730	1.732e-24	105.0	COG0552@1|root,COG0552@2|Bacteria,1WI54@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
TH3_k127_5494239_2	1396141.BATP01000005_gene5990	3.898e-53	192.0	COG4185@1|root,COG4185@2|Bacteria,46XSJ@74201|Verrucomicrobia,2IWH1@203494|Verrucomicrobiae	2|Bacteria	S	zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
TH3_k127_5494239_0	313628.LNTAR_04061	4.525e-86	294.0	COG0552@1|root,COG0552@2|Bacteria	2|Bacteria	U	SRP-dependent cotranslational protein targeting to membrane	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
TH3_k127_5494239_1	1379698.RBG1_1C00001G1246	6.618e-65	235.0	COG0613@1|root,COG0613@2|Bacteria,2NPEX@2323|unclassified Bacteria	2|Bacteria	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
TH3_k127_5494239_4	497964.CfE428DRAFT_4665	2.8e-34	140.0	COG0781@1|root,COG0781@2|Bacteria,46T7V@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
TH3_k127_5494239_3	1396141.BATP01000027_gene1089	1.086e-42	181.0	COG5373@1|root,COG5373@2|Bacteria,46S9T@74201|Verrucomicrobia,2IUWT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
TH3_k127_5494239_6	1121346.KB899826_gene382	1.6e-22	99.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,26ZAP@186822|Paenibacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
TH3_k127_5526606_0	1121468.AUBR01000021_gene2825	3.737e-291	913.0	COG1449@1|root,COG1449@2|Bacteria,1UVAN@1239|Firmicutes,24B0Y@186801|Clostridia,42HS1@68295|Thermoanaerobacterales	186801|Clostridia	G	Domain of unknown function (DUF3536)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
TH3_k127_5526606_7	1227349.C170_16540	1.128e-07	61.0	2AKTD@1|root,31BKE@2|Bacteria,1VPBC@1239|Firmicutes,4HSWR@91061|Bacilli,272ZY@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5526606_2	632335.Calkr_0946	1.83e-104	355.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
TH3_k127_5526606_4	497964.CfE428DRAFT_3880	1.792e-81	284.0	COG1893@1|root,COG1893@2|Bacteria,46SK2@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	apbA	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
TH3_k127_5526606_6	330214.NIDE4047	2.482e-27	114.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
TH3_k127_5526606_3	452637.Oter_2651	7.425e-104	348.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia,3K7QD@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TH3_k127_5526606_1	278957.ABEA03000112_gene1387	6.106e-154	491.0	COG0388@1|root,COG0388@2|Bacteria,46S7B@74201|Verrucomicrobia,3K7B2@414999|Opitutae	414999|Opitutae	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
TH3_k127_5526606_5	330214.NIDE4374	3.592e-63	223.0	COG1091@1|root,COG1091@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose reductase activity	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
TH3_k127_5531978_0	742725.HMPREF9450_00266	3.63e-227	726.0	COG3408@1|root,COG3408@2|Bacteria,4NJY8@976|Bacteroidetes,2G2N9@200643|Bacteroidia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
TH3_k127_5531978_1	471854.Dfer_2640	1.343e-52	194.0	COG1082@1|root,COG1082@2|Bacteria,4NJF5@976|Bacteroidetes,47MRZ@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
TH3_k127_5563426_32	1496688.ER33_07850	1.878e-17	96.0	COG2931@1|root,COG3209@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1G39H@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Calx-beta,HemolysinCabind,RHS_repeat
TH3_k127_5563426_26	720554.Clocl_0784	4.36e-48	182.0	COG0145@1|root,COG0145@2|Bacteria,1V3GN@1239|Firmicutes,25DNJ@186801|Clostridia,3WPEF@541000|Ruminococcaceae	186801|Clostridia	EQ	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
TH3_k127_5563426_9	497964.CfE428DRAFT_1943	7.983e-127	413.0	COG2133@1|root,COG2133@2|Bacteria,46THQ@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_5563426_10	240016.ABIZ01000001_gene4842	7.599e-112	373.0	COG2115@1|root,COG2115@2|Bacteria	2|Bacteria	G	xylose isomerase activity	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
TH3_k127_5563426_2	697281.Mahau_1189	3.005e-219	712.0	COG3408@1|root,COG3408@2|Bacteria,1TPY5@1239|Firmicutes,249U8@186801|Clostridia,42EMX@68295|Thermoanaerobacterales	186801|Clostridia	G	alpha-L-rhamnosidase domain protein	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
TH3_k127_5563426_21	497964.CfE428DRAFT_6227	1.577e-67	240.0	COG0676@1|root,COG0676@2|Bacteria,46VKE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Aldose 1-epimerase	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
TH3_k127_5563426_24	452637.Oter_4232	2.237e-53	192.0	2F7MR@1|root,34028@2|Bacteria,46VN7@74201|Verrucomicrobia,3K85B@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5563426_1	452637.Oter_2033	1.242e-256	798.0	COG2268@1|root,COG2268@2|Bacteria,46TRR@74201|Verrucomicrobia,3K887@414999|Opitutae	414999|Opitutae	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
TH3_k127_5563426_37	485913.Krac_2627	1.487e-08	59.0	28XV3@1|root,2ZJRF@2|Bacteria	2|Bacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
TH3_k127_5563426_30	452637.Oter_2032	3.362e-19	88.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
TH3_k127_5563426_17	452637.Oter_2031	5.797e-82	282.0	COG0288@1|root,COG0288@2|Bacteria	2|Bacteria	P	reversible hydration of carbon dioxide	cah	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
TH3_k127_5563426_27	886293.Sinac_5104	1.685e-42	164.0	COG3468@1|root,COG3468@2|Bacteria,2J1BR@203682|Planctomycetes	203682|Planctomycetes	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5563426_36	588596.U9TEJ9	2.171e-13	76.0	COG0790@1|root,KOG1550@2759|Eukaryota	588596.U9TEJ9|-	T	ERAD pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5563426_7	497964.CfE428DRAFT_3745	4.456e-169	541.0	COG0761@1|root,COG0761@2|Bacteria,46SAR@74201|Verrucomicrobia	74201|Verrucomicrobia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	lytB	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
TH3_k127_5563426_16	497964.CfE428DRAFT_2138	6.589e-90	309.0	COG1989@1|root,COG1989@2|Bacteria,46TWT@74201|Verrucomicrobia	74201|Verrucomicrobia	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
TH3_k127_5563426_23	1121430.JMLG01000021_gene1382	2.866e-56	208.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,2619R@186807|Peptococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
TH3_k127_5563426_3	478741.JAFS01000001_gene1775	6.773e-219	688.0	COG0174@1|root,COG0174@2|Bacteria,46UCU@74201|Verrucomicrobia,37FVD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
TH3_k127_5563426_6	1396418.BATQ01000106_gene5285	5.126e-170	548.0	COG0004@1|root,COG0004@2|Bacteria,46SCE@74201|Verrucomicrobia,2ITWC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ammonium Transporter Family	-	-	-	-	-	-	-	-	-	-	-	-	Ammonium_transp
TH3_k127_5563426_25	497964.CfE428DRAFT_6239	2.161e-49	178.0	COG0347@1|root,COG0347@2|Bacteria,46VXS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	P-II
TH3_k127_5563426_4	497964.CfE428DRAFT_0232	2.824e-216	688.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5563426_39	1121887.AUDK01000010_gene1434	1.403e-05	53.0	2DP52@1|root,330JK@2|Bacteria,4NUTX@976|Bacteroidetes,1I5F0@117743|Flavobacteriia,2NWA6@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5563426_15	309807.SRU_2450	8.605e-91	319.0	COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes,1FIWB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
TH3_k127_5563426_29	886293.Sinac_3363	1.448e-26	122.0	COG4299@1|root,COG4299@2|Bacteria,2IYKU@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TH3_k127_5563426_28	1294143.H681_11855	3.414e-30	134.0	COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,1RZB6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	COG1538 Outer membrane protein	czcC	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
TH3_k127_5563426_0	404589.Anae109_4094	0.0	1178.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTXB@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
TH3_k127_5563426_19	768671.ThimaDRAFT_4573	4.16e-74	269.0	COG0845@1|root,COG0845@2|Bacteria,1PQHB@1224|Proteobacteria,1T9ZT@1236|Gammaproteobacteria,1WYMB@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
TH3_k127_5563426_34	1172180.KB911792_gene3761	1.269e-15	83.0	COG0680@1|root,COG0680@2|Bacteria,2IJ3P@201174|Actinobacteria	201174|Actinobacteria	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
TH3_k127_5563426_5	518766.Rmar_2590	1.28e-173	555.0	COG3259@1|root,COG3259@2|Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
TH3_k127_5563426_12	518766.Rmar_2589	1.2e-100	340.0	COG1941@1|root,COG1941@2|Bacteria	2|Bacteria	C	coenzyme F420 hydrogenase activity	hoxY	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
TH3_k127_5563426_14	136993.KB900626_gene2135	2.299e-94	317.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,2V487@28211|Alphaproteobacteria,36ZQF@31993|Methylocystaceae	28211|Alphaproteobacteria	CH	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
TH3_k127_5563426_8	518766.Rmar_2586	6.37e-129	422.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	asrA	-	-	ko:K16950	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4_22
TH3_k127_5563426_13	452637.Oter_1130	6.233e-99	334.0	COG0484@1|root,COG0484@2|Bacteria,46S6P@74201|Verrucomicrobia,3K8ZD@414999|Opitutae	414999|Opitutae	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
TH3_k127_5563426_22	237368.SCABRO_03960	4.605e-67	236.0	COG0705@1|root,COG0705@2|Bacteria,2IZZY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TH3_k127_5563426_20	1123371.ATXH01000009_gene1101	6.226e-69	242.0	COG1912@1|root,COG1912@2|Bacteria,2GHAQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
TH3_k127_5563426_11	886293.Sinac_0152	6.9e-101	334.0	COG4221@1|root,COG4221@2|Bacteria,2IXHG@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TH3_k127_5563426_35	452637.Oter_3848	2.995e-14	76.0	2EPKD@1|root,33H70@2|Bacteria,46WC0@74201|Verrucomicrobia,3K89T@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5563426_38	1192034.CAP_1634	2.081e-08	63.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Sigma54_activat,Yop-YscD_cpl
TH3_k127_55890_3	1122609.AUGT01000006_gene1453	5.586e-19	92.0	2CZQD@1|root,32T6U@2|Bacteria,2HDRX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_55890_1	105425.BBPL01000045_gene3199	1.377e-72	254.0	COG0500@1|root,COG2226@2|Bacteria,2I3BB@201174|Actinobacteria,2NNHE@228398|Streptacidiphilus	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TH3_k127_55890_0	319003.Bra1253DRAFT_01013	1.678e-150	488.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2TRET@28211|Alphaproteobacteria,3JQXY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate	-	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
TH3_k127_55890_2	640511.BC1002_6686	9.516e-69	241.0	298PG@1|root,2ZVTY@2|Bacteria,1RIKV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_562913_2	497964.CfE428DRAFT_5501	1.407e-124	402.0	COG0008@1|root,COG0008@2|Bacteria,46S4X@74201|Verrucomicrobia	74201|Verrucomicrobia	J	glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
TH3_k127_562913_0	886293.Sinac_2090	2.569e-201	635.0	COG0823@1|root,COG0823@2|Bacteria,2IZ00@203682|Planctomycetes	203682|Planctomycetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	-
TH3_k127_562913_4	1121468.AUBR01000005_gene35	1.65e-10	74.0	COG1716@1|root,COG1716@2|Bacteria,1V5U0@1239|Firmicutes,24IDE@186801|Clostridia,42H0N@68295|Thermoanaerobacterales	186801|Clostridia	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,Yop-YscD_cpl
TH3_k127_562913_1	382464.ABSI01000006_gene864	2.874e-162	518.0	COG1225@1|root,COG1225@2|Bacteria,46TJA@74201|Verrucomicrobia,2ITIP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TH3_k127_562913_6	866771.HMPREF9296_1795	4.144e-07	64.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
TH3_k127_562913_5	56780.SYN_03067	2.078e-09	65.0	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SmpA_OmlA,SusD-like_3
TH3_k127_5634950_0	671143.DAMO_1057	4.593e-145	497.0	COG1391@1|root,COG1391@2|Bacteria	2|Bacteria	H	[glutamate-ammonia-ligase] adenylyltransferase activity	glnE	GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
TH3_k127_5634950_1	398767.Glov_2755	2.779e-63	229.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	exoA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K16557	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
TH3_k127_568194_2	1235803.C825_03120	9.838e-64	231.0	COG1331@1|root,COG1331@2|Bacteria,4NIS8@976|Bacteroidetes,2FRC4@200643|Bacteroidia	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_568194_1	1492737.FEM08_16420	5.517e-224	726.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,DUF5054,Glyco_hydro_38,Glyco_hydro_38C
TH3_k127_568194_0	452637.Oter_1883	4.893e-311	972.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TH3_k127_568194_3	1267535.KB906767_gene5108	6.372e-52	195.0	COG0577@1|root,COG0577@2|Bacteria,3Y31H@57723|Acidobacteria,2JITF@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TH3_k127_5689760_9	886293.Sinac_4596	6.356e-09	57.0	2DBS0@1|root,2ZANT@2|Bacteria,2IY4P@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5689760_6	1396141.BATP01000007_gene5566	6.532e-70	246.0	COG0767@1|root,COG0767@2|Bacteria,46SXR@74201|Verrucomicrobia,2ITY5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Permease MlaE	-	-	-	-	-	-	-	-	-	-	-	-	MlaE
TH3_k127_5689760_3	644282.Deba_0203	6.165e-84	286.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
TH3_k127_5689760_10	525146.Ddes_0534	2.336e-06	59.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,42SCT@68525|delta/epsilon subdivisions,2WPA7@28221|Deltaproteobacteria,2MC24@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
TH3_k127_5689760_4	452637.Oter_2116	4.421e-78	273.0	COG4956@1|root,COG4956@2|Bacteria,46TFJ@74201|Verrucomicrobia,3K8ZF@414999|Opitutae	414999|Opitutae	S	SMART Nucleotide binding protein PINc	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5689760_11	1300345.LF41_2927	0.0001663	49.0	2DSC2@1|root,33FFW@2|Bacteria,1QJUP@1224|Proteobacteria,1THW7@1236|Gammaproteobacteria,1X8XP@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
TH3_k127_5689760_0	497964.CfE428DRAFT_0079	1.359e-174	558.0	COG0277@1|root,COG0277@2|Bacteria,46SFA@74201|Verrucomicrobia	74201|Verrucomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
TH3_k127_5689760_7	935845.JADQ01000029_gene1230	4.35e-54	218.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
TH3_k127_5689760_8	1089547.KB913013_gene3400	5.158e-11	77.0	COG1874@1|root,COG2133@1|root,COG1874@2|Bacteria,COG2133@2|Bacteria,4NIJA@976|Bacteroidetes,47NB2@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,GSDH,I-set,Ig_3
TH3_k127_5689760_2	234267.Acid_2668	1.001e-111	371.0	COG0407@1|root,COG0407@2|Bacteria,3Y8YA@57723|Acidobacteria	57723|Acidobacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
TH3_k127_5689760_5	404380.Gbem_3420	2.958e-75	259.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2WM37@28221|Deltaproteobacteria,43TDJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
TH3_k127_5689760_1	794903.OPIT5_02510	1.077e-121	401.0	COG4974@1|root,COG4974@2|Bacteria,46UB9@74201|Verrucomicrobia,3K9DD@414999|Opitutae	414999|Opitutae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
TH3_k127_5696410_1	1123242.JH636435_gene944	1.908e-98	338.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_5696410_4	1123319.AUBE01000006_gene3230	8.635e-26	118.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
TH3_k127_5696410_3	234267.Acid_0687	1.907e-76	279.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,3Y6TZ@57723|Acidobacteria	2|Bacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
TH3_k127_5696410_0	1123242.JH636434_gene4800	4.057e-121	404.0	COG2271@1|root,COG2271@2|Bacteria,2IZBA@203682|Planctomycetes	203682|Planctomycetes	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TH3_k127_5696410_2	234267.Acid_1327	1.303e-81	291.0	COG0318@1|root,COG0318@2|Bacteria,3Y65U@57723|Acidobacteria	57723|Acidobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
TH3_k127_5703266_24	1112217.PPL19_20816	8.175e-13	78.0	COG2801@1|root,COG2801@2|Bacteria,1MWVQ@1224|Proteobacteria,1RN12@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28,HTH_32,rve
TH3_k127_5703266_1	94624.Bpet1409	2.102e-231	735.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2VK01@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Resolvase domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TH3_k127_5703266_17	1366050.N234_27952	3.089e-35	141.0	COG3415@1|root,COG3415@2|Bacteria,1RKUV@1224|Proteobacteria,2WFVI@28216|Betaproteobacteria,1KI6K@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29
TH3_k127_5703266_20	420324.KI911932_gene324	1.641e-16	83.0	2EHAG@1|root,3394C@2|Bacteria,1NK4E@1224|Proteobacteria,2UJZB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Family of unknown function (DUF5372)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5372
TH3_k127_5703266_28	1515746.HR45_16165	0.0001618	50.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,1MWVQ@1224|Proteobacteria,1RN12@1236|Gammaproteobacteria,2QEPQ@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_29,rve
TH3_k127_5703266_12	1185876.BN8_04770	6.285e-77	274.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47K7H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_5703266_26	661478.OP10G_4722	1.018e-09	73.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
TH3_k127_5703266_7	497964.CfE428DRAFT_1446	3.675e-123	436.0	COG2133@1|root,COG2133@2|Bacteria,46UME@74201|Verrucomicrobia	74201|Verrucomicrobia	G	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TH3_k127_5703266_3	794903.OPIT5_28445	1.85e-182	580.0	COG0677@1|root,COG0677@2|Bacteria	2|Bacteria	M	UDP-N-acetyl-D-mannosamine dehydrogenase activity	wbpA	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TH3_k127_5703266_5	1442599.JAAN01000005_gene1008	9.581e-150	480.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1X46C@135614|Xanthomonadales	135614|Xanthomonadales	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TH3_k127_5703266_14	886293.Sinac_6555	1.067e-67	238.0	COG1131@1|root,COG1131@2|Bacteria,2IY18@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_5703266_25	661478.OP10G_3704	3.472e-12	76.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	pilI	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
TH3_k127_5703266_15	497964.CfE428DRAFT_1467	6.096e-62	220.0	COG0131@1|root,COG0131@2|Bacteria,46SR2@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
TH3_k127_5703266_16	497964.CfE428DRAFT_0896	4.642e-43	164.0	COG1595@1|root,COG1595@2|Bacteria,46V3R@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_5703266_2	497964.CfE428DRAFT_3932	9.255e-201	644.0	COG1530@1|root,COG1530@2|Bacteria,46S5S@74201|Verrucomicrobia	74201|Verrucomicrobia	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
TH3_k127_5703266_11	452637.Oter_0292	4.094e-85	296.0	COG0772@1|root,COG0772@2|Bacteria,46SQT@74201|Verrucomicrobia,3K7H4@414999|Opitutae	414999|Opitutae	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
TH3_k127_5703266_10	481448.Minf_1718	4.146e-91	326.0	COG0768@1|root,COG0768@2|Bacteria,46SE6@74201|Verrucomicrobia,37G03@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Peptidase_M56,Transpeptidase
TH3_k127_5703266_18	457570.Nther_0516	1.925e-29	128.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
TH3_k127_5703266_4	1123070.KB899252_gene961	1.21e-155	497.0	COG1077@1|root,COG1077@2|Bacteria,46SAA@74201|Verrucomicrobia,2ITYI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
TH3_k127_5703266_0	497964.CfE428DRAFT_1447	0.0	1159.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,46T85@74201|Verrucomicrobia	74201|Verrucomicrobia	OU	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
TH3_k127_5703266_23	180281.CPCC7001_1993	2.53e-13	72.0	COG0732@1|root,COG0732@2|Bacteria,1G6EU@1117|Cyanobacteria,22TSW@167375|Cyanobium	1117|Cyanobacteria	L	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
TH3_k127_5703266_27	1078085.HMPREF1210_01122	3.4e-05	54.0	2DDVZ@1|root,2ZJI2@2|Bacteria,1W5EF@1239|Firmicutes,4I14U@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5703266_21	1042209.HK44_027725	2.055e-15	78.0	COG0732@1|root,COG0732@2|Bacteria,1MXVH@1224|Proteobacteria,1S29W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0732 Restriction endonuclease S subunits	hsdS	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
TH3_k127_5703266_13	1396141.BATP01000025_gene931	8.842e-77	271.0	COG0053@1|root,COG0053@2|Bacteria,46SPJ@74201|Verrucomicrobia,2IUZU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
TH3_k127_5703266_19	649639.Bcell_1282	2.796e-28	120.0	2E58T@1|root,33017@2|Bacteria,1VARJ@1239|Firmicutes,4HKU9@91061|Bacilli,1ZHPC@1386|Bacillus	91061|Bacilli	S	Uncharacterised protein family (UPF0158)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0158
TH3_k127_5703266_9	1303518.CCALI_02909	4.88e-106	357.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ytaP	-	-	-	-	-	-	-	-	-	-	-	AXE1,Abhydrolase_7,DLH,Peptidase_S15,Peptidase_S9
TH3_k127_5703266_22	234267.Acid_0995	4.906e-14	84.0	COG3391@1|root,COG3391@2|Bacteria,3Y7I2@57723|Acidobacteria	57723|Acidobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5703266_8	929562.Emtol_1205	1.386e-111	366.0	COG1028@1|root,COG1028@2|Bacteria,4NJKA@976|Bacteroidetes,47KN3@768503|Cytophagia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TH3_k127_5703266_6	481448.Minf_1705	1.778e-132	439.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia,37G39@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Trypsin-like serine protease	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
TH3_k127_5703670_2	671143.DAMO_0981	2.127e-173	550.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,2NQV4@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
TH3_k127_5703670_29	1123508.JH636456_gene119	8.643e-12	72.0	COG3335@1|root,COG3335@2|Bacteria,2J1BU@203682|Planctomycetes	203682|Planctomycetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
TH3_k127_5703670_21	1210884.HG799479_gene15512	1.255e-29	126.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32,HTH_33
TH3_k127_5703670_20	670487.Ocepr_1062	2.39e-35	140.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,1WN2N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
TH3_k127_5703670_22	1396141.BATP01000023_gene577	1.637e-27	122.0	COG0132@1|root,COG0132@2|Bacteria,46VJB@74201|Verrucomicrobia,2IUDQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	AAA domain	-	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
TH3_k127_5703670_7	497964.CfE428DRAFT_1043	6.737e-128	418.0	COG0389@1|root,COG0389@2|Bacteria,46SNK@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
TH3_k127_5703670_10	1122176.KB903539_gene1325	7.248e-125	423.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TH3_k127_5703670_26	1210884.HG799466_gene12517	8.316e-16	87.0	COG4968@1|root,COG4968@2|Bacteria,2J4X1@203682|Planctomycetes	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_5703670_24	452637.Oter_2184	4.382e-23	116.0	COG3291@1|root,COG3291@2|Bacteria,46Z7J@74201|Verrucomicrobia,3KA3F@414999|Opitutae	2|Bacteria	S	SMART Immunoglobulin C2 type	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,Ig_3,VCBS
TH3_k127_5703670_28	160799.PBOR_01905	1.959e-14	88.0	COG1409@1|root,COG3250@1|root,COG1409@2|Bacteria,COG3250@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,26TEF@186822|Paenibacillaceae	91061|Bacilli	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Metallophos,PA14,Pur_ac_phosph_N,fn3
TH3_k127_5703670_31	998674.ATTE01000001_gene3175	0.0002307	55.0	COG1649@1|root,COG4932@1|root,COG1649@2|Bacteria,COG4932@2|Bacteria,1NP4V@1224|Proteobacteria	1224|Proteobacteria	G	Hypothetical glycosyl hydrolase 6	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42M
TH3_k127_5703670_19	671143.DAMO_0701	1.66e-36	150.0	COG0500@1|root,COG2226@2|Bacteria,2NRU8@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
TH3_k127_5703670_11	1116472.MGMO_20c00270	7.643e-113	379.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,1RMNS@1236|Gammaproteobacteria,1XDKP@135618|Methylococcales	1236|Gammaproteobacteria	C	Tryptophan halogenase	pltM	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
TH3_k127_5703670_6	485918.Cpin_1862	3.591e-129	424.0	COG0500@1|root,COG2226@2|Bacteria,4NGN8@976|Bacteroidetes,1IUWM@117747|Sphingobacteriia	976|Bacteroidetes	Q	O-methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
TH3_k127_5703670_9	153721.MYP_192	3.266e-127	420.0	COG0644@1|root,COG0644@2|Bacteria,4NEI6@976|Bacteroidetes,47MPG@768503|Cytophagia	976|Bacteroidetes	C	Tryptophan halogenase	fixC	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
TH3_k127_5703670_12	1379270.AUXF01000004_gene3002	1.471e-109	374.0	COG2986@1|root,COG2986@2|Bacteria,1ZTEG@142182|Gemmatimonadetes	2|Bacteria	E	Aromatic amino acid lyase	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009698,GO:0009699,GO:0009987,GO:0016043,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019439,GO:0019748,GO:0019752,GO:0022607,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044550,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052883,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606	4.3.1.23,4.3.1.3	ko:K01745,ko:K10774	ko00340,ko00350,ko01100,map00340,map00350,map01100	M00045	R00737,R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
TH3_k127_5703670_32	2423.NA23_0209590	0.0002641	51.0	COG1413@1|root,COG1413@2|Bacteria,2GDN4@200918|Thermotogae	200918|Thermotogae	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
TH3_k127_5703670_18	1210884.HG799462_gene8039	1.882e-44	173.0	COG0845@1|root,COG0845@2|Bacteria,2IYMS@203682|Planctomycetes	203682|Planctomycetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TH3_k127_5703670_14	661478.OP10G_3898	2.151e-70	250.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10,T2SSG
TH3_k127_5703670_5	452637.Oter_1656	7.695e-134	430.0	COG2013@1|root,COG2013@2|Bacteria,46SY6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
TH3_k127_5703670_3	1403819.BATR01000098_gene3267	2.176e-135	439.0	COG0042@1|root,COG0042@2|Bacteria,46TSS@74201|Verrucomicrobia,2ITU4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
TH3_k127_5703670_8	234267.Acid_4784	1.3e-127	424.0	COG0591@1|root,COG0591@2|Bacteria,3Y419@57723|Acidobacteria	57723|Acidobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
TH3_k127_5703670_0	671143.DAMO_0980	2.919e-278	871.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NP1J@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
TH3_k127_5703670_13	215803.DB30_6514	6.18e-75	265.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2YYHJ@29|Myxococcales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
TH3_k127_5703670_1	497964.CfE428DRAFT_1483	1.928e-212	666.0	COG0436@1|root,COG0436@2|Bacteria,46TMR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TH3_k127_5703670_15	497964.CfE428DRAFT_5394	8.581e-60	229.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
TH3_k127_5703670_30	497964.CfE428DRAFT_1483	1.495e-06	49.0	COG0436@1|root,COG0436@2|Bacteria,46TMR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TH3_k127_5703670_23	497964.CfE428DRAFT_5124	5.105e-25	109.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,LytTR,PAS,PAS_3,PAS_9,Response_reg,dCache_1
TH3_k127_5703670_4	794903.OPIT5_30480	5.259e-134	439.0	COG0501@1|root,COG0501@2|Bacteria,46TVV@74201|Verrucomicrobia,3K72R@414999|Opitutae	414999|Opitutae	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
TH3_k127_5703670_17	1042209.HK44_007325	1.478e-49	180.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
TH3_k127_5703670_16	1437824.BN940_09076	2.773e-58	208.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2VPN0@28216|Betaproteobacteria,3T3HF@506|Alcaligenaceae	28216|Betaproteobacteria	S	Iron-sulfur cluster assembly protein	sufT	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
TH3_k127_5703670_25	452637.Oter_0604	1.699e-16	81.0	COG0520@1|root,COG0520@2|Bacteria,46S58@74201|Verrucomicrobia,3K7QK@414999|Opitutae	414999|Opitutae	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
TH3_k127_580844_8	1201290.M902_0688	1.124e-07	53.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2MT4C@213481|Bdellovibrionales,2WNZS@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
TH3_k127_580844_5	290315.Clim_0624	5.313e-14	75.0	COG1826@1|root,COG1826@2|Bacteria,1FE6Y@1090|Chlorobi	1090|Chlorobi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
TH3_k127_580844_2	452637.Oter_4241	3.002e-49	188.0	COG0805@1|root,COG0805@2|Bacteria,46T26@74201|Verrucomicrobia,3K8EP@414999|Opitutae	414999|Opitutae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
TH3_k127_580844_1	402777.KB235903_gene711	9.225e-128	421.0	COG0500@1|root,COG0500@2|Bacteria,1GHCT@1117|Cyanobacteria,1HHS8@1150|Oscillatoriales	1117|Cyanobacteria	Q	Putative zinc binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
TH3_k127_580844_4	1396141.BATP01000059_gene2442	1.962e-17	88.0	COG5620@1|root,COG5620@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1851,GAD-like
TH3_k127_580844_3	1396141.BATP01000059_gene2441	5.627e-49	179.0	COG5620@1|root,COG5620@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1851,GAD-like
TH3_k127_580844_7	314230.DSM3645_12146	6.782e-10	63.0	COG1089@1|root,COG1089@2|Bacteria,2IWZ4@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
TH3_k127_580844_0	880072.Desac_1923	3.503e-146	465.0	COG2519@1|root,COG2519@2|Bacteria,1MXAK@1224|Proteobacteria,42NCI@68525|delta/epsilon subdivisions,2WJUH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
TH3_k127_580844_6	1469607.KK073768_gene4368	3.33e-10	60.0	COG1598@1|root,COG1598@2|Bacteria,1GA5T@1117|Cyanobacteria,1HTEU@1161|Nostocales	1117|Cyanobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
TH3_k127_5832891_0	314230.DSM3645_14120	3.789e-86	293.0	COG1082@1|root,COG1082@2|Bacteria,2IXNX@203682|Planctomycetes	203682|Planctomycetes	G	COG1082 Sugar phosphate	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
TH3_k127_5832891_2	1173029.JH980292_gene2834	4.942e-29	117.0	COG1598@1|root,COG1598@2|Bacteria,1G7N4@1117|Cyanobacteria,1HDCI@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
TH3_k127_5832891_3	403833.Pmob_1240	1.638e-17	84.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
TH3_k127_5832891_4	290317.Cpha266_1712	0.0002689	46.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
TH3_k127_5832891_1	443143.GM18_2872	4.183e-31	130.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,42N9K@68525|delta/epsilon subdivisions,2WINH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM N-6 DNA methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
TH3_k127_5835229_2	1278073.MYSTI_02970	1.698e-38	166.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2WT5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_C,PKD,Pur_ac_phosph_N
TH3_k127_5835229_3	153721.MYP_3351	5.489e-08	66.0	COG1404@1|root,COG1409@1|root,COG2273@1|root,COG1404@2|Bacteria,COG1409@2|Bacteria,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_4_9,CHB_HEX_C_1,CotH,DUF5006,DUF5014,LTD,Metallophos,Peptidase_M43
TH3_k127_5835229_1	497964.CfE428DRAFT_4549	2.698e-65	231.0	COG0800@1|root,COG0800@2|Bacteria,46VG5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	TIGRFAM 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
TH3_k127_5835229_0	1396418.BATQ01000185_gene2103	4.097e-142	469.0	COG1572@1|root,COG2010@1|root,COG2133@1|root,COG1572@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
TH3_k127_5837759_1	443143.GM18_0683	5.761e-195	621.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
TH3_k127_5837759_0	481448.Minf_2402	7.19e-221	703.0	COG0445@1|root,COG0445@2|Bacteria,46SID@74201|Verrucomicrobia,37GAP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
TH3_k127_5837759_3	1396418.BATQ01000146_gene3489	6.704e-102	340.0	COG1082@1|root,COG1082@2|Bacteria,46SR1@74201|Verrucomicrobia,2IW0I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_5837759_8	1303518.CCALI_01326	3.414e-41	155.0	COG0393@1|root,COG0393@2|Bacteria	2|Bacteria	S	Putative heavy-metal-binding	ybjQ	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
TH3_k127_5837759_4	744872.Spica_1339	1.199e-73	256.0	COG0217@1|root,COG0217@2|Bacteria,2J634@203691|Spirochaetes	203691|Spirochaetes	K	Transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
TH3_k127_5837759_2	314230.DSM3645_16385	2.513e-126	438.0	COG4258@1|root,COG4258@2|Bacteria,2IYH7@203682|Planctomycetes	203682|Planctomycetes	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
TH3_k127_5837759_6	269799.Gmet_1270	8.333e-66	245.0	COG3170@1|root,COG3170@2|Bacteria,1MY6X@1224|Proteobacteria,42TBE@68525|delta/epsilon subdivisions,2WPBV@28221|Deltaproteobacteria,43U5N@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5837759_7	452637.Oter_0685	4.257e-61	219.0	COG0767@1|root,COG0767@2|Bacteria,46ZIM@74201|Verrucomicrobia,3K7D7@414999|Opitutae	414999|Opitutae	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
TH3_k127_5837759_5	1158345.JNLL01000001_gene159	1.772e-73	255.0	COG1127@1|root,COG1127@2|Bacteria,2G3XY@200783|Aquificae	200783|Aquificae	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
TH3_k127_5837759_9	1123371.ATXH01000005_gene2035	1.304e-38	157.0	COG1463@1|root,COG1463@2|Bacteria,2GGR8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
TH3_k127_5881034_37	240016.ABIZ01000001_gene5219	1.727e-11	76.0	COG0457@1|root,COG1450@1|root,COG0457@2|Bacteria,COG1450@2|Bacteria,46TXY@74201|Verrucomicrobia,2ITGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Bacterial type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
TH3_k127_5881034_13	497964.CfE428DRAFT_4611	3.407e-97	342.0	COG4972@1|root,COG4972@2|Bacteria,46UI7@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
TH3_k127_5881034_8	497964.CfE428DRAFT_4613	4.108e-145	466.0	COG0451@1|root,COG0451@2|Bacteria,46S80@74201|Verrucomicrobia	74201|Verrucomicrobia	GM	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
TH3_k127_5881034_12	497964.CfE428DRAFT_4614	4.224e-117	393.0	COG2148@1|root,COG2148@2|Bacteria,46TSZ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
TH3_k127_5881034_35	240016.ABIZ01000001_gene498	6.154e-14	82.0	2DKIU@1|root,309MI@2|Bacteria,46W7D@74201|Verrucomicrobia,2IUZM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
TH3_k127_5881034_26	452637.Oter_0284	5.643e-32	138.0	2DT8D@1|root,33J57@2|Bacteria,46WBF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
TH3_k127_5881034_24	118168.MC7420_6062	8.122e-40	164.0	COG0438@1|root,COG0438@2|Bacteria,1G0EX@1117|Cyanobacteria,1H9C2@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
TH3_k127_5881034_28	313606.M23134_05981	1.368e-29	128.0	COG4123@1|root,COG4123@2|Bacteria,4NKPF@976|Bacteroidetes,47SG7@768503|Cytophagia	976|Bacteroidetes	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
TH3_k127_5881034_21	1396141.BATP01000035_gene4047	7.45e-51	192.0	COG1922@1|root,COG1922@2|Bacteria,46VQJ@74201|Verrucomicrobia,2IUM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase WecB/TagA/CpsF family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WecB
TH3_k127_5881034_5	240016.ABIZ01000001_gene2673	1.204e-174	580.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,46U7Q@74201|Verrucomicrobia,2ITXJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,NAD_synthase
TH3_k127_5881034_20	497964.CfE428DRAFT_0088	1.182e-53	199.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TH3_k127_5881034_10	1499967.BAYZ01000026_gene1631	1.088e-128	434.0	COG0367@1|root,COG0367@2|Bacteria,2NNKE@2323|unclassified Bacteria	2|Bacteria	E	PFAM asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TH3_k127_5881034_31	926551.KB900703_gene1072	4.82e-17	89.0	COG4124@1|root,COG4124@2|Bacteria,4NEZG@976|Bacteroidetes,1HYFM@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Glyco_hydro_26
TH3_k127_5881034_2	234267.Acid_2264	5.565e-226	711.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
TH3_k127_5881034_4	234267.Acid_2265	7.293e-216	678.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TH3_k127_5881034_3	234267.Acid_2266	8.769e-219	704.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
TH3_k127_5881034_19	1122135.KB893134_gene3934	8.042e-57	207.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
TH3_k127_5881034_15	1122135.KB893134_gene3933	2.487e-95	320.0	COG0518@1|root,COG0518@2|Bacteria,1Q2PQ@1224|Proteobacteria,2U196@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	glutamine amidotransferase	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
TH3_k127_5881034_36	278957.ABEA03000195_gene491	1.762e-12	70.0	28X6Y@1|root,2ZJ59@2|Bacteria,46WIZ@74201|Verrucomicrobia,3K8DC@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5881034_32	382464.ABSI01000005_gene1185	1.138e-16	85.0	COG5010@1|root,COG5010@2|Bacteria	2|Bacteria	-	-	tadD	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	BCSC_C,SPOR,TPR_16,TPR_19,TPR_8
TH3_k127_5881034_22	497964.CfE428DRAFT_4443	4.878e-44	174.0	COG0561@1|root,COG0561@2|Bacteria,46SWT@74201|Verrucomicrobia	74201|Verrucomicrobia	S	haloacid dehalogenase-like hydrolase	cof	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
TH3_k127_5881034_0	497964.CfE428DRAFT_4284	3.198e-259	812.0	COG0674@1|root,COG0674@2|Bacteria,46SM9@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
TH3_k127_5881034_7	497964.CfE428DRAFT_4282	3.629e-151	482.0	COG1013@1|root,COG1013@2|Bacteria,46SRY@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
TH3_k127_5881034_27	269799.Gmet_2576	1.239e-30	127.0	COG5319@1|root,COG5319@2|Bacteria,1RKDX@1224|Proteobacteria,42SDV@68525|delta/epsilon subdivisions,2WPXR@28221|Deltaproteobacteria,43T4D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
TH3_k127_5881034_17	756272.Plabr_2090	5.646e-78	268.0	COG4099@1|root,COG4099@2|Bacteria,2IZGT@203682|Planctomycetes	203682|Planctomycetes	P	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Peptidase_S9
TH3_k127_5881034_30	909663.KI867150_gene2927	2.094e-21	102.0	COG1042@1|root,COG1670@1|root,COG1042@2|Bacteria,COG1670@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MR1B@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CoA binding domain	acs	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
TH3_k127_5881034_11	497964.CfE428DRAFT_5019	2.612e-117	388.0	COG0077@1|root,COG0077@2|Bacteria,46U8V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
TH3_k127_5881034_23	1121324.CLIT_23c01830	1.86e-40	158.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
TH3_k127_5881034_6	1210884.HG799467_gene13206	2.95e-171	547.0	COG0205@1|root,COG0205@2|Bacteria,2IXXF@203682|Planctomycetes	203682|Planctomycetes	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
TH3_k127_5881034_9	497964.CfE428DRAFT_3906	1.324e-144	464.0	COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
TH3_k127_5881034_16	1121104.AQXH01000001_gene1195	2.031e-88	301.0	COG1012@1|root,COG1012@2|Bacteria,4NZV1@976|Bacteroidetes	976|Bacteroidetes	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
TH3_k127_5881034_25	1205680.CAKO01000002_gene2136	1.756e-34	147.0	COG3848@1|root,COG3848@2|Bacteria,1R7DS@1224|Proteobacteria,2U3SK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5881034_29	1123073.KB899242_gene1109	3.034e-25	124.0	COG1470@1|root,COG3210@1|root,COG4625@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG5492@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,Haemagg_act,He_PIG,Hint_2,TIG
TH3_k127_5881034_34	153721.MYP_567	7.018e-15	85.0	COG3291@1|root,COG4099@1|root,COG5295@1|root,COG5297@1|root,COG3291@2|Bacteria,COG4099@2|Bacteria,COG5295@2|Bacteria,COG5297@2|Bacteria,4NF6Q@976|Bacteroidetes,47KN7@768503|Cytophagia	976|Bacteroidetes	GUW	candidate b-glycosidase, glycoside hydrolase family 8 protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_3,M60-like_N,NosD,Peptidase_M60
TH3_k127_5881034_33	675814.VIC_000680	4.89e-16	89.0	COG3469@1|root,COG3979@1|root,COG3469@2|Bacteria,COG3979@2|Bacteria,1MUUS@1224|Proteobacteria,1RYTJ@1236|Gammaproteobacteria,1XUGW@135623|Vibrionales	135623|Vibrionales	G	Glycosyl hydrolases family 18	chiA	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
TH3_k127_5881034_1	497964.CfE428DRAFT_3146	1.017e-239	758.0	COG0028@1|root,COG0028@2|Bacteria,46S72@74201|Verrucomicrobia	74201|Verrucomicrobia	EH	thiamine pyrophosphate protein TPP binding domain protein	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TH3_k127_5881034_18	497964.CfE428DRAFT_3392	5.916e-72	254.0	COG3828@1|root,COG3828@2|Bacteria,46UCF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
TH3_k127_5881034_14	1303518.CCALI_00783	2.2e-96	337.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_5881676_15	794903.OPIT5_08425	5.078e-12	74.0	COG4968@1|root,COG4968@2|Bacteria,46YJJ@74201|Verrucomicrobia,3K9QQ@414999|Opitutae	414999|Opitutae	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5881676_17	1297617.JPJD01000023_gene1562	0.0001245	54.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,267R3@186813|unclassified Clostridiales	186801|Clostridia	M	tail specific protease	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
TH3_k127_5881676_11	1396141.BATP01000023_gene616	1.386e-47	180.0	2B5SN@1|root,31YNB@2|Bacteria,46XHC@74201|Verrucomicrobia,2IVXC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5881676_10	382464.ABSI01000020_gene153	1.652e-51	190.0	COG2194@1|root,COG2194@2|Bacteria,46XHR@74201|Verrucomicrobia,2IVYD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5881676_4	293826.Amet_3280	3.413e-182	581.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,36F9T@31979|Clostridiaceae	186801|Clostridia	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
TH3_k127_5881676_12	706587.Desti_0559	8.246e-35	143.0	COG1225@1|root,COG1225@2|Bacteria,1NZF4@1224|Proteobacteria,42ZRX@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5881676_3	234267.Acid_7735	7.566e-222	699.0	COG1032@1|root,COG1032@2|Bacteria,3Y4FB@57723|Acidobacteria	57723|Acidobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
TH3_k127_5881676_7	1396418.BATQ01000107_gene5393	6.506e-71	248.0	COG1633@1|root,COG1633@2|Bacteria,46VFF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5881676_6	497964.CfE428DRAFT_2012	8.805e-74	260.0	COG0761@1|root,COG0761@2|Bacteria,46SYM@74201|Verrucomicrobia	74201|Verrucomicrobia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
TH3_k127_5881676_13	1340493.JNIF01000003_gene1913	2.072e-26	111.0	COG1846@1|root,COG1846@2|Bacteria,3Y7YY@57723|Acidobacteria	57723|Acidobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
TH3_k127_5881676_16	240016.ABIZ01000001_gene4454	3.381e-10	68.0	2BJXT@1|root,32EAA@2|Bacteria,46XIQ@74201|Verrucomicrobia,2IW0S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5881676_5	485913.Krac_6798	6.43e-84	295.0	COG0604@1|root,COG0604@2|Bacteria,2G6DS@200795|Chloroflexi	200795|Chloroflexi	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
TH3_k127_5881676_2	497964.CfE428DRAFT_0484	0.0	1022.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
TH3_k127_5881676_9	452637.Oter_0229	4.895e-56	199.0	COG0049@1|root,COG0049@2|Bacteria,46UH0@74201|Verrucomicrobia,3K7QA@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
TH3_k127_5881676_8	794903.OPIT5_02450	1.155e-65	226.0	COG0048@1|root,COG0048@2|Bacteria,46SQR@74201|Verrucomicrobia,3K7YQ@414999|Opitutae	414999|Opitutae	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
TH3_k127_5881676_0	497964.CfE428DRAFT_5595	0.0	2046.0	COG0086@1|root,COG0086@2|Bacteria,46S79@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
TH3_k127_5881676_1	671143.DAMO_0532	0.0	1347.0	COG0085@1|root,COG0085@2|Bacteria,2NNM9@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
TH3_k127_5881676_14	1121354.AQUV01000002_gene956	1.621e-18	87.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,22N5E@1653|Corynebacteriaceae	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
TH3_k127_5898082_9	580331.Thit_1828	4.309e-25	120.0	COG3225@1|root,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia,42FP0@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM ABC-type uncharacterised transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3,ABC_transp_aux
TH3_k127_5898082_8	497964.CfE428DRAFT_2297	4.94e-35	154.0	2DN50@1|root,32VJ4@2|Bacteria,46V62@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
TH3_k127_5898082_12	1485544.JQKP01000003_gene284	3.328e-09	71.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2VI5J@28216|Betaproteobacteria,44W58@713636|Nitrosomonadales	28216|Betaproteobacteria	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
TH3_k127_5898082_4	716928.AJQT01000101_gene335	3.145e-91	311.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2TSXG@28211|Alphaproteobacteria,4B993@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	gluconolactonase	-	-	3.1.1.17	ko:K01053,ko:K14274	ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02427,R02933,R03751	RC00537,RC00713,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
TH3_k127_5898082_0	1123242.JH636434_gene4856	1.393e-201	642.0	COG0591@1|root,COG0591@2|Bacteria,2J2KC@203682|Planctomycetes	203682|Planctomycetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
TH3_k127_5898082_2	497964.CfE428DRAFT_2419	4.99e-125	406.0	COG2084@1|root,COG2084@2|Bacteria,46S95@74201|Verrucomicrobia	74201|Verrucomicrobia	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
TH3_k127_5898082_11	1128912.GMES_3098	3.512e-10	70.0	COG3537@1|root,COG3537@2|Bacteria,1R4VD@1224|Proteobacteria,1RZJ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
TH3_k127_5898082_7	497964.CfE428DRAFT_5396	4.82e-36	142.0	2DQE3@1|root,3368V@2|Bacteria,46WIA@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5898082_10	1403819.BATR01000033_gene1102	1.742e-15	80.0	COG1526@1|root,COG1526@2|Bacteria,46SPA@74201|Verrucomicrobia,2IUBY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	FdhD/NarQ family	-	-	-	-	-	-	-	-	-	-	-	-	FdhD-NarQ
TH3_k127_5898082_5	1396141.BATP01000006_gene5486	3.635e-62	216.0	2DHFW@1|root,2ZZKM@2|Bacteria,46SNY@74201|Verrucomicrobia,2IVW8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5898082_1	497964.CfE428DRAFT_2417	5.361e-162	517.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
TH3_k127_5898082_3	583355.Caka_1932	8.481e-100	338.0	COG4398@1|root,COG4398@2|Bacteria,46SM5@74201|Verrucomicrobia	74201|Verrucomicrobia	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
TH3_k127_5898082_6	1122604.JONR01000006_gene2730	4.354e-53	193.0	COG0494@1|root,COG0494@2|Bacteria,1RI3B@1224|Proteobacteria,1S6HR@1236|Gammaproteobacteria,1X60F@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA mismatch repair protein MutT	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
TH3_k127_5917671_0	65093.PCC7418_0570	1.176e-126	454.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Pesticin,RHS_repeat
TH3_k127_5921981_2	886293.Sinac_3469	1.255e-104	348.0	COG1506@1|root,COG1506@2|Bacteria,2IXED@203682|Planctomycetes	203682|Planctomycetes	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
TH3_k127_5921981_1	1056820.KB900681_gene2859	4.861e-126	414.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,1RMHK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
TH3_k127_5921981_0	243231.GSU2762	2.238e-194	613.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,42M9Z@68525|delta/epsilon subdivisions,2WIYZ@28221|Deltaproteobacteria,43U0G@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
TH3_k127_5977898_0	1121472.AQWN01000001_gene77	3.983e-251	790.0	COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,248A6@186801|Clostridia,2610J@186807|Peptococcaceae	186801|Clostridia	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
TH3_k127_5977898_6	497964.CfE428DRAFT_3542	1.321e-109	360.0	COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria,46TXQ@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
TH3_k127_5977898_12	497964.CfE428DRAFT_0420	1.054e-42	159.0	2AY99@1|root,31QBJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5977898_14	765912.Thimo_1502	6.379e-38	151.0	COG1833@1|root,COG1833@2|Bacteria,1QMZ1@1224|Proteobacteria,1TKAF@1236|Gammaproteobacteria,1X16M@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function DUF123	-	-	-	-	-	-	-	-	-	-	-	-	DUF123
TH3_k127_5977898_15	583355.Caka_1169	9.932e-38	152.0	COG1961@1|root,COG1961@2|Bacteria,46WTV@74201|Verrucomicrobia,3K8IR@414999|Opitutae	414999|Opitutae	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TH3_k127_5977898_7	234267.Acid_6003	2.08e-78	287.0	COG2251@1|root,COG3316@1|root,COG2251@2|Bacteria,COG3316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,DDE_Tnp_IS66,HHH_5,RNase_H_2
TH3_k127_5977898_22	118161.KB235918_gene5	9.142e-10	63.0	2DTC9@1|root,33JP3@2|Bacteria,1GB2W@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5977898_5	237368.SCABRO_01787	8.055e-132	438.0	COG2963@1|root,COG3335@1|root,COG2963@2|Bacteria,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_28,HTH_Tnp_1
TH3_k127_5977898_18	1173023.KE650771_gene588	1.074e-17	84.0	COG2442@1|root,COG2442@2|Bacteria,1G9FC@1117|Cyanobacteria,1JMBK@1189|Stigonemataceae	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
TH3_k127_5977898_21	1173263.Syn7502_01724	1.218e-10	66.0	COG4634@1|root,COG4634@2|Bacteria,1GA41@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5977898_10	575540.Isop_1515	4.296e-45	176.0	COG1975@1|root,COG1975@2|Bacteria,2IXRN@203682|Planctomycetes	203682|Planctomycetes	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
TH3_k127_5977898_9	292563.Cyast_2134	1.998e-59	214.0	COG0642@1|root,COG2205@2|Bacteria,1G3D2@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c
TH3_k127_5977898_2	382464.ABSI01000010_gene3622	7.133e-218	699.0	COG0551@1|root,COG0551@2|Bacteria,46SJD@74201|Verrucomicrobia,2IVAK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
TH3_k127_5977898_3	382464.ABSI01000010_gene3621	1.047e-191	608.0	COG2960@1|root,COG2960@2|Bacteria,46UCE@74201|Verrucomicrobia,2IVAW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
TH3_k127_5977898_4	935863.AWZR01000001_gene1970	2.697e-137	445.0	COG2382@1|root,COG2382@2|Bacteria,1NFUS@1224|Proteobacteria,1T816@1236|Gammaproteobacteria,1XA10@135614|Xanthomonadales	135614|Xanthomonadales	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
TH3_k127_5977898_11	497964.CfE428DRAFT_3172	1.796e-44	166.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yitI	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
TH3_k127_5977898_19	794903.OPIT5_14770	5.094e-14	82.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_5977898_8	298654.FraEuI1c_4826	2.308e-61	230.0	COG2234@1|root,COG2234@2|Bacteria,2GJ67@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
TH3_k127_5977898_13	497964.CfE428DRAFT_3867	4.414e-42	156.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	2.7.7.80,2.8.1.11	ko:K03636,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiS
TH3_k127_5977898_1	330214.NIDE3482	7.66e-220	687.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
TH3_k127_5977898_20	246200.SPO0022	4.509e-13	76.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1N4K5@1224|Proteobacteria,2TS77@28211|Alphaproteobacteria,4N9Z4@97050|Ruegeria	28211|Alphaproteobacteria	T	response regulator	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HATPase_c_2,Response_reg,SpoIIE
TH3_k127_5984815_4	452637.Oter_0816	1.849e-183	578.0	COG1350@1|root,COG1350@2|Bacteria	2|Bacteria	E	tryptophan synthase activity	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TH3_k127_5984815_11	1265505.ATUG01000001_gene3993	1.656e-63	229.0	COG4313@1|root,COG4313@2|Bacteria,1R6GU@1224|Proteobacteria,43BI4@68525|delta/epsilon subdivisions,2X6WJ@28221|Deltaproteobacteria,2MKN8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
TH3_k127_5984815_5	886293.Sinac_0364	3.217e-164	532.0	COG0388@1|root,COG0388@2|Bacteria,2IXSE@203682|Planctomycetes	203682|Planctomycetes	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
TH3_k127_5984815_9	1267535.KB906767_gene1663	1.82e-88	316.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF5011,SLH
TH3_k127_5984815_6	1274374.CBLK010000061_gene596	5.208e-115	382.0	2CAEK@1|root,2ZCPG@2|Bacteria,1U07Z@1239|Firmicutes,4I9IQ@91061|Bacilli,271MJ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5984815_8	1123242.JH636435_gene2066	1.555e-112	390.0	COG2366@1|root,COG2366@2|Bacteria,2J08A@203682|Planctomycetes	203682|Planctomycetes	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
TH3_k127_5984815_2	497964.CfE428DRAFT_5897	1.421e-225	724.0	COG1073@1|root,COG1073@2|Bacteria,46TMQ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5984815_10	502025.Hoch_2530	8.318e-75	265.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,42MPE@68525|delta/epsilon subdivisions,2X630@28221|Deltaproteobacteria,2Z38I@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
TH3_k127_5984815_0	502025.Hoch_2529	0.0	1187.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
TH3_k127_5984815_1	502025.Hoch_2528	3.206e-311	988.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
TH3_k127_5984815_3	452637.Oter_2196	1.734e-187	595.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_5984815_7	504472.Slin_2839	5.567e-115	385.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,47M0H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_5984978_2	1469557.JSWF01000032_gene3224	2.188e-19	100.0	COG2304@1|root,COG3537@1|root,COG4935@1|root,COG2304@2|Bacteria,COG3537@2|Bacteria,COG4935@2|Bacteria,4PPWI@976|Bacteroidetes,1IKWA@117743|Flavobacteriia	976|Bacteroidetes	G	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_5984978_0	1396141.BATP01000003_gene4934	3.544e-42	169.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
TH3_k127_5984978_1	485918.Cpin_7074	5.255e-38	164.0	COG3115@1|root,COG3115@2|Bacteria,4PN8V@976|Bacteroidetes,1J0PP@117747|Sphingobacteriia	976|Bacteroidetes	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6012889_3	452637.Oter_0135	4.037e-275	859.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,3K7PT@414999|Opitutae	74201|Verrucomicrobia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
TH3_k127_6012889_40	316274.Haur_2251	4.158e-31	144.0	COG1629@1|root,COG3055@1|root,COG1629@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Kelch_1,Plug
TH3_k127_6012889_51	522373.Smlt0682	3.008e-11	74.0	COG3325@1|root,COG3325@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,1X5BZ@135614|Xanthomonadales	135614|Xanthomonadales	G	chitinase	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Calx-beta,Glyco_hydro_18,fn3
TH3_k127_6012889_7	1396418.BATQ01000014_gene4352	1.511e-152	490.0	COG3616@1|root,COG3616@2|Bacteria,46TAP@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
TH3_k127_6012889_50	661478.OP10G_4802	4.2e-12	76.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_6012889_0	886293.Sinac_6957	0.0	1206.0	COG2010@1|root,COG2010@2|Bacteria,2J2GM@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
TH3_k127_6012889_53	504487.JCM19302_1724	1.174e-07	59.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,1I40W@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TH3_k127_6012889_4	886293.Sinac_6958	7.285e-248	771.0	COG1524@1|root,COG1524@2|Bacteria,2J563@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TH3_k127_6012889_14	886293.Sinac_4427	7.129e-108	360.0	COG3023@1|root,COG3023@2|Bacteria,2J257@203682|Planctomycetes	203682|Planctomycetes	V	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
TH3_k127_6012889_21	521674.Plim_0037	1.817e-92	320.0	COG0673@1|root,COG0673@2|Bacteria,2IXFW@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_6012889_11	497964.CfE428DRAFT_1395	2.938e-131	446.0	COG1262@1|root,COG1262@2|Bacteria,46UX3@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PSCyt1
TH3_k127_6012889_57	497964.CfE428DRAFT_0660	0.0007884	49.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1542,DUF349,DUF4446,FIVAR,GA,Gram_pos_anchor,PhageMin_Tail
TH3_k127_6012889_35	1156937.MFUM_270037	4.083e-51	194.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,46SYU@74201|Verrucomicrobia,37GE7@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Outer membrane lipoprotein	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_16,TPR_6,YfiO
TH3_k127_6012889_49	497964.CfE428DRAFT_3831	1.861e-16	88.0	2EM72@1|root,33EW9@2|Bacteria,46TAB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
TH3_k127_6012889_43	497964.CfE428DRAFT_4502	6.107e-27	114.0	COG0607@1|root,COG0607@2|Bacteria,46W9V@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TH3_k127_6012889_32	497964.CfE428DRAFT_3997	1.902e-62	227.0	COG0515@1|root,COG0515@2|Bacteria,46TX9@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RicinB_lectin_2
TH3_k127_6012889_30	435832.HMPREF0604_01422	1.103e-67	239.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,2KPMA@206351|Neisseriales	206351|Neisseriales	KLT	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
TH3_k127_6012889_20	861299.J421_5600	1.999e-94	321.0	COG1172@1|root,COG1172@2|Bacteria,1ZUX9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440,ko:K10553	ko02010,map02010	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	BPD_transp_2
TH3_k127_6012889_12	861299.J421_5609	2.297e-115	380.0	COG1879@1|root,COG1879@2|Bacteria,1ZV3Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K10439,ko:K10552	ko02010,ko02030,map02010,map02030	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	Peripla_BP_4
TH3_k127_6012889_56	1150469.RSPPHO_02781	0.0005539	47.0	COG2165@1|root,COG2165@2|Bacteria,1PJ5F@1224|Proteobacteria,2VC7I@28211|Alphaproteobacteria,2JY2W@204441|Rhodospirillales	204441|Rhodospirillales	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6012889_17	452637.Oter_1518	1.817e-102	346.0	2BYUR@1|root,32TV8@2|Bacteria,46V5C@74201|Verrucomicrobia,3K7PA@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6012889_46	234267.Acid_7793	6.379e-24	103.0	COG1598@1|root,COG1598@2|Bacteria,3Y5U6@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6012889_48	13035.Dacsa_0245	7.747e-17	81.0	COG1724@1|root,COG1724@2|Bacteria,1G8WI@1117|Cyanobacteria	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
TH3_k127_6012889_47	926569.ANT_11850	5.984e-20	95.0	COG0784@1|root,COG0784@2|Bacteria,2GBNB@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
TH3_k127_6012889_23	583355.Caka_0017	1.948e-82	281.0	COG3880@1|root,COG3880@2|Bacteria,46SMN@74201|Verrucomicrobia,3K7MX@414999|Opitutae	414999|Opitutae	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
TH3_k127_6012889_1	452637.Oter_3934	0.0	1033.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,3K7GM@414999|Opitutae	414999|Opitutae	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
TH3_k127_6012889_6	278957.ABEA03000189_gene958	6.083e-212	667.0	COG5557@1|root,COG5557@2|Bacteria,46S9S@74201|Verrucomicrobia,3K751@414999|Opitutae	414999|Opitutae	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
TH3_k127_6012889_33	794903.OPIT5_22590	2.684e-60	214.0	COG2010@1|root,COG2010@2|Bacteria,46V1P@74201|Verrucomicrobia,3K7WS@414999|Opitutae	414999|Opitutae	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
TH3_k127_6012889_36	794903.OPIT5_22595	6.059e-42	163.0	COG2010@1|root,COG2010@2|Bacteria,46SV4@74201|Verrucomicrobia,3K7Z7@414999|Opitutae	414999|Opitutae	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
TH3_k127_6012889_29	452637.Oter_3930	6.78e-69	250.0	COG4531@1|root,COG4531@2|Bacteria,46SME@74201|Verrucomicrobia,3K79U@414999|Opitutae	414999|Opitutae	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6012889_55	452637.Oter_3929	0.000182	49.0	2B8Q9@1|root,321ZW@2|Bacteria,46XX6@74201|Verrucomicrobia,3K8IF@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6012889_22	794903.OPIT5_22615	1.694e-90	316.0	COG3278@1|root,COG3278@2|Bacteria,46T64@74201|Verrucomicrobia,3K7FT@414999|Opitutae	414999|Opitutae	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
TH3_k127_6012889_38	1123508.JH636443_gene5054	7.764e-36	151.0	COG2993@1|root,COG2993@2|Bacteria,2IZNM@203682|Planctomycetes	203682|Planctomycetes	C	COGs COG2993 Cbb3-type cytochrome oxidase cytochrome c subunit	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
TH3_k127_6012889_44	1288963.ADIS_1441	5.395e-25	112.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG2755@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,4NEQA@976|Bacteroidetes,47MTS@768503|Cytophagia	976|Bacteroidetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,HEAT_2,Lipase_GDSL_2
TH3_k127_6012889_5	1123242.JH636434_gene4686	2.4e-223	701.0	COG3119@1|root,COG3119@2|Bacteria,2IX1H@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TH3_k127_6012889_2	886293.Sinac_7111	5.4e-323	1023.0	COG2010@1|root,COG2010@2|Bacteria,2IYDW@203682|Planctomycetes	203682|Planctomycetes	C	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
TH3_k127_6012889_9	1123508.JH636449_gene7418	1.929e-145	477.0	COG1680@1|root,COG1680@2|Bacteria,2J0ZW@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TH3_k127_6012889_26	1227360.C176_13277	6.555e-76	284.0	COG2366@1|root,COG2366@2|Bacteria,1UFHA@1239|Firmicutes,4HACM@91061|Bacilli,26EP7@186818|Planococcaceae	91061|Bacilli	S	Penicillin acylase	acyII	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
TH3_k127_6012889_10	886293.Sinac_6493	1.559e-144	482.0	COG0501@1|root,COG0501@2|Bacteria,2IYND@203682|Planctomycetes	203682|Planctomycetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TH3_k127_6012889_39	999419.HMPREF1077_03046	1.236e-35	149.0	COG2303@1|root,COG2303@2|Bacteria,4PKTW@976|Bacteroidetes,2FS8M@200643|Bacteroidia,22XM0@171551|Porphyromonadaceae	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_6012889_18	1403819.BATR01000120_gene4250	1.711e-99	342.0	COG0477@1|root,COG2814@2|Bacteria,46V8K@74201|Verrucomicrobia,2IUV3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
TH3_k127_6012889_31	1121440.AUMA01000008_gene860	7.98e-66	240.0	COG1835@1|root,COG1835@2|Bacteria,1MYXY@1224|Proteobacteria,42VFT@68525|delta/epsilon subdivisions,2WRGM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TH3_k127_6012889_24	497964.CfE428DRAFT_5265	2.38e-80	282.0	2E1EI@1|root,32WTG@2|Bacteria,46T04@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6012889_15	661478.OP10G_3197	3.823e-106	365.0	28MB8@1|root,2ZAPS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6012889_8	497964.CfE428DRAFT_2917	6.833e-149	483.0	COG0015@1|root,COG0015@2|Bacteria,46UUE@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Adenylosuccinate lyase C-terminus	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
TH3_k127_6012889_28	1304872.JAGC01000005_gene2041	4.908e-72	259.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42NHG@68525|delta/epsilon subdivisions,2WKFP@28221|Deltaproteobacteria,2M7SS@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE
TH3_k127_6012889_34	1499967.BAYZ01000089_gene5033	6.298e-54	200.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TH3_k127_6012889_37	1396418.BATQ01000046_gene6161	3.968e-41	164.0	COG0705@1|root,COG0705@2|Bacteria,46W15@74201|Verrucomicrobia,2IUFI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TH3_k127_6012889_27	1303518.CCALI_00781	4.474e-73	258.0	COG1477@1|root,COG1477@2|Bacteria	2|Bacteria	H	protein flavinylation	apbE_1	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
TH3_k127_6012889_25	1303518.CCALI_00782	2.112e-78	279.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
TH3_k127_6012889_16	1122605.KB893625_gene1943	6.908e-105	356.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,1IUUU@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TH3_k127_6012889_42	999541.bgla_1g01550	3.714e-27	130.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria,2WI8K@28216|Betaproteobacteria,1KIR6@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Domain of unknown function (DUF4982)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set
TH3_k127_6012889_52	349521.HCH_01827	8.858e-08	66.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_6012889_19	402777.KB235903_gene2334	2.387e-96	355.0	COG1649@1|root,COG1649@2|Bacteria,1G42C@1117|Cyanobacteria,1H72B@1150|Oscillatoriales	1117|Cyanobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
TH3_k127_6012889_54	382464.ABSI01000020_gene148	6.704e-07	57.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
TH3_k127_6012889_13	269797.Mbar_A1995	9.821e-115	387.0	arCOG02516@1|root,arCOG02538@1|root,arCOG02516@2157|Archaea,arCOG02538@2157|Archaea,2Y7RK@28890|Euryarchaeota,2NBKX@224756|Methanomicrobia	2157|Archaea	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,He_PIG,PKD,PQQ_3,Peptidase_S8,S-layer
TH3_k127_6013539_4	1123508.JH636441_gene3137	1.712e-08	57.0	COG2165@1|root,COG2165@2|Bacteria,2IZ0K@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_6013539_3	344747.PM8797T_28619	1.158e-09	67.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_6013539_1	521674.Plim_3726	4.17e-13	81.0	COG2165@1|root,COG2165@2|Bacteria,2IYN2@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_6013539_6	1123242.JH636434_gene5550	4.437e-07	60.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_6013539_0	1403819.BATR01000195_gene6595	5.929e-33	133.0	COG5421@1|root,COG5421@2|Bacteria,46U8B@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
TH3_k127_6013539_2	671143.DAMO_1369	4.27e-10	70.0	COG0204@1|root,COG0204@2|Bacteria,2NPW3@2323|unclassified Bacteria	2|Bacteria	I	Phosphate acyltransferases	cmk	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TH3_k127_6013539_5	1254432.SCE1572_41060	3.559e-07	58.0	COG3049@1|root,COG3049@2|Bacteria,1RHU2@1224|Proteobacteria,42XVE@68525|delta/epsilon subdivisions,2WT93@28221|Deltaproteobacteria,2YW4E@29|Myxococcales	28221|Deltaproteobacteria	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
TH3_k127_6038960_2	485918.Cpin_6800	2.453e-20	91.0	COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes,1IRB5@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
TH3_k127_6038960_0	1123278.KB893574_gene6157	2.99e-192	623.0	COG3525@1|root,COG3525@2|Bacteria,4NH5U@976|Bacteroidetes,47R5K@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase, family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20b
