## Thu Oct 17 14:55:35 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/TLS2_bin.49.fa -m mmseqs --itype genome -o TLS2_bin.49 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/TLS2_bin.49 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
TLS2_k127_1005851_0	1122603.ATVI01000005_gene2916	3.85e-293	931.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X5NX@135614|Xanthomonadales	135614|Xanthomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS2_k127_1005851_1	1158292.JPOE01000002_gene1844	3.094e-12	68.0	COG3961@1|root,COG3961@2|Bacteria,1MW2F@1224|Proteobacteria,2VIQN@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the TPP enzyme family	ipdC	-	4.1.1.74	ko:K04103	ko00380,ko01100,map00380,map01100	-	R01974	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TLS2_k127_1010654_2	543728.Vapar_0245	4.939e-21	96.0	COG0179@1|root,COG0179@2|Bacteria,1R51B@1224|Proteobacteria,2VSKH@28216|Betaproteobacteria,4ADM6@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	4.1.1.68	ko:K05921	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04134,R04380	RC01085,RC02669	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
TLS2_k127_1010654_1	1100720.ALKN01000033_gene760	3.286e-69	237.0	COG1846@1|root,COG1846@2|Bacteria,1RCY7@1224|Proteobacteria,2VSV9@28216|Betaproteobacteria,4AERH@80864|Comamonadaceae	28216|Betaproteobacteria	K	TIGRFAM homoprotocatechuate degradation operon regulator, HpaR	hpaR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS2_k127_1010654_0	595537.Varpa_2326	8.525e-151	495.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2VJ5B@28216|Betaproteobacteria,4AC0Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
TLS2_k127_1010654_3	870187.Thini_2214	2.611e-19	94.0	COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,1S9PR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	enzyme involved in biosynthesis of extracellular polysaccharides	-	-	-	-	-	-	-	-	-	-	-	-	ABM
TLS2_k127_101066_3	987059.RBXJA2T_15503	1.246e-50	180.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,1KKNP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
TLS2_k127_101066_4	29581.BW37_02744	2.48e-42	158.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,474S4@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	4Fe-4S binding domain	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
TLS2_k127_101066_1	397945.Aave_3612	6.076e-89	298.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2VKKJ@28216|Betaproteobacteria,4ABYV@80864|Comamonadaceae	28216|Betaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
TLS2_k127_101066_0	987059.RBXJA2T_15523	3.342e-99	336.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,1KK92@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
TLS2_k127_101066_2	987059.RBXJA2T_15528	9.405e-81	271.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria,1KJRH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
TLS2_k127_101066_5	1157708.KB907458_gene1694	3.942e-10	60.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria,4ABG6@80864|Comamonadaceae	28216|Betaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
TLS2_k127_1026098_2	1408164.MOLA814_01454	1.341e-12	68.0	COG3090@1|root,COG3090@2|Bacteria,1MVKS@1224|Proteobacteria,2VRBP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TRAP-type C4-dicarboxylate transport system small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
TLS2_k127_1026098_1	709797.CSIRO_1637	1.19e-219	689.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,3JTXU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	MA20_30170	-	-	-	-	-	-	-	-	-	-	-	DctM
TLS2_k127_1026098_0	987059.RBXJA2T_04523	3.444e-256	799.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VIJX@28216|Betaproteobacteria,1KIXS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	matB	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
TLS2_k127_1026098_3	395495.Lcho_4277	3.905e-12	72.0	2CM4S@1|root,2ZQGG@2|Bacteria,1PAK6@1224|Proteobacteria,2W5A3@28216|Betaproteobacteria,1KP6X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Cysteine-rich CWC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CWC
TLS2_k127_1027508_1	397945.Aave_3099	1.948e-55	194.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,4AARH@80864|Comamonadaceae	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
TLS2_k127_1027508_0	1254432.SCE1572_09340	1.808e-117	386.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,42ND0@68525|delta/epsilon subdivisions,2WNKU@28221|Deltaproteobacteria,2YTTK@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF808)	-	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
TLS2_k127_1027508_2	269799.Gmet_1196	5.448e-55	202.0	COG2815@1|root,COG2815@2|Bacteria,1RIP7@1224|Proteobacteria,42XQG@68525|delta/epsilon subdivisions,2WT9P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
TLS2_k127_103626_4	983917.RGE_46090	3.774e-83	288.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,1KKWC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
TLS2_k127_103626_6	522306.CAP2UW1_1105	4.254e-57	217.0	COG0727@1|root,COG0727@2|Bacteria,1RCAS@1224|Proteobacteria,2VYAZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
TLS2_k127_103626_7	573413.Spirs_2005	1.686e-19	93.0	2DRHR@1|root,33BTC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_103626_5	1454004.AW11_03688	5.557e-59	211.0	COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,2VVUF@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
TLS2_k127_103626_3	1463857.JOFZ01000012_gene2058	6.132e-130	422.0	COG1893@1|root,COG1893@2|Bacteria,2I3AM@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
TLS2_k127_103626_2	452637.Oter_0963	8.989e-176	561.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	BT1,MFS_1
TLS2_k127_103626_0	883126.HMPREF9710_00916	0.0	1023.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2VJSU@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
TLS2_k127_103626_1	864051.BurJ1DRAFT_0296	2.444e-238	745.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,1KJ0G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	ABC transporter	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
TLS2_k127_1044754_0	522306.CAP2UW1_3300	2.46e-95	317.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,2VNCP@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS2_k127_1044754_1	522306.CAP2UW1_3301	2.371e-62	227.0	COG0642@1|root,COG0642@2|Bacteria,1MXK8@1224|Proteobacteria,2VP3X@28216|Betaproteobacteria	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS2_k127_1048095_1	395495.Lcho_0128	1.607e-77	263.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2VICZ@28216|Betaproteobacteria,1KIUQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241,2.3.1.242	ko:K02517,ko:K12974	ko00540,ko01100,map00540,map01100	M00060	R05146,R10906	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
TLS2_k127_1048095_0	395495.Lcho_0129	5.937e-118	385.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,1KJ10@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
TLS2_k127_1048095_2	1265502.KB905932_gene1943	9.221e-45	177.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,2VPN6@28216|Betaproteobacteria,4ACME@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
TLS2_k127_1050031_2	983917.RGE_24270	1.404e-103	348.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2VJZP@28216|Betaproteobacteria,1KJ83@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	peptidylprolyl isomerase	cbf2	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N_3
TLS2_k127_1050031_3	864051.BurJ1DRAFT_2263	5.126e-26	110.0	COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,2VVNP@28216|Betaproteobacteria,1KMJC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Belongs to the BolA IbaG family	bolA	-	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
TLS2_k127_1050031_4	983917.RGE_24300	0.0002382	50.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VSHQ@28216|Betaproteobacteria,1KM43@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
TLS2_k127_1050031_1	987059.RBXJA2T_08925	2.229e-218	690.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2VH7S@28216|Betaproteobacteria,1KIV6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
TLS2_k127_1050031_0	864051.BurJ1DRAFT_2271	5.896e-261	813.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,1KJ9F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	fadB	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
TLS2_k127_1050576_3	864051.BurJ1DRAFT_2067	1.351e-18	86.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2VIHG@28216|Betaproteobacteria,1KMB7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TLS2_k127_1050576_1	983917.RGE_00640	3.424e-241	749.0	COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,2VJE2@28216|Betaproteobacteria,1KJME@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0229 family	-	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
TLS2_k127_1050576_0	983917.RGE_00650	4.108e-314	968.0	COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,2VHJ7@28216|Betaproteobacteria,1KJEV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	SpoVR like protein	spoVR2	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
TLS2_k127_1050576_2	243365.CV_0365	8.298e-19	87.0	COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,2VM0X@28216|Betaproteobacteria,2KSQI@206351|Neisseriales	206351|Neisseriales	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
TLS2_k127_1054499_0	983917.RGE_31860	4.608e-94	315.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2VH04@28216|Betaproteobacteria,1KJZH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS2_k127_1054499_1	290398.Csal_1575	9.157e-76	269.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1XHN2@135619|Oceanospirillales	135619|Oceanospirillales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
TLS2_k127_1054499_2	187272.Mlg_1220	1.886e-23	106.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,1T1K1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	CBS domain	hrp1	-	-	-	-	-	-	-	-	-	-	-	CBS
TLS2_k127_1054499_3	243233.MCA2384	6.681e-23	98.0	COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,1XECA@135618|Methylococcales	135618|Methylococcales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
TLS2_k127_1065628_1	748247.AZKH_0219	1.569e-157	512.0	COG2703@1|root,COG4191@1|root,COG2703@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,2KVY4@206389|Rhodocyclales	206389|Rhodocyclales	PT	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Hemerythrin,HisKA
TLS2_k127_1065628_0	1163617.SCD_n02298	9.58e-181	572.0	COG2804@1|root,COG3437@1|root,COG2804@2|Bacteria,COG3437@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type II secretion system protein E	-	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	Response_reg,T2SSE,T2SSE_N
TLS2_k127_1066898_0	987059.RBXJA2T_17951	7.964e-195	614.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria,1KJG9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
TLS2_k127_1066898_1	983917.RGE_27480	6.337e-148	472.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,1KJ28@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
TLS2_k127_1066898_3	1265502.KB905935_gene3055	4.474e-18	85.0	COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,2WAPT@28216|Betaproteobacteria,4AFXA@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2065)	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
TLS2_k127_1066898_2	365046.Rta_19040	3.433e-81	281.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2VHVX@28216|Betaproteobacteria,4A9WQ@80864|Comamonadaceae	28216|Betaproteobacteria	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
TLS2_k127_1077127_0	1265502.KB905943_gene2759	3.113e-296	918.0	COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,2VHH2@28216|Betaproteobacteria,4AA15@80864|Comamonadaceae	28216|Betaproteobacteria	EG	Belongs to the IlvD Edd family	edd	-	4.2.1.12	ko:K01690	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00008	R02036	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
TLS2_k127_1077127_2	864051.BurJ1DRAFT_1587	2.031e-101	333.0	COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,2VQWM@28216|Betaproteobacteria,1KJU8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
TLS2_k127_1077127_1	614083.AWQR01000025_gene3713	6.248e-102	343.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,2VJ5U@28216|Betaproteobacteria	28216|Betaproteobacteria	S	RarD protein, DMT superfamily transporter	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
TLS2_k127_1077127_4	864051.BurJ1DRAFT_2879	2.957e-33	132.0	COG1977@1|root,COG1977@2|Bacteria,1N6RG@1224|Proteobacteria,2VVVJ@28216|Betaproteobacteria,1KMQE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
TLS2_k127_1077127_3	987059.RBXJA2T_14816	1.214e-87	313.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2VMA5@28216|Betaproteobacteria,1KK27@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1100798_2	983917.RGE_44700	1.931e-60	214.0	COG1279@1|root,COG1279@2|Bacteria,1QXRU@1224|Proteobacteria,2WH6P@28216|Betaproteobacteria	28216|Betaproteobacteria	S	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
TLS2_k127_1100798_0	983917.RGE_43320	3.182e-263	833.0	COG2176@1|root,COG5002@1|root,COG2176@2|Bacteria,COG5002@2|Bacteria,1QUVW@1224|Proteobacteria,2VHZ3@28216|Betaproteobacteria,1KNCN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	LT	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
TLS2_k127_1100798_3	1525715.IX54_00880	2.991e-50	183.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2U98H@28211|Alphaproteobacteria,2PX3I@265|Paracoccus	28211|Alphaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt,Response_reg