TH3_k127_6038960_3	240016.ABIZ01000001_gene4411	1.031e-14	82.0	COG2755@1|root,COG2755@2|Bacteria,46S6X@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Acyl-CoA thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TH3_k127_6038960_1	1492737.FEM08_16470	3.13e-91	307.0	COG1680@1|root,COG1680@2|Bacteria,4P506@976|Bacteroidetes	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6055678_1	240016.ABIZ01000001_gene2641	3.595e-33	130.0	COG4842@1|root,COG4842@2|Bacteria,46VM0@74201|Verrucomicrobia,2IVW9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Proteins of 100 residues with WXG	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
TH3_k127_6055678_2	497964.CfE428DRAFT_3534	3.442e-29	126.0	2ET52@1|root,33KP5@2|Bacteria,46VY7@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6055678_3	240016.ABIZ01000001_gene2639	2.219e-05	50.0	2DD5J@1|root,2ZGMA@2|Bacteria,46WYE@74201|Verrucomicrobia,2IWBI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6055678_0	1396418.BATQ01000117_gene4542	1.979e-90	323.0	COG1674@1|root,COG1674@2|Bacteria,46V0I@74201|Verrucomicrobia,2IVES@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	FtsK/SpoIIIE family	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
TH3_k127_6067621_2	509635.N824_25535	5.276e-28	114.0	COG3828@1|root,COG3828@2|Bacteria,4NKKG@976|Bacteroidetes	976|Bacteroidetes	S	Glycosyl hydrolase family 99	-	-	3.2.1.130,3.2.1.198	ko:K21132	-	-	-	-	ko00000,ko01000	-	GH99	-	Glyco_hydro_99
TH3_k127_6067621_0	595460.RRSWK_00087	1.074e-172	566.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_42,Glyco_hydro_42M
TH3_k127_6067621_1	509635.N824_15295	8.925e-123	420.0	2DBGI@1|root,2Z94U@2|Bacteria,4NI4P@976|Bacteroidetes,1IVFE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_611276_1	357808.RoseRS_2969	5.707e-162	518.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi,3755G@32061|Chloroflexia	32061|Chloroflexia	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
TH3_k127_611276_0	1121468.AUBR01000038_gene1965	1.744e-259	823.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,247RR@186801|Clostridia,42HW6@68295|Thermoanaerobacterales	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
TH3_k127_6129605_27	794903.OPIT5_23905	2.604e-09	67.0	COG2165@1|root,COG2165@2|Bacteria,46Z9G@74201|Verrucomicrobia,3K9NR@414999|Opitutae	2|Bacteria	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_6129605_22	1121904.ARBP01000033_gene3213	5.317e-31	135.0	28K60@1|root,2Z9UH@2|Bacteria,4NHE6@976|Bacteroidetes,47UNS@768503|Cytophagia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
TH3_k127_6129605_20	1168034.FH5T_12675	4.758e-46	178.0	2CI12@1|root,338T1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6129605_8	240016.ABIZ01000001_gene4539	3.135e-140	465.0	COG0621@1|root,COG0621@2|Bacteria,46S5U@74201|Verrucomicrobia,2ITS9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Uncharacterized protein family UPF0004	-	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
TH3_k127_6129605_21	903814.ELI_2067	2.306e-38	151.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,25W8B@186806|Eubacteriaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
TH3_k127_6129605_25	1123267.JONN01000001_gene1815	7.056e-11	69.0	COG1426@1|root,COG1426@2|Bacteria,1ND8D@1224|Proteobacteria,2UB49@28211|Alphaproteobacteria,2K57P@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
TH3_k127_6129605_3	1210884.HG799462_gene7951	1.426e-233	730.0	COG4102@1|root,COG4102@2|Bacteria,2IX5T@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TH3_k127_6129605_0	497964.CfE428DRAFT_2433	0.0	1182.0	COG2010@1|root,COG4654@1|root,COG2010@2|Bacteria,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
TH3_k127_6129605_2	497964.CfE428DRAFT_3528	6.219e-255	792.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501,Laminin_G_3
TH3_k127_6129605_1	886293.Sinac_3371	2.344e-287	915.0	COG2010@1|root,COG2010@2|Bacteria,2IYIY@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
TH3_k127_6129605_18	497964.CfE428DRAFT_0110	3.554e-56	200.0	COG1595@1|root,COG1595@2|Bacteria,46VNT@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TH3_k127_6129605_14	497964.CfE428DRAFT_0111	1.057e-65	247.0	2CMJG@1|root,32SEZ@2|Bacteria,46T0G@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6129605_11	1123288.SOV_3c03730	3.334e-78	271.0	COG1043@1|root,COG1043@2|Bacteria,1TQRI@1239|Firmicutes,4H2NG@909932|Negativicutes	909932|Negativicutes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep,Hexapep_2
TH3_k127_6129605_7	240016.ABIZ01000001_gene4595	2.67e-147	481.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,46SG1@74201|Verrucomicrobia,2ITYH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
TH3_k127_6129605_19	452637.Oter_0798	2.967e-52	197.0	COG0741@1|root,COG0741@2|Bacteria,46XU1@74201|Verrucomicrobia,3K83P@414999|Opitutae	414999|Opitutae	M	Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SLT
TH3_k127_6129605_16	935845.JADQ01000029_gene1230	1.181e-63	240.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
TH3_k127_6129605_24	1288494.EBAPG3_19800	1.698e-18	89.0	COG1216@1|root,COG1216@2|Bacteria,1N5DV@1224|Proteobacteria,2WB4B@28216|Betaproteobacteria,372A6@32003|Nitrosomonadales	28216|Betaproteobacteria	S	glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TH3_k127_6129605_26	338963.Pcar_1313	1.103e-10	76.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions,2WJR1@28221|Deltaproteobacteria,43S2F@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2,DUF748
TH3_k127_6129605_4	1396141.BATP01000030_gene3746	4.185e-228	717.0	COG1129@1|root,COG1129@2|Bacteria,46SG6@74201|Verrucomicrobia,2IV5X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
TH3_k127_6129605_9	497964.CfE428DRAFT_3050	2.634e-130	424.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10560	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2
TH3_k127_6129605_5	497964.CfE428DRAFT_3049	1.484e-157	502.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10559,ko:K10561	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2,Peripla_BP_4
TH3_k127_6129605_28	28072.Nos7524_5534	9.837e-06	56.0	COG3511@1|root,COG3511@2|Bacteria,1GHGK@1117|Cyanobacteria,1HRDE@1161|Nostocales	1117|Cyanobacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6129605_13	1396141.BATP01000060_gene4563	2.293e-68	252.0	COG0457@1|root,COG0457@2|Bacteria,46W3Y@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16
TH3_k127_6129605_6	497964.CfE428DRAFT_3048	6.389e-155	500.0	COG1879@1|root,COG1879@2|Bacteria,46TWY@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
TH3_k127_6129605_29	497964.CfE428DRAFT_5353	0.0009163	43.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
TH3_k127_6129605_17	886293.Sinac_0846	8.822e-63	228.0	COG0310@1|root,COG0310@2|Bacteria,2IZTS@203682|Planctomycetes	203682|Planctomycetes	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
TH3_k127_6129605_23	675635.Psed_3353	8.258e-22	103.0	COG0619@1|root,COG0619@2|Bacteria,2GKQ7@201174|Actinobacteria,4E0T6@85010|Pseudonocardiales	201174|Actinobacteria	P	Cobalt transport protein	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
TH3_k127_6129605_12	886293.Sinac_0844	1.294e-73	255.0	COG1122@1|root,COG1122@2|Bacteria,2IZ47@203682|Planctomycetes	203682|Planctomycetes	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	-	-	-	ko:K02006,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
TH3_k127_6129605_10	452637.Oter_1576	8.09e-86	295.0	COG0598@1|root,COG0598@2|Bacteria,46VYH@74201|Verrucomicrobia,3K7J8@414999|Opitutae	414999|Opitutae	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
TH3_k127_6129605_15	478741.JAFS01000002_gene392	3.976e-65	235.0	COG5000@1|root,COG5000@2|Bacteria,46S9Q@74201|Verrucomicrobia,37FXN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	PAS domain	ntrB	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
TH3_k127_6134399_2	1123242.JH636434_gene4299	6.411e-76	272.0	COG2755@1|root,COG2755@2|Bacteria,2IZUG@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TH3_k127_6134399_9	1118059.CAHC01000003_gene959	2.304e-08	63.0	COG0507@1|root,COG0507@2|Bacteria,1V27I@1239|Firmicutes,24GPP@186801|Clostridia	186801|Clostridia	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6134399_8	926556.Echvi_3203	1.785e-18	91.0	COG3385@1|root,COG5421@1|root,COG3385@2|Bacteria,COG5421@2|Bacteria,4NXT2@976|Bacteroidetes	976|Bacteroidetes	L	hmm pf01609	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
TH3_k127_6134399_11	497964.CfE428DRAFT_0066	2.095e-06	50.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
TH3_k127_6134399_3	686340.Metal_3113	9.677e-75	292.0	COG3291@1|root,COG3291@2|Bacteria,1R7A1@1224|Proteobacteria,1S0A9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IgGFc_binding
TH3_k127_6134399_4	1430440.MGMSRv2_2439	2.143e-64	258.0	COG1520@1|root,COG1520@2|Bacteria,1QV8R@1224|Proteobacteria	1224|Proteobacteria	G	6-phosphogluconolactonase activity	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,DUF4347,HYR,VCBS
TH3_k127_6134399_12	867845.KI911784_gene210	4.624e-05	61.0	COG3391@1|root,COG3391@2|Bacteria,2GBRT@200795|Chloroflexi,376BG@32061|Chloroflexia	32061|Chloroflexia	S	PA14	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PA14
TH3_k127_6134399_10	1502851.FG93_00043	1.316e-06	66.0	COG1404@1|root,COG2931@1|root,COG4932@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1QYHZ@1224|Proteobacteria,2UHT4@28211|Alphaproteobacteria,3K04W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
TH3_k127_6134399_5	856793.MICA_147	1.667e-52	218.0	COG1520@1|root,COG1520@2|Bacteria,1R0E4@1224|Proteobacteria,2UJBQ@28211|Alphaproteobacteria,4BSD7@82117|unclassified Alphaproteobacteria	1224|Proteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
TH3_k127_6134399_1	99598.Cal7507_3395	3.244e-97	366.0	COG1520@1|root,COG1520@2|Bacteria,1GHEB@1117|Cyanobacteria,1HKIG@1161|Nostocales	1117|Cyanobacteria	C	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	PPC
TH3_k127_6134399_7	1100720.ALKN01000002_gene1847	4.654e-27	134.0	COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	3.1.4.50	ko:K01127	ko00563,map00563	-	R06623	-	ko00000,ko00001,ko01000	-	-	-	Big_5,Calx-beta,FG-GAP,HemolysinCabind
TH3_k127_6134399_6	203124.Tery_0117	1.855e-31	148.0	COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1G04D@1117|Cyanobacteria,1H779@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,Peptidase_S8,SdrD_B
TH3_k127_6134399_0	595460.RRSWK_02125	0.0	1319.0	COG1357@1|root,COG1511@1|root,COG2931@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1511@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,2IZ0P@203682|Planctomycetes	203682|Planctomycetes	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Laminin_G_3
TH3_k127_6149943_0	1396141.BATP01000057_gene3053	3.377e-157	535.0	COG2312@1|root,COG3209@1|root,COG2312@2|Bacteria,COG3209@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
TH3_k127_6149943_1	886293.Sinac_0289	2.158e-22	100.0	COG3293@1|root,COG3293@2|Bacteria,2IY34@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
TH3_k127_6149943_2	756272.Plabr_1230	7.412e-09	60.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_6161939_6	497964.CfE428DRAFT_3032	4.021e-194	615.0	COG1109@1|root,COG1109@2|Bacteria,46SJ2@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TH3_k127_6161939_17	530564.Psta_1104	9.099e-14	71.0	COG4912@1|root,COG4912@2|Bacteria,2IZ0C@203682|Planctomycetes	203682|Planctomycetes	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
TH3_k127_6161939_20	344747.PM8797T_25341	0.0007936	44.0	COG4912@1|root,COG4912@2|Bacteria,2IZ0C@203682|Planctomycetes	203682|Planctomycetes	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
TH3_k127_6161939_16	1396418.BATQ01000135_gene3650	5.53e-31	133.0	COG2165@1|root,COG2165@2|Bacteria,46W6U@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
TH3_k127_6161939_9	452637.Oter_1502	3.465e-104	349.0	COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,3K7BH@414999|Opitutae	2|Bacteria	V	PFAM ABC transporter related	ecsA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_6161939_10	452637.Oter_1501	1.833e-103	358.0	29YN3@1|root,30KHK@2|Bacteria	2|Bacteria	S	Putative ABC exporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_export
TH3_k127_6161939_14	314230.DSM3645_26609	5.076e-56	204.0	COG2010@1|root,COG2133@1|root,COG3828@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IYH1@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Cytochrom_C,Cytochrome_CBB3,Laminin_G_3,ThuA
TH3_k127_6161939_8	344747.PM8797T_15161	4.952e-112	377.0	COG0673@1|root,COG0673@2|Bacteria,2IXE4@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_6161939_5	497964.CfE428DRAFT_2506	3.623e-246	765.0	COG0065@1|root,COG0065@2|Bacteria,46SUM@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
TH3_k127_6161939_0	1396141.BATP01000040_gene2167	0.0	1328.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,46TRH@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Tricorn protease PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
TH3_k127_6161939_13	530564.Psta_3458	6.374e-70	251.0	COG1416@1|root,COG4798@1|root,COG1416@2|Bacteria,COG4798@2|Bacteria,2IZ87@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,Methyltransf_25
TH3_k127_6161939_12	1287276.X752_02890	1.173e-87	302.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2UQQC@28211|Alphaproteobacteria,43N9M@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
TH3_k127_6161939_1	886293.Sinac_7498	3.333e-312	991.0	COG2010@1|root,COG2010@2|Bacteria,2IXZ4@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
TH3_k127_6161939_4	886293.Sinac_7494	4.692e-254	791.0	COG4102@1|root,COG4102@2|Bacteria,2IXKR@203682|Planctomycetes	203682|Planctomycetes	T	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TH3_k127_6161939_15	1235803.C825_05233	2.512e-33	150.0	2CHVP@1|root,2Z866@2|Bacteria,4NJWZ@976|Bacteroidetes,2FY0D@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6161939_11	639030.JHVA01000001_gene3738	5.836e-89	302.0	COG3836@1|root,COG3836@2|Bacteria,3Y5ZN@57723|Acidobacteria,2JKP5@204432|Acidobacteriia	204432|Acidobacteriia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
TH3_k127_6161939_2	234267.Acid_0200	1.692e-281	890.0	COG3661@1|root,COG3661@2|Bacteria,3Y3Q5@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the glycosyl hydrolase 67 family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6161939_3	1288963.ADIS_1157	4.743e-260	828.0	COG3292@1|root,COG3292@2|Bacteria,4P1XS@976|Bacteroidetes,47U9C@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6161939_7	401053.AciPR4_2231	5.009e-164	559.0	COG3250@1|root,COG3250@2|Bacteria,3Y62S@57723|Acidobacteria,2JM9E@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
TH3_k127_6161939_19	1550091.JROE01000008_gene3578	0.0004865	51.0	2DBF9@1|root,2Z8X9@2|Bacteria,4NHC2@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4434)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4434,DUF5109
TH3_k127_619802_1	886293.Sinac_0942	2.292e-47	181.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TH3_k127_619802_0	694427.Palpr_0584	3.73e-101	346.0	COG3534@1|root,COG3534@2|Bacteria,4NGKW@976|Bacteroidetes,2FM0F@200643|Bacteroidia,22WCS@171551|Porphyromonadaceae	976|Bacteroidetes	G	PFAM alpha-L-arabinofuranosidase domain protein	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
TH3_k127_6205839_1	1123392.AQWL01000008_gene1217	8.51e-15	79.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,2VQGY@28216|Betaproteobacteria,1KSKF@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
TH3_k127_6205839_0	335543.Sfum_1859	1.038e-212	684.0	28HUW@1|root,2Z81F@2|Bacteria,1Q3QA@1224|Proteobacteria,42Q50@68525|delta/epsilon subdivisions,2WJN7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6209761_1	240016.ABIZ01000001_gene4315	2.991e-182	591.0	COG1167@1|root,COG1167@2|Bacteria,46STK@74201|Verrucomicrobia,2IVDB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EK	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
TH3_k127_6209761_2	1403819.BATR01000069_gene2027	5.858e-158	506.0	COG2382@1|root,COG3693@1|root,COG2382@2|Bacteria,COG3693@2|Bacteria,46YZE@74201|Verrucomicrobia,2IU0Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
TH3_k127_6209761_0	234267.Acid_1336	2.321e-204	644.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
TH3_k127_6226578_2	452637.Oter_3269	1.405e-21	103.0	COG0457@1|root,COG3071@1|root,COG0457@2|Bacteria,COG3071@2|Bacteria,46VFP@74201|Verrucomicrobia,3K8RR@414999|Opitutae	414999|Opitutae	H	HemY protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6226578_1	118173.KB235914_gene3105	3.891e-40	160.0	COG0666@1|root,COG0666@2|Bacteria,1G0E1@1117|Cyanobacteria,1H7BV@1150|Oscillatoriales	1117|Cyanobacteria	S	COG0666 FOG Ankyrin repeat	ank	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
TH3_k127_6226578_0	234267.Acid_7728	4.809e-112	370.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
TH3_k127_6227390_2	1041522.MCOL_V214069	2.18e-201	653.0	COG1111@1|root,COG4889@1|root,COG1111@2|Bacteria,COG4889@2|Bacteria,2GKP2@201174|Actinobacteria,233SK@1762|Mycobacteriaceae	201174|Actinobacteria	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	HA,Helicase_C,Mrr_cat_2,N6_Mtase,ResIII
TH3_k127_6227390_15	1121013.P873_11445	6.444e-36	147.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,1SZQR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
TH3_k127_6227390_27	1120983.KB894574_gene1005	1.136e-14	79.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria,1JPHB@119043|Rhodobiaceae	28211|Alphaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
TH3_k127_6227390_21	1238450.VIBNISOn1_1470029	1.045e-28	128.0	COG3332@1|root,COG3332@2|Bacteria,1RE1W@1224|Proteobacteria,1S59Q@1236|Gammaproteobacteria,1XU3T@135623|Vibrionales	135623|Vibrionales	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
TH3_k127_6227390_5	1210884.HG799463_gene9621	6.845e-113	384.0	COG0189@1|root,COG0586@1|root,COG3332@1|root,COG0189@2|Bacteria,COG0586@2|Bacteria,COG3332@2|Bacteria	2|Bacteria	S	Transport and Golgi organisation 2	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	RimK,SNARE_assoc,TANGO2
TH3_k127_6227390_18	1123070.KB899257_gene2311	5.734e-33	134.0	COG2318@1|root,COG2318@2|Bacteria,46WF2@74201|Verrucomicrobia,2IWE9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6227390_16	929703.KE386491_gene4207	1.745e-35	139.0	2C87P@1|root,32H7J@2|Bacteria,4NS7S@976|Bacteroidetes,47R39@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
TH3_k127_6227390_17	1502851.FG93_03399	1.271e-34	139.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2UBRM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YHS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
TH3_k127_6227390_7	864702.OsccyDRAFT_4593	1.054e-95	321.0	COG0580@1|root,COG0580@2|Bacteria,1G3MJ@1117|Cyanobacteria,1H9H5@1150|Oscillatoriales	1117|Cyanobacteria	G	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
TH3_k127_6227390_23	1123278.KB893444_gene1666	5.527e-25	115.0	2C87P@1|root,32H7J@2|Bacteria,4NS7S@976|Bacteroidetes,47R39@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
TH3_k127_6227390_19	382464.ABSI01000012_gene2101	3.503e-32	143.0	COG0526@1|root,COG4935@1|root,COG0526@2|Bacteria,COG4935@2|Bacteria,46UYI@74201|Verrucomicrobia,2IWE7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TH3_k127_6227390_12	382464.ABSI01000010_gene3251	1.716e-41	164.0	COG0526@1|root,COG3210@1|root,COG0526@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Omp28
TH3_k127_6227390_10	452637.Oter_0302	8.817e-68	238.0	COG5429@1|root,COG5429@2|Bacteria,46W7J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
TH3_k127_6227390_24	1185653.A1A1_08864	3.554e-18	98.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,26EYU@186818|Planococcaceae	91061|Bacilli	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TH3_k127_6227390_31	344747.PM8797T_01589	4.057e-06	58.0	COG3266@1|root,COG3266@2|Bacteria,2IZW5@203682|Planctomycetes	203682|Planctomycetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6227390_3	861299.J421_1876	5.753e-184	594.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
TH3_k127_6227390_13	497964.CfE428DRAFT_5990	1.067e-38	153.0	COG1595@1|root,COG1595@2|Bacteria,46W20@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_6227390_26	1267534.KB906760_gene1563	9.717e-15	77.0	29A7N@1|root,2ZX8K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6227390_8	1396418.BATQ01000011_gene4474	1.909e-76	261.0	COG3576@1|root,COG3576@2|Bacteria,46SQM@74201|Verrucomicrobia,2IVR9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
TH3_k127_6227390_0	497964.CfE428DRAFT_5992	1.693e-294	923.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	ko:K15836	-	-	-	-	ko00000,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
TH3_k127_6227390_30	1230342.CTM_05128	1.647e-06	56.0	COG1145@1|root,32SB1@2|Bacteria,1V6N0@1239|Firmicutes,24M30@186801|Clostridia,36K6U@31979|Clostridiaceae	186801|Clostridia	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
TH3_k127_6227390_14	861299.J421_1875	1.216e-37	149.0	COG0662@1|root,COG3193@1|root,COG0662@2|Bacteria,COG3193@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Cupin_2,Haem_degrading
TH3_k127_6227390_22	1026882.MAMP_02169	9.978e-28	124.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,1S7V6@1236|Gammaproteobacteria,4633R@72273|Thiotrichales	72273|Thiotrichales	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
TH3_k127_6227390_20	1502851.FG93_03399	6.385e-29	128.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2UBRM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YHS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
TH3_k127_6227390_6	211165.AJLN01000061_gene3947	4.918e-112	373.0	COG0346@1|root,COG0346@2|Bacteria,1G29P@1117|Cyanobacteria,1JK2A@1189|Stigonemataceae	1117|Cyanobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TH3_k127_6227390_11	489825.LYNGBM3L_01300	5.286e-45	172.0	29EN4@1|root,301K2@2|Bacteria,1G4I6@1117|Cyanobacteria,1HET5@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6227390_4	504472.Slin_2526	5.12e-115	383.0	COG2146@1|root,COG2717@1|root,COG2146@2|Bacteria,COG2717@2|Bacteria,4NJUW@976|Bacteroidetes,47TAG@768503|Cytophagia	976|Bacteroidetes	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct,Rieske
TH3_k127_6227390_28	489825.LYNGBM3L_01330	4.952e-14	75.0	2E14K@1|root,32WJQ@2|Bacteria,1G825@1117|Cyanobacteria,1HGGM@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6227390_25	1077285.AGDG01000027_gene1673	4.877e-18	87.0	COG4828@1|root,COG4828@2|Bacteria,4NV5Z@976|Bacteroidetes,2G2GN@200643|Bacteroidia,4AVYR@815|Bacteroidaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
TH3_k127_6227390_9	1403819.BATR01000054_gene1700	1.246e-72	249.0	COG0431@1|root,COG0431@2|Bacteria,46SXE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
TH3_k127_6227390_1	211165.AJLN01000061_gene3942	1.036e-220	702.0	COG2303@1|root,COG2303@2|Bacteria,1G2DQ@1117|Cyanobacteria,1JHUA@1189|Stigonemataceae	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
TH3_k127_6227390_32	305700.B447_10758	0.0004922	51.0	2DU19@1|root,33NHC@2|Bacteria,1NKNM@1224|Proteobacteria,2VYQJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6227390_29	243233.MCA2830	3.253e-09	59.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
TH3_k127_6235104_10	292459.STH496	4.881e-28	119.0	COG1051@1|root,COG1051@2|Bacteria,1VHQV@1239|Firmicutes,24SJS@186801|Clostridia	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TH3_k127_6235104_9	1382359.JIAL01000001_gene1578	1.765e-91	307.0	COG0623@1|root,COG0623@2|Bacteria,3Y3EN@57723|Acidobacteria,2JHZZ@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TH3_k127_6235104_4	649638.Trad_2886	9.31e-160	519.0	COG1057@1|root,COG1057@2|Bacteria	2|Bacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18,3.6.1.55	ko:K00969,ko:K03574	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	CTP_transf_like
TH3_k127_6235104_3	1123242.JH636438_gene5875	1.853e-181	580.0	COG1520@1|root,COG1520@2|Bacteria,2IYNF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
TH3_k127_6235104_12	382464.ABSI01000013_gene1546	2.394e-23	110.0	COG5036@1|root,COG5036@2|Bacteria,46VA7@74201|Verrucomicrobia	74201|Verrucomicrobia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
TH3_k127_6235104_13	1144932.ATTF01000017_gene1171	6.651e-23	108.0	COG1285@1|root,COG1285@2|Bacteria,1PD3I@1224|Proteobacteria,2UKD1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
TH3_k127_6235104_21	414684.RC1_4050	0.0001759	53.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
TH3_k127_6235104_1	583355.Caka_3109	9.978e-224	759.0	COG2312@1|root,COG3507@1|root,COG2312@2|Bacteria,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CBM_6,DUF1080,DUF1349,Erythro_esteras,GSDH,Glyco_hydro_43,LTD,Laminin_G_3,PKD,SLH
TH3_k127_6235104_11	1045855.DSC_09435	1.746e-25	107.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,1X7HF@135614|Xanthomonadales	135614|Xanthomonadales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
TH3_k127_6235104_14	1303518.CCALI_02493	3.22e-18	94.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_6235104_15	1123242.JH636435_gene1741	9.033e-16	88.0	COG2165@1|root,COG2165@2|Bacteria,2IYZV@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_6235104_22	243233.MCA2974	0.0001974	54.0	COG3291@1|root,COG5563@1|root,COG3291@2|Bacteria,COG5563@2|Bacteria,1QXQ7@1224|Proteobacteria,1T3G4@1236|Gammaproteobacteria,1XGBG@135618|Methylococcales	135618|Methylococcales	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6235104_2	237368.SCABRO_00954	5.296e-191	609.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
TH3_k127_6235104_18	102232.GLO73106DRAFT_00036360	2.546e-08	67.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF5122,FG-GAP,HemolysinCabind
TH3_k127_6235104_17	1182553.XP_007740985.1	1.858e-14	87.0	2EX73@1|root,2SYX9@2759|Eukaryota,3A366@33154|Opisthokonta,3P2YI@4751|Fungi,3QU7S@4890|Ascomycota	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6235104_5	1173026.Glo7428_4012	2.488e-148	486.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria	1117|Cyanobacteria	P	Arylsulfatase a	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
TH3_k127_6235104_0	497964.CfE428DRAFT_2425	0.0	1474.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46U71@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,HEAT_2,Laminin_G_3
TH3_k127_6235104_7	595460.RRSWK_04420	2.242e-119	400.0	COG1070@1|root,COG1070@2|Bacteria,2IXYW@203682|Planctomycetes	203682|Planctomycetes	G	COG1070 Sugar (pentulose and hexulose)	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
TH3_k127_6235104_6	880073.Calab_3508	3.014e-122	402.0	COG1446@1|root,COG1446@2|Bacteria,2NPFC@2323|unclassified Bacteria	2|Bacteria	E	Asparaginase	asnA2	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.1,3.5.1.26	ko:K01424,ko:K01444,ko:K13051	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
TH3_k127_6235104_24	4555.Si032031m	0.0009014	46.0	COG1233@1|root,2QSIC@2759|Eukaryota,37N2T@33090|Viridiplantae,3GBKK@35493|Streptophyta,3KNEA@4447|Liliopsida,3ID4Z@38820|Poales	35493|Streptophyta	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
TH3_k127_6235104_23	9713.XP_006733312.1	0.0001981	55.0	KOG0613@1|root,KOG4475@1|root,KOG0613@2759|Eukaryota,KOG4475@2759|Eukaryota,38BAS@33154|Opisthokonta,3B9IR@33208|Metazoa,3CRJW@33213|Bilateria,484DC@7711|Chordata,48Y8I@7742|Vertebrata,3J1H6@40674|Mammalia,3EFX2@33554|Carnivora	33208|Metazoa	T	Titin Z	TTN	GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	I-set,Ig_2,Ig_3,PPAK,Pkinase,Titin_Z,fn3,ig
TH3_k127_6235104_20	1121287.AUMU01000010_gene1804	6.579e-05	57.0	COG3210@1|root,COG3210@2|Bacteria,4NTNN@976|Bacteroidetes,1IKPF@117743|Flavobacteriia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD
TH3_k127_6235104_19	477641.MODMU_0790	2.278e-07	55.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2I81M@201174|Actinobacteria	201174|Actinobacteria	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
TH3_k127_6235104_8	497964.CfE428DRAFT_1905	1.035e-107	358.0	COG1045@1|root,COG1045@2|Bacteria,46S5J@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
TH3_k127_6255850_1	1396141.BATP01000003_gene4967	3.506e-208	677.0	COG3391@1|root,COG3391@2|Bacteria,46X7X@74201|Verrucomicrobia,2IUXV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
TH3_k127_6255850_3	278963.ATWD01000001_gene2920	5.083e-181	574.0	2CK7V@1|root,2Z9WF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6255850_12	497964.CfE428DRAFT_6276	1.442e-71	268.0	COG2755@1|root,COG2755@2|Bacteria,46SVE@74201|Verrucomicrobia	74201|Verrucomicrobia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TH3_k127_6255850_0	1123508.JH636441_gene3126	1.612e-229	732.0	COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
TH3_k127_6255850_14	1173027.Mic7113_4586	1.944e-40	157.0	COG4636@1|root,COG4636@2|Bacteria,1G2P0@1117|Cyanobacteria,1H6WC@1150|Oscillatoriales	1117|Cyanobacteria	T	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
TH3_k127_6255850_2	452637.Oter_3559	4.762e-183	585.0	COG1070@1|root,COG1070@2|Bacteria,46SI1@74201|Verrucomicrobia,3K7BT@414999|Opitutae	414999|Opitutae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
TH3_k127_6255850_11	1210884.HG799462_gene9284	1.205e-80	277.0	COG0584@1|root,COG0584@2|Bacteria,2IYVE@203682|Planctomycetes	203682|Planctomycetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD_2
TH3_k127_6255850_18	794903.OPIT5_09565	1.575e-07	62.0	COG4969@1|root,COG4969@2|Bacteria,46YC2@74201|Verrucomicrobia,3K9A9@414999|Opitutae	414999|Opitutae	NU	Belongs to the N-Me-Phe pilin family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6255850_6	251221.35213668	9.442e-101	340.0	COG1680@1|root,COG1680@2|Bacteria,1G737@1117|Cyanobacteria	1117|Cyanobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TH3_k127_6255850_16	661478.OP10G_3764	6.638e-14	81.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_6255850_5	497964.CfE428DRAFT_2042	3.136e-155	495.0	COG1087@1|root,COG1087@2|Bacteria,46SIR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
TH3_k127_6255850_13	1121918.ARWE01000001_gene1522	1.224e-47	175.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2WQNR@28221|Deltaproteobacteria,43W09@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	SpoU rRNA Methylase family	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
TH3_k127_6255850_7	1396141.BATP01000027_gene1172	7.497e-98	327.0	COG0101@1|root,COG0101@2|Bacteria,46SSV@74201|Verrucomicrobia,2IU7R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_1
TH3_k127_6255850_15	478741.JAFS01000002_gene271	3.019e-40	154.0	COG0816@1|root,COG0816@2|Bacteria,46T51@74201|Verrucomicrobia,37GTE@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	rnhD	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
TH3_k127_6255850_17	1410613.JNKF01000011_gene1093	7.464e-10	67.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS-HPr
TH3_k127_6255850_4	497964.CfE428DRAFT_1556	1.033e-169	546.0	COG0001@1|root,COG0001@2|Bacteria,46S67@74201|Verrucomicrobia	74201|Verrucomicrobia	H	intramolecular transferase activity, transferring amino groups	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TH3_k127_6255850_10	945713.IALB_0521	2.487e-82	278.0	COG4627@1|root,COG4627@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BON,Glycos_transf_2,Methyltransf_11
TH3_k127_6255850_8	1396418.BATQ01000067_gene1728	6.707e-92	308.0	COG1028@1|root,COG1028@2|Bacteria,46SNA@74201|Verrucomicrobia,2ITSE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TH3_k127_6255850_9	1123070.KB899253_gene1115	1.281e-84	290.0	COG0331@1|root,COG0331@2|Bacteria,46SNS@74201|Verrucomicrobia,2ITTM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
TH3_k127_6255879_0	1173027.Mic7113_2682	8.81e-220	709.0	COG4886@1|root,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1H6Y6@1150|Oscillatoriales	1117|Cyanobacteria	S	COG4886 Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	COR,LRR_4,LRR_8,Roc
TH3_k127_6284625_0	177437.HRM2_39670	0.0	1090.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1MV9F@1224|Proteobacteria,42NS1@68525|delta/epsilon subdivisions,2WQXY@28221|Deltaproteobacteria,2MJAA@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Helicase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
TH3_k127_6284625_2	76114.ebA342	2.652e-32	132.0	COG0537@1|root,COG0537@2|Bacteria,1PE1E@1224|Proteobacteria,2WA47@28216|Betaproteobacteria,2KZD4@206389|Rhodocyclales	206389|Rhodocyclales	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
TH3_k127_6284625_1	765911.Thivi_0827	2.121e-261	825.0	COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1T58S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
TH3_k127_6296937_3	768704.Desmer_2768	3.913e-34	136.0	COG0778@1|root,COG0778@2|Bacteria,1V0NJ@1239|Firmicutes,24FM7@186801|Clostridia,261PI@186807|Peptococcaceae	186801|Clostridia	C	PFAM Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	TM1586_NiRdase
TH3_k127_6296937_4	500632.CLONEX_01925	8.009e-07	63.0	COG1196@1|root,COG3250@1|root,COG4886@1|root,COG1196@2|Bacteria,COG3250@2|Bacteria,COG4886@2|Bacteria,1TPK7@1239|Firmicutes,247VE@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Big_3,Big_4,CBM_6,DUF4982,F5_F8_type_C,FIVAR,Glyco_hydro_2,Glyco_hydro_20b,Glyco_hydro_2_C,Glyco_hydro_2_N,NAGidase
TH3_k127_6296937_2	794903.OPIT5_12355	1.022e-90	332.0	COG1874@1|root,COG1874@2|Bacteria,46Y4Y@74201|Verrucomicrobia,3K8XZ@414999|Opitutae	414999|Opitutae	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
TH3_k127_6296937_1	314230.DSM3645_10617	4.978e-97	345.0	COG3420@1|root,COG3420@2|Bacteria,2J2DV@203682|Planctomycetes	203682|Planctomycetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TH3_k127_6296937_0	497964.CfE428DRAFT_1032	9.073e-113	380.0	COG3170@1|root,COG3170@2|Bacteria,46W02@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6302164_2	1123242.JH636434_gene3154	1.378e-68	252.0	COG2159@1|root,COG2159@2|Bacteria,2J3RZ@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
TH3_k127_6302164_4	1123508.JH636450_gene7204	1.901e-64	238.0	COG0673@1|root,COG0673@2|Bacteria,2IXVF@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_6302164_0	1123242.JH636435_gene772	7.561e-169	541.0	COG0477@1|root,COG2814@2|Bacteria,2J4VW@203682|Planctomycetes	1123242.JH636435_gene772|-	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6302164_3	234267.Acid_7405	7.063e-66	237.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
TH3_k127_6302164_1	1123242.JH636434_gene4323	6.12e-111	375.0	COG1520@1|root,COG4886@1|root,COG1520@2|Bacteria,COG4886@2|Bacteria,2IWWY@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_6302164_5	278957.ABEA03000164_gene4091	2.748e-21	104.0	COG2755@1|root,COG2755@2|Bacteria,46Y7X@74201|Verrucomicrobia,3K931@414999|Opitutae	414999|Opitutae	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TH3_k127_6309601_0	1303518.CCALI_00634	6.635e-129	426.0	28K2K@1|root,2Z9RX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6309601_1	237368.SCABRO_00783	4.899e-52	192.0	28KNW@1|root,2ZA74@2|Bacteria	2|Bacteria	L	Restriction endonuclease XhoI	-	-	3.1.21.4	ko:K01155	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	XhoI
TH3_k127_6309601_3	195250.CM001776_gene223	2.625e-11	72.0	COG1487@1|root,COG1487@2|Bacteria,1G6RD@1117|Cyanobacteria,1H1XR@1129|Synechococcus	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
TH3_k127_6309601_2	909663.KI867150_gene85	4.505e-19	90.0	COG0863@1|root,COG0863@2|Bacteria,1R7RV@1224|Proteobacteria,42NFT@68525|delta/epsilon subdivisions,2WJMQ@28221|Deltaproteobacteria,2MRAU@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
TH3_k127_6331878_16	452637.Oter_0816	1.133e-38	149.0	COG1350@1|root,COG1350@2|Bacteria	2|Bacteria	E	tryptophan synthase activity	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TH3_k127_6331878_11	649638.Trad_1837	6.783e-106	355.0	COG4948@1|root,COG4948@2|Bacteria,1WMNA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Mandelate racemase muconate lactonizing enzyme	ykfB	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
TH3_k127_6331878_5	1123242.JH636434_gene3764	1.846e-141	463.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_6331878_8	1380391.JIAS01000012_gene4526	2.603e-132	434.0	COG4948@1|root,COG4948@2|Bacteria,1R63G@1224|Proteobacteria,2TT3A@28211|Alphaproteobacteria,2JW8D@204441|Rhodospirillales	204441|Rhodospirillales	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
TH3_k127_6331878_17	904296.HMPREF9124_0631	2.486e-34	153.0	28J61@1|root,2Z91S@2|Bacteria,1UYHJ@1239|Firmicutes,24EVG@186801|Clostridia,2PS0Q@265975|Oribacterium	186801|Clostridia	S	Endo-alpha-N-acetylgalactosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_101,Glyco_hydro_129
TH3_k127_6331878_1	997884.HMPREF1068_02702	4.14e-257	843.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia,4AP3C@815|Bacteroidaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,NPCBM
TH3_k127_6331878_18	395961.Cyan7425_3030	1.533e-11	72.0	2E1H4@1|root,33JV3@2|Bacteria,1GGCX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6331878_2	1328313.DS2_07733	7.574e-220	690.0	COG2407@1|root,COG2407@2|Bacteria,1R5ZQ@1224|Proteobacteria,1RNGR@1236|Gammaproteobacteria,469P5@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	L-fucose isomerase, C-terminal domain	-	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Isome,Fucose_iso_C
TH3_k127_6331878_0	1267535.KB906767_gene1403	1.253e-281	899.0	COG3408@1|root,COG3408@2|Bacteria,3Y2YG@57723|Acidobacteria	57723|Acidobacteria	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
TH3_k127_6331878_15	382464.ABSI01000010_gene3476	2.911e-41	164.0	COG0407@1|root,COG5012@1|root,COG0407@2|Bacteria,COG5012@2|Bacteria,46V92@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
TH3_k127_6331878_12	665956.HMPREF1032_00855	4.168e-98	331.0	COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24E75@186801|Clostridia,3WPCX@541000|Ruminococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
TH3_k127_6331878_3	1396141.BATP01000040_gene2191	7.214e-209	659.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,2IVCR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_6331878_4	1499967.BAYZ01000095_gene4068	1.689e-167	535.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
TH3_k127_6331878_9	1123242.JH636434_gene4153	3.357e-113	377.0	COG4409@1|root,COG4409@2|Bacteria,2J53Z@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TH3_k127_6331878_13	1499967.BAYZ01000089_gene5015	3.356e-82	280.0	COG1212@1|root,COG1212@2|Bacteria,2NP8R@2323|unclassified Bacteria	2|Bacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
TH3_k127_6331878_14	265072.Mfla_2506	1.064e-46	188.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2VU7S@28216|Betaproteobacteria,2KMRM@206350|Nitrosomonadales	206350|Nitrosomonadales	FG	PFAM histidine triad (HIT) protein	-	-	-	-	-	-	-	-	-	-	-	-	HIT
TH3_k127_6331878_7	1499967.BAYZ01000089_gene5014	1.293e-137	457.0	COG0043@1|root,COG0043@2|Bacteria	2|Bacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
TH3_k127_6331878_6	1177154.Y5S_00716	3.552e-141	465.0	COG0591@1|root,COG0591@2|Bacteria,1QUXM@1224|Proteobacteria,1T251@1236|Gammaproteobacteria,1XJTT@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TH3_k127_6331878_10	661478.OP10G_0590	3.515e-112	377.0	COG3940@1|root,COG3940@2|Bacteria	2|Bacteria	G	arabinan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N,Glyco_hydro_43,Laminin_G_3
TH3_k127_6336107_4	1170562.Cal6303_0646	8.176e-43	170.0	COG1091@1|root,COG1091@2|Bacteria,1G3IE@1117|Cyanobacteria,1HJTK@1161|Nostocales	1117|Cyanobacteria	M	PFAM RmlD substrate binding domain	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
TH3_k127_6336107_2	639030.JHVA01000001_gene3764	1.016e-81	286.0	COG0399@1|root,COG0399@2|Bacteria,3Y2G1@57723|Acidobacteria,2JP22@204432|Acidobacteriia	204432|Acidobacteriia	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TH3_k127_6336107_3	1294143.H681_11275	2.21e-49	193.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,1RMB3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TH3_k127_6336107_6	1051632.TPY_3664	1.613e-05	53.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	Cupin_2,Cupin_7
TH3_k127_6336107_0	497964.CfE428DRAFT_6606	2.684e-233	732.0	COG1368@1|root,COG1368@2|Bacteria	2|Bacteria	M	sulfuric ester hydrolase activity	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	PMT_2,Sulfatase,Wzy_C
TH3_k127_6336107_1	497964.CfE428DRAFT_5488	6.396e-83	289.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
TH3_k127_6371126_2	1366050.N234_35010	7.071e-15	76.0	29MQ2@1|root,308MT@2|Bacteria,1REUR@1224|Proteobacteria,2VXQA@28216|Betaproteobacteria,1K3YT@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6371126_1	1301098.PKB_2306	9.006e-19	88.0	29MQ2@1|root,308MT@2|Bacteria,1REUR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6371126_0	886293.Sinac_4596	3.832e-187	604.0	2DBS0@1|root,2ZANT@2|Bacteria,2IY4P@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6379528_5	395495.Lcho_0773	1.016e-11	66.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,2VHUB@28216|Betaproteobacteria,1KPAP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
TH3_k127_6379528_4	1056820.KB900700_gene1152	3.048e-22	104.0	COG2968@1|root,COG2968@2|Bacteria,1RC2K@1224|Proteobacteria,1S244@1236|Gammaproteobacteria,2PQ3U@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
TH3_k127_6379528_1	477974.Daud_1182	1.064e-62	227.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,260K3@186807|Peptococcaceae	186801|Clostridia	E	PFAM Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
TH3_k127_6379528_0	2903.EOD40718	1.888e-123	413.0	COG0169@1|root,KOG0692@2759|Eukaryota	2759|Eukaryota	E	shikimate 3-dehydrogenase (NADP+) activity	-	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19,2.7.1.160	ko:K00800,ko:K10669	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	EPSP_synthase
TH3_k127_6379528_2	1123070.KB899248_gene161	1.214e-43	167.0	COG0283@1|root,COG0283@2|Bacteria,46VD5@74201|Verrucomicrobia,2IUAI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Cytidylate kinase	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
TH3_k127_6379528_3	1396418.BATQ01000073_gene500	8.997e-35	138.0	COG0204@1|root,COG0204@2|Bacteria,46SYR@74201|Verrucomicrobia,2IUG8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TH3_k127_6395762_7	251221.35213566	8.287e-68	259.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6395762_16	1408254.T458_02935	3.16e-21	105.0	COG4244@1|root,COG4244@2|Bacteria,1UHFB@1239|Firmicutes,4HCQT@91061|Bacilli,26UEU@186822|Paenibacillaceae	91061|Bacilli	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6395762_4	452637.Oter_3700	1.69e-101	339.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TH3_k127_6395762_12	1115632.JAFW01000001_gene36	4.326e-42	165.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,1W83K@1268|Micrococcaceae	201174|Actinobacteria	J	SpoU rRNA Methylase family	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
TH3_k127_6395762_3	1210884.HG799462_gene8336	3.715e-111	375.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_6395762_14	1192034.CAP_8755	6.203e-33	134.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,42UCT@68525|delta/epsilon subdivisions,2WPAW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
TH3_k127_6395762_6	497964.CfE428DRAFT_6105	3.762e-75	263.0	COG1235@1|root,COG1235@2|Bacteria,46SKU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
TH3_k127_6395762_1	497964.CfE428DRAFT_2602	1.48e-155	507.0	COG1508@1|root,COG1508@2|Bacteria,46SDZ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma-54 factor, RpoN	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
TH3_k127_6395762_11	1210884.HG799464_gene11269	2.315e-42	157.0	COG0681@1|root,COG0681@2|Bacteria,2J14X@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6395762_0	1123508.JH636440_gene2840	1.491e-167	542.0	COG3391@1|root,COG3391@2|Bacteria,2IY6R@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6395762_15	635013.TherJR_2042	9.195e-25	111.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,261SF@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
TH3_k127_6395762_13	497964.CfE428DRAFT_6522	5.808e-38	153.0	COG2045@1|root,COG2045@2|Bacteria	2|Bacteria	H	2-phosphosulfolactate phosphatase activity	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
TH3_k127_6395762_8	497964.CfE428DRAFT_5454	5.1e-64	233.0	COG0122@1|root,COG0122@2|Bacteria,46SVK@74201|Verrucomicrobia	74201|Verrucomicrobia	L	8-oxoguanine DNA glycosylase, N-terminal domain	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
TH3_k127_6395762_9	1396141.BATP01000057_gene2980	6.208e-56	201.0	COG0503@1|root,COG0503@2|Bacteria,46SV8@74201|Verrucomicrobia,2IUHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
TH3_k127_6395762_2	497964.CfE428DRAFT_4839	4.733e-113	374.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TH3_k127_6395762_10	479434.Sthe_1388	1.71e-55	202.0	COG2738@1|root,COG2738@2|Bacteria,2G6KQ@200795|Chloroflexi,27YW2@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
TH3_k127_6395762_5	497964.CfE428DRAFT_2401	1.641e-83	284.0	COG0006@1|root,COG0006@2|Bacteria,46SKG@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
TH3_k127_6436477_0	794903.OPIT5_16815	2.387e-176	557.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia,3K7UQ@414999|Opitutae	414999|Opitutae	C	Aconitase family (aconitate hydratase)	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
TH3_k127_6436477_11	1403819.BATR01000042_gene1260	2.485e-10	67.0	COG3952@1|root,COG3952@2|Bacteria,46T9Z@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N,T2SSG
TH3_k127_6436477_7	234267.Acid_1479	9.299e-54	203.0	COG1609@1|root,COG1609@2|Bacteria,3Y6K5@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
TH3_k127_6436477_8	1123070.KB899253_gene998	1.621e-53	199.0	COG0061@1|root,COG0061@2|Bacteria,46SUQ@74201|Verrucomicrobia,2IUD8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,NAD_kinase
TH3_k127_6436477_4	667014.Thein_0763	1.04e-74	259.0	COG1189@1|root,COG1189@2|Bacteria,2GGSK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
TH3_k127_6436477_10	497964.CfE428DRAFT_5639	1.367e-12	74.0	COG0745@1|root,COG0745@2|Bacteria	497964.CfE428DRAFT_5639|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6436477_1	56780.SYN_00126	1.681e-157	505.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2MR4Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Type IV secretion-system coupling protein DNA-binding domain	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
TH3_k127_6436477_3	1304888.ATWF01000001_gene1852	1.966e-128	420.0	COG2805@1|root,COG2805@2|Bacteria,2GF8B@200930|Deferribacteres	200930|Deferribacteres	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
TH3_k127_6436477_6	1396418.BATQ01000014_gene4333	1.952e-58	217.0	COG1565@1|root,COG1565@2|Bacteria,46T7F@74201|Verrucomicrobia,2IU90@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
TH3_k127_6436477_5	497964.CfE428DRAFT_3657	8.937e-65	230.0	COG1385@1|root,COG1385@2|Bacteria,46SZQ@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
TH3_k127_6436477_2	382464.ABSI01000010_gene3750	1.169e-139	453.0	COG0484@1|root,COG0484@2|Bacteria,46TKC@74201|Verrucomicrobia,2ITUR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
TH3_k127_6436477_9	497964.CfE428DRAFT_3654	4.171e-36	143.0	COG0576@1|root,COG0576@2|Bacteria,46T79@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
TH3_k127_6446357_2	742725.HMPREF9450_00994	5.832e-21	100.0	COG3250@1|root,COG3250@2|Bacteria,4P1Y2@976|Bacteroidetes	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
TH3_k127_6446357_0	742725.HMPREF9450_01035	2.648e-178	590.0	COG3250@1|root,COG3250@2|Bacteria,4P1Y2@976|Bacteroidetes	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
TH3_k127_6446357_3	794903.OPIT5_10530	7.848e-12	70.0	COG2755@1|root,COG2755@2|Bacteria,46UQJ@74201|Verrucomicrobia,3K7D0@414999|Opitutae	414999|Opitutae	E	Sialate O-acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
TH3_k127_6446357_1	595460.RRSWK_04638	4.453e-66	244.0	COG3250@1|root,COG3940@1|root,COG3250@2|Bacteria,COG3940@2|Bacteria	2|Bacteria	G	arabinan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N,Glyco_hydro_43,Laminin_G_3
TH3_k127_6467907_6	1403819.BATR01000017_gene559	2.092e-84	293.0	COG2133@1|root,COG2133@2|Bacteria,46UM9@74201|Verrucomicrobia,2IVKI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_6467907_2	497964.CfE428DRAFT_4760	1.161e-127	413.0	COG1082@1|root,COG1082@2|Bacteria,46SWE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_6467907_11	525904.Tter_0015	4.858e-51	205.0	COG1253@1|root,COG1253@2|Bacteria,2NP9I@2323|unclassified Bacteria	2|Bacteria	S	Transporter associated domain	tlyC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21
TH3_k127_6467907_14	497964.CfE428DRAFT_0673	5.115e-23	112.0	COG1253@1|root,COG1253@2|Bacteria,46W8Q@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	DUF21
TH3_k127_6467907_5	696281.Desru_1739	2.908e-104	353.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,26052@186807|Peptococcaceae	186801|Clostridia	S	CBS domain-containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
TH3_k127_6467907_17	28444.JODQ01000003_gene4977	4.053e-07	61.0	COG2324@1|root,COG2324@2|Bacteria,2IIUJ@201174|Actinobacteria,4EIUK@85012|Streptosporangiales	201174|Actinobacteria	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
TH3_k127_6467907_13	583355.Caka_0236	1.457e-25	111.0	2A5NK@1|root,30UDC@2|Bacteria,46YMP@74201|Verrucomicrobia,3K9UM@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6467907_4	452637.Oter_0016	3.658e-108	369.0	COG0530@1|root,COG0530@2|Bacteria,46Y13@74201|Verrucomicrobia,3K8RV@414999|Opitutae	414999|Opitutae	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
TH3_k127_6467907_10	452637.Oter_2422	1.725e-56	204.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
TH3_k127_6467907_12	452637.Oter_4175	2.11e-26	112.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TH3_k127_6467907_1	452637.Oter_1389	2.041e-136	458.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TH3_k127_6467907_3	498848.TaqDRAFT_4878	7.375e-116	398.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6467907_15	635013.TherJR_1860	1.832e-15	81.0	COG1872@1|root,COG1872@2|Bacteria,1VFSH@1239|Firmicutes,24T87@186801|Clostridia,262RJ@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
TH3_k127_6467907_8	497964.CfE428DRAFT_3900	4.251e-58	211.0	2AU2S@1|root,31JP5@2|Bacteria,46VDJ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_6467907_7	530564.Psta_1556	3.839e-60	220.0	29525@1|root,2ZSEY@2|Bacteria,2IZ8U@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6467907_9	323261.Noc_1412	5.132e-58	208.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,1X0Q2@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
TH3_k127_6467907_0	497964.CfE428DRAFT_1603	4.104e-179	573.0	COG0673@1|root,COG0673@2|Bacteria,46TYR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_6467907_16	1396141.BATP01000016_gene2783	1.203e-11	76.0	2BN1X@1|root,32GN2@2|Bacteria,46XN3@74201|Verrucomicrobia,2IW8A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6472963_0	530564.Psta_3017	4.307e-255	801.0	COG1053@1|root,COG1053@2|Bacteria,2IXHQ@203682|Planctomycetes	203682|Planctomycetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
TH3_k127_6472963_3	926549.KI421517_gene3311	2.546e-40	174.0	COG1520@1|root,COG3210@1|root,COG3405@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3405@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
TH3_k127_6472963_4	1291050.JAGE01000002_gene3876	1.099e-26	129.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,3WIWU@541000|Ruminococcaceae	186801|Clostridia	O	Subtilase family	-	-	-	ko:K13276,ko:K17734	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarboxypepD_reg,Cu_amine_oxidN1,Inhibitor_I9,LRR_5,PPC,Peptidase_S8
TH3_k127_6472963_6	103733.JNYO01000007_gene5239	6.016e-05	57.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4E1H7@85010|Pseudonocardiales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TH3_k127_6472963_1	497964.CfE428DRAFT_2672	4.492e-232	730.0	COG0043@1|root,COG0043@2|Bacteria,46TYE@74201|Verrucomicrobia	74201|Verrucomicrobia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
TH3_k127_6472963_2	240016.ABIZ01000001_gene3765	3.949e-51	188.0	COG1943@1|root,COG1943@2|Bacteria,46VYR@74201|Verrucomicrobia,2IW8N@203494|Verrucomicrobiae	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
TH3_k127_6472963_5	497964.CfE428DRAFT_2672	2.165e-11	66.0	COG0043@1|root,COG0043@2|Bacteria,46TYE@74201|Verrucomicrobia	74201|Verrucomicrobia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
TH3_k127_6479052_18	1122931.AUAE01000028_gene113	1.468e-41	160.0	2CB8C@1|root,33T5I@2|Bacteria,4P0N1@976|Bacteroidetes,2FX4B@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6479052_2	452637.Oter_2972	2.349e-215	679.0	COG3669@1|root,COG3669@2|Bacteria,46Y1K@74201|Verrucomicrobia,3K8SP@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase family 29	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
TH3_k127_6479052_23	1210884.HG799480_gene15519	4.175e-26	116.0	COG1387@1|root,COG1387@2|Bacteria,2IZ7D@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_6479052_16	1303518.CCALI_02246	7.374e-55	215.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,CHB_HEX_C_1,Cellulase,F5_F8_type_C
TH3_k127_6479052_15	1396141.BATP01000002_gene4845	2.762e-58	213.0	COG2197@1|root,COG2197@2|Bacteria,46TQM@74201|Verrucomicrobia,2IVME@203494|Verrucomicrobiae	2|Bacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_6479052_11	1396141.BATP01000002_gene4846	8.567e-84	302.0	COG4585@1|root,COG4585@2|Bacteria,46UGH@74201|Verrucomicrobia,2IVFF@203494|Verrucomicrobiae	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_3
TH3_k127_6479052_26	864051.BurJ1DRAFT_3700	3.098e-17	96.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
TH3_k127_6479052_27	278957.ABEA03000106_gene1817	1.407e-16	89.0	COG4968@1|root,COG4968@2|Bacteria,46Y7B@74201|Verrucomicrobia,3K91Z@414999|Opitutae	414999|Opitutae	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6479052_24	391603.FBALC1_06473	4.098e-24	120.0	COG2133@1|root,COG3291@1|root,COG3511@1|root,COG5563@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3511@2|Bacteria,COG5563@2|Bacteria	2|Bacteria	M	phospholipase C	psrP1	-	1.1.3.9	ko:K04618	ko00052,map00052	-	R01098	RC00194	ko00000,ko00001,ko01000	-	-	-	CHU_C,DUF1929,F5_F8_type_C,GSDH,fn3
TH3_k127_6479052_3	1122931.AUAE01000013_gene2105	1.624e-194	647.0	COG3250@1|root,COG3250@2|Bacteria,4NEP8@976|Bacteroidetes,2FWKT@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TH3_k127_6479052_7	1396141.BATP01000003_gene5168	2.543e-136	451.0	2EKQJ@1|root,33EEC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6479052_0	1132441.KI519454_gene1142	1.249e-269	854.0	COG1554@1|root,COG1554@2|Bacteria,2GJXJ@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6479052_9	273068.TTE2349	9.231e-93	322.0	COG5520@1|root,COG5520@2|Bacteria,1TS99@1239|Firmicutes,249YD@186801|Clostridia,42HSQ@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
TH3_k127_6479052_10	234267.Acid_7682	2.21e-89	309.0	COG2133@1|root,COG2133@2|Bacteria,3Y6W0@57723|Acidobacteria	57723|Acidobacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
TH3_k127_6479052_20	28444.JODQ01000006_gene629	1.099e-35	143.0	COG3963@1|root,COG3963@2|Bacteria,2I93P@201174|Actinobacteria,4EJ7V@85012|Streptosporangiales	201174|Actinobacteria	I	Phospholipid N-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,RrnaAD
TH3_k127_6479052_4	497964.CfE428DRAFT_3485	8.58e-176	559.0	COG0673@1|root,COG0673@2|Bacteria,46SBW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_6479052_19	459349.CLOAM0160	1.758e-41	166.0	COG0671@1|root,COG0671@2|Bacteria,2NRVZ@2323|unclassified Bacteria	2|Bacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
TH3_k127_6479052_30	755178.Cyan10605_0953	1.723e-10	73.0	COG3307@1|root,COG3307@2|Bacteria,1G1ZH@1117|Cyanobacteria	1117|Cyanobacteria	M	bicarbonate transporter, IctB family	ictB	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
TH3_k127_6479052_22	338966.Ppro_1664	4.037e-32	138.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,43BTG@68525|delta/epsilon subdivisions,2X74B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III, delta'	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
TH3_k127_6479052_17	489825.LYNGBM3L_17040	2.262e-48	186.0	COG1266@1|root,COG1266@2|Bacteria,1G5HB@1117|Cyanobacteria,1HAXC@1150|Oscillatoriales	1117|Cyanobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
TH3_k127_6479052_5	1403819.BATR01000002_gene28	1.199e-156	505.0	COG1253@1|root,COG1253@2|Bacteria,46U7J@74201|Verrucomicrobia,2IVE3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
TH3_k127_6479052_12	756272.Plabr_1391	3.359e-79	275.0	COG1082@1|root,COG1082@2|Bacteria,2IXXX@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
TH3_k127_6479052_1	452637.Oter_0071	2.705e-221	715.0	COG3127@1|root,COG3127@2|Bacteria,46UKQ@74201|Verrucomicrobia,3K7U2@414999|Opitutae	414999|Opitutae	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TH3_k127_6479052_8	1121957.ATVL01000008_gene3992	5.79e-94	315.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,47JSN@768503|Cytophagia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_6479052_14	517418.Ctha_1767	2.322e-67	237.0	COG2755@1|root,COG2755@2|Bacteria,1FET3@1090|Chlorobi	1090|Chlorobi	E	GDSL-like Lipase/Acylhydrolase family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
TH3_k127_6479052_13	344747.PM8797T_07504	6.24e-71	250.0	COG0428@1|root,COG0428@2|Bacteria,2IZ3C@203682|Planctomycetes	203682|Planctomycetes	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
TH3_k127_6479052_28	1303518.CCALI_02381	2.278e-14	82.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_6479052_6	1449126.JQKL01000015_gene2921	3.582e-138	451.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,26865@186813|unclassified Clostridiales	186801|Clostridia	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
TH3_k127_6479052_21	502025.Hoch_6396	2.765e-33	144.0	2DBMC@1|root,2Z9YC@2|Bacteria,1PY40@1224|Proteobacteria,43E0Z@68525|delta/epsilon subdivisions,2WZDV@28221|Deltaproteobacteria,2Z1X8@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6479052_25	1396418.BATQ01000085_gene1078	2.139e-18	87.0	COG0304@1|root,COG0304@2|Bacteria	2|Bacteria	I	3-oxoacyl-[acyl-carrier-protein] synthase activity	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
TH3_k127_6487344_6	547042.BACCOPRO_00511	7.703e-51	204.0	COG2819@1|root,COG2819@2|Bacteria,4NGJB@976|Bacteroidetes,2FR8R@200643|Bacteroidia,4AQA2@815|Bacteroidaceae	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
TH3_k127_6487344_2	344747.PM8797T_32395	2.699e-113	387.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41,Tricorn_C1
TH3_k127_6487344_9	886293.Sinac_4894	1.038e-32	132.0	COG1595@1|root,COG1595@2|Bacteria,2J3UT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_6487344_8	886293.Sinac_4894	3.187e-33	142.0	COG1595@1|root,COG1595@2|Bacteria,2J3UT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_6487344_10	886293.Sinac_4894	1.987e-20	108.0	COG1595@1|root,COG1595@2|Bacteria,2J3UT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_6487344_3	497964.CfE428DRAFT_2981	3.467e-104	371.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1648,DUF4019,Pkinase
TH3_k127_6487344_5	794903.OPIT5_27940	2.231e-59	218.0	COG1595@1|root,COG1595@2|Bacteria,46YS4@74201|Verrucomicrobia,3K8W5@414999|Opitutae	414999|Opitutae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
TH3_k127_6487344_0	314230.DSM3645_10902	6.632e-278	878.0	COG0823@1|root,COG1506@1|root,COG4805@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,COG4805@2|Bacteria,2IY8M@203682|Planctomycetes	203682|Planctomycetes	E	Dipeptidyl peptidase IV (DPP IV)	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,DUF885,Peptidase_S9,VHL
TH3_k127_6487344_4	383372.Rcas_3244	2.083e-70	271.0	COG3250@1|root,COG3250@2|Bacteria,2G6ZW@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glyco_hydro_2_N
TH3_k127_6487344_11	1121904.ARBP01000002_gene7118	2.604e-11	78.0	COG3250@1|root,COG3250@2|Bacteria,4NN59@976|Bacteroidetes	976|Bacteroidetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BetaGal_dom4_5
TH3_k127_6487344_13	46234.ANA_C10684	5.947e-06	51.0	COG2026@1|root,COG2026@2|Bacteria,1GA93@1117|Cyanobacteria,1HT80@1161|Nostocales	1117|Cyanobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
TH3_k127_6487344_12	42565.FP66_10530	4.905e-07	61.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	SPOR,Sel1
TH3_k127_6487344_1	1313421.JHBV01000041_gene3629	5.337e-186	609.0	COG2304@1|root,COG2304@2|Bacteria,4NK2W@976|Bacteroidetes	976|Bacteroidetes	M	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	OmpA,VIT,VWA,VWA_3
TH3_k127_6487344_7	1304885.AUEY01000096_gene2839	4.447e-36	140.0	COG1404@1|root,COG2304@1|root,COG2911@1|root,COG3897@1|root,COG5434@1|root,COG1404@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,COG3897@2|Bacteria,COG5434@2|Bacteria,1P8N9@1224|Proteobacteria,43DXZ@68525|delta/epsilon subdivisions,2X72D@28221|Deltaproteobacteria,2MNHJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
TH3_k127_6487700_1	1178825.ALIH01000004_gene2807	9.489e-131	430.0	COG3408@1|root,COG5520@1|root,COG3408@2|Bacteria,COG5520@2|Bacteria,4NM34@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl hydrolase family 59	-	-	3.2.1.46	ko:K01202	ko00600,ko01100,ko04142,map00600,map01100,map04142	-	R03617	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH59	-	Glyco_hydro_59
TH3_k127_6487700_0	1235803.C825_01953	2.974e-273	882.0	COG0639@1|root,COG0639@2|Bacteria,4NZWK@976|Bacteroidetes,2FPXD@200643|Bacteroidia	976|Bacteroidetes	T	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
TH3_k127_6487700_6	1211813.CAPH01000009_gene63	0.0009163	43.0	COG4692@1|root,COG4692@2|Bacteria,4PKSV@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-L-rhamnosidase N-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	BNR_2,Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
TH3_k127_6487700_4	1396141.BATP01000004_gene5925	1.544e-27	122.0	COG3250@1|root,COG4692@1|root,COG3250@2|Bacteria,COG4692@2|Bacteria,46Z9T@74201|Verrucomicrobia,2IWDF@203494|Verrucomicrobiae	2|Bacteria	G	Alpha-L-rhamnosidase N-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,NPCBM_assoc
TH3_k127_6487700_5	335543.Sfum_3211	9.499e-23	111.0	COG3437@1|root,COG4585@1|root,COG3437@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42RUN@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS,PAS_9
TH3_k127_6487700_3	255470.cbdbA1042	7.358e-45	169.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8KS@200795|Chloroflexi,34CTW@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS_3,PAS_9
TH3_k127_6487700_2	452637.Oter_1700	2.738e-66	232.0	COG2197@1|root,COG2197@2|Bacteria,46UGC@74201|Verrucomicrobia,3K7ZK@414999|Opitutae	74201|Verrucomicrobia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_6489860_3	35128.Thaps23576	2.705e-05	49.0	2ENJE@1|root,2SRZD@2759|Eukaryota,2XGJZ@2836|Bacillariophyta	2836|Bacillariophyta	S	Helicase associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HA
TH3_k127_6489860_0	395494.Galf_2787	1.63e-254	810.0	COG1111@1|root,COG4889@1|root,COG1111@2|Bacteria,COG4889@2|Bacteria,1P17M@1224|Proteobacteria,2WHHU@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat_2
TH3_k127_6489860_1	420324.KI911932_gene324	6.451e-19	90.0	2EHAG@1|root,3394C@2|Bacteria,1NK4E@1224|Proteobacteria,2UJZB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Family of unknown function (DUF5372)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5372
TH3_k127_6489860_2	1366050.N234_27952	7.404e-16	82.0	COG3415@1|root,COG3415@2|Bacteria,1RKUV@1224|Proteobacteria,2WFVI@28216|Betaproteobacteria,1KI6K@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29
TH3_k127_6489925_3	237368.SCABRO_00954	4.256e-11	66.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
TH3_k127_6489925_0	452637.Oter_2229	3.928e-273	870.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Glyco_hydro_16,Glyco_transf_25,Malectin,Ricin_B_lectin,Trans_reg_C,Trypsin,VCBS
TH3_k127_6489925_2	700598.Niako_5388	1.583e-52	199.0	COG3669@1|root,COG3669@2|Bacteria,4NWP5@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
TH3_k127_6489925_1	530564.Psta_0688	5.082e-161	519.0	28MMN@1|root,2ZAXE@2|Bacteria,2IY1P@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6490216_4	1123242.JH636434_gene4965	2.763e-150	492.0	COG0477@1|root,COG2814@2|Bacteria,2IYPH@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TH3_k127_6490216_1	794903.OPIT5_20520	8.755e-169	545.0	COG0147@1|root,COG0147@2|Bacteria,46S4I@74201|Verrucomicrobia,3K72I@414999|Opitutae	414999|Opitutae	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
TH3_k127_6490216_24	42256.RradSPS_3110	7.071e-15	76.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6490216_30	118166.JH976537_gene1582	1.793e-08	58.0	COG3210@1|root,COG3210@2|Bacteria,1G775@1117|Cyanobacteria,1HCW7@1150|Oscillatoriales	1117|Cyanobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6490216_26	1183438.GKIL_3127	2.434e-13	72.0	2E6Q0@1|root,331A9@2|Bacteria,1G9WU@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4926)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4926
TH3_k127_6490216_28	266809.PM03_10895	1.471e-11	65.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
TH3_k127_6490216_13	111781.Lepto7376_0105	1.908e-72	262.0	COG1520@1|root,COG3210@1|root,COG3595@1|root,COG4995@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3595@2|Bacteria,COG4995@2|Bacteria,1G08N@1117|Cyanobacteria,1H96Q@1150|Oscillatoriales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act,P_proprotein
TH3_k127_6490216_27	794903.OPIT5_29985	1.128e-12	71.0	COG1533@1|root,COG1533@2|Bacteria	2|Bacteria	L	DNA photolyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TH3_k127_6490216_14	794903.OPIT5_29985	5.625e-71	252.0	COG1533@1|root,COG1533@2|Bacteria	2|Bacteria	L	DNA photolyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TH3_k127_6490216_25	338969.Rfer_1071	1.951e-14	83.0	COG1028@1|root,COG1028@2|Bacteria,1RBAD@1224|Proteobacteria,2VI9U@28216|Betaproteobacteria,4AA6I@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase Sdr	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6490216_23	525904.Tter_1255	3.157e-17	85.0	COG0147@1|root,COG0147@2|Bacteria,2NNRD@2323|unclassified Bacteria	2|Bacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
TH3_k127_6490216_5	1125973.JNLC01000011_gene481	9.067e-144	469.0	COG0665@1|root,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,3JXXJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
TH3_k127_6490216_10	1123242.JH636434_gene5139	2.103e-93	318.0	COG2025@1|root,COG2025@2|Bacteria,2J3Y1@203682|Planctomycetes	203682|Planctomycetes	C	Electron transfer flavoprotein domain	-	-	-	-	-	-	-	-	-	-	-	-	ETF,ETF_alpha
TH3_k127_6490216_12	1121106.JQKB01000007_gene972	7.933e-77	266.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2TR4J@28211|Alphaproteobacteria,2JPSB@204441|Rhodospirillales	204441|Rhodospirillales	C	Electron transfer flavoprotein, beta subunit	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
TH3_k127_6490216_17	1380394.JADL01000001_gene2442	5.993e-58	217.0	COG0665@1|root,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,2JREU@204441|Rhodospirillales	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
TH3_k127_6490216_2	635013.TherJR_0057	1.174e-157	512.0	COG5598@1|root,COG5598@2|Bacteria,1V08E@1239|Firmicutes,24BDE@186801|Clostridia,263XC@186807|Peptococcaceae	186801|Clostridia	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
TH3_k127_6490216_7	1116369.KB890025_gene5283	1.684e-112	377.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,43GYK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Rieske 2Fe-2S	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
TH3_k127_6490216_9	1240350.AMZE01000024_gene1610	1.308e-98	338.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,1RMB3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	transporter	-	-	-	ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
TH3_k127_6490216_22	1123256.KB907940_gene188	2.547e-22	103.0	COG2839@1|root,COG2839@2|Bacteria,1MZEV@1224|Proteobacteria,1SAFY@1236|Gammaproteobacteria,1X6YB@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
TH3_k127_6490216_0	478741.JAFS01000002_gene849	4.247e-173	553.0	COG0334@1|root,COG0334@2|Bacteria,46S9K@74201|Verrucomicrobia,37G3K@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
TH3_k127_6490216_15	1254432.SCE1572_15425	1.727e-64	229.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,42RT9@68525|delta/epsilon subdivisions,2WNJ0@28221|Deltaproteobacteria,2YWKZ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_1658	Fer4_14,Radical_SAM
TH3_k127_6490216_6	1123070.KB899254_gene1284	2.44e-118	396.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
TH3_k127_6490216_18	665952.HMPREF1015_02804	1.592e-47	183.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,1ZBZX@1386|Bacillus	91061|Bacilli	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
TH3_k127_6490216_16	452637.Oter_2376	2.302e-59	209.0	COG1443@1|root,COG1443@2|Bacteria,46T1S@74201|Verrucomicrobia,3K84X@414999|Opitutae	414999|Opitutae	I	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TH3_k127_6490216_19	246197.MXAN_1687	1.278e-31	137.0	2A102@1|root,30P5F@2|Bacteria,1NQ9E@1224|Proteobacteria	1224|Proteobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
TH3_k127_6490216_11	1156937.MFUM_170024	1.714e-87	295.0	COG0740@1|root,COG0740@2|Bacteria,46SAB@74201|Verrucomicrobia,37G7G@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
TH3_k127_6490216_3	511062.GU3_08515	4.755e-156	503.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1Y3ZI@135624|Aeromonadales	135624|Aeromonadales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
TH3_k127_6490216_29	452637.Oter_1161	1.887e-09	62.0	COG4575@1|root,COG4575@2|Bacteria,46WFC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
TH3_k127_6490216_8	1123393.KB891317_gene2207	3.745e-104	346.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2VQ9J@28216|Betaproteobacteria,1KSDQ@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
TH3_k127_6490216_31	314345.SPV1_00987	1.062e-07	60.0	2DPGY@1|root,3320R@2|Bacteria,1ND7F@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
TH3_k127_6490216_21	1173027.Mic7113_2682	1.173e-24	111.0	COG4886@1|root,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1H6Y6@1150|Oscillatoriales	1117|Cyanobacteria	S	COG4886 Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	COR,LRR_4,LRR_8,Roc
TH3_k127_6528500_9	1210884.HG799469_gene14127	4.843e-46	173.0	COG0385@1|root,COG0385@2|Bacteria	2|Bacteria	S	bile acid:sodium symporter activity	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
TH3_k127_6528500_5	56780.SYN_02948	1.504e-72	265.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42Q4P@68525|delta/epsilon subdivisions,2WJHQ@28221|Deltaproteobacteria,2MR8F@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TH3_k127_6528500_0	1121438.JNJA01000018_gene3312	0.0	1026.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2M817@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
TH3_k127_6528500_3	204669.Acid345_4072	5.307e-122	412.0	COG1538@1|root,COG1538@2|Bacteria,3Y2NR@57723|Acidobacteria,2JHZY@204432|Acidobacteriia	204432|Acidobacteriia	MU	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
TH3_k127_6528500_2	1403819.BATR01000067_gene2010	4.824e-148	472.0	COG2326@1|root,COG2326@2|Bacteria,46UWN@74201|Verrucomicrobia,2IVFJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
TH3_k127_6528500_8	1121403.AUCV01000010_gene1383	1.824e-46	177.0	COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,42NVT@68525|delta/epsilon subdivisions,2WIRY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	ET	PFAM Extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
TH3_k127_6528500_6	870187.Thini_1169	7.806e-72	252.0	COG0589@1|root,COG0589@2|Bacteria,1N5Z8@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TH3_k127_6528500_12	1336233.JAEH01000025_gene1035	4.658e-08	63.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,2Q9HF@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
TH3_k127_6528500_7	1088869.GMO_02930	4.049e-50	190.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria	1224|Proteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
TH3_k127_6528500_11	247490.KSU1_C1448	6.357e-31	130.0	2CA7I@1|root,30E5G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6528500_10	909663.KI867150_gene2890	9.468e-43	173.0	COG3064@1|root,COG3064@2|Bacteria,1MXPS@1224|Proteobacteria,42PA3@68525|delta/epsilon subdivisions,2WM6X@28221|Deltaproteobacteria,2MQSC@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Protein of unknown function (DUF3300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3300
TH3_k127_6528500_4	909663.KI867150_gene2891	1.704e-80	280.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,42MTK@68525|delta/epsilon subdivisions,2WM8U@28221|Deltaproteobacteria,2MQWV@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
TH3_k127_6528500_1	1396141.BATP01000001_gene5389	5.157e-231	727.0	COG0659@1|root,COG0659@2|Bacteria,46TUB@74201|Verrucomicrobia,2IVJF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
TH3_k127_6538662_0	323259.Mhun_0476	1.067e-63	228.0	COG0500@1|root,arCOG01791@2157|Archaea,2XZTQ@28890|Euryarchaeota	28890|Euryarchaeota	Q	Methyltransferase type 11	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25
TH3_k127_6538662_1	56780.SYN_03067	1.381e-36	149.0	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SmpA_OmlA,SusD-like_3
TH3_k127_6538662_2	5145.XP_001903535.1	4.819e-28	128.0	KOG0272@1|root,KOG0272@2759|Eukaryota,3AFR9@33154|Opisthokonta,3Q43U@4751|Fungi,3RM91@4890|Ascomycota,21RI5@147550|Sordariomycetes	4751|Fungi	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	HET,NACHT,NACHT_N,WD40
TH3_k127_6573031_0	1254432.SCE1572_14255	1.257e-203	646.0	COG2978@1|root,COG2978@2|Bacteria,1MUJ1@1224|Proteobacteria,42N8Z@68525|delta/epsilon subdivisions,2WTR2@28221|Deltaproteobacteria,2YU56@29|Myxococcales	28221|Deltaproteobacteria	H	AbgT putative transporter family	abgT	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
TH3_k127_6573031_4	234267.Acid_3218	3.666e-51	184.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
TH3_k127_6573031_1	452637.Oter_1503	7.137e-139	455.0	COG2081@1|root,COG2081@2|Bacteria,46TWE@74201|Verrucomicrobia,3K7FU@414999|Opitutae	414999|Opitutae	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
TH3_k127_6573031_2	452637.Oter_1311	1.948e-76	264.0	COG2454@1|root,COG2454@2|Bacteria,46W2F@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6573031_6	886293.Sinac_3510	6.84e-43	171.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF11,PKD
TH3_k127_6573031_3	1379698.RBG1_1C00001G0608	6.188e-70	254.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
TH3_k127_6573031_7	35754.JNYJ01000007_gene2850	3.236e-05	53.0	COG3537@1|root,COG3537@2|Bacteria,2GKYM@201174|Actinobacteria,4DAT5@85008|Micromonosporales	201174|Actinobacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_92
TH3_k127_6582277_0	497964.CfE428DRAFT_1607	2.061e-201	638.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
TH3_k127_6582277_2	1267534.KB906758_gene2376	7.113e-198	626.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_6582277_1	1123276.KB893270_gene4720	2.937e-200	635.0	COG0673@1|root,COG0673@2|Bacteria,4NHDZ@976|Bacteroidetes,47KJR@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_6582277_3	497964.CfE428DRAFT_0793	1.306e-75	256.0	COG0450@1|root,COG0450@2|Bacteria,46STI@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
TH3_k127_6586086_6	1051632.TPY_0876	0.0003345	53.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,24GKC@186801|Clostridia	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
TH3_k127_6586086_2	497964.CfE428DRAFT_3031	2.15e-56	208.0	COG1624@1|root,COG1624@2|Bacteria,46SSQ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
TH3_k127_6586086_1	404589.Anae109_2337	4.515e-81	280.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,2YVIZ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
TH3_k127_6586086_3	240016.ABIZ01000001_gene1545	2.366e-45	170.0	COG0346@1|root,COG0346@2|Bacteria,46SUF@74201|Verrucomicrobia,2IUKG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TH3_k127_6586086_4	278957.ABEA03000062_gene3554	4.681e-13	79.0	COG2165@1|root,COG2165@2|Bacteria,46YIN@74201|Verrucomicrobia,3K9NX@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
TH3_k127_6586086_5	1210884.HG799465_gene12051	1.208e-08	66.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_6586086_0	452637.Oter_1547	0.0	1313.0	COG3808@1|root,COG3808@2|Bacteria,46S7R@74201|Verrucomicrobia,3K82Q@414999|Opitutae	414999|Opitutae	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
TH3_k127_6592672_8	497964.CfE428DRAFT_1215	2.805e-52	188.0	COG1100@1|root,COG1100@2|Bacteria,46VDZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Ras family	-	-	-	-	-	-	-	-	-	-	-	-	Arf
TH3_k127_6592672_3	497964.CfE428DRAFT_1213	7.016e-105	351.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	DUF4388,HATPase_c,HTH_8,HisKA,Response_reg,SSF,Sigma54_activat
TH3_k127_6592672_5	497964.CfE428DRAFT_6252	2.297e-82	285.0	COG1968@1|root,COG1968@2|Bacteria,46SP6@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
TH3_k127_6592672_2	471853.Bcav_3390	6.464e-132	443.0	COG2730@1|root,COG3537@1|root,COG4225@1|root,COG2730@2|Bacteria,COG3537@2|Bacteria,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,F5_F8_type_C,Hepar_II_III,Ricin_B_lectin
TH3_k127_6592672_15	203119.Cthe_3006	0.0001447	52.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,1V9XU@1239|Firmicutes,24NW6@186801|Clostridia	186801|Clostridia	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
TH3_k127_6592672_7	945713.IALB_3143	1.898e-60	214.0	COG0229@1|root,COG0229@2|Bacteria	2|Bacteria	O	peptide-methionine (R)-S-oxide reductase activity	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
TH3_k127_6592672_13	756272.Plabr_3911	3.415e-21	106.0	COG4632@1|root,COG4632@2|Bacteria,2J149@203682|Planctomycetes	203682|Planctomycetes	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
TH3_k127_6592672_11	671143.DAMO_0425	1.378e-28	117.0	COG3646@1|root,COG3646@2|Bacteria	2|Bacteria	L	Phage regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
TH3_k127_6592672_12	936574.HMPREF1508_0899	1.276e-21	97.0	COG1502@1|root,COG1502@2|Bacteria,1TRJE@1239|Firmicutes,248ZE@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
TH3_k127_6592672_0	1396418.BATQ01000166_gene1868	1.66e-215	675.0	COG0137@1|root,COG0137@2|Bacteria,46SCU@74201|Verrucomicrobia,2ITYG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
TH3_k127_6592672_4	1379698.RBG1_1C00001G0123	3.721e-90	306.0	COG0053@1|root,COG0053@2|Bacteria,2NPHA@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
TH3_k127_6592672_1	880073.Calab_3201	5.68e-142	461.0	COG4198@1|root,COG4198@2|Bacteria,2NNV0@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF1015)	gdh	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	DUF1015
TH3_k127_6592672_6	765420.OSCT_3130	2.482e-71	252.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
TH3_k127_6592672_14	452637.Oter_3785	1.694e-19	90.0	COG0227@1|root,COG0227@2|Bacteria,46TBF@74201|Verrucomicrobia,3K89C@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
TH3_k127_6606606_2	1123508.JH636456_gene146	2.306e-236	736.0	COG2217@1|root,COG2217@2|Bacteria,2IXAD@203682|Planctomycetes	203682|Planctomycetes	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
TH3_k127_6606606_8	1167006.UWK_00988	9.774e-55	198.0	2BK9M@1|root,32EPT@2|Bacteria,1NC6I@1224|Proteobacteria,42XFJ@68525|delta/epsilon subdivisions,2WT5J@28221|Deltaproteobacteria,2MP6B@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6606606_6	330214.NIDE3676	2.488e-64	239.0	2DBP7@1|root,2ZA82@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6606606_7	330214.NIDE3675	9.761e-64	227.0	2DKWD@1|root,30KRK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
TH3_k127_6606606_9	638302.HMPREF0908_1797	1.2e-26	116.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4H4K0@909932|Negativicutes	909932|Negativicutes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
TH3_k127_6606606_5	1396418.BATQ01000125_gene5090	1.077e-107	357.0	COG0484@1|root,COG0484@2|Bacteria,46S6P@74201|Verrucomicrobia,2IV3Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,DnaJ_C
TH3_k127_6606606_10	794903.OPIT5_26490	2.625e-11	72.0	2C4M3@1|root,2ZD1R@2|Bacteria,46WTA@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_2
TH3_k127_6606606_1	697282.Mettu_0620	0.0	1387.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1XEHU@135618|Methylococcales	135618|Methylococcales	G	TIGRFAM alpha-glucan	-	-	-	-	-	-	-	-	-	-	-	-	DUF3417,Phosphorylase
TH3_k127_6606606_0	261292.Nit79A3_0034	0.0	1424.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,3743H@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Cation transporter/ATPase, N-terminus	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
TH3_k127_6606606_3	1232410.KI421421_gene3328	8.637e-213	672.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,43S64@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
TH3_k127_6606606_4	1403819.BATR01000093_gene2905	9.534e-148	476.0	COG3239@1|root,COG3239@2|Bacteria,46SX7@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Fatty acid desaturase	desA	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TH3_k127_6643084_4	886293.Sinac_2826	1.943e-08	67.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
TH3_k127_6643084_2	1210884.HG799464_gene11092	2.055e-15	89.0	COG1668@1|root,COG1668@2|Bacteria,2IXFE@203682|Planctomycetes	203682|Planctomycetes	CP	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
TH3_k127_6643084_5	1321782.HMPREF1986_02031	1.142e-06	61.0	COG1277@1|root,COG1277@2|Bacteria,1VFPF@1239|Firmicutes,25FX9@186801|Clostridia,2PRI4@265975|Oribacterium	186801|Clostridia	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC2_membrane_2
TH3_k127_6643084_3	679200.HMPREF9333_00914	2.367e-10	74.0	COG1277@1|root,COG1277@2|Bacteria,1V90F@1239|Firmicutes,25DFP@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
TH3_k127_6643084_1	1210884.HG799473_gene15021	1.089e-183	586.0	2BXG3@1|root,2Z82R@2|Bacteria,2IXSD@203682|Planctomycetes	203682|Planctomycetes	S	tagaturonate epimerase	-	-	5.1.2.7	ko:K21619	ko00040,ko01100,map00040,map01100	-	R11624	-	ko00000,ko00001,ko01000	-	-	-	UxaE
TH3_k127_6643084_0	234267.Acid_7084	1.308e-207	648.0	COG0524@1|root,COG0524@2|Bacteria,3Y3DE@57723|Acidobacteria	57723|Acidobacteria	G	PfkB domain protein	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
TH3_k127_6643084_6	395495.Lcho_4142	1.445e-06	51.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria,1KK1H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
TH3_k127_6650041_1	118166.JH976538_gene5043	4.213e-212	675.0	28H5N@1|root,2Z7I8@2|Bacteria,1GCEG@1117|Cyanobacteria,1HE1R@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6650041_0	118166.JH976538_gene5042	7.185e-316	996.0	COG0845@1|root,COG0845@2|Bacteria,1GCFD@1117|Cyanobacteria,1HF90@1150|Oscillatoriales	1117|Cyanobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6657754_1	794903.OPIT5_27940	9.729e-09	57.0	COG1595@1|root,COG1595@2|Bacteria,46YS4@74201|Verrucomicrobia,3K8W5@414999|Opitutae	414999|Opitutae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
TH3_k127_6657754_0	1499967.BAYZ01000097_gene4350	4.286e-97	333.0	COG4826@1|root,COG4826@2|Bacteria,2NQVB@2323|unclassified Bacteria	2|Bacteria	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
TH3_k127_6773412_6	1232437.KL661961_gene3016	2.148e-08	65.0	COG0764@1|root,COG0764@2|Bacteria,1NNU2@1224|Proteobacteria,437EX@68525|delta/epsilon subdivisions,2X2M8@28221|Deltaproteobacteria,2MP7V@213118|Desulfobacterales	28221|Deltaproteobacteria	I	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA
TH3_k127_6773412_4	443143.GM18_4060	2.116e-14	82.0	COG2834@1|root,COG2834@2|Bacteria,1N3XP@1224|Proteobacteria,42TP4@68525|delta/epsilon subdivisions,2WQR3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA
TH3_k127_6773412_1	1347393.HG726029_gene2088	1.466e-46	180.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,2FR15@200643|Bacteroidia,4AP6F@815|Bacteroidaceae	976|Bacteroidetes	G	Polysaccharide deacetylase	pgdA	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	DUF3298,Polysacc_deac_1
TH3_k127_6773412_0	575615.HMPREF0670_01520	2.224e-86	314.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,2FPUI@200643|Bacteroidia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_2,Ketoacyl-synt_C,ketoacyl-synt
TH3_k127_6773412_3	1121918.ARWE01000001_gene3128	8.476e-24	105.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,42V26@68525|delta/epsilon subdivisions,2WQ0Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	acpP-1	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TH3_k127_6773412_5	555779.Dthio_PD0800	1.263e-08	64.0	COG0304@1|root,COG0304@2|Bacteria,1R0WN@1224|Proteobacteria,43D2H@68525|delta/epsilon subdivisions,2X89P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ketoacyl-synt
TH3_k127_6773412_2	443143.GM18_4055	4.983e-44	166.0	COG0304@1|root,COG0304@2|Bacteria,1RAFK@1224|Proteobacteria,42R69@68525|delta/epsilon subdivisions,2WMWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TH3_k127_6775855_4	330214.NIDE3598	3.622e-69	239.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
TH3_k127_6775855_1	330214.NIDE0049	2.687e-107	352.0	COG1028@1|root,COG1028@2|Bacteria,3J0J6@40117|Nitrospirae	330214.NIDE0049|-	IQ	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
TH3_k127_6775855_2	330214.NIDE0047	1.294e-93	310.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	tdsD	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
TH3_k127_6775855_0	1288494.EBAPG3_430	8.533e-180	575.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,372JJ@32003|Nitrosomonadales	28216|Betaproteobacteria	MU	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
TH3_k127_6775855_3	330214.NIDE3474	7.92e-72	246.0	COG0841@1|root,COG0841@2|Bacteria,3J0FA@40117|Nitrospirae	40117|Nitrospirae	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138,ko:K19585	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718,M00767	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.47	-	-	ACR_tran
TH3_k127_6790068_1	1123508.JH636439_gene1118	2.179e-226	709.0	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TH3_k127_6790068_19	402777.KB235903_gene687	4.973e-51	185.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
TH3_k127_6790068_4	880073.Calab_3423	3.302e-157	515.0	COG3525@1|root,COG3525@2|Bacteria,2NNQC@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b,PA14
TH3_k127_6790068_21	180332.JTGN01000003_gene1997	1.334e-40	169.0	COG0407@1|root,COG0407@2|Bacteria,1VEQ3@1239|Firmicutes,24RQ2@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
TH3_k127_6790068_13	443143.GM18_2242	6.237e-103	356.0	COG2730@1|root,COG2730@2|Bacteria,1R4XH@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
TH3_k127_6790068_14	794903.OPIT5_03205	3.071e-91	306.0	COG0689@1|root,COG0689@2|Bacteria,46U55@74201|Verrucomicrobia,3K7EN@414999|Opitutae	414999|Opitutae	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
TH3_k127_6790068_23	1048339.KB913029_gene3814	2.827e-25	113.0	COG0406@1|root,COG0406@2|Bacteria,2HUBQ@201174|Actinobacteria	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
TH3_k127_6790068_20	443143.GM18_0270	4.453e-43	170.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,42NSS@68525|delta/epsilon subdivisions,2WIVV@28221|Deltaproteobacteria,43UAF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
TH3_k127_6790068_25	903818.KI912268_gene3014	1.514e-18	99.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,NPCBM_assoc
TH3_k127_6790068_27	1303518.CCALI_02036	7.49e-14	80.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_6790068_10	489825.LYNGBM3L_09400	1.065e-117	396.0	COG1696@1|root,COG1696@2|Bacteria,1G2RR@1117|Cyanobacteria,1H9BT@1150|Oscillatoriales	1117|Cyanobacteria	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
TH3_k127_6790068_6	1191523.MROS_1318	3.455e-132	440.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
TH3_k127_6790068_11	497964.CfE428DRAFT_6050	1.039e-116	382.0	COG0657@1|root,COG0657@2|Bacteria,46SRP@74201|Verrucomicrobia	74201|Verrucomicrobia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
TH3_k127_6790068_17	794903.OPIT5_11905	5.283e-75	257.0	COG1704@1|root,COG1704@2|Bacteria,46V9M@74201|Verrucomicrobia,3K7DK@414999|Opitutae	414999|Opitutae	S	PFAM LemA family protein	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
TH3_k127_6790068_5	886293.Sinac_6493	8.506e-157	517.0	COG0501@1|root,COG0501@2|Bacteria,2IYND@203682|Planctomycetes	203682|Planctomycetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TH3_k127_6790068_24	1396141.BATP01000024_gene851	6.181e-19	90.0	2EM29@1|root,33ERR@2|Bacteria,46WJK@74201|Verrucomicrobia,2IWEX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6790068_28	913325.N799_06220	3.245e-12	79.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,1RRRP@1236|Gammaproteobacteria,1X406@135614|Xanthomonadales	135614|Xanthomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TH3_k127_6790068_3	1396141.BATP01000024_gene848	8.779e-166	539.0	COG0845@1|root,COG0845@2|Bacteria,46SVD@74201|Verrucomicrobia,2IUGZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347,HlyD_D23
TH3_k127_6790068_0	1396141.BATP01000024_gene849	0.0	1744.0	COG3696@1|root,COG3696@2|Bacteria,46SJ1@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
TH3_k127_6790068_22	1403819.BATR01000123_gene4356	8.563e-33	139.0	28KDQ@1|root,2ZA05@2|Bacteria,46VJS@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6790068_29	376686.Fjoh_2192	1.488e-09	67.0	COG2010@1|root,COG2010@2|Bacteria,4NXZT@976|Bacteroidetes,1I673@117743|Flavobacteriia,2NX4B@237|Flavobacterium	976|Bacteroidetes	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHC
TH3_k127_6790068_8	926550.CLDAP_13850	1.44e-129	424.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi	2|Bacteria	E	PFAM aminotransferase class V	phnW	GO:0003674,GO:0003824	2.5.1.49,2.6.1.37,3.11.1.1	ko:K01740,ko:K03430,ko:K05306	ko00270,ko00440,ko01100,ko01120,map00270,map00440,map01100,map01120	-	R00747,R01287,R04152,R04859	RC00008,RC00020,RC00062,RC00368,RC02821,RC02848	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
TH3_k127_6790068_7	1122135.KB893134_gene3491	3.472e-131	432.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2TT6G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TH3_k127_6790068_12	6500.XP_005099940.1	2.037e-116	381.0	COG0637@1|root,2QU58@2759|Eukaryota,39WII@33154|Opisthokonta,3BF9K@33208|Metazoa,3D4RC@33213|Bilateria	33208|Metazoa	S	Haloacid dehalogenase-like hydrolase	-	-	3.11.1.1	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R00747	RC00368	ko00000,ko00001,ko01000	-	-	-	HAD_2
TH3_k127_6790068_2	44056.XP_009033642.1	1.597e-178	571.0	COG0160@1|root,KOG1403@2759|Eukaryota	2759|Eukaryota	E	ethanolamine-phosphate phospho-lyase activity	-	-	4.2.3.2	ko:K14286	ko00564,ko01100,map00564,map01100	-	R00748	RC00369	ko00000,ko00001,ko01000	-	-	-	Aminotran_3,Peptidase_M23
TH3_k127_6790068_26	329726.AM1_2164	1.579e-16	82.0	COG1100@1|root,COG2319@1|root,COG4916@1|root,COG1100@2|Bacteria,COG2319@2|Bacteria,COG4916@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
TH3_k127_6790068_30	247490.KSU1_D0453	6.142e-05	47.0	2EGSE@1|root,33AII@2|Bacteria,2J3TB@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6790068_15	1142394.PSMK_12900	1.963e-86	310.0	COG2103@1|root,COG2103@2|Bacteria	2|Bacteria	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	-	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	-
TH3_k127_6790068_18	382464.ABSI01000011_gene2535	2.471e-53	194.0	COG0233@1|root,COG0233@2|Bacteria,46V49@74201|Verrucomicrobia,2IUA0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
TH3_k127_6790068_31	481448.Minf_0311	0.0001275	48.0	COG2919@1|root,COG2919@2|Bacteria,46ZEA@74201|Verrucomicrobia,37GXB@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
TH3_k127_6790068_16	240016.ABIZ01000001_gene4459	7.525e-79	273.0	COG2103@1|root,COG2971@1|root,COG2103@2|Bacteria,COG2971@2|Bacteria,46SJI@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,SIS_2
TH3_k127_6790068_9	697284.ERIC2_c41250	3.58e-125	417.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,26RSI@186822|Paenibacillaceae	91061|Bacilli	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
TH3_k127_6790074_27	176275.XP_008598598.1	0.0005787	45.0	2DBUV@1|root,2S5IQ@2759|Eukaryota,3A2YX@33154|Opisthokonta,3P2XM@4751|Fungi,3QUGU@4890|Ascomycota,219D0@147550|Sordariomycetes,3TIKY@5125|Hypocreales	4751|Fungi	S	PX domain	-	-	-	-	-	-	-	-	-	-	-	-	PX
TH3_k127_6790074_22	156889.Mmc1_2862	2.873e-37	161.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
TH3_k127_6790074_8	583355.Caka_0705	1.066e-172	569.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_6790074_17	579405.Dd703_0239	1.218e-77	269.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,1RMAC@1236|Gammaproteobacteria,2JCM1@204037|Dickeya	1236|Gammaproteobacteria	S	TIGRFAM RarD protein, DMT superfamily transporter	rarD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
TH3_k127_6790074_12	1123070.KB899255_gene1382	6.518e-125	421.0	COG0608@1|root,COG0608@2|Bacteria,46SNV@74201|Verrucomicrobia,2ITRD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DHHA1 domain	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
TH3_k127_6790074_15	1521187.JPIM01000037_gene3876	1.641e-98	332.0	COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi,376HN@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
TH3_k127_6790074_5	452637.Oter_3464	2.842e-176	582.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,3K770@414999|Opitutae	414999|Opitutae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
TH3_k127_6790074_23	289376.THEYE_A0281	5.764e-20	95.0	COG1862@1|root,COG1862@2|Bacteria,3J0UB@40117|Nitrospirae	40117|Nitrospirae	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
TH3_k127_6790074_9	240016.ABIZ01000001_gene3247	1.16e-142	462.0	COG0075@1|root,COG0075@2|Bacteria,46SCI@74201|Verrucomicrobia,2IU5S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
TH3_k127_6790074_20	497964.CfE428DRAFT_5371	9.899e-57	210.0	COG4121@1|root,COG4121@2|Bacteria	2|Bacteria	E	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363	2.1.1.61,2.1.1.72,2.4.2.29,4.2.1.151	ko:K00773,ko:K07319,ko:K11782,ko:K15461	ko00130,ko01110,map00130,map01110	-	R00601,R03789,R08702,R10209,R10666	RC00003,RC00053,RC00060,RC00063,RC01483,RC03232	ko00000,ko00001,ko01000,ko02048,ko03016	-	-	-	DAO,Methyltransf_30
TH3_k127_6790074_25	671143.DAMO_2125	1.263e-14	77.0	COG0724@1|root,COG0724@2|Bacteria,2NPT0@2323|unclassified Bacteria	2|Bacteria	S	RNA recognition motif	rbpD	-	-	-	-	-	-	-	-	-	-	-	RRM_1
TH3_k127_6790074_24	382464.ABSI01000001_gene4245	1.135e-18	94.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
TH3_k127_6790074_16	497964.CfE428DRAFT_2716	2.03e-96	326.0	COG0533@1|root,COG0533@2|Bacteria,46SEH@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
TH3_k127_6790074_13	497964.CfE428DRAFT_2715	2.907e-124	412.0	COG0793@1|root,COG0793@2|Bacteria,46SM7@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
TH3_k127_6790074_3	497964.CfE428DRAFT_0809	2.392e-181	576.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TYP@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6790074_1	1396141.BATP01000006_gene5477	2.727e-260	825.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,46TDA@74201|Verrucomicrobia,2IV8Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TH3_k127_6790074_19	1111479.AXAR01000001_gene213	8.371e-61	222.0	COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,278V8@186823|Alicyclobacillaceae	91061|Bacilli	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TH3_k127_6790074_10	521674.Plim_2636	4.165e-141	464.0	COG3250@1|root,COG3250@2|Bacteria,2J54D@203682|Planctomycetes	203682|Planctomycetes	G	Pfam:DUF303	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
TH3_k127_6790074_7	497964.CfE428DRAFT_6471	9.558e-173	550.0	COG0508@1|root,COG0508@2|Bacteria,46UHU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TH3_k127_6790074_6	497964.CfE428DRAFT_6472	5.509e-174	550.0	COG0022@1|root,COG0022@2|Bacteria,46UID@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
TH3_k127_6790074_11	497964.CfE428DRAFT_6473	3.736e-131	432.0	COG1071@1|root,COG1071@2|Bacteria,46UAY@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
TH3_k127_6790074_18	234267.Acid_6247	2.686e-73	263.0	COG0673@1|root,COG0673@2|Bacteria,3Y39X@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_6790074_21	247490.KSU1_D0514	1.318e-41	179.0	COG3055@1|root,COG3204@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Big_5,Exo_endo_phos,He_PIG,HemolysinCabind,LTD,Laminin_G_3,Malectin,PA14
TH3_k127_6790074_0	1396141.BATP01000030_gene3715	1.747e-279	934.0	COG2010@1|root,COG2312@1|root,COG5337@1|root,COG5563@1|root,COG2010@2|Bacteria,COG2312@2|Bacteria,COG5337@2|Bacteria,COG5563@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
TH3_k127_6790074_14	595460.RRSWK_04460	5.051e-120	391.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
TH3_k127_6790074_26	595460.RRSWK_06357	8.78e-07	60.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,PmoA
TH3_k127_6790074_2	886293.Sinac_5476	8.324e-209	680.0	COG0153@1|root,COG1207@1|root,COG0153@2|Bacteria,COG1207@2|Bacteria	2|Bacteria	M	glucosamine-1-phosphate N-acetyltransferase activity	galK	-	2.3.1.209,2.7.1.157,2.7.1.6	ko:K00849,ko:K02406,ko:K18674,ko:K21379	ko00052,ko00520,ko01100,ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map00052,map00520,map01100,map02020,map02040,map04621,map04626,map05132,map05134	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko02035,ko04147	-	-	-	DUF4954,GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg,Hexapep
TH3_k127_6790074_4	1288963.ADIS_1775	3.196e-177	567.0	COG1621@1|root,COG1621@2|Bacteria,4P0AM@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6818239_7	1183438.GKIL_4380	1.269e-87	330.0	COG1404@1|root,COG1404@2|Bacteria,1G8UV@1117|Cyanobacteria	1117|Cyanobacteria	O	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,VCBS
TH3_k127_6818239_17	261292.Nit79A3_2710	2.733e-26	128.0	COG3468@1|root,COG3468@2|Bacteria,1QUZ3@1224|Proteobacteria	1224|Proteobacteria	MU	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,TIG
TH3_k127_6818239_8	251221.35213566	4.804e-72	279.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6818239_20	682795.AciX8_3725	4.748e-10	74.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
TH3_k127_6818239_5	1353529.M899_0311	2.215e-124	404.0	COG1951@1|root,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,42MC7@68525|delta/epsilon subdivisions,2WKIV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
TH3_k127_6818239_11	1121920.AUAU01000009_gene1881	6.962e-56	227.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
TH3_k127_6818239_12	102129.Lepto7375DRAFT_5814	2.958e-48	202.0	COG2755@1|root,COG2931@1|root,COG2755@2|Bacteria,COG2931@2|Bacteria,1G0DX@1117|Cyanobacteria,1H8AY@1150|Oscillatoriales	1117|Cyanobacteria	Q	COG2931 RTX toxins and related Ca2 -binding	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF11,DUF4347,HemolysinCabind,Laminin_G_3,VCBS
TH3_k127_6818239_21	1379698.RBG1_1C00001G1428	1.007e-05	61.0	COG2911@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NS5I@2323|unclassified Bacteria	2|Bacteria	U	FlgD Ig-like domain	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Cytochrome_C554,DUF11,FlgD_ig,PKD,SLH
TH3_k127_6818239_4	208439.AJAP_24615	3.438e-140	506.0	COG1361@1|root,COG4935@1|root,COG1361@2|Bacteria,COG4935@2|Bacteria,2I2W6@201174|Actinobacteria,4EDRS@85010|Pseudonocardiales	201174|Actinobacteria	MO	Proprotein convertase P-domain	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
TH3_k127_6818239_6	886293.Sinac_6918	1.94e-107	364.0	COG2133@1|root,COG3386@1|root,COG2133@2|Bacteria,COG3386@2|Bacteria,2IXAF@203682|Planctomycetes	203682|Planctomycetes	G	glucose sorbosone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	DUF1080,GSDH,SGL
TH3_k127_6818239_14	331869.BAL199_20935	2.04e-33	139.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,4BSDR@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
TH3_k127_6818239_3	1267533.KB906733_gene3043	8.183e-181	582.0	COG1574@1|root,COG1574@2|Bacteria,3Y2UF@57723|Acidobacteria,2JIRH@204432|Acidobacteriia	204432|Acidobacteriia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
TH3_k127_6818239_13	1123242.JH636434_gene4667	1.035e-44	177.0	2F56K@1|root,33XTB@2|Bacteria,2J30K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6818239_22	1283283.ATXA01000005_gene2190	6.493e-05	48.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4ESQP@85013|Frankiales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	int	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
TH3_k127_6818239_10	1191523.MROS_0856	9.244e-57	203.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	-	-	-	ko:K03976,ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
TH3_k127_6818239_2	1123242.JH636434_gene4307	1.755e-203	647.0	COG1032@1|root,COG1032@2|Bacteria,2J1W3@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
TH3_k127_6818239_16	313628.LNTAR_18430	2.138e-28	120.0	COG1372@1|root,COG1372@2|Bacteria	2|Bacteria	L	intein-mediated protein splicing	-	-	1.1.98.6,3.6.3.14,3.6.3.15,4.1.1.35	ko:K02117,ko:K08678,ko:K21636	ko00190,ko00230,ko00240,ko00520,ko01100,map00190,map00230,map00240,map00520,map01100	M00053,M00159,M00361	R01384,R11633,R11634,R11635,R11636	RC00508,RC00613	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-cone,DUF4280,Intein_splicing,LAGLIDADG_3,NRDD,PT-HINT
TH3_k127_6818239_9	765420.OSCT_3130	2.06e-67	245.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
TH3_k127_6818239_19	113355.CM001775_gene3666	9.069e-14	84.0	COG1404@1|root,COG1404@2|Bacteria,1G1G8@1117|Cyanobacteria	1117|Cyanobacteria	O	Subtilisin-like serine protease	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
TH3_k127_6818239_15	261292.Nit79A3_1788	9.597e-33	148.0	28HU5@1|root,2Z80X@2|Bacteria,1R55N@1224|Proteobacteria,2VI32@28216|Betaproteobacteria,372Y4@32003|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM TIGR03790 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6818239_1	1396141.BATP01000032_gene4274	7.581e-215	687.0	COG1073@1|root,COG1073@2|Bacteria,46Z70@74201|Verrucomicrobia,2IWQ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
TH3_k127_6818239_0	497964.CfE428DRAFT_3901	8.442e-230	729.0	COG0210@1|root,COG0210@2|Bacteria,46S8H@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM UvrD REP helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
TH3_k127_6829990_42	1192034.CAP_8203	2.718e-31	145.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YU2V@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
TH3_k127_6829990_53	452637.Oter_1999	7.41e-14	87.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
TH3_k127_6829990_15	935845.JADQ01000029_gene1230	3.01e-123	444.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
TH3_k127_6829990_60	886293.Sinac_0949	1.251e-07	53.0	COG3250@1|root,COG3250@2|Bacteria,2IWTW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_43
TH3_k127_6829990_29	1396141.BATP01000030_gene3773	4.663e-80	273.0	COG3250@1|root,COG3387@1|root,COG3250@2|Bacteria,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1793,DUF4964,DUF4965,DUF5127,RicinB_lectin_2
TH3_k127_6829990_2	661478.OP10G_2213	2.198e-315	998.0	COG1621@1|root,COG4354@1|root,COG1621@2|Bacteria,COG4354@2|Bacteria	2|Bacteria	G	intracellular protein transport	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,DUF608,Glyco_hydr_116N,VCBS
TH3_k127_6829990_57	1046714.AMRX01000008_gene918	4.284e-11	65.0	COG4030@1|root,COG4030@2|Bacteria,1NSDB@1224|Proteobacteria,1SC1R@1236|Gammaproteobacteria,469NN@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
TH3_k127_6829990_56	1303518.CCALI_02295	6.809e-13	78.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_6829990_51	1303518.CCALI_02638	5.14e-16	89.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_6829990_14	861299.J421_6202	4.704e-128	424.0	COG1064@1|root,COG1064@2|Bacteria,1ZSXS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zinc-binding dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
TH3_k127_6829990_54	1303518.CCALI_00340	2.432e-13	79.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_6829990_65	864051.BurJ1DRAFT_1395	0.0003976	51.0	2E8G8@1|root,332UI@2|Bacteria,1N7XZ@1224|Proteobacteria,2W3AB@28216|Betaproteobacteria,1KNT8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
TH3_k127_6829990_37	1500893.JQNB01000001_gene1609	5.403e-48	177.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,1SBBF@1236|Gammaproteobacteria,1XDAF@135614|Xanthomonadales	135614|Xanthomonadales	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
TH3_k127_6829990_52	1132855.KB913035_gene572	2.284e-14	77.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,2VUVV@28216|Betaproteobacteria,2KMXM@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	-	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
TH3_k127_6829990_19	1396141.BATP01000060_gene4695	4.238e-99	338.0	COG0546@1|root,COG1051@1|root,COG0546@2|Bacteria,COG1051@2|Bacteria,46VY5@74201|Verrucomicrobia,2IUEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,NUDIX
TH3_k127_6829990_7	478741.JAFS01000001_gene1962	3.775e-169	551.0	COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia,37G93@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TH3_k127_6829990_38	667014.Thein_1367	4.513e-42	162.0	COG0563@1|root,COG0563@2|Bacteria,2GI9A@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Adenylate kinase	-	-	-	-	-	-	-	-	-	-	-	-	ADK
TH3_k127_6829990_16	1166018.FAES_2374	2.049e-119	388.0	COG4821@1|root,COG4821@2|Bacteria,4NHQW@976|Bacteroidetes,47MJI@768503|Cytophagia	976|Bacteroidetes	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
TH3_k127_6829990_9	1499967.BAYZ01000093_gene4011	8.709e-159	509.0	COG0673@1|root,COG0673@2|Bacteria,2NRE6@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.99.28	ko:K00118	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA
TH3_k127_6829990_30	1403819.BATR01000118_gene4116	8.163e-76	265.0	COG1940@1|root,COG1940@2|Bacteria,46T0E@74201|Verrucomicrobia	74201|Verrucomicrobia	GK	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	ROK
TH3_k127_6829990_26	886293.Sinac_3103	1.723e-83	287.0	COG1082@1|root,COG1082@2|Bacteria,2IZ3D@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_6829990_6	497964.CfE428DRAFT_4420	5.16e-217	685.0	COG3119@1|root,COG3119@2|Bacteria,46V0M@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
TH3_k127_6829990_5	886293.Sinac_3461	7.609e-224	707.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
TH3_k127_6829990_34	1313301.AUGC01000009_gene1068	2.968e-58	212.0	COG0394@1|root,COG0394@2|Bacteria,4NE8C@976|Bacteroidetes	976|Bacteroidetes	T	protein tyrosine phosphatase	-	-	1.20.4.1,3.1.3.48	ko:K01104,ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	-
TH3_k127_6829990_10	1123242.JH636434_gene4668	1.987e-157	520.0	COG1520@1|root,COG3221@1|root,COG1520@2|Bacteria,COG3221@2|Bacteria,2J1S1@203682|Planctomycetes	203682|Planctomycetes	P	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_6829990_39	1210884.HG799462_gene8243	1.429e-38	160.0	2F56K@1|root,33XTB@2|Bacteria,2J30K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6829990_46	269482.Bcep1808_6245	2.641e-21	96.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2VI1H@28216|Betaproteobacteria,1K3UX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
TH3_k127_6829990_8	497964.CfE428DRAFT_4290	3.332e-167	535.0	COG0448@1|root,COG0448@2|Bacteria,46SG2@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TH3_k127_6829990_21	794903.OPIT5_28075	1.995e-93	312.0	COG1137@1|root,COG1137@2|Bacteria,46SDI@74201|Verrucomicrobia,3K77F@414999|Opitutae	414999|Opitutae	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
TH3_k127_6829990_17	497964.CfE428DRAFT_4273	6.93e-107	355.0	COG1493@1|root,COG1493@2|Bacteria,46S64@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
TH3_k127_6829990_41	497964.CfE428DRAFT_4274	2.231e-32	130.0	COG1925@1|root,COG1925@2|Bacteria,46T6C@74201|Verrucomicrobia	74201|Verrucomicrobia	G	TIGRFAM phosphocarrier, HPr family	fruB	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
TH3_k127_6829990_33	278957.ABEA03000130_gene1706	1.215e-62	220.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigE1	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TH3_k127_6829990_20	278957.ABEA03000130_gene1703	8.509e-94	319.0	COG1313@1|root,COG1313@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Radical_SAM
TH3_k127_6829990_4	278957.ABEA03000130_gene1701	8.64e-241	754.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	ycf46	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
TH3_k127_6829990_50	278957.ABEA03000130_gene1699	8.648e-18	84.0	2EJWH@1|root,33DM6@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2997)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2997
TH3_k127_6829990_27	278957.ABEA03000130_gene1697	1.952e-83	288.0	COG0457@1|root,COG0457@2|Bacteria	278957.ABEA03000130_gene1697|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6829990_11	278957.ABEA03000130_gene1696	9.179e-146	478.0	COG2805@1|root,COG2805@2|Bacteria,46S5Q@74201|Verrucomicrobia,3K79X@414999|Opitutae	2|Bacteria	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
TH3_k127_6829990_25	497964.CfE428DRAFT_3544	7.406e-85	294.0	COG1173@1|root,COG1173@2|Bacteria,46SN0@74201|Verrucomicrobia	74201|Verrucomicrobia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
TH3_k127_6829990_28	1192034.CAP_8072	3.761e-83	286.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,43AFB@68525|delta/epsilon subdivisions,2X5XK@28221|Deltaproteobacteria,2Z2YK@29|Myxococcales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	appB	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
TH3_k127_6829990_12	1403819.BATR01000065_gene1925	2.191e-143	478.0	COG4166@1|root,COG4166@2|Bacteria,46SBG@74201|Verrucomicrobia,2ITVI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
TH3_k127_6829990_58	278957.ABEA03000211_gene3535	1.148e-10	67.0	COG1314@1|root,COG1314@2|Bacteria,46T75@74201|Verrucomicrobia,3K89V@414999|Opitutae	414999|Opitutae	U	PFAM Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
TH3_k127_6829990_24	452637.Oter_3825	2.035e-86	292.0	COG0149@1|root,COG0149@2|Bacteria,46SNB@74201|Verrucomicrobia,3K7RD@414999|Opitutae	414999|Opitutae	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
TH3_k127_6829990_13	1396418.BATQ01000076_gene732	3.827e-142	467.0	COG0126@1|root,COG0126@2|Bacteria,46SI9@74201|Verrucomicrobia,2ITXY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
TH3_k127_6829990_47	497964.CfE428DRAFT_4171	3.29e-20	98.0	2ETM2@1|root,33M4S@2|Bacteria,46WNN@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6829990_59	794903.OPIT5_29655	4.501e-10	71.0	COG4968@1|root,COG4968@2|Bacteria	794903.OPIT5_29655|-	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6829990_43	1403819.BATR01000069_gene2089	2.035e-29	125.0	COG4968@1|root,COG4968@2|Bacteria,46VT8@74201|Verrucomicrobia,2IW29@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
TH3_k127_6829990_23	497964.CfE428DRAFT_4175	8.438e-87	296.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_6829990_36	1142394.PSMK_14730	7.353e-56	207.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
TH3_k127_6829990_1	278957.ABEA03000202_gene4301	0.0	1073.0	COG0187@1|root,COG0187@2|Bacteria,46TW5@74201|Verrucomicrobia,3K7GR@414999|Opitutae	414999|Opitutae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TH3_k127_6829990_0	497964.CfE428DRAFT_4373	0.0	1112.0	COG0188@1|root,COG0188@2|Bacteria,46SBE@74201|Verrucomicrobia	74201|Verrucomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
TH3_k127_6829990_31	383372.Rcas_1067	1.363e-72	253.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,376ZA@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
TH3_k127_6829990_32	309799.DICTH_0179	6.057e-64	237.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Pkinase,VCBS
TH3_k127_6829990_49	589924.Ferp_2052	8.694e-19	91.0	arCOG03086@1|root,arCOG03086@2157|Archaea,2Y7EV@28890|Euryarchaeota,247AD@183980|Archaeoglobi	183980|Archaeoglobi	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
TH3_k127_6829990_48	330214.NIDE2936	5.49e-19	89.0	COG1598@1|root,COG1598@2|Bacteria,3J1EZ@40117|Nitrospirae	40117|Nitrospirae	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6829990_44	595460.RRSWK_04460	7.081e-26	108.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
TH3_k127_6829990_3	1396418.BATQ01000136_gene3697	3.274e-288	897.0	COG0665@1|root,COG0665@2|Bacteria,46TKJ@74201|Verrucomicrobia,2IWQZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
TH3_k127_6829990_18	278957.ABEA03000027_gene1659	2.361e-101	344.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,46UGX@74201|Verrucomicrobia,3K7XD@414999|Opitutae	414999|Opitutae	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
TH3_k127_6829990_35	945713.IALB_0431	5.572e-58	213.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
TH3_k127_6829990_22	1296990.H845_3380	6.315e-92	315.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria,2JU31@204441|Rhodospirillales	204441|Rhodospirillales	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
TH3_k127_6829990_55	522306.CAP2UW1_3973	2.814e-13	71.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
TH3_k127_6885102_2	316274.Haur_0788	1.601e-06	59.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
TH3_k127_6885102_0	497964.CfE428DRAFT_0111	6.612e-32	144.0	2CMJG@1|root,32SEZ@2|Bacteria,46T0G@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6885102_1	869210.Marky_1921	9.624e-23	105.0	COG0517@1|root,COG5485@1|root,COG0517@2|Bacteria,COG5485@2|Bacteria,1WK3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
TH3_k127_6892980_3	69293.ENSGACP00000022592	5.318e-10	65.0	KOG1215@1|root,KOG1215@2759|Eukaryota,38B6M@33154|Opisthokonta,3B9HR@33208|Metazoa,3CTYV@33213|Bilateria,47YVC@7711|Chordata,497BX@7742|Vertebrata,49TNF@7898|Actinopterygii	33208|Metazoa	T	lipoprotein receptor-related protein	LRP4	GO:0000902,GO:0000904,GO:0001655,GO:0001822,GO:0001932,GO:0001934,GO:0001941,GO:0001942,GO:0003002,GO:0003674,GO:0004888,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0007166,GO:0007267,GO:0007275,GO:0007389,GO:0007399,GO:0007416,GO:0007528,GO:0008104,GO:0008150,GO:0008544,GO:0009653,GO:0009790,GO:0009798,GO:0009887,GO:0009888,GO:0009893,GO:0009950,GO:0009953,GO:0009954,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0010562,GO:0010604,GO:0010646,GO:0010648,GO:0010721,GO:0010769,GO:0010771,GO:0010975,GO:0010977,GO:0014069,GO:0016020,GO:0016043,GO:0016055,GO:0016358,GO:0017147,GO:0019220,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022404,GO:0022405,GO:0022603,GO:0022604,GO:0022607,GO:0023051,GO:0023052,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030178,GO:0030182,GO:0030278,GO:0030279,GO:0030326,GO:0030424,GO:0030425,GO:0030971,GO:0031175,GO:0031323,GO:0031325,GO:0031344,GO:0031345,GO:0031399,GO:0031401,GO:0031594,GO:0032268,GO:0032270,GO:0032279,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033267,GO:0034185,GO:0034613,GO:0035107,GO:0035108,GO:0035113,GO:0036477,GO:0038023,GO:0040007,GO:0042303,GO:0042325,GO:0042327,GO:0042475,GO:0042476,GO:0042633,GO:0042733,GO:0042802,GO:0042803,GO:0042813,GO:0042995,GO:0043005,GO:0043025,GO:0043113,GO:0043226,GO:0043235,GO:0043588,GO:0043679,GO:0043933,GO:0044085,GO:0044091,GO:0044297,GO:0044306,GO:0044332,GO:0044425,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045202,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045937,GO:0046983,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048589,GO:0048598,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048736,GO:0048812,GO:0048813,GO:0048856,GO:0048858,GO:0048869,GO:0050730,GO:0050731,GO:0050767,GO:0050768,GO:0050770,GO:0050771,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050808,GO:0050896,GO:0051093,GO:0051124,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051262,GO:0051290,GO:0051291,GO:0051641,GO:0051668,GO:0051716,GO:0051960,GO:0051961,GO:0060070,GO:0060089,GO:0060173,GO:0060255,GO:0060284,GO:0060341,GO:0060429,GO:0060828,GO:0061024,GO:0065003,GO:0065007,GO:0065008,GO:0070727,GO:0071340,GO:0071709,GO:0071840,GO:0071944,GO:0072001,GO:0072657,GO:0080090,GO:0090090,GO:0097060,GO:0097090,GO:0097104,GO:0097105,GO:0097110,GO:0097447,GO:0097458,GO:0098590,GO:0098773,GO:0098793,GO:0098794,GO:0098984,GO:0099054,GO:0099068,GO:0099172,GO:0099173,GO:0099175,GO:0099572,GO:0120025,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0150034,GO:0198738,GO:1901626,GO:1901628,GO:1901629,GO:1901631,GO:1903827,GO:1903829,GO:1903909,GO:1903911,GO:1904393,GO:1904395,GO:1904396,GO:1904398,GO:1905114,GO:1905475,GO:1905477,GO:1990709,GO:1990782,GO:2000026	-	ko:K20051	-	-	-	-	ko00000,ko04131	-	-	-	EGF_CA,FXa_inhibition,Ldl_recept_a,Ldl_recept_b,cEGF
TH3_k127_6892980_1	218284.CCDN010000001_gene723	3.367e-32	143.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus	91061|Bacilli	S	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
TH3_k127_6892980_0	368408.Tpen_1559	3.864e-128	431.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6892980_2	641524.ADICYQ_1594	6.059e-22	105.0	COG1082@1|root,COG1082@2|Bacteria,4NFKF@976|Bacteroidetes,47P9Y@768503|Cytophagia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_6918861_24	1081644.IMCC13023_01510	6.884e-24	108.0	COG1811@1|root,COG1811@2|Bacteria,2GM75@201174|Actinobacteria	201174|Actinobacteria	S	Na channel or pump	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
TH3_k127_6918861_0	497964.CfE428DRAFT_2523	0.0	1400.0	COG0209@1|root,COG0209@2|Bacteria,46SG4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
TH3_k127_6918861_12	562970.Btus_1769	1.696e-109	372.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,278SV@186823|Alicyclobacillaceae	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
TH3_k127_6918861_7	497964.CfE428DRAFT_2485	2.132e-185	587.0	COG1904@1|root,COG1904@2|Bacteria	2|Bacteria	G	glucuronate isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6918861_34	693977.Deipr_0877	0.0001629	52.0	COG4700@1|root,COG4700@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	GerE,PLDc_N,TPR_16,TPR_19,TPR_4,TPR_6,TPR_8
TH3_k127_6918861_13	1379270.AUXF01000006_gene276	8.607e-87	297.0	COG0463@1|root,COG0463@2|Bacteria,1ZT31@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
TH3_k127_6918861_23	742725.HMPREF9450_02179	1.219e-34	141.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,2FNTB@200643|Bacteroidia,22VB5@171550|Rikenellaceae	976|Bacteroidetes	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
TH3_k127_6918861_30	985053.VMUT_0013	2.679e-15	81.0	COG5550@1|root,arCOG03744@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6918861_16	316274.Haur_0795	1.201e-62	232.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,LuxE
TH3_k127_6918861_17	1116472.MGMO_10c00180	1.413e-61	220.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1RPXT@1236|Gammaproteobacteria,1XDRK@135618|Methylococcales	135618|Methylococcales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
TH3_k127_6918861_26	1197130.BAFM01000020_gene2812	2.737e-21	108.0	COG0477@1|root,arCOG00130@2157|Archaea,2XVPQ@28890|Euryarchaeota,23TTF@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TH3_k127_6918861_15	1134413.ANNK01000094_gene900	2.99e-69	252.0	COG1012@1|root,COG1012@2|Bacteria,1TSYP@1239|Firmicutes,4HE2I@91061|Bacilli,1ZCXK@1386|Bacillus	91061|Bacilli	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
TH3_k127_6918861_20	198628.Dda3937_00205	1.181e-45	176.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,2JE6U@204037|Dickeya	1236|Gammaproteobacteria	H	PFAM 6-pyruvoyl tetrahydropterin synthase and	queD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	iECIAI39_1322.ECIAI39_2947,iUTI89_1310.UTI89_C3129,ic_1306.c3324	PTPS
TH3_k127_6918861_6	1403819.BATR01000164_gene5622	9.553e-223	711.0	COG0465@1|root,COG0465@2|Bacteria,46SB7@74201|Verrucomicrobia,2ITNZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
TH3_k127_6918861_21	382464.ABSI01000021_gene406	7.271e-41	156.0	COG1528@1|root,COG1528@2|Bacteria	2|Bacteria	P	ferric iron binding	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
TH3_k127_6918861_18	1123070.KB899257_gene2284	1.243e-60	216.0	COG0036@1|root,COG0036@2|Bacteria,46SVX@74201|Verrucomicrobia,2IU4U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
TH3_k127_6918861_11	1128421.JAGA01000003_gene2773	1.204e-118	401.0	COG1109@1|root,COG1109@2|Bacteria,2NNTH@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	femD	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TH3_k127_6918861_25	278957.ABEA03000060_gene3088	8.993e-22	100.0	COG5074@1|root,COG5074@2|Bacteria,46W5A@74201|Verrucomicrobia,3K8CX@414999|Opitutae	414999|Opitutae	U	SNAP receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6918861_10	383372.Rcas_0519	6.859e-130	438.0	COG3525@1|root,COG3525@2|Bacteria,2G609@200795|Chloroflexi,376QW@32061|Chloroflexia	32061|Chloroflexia	G	Glycoside hydrolase, family 20	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
TH3_k127_6918861_14	497964.CfE428DRAFT_2508	2.109e-77	263.0	COG0066@1|root,COG0066@2|Bacteria,46TAY@74201|Verrucomicrobia	74201|Verrucomicrobia	E	3-isopropylmalate dehydratase, small subunit	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
TH3_k127_6918861_3	661478.OP10G_1743	7.403e-274	865.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127,RicinB_lectin_2
TH3_k127_6918861_5	886293.Sinac_0949	3.539e-232	733.0	COG3250@1|root,COG3250@2|Bacteria,2IWTW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_43
TH3_k127_6918861_1	1396141.BATP01000030_gene3773	0.0	1066.0	COG3250@1|root,COG3387@1|root,COG3250@2|Bacteria,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1793,DUF4964,DUF4965,DUF5127,RicinB_lectin_2
TH3_k127_6918861_9	1158294.JOMI01000007_gene112	7.881e-166	534.0	COG5434@1|root,COG5434@2|Bacteria,4NIYD@976|Bacteroidetes,2FRQ9@200643|Bacteroidia	976|Bacteroidetes	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
TH3_k127_6918861_8	118161.KB235922_gene1342	2.203e-168	557.0	COG3420@1|root,COG3420@2|Bacteria,1GPUW@1117|Cyanobacteria,3VJI4@52604|Pleurocapsales	1117|Cyanobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TH3_k127_6918861_4	411477.PARMER_03655	3.05e-249	805.0	COG3250@1|root,COG3250@2|Bacteria,4NIBS@976|Bacteroidetes,2FPZ2@200643|Bacteroidia,22ZBT@171551|Porphyromonadaceae	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
TH3_k127_6918861_29	1173028.ANKO01000014_gene1062	8.766e-19	100.0	COG1572@1|root,COG1572@2|Bacteria,1G2VV@1117|Cyanobacteria,1HAEV@1150|Oscillatoriales	1117|Cyanobacteria	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TH3_k127_6918861_32	1121101.HMPREF1532_01485	3.614e-07	63.0	COG0860@1|root,COG0860@2|Bacteria,4PPDZ@976|Bacteroidetes,2G15H@200643|Bacteroidia,4ATKG@815|Bacteroidaceae	976|Bacteroidetes	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
TH3_k127_6918861_2	497964.CfE428DRAFT_3199	1.79e-289	896.0	COG0119@1|root,COG0119@2|Bacteria,46TI3@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
TH3_k127_6918861_31	1303518.CCALI_01797	4.752e-15	85.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10,T2SSG
TH3_k127_6918861_33	81824.XP_001748107.1	5.762e-05	51.0	COG2132@1|root,2QR4X@2759|Eukaryota,38BK4@33154|Opisthokonta	33154|Opisthokonta	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
TH3_k127_6918861_19	497964.CfE428DRAFT_3450	1.993e-58	209.0	COG2096@1|root,COG2096@2|Bacteria,46T1G@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cobalamin adenosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Cob_adeno_trans
TH3_k127_6918861_22	452637.Oter_3173	1.948e-36	145.0	2EFI3@1|root,339AJ@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
TH3_k127_6918861_28	644281.MFS40622_1510	9.5e-20	93.0	COG1985@1|root,arCOG01484@2157|Archaea,2XU47@28890|Euryarchaeota,23QM6@183939|Methanococci	183939|Methanococci	H	PFAM bifunctional deaminase-reductase domain protein	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C,Toprim_2
TH3_k127_6936965_8	1185876.BN8_02314	3.287e-50	185.0	COG1082@1|root,COG1082@2|Bacteria,4NKFY@976|Bacteroidetes,47N9K@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_6936965_4	706587.Desti_0932	1.961e-148	488.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Sodium sulphate symporter	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
TH3_k127_6936965_3	1403819.BATR01000162_gene5307	7.835e-159	508.0	COG4260@1|root,COG4260@2|Bacteria,46UVR@74201|Verrucomicrobia,2IV4M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17
TH3_k127_6936965_14	497964.CfE428DRAFT_2630	6.489e-08	60.0	COG1571@1|root,COG1571@2|Bacteria,46UI2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6936965_2	497964.CfE428DRAFT_2630	2.403e-162	525.0	COG1571@1|root,COG1571@2|Bacteria,46UI2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6936965_9	1396141.BATP01000060_gene4765	7.079e-28	133.0	COG0028@1|root,COG2730@1|root,COG2755@1|root,COG2931@1|root,COG3506@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG0028@2|Bacteria,COG2730@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3506@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
TH3_k127_6936965_0	1396141.BATP01000040_gene2082	1.494e-212	713.0	COG2247@1|root,COG3291@1|root,COG4733@1|root,COG5492@1|root,COG2247@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,46TXW@74201|Verrucomicrobia	74201|Verrucomicrobia	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	PA14
TH3_k127_6936965_13	28072.Nos7524_4621	2.368e-10	76.0	COG0823@1|root,COG2304@1|root,COG3209@1|root,COG3210@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1GQ0G@1117|Cyanobacteria,1HN8U@1161|Nostocales	1117|Cyanobacteria	MU	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,He_PIG,RHS_repeat
TH3_k127_6936965_7	313603.FB2170_10111	1.569e-57	233.0	COG3055@1|root,COG3204@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia,2PGXB@252356|Maribacter	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
TH3_k127_6936965_5	1396141.BATP01000043_gene1929	3.343e-90	341.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
TH3_k127_6936965_10	1396141.BATP01000059_gene2520	4.265e-23	119.0	COG1404@1|root,COG2133@1|root,COG3055@1|root,COG3204@1|root,COG3506@1|root,COG3897@1|root,COG4733@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3506@2|Bacteria,COG3897@2|Bacteria,COG4733@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	psrP1	-	1.11.1.5,3.1.3.8,4.2.2.2	ko:K00428,ko:K01083,ko:K01728	ko00040,ko00562,ko02024,map00040,map00562,map02024	-	R02361,R03371,R06240	RC00049,RC00078,RC00705	ko00000,ko00001,ko01000	-	-	-	GSDH,Laminin_G_3,Malectin
TH3_k127_6936965_11	1121957.ATVL01000007_gene1972	2.626e-16	96.0	COG3291@1|root,COG3291@2|Bacteria,4NW5Z@976|Bacteroidetes	976|Bacteroidetes	C	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TH3_k127_6936965_12	661478.OP10G_1071	2.171e-12	78.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_6936965_1	497964.CfE428DRAFT_4368	7.908e-211	674.0	COG1520@1|root,COG1520@2|Bacteria,46U89@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,PQQ_2,PQQ_3
TH3_k127_6936965_6	234267.Acid_6003	1.53e-58	223.0	COG2251@1|root,COG3316@1|root,COG2251@2|Bacteria,COG3316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,DDE_Tnp_IS66,HHH_5,RNase_H_2
TH3_k127_6952673_0	589865.DaAHT2_0221	8.63e-76	262.0	COG2172@1|root,COG2208@1|root,COG5002@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,COG5002@2|Bacteria,1PGCN@1224|Proteobacteria,42ZJ2@68525|delta/epsilon subdivisions,2WUYN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
TH3_k127_6952673_1	1122165.AUHS01000032_gene2254	2.436e-23	113.0	2CIHU@1|root,338F9@2|Bacteria,1NES4@1224|Proteobacteria,1STBF@1236|Gammaproteobacteria,1JD5H@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_6952673_4	1123035.ARLA01000026_gene170	0.0004358	51.0	COG0793@1|root,COG0793@2|Bacteria,4NIGU@976|Bacteroidetes,1I43H@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
TH3_k127_6952673_2	452637.Oter_1864	1.276e-19	103.0	COG3327@1|root,COG3327@2|Bacteria,46W9G@74201|Verrucomicrobia	74201|Verrucomicrobia	K	negative regulation of DNA-templated transcription, initiation	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX_C
TH3_k127_6952673_3	296587.XP_002507930.1	1.41e-16	83.0	2E1M9@1|root,2S8XU@2759|Eukaryota,37ZTR@33090|Viridiplantae,34KP7@3041|Chlorophyta	3041|Chlorophyta	S	Helicase associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HA
TH3_k127_7035329_1	344747.PM8797T_21028	1.665e-26	129.0	COG1520@1|root,COG1864@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3391@1|root,COG4935@1|root,COG5492@1|root,COG1520@2|Bacteria,COG1864@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,COG5492@2|Bacteria,2IY9M@203682|Planctomycetes	203682|Planctomycetes	Q	DNA RNA non-specific endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7035329_2	498761.HM1_0137	3.676e-23	118.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
TH3_k127_7035329_0	272123.Anacy_4407	1.029e-89	337.0	COG2931@1|root,COG5276@1|root,COG2931@2|Bacteria,COG5276@2|Bacteria,1GQ7S@1117|Cyanobacteria,1HRXM@1161|Nostocales	1117|Cyanobacteria	Q	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,HemolysinCabind,LVIVD
TH3_k127_7035329_3	6087.XP_002161070.2	6.718e-05	57.0	KOG0032@1|root,KOG0613@1|root,KOG4240@1|root,KOG0032@2759|Eukaryota,KOG0613@2759|Eukaryota,KOG4240@2759|Eukaryota,38BAS@33154|Opisthokonta,3B9IR@33208|Metazoa	33208|Metazoa	T	myosin light chain kinase activity	-	-	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	I-set,Pkinase,fn3
TH3_k127_7044601_3	335543.Sfum_3460	1.136e-08	61.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2WRDW@28221|Deltaproteobacteria,2MQPR@213462|Syntrophobacterales	28221|Deltaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TH3_k127_7044601_1	1122179.KB890471_gene442	1.71e-102	348.0	COG3525@1|root,COG3525@2|Bacteria,4NGV2@976|Bacteroidetes,1IRPA@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20
TH3_k127_7044601_0	1121015.N789_02215	2.203e-107	360.0	COG0652@1|root,COG0652@2|Bacteria,1QCY4@1224|Proteobacteria,1RRUQ@1236|Gammaproteobacteria,1XCF4@135614|Xanthomonadales	135614|Xanthomonadales	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
TH3_k127_7044601_2	935948.KE386493_gene2375	1.899e-13	79.0	arCOG07336@1|root,2Z8ST@2|Bacteria,1TRXN@1239|Firmicutes,248NM@186801|Clostridia,42HXG@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7058634_62	94624.Bpet4290	2.801e-12	68.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VKHY@28216|Betaproteobacteria,3T90F@506|Alcaligenaceae	28216|Betaproteobacteria	LV	Retron-type reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
TH3_k127_7058634_68	1235803.C825_03137	1.646e-07	54.0	COG3547@1|root,COG3547@2|Bacteria,4PB8R@976|Bacteroidetes,2FYNJ@200643|Bacteroidia	976|Bacteroidetes	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7058634_58	1122919.KB905557_gene1198	3.243e-17	87.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,26QK1@186822|Paenibacillaceae	91061|Bacilli	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
TH3_k127_7058634_46	452637.Oter_2699	5.549e-37	145.0	COG4430@1|root,COG4430@2|Bacteria,46WQC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
TH3_k127_7058634_72	983544.Lacal_2171	0.0002344	52.0	COG3797@1|root,COG3797@2|Bacteria,4NSKS@976|Bacteroidetes,1I70K@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
TH3_k127_7058634_39	404589.Anae109_2915	6.706e-59	210.0	COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,43AHK@68525|delta/epsilon subdivisions,2X5XT@28221|Deltaproteobacteria,2YVZ8@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7058634_71	1121445.ATUZ01000020_gene2153	0.000111	51.0	COG2755@1|root,COG2755@2|Bacteria,1P2JM@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7058634_63	1151117.AJLF01000001_gene1466	3.862e-12	79.0	COG0463@1|root,arCOG00894@2157|Archaea,2XWXA@28890|Euryarchaeota,242RY@183968|Thermococci	183968|Thermococci	M	GtrA-like protein	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