TLS2_k127_1100798_1	1265502.KB905946_gene1152	6.866e-116	380.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VKRS@28216|Betaproteobacteria,4AAXQ@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
TLS2_k127_1101718_3	395495.Lcho_0685	5.55e-90	302.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2VREV@28216|Betaproteobacteria,1KKNK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS2_k127_1101718_5	420662.Mpe_A1107	6.981e-58	203.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2VR2S@28216|Betaproteobacteria,1KKS7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
TLS2_k127_1101718_1	983917.RGE_13490	9.111e-126	406.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2VHPY@28216|Betaproteobacteria,1KJYY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
TLS2_k127_1101718_4	987059.RBXJA2T_05438	8.7e-64	231.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2VQ0H@28216|Betaproteobacteria,1KKVJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
TLS2_k127_1101718_8	983917.RGE_13470	1.148e-38	147.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2VTYP@28216|Betaproteobacteria,1KM8E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
TLS2_k127_1101718_6	983917.RGE_13450	7.619e-49	179.0	COG2314@1|root,COG2314@2|Bacteria,1RD84@1224|Proteobacteria,2VSV6@28216|Betaproteobacteria,1KM5W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
TLS2_k127_1101718_0	983917.RGE_13440	2.993e-181	572.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,1KJVK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Phosphate transporter family	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
TLS2_k127_1101718_2	987059.RBXJA2T_05418	1.64e-102	336.0	COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,2VKF1@28216|Betaproteobacteria,1KK30@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
TLS2_k127_1101718_7	983917.RGE_13410	4.408e-47	175.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2VSE2@28216|Betaproteobacteria,1KMF0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
TLS2_k127_1111191_2	420662.Mpe_A0070	1.317e-108	356.0	COG0861@1|root,COG0861@2|Bacteria,1MXSK@1224|Proteobacteria,2VHZ5@28216|Betaproteobacteria,1KK70@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
TLS2_k127_1111191_4	987059.RBXJA2T_13494	2.235e-66	248.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,1KJ47@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KLT	PFAM Protein kinase	-	-	2.7.11.1	ko:K11912,ko:K12132	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	HAMP,Pkinase
TLS2_k127_1111191_0	864051.BurJ1DRAFT_4944	1.573e-120	407.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria,1KKAB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	phosphatase	pppL	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
TLS2_k127_1111191_1	987059.RBXJA2T_13484	9.191e-109	356.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,1KJ7M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
TLS2_k127_1111191_3	864051.BurJ1DRAFT_4942	2.982e-93	312.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,2VH0D@28216|Betaproteobacteria,1KK52@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	cAMP phosphodiesterases class-II	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
TLS2_k127_1111806_3	987059.RBXJA2T_07010	4.779e-109	366.0	COG0477@1|root,COG2814@2|Bacteria,1R3YS@1224|Proteobacteria,2VQBS@28216|Betaproteobacteria,1KNDV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS2_k127_1111806_1	983917.RGE_10570	7.029e-203	640.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2VJ84@28216|Betaproteobacteria,1KJ4N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
TLS2_k127_1111806_2	1198452.Jab_2c05080	3.882e-161	522.0	COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,1MYCW@1224|Proteobacteria,2WF6V@28216|Betaproteobacteria,476HS@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA
TLS2_k127_1111806_0	983917.RGE_10540	0.0	1571.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,1KITH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
TLS2_k127_1111806_4	420662.Mpe_A2745	1.415e-70	243.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VKR8@28216|Betaproteobacteria,1KIZM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	peptidase	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
TLS2_k127_1128500_2	420662.Mpe_A0218	1.255e-73	252.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,1KK29@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
TLS2_k127_1128500_4	864051.BurJ1DRAFT_4653	4.819e-46	173.0	COG2980@1|root,COG2980@2|Bacteria,1N13K@1224|Proteobacteria,2VU54@28216|Betaproteobacteria,1KM9B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
TLS2_k127_1128500_0	987059.RBXJA2T_02847	3.96e-157	504.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,2VIKX@28216|Betaproteobacteria,1KJ0R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
TLS2_k127_1128500_1	983917.RGE_45530	8.741e-148	476.0	COG1744@1|root,COG1744@2|Bacteria,1NGHH@1224|Proteobacteria,2VNN9@28216|Betaproteobacteria,1KJRT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
TLS2_k127_1128500_3	983917.RGE_45540	9.072e-57	214.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,2WGJY@28216|Betaproteobacteria,1KKHB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
TLS2_k127_1163330_3	864051.BurJ1DRAFT_1748	1.412e-40	152.0	COG3807@1|root,COG3807@2|Bacteria,1RE8W@1224|Proteobacteria,2W17I@28216|Betaproteobacteria,1KN07@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
TLS2_k127_1163330_1	420662.Mpe_A1220	1.367e-65	236.0	COG3637@1|root,COG3637@2|Bacteria,1RDPZ@1224|Proteobacteria,2W2BF@28216|Betaproteobacteria,1KNIB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1163330_2	864051.BurJ1DRAFT_1746	4.575e-58	210.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,2WF1B@28216|Betaproteobacteria,1KPKM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CO	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1163330_0	420662.Mpe_A1222	6.294e-133	436.0	COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria	1224|Proteobacteria	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
TLS2_k127_1181159_0	1100721.ALKO01000031_gene111	1.949e-242	756.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2VI73@28216|Betaproteobacteria,4ABXD@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM monooxygenase FAD-binding	-	-	1.14.13.127	ko:K05712	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06786,R06787	RC00236	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
TLS2_k127_1194875_0	395495.Lcho_0279	4.588e-144	466.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2VHIM@28216|Betaproteobacteria,1KMV9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	arcB	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
TLS2_k127_1194875_1	395495.Lcho_0278	6.587e-20	103.0	COG1522@1|root,COG1522@2|Bacteria,1RE5H@1224|Proteobacteria,2VS27@28216|Betaproteobacteria,1KMQH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
TLS2_k127_1201798_3	450851.PHZ_c1570	1.123e-32	131.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2TRZF@28211|Alphaproteobacteria,2KFJW@204458|Caulobacterales	204458|Caulobacterales	S	PFAM peptidase M61 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
TLS2_k127_1201798_1	987059.RBXJA2T_16917	2.208e-123	400.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VKRU@28216|Betaproteobacteria,1KKDY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
TLS2_k127_1201798_4	983917.RGE_01630	4.488e-29	117.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,2VVV6@28216|Betaproteobacteria,1KMKD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Zinc-finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
TLS2_k127_1201798_0	1100720.ALKN01000033_gene764	6.183e-177	558.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria,4A9UB@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS2_k127_1201798_2	983917.RGE_01670	2.624e-64	221.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria,1KIWT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
TLS2_k127_1229405_1	1122599.AUGR01000021_gene3188	1.797e-99	332.0	COG3437@1|root,COG3437@2|Bacteria,1QW6V@1224|Proteobacteria,1T34X@1236|Gammaproteobacteria,1XRSJ@135619|Oceanospirillales	135619|Oceanospirillales	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
TLS2_k127_1229405_0	614083.AWQR01000025_gene3760	1.614e-153	511.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VHPI@28216|Betaproteobacteria,4AAUI@80864|Comamonadaceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,dCache_3
TLS2_k127_1229405_3	398578.Daci_0725	3.541e-73	267.0	2C5G6@1|root,33Q77@2|Bacteria,1PVA5@1224|Proteobacteria,2WB6H@28216|Betaproteobacteria,4AH0P@80864|Comamonadaceae	28216|Betaproteobacteria	S	Sel1 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1229405_2	1265502.KB905940_gene3020	3.727e-89	306.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2VHFA@28216|Betaproteobacteria,4AAC9@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	GO:0003674,GO:0003824,GO:0004362,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0015949,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0022900,GO:0031974,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0055114,GO:0070013,GO:0070887,GO:0071704,GO:0097237,GO:0098754,GO:0098869,GO:1901360,GO:1990748	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS2_k127_1230929_0	935863.AWZR01000002_gene1088	3.822e-109	370.0	COG0457@1|root,COG0515@1|root,COG3063@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3063@2|Bacteria,1MVEU@1224|Proteobacteria,1S0IU@1236|Gammaproteobacteria,1X52Q@135614|Xanthomonadales	135614|Xanthomonadales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12,TPR_8
TLS2_k127_1230929_1	1538295.JY96_11890	8.662e-52	190.0	COG1595@1|root,COG1595@2|Bacteria,1N3BR@1224|Proteobacteria,2VV6Y@28216|Betaproteobacteria,1KM9X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
TLS2_k127_1230929_2	1144305.PMI02_04335	3.274e-08	62.0	COG5001@1|root,COG5001@2|Bacteria,1QUGW@1224|Proteobacteria,2TZ4Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
TLS2_k127_1232450_1	358220.C380_23050	3.03e-167	531.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VJGC@28216|Betaproteobacteria,4AC8V@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
TLS2_k127_1232450_5	987059.RBXJA2T_15338	2.89e-77	262.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,2VS28@28216|Betaproteobacteria,1KKPZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome B561	cybB	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
TLS2_k127_1232450_7	987059.RBXJA2T_15333	1.129e-64	229.0	COG2353@1|root,COG2353@2|Bacteria,1RJFZ@1224|Proteobacteria,2VQHC@28216|Betaproteobacteria,1KKZG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS2_k127_1232450_4	420662.Mpe_A3508	1.678e-77	264.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2VQTQ@28216|Betaproteobacteria,1KKJR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS2_k127_1232450_8	420662.Mpe_A3509	8.38e-56	203.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2W2SU@28216|Betaproteobacteria,1KNNH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS2_k127_1232450_2	1100720.ALKN01000024_gene1422	3.5e-151	487.0	COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2VHEX@28216|Betaproteobacteria,4ABVA@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
TLS2_k127_1232450_6	1038866.KB902835_gene477	1.007e-67	235.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2U4QB@28211|Alphaproteobacteria,3JRDA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
TLS2_k127_1232450_0	1207063.P24_05264	4.591e-189	607.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,2JQ0Z@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
TLS2_k127_1232450_3	1304877.KI519399_gene2903	9.842e-144	469.0	COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,3JVBW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
TLS2_k127_1240110_2	987059.RBXJA2T_05823	4.158e-129	417.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2VJ68@28216|Betaproteobacteria,1KJSB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
TLS2_k127_1240110_0	420662.Mpe_A2773	3.717e-204	637.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria,1KJTM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TLS2_k127_1240110_1	420662.Mpe_A2772	6.207e-130	423.0	COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2VMEV@28216|Betaproteobacteria,1KIZ7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
TLS2_k127_1240110_3	1286106.MPL1_10067	2.385e-11	64.0	2DMND@1|root,32SNQ@2|Bacteria,1R37A@1224|Proteobacteria,1T64B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1245468_0	987059.RBXJA2T_05783	2.508e-110	361.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,1MVKX@1224|Proteobacteria,2VHW5@28216|Betaproteobacteria,1KN4Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Alpha amylase catalytic region	treS	-	3.2.1.1,3.2.1.10,3.2.1.20,5.4.99.16	ko:K01182,ko:K01187,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01557,R01718,R01791,R02108,R02112,R06087,R06088,R06199,R11262	RC00028,RC00049,RC00059,RC00077,RC00451,RC01816	ko00000,ko00001,ko01000	-	GH13,GH31	-	APH,Alpha-amylase,Malt_amylase_C
TLS2_k127_1245468_1	338969.Rfer_1154	3.104e-60	216.0	COG1846@1|root,COG1846@2|Bacteria,1PW9W@1224|Proteobacteria,2VUDE@28216|Betaproteobacteria,4AID2@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS2_k127_1245468_2	614083.AWQR01000047_gene3301	4.296e-44	163.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VSP6@28216|Betaproteobacteria,4ADHE@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
TLS2_k127_1256823_3	887062.HGR_03257	2.173e-56	200.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2VH97@28216|Betaproteobacteria,4AB6N@80864|Comamonadaceae	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