TH3_k127_7058634_6	56780.SYN_02389	3.953e-162	531.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,42QEZ@68525|delta/epsilon subdivisions,2WKYB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TH3_k127_7058634_31	1123354.AUDR01000001_gene2018	1.655e-83	287.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VJ5G@28216|Betaproteobacteria,1KRK3@119069|Hydrogenophilales	1224|Proteobacteria	M	Glycosyl transferase family 2	arnC	GO:0000271,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0030258,GO:0030259,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
TH3_k127_7058634_11	1123354.AUDR01000001_gene2019	4.093e-145	468.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,1KTB7@119069|Hydrogenophilales	119069|Hydrogenophilales	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
TH3_k127_7058634_41	694440.JOMF01000004_gene1346	2.056e-48	186.0	COG0673@1|root,arCOG01622@2157|Archaea,2XTZY@28890|Euryarchaeota,2N9E7@224756|Methanomicrobia	224756|Methanomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.374	ko:K18855	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_7058634_53	469618.FVAG_00642	3.837e-23	103.0	COG3952@1|root,COG3952@2|Bacteria,37AN1@32066|Fusobacteria	32066|Fusobacteria	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
TH3_k127_7058634_37	1286106.MPL1_00887	8.811e-65	243.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TH3_k127_7058634_50	1217656.F964_03877	1.254e-24	114.0	COG2020@1|root,COG2020@2|Bacteria,1RJNV@1224|Proteobacteria,1SGB2@1236|Gammaproteobacteria,3NKGV@468|Moraxellaceae	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
TH3_k127_7058634_34	1403819.BATR01000112_gene3842	4.869e-74	258.0	COG0745@1|root,COG0745@2|Bacteria	1403819.BATR01000112_gene3842|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7058634_30	240016.ABIZ01000001_gene5833	8.277e-84	293.0	COG0642@1|root,COG2205@2|Bacteria,46V7H@74201|Verrucomicrobia	74201|Verrucomicrobia	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TH3_k127_7058634_12	1149133.ppKF707_4753	4.427e-130	441.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RYKY@1236|Gammaproteobacteria,1YFQD@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TH3_k127_7058634_66	1117108.PAALTS15_19168	2.146e-08	64.0	COG0726@1|root,COG3291@1|root,COG5184@1|root,COG5276@1|root,COG5434@1|root,COG0726@2|Bacteria,COG3291@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,COG5434@2|Bacteria,1UYD0@1239|Firmicutes,4HVHQ@91061|Bacilli,26U3Z@186822|Paenibacillaceae	91061|Bacilli	M	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,F5_F8_type_C
TH3_k127_7058634_2	497964.CfE428DRAFT_1569	4.222e-190	612.0	COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TH3_k127_7058634_29	240016.ABIZ01000001_gene5347	2.286e-85	295.0	COG1596@1|root,COG1596@2|Bacteria,46XCW@74201|Verrucomicrobia,2IVGU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
TH3_k127_7058634_25	1123070.KB899258_gene1891	9.653e-88	310.0	COG1596@1|root,COG1596@2|Bacteria,46ZHY@74201|Verrucomicrobia,2IUWB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
TH3_k127_7058634_42	240016.ABIZ01000001_gene5349	2.193e-44	184.0	COG1596@1|root,COG3206@1|root,COG1596@2|Bacteria,COG3206@2|Bacteria,46ZHY@74201|Verrucomicrobia,2IUWB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
TH3_k127_7058634_38	240016.ABIZ01000001_gene5350	4.079e-64	230.0	COG3267@1|root,COG3267@2|Bacteria,46XMZ@74201|Verrucomicrobia,2IW82@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
TH3_k127_7058634_33	1128421.JAGA01000003_gene2817	8.821e-75	259.0	COG0596@1|root,COG0596@2|Bacteria,2NQV9@2323|unclassified Bacteria	2|Bacteria	S	Alpha/beta hydrolase family	ybfF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0016790,GO:0044424,GO:0044444,GO:0044464,GO:0052689	-	ko:K01175	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
TH3_k127_7058634_32	1396141.BATP01000030_gene3705	8.348e-80	274.0	COG2197@1|root,COG2197@2|Bacteria,46V5W@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_7058634_21	1396141.BATP01000030_gene3706	5.15e-95	346.0	COG0642@1|root,COG4251@1|root,COG2205@2|Bacteria,COG4251@2|Bacteria,46UHX@74201|Verrucomicrobia,2IVRU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
TH3_k127_7058634_0	1254432.SCE1572_30430	9.351e-221	698.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2X250@28221|Deltaproteobacteria,2YXZE@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TH3_k127_7058634_23	497964.CfE428DRAFT_1931	4.672e-91	309.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TH3_k127_7058634_26	886293.Sinac_7025	2.241e-87	293.0	COG1225@1|root,COG1225@2|Bacteria,2IYHT@203682|Planctomycetes	203682|Planctomycetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TH3_k127_7058634_13	497964.CfE428DRAFT_1992	8.356e-130	425.0	COG3938@1|root,COG3938@2|Bacteria,46U8C@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Proline racemase	-	-	-	-	-	-	-	-	-	-	-	-	Pro_racemase
TH3_k127_7058634_8	497964.CfE428DRAFT_1990	2.482e-159	513.0	COG0665@1|root,COG0665@2|Bacteria,46TXP@74201|Verrucomicrobia	74201|Verrucomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
TH3_k127_7058634_70	1346791.M529_01465	3.319e-06	56.0	2CBBT@1|root,33166@2|Bacteria,1N354@1224|Proteobacteria,2USDI@28211|Alphaproteobacteria,2K9BJ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7058634_16	1123073.KB899242_gene1369	4.86e-120	394.0	COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria,1RRFC@1236|Gammaproteobacteria,1X4B2@135614|Xanthomonadales	135614|Xanthomonadales	EM	Belongs to the DapA family	dapA2	-	3.5.4.22	ko:K21062	ko00330,map00330	-	R02280	RC00679	ko00000,ko00001,ko01000	-	-	-	DHDPS
TH3_k127_7058634_57	194439.CT1729	6.69e-20	95.0	COG2189@1|root,COG2852@1|root,COG2189@2|Bacteria,COG2852@2|Bacteria,1FEW7@1090|Chlorobi	1090|Chlorobi	L	DNA methylase	-	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
TH3_k127_7058634_3	1210884.HG799465_gene11752	7.433e-188	602.0	COG1012@1|root,COG1012@2|Bacteria,2IYRE@203682|Planctomycetes	203682|Planctomycetes	C	ketoglutarate semialdehyde dehydrogenase	-	-	1.2.1.4	ko:K14519	ko00930,ko01100,ko01120,ko01220,map00930,map01100,map01120,map01220	-	R05099	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
TH3_k127_7058634_60	497964.CfE428DRAFT_0773	3.169e-14	75.0	2DBN7@1|root,2ZA2Y@2|Bacteria,46TTS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
TH3_k127_7058634_52	86416.Clopa_2098	3.722e-24	110.0	2A1FW@1|root,30PPA@2|Bacteria,1UA53@1239|Firmicutes,254CY@186801|Clostridia,36TYS@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7058634_20	497964.CfE428DRAFT_0773	2.577e-100	336.0	2DBN7@1|root,2ZA2Y@2|Bacteria,46TTS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
TH3_k127_7058634_1	886293.Sinac_5668	1.876e-219	688.0	COG2115@1|root,COG2115@2|Bacteria,2IWUS@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the xylose isomerase family	xylA	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
TH3_k127_7058634_7	1303518.CCALI_00532	1.748e-160	515.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
TH3_k127_7058634_69	553177.CAPSP0001_0648	1.308e-06	59.0	2F41P@1|root,33WTC@2|Bacteria,4PE72@976|Bacteroidetes,1IEPT@117743|Flavobacteriia,1EQRP@1016|Capnocytophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7058634_75	1121035.AUCH01000003_gene1396	0.0005261	46.0	2F41P@1|root,33WTC@2|Bacteria,1P4EC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7058634_67	497964.CfE428DRAFT_3353	4.992e-08	58.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,46SGF@74201|Verrucomicrobia	74201|Verrucomicrobia	H	UBA THIF-type NAD FAD binding protein	thiF	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
TH3_k127_7058634_10	977880.pRALTA_0046	2.929e-149	493.0	28IHG@1|root,2Z8IP@2|Bacteria,1R4RG@1224|Proteobacteria,2VVIT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7058634_45	1499967.BAYZ01000141_gene6156	2.366e-38	146.0	COG4634@1|root,COG4634@2|Bacteria,2NRUB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
TH3_k127_7058634_55	272123.Anacy_4446	3.153e-20	93.0	COG2442@1|root,COG2442@2|Bacteria,1G7T6@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
TH3_k127_7058634_56	1303518.CCALI_00532	4.572e-20	99.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
TH3_k127_7058634_73	278963.ATWD01000001_gene2663	0.0002416	44.0	COG2405@1|root,COG2405@2|Bacteria,3Y95W@57723|Acidobacteria,2JNS5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
TH3_k127_7058634_74	395961.Cyan7425_2060	0.0002688	44.0	COG2405@1|root,COG2405@2|Bacteria,1G6NZ@1117|Cyanobacteria,3KKNI@43988|Cyanothece	1117|Cyanobacteria	S	Domain of unknown function (DUF3368)	-	-	-	ko:K07066	-	-	-	-	ko00000	-	-	-	DUF3368
TH3_k127_7058634_64	69014.TK0917	4.552e-11	66.0	COG2886@1|root,arCOG00722@2157|Archaea,2Y0J3@28890|Euryarchaeota,244GE@183968|Thermococci	183968|Thermococci	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
TH3_k127_7058634_22	595460.RRSWK_05050	6.712e-92	312.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
TH3_k127_7058634_17	521674.Plim_1879	1.957e-113	385.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TH3_k127_7058634_36	1304872.JAGC01000003_gene2354	5.749e-67	248.0	COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,42TY0@68525|delta/epsilon subdivisions,2WQ74@28221|Deltaproteobacteria,2M9SS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
TH3_k127_7058634_15	1249627.D779_1354	1.082e-121	407.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,1S5ET@1236|Gammaproteobacteria,1WYQP@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
TH3_k127_7058634_14	1304872.JAGC01000003_gene2354	9.605e-128	428.0	COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,42TY0@68525|delta/epsilon subdivisions,2WQ74@28221|Deltaproteobacteria,2M9SS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
TH3_k127_7058634_47	1394178.AWOO02000018_gene6642	2.525e-36	154.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4EH55@85012|Streptosporangiales	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005509,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0120147,GO:1901564,GO:1903135,GO:1903136	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TH3_k127_7058634_48	998674.ATTE01000001_gene970	5.589e-34	142.0	COG1881@1|root,COG1881@2|Bacteria,1NQK5@1224|Proteobacteria,1S0T6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP,YHYH
TH3_k127_7058634_51	593750.Metfor_1047	1.656e-24	114.0	arCOG09580@1|root,arCOG09580@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7058634_27	593750.Metfor_1047	3.909e-87	304.0	arCOG09580@1|root,arCOG09580@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7058634_28	382464.ABSI01000007_gene4118	1.177e-86	291.0	COG0745@1|root,COG0745@2|Bacteria,46TFB@74201|Verrucomicrobia,2IUEX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TH3_k127_7058634_19	272134.KB731324_gene3229	5.359e-108	367.0	COG5002@1|root,COG5002@2|Bacteria,1GQDS@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TH3_k127_7058634_65	204669.Acid345_0203	1.284e-08	57.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,3Y3IF@57723|Acidobacteria,2JIPC@204432|Acidobacteriia	204432|Acidobacteriia	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
TH3_k127_7058634_5	1168034.FH5T_18125	4.823e-173	554.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_7058634_59	530564.Psta_3453	1.334e-14	76.0	COG1285@1|root,COG1285@2|Bacteria,2IZY6@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
TH3_k127_7058634_49	521674.Plim_3170	4.047e-30	125.0	COG1285@1|root,COG1285@2|Bacteria,2IZY6@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
TH3_k127_7058634_44	530564.Psta_3452	9.803e-41	160.0	COG5036@1|root,COG5036@2|Bacteria,2J00S@203682|Planctomycetes	203682|Planctomycetes	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
TH3_k127_7058634_4	1396141.BATP01000039_gene1469	1.072e-187	597.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH
TH3_k127_7058634_54	42256.RradSPS_0086	3.354e-22	104.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4CQK4@84995|Rubrobacteria	84995|Rubrobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
TH3_k127_7058634_40	1123508.JH636439_gene990	3.005e-54	196.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
TH3_k127_7058634_9	452637.Oter_1389	3.535e-155	533.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TH3_k127_7058634_35	861299.J421_5620	9.301e-70	246.0	28J3W@1|root,2Z900@2|Bacteria	2|Bacteria	S	NIPSNAP family containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
TH3_k127_7058634_24	448385.sce3153	3.265e-90	302.0	COG0670@1|root,COG0670@2|Bacteria,1R7VN@1224|Proteobacteria,43DVQ@68525|delta/epsilon subdivisions,2WZ04@28221|Deltaproteobacteria,2Z11K@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
TH3_k127_7058634_61	94122.Shewana3_0285	2.452e-12	69.0	COG0401@1|root,COG0401@2|Bacteria,1N7K3@1224|Proteobacteria,1SGD5@1236|Gammaproteobacteria,2QCT8@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Proteolipid membrane potential modulator	-	-	-	-	-	-	-	-	-	-	-	-	Pmp3
TH3_k127_7058634_18	278957.ABEA03000091_gene714	6.855e-111	365.0	COG0708@1|root,COG0708@2|Bacteria,46TGT@74201|Verrucomicrobia,3K7VW@414999|Opitutae	414999|Opitutae	L	exodeoxyribonuclease III	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
TH3_k127_7058634_43	1396418.BATQ01000078_gene592	7.966e-44	164.0	COG0620@1|root,COG0620@2|Bacteria,46W8R@74201|Verrucomicrobia,2IWM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cobalamin-independent synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
TH3_k127_7069165_8	273068.TTE0770	2.339e-78	271.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,42FCC@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
TH3_k127_7069165_5	1157490.EL26_23840	1.247e-100	346.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,4HC7I@91061|Bacilli,279D9@186823|Alicyclobacillaceae	91061|Bacilli	S	Protein of unknown function DUF111	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
TH3_k127_7069165_2	933262.AXAM01000001_gene380	7.679e-104	353.0	COG0318@1|root,COG0318@2|Bacteria,1NRID@1224|Proteobacteria,43CJB@68525|delta/epsilon subdivisions,2X7TP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
TH3_k127_7069165_18	1192034.CAP_6765	4.286e-05	49.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249	-	ko:K21781	ko00333,map00333	M00837,M00838	R06746	RC00039,RC01438	ko00000,ko00001,ko00002	-	-	-	PP-binding
TH3_k127_7069165_15	1116472.MGMO_20c00250	1.825e-21	108.0	COG1020@1|root,COG1020@2|Bacteria,1NK69@1224|Proteobacteria,1SKZR@1236|Gammaproteobacteria,1XFVG@135618|Methylococcales	135618|Methylococcales	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7069165_13	933262.AXAM01000001_gene381	7.757e-36	154.0	COG0644@1|root,COG0644@2|Bacteria,1QM8G@1224|Proteobacteria	1224|Proteobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
TH3_k127_7069165_3	338966.Ppro_0910	3.41e-103	354.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42QET@68525|delta/epsilon subdivisions,2WIZV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	AMP-binding enzyme	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
TH3_k127_7069165_9	1123008.KB905694_gene1758	6.929e-74	268.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,2FQIT@200643|Bacteroidia,22X2B@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DUF2062,Glycos_transf_2
TH3_k127_7069165_1	679935.Alfi_1534	6.594e-125	448.0	COG0204@1|root,COG2813@1|root,COG4258@1|root,COG0204@2|Bacteria,COG2813@2|Bacteria,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,2FQP4@200643|Bacteroidia	976|Bacteroidetes	I	Acyltransferase	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
TH3_k127_7069165_16	234267.Acid_6615	2.322e-17	94.0	28KX8@1|root,2ZAD8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7069165_0	886293.Sinac_6980	6.133e-150	489.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_7069165_10	761193.Runsl_4067	1.92e-67	239.0	COG1082@1|root,COG1082@2|Bacteria,4NFS5@976|Bacteroidetes,47NAA@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
TH3_k127_7069165_4	1158292.JPOE01000002_gene3555	6.001e-102	343.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
TH3_k127_7069165_11	1210884.HG799470_gene14506	1.474e-65	244.0	COG0584@1|root,COG0584@2|Bacteria,2J1MH@203682|Planctomycetes	203682|Planctomycetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
TH3_k127_7069165_7	1500281.JQKZ01000035_gene90	3.158e-84	292.0	COG4191@1|root,COG4191@2|Bacteria,4P85X@976|Bacteroidetes,1IJVC@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_3
TH3_k127_7069165_6	443143.GM18_4359	9.074e-92	317.0	COG0286@1|root,COG0286@2|Bacteria,1NTF8@1224|Proteobacteria	1224|Proteobacteria	L	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
TH3_k127_7069165_17	290317.Cpha266_1712	4.172e-17	88.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
TH3_k127_7069165_14	388413.ALPR1_07560	2.375e-22	110.0	2CCSR@1|root,32RWC@2|Bacteria,4NUMI@976|Bacteroidetes	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TH3_k127_7069165_12	443143.GM18_2872	4.354e-57	214.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,42N9K@68525|delta/epsilon subdivisions,2WINH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM N-6 DNA methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
TH3_k127_7110089_0	1123242.JH636434_gene5260	1.596e-270	857.0	COG4654@1|root,COG4654@2|Bacteria,2J54P@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
TH3_k127_7110089_1	1123242.JH636434_gene5259	1.579e-225	706.0	COG3119@1|root,COG3119@2|Bacteria,2IX9P@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TH3_k127_7110089_4	641524.ADICYQ_2511	3.096e-148	482.0	2DBQR@1|root,2ZAG2@2|Bacteria,4NK84@976|Bacteroidetes,47NS0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2
TH3_k127_7110089_2	1396418.BATQ01000117_gene4594	1.073e-212	670.0	2DBKQ@1|root,2Z9U7@2|Bacteria,46XD4@74201|Verrucomicrobia,2IVHS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7110089_10	1232437.KL662027_gene2817	1.762e-06	60.0	COG0607@1|root,COG0607@2|Bacteria,1N256@1224|Proteobacteria,42TIJ@68525|delta/epsilon subdivisions,2WQGJ@28221|Deltaproteobacteria,2MKF4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TH3_k127_7110089_9	794903.OPIT5_30270	1.142e-22	108.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	mauE	-	-	-	-	-	-	-	-	-	-	-	DoxX,MauE
TH3_k127_7110089_5	1254432.SCE1572_30435	2.594e-121	397.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,42S16@68525|delta/epsilon subdivisions,2WNEY@28221|Deltaproteobacteria,2YYRJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
TH3_k127_7110089_6	504472.Slin_1223	3.003e-109	362.0	COG2755@1|root,COG2755@2|Bacteria,4NIBN@976|Bacteroidetes,47NY7@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TH3_k127_7110089_3	472759.Nhal_2032	2.697e-159	516.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,1RPUI@1236|Gammaproteobacteria,1WXBQ@135613|Chromatiales	135613|Chromatiales	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
TH3_k127_7110089_8	452637.Oter_1883	3.984e-28	121.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TH3_k127_7110089_7	926550.CLDAP_25650	2.417e-49	182.0	COG2267@1|root,COG2267@2|Bacteria,2G6DZ@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TH3_k127_7117416_5	497964.CfE428DRAFT_2773	2.083e-53	205.0	2F6K4@1|root,33Z30@2|Bacteria,46VYC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative beta-barrel porin 2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
TH3_k127_7117416_6	497964.CfE428DRAFT_2774	1.276e-49	186.0	COG1596@1|root,COG1596@2|Bacteria,46VQY@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
TH3_k127_7117416_3	497964.CfE428DRAFT_2775	1.423e-149	499.0	COG0489@1|root,COG0489@2|Bacteria,46UJ7@74201|Verrucomicrobia	74201|Verrucomicrobia	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
TH3_k127_7117416_7	497964.CfE428DRAFT_3096	9.217e-44	166.0	COG0250@1|root,COG0250@2|Bacteria,46SYX@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcription termination factor nusG	-	-	-	ko:K05785	-	-	-	-	ko00000,ko03000	-	-	-	NusG
TH3_k127_7117416_4	583355.Caka_1995	9.525e-98	338.0	COG0472@1|root,COG0472@2|Bacteria,46SNJ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
TH3_k127_7117416_1	573413.Spirs_4003	1.457e-191	620.0	COG0188@1|root,COG0188@2|Bacteria,2J5Y9@203691|Spirochaetes	203691|Spirochaetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
TH3_k127_7117416_9	1121447.JONL01000003_gene3289	8.548e-11	72.0	COG0457@1|root,COG0457@2|Bacteria,1NNP4@1224|Proteobacteria,42VPE@68525|delta/epsilon subdivisions,2WRZ3@28221|Deltaproteobacteria,2MBFM@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
TH3_k127_7117416_0	886293.Sinac_7042	9.459e-319	1009.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IX73@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PBS lyase HEAT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
TH3_k127_7117416_8	639030.JHVA01000001_gene3130	2.198e-12	74.0	2BIJA@1|root,32CS2@2|Bacteria,3Y9DG@57723|Acidobacteria	57723|Acidobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
TH3_k127_7117416_2	452637.Oter_0679	3.012e-151	490.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,3K7KM@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
TH3_k127_7145864_8	278957.ABEA03000019_gene1865	4.364e-32	133.0	2DRPS@1|root,33CHR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
TH3_k127_7145864_6	497964.CfE428DRAFT_0259	8.043e-59	209.0	COG2151@1|root,COG2151@2|Bacteria,46SWX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
TH3_k127_7145864_11	240016.ABIZ01000001_gene2614	1.346e-06	63.0	COG2373@1|root,COG2885@1|root,COG3210@1|root,COG5563@1|root,COG2373@2|Bacteria,COG2885@2|Bacteria,COG3210@2|Bacteria,COG5563@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	3.1.4.3	ko:K01114,ko:K12287,ko:K15125,ko:K16191,ko:K20276	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,ko05133,map00562,map00564,map00565,map01100,map01110,map02024,map04919,map05133	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko00536,ko01000,ko02000,ko02042,ko02044	1.B.6.1.3	-	-	DUF1573,OmpA
TH3_k127_7145864_3	1121904.ARBP01000023_gene4986	2.97e-105	389.0	COG3210@1|root,COG4886@1|root,COG4935@1|root,COG3210@2|Bacteria,COG4886@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K15125,ko:K20276	ko02024,ko05133,map02024,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	CHU_C,Flg_new,Glug,LRR_5,PKD,P_proprotein,SprB
TH3_k127_7145864_10	1116472.MGMO_57c00180	1.069e-09	74.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,1R1H9@1224|Proteobacteria,1T52V@1236|Gammaproteobacteria,1XEUH@135618|Methylococcales	135618|Methylococcales	EH	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD,fn3
TH3_k127_7145864_4	429009.Adeg_0968	4.158e-91	319.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,42F3J@68295|Thermoanaerobacterales	186801|Clostridia	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
TH3_k127_7145864_2	639282.DEFDS_0642	3.893e-123	411.0	COG0318@1|root,COG0318@2|Bacteria,2GETC@200930|Deferribacteres	200930|Deferribacteres	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
TH3_k127_7145864_9	1131266.ARWQ01000091_gene18	5.691e-10	63.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7145864_1	497964.CfE428DRAFT_2462	3.82e-145	469.0	COG0105@1|root,COG0105@2|Bacteria,46T8K@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Nucleoside diphosphate kinase	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
TH3_k127_7145864_7	671143.DAMO_2861	9.495e-34	138.0	COG0494@1|root,COG0494@2|Bacteria,2NPUY@2323|unclassified Bacteria	2|Bacteria	L	NUDIX domain	mutY	-	3.6.1.55	ko:K03574,ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,NUDIX,NUDIX_4
TH3_k127_7145864_0	481448.Minf_0010	5.058e-184	584.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,37GBP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TH3_k127_7145864_12	481448.Minf_2089	6.539e-06	57.0	COG1729@1|root,COG1729@2|Bacteria,46ZG7@74201|Verrucomicrobia,37H0Y@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
TH3_k127_7145864_5	478741.JAFS01000001_gene2106	2.15e-65	228.0	COG0498@1|root,COG0498@2|Bacteria,46TYU@74201|Verrucomicrobia,37G8J@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TH3_k127_7180474_5	661478.OP10G_2091	5.258e-115	383.0	COG4030@1|root,COG4030@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
TH3_k127_7180474_3	1150600.ADIARSV_4037	9.637e-132	433.0	28HII@1|root,2Z7TZ@2|Bacteria,4NHR6@976|Bacteroidetes,1INR1@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7180474_2	243090.RB10165	1.356e-152	514.0	COG1305@1|root,COG3509@1|root,COG1305@2|Bacteria,COG3509@2|Bacteria,2IX6R@203682|Planctomycetes	203682|Planctomycetes	Q	depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,DLH,Transglut_core
TH3_k127_7180474_7	530564.Psta_0399	1.107e-83	287.0	COG3970@1|root,COG3970@2|Bacteria,2IWUC@203682|Planctomycetes	203682|Planctomycetes	S	fumarylacetoacetate (FAA) hydrolase	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
TH3_k127_7180474_0	1121346.KB899817_gene3149	2.563e-295	920.0	COG0129@1|root,COG0129@2|Bacteria,1U56J@1239|Firmicutes,4HD31@91061|Bacilli,26U7U@186822|Paenibacillaceae	91061|Bacilli	EG	Belongs to the IlvD Edd family	-	-	4.2.1.82	ko:K22396	ko00040,map00040	-	R02429	RC00543	ko00000,ko00001,ko01000	-	-	-	ILVD_EDD
TH3_k127_7180474_1	861299.J421_1753	1.49e-280	904.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
TH3_k127_7180474_4	504472.Slin_3038	3.581e-116	393.0	COG4636@1|root,COG4636@2|Bacteria,4NFKR@976|Bacteroidetes,47K44@768503|Cytophagia	976|Bacteroidetes	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TH3_k127_7180474_10	661478.OP10G_2992	1.563e-11	74.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_7180474_9	1303518.CCALI_00933	3.683e-15	88.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_7180474_8	1121289.JHVL01000023_gene71	6.901e-45	174.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,36EIP@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
TH3_k127_7180474_11	297246.lpp1558	1.981e-08	60.0	COG2801@1|root,COG2801@2|Bacteria,1MWVQ@1224|Proteobacteria,1RN12@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_29,rve
TH3_k127_7180474_6	1321778.HMPREF1982_00675	8.465e-111	372.0	COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,24808@186801|Clostridia,26AG8@186813|unclassified Clostridiales	186801|Clostridia	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	-	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
TH3_k127_718084_0	452637.Oter_3827	1.5e-184	582.0	COG0057@1|root,COG0057@2|Bacteria,46S59@74201|Verrucomicrobia,3K77U@414999|Opitutae	414999|Opitutae	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
TH3_k127_718084_1	926569.ANT_29620	8.249e-130	428.0	COG1180@1|root,COG1180@2|Bacteria,2G6B2@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
TH3_k127_718084_3	765912.Thimo_3050	1.059e-94	319.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1WX63@135613|Chromatiales	135613|Chromatiales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
TH3_k127_718084_5	504728.K649_06595	2.1e-61	225.0	COG3257@1|root,COG3257@2|Bacteria,1WJWA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	protein possibly involved in glyoxylate utilization	-	-	3.5.3.26	ko:K14977	ko00230,ko01120,map00230,map01120	-	R05554	RC01419	ko00000,ko00001,ko01000	-	-	-	Cupin_2
TH3_k127_718084_2	391625.PPSIR1_08312	2.929e-129	436.0	COG5434@1|root,COG5434@2|Bacteria,1RJPM@1224|Proteobacteria,42T21@68525|delta/epsilon subdivisions,2WPCS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TH3_k127_718084_7	1396141.BATP01000045_gene1848	1.208e-08	68.0	COG2911@1|root,COG3866@1|root,COG4932@1|root,COG5267@1|root,COG2911@2|Bacteria,COG3866@2|Bacteria,COG4932@2|Bacteria,COG5267@2|Bacteria,46TJE@74201|Verrucomicrobia,2IVHT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
TH3_k127_718084_4	314230.DSM3645_10162	1.089e-87	299.0	COG0524@1|root,COG0524@2|Bacteria,2IXGC@203682|Planctomycetes	203682|Planctomycetes	H	PFAM PfkB	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
TH3_k127_718084_6	1121456.ATVA01000014_gene568	4.996e-45	175.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2M9FY@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
TH3_k127_7198353_14	740709.A10D4_00975	1.54e-19	101.0	COG1520@1|root,COG3209@1|root,COG3210@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	yeeJ	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Calx-beta,Flg_new,HYR,Laminin_G_3,PQQ_2
TH3_k127_7198353_16	584708.Apau_2407	4.625e-06	57.0	COG5492@1|root,COG5492@2|Bacteria,3TCF8@508458|Synergistetes	508458|Synergistetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7198353_4	1121957.ATVL01000014_gene1459	4.995e-111	379.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7198353_7	1168034.FH5T_01595	1.222e-81	289.0	COG1520@1|root,COG1520@2|Bacteria,4P28I@976|Bacteroidetes,2FX0J@200643|Bacteroidia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_7198353_5	673860.AciM339_1573	2.256e-91	314.0	COG0182@1|root,arCOG01123@2157|Archaea,2Y86P@28890|Euryarchaeota,3F36H@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	-	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K03239,ko:K08963	ko00270,ko01100,ko03013,map00270,map01100,map03013	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000,ko03012	-	-	-	IF-2B
TH3_k127_7198353_1	880072.Desac_1581	3.459e-203	645.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2MR7G@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
TH3_k127_7198353_6	264732.Moth_0141	5.734e-84	291.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,42F66@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
TH3_k127_7198353_10	583355.Caka_1868	7.605e-41	155.0	COG0695@1|root,COG0695@2|Bacteria,46SXS@74201|Verrucomicrobia,3K871@414999|Opitutae	414999|Opitutae	O	Glutaredoxin	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
TH3_k127_7198353_8	1123073.KB899245_gene180	3.219e-69	250.0	COG1929@1|root,COG1929@2|Bacteria,1MVG9@1224|Proteobacteria,1RMC6@1236|Gammaproteobacteria,1X595@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
TH3_k127_7198353_11	481448.Minf_1629	2.513e-39	157.0	COG0491@1|root,COG0491@2|Bacteria,46S7X@74201|Verrucomicrobia,37GB4@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TH3_k127_7198353_17	1312959.KI914674_gene3398	4.668e-05	58.0	COG3087@1|root,COG3291@1|root,COG3087@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Laminin_G_3,PKD
TH3_k127_7198353_15	1408473.JHXO01000006_gene1129	2.1e-13	86.0	COG3211@1|root,COG4935@1|root,COG3211@2|Bacteria,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,2G16U@200643|Bacteroidia	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
TH3_k127_7198353_0	1396141.BATP01000006_gene5432	2.473e-243	819.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
TH3_k127_7198353_9	1156937.MFUM_290037	3.396e-65	226.0	COG0440@1|root,COG0440@2|Bacteria,46SUP@74201|Verrucomicrobia,37GJ7@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	ACT domain	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
TH3_k127_7198353_2	452637.Oter_3478	4.096e-196	616.0	COG0059@1|root,COG0059@2|Bacteria,46SI2@74201|Verrucomicrobia,3K7PK@414999|Opitutae	74201|Verrucomicrobia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
TH3_k127_7198353_12	440512.C211_12597	9.137e-39	166.0	COG1450@1|root,COG3147@1|root,COG1450@2|Bacteria,COG3147@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	General Secretion Pathway protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	SPOR,Secretin,Secretin_N
TH3_k127_7198353_3	595460.RRSWK_04184	1.42e-149	493.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
TH3_k127_7205470_10	1034345.CAEM01000007_gene1354	1.254e-16	89.0	COG0454@1|root,COG0533@1|root,COG0456@2|Bacteria,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CUKY@84998|Coriobacteriia	84998|Coriobacteriia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
TH3_k127_7205470_8	1042156.CXIVA_02020	1.242e-25	111.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,36IUF@31979|Clostridiaceae	186801|Clostridia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
TH3_k127_7205470_6	497964.CfE428DRAFT_3691	6.918e-77	268.0	COG0611@1|root,COG0611@2|Bacteria,46SV7@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
TH3_k127_7205470_11	1123070.KB899249_gene301	4.115e-11	72.0	COG1266@1|root,COG1266@2|Bacteria,46T6D@74201|Verrucomicrobia,2IUVK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
TH3_k127_7205470_0	517418.Ctha_1399	2.469e-199	647.0	COG1331@1|root,COG1331@2|Bacteria,1FDQN@1090|Chlorobi	1090|Chlorobi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
TH3_k127_7205470_1	886293.Sinac_4798	2.889e-119	398.0	COG0577@1|root,COG0577@2|Bacteria,2IX11@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TH3_k127_7205470_4	530564.Psta_4732	1.498e-83	286.0	COG1136@1|root,COG1136@2|Bacteria,2IY81@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_7205470_5	1232437.KL662020_gene700	7.258e-80	290.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42PAC@68525|delta/epsilon subdivisions,2WKAD@28221|Deltaproteobacteria,2MMGU@213118|Desulfobacterales	28221|Deltaproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TH3_k127_7205470_7	1167006.UWK_02169	3.628e-52	206.0	COG1538@1|root,COG1538@2|Bacteria,1NQXF@1224|Proteobacteria,42ZDW@68525|delta/epsilon subdivisions,2WTVP@28221|Deltaproteobacteria,2MMSE@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TH3_k127_7205470_2	1396418.BATQ01000113_gene4631	1.168e-118	392.0	COG1723@1|root,COG1723@2|Bacteria	2|Bacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	yagE	-	-	-	-	-	-	-	-	-	-	-	DUF155
TH3_k127_7205470_3	886293.Sinac_7584	8.599e-113	376.0	COG0715@1|root,COG0715@2|Bacteria,2IX2Y@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
TH3_k127_7205470_12	583355.Caka_2909	1.72e-09	60.0	COG4974@1|root,COG4974@2|Bacteria,46UB9@74201|Verrucomicrobia,3K9DD@414999|Opitutae	414999|Opitutae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
TH3_k127_7205470_9	945713.IALB_1410	8.292e-18	85.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
TH3_k127_7212215_14	1237500.ANBA01000014_gene5634	2.71e-12	74.0	COG5433@1|root,COG5433@2|Bacteria,2HYBN@201174|Actinobacteria	201174|Actinobacteria	L	required for the transposition of insertion element IS2404	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
TH3_k127_7212215_9	380394.Lferr_0309	1.312e-64	242.0	COG5433@1|root,COG5433@2|Bacteria,1RAHU@1224|Proteobacteria,1S1TZ@1236|Gammaproteobacteria,2NDWK@225057|Acidithiobacillales	1236|Gammaproteobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc,DUF4338
TH3_k127_7212215_12	278957.ABEA03000091_gene684	1.516e-43	164.0	COG0499@1|root,COG0499@2|Bacteria,46SGX@74201|Verrucomicrobia,3K76U@414999|Opitutae	414999|Opitutae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
TH3_k127_7212215_8	1469607.KK073768_gene3614	2.042e-82	282.0	COG3293@1|root,COG3293@2|Bacteria,1G0BW@1117|Cyanobacteria,1HNSC@1161|Nostocales	1117|Cyanobacteria	L	transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
TH3_k127_7212215_16	1463825.JNXC01000053_gene31	1.451e-05	55.0	COG3507@1|root,COG3507@2|Bacteria,2I911@201174|Actinobacteria,4E0PM@85010|Pseudonocardiales	201174|Actinobacteria	G	Cellulose Binding Domain Type IV	-	-	3.2.1.55	ko:K15921	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43	-	CBM_4_9,CBM_6,Glyco_hydro_43
TH3_k127_7212215_4	1396141.BATP01000060_gene4560	2.539e-132	446.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
TH3_k127_7212215_13	111781.Lepto7376_3756	7.031e-27	126.0	COG1572@1|root,COG3209@1|root,COG3210@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CARDB,RHS_repeat
TH3_k127_7212215_7	497964.CfE428DRAFT_6357	2.006e-84	286.0	COG3176@1|root,COG3176@2|Bacteria,46UGN@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
TH3_k127_7212215_11	880070.Cycma_1815	1.218e-52	192.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,AhpC-TSA_2
TH3_k127_7212215_15	948106.AWZT01000019_gene3975	3.641e-08	59.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2VXXB@28216|Betaproteobacteria,1K9C3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
TH3_k127_7212215_17	1387312.BAUS01000002_gene286	3.742e-05	53.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2W81G@28216|Betaproteobacteria,2KNB0@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
TH3_k127_7212215_10	497964.CfE428DRAFT_5990	1.136e-60	218.0	COG1595@1|root,COG1595@2|Bacteria,46W20@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_7212215_6	716544.wcw_0442	1.225e-125	409.0	COG1028@1|root,COG1028@2|Bacteria,2JG7F@204428|Chlamydiae	204428|Chlamydiae	IQ	KR domain	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
TH3_k127_7212215_2	1496688.ER33_11555	4.723e-250	789.0	COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria,22THV@167375|Cyanobium	1117|Cyanobacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
TH3_k127_7212215_0	1454004.AW11_02080	0.0	1355.0	COG0166@1|root,COG0166@2|Bacteria,1PQU4@1224|Proteobacteria,2VKX3@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the GPI family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7212215_5	1121920.AUAU01000005_gene1032	2.122e-129	422.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,3Y4JU@57723|Acidobacteria	57723|Acidobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
TH3_k127_7212215_3	641491.DND132_2614	1.333e-152	496.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TH3_k127_7212215_1	876044.IMCC3088_2538	1.287e-252	792.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1RYI9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
TH3_k127_7235873_7	1121859.KB890750_gene148	0.0003561	48.0	COG3064@1|root,COG3064@2|Bacteria,4NR0W@976|Bacteroidetes	976|Bacteroidetes	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,PG_binding_1
TH3_k127_7235873_6	240016.ABIZ01000001_gene5673	2.338e-07	61.0	COG3209@1|root,COG3209@2|Bacteria,46VWR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39,RHS_repeat
TH3_k127_7235873_5	945543.VIBR0546_02675	2.17e-07	62.0	COG3209@1|root,COG3209@2|Bacteria,1PDT2@1224|Proteobacteria,1TEF8@1236|Gammaproteobacteria,1XZDG@135623|Vibrionales	135623|Vibrionales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7235873_3	240016.ABIZ01000001_gene5629	4.253e-43	166.0	COG2912@1|root,COG2912@2|Bacteria	2|Bacteria	P	Transglutaminase-like superfamily	CP_0628	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2,VIT
TH3_k127_7235873_0	526218.Sterm_4083	3.546e-103	350.0	COG5505@1|root,COG5505@2|Bacteria,37B8T@32066|Fusobacteria	32066|Fusobacteria	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
TH3_k127_7235873_1	443143.GM18_3718	2.066e-93	316.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,43TH3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
TH3_k127_7235873_2	497964.CfE428DRAFT_1669	5.111e-69	241.0	COG0563@1|root,COG0563@2|Bacteria,46SW4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
TH3_k127_7235873_4	452637.Oter_1047	6.925e-41	163.0	COG0583@1|root,COG0583@2|Bacteria,46V82@74201|Verrucomicrobia,3K8TT@414999|Opitutae	414999|Opitutae	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TH3_k127_7235968_0	497964.CfE428DRAFT_3817	3.54e-185	589.0	COG1690@1|root,COG1690@2|Bacteria,46SU0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA-splicing ligase RtcB	-	-	-	-	-	-	-	-	-	-	-	-	RtcB
TH3_k127_7235968_3	497964.CfE428DRAFT_2414	9.154e-98	335.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
TH3_k127_7235968_1	344747.PM8797T_22613	3.547e-152	491.0	COG4639@1|root,COG4639@2|Bacteria,2IZ4C@203682|Planctomycetes	203682|Planctomycetes	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,HD
TH3_k127_7235968_2	1396418.BATQ01000161_gene5597	3.815e-119	389.0	COG1423@1|root,COG1423@2|Bacteria	2|Bacteria	L	RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	RNA_ligase
TH3_k127_7235968_4	240016.ABIZ01000001_gene428	1.182e-71	246.0	COG1403@1|root,COG1403@2|Bacteria,46UDR@74201|Verrucomicrobia,2IUK8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_4
TH3_k127_7235968_5	267608.RSp0206	4.284e-11	64.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2VI1H@28216|Betaproteobacteria,1K3UX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
TH3_k127_7305091_4	1211777.BN77_p2190020	1.181e-117	389.0	COG0451@1|root,COG0451@2|Bacteria,1MW3K@1224|Proteobacteria,2TTTJ@28211|Alphaproteobacteria,4BCIX@82115|Rhizobiaceae	28211|Alphaproteobacteria	GM	NAD(P)H-binding	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
TH3_k127_7305091_8	269799.Gmet_2367	8.577e-80	288.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
TH3_k127_7305091_2	1123242.JH636434_gene3280	4.109e-158	511.0	COG0823@1|root,COG0823@2|Bacteria,2IYQ1@203682|Planctomycetes	203682|Planctomycetes	U	Protein of unknown function (DUF3748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3748,PD40
TH3_k127_7305091_3	497964.CfE428DRAFT_2490	1.976e-157	518.0	COG0497@1|root,COG0497@2|Bacteria,46SGB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
TH3_k127_7305091_7	497964.CfE428DRAFT_2489	4.908e-83	283.0	COG1235@1|root,COG1235@2|Bacteria,46SRW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Beta-lactamase superfamily domain	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
TH3_k127_7305091_9	497964.CfE428DRAFT_2488	4.808e-79	285.0	COG0457@1|root,COG0457@2|Bacteria,46SRS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7305091_1	497964.CfE428DRAFT_6291	2.707e-169	544.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Copper-bind,Cytochrom_C,Laminin_G_3
TH3_k127_7305091_10	481448.Minf_2259	2.539e-78	270.0	COG0084@1|root,COG0084@2|Bacteria,46SKF@74201|Verrucomicrobia,37GKS@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
TH3_k127_7305091_12	1268237.G114_09454	7.207e-25	108.0	2EGMM@1|root,33ADT@2|Bacteria,1R0Q0@1224|Proteobacteria,1T4N8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_4
TH3_k127_7305091_11	192952.MM_3371	2.368e-56	211.0	arCOG06820@1|root,arCOG06820@2157|Archaea,2XVYD@28890|Euryarchaeota,2N917@224756|Methanomicrobia	224756|Methanomicrobia	S	YoaP-like	-	-	-	-	-	-	-	-	-	-	-	-	YoaP
TH3_k127_7305091_0	886293.Sinac_0736	1.589e-190	628.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2IYAH@203682|Planctomycetes	203682|Planctomycetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
TH3_k127_7305091_5	1185876.BN8_06038	2.14e-105	352.0	COG1082@1|root,COG1082@2|Bacteria,4NGKX@976|Bacteroidetes,47JP9@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_7305091_6	240016.ABIZ01000001_gene1588	6.264e-89	308.0	COG0673@1|root,COG0673@2|Bacteria,46TM9@74201|Verrucomicrobia,2ITZ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_7305091_14	395495.Lcho_0773	4.098e-05	46.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,2VHUB@28216|Betaproteobacteria,1KPAP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
TH3_k127_7325326_11	411479.BACUNI_04071	3.605e-112	383.0	COG0383@1|root,COG0383@2|Bacteria,4NI6N@976|Bacteroidetes,2FQGF@200643|Bacteroidia,4ANYA@815|Bacteroidaceae	976|Bacteroidetes	G	COG COG0383 Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
TH3_k127_7325326_0	1121106.JQKB01000056_gene5861	0.0	1147.0	COG1413@1|root,COG1413@2|Bacteria,1R5Z1@1224|Proteobacteria	1224|Proteobacteria	C	lyase activity	capB	-	-	ko:K01932	-	-	-	-	ko00000,ko01000	-	-	-	-
TH3_k127_7325326_29	1192034.CAP_6422	7e-13	79.0	2E205@1|root,32X8D@2|Bacteria,1N4MZ@1224|Proteobacteria,43CVC@68525|delta/epsilon subdivisions,2X83A@28221|Deltaproteobacteria,2YW05@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7325326_4	1121106.JQKB01000056_gene5865	2.406e-180	604.0	28MUA@1|root,2ZB28@2|Bacteria,1R8RF@1224|Proteobacteria	1224|Proteobacteria	S	Capsule biosynthesis CapC	-	-	-	ko:K22116	-	-	-	-	ko00000	-	-	-	Caps_synth_CapC
TH3_k127_7325326_27	1906.SFRA_03940	8.283e-14	85.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	kdpE	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TH3_k127_7325326_38	1033744.CAEL01000023_gene258	0.0007059	53.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,22H03@1570339|Peptoniphilaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
TH3_k127_7325326_36	1122599.AUGR01000027_gene1284	5.899e-05	57.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RYEM@1236|Gammaproteobacteria,1XHAK@135619|Oceanospirillales	135619|Oceanospirillales	T	CHASE2	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,EAL,GGDEF
TH3_k127_7325326_26	96561.Dole_0867	6.194e-14	77.0	COG2204@1|root,COG3829@1|root,COG4191@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM1A@28221|Deltaproteobacteria,2MJZM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
TH3_k127_7325326_30	1122201.AUAZ01000018_gene1698	1.096e-10	69.0	2E5B0@1|root,33033@2|Bacteria,1ND0X@1224|Proteobacteria,1SEBX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7325326_15	261292.Nit79A3_3402	1.134e-63	225.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VQN2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
TH3_k127_7325326_25	351160.RCIX1317	9.243e-16	79.0	COG0286@1|root,arCOG02632@2157|Archaea,2XVXC@28890|Euryarchaeota,2N9DJ@224756|Methanomicrobia	224756|Methanomicrobia	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
TH3_k127_7325326_6	1499967.BAYZ01000177_gene5729	1.452e-145	464.0	COG0207@1|root,COG0207@2|Bacteria	2|Bacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
TH3_k127_7325326_9	547042.BACCOPRO_00992	4.035e-122	420.0	COG1572@1|root,COG1572@2|Bacteria,4PJMZ@976|Bacteroidetes,2FZ9J@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
TH3_k127_7325326_22	1123242.JH636435_gene1168	3.952e-25	113.0	COG1413@1|root,COG1413@2|Bacteria,2J2I0@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_7325326_18	1168034.FH5T_19355	3.787e-47	183.0	COG1387@1|root,COG1387@2|Bacteria,4NMBC@976|Bacteroidetes,2FNU7@200643|Bacteroidia	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_7325326_16	88036.EFJ24329	6.318e-57	206.0	COG0637@1|root,KOG2177@1|root,KOG2177@2759|Eukaryota,KOG2914@2759|Eukaryota,37MAK@33090|Viridiplantae,3GD1A@35493|Streptophyta	35493|Streptophyta	O	NHL repeat-containing protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009416,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0010196,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:1990066	-	-	-	-	-	-	-	-	-	-	HAD_2,NHL,Thioredoxin_8
TH3_k127_7325326_33	608538.HTH_0820	6.1e-08	58.0	COG0268@1|root,COG0268@2|Bacteria,2G49M@200783|Aquificae	200783|Aquificae	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
TH3_k127_7325326_35	452637.Oter_0873	6.772e-06	52.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
TH3_k127_7325326_24	497964.CfE428DRAFT_6371	5.824e-17	83.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015684,GO:0030001,GO:0033554,GO:0034220,GO:0034755,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070627,GO:0070838,GO:0072511,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098707,GO:0098711,GO:0098739,GO:0099587,GO:1903874	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
TH3_k127_7325326_2	452637.Oter_0871	1.458e-203	658.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia,3K85F@414999|Opitutae	414999|Opitutae	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
TH3_k127_7325326_14	497964.CfE428DRAFT_5731	7.579e-64	225.0	COG2197@1|root,COG2197@2|Bacteria,46UBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_7325326_5	378806.STAUR_7504	8.785e-161	544.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,1QUYA@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TH3_k127_7325326_23	378806.STAUR_1759	1.777e-19	104.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria	1224|Proteobacteria	G	Domain of unknown function (DUF4982)	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
TH3_k127_7325326_28	886293.Sinac_6222	8.787e-14	81.0	COG2165@1|root,COG2165@2|Bacteria,2J4VP@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_7325326_19	1121447.JONL01000003_gene3115	1.874e-39	158.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,42SCB@68525|delta/epsilon subdivisions,2WPEA@28221|Deltaproteobacteria,2MBDI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	hydrolase, HAD-superfamily, subfamily IIIA	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
TH3_k127_7325326_3	886293.Sinac_6373	9.263e-198	634.0	COG0449@1|root,COG0449@2|Bacteria,2IXF9@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
TH3_k127_7325326_12	240016.ABIZ01000001_gene1539	9.821e-84	291.0	COG1520@1|root,COG1520@2|Bacteria,46TV4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_7325326_7	530564.Psta_2735	4.695e-140	458.0	COG1520@1|root,COG1520@2|Bacteria,2IYI8@203682|Planctomycetes	203682|Planctomycetes	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_7325326_34	382464.ABSI01000010_gene3259	8.053e-08	63.0	COG4675@1|root,COG4675@2|Bacteria	2|Bacteria	M	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Collar,DUF859
TH3_k127_7325326_32	1120963.KB894499_gene421	3.378e-08	68.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.4.21.96	ko:K01361,ko:K13277,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Amidase_2,Big_2,CBM_X2,DUF1983,DUF2961,Glucosaminidase,LRR_5,Laminin_G_3,PA,Peptidase_S8,Phage-tail_3,SLH,fn3_5
TH3_k127_7325326_37	430498.S8BTV9	0.0004607	52.0	28PJD@1|root,2QW7I@2759|Eukaryota,39TJA@33154|Opisthokonta,3NWYV@4751|Fungi,3QM7J@4890|Ascomycota	4751|Fungi	G	Pectinolytic enzyme consist of four classes of enzymes pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity)	plyC	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7325326_1	497964.CfE428DRAFT_1614	7.627e-295	947.0	COG1197@1|root,COG1197@2|Bacteria,46S6Y@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
TH3_k127_7325326_21	1123508.JH636439_gene1132	2.715e-35	153.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
TH3_k127_7325326_17	748449.Halha_1319	1.536e-56	209.0	COG3940@1|root,COG3940@2|Bacteria,1UJSY@1239|Firmicutes,25F9C@186801|Clostridia,3WB0P@53433|Halanaerobiales	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
TH3_k127_7325326_10	1396418.BATQ01000133_gene3999	5.374e-120	399.0	COG0624@1|root,COG0624@2|Bacteria,46VZE@74201|Verrucomicrobia,2IW3Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
TH3_k127_7325326_20	497964.CfE428DRAFT_6409	1.499e-37	157.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
TH3_k127_7325326_31	349741.Amuc_0983	6.747e-10	63.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2,RHS_repeat
TH3_k127_7346471_2	794903.OPIT5_29635	2.271e-180	579.0	COG2152@1|root,COG2152@2|Bacteria,46S8T@74201|Verrucomicrobia,3K7JP@414999|Opitutae	414999|Opitutae	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
TH3_k127_7346471_7	929562.Emtol_2733	5.433e-22	110.0	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes,47X99@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
TH3_k127_7346471_1	1278073.MYSTI_03564	5.432e-226	743.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WJ2A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TH3_k127_7346471_8	194439.CT1119	6.608e-05	51.0	COG3449@1|root,COG3449@2|Bacteria,1FEK2@1090|Chlorobi	1090|Chlorobi	L	SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
TH3_k127_7346471_3	1158292.JPOE01000002_gene3555	1.578e-56	200.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
TH3_k127_7346471_6	497964.CfE428DRAFT_4858	8.954e-33	132.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
TH3_k127_7346471_0	1267535.KB906767_gene3736	0.0	1061.0	COG0438@1|root,COG0438@2|Bacteria,3Y68X@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TH3_k127_7346471_4	1307759.JOMJ01000004_gene2828	6.677e-50	183.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,42QRD@68525|delta/epsilon subdivisions,2WMYW@28221|Deltaproteobacteria,2MC9C@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
TH3_k127_73585_28	497964.CfE428DRAFT_4864	2.073e-66	237.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_73585_14	234267.Acid_2658	5.406e-134	439.0	COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	BNR_2
TH3_k127_73585_11	1453501.JELR01000001_gene2132	4.057e-146	485.0	COG1409@1|root,COG1409@2|Bacteria,1NS3S@1224|Proteobacteria,1RR8K@1236|Gammaproteobacteria,466XF@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
TH3_k127_73585_49	1121272.KB903251_gene659	0.000541	51.0	COG3866@1|root,COG4733@1|root,COG3866@2|Bacteria,COG4733@2|Bacteria,2GNKW@201174|Actinobacteria,4DAGW@85008|Micromonosporales	201174|Actinobacteria	G	Amb_all	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	DUF1080,Pec_lyase_C
TH3_k127_73585_2	1267535.KB906767_gene2459	4.389e-247	784.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23,3.2.1.4	ko:K01179,ko:K01190,ko:K12308	ko00052,ko00500,ko00511,ko00600,ko01100,map00052,map00500,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114,R06200,R11307,R11308	RC00049,RC00452	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,DUF4832,DUF4978,FIVAR,Glyco_hydro_42,Glyco_hydro_42M
TH3_k127_73585_5	583355.Caka_3109	1.461e-218	743.0	COG2312@1|root,COG3507@1|root,COG2312@2|Bacteria,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CBM_6,DUF1080,DUF1349,Erythro_esteras,GSDH,Glyco_hydro_43,LTD,Laminin_G_3,PKD,SLH
TH3_k127_73585_36	573061.Clocel_1966	1.959e-39	172.0	COG1409@1|root,COG1409@2|Bacteria,1VTEB@1239|Firmicutes,24E3Z@186801|Clostridia,36GZ8@31979|Clostridiaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
TH3_k127_73585_48	1396141.BATP01000007_gene5656	5.584e-07	64.0	COG2312@1|root,COG3506@1|root,COG2312@2|Bacteria,COG3506@2|Bacteria,46SQ1@74201|Verrucomicrobia,2IV3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_73585_47	1303518.CCALI_02038	6.815e-16	87.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_73585_12	886293.Sinac_4751	4.057e-145	477.0	COG0584@1|root,COG0584@2|Bacteria,2IXVA@203682|Planctomycetes	203682|Planctomycetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
TH3_k127_73585_42	1270193.JARP01000004_gene1522	2.929e-27	126.0	COG0823@1|root,COG0823@2|Bacteria,4NFQ0@976|Bacteroidetes,1I7I9@117743|Flavobacteriia,2NSYV@237|Flavobacterium	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	PD40,Pectate_lyase22
TH3_k127_73585_29	530564.Psta_3954	6.294e-61	221.0	COG4785@1|root,COG4785@2|Bacteria,2IZYN@203682|Planctomycetes	203682|Planctomycetes	S	May be involved in cell division	-	-	-	ko:K05803	-	-	-	-	ko00000	-	-	-	TPR_16
TH3_k127_73585_20	595460.RRSWK_04460	4.307e-104	346.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
TH3_k127_73585_22	530564.Psta_2822	5.007e-96	329.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_73585_6	1123508.JH636450_gene7203	1.979e-206	666.0	COG3356@1|root,COG3356@2|Bacteria,2IXDY@203682|Planctomycetes	203682|Planctomycetes	G	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk,Laminin_G_3
TH3_k127_73585_35	1536773.R70331_08785	8.813e-44	176.0	COG1520@1|root,COG1520@2|Bacteria,1UIHU@1239|Firmicutes,4ISIB@91061|Bacilli,2773B@186822|Paenibacillaceae	91061|Bacilli	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_73585_43	1353531.AZNX01000014_gene3221	5.287e-24	116.0	COG2159@1|root,COG2159@2|Bacteria,1ND2I@1224|Proteobacteria,2UIP1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
TH3_k127_73585_13	1210884.HG799471_gene14593	5.195e-141	466.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXJQ@203682|Planctomycetes	203682|Planctomycetes	C	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk,Cytochrom_C
TH3_k127_73585_26	1142394.PSMK_12790	1.27e-82	286.0	COG0673@1|root,COG0673@2|Bacteria,2IY6G@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_73585_27	1142394.PSMK_13110	1.018e-72	256.0	COG1082@1|root,COG1082@2|Bacteria,2IXZ6@203682|Planctomycetes	203682|Planctomycetes	G	isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_73585_37	1120965.AUBV01000006_gene2184	3.482e-37	146.0	28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes,47NH9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_73585_16	1210884.HG799469_gene14163	4.832e-122	407.0	COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
TH3_k127_73585_39	96561.Dole_2048	6.012e-31	133.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42Q3J@68525|delta/epsilon subdivisions,2WP5U@28221|Deltaproteobacteria,2MKDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,YwqJ-deaminase
TH3_k127_73585_31	880072.Desac_0729	1.246e-59	226.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,2MQB5@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
TH3_k127_73585_30	1469245.JFBG01000044_gene1864	2.564e-60	218.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria,1WYE1@135613|Chromatiales	135613|Chromatiales	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
TH3_k127_73585_8	639030.JHVA01000001_gene2781	5.512e-173	555.0	COG0673@1|root,COG0673@2|Bacteria,3Y6C9@57723|Acidobacteria,2JKU9@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_73585_44	290397.Adeh_1033	7.634e-23	107.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TH3_k127_73585_25	225849.swp_0274	1.642e-83	287.0	2910Q@1|root,2ZNNC@2|Bacteria,1PCP3@1224|Proteobacteria,1S0BX@1236|Gammaproteobacteria,2Q953@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_73585_32	1395513.P343_05500	3.917e-50	185.0	COG1704@1|root,COG1704@2|Bacteria,1V3R9@1239|Firmicutes,4IR1H@91061|Bacilli,26PKG@186821|Sporolactobacillaceae	91061|Bacilli	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
TH3_k127_73585_40	479435.Kfla_6730	9.829e-31	131.0	2CPKI@1|root,32SJC@2|Bacteria,2IQPS@201174|Actinobacteria,4DS6U@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
TH3_k127_73585_33	382464.ABSI01000010_gene3387	2.225e-48	182.0	COG0564@1|root,COG0564@2|Bacteria,46V2B@74201|Verrucomicrobia,2IU67@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
TH3_k127_73585_23	595460.RRSWK_03709	1.11e-91	328.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2IYMF@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
TH3_k127_73585_38	497964.CfE428DRAFT_2131	1.439e-36	147.0	29NX7@1|root,309VB@2|Bacteria,46WPG@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_73585_41	1128421.JAGA01000002_gene1111	2.764e-29	122.0	COG0622@1|root,COG0622@2|Bacteria,2NQ04@2323|unclassified Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
TH3_k127_73585_34	483219.LILAB_36295	1.421e-44	180.0	COG0204@1|root,COG0204@2|Bacteria,1R72B@1224|Proteobacteria,433XW@68525|delta/epsilon subdivisions,2X411@28221|Deltaproteobacteria,2YXVN@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TH3_k127_73585_24	313628.LNTAR_05744	1.944e-85	301.0	COG0815@1|root,COG0815@2|Bacteria	2|Bacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
TH3_k127_73585_0	204669.Acid345_4052	0.0	1355.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
TH3_k127_73585_19	521674.Plim_3779	4.339e-109	369.0	COG2755@1|root,COG2755@2|Bacteria,2IZBK@203682|Planctomycetes	203682|Planctomycetes	E	Pectate lyase	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Pec_lyase
TH3_k127_73585_1	497964.CfE428DRAFT_0772	1.937e-248	797.0	COG0457@1|root,COG0457@2|Bacteria,46U9B@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2,TPR_16,TPR_19
TH3_k127_73585_18	344747.PM8797T_32255	2.685e-110	363.0	2DBN7@1|root,2ZA2Y@2|Bacteria,2IYBW@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
TH3_k127_73585_10	886293.Sinac_0405	6.448e-156	498.0	COG0714@1|root,COG0714@2|Bacteria,2IX8Y@203682|Planctomycetes	203682|Planctomycetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TH3_k127_73585_17	497964.CfE428DRAFT_0775	8.763e-122	398.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TH3_k127_73585_7	497964.CfE428DRAFT_0777	3.402e-178	584.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
TH3_k127_73585_4	886293.Sinac_0402	9.005e-224	740.0	COG1196@1|root,COG1196@2|Bacteria,2IYCW@203682|Planctomycetes	203682|Planctomycetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_73585_3	1123242.JH636434_gene3690	1.382e-224	721.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2IWWQ@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
TH3_k127_73585_21	886293.Sinac_0400	1.707e-103	355.0	COG4249@1|root,COG4249@2|Bacteria,2IZ2A@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_73585_9	330214.NIDE3012	2.15e-159	511.0	COG1089@1|root,COG1089@2|Bacteria,3J0YR@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
TH3_k127_73585_15	1123277.KB893193_gene3895	2.001e-129	422.0	COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,47KAF@768503|Cytophagia	976|Bacteroidetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
TH3_k127_73585_45	497964.CfE428DRAFT_4965	1.184e-17	87.0	COG2165@1|root,COG2165@2|Bacteria,46T8M@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
TH3_k127_73585_46	497964.CfE428DRAFT_4965	5.084e-17	85.0	COG2165@1|root,COG2165@2|Bacteria,46T8M@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
TH3_k127_7381314_24	1403819.BATR01000167_gene5697	1.06e-26	118.0	COG2453@1|root,COG2453@2|Bacteria,46XSU@74201|Verrucomicrobia,2IWHI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Protein-tyrosine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
TH3_k127_7381314_34	497964.CfE428DRAFT_5371	4.278e-05	53.0	COG4121@1|root,COG4121@2|Bacteria	2|Bacteria	E	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363	2.1.1.61,2.1.1.72,2.4.2.29,4.2.1.151	ko:K00773,ko:K07319,ko:K11782,ko:K15461	ko00130,ko01110,map00130,map01110	-	R00601,R03789,R08702,R10209,R10666	RC00003,RC00053,RC00060,RC00063,RC01483,RC03232	ko00000,ko00001,ko01000,ko02048,ko03016	-	-	-	DAO,Methyltransf_30
TH3_k127_7381314_15	1122927.KB895429_gene355	3.188e-80	275.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,26SGI@186822|Paenibacillaceae	91061|Bacilli	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	pabA	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
TH3_k127_7381314_27	331678.Cphamn1_0275	3.417e-20	98.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
TH3_k127_7381314_29	452637.Oter_2961	1.939e-15	79.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005981,GO:0006109,GO:0006793,GO:0006796,GO:0006810,GO:0008047,GO:0008150,GO:0008152,GO:0008643,GO:0008965,GO:0008982,GO:0009401,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0010675,GO:0010676,GO:0010906,GO:0010907,GO:0015144,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0019197,GO:0019222,GO:0022804,GO:0022857,GO:0030234,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032881,GO:0032991,GO:0034219,GO:0043085,GO:0043467,GO:0043470,GO:0043471,GO:0044093,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045819,GO:0045913,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051179,GO:0051234,GO:0055085,GO:0060255,GO:0062012,GO:0062013,GO:0065007,GO:0065009,GO:0070873,GO:0070875,GO:0071702,GO:0080090,GO:0098772	-	ko:K02784,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1,8.A.8.1.1	-	e_coli_core.b2415,iAF1260.b2415,iB21_1397.B21_02276,iBWG_1329.BWG_2177,iE2348C_1286.E2348C_2601,iEC042_1314.EC042_2624,iEC55989_1330.EC55989_2705,iECABU_c1320.ECABU_c27360,iECBD_1354.ECBD_1266,iECB_1328.ECB_02315,iECDH10B_1368.ECDH10B_2580,iECDH1ME8569_1439.ECDH1ME8569_2349,iECDH1ME8569_1439.EcDH1_1246,iECD_1391.ECD_02315,iECED1_1282.ECED1_2859,iECH74115_1262.ECH74115_3646,iECIAI1_1343.ECIAI1_2473,iECIAI39_1322.ECIAI39_2561,iECNA114_1301.ECNA114_2492,iECO103_1326.ECO103_2934,iECO111_1330.ECO111_3145,iECO26_1355.ECO26_3468,iECOK1_1307.ECOK1_2732,iECP_1309.ECP_2439,iECS88_1305.ECS88_2605,iECSE_1348.ECSE_2706,iECSF_1327.ECSF_2279,iECSP_1301.ECSP_3363,iECUMN_1333.ECUMN_2737,iECW_1372.ECW_m2644,iECs_1301.ECs3287,iEKO11_1354.EKO11_1313,iETEC_1333.ETEC_2528,iEcDH1_1363.EcDH1_1246,iEcE24377_1341.EcE24377A_2702,iEcHS_1320.EcHS_A2550,iEcSMS35_1347.EcSMS35_2570,iEcolC_1368.EcolC_1263,iG2583_1286.G2583_2947,iJO1366.b2415,iJR904.b2415,iLF82_1304.LF82_1769,iNRG857_1313.NRG857_12110,iPC815.YPO2993,iSBO_1134.SBO_2439,iSDY_1059.SDY_2612,iSFV_1184.SFV_2467,iSF_1195.SF2470,iSFxv_1172.SFxv_2719,iSSON_1240.SSON_2504,iS_1188.S2616,iSbBS512_1146.SbBS512_E2765,iUMN146_1321.UM146_04545,iUMNK88_1353.UMNK88_3017,iUTI89_1310.UTI89_C2749,iWFL_1372.ECW_m2644,iY75_1357.Y75_RS12655,iZ_1308.Z3681,ic_1306.c2950	PTS-HPr
TH3_k127_7381314_25	497964.CfE428DRAFT_5080	3.794e-26	116.0	29N11@1|root,344HT@2|Bacteria,46WBB@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7381314_10	497964.CfE428DRAFT_5081	7.434e-150	488.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TH3_k127_7381314_5	1396141.BATP01000003_gene5036	4.888e-284	930.0	COG2931@1|root,COG3299@1|root,COG4733@1|root,COG5267@1|root,COG2931@2|Bacteria,COG3299@2|Bacteria,COG4733@2|Bacteria,COG5267@2|Bacteria,46TXW@74201|Verrucomicrobia,2IWPZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	PA14	-	-	-	-	-	-	-	-	-	-	-	-	PA14
TH3_k127_7381314_17	1499967.BAYZ01000062_gene6031	3.158e-77	281.0	28K2M@1|root,2Z9RY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TH3_k127_7381314_35	458817.Shal_3325	7.812e-05	55.0	COG4932@1|root,COG4932@2|Bacteria,1R94W@1224|Proteobacteria,1RSPU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7381314_22	1123508.JH636441_gene3117	5.244e-34	141.0	COG1413@1|root,COG1413@2|Bacteria,2J2VX@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_7381314_9	1382359.JIAL01000001_gene1319	4.456e-176	566.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	prnC	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
TH3_k127_7381314_4	861299.J421_1753	1.238e-285	921.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
TH3_k127_7381314_1	344747.PM8797T_03935	0.0	1101.0	COG0457@1|root,COG0457@2|Bacteria,2IXP3@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,TPR_16
TH3_k127_7381314_7	243090.RB11088	1.772e-206	662.0	COG0457@1|root,COG0457@2|Bacteria,2IYBX@203682|Planctomycetes	203682|Planctomycetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
TH3_k127_7381314_0	452637.Oter_2954	0.0	1242.0	COG0457@1|root,COG0457@2|Bacteria	452637.Oter_2954|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7381314_31	324057.Pjdr2_2563	7.648e-09	70.0	COG4447@1|root,COG4733@1|root,COG5297@1|root,COG4447@2|Bacteria,COG4733@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	dex	-	3.2.1.11	ko:K05988,ko:K06882	ko00500,map00500	-	R11309	-	ko00000,ko00001,ko01000	-	GH66	-	fn3
TH3_k127_7381314_33	1403819.BATR01000069_gene2031	9.896e-06	59.0	COG1470@1|root,COG1749@1|root,COG3291@1|root,COG3506@1|root,COG3533@1|root,COG1470@2|Bacteria,COG1749@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria,COG3533@2|Bacteria,46SQ1@74201|Verrucomicrobia,2IV3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7381314_3	861299.J421_1753	9.264e-290	933.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
TH3_k127_7381314_2	861299.J421_1753	9.439e-294	943.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
TH3_k127_7381314_13	1288963.ADIS_1386	4.322e-103	369.0	28HHT@1|root,2Z7TE@2|Bacteria,4NIHS@976|Bacteroidetes,47MAA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7381314_23	580331.Thit_1725	1.611e-33	151.0	COG0412@1|root,COG0412@2|Bacteria,1TQQS@1239|Firmicutes,24DCW@186801|Clostridia,42FHF@68295|Thermoanaerobacterales	186801|Clostridia	Q	Abhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_7,BAAT_C
TH3_k127_7381314_8	452637.Oter_2942	9.573e-204	652.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
TH3_k127_7381314_21	234267.Acid_6078	1.007e-35	153.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PD40,SdrD_B
TH3_k127_7381314_12	335543.Sfum_1622	1.083e-128	438.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1R7E0@1224|Proteobacteria,42XD8@68525|delta/epsilon subdivisions,2WT8U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_C554
TH3_k127_7381314_19	234267.Acid_6081	4.599e-71	254.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,HATPase_c,PKD_3,Reg_prop
TH3_k127_7381314_18	335543.Sfum_1620	1.401e-75	271.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TH3_k127_7381314_32	1121406.JAEX01000009_gene2643	3.715e-06	59.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42QZ1@68525|delta/epsilon subdivisions,2WKYF@28221|Deltaproteobacteria,2MA59@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TH3_k127_7381314_26	1541065.JRFE01000058_gene5541	5.331e-22	104.0	2DBIE@1|root,32ZYG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7381314_11	518766.Rmar_1438	4.036e-135	462.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_1438|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7381314_6	518766.Rmar_1439	1.143e-235	749.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_1439|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7381314_14	234267.Acid_0753	1.417e-83	291.0	COG0673@1|root,COG0673@2|Bacteria,3Y4KS@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_7381314_20	1410620.SHLA_36c000140	4.438e-61	222.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_7381314_36	1158146.KB907123_gene599	0.0009561	48.0	COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1WWJD@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP)	tmcA	-	2.3.1.193	ko:K06957	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3
TH3_k127_7381314_28	497964.CfE428DRAFT_5353	3.573e-20	109.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
TH3_k127_7381314_30	1219084.AP014508_gene1338	1.081e-14	91.0	COG0745@1|root,COG0745@2|Bacteria,2GDAM@200918|Thermotogae	200918|Thermotogae	T	PFAM response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
TH3_k127_7381314_16	428125.CLOLEP_03042	3.249e-80	285.0	COG3693@1|root,COG3693@2|Bacteria,1UZWX@1239|Firmicutes,24BPR@186801|Clostridia	186801|Clostridia	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_10
TH3_k127_7411591_3	1267535.KB906767_gene241	8.008e-54	218.0	COG3345@1|root,COG3345@2|Bacteria,3Y3UB@57723|Acidobacteria,2JKQN@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM Glycoside hydrolase, clan GH-D	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase
TH3_k127_7411591_4	67373.JOBF01000011_gene3329	3.514e-34	153.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,CBM_6,F5_F8_type_C,FIVAR,Glyco_hydro_106,Glyco_hydro_28,Melibiase_2,NAGLU,NAGLU_C,NAGLU_N
TH3_k127_7411591_0	1403819.BATR01000147_gene5026	1.754e-146	477.0	COG2897@1|root,COG2897@2|Bacteria,46WQ7@74201|Verrucomicrobia,2IW3E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7411591_1	1235803.C825_02924	8.864e-121	417.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,2FMUE@200643|Bacteroidia,230PE@171551|Porphyromonadaceae	976|Bacteroidetes	G	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_20b,Glyco_hydro_67N
TH3_k127_7411591_2	530564.Psta_4378	1.968e-71	242.0	COG4409@1|root,COG4409@2|Bacteria,2IXPZ@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TH3_k127_7454427_8	497964.CfE428DRAFT_3194	3.89e-35	141.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
TH3_k127_7454427_1	1123242.JH636434_gene5339	1.827e-178	570.0	COG0673@1|root,COG0673@2|Bacteria,2IXA3@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_7454427_4	1123242.JH636434_gene5340	1.594e-111	385.0	COG1413@1|root,COG1413@2|Bacteria,2IZE1@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
TH3_k127_7454427_0	382464.ABSI01000009_gene3989	7.217e-183	594.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	BAAT_C,Hydrolase_4
TH3_k127_7454427_3	497964.CfE428DRAFT_0801	3.64e-121	398.0	COG4586@1|root,COG4586@2|Bacteria,46TXF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_7454427_2	794903.OPIT5_00465	1.469e-142	467.0	COG0593@1|root,COG0593@2|Bacteria,46S6H@74201|Verrucomicrobia,3K7HJ@414999|Opitutae	414999|Opitutae	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
TH3_k127_7454427_6	497964.CfE428DRAFT_6239	4.062e-53	188.0	COG0347@1|root,COG0347@2|Bacteria,46VXS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	P-II
TH3_k127_7454427_9	530564.Psta_1718	8.456e-23	101.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
TH3_k127_7454427_10	246196.MSMEI_6436	1.464e-12	77.0	COG1408@1|root,COG1408@2|Bacteria,2GMST@201174|Actinobacteria,233E3@1762|Mycobacteriaceae	201174|Actinobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
TH3_k127_7454427_5	96561.Dole_0975	7.75e-59	210.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42SS8@68525|delta/epsilon subdivisions,2WPMH@28221|Deltaproteobacteria,2MPU9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
TH3_k127_7454427_7	1077285.AGDG01000002_gene2066	2.473e-49	182.0	COG0613@1|root,COG0613@2|Bacteria,4NHZ5@976|Bacteroidetes,2FQW5@200643|Bacteroidia,4AN9D@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	DUF5001
TH3_k127_7458515_5	1121957.ATVL01000014_gene1459	2.488e-149	509.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7458515_0	497964.CfE428DRAFT_1084	9.291e-301	942.0	COG1966@1|root,COG1966@2|Bacteria,46SC3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	5TM C-terminal transporter carbon starvation CstA	-	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
TH3_k127_7458515_3	234267.Acid_6938	1.153e-150	488.0	COG5368@1|root,COG5368@2|Bacteria,3Y2MM@57723|Acidobacteria	57723|Acidobacteria	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
TH3_k127_7458515_10	452637.Oter_1760	6.265e-43	163.0	COG1057@1|root,COG1057@2|Bacteria,46T27@74201|Verrucomicrobia,3K85U@414999|Opitutae	414999|Opitutae	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
TH3_k127_7458515_12	237368.SCABRO_02951	4.18e-29	121.0	COG0799@1|root,COG0799@2|Bacteria,2J0AM@203682|Planctomycetes	203682|Planctomycetes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
TH3_k127_7458515_13	1156937.MFUM_200030	6.367e-20	93.0	2DFNJ@1|root,2ZSFW@2|Bacteria,46WS2@74201|Verrucomicrobia,37HAT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	PurA ssDNA and RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PurA
TH3_k127_7458515_4	269799.Gmet_1302	8.428e-150	485.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,43UHM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	SMART Nucleotide binding protein, PINc	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
TH3_k127_7458515_11	1403819.BATR01000061_gene1887	9.147e-41	162.0	COG0625@1|root,COG0625@2|Bacteria,46SQB@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
TH3_k127_7458515_15	886293.Sinac_6824	6.501e-15	83.0	28WRV@1|root,2ZIRK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7458515_14	257313.BP2758	1.427e-19	99.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2VSCK@28216|Betaproteobacteria,3T4GB@506|Alcaligenaceae	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
TH3_k127_7458515_1	452637.Oter_0618	1.106e-282	883.0	COG3591@1|root,COG3591@2|Bacteria,46UUQ@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
TH3_k127_7458515_6	497964.CfE428DRAFT_6510	1.987e-135	444.0	COG0845@1|root,COG0845@2|Bacteria,46SKN@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
TH3_k127_7458515_9	452637.Oter_1638	6.607e-107	351.0	COG1136@1|root,COG1136@2|Bacteria,46SI5@74201|Verrucomicrobia,3K7NZ@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_7458515_8	497964.CfE428DRAFT_6512	1.833e-120	399.0	COG0577@1|root,COG0577@2|Bacteria,46SK8@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TH3_k127_7458515_7	497964.CfE428DRAFT_6513	9.188e-134	439.0	COG0577@1|root,COG0577@2|Bacteria,46SPG@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TH3_k127_7458515_2	861299.J421_0351	2.267e-175	565.0	COG1129@1|root,COG1129@2|Bacteria,1ZVAU@142182|Gemmatimonadetes	2|Bacteria	G	ABC transporter	rbsA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
TH3_k127_7458599_3	452637.Oter_4248	7.748e-20	95.0	COG5184@1|root,COG5184@2|Bacteria,46Z7H@74201|Verrucomicrobia,3K9VS@414999|Opitutae	2|Bacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,RCC1,RCC1_2
TH3_k127_7458599_2	945713.IALB_2754	2.411e-90	315.0	COG3104@1|root,COG3104@2|Bacteria	2|Bacteria	E	oligopeptide transport	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	MFS_1,PTR2
TH3_k127_7458599_0	497964.CfE428DRAFT_3359	5.329e-245	770.0	COG0539@1|root,COG0539@2|Bacteria,46SFY@74201|Verrucomicrobia	74201|Verrucomicrobia	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
TH3_k127_7458599_1	497964.CfE428DRAFT_0727	1.831e-235	738.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,46UC6@74201|Verrucomicrobia	74201|Verrucomicrobia	C	IMP dehydrogenase GMP reductase	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
TH3_k127_7461144_39	1396141.BATP01000059_gene2560	0.0002298	44.0	COG0167@1|root,COG0167@2|Bacteria,46V5R@74201|Verrucomicrobia	74201|Verrucomicrobia	CF	Dihydroorotate dehydrogenase	-	-	1.3.1.1	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21
TH3_k127_7461144_4	1396141.BATP01000059_gene2565	1.405e-209	662.0	COG1012@1|root,COG1012@2|Bacteria,46TX0@74201|Verrucomicrobia,2IUT7@203494|Verrucomicrobiae	2|Bacteria	C	Aldehyde dehydrogenase family	mmsA	GO:0000166,GO:0003674,GO:0003824,GO:0004029,GO:0004030,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0006066,GO:0006067,GO:0006069,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0022900,GO:0031974,GO:0034308,GO:0036094,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0050896,GO:0051287,GO:0055114,GO:0070013,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901615	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_4667,iYL1228.KPN_04670	Aldedh
TH3_k127_7461144_3	452637.Oter_0622	2.544e-224	708.0	COG0160@1|root,COG0160@2|Bacteria,46TE8@74201|Verrucomicrobia,3KA3D@414999|Opitutae	2|Bacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	dgdA	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3,Peptidase_M23
TH3_k127_7461144_17	1131269.AQVV01000001_gene1323	1.477e-73	263.0	2DRTQ@1|root,32URN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7461144_13	497964.CfE428DRAFT_5470	1.061e-97	334.0	COG2204@1|root,COG2204@2|Bacteria,46VVS@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TH3_k127_7461144_5	497964.CfE428DRAFT_5468	4.276e-191	620.0	COG5000@1|root,COG5000@2|Bacteria,46THS@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
TH3_k127_7461144_12	382464.ABSI01000020_gene123	1.879e-101	344.0	COG3437@1|root,COG3437@2|Bacteria,46Z3C@74201|Verrucomicrobia,2IUIF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
TH3_k127_7461144_21	402626.Rpic_2975	7.785e-62	231.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VZJ3@28216|Betaproteobacteria,1JZS4@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	phcS	-	2.7.13.3	ko:K19621	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TH3_k127_7461144_9	382464.ABSI01000020_gene121	7.562e-121	403.0	COG0500@1|root,COG0500@2|Bacteria,46YTR@74201|Verrucomicrobia,2IU3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Response_reg
TH3_k127_7461144_22	1458357.BG58_34255	9.907e-58	220.0	COG3659@1|root,COG3659@2|Bacteria,1QMC3@1224|Proteobacteria,2VMG2@28216|Betaproteobacteria,1K0VE@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM Carbohydrate-selective porin OprB	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
TH3_k127_7461144_28	526222.Desal_3013	1.327e-32	141.0	COG2898@1|root,COG2898@2|Bacteria,1N1JA@1224|Proteobacteria	1224|Proteobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504	2.A.1.3.37	-	-	DUF2156
TH3_k127_7461144_16	349521.HCH_05076	2.833e-76	266.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ycjY	GO:0008150,GO:0009987,GO:0051301	-	ko:K01990,ko:K06889	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	DLH,Hydrolase_4,Peptidase_S15
TH3_k127_7461144_24	243231.GSU1004	3.483e-45	178.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,43T97@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Nitrogen fixation master sensor histidine kinase, PAS domain-containing	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
TH3_k127_7461144_14	240016.ABIZ01000001_gene2650	3.144e-97	345.0	COG1452@1|root,COG1452@2|Bacteria,46SJX@74201|Verrucomicrobia,2ITQV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	-
TH3_k127_7461144_32	111780.Sta7437_2149	1.855e-16	90.0	2CFCI@1|root,32S1P@2|Bacteria,1G4ST@1117|Cyanobacteria,3VJTA@52604|Pleurocapsales	1117|Cyanobacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
TH3_k127_7461144_11	1158318.ATXC01000001_gene495	2.821e-118	399.0	COG0113@1|root,COG0113@2|Bacteria,2G3MJ@200783|Aquificae	200783|Aquificae	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
TH3_k127_7461144_35	290397.Adeh_3650	3.967e-12	73.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,BTAD,DUF4242,FHA,Guanylate_cyc,Trans_reg_C
TH3_k127_7461144_8	1403819.BATR01000184_gene6355	5.222e-142	461.0	COG0505@1|root,COG0505@2|Bacteria,46TDX@74201|Verrucomicrobia,2ITTA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
TH3_k127_7461144_25	794903.OPIT5_07630	2.927e-44	166.0	COG0526@1|root,COG0526@2|Bacteria,46SXQ@74201|Verrucomicrobia,3K8IG@414999|Opitutae	414999|Opitutae	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
TH3_k127_7461144_7	497964.CfE428DRAFT_2609	1.896e-169	544.0	COG0044@1|root,COG0044@2|Bacteria,46S78@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
TH3_k127_7461144_38	1462527.CCDM010000002_gene685	5.188e-05	48.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7461144_6	518766.Rmar_0899	5.107e-184	594.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1FIYP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
TH3_k127_7461144_18	338963.Pcar_1946	4.065e-69	242.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,43TY0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cytidylyltransferase	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
TH3_k127_7461144_2	497964.CfE428DRAFT_3303	1.712e-236	743.0	COG0504@1|root,COG0504@2|Bacteria,46S8K@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
TH3_k127_7461144_40	1210884.HG799464_gene10719	0.000488	51.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4132,HEAT_2
TH3_k127_7461144_36	1210884.HG799464_gene10957	2.497e-11	75.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
TH3_k127_7461144_33	1209989.TepiRe1_1613	5.922e-15	77.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,42EM6@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
TH3_k127_7461144_37	489825.LYNGBM3L_48350	1.164e-06	53.0	COG2405@1|root,COG2405@2|Bacteria,1G725@1117|Cyanobacteria,1HATZ@1150|Oscillatoriales	1117|Cyanobacteria	S	nucleic acid-binding protein	-	-	-	ko:K07066	-	-	-	-	ko00000	-	-	-	DUF3368
TH3_k127_7461144_31	1123277.KB893217_gene4667	4.866e-19	91.0	COG2405@1|root,COG2405@2|Bacteria,4NVKA@976|Bacteroidetes,47X58@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF3368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
TH3_k127_7461144_15	555079.Toce_0685	1.631e-96	332.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,42EM6@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
TH3_k127_7461144_30	395493.BegalDRAFT_0545	3.625e-21	99.0	COG5652@1|root,COG5652@2|Bacteria,1N1BF@1224|Proteobacteria,1SBGK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
TH3_k127_7461144_0	118168.MC7420_356	0.0	1087.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1H87F@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
TH3_k127_7461144_27	1125863.JAFN01000001_gene2910	5.401e-35	143.0	COG1011@1|root,COG1011@2|Bacteria,1NIPN@1224|Proteobacteria	1224|Proteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
TH3_k127_7461144_23	583355.Caka_1740	1.995e-45	175.0	2CAZH@1|root,2Z7RU@2|Bacteria,46V42@74201|Verrucomicrobia,3K7Z0@414999|Opitutae	414999|Opitutae	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
TH3_k127_7461144_1	452637.Oter_0670	0.0	1019.0	COG1053@1|root,COG1053@2|Bacteria,46S7D@74201|Verrucomicrobia,3K754@414999|Opitutae	414999|Opitutae	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
TH3_k127_7461144_10	452637.Oter_0669	1.082e-118	385.0	COG0479@1|root,COG0479@2|Bacteria,46S82@74201|Verrucomicrobia,3K7PU@414999|Opitutae	414999|Opitutae	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
TH3_k127_7461144_26	530564.Psta_0778	4.661e-39	149.0	COG1832@1|root,COG1832@2|Bacteria,2J066@203682|Planctomycetes	203682|Planctomycetes	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
TH3_k127_7461144_20	180332.JTGN01000022_gene1511	8.971e-63	229.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,24G9W@186801|Clostridia	186801|Clostridia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_7461144_19	316067.Geob_1422	1.228e-63	223.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,43RZH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
TH3_k127_7463246_8	717605.Theco_3395	2.036e-23	109.0	COG2931@1|root,COG2931@2|Bacteria,1V022@1239|Firmicutes,4HFJ6@91061|Bacilli,26SF3@186822|Paenibacillaceae	91061|Bacilli	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TH3_k127_7463246_11	926560.KE387028_gene234	5.622e-05	48.0	COG0286@1|root,COG0286@2|Bacteria,1WI3E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
TH3_k127_7463246_7	497964.CfE428DRAFT_1407	3.294e-26	115.0	COG0582@1|root,COG0582@2|Bacteria,46W0S@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
TH3_k127_7463246_4	335543.Sfum_0920	5.391e-67	241.0	COG0500@1|root,COG1846@1|root,COG1846@2|Bacteria,COG2226@2|Bacteria,1MW7J@1224|Proteobacteria,43BRY@68525|delta/epsilon subdivisions,2X72R@28221|Deltaproteobacteria,2MQCD@213462|Syntrophobacterales	28221|Deltaproteobacteria	KQ	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
TH3_k127_7463246_9	324602.Caur_0299	1.127e-22	115.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
TH3_k127_7463246_10	264462.Bd2582	2.083e-05	58.0	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,1NED3@1224|Proteobacteria,42WDX@68525|delta/epsilon subdivisions,2MTVC@213481|Bdellovibrionales,2WRDH@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	cell wall surface anchor family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
TH3_k127_7463246_5	251221.35210810	1.127e-53	213.0	COG5295@1|root,COG5295@2|Bacteria,1GB93@1117|Cyanobacteria	1117|Cyanobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7463246_12	713587.THITH_06560	8.226e-05	45.0	COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,1RRUE@1236|Gammaproteobacteria,1X1AV@135613|Chromatiales	135613|Chromatiales	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
TH3_k127_7463246_2	743299.Acife_2330	2.928e-141	464.0	COG3385@1|root,COG3385@2|Bacteria,1RA6A@1224|Proteobacteria,1SDJ1@1236|Gammaproteobacteria,2NDQ9@225057|Acidithiobacillales	225057|Acidithiobacillales	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
TH3_k127_7463246_1	1150600.ADIARSV_0055	1.803e-242	774.0	28MHM@1|root,2ZAUH@2|Bacteria,4NKMG@976|Bacteroidetes,1IWWX@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7463246_3	1123242.JH636434_gene4801	8.493e-110	362.0	COG1028@1|root,COG1028@2|Bacteria	1123242.JH636434_gene4801|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7463246_0	1303518.CCALI_02122	7.331e-244	791.0	2C33Y@1|root,33VR5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7463246_6	443143.GM18_2869	5.066e-31	125.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,42M86@68525|delta/epsilon subdivisions,2WIT1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
TH3_k127_7463894_15	1303518.CCALI_00378	1.155e-11	73.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_7463894_12	1444309.JAQG01000181_gene3484	8.357e-34	147.0	COG2833@1|root,COG2833@2|Bacteria,1W5BJ@1239|Firmicutes,4I0UF@91061|Bacilli,26VKN@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
TH3_k127_7463894_9	1499967.BAYZ01000017_gene6249	2.372e-62	228.0	COG0407@1|root,COG0407@2|Bacteria,2NP39@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
TH3_k127_7463894_5	97139.C824_01928	2.167e-86	300.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,36F4R@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_7463894_10	497964.CfE428DRAFT_2346	1.665e-52	198.0	COG3694@1|root,COG3694@2|Bacteria,46VPX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
TH3_k127_7463894_6	497964.CfE428DRAFT_2347	1.405e-71	251.0	COG4587@1|root,COG4587@2|Bacteria,46VAG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
TH3_k127_7463894_0	1519464.HY22_04590	4.086e-242	768.0	COG0058@1|root,COG0058@2|Bacteria,1FD8Y@1090|Chlorobi	1090|Chlorobi	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
TH3_k127_7463894_1	886293.Sinac_6975	1.502e-153	499.0	28KPG@1|root,2ZA7K@2|Bacteria,2J1E2@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7463894_4	521674.Plim_2302	2.149e-93	321.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
TH3_k127_7463894_3	240016.ABIZ01000001_gene4766	5.514e-119	390.0	COG0492@1|root,COG0492@2|Bacteria,46SC1@74201|Verrucomicrobia,2ITP4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TH3_k127_7463894_14	497964.CfE428DRAFT_4596	2.342e-21	110.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K02283,ko:K02454,ko:K03220,ko:K03466	ko03070,ko05111,map03070,map05111	M00331,M00332	-	-	ko00000,ko00001,ko00002,ko02035,ko02044,ko03036	3.A.12,3.A.15,3.A.6.1	-	-	Cytochrom_c3_2,FHA,FtsK_SpoIIIE,Response_reg,T2SSE,Yop-YscD_cpl,Yop-YscD_ppl
TH3_k127_7463894_13	497964.CfE428DRAFT_5353	1.199e-23	118.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
TH3_k127_7463894_11	452637.Oter_0887	1.245e-43	180.0	COG4726@1|root,COG4726@2|Bacteria,46VER@74201|Verrucomicrobia,3K9MT@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7463894_7	497964.CfE428DRAFT_5952	1.766e-71	250.0	COG0745@1|root,COG0745@2|Bacteria,46V5I@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TH3_k127_7463894_2	497964.CfE428DRAFT_5953	3.156e-120	408.0	COG0642@1|root,COG2205@2|Bacteria,46Z6V@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TH3_k127_7463894_8	595460.RRSWK_04460	4.065e-69	254.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
TH3_k127_7463894_16	519989.ECTPHS_00480	1.274e-05	51.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1WW1X@135613|Chromatiales	135613|Chromatiales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
TH3_k127_7468569_4	497964.CfE428DRAFT_1215	8.69e-96	316.0	COG1100@1|root,COG1100@2|Bacteria,46VDZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Ras family	-	-	-	-	-	-	-	-	-	-	-	-	Arf
TH3_k127_7468569_12	497964.CfE428DRAFT_1216	8.747e-31	127.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
TH3_k127_7468569_17	1396141.BATP01000030_gene3719	2.661e-18	102.0	COG3119@1|root,COG3211@1|root,COG3656@1|root,COG5337@1|root,COG3119@2|Bacteria,COG3211@2|Bacteria,COG3656@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	phoX	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	CotH,DUF839
TH3_k127_7468569_0	1396141.BATP01000003_gene4934	1.309e-174	609.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
TH3_k127_7468569_11	452637.Oter_3202	1.441e-39	151.0	COG1869@1|root,COG1869@2|Bacteria,46VR5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	RbsD / FucU transport protein family	-	-	5.4.99.62	ko:K06726	ko02010,map02010	-	R08247	RC02247	ko00000,ko00001,ko01000	-	-	-	RbsD_FucU
TH3_k127_7468569_18	661478.OP10G_1142	8.907e-14	82.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_7468569_6	1122165.AUHS01000023_gene237	1.046e-65	241.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RXSU@1236|Gammaproteobacteria,1JDJP@118969|Legionellales	118969|Legionellales	M	lipid A biosynthesis	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
TH3_k127_7468569_2	297246.lpp0427	5.978e-99	342.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1JD6F@118969|Legionellales	118969|Legionellales	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TH3_k127_7468569_9	1430331.EP10_03500	1.158e-42	160.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,1WE7S@129337|Geobacillus	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iSB619.SA_RS04785	Ketoacyl-synt_C,ketoacyl-synt
TH3_k127_7468569_3	1122169.AREN01000031_gene1457	4.097e-98	329.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1JDCZ@118969|Legionellales	118969|Legionellales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TH3_k127_7468569_15	1122164.JHWF01000017_gene537	1.36e-20	102.0	COG0764@1|root,COG0764@2|Bacteria,1PCKD@1224|Proteobacteria,1SXNH@1236|Gammaproteobacteria,1JDAD@118969|Legionellales	118969|Legionellales	I	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA
TH3_k127_7468569_10	272624.lpg0359	2.637e-41	159.0	COG0236@1|root,COG0236@2|Bacteria,1NM9E@1224|Proteobacteria,1SINP@1236|Gammaproteobacteria,1JEJN@118969|Legionellales	118969|Legionellales	IQ	Phosphopantetheine attachment site	acpP_2	-	-	-	-	-	-	-	-	-	-	-	PP-binding
TH3_k127_7468569_7	344747.PM8797T_12848	4.638e-61	220.0	COG1028@1|root,COG1028@2|Bacteria,2IXE0@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TH3_k127_7468569_5	272624.lpg0358	4.046e-89	301.0	COG0623@1|root,COG0623@2|Bacteria,1N64Z@1224|Proteobacteria,1T3N8@1236|Gammaproteobacteria,1JC7V@118969|Legionellales	118969|Legionellales	I	KR domain	-	-	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TH3_k127_7468569_14	1254432.SCE1572_31120	3.249e-22	106.0	COG2020@1|root,COG2020@2|Bacteria,1QTC1@1224|Proteobacteria,437VD@68525|delta/epsilon subdivisions,2X34Z@28221|Deltaproteobacteria,2Z1RR@29|Myxococcales	28221|Deltaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
TH3_k127_7468569_13	471854.Dfer_1900	4.664e-28	130.0	COG4409@1|root,COG4409@2|Bacteria,4P66K@976|Bacteroidetes	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TH3_k127_7468569_19	582899.Hden_1369	0.0008954	52.0	COG3408@1|root,COG3408@2|Bacteria,1MUYU@1224|Proteobacteria,2TQK2@28211|Alphaproteobacteria,3N7PF@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	G	N-terminal domain of (some) glycogen debranching enzymes	MA20_17380	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,GDE_C,GDE_N_bis
TH3_k127_7468569_8	497964.CfE428DRAFT_4864	1.154e-55	210.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7468569_1	886293.Sinac_6489	5.528e-154	521.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
TH3_k127_7478395_30	497964.CfE428DRAFT_2927	1.645e-07	59.0	COG0206@1|root,COG0206@2|Bacteria,46UWD@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
TH3_k127_7478395_1	1396418.BATQ01000141_gene3343	0.0	1137.0	COG4946@1|root,COG4946@2|Bacteria,46TXN@74201|Verrucomicrobia,2IV9W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7478395_13	530564.Psta_2150	1.783e-110	374.0	COG1520@1|root,COG1520@2|Bacteria,2IYV0@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
TH3_k127_7478395_23	925775.XVE_4058	1.159e-35	142.0	COG2020@1|root,COG2020@2|Bacteria,1N936@1224|Proteobacteria,1SCXB@1236|Gammaproteobacteria,1X823@135614|Xanthomonadales	135614|Xanthomonadales	O	Methyltransferase	-	-	2.1.1.100	ko:K00587	ko00900,ko01130,map00900,map01130	-	R04496	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	PEMT
TH3_k127_7478395_3	1303518.CCALI_00290	0.0	1079.0	COG0542@1|root,COG0542@2|Bacteria	2|Bacteria	O	response to heat	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
TH3_k127_7478395_2	583355.Caka_1736	0.0	1086.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
TH3_k127_7478395_24	153721.MYP_3853	8.619e-33	150.0	COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NGK2@976|Bacteroidetes,47NR3@768503|Cytophagia	976|Bacteroidetes	NU	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
TH3_k127_7478395_32	768706.Desor_1391	1.93e-06	63.0	COG2247@1|root,COG3386@1|root,COG2247@2|Bacteria,COG3386@2|Bacteria,1VMQN@1239|Firmicutes	1239|Firmicutes	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
TH3_k127_7478395_27	1396141.BATP01000034_gene4198	3.447e-14	89.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
TH3_k127_7478395_25	1396141.BATP01000002_gene4848	2.559e-22	101.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,GSDH,Laminin_G_3,PA14
TH3_k127_7478395_14	478741.JAFS01000001_gene1963	3.678e-107	369.0	COG0358@1|root,COG0358@2|Bacteria,46S6C@74201|Verrucomicrobia,37GA0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
TH3_k127_7478395_31	111781.Lepto7376_2051	1.804e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,1G39E@1117|Cyanobacteria,1H8XZ@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2,TPR_8
TH3_k127_7478395_29	1121405.dsmv_3253	3.536e-12	79.0	COG0457@1|root,COG0457@2|Bacteria,1MZGK@1224|Proteobacteria,42US4@68525|delta/epsilon subdivisions,2X72T@28221|Deltaproteobacteria,2MPJC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide TPR_2	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
TH3_k127_7478395_26	880073.Calab_0868	3.686e-15	87.0	COG2006@1|root,COG2006@2|Bacteria,2NPI6@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
TH3_k127_7478395_4	575540.Isop_0569	1.264e-205	645.0	COG0673@1|root,COG0673@2|Bacteria,2IWTD@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_7478395_33	1452536.JARE01000052_gene1721	0.0002819	51.0	2EH4F@1|root,33AWE@2|Bacteria,2I6EJ@201174|Actinobacteria,4FTHX@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7478395_11	344747.PM8797T_17402	4.904e-155	499.0	COG1082@1|root,COG1082@2|Bacteria,2IY10@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_7478395_12	497964.CfE428DRAFT_0899	1.372e-127	419.0	COG0820@1|root,COG0820@2|Bacteria,46SBD@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
TH3_k127_7478395_21	1123376.AUIU01000011_gene924	1.047e-62	222.0	COG0118@1|root,COG0118@2|Bacteria,3J0K7@40117|Nitrospirae	40117|Nitrospirae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
TH3_k127_7478395_17	497964.CfE428DRAFT_1492	5.099e-89	297.0	COG0605@1|root,COG0605@2|Bacteria,46SQF@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
TH3_k127_7478395_5	497964.CfE428DRAFT_2099	1.22e-201	647.0	COG0488@1|root,COG0488@2|Bacteria,46UUC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
TH3_k127_7478395_22	886293.Sinac_0868	1.738e-37	148.0	COG5507@1|root,COG5507@2|Bacteria,2J071@203682|Planctomycetes	203682|Planctomycetes	S	NIPSNAP family containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
TH3_k127_7478395_8	478741.JAFS01000002_gene116	5.172e-168	548.0	COG1190@1|root,COG1190@2|Bacteria,46TIA@74201|Verrucomicrobia,37FUW@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
TH3_k127_7478395_10	240016.ABIZ01000001_gene2258	1.823e-155	495.0	COG5564@1|root,COG5564@2|Bacteria,46TKF@74201|Verrucomicrobia,2IVH6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phosphoenolpyruvate hydrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	PEP_hydrolase
TH3_k127_7478395_19	1403819.BATR01000098_gene3285	1.565e-67	232.0	COG1917@1|root,COG1917@2|Bacteria,46WE0@74201|Verrucomicrobia,2IVZR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TH3_k127_7478395_0	240016.ABIZ01000001_gene2256	0.0	1293.0	COG1413@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,46XAM@74201|Verrucomicrobia,2IV7A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,ThuA
TH3_k127_7478395_7	497964.CfE428DRAFT_3584	7.654e-174	554.0	COG5441@1|root,COG5441@2|Bacteria,46U7U@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
TH3_k127_7478395_18	411473.RUMCAL_02004	2.069e-75	272.0	COG5492@1|root,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,24A7I@186801|Clostridia,3WGX5@541000|Ruminococcaceae	186801|Clostridia	N	dockerin type I repeat-containing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
TH3_k127_7478395_9	768706.Desor_3179	9.734e-156	523.0	COG5492@1|root,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,24A7I@186801|Clostridia,262NZ@186807|Peptococcaceae	186801|Clostridia	N	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,LRR_5
TH3_k127_7478395_16	1121012.AUKX01000016_gene3000	1.06e-95	329.0	28K60@1|root,2Z9UH@2|Bacteria,4NHE6@976|Bacteroidetes,1HYIC@117743|Flavobacteriia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
TH3_k127_7478395_6	1121012.AUKX01000016_gene3001	1.857e-179	574.0	COG0673@1|root,COG0673@2|Bacteria,4NGTW@976|Bacteroidetes,1I164@117743|Flavobacteriia,23IAD@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_7478395_20	485917.Phep_3119	2.156e-65	234.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,4NG20@976|Bacteroidetes,1J03Z@117747|Sphingobacteriia	976|Bacteroidetes	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
TH3_k127_7478395_15	1396141.BATP01000028_gene2285	2.116e-99	363.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
TH3_k127_7478395_28	1303518.CCALI_01975	4.221e-13	73.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_7493055_0	251221.35214444	9.805e-217	695.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	dpp4	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
TH3_k127_7493055_4	497964.CfE428DRAFT_0725	5.004e-36	149.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
TH3_k127_7493055_1	1122605.KB893625_gene1683	9.523e-206	658.0	COG1501@1|root,COG1501@2|Bacteria,4PKHN@976|Bacteroidetes,1IP35@117747|Sphingobacteriia	976|Bacteroidetes	G	He_PIG associated, NEW1 domain of bacterial glycohydrolase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	He_PIG,He_PIG_assoc,Melibiase_2,NPCBM
TH3_k127_7493055_5	935839.JAGJ01000024_gene2469	5.605e-26	124.0	COG0737@1|root,COG3250@1|root,COG3934@1|root,COG4409@1|root,COG0737@2|Bacteria,COG3250@2|Bacteria,COG3934@2|Bacteria,COG4409@2|Bacteria,2I0CJ@201174|Actinobacteria	201174|Actinobacteria	G	BNR Asp-box repeat	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,DUF4091,F5_F8_type_C,NPCBM,NPCBM_assoc
TH3_k127_7493055_3	1122915.AUGY01000073_gene4393	5.649e-39	164.0	COG4030@1|root,COG4030@2|Bacteria,1TRZY@1239|Firmicutes,4IT8Q@91061|Bacilli,277AM@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
TH3_k127_7493055_6	1303518.CCALI_02493	9.535e-09	66.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_7493055_2	1089553.Tph_c09100	4.801e-98	338.0	COG0407@1|root,COG0407@2|Bacteria,1TRJG@1239|Firmicutes,24B34@186801|Clostridia,42G9W@68295|Thermoanaerobacterales	186801|Clostridia	H	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
TH3_k127_7493055_8	1089553.Tph_c09110	0.0002461	53.0	2CJTW@1|root,33NBH@2|Bacteria,1VM99@1239|Firmicutes,24UVS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7493055_7	1396141.BATP01000057_gene3096	7.727e-05	54.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	CHU_C,Cadherin,F5_F8_type_C,Laminin_G_3
TH3_k127_7493668_0	314230.DSM3645_26609	2.063e-248	813.0	COG2010@1|root,COG2133@1|root,COG3828@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IYH1@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Cytochrom_C,Cytochrome_CBB3,Laminin_G_3,ThuA
TH3_k127_7493668_3	290397.Adeh_2327	3.118e-20	106.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,42M86@68525|delta/epsilon subdivisions,2WIT1@28221|Deltaproteobacteria,2YYIV@29|Myxococcales	28221|Deltaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
TH3_k127_7493668_4	1158292.JPOE01000002_gene3555	1.059e-07	57.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
TH3_k127_7493668_2	443143.GM18_2869	4.022e-41	152.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,42M86@68525|delta/epsilon subdivisions,2WIT1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
TH3_k127_7493668_1	794903.OPIT5_07655	3.994e-77	269.0	COG1700@1|root,COG1700@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09124	-	-	-	-	ko00000	-	-	-	DUF2357,PDDEXK_7
TH3_k127_7496640_0	509191.AEDB02000002_gene1137	1.309e-118	413.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TH3_k127_7496640_2	316274.Haur_0034	1.439e-41	161.0	COG2968@1|root,COG2968@2|Bacteria	2|Bacteria	S	cellular response to heat	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
TH3_k127_7496640_3	697282.Mettu_1883	7.716e-06	56.0	2DEM1@1|root,2ZNEB@2|Bacteria,1P8KJ@1224|Proteobacteria,1SVJ0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7496640_1	497964.CfE428DRAFT_3809	5.391e-53	194.0	COG0330@1|root,COG0330@2|Bacteria,46VZD@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TH3_k127_7516828_1	497964.CfE428DRAFT_6615	5.694e-106	349.0	COG1902@1|root,COG1902@2|Bacteria	2|Bacteria	C	pentaerythritol trinitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Oxidored_FMN
TH3_k127_7516828_6	452637.Oter_0903	1.166e-22	102.0	COG1917@1|root,COG1917@2|Bacteria,46WMQ@74201|Verrucomicrobia,3K8IQ@414999|Opitutae	414999|Opitutae	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TH3_k127_7516828_2	497964.CfE428DRAFT_0298	4.46e-61	220.0	COG2258@1|root,COG2258@2|Bacteria,46VBP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7516828_3	382464.ABSI01000020_gene153	8.659e-45	171.0	COG2194@1|root,COG2194@2|Bacteria,46XHR@74201|Verrucomicrobia,2IVYD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7516828_5	1121957.ATVL01000007_gene2357	1.155e-37	158.0	COG4330@1|root,COG4330@2|Bacteria,4NNT4@976|Bacteroidetes,47PCZ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
TH3_k127_7516828_4	269798.CHU_1304	7.265e-41	166.0	2AQME@1|root,31FUG@2|Bacteria,4NRV3@976|Bacteroidetes,47VCI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7516828_7	1123508.JH636439_gene568	5.004e-20	106.0	COG0526@1|root,COG1413@1|root,COG0526@2|Bacteria,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
TH3_k127_7516828_0	497964.CfE428DRAFT_0876	1.584e-122	399.0	COG0825@1|root,COG0825@2|Bacteria,46SE1@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
TH3_k127_7519104_1	153721.MYP_3371	1.363e-19	94.0	2DEAY@1|root,32U31@2|Bacteria,4NU2N@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7519104_0	1123242.JH636434_gene4912	6.762e-131	434.0	COG1053@1|root,COG1053@2|Bacteria,2J3SP@203682|Planctomycetes	203682|Planctomycetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
TH3_k127_7526108_10	396588.Tgr7_2069	6.407e-25	107.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1WW5P@135613|Chromatiales	135613|Chromatiales	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
TH3_k127_7526108_13	315456.RF_0905	2.56e-13	77.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2UD3W@28211|Alphaproteobacteria,47FG2@766|Rickettsiales	766|Rickettsiales	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
TH3_k127_7526108_6	1382356.JQMP01000004_gene475	5.839e-74	259.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,27XI5@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	-	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
TH3_k127_7526108_1	583355.Caka_3065	6.934e-105	365.0	COG0768@1|root,COG0768@2|Bacteria,46SEZ@74201|Verrucomicrobia,3K799@414999|Opitutae	414999|Opitutae	M	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
TH3_k127_7526108_9	1121472.AQWN01000001_gene239	2.161e-41	164.0	COG2859@1|root,COG2859@2|Bacteria,1V1Q4@1239|Firmicutes,24GEE@186801|Clostridia,264GJ@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
TH3_k127_7526108_3	497964.CfE428DRAFT_2938	4.256e-93	322.0	COG0770@1|root,COG0770@2|Bacteria,46SDF@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TH3_k127_7526108_2	794903.OPIT5_03555	2.54e-104	351.0	COG0472@1|root,COG0472@2|Bacteria,46SD0@74201|Verrucomicrobia,3K7EK@414999|Opitutae	414999|Opitutae	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
TH3_k127_7526108_12	1408422.JHYF01000017_gene1849	7.868e-19	95.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes	1239|Firmicutes	M	PFAM LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
TH3_k127_7526108_7	497964.CfE428DRAFT_2934	1.073e-73	262.0	COG0772@1|root,COG0772@2|Bacteria,46SMC@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
TH3_k127_7526108_8	497964.CfE428DRAFT_2933	5.031e-66	243.0	COG0707@1|root,COG0707@2|Bacteria,46S84@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
TH3_k127_7526108_4	1156937.MFUM_1050006	3.262e-87	299.0	COG0773@1|root,COG0812@1|root,COG0773@2|Bacteria,COG0812@2|Bacteria,46SCG@74201|Verrucomicrobia,37G48@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Mur ligase family, catalytic domain	murB	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4,MurB_C,Mur_ligase,Mur_ligase_C,Mur_ligase_M
TH3_k127_7526108_5	478741.JAFS01000001_gene1134	2.381e-78	273.0	COG1181@1|root,COG1181@2|Bacteria,46UZ2@74201|Verrucomicrobia,37GF6@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
TH3_k127_7526108_14	96561.Dole_2784	2.575e-10	71.0	COG1589@1|root,COG1589@2|Bacteria,1RDX7@1224|Proteobacteria,42VCZ@68525|delta/epsilon subdivisions,2WRVM@28221|Deltaproteobacteria,2MKM3@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Essential cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
TH3_k127_7526108_0	497964.CfE428DRAFT_2928	1.181e-108	367.0	COG0849@1|root,COG0849@2|Bacteria,46SQI@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
TH3_k127_7526108_11	545696.HOLDEFILI_01767	3.78e-23	113.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,3VNTG@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
TH3_k127_7545074_0	861299.J421_1753	1.74e-216	704.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
TH3_k127_7545074_6	530564.Psta_1182	1.213e-53	198.0	COG1262@1|root,COG1262@2|Bacteria,2IZ7E@203682|Planctomycetes	203682|Planctomycetes	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TH3_k127_7545074_5	335543.Sfum_1623	1.766e-59	230.0	COG3118@1|root,COG3118@2|Bacteria,1PQ8G@1224|Proteobacteria	1224|Proteobacteria	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
TH3_k127_7545074_11	324057.Pjdr2_1173	8.086e-06	60.0	COG3664@1|root,COG5434@1|root,COG5520@1|root,COG3664@2|Bacteria,COG5434@2|Bacteria,COG5520@2|Bacteria,1VC96@1239|Firmicutes,4HV2Q@91061|Bacilli,2774T@186822|Paenibacillaceae	91061|Bacilli	M	S-layer homology domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Big_4,CBM9_1,Pectate_lyase_3,SLH
TH3_k127_7545074_14	979556.MTES_1035	0.0001665	56.0	COG3664@1|root,COG3664@2|Bacteria,2IAP4@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_cc
TH3_k127_7545074_13	278957.ABEA03000117_gene1086	0.0001264	56.0	COG3664@1|root,COG3664@2|Bacteria,46XQU@74201|Verrucomicrobia,3K962@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7545074_12	1340493.JNIF01000003_gene2695	1.781e-05	51.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7545074_10	1340493.JNIF01000003_gene2695	7.105e-08	62.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7545074_9	1227352.C173_18071	1.126e-12	72.0	COG0697@1|root,COG0697@2|Bacteria,1VP2K@1239|Firmicutes,4I1UM@91061|Bacilli,26WQN@186822|Paenibacillaceae	91061|Bacilli	EG	Protein of unknown function (DUF2569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2569
TH3_k127_7545074_8	1303518.CCALI_01840	6.904e-13	79.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_7545074_7	1403819.BATR01000164_gene5643	1.173e-16	95.0	COG2010@1|root,COG2010@2|Bacteria,46V0R@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
TH3_k127_7545074_4	797209.ZOD2009_14571	3.158e-67	257.0	COG1621@1|root,arCOG08134@2157|Archaea,2XUXA@28890|Euryarchaeota,23UA6@183963|Halobacteria	183963|Halobacteria	G	COG1621 Beta-fructosidases (levanase invertase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
TH3_k127_7545074_2	344747.PM8797T_11379	4.532e-130	423.0	COG1879@1|root,COG1879@2|Bacteria,2IYMH@203682|Planctomycetes	203682|Planctomycetes	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
TH3_k127_7545074_1	344747.PM8797T_11384	4.234e-188	599.0	COG1129@1|root,COG1129@2|Bacteria,2IWTU@203682|Planctomycetes	2|Bacteria	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA_3	-	3.6.3.17	ko:K10441,ko:K17210	ko02010,map02010	M00212,M00592	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.21	-	-	ABC_tran
TH3_k127_7545681_5	497964.CfE428DRAFT_2915	8.035e-95	318.0	COG0541@1|root,COG0541@2|Bacteria,46SIU@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
TH3_k127_7545681_16	1499967.BAYZ01000080_gene944	1.524e-20	104.0	2DM1D@1|root,31AEB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7545681_11	1125701.HMPREF1221_01616	3.618e-45	184.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7545681_12	324057.Pjdr2_0886	2.512e-39	158.0	COG1470@1|root,COG3210@1|root,COG4447@1|root,COG4932@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4447@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,CHB_HEX_C_1,Cadherin-like,Flg_new,SLH,fn3
TH3_k127_7545681_14	1198452.Jab_1c17570	1.473e-26	116.0	2DP2V@1|root,330AH@2|Bacteria,1R3EE@1224|Proteobacteria,2WFSH@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3455
TH3_k127_7545681_19	404589.Anae109_2405	6.13e-10	66.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
TH3_k127_7545681_20	404589.Anae109_2405	9.387e-05	55.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
TH3_k127_7545681_15	1123020.AUIE01000005_gene4447	4.238e-25	108.0	COG0346@1|root,COG0346@2|Bacteria,1RHZT@1224|Proteobacteria,1S679@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
TH3_k127_7545681_3	1123023.JIAI01000001_gene6305	4.006e-119	388.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	-	-	-	-	-	-	-	-	-	CMAS,Methyltransf_25
TH3_k127_7545681_1	1403819.BATR01000020_gene698	4.424e-190	640.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
TH3_k127_7545681_13	1396141.BATP01000060_gene4559	4.188e-34	146.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
TH3_k127_7545681_9	497964.CfE428DRAFT_4864	5.459e-64	228.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7545681_2	314230.DSM3645_23076	5.795e-123	411.0	COG1520@1|root,COG1520@2|Bacteria,2IXN8@203682|Planctomycetes	203682|Planctomycetes	S	serine threonine protein kinase afsK	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
TH3_k127_7545681_10	497964.CfE428DRAFT_0226	1.547e-50	185.0	COG0663@1|root,COG0663@2|Bacteria	2|Bacteria	G	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
TH3_k127_7545681_6	204669.Acid345_1044	1.645e-92	313.0	COG2220@1|root,COG2220@2|Bacteria,3Y2TV@57723|Acidobacteria,2JHT8@204432|Acidobacteriia	204432|Acidobacteriia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
TH3_k127_7545681_7	278963.ATWD01000001_gene3347	2.392e-85	298.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,F5_F8_type_C,Pectate_lyase_3
TH3_k127_7545681_8	1122917.KB899670_gene4247	4.053e-77	290.0	COG0457@1|root,COG0457@2|Bacteria,1TPP8@1239|Firmicutes,4HCXY@91061|Bacilli,26S7B@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF5107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5107,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
TH3_k127_7545681_0	661478.OP10G_0633	4.05e-268	834.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
TH3_k127_7545681_17	1304885.AUEY01000005_gene869	7.323e-15	76.0	2DR98@1|root,33ARN@2|Bacteria,1NHFU@1224|Proteobacteria,42X3T@68525|delta/epsilon subdivisions,2WSSX@28221|Deltaproteobacteria,2MMBR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
TH3_k127_7545681_18	161156.JQKW01000008_gene436	2.768e-13	75.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K19093	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
TH3_k127_7545681_4	671143.DAMO_2856	7.3e-101	336.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
TH3_k127_7545811_1	861299.J421_0969	3.937e-189	605.0	COG3119@1|root,COG3119@2|Bacteria,1ZUXF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TH3_k127_7545811_2	1403819.BATR01000133_gene4740	6.728e-178	598.0	COG3540@1|root,COG3540@2|Bacteria,46XER@74201|Verrucomicrobia,2IVPT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7545811_0	497964.CfE428DRAFT_4754	8.268e-192	639.0	COG3119@1|root,COG3119@2|Bacteria,46UET@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
TH3_k127_7545811_7	395961.Cyan7425_0454	6.303e-13	70.0	COG3153@1|root,COG3153@2|Bacteria,1GK4X@1117|Cyanobacteria,3KIFY@43988|Cyanothece	1117|Cyanobacteria	S	PFAM GCN5-related N-acetyltransferase	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_9
TH3_k127_7545811_6	296591.Bpro_2383	8.629e-16	85.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,2VXVS@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TH3_k127_7545811_5	794903.OPIT5_11625	3.013e-61	220.0	COG1451@1|root,COG1451@2|Bacteria,46VW6@74201|Verrucomicrobia,3K7I9@414999|Opitutae	414999|Opitutae	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
TH3_k127_7545811_4	264732.Moth_2023	7.897e-63	245.0	COG2017@1|root,COG2017@2|Bacteria	2|Bacteria	G	converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim,DUF4380
TH3_k127_7545811_3	1089547.KB913013_gene868	9.971e-96	346.0	COG3934@1|root,COG3934@2|Bacteria,4NGQC@976|Bacteroidetes,47M9B@768503|Cytophagia	976|Bacteroidetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_2_C
TH3_k127_7545811_8	661478.OP10G_3387	1.309e-12	82.0	COG3250@1|root,COG3387@1|root,COG3250@2|Bacteria,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1793,DUF4964,DUF4965,DUF5127,RicinB_lectin_2
TH3_k127_7552397_0	693746.OBV_03580	1.139e-52	195.0	COG1404@1|root,COG1404@2|Bacteria,1VD5C@1239|Firmicutes,24C2E@186801|Clostridia,2N8J1@216572|Oscillospiraceae	186801|Clostridia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TH3_k127_7552397_3	240016.ABIZ01000001_gene3530	1.342e-30	135.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,46TNN@74201|Verrucomicrobia,2ITZ4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
TH3_k127_7552397_6	278963.ATWD01000001_gene1092	3.137e-11	77.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
TH3_k127_7552397_5	1303518.CCALI_01585	1.618e-19	90.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
TH3_k127_7552397_2	518766.Rmar_1378	2.358e-32	134.0	COG0526@1|root,COG0526@2|Bacteria,4NI00@976|Bacteroidetes	976|Bacteroidetes	CO	Pfam AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
TH3_k127_7552397_1	1396141.BATP01000022_gene383	1.459e-41	175.0	COG1595@1|root,COG1595@2|Bacteria,46TQ4@74201|Verrucomicrobia,2IVYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4
TH3_k127_7552397_7	555779.Dthio_PD0141	5.951e-07	61.0	COG0438@1|root,COG1215@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,1MU5I@1224|Proteobacteria	1224|Proteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TH3_k127_7552397_4	189425.PGRAT_08230	1.148e-21	108.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HAGN@91061|Bacilli,271NY@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.361	ko:K18652	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_7555768_1	1122986.KB908329_gene2419	2.167e-54	214.0	COG5652@1|root,COG5652@2|Bacteria,4NIE7@976|Bacteroidetes,2FQJV@200643|Bacteroidia	976|Bacteroidetes	S	Heparinase II/III-like protein	-	GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008201,GO:0009056,GO:0009057,GO:0009987,GO:0016829,GO:0016835,GO:0016837,GO:0030202,GO:0030203,GO:0030211,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044464,GO:0047488,GO:0071704,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901681,GO:1903510	4.2.2.7,4.2.2.8	ko:K19051	-	-	-	-	ko00000,ko01000	-	PL21	-	DUF4962,Hepar_II_III
TH3_k127_7581675_3	589865.DaAHT2_0949	1.529e-18	89.0	COG0296@1|root,COG0296@2|Bacteria,1NIZI@1224|Proteobacteria,42WYM@68525|delta/epsilon subdivisions,2WSNX@28221|Deltaproteobacteria,2MMER@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
TH3_k127_7581675_6	106370.Francci3_3071	5.437e-06	53.0	COG2104@1|root,COG2104@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	iJN678.ycf40	ThiS
TH3_k127_7581675_4	330214.NIDE4027	7.203e-11	70.0	COG1076@1|root,COG1076@2|Bacteria,3J1CS@40117|Nitrospirae	40117|Nitrospirae	O	DnaJ molecular chaperone homology domain	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	-
TH3_k127_7581675_2	497964.CfE428DRAFT_1749	1.921e-46	171.0	COG0316@1|root,COG0316@2|Bacteria,46T1T@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
TH3_k127_7581675_5	682795.AciX8_1050	2.364e-06	59.0	2C730@1|root,32UQY@2|Bacteria,3Y59Z@57723|Acidobacteria,2JJP2@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7581675_1	1185876.BN8_00813	2.48e-108	358.0	COG2220@1|root,COG2220@2|Bacteria,4PJJ0@976|Bacteroidetes,47NNW@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
TH3_k127_7581675_0	1396418.BATQ01000078_gene592	9.309e-117	381.0	COG0620@1|root,COG0620@2|Bacteria,46W8R@74201|Verrucomicrobia,2IWM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cobalamin-independent synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
TH3_k127_7589901_0	243090.RB700	0.0	1030.0	COG3408@1|root,COG3408@2|Bacteria,2J2NJ@203682|Planctomycetes	203682|Planctomycetes	G	Alpha-L-rhamnosidase N-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
TH3_k127_7589901_1	158190.SpiGrapes_2868	2.835e-06	58.0	2DPDH@1|root,331MF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7593280_4	497964.CfE428DRAFT_5017	4.285e-63	224.0	COG1354@1|root,COG1354@2|Bacteria,46UBD@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	-	-	-	-	-	-	-	-	-	SMC_ScpA
TH3_k127_7593280_9	330214.NIDE1418	1.067e-38	153.0	COG1386@1|root,COG1386@2|Bacteria,3J15Z@40117|Nitrospirae	40117|Nitrospirae	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
TH3_k127_7593280_11	317936.Nos7107_2700	2.337e-16	84.0	COG3577@1|root,COG3577@2|Bacteria	2|Bacteria	S	aspartic-type endopeptidase activity	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	Asp_protease_2,gag-asp_proteas
TH3_k127_7593280_8	1122918.KB907245_gene5077	1.881e-39	154.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,26UCZ@186822|Paenibacillaceae	91061|Bacilli	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
TH3_k127_7593280_7	452637.Oter_1044	1.637e-42	160.0	COG1397@1|root,COG1397@2|Bacteria,46VZX@74201|Verrucomicrobia	74201|Verrucomicrobia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7593280_5	997346.HMPREF9374_2103	7.417e-61	219.0	COG5113@1|root,COG3236@2|Bacteria,1V7IA@1239|Firmicutes,4HK8U@91061|Bacilli,27C7F@186824|Thermoactinomycetaceae	91061|Bacilli	O	Domain of unknown function (DUF1768)	ybiA	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
TH3_k127_7593280_2	497964.CfE428DRAFT_1977	8.998e-114	370.0	COG1051@1|root,COG1051@2|Bacteria,46SHC@74201|Verrucomicrobia	74201|Verrucomicrobia	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
TH3_k127_7593280_0	497964.CfE428DRAFT_1982	5.618e-149	484.0	COG0330@1|root,COG0330@2|Bacteria,46U2V@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TH3_k127_7593280_1	497964.CfE428DRAFT_1983	7.263e-123	404.0	COG0061@1|root,COG0061@2|Bacteria,46UHQ@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7593280_3	497964.CfE428DRAFT_1980	7.639e-88	302.0	COG4295@1|root,COG4295@2|Bacteria,46TDT@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Uncharacterized protein conserved in bacteria (DUF2263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2263
TH3_k127_7593280_10	1210884.HG799465_gene11759	5.583e-27	115.0	2BRR1@1|root,32KQS@2|Bacteria,2J4RN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7593280_6	497964.CfE428DRAFT_1981	2.044e-53	194.0	COG1397@1|root,COG1397@2|Bacteria	2|Bacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
TH3_k127_7594005_7	1521187.JPIM01000012_gene1633	3.038e-13	72.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi,375F5@32061|Chloroflexia	32061|Chloroflexia	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
TH3_k127_7594005_5	497964.CfE428DRAFT_4578	1.549e-37	146.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsN3	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
TH3_k127_7594005_0	497964.CfE428DRAFT_4579	1.09e-218	693.0	COG0018@1|root,COG0018@2|Bacteria,46SH6@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
TH3_k127_7594005_1	583355.Caka_0776	3.68e-143	460.0	COG0714@1|root,COG0714@2|Bacteria,46SC8@74201|Verrucomicrobia,3K7W0@414999|Opitutae	414999|Opitutae	S	PFAM ATPase associated with various cellular activities AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TH3_k127_7594005_6	240015.ACP_0051	7.958e-15	78.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
TH3_k127_7594005_2	1167006.UWK_00745	2.667e-83	287.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2WK1X@28221|Deltaproteobacteria,2MJBE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TH3_k127_7594005_3	583355.Caka_0779	3.457e-79	278.0	COG2304@1|root,COG2304@2|Bacteria,46SKE@74201|Verrucomicrobia,3K7H6@414999|Opitutae	414999|Opitutae	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
TH3_k127_7594005_4	1167006.UWK_00742	2.24e-71	254.0	COG0457@1|root,COG2304@1|root,COG5414@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,COG5414@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_16,TPR_2,VWA,VWA_2
TH3_k127_7595407_1	497964.CfE428DRAFT_1032	1.305e-169	550.0	COG3170@1|root,COG3170@2|Bacteria,46W02@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7595407_0	661478.OP10G_4223	4.656e-198	645.0	COG3754@1|root,COG3754@2|Bacteria	2|Bacteria	M	Rhamnan synthesis protein F	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WbsX,RgpF
TH3_k127_7595407_2	471854.Dfer_2296	6.173e-110	386.0	COG2152@1|root,COG2152@2|Bacteria,4P1IV@976|Bacteroidetes	976|Bacteroidetes	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7595407_5	243090.RB4769	2.618e-12	78.0	28MMN@1|root,2ZAXE@2|Bacteria,2IY1P@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7595407_4	575540.Isop_2194	1.869e-31	136.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	3.4.13.22	ko:K08641,ko:K11206	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	CN_hydrolase,Peptidase_M15
TH3_k127_7595407_3	1121403.AUCV01000014_gene4604	4.352e-90	308.0	COG3420@1|root,COG3420@2|Bacteria,1NIRV@1224|Proteobacteria	1224|Proteobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TH3_k127_760890_1	395493.BegalDRAFT_2935	5.147e-79	274.0	COG1408@1|root,COG1408@2|Bacteria,1RK37@1224|Proteobacteria,1SEEW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolase activity	yaeI	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
TH3_k127_760890_0	497964.CfE428DRAFT_1577	5.423e-157	504.0	COG0502@1|root,COG0502@2|Bacteria,46SFX@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Biotin and Thiamin Synthesis associated domain	-	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
TH3_k127_760890_2	1396141.BATP01000003_gene4967	8.104e-67	238.0	COG3391@1|root,COG3391@2|Bacteria,46X7X@74201|Verrucomicrobia,2IUXV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
TH3_k127_7629841_0	1156937.MFUM_270006	6.863e-86	288.0	COG1154@1|root,COG1154@2|Bacteria,46SAU@74201|Verrucomicrobia,37G36@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
TH3_k127_7629841_2	794903.OPIT5_17250	1.174e-13	74.0	COG1722@1|root,COG1722@2|Bacteria,46TB2@74201|Verrucomicrobia,3K8ES@414999|Opitutae	414999|Opitutae	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
TH3_k127_7629841_3	278957.ABEA03000201_gene4321	0.0001665	53.0	COG1450@1|root,COG1450@2|Bacteria,46UJF@74201|Verrucomicrobia,3K7CH@414999|Opitutae	414999|Opitutae	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
TH3_k127_7629841_1	675806.VII_002989	4.858e-43	167.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1XSYD@135623|Vibrionales	135623|Vibrionales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
TH3_k127_7637832_9	382464.ABSI01000012_gene2160	1.043e-54	202.0	COG2831@1|root,COG2831@2|Bacteria,46TZZ@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
TH3_k127_7637832_7	452637.Oter_1611	3.354e-109	364.0	COG1477@1|root,COG1477@2|Bacteria,46V6N@74201|Verrucomicrobia,3K9VB@414999|Opitutae	414999|Opitutae	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
TH3_k127_7637832_14	452637.Oter_1612	2.247e-38	150.0	COG0526@1|root,COG0526@2|Bacteria,46W0W@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
TH3_k127_7637832_16	452637.Oter_1613	8.89e-19	87.0	2BFNH@1|root,329GX@2|Bacteria,46WJ5@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
TH3_k127_7637832_4	933262.AXAM01000098_gene3457	7.732e-124	416.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WMS6@28221|Deltaproteobacteria,2MNJX@213118|Desulfobacterales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
TH3_k127_7637832_10	1121920.AUAU01000009_gene1881	4.296e-52	212.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
TH3_k127_7637832_8	247634.GPB2148_909	2.328e-76	267.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,1RQT8@1236|Gammaproteobacteria,1J6J9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Microcin C7 resistance	ldcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009050,GO:0009056,GO:0009254,GO:0009987,GO:0016787,GO:0019538,GO:0030203,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	iAPECO1_1312.APECO1_304,iECABU_c1320.ECABU_c14580,iECED1_1282.ECED1_1334,iECOK1_1307.ECOK1_1338,iECS88_1305.ECS88_1255,iLF82_1304.LF82_1171,iNRG857_1313.NRG857_06085,iSFV_1184.SFV_1201,iSFxv_1172.SFxv_1357,iS_1188.S1271,iUMN146_1321.UM146_11125,iUTI89_1310.UTI89_C1378,ic_1306.c1641	Peptidase_S66
TH3_k127_7637832_17	661478.OP10G_2992	3.044e-13	79.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_7637832_0	118168.MC7420_4981	1.308e-186	613.0	COG0642@1|root,COG2202@1|root,COG4251@1|root,COG0642@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1G09B@1117|Cyanobacteria,1H82F@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GAF,GAF_3,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TH3_k127_7637832_11	1121441.AUCX01000016_gene2382	1.256e-42	180.0	COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,42RTP@68525|delta/epsilon subdivisions,2WN9M@28221|Deltaproteobacteria,2M9XH@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_8,Response_reg,SpoIIE
TH3_k127_7637832_1	240016.ABIZ01000001_gene2661	1.831e-171	543.0	COG0031@1|root,COG0031@2|Bacteria,46W12@74201|Verrucomicrobia,2IWMW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TH3_k127_7637832_5	344747.PM8797T_00347	3.063e-123	407.0	COG1158@1|root,COG1158@2|Bacteria,2IXBX@203682|Planctomycetes	203682|Planctomycetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
TH3_k127_7637832_2	644968.DFW101_0541	8.14e-171	554.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,2M8UV@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
TH3_k127_7637832_12	443143.GM18_1309	5.207e-40	156.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
TH3_k127_7637832_3	756499.Desde_1902	3.68e-165	536.0	COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia	186801|Clostridia	E	Aminotransferase	-	-	2.6.1.37	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R04152	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
TH3_k127_7637832_13	321332.CYB_1025	1.051e-38	147.0	COG0607@1|root,COG0607@2|Bacteria,1GPXG@1117|Cyanobacteria,1H0XW@1129|Synechococcus	1117|Cyanobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TH3_k127_7637832_15	530564.Psta_0575	3.291e-37	145.0	COG0662@1|root,COG0662@2|Bacteria,2J4Q9@203682|Planctomycetes	203682|Planctomycetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TH3_k127_7637832_6	761193.Runsl_5537	3.386e-113	374.0	COG2382@1|root,COG3386@1|root,COG2382@2|Bacteria,COG3386@2|Bacteria,4NK15@976|Bacteroidetes,47MMH@768503|Cytophagia	976|Bacteroidetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,SGL
TH3_k127_7659438_0	886293.Sinac_6968	8.88e-232	737.0	COG4654@1|root,COG4654@2|Bacteria,2IX0M@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
TH3_k127_7659438_1	1123508.JH636439_gene1235	2.027e-222	696.0	COG3119@1|root,COG3119@2|Bacteria,2IXQ5@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TH3_k127_7679576_7	583355.Caka_2284	3.716e-15	78.0	COG0204@1|root,COG0204@2|Bacteria,46SYR@74201|Verrucomicrobia,3K7W9@414999|Opitutae	414999|Opitutae	I	Glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TH3_k127_7679576_1	925409.KI911562_gene2080	7.191e-148	482.0	COG0673@1|root,COG0673@2|Bacteria,4NF96@976|Bacteroidetes,1IX0E@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_7679576_6	497964.CfE428DRAFT_4596	5.462e-21	109.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K02283,ko:K02454,ko:K03220,ko:K03466	ko03070,ko05111,map03070,map05111	M00331,M00332	-	-	ko00000,ko00001,ko00002,ko02035,ko02044,ko03036	3.A.12,3.A.15,3.A.6.1	-	-	Cytochrom_c3_2,FHA,FtsK_SpoIIIE,Response_reg,T2SSE,Yop-YscD_cpl,Yop-YscD_ppl
TH3_k127_7679576_5	497964.CfE428DRAFT_5353	1.5e-22	115.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
TH3_k127_7679576_3	382464.ABSI01000013_gene1773	3.512e-31	139.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7679576_8	1118153.MOY_06927	3.816e-05	53.0	COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1S7JH@1236|Gammaproteobacteria,1XKGS@135619|Oceanospirillales	135619|Oceanospirillales	NU	Type IV Pilus-assembly protein W	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,PilW
TH3_k127_7679576_4	909663.KI867150_gene972	6.979e-31	124.0	2CIE9@1|root,32S7U@2|Bacteria,1P112@1224|Proteobacteria,431TX@68525|delta/epsilon subdivisions,2WWP3@28221|Deltaproteobacteria,2MS3R@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4404)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4404
TH3_k127_7679576_2	497964.CfE428DRAFT_5925	5.167e-57	208.0	COG0125@1|root,COG0125@2|Bacteria,46ST1@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
TH3_k127_7679576_0	497964.CfE428DRAFT_4166	1.84e-153	499.0	COG0215@1|root,COG0215@2|Bacteria,46SES@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
TH3_k127_7717228_1	497964.CfE428DRAFT_6615	3.369e-127	413.0	COG1902@1|root,COG1902@2|Bacteria	2|Bacteria	C	pentaerythritol trinitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Oxidored_FMN