TLS2_k127_1256823_0	395495.Lcho_1704	0.0	1081.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2VH2W@28216|Betaproteobacteria,1KJBB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
TLS2_k127_1256823_2	987059.RBXJA2T_19271	7.483e-115	380.0	COG0697@1|root,COG0697@2|Bacteria,1RFZW@1224|Proteobacteria,2VJS5@28216|Betaproteobacteria,1KJ5V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS2_k127_1256823_1	864051.BurJ1DRAFT_2670	1.133e-166	541.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,2VMJZ@28216|Betaproteobacteria,1KN20@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
TLS2_k127_1256823_4	864051.BurJ1DRAFT_2669	2.189e-45	168.0	COG1075@1|root,COG1075@2|Bacteria,1NJNA@1224|Proteobacteria,2VPNT@28216|Betaproteobacteria,1KNTZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,PGAP1
TLS2_k127_1262444_4	426114.THI_1258	7.625e-26	108.0	COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,2VIP0@28216|Betaproteobacteria,1KJVJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
TLS2_k127_1262444_2	296591.Bpro_3588	3.401e-97	323.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,2VHG4@28216|Betaproteobacteria,4ABNH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation	kynB	GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
TLS2_k127_1262444_3	983917.RGE_14600	1.687e-56	202.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2VRN8@28216|Betaproteobacteria,1KM7Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
TLS2_k127_1262444_1	987059.RBXJA2T_01765	3.982e-118	385.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2VK1G@28216|Betaproteobacteria,1KJ92@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33,6.3.4.15	ko:K01947,ko:K03525	ko00770,ko00780,ko01100,map00770,map00780,map01100	M00120	R01074,R02971,R03018,R04391,R05145	RC00002,RC00017,RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko00002,ko01000	-	-	-	BPL_C,BPL_LplA_LipB,Pan_kinase
TLS2_k127_1262444_0	983917.RGE_43760	1.148e-120	392.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VH05@28216|Betaproteobacteria,1KJWN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
TLS2_k127_1277514_3	987059.RBXJA2T_09722	0.0004604	43.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,1KK41@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
TLS2_k127_1277514_2	864051.BurJ1DRAFT_2462	4.387e-131	439.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria,1KIYG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
TLS2_k127_1277514_1	420662.Mpe_A1273	7.618e-162	517.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria,1KJ4T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
TLS2_k127_1277514_0	987059.RBXJA2T_09707	2.303e-179	569.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2VIJV@28216|Betaproteobacteria,1KIUZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
TLS2_k127_1277514_4	472175.EL18_02582	0.0004827	44.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
TLS2_k127_130873_0	857087.Metme_4407	2.997e-138	449.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,1S6C7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Esterase PHB depolymerase	lpqC	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase_phd
TLS2_k127_130873_1	543728.Vapar_5277	1.522e-57	203.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,4ABUM@80864|Comamonadaceae	28216|Betaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
TLS2_k127_1327337_0	864051.BurJ1DRAFT_0787	4.397e-257	797.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2VIJH@28216|Betaproteobacteria,1KN5N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	NMT1-like family	nrtA	-	-	ko:K02051,ko:K15576	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17	-	-	NMT1_2
TLS2_k127_1327337_3	864051.BurJ1DRAFT_0788	5.115e-92	308.0	COG2197@1|root,COG2197@2|Bacteria,1RBNA@1224|Proteobacteria,2WF1D@28216|Betaproteobacteria,1KPKN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS2_k127_1327337_1	420662.Mpe_A3495	8.845e-175	556.0	COG4585@1|root,COG4585@2|Bacteria,1R46Q@1224|Proteobacteria,2WEVP@28216|Betaproteobacteria,1KPF6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS,PAS_9
TLS2_k127_1327337_4	760192.Halhy_4054	3.095e-46	175.0	COG4845@1|root,COG4845@2|Bacteria,4NPDG@976|Bacteroidetes,1IS3J@117747|Sphingobacteriia	976|Bacteroidetes	V	Chloramphenicol acetyltransferase	cat	-	2.3.1.28	ko:K19271	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CAT
TLS2_k127_1327337_2	340.xcc-b100_4049	1.939e-149	482.0	COG1835@1|root,COG1835@2|Bacteria,1REU1@1224|Proteobacteria,1SYFD@1236|Gammaproteobacteria,1X5EU@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyltransferase	oac	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS2_k127_1358532_1	987059.RBXJA2T_18156	2.626e-122	397.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2VJW8@28216|Betaproteobacteria,1KJIW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc
TLS2_k127_1358532_3	983917.RGE_27080	1.248e-35	139.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	GAF,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
TLS2_k127_1358532_0	987059.RBXJA2T_18146	3.531e-160	518.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2VH7Z@28216|Betaproteobacteria,1KK2P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
TLS2_k127_1358532_2	983917.RGE_27100	4.636e-39	149.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2VTY8@28216|Betaproteobacteria,1KM5P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Ribosome-associated heat shock protein	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
TLS2_k127_1365723_0	987059.RBXJA2T_15188	1.957e-247	771.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,1KJHF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
TLS2_k127_1365723_5	864051.BurJ1DRAFT_4015	2.618e-111	365.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2VI1U@28216|Betaproteobacteria,1KJSX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	ThiF family	thiF	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
TLS2_k127_1365723_3	983917.RGE_37660	5.57e-143	458.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2VK4I@28216|Betaproteobacteria,1KJJK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
TLS2_k127_1365723_2	987059.RBXJA2T_15173	3.987e-177	557.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2VJU2@28216|Betaproteobacteria,1KIWQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the arginase family	rocF	-	3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7	ko:K01476,ko:K01480,ko:K12255,ko:K18459	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157,R01990	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS2_k127_1365723_1	864051.BurJ1DRAFT_0518	9.361e-207	652.0	COG0265@1|root,COG0265@2|Bacteria,1NXB0@1224|Proteobacteria,2VJB7@28216|Betaproteobacteria,1KN05@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
TLS2_k127_1365723_6	114615.BRADO4142	2.512e-21	107.0	COG1716@1|root,COG1716@2|Bacteria,1MXT7@1224|Proteobacteria,2U0R7@28211|Alphaproteobacteria,3JRHD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	Yop-YscD_cpl
TLS2_k127_1365723_4	987059.RBXJA2T_15158	2.049e-114	374.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2VMMI@28216|Betaproteobacteria,1KK6K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Peptidase C26	-	-	4.1.3.27	ko:K01658,ko:K07010	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Peptidase_C26
TLS2_k127_1373980_7	987059.RBXJA2T_13649	1.114e-35	142.0	COG4970@1|root,COG4970@2|Bacteria,1NA2G@1224|Proteobacteria,2VWT2@28216|Betaproteobacteria,1KMTA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084,ko:K08085	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
TLS2_k127_1373980_9	983917.RGE_16870	5.83e-26	121.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
TLS2_k127_1373980_5	983917.RGE_16880	1.384e-84	295.0	COG5581@1|root,COG5581@2|Bacteria,1RFI4@1224|Proteobacteria,2W8A4@28216|Betaproteobacteria,1KKKD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility	ycgR	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR
TLS2_k127_1373980_6	983917.RGE_16890	1.429e-40	152.0	COG1516@1|root,COG1516@2|Bacteria,1N4VX@1224|Proteobacteria,2VU8N@28216|Betaproteobacteria,1KM8H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar protein FliT	fliT	-	-	ko:K02423	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliT
TLS2_k127_1373980_8	1265502.KB905929_gene2162	1.172e-30	126.0	COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,2VU2S@28216|Betaproteobacteria,4AF1I@80864|Comamonadaceae	28216|Betaproteobacteria	N	flagellar protein FliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
TLS2_k127_1373980_2	864051.BurJ1DRAFT_1317	1.05e-111	377.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,2VHMK@28216|Betaproteobacteria,1KK2R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
TLS2_k127_1373980_4	232721.Ajs_3812	9.426e-99	330.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,2VJTA@28216|Betaproteobacteria,4ADS1@80864|Comamonadaceae	28216|Betaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
TLS2_k127_1373980_3	232721.Ajs_3813	7.471e-101	340.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,2VJTA@28216|Betaproteobacteria,4ADS1@80864|Comamonadaceae	28216|Betaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
TLS2_k127_1373980_1	864051.BurJ1DRAFT_1762	7.634e-125	408.0	COG2267@1|root,COG2267@2|Bacteria,1RATF@1224|Proteobacteria,2WI63@28216|Betaproteobacteria,1KJSE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS2_k127_1373980_0	1286631.X805_11040	0.0	1116.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria,1KJE9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
TLS2_k127_1382097_0	864051.BurJ1DRAFT_3327	2.934e-271	839.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,1KKEG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADPH-dependent glutamate synthase beta	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_21,Fer4_7,Pyr_redox_2,Pyr_redox_3
TLS2_k127_1382097_4	864051.BurJ1DRAFT_3326	6.334e-36	151.0	2E6CU@1|root,3310G@2|Bacteria,1N0TM@1224|Proteobacteria,2VV3Z@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1382097_2	864051.BurJ1DRAFT_3325	6.611e-125	404.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
TLS2_k127_1382097_1	864051.BurJ1DRAFT_3324	6.065e-175	555.0	COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,2VK76@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
TLS2_k127_1382097_3	864051.BurJ1DRAFT_3323	1.437e-78	292.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,2VI93@28216|Betaproteobacteria,1KKQX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
TLS2_k127_1394589_1	1123504.JQKD01000035_gene2691	7.722e-91	312.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,2VJR4@28216|Betaproteobacteria,4ADHQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	protein, hemolysin III	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
TLS2_k127_1394589_2	983917.RGE_21430	2.402e-33	134.0	COG0526@1|root,COG0526@2|Bacteria,1N8B0@1224|Proteobacteria,2VW5T@28216|Betaproteobacteria,1KMU9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CO	Thioredoxin	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Thioredoxin
TLS2_k127_1394589_0	1265502.KB905934_gene3210	9.682e-110	359.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2VIQZ@28216|Betaproteobacteria,4AAD7@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
TLS2_k127_1401420_4	543728.Vapar_5069	6.125e-130	423.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria,4ACTD@80864|Comamonadaceae	28216|Betaproteobacteria	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
TLS2_k127_1401420_0	983917.RGE_01000	1.266e-210	660.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria,1KJWX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
TLS2_k127_1401420_2	864051.BurJ1DRAFT_0699	7.208e-136	437.0	COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,2VJ19@28216|Betaproteobacteria,1KKHA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Belongs to the hyi family	hyi	-	5.3.1.22,5.3.1.35	ko:K01816,ko:K22131	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
TLS2_k127_1401420_3	983917.RGE_01020	1.238e-130	422.0	COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,2VHM4@28216|Betaproteobacteria,1KJEC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Specifically methylates the adenine in position 2030 of 23S rRNA	rlmJ	-	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
TLS2_k127_1401420_1	987059.RBXJA2T_05258	3.496e-171	545.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2VH2S@28216|Betaproteobacteria,1KJIJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADH flavin oxidoreductase NADH oxidase	nemA	GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
TLS2_k127_1408240_0	983917.RGE_15160	1.884e-201	631.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria,1KJVT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
TLS2_k127_1408240_1	983917.RGE_15150	1.791e-148	473.0	COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,2VHD7@28216|Betaproteobacteria,1KKEW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	PFAM 20S proteasome, A and B subunits	-	-	-	ko:K07395	-	-	-	-	ko00000	-	-	-	Proteasome
TLS2_k127_1408240_2	1235457.C404_21450	1.405e-98	337.0	COG3608@1|root,COG3608@2|Bacteria,1MV55@1224|Proteobacteria,2VIYJ@28216|Betaproteobacteria,1K2I3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Succinylglutamate desuccinylase	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
TLS2_k127_1408240_3	568706.BN118_2898	1.478e-77	267.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2VN37@28216|Betaproteobacteria,3T8PH@506|Alcaligenaceae	28216|Betaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	3.5.1.68	ko:K01458	ko00340,ko00630,map00340,map00630	-	R00525	RC00165,RC00323	ko00000,ko00001,ko01000	-	-	-	FGase