TH3_k127_7717228_0	530564.Psta_1454	1.905e-139	447.0	COG0274@1|root,COG0274@2|Bacteria,2IWY0@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
TH3_k127_7717228_2	313612.L8106_06989	1.557e-20	97.0	COG2337@1|root,COG2337@2|Bacteria,1G72T@1117|Cyanobacteria,1HDXS@1150|Oscillatoriales	1117|Cyanobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
TH3_k127_7717228_3	530564.Psta_1454	3.656e-14	73.0	COG0274@1|root,COG0274@2|Bacteria,2IWY0@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
TH3_k127_7717228_4	471854.Dfer_4066	1.014e-07	55.0	COG0673@1|root,COG0673@2|Bacteria,4NF9M@976|Bacteroidetes,47JCP@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
TH3_k127_7718269_2	1396141.BATP01000060_gene4560	9.618e-22	112.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
TH3_k127_7718269_0	7668.SPU_001163-tr	9.954e-77	291.0	COG0666@1|root,KOG0504@2759|Eukaryota,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3BGGV@33208|Metazoa,3CT1S@33213|Bilateria	33208|Metazoa	M	ankyrin 3, node of Ranvier (ankyrin G)	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,ZU5
TH3_k127_7718269_3	583355.Caka_1010	1e-05	60.0	COG0790@1|root,COG4775@1|root,COG0790@2|Bacteria,COG4775@2|Bacteria,46W4W@74201|Verrucomicrobia,3K9YE@414999|Opitutae	414999|Opitutae	M	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
TH3_k127_7718269_1	481448.Minf_0292	3.168e-39	170.0	COG0760@1|root,COG0760@2|Bacteria,46SU4@74201|Verrucomicrobia,37G1D@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
TH3_k127_7749726_61	717606.PaecuDRAFT_2033	1.032e-49	194.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
TH3_k127_7749726_85	243090.RB10666	7.894e-21	109.0	COG1361@1|root,COG1361@2|Bacteria,2IYS8@203682|Planctomycetes	203682|Planctomycetes	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
TH3_k127_7749726_68	331678.Cphamn1_2540	1.817e-42	158.0	2DNV7@1|root,32ZAW@2|Bacteria	2|Bacteria	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
TH3_k127_7749726_2	497964.CfE428DRAFT_2396	8.08e-297	924.0	COG0441@1|root,COG0441@2|Bacteria,46S5A@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
TH3_k127_7749726_95	1321774.HMPREF9108_01413	2.048e-09	66.0	COG0515@1|root,COG0515@2|Bacteria,37AZU@32066|Fusobacteria	32066|Fusobacteria	KLT	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DKNYY
TH3_k127_7749726_89	1333856.L686_13365	2.883e-14	79.0	COG0515@1|root,COG0515@2|Bacteria,1NCFW@1224|Proteobacteria	1224|Proteobacteria	KLT	DKNYY family	-	-	-	-	-	-	-	-	-	-	-	-	DKNYY
TH3_k127_7749726_74	497964.CfE428DRAFT_2396	4.052e-34	134.0	COG0441@1|root,COG0441@2|Bacteria,46S5A@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
TH3_k127_7749726_3	497964.CfE428DRAFT_6515	1.02e-296	973.0	COG0457@1|root,COG0457@2|Bacteria,46UKC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	FAT,Peptidase_C39_2
TH3_k127_7749726_51	452637.Oter_0107	5.822e-61	222.0	COG2761@1|root,COG2761@2|Bacteria	2|Bacteria	Q	protein disulfide oxidoreductase activity	frnE	-	-	-	-	-	-	-	-	-	-	-	DSBA
TH3_k127_7749726_26	526224.Bmur_0878	1.257e-114	378.0	COG0616@1|root,COG0616@2|Bacteria,2J9E9@203691|Spirochaetes	203691|Spirochaetes	OU	Serine dehydrogenase proteinase	-	-	-	-	-	-	-	-	-	-	-	-	SDH_sah
TH3_k127_7749726_92	452637.Oter_2236	6.586e-12	66.0	COG4877@1|root,COG4877@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
TH3_k127_7749726_32	452637.Oter_2237	1.821e-101	340.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	f42a	-	-	-	-	-	-	-	-	-	-	-	Band_7
TH3_k127_7749726_1	1396141.BATP01000030_gene3783	1.489e-313	976.0	28I74@1|root,2Z8A0@2|Bacteria,46TG0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	COG NOG26804 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7749726_81	635013.TherJR_1799	1.891e-26	116.0	COG4262@1|root,COG4262@2|Bacteria,1UYRF@1239|Firmicutes,24AHS@186801|Clostridia	186801|Clostridia	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
TH3_k127_7749726_56	523841.HFX_0260	5.664e-53	200.0	COG0421@1|root,COG0477@1|root,arCOG00050@2157|Archaea,arCOG02682@2157|Archaea,2XUEJ@28890|Euryarchaeota,23T1E@183963|Halobacteria	183963|Halobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
TH3_k127_7749726_80	671143.DAMO_0994	5.382e-29	124.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	MA20_16670	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TH3_k127_7749726_16	595460.RRSWK_04461	3.7e-147	479.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_7749726_13	944480.ATUV01000001_gene1378	2.606e-160	523.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M6BJ@213113|Desulfurellales	28221|Deltaproteobacteria	NU	Type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
TH3_k127_7749726_41	296591.Bpro_2193	6.196e-79	280.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VIFK@28216|Betaproteobacteria,4AB3M@80864|Comamonadaceae	28216|Betaproteobacteria	H	MoeA domain protein domain I and II	moeA1	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
TH3_k127_7749726_43	269084.syc1734_d	2.482e-71	252.0	COG1043@1|root,COG1043@2|Bacteria,1G3IU@1117|Cyanobacteria,1H2QC@1129|Synechococcus	1117|Cyanobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
TH3_k127_7749726_57	1121468.AUBR01000001_gene497	1.102e-52	194.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,42EWM@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
TH3_k127_7749726_90	1177154.Y5S_00007	8.499e-14	83.0	2FA92@1|root,342HR@2|Bacteria,1NYCG@1224|Proteobacteria,1SQ6S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7749726_28	497964.CfE428DRAFT_2172	4.593e-104	354.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,46SRG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Competence-damaged protein	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
TH3_k127_7749726_73	478741.JAFS01000001_gene1519	1.806e-36	139.0	COG1141@1|root,COG1141@2|Bacteria,46T2D@74201|Verrucomicrobia,37GX8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
TH3_k127_7749726_31	485916.Dtox_1215	1.473e-101	350.0	COG1007@1|root,COG1007@2|Bacteria,1TR55@1239|Firmicutes,25ED8@186801|Clostridia,25ZY3@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TH3_k127_7749726_22	1156937.MFUM_940006	5.226e-125	417.0	COG1008@1|root,COG1008@2|Bacteria,46SE4@74201|Verrucomicrobia,37GAQ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TH3_k127_7749726_8	1156937.MFUM_940007	1.283e-181	588.0	COG1009@1|root,COG1009@2|Bacteria,46SDU@74201|Verrucomicrobia,37GBS@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
TH3_k127_7749726_77	1156937.MFUM_940008	7.957e-32	128.0	COG0713@1|root,COG0713@2|Bacteria,46SX4@74201|Verrucomicrobia,37GV9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
TH3_k127_7749726_62	794903.OPIT5_18130	3.791e-49	179.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
TH3_k127_7749726_76	1156937.MFUM_940009	1.35e-32	132.0	COG0839@1|root,COG0839@2|Bacteria,46T5P@74201|Verrucomicrobia,37GUV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
TH3_k127_7749726_52	452637.Oter_0478	6.692e-60	212.0	COG1143@1|root,COG1143@2|Bacteria,46SNT@74201|Verrucomicrobia,3K7UR@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
TH3_k127_7749726_27	240016.ABIZ01000001_gene4776	3.603e-108	361.0	COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,2ITZ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
TH3_k127_7749726_11	497964.CfE428DRAFT_0528	3.132e-175	568.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,46S6S@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
TH3_k127_7749726_88	1395587.P364_0100010	3.122e-15	78.0	COG0675@1|root,COG0675@2|Bacteria	2|Bacteria	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178,HTH_OrfB_IS605
TH3_k127_7749726_5	497964.CfE428DRAFT_0527	2.505e-195	619.0	COG1894@1|root,COG1894@2|Bacteria,46S8J@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
TH3_k127_7749726_87	946077.W5A_01680	1.452e-15	87.0	2E35R@1|root,32Y5N@2|Bacteria,4P5KG@976|Bacteroidetes,1IAK3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7749726_64	497964.CfE428DRAFT_0527	1.399e-48	178.0	COG1894@1|root,COG1894@2|Bacteria,46S8J@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
TH3_k127_7749726_17	694431.DESACE_01260	4.204e-145	472.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2M6DK@213113|Desulfurellales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
TH3_k127_7749726_47	1396418.BATQ01000167_gene1768	3.193e-65	228.0	COG0852@1|root,COG0852@2|Bacteria,46STM@74201|Verrucomicrobia,2IU60@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
TH3_k127_7749726_39	1123070.KB899248_gene182	1.309e-81	274.0	COG0377@1|root,COG0377@2|Bacteria,46SMM@74201|Verrucomicrobia,2ITJ6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
TH3_k127_7749726_100	543728.Vapar_0410	0.0001101	52.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2VSMV@28216|Betaproteobacteria,4AEE0@80864|Comamonadaceae	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
TH3_k127_7749726_63	278957.ABEA03000094_gene4754	3.835e-49	184.0	COG0811@1|root,COG0811@2|Bacteria,46SUA@74201|Verrucomicrobia,3K7EH@414999|Opitutae	414999|Opitutae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
TH3_k127_7749726_55	278957.ABEA03000094_gene4751	4.514e-54	192.0	COG4508@1|root,COG4508@2|Bacteria,46VH7@74201|Verrucomicrobia,3K7ZP@414999|Opitutae	414999|Opitutae	S	dUTPase	-	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
TH3_k127_7749726_65	324602.Caur_2619	2.004e-48	177.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TH3_k127_7749726_7	497964.CfE428DRAFT_2513	3.791e-189	604.0	COG1543@1|root,COG1543@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K03406,ko:K16149	ko00500,ko01100,ko01110,ko02020,ko02030,map00500,map01100,map01110,map02020,map02030	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko02035	-	GH57	-	DUF1957,Glyco_hydro_57,Glyco_transf_4,Glycos_transf_1
TH3_k127_7749726_78	497964.CfE428DRAFT_4931	1.318e-31	139.0	COG3330@1|root,COG3330@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4912)	-	-	-	ko:K09942	-	-	-	-	ko00000	-	-	-	DUF4912,Rho_N
TH3_k127_7749726_91	335543.Sfum_2943	3.555e-13	75.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg,dCache_1
TH3_k127_7749726_71	1415778.JQMM01000001_gene261	1.561e-41	162.0	COG2982@1|root,COG2982@2|Bacteria,1N0N6@1224|Proteobacteria,1SF4A@1236|Gammaproteobacteria,1JA7J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA
TH3_k127_7749726_53	290512.Paes_2385	1.099e-58	216.0	COG1262@1|root,COG1262@2|Bacteria,1FF87@1090|Chlorobi	1090|Chlorobi	O	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TH3_k127_7749726_25	1123242.JH636434_gene3629	2.874e-118	391.0	COG2706@1|root,COG2706@2|Bacteria,2IY02@203682|Planctomycetes	203682|Planctomycetes	G	COG2706 3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
TH3_k127_7749726_50	1173026.Glo7428_3316	5.776e-61	218.0	COG0432@1|root,COG0432@2|Bacteria,1G61Z@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
TH3_k127_7749726_12	696747.NIES39_L01370	6.66e-167	532.0	COG1902@1|root,COG1902@2|Bacteria,1FZYT@1117|Cyanobacteria,1H861@1150|Oscillatoriales	1117|Cyanobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
TH3_k127_7749726_98	472759.Nhal_3601	1.503e-06	55.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,1RP9Y@1236|Gammaproteobacteria,1WWGU@135613|Chromatiales	135613|Chromatiales	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	PGPGW,TerC
TH3_k127_7749726_48	583355.Caka_2665	1.722e-63	229.0	COG1226@1|root,2Z7ZD@2|Bacteria	2|Bacteria	P	Ion transport protein	-	-	-	ko:K08714	-	-	-	-	ko00000,ko02000	1.A.1.14	-	-	Ion_trans
TH3_k127_7749726_14	452637.Oter_1438	5.841e-160	508.0	COG0861@1|root,COG0861@2|Bacteria,46TS9@74201|Verrucomicrobia,3K8X2@414999|Opitutae	414999|Opitutae	P	membrane	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
TH3_k127_7749726_54	386456.JQKN01000006_gene1261	6.002e-58	214.0	COG3177@1|root,arCOG03110@2157|Archaea,2XUN8@28890|Euryarchaeota,23PGE@183925|Methanobacteria	183925|Methanobacteria	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
TH3_k127_7749726_86	1379270.AUXF01000003_gene3363	5.802e-17	83.0	COG0347@1|root,COG0347@2|Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	DUF190,P-II
TH3_k127_7749726_29	1122221.JHVI01000015_gene1707	4.611e-104	349.0	COG3329@1|root,COG3329@2|Bacteria,1WJER@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
TH3_k127_7749726_45	1128421.JAGA01000001_gene2371	5.336e-66	229.0	COG0041@1|root,COG0041@2|Bacteria,2NPN4@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0008150,GO:0040007	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.purE,iNJ661.Rv3275c	AIRC
TH3_k127_7749726_21	1521187.JPIM01000035_gene3407	6.259e-126	417.0	COG0026@1|root,COG0026@2|Bacteria,2G5PV@200795|Chloroflexi,375PJ@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
TH3_k127_7749726_33	314230.DSM3645_18936	1.419e-100	349.0	COG0591@1|root,COG0591@2|Bacteria,2IY5N@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TH3_k127_7749726_97	314230.DSM3645_18931	8.488e-08	60.0	2EJH6@1|root,33D83@2|Bacteria,2J1HK@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3311)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3311
TH3_k127_7749726_72	1403819.BATR01000120_gene4247	1.587e-37	152.0	COG3932@1|root,COG3932@2|Bacteria,46T8A@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Exopolysaccharide synthesis, ExoD	-	-	-	-	-	-	-	-	-	-	-	-	ExoD
TH3_k127_7749726_79	240016.ABIZ01000001_gene760	1.071e-30	136.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like,Usp
TH3_k127_7749726_83	1089550.ATTH01000001_gene756	3.19e-22	108.0	COG0589@1|root,COG0589@2|Bacteria,4PICI@976|Bacteroidetes,1FK3M@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TH3_k127_7749726_84	452637.Oter_1439	5.536e-21	98.0	COG1544@1|root,COG1544@2|Bacteria,46WN8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
TH3_k127_7749726_38	1403819.BATR01000124_gene4434	8.066e-85	298.0	COG2738@1|root,COG2738@2|Bacteria,46TH9@74201|Verrucomicrobia,2IUJW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
TH3_k127_7749726_23	452637.Oter_1440	3.09e-121	395.0	COG0583@1|root,COG0583@2|Bacteria,46TZU@74201|Verrucomicrobia	74201|Verrucomicrobia	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
TH3_k127_7749726_66	452637.Oter_1109	7.101e-47	179.0	COG4276@1|root,COG4276@2|Bacteria,46X6Q@74201|Verrucomicrobia,3K9Y1@414999|Opitutae	414999|Opitutae	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7749726_67	595460.RRSWK_06787	4.093e-43	164.0	COG3449@1|root,COG3449@2|Bacteria,2J2ST@203682|Planctomycetes	203682|Planctomycetes	L	SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
TH3_k127_7749726_4	530564.Psta_0993	1.756e-268	837.0	COG1574@1|root,COG1574@2|Bacteria,2IX0K@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
TH3_k127_7749726_20	748247.AZKH_2522	5.709e-129	413.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2VJFI@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
TH3_k127_7749726_42	1403819.BATR01000182_gene6271	1.925e-74	256.0	COG0778@1|root,COG0778@2|Bacteria,46V9P@74201|Verrucomicrobia,2IU8H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Nitroreductase family	-	-	1.5.1.34	ko:K10679	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
TH3_k127_7749726_34	1403819.BATR01000053_gene1630	1.424e-100	332.0	COG1741@1|root,COG1741@2|Bacteria,46SRJ@74201|Verrucomicrobia,2IU6M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
TH3_k127_7749726_44	1396141.BATP01000025_gene912	1.84e-67	240.0	COG0583@1|root,COG0583@2|Bacteria,46ZKT@74201|Verrucomicrobia,2IVKZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TH3_k127_7749726_37	522306.CAP2UW1_1318	1.667e-87	299.0	COG3597@1|root,COG3597@2|Bacteria,1QG9J@1224|Proteobacteria,2VIRR@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	DUF533,TerB
TH3_k127_7749726_24	671143.DAMO_0966	1.003e-119	400.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2NPE1@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	spoIVFB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
TH3_k127_7749726_82	452637.Oter_1439	4.14e-26	113.0	COG1544@1|root,COG1544@2|Bacteria,46WN8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
TH3_k127_7749726_36	1403819.BATR01000124_gene4434	2.051e-88	300.0	COG2738@1|root,COG2738@2|Bacteria,46TH9@74201|Verrucomicrobia,2IUJW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
TH3_k127_7749726_46	1396141.BATP01000047_gene3930	1.004e-65	228.0	COG3476@1|root,COG3476@2|Bacteria,46SXT@74201|Verrucomicrobia,2IVZD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	TspO/MBR family	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
TH3_k127_7749726_70	472759.Nhal_2122	1.105e-41	160.0	COG0702@1|root,COG0702@2|Bacteria,1QV7M@1224|Proteobacteria,1T2N4@1236|Gammaproteobacteria,1WYK0@135613|Chromatiales	135613|Chromatiales	GM	intermediate-associated protein 30	-	-	-	-	-	-	-	-	-	-	-	-	CIA30
TH3_k127_7749726_35	926569.ANT_25430	1.239e-94	326.0	COG2335@1|root,COG2335@2|Bacteria,2G7AJ@200795|Chloroflexi	200795|Chloroflexi	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
TH3_k127_7749726_60	1125863.JAFN01000001_gene83	4.272e-50	186.0	COG2020@1|root,COG2020@2|Bacteria,1RBUU@1224|Proteobacteria,42UT0@68525|delta/epsilon subdivisions,2WQKM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
TH3_k127_7749726_96	452637.Oter_1440	3.565e-08	57.0	COG0583@1|root,COG0583@2|Bacteria,46TZU@74201|Verrucomicrobia	74201|Verrucomicrobia	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
TH3_k127_7749726_59	926566.Terro_3682	3.094e-51	190.0	COG2152@1|root,COG2152@2|Bacteria,3Y5H3@57723|Acidobacteria,2JM4K@204432|Acidobacteriia	204432|Acidobacteriia	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_7749726_6	497964.CfE428DRAFT_2154	3.517e-192	635.0	COG1674@1|root,COG1674@2|Bacteria,46SCV@74201|Verrucomicrobia	74201|Verrucomicrobia	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
TH3_k127_7749726_49	99598.Cal7507_3402	1.293e-62	223.0	2EY4W@1|root,33RDQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7749726_19	99598.Cal7507_3403	4.269e-131	433.0	COG0754@1|root,COG0754@2|Bacteria	2|Bacteria	E	glutathionylspermidine amidase activity	gsp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008884,GO:0008885,GO:0016787,GO:0016810,GO:0016811,GO:0016874,GO:0016879,GO:0016880,GO:0044424,GO:0044444,GO:0044464	3.5.1.78,6.3.1.8	ko:K01460	ko00480,ko01100,map00480,map01100	-	R01917,R01918	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_3484	CHAP,GSP_synth
TH3_k127_7749726_58	99598.Cal7507_3404	7.104e-52	193.0	2F1DQ@1|root,33UEG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7749726_69	1232410.KI421424_gene1610	4.592e-42	175.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,43SWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
TH3_k127_7749726_9	240016.ABIZ01000001_gene5947	1.701e-179	569.0	COG0686@1|root,COG0686@2|Bacteria,46S7U@74201|Verrucomicrobia,2ITXS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Alanine dehydrogenase/PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
TH3_k127_7749726_15	1122947.FR7_4282	1.637e-157	511.0	COG2271@1|root,COG2271@2|Bacteria,1TS33@1239|Firmicutes,4H38R@909932|Negativicutes	909932|Negativicutes	G	Major Facilitator	-	-	-	ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
TH3_k127_7749726_10	1210884.HG799463_gene9560	1.141e-176	568.0	COG0578@1|root,COG0578@2|Bacteria,2IX2V@203682|Planctomycetes	203682|Planctomycetes	C	Glycerol-3-phosphate dehydrogenase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
TH3_k127_7749726_30	679935.Alfi_2300	1.476e-103	344.0	COG0647@1|root,COG0647@2|Bacteria,4NG49@976|Bacteroidetes,2FRNM@200643|Bacteroidia	976|Bacteroidetes	G	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
TH3_k127_7749726_0	497964.CfE428DRAFT_0238	0.0	1270.0	COG2010@1|root,COG2010@2|Bacteria,46TSG@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
TH3_k127_7749726_18	886293.Sinac_7008	1.107e-138	445.0	COG4102@1|root,COG4102@2|Bacteria,2IX5T@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TH3_k127_7751879_1	443144.GM21_1665	6.785e-47	181.0	COG1215@1|root,COG1215@2|Bacteria,1MW1E@1224|Proteobacteria,42ZKN@68525|delta/epsilon subdivisions,2WUTQ@28221|Deltaproteobacteria,43VG8@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TH3_k127_7751879_0	497964.CfE428DRAFT_4864	5.295e-52	196.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7751879_2	886293.Sinac_6489	7.974e-20	94.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
TH3_k127_7783351_1	886293.Sinac_7008	1.858e-251	781.0	COG4102@1|root,COG4102@2|Bacteria,2IX5T@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TH3_k127_7783351_4	234267.Acid_7032	3.285e-105	356.0	COG2271@1|root,COG2271@2|Bacteria,3Y3FW@57723|Acidobacteria	57723|Acidobacteria	G	Organic Anion Transporter Polypeptide (OATP) family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TH3_k127_7783351_0	1403819.BATR01000135_gene4816	0.0	1025.0	COG4692@1|root,COG4692@2|Bacteria,46SE5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,VCBS
TH3_k127_7783351_5	1121430.JMLG01000019_gene1656	1.103e-84	297.0	COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,24CA4@186801|Clostridia,260IP@186807|Peptococcaceae	186801|Clostridia	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
TH3_k127_7783351_6	497964.CfE428DRAFT_0998	7.179e-52	192.0	COG0350@1|root,COG0350@2|Bacteria	2|Bacteria	L	methylated-DNA-[protein]-cysteine S-methyltransferase activity	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
TH3_k127_7783351_7	497964.CfE428DRAFT_1520	5.63e-43	160.0	COG0251@1|root,COG0251@2|Bacteria,46T40@74201|Verrucomicrobia	74201|Verrucomicrobia	J	endoribonuclease L-PSP	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Ribonuc_L-PSP
TH3_k127_7783351_3	1121875.KB907547_gene3471	6.071e-117	393.0	2C20F@1|root,32R9J@2|Bacteria,4P0SP@976|Bacteroidetes	976|Bacteroidetes	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
TH3_k127_7783351_2	278957.ABEA03000215_gene4275	4.354e-158	512.0	COG0165@1|root,COG0165@2|Bacteria,46UYU@74201|Verrucomicrobia,3K76F@414999|Opitutae	414999|Opitutae	E	Argininosuccinate lyase C-terminal	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
TH3_k127_7789871_1	1070319.CAGGBEG34_190038	3.658e-73	259.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,1JZWN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	D-alanyl-d-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
TH3_k127_7789871_3	768066.HELO_3427	6.777e-05	50.0	COG3339@1|root,COG3339@2|Bacteria,1N9BI@1224|Proteobacteria,1SC8Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
TH3_k127_7789871_0	1123508.JH636444_gene5364	2.715e-158	507.0	COG1082@1|root,COG1082@2|Bacteria,2IXRD@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
TH3_k127_7789871_2	1396141.BATP01000059_gene2565	1.189e-69	242.0	COG1012@1|root,COG1012@2|Bacteria,46TX0@74201|Verrucomicrobia,2IUT7@203494|Verrucomicrobiae	2|Bacteria	C	Aldehyde dehydrogenase family	mmsA	GO:0000166,GO:0003674,GO:0003824,GO:0004029,GO:0004030,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0006066,GO:0006067,GO:0006069,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0022900,GO:0031974,GO:0034308,GO:0036094,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0050896,GO:0051287,GO:0055114,GO:0070013,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901615	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_4667,iYL1228.KPN_04670	Aldedh
TH3_k127_7805507_22	1283287.KB822578_gene2242	3.994e-21	100.0	COG1215@1|root,COG1215@2|Bacteria,2GJTE@201174|Actinobacteria,4DNZE@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
TH3_k127_7805507_4	1123242.JH636436_gene130	7.869e-165	537.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
TH3_k127_7805507_10	1123508.JH636439_gene1318	2.683e-64	237.0	COG1459@1|root,COG1459@2|Bacteria,2IXYZ@203682|Planctomycetes	203682|Planctomycetes	U	Type 4 fimbrial assembly protein pilC	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
TH3_k127_7805507_16	1125863.JAFN01000001_gene2967	1.562e-36	143.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
TH3_k127_7805507_31	745411.B3C1_05932	0.0002703	51.0	COG4970@1|root,COG4970@2|Bacteria,1NBWI@1224|Proteobacteria,1S5MN@1236|Gammaproteobacteria,1J9VA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	general secretion pathway protein	xpsH	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
TH3_k127_7805507_30	1479238.JQMZ01000001_gene267	6.582e-05	50.0	COG2165@1|root,COG2165@2|Bacteria,1NH8A@1224|Proteobacteria,2UK2Q@28211|Alphaproteobacteria,43YW6@69657|Hyphomonadaceae	28211|Alphaproteobacteria	NU	General secretion pathway protein I	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
TH3_k127_7805507_28	1123508.JH636450_gene7091	6.833e-07	60.0	COG4795@1|root,COG4795@2|Bacteria,2J03I@203682|Planctomycetes	203682|Planctomycetes	U	General secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
TH3_k127_7805507_18	1123242.JH636435_gene2166	2.985e-32	143.0	COG3156@1|root,COG3156@2|Bacteria,2IXHV@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
TH3_k127_7805507_29	1540221.JQNI01000002_gene1751	8.43e-06	58.0	COG4972@1|root,COG4972@2|Bacteria,1WJKT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
TH3_k127_7805507_21	1121921.KB898712_gene2233	3.818e-23	115.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,2PN33@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	NU	Bacterial type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
TH3_k127_7805507_12	661478.OP10G_4206	2.64e-46	183.0	COG1450@1|root,COG1450@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	gspD	-	-	ko:K02453,ko:K03219	ko03070,ko05111,map03070,map05111	M00331,M00332,M00542	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15,3.A.6.1,3.A.6.3	-	-	Secretin,Secretin_N
TH3_k127_7805507_15	644282.Deba_1655	2.602e-40	168.0	COG3852@1|root,COG3852@2|Bacteria,1RCUD@1224|Proteobacteria,42R9I@68525|delta/epsilon subdivisions,2WN53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
TH3_k127_7805507_8	1304885.AUEY01000116_gene2847	1.762e-123	410.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M2X@68525|delta/epsilon subdivisions,2WJMY@28221|Deltaproteobacteria,2MIYR@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TH3_k127_7805507_5	349741.Amuc_2115	1.745e-138	452.0	COG0172@1|root,COG0172@2|Bacteria,46S70@74201|Verrucomicrobia,2ITV1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Seryl-tRNA synthetase N-terminal domain	-	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
TH3_k127_7805507_6	404589.Anae109_0139	5.142e-132	436.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2YU1G@29|Myxococcales	28221|Deltaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
TH3_k127_7805507_13	1156937.MFUM_300024	3.094e-46	184.0	COG0681@1|root,COG0681@2|Bacteria,46SR0@74201|Verrucomicrobia,37FWK@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
TH3_k127_7805507_1	1051632.TPY_0699	1.023e-223	707.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3WCEY@538999|Clostridiales incertae sedis	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
TH3_k127_7805507_2	497964.CfE428DRAFT_3344	1.001e-222	718.0	COG1204@1|root,COG1204@2|Bacteria,46SCW@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
TH3_k127_7805507_0	497964.CfE428DRAFT_3556	3.817e-286	895.0	COG1185@1|root,COG1185@2|Bacteria,46SBP@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
TH3_k127_7805507_20	273068.TTE1388	1.41e-26	110.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,42GTG@68295|Thermoanaerobacterales	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
TH3_k127_7805507_7	1396141.BATP01000003_gene4934	2.196e-126	458.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
TH3_k127_7805507_24	1303518.CCALI_00044	7.296e-15	85.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_7805507_32	1038869.AXAN01000074_gene4073	0.000622	54.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria,2WI8K@28216|Betaproteobacteria,1KIR6@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Domain of unknown function (DUF4982)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
TH3_k127_7805507_26	378806.STAUR_1759	4.673e-12	81.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria	1224|Proteobacteria	G	Domain of unknown function (DUF4982)	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
TH3_k127_7805507_3	926560.KE387023_gene1701	1.48e-195	637.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF3365,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TH3_k127_7805507_25	1219084.AP014508_gene1338	2.151e-13	82.0	COG0745@1|root,COG0745@2|Bacteria,2GDAM@200918|Thermotogae	200918|Thermotogae	T	PFAM response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
TH3_k127_7805507_17	497964.CfE428DRAFT_5353	1.026e-35	151.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
TH3_k127_7805507_11	224325.AF_2211	9.474e-51	187.0	COG0537@1|root,arCOG00419@2157|Archaea,2XWGT@28890|Euryarchaeota,2466N@183980|Archaeoglobi	183980|Archaeoglobi	F	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
TH3_k127_7805507_9	497964.CfE428DRAFT_6337	1.396e-117	386.0	COG1702@1|root,COG1702@2|Bacteria,46S7S@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
TH3_k127_7805507_27	945713.IALB_1565	2.536e-11	74.0	COG0319@1|root,COG0319@2|Bacteria	2|Bacteria	C	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.6.99.2,3.5.4.5	ko:K01489,ko:K03474,ko:K03595,ko:K07042	ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100	M00124	R01878,R02485,R05838,R08221	RC00074,RC00514,RC01476	ko00000,ko00001,ko00002,ko01000,ko03009,ko03029	-	-	-	UPF0054
TH3_k127_7805507_14	1449126.JQKL01000073_gene3044	1.052e-41	162.0	COG2928@1|root,COG2928@2|Bacteria,1V6FM@1239|Firmicutes,24JQ1@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
TH3_k127_7805507_19	497964.CfE428DRAFT_4583	5.377e-29	129.0	COG1381@1|root,COG1381@2|Bacteria,46VUW@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
TH3_k127_7805507_23	1173025.GEI7407_1434	4.197e-21	100.0	COG3832@1|root,COG3832@2|Bacteria,1G83T@1117|Cyanobacteria,1HDP1@1150|Oscillatoriales	1117|Cyanobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7824187_2	96561.Dole_1104	0.0001621	46.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,42NBB@68525|delta/epsilon subdivisions,2WIMD@28221|Deltaproteobacteria,2MIEB@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM ResB family protein	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
TH3_k127_7824187_0	665942.HMPREF1022_00427	1.032e-77	274.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,2M7UJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
TH3_k127_7824187_1	1232410.KI421421_gene3835	2.188e-70	251.0	COG0755@1|root,COG0755@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2WIKV@28221|Deltaproteobacteria,43W41@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
TH3_k127_7834714_8	452637.Oter_1368	3.539e-70	246.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TH3_k127_7834714_1	251221.35211765	1.156e-191	629.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TH3_k127_7834714_3	1183438.GKIL_4354	7.356e-171	564.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TH3_k127_7834714_6	452637.Oter_1900	5.193e-111	363.0	COG1136@1|root,COG1136@2|Bacteria,46TVQ@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_7834714_5	1183438.GKIL_2517	1.391e-129	429.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TH3_k127_7834714_12	686340.Metal_0410	2.378e-20	96.0	2E3EN@1|root,32YDN@2|Bacteria,1N7N7@1224|Proteobacteria,1SCSD@1236|Gammaproteobacteria,1XGTV@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
TH3_k127_7834714_11	205918.Psyr_0855	9.424e-21	105.0	28IQ1@1|root,2Z8PV@2|Bacteria,1NYS1@1224|Proteobacteria,1RPR2@1236|Gammaproteobacteria,1Z57B@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	-	-	IV02_13120	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7834714_7	177439.DP2558	8.955e-81	301.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	ko:K02057,ko:K07459,ko:K10110	ko02010,map02010	M00194,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.22,3.A.1.2	-	-	AAA_11,AAA_12,AAA_13,AAA_23
TH3_k127_7834714_9	177439.DP2557	8.509e-35	145.0	2EVII@1|root,33NYR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7834714_4	234267.Acid_4169	8.221e-163	524.0	COG5000@1|root,COG5000@2|Bacteria,3Y2TD@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
TH3_k127_7834714_0	234267.Acid_4168	6.923e-194	620.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TH3_k127_7834714_2	266265.Bxe_B2149	3.195e-191	612.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria,1JZMS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3,1.2.1.39,1.2.1.8	ko:K00128,ko:K00130,ko:K00146	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TH3_k127_7834714_10	1268240.ATFI01000013_gene1201	1.228e-22	104.0	COG3401@1|root,COG3401@2|Bacteria,4NFM5@976|Bacteroidetes,2FPSM@200643|Bacteroidia,4ANKU@815|Bacteroidaceae	976|Bacteroidetes	S	candidate rhamnogalacturonan lyase, polysaccharide lyase family 11 protein K01238	-	-	4.2.2.23	ko:K18197	-	-	-	-	ko00000,ko01000	-	PL11	-	-
TH3_k127_7867526_2	269797.Mbar_A1574	5.746e-56	209.0	COG1262@1|root,arCOG03517@2157|Archaea,2Y27Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TH3_k127_7867526_8	1303518.CCALI_01330	5.745e-10	71.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_7867526_1	269797.Mbar_A1995	1.689e-142	482.0	arCOG02516@1|root,arCOG02538@1|root,arCOG02516@2157|Archaea,arCOG02538@2157|Archaea,2Y7RK@28890|Euryarchaeota,2NBKX@224756|Methanomicrobia	2157|Archaea	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,He_PIG,PKD,PQQ_3,Peptidase_S8,S-layer
TH3_k127_7867526_3	1192034.CAP_3675	2.408e-42	162.0	2AQBM@1|root,31FHR@2|Bacteria,1QA8C@1224|Proteobacteria,434WG@68525|delta/epsilon subdivisions,2X920@28221|Deltaproteobacteria,2Z1HS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7867526_11	160488.PP_1915	0.0002695	49.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1YZ00@136845|Pseudomonas putida group	1236|Gammaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0050896,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TH3_k127_7867526_4	926550.CLDAP_37740	9.235e-33	135.0	COG1670@1|root,COG1670@2|Bacteria,2G6UG@200795|Chloroflexi	200795|Chloroflexi	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TH3_k127_7867526_0	1303518.CCALI_02122	2.124e-220	724.0	2C33Y@1|root,33VR5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7867526_5	1396141.BATP01000040_gene2082	3.871e-16	93.0	COG2247@1|root,COG3291@1|root,COG4733@1|root,COG5492@1|root,COG2247@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,46TXW@74201|Verrucomicrobia	74201|Verrucomicrobia	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	PA14
TH3_k127_7867526_9	1396141.BATP01000022_gene455	1.409e-08	68.0	COG4675@1|root,COG4675@2|Bacteria,46X85@74201|Verrucomicrobia,2IUYY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
TH3_k127_7867526_10	196490.AUEZ01000233_gene1409	1.34e-06	55.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2TUGE@28211|Alphaproteobacteria,3JX5I@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
TH3_k127_7867526_7	1415779.JOMH01000001_gene3115	1.378e-12	73.0	COG1848@1|root,COG1848@2|Bacteria,1PBM6@1224|Proteobacteria	1224|Proteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
TH3_k127_7867526_6	865937.Gilli_1969	9.404e-13	76.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	yeeJ	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	DUF5122,Peptidase_S74,YadA_head,YadA_stalk
TH3_k127_7926050_25	497964.CfE428DRAFT_2142	9.8e-07	55.0	COG3391@1|root,COG3391@2|Bacteria,46TN0@74201|Verrucomicrobia	74201|Verrucomicrobia	O	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
TH3_k127_7926050_3	439235.Dalk_4289	1.328e-227	726.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,42M9A@68525|delta/epsilon subdivisions,2WJ3Y@28221|Deltaproteobacteria,2MJBT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11,3.5.1.97	ko:K01434,ko:K07116	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
TH3_k127_7926050_13	452637.Oter_2422	1.174e-69	240.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
TH3_k127_7926050_17	1192034.CAP_4540	6.654e-46	191.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,438BB@68525|delta/epsilon subdivisions,2X3KN@28221|Deltaproteobacteria,2YWFV@29|Myxococcales	1224|Proteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08282,ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12
TH3_k127_7926050_27	1120966.AUBU01000002_gene1998	1.124e-05	55.0	2BXUX@1|root,32R23@2|Bacteria,4NR4Y@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7926050_5	530564.Psta_1668	1.842e-128	426.0	COG1520@1|root,COG1520@2|Bacteria,2IY7A@203682|Planctomycetes	203682|Planctomycetes	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
TH3_k127_7926050_14	575540.Isop_0616	2.65e-68	247.0	COG0526@1|root,COG0526@2|Bacteria,2J06Z@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
TH3_k127_7926050_2	452637.Oter_1374	2.038e-234	736.0	COG3534@1|root,COG3534@2|Bacteria,46TJZ@74201|Verrucomicrobia,3K9HJ@414999|Opitutae	414999|Opitutae	G	alpha-L-arabinofuranosidase domain protein	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
TH3_k127_7926050_6	1122917.KB899665_gene3972	5.417e-116	384.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,26W35@186822|Paenibacillaceae	91061|Bacilli	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TH3_k127_7926050_0	452637.Oter_3359	3.774e-315	988.0	COG1643@1|root,COG1643@2|Bacteria,46TMT@74201|Verrucomicrobia,3K7J2@414999|Opitutae	414999|Opitutae	L	ATP-dependent helicase C-terminal	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
TH3_k127_7926050_23	517417.Cpar_0783	5.154e-10	62.0	2DIK4@1|root,303HI@2|Bacteria,1FFNU@1090|Chlorobi	1090|Chlorobi	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
TH3_k127_7926050_24	118173.KB235914_gene1673	9.625e-10	63.0	COG5548@1|root,COG5548@2|Bacteria,1G997@1117|Cyanobacteria,1HCVD@1150|Oscillatoriales	1117|Cyanobacteria	S	Transmembrane proteins 14C	-	-	-	-	-	-	-	-	-	-	-	-	Tmemb_14
TH3_k127_7926050_21	1117315.AHCA01000002_gene3124	4.417e-17	88.0	2EVE0@1|root,33NUD@2|Bacteria,1NMKR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
TH3_k127_7926050_20	28072.Nos7524_4621	4.781e-22	113.0	COG0823@1|root,COG2304@1|root,COG3209@1|root,COG3210@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1GQ0G@1117|Cyanobacteria,1HN8U@1161|Nostocales	1117|Cyanobacteria	MU	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,He_PIG,RHS_repeat
TH3_k127_7926050_19	700598.Niako_5012	7.142e-35	156.0	COG2385@1|root,COG2385@2|Bacteria	2|Bacteria	D	sporulation resulting in formation of a cellular spore	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Amidase_2,Amidase_3,ChW,SpoIID
TH3_k127_7926050_22	203119.Cthe_2878	1.145e-12	79.0	COG3271@1|root,COG3271@2|Bacteria,1VXMN@1239|Firmicutes,251IP@186801|Clostridia,3WPTR@541000|Ruminococcaceae	186801|Clostridia	S	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39
TH3_k127_7926050_1	497964.CfE428DRAFT_5133	5.46e-285	885.0	COG1164@1|root,COG1164@2|Bacteria,46UYB@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
TH3_k127_7926050_12	156889.Mmc1_0977	1.376e-78	273.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2TQMD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	3-beta hydroxysteroid dehydrogenase	MA20_24380	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind
TH3_k127_7926050_10	1304885.AUEY01000001_gene3217	6.793e-105	357.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIB8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TH3_k127_7926050_18	1329516.JPST01000035_gene3088	4.6e-39	158.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli,27BT7@186824|Thermoactinomycetaceae	91061|Bacilli	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
TH3_k127_7926050_16	497964.CfE428DRAFT_4165	2.982e-56	200.0	COG0245@1|root,COG0245@2|Bacteria,46T29@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
TH3_k127_7926050_15	1396141.BATP01000003_gene5267	2.723e-66	229.0	COG0394@1|root,COG0394@2|Bacteria,46T52@74201|Verrucomicrobia,2IUEU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
TH3_k127_7926050_8	452637.Oter_2356	1.964e-112	373.0	COG0016@1|root,COG0016@2|Bacteria,46S6R@74201|Verrucomicrobia,3K7U5@414999|Opitutae	414999|Opitutae	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
TH3_k127_7926050_11	452637.Oter_3509	3.827e-104	353.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_7926050_7	886293.Sinac_7126	5.786e-115	384.0	COG1524@1|root,COG1524@2|Bacteria,2IYCV@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
TH3_k127_7926050_4	452637.Oter_0961	2.485e-153	495.0	COG1171@1|root,COG1171@2|Bacteria,46TW9@74201|Verrucomicrobia,3K73X@414999|Opitutae	414999|Opitutae	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
TH3_k127_7926050_9	1125863.JAFN01000001_gene1869	6.099e-109	362.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
TH3_k127_7947802_1	1267535.KB906767_gene1411	2.453e-154	503.0	COG1506@1|root,COG1506@2|Bacteria,3Y357@57723|Acidobacteria,2JIKY@204432|Acidobacteriia	204432|Acidobacteriia	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
TH3_k127_7947802_0	379066.GAU_3508	1.251e-192	615.0	COG4584@1|root,COG4584@2|Bacteria,1ZV8R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
TH3_k127_7947802_2	379066.GAU_3509	6.191e-105	346.0	COG1484@1|root,COG1484@2|Bacteria,1ZV5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
TH3_k127_7947802_4	338966.Ppro_1841	5.504e-06	54.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	2.7.7.49	ko:K00986,ko:K07497	-	-	-	-	ko00000,ko01000	-	-	-	HTH_32,rve,rve_3
TH3_k127_7947802_3	234267.Acid_3621	4.316e-19	90.0	COG1629@1|root,COG4771@2|Bacteria,3Y7FP@57723|Acidobacteria	57723|Acidobacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_7951803_10	313628.LNTAR_08241	7.932e-75	258.0	COG0141@1|root,COG0141@2|Bacteria	2|Bacteria	E	histidinol dehydrogenase activity	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_2362,iG2583_1286.G2583_2541,iUTI89_1310.UTI89_C2293,ic_1306.c2547	Histidinol_dh
TH3_k127_7951803_1	1267535.KB906767_gene933	6.533e-201	636.0	COG3669@1|root,COG3669@2|Bacteria,3Y37T@57723|Acidobacteria,2JKVF@204432|Acidobacteriia	204432|Acidobacteriia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
TH3_k127_7951803_14	391625.PPSIR1_04398	4.207e-30	125.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,42RJS@68525|delta/epsilon subdivisions,2WQSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
TH3_k127_7951803_2	497964.CfE428DRAFT_5146	2.764e-179	575.0	COG1541@1|root,COG1541@2|Bacteria,46UTU@74201|Verrucomicrobia	74201|Verrucomicrobia	H	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
TH3_k127_7951803_4	497964.CfE428DRAFT_5147	3.956e-121	409.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TH3_k127_7951803_6	1396418.BATQ01000133_gene4024	2.744e-108	359.0	COG1801@1|root,COG1801@2|Bacteria,46TUG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
TH3_k127_7951803_3	211165.AJLN01000098_gene5214	1.648e-127	423.0	COG0477@1|root,COG0477@2|Bacteria,1G1NG@1117|Cyanobacteria,1JKCQ@1189|Stigonemataceae	1117|Cyanobacteria	EGP	Transmembrane secretion effector	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_3
TH3_k127_7951803_17	871585.BDGL_001653	3.698e-05	55.0	COG1714@1|root,COG1714@2|Bacteria,1NB1Z@1224|Proteobacteria,1S5BT@1236|Gammaproteobacteria,3NK23@468|Moraxellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
TH3_k127_7951803_11	497964.CfE428DRAFT_0566	2.672e-62	218.0	COG0590@1|root,COG0590@2|Bacteria,46SZZ@74201|Verrucomicrobia	74201|Verrucomicrobia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
TH3_k127_7951803_15	290397.Adeh_3736	1.758e-10	66.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
TH3_k127_7951803_9	234267.Acid_7362	7.727e-94	317.0	COG1210@1|root,COG1210@2|Bacteria,3Y39W@57723|Acidobacteria	2|Bacteria	M	PFAM Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0646	NTP_transferase
TH3_k127_7951803_7	240016.ABIZ01000001_gene4452	5.772e-105	350.0	COG1577@1|root,COG1577@2|Bacteria,46V85@74201|Verrucomicrobia	74201|Verrucomicrobia	I	mevalonate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GHMP_kinases_C,GHMP_kinases_N
TH3_k127_7951803_5	1396418.BATQ01000025_gene5262	3.776e-109	367.0	COG0520@1|root,COG0520@2|Bacteria,46SC0@74201|Verrucomicrobia,2IW1B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
TH3_k127_7951803_0	385682.AFSL01000102_gene55	1.379e-205	649.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia,3XJ70@558415|Marinilabiliaceae	976|Bacteroidetes	P	FeoA	-	-	-	-	-	-	-	-	-	-	-	-	FeoA,FeoB_C,FeoB_N,Gate
TH3_k127_7951803_8	945713.IALB_0510	2.897e-104	349.0	COG0370@1|root,COG0370@2|Bacteria	2|Bacteria	P	ferrous iron transmembrane transporter activity	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
TH3_k127_7951803_12	945713.IALB_0509	2.716e-62	227.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03322,ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	2.A.55.2.6,2.A.55.3	-	-	Fe_dep_repr_C,FeoA
TH3_k127_7951803_13	497964.CfE428DRAFT_2157	2.142e-30	122.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	DUF971
TH3_k127_8007692_6	313628.LNTAR_20062	3.832e-10	70.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_8007692_2	382464.ABSI01000013_gene1723	4.253e-109	383.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Redoxin,Thioredoxin_8,UnbV_ASPIC,VCBS
TH3_k127_8007692_0	1396141.BATP01000030_gene3719	4.367e-238	798.0	COG3119@1|root,COG3211@1|root,COG3656@1|root,COG5337@1|root,COG3119@2|Bacteria,COG3211@2|Bacteria,COG3656@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	phoX	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	CotH,DUF839
TH3_k127_8007692_5	1396141.BATP01000034_gene4198	5.55e-34	154.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
TH3_k127_8007692_1	509191.AEDB02000022_gene2935	5.663e-112	385.0	COG2006@1|root,COG2006@2|Bacteria,1VRZ8@1239|Firmicutes,24Z9V@186801|Clostridia,3WN5G@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Dockerin_1
TH3_k127_8007692_3	240016.ABIZ01000001_gene5229	2.826e-107	359.0	COG0673@1|root,COG0673@2|Bacteria,46UEY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_8007692_4	314345.SPV1_01182	1.882e-42	166.0	28N94@1|root,2ZBD8@2|Bacteria,1MWA4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8007692_7	706587.Desti_0542	0.0001764	46.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria,2MQ7A@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
TH3_k127_8016427_0	240016.ABIZ01000001_gene4289	1.538e-141	459.0	COG0553@1|root,COG0553@2|Bacteria,46U66@74201|Verrucomicrobia,2ITU2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,SNF2_N
TH3_k127_8016427_5	497964.CfE428DRAFT_4000	2.409e-10	63.0	2A7P8@1|root,30WMJ@2|Bacteria,46TBD@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Hypothetical protein (DUF2513)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2513
TH3_k127_8016427_6	1173020.Cha6605_5997	7.859e-10	70.0	COG1357@1|root,COG2026@1|root,COG1357@2|Bacteria,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	ko:K06218,ko:K06408	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
TH3_k127_8016427_7	1462527.CCDM010000002_gene685	2.525e-06	49.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8016427_2	530564.Psta_2300	2.082e-70	255.0	COG0673@1|root,COG0673@2|Bacteria,2IX0C@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_8016427_1	1122604.JONR01000033_gene34	6.066e-75	259.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X4GZ@135614|Xanthomonadales	135614|Xanthomonadales	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TH3_k127_8016427_3	452637.Oter_2330	2.181e-67	244.0	COG2972@1|root,COG2972@2|Bacteria,46XGC@74201|Verrucomicrobia,3K8E3@414999|Opitutae	414999|Opitutae	T	Signal transduction histidine kinase, LytS	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
TH3_k127_8016427_4	1123242.JH636434_gene5136	1.501e-30	123.0	COG1960@1|root,COG1960@2|Bacteria,2IXMD@203682|Planctomycetes	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TH3_k127_8043227_2	497964.CfE428DRAFT_3329	3.267e-133	430.0	COG0498@1|root,COG0498@2|Bacteria	2|Bacteria	E	threonine synthase activity	thrC1	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TH3_k127_8043227_6	316067.Geob_0976	7.021e-31	129.0	28RF4@1|root,2ZDU9@2|Bacteria,1P7NC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8043227_7	638303.Thal_1379	1.276e-30	122.0	COG1977@1|root,COG1977@2|Bacteria,2G563@200783|Aquificae	200783|Aquificae	H	TIGRFAM MoaD family protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
TH3_k127_8043227_9	497964.CfE428DRAFT_3331	1.255e-26	112.0	COG1135@1|root,COG1135@2|Bacteria,46WAD@74201|Verrucomicrobia	74201|Verrucomicrobia	P	NIL domain	-	-	-	-	-	-	-	-	-	-	-	-	NIL
TH3_k127_8043227_10	478741.JAFS01000002_gene623	1.781e-22	101.0	COG0355@1|root,COG0355@2|Bacteria,46T0F@74201|Verrucomicrobia,37GUN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
TH3_k127_8043227_1	497964.CfE428DRAFT_4489	8.619e-230	720.0	COG0055@1|root,COG0055@2|Bacteria,46SCC@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
TH3_k127_8043227_4	497964.CfE428DRAFT_4490	7.007e-92	310.0	COG0224@1|root,COG0224@2|Bacteria,46SGU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
TH3_k127_8043227_0	497964.CfE428DRAFT_4491	1.55e-251	783.0	COG0056@1|root,COG0056@2|Bacteria,46SB5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
TH3_k127_8043227_8	1403819.BATR01000049_gene1414	3.351e-27	116.0	COG0712@1|root,COG0712@2|Bacteria,46TC4@74201|Verrucomicrobia,2IUUI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	ATP synthase delta (OSCP) subunit	-	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
TH3_k127_8043227_5	497964.CfE428DRAFT_4493	1.721e-43	164.0	COG0711@1|root,COG0711@2|Bacteria,46SYI@74201|Verrucomicrobia	74201|Verrucomicrobia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
TH3_k127_8043227_11	497964.CfE428DRAFT_4494	5.125e-18	93.0	2DS8G@1|root,33EZT@2|Bacteria,46T9M@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ATP synthase subunit C	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
TH3_k127_8043227_3	497964.CfE428DRAFT_4495	2.864e-110	365.0	COG0356@1|root,COG0356@2|Bacteria,46SVZ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
TH3_k127_8053109_2	32057.KB217478_gene7545	1.479e-48	185.0	COG2730@1|root,COG2730@2|Bacteria,1G3EZ@1117|Cyanobacteria	1117|Cyanobacteria	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
TH3_k127_8053109_0	861299.J421_5653	1.104e-127	424.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_8053109_1	1267535.KB906767_gene3448	1.474e-73	262.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_6,F5_F8_type_C,Pectate_lyase_3
TH3_k127_8053109_3	1122611.KB903963_gene4742	6.56e-37	152.0	COG2362@1|root,COG2362@2|Bacteria,2GK6A@201174|Actinobacteria,4EGCR@85012|Streptosporangiales	201174|Actinobacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
TH3_k127_8053109_4	316274.Haur_1999	0.0005826	50.0	COG0515@1|root,COG2931@1|root,COG3266@1|root,COG3386@1|root,COG0515@2|Bacteria,COG2931@2|Bacteria,COG3266@2|Bacteria,COG3386@2|Bacteria,2G9CG@200795|Chloroflexi,374U7@32061|Chloroflexia	32061|Chloroflexia	G	LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,Laminin_G_3
TH3_k127_805362_0	1121382.JQKG01000022_gene1479	1.24e-77	272.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	mtsE	-	-	ko:K11089	ko05322,map05322	-	-	-	ko00000,ko00001	-	-	-	TROVE,VWA_2
TH3_k127_805362_1	756272.Plabr_0774	3.57e-17	82.0	COG3012@1|root,COG3012@2|Bacteria,2J1HA@203682|Planctomycetes	203682|Planctomycetes	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
TH3_k127_805362_2	515635.Dtur_1664	6.815e-17	95.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
TH3_k127_8063883_12	452637.Oter_1279	2.266e-12	74.0	COG1579@1|root,COG1579@2|Bacteria	2|Bacteria	-	-	oppA	-	2.1.1.80,3.1.1.61	ko:K13582,ko:K13924,ko:K15580	ko01501,ko02010,ko02020,ko02024,ko02030,ko04112,map01501,map02010,map02020,map02024,map02030,map04112	M00439,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	CheB_methylest,CheR,CheR_N,DUF285,Flg_new,HWE_HK,PAS_10,SBP_bac_5
TH3_k127_8063883_0	452637.Oter_2454	7.036e-251	785.0	COG0659@1|root,COG0659@2|Bacteria,46THR@74201|Verrucomicrobia,3K7K8@414999|Opitutae	414999|Opitutae	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
TH3_k127_8063883_5	530564.Psta_0956	9.932e-70	247.0	COG0584@1|root,COG0584@2|Bacteria,2IZ1A@203682|Planctomycetes	203682|Planctomycetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
TH3_k127_8063883_15	1123242.JH636434_gene4823	1.766e-07	56.0	COG2133@1|root,COG2133@2|Bacteria,2IWVG@203682|Planctomycetes	203682|Planctomycetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8063883_1	1307759.JOMJ01000004_gene2934	4.555e-135	443.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,42Q03@68525|delta/epsilon subdivisions,2WMFQ@28221|Deltaproteobacteria,2MBAU@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Transposase domain (DUF772)	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
TH3_k127_8063883_17	1448139.AI20_18275	4.2e-05	52.0	COG2207@1|root,COG2207@2|Bacteria,1QTTB@1224|Proteobacteria,1T1GI@1236|Gammaproteobacteria,1Y5WC@135624|Aeromonadales	135624|Aeromonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
TH3_k127_8063883_8	883080.HMPREF9697_03953	4e-25	111.0	COG1487@1|root,COG1487@2|Bacteria,1RIB5@1224|Proteobacteria,2VGZ3@28211|Alphaproteobacteria,3JZA4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
TH3_k127_8063883_13	562970.Btus_3182	8.382e-11	65.0	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
TH3_k127_8063883_21	1469607.KK073768_gene4628	0.0004793	45.0	2EHRH@1|root,33BH9@2|Bacteria,1GA8J@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4926)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4926
TH3_k127_8063883_20	1492922.GY26_17225	0.0003676	45.0	COG2944@1|root,COG2944@2|Bacteria,1NH2C@1224|Proteobacteria,1TBCJ@1236|Gammaproteobacteria,1JBN2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MqsA_antitoxin
TH3_k127_8063883_4	1396141.BATP01000006_gene5432	6.034e-114	394.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
TH3_k127_8063883_7	167539.Pro_1266	3.215e-34	140.0	2DMQB@1|root,32SZR@2|Bacteria	2|Bacteria	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
TH3_k127_8063883_6	167539.Pro_1264	1.998e-39	156.0	COG1285@1|root,COG1285@2|Bacteria	2|Bacteria	E	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
TH3_k127_8063883_18	1101192.KB910516_gene2785	9.106e-05	46.0	COG0265@1|root,COG0265@2|Bacteria,1MV63@1224|Proteobacteria,2TS54@28211|Alphaproteobacteria,1JRCY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Trypsin_2
TH3_k127_8063883_16	1229487.AMYW01000032_gene3041	4.269e-06	61.0	COG1361@1|root,COG3210@1|root,COG3291@1|root,COG4932@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia,2P0KQ@237|Flavobacterium	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
TH3_k127_8063883_14	1122609.AUGT01000002_gene3860	1.322e-08	69.0	COG3227@1|root,COG4412@1|root,COG3227@2|Bacteria,COG4412@2|Bacteria,2GJEW@201174|Actinobacteria,4DPZQ@85009|Propionibacteriales	201174|Actinobacteria	E	Fungalysin/Thermolysin Propeptide Motif	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,Peptidase_M4,Peptidase_M4_C
TH3_k127_8063883_9	1396141.BATP01000028_gene2285	2.17e-24	121.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
TH3_k127_8063883_10	27923.ML204429a-PA	1.43e-17	99.0	2CMMP@1|root,2QQVA@2759|Eukaryota,38DQG@33154|Opisthokonta,3BC84@33208|Metazoa	33208|Metazoa	S	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
TH3_k127_8063883_11	177437.HRM2_06590	2.11e-14	79.0	COG0399@1|root,COG0399@2|Bacteria,1PRVB@1224|Proteobacteria,431RA@68525|delta/epsilon subdivisions,2X518@28221|Deltaproteobacteria,2MP3U@213118|Desulfobacterales	28221|Deltaproteobacteria	M	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
TH3_k127_8063883_19	767817.Desgi_1747	0.0001278	45.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1,Y2_Tnp,Zn_Tnp_IS91
TH3_k127_8063883_2	999419.HMPREF1077_00773	9.282e-125	413.0	COG0673@1|root,COG0673@2|Bacteria,4NGGS@976|Bacteroidetes,2FTQH@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_8063883_3	555779.Dthio_PD2105	4.368e-117	384.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,43B03@68525|delta/epsilon subdivisions,2X6E6@28221|Deltaproteobacteria,2MH1Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
TH3_k127_8089573_1	1268240.ATFI01000008_gene2201	4.909e-84	297.0	COG2006@1|root,COG2006@2|Bacteria,4P0ZM@976|Bacteroidetes,2FR0W@200643|Bacteroidia,4APQE@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
TH3_k127_8089573_3	331678.Cphamn1_0748	3.839e-21	93.0	COG0286@1|root,COG0286@2|Bacteria,1FERX@1090|Chlorobi	1090|Chlorobi	H	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
TH3_k127_8089573_2	365046.Rta_00040	6.006e-67	230.0	COG0286@1|root,COG0286@2|Bacteria,1NN38@1224|Proteobacteria,2VNIU@28216|Betaproteobacteria,4AGSN@80864|Comamonadaceae	28216|Betaproteobacteria	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
TH3_k127_8089573_0	518766.Rmar_1740	1.289e-106	362.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1FK20@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_8097557_7	1340493.JNIF01000003_gene4296	3.839e-91	319.0	2DZRA@1|root,32VGT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
TH3_k127_8097557_9	886293.Sinac_0384	2.491e-53	201.0	COG3055@1|root,COG3055@2|Bacteria,2IY7R@203682|Planctomycetes	203682|Planctomycetes	E	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
TH3_k127_8097557_13	1090320.KB900605_gene3525	0.0009778	51.0	COG3250@1|root,COG3250@2|Bacteria,1NYBH@1224|Proteobacteria,2U1SW@28211|Alphaproteobacteria,2K1C6@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolases family 2	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2
TH3_k127_8097557_8	679199.HMPREF9332_01395	1.316e-74	283.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,2FMUE@200643|Bacteroidia	976|Bacteroidetes	G	F5 8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
TH3_k127_8097557_4	497964.CfE428DRAFT_3514	3.002e-116	386.0	COG3055@1|root,COG3055@2|Bacteria,46T14@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8097557_1	1396141.BATP01000009_gene2639	3.63e-208	657.0	COG0477@1|root,COG2814@2|Bacteria,46Z9E@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TH3_k127_8097557_6	886293.Sinac_2107	5.799e-113	373.0	COG0329@1|root,COG0329@2|Bacteria,2IYE2@203682|Planctomycetes	203682|Planctomycetes	EM	Dihydrodipicolinate synthase N-acetylneuraminate lyase	-	-	4.1.3.3	ko:K01639	ko00520,map00520	-	R01811	RC00159,RC00600	ko00000,ko00001,ko01000	-	-	-	DHDPS
TH3_k127_8097557_2	344747.PM8797T_29708	2.794e-179	568.0	COG4409@1|root,COG4409@2|Bacteria,2IYPT@203682|Planctomycetes	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Big_2,DUF4091,FIVAR,Laminin_G_3
TH3_k127_8097557_3	1396418.BATQ01000150_gene2240	1.121e-173	554.0	COG2942@1|root,COG2942@2|Bacteria,46UIM@74201|Verrucomicrobia,2ITK6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	5.1.3.8	ko:K01787	ko00520,map00520	-	R01207	RC00290	ko00000,ko00001,ko01000	-	-	-	GlcNAc_2-epim
TH3_k127_8097557_10	1303518.CCALI_02288	1.114e-48	188.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
TH3_k127_8097557_0	344747.PM8797T_10954	2.14e-215	677.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_8097557_11	1303518.CCALI_02638	5.071e-11	73.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_8097557_5	1396141.BATP01000007_gene5570	1.032e-115	407.0	COG5306@1|root,COG5306@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TH3_k127_8104202_0	1210884.HG799470_gene14529	3.691e-313	983.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,2IY0D@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
TH3_k127_8104202_4	521674.Plim_1627	5.254e-12	76.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_8104202_5	1396141.BATP01000006_gene5432	9.891e-05	54.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
TH3_k127_8104202_3	452637.Oter_3823	3.645e-67	241.0	COG3693@1|root,COG3934@1|root,COG3693@2|Bacteria,COG3934@2|Bacteria,46S7C@74201|Verrucomicrobia,3K7ED@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8104202_1	452637.Oter_3823	8.207e-178	576.0	COG3693@1|root,COG3934@1|root,COG3693@2|Bacteria,COG3934@2|Bacteria,46S7C@74201|Verrucomicrobia,3K7ED@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8104202_2	1403819.BATR01000031_gene981	9.864e-107	361.0	COG1793@1|root,COG1793@2|Bacteria,46TK9@74201|Verrucomicrobia,2IV60@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TH3_k127_8123738_8	1298867.AUES01000042_gene3563	1.549e-79	303.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria	1224|Proteobacteria	MU	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
TH3_k127_8123738_17	883078.HMPREF9695_00489	2.063e-06	58.0	COG2801@1|root,COG2801@2|Bacteria,1MWVQ@1224|Proteobacteria,2TQPC@28211|Alphaproteobacteria,3JZ69@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29,HTH_32,rve
TH3_k127_8123738_0	94624.Bpet1409	7.444e-240	767.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2VK01@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Resolvase domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TH3_k127_8123738_12	94624.Bpet1408	2.886e-37	147.0	COG3415@1|root,COG3415@2|Bacteria,1RKUV@1224|Proteobacteria,2WFVI@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29
TH3_k127_8123738_16	420324.KI911932_gene324	4.062e-16	82.0	2EHAG@1|root,3394C@2|Bacteria,1NK4E@1224|Proteobacteria,2UJZB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Family of unknown function (DUF5372)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5372
TH3_k127_8123738_19	1205908.AKXW01000001_gene3223	2.835e-05	52.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,1MWVQ@1224|Proteobacteria,1RN12@1236|Gammaproteobacteria,1XVDW@135623|Vibrionales	135623|Vibrionales	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
TH3_k127_8123738_15	340177.Cag_0614	1.085e-17	102.0	COG1357@1|root,COG2931@1|root,COG3210@1|root,COG4625@1|root,COG1357@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	rhgB	-	4.2.2.23	ko:K07004,ko:K18195	-	-	-	-	ko00000,ko01000	-	PL4	-	CBM-like,RhgB_N,fn3_3
TH3_k127_8123738_4	864702.OsccyDRAFT_2745	1.096e-108	404.0	COG2931@1|root,COG2931@2|Bacteria,1GHDS@1117|Cyanobacteria	1117|Cyanobacteria	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
TH3_k127_8123738_18	929703.KE386491_gene2364	2.839e-06	64.0	COG2373@1|root,COG3209@1|root,COG3291@1|root,COG4386@1|root,COG4932@1|root,COG2373@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4386@2|Bacteria,COG4932@2|Bacteria,4NJRF@976|Bacteroidetes,47PMY@768503|Cytophagia	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TH3_k127_8123738_11	929556.Solca_2367	3.421e-42	183.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,HYR,HemolysinCabind,IgGFc_binding
TH3_k127_8123738_9	1173263.Syn7502_00897	2.646e-79	306.0	COG2931@1|root,COG3210@1|root,COG3386@1|root,COG5276@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3386@2|Bacteria,COG5276@2|Bacteria,1G1I0@1117|Cyanobacteria,1H1YG@1129|Synechococcus	1117|Cyanobacteria	Q	Q COG2931 RTX toxins and related Ca2 -binding proteins	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FG-GAP,HemolysinCabind,P_proprotein,Peptidase_S8
TH3_k127_8123738_13	1122933.JNIY01000008_gene1840	1.604e-33	152.0	COG1361@1|root,COG2373@1|root,COG3391@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG3391@2|Bacteria,2I8F1@201174|Actinobacteria,4F2TR@85016|Cellulomonadaceae	201174|Actinobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,He_PIG,fn3
TH3_k127_8123738_7	96561.Dole_1791	1.789e-83	316.0	COG1044@1|root,COG1361@1|root,COG1653@1|root,COG1044@2|Bacteria,COG1361@2|Bacteria,COG1653@2|Bacteria,1N4S6@1224|Proteobacteria,43BRE@68525|delta/epsilon subdivisions,2X729@28221|Deltaproteobacteria,2MNRP@213118|Desulfobacterales	1224|Proteobacteria	G	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8123738_6	378806.STAUR_2903	1.135e-85	323.0	COG3291@1|root,COG4257@1|root,COG3291@2|Bacteria,COG4257@2|Bacteria,1R7A1@1224|Proteobacteria,42Y4U@68525|delta/epsilon subdivisions,2WU72@28221|Deltaproteobacteria,2YZXW@29|Myxococcales	28221|Deltaproteobacteria	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,IgGFc_binding
TH3_k127_8123738_10	340177.Cag_0615	5.928e-63	241.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
TH3_k127_8123738_14	118005.AWNK01000004_gene1113	3.985e-19	96.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TH3_k127_8123738_3	340177.Cag_1408	3.213e-127	430.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02004,ko:K07798	ko02020,map02020	M00258	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.1.4,3.A.1,8.A.1	-	-	FtsX,HlyD_3,HlyD_D23,MacB_PCD
TH3_k127_8123738_1	340177.Cag_1407	5.915e-209	672.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K01993,ko:K13408,ko:K16922	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko01002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TH3_k127_8123738_2	1121447.JONL01000009_gene2551	1.145e-157	521.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2M8H9@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	-	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind
TH3_k127_8123738_5	1166018.FAES_pFAES01098	6.206e-98	334.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,47KSB@768503|Cytophagia	976|Bacteroidetes	Q	PFAM multicopper oxidase type 3	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
TH3_k127_8162663_7	1123242.JH636435_gene944	7.148e-11	68.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_8162663_0	452637.Oter_1389	1.107e-157	539.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TH3_k127_8162663_5	1123508.JH636439_gene990	2.819e-51	187.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
TH3_k127_8162663_1	1226994.AMZB01000119_gene3308	1.344e-116	395.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,1RR7T@1236|Gammaproteobacteria,1YD63@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TH3_k127_8162663_3	1089550.ATTH01000001_gene2299	9.049e-73	253.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120	-	R11339	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
TH3_k127_8162663_8	368407.Memar_0224	2.186e-07	59.0	COG2768@1|root,arCOG02448@2157|Archaea,2XW30@28890|Euryarchaeota,2N9AE@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4