TLS2_k127_1421572_2	1249627.D779_3169	7.211e-09	60.0	COG2002@1|root,COG2002@2|Bacteria,1N5YP@1224|Proteobacteria,1SBID@1236|Gammaproteobacteria,1WYVQ@135613|Chromatiales	135613|Chromatiales	K	TIGRFAM looped-hinge helix DNA binding domain, AbrB family	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
TLS2_k127_1421572_1	983920.Y88_2914	2.988e-27	115.0	COG5611@1|root,COG5611@2|Bacteria,1RDUI@1224|Proteobacteria,2U8YA@28211|Alphaproteobacteria,2KCEP@204457|Sphingomonadales	204457|Sphingomonadales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
TLS2_k127_1421572_0	452637.Oter_2603	1.614e-140	469.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
TLS2_k127_1426934_1	987059.RBXJA2T_12757	1.299e-182	584.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH5A@28216|Betaproteobacteria,1KJIS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
TLS2_k127_1426934_5	983917.RGE_15740	1e-35	139.0	COG3308@1|root,COG3308@2|Bacteria,1N1EF@1224|Proteobacteria,2VU3C@28216|Betaproteobacteria,1KMGX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2069
TLS2_k127_1426934_6	269482.Bcep1808_4077	8.653e-07	61.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,1K4GX@119060|Burkholderiaceae	28216|Betaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406,ko:K03776,ko:K05874,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3,TarH,sCache_2
TLS2_k127_1426934_2	987059.RBXJA2T_12767	3.204e-162	523.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,2VJNM@28216|Betaproteobacteria,1KJDV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	UPF0761 membrane protein	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
TLS2_k127_1426934_3	983917.RGE_15810	1.15e-91	325.0	COG2267@1|root,COG2267@2|Bacteria,1Q6AF@1224|Proteobacteria,2VJQ3@28216|Betaproteobacteria,1KKJS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,FSH1
TLS2_k127_1426934_0	1268622.AVS7_01093	2.743e-234	734.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2VHYA@28216|Betaproteobacteria,4AB52@80864|Comamonadaceae	28216|Betaproteobacteria	E	TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
TLS2_k127_1426934_4	987059.RBXJA2T_12812	5.93e-69	237.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2VQEB@28216|Betaproteobacteria,1KKNW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
TLS2_k127_1432292_2	338969.Rfer_1099	4.717e-68	235.0	COG1653@1|root,COG1653@2|Bacteria,1PCRV@1224|Proteobacteria,2VN28@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
TLS2_k127_1432292_0	338969.Rfer_1100	8.552e-141	453.0	COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,2VP73@28216|Betaproteobacteria,4AD3G@80864|Comamonadaceae	28216|Betaproteobacteria	P	binding-protein-dependent transport systems inner membrane component	ugpA_1	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K17242,ko:K17245	ko02010,map02010	M00196,M00198,M00207,M00600,M00601	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28,3.A.1.1.3,3.A.1.1.39,3.A.1.1.40	-	-	BPD_transp_1
TLS2_k127_1432292_1	338969.Rfer_1101	1.021e-84	285.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,2WEEU@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K05815,ko:K17246	ko02010,map02010	M00198,M00207,M00601	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3,3.A.1.1.40	-	-	BPD_transp_1
TLS2_k127_1441987_1	864051.BurJ1DRAFT_4709	1.049e-51	190.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2VH62@28216|Betaproteobacteria,1KKH3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD
TLS2_k127_1441987_0	864051.BurJ1DRAFT_0888	3.557e-74	258.0	29KMP@1|root,307IZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
TLS2_k127_1441987_2	1122604.JONR01000042_gene3451	4.603e-46	179.0	2EBUX@1|root,335UE@2|Bacteria,1NAYE@1224|Proteobacteria,1T8Q1@1236|Gammaproteobacteria,1XB2A@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1441987_3	987059.RBXJA2T_04668	5.775e-38	147.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2VHXI@28216|Betaproteobacteria,1KK9X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis	deoA	-	2.4.2.4	ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
TLS2_k127_1442562_3	1286631.X805_40960	1.011e-15	79.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,1KK7A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
TLS2_k127_1442562_0	987059.RBXJA2T_03416	2.364e-272	842.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VHSH@28216|Betaproteobacteria,1KIWD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
TLS2_k127_1442562_1	1123504.JQKD01000046_gene1187	7.6e-70	243.0	COG0500@1|root,COG0500@2|Bacteria,1RDHE@1224|Proteobacteria,2VQIP@28216|Betaproteobacteria,4ADJ0@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
TLS2_k127_1442562_2	1157708.KB907458_gene1876	1.467e-59	209.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2VHF1@28216|Betaproteobacteria,4A9TM@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
TLS2_k127_1458278_0	983917.RGE_33000	9.091e-190	621.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,1KJYI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
TLS2_k127_1458278_1	983917.RGE_33010	3.427e-186	587.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,1KKDQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
TLS2_k127_1458278_2	864051.BurJ1DRAFT_2472	6.704e-26	109.0	COG0515@1|root,COG1639@1|root,COG0515@2|Bacteria,COG1639@2|Bacteria,1NJC4@1224|Proteobacteria,2VHRZ@28216|Betaproteobacteria,1KKRA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Pkinase
TLS2_k127_1476971_1	864051.BurJ1DRAFT_3183	4.043e-89	297.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VHM2@28216|Betaproteobacteria,1KMDY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS2_k127_1476971_0	864051.BurJ1DRAFT_3182	1.845e-207	651.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria,1KJWB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS2_k127_1478878_2	983917.RGE_18510	3.819e-72	246.0	COG0454@1|root,COG0456@2|Bacteria,1RCYQ@1224|Proteobacteria,2WGJZ@28216|Betaproteobacteria,1KMVM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS2_k127_1478878_1	987059.RBXJA2T_05848	6.224e-127	417.0	COG2206@1|root,COG2206@2|Bacteria,1RGJH@1224|Proteobacteria,2VSRC@28216|Betaproteobacteria,1KKXM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
TLS2_k127_1478878_0	1265502.KB905929_gene2205	2.144e-283	883.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJ5E@28216|Betaproteobacteria,4ACGG@80864|Comamonadaceae	28216|Betaproteobacteria	I	AMP-binding enzyme	bclA_2	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS2_k127_1482217_0	296591.Bpro_0919	3.894e-281	870.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2VKBR@28216|Betaproteobacteria,4ADDM@80864|Comamonadaceae	28216|Betaproteobacteria	C	Proton-conducting membrane transporter	hyfF	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
TLS2_k127_1482217_2	296591.Bpro_0918	9.468e-107	351.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,2VJTI@28216|Betaproteobacteria,4AC7I@80864|Comamonadaceae	28216|Betaproteobacteria	C	hydrogenase 4 membrane	hyfE	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
TLS2_k127_1482217_1	381666.H16_A2197	2.69e-116	377.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,2VKBD@28216|Betaproteobacteria,1K556@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NADH dehydrogenase	hyfD	-	-	-	-	-	-	-	-	-	-	-	NADHdh
TLS2_k127_151221_0	987059.RBXJA2T_16537	7.587e-131	419.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2VHGP@28216|Betaproteobacteria,1KK6S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
TLS2_k127_151221_1	983917.RGE_13950	1.294e-75	265.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,2VS13@28216|Betaproteobacteria,1KKJU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	HAD-hyrolase-like	gph	-	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
TLS2_k127_151221_2	596152.DesU5LDRAFT_1391	1.491e-19	89.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,42N7I@68525|delta/epsilon subdivisions,2WKY2@28221|Deltaproteobacteria,2M8MH@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
TLS2_k127_1512579_2	864051.BurJ1DRAFT_4399	5.279e-33	127.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2VH08@28216|Betaproteobacteria,1KJC7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
TLS2_k127_1512579_1	864051.BurJ1DRAFT_4400	2.935e-88	296.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2VRBQ@28216|Betaproteobacteria,1KKD6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
TLS2_k127_1512579_0	420662.Mpe_A3346	1.699e-118	382.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VI87@28216|Betaproteobacteria,1KJJ2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
TLS2_k127_1539501_1	987059.RBXJA2T_00610	1.472e-113	374.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,2VIU6@28216|Betaproteobacteria,1KJIU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
TLS2_k127_1539501_4	864051.BurJ1DRAFT_0267	4.584e-26	111.0	COG3190@1|root,COG3190@2|Bacteria,1NHJX@1224|Proteobacteria,2W9KI@28216|Betaproteobacteria,1KMGP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar biosynthesis protein, FliO	fliO	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
TLS2_k127_1539501_2	987059.RBXJA2T_00620	3.503e-64	222.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,2VSZ7@28216|Betaproteobacteria,1KKUP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar motor switch protein fliN	fliN	-	-	ko:K02417,ko:K03225	ko02030,ko02040,ko03070,map02030,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	FliMN_C
TLS2_k127_1539501_0	987059.RBXJA2T_00625	8.621e-189	596.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,2VI0A@28216|Betaproteobacteria,1KK5A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar motor switch	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
TLS2_k127_1539501_3	987059.RBXJA2T_00630	1.45e-59	212.0	COG1580@1|root,COG1580@2|Bacteria,1RARK@1224|Proteobacteria,2VTGH@28216|Betaproteobacteria,1KKTE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Controls the rotational direction of flagella during chemotaxis	fliL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
TLS2_k127_1546784_1	765420.OSCT_1706	3.599e-127	421.0	COG0477@1|root,COG2814@2|Bacteria,2G68C@200795|Chloroflexi,3781C@32061|Chloroflexia	32061|Chloroflexia	EGP	major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS2_k127_1546784_3	1123508.JH636440_gene2903	1.939e-57	212.0	COG0745@1|root,COG0745@2|Bacteria,2J32S@203682|Planctomycetes	203682|Planctomycetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS2_k127_1546784_2	765911.Thivi_1319	1.004e-115	391.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	pdhS	-	2.7.13.1,2.7.13.3	ko:K05962,ko:K07716	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_7,PAS_8,PAS_9
TLS2_k127_1546784_0	987059.RBXJA2T_01185	4.015e-158	513.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,2VHW5@28216|Betaproteobacteria,1KN4Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Alpha amylase catalytic region	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
TLS2_k127_1579328_1	338969.Rfer_0020	6.233e-110	368.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VIIX@28216|Betaproteobacteria,4AAH8@80864|Comamonadaceae	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS2_k127_1579328_2	983917.RGE_07840	7.497e-110	370.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VMKT@28216|Betaproteobacteria,1KPHY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS2_k127_1579328_3	983917.RGE_07830	2.797e-63	241.0	COG3495@1|root,COG3495@2|Bacteria,1RB8H@1224|Proteobacteria,2VSUS@28216|Betaproteobacteria,1KM0X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3299)	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	DUF3299
TLS2_k127_1579328_0	987059.RBXJA2T_17127	3.43e-184	587.0	COG0577@1|root,COG0577@2|Bacteria,1MVN1@1224|Proteobacteria,2VJWZ@28216|Betaproteobacteria,1KJSM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS2_k127_1579328_4	305700.B447_19139	2.197e-15	76.0	COG1136@1|root,COG1136@2|Bacteria,1RA1K@1224|Proteobacteria,2VQ4I@28216|Betaproteobacteria,2KYJQ@206389|Rhodocyclales	206389|Rhodocyclales	V	COG1136 ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS2_k127_1582299_0	864051.BurJ1DRAFT_2972	3.902e-316	971.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,1KJXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
TLS2_k127_1582299_2	987059.RBXJA2T_19071	1.565e-164	521.0	COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,2VH48@28216|Betaproteobacteria,1KJPP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
TLS2_k127_1582299_1	987059.RBXJA2T_19076	3.378e-257	799.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VGZD@28216|Betaproteobacteria,1KITG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
TLS2_k127_1588081_1	864051.BurJ1DRAFT_0544	3.923e-37	158.0	28WBH@1|root,2ZIBX@2|Bacteria,1PBRG@1224|Proteobacteria,2W6EA@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1588081_0	864051.BurJ1DRAFT_0545	5.011e-137	442.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,2VIYQ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_2
TLS2_k127_1596765_2	420662.Mpe_A0797	8.304e-25	116.0	COG1975@1|root,COG1975@2|Bacteria,1R3RT@1224|Proteobacteria,2VKME@28216|Betaproteobacteria,1KJ5R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	TIGRFAM xanthine dehydrogenase accessory protein XdhC	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
TLS2_k127_1596765_0	1502852.FG94_02191	0.0	1045.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2VHYR@28216|Betaproteobacteria,4735A@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	xdhB	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