TH3_k127_8162663_2	1125863.JAFN01000001_gene1137	1.715e-74	259.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,42TJM@68525|delta/epsilon subdivisions,2WQGN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	PFAM Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
TH3_k127_8162663_6	497964.CfE428DRAFT_1105	6.564e-43	173.0	COG1427@1|root,COG1427@2|Bacteria,46VTU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
TH3_k127_8162663_4	478741.JAFS01000001_gene1574	4.317e-55	203.0	COG1597@1|root,COG1597@2|Bacteria,46SR5@74201|Verrucomicrobia,37G0D@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
TH3_k127_8162663_9	497964.CfE428DRAFT_3787	2.469e-06	60.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8200364_2	1242864.D187_007612	2.168e-83	284.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,42M56@68525|delta/epsilon subdivisions,2WJ8W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM isocitrate isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
TH3_k127_8200364_1	1173028.ANKO01000194_gene6028	4.027e-125	446.0	COG3250@1|root,COG3250@2|Bacteria,1G4FY@1117|Cyanobacteria,1HA7W@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TH3_k127_8200364_0	1156937.MFUM_270006	7.544e-165	531.0	COG1154@1|root,COG1154@2|Bacteria,46SAU@74201|Verrucomicrobia,37G36@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
TH3_k127_8262056_0	1340493.JNIF01000004_gene640	3.661e-123	412.0	COG0399@1|root,COG0399@2|Bacteria,3Y2QT@57723|Acidobacteria	57723|Acidobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
TH3_k127_8262056_3	562983.HMPREF0433_01643	1.419e-05	54.0	COG4767@1|root,COG4767@2|Bacteria,1V7FP@1239|Firmicutes,4HNU9@91061|Bacilli,3WEZD@539002|Bacillales incertae sedis	91061|Bacilli	V	VanZ like family	vanZ	-	-	-	-	-	-	-	-	-	-	-	VanZ
TH3_k127_8262056_2	204536.SULAZ_0356	2.521e-29	121.0	COG2148@1|root,COG2148@2|Bacteria,2G3XH@200783|Aquificae	200783|Aquificae	M	sugar transferase	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
TH3_k127_826724_15	1267535.KB906767_gene3685	4.378e-08	56.0	COG5373@1|root,COG5373@2|Bacteria,3Y44X@57723|Acidobacteria,2JHIB@204432|Acidobacteriia	204432|Acidobacteriia	NU	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
TH3_k127_826724_12	717606.PaecuDRAFT_1429	6.187e-23	100.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,26ZAP@186822|Paenibacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
TH3_k127_826724_14	278957.ABEA03000086_gene2490	1.464e-12	77.0	COG2165@1|root,COG2165@2|Bacteria,46Y25@74201|Verrucomicrobia,3K8TK@414999|Opitutae	414999|Opitutae	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_826724_17	886293.Sinac_0208	2.342e-06	58.0	COG2165@1|root,COG2165@2|Bacteria,2IX5U@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_826724_8	1254432.SCE1572_38245	1.579e-56	226.0	COG1948@1|root,COG5276@1|root,COG4880@2|Bacteria,COG5276@2|Bacteria,1P2CI@1224|Proteobacteria	1224|Proteobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
TH3_k127_826724_4	1380391.JIAS01000012_gene4362	2.735e-109	374.0	COG3525@1|root,COG3525@2|Bacteria,1QR2G@1224|Proteobacteria,2UDYI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	beta-N-acetylglucosaminidase	-	GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564	-	-	-	-	-	-	-	-	-	-	NAGidase
TH3_k127_826724_9	649638.Trad_0164	2.007e-52	192.0	COG0454@1|root,COG0456@2|Bacteria,1WJ43@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TH3_k127_826724_5	714943.Mucpa_7156	2.633e-99	342.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
TH3_k127_826724_16	1123508.JH636442_gene4113	1.774e-07	62.0	COG1413@1|root,COG1413@2|Bacteria,2J418@203682|Planctomycetes	203682|Planctomycetes	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
TH3_k127_826724_18	1089553.Tph_c21120	4.657e-05	55.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,42GBG@68295|Thermoanaerobacterales	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
TH3_k127_826724_13	1042163.BRLA_c034220	1.843e-18	91.0	COG3743@1|root,COG3743@2|Bacteria	2|Bacteria	S	rRNA binding	-	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	DUF4332,HHH_5,Jacalin,Ribosomal_L4
TH3_k127_826724_3	761193.Runsl_2769	5.916e-112	375.0	COG0399@1|root,COG0399@2|Bacteria,4NE4B@976|Bacteroidetes,47M1Z@768503|Cytophagia	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TH3_k127_826724_6	530564.Psta_3476	3.918e-99	347.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,NPCBM
TH3_k127_826724_0	1123508.JH636445_gene6725	2.765e-231	737.0	COG1621@1|root,COG1621@2|Bacteria,2IXNN@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 32	-	-	3.2.1.65,3.2.1.80	ko:K01212,ko:K03332	ko00051,ko00500,map00051,map00500	-	R00879,R05624,R11311	RC03278	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
TH3_k127_826724_1	886293.Sinac_2434	1.372e-156	511.0	COG2730@1|root,COG3250@1|root,COG2730@2|Bacteria,COG3250@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
TH3_k127_826724_10	1396418.BATQ01000049_gene432	2.486e-39	171.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TH3_k127_826724_11	1123508.JH636447_gene7922	1.58e-24	123.0	COG0265@1|root,COG0265@2|Bacteria,2IX93@203682|Planctomycetes	203682|Planctomycetes	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_826724_2	1210884.HG799464_gene10641	7.951e-155	546.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXPU@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
TH3_k127_826724_7	530564.Psta_4257	1.516e-67	265.0	COG2755@1|root,COG5306@1|root,COG2755@2|Bacteria,COG5306@2|Bacteria,2IYTG@203682|Planctomycetes	203682|Planctomycetes	E	Domain of unknown function (DUF2341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2341,Laminin_G_3,SASA
TH3_k127_826962_8	526218.Sterm_1103	2.386e-72	255.0	COG1940@1|root,COG1940@2|Bacteria,378B8@32066|Fusobacteria	2|Bacteria	GK	Psort location Cytoplasmic, score 9.97	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TH3_k127_826962_13	1459636.NTE_00049	8.812e-28	119.0	COG2062@1|root,arCOG01992@2157|Archaea	2157|Archaea	T	TIGRFAM phosphohistidine phosphatase SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
TH3_k127_826962_15	857087.Metme_0945	1.096e-16	90.0	COG5607@1|root,COG5607@2|Bacteria	2|Bacteria	F	PFAM CHAD domain containing protein	sixA-2	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,His_Phos_1
TH3_k127_826962_0	497964.CfE428DRAFT_4539	6.602e-295	921.0	COG0855@1|root,COG0855@2|Bacteria,46SB4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
TH3_k127_826962_11	649831.L083_1093	1.18e-43	171.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4D8I2@85008|Micromonosporales	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
TH3_k127_826962_2	886293.Sinac_2390	3.669e-231	728.0	COG3119@1|root,COG3119@2|Bacteria,2IYRK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TH3_k127_826962_16	696747.NIES39_O06680	3.713e-10	72.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
TH3_k127_826962_7	575540.Isop_2533	3.723e-96	321.0	COG3485@1|root,COG3485@2|Bacteria,2IYK6@203682|Planctomycetes	203682|Planctomycetes	Q	PFAM intradiol ring-cleavage dioxygenase	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
TH3_k127_826962_5	521674.Plim_3842	5.193e-102	340.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
TH3_k127_826962_1	497964.CfE428DRAFT_5375	3.487e-247	786.0	COG0457@1|root,COG1225@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria,46U46@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TH3_k127_826962_17	768670.Calni_0018	0.0005322	49.0	COG0296@1|root,COG0296@2|Bacteria,2GFUK@200930|Deferribacteres	200930|Deferribacteres	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
TH3_k127_826962_10	329726.AM1_4632	7.937e-57	209.0	COG3735@1|root,COG3735@2|Bacteria,1G6DE@1117|Cyanobacteria	1117|Cyanobacteria	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
TH3_k127_826962_6	1396418.BATQ01000056_gene181	1.736e-99	335.0	COG4188@1|root,COG4188@2|Bacteria,46TTD@74201|Verrucomicrobia,2IVPV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
TH3_k127_826962_4	1123242.JH636435_gene1598	8.258e-105	349.0	COG2120@1|root,COG2120@2|Bacteria,2IY80@203682|Planctomycetes	203682|Planctomycetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TH3_k127_826962_9	314230.DSM3645_05180	1.366e-65	248.0	COG2159@1|root,COG2159@2|Bacteria,2IYMW@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
TH3_k127_826962_12	1267535.KB906767_gene1160	4.392e-29	135.0	COG2006@1|root,COG2006@2|Bacteria,3Y7N1@57723|Acidobacteria,2JNKP@204432|Acidobacteriia	204432|Acidobacteriia	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TH3_k127_826962_14	589873.EP13_06855	7.587e-23	106.0	COG3904@1|root,COG3904@2|Bacteria,1RK0H@1224|Proteobacteria,1SI4M@1236|Gammaproteobacteria,46BGA@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	periplasmic protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_826962_3	768671.ThimaDRAFT_4426	4.819e-164	532.0	COG1321@1|root,COG1321@2|Bacteria,1N8WG@1224|Proteobacteria,1SQA0@1236|Gammaproteobacteria,1X16W@135613|Chromatiales	1224|Proteobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_836404_52	1210884.HG799464_gene10380	1.179e-07	53.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
TH3_k127_836404_7	105559.Nwat_1144	1.146e-156	507.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1WWGK@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
TH3_k127_836404_19	300852.55771566	3.862e-104	353.0	COG0508@1|root,COG0508@2|Bacteria,1WI1G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TH3_k127_836404_25	497964.CfE428DRAFT_6358	5.386e-54	198.0	COG0204@1|root,COG0204@2|Bacteria,46VUC@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TH3_k127_836404_29	452637.Oter_3514	4.609e-44	170.0	2F286@1|root,33V6C@2|Bacteria,46V8R@74201|Verrucomicrobia,3K9H5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_836404_28	452637.Oter_3514	1.186e-44	171.0	2F286@1|root,33V6C@2|Bacteria,46V8R@74201|Verrucomicrobia,3K9H5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_836404_21	240016.ABIZ01000001_gene2631	3.213e-85	302.0	COG4745@1|root,COG4745@2|Bacteria,46T45@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TH3_k127_836404_23	5786.XP_003293123.1	6.983e-66	244.0	COG1409@1|root,KOG1378@2759|Eukaryota,3XGP6@554915|Amoebozoa	554915|Amoebozoa	S	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Pur_ac_phosph_N
TH3_k127_836404_47	497964.CfE428DRAFT_2341	3.871e-13	77.0	COG0238@1|root,COG0238@2|Bacteria,46TBC@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Ribosomal protein S18	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
TH3_k127_836404_36	1353529.M899_0700	1.099e-19	89.0	COG0267@1|root,COG0267@2|Bacteria,1Q1V0@1224|Proteobacteria,437HE@68525|delta/epsilon subdivisions,2MTDQ@213481|Bdellovibrionales,2X2QY@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
TH3_k127_836404_32	497964.CfE428DRAFT_2343	3.845e-31	130.0	COG1734@1|root,COG1734@2|Bacteria,46SVY@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
TH3_k127_836404_18	497964.CfE428DRAFT_3386	3.513e-104	345.0	COG1469@1|root,COG1469@2|Bacteria,46SIB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
TH3_k127_836404_30	497964.CfE428DRAFT_2588	4.707e-40	162.0	COG2374@1|root,COG2374@2|Bacteria,46VEK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TH3_k127_836404_5	452637.Oter_0138	1.432e-213	690.0	COG3934@1|root,COG3934@2|Bacteria,46YQT@74201|Verrucomicrobia,3KA0N@414999|Opitutae	414999|Opitutae	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_836404_37	65093.PCC7418_1380	5.425e-18	85.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
TH3_k127_836404_38	41431.PCC8801_4303	5.527e-18	87.0	2B7MA@1|root,320SE@2|Bacteria,1GH4S@1117|Cyanobacteria,3KIW8@43988|Cyanothece	1117|Cyanobacteria	S	Domain of unknown function (DUF4926)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4926
TH3_k127_836404_33	179408.Osc7112_2750	6.138e-23	105.0	2CBW6@1|root,332FE@2|Bacteria,1G8ER@1117|Cyanobacteria,1HD3G@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_836404_0	321327.CYA_2098	0.0	1191.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,1GYMF@1129|Synechococcus	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
TH3_k127_836404_17	398512.JQKC01000010_gene143	1.96e-108	368.0	COG1305@1|root,COG1305@2|Bacteria,1TT33@1239|Firmicutes,24B27@186801|Clostridia,3WPMU@541000|Ruminococcaceae	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
TH3_k127_836404_10	794903.OPIT5_05545	1.753e-133	443.0	COG0306@1|root,COG0306@2|Bacteria,46SDP@74201|Verrucomicrobia,3K7HD@414999|Opitutae	414999|Opitutae	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
TH3_k127_836404_9	1300345.LF41_544	9.921e-147	473.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1X3YD@135614|Xanthomonadales	135614|Xanthomonadales	P	phosphate transporter	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
TH3_k127_836404_24	1123073.KB899243_gene738	3.292e-60	217.0	COG1392@1|root,COG1392@2|Bacteria,1PKQF@1224|Proteobacteria,1SMFE@1236|Gammaproteobacteria,1X412@135614|Xanthomonadales	135614|Xanthomonadales	P	Pit accessory protein	VL23_21310	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
TH3_k127_836404_16	1123242.JH636435_gene3064	8.859e-109	368.0	COG0477@1|root,COG0477@2|Bacteria,2IX7U@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
TH3_k127_836404_14	497964.CfE428DRAFT_0621	9.789e-121	400.0	COG0150@1|root,COG0150@2|Bacteria,46SJ4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	AIR synthase related protein domain protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
TH3_k127_836404_51	1267535.KB906767_gene1409	8.375e-09	62.0	COG0491@1|root,COG0491@2|Bacteria,3Y44S@57723|Acidobacteria,2JHNA@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
TH3_k127_836404_2	497964.CfE428DRAFT_5970	3.817e-257	805.0	COG1217@1|root,COG1217@2|Bacteria,46SHA@74201|Verrucomicrobia	74201|Verrucomicrobia	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
TH3_k127_836404_35	1499967.BAYZ01000119_gene3208	6.838e-20	102.0	COG0859@1|root,COG0859@2|Bacteria,2NP5P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase, family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
TH3_k127_836404_27	1396418.BATQ01000166_gene1881	1.081e-46	173.0	COG0299@1|root,COG0615@1|root,COG0299@2|Bacteria,COG0615@2|Bacteria,46SUW@74201|Verrucomicrobia,2IWN8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	FIM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,Formyl_trans_N
TH3_k127_836404_26	646529.Desaci_3169	4.749e-49	188.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,2495M@186801|Clostridia,260GE@186807|Peptococcaceae	186801|Clostridia	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
TH3_k127_836404_43	926569.ANT_12920	1.566e-16	87.0	COG0455@1|root,COG0745@1|root,COG0455@2|Bacteria,COG0745@2|Bacteria,2G8KV@200795|Chloroflexi	200795|Chloroflexi	KT	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Response_reg
TH3_k127_836404_45	247490.KSU1_C1333	2.734e-14	83.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_836404_49	1123508.JH636444_gene5158	4.132e-11	75.0	COG2165@1|root,COG2165@2|Bacteria,2IZG4@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_836404_48	243090.RB7746	3.363e-11	68.0	COG3119@1|root,COG3119@2|Bacteria,2J2HN@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase activity	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
TH3_k127_836404_8	1267535.KB906767_gene952	2.214e-155	505.0	COG0673@1|root,COG0673@2|Bacteria,3Y65Y@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_836404_39	589865.DaAHT2_0883	6.02e-18	90.0	COG0824@1|root,COG0824@2|Bacteria,1PEBE@1224|Proteobacteria,42TIA@68525|delta/epsilon subdivisions,2WQ9X@28221|Deltaproteobacteria,2MMDF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
TH3_k127_836404_42	515635.Dtur_1559	2.792e-17	87.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	MA20_45160	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
TH3_k127_836404_1	309799.DICTH_1451	1.362e-263	834.0	COG0466@1|root,COG0466@2|Bacteria	2|Bacteria	O	ATP-dependent peptidase activity	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
TH3_k127_836404_53	187272.Mlg_0152	1.564e-06	59.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1WY05@135613|Chromatiales	135613|Chromatiales	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
TH3_k127_836404_54	497964.CfE428DRAFT_6108	0.0005239	52.0	2FCZ3@1|root,3451R@2|Bacteria,46WBW@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
TH3_k127_836404_3	1403819.BATR01000057_gene1772	4.148e-251	809.0	COG3474@1|root,COG3474@2|Bacteria,46TEP@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TH3_k127_836404_11	521674.Plim_0111	6.966e-133	438.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_836404_15	314230.DSM3645_04115	1.95e-113	382.0	COG1073@1|root,COG1073@2|Bacteria,2IYBP@203682|Planctomycetes	203682|Planctomycetes	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,Peptidase_S9
TH3_k127_836404_4	278957.ABEA03000010_gene3912	1.197e-234	741.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,3K7KM@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
TH3_k127_836404_46	1298863.AUEP01000009_gene40	3.523e-14	88.0	COG0681@1|root,COG0681@2|Bacteria,2HES2@201174|Actinobacteria,4DUMF@85009|Propionibacteriales	201174|Actinobacteria	U	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Peptidase_S24
TH3_k127_836404_50	682795.AciX8_3725	2.344e-10	75.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
TH3_k127_836404_44	756272.Plabr_1895	3.909e-16	88.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_836404_6	330214.NIDE0551	8.087e-166	550.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_16,TPR_7,TPR_8
TH3_k127_836404_13	118168.MC7420_3120	2.337e-127	431.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1G17N@1117|Cyanobacteria,1H72F@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
TH3_k127_836404_31	1121033.AUCF01000020_gene699	9.132e-39	154.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	yqfZ	-	-	-	-	-	-	-	-	-	-	-	LysM
TH3_k127_836404_22	452637.Oter_3080	1.445e-68	244.0	2CIBN@1|root,2Z8JT@2|Bacteria	2|Bacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
TH3_k127_836404_41	1254432.SCE1572_38305	2.165e-17	91.0	COG0631@1|root,COG0664@1|root,COG0631@2|Bacteria,COG0664@2|Bacteria,1R7UF@1224|Proteobacteria,42WUQ@68525|delta/epsilon subdivisions,2XA41@28221|Deltaproteobacteria,2YTYP@29|Myxococcales	28221|Deltaproteobacteria	T	SMART protein phosphatase 2C domain protein	pp2c12	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2,cNMP_binding
TH3_k127_836404_12	395493.BegalDRAFT_2362	8.535e-128	430.0	COG2831@1|root,COG2831@2|Bacteria,1MWEC@1224|Proteobacteria,1RYVX@1236|Gammaproteobacteria,461AE@72273|Thiotrichales	72273|Thiotrichales	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
TH3_k127_836404_20	395493.BegalDRAFT_0706	7.709e-89	321.0	COG3210@1|root,COG3210@2|Bacteria,1QMZZ@1224|Proteobacteria,1SG2Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	TIGRFAM filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act
TH3_k127_836404_34	1279009.ADICEAN_00140	2.705e-21	109.0	COG3291@1|root,COG3391@1|root,COG4935@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,4NDZC@976|Bacteroidetes,47SFQ@768503|Cytophagia	976|Bacteroidetes	O	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gly_rich,HYR,Laminin_G_3,PKD,SprB
TH3_k127_836404_40	1174528.JH992898_gene2139	9.336e-18	88.0	COG0793@1|root,COG0793@2|Bacteria,1G30Q@1117|Cyanobacteria,1JJ6B@1189|Stigonemataceae	1117|Cyanobacteria	M	Tricorn protease C1 domain	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41,Tricorn_C1
TH3_k127_8474585_9	1396141.BATP01000030_gene3715	1.472e-08	59.0	COG2010@1|root,COG2312@1|root,COG5337@1|root,COG5563@1|root,COG2010@2|Bacteria,COG2312@2|Bacteria,COG5337@2|Bacteria,COG5563@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
TH3_k127_8474585_1	382464.ABSI01000011_gene2469	1.025e-181	577.0	COG0827@1|root,COG0827@2|Bacteria	2|Bacteria	L	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8474585_0	382464.ABSI01000011_gene2470	8.542e-205	646.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
TH3_k127_8474585_2	382464.ABSI01000011_gene2471	3.472e-162	516.0	COG0451@1|root,COG0451@2|Bacteria,46V8P@74201|Verrucomicrobia	74201|Verrucomicrobia	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TH3_k127_8474585_3	118163.Ple7327_1377	4.752e-129	416.0	COG1208@1|root,COG1208@2|Bacteria,1G00Y@1117|Cyanobacteria,3VIEN@52604|Pleurocapsales	1117|Cyanobacteria	JM	COGs COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
TH3_k127_8474585_8	373994.Riv7116_4057	3.999e-21	108.0	COG5652@1|root,COG5652@2|Bacteria,1GC2R@1117|Cyanobacteria,1HM2P@1161|Nostocales	1117|Cyanobacteria	S	PFAM VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
TH3_k127_8474585_4	118163.Ple7327_1372	1.583e-90	316.0	COG0438@1|root,COG0438@2|Bacteria,1G3JN@1117|Cyanobacteria,3VM6P@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TH3_k127_8474585_5	247490.KSU1_C1701	3.134e-56	206.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TH3_k127_8474585_7	1449976.KALB_4422	5.272e-30	135.0	COG0500@1|root,COG0500@2|Bacteria,2INXQ@201174|Actinobacteria,4EDFK@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
TH3_k127_8474585_6	118163.Ple7327_1369	1.925e-52	192.0	COG2242@1|root,COG2242@2|Bacteria,1G543@1117|Cyanobacteria,3VKQU@52604|Pleurocapsales	1117|Cyanobacteria	H	Vibrio cholerae RfbT protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
TH3_k127_8495302_4	321327.CYA_0280	5.273e-23	111.0	COG5306@1|root,COG5306@2|Bacteria	2|Bacteria	-	-	exbB2	-	-	ko:K03561,ko:K12287	-	-	-	-	ko00000,ko02000,ko02044	1.A.30.2.1	-	-	DUF2341,Laminin_G_3,MotA_ExbB
TH3_k127_8495302_0	640081.Dsui_0821	0.0	1114.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,2KUMN@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA topoisomerase III	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
TH3_k127_8495302_1	243233.MCA2161	7.282e-167	549.0	COG3206@1|root,COG3206@2|Bacteria,1QX0J@1224|Proteobacteria,1RZ5A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8495302_5	1131269.AQVV01000100_gene2556	2.734e-17	91.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_8495302_3	236097.ADG881_1056	7.198e-57	210.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1XIGP@135619|Oceanospirillales	135619|Oceanospirillales	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
TH3_k127_8495302_2	1123242.JH636434_gene3333	9.469e-110	367.0	COG4692@1|root,COG4692@2|Bacteria,2J06F@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TH3_k127_8544384_3	497964.CfE428DRAFT_3455	2.848e-05	49.0	COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	2.3.1.241	ko:K02517,ko:K02843	ko00540,ko01100,map00540,map01100	M00060,M00080	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Lip_A_acyltrans
TH3_k127_8544384_0	497964.CfE428DRAFT_3455	2.646e-71	256.0	COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	2.3.1.241	ko:K02517,ko:K02843	ko00540,ko01100,map00540,map01100	M00060,M00080	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Lip_A_acyltrans
TH3_k127_8544384_1	1211813.CAPH01000017_gene773	2.41e-45	190.0	COG3408@1|root,COG3408@2|Bacteria,4P4HZ@976|Bacteroidetes	976|Bacteroidetes	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8544384_2	1123276.KB893246_gene561	1.892e-14	89.0	COG2010@1|root,COG3345@1|root,COG4625@1|root,COG2010@2|Bacteria,COG3345@2|Bacteria,COG4625@2|Bacteria,4NJDV@976|Bacteroidetes,47NUN@768503|Cytophagia	976|Bacteroidetes	E	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,NPCBM,PA14,RicinB_lectin_2
TH3_k127_8544384_4	869213.JCM21142_83218	3.701e-05	54.0	COG1621@1|root,COG1621@2|Bacteria,4NG4M@976|Bacteroidetes,47TNW@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
TH3_k127_8545446_0	497964.CfE428DRAFT_0257	6.57e-215	696.0	COG2844@1|root,COG2844@2|Bacteria,46SI6@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
TH3_k127_8545446_7	497964.CfE428DRAFT_0262	1.285e-41	161.0	COG0688@1|root,COG0688@2|Bacteria,46VRI@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
TH3_k127_8545446_6	497964.CfE428DRAFT_0263	8.021e-72	255.0	COG1183@1|root,COG1183@2|Bacteria,46SK0@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
TH3_k127_8545446_11	1201288.M900_1405	9.831e-16	88.0	COG1280@1|root,COG1280@2|Bacteria,1N227@1224|Proteobacteria,43DA6@68525|delta/epsilon subdivisions,2WVZZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
TH3_k127_8545446_9	204669.Acid345_3346	7.011e-33	136.0	2E0G4@1|root,32W27@2|Bacteria	2|Bacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
TH3_k127_8545446_5	497964.CfE428DRAFT_4519	5.413e-77	266.0	COG0388@1|root,COG0388@2|Bacteria,46T1B@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
TH3_k127_8545446_4	452637.Oter_2161	1.769e-167	531.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
TH3_k127_8545446_3	452637.Oter_2162	3.458e-172	544.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
TH3_k127_8545446_1	1403819.BATR01000114_gene3945	6.208e-207	653.0	COG3119@1|root,COG3119@2|Bacteria,46UET@74201|Verrucomicrobia,2IU4V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	C-terminal region of aryl-sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
TH3_k127_8545446_10	641524.ADICYQ_3837	3.616e-22	113.0	28MHM@1|root,2ZAUH@2|Bacteria,4NKMG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8545446_8	158500.BV97_03464	1.256e-35	138.0	COG1479@1|root,COG1479@2|Bacteria,1N34S@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
TH3_k127_8545446_12	349124.Hhal_1144	1.36e-12	70.0	COG2963@1|root,COG2963@2|Bacteria,1N8W3@1224|Proteobacteria,1SDIN@1236|Gammaproteobacteria,1WZRC@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase IS3 IS911	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
TH3_k127_8588817_1	1173027.Mic7113_4161	1.752e-181	588.0	COG2199@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1GQ1T@1117|Cyanobacteria,1HHSH@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,Response_reg
TH3_k127_8588817_2	1173027.Mic7113_4161	2.814e-166	586.0	COG2199@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1GQ1T@1117|Cyanobacteria,1HHSH@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,Response_reg
TH3_k127_8588817_12	395961.Cyan7425_0748	5.016e-52	186.0	COG0745@1|root,COG0745@2|Bacteria,1G6W5@1117|Cyanobacteria	1117|Cyanobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TH3_k127_8588817_4	794903.OPIT5_07185	1.488e-129	435.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,46V2T@74201|Verrucomicrobia,3K9RQ@414999|Opitutae	414999|Opitutae	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
TH3_k127_8588817_13	1380394.JADL01000003_gene4839	4.909e-23	104.0	COG2172@1|root,COG2172@2|Bacteria,1N9RD@1224|Proteobacteria,2UCGB@28211|Alphaproteobacteria,2JTM5@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
TH3_k127_8588817_16	1304874.JAFY01000001_gene2557	1.631e-10	65.0	COG1366@1|root,COG1366@2|Bacteria,3TC3U@508458|Synergistetes	508458|Synergistetes	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
TH3_k127_8588817_11	382464.ABSI01000011_gene3037	1.384e-77	262.0	COG3837@1|root,COG3837@2|Bacteria,46T0V@74201|Verrucomicrobia,2IU8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TH3_k127_8588817_8	215803.DB30_0528	1.287e-101	343.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8588817_9	1123242.JH636435_gene1120	8.245e-97	327.0	COG1506@1|root,COG1506@2|Bacteria,2J1ST@203682|Planctomycetes	203682|Planctomycetes	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
TH3_k127_8588817_14	1303518.CCALI_02658	1.777e-12	77.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_8588817_3	234267.Acid_2416	4.197e-165	532.0	COG4287@1|root,COG4287@2|Bacteria	2|Bacteria	S	PhoPQ-activated pathogenicity-related protein	pqaA	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
TH3_k127_8588817_5	1396418.BATQ01000058_gene90	7.847e-124	401.0	COG0684@1|root,COG0684@2|Bacteria,46SB3@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
TH3_k127_8588817_15	1303518.CCALI_02658	1.44e-10	71.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_8588817_7	1123242.JH636434_gene5137	4.146e-111	385.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
TH3_k127_8588817_0	1123242.JH636434_gene5138	5.277e-182	592.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,ETF,Fer4_10,Fer4_8,Fer4_9,Nitrate_red_gam
TH3_k127_8588817_6	1123242.JH636434_gene5139	4.58e-121	398.0	COG2025@1|root,COG2025@2|Bacteria,2J3Y1@203682|Planctomycetes	203682|Planctomycetes	C	Electron transfer flavoprotein domain	-	-	-	-	-	-	-	-	-	-	-	-	ETF,ETF_alpha
TH3_k127_8588817_10	1123242.JH636434_gene5140	1.14e-94	315.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
TH3_k127_8602029_20	452637.Oter_0747	4.866e-12	66.0	COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,3K82N@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
TH3_k127_8602029_12	452637.Oter_0748	2.725e-53	193.0	COG1143@1|root,COG1143@2|Bacteria,46YB4@74201|Verrucomicrobia,3K98S@414999|Opitutae	414999|Opitutae	C	4Fe-4S binding domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
TH3_k127_8602029_16	452637.Oter_0749	6.71e-43	163.0	COG0839@1|root,COG0839@2|Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
TH3_k127_8602029_17	452637.Oter_0750	1.802e-36	141.0	COG0713@1|root,COG0713@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
TH3_k127_8602029_2	452637.Oter_0751	9.609e-237	741.0	COG0651@1|root,COG0651@2|Bacteria	2|Bacteria	CP	ATP synthesis coupled electron transport	nuoL2	-	1.6.5.3	ko:K00341,ko:K05568	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
TH3_k127_8602029_18	1121413.JMKT01000008_gene1370	2.525e-25	114.0	2BR4E@1|root,32K2C@2|Bacteria,1Q2KP@1224|Proteobacteria,42X9C@68525|delta/epsilon subdivisions,2WSUZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8602029_1	452637.Oter_0753	1.92e-282	879.0	COG0651@1|root,COG0651@2|Bacteria,46U4G@74201|Verrucomicrobia,3K7M3@414999|Opitutae	2|Bacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	ndhD5	-	1.6.5.3	ko:K05568,ko:K05575	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2	-	iJN678.ndhD	Proton_antipo_M
TH3_k127_8602029_4	452637.Oter_0754	1.614e-215	681.0	COG1008@1|root,COG1008@2|Bacteria,46SE4@74201|Verrucomicrobia,3K7XF@414999|Opitutae	414999|Opitutae	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TH3_k127_8602029_6	452637.Oter_0755	1.926e-178	571.0	COG1007@1|root,COG1007@2|Bacteria,46W5N@74201|Verrucomicrobia,3K8V4@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TH3_k127_8602029_11	1267534.KB906754_gene3777	2.955e-88	295.0	COG1143@1|root,COG1143@2|Bacteria,3Y6N6@57723|Acidobacteria,2JKQS@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4_7
TH3_k127_8602029_8	1267534.KB906754_gene3776	4.101e-164	524.0	COG1005@1|root,COG1005@2|Bacteria,3Y6TS@57723|Acidobacteria,2JKJQ@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH dehydrogenase	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
TH3_k127_8602029_14	1267534.KB906754_gene3775	4.71e-46	172.0	COG0839@1|root,COG0839@2|Bacteria,3Y84Z@57723|Acidobacteria,2JN7E@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
TH3_k127_8602029_15	1267534.KB906754_gene3774	4.084e-43	160.0	COG0713@1|root,COG0713@2|Bacteria,3Y835@57723|Acidobacteria,2JN5T@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
TH3_k127_8602029_0	1267534.KB906754_gene3773	3.354e-293	915.0	COG1009@1|root,COG1009@2|Bacteria,3Y76V@57723|Acidobacteria,2JMJJ@204432|Acidobacteriia	204432|Acidobacteriia	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
TH3_k127_8602029_5	1267534.KB906754_gene3772	1.18e-207	660.0	COG1008@1|root,COG1008@2|Bacteria,3Y6ZF@57723|Acidobacteria,2JMB1@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TH3_k127_8602029_22	103690.17132598	0.0001602	52.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G3GI@1117|Cyanobacteria,1HM4X@1161|Nostocales	1117|Cyanobacteria	CT	Ntpase (Nacht family)	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
TH3_k127_8602029_3	1267534.KB906754_gene3771	1.004e-224	706.0	COG1008@1|root,COG1008@2|Bacteria,3Y6FA@57723|Acidobacteria,2JM6J@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TH3_k127_8602029_7	1267534.KB906754_gene3770	1.496e-171	552.0	COG1007@1|root,COG1007@2|Bacteria,3Y73U@57723|Acidobacteria,2JMM8@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TH3_k127_8602029_21	86106.I862_01655	7.955e-10	69.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,47F1D@766|Rickettsiales	766|Rickettsiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
TH3_k127_8602029_9	1403819.BATR01000092_gene2754	1.43e-131	431.0	COG3174@1|root,COG3174@2|Bacteria,46VTJ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
TH3_k127_8602029_10	1340493.JNIF01000003_gene1731	1.001e-126	425.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
TH3_k127_8602029_13	1267535.KB906767_gene4118	1.753e-51	187.0	COG0531@1|root,COG0531@2|Bacteria,3Y3GY@57723|Acidobacteria,2JHIT@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
TH3_k127_860427_12	886293.Sinac_7506	1.274e-09	69.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
TH3_k127_860427_0	497964.CfE428DRAFT_5670	1.989e-210	670.0	COG0405@1|root,COG0405@2|Bacteria,46SGY@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
TH3_k127_860427_2	861299.J421_3611	4.214e-148	481.0	COG1301@1|root,COG1301@2|Bacteria,1ZT91@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sodium:dicarboxylate symporter family	-	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
TH3_k127_860427_8	1382356.JQMP01000004_gene323	5.322e-88	301.0	COG3804@1|root,COG3804@2|Bacteria,2GA3D@200795|Chloroflexi,27YZV@189775|Thermomicrobia	189775|Thermomicrobia	S	Dihydrodipicolinate reductase, N-terminus	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
TH3_k127_860427_10	1396141.BATP01000057_gene2952	8.46e-72	254.0	COG1475@1|root,COG1475@2|Bacteria,46SQ8@74201|Verrucomicrobia,2IU4T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
TH3_k127_860427_7	1414720.CBYM010000003_gene388	3.968e-97	329.0	COG0524@1|root,COG0524@2|Bacteria,1V4QY@1239|Firmicutes,24HRA@186801|Clostridia,36S3G@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
TH3_k127_860427_11	497964.CfE428DRAFT_6518	1.163e-49	193.0	COG0242@1|root,COG0242@2|Bacteria,46SYF@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
TH3_k127_860427_1	344747.PM8797T_13063	2.516e-171	552.0	COG3119@1|root,COG3119@2|Bacteria,2IXUN@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TH3_k127_860427_3	1123242.JH636434_gene3814	2.113e-146	476.0	COG3119@1|root,COG3119@2|Bacteria,2IY75@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
TH3_k127_860427_4	95619.PM1_0204860	4.876e-132	433.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iYL1228.KPN_00280	Aldedh
TH3_k127_860427_13	388467.A19Y_2770	0.0001133	51.0	COG4636@1|root,COG4636@2|Bacteria,1G4JH@1117|Cyanobacteria,1H9Q5@1150|Oscillatoriales	1117|Cyanobacteria	S	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
TH3_k127_860427_5	497964.CfE428DRAFT_4568	8.653e-127	422.0	28MGX@1|root,2ZATZ@2|Bacteria,46TJV@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_860427_9	945713.IALB_0134	4.734e-85	299.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
TH3_k127_860427_6	266834.SM_b21056	1.107e-102	375.0	COG3291@1|root,COG3828@1|root,COG3291@2|Bacteria,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,UnbV_ASPIC,VCBS
TH3_k127_8662227_0	522306.CAP2UW1_1124	9.544e-205	644.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,2VJKF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
TH3_k127_8662227_4	525897.Dbac_1089	1.455e-35	148.0	2E9FY@1|root,333P7@2|Bacteria,1N8S6@1224|Proteobacteria,42XWP@68525|delta/epsilon subdivisions,2WSIE@28221|Deltaproteobacteria,2MFM6@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8662227_6	867900.Celly_2557	0.0002861	52.0	2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,1I5A4@117743|Flavobacteriia,1F9J7@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8662227_3	1121875.KB907547_gene2994	7.496e-53	193.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TH3_k127_8662227_5	1267533.KB906738_gene2202	3.988e-31	130.0	COG2197@1|root,COG2197@2|Bacteria,3Y8R3@57723|Acidobacteria,2JNDY@204432|Acidobacteriia	204432|Acidobacteriia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TH3_k127_8662227_2	330214.NIDE3247	1.829e-60	218.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
TH3_k127_8662227_1	204669.Acid345_1453	3.963e-64	246.0	COG3447@1|root,COG4585@1|root,COG3447@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_3,MASE1,PAS,PAS_3,PAS_4,PAS_9,SpoIIE
TH3_k127_8662227_7	1211777.BN77_p11114	0.0009913	49.0	COG2202@1|root,COG2984@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2984@2|Bacteria,COG4585@2|Bacteria,1R3TZ@1224|Proteobacteria,2U1UX@28211|Alphaproteobacteria,4B83E@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3
TH3_k127_8665847_3	313628.LNTAR_20082	1.635e-126	415.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	yteT	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_8665847_7	180332.JTGN01000003_gene1990	7.164e-79	276.0	COG0407@1|root,COG0407@2|Bacteria,1TW8J@1239|Firmicutes,24BSH@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
TH3_k127_8665847_2	1499967.BAYZ01000152_gene1425	4.689e-170	556.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
TH3_k127_8665847_4	1492737.FEM08_16340	1.758e-123	449.0	COG3345@1|root,COG3345@2|Bacteria	2|Bacteria	G	alpha-galactosidase	rafA	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
TH3_k127_8665847_1	682795.AciX8_2691	9.277e-250	842.0	COG1554@1|root,COG1554@2|Bacteria,3Y42V@57723|Acidobacteria,2JKPE@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
TH3_k127_8665847_9	1122194.AUHU01000009_gene3274	2.973e-35	158.0	COG3387@1|root,COG3387@2|Bacteria,1MW9J@1224|Proteobacteria,1T2G2@1236|Gammaproteobacteria,465X7@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,GDE_C
TH3_k127_8665847_8	595460.RRSWK_04460	1.902e-47	182.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
TH3_k127_8665847_6	1123242.JH636436_gene23	1.562e-85	304.0	COG1335@1|root,COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1335@2|Bacteria,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TH3_k127_8665847_5	1123242.JH636434_gene4791	2.884e-92	324.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_8665847_11	1279038.KB907339_gene1243	0.0002746	48.0	COG2114@1|root,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2TSVT@28211|Alphaproteobacteria,2JUSX@204441|Rhodospirillales	204441|Rhodospirillales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
TH3_k127_8665847_10	1123242.JH636434_gene4702	1.312e-12	75.0	2B9HV@1|root,322W0@2|Bacteria,2IZR4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8665911_0	1215092.PA6_009_00610	7.055e-46	178.0	28JXH@1|root,2ZA3Z@2|Bacteria,1R8CZ@1224|Proteobacteria,1TC26@1236|Gammaproteobacteria,1YJPC@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8670778_1	886293.Sinac_3465	2.284e-169	545.0	COG3356@1|root,COG3356@2|Bacteria,2IXDY@203682|Planctomycetes	203682|Planctomycetes	G	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
TH3_k127_8670778_11	247490.KSU1_C1131	8.832e-58	207.0	COG1881@1|root,COG1881@2|Bacteria,2J1MM@203682|Planctomycetes	203682|Planctomycetes	G	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP,YHYH
TH3_k127_8670778_2	1089547.KB913013_gene1023	1.213e-138	449.0	COG2730@1|root,COG2730@2|Bacteria,4NGAC@976|Bacteroidetes,47MSS@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
TH3_k127_8670778_15	635013.TherJR_0274	1.646e-17	89.0	COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,24MPI@186801|Clostridia,261WW@186807|Peptococcaceae	186801|Clostridia	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
TH3_k127_8670778_6	1210884.HG799466_gene12649	4.446e-104	344.0	COG1131@1|root,COG1131@2|Bacteria,2IY1H@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_8670778_7	1123508.JH636441_gene3735	1.168e-88	314.0	28IKQ@1|root,2Z8MC@2|Bacteria,2IXYY@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
TH3_k127_8670778_0	886293.Sinac_0926	1.363e-212	671.0	COG3119@1|root,COG3119@2|Bacteria,2IXG7@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
TH3_k127_8670778_17	452637.Oter_1161	1.166e-14	83.0	COG4575@1|root,COG4575@2|Bacteria,46WFC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
TH3_k127_8670778_18	278957.ABEA03000005_gene4419	3.617e-10	65.0	COG5393@1|root,COG5393@2|Bacteria,46XW8@74201|Verrucomicrobia,3K8G8@414999|Opitutae	414999|Opitutae	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
TH3_k127_8670778_5	382464.ABSI01000013_gene1799	1.27e-104	356.0	COG2239@1|root,COG2239@2|Bacteria,46S6D@74201|Verrucomicrobia,2IU82@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Divalent cation transporter	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE,MgtE_N
TH3_k127_8670778_16	589865.DaAHT2_0949	3.361e-16	81.0	COG0296@1|root,COG0296@2|Bacteria,1NIZI@1224|Proteobacteria,42WYM@68525|delta/epsilon subdivisions,2WSNX@28221|Deltaproteobacteria,2MMER@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
TH3_k127_8670778_12	314230.DSM3645_05160	1.75e-55	200.0	COG0637@1|root,COG0637@2|Bacteria,2IZIM@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
TH3_k127_8670778_3	452637.Oter_3498	2.619e-135	439.0	COG0216@1|root,COG0216@2|Bacteria,46S6F@74201|Verrucomicrobia,3K794@414999|Opitutae	414999|Opitutae	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TH3_k127_8670778_14	742742.HMPREF9452_01467	7.64e-21	99.0	COG0254@1|root,COG0254@2|Bacteria,2HUWQ@201174|Actinobacteria,4CVW5@84998|Coriobacteriia	84998|Coriobacteriia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
TH3_k127_8670778_10	497964.CfE428DRAFT_3924	7.857e-64	224.0	COG0231@1|root,COG0231@2|Bacteria,46SQH@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
TH3_k127_8670778_13	1279038.KB907348_gene3100	1.171e-39	156.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,2JQWU@204441|Rhodospirillales	204441|Rhodospirillales	O	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
TH3_k127_8670778_4	497964.CfE428DRAFT_5490	9.614e-116	382.0	COG0524@1|root,COG0524@2|Bacteria,46SCP@74201|Verrucomicrobia	74201|Verrucomicrobia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
TH3_k127_8670778_9	497964.CfE428DRAFT_4944	2.342e-71	251.0	COG1136@1|root,COG1136@2|Bacteria,46V6W@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
TH3_k127_8670778_8	497964.CfE428DRAFT_4943	7.377e-83	295.0	COG0577@1|root,COG0577@2|Bacteria,46U6N@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
TH3_k127_8688551_6	866536.Belba_2664	5.954e-12	74.0	COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,47RR5@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TH3_k127_8688551_5	518766.Rmar_0433	3.662e-12	76.0	COG2353@1|root,COG2353@2|Bacteria,4PBAH@976|Bacteroidetes,1FK7G@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TH3_k127_8688551_3	1121374.KB891580_gene1807	1.611e-69	243.0	COG2199@1|root,COG3706@2|Bacteria,1N2X1@1224|Proteobacteria,1SU4M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Carbohydrate-binding family 9	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_2
TH3_k127_8688551_4	1123368.AUIS01000004_gene217	3.257e-45	169.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,2NCB7@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
TH3_k127_8688551_0	497964.CfE428DRAFT_6354	2.821e-92	309.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	ko:K00560,ko:K00943,ko:K01585	ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523	M00053,M00133	R00566,R02094,R02098,R02101	RC00002,RC00219,RC00299,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
TH3_k127_8688551_1	497964.CfE428DRAFT_6353	7.236e-82	281.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.9,4.1.1.19	ko:K00943,ko:K01585	ko00240,ko00330,ko01100,map00240,map00330,map01100	M00053,M00133	R00566,R02094,R02098	RC00002,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
TH3_k127_8688551_2	373903.Hore_16050	2.668e-73	258.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WB29@53433|Halanaerobiales	186801|Clostridia	GK	TIGRFAM ROK family protein	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
TH3_k127_8688551_7	794903.OPIT5_07685	7.494e-05	46.0	COG1533@1|root,COG1533@2|Bacteria,46S99@74201|Verrucomicrobia,3K8PM@414999|Opitutae	414999|Opitutae	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TH3_k127_8693535_0	882378.RBRH_00535	2.058e-112	380.0	COG0308@1|root,COG0308@2|Bacteria,1NQIW@1224|Proteobacteria,2WA6B@28216|Betaproteobacteria,1K252@119060|Burkholderiaceae	28216|Betaproteobacteria	E	beta subunit of N-acylethanolamine-hydrolyzing acid amidase	-	-	-	-	-	-	-	-	-	-	-	-	NAAA-beta,Phospholip_B
TH3_k127_8693535_1	1499967.BAYZ01000012_gene2475	1.62e-74	257.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	ydjG	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0019170,GO:0055114	-	ko:K18471	ko00640,map00640	-	R10718	RC00739	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
TH3_k127_8727412_1	522306.CAP2UW1_0198	1.926e-156	498.0	COG0560@1|root,COG0560@2|Bacteria,1MW38@1224|Proteobacteria,2VN83@28216|Betaproteobacteria	28216|Betaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
TH3_k127_8727412_6	497964.CfE428DRAFT_4864	6.578e-64	227.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8727412_0	886293.Sinac_6489	1.501e-176	595.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
TH3_k127_8727412_8	247490.KSU1_C0483	5.309e-35	144.0	28WIA@1|root,2ZII9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8727412_2	1408433.JHXV01000001_gene670	5.785e-98	342.0	COG1520@1|root,COG3291@1|root,COG5384@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,COG5384@2|Bacteria,4PKTY@976|Bacteroidetes,1IE9N@117743|Flavobacteriia,2PB1T@246874|Cryomorphaceae	976|Bacteroidetes	J	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	PKD,UnbV_ASPIC,VCBS
TH3_k127_8727412_4	234267.Acid_0687	2.099e-78	285.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,3Y6TZ@57723|Acidobacteria	2|Bacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
TH3_k127_8727412_9	485917.Phep_2066	4.796e-20	103.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
TH3_k127_8727412_7	926550.CLDAP_17040	3.684e-56	213.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
TH3_k127_8727412_3	234267.Acid_1327	7.229e-80	285.0	COG0318@1|root,COG0318@2|Bacteria,3Y65U@57723|Acidobacteria	57723|Acidobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
TH3_k127_8727412_5	234267.Acid_1327	1.184e-69	261.0	COG0318@1|root,COG0318@2|Bacteria,3Y65U@57723|Acidobacteria	57723|Acidobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
TH3_k127_8727412_10	742817.HMPREF9449_01242	9.317e-11	73.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,22XN2@171551|Porphyromonadaceae	976|Bacteroidetes	T	Tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
TH3_k127_8727412_11	1506583.JQJY01000007_gene4146	8.349e-08	64.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1HYP9@117743|Flavobacteriia,2NU2K@237|Flavobacterium	976|Bacteroidetes	S	BatD protein	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
TH3_k127_8747095_9	521674.Plim_0006	5.947e-19	91.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_8747095_0	344747.PM8797T_24941	1.928e-222	700.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TH3_k127_8747095_2	497964.CfE428DRAFT_6359	1.808e-121	402.0	COG1104@1|root,COG1104@2|Bacteria,46SFF@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
TH3_k127_8747095_5	197221.22294801	8.57e-74	265.0	COG1051@1|root,COG1194@1|root,COG1051@2|Bacteria,COG1194@2|Bacteria,1G7MC@1117|Cyanobacteria	1117|Cyanobacteria	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
TH3_k127_8747095_3	497964.CfE428DRAFT_4766	6.656e-88	303.0	COG1039@1|root,COG1039@2|Bacteria,46UTB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03471	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
TH3_k127_8747095_1	452637.Oter_0239	9.917e-195	614.0	COG0050@1|root,COG0050@2|Bacteria,46SFG@74201|Verrucomicrobia,3K7E9@414999|Opitutae	414999|Opitutae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
TH3_k127_8747095_12	59374.Fisuc_1277	7.689e-06	53.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
TH3_k127_8747095_7	278957.ABEA03000094_gene4759	2.669e-59	212.0	COG0250@1|root,COG0250@2|Bacteria,46SR6@74201|Verrucomicrobia,3K7UE@414999|Opitutae	414999|Opitutae	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
TH3_k127_8747095_6	1156937.MFUM_210036	1.831e-62	217.0	COG0080@1|root,COG0080@2|Bacteria,46SPZ@74201|Verrucomicrobia,37GN5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
TH3_k127_8747095_4	497964.CfE428DRAFT_5605	9.259e-87	294.0	COG0081@1|root,COG0081@2|Bacteria,46S7K@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
TH3_k127_8747095_8	1403819.BATR01000191_gene6561	3.397e-45	169.0	COG0244@1|root,COG0244@2|Bacteria,46T4Q@74201|Verrucomicrobia,2IUF1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
TH3_k127_8747095_10	1532558.JL39_13770	1.187e-11	66.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria,4BESI@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
TH3_k127_8784914_3	1304885.AUEY01000001_gene3204	1.131e-21	100.0	2DPAK@1|root,33193@2|Bacteria,1NDU6@1224|Proteobacteria,432ZD@68525|delta/epsilon subdivisions,2WYIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8784914_4	579137.Metvu_0192	2.127e-20	100.0	COG0655@1|root,arCOG02573@2157|Archaea,2XVMU@28890|Euryarchaeota,23QEP@183939|Methanococci	183939|Methanococci	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
TH3_k127_8784914_2	596151.DesfrDRAFT_0880	7.483e-36	144.0	COG4273@1|root,COG4273@2|Bacteria,1MZED@1224|Proteobacteria,42UH2@68525|delta/epsilon subdivisions,2WQNQ@28221|Deltaproteobacteria,2MBB6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	DGC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DGC
TH3_k127_8784914_5	398767.Glov_1181	3.674e-14	84.0	COG1146@1|root,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	fdxB	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7
TH3_k127_8784914_0	909663.KI867150_gene1425	4.836e-101	333.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria,2MS43@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
TH3_k127_8784914_1	795359.TOPB45_0891	1.037e-79	276.0	COG2191@1|root,COG2191@2|Bacteria	2|Bacteria	C	Formylmethanofuran dehydrogenase, subunit e	-	-	-	-	-	-	-	-	-	-	-	-	FmdE
TH3_k127_8784914_6	1121439.dsat_1022	1.731e-11	67.0	COG1246@1|root,COG1246@2|Bacteria,1R0RF@1224|Proteobacteria,43D0Y@68525|delta/epsilon subdivisions,2X88U@28221|Deltaproteobacteria,2MHDF@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM C_GCAxxG_C_C family protein	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
TH3_k127_8796561_15	215803.DB30_8826	2.401e-16	80.0	28H95@1|root,2Z7KY@2|Bacteria,1RA0C@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
TH3_k127_8796561_11	452637.Oter_1160	2.064e-50	184.0	28H95@1|root,2Z7KY@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
TH3_k127_8796561_7	1123242.JH636434_gene3764	5.758e-114	383.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_8796561_9	1123242.JH636435_gene2613	3.537e-60	216.0	COG1595@1|root,COG1595@2|Bacteria,2IZZP@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
TH3_k127_8796561_4	1396141.BATP01000060_gene4560	2.634e-170	583.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
TH3_k127_8796561_8	1097668.BYI23_C006580	1.594e-93	323.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	msrB	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,PMSR,Redoxin,SelR,Thioredoxin
TH3_k127_8796561_12	344747.PM8797T_14579	3.447e-49	180.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TH3_k127_8796561_1	497964.CfE428DRAFT_1053	3.886e-236	744.0	COG1574@1|root,COG1574@2|Bacteria,46V0N@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
TH3_k127_8796561_3	1123508.JH636439_gene1370	5.079e-193	622.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
TH3_k127_8796561_10	1396141.BATP01000022_gene421	1.018e-57	214.0	2BVGP@1|root,32QVG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8796561_2	1123073.KB899241_gene3060	2.794e-193	615.0	COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria,1XDA0@135614|Xanthomonadales	135614|Xanthomonadales	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	ko:K08137	-	-	-	-	ko00000,ko02000	2.A.1.1.1	-	-	Sugar_tr
TH3_k127_8796561_6	1499967.BAYZ01000164_gene6663	7.527e-152	494.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
TH3_k127_8796561_5	497964.CfE428DRAFT_3605	6.003e-167	539.0	COG0364@1|root,COG0364@2|Bacteria,46SHX@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
TH3_k127_8796561_14	378806.STAUR_7040	1.986e-26	118.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42UV6@68525|delta/epsilon subdivisions,2WP1R@28221|Deltaproteobacteria,2YVX1@29|Myxococcales	28221|Deltaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
TH3_k127_8796561_0	314230.DSM3645_01876	9.8e-244	781.0	COG0308@1|root,COG0308@2|Bacteria,2IY5F@203682|Planctomycetes	203682|Planctomycetes	M	Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
TH3_k127_8796561_13	592010.GCWU000182_000717	4.104e-34	142.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,27DGV@186827|Aerococcaceae	91061|Bacilli	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TH3_k127_8860588_20	382464.ABSI01000013_gene1636	6.509e-25	108.0	COG0123@1|root,COG0123@2|Bacteria,46SMT@74201|Verrucomicrobia,2IUMK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
TH3_k127_8860588_10	452637.Oter_4549	2.639e-110	366.0	28JIN@1|root,30U02@2|Bacteria,46YTT@74201|Verrucomicrobia,3K7XH@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8860588_24	1396141.BATP01000023_gene664	7.406e-17	94.0	COG2931@1|root,COG3266@1|root,COG4733@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB,DUF1499,Flg_new
TH3_k127_8860588_28	497964.CfE428DRAFT_5963	5.293e-12	78.0	2F7AY@1|root,33ZS4@2|Bacteria,46VZW@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8860588_15	497964.CfE428DRAFT_3022	2.959e-35	138.0	COG2363@1|root,COG2363@2|Bacteria,46T86@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
TH3_k127_8860588_19	497964.CfE428DRAFT_4380	3.032e-25	113.0	COG1664@1|root,COG1664@2|Bacteria,46WDW@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
TH3_k127_8860588_18	497964.CfE428DRAFT_4379	1.275e-26	116.0	COG1664@1|root,COG1664@2|Bacteria,46VS6@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
TH3_k127_8860588_12	886293.Sinac_3711	2.206e-97	330.0	COG2896@1|root,COG2896@2|Bacteria,2IXWS@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
TH3_k127_8860588_17	452637.Oter_2046	8.709e-27	118.0	COG0466@1|root,COG0466@2|Bacteria,46WE2@74201|Verrucomicrobia,3K9NW@414999|Opitutae	414999|Opitutae	O	PFAM peptidase S16 lon domain protein	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
TH3_k127_8860588_29	1265505.ATUG01000001_gene3561	1.709e-10	68.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2MKY4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
TH3_k127_8860588_16	1476973.JMMB01000007_gene3240	2.722e-34	146.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,24C7H@186801|Clostridia,25UIJ@186804|Peptostreptococcaceae	186801|Clostridia	M	SurA N-terminal domain	prsA	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
TH3_k127_8860588_5	497964.CfE428DRAFT_5481	4.819e-164	532.0	COG1052@1|root,COG1052@2|Bacteria,46SAN@74201|Verrucomicrobia	74201|Verrucomicrobia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
TH3_k127_8860588_2	243233.MCA2161	2.548e-168	553.0	COG3206@1|root,COG3206@2|Bacteria,1QX0J@1224|Proteobacteria,1RZ5A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8860588_26	1040989.AWZU01000025_gene6324	2.459e-14	87.0	COG2335@1|root,COG2335@2|Bacteria,1MZ8G@1224|Proteobacteria,2U5ZN@28211|Alphaproteobacteria,3JY4R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
TH3_k127_8860588_4	289376.THEYE_A0114	1.265e-166	531.0	COG0473@1|root,COG0473@2|Bacteria,3J0JQ@40117|Nitrospirae	40117|Nitrospirae	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
TH3_k127_8860588_25	313628.LNTAR_07769	7.923e-15	86.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_8860588_7	497964.CfE428DRAFT_5370	3.317e-147	473.0	COG2255@1|root,COG2255@2|Bacteria,46SDS@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
TH3_k127_8860588_0	234267.Acid_0830	8.023e-241	759.0	COG2936@1|root,COG2936@2|Bacteria,3Y2WR@57723|Acidobacteria	57723|Acidobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
TH3_k127_8860588_8	190650.CC_3489	2.524e-133	444.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2VF1X@28211|Alphaproteobacteria,2KK2H@204458|Caulobacterales	204458|Caulobacterales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TH3_k127_8860588_30	1173026.Glo7428_0087	1.963e-06	51.0	COG0265@1|root,COG0265@2|Bacteria,1G3M4@1117|Cyanobacteria	1117|Cyanobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
TH3_k127_8860588_22	1123508.JH636439_gene1125	3.005e-24	117.0	COG0457@1|root,COG0457@2|Bacteria	1123508.JH636439_gene1125|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8860588_9	251221.35212674	7.882e-122	403.0	COG0265@1|root,COG0265@2|Bacteria,1G3M4@1117|Cyanobacteria	1117|Cyanobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
TH3_k127_8860588_27	700598.Niako_1079	1.693e-12	72.0	COG1403@1|root,COG1479@1|root,COG1403@2|Bacteria,COG1479@2|Bacteria,4NHK1@976|Bacteroidetes,1J0FS@117747|Sphingobacteriia	976|Bacteroidetes	L	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
TH3_k127_8860588_21	552811.Dehly_1587	2.015e-24	111.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi,34D41@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
TH3_k127_8860588_11	497964.CfE428DRAFT_2614	7.144e-104	346.0	COG4989@1|root,COG4989@2|Bacteria,46SU2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TH3_k127_8860588_31	158787.BSCA_0674	8.644e-05	55.0	COG5305@1|root,COG5305@2|Bacteria,2HZBN@201174|Actinobacteria,4CZKJ@85004|Bifidobacteriales	201174|Actinobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TH3_k127_8860588_6	649638.Trad_2705	7.725e-148	486.0	COG0382@1|root,COG0546@1|root,COG0382@2|Bacteria,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD,UbiA
TH3_k127_8860588_23	1173028.ANKO01000193_gene5881	1.937e-17	97.0	2DJZT@1|root,32UE2@2|Bacteria,1G8K4@1117|Cyanobacteria,1HCD2@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8860588_1	1173028.ANKO01000193_gene5880	1.761e-207	669.0	COG2303@1|root,COG2303@2|Bacteria,1G3V7@1117|Cyanobacteria,1H9T9@1150|Oscillatoriales	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
TH3_k127_8860588_3	1173028.ANKO01000193_gene5879	1.169e-166	529.0	COG0451@1|root,COG0451@2|Bacteria,1G3T6@1117|Cyanobacteria,1HA43@1150|Oscillatoriales	1117|Cyanobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TH3_k127_8925946_2	156889.Mmc1_2548	3.874e-94	319.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
TH3_k127_8925946_11	411473.RUMCAL_00366	2.618e-17	89.0	2F26G@1|root,33V4S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8925946_15	199310.c3384	1.073e-08	57.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,1RP7K@1236|Gammaproteobacteria,3XMK4@561|Escherichia	1236|Gammaproteobacteria	M	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division	mltA	GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016787,GO:0016798,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	iECABU_c1320.ECABU_c30840	3D,MltA
TH3_k127_8925946_1	234267.Acid_4959	7.222e-108	379.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y63K@57723|Acidobacteria	57723|Acidobacteria	T	ATP-binding region, ATPase domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
TH3_k127_8925946_0	497964.CfE428DRAFT_0970	1.345e-249	793.0	COG0457@1|root,COG0457@2|Bacteria,46UPB@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1,TPR_8
TH3_k127_8925946_8	671143.DAMO_1689	2.969e-31	131.0	COG4309@1|root,COG4309@2|Bacteria	2|Bacteria	D	conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,DUF2249
TH3_k127_8925946_4	671143.DAMO_1688	6.373e-80	285.0	COG3278@1|root,COG3278@2|Bacteria,2NRHY@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8925946_9	1051632.TPY_0746	1.347e-30	126.0	COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,24VD9@186801|Clostridia	186801|Clostridia	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
TH3_k127_8925946_10	278957.ABEA03000176_gene2840	5.885e-25	107.0	COG4309@1|root,COG4309@2|Bacteria,46XTU@74201|Verrucomicrobia,3K814@414999|Opitutae	414999|Opitutae	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
TH3_k127_8925946_7	392500.Swoo_0456	9.391e-44	173.0	COG4783@1|root,COG4783@2|Bacteria,1QV70@1224|Proteobacteria,1RQJV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TH3_k127_8925946_12	382464.ABSI01000013_gene1773	4.782e-11	76.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8925946_13	497964.CfE428DRAFT_3795	1.014e-09	72.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8925946_3	404589.Anae109_3548	4.759e-90	338.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1REF1@1224|Proteobacteria,42RS0@68525|delta/epsilon subdivisions,2WNDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
TH3_k127_8925946_6	497964.CfE428DRAFT_5270	5.95e-73	251.0	COG1187@1|root,COG1187@2|Bacteria,46V8C@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
TH3_k127_8925946_5	1397666.RS24_01915	2.605e-75	266.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2TRMU@28211|Alphaproteobacteria,4BPNB@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	NU	Type II/IV secretion system protein	gspE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
TH3_k127_8925946_14	62928.azo2096	1.829e-09	69.0	COG1459@1|root,COG1459@2|Bacteria,1N8FA@1224|Proteobacteria,2VJ0W@28216|Betaproteobacteria,2KV1F@206389|Rhodocyclales	206389|Rhodocyclales	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
TH3_k127_8955576_3	344747.PM8797T_08389	8.071e-09	56.0	COG1520@1|root,COG1520@2|Bacteria,2IWVH@203682|Planctomycetes	203682|Planctomycetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8955576_0	497964.CfE428DRAFT_3502	2.023e-285	909.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46THN@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TH3_k127_8955576_1	1168034.FH5T_08245	5.748e-65	235.0	COG0667@1|root,COG0667@2|Bacteria,4PPAM@976|Bacteroidetes,2G14T@200643|Bacteroidia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TH3_k127_8955576_2	616991.JPOO01000003_gene1304	2.191e-52	191.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1HXZD@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31,PA14
TH3_k127_8957788_23	395495.Lcho_0773	4.098e-05	46.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,2VHUB@28216|Betaproteobacteria,1KPAP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
TH3_k127_8957788_0	497964.CfE428DRAFT_3903	1.663e-163	532.0	COG1640@1|root,COG1640@2|Bacteria,46SX0@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM glycoside hydrolase family 77	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
TH3_k127_8957788_4	756067.MicvaDRAFT_5451	1.663e-91	335.0	COG1361@1|root,COG2931@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1G463@1117|Cyanobacteria,1H97Y@1150|Oscillatoriales	1117|Cyanobacteria	MQ	PFAM Collagen-binding surface protein Cna-like, B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,SdrD_B
TH3_k127_8957788_2	1379698.RBG1_1C00001G1529	3.644e-99	340.0	COG2304@1|root,COG2304@2|Bacteria,2NPUS@2323|unclassified Bacteria	2|Bacteria	S	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
TH3_k127_8957788_11	478741.JAFS01000002_gene501	2.143e-47	187.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	MFS_1
TH3_k127_8957788_16	1123401.JHYQ01000003_gene2070	5.348e-31	143.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,1RSEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
TH3_k127_8957788_13	99598.Cal7507_0707	3.344e-36	158.0	COG4102@1|root,COG4102@2|Bacteria,1G2W5@1117|Cyanobacteria,1HM3H@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TH3_k127_8957788_17	760192.Halhy_1586	7.711e-21	104.0	COG2931@1|root,COG2931@2|Bacteria,4NKF1@976|Bacteroidetes,1IVE6@117747|Sphingobacteriia	976|Bacteroidetes	Q	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,SusE
TH3_k127_8957788_5	1123508.JH636452_gene6946	3.8e-88	309.0	COG1520@1|root,COG1520@2|Bacteria,2IYAV@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_8957788_7	290397.Adeh_1286	2.07e-70	245.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,43EF3@68525|delta/epsilon subdivisions,2X0ID@28221|Deltaproteobacteria,2Z1N2@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TH3_k127_8957788_14	1396418.BATQ01000049_gene401	2.056e-35	142.0	COG3654@1|root,COG3654@2|Bacteria	2|Bacteria	-	-	doc	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
TH3_k127_8957788_1	929562.Emtol_1353	7.227e-159	518.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
TH3_k127_8957788_10	452637.Oter_0714	6.275e-59	211.0	COG1595@1|root,COG1639@1|root,COG1595@2|Bacteria,COG1639@2|Bacteria	2|Bacteria	T	HDOD domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	HDOD,Sigma70_r2,Sigma70_r4_2
TH3_k127_8957788_8	452637.Oter_0712	8.226e-63	237.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
TH3_k127_8957788_21	886293.Sinac_0920	3.682e-13	75.0	COG0673@1|root,COG0673@2|Bacteria,2IWZW@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_8957788_3	118166.JH976538_gene5057	2.475e-92	327.0	COG4191@1|root,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,Response_reg
TH3_k127_8957788_6	497964.CfE428DRAFT_2060	7.402e-75	263.0	COG0142@1|root,COG0142@2|Bacteria,46SKW@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
TH3_k127_8957788_9	240016.ABIZ01000001_gene3616	1.769e-59	214.0	COG1595@1|root,COG1595@2|Bacteria,46SWN@74201|Verrucomicrobia,2IUE1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TH3_k127_8957788_15	269798.CHU_0700	9.921e-35	138.0	COG2010@1|root,COG2010@2|Bacteria,4NQN1@976|Bacteroidetes,47XSN@768503|Cytophagia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
TH3_k127_8957788_12	1165841.SULAR_01175	6.669e-42	162.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,42TZV@68525|delta/epsilon subdivisions,2YR1J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