TLS2_k127_1596765_1	596153.Alide_1071	1.288e-115	379.0	COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,2VI0J@28216|Betaproteobacteria,4AAFW@80864|Comamonadaceae	28216|Betaproteobacteria	C	CO dehydrogenase flavoprotein domain protein	xdhA	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
TLS2_k127_1597736_0	983917.RGE_34670	2.436e-307	947.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,2VKKZ@28216|Betaproteobacteria,1KJ9V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
TLS2_k127_1597736_1	987059.RBXJA2T_04058	1.337e-36	148.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,2VJEU@28216|Betaproteobacteria,1KJV9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
TLS2_k127_1602165_8	983917.RGE_28090	1.268e-11	65.0	2E95F@1|root,333E6@2|Bacteria,1N8N7@1224|Proteobacteria,2VWX5@28216|Betaproteobacteria,1KMN7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3619)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3619
TLS2_k127_1602165_7	987059.RBXJA2T_19216	2.12e-52	195.0	2E3UK@1|root,32YRY@2|Bacteria,1N74J@1224|Proteobacteria,2VVQ2@28216|Betaproteobacteria,1KM76@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3106)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
TLS2_k127_1602165_6	987059.RBXJA2T_19221	2.069e-55	203.0	COG1714@1|root,COG1714@2|Bacteria,1REEC@1224|Proteobacteria,2VRE0@28216|Betaproteobacteria,1KM4U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
TLS2_k127_1602165_4	983917.RGE_28130	2.216e-86	289.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2VRA6@28216|Betaproteobacteria,1KKNM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
TLS2_k127_1602165_5	987059.RBXJA2T_19236	1.823e-60	210.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,1KKXH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
TLS2_k127_1602165_1	987059.RBXJA2T_19241	8.17e-288	891.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2VJ8C@28216|Betaproteobacteria,1KJCK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
TLS2_k127_1602165_2	983917.RGE_28160	1.226e-168	537.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2VH0Z@28216|Betaproteobacteria,1KIYB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
TLS2_k127_1602165_3	983917.RGE_28170	7.071e-103	336.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2VQC0@28216|Betaproteobacteria,1KJXW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
TLS2_k127_1602165_0	983917.RGE_28180	0.0	1147.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,1KJEG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
TLS2_k127_1607482_1	358220.C380_03985	5.193e-151	486.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,2VI6W@28216|Betaproteobacteria,4AA2Q@80864|Comamonadaceae	28216|Betaproteobacteria	C	electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
TLS2_k127_1607482_2	614083.AWQR01000014_gene2458	4.762e-135	434.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2VHXJ@28216|Betaproteobacteria,4ABCD@80864|Comamonadaceae	28216|Betaproteobacteria	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
TLS2_k127_1607482_3	583345.Mmol_0085	6.737e-24	104.0	28XYV@1|root,2ZJUR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1607482_0	987059.RBXJA2T_03748	1.073e-197	622.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VH55@28216|Betaproteobacteria,1KJ43@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TLS2_k127_1611469_0	338969.Rfer_1713	1.51e-102	338.0	2DBW6@1|root,2ZBEP@2|Bacteria,1QZ6S@1224|Proteobacteria	1224|Proteobacteria	C	TIGRFAM decaheme c-type cytochrome, OmcA MtrC family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1611469_2	398767.Glov_3089	1.387e-10	68.0	COG1555@1|root,COG1555@2|Bacteria,1N7MI@1224|Proteobacteria	1224|Proteobacteria	L	Helix-hairpin-helix motif	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
TLS2_k127_1611469_1	1283300.ATXB01000002_gene2887	1.371e-54	206.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,1RZUI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
TLS2_k127_1614100_2	987059.RBXJA2T_14846	8.353e-66	231.0	COG0810@1|root,COG0810@2|Bacteria,1RJI3@1224|Proteobacteria,2WF00@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS2_k127_1614100_0	983917.RGE_14570	3.442e-137	448.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2VHEP@28216|Betaproteobacteria,1KJN5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
TLS2_k127_1614100_1	987059.RBXJA2T_14206	5.556e-74	255.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2VJ74@28216|Betaproteobacteria,1KK9W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K07552,ko:K18552	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.2,2.A.1.2.3	-	-	MFS_1
TLS2_k127_1622863_1	1379270.AUXF01000003_gene3535	1.368e-158	514.0	COG1007@1|root,COG1007@2|Bacteria,1ZUR0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TLS2_k127_1622863_0	379066.GAU_2391	3.582e-228	719.0	COG1008@1|root,COG1008@2|Bacteria,1ZUBB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TLS2_k127_1622863_2	765914.ThisiDRAFT_1054	3.732e-142	463.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1WWQ6@135613|Chromatiales	135613|Chromatiales	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
TLS2_k127_1628243_1	983917.RGE_21510	1.125e-125	424.0	COG0642@1|root,COG2199@1|root,COG2202@1|root,COG3852@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3852@2|Bacteria,1NRP8@1224|Proteobacteria,2VJNX@28216|Betaproteobacteria,1KJ6Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS_3,PAS_7,PAS_8,PAS_9,PilJ,Response_reg
TLS2_k127_1628243_2	983917.RGE_21520	4.072e-122	398.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2VKFT@28216|Betaproteobacteria,1KKZT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS2_k127_1628243_0	983917.RGE_21530	1.416e-135	444.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VRIK@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS2_k127_1634099_4	864051.BurJ1DRAFT_1592	6.302e-50	183.0	COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,2VIZ8@28216|Betaproteobacteria,1KJAI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
TLS2_k127_1634099_0	987059.RBXJA2T_14866	2.175e-151	496.0	COG0457@1|root,COG0457@2|Bacteria,1Q7UR@1224|Proteobacteria,2VKBS@28216|Betaproteobacteria,1KJ62@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
TLS2_k127_1634099_3	983917.RGE_34400	3.717e-62	219.0	COG0848@1|root,COG0848@2|Bacteria,1RHDF@1224|Proteobacteria,2VT16@28216|Betaproteobacteria,1KM2K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
TLS2_k127_1634099_2	983917.RGE_34390	4.118e-72	245.0	COG0848@1|root,COG0848@2|Bacteria,1RH4U@1224|Proteobacteria,2VSF4@28216|Betaproteobacteria,1KM48@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	exbD1	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
TLS2_k127_1634099_1	987059.RBXJA2T_14851	1.526e-117	381.0	COG0811@1|root,COG0811@2|Bacteria,1NMPB@1224|Proteobacteria,2VJ4U@28216|Betaproteobacteria,1KJUF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	exbB1	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
TLS2_k127_1636784_0	323848.Nmul_A2313	3.518e-97	325.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,371WH@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
TLS2_k127_1636784_1	1123368.AUIS01000005_gene383	3.656e-54	195.0	COG3255@1|root,COG3255@2|Bacteria,1N5G0@1224|Proteobacteria,1S8QU@1236|Gammaproteobacteria,2NCWZ@225057|Acidithiobacillales	225057|Acidithiobacillales	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
TLS2_k127_1636784_3	987059.RBXJA2T_17152	0.000176	44.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,1KJ2V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS2_k127_1636784_2	864051.BurJ1DRAFT_3321	2.366e-50	181.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,1KM2G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Bacterial regulatory proteins, luxR family	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
TLS2_k127_1644830_0	1500890.JQNL01000001_gene254	4.247e-155	505.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,1RS1U@1236|Gammaproteobacteria,1X7QU@135614|Xanthomonadales	135614|Xanthomonadales	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1644830_1	1304885.AUEY01000099_gene2595	7.174e-55	202.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42Q4P@68525|delta/epsilon subdivisions,2WJHQ@28221|Deltaproteobacteria,2MJRC@213118|Desulfobacterales	1224|Proteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585,ko:K07799,ko:K18901	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00646,M00647,M00648,M00698,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS2_k127_1648980_4	768671.ThimaDRAFT_4836	6.704e-45	170.0	COG4944@1|root,COG4944@2|Bacteria,1MXEV@1224|Proteobacteria,1S7DP@1236|Gammaproteobacteria,1WZDH@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1109
TLS2_k127_1648980_1	768671.ThimaDRAFT_4835	5.323e-61	216.0	COG1595@1|root,COG1595@2|Bacteria,1MVS7@1224|Proteobacteria,1S9FF@1236|Gammaproteobacteria,1WZCY@135613|Chromatiales	135613|Chromatiales	K	sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS2_k127_1648980_5	338969.Rfer_1598	4.905e-42	157.0	COG0526@1|root,COG0526@2|Bacteria,1MZQJ@1224|Proteobacteria,2VT2D@28216|Betaproteobacteria,4AHJA@80864|Comamonadaceae	28216|Betaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
TLS2_k127_1648980_0	365044.Pnap_2512	5.008e-126	406.0	COG0785@1|root,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2VIPU@28216|Betaproteobacteria	28216|Betaproteobacteria	O	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
TLS2_k127_1648980_3	395494.Galf_1894	1.917e-56	216.0	COG3258@1|root,COG3258@2|Bacteria,1NA2I@1224|Proteobacteria,2W47C@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
TLS2_k127_1656988_3	987059.RBXJA2T_02632	2.326e-25	105.0	COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria,2VR5U@28216|Betaproteobacteria,1KKW9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Cysteine-rich motif following a subset of SET domains	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
TLS2_k127_1656988_1	987059.RBXJA2T_02637	1.024e-112	372.0	COG0340@1|root,COG0340@2|Bacteria,1MWCC@1224|Proteobacteria,2VNXD@28216|Betaproteobacteria,1KKV9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
TLS2_k127_1656988_2	987059.RBXJA2T_02642	8.018e-50	185.0	2DD05@1|root,2ZG0C@2|Bacteria,1RC2B@1224|Proteobacteria,2VQ0R@28216|Betaproteobacteria,1KM8Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sporulation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1656988_0	395495.Lcho_1773	7.299e-153	506.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VIXC@28216|Betaproteobacteria,1KJ2I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Subtilase family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_3_2,Big_3_3,Peptidase_S8
TLS2_k127_1661249_2	987059.RBXJA2T_10444	3.371e-101	334.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,2VQRP@28216|Betaproteobacteria,1KKK0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
TLS2_k127_1661249_1	983917.RGE_31690	3.94e-107	353.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,2VJTJ@28216|Betaproteobacteria,1KK2C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the MtfA family	mtfA	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
TLS2_k127_1661249_0	987059.RBXJA2T_10434	3.362e-143	455.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria,1KK7T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
TLS2_k127_1671152_6	1454004.AW11_02849	3.866e-24	102.0	COG2212@1|root,COG2212@2|Bacteria,1N6VV@1224|Proteobacteria	1224|Proteobacteria	P	Multiple resistance and pH regulation protein F	mnhF	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
TLS2_k127_1671152_5	1454004.AW11_02850	6.205e-38	148.0	COG1320@1|root,COG1320@2|Bacteria	2|Bacteria	P	monovalent cation:proton antiporter activity	mnhG	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
TLS2_k127_1671152_3	1454004.AW11_02851	1.196e-61	223.0	COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria	1224|Proteobacteria	P	Na H antiporter, MnhB	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB
TLS2_k127_1671152_2	1454004.AW11_02852	1.714e-65	228.0	COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria	1224|Proteobacteria	P	Na H antiporter, MnhB	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB
TLS2_k127_1671152_4	1454004.AW11_02853	3.889e-40	159.0	COG1006@1|root,COG1006@2|Bacteria,1RGU1@1224|Proteobacteria	1224|Proteobacteria	P	COG1006 Multisubunit Na H antiporter, MnhC subunit	mnhC	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
TLS2_k127_1671152_0	1454004.AW11_02854	2.41e-215	683.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2VP1W@28216|Betaproteobacteria	28216|Betaproteobacteria	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
TLS2_k127_1671152_1	1454004.AW11_02855	1.901e-208	684.0	COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,2VPQP@28216|Betaproteobacteria	28216|Betaproteobacteria	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M,Proton_antipo_N
TLS2_k127_1671291_1	983917.RGE_39400	1.001e-73	252.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2VR41@28216|Betaproteobacteria,1KKXY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NT	Two component signalling adaptor domain	cheW-1	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
TLS2_k127_1671291_0	1265502.KB905929_gene2133	6.875e-243	758.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,4A9N1@80864|Comamonadaceae	28216|Betaproteobacteria	NT	Signal transducing histidine kinase, homodimeric	cheA	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,CheY-binding,H-kinase_dim,HATPase_c,Hpt
TLS2_k127_1671562_0	983917.RGE_21110	1.157e-153	493.0	COG3550@1|root,COG3550@2|Bacteria,1QJ5P@1224|Proteobacteria,2VNBA@28216|Betaproteobacteria,1KM3F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Pfam:HipA_N	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HipA_C
TLS2_k127_1671562_2	522306.CAP2UW1_3367	1.575e-48	200.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF,dCache_2
TLS2_k127_1671562_1	765911.Thivi_0413	4.188e-141	485.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WZVB@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
TLS2_k127_1674696_0	296591.Bpro_0920	1.348e-255	795.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,2VJ0R@28216|Betaproteobacteria,4AC30@80864|Comamonadaceae	28216|Betaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	hyfG	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
TLS2_k127_1674696_3	296591.Bpro_0921	1.326e-90	301.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2VP8A@28216|Betaproteobacteria,4AE12@80864|Comamonadaceae	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	hyfI	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
TLS2_k127_1674696_2	1286631.X805_38550	4.061e-162	518.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,2VHZZ@28216|Betaproteobacteria,1KIVE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
TLS2_k127_1674696_1	1286631.X805_38530	5.901e-223	700.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKJI@28216|Betaproteobacteria,1KJQW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS2_k127_1674696_4	1504672.669783922	1.593e-73	255.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,2VR4C@28216|Betaproteobacteria,4AE3U@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
TLS2_k127_1676384_0	1265502.KB905929_gene2208	1.701e-108	354.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2VJHE@28216|Betaproteobacteria,4ACC4@80864|Comamonadaceae	28216|Betaproteobacteria	S	N-terminal domain of oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
TLS2_k127_1682431_2	296591.Bpro_0898	1.047e-28	117.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2VH25@28216|Betaproteobacteria,4A9MY@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS2_k127_1682431_0	1005048.CFU_2991	1.503e-194	627.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2VK1F@28216|Betaproteobacteria,4742X@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
TLS2_k127_1682431_1	1144319.PMI16_04409	8.232e-96	346.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,2VPC3@28216|Betaproteobacteria	28216|Betaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
TLS2_k127_1685299_5	864051.BurJ1DRAFT_0039	5.487e-63	228.0	COG0526@1|root,COG0526@2|Bacteria,1MWU8@1224|Proteobacteria,2VPNK@28216|Betaproteobacteria,1KNFX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2,Thioredoxin_7
TLS2_k127_1685299_0	983917.RGE_00460	5.511e-251	813.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,2VPB3@28216|Betaproteobacteria,1KMYW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_4,TPR_6,TPR_8
TLS2_k127_1685299_10	864051.BurJ1DRAFT_3152	1.428e-13	81.0	2E400@1|root,32YWX@2|Bacteria,1N9MA@1224|Proteobacteria,2VWN4@28216|Betaproteobacteria,1KP3Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
TLS2_k127_1685299_7	983917.RGE_00430	5.937e-49	176.0	COG2343@1|root,COG2343@2|Bacteria,1N1K4@1224|Proteobacteria,2VU8K@28216|Betaproteobacteria,1KME9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
TLS2_k127_1685299_9	864051.BurJ1DRAFT_4482	2.606e-16	86.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHGK@28216|Betaproteobacteria,1KJH7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
TLS2_k127_1685299_2	1286631.X805_01660	2.329e-75	272.0	COG1653@1|root,COG1653@2|Bacteria,1R5TB@1224|Proteobacteria,2VXNU@28216|Betaproteobacteria,1KN77@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
TLS2_k127_1685299_6	420662.Mpe_A1010	5.841e-60	222.0	COG2839@1|root,COG2839@2|Bacteria,1MZEV@1224|Proteobacteria,2VSG8@28216|Betaproteobacteria,1KM6X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
TLS2_k127_1685299_3	420662.Mpe_A0055	2.42e-73	254.0	COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,2VQBI@28216|Betaproteobacteria,1KKYD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	NnrU protein	nnrU	-	-	-	-	-	-	-	-	-	-	-	NnrU
TLS2_k127_1685299_4	1158292.JPOE01000005_gene1018	4.099e-67	233.0	COG2030@1|root,COG2030@2|Bacteria,1RIBV@1224|Proteobacteria,2VTGX@28216|Betaproteobacteria,1KKWK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
TLS2_k127_1685299_1	983917.RGE_00320	7.35e-186	587.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2VJDV@28216|Betaproteobacteria,1KIYX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Required for the activity of the bacterial periplasmic transport system of putrescine	potF	-	-	ko:K11073	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	SBP_bac_8
TLS2_k127_1685299_8	1159870.KB907784_gene3095	1.015e-40	156.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2VIRU@28216|Betaproteobacteria,3T2J9@506|Alcaligenaceae	28216|Betaproteobacteria	E	ornithine cyclodeaminase	-	-	1.5.1.1,4.3.1.12	ko:K01750,ko:K19743	ko00310,ko00330,ko00960,ko01100,ko01110,ko01130,ko01230,map00310,map00330,map00960,map01100,map01110,map01130,map01230	-	R00671,R01246,R01249,R02201,R02203	RC00135,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
TLS2_k127_1690116_2	535289.Dtpsy_0043	7.16e-35	134.0	COG0727@1|root,32S46@2|Bacteria,1MZCU@1224|Proteobacteria,2VU00@28216|Betaproteobacteria,4AF7Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	Fe-S-cluster oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
TLS2_k127_1690116_1	987059.RBXJA2T_03978	3.877e-90	306.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,2VN3A@28216|Betaproteobacteria,1KKKS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	regulatory protein Crp	nnr	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS2_k127_1690116_3	987059.RBXJA2T_03973	3.226e-20	95.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2VVS2@28216|Betaproteobacteria,1KMJF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
TLS2_k127_1690116_0	330214.NIDE3498	6.772e-150	495.0	COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	fhlA	GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141	-	ko:K02584,ko:K12146,ko:K12266,ko:K15836,ko:K21009	ko02020,ko02025,ko05132,map02020,map02025,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,GAF_3,HTH_8,Sigma54_activat
TLS2_k127_1699408_3	987059.RBXJA2T_12382	4.844e-34	133.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,2VVQJ@28216|Betaproteobacteria,1KMJY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
TLS2_k127_1699408_0	987059.RBXJA2T_12377	4.778e-85	289.0	COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,2VRT2@28216|Betaproteobacteria,1KKZ4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Nicotinamide mononucleotide transporter	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
TLS2_k127_1699408_2	864051.BurJ1DRAFT_3713	7.457e-59	211.0	COG3172@1|root,COG3172@2|Bacteria,1RI98@1224|Proteobacteria,2VSFE@28216|Betaproteobacteria,1KM5K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
TLS2_k127_1699408_1	887898.HMPREF0551_2489	1.817e-63	233.0	COG4637@1|root,COG4637@2|Bacteria,1ND40@1224|Proteobacteria,2VHTI@28216|Betaproteobacteria,1K5IK@119060|Burkholderiaceae	28216|Betaproteobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
TLS2_k127_1699408_4	686340.Metal_1039	1.266e-30	128.0	2CAZG@1|root,2ZBT6@2|Bacteria,1RC91@1224|Proteobacteria,1SM1J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4276)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4276
TLS2_k127_1699408_5	987059.RBXJA2T_12367	5.864e-29	116.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2VI8B@28216|Betaproteobacteria,1KJ6G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
TLS2_k127_1712672_0	748247.AZKH_p0369	1.281e-72	254.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2VJHA@28216|Betaproteobacteria,2KWAS@206389|Rhodocyclales	28216|Betaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
TLS2_k127_1712672_1	748247.AZKH_p0370	7.947e-38	154.0	COG3218@1|root,COG3218@2|Bacteria,1NCG2@1224|Proteobacteria,2VWSK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
TLS2_k127_1715230_4	1049564.TevJSym_ay00150	3.91e-52	195.0	COG0642@1|root,COG3221@1|root,COG3437@1|root,COG5002@1|root,COG2205@2|Bacteria,COG3221@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1J8GC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	PAS fold	-	-	2.7.13.3	ko:K10715,ko:K20974	ko02020,ko02024,ko02025,map02020,map02024,map02025	M00517,M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE,DUF4118,GAF,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS2_k127_1715230_2	420662.Mpe_A1639	1.155e-56	201.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,2VSD1@28216|Betaproteobacteria,1KMHA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	MerR, DNA binding	cueR	-	-	ko:K19591,ko:K19592	-	M00768,M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
TLS2_k127_1715230_0	420662.Mpe_A1640	0.0	1021.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,1KJVH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
TLS2_k127_1715230_5	395495.Lcho_1834	2.806e-18	87.0	COG2608@1|root,COG2608@2|Bacteria,1PUDM@1224|Proteobacteria,2VX77@28216|Betaproteobacteria,1KMS1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
TLS2_k127_1715230_1	1249627.D779_3684	2.271e-133	455.0	COG0642@1|root,COG4191@1|root,COG0642@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1T1YU@1236|Gammaproteobacteria,1X2TQ@135613|Chromatiales	135613|Chromatiales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg
TLS2_k127_1715230_3	338969.Rfer_0414	1.597e-56	207.0	COG1651@1|root,COG1651@2|Bacteria,1MVS2@1224|Proteobacteria,2VQH7@28216|Betaproteobacteria,4AGU8@80864|Comamonadaceae	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
TLS2_k127_1727513_1	983917.RGE_46450	7.701e-126	412.0	COG3307@1|root,COG3307@2|Bacteria,1MYWJ@1224|Proteobacteria,2VKHZ@28216|Betaproteobacteria,1KJJW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Virulence factor membrane-bound polymerase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PglL_A,Wzy_C,Wzy_C_2
TLS2_k127_1727513_2	983917.RGE_46440	1.191e-77	261.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2VR7B@28216|Betaproteobacteria,1KKXV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
TLS2_k127_1727513_0	987059.RBXJA2T_13444	7.79e-130	426.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,1KKB2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Peptidase family M48	yggG_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
TLS2_k127_1729658_0	983917.RGE_10460	6.737e-236	749.0	COG3170@1|root,COG3170@2|Bacteria,1QV1N@1224|Proteobacteria,2WGRZ@28216|Betaproteobacteria,1KJQ0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
TLS2_k127_1729658_2	983917.RGE_10450	2.001e-145	469.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJN0@28216|Betaproteobacteria,1KJ36@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
TLS2_k127_1729658_1	983917.RGE_10430	1.128e-150	488.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,1KJA8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Trypsin	degQ	-	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
TLS2_k127_1733583_0	1454004.AW11_02857	1.683e-244	767.0	COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria	1224|Proteobacteria	CP	formate hydrogenlyase subunit 3 multisubunit Na H antiporter, MnhD subunit	nuoL3	-	-	ko:K05568,ko:K12137	-	-	-	-	ko00000,ko01000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
TLS2_k127_1733583_1	1454004.AW11_02856	2.41e-23	100.0	2EDYZ@1|root,337TS@2|Bacteria,1N7SA@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1739691_0	983917.RGE_41880	4.752e-96	323.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,1KPE4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Methyltransferase domain	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
TLS2_k127_1739691_2	987059.RBXJA2T_00115	3.765e-70	248.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,1KM58@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PFAM Phosphoribosyltransferase	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
TLS2_k127_1739691_1	864051.BurJ1DRAFT_4217	2.11e-72	256.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2VR5W@28216|Betaproteobacteria,1KKJI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
TLS2_k127_1739691_3	420662.Mpe_A0717	1.271e-44	165.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2VJ91@28216|Betaproteobacteria,1KJ5M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
TLS2_k127_1770784_0	1286631.X805_12150	6.631e-177	562.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VH78@28216|Betaproteobacteria,1KJY6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	molybdopterin	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
TLS2_k127_1770784_1	395495.Lcho_3723	2.636e-140	451.0	COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,2VK94@28216|Betaproteobacteria,1KJG6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
TLS2_k127_1772813_0	1276756.AUEX01000039_gene365	5.528e-136	434.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,4AAPK@80864|Comamonadaceae	28216|Betaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
TLS2_k127_1772813_3	338969.Rfer_3473	1.085e-25	110.0	COG3070@1|root,COG3070@2|Bacteria,1NEFA@1224|Proteobacteria,2VYN2@28216|Betaproteobacteria,4AG0B@80864|Comamonadaceae	28216|Betaproteobacteria	K	TfoX C-terminal domain	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_C
TLS2_k127_1772813_1	296591.Bpro_0072	2.801e-78	270.0	COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,2VTFR@28216|Betaproteobacteria,4ADH2@80864|Comamonadaceae	28216|Betaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