TH3_k127_8957788_22	1303518.CCALI_01450	3.888e-11	74.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_8957788_20	864051.BurJ1DRAFT_0942	1.068e-13	82.0	COG1520@1|root,COG1520@2|Bacteria,1P0W9@1224|Proteobacteria	1224|Proteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8957788_18	742725.HMPREF9450_01532	1.557e-20	97.0	COG3420@1|root,COG3420@2|Bacteria,4PMG9@976|Bacteroidetes,2FQGR@200643|Bacteroidia	976|Bacteroidetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TH3_k127_8959676_5	1237149.C900_03088	5.835e-43	164.0	2E3CB@1|root,32YBM@2|Bacteria,4PPUF@976|Bacteroidetes	2|Bacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
TH3_k127_8959676_2	497964.CfE428DRAFT_4749	6.647e-104	369.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K13598,ko:K13924	ko02020,ko02030,map02020,map02030	M00498,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	ABC_sub_bind,CHASE4,GAF,HAMP,HATPase_c,HDOD,HisKA,PAS,PAS_3,PAS_4,PAS_9
TH3_k127_8959676_0	497964.CfE428DRAFT_4750	4.515e-201	648.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
TH3_k127_8959676_1	452637.Oter_2706	4.168e-194	613.0	COG0148@1|root,COG0148@2|Bacteria,46S7N@74201|Verrucomicrobia,3K7NC@414999|Opitutae	414999|Opitutae	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
TH3_k127_8959676_8	1396141.BATP01000029_gene2250	9.194e-16	90.0	COG1525@1|root,COG1525@2|Bacteria,46WA1@74201|Verrucomicrobia,2IWGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_8959676_9	159087.Daro_0466	3.186e-05	46.0	COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,2VVT0@28216|Betaproteobacteria,2KXPG@206389|Rhodocyclales	206389|Rhodocyclales	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
TH3_k127_8959676_3	452637.Oter_4547	1.932e-49	179.0	COG0239@1|root,COG0239@2|Bacteria,46W5U@74201|Verrucomicrobia,3K8J7@414999|Opitutae	414999|Opitutae	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
TH3_k127_8959676_4	452637.Oter_4548	3.225e-48	174.0	COG1993@1|root,COG1993@2|Bacteria,46VZM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
TH3_k127_8959676_6	1499967.BAYZ01000068_gene1988	5.261e-37	154.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_8959676_7	391603.FBALC1_09677	3.811e-21	109.0	COG2706@1|root,COG4886@1|root,COG2706@2|Bacteria,COG4886@2|Bacteria,4NFXV@976|Bacteroidetes,1I00F@117743|Flavobacteriia	976|Bacteroidetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TH3_k127_8961859_0	1403819.BATR01000007_gene203	4.608e-269	863.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,DUF1080,GSDH,HEAT_2,Laminin_G_3,Lipase_GDSL_2,ThuA
TH3_k127_8961859_2	497964.CfE428DRAFT_2729	5.005e-74	257.0	COG1209@1|root,COG1209@2|Bacteria,46T9Q@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Nucleotidyl transferase	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TH3_k127_8961859_6	1123247.AUIJ01000005_gene313	2.267e-29	130.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TH3_k127_8961859_10	324602.Caur_0299	3.475e-11	75.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
TH3_k127_8961859_8	870187.Thini_1532	2.904e-17	94.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin,Cadherin_3,Calx-beta,DUF4347,He_PIG,Invasin_D3,Laminin_G_3,Lectin_C,PA14,Pentaxin,Peptidase_S74
TH3_k127_8961859_11	316274.Haur_2191	5.917e-10	66.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	2.7.11.1	ko:K11904,ko:K12132	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02044	3.A.23.1	-	-	DUF1565,DUF3494,Pkinase,SLH,TadE
TH3_k127_8961859_1	481448.Minf_1814	3.136e-261	823.0	COG0556@1|root,COG0556@2|Bacteria,46SF2@74201|Verrucomicrobia,37GG7@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
TH3_k127_8961859_5	997346.HMPREF9374_0351	4.48e-41	164.0	COG1597@1|root,COG1597@2|Bacteria,1TQJH@1239|Firmicutes,4HJ8D@91061|Bacilli,27BZ5@186824|Thermoactinomycetaceae	91061|Bacilli	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
TH3_k127_8961859_3	472759.Nhal_3844	3.432e-64	226.0	COG0500@1|root,COG2226@2|Bacteria,1RDI3@1224|Proteobacteria,1S423@1236|Gammaproteobacteria,1WWQ9@135613|Chromatiales	135613|Chromatiales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
TH3_k127_8961859_4	1125863.JAFN01000001_gene972	2.923e-41	162.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
TH3_k127_8961859_9	1340493.JNIF01000003_gene4360	3.964e-16	88.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM60,Cu-binding_MopE,DUF4214,Peptidase_M10,Peptidase_S8
TH3_k127_8961859_7	1385935.N836_16170	1.527e-18	90.0	COG4974@1|root,COG4974@2|Bacteria,1G224@1117|Cyanobacteria,1H8SW@1150|Oscillatoriales	1117|Cyanobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
TH3_k127_8963046_0	456442.Mboo_0327	0.0	1165.0	COG2201@1|root,arCOG02354@1|root,arCOG02354@2157|Archaea,arCOG04921@2157|Archaea,2Y7RM@28890|Euryarchaeota,2N9F6@224756|Methanomicrobia	224756|Methanomicrobia	N	PAS domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS,PAS_10,PAS_4
TH3_k127_8963046_4	313624.NSP_48390	5.457e-36	160.0	COG2202@1|root,COG2203@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1HKMC@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4
TH3_k127_8963046_2	1121413.JMKT01000008_gene1013	9.6e-62	245.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2MH9G@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
TH3_k127_8963046_1	335543.Sfum_0581	4.661e-93	347.0	COG2202@1|root,COG2984@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2984@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS_3
TH3_k127_8963046_3	443598.AUFA01000003_gene2204	3.884e-59	213.0	COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,2TSQS@28211|Alphaproteobacteria,3JQPG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TH3_k127_8963046_5	1037409.BJ6T_24560	7.406e-22	100.0	COG4566@1|root,COG4566@2|Bacteria,1N5R5@1224|Proteobacteria,2UE41@28211|Alphaproteobacteria,3K0DI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TH3_k127_8963046_6	90813.JQMT01000001_gene1896	5.911e-07	59.0	COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria,1RQKS@1236|Gammaproteobacteria,462JF@72273|Thiotrichales	72273|Thiotrichales	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
TH3_k127_8968938_0	1254432.SCE1572_17235	0.0	1227.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TH3_k127_8970608_0	1122176.KB903598_gene4625	0.0	1116.0	COG3321@1|root,COG3321@2|Bacteria,4PKD5@976|Bacteroidetes,1IPC0@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
TH3_k127_8970608_2	1173028.ANKO01000220_gene563	7.051e-205	656.0	COG0236@1|root,COG0318@1|root,COG0236@2|Bacteria,COG0318@2|Bacteria,1G4CE@1117|Cyanobacteria,1HHT8@1150|Oscillatoriales	1117|Cyanobacteria	IQ	AMP-dependent synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding,Thioesterase
TH3_k127_8970608_4	1382306.JNIM01000001_gene377	5.548e-44	167.0	COG2185@1|root,COG2185@2|Bacteria,2G6S9@200795|Chloroflexi	200795|Chloroflexi	I	PFAM cobalamin B12-binding domain protein	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
TH3_k127_8970608_1	1123405.AUMM01000010_gene1224	2.338e-214	676.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,26P9A@186821|Sporolactobacillaceae	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
TH3_k127_8970608_3	391623.TERMP_01057	2.506e-44	164.0	COG0346@1|root,arCOG02706@2157|Archaea,2XY0R@28890|Euryarchaeota,24458@183968|Thermococci	183968|Thermococci	E	Glyoxalase-like domain	-	GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
TH3_k127_8970608_7	522306.CAP2UW1_0407	4.41e-05	51.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,2VMZ8@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
TH3_k127_8970608_5	1340493.JNIF01000003_gene2050	4.621e-29	122.0	COG3436@1|root,COG3436@2|Bacteria	2|Bacteria	L	PFAM IS66 Orf2 family protein	tnpB	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
TH3_k127_8970608_6	1125863.JAFN01000001_gene1845	2.613e-06	56.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,43BUU@68525|delta/epsilon subdivisions,2WKYP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TH3_k127_9005924_2	1198114.AciX9_2572	1.032e-24	107.0	COG3344@1|root,COG3344@2|Bacteria,3Y46K@57723|Acidobacteria,2JJPA@204432|Acidobacteriia	204432|Acidobacteriia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1,RVT_N
TH3_k127_9005924_0	237609.PSAKL28_31720	5.733e-286	895.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,1RZMQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TH3_k127_9005924_1	391038.Bphy_7464	1.679e-82	286.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VKHY@28216|Betaproteobacteria,1JZQ8@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Group II intron, maturase-specific domain	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
TH3_k127_9005924_3	706587.Desti_2842	1.822e-15	79.0	2EUYT@1|root,33NE0@2|Bacteria,1P79U@1224|Proteobacteria,432X2@68525|delta/epsilon subdivisions,2WXB8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9042438_2	537013.CLOSTMETH_03549	2.334e-30	126.0	COG1196@1|root,COG3250@1|root,COG3669@1|root,COG1196@2|Bacteria,COG3250@2|Bacteria,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	sca1	-	3.2.1.51	ko:K01206,ko:K21449	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko02000,ko04147	1.B.40.2	GH29	-	Alpha_L_fucos,DUF4988,F5_F8_type_C,FIVAR,Glyco_hydro_106,Glyco_hydro_2_N,RicinB_lectin_2
TH3_k127_9042438_0	595460.RRSWK_03373	7.611e-285	896.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Beta_helix,PDZ_2,PEGA,Trypsin_2
TH3_k127_9042438_3	497964.CfE428DRAFT_6536	6.681e-09	61.0	COG0657@1|root,COG0657@2|Bacteria,46TYV@74201|Verrucomicrobia	2|Bacteria	CI	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase,Lipase_GDSL_2,Peptidase_S9
TH3_k127_9042438_1	661478.OP10G_0590	7.888e-34	138.0	COG3940@1|root,COG3940@2|Bacteria	2|Bacteria	G	arabinan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N,Glyco_hydro_43,Laminin_G_3
TH3_k127_9058526_1	1297742.A176_06501	1.735e-47	198.0	COG2204@1|root,COG3292@1|root,COG4191@1|root,COG2204@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42Q3F@68525|delta/epsilon subdivisions,2WM2F@28221|Deltaproteobacteria,2YUEQ@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
TH3_k127_9058526_0	102125.Xen7305DRAFT_00020060	9.512e-53	216.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CW_binding_1,VCBS
TH3_k127_9058764_1	1232410.KI421426_gene1466	1.07e-19	95.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,43UJP@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HTH_8,PAS_3,PAS_4,Sigma54_activat
TH3_k127_9058764_0	1121456.ATVA01000013_gene930	4.805e-39	145.0	COG1961@1|root,COG1961@2|Bacteria,1RAYT@1224|Proteobacteria,43AVZ@68525|delta/epsilon subdivisions,2X6A5@28221|Deltaproteobacteria,2MH0P@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9138039_1	236097.ADG881_431	7.173e-81	309.0	COG3391@1|root,COG4733@1|root,COG3391@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	-
TH3_k127_9138039_10	400682.PAC_15716390	0.0008479	54.0	2DZK8@1|root,2S73K@2759|Eukaryota,3AA3U@33154|Opisthokonta,3BU2C@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TH3_k127_9138039_2	1121920.AUAU01000009_gene1881	6.157e-66	260.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
TH3_k127_9138039_5	926560.KE387023_gene2150	1.755e-46	196.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4347,He_PIG,HemolysinCabind,RCC1_2
TH3_k127_9138039_7	794903.OPIT5_07325	1.499e-18	92.0	COG0499@1|root,COG0499@2|Bacteria,46SGX@74201|Verrucomicrobia,3K76U@414999|Opitutae	414999|Opitutae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
TH3_k127_9138039_9	1120949.KB903306_gene7572	1.103e-05	59.0	COG1361@1|root,COG2304@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,2I8F1@201174|Actinobacteria,4DFBB@85008|Micromonosporales	201174|Actinobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF3344
TH3_k127_9138039_6	383372.Rcas_0336	5.561e-25	122.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
TH3_k127_9138039_8	935863.AWZR01000007_gene245	2.068e-11	67.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1X33V@135614|Xanthomonadales	135614|Xanthomonadales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
TH3_k127_9138039_3	452637.Oter_0623	2.064e-55	199.0	COG3428@1|root,COG3428@2|Bacteria,46VXR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
TH3_k127_9138039_4	452637.Oter_0624	1.331e-47	183.0	COG3428@1|root,COG3428@2|Bacteria,46VTZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
TH3_k127_9138039_0	278957.ABEA03000091_gene684	2.311e-127	409.0	COG0499@1|root,COG0499@2|Bacteria,46SGX@74201|Verrucomicrobia,3K76U@414999|Opitutae	414999|Opitutae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
TH3_k127_9142466_1	1121924.ATWH01000017_gene3159	3.461e-44	178.0	COG3408@1|root,COG3408@2|Bacteria,2GYU2@201174|Actinobacteria,4FR4D@85023|Microbacteriaceae	201174|Actinobacteria	G	Glycosyl-hydrolase family 116, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DUF608
TH3_k127_9142466_0	1123242.JH636434_gene3911	4.844e-128	420.0	COG1957@1|root,COG1957@2|Bacteria,2IYE3@203682|Planctomycetes	203682|Planctomycetes	F	COG1957 Inosine-uridine nucleoside N-ribohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
TH3_k127_9142466_2	1121904.ARBP01000013_gene373	3.898e-41	168.0	COG2730@1|root,COG2730@2|Bacteria,4P1NI@976|Bacteroidetes,47TT8@768503|Cytophagia	976|Bacteroidetes	G	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
TH3_k127_9154801_5	481448.Minf_0089	5.93e-16	91.0	2ADRD@1|root,313GQ@2|Bacteria,46ZIR@74201|Verrucomicrobia,37GDJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
TH3_k127_9154801_0	497964.CfE428DRAFT_3562	5.337e-129	424.0	COG1459@1|root,COG1459@2|Bacteria,46S5B@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
TH3_k127_9154801_1	1499967.BAYZ01000088_gene5090	1.052e-110	367.0	COG0191@1|root,COG0191@2|Bacteria,2NPSG@2323|unclassified Bacteria	2|Bacteria	G	Fructose-bisphosphate aldolase class-II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
TH3_k127_9154801_2	497964.CfE428DRAFT_3685	5.498e-44	165.0	COG0071@1|root,COG0071@2|Bacteria,46T3G@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Belongs to the small heat shock protein (HSP20) family	ibpA	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
TH3_k127_9154801_4	497964.CfE428DRAFT_3684	4.488e-30	124.0	COG0071@1|root,COG0071@2|Bacteria,46WRX@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
TH3_k127_9154801_6	1210884.HG799466_gene12517	9.608e-12	75.0	COG4968@1|root,COG4968@2|Bacteria,2J4X1@203682|Planctomycetes	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_9166233_1	240016.ABIZ01000001_gene5593	4.41e-15	78.0	COG3378@1|root,COG3378@2|Bacteria	2|Bacteria	KL	Phage plasmid primase P4 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,P22_AR_N,PriCT_1,Prim-Pol
TH3_k127_9166233_0	261292.Nit79A3_0138	3.564e-131	427.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_32
TH3_k127_9166233_2	1242864.D187_000130	3.174e-12	78.0	COG2273@1|root,COG2730@1|root,COG2273@2|Bacteria,COG2730@2|Bacteria,1P6R4@1224|Proteobacteria	1224|Proteobacteria	G	Hydrolase Family 16	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9168406_8	641524.ADICYQ_2925	5.568e-39	149.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,47ME7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_9168406_9	925775.XVE_1359	0.0004207	45.0	2CA82@1|root,2ZP0Q@2|Bacteria,1NDH6@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF3658
TH3_k127_9168406_1	497964.CfE428DRAFT_1842	3.535e-154	490.0	COG1082@1|root,COG1082@2|Bacteria,46U2S@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TH3_k127_9168406_4	1550091.JROE01000002_gene502	8.12e-94	323.0	2DBWR@1|root,2ZBIN@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
TH3_k127_9168406_2	497964.CfE428DRAFT_6195	5.502e-142	460.0	COG0673@1|root,COG0673@2|Bacteria,46UE3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_9168406_0	33876.JNXY01000025_gene5296	9.19e-197	623.0	COG4225@1|root,COG4225@2|Bacteria,2I2TJ@201174|Actinobacteria,4DGGH@85008|Micromonosporales	201174|Actinobacteria	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
TH3_k127_9168406_5	794903.OPIT5_16130	7.436e-93	314.0	COG1028@1|root,COG1028@2|Bacteria,46TD2@74201|Verrucomicrobia,3K7W5@414999|Opitutae	414999|Opitutae	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TH3_k127_9168406_3	696369.KI912183_gene1481	4.339e-104	349.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,25ZZM@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
TH3_k127_9168406_7	452637.Oter_4555	5.086e-55	198.0	2C0ZJ@1|root,33VV4@2|Bacteria,46VGY@74201|Verrucomicrobia,3K7JZ@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9168406_6	469383.Cwoe_4579	3.013e-60	218.0	COG1994@1|root,COG1994@2|Bacteria,2H6BD@201174|Actinobacteria,4CS7E@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9183203_7	497964.CfE428DRAFT_3455	8.735e-23	102.0	COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	2.3.1.241	ko:K02517,ko:K02843	ko00540,ko01100,map00540,map01100	M00060,M00080	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Lip_A_acyltrans
TH3_k127_9183203_5	497964.CfE428DRAFT_3455	2.297e-40	164.0	COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	2.3.1.241	ko:K02517,ko:K02843	ko00540,ko01100,map00540,map01100	M00060,M00080	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Lip_A_acyltrans
TH3_k127_9183203_3	1156937.MFUM_690053	1.168e-118	392.0	COG1663@1|root,COG1663@2|Bacteria,46SBI@74201|Verrucomicrobia,37G5N@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
TH3_k127_9183203_1	344747.PM8797T_07534	4.286e-175	561.0	COG1073@1|root,COG1073@2|Bacteria,2IWT8@203682|Planctomycetes	203682|Planctomycetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9183203_4	497964.CfE428DRAFT_2711	4.357e-89	310.0	COG0544@1|root,COG0544@2|Bacteria,46SJZ@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
TH3_k127_9183203_6	710696.Intca_1127	1.735e-26	125.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR,BNR_2,DUF11,SBBP
TH3_k127_9183203_0	497964.CfE428DRAFT_5484	4.846e-178	579.0	COG0323@1|root,COG0323@2|Bacteria,46SG5@74201|Verrucomicrobia	74201|Verrucomicrobia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
TH3_k127_9183203_2	497964.CfE428DRAFT_0210	1.501e-139	458.0	COG0624@1|root,COG0624@2|Bacteria,46UH8@74201|Verrucomicrobia	74201|Verrucomicrobia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
TH3_k127_9185444_12	56780.SYN_02999	8.409e-21	93.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria,2MRJM@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
TH3_k127_9185444_15	489825.LYNGBM3L_21140	1.569e-17	95.0	COG1216@1|root,COG1216@2|Bacteria,1FZX3@1117|Cyanobacteria,1HA1F@1150|Oscillatoriales	2|Bacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc,Glyco_tranf_2_3,Glycos_transf_2
TH3_k127_9185444_5	357808.RoseRS_2382	3.89e-62	229.0	COG1216@1|root,COG1216@2|Bacteria,2GB2A@200795|Chloroflexi,377SM@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TH3_k127_9185444_6	335541.Swol_2445	4.432e-41	160.0	COG2120@1|root,COG2120@2|Bacteria,1TUFP@1239|Firmicutes,25PKR@186801|Clostridia,42KY4@68298|Syntrophomonadaceae	186801|Clostridia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TH3_k127_9185444_4	251229.Chro_0879	1.244e-70	252.0	COG0438@1|root,COG0438@2|Bacteria,1G0Z5@1117|Cyanobacteria,3VKAC@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TH3_k127_9185444_3	489825.LYNGBM3L_21170	5.811e-136	443.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
TH3_k127_9185444_9	1449976.KALB_4422	2.152e-34	147.0	COG0500@1|root,COG0500@2|Bacteria,2INXQ@201174|Actinobacteria,4EDFK@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
TH3_k127_9185444_0	335543.Sfum_3551	2.9e-178	565.0	COG0438@1|root,COG0438@2|Bacteria,1RAGT@1224|Proteobacteria,42Y8X@68525|delta/epsilon subdivisions,2WU97@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9185444_8	497964.CfE428DRAFT_2920	1.958e-38	152.0	COG0110@1|root,COG0110@2|Bacteria,46T6H@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
TH3_k127_9185444_7	1173026.Glo7428_0927	3.521e-39	154.0	COG0110@1|root,COG0110@2|Bacteria,1G9TY@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Bacterial transferase hexapeptide (three repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
TH3_k127_9185444_2	335543.Sfum_3555	7.66e-138	463.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,43C63@68525|delta/epsilon subdivisions,2WTQK@28221|Deltaproteobacteria,2MSIN@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TH3_k127_9185444_1	489825.LYNGBM3L_21200	5.408e-138	462.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,1H7BU@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TH3_k127_9185444_14	649831.L083_3819	7.867e-19	101.0	COG3979@1|root,COG3979@2|Bacteria,2H72H@201174|Actinobacteria,4DJJD@85008|Micromonosporales	201174|Actinobacteria	S	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9185444_16	313606.M23134_01193	5.16e-13	82.0	COG3469@1|root,COG3979@1|root,COG3469@2|Bacteria,COG3979@2|Bacteria,4PKBR@976|Bacteroidetes,47Y17@768503|Cytophagia	976|Bacteroidetes	G	Carbohydrate binding domain	-	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005576,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016798,GO:0017144,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,CarboxypepD_reg,Glyco_hydro_18
TH3_k127_9185444_10	794903.OPIT5_14550	8.647e-28	121.0	COG2165@1|root,COG2165@2|Bacteria,46Y3B@74201|Verrucomicrobia,3K8VC@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
TH3_k127_9185444_13	864702.OsccyDRAFT_3183	8.138e-20	104.0	COG2931@1|root,COG5434@1|root,COG2931@2|Bacteria,COG5434@2|Bacteria,1G0JG@1117|Cyanobacteria,1HADF@1150|Oscillatoriales	1117|Cyanobacteria	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1349,DUF4347,Pectate_lyase_3
TH3_k127_9185444_11	497964.CfE428DRAFT_5098	1.179e-27	130.0	COG1075@1|root,COG1404@1|root,COG3055@1|root,COG3391@1|root,COG1075@2|Bacteria,COG1404@2|Bacteria,COG3055@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	1.1.3.6,3.2.1.4	ko:K01179,ko:K03333,ko:K12287	ko00500,ko00984,ko01100,ko01120,map00500,map00984,map01100,map01120	-	R01459,R06200,R11307,R11308	RC00146	ko00000,ko00001,ko01000,ko02044	-	GH5,GH9	-	Kelch_1,Laminin_G_3,Malectin
TH3_k127_91941_3	349741.Amuc_0256	5.441e-05	46.0	COG0801@1|root,COG0801@2|Bacteria,46T2Z@74201|Verrucomicrobia,2IUKW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
TH3_k127_91941_0	497964.CfE428DRAFT_0194	0.0	1652.0	COG4284@1|root,COG4284@2|Bacteria,46SCH@74201|Verrucomicrobia	74201|Verrucomicrobia	H	UTP--glucose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGP
TH3_k127_91941_2	497964.CfE428DRAFT_0193	7.035e-111	364.0	COG1210@1|root,COG1210@2|Bacteria,46S5P@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Utp--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TH3_k127_91941_1	497964.CfE428DRAFT_2266	1.815e-199	630.0	COG0477@1|root,COG2814@2|Bacteria,46U08@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
TH3_k127_9198422_0	1303518.CCALI_00634	7.245e-188	601.0	28K2K@1|root,2Z9RX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9198422_1	497964.CfE428DRAFT_4013	9.882e-162	522.0	COG0513@1|root,COG0513@2|Bacteria,46TUA@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
TH3_k127_9207260_5	452637.Oter_4517	4.18e-07	53.0	COG0673@1|root,COG0673@2|Bacteria,46UJR@74201|Verrucomicrobia,3K94Y@414999|Opitutae	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_9207260_2	1396141.BATP01000047_gene3929	2.036e-200	632.0	COG3345@1|root,COG3345@2|Bacteria,46XA8@74201|Verrucomicrobia,2IV69@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
TH3_k127_9207260_1	497964.CfE428DRAFT_1769	7.214e-263	819.0	28MCY@1|root,2ZAQW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9207260_0	497964.CfE428DRAFT_0038	3.329e-283	884.0	28MCY@1|root,2ZAQW@2|Bacteria,46TDW@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9207260_3	1403819.BATR01000027_gene886	8.712e-190	599.0	COG3345@1|root,COG3345@2|Bacteria,46XA8@74201|Verrucomicrobia,2IV69@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
TH3_k127_9207260_4	886293.Sinac_2434	1.218e-41	158.0	COG2730@1|root,COG3250@1|root,COG2730@2|Bacteria,COG3250@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
TH3_k127_9226057_1	867903.ThesuDRAFT_02191	2.93e-111	399.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3WCF4@538999|Clostridiales incertae sedis	186801|Clostridia	L	Helix-hairpin-helix motif	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
TH3_k127_9226057_0	518766.Rmar_0491	2.275e-127	424.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1FJX9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TH3_k127_9242104_3	452637.Oter_0747	1.24e-152	488.0	COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,3K82N@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
TH3_k127_9242104_2	452637.Oter_0746	7.986e-190	598.0	COG0649@1|root,COG0649@2|Bacteria,46SA0@74201|Verrucomicrobia,3K8K5@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
TH3_k127_9242104_9	452637.Oter_0745	1.229e-57	206.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
TH3_k127_9242104_7	452637.Oter_0744	5.931e-90	298.0	COG0377@1|root,COG0377@2|Bacteria,46YVB@74201|Verrucomicrobia,3K85T@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
TH3_k127_9242104_10	452637.Oter_0743	9.92e-52	186.0	COG0838@1|root,COG0838@2|Bacteria,46XVA@74201|Verrucomicrobia,3K8I9@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
TH3_k127_9242104_4	1216966.BAUC01000035_gene3110	2.998e-105	361.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Glutamate synthase	gltD	GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iEC042_1314.EC042_3503,iYL1228.KPN_03625	Fer4_20,Pyr_redox_2
TH3_k127_9242104_1	1267534.KB906754_gene3778	5.727e-198	622.0	COG0649@1|root,COG0649@2|Bacteria,3Y6MU@57723|Acidobacteria,2JKN7@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
TH3_k127_9242104_6	1267534.KB906754_gene3779	1.88e-90	306.0	COG0852@1|root,COG0852@2|Bacteria,3Y72R@57723|Acidobacteria,2JM53@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
TH3_k127_9242104_5	1267534.KB906754_gene3780	3.37e-103	338.0	COG0377@1|root,COG0377@2|Bacteria,3Y74G@57723|Acidobacteria,2JKT1@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
TH3_k127_9242104_12	240015.ACP_2565	2.747e-46	171.0	COG0838@1|root,COG0838@2|Bacteria,3Y8B8@57723|Acidobacteria,2JN67@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
TH3_k127_9242104_0	497964.CfE428DRAFT_2953	1.974e-200	634.0	COG0439@1|root,COG0439@2|Bacteria,46SIE@74201|Verrucomicrobia	74201|Verrucomicrobia	I	acetyl-CoA carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
TH3_k127_9242104_13	478741.JAFS01000001_gene1905	1.516e-37	146.0	COG0511@1|root,COG0511@2|Bacteria,46SXA@74201|Verrucomicrobia,37GQ9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
TH3_k127_9242104_11	1132836.RCCGE510_07356	1.453e-46	172.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2U9BV@28211|Alphaproteobacteria,4BE03@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
TH3_k127_9242104_8	452637.Oter_3865	9.318e-60	213.0	COG0307@1|root,COG0307@2|Bacteria,46SU1@74201|Verrucomicrobia,3K7ZH@414999|Opitutae	414999|Opitutae	H	TIGRFAM riboflavin synthase, alpha subunit	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
TH3_k127_9242104_14	661478.OP10G_0369	1.515e-16	91.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
TH3_k127_9242104_15	886293.Sinac_3736	2.047e-07	62.0	COG2165@1|root,COG2165@2|Bacteria,2J1QS@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_9273242_9	63737.Npun_F5091	9.252e-06	51.0	COG2944@1|root,COG2944@2|Bacteria,1GB8Y@1117|Cyanobacteria	1117|Cyanobacteria	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
TH3_k127_9273242_11	797303.Natpe_3981	0.0003006	46.0	COG2002@1|root,arCOG00812@2157|Archaea,2Y4G4@28890|Euryarchaeota,2404J@183963|Halobacteria	183963|Halobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
TH3_k127_9273242_6	743836.AYNA01000111_gene20	1.621e-09	64.0	COG1487@1|root,COG1487@2|Bacteria,1RJ2J@1224|Proteobacteria,2UA97@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN
TH3_k127_9273242_5	1123367.C666_16960	2.953e-11	72.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales	206389|Rhodocyclales	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
TH3_k127_9273242_10	1260356.D920_00417	0.0002794	47.0	COG1476@1|root,COG1476@2|Bacteria,1TVRT@1239|Firmicutes,4I3Z3@91061|Bacilli,4B5PU@81852|Enterococcaceae	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9273242_4	99598.Cal7507_5777	1.912e-20	112.0	2F43W@1|root,33WVC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9273242_2	340177.Cag_0614	7.569e-59	239.0	COG1357@1|root,COG2931@1|root,COG3210@1|root,COG4625@1|root,COG1357@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	rhgB	-	4.2.2.23	ko:K07004,ko:K18195	-	-	-	-	ko00000,ko01000	-	PL4	-	CBM-like,RhgB_N,fn3_3
TH3_k127_9273242_0	583355.Caka_2045	1.317e-263	919.0	COG0771@1|root,COG2911@1|root,COG2931@1|root,COG0771@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	murD	-	3.4.21.10,6.3.2.13,6.3.2.9	ko:K01317,ko:K01925,ko:K01928,ko:K01932	ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100	-	R02783,R02788	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01002,ko01011,ko04131	-	-	-	DUF1727,Mur_ligase_C,Mur_ligase_M
TH3_k127_9273242_1	272134.KB731324_gene6505	3.064e-68	271.0	COG1404@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1G7AR@1117|Cyanobacteria,1HBKR@1150|Oscillatoriales	1117|Cyanobacteria	OQ	PFAM FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TH3_k127_9273242_8	926560.KE387027_gene1014	3.955e-07	68.0	COG2247@1|root,COG2247@2|Bacteria,1WNI9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9273242_7	926550.CLDAP_39920	2.288e-07	68.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	DUF1929,F5_F8_type_C,Glyco_hyd_65N_2,Glyco_hydro_18,He_PIG,PA14,RCC1,SLH
TH3_k127_9273242_3	696747.NIES39_O02270	6.184e-28	137.0	COG2931@1|root,COG4675@1|root,COG2931@2|Bacteria,COG4675@2|Bacteria,1GFPS@1117|Cyanobacteria,1HHVN@1150|Oscillatoriales	1117|Cyanobacteria	Q	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TH3_k127_927728_4	1192868.CAIU01000040_gene4440	1.488e-08	56.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,43HGG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TH3_k127_927728_1	1121101.HMPREF1532_01876	1.033e-122	417.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,2FVA6@200643|Bacteroidia,4AT0B@815|Bacteroidaceae	976|Bacteroidetes	G	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
TH3_k127_927728_3	880073.Calab_0674	4.083e-12	79.0	COG1520@1|root,COG2911@1|root,COG3420@1|root,COG1520@2|Bacteria,COG2911@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729,ko:K17713	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000,ko02000	1.B.33.1	-	-	Beta_helix,Big_4,CHU_C,CarboxypepD_reg,DUF5050,HYR,Peptidase_S8,SprB
TH3_k127_927728_5	497964.CfE428DRAFT_4678	5.101e-08	66.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,Big_2,CarboxypepD_reg,He_PIG,LysM,PSII_BNR,SLH,TIG,fn3
TH3_k127_927728_0	452637.Oter_4539	1.804e-145	468.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
TH3_k127_927728_2	621372.ACIH01000072_gene1944	1.748e-59	223.0	COG2942@1|root,COG2942@2|Bacteria,1TQMG@1239|Firmicutes,4HE7U@91061|Bacilli,26T2B@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	rnbP	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
TH3_k127_9323237_4	240016.ABIZ01000001_gene5569	9.793e-17	93.0	COG1053@1|root,COG1053@2|Bacteria,46S51@74201|Verrucomicrobia,2IVH2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
TH3_k127_9323237_1	1123277.KB893206_gene3466	5.717e-128	420.0	COG1621@1|root,COG1621@2|Bacteria,4NJ8X@976|Bacteroidetes,47N6D@768503|Cytophagia	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
TH3_k127_9323237_3	999419.HMPREF1077_01244	3.941e-74	260.0	COG2273@1|root,COG2273@2|Bacteria,4P31M@976|Bacteroidetes,2G2G9@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
TH3_k127_9323237_0	497964.CfE428DRAFT_0023	5.074e-149	478.0	2EY4V@1|root,33RDN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9323237_2	349521.HCH_01563	4.401e-81	275.0	COG0657@1|root,COG0657@2|Bacteria,1R4AU@1224|Proteobacteria,1RQMN@1236|Gammaproteobacteria,1XR8Q@135619|Oceanospirillales	135619|Oceanospirillales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
TH3_k127_9351797_9	572477.Alvin_2130	1.301e-16	80.0	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,1S0Y4@1236|Gammaproteobacteria,1WX3Z@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
TH3_k127_9351797_12	1207075.PputUW4_04220	0.0001286	52.0	COG3708@1|root,COG3708@2|Bacteria,1NBPE@1224|Proteobacteria,1SFP2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like
TH3_k127_9351797_0	525904.Tter_0327	5.507e-282	884.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
TH3_k127_9351797_6	1396141.BATP01000034_gene4147	7.819e-37	149.0	COG3189@1|root,COG3189@2|Bacteria,46VV6@74201|Verrucomicrobia,2IWA9@203494|Verrucomicrobiae	2|Bacteria	S	Protein of unknown function, DUF488	yeaO	-	-	-	-	-	-	-	-	-	-	-	DUF488
TH3_k127_9351797_5	290397.Adeh_2684	3.757e-41	158.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2WPDF@28221|Deltaproteobacteria,2YVGY@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
TH3_k127_9351797_8	404380.Gbem_1922	1.448e-23	119.0	COG1361@1|root,COG3055@1|root,COG3420@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,COG3420@2|Bacteria,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,43VN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
TH3_k127_9351797_7	251221.35213566	8.598e-30	139.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9351797_1	382464.ABSI01000013_gene1839	1.727e-97	358.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,46UMW@74201|Verrucomicrobia,2IUFG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,Peptidase_S8
TH3_k127_9351797_11	1396141.BATP01000058_gene1991	4.187e-06	60.0	COG1572@1|root,COG2010@1|root,COG2133@1|root,COG1572@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
TH3_k127_9351797_3	575540.Isop_0876	5.901e-48	194.0	COG2931@1|root,COG2931@2|Bacteria,2J1K0@203682|Planctomycetes	203682|Planctomycetes	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9351797_4	497964.CfE428DRAFT_4746	2.946e-41	168.0	COG0258@1|root,COG0258@2|Bacteria,46SWB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	5'-3' exonuclease	exo	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N
TH3_k127_9351797_2	1396418.BATQ01000167_gene1757	1.801e-65	239.0	COG0457@1|root,COG1450@1|root,COG0457@2|Bacteria,COG1450@2|Bacteria,46TXY@74201|Verrucomicrobia,2ITGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Bacterial type II and III secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Secretin,TPR_16,TPR_8
TH3_k127_9356687_4	883.DvMF_1002	0.0002543	44.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria,2MA1I@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
TH3_k127_9356687_0	497964.CfE428DRAFT_3334	1.468e-115	385.0	COG0156@1|root,COG0156@2|Bacteria,46TTU@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TH3_k127_9356687_1	497964.CfE428DRAFT_2596	1.799e-89	310.0	COG0402@1|root,COG0402@2|Bacteria,46TB5@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Amidohydrolase family	ssnA	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TH3_k127_9356687_3	481448.Minf_1981	3.938e-09	64.0	COG1544@1|root,COG1544@2|Bacteria,46WSI@74201|Verrucomicrobia,37HA3@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
TH3_k127_9356687_2	497964.CfE428DRAFT_5497	1.356e-36	151.0	COG1192@1|root,COG1192@2|Bacteria,46SKQ@74201|Verrucomicrobia	74201|Verrucomicrobia	D	PFAM Cobyrinic acid ac-diamide synthase	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
TH3_k127_9371750_0	1122176.KB903598_gene4712	2.797e-117	400.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CW_binding_1,HYR
TH3_k127_9371750_2	497964.CfE428DRAFT_4990	5.919e-69	255.0	COG3071@1|root,COG3071@2|Bacteria,46VFP@74201|Verrucomicrobia	74201|Verrucomicrobia	H	HemY protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9371750_1	1442599.JAAN01000005_gene1008	5.249e-101	342.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1X46C@135614|Xanthomonadales	135614|Xanthomonadales	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TH3_k127_9371750_3	382464.ABSI01000012_gene1959	1.724e-58	209.0	COG1086@1|root,COG1086@2|Bacteria,46UPP@74201|Verrucomicrobia,2IVCB@203494|Verrucomicrobiae	2|Bacteria	GM	Polysaccharide biosynthesis protein	capD	GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192	4.2.1.115,4.2.1.135,4.2.1.46	ko:K01710,ko:K15894,ko:K15912,ko:K19421	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R06513,R09697	RC00402,RC02609	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding_3,Polysacc_synt_2
TH3_k127_94088_30	1123242.JH636434_gene4702	1.003e-09	68.0	2B9HV@1|root,322W0@2|Bacteria,2IZR4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_94088_31	1142394.PSMK_11740	3.456e-08	64.0	COG2165@1|root,COG2165@2|Bacteria,2IXWH@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_94088_4	670307.HYPDE_33213	5.138e-154	509.0	COG3011@1|root,COG3011@2|Bacteria,1N0MB@1224|Proteobacteria	1224|Proteobacteria	S	Lipase maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,LMF1
TH3_k127_94088_24	1173023.KE650771_gene1836	4.033e-24	113.0	COG1262@1|root,COG2944@1|root,COG1262@2|Bacteria,COG2944@2|Bacteria,1G0ZT@1117|Cyanobacteria	1117|Cyanobacteria	D	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,TIR_2
TH3_k127_94088_23	706587.Desti_1336	9.709e-25	110.0	COG2771@1|root,COG2771@2|Bacteria,1NAK1@1224|Proteobacteria,42VEJ@68525|delta/epsilon subdivisions,2WS0Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Protein of unknown function (DUF4019)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4019
TH3_k127_94088_1	452637.Oter_3479	0.0	1162.0	COG0129@1|root,COG0129@2|Bacteria,46UGZ@74201|Verrucomicrobia,3K7Q8@414999|Opitutae	414999|Opitutae	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
TH3_k127_94088_2	1123508.JH636448_gene7659	1.193e-199	629.0	COG2730@1|root,COG2730@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
TH3_k127_94088_11	240016.ABIZ01000001_gene2238	9.771e-102	344.0	COG1250@1|root,COG1250@2|Bacteria,46TNQ@74201|Verrucomicrobia,2IWBJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	3-hydroxyacyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_94088_8	344747.PM8797T_24141	2.182e-130	427.0	COG1520@1|root,COG1520@2|Bacteria,2IYK2@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
TH3_k127_94088_21	1267535.KB906767_gene4834	8.445e-34	146.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,Glyco_hydro_14,Glyco_hydro_42,Glyco_hydro_42M
TH3_k127_94088_6	344747.PM8797T_25701	1.072e-153	496.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
TH3_k127_94088_10	543728.Vapar_4636	9.723e-107	355.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,2VM9V@28216|Betaproteobacteria,4ADDA@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Periplasmic binding protein LacI transcriptional regulator	rbsB2	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
TH3_k127_94088_12	1123487.KB892834_gene3009	1.344e-98	331.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2WH7G@28216|Betaproteobacteria,2KZQT@206389|Rhodocyclales	28216|Betaproteobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
TH3_k127_94088_13	1123248.KB893329_gene4465	2.965e-93	317.0	COG0524@1|root,COG0524@2|Bacteria,4NENQ@976|Bacteroidetes,1IUX3@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
TH3_k127_94088_28	251221.35210810	2.29e-12	68.0	COG5295@1|root,COG5295@2|Bacteria,1GB93@1117|Cyanobacteria	1117|Cyanobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_94088_29	324602.Caur_0300	4.492e-11	69.0	290K2@1|root,2ZN8K@2|Bacteria,2G9HM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_94088_3	1123242.JH636434_gene5419	9.799e-158	507.0	COG3356@1|root,COG3356@2|Bacteria,2IXX5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
TH3_k127_94088_27	278957.ABEA03000074_gene2977	2.289e-13	81.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_94088_19	234267.Acid_3103	6.766e-45	166.0	COG4948@1|root,COG4948@2|Bacteria,3Y46A@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
TH3_k127_94088_7	641524.ADICYQ_2925	3.302e-143	462.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,47ME7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_94088_26	247490.KSU1_D0417	2.151e-13	71.0	COG1052@1|root,COG1052@2|Bacteria,2IWTC@203682|Planctomycetes	203682|Planctomycetes	CH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TH3_k127_94088_5	471854.Dfer_1899	6.89e-154	496.0	COG4409@1|root,COG4409@2|Bacteria,4NKEW@976|Bacteroidetes,47U77@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TH3_k127_94088_18	452637.Oter_3648	1.039e-49	190.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3,SirB
TH3_k127_94088_15	278957.ABEA03000104_gene310	3.228e-81	275.0	COG0560@1|root,COG0560@2|Bacteria,46X2A@74201|Verrucomicrobia,3K7WQ@414999|Opitutae	414999|Opitutae	E	TIGRFAM phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	-	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase
TH3_k127_94088_25	1385935.N836_13145	4.262e-15	92.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_94088_0	1396141.BATP01000016_gene2780	0.0	1552.0	COG1075@1|root,COG4099@1|root,COG4625@1|root,COG1075@2|Bacteria,COG4099@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	3.5.4.40	ko:K18286,ko:K20276	ko00130,ko01110,ko02024,map00130,map01110,map02024	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_8,Big_5,SLH,SWM_repeat
TH3_k127_94088_14	243231.GSU0006	1.599e-82	291.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,43TUN@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
TH3_k127_94088_20	1123070.KB899247_gene1454	1.426e-43	167.0	COG0344@1|root,COG0344@2|Bacteria,46VTA@74201|Verrucomicrobia,2IUDC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Glycerol-3-phosphate acyltransferase	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
TH3_k127_94088_9	497964.CfE428DRAFT_0881	1.925e-107	359.0	COG0673@1|root,COG0673@2|Bacteria,46SAE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	mviM	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_94088_17	481448.Minf_1859	4.739e-70	257.0	COG0763@1|root,COG0763@2|Bacteria,46SSG@74201|Verrucomicrobia,37GGI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
TH3_k127_94088_22	497964.CfE428DRAFT_6314	9.15e-27	113.0	2E63P@1|root,330SQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_94088_16	497964.CfE428DRAFT_5455	3.523e-71	246.0	COG2344@1|root,COG2344@2|Bacteria	2|Bacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
TH3_k127_944060_2	936154.STP_1609	0.0007783	46.0	COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,1VDKY@1239|Firmicutes,4IS6B@91061|Bacilli	91061|Bacilli	K	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_S24
TH3_k127_944060_0	1379698.RBG1_1C00001G1377	1.082e-34	152.0	COG4409@1|root,COG4409@2|Bacteria,2NRD7@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
TH3_k127_944060_1	794903.OPIT5_05990	3.276e-06	55.0	COG2165@1|root,COG2165@2|Bacteria,46YG4@74201|Verrucomicrobia,3K9HT@414999|Opitutae	414999|Opitutae	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_9458167_7	1123278.KB893545_gene4805	1.222e-80	292.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,47K8Y@768503|Cytophagia	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
TH3_k127_9458167_5	429009.Adeg_0221	4.288e-117	383.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC3@186801|Clostridia,42F8X@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TH3_k127_9458167_12	497964.CfE428DRAFT_3441	9.509e-52	189.0	COG3880@1|root,COG3880@2|Bacteria,46SXX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM UvrB UvrC protein	mcsA	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
TH3_k127_9458167_3	497964.CfE428DRAFT_3440	5.035e-130	428.0	COG3869@1|root,COG3869@2|Bacteria,46S55@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Protein-arginine kinase	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
TH3_k127_9458167_0	1396141.BATP01000059_gene2466	0.0	1015.0	COG0542@1|root,COG0542@2|Bacteria,46SD6@74201|Verrucomicrobia,2ITPB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
TH3_k127_9458167_9	880073.Calab_1235	2.239e-61	225.0	COG0035@1|root,COG0035@2|Bacteria,2NP5M@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11010	UPRTase
TH3_k127_9458167_10	497964.CfE428DRAFT_3693	2.295e-61	226.0	COG0616@1|root,COG0616@2|Bacteria,46SQ5@74201|Verrucomicrobia	74201|Verrucomicrobia	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
TH3_k127_9458167_16	696281.Desru_0074	1.038e-18	93.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,261Y7@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
TH3_k127_9458167_18	661478.OP10G_4100	0.0002177	44.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,VCBS
TH3_k127_9458167_8	497964.CfE428DRAFT_0202	2.259e-69	242.0	COG0299@1|root,COG0299@2|Bacteria,46SS6@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
TH3_k127_9458167_4	497964.CfE428DRAFT_5666	3.961e-118	389.0	COG0040@1|root,COG0040@2|Bacteria,46SHK@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Histidine biosynthesis protein HisG domain	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
TH3_k127_9458167_13	497964.CfE428DRAFT_5668	2.825e-46	188.0	COG0457@1|root,COG0457@2|Bacteria,46V4J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_8
TH3_k127_9458167_17	309801.trd_A0913	2.689e-17	87.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi,27YIV@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
TH3_k127_9458167_1	497964.CfE428DRAFT_0348	1.093e-236	759.0	COG0612@1|root,COG0612@2|Bacteria,46S9I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TH3_k127_9458167_14	452637.Oter_2367	2.665e-36	145.0	2E5IJ@1|root,3309Y@2|Bacteria,46SYV@74201|Verrucomicrobia,3K87A@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9458167_11	452637.Oter_1864	9.214e-54	198.0	COG3327@1|root,COG3327@2|Bacteria,46W9G@74201|Verrucomicrobia	74201|Verrucomicrobia	K	negative regulation of DNA-templated transcription, initiation	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX_C
TH3_k127_9458167_6	452637.Oter_1808	9.2e-84	290.0	COG2378@1|root,COG2378@2|Bacteria,46VG3@74201|Verrucomicrobia,3K846@414999|Opitutae	414999|Opitutae	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	WYL
TH3_k127_9458167_2	497964.CfE428DRAFT_4940	1.647e-137	442.0	COG1099@1|root,COG1099@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
TH3_k127_9458167_15	497964.CfE428DRAFT_4941	2.012e-22	101.0	2E5PI@1|root,330E7@2|Bacteria,46W49@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9460421_20	595460.RRSWK_06189	3.144e-10	63.0	COG1894@1|root,COG1894@2|Bacteria,2IXJ8@203682|Planctomycetes	203682|Planctomycetes	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
TH3_k127_9460421_5	497964.CfE428DRAFT_5712	5.719e-119	406.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	2|Bacteria	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_9460421_8	1168034.FH5T_01555	6.516e-109	369.0	COG0348@1|root,COG0348@2|Bacteria,4NPVD@976|Bacteroidetes,2FTEY@200643|Bacteroidia	976|Bacteroidetes	C	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
TH3_k127_9460421_13	1168034.FH5T_01560	5.044e-69	240.0	2DVMZ@1|root,33WFQ@2|Bacteria,4P3VR@976|Bacteroidetes,2FXVM@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	-
TH3_k127_9460421_14	595460.RRSWK_06184	7.809e-48	184.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
TH3_k127_9460421_6	595460.RRSWK_06183	3.984e-114	384.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TH3_k127_9460421_10	452637.Oter_3509	3.961e-89	310.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_9460421_15	1123242.JH636434_gene5340	1.359e-37	162.0	COG1413@1|root,COG1413@2|Bacteria,2IZE1@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
TH3_k127_9460421_1	272134.KB731324_gene3214	3.588e-251	797.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1G1Q1@1117|Cyanobacteria,1H8JB@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3471,PD40,Peptidase_S9,Peptidase_S9_N
TH3_k127_9460421_22	671143.DAMO_0355	4.57e-07	55.0	COG4096@1|root,COG4096@2|Bacteria	2|Bacteria	L	type I site-specific deoxyribonuclease activity	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
TH3_k127_9460421_7	1116472.MGMO_115c00240	7.175e-110	372.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
TH3_k127_9460421_19	1121924.ATWH01000005_gene2605	5.532e-13	82.0	COG1874@1|root,COG1874@2|Bacteria,2H2YV@201174|Actinobacteria,4FQYV@85023|Microbacteriaceae	201174|Actinobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9460421_16	765952.PUV_26370	1.558e-28	118.0	2E3V1@1|root,32YSA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9460421_21	1217705.F900_00640	1.197e-08	58.0	2E5S4@1|root,330GM@2|Bacteria,1NAY4@1224|Proteobacteria,1SEIX@1236|Gammaproteobacteria,3NPRS@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9460421_3	1232410.KI421412_gene312	9.983e-164	541.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,43RY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	UvrD-like helicase C-terminal domain	rep	-	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
TH3_k127_9460421_0	1396141.BATP01000034_gene4198	3.115e-291	966.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
TH3_k127_9460421_12	583355.Caka_1736	3.522e-70	274.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
TH3_k127_9460421_18	96561.Dole_1704	3.17e-22	114.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9460421_9	518766.Rmar_0474	9.18e-106	354.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
TH3_k127_9460421_4	583355.Caka_0968	3.707e-140	467.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,46UC1@74201|Verrucomicrobia,3K9FB@414999|Opitutae	414999|Opitutae	C	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9460421_17	1353531.AZNX01000005_gene3441	6.442e-23	103.0	COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,2TTJ7@28211|Alphaproteobacteria,4BC0Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
TH3_k127_9460421_2	404589.Anae109_3197	6.091e-171	550.0	COG2855@1|root,COG2855@2|Bacteria,1MVPE@1224|Proteobacteria,42NT6@68525|delta/epsilon subdivisions,2WJ9R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	family UPF0324	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
TH3_k127_9460421_11	382464.ABSI01000009_gene3915	8.008e-73	256.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_950256_7	411902.CLOBOL_03557	5.396e-24	106.0	COG2721@1|root,COG2721@2|Bacteria,1TUD7@1239|Firmicutes,24R3M@186801|Clostridia,221BF@1506553|Lachnoclostridium	186801|Clostridia	G	SAF domain	-	-	-	-	-	-	-	-	-	-	-	-	SAF
TH3_k127_950256_1	1123269.NX02_17320	1.186e-191	606.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2TTDT@28211|Alphaproteobacteria,2K15R@204457|Sphingomonadales	204457|Sphingomonadales	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C
TH3_k127_950256_3	1123242.JH636434_gene4153	1.529e-152	492.0	COG4409@1|root,COG4409@2|Bacteria,2J53Z@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TH3_k127_950256_4	1403819.BATR01000135_gene4812	5.242e-115	380.0	COG0329@1|root,COG0329@2|Bacteria,46UU4@74201|Verrucomicrobia	74201|Verrucomicrobia	EM	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
TH3_k127_950256_8	1142394.PSMK_06110	6.072e-13	79.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_950256_5	583355.Caka_0956	4.969e-92	319.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
TH3_k127_950256_2	380358.XALC_0037	7.026e-158	511.0	COG2271@1|root,COG2271@2|Bacteria,1MV04@1224|Proteobacteria,1RP70@1236|Gammaproteobacteria,1X56Y@135614|Xanthomonadales	135614|Xanthomonadales	G	Major facilitator superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
TH3_k127_950256_6	42256.RradSPS_2706	1.501e-63	233.0	COG4671@1|root,COG4671@2|Bacteria,2IAST@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
TH3_k127_950256_0	28072.Nos7524_1737	3.232e-209	668.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,1HM11@1161|Nostocales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TH3_k127_950256_9	380394.Lferr_0767	7.562e-13	72.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RYBJ@1236|Gammaproteobacteria,2NDM4@225057|Acidithiobacillales	225057|Acidithiobacillales	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
TH3_k127_9572441_9	497964.CfE428DRAFT_6595	9.168e-51	182.0	COG0480@1|root,COG0480@2|Bacteria	2|Bacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
TH3_k127_9572441_18	1125700.HMPREF9195_01844	2.118e-06	58.0	2AIAW@1|root,318RT@2|Bacteria,2J6NU@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9572441_17	742159.HMPREF0004_3321	5.768e-09	64.0	COG0745@1|root,COG2199@1|root,COG5002@1|root,COG5278@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,1R7HC@1224|Proteobacteria,2W0FN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,Response_reg
TH3_k127_9572441_12	497964.CfE428DRAFT_3383	3.523e-40	156.0	COG0262@1|root,COG0262@2|Bacteria,46T19@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Dihydrofolate reductase	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
TH3_k127_9572441_4	1379698.RBG1_1C00001G0607	1.748e-91	338.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
TH3_k127_9572441_10	1082933.MEA186_30762	1.767e-44	187.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43NVJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
TH3_k127_9572441_13	243090.RB9985	5.352e-38	149.0	28JE3@1|root,2Z98B@2|Bacteria,2J0PD@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9572441_20	1047013.AQSP01000089_gene1181	1.286e-05	48.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cyaJ	-	4.6.1.1	ko:K01768,ko:K02483	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_19,TPR_2,TPR_8
TH3_k127_9572441_8	760192.Halhy_1187	2.441e-62	223.0	COG0363@1|root,COG0363@2|Bacteria,4NPBJ@976|Bacteroidetes,1IYJE@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02080,ko:K02564	ko00052,ko00520,ko01100,map00052,map00520,map01100	-	R00765,R08365	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
TH3_k127_9572441_6	525904.Tter_2139	7.8e-67	239.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TH3_k127_9572441_1	525904.Tter_2133	7.071e-129	422.0	COG0646@1|root,COG0646@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13,2.1.1.5	ko:K00544,ko:K00548	ko00260,ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00260,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R02821,R09365	RC00035,RC00113,RC00496,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
TH3_k127_9572441_14	1163409.UUA_06087	3.802e-21	104.0	COG0697@1|root,COG0697@2|Bacteria,1PXBY@1224|Proteobacteria,1TCXJ@1236|Gammaproteobacteria,1X9UW@135614|Xanthomonadales	135614|Xanthomonadales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TH3_k127_9572441_16	1457250.BBMO01000003_gene3175	1.639e-11	72.0	COG0456@1|root,arCOG00833@2157|Archaea,2Y0NY@28890|Euryarchaeota,23Y3K@183963|Halobacteria	183963|Halobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TH3_k127_9572441_11	66874.JOFS01000006_gene4504	6.977e-44	186.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,WD40
TH3_k127_9572441_5	502025.Hoch_1100	2.159e-80	305.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42PPB@68525|delta/epsilon subdivisions,2X5YN@28221|Deltaproteobacteria,2YUEJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12
TH3_k127_9572441_0	1047013.AQSP01000089_gene1181	5.102e-140	470.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cyaJ	-	4.6.1.1	ko:K01768,ko:K02483	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_19,TPR_2,TPR_8
TH3_k127_9572441_2	1210884.HG799469_gene14163	1.673e-121	406.0	COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
TH3_k127_9572441_15	1303518.CCALI_01258	1.658e-13	79.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TH3_k127_9572441_3	1396141.BATP01000056_gene3118	1.197e-117	400.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia,2IWN1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
TH3_k127_9572441_7	382464.ABSI01000010_gene3853	1.677e-62	226.0	COG4912@1|root,COG4912@2|Bacteria	2|Bacteria	L	Dna alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
TH3_k127_9572441_22	452637.Oter_1848	0.000958	45.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TH3_k127_9572441_21	452637.Oter_1848	3.002e-05	48.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TH3_k127_9575338_1	768706.Desor_4071	1.015e-115	380.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,260EI@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TH3_k127_9575338_3	1304874.JAFY01000002_gene597	1.341e-34	141.0	COG0778@1|root,COG0778@2|Bacteria,3TB6G@508458|Synergistetes	508458|Synergistetes	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
TH3_k127_9575338_2	226186.BT_2529	1.395e-82	290.0	COG0613@1|root,COG0613@2|Bacteria,4NHZ5@976|Bacteroidetes,2FQW5@200643|Bacteroidia,4AN9D@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	DUF5001
TH3_k127_9575338_0	661478.OP10G_0514	4.616e-232	749.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,F5_F8_type_C,Lactonase,Phosphoesterase
TH3_k127_9575338_4	1192034.CAP_5127	3.658e-33	146.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,4341P@68525|delta/epsilon subdivisions,2X4PD@28221|Deltaproteobacteria,2YZCK@29|Myxococcales	28221|Deltaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Lectin_C
TH3_k127_9575338_5	880072.Desac_0910	1.798e-31	130.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria	1224|Proteobacteria	V	type I restriction-modification system	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HTH_31,HsdM_N,N6_Mtase
TH3_k127_9674707_2	1123393.KB891328_gene694	2.023e-85	291.0	COG2378@1|root,COG2378@2|Bacteria,1P2ZE@1224|Proteobacteria,2VMDI@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Helix-turn-helix type 11	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
TH3_k127_9674707_7	228410.NE0834	1.109e-21	98.0	COG1203@1|root,COG1203@2|Bacteria,1MX7A@1224|Proteobacteria,2VJQY@28216|Betaproteobacteria,3740J@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C
TH3_k127_9674707_4	768710.DesyoDRAFT_3721	5.266e-77	284.0	2ED7F@1|root,33741@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9674707_1	457415.HMPREF1006_00598	2.234e-115	378.0	COG3649@1|root,COG3649@2|Bacteria	2|Bacteria	L	CRISPR-associated protein Cas7	cas7	-	-	ko:K19115	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas7
TH3_k127_9674707_0	768710.DesyoDRAFT_3719	1.747e-182	595.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,260BW@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM CRISPR-associated helicase Cas3	-	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C,ResIII
TH3_k127_9674707_5	1123393.KB891328_gene689	2.954e-74	254.0	COG1468@1|root,COG1468@2|Bacteria,1MX2S@1224|Proteobacteria,2VR7Q@28216|Betaproteobacteria,1KRZH@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Domain of unknown function DUF83	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4
TH3_k127_9674707_6	42256.RradSPS_3110	1.138e-36	141.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9674707_8	1183438.GKIL_3127	9.148e-19	87.0	2E6Q0@1|root,331A9@2|Bacteria,1G9WU@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4926)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4926
TH3_k127_9675921_20	211586.SO_0853	0.0003834	51.0	COG4970@1|root,COG4970@2|Bacteria,1PC9R@1224|Proteobacteria,1SX5Y@1236|Gammaproteobacteria,2QCSM@267890|Shewanellaceae	1236|Gammaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
TH3_k127_9675921_19	1403819.BATR01000181_gene6136	6.991e-05	54.0	COG4968@1|root,COG4968@2|Bacteria,46WJ1@74201|Verrucomicrobia,2IUWN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
TH3_k127_9675921_18	1210884.HG799475_gene15301	3.288e-06	57.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_9675921_16	497964.CfE428DRAFT_6148	2.139e-27	113.0	2DTD6@1|root,33JTS@2|Bacteria,46WA4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CopG antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
TH3_k127_9675921_17	1396418.BATQ01000166_gene1838	2.285e-23	102.0	2FCWX@1|root,344ZT@2|Bacteria,46WDE@74201|Verrucomicrobia,2IUVW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
TH3_k127_9675921_6	497964.CfE428DRAFT_1451	4.312e-136	446.0	COG1459@1|root,COG1459@2|Bacteria,46S8P@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	type II secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
TH3_k127_9675921_1	497964.CfE428DRAFT_1455	5.767e-217	687.0	COG2804@1|root,COG2804@2|Bacteria,46UFR@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
TH3_k127_9675921_4	452637.Oter_3084	7.753e-142	459.0	COG2805@1|root,COG2805@2|Bacteria,46S5Q@74201|Verrucomicrobia,3K79X@414999|Opitutae	414999|Opitutae	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
TH3_k127_9675921_2	497964.CfE428DRAFT_1457	1.677e-198	633.0	COG2804@1|root,COG2804@2|Bacteria,46SDR@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	General secretory system II protein E domain protein	pulE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
TH3_k127_9675921_3	344747.PM8797T_29708	5.036e-180	573.0	COG4409@1|root,COG4409@2|Bacteria,2IYPT@203682|Planctomycetes	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Big_2,DUF4091,FIVAR,Laminin_G_3
TH3_k127_9675921_10	481448.Minf_0287	3.903e-112	372.0	COG0191@1|root,COG0191@2|Bacteria,46TAJ@74201|Verrucomicrobia,37GA3@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
TH3_k127_9675921_12	649349.Lbys_0013	1.356e-106	354.0	COG3718@1|root,COG3718@2|Bacteria,4NKW4@976|Bacteroidetes,47TKD@768503|Cytophagia	976|Bacteroidetes	G	KduI/IolB family	-	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
TH3_k127_9675921_5	485913.Krac_4319	2.724e-141	456.0	COG0524@1|root,COG0524@2|Bacteria,2G5XM@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
TH3_k127_9675921_0	485913.Krac_4320	7.396e-256	810.0	COG3962@1|root,COG3962@2|Bacteria,2G68S@200795|Chloroflexi	200795|Chloroflexi	E	Thiamine pyrophosphate enzyme, central domain	-	-	3.7.1.22	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08603	RC02331	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TH3_k127_9675921_9	926550.CLDAP_26140	1.021e-116	386.0	COG1082@1|root,COG1082@2|Bacteria,2G613@200795|Chloroflexi	200795|Chloroflexi	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
TH3_k127_9675921_8	1499967.BAYZ01000182_gene4442	1.782e-118	389.0	COG0673@1|root,COG0673@2|Bacteria,2NQJN@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	iolG	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_9675921_7	1268240.ATFI01000008_gene2321	4.695e-132	435.0	COG2271@1|root,COG2271@2|Bacteria,4NH5M@976|Bacteroidetes,2FNV1@200643|Bacteroidia,4AMZP@815|Bacteroidaceae	976|Bacteroidetes	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
TH3_k127_9675921_13	521045.Kole_0981	4.86e-79	276.0	COG0524@1|root,COG0524@2|Bacteria,2GDS1@200918|Thermotogae	200918|Thermotogae	H	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
TH3_k127_9675921_14	861299.J421_0058	5.964e-67	238.0	COG1611@1|root,COG1611@2|Bacteria,1ZT7E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
TH3_k127_9675921_11	1122947.FR7_2048	8.609e-107	363.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4H6Y8@909932|Negativicutes	909932|Negativicutes	EH	Anthranilate synthase component I, N terminal region	-	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
TH3_k127_9675921_15	247490.KSU1_C0572	3.963e-45	175.0	COG0115@1|root,COG0115@2|Bacteria,2J20K@203682|Planctomycetes	203682|Planctomycetes	EH	Amino-transferase class IV	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_4
TH3_k127_9767161_3	1122217.KB899606_gene399	7.996e-11	66.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,4H40K@909932|Negativicutes	909932|Negativicutes	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
TH3_k127_9767161_0	497964.CfE428DRAFT_6644	9.251e-241	762.0	COG1657@1|root,COG1657@2|Bacteria,46TK5@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene-hopene cyclase N-terminal domain	sqhC	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
TH3_k127_9767161_1	112098.XP_008616287.1	6.442e-92	310.0	COG0253@1|root,2QQKJ@2759|Eukaryota	2759|Eukaryota	E	diaminopimelate epimerase activity	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
TH3_k127_9767161_2	1123070.KB899251_gene722	2.839e-59	211.0	COG0329@1|root,COG0329@2|Bacteria,46SDY@74201|Verrucomicrobia,2ITUK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EM	Dihydrodipicolinate synthetase family	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
TH3_k127_9858143_2	204669.Acid345_3016	1.371e-33	132.0	COG0531@1|root,COG0531@2|Bacteria,3Y3GY@57723|Acidobacteria,2JHIT@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
TH3_k127_9858143_1	880072.Desac_2413	1.345e-111	374.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2WKT8@28221|Deltaproteobacteria,2MR4U@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4921)	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
TH3_k127_9858143_0	240016.ABIZ01000001_gene1742	5.609e-113	377.0	COG1861@1|root,COG1861@2|Bacteria,46UVT@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
TH3_k127_9858539_5	575540.Isop_0126	6.514e-14	83.0	COG2165@1|root,COG2165@2|Bacteria,2J1UJ@203682|Planctomycetes	2|Bacteria	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
TH3_k127_9858539_2	344747.PM8797T_26405	8.482e-105	357.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TH3_k127_9858539_4	1303518.CCALI_00602	1.196e-14	85.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
TH3_k127_9858539_3	382464.ABSI01000013_gene1723	1.546e-98	353.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Redoxin,Thioredoxin_8,UnbV_ASPIC,VCBS
TH3_k127_9858539_0	497964.CfE428DRAFT_5300	1.767e-159	513.0	COG0673@1|root,COG0673@2|Bacteria,46S8U@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TH3_k127_9858539_1	1210884.HG799468_gene13605	3.06e-151	497.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Polysacc_deac_1,Polysacc_deac_3
TH3_k127_9886968_1	1235803.C825_03120	1.939e-193	618.0	COG1331@1|root,COG1331@2|Bacteria,4NIS8@976|Bacteroidetes,2FRC4@200643|Bacteroidia	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TH3_k127_9886968_0	509635.N824_01000	1.009e-229	741.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,DUF5054,Glyco_hydro_38,Glyco_hydro_38C
## 5479 queries scanned
## Total time (seconds): 108.31728434562683
## Rate: 50.58 q/s