TLS2_k127_1772813_2	1538295.JY96_10995	2.185e-39	147.0	COG0727@1|root,32S46@2|Bacteria,1MZCU@1224|Proteobacteria,2VU00@28216|Betaproteobacteria,1KMDB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Fe-S-cluster oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
TLS2_k127_1774082_0	420662.Mpe_A2138	1.363e-142	464.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria,1KK3B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
TLS2_k127_1774082_4	768671.ThimaDRAFT_1903	1.593e-10	73.0	2E38E@1|root,32Y84@2|Bacteria,1N84V@1224|Proteobacteria,1SCI1@1236|Gammaproteobacteria,1WZ99@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1774082_3	545264.KB898751_gene2556	2.993e-31	127.0	COG1487@1|root,COG1487@2|Bacteria,1RJDP@1224|Proteobacteria,1SA6Q@1236|Gammaproteobacteria,1WZ0N@135613|Chromatiales	135613|Chromatiales	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
TLS2_k127_1774082_1	864051.BurJ1DRAFT_2305	9.273e-99	328.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2VH27@28216|Betaproteobacteria,1KJ1F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
TLS2_k127_1774082_2	987059.RBXJA2T_00440	1.939e-58	208.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,2VHGY@28216|Betaproteobacteria,1KJ1U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
TLS2_k127_1778749_1	983917.RGE_46010	4.897e-40	154.0	COG3087@1|root,COG3087@2|Bacteria,1RI6A@1224|Proteobacteria,2VR10@28216|Betaproteobacteria,1KKS6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Sporulation related domain	ftsN	-	-	-	-	-	-	-	-	-	-	-	SPOR
TLS2_k127_1778749_0	983917.RGE_46000	3.156e-292	905.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2VHT1@28216|Betaproteobacteria,1KJQ9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
TLS2_k127_1778749_2	987059.RBXJA2T_00729	1.155e-39	166.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria,1KJ5A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
TLS2_k127_1784172_0	983917.RGE_38470	1.383e-182	574.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VI3N@28216|Betaproteobacteria,1KJ13@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
TLS2_k127_1784172_1	983917.RGE_38450	6.62e-83	281.0	COG1708@1|root,COG1708@2|Bacteria,1NER6@1224|Proteobacteria,2W4UK@28216|Betaproteobacteria,1KNYF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1784172_2	983917.RGE_38440	4.076e-47	174.0	2ED4B@1|root,33712@2|Bacteria,1NDI5@1224|Proteobacteria,2W4K9@28216|Betaproteobacteria,1KNYA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1785786_3	1538295.JY96_13645	3.256e-11	63.0	COG4398@1|root,COG4398@2|Bacteria,1MUX9@1224|Proteobacteria,2VIY7@28216|Betaproteobacteria,1KJ2J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
TLS2_k127_1785786_2	338969.Rfer_3304	1.17e-34	139.0	2BX44@1|root,338XN@2|Bacteria,1N7KS@1224|Proteobacteria,2WFUJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1785786_0	987059.RBXJA2T_01180	0.0	1041.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VJFM@28216|Betaproteobacteria,1KJRB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
TLS2_k127_1785786_1	420662.Mpe_A1231	1.003e-57	203.0	COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,2W055@28216|Betaproteobacteria,1KNG4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1792032_1	987059.RBXJA2T_15423	4.795e-59	206.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,2VIJ1@28216|Betaproteobacteria,1KKIM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
TLS2_k127_1792032_2	338969.Rfer_2774	2.802e-52	188.0	COG2867@1|root,COG2867@2|Bacteria,1RI5E@1224|Proteobacteria	1224|Proteobacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS2_k127_1792032_0	365044.Pnap_3829	1.966e-258	805.0	COG0747@1|root,COG0747@2|Bacteria,1MWR7@1224|Proteobacteria,2VN67@28216|Betaproteobacteria,4AGQF@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
TLS2_k127_1805993_0	342113.DM82_5150	6.388e-219	689.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VKDB@28216|Betaproteobacteria,1K1JS@119060|Burkholderiaceae	28216|Betaproteobacteria	M	1-carboxyvinyltransferase	murA_1	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
TLS2_k127_1805993_4	395495.Lcho_2585	6.536e-78	265.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,2VQAY@28216|Betaproteobacteria,1KKM0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ebsC	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
TLS2_k127_1805993_1	640512.BC1003_5795	2.582e-183	588.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,1K1AF@119060|Burkholderiaceae	28216|Betaproteobacteria	T	histidine kinase HAMP region domain protein	aer	-	-	ko:K03406,ko:K03776,ko:K05874,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3,TarH,sCache_2
TLS2_k127_1805993_3	864051.BurJ1DRAFT_1994	8.669e-82	280.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2VQ10@28216|Betaproteobacteria,1KKN7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
TLS2_k127_1805993_5	983917.RGE_18590	3.176e-49	181.0	COG0251@1|root,COG0251@2|Bacteria,1MZ5K@1224|Proteobacteria,2VU19@28216|Betaproteobacteria,1KMA1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
TLS2_k127_1805993_2	420662.Mpe_A2757	1.05e-104	342.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VH4T@28216|Betaproteobacteria,1KKES@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
TLS2_k127_1805993_6	420662.Mpe_A1382	1.366e-42	156.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2VIP7@28216|Betaproteobacteria,1KIZQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
TLS2_k127_1809832_0	864051.BurJ1DRAFT_0190	5.513e-243	763.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2VINT@28216|Betaproteobacteria,1KJN8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
TLS2_k127_1817739_4	987059.RBXJA2T_08385	3.744e-10	61.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,1KIZX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
TLS2_k127_1817739_1	983917.RGE_23980	1.313e-103	349.0	COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,2VJI2@28216|Betaproteobacteria,1KJS8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EJ	Asparaginase	ansB	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
TLS2_k127_1817739_0	983917.RGE_23970	2.461e-114	372.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2VHTZ@28216|Betaproteobacteria,1KJT0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
TLS2_k127_1817739_3	983917.RGE_23960	4.278e-41	162.0	2CHW3@1|root,32S6N@2|Bacteria,1N0I3@1224|Proteobacteria,2VW65@28216|Betaproteobacteria,1KMGW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Pathogenicity locus	mcrB	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	Cdd1
TLS2_k127_1817739_2	1265502.KB905940_gene2956	7.101e-79	269.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2VIWI@28216|Betaproteobacteria,4AB5A@80864|Comamonadaceae	28216|Betaproteobacteria	S	peptidase S45, penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
TLS2_k127_1823139_1	296591.Bpro_2748	3.147e-69	241.0	COG0500@1|root,COG2226@2|Bacteria,1MZVH@1224|Proteobacteria,2VZ2M@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS2_k127_1823139_0	395495.Lcho_2487	7.102e-106	349.0	COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,2VHAG@28216|Betaproteobacteria,1KKI9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
TLS2_k127_184578_0	1265502.KB905936_gene2691	0.0	1159.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1MW2M@1224|Proteobacteria,2VK56@28216|Betaproteobacteria,4A9ZV@80864|Comamonadaceae	28216|Betaproteobacteria	CP	Na H antiporter MnhB subunit-related protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
TLS2_k127_184578_5	1000565.METUNv1_01243	2.09e-45	170.0	COG1006@1|root,COG1006@2|Bacteria,1RH8H@1224|Proteobacteria,2VSVU@28216|Betaproteobacteria,2KZ68@206389|Rhodocyclales	206389|Rhodocyclales	P	NADH-ubiquinone oxidoreductase chain 4L	-	-	-	ko:K05560	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	Oxidored_q2
TLS2_k127_184578_1	1265502.KB905936_gene2689	1.015e-202	644.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2VH1Y@28216|Betaproteobacteria,4AAUG@80864|Comamonadaceae	28216|Betaproteobacteria	CP	NADH Ubiquinone plastoquinone (Complex I)	mnhD	-	-	ko:K05561	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	Proton_antipo_M
TLS2_k127_184578_6	1265502.KB905936_gene2688	1.741e-44	168.0	COG1863@1|root,COG1863@2|Bacteria,1RH9F@1224|Proteobacteria,2VSM8@28216|Betaproteobacteria,4AE5S@80864|Comamonadaceae	28216|Betaproteobacteria	P	antiporter	phaE	-	-	ko:K05562	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	MNHE
TLS2_k127_184578_8	1265502.KB905936_gene2687	1.132e-25	118.0	COG2212@1|root,COG2212@2|Bacteria,1N8WJ@1224|Proteobacteria,2VWC1@28216|Betaproteobacteria,4AEZM@80864|Comamonadaceae	28216|Betaproteobacteria	P	Multiple resistance and pH regulation protein F	-	-	-	ko:K05563	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	MrpF_PhaF
TLS2_k127_184578_7	1265502.KB905936_gene2686	2.352e-37	144.0	COG1320@1|root,COG1320@2|Bacteria,1MZ6Z@1224|Proteobacteria,2VVWW@28216|Betaproteobacteria,4AFTX@80864|Comamonadaceae	28216|Betaproteobacteria	P	Na+/H+ antiporter subunit	mnhG	-	-	ko:K05564	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	PhaG_MnhG_YufB
TLS2_k127_184578_2	420662.Mpe_A1716	5.473e-139	451.0	COG0530@1|root,COG0530@2|Bacteria,1PW8G@1224|Proteobacteria,2VMK4@28216|Betaproteobacteria,1KKKP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
TLS2_k127_184578_4	1265502.KB905936_gene2684	7.351e-90	299.0	COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,2VK3P@28216|Betaproteobacteria,4A9XY@80864|Comamonadaceae	28216|Betaproteobacteria	S	UPF0114 protein	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
TLS2_k127_184578_3	1265502.KB905936_gene2683	1.103e-109	378.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria,4AARI@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
TLS2_k127_1847051_0	983917.RGE_27060	0.0	1159.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,1KJFB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS2_k127_1847051_2	983917.RGE_27040	2.285e-248	780.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria,1KK4K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
TLS2_k127_1847051_1	983917.RGE_27030	1.078e-309	971.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KJEE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CZB,Cache_3-Cache_2,EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS2_k127_1873352_1	864051.BurJ1DRAFT_2577	2.119e-144	469.0	COG0820@1|root,COG0820@2|Bacteria,1Q0HH@1224|Proteobacteria,2VMGJ@28216|Betaproteobacteria,1KJ7U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the radical SAM superfamily. RlmN family	rlmN_2	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
TLS2_k127_1873352_0	864051.BurJ1DRAFT_2059	8.116e-231	720.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,1KJKV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Ammonium Transporter	-	-	-	ko:K03320,ko:K06580	-	-	-	-	ko00000,ko02000,ko04090	1.A.11,1.A.11.4	-	-	Ammonium_transp
TLS2_k127_1873352_2	990285.RGCCGE502_07264	6.567e-20	94.0	COG2340@1|root,COG2340@2|Bacteria,1PGR3@1224|Proteobacteria,2V3Q6@28211|Alphaproteobacteria,4BKW3@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
TLS2_k127_1874730_3	1219031.BBJR01000084_gene858	3.583e-120	393.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2VK2D@28216|Betaproteobacteria,4AAKV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
TLS2_k127_1874730_4	1458427.BAWN01000009_gene589	1.625e-76	266.0	COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,2VQK6@28216|Betaproteobacteria,4AECH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
TLS2_k127_1874730_2	296591.Bpro_2524	1.365e-120	402.0	COG0824@1|root,COG2153@1|root,COG0824@2|Bacteria,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,2VMR6@28216|Betaproteobacteria,4A9NN@80864|Comamonadaceae	28216|Betaproteobacteria	S	Thioesterase superfamily protein	yjcF	-	-	-	-	-	-	-	-	-	-	-	4HBT,Acetyltransf_10
TLS2_k127_1874730_1	614083.AWQR01000037_gene3449	7.276e-139	450.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2VJSB@28216|Betaproteobacteria,4ACH0@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Alpha beta hydrolase fold-3 domain protein	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
TLS2_k127_1874730_0	296591.Bpro_2526	3.525e-169	537.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VI90@28216|Betaproteobacteria,4A9Y2@80864|Comamonadaceae	28216|Betaproteobacteria	C	alcohol dehydrogenase	gbd1	-	1.1.1.1,1.1.1.61	ko:K00043,ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01200,map01220	-	R00623,R00754,R01644,R04880,R05233,R05234,R06917,R06927	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
TLS2_k127_187609_0	983917.RGE_37700	0.0	1665.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria	28216|Betaproteobacteria	G	carbohydrate binding	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
TLS2_k127_1880235_2	395495.Lcho_0969	2.307e-60	224.0	COG0463@1|root,COG0463@2|Bacteria,1R3WX@1224|Proteobacteria,2VRNM@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Protein of unknown function (DUF4254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4254,Glycos_transf_2
TLS2_k127_1880235_1	395495.Lcho_0976	2.45e-87	308.0	COG0859@1|root,COG0859@2|Bacteria,1PMN2@1224|Proteobacteria,2VTS5@28216|Betaproteobacteria,1KMGB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	waaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
TLS2_k127_1880235_3	983917.RGE_13710	5.795e-27	113.0	COG1555@1|root,COG1555@2|Bacteria,1PU4R@1224|Proteobacteria,2WAPW@28216|Betaproteobacteria,1KMHW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
TLS2_k127_1880235_0	864051.BurJ1DRAFT_1766	2.129e-107	353.0	COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria,1KK15@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TLS2_k127_1884534_2	1349767.GJA_4660	3.745e-25	110.0	2E7Z7@1|root,332DJ@2|Bacteria,1N6VJ@1224|Proteobacteria,2VW3V@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1884534_0	338969.Rfer_3822	1.283e-213	674.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,4A9SZ@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	mucD	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
TLS2_k127_1884534_1	1123255.JHYS01000006_gene313	3.361e-31	124.0	COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,2W1JF@28216|Betaproteobacteria,4A9VC@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
TLS2_k127_1893899_3	1276756.AUEX01000026_gene253	7.564e-44	160.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria,4AJVP@80864|Comamonadaceae	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS2_k127_1893899_1	859657.RPSI07_mp1462	2.084e-133	438.0	COG4099@1|root,COG4099@2|Bacteria,1R7FZ@1224|Proteobacteria	1224|Proteobacteria	S	COG0790 FOG TPR repeat, SEL1 subfamily	VY92_08710	-	-	-	-	-	-	-	-	-	-	-	Esterase,Esterase_phd,Peptidase_S9
TLS2_k127_1893899_2	420662.Mpe_A3270	6.897e-80	271.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VRSR@28216|Betaproteobacteria,1KKZQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2238)	yjdF	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
TLS2_k127_1893899_0	864051.BurJ1DRAFT_4711	1.295e-181	571.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2VH4M@28216|Betaproteobacteria,1KJNU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
TLS2_k127_1899387_2	1123073.KB899241_gene3294	3.739e-75	254.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RSA2@1236|Gammaproteobacteria,1X3CK@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS2_k127_1899387_0	666685.R2APBS1_3323	8.09e-177	561.0	COG0577@1|root,COG0577@2|Bacteria,1MWBK@1224|Proteobacteria,1RPZF@1236|Gammaproteobacteria,1X3MX@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS2_k127_1899387_1	666685.R2APBS1_3322	1.671e-171	548.0	COG4591@1|root,COG4591@2|Bacteria,1QVRH@1224|Proteobacteria,1T2I0@1236|Gammaproteobacteria,1XD5X@135614|Xanthomonadales	135614|Xanthomonadales	M	COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS2_k127_1902657_0	395495.Lcho_3736	3.18e-249	783.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VP9Y@28216|Betaproteobacteria,1KKFK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Single cache domain 3	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
TLS2_k127_1902657_1	391735.Veis_1091	1.494e-101	336.0	COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,2VJ01@28216|Betaproteobacteria,4A9PC@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
TLS2_k127_1914322_0	864051.BurJ1DRAFT_0201	4.04e-193	616.0	COG1232@1|root,COG1232@2|Bacteria,1QX5M@1224|Proteobacteria,2WHD4@28216|Betaproteobacteria,1KK6Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
TLS2_k127_1914322_1	987059.RBXJA2T_02667	6.335e-79	265.0	COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria,2VMYU@28216|Betaproteobacteria,1KK3T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
TLS2_k127_1924393_2	420662.Mpe_A0316	2.125e-26	114.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,1KJ50@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
TLS2_k127_1924393_0	983917.RGE_44070	8.782e-98	325.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria,1KK26@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
TLS2_k127_1924393_1	983917.RGE_45480	1.05e-91	304.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2W06E@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
TLS2_k127_1949041_2	420662.Mpe_A2488	2.3e-89	296.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2VH1C@28216|Betaproteobacteria,1KJWW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
TLS2_k127_1949041_0	987059.RBXJA2T_10324	7.761e-111	363.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2VINM@28216|Betaproteobacteria,1KJA1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
TLS2_k127_1949041_4	864051.BurJ1DRAFT_3512	7.56e-26	108.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2VW58@28216|Betaproteobacteria,1KMR9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0434 family	ycaR	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
TLS2_k127_1949041_1	987059.RBXJA2T_10334	1.31e-104	353.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,1KJ4E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
TLS2_k127_1949041_3	987059.RBXJA2T_10339	3.686e-58	207.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,2VUF4@28216|Betaproteobacteria,1KM7P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Biopolymer transport protein ExbD TolR	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
TLS2_k127_1949041_5	987059.RBXJA2T_10344	2.504e-22	96.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,2VITY@28216|Betaproteobacteria,1KJMS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	exbB2	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
TLS2_k127_1968777_5	420662.Mpe_A2206	1.465e-23	104.0	COG2388@1|root,COG2388@2|Bacteria,1N8AQ@1224|Proteobacteria,2VW02@28216|Betaproteobacteria,1KMIR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
TLS2_k127_1968777_0	983917.RGE_45880	1.536e-303	964.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,1KNF8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_8,PAS_9,Response_reg
TLS2_k127_1968777_3	420662.Mpe_A3625	2.295e-122	421.0	COG0284@1|root,COG0284@2|Bacteria,1MWH5@1224|Proteobacteria,2VHAB@28216|Betaproteobacteria,1KKBC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
TLS2_k127_1968777_1	864051.BurJ1DRAFT_1733	3.268e-235	735.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2VI2T@28216|Betaproteobacteria,1KJIE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
TLS2_k127_1968777_2	296591.Bpro_1509	2.855e-226	709.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VHC1@28216|Betaproteobacteria,4AJ6S@80864|Comamonadaceae	28216|Betaproteobacteria	C	Resistance to Hg(2 ) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0)	-	-	1.16.1.1	ko:K00520,ko:K21739	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS2_k127_1968777_4	987059.RBXJA2T_04643	1.543e-73	260.0	COG1566@1|root,COG1566@2|Bacteria,1R50C@1224|Proteobacteria,2W4WI@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
TLS2_k127_1982010_1	1121124.JNIX01000006_gene1129	9.221e-43	162.0	COG3387@1|root,COG3387@2|Bacteria,1MW9J@1224|Proteobacteria,2TWPA@28211|Alphaproteobacteria,2KIA9@204458|Caulobacterales	204458|Caulobacterales	G	PFAM coagulation factor 5 8 type domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_11,F5_F8_type_C
TLS2_k127_1982010_0	243233.MCA1586	7.127e-225	719.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,1XDIT@135618|Methylococcales	135618|Methylococcales	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
TLS2_k127_1993476_0	1265502.KB905946_gene1147	9.166e-186	590.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,2VJ45@28216|Betaproteobacteria,4AAG9@80864|Comamonadaceae	28216|Betaproteobacteria	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
TLS2_k127_1993476_1	983917.RGE_11820	1.705e-175	580.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2VH5M@28216|Betaproteobacteria,1KJ6I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
TLS2_k127_1999943_5	983917.RGE_41480	1.553e-25	110.0	COG4636@1|root,COG4636@2|Bacteria,1RDIC@1224|Proteobacteria,2VS19@28216|Betaproteobacteria,1KNPP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
TLS2_k127_1999943_0	987059.RBXJA2T_06675	1.116e-202	638.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,1KJ04@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	bplF	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TLS2_k127_1999943_4	1454004.AW11_03741	1.766e-48	177.0	COG1848@1|root,COG1848@2|Bacteria,1MZR2@1224|Proteobacteria,2VUKP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
TLS2_k127_1999943_6	1454004.AW11_03740	1.879e-17	85.0	2DP6R@1|root,330SH@2|Bacteria,1N9YN@1224|Proteobacteria,2VYTQ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_1999943_3	864051.BurJ1DRAFT_4141	4.421e-85	291.0	COG0500@1|root,COG0500@2|Bacteria,1RBAM@1224|Proteobacteria,2VQHX@28216|Betaproteobacteria,1KKPG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
TLS2_k127_1999943_1	358220.C380_07315	4.168e-194	613.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,2VK2I@28216|Betaproteobacteria,4ADFC@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyl transferase 4-like domain	wlbE	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS2_k127_1999943_2	358220.C380_07320	5.558e-158	506.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,2WFJ1@28216|Betaproteobacteria,4AJSS@80864|Comamonadaceae	28216|Betaproteobacteria	G	UDP-N-acetylglucosamine 2-epimerase	wlbD	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
TLS2_k127_1999943_7	1095769.CAHF01000023_gene561	7.736e-08	54.0	COG0438@1|root,COG0438@2|Bacteria,1MWU0@1224|Proteobacteria,2VNNX@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS2_k127_2015500_1	983917.RGE_27500	7.214e-180	577.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VI86@28216|Betaproteobacteria,1KJBX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
TLS2_k127_2015500_3	420662.Mpe_A1991	3.958e-43	158.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2VTXK@28216|Betaproteobacteria,1KM9R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
TLS2_k127_2015500_0	983917.RGE_27520	4.116e-239	754.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2VI8D@28216|Betaproteobacteria,1KJJ0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
TLS2_k127_2015500_2	983917.RGE_27530	1.582e-74	254.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria,1KK5S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
TLS2_k127_2015633_1	296591.Bpro_2034	1.133e-54	203.0	COG1309@1|root,COG1309@2|Bacteria,1N659@1224|Proteobacteria,2VS47@28216|Betaproteobacteria,4AE9P@80864|Comamonadaceae	28216|Betaproteobacteria	K	Tetracycline transcriptional repressor MAATS-type	acrR	-	-	ko:K03577	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_2,TetR_N
TLS2_k127_2015633_0	1265502.KB905947_gene1095	6.298e-109	360.0	COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,2VKTC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
TLS2_k127_2015633_2	1538295.JY96_08420	1.752e-32	131.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2VIAZ@28216|Betaproteobacteria,1KPJ3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Glycosyltransferase family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
TLS2_k127_2023269_1	987059.RBXJA2T_08525	1.544e-92	308.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2VQ24@28216|Betaproteobacteria,1KKNX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
TLS2_k127_2023269_0	420662.Mpe_A1861	7.781e-123	399.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2VHD4@28216|Betaproteobacteria,1KJYW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
TLS2_k127_2034508_1	983917.RGE_21560	5.211e-72	248.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,1KJN6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
TLS2_k127_2034508_0	864051.BurJ1DRAFT_1760	1.084e-203	640.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,1KIT6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
TLS2_k127_2037136_2	420662.Mpe_A1322	8.153e-118	399.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,2VHXY@28216|Betaproteobacteria,1KNC7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
TLS2_k127_2037136_5	1157708.KB907450_gene5678	1.25e-49	187.0	COG2834@1|root,COG2834@2|Bacteria,1RHYN@1224|Proteobacteria,2VSXY@28216|Betaproteobacteria,4AEIN@80864|Comamonadaceae	28216|Betaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA
TLS2_k127_2037136_3	420662.Mpe_A1320	2.677e-114	379.0	COG4261@1|root,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,2VHP0@28216|Betaproteobacteria,1KNCT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
TLS2_k127_2037136_0	543728.Vapar_2671	7.274e-192	615.0	COG0318@1|root,COG0764@1|root,COG0318@2|Bacteria,COG0764@2|Bacteria,1MXPB@1224|Proteobacteria,2VJ3A@28216|Betaproteobacteria,4ABEX@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,FabA
TLS2_k127_2037136_6	420662.Mpe_A1317	2.199e-43	165.0	COG4648@1|root,COG4648@2|Bacteria,1RII0@1224|Proteobacteria,2VSMC@28216|Betaproteobacteria,1KP6F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2037136_8	420662.Mpe_A1316	3.538e-29	121.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,2VWKA@28216|Betaproteobacteria,1KNY8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TLS2_k127_2037136_4	983917.RGE_38610	1.597e-55	199.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSKZ@28216|Betaproteobacteria,1KM38@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	FKBP-type peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
TLS2_k127_2037136_1	987059.RBXJA2T_10861	2.039e-152	487.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria,1KJTH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
TLS2_k127_2039486_1	1502850.FG91_02607	3.7e-201	642.0	28NSE@1|root,2ZBRD@2|Bacteria,1N5JE@1224|Proteobacteria,2UUFU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2039486_2	1502850.FG91_02606	1.398e-139	449.0	COG1131@1|root,COG1131@2|Bacteria,1R3XF@1224|Proteobacteria,2UQ9F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS2_k127_2039486_4	1502850.FG91_02605	2.219e-49	179.0	COG1725@1|root,COG1725@2|Bacteria,1N163@1224|Proteobacteria,2UUIZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
TLS2_k127_2039486_0	395495.Lcho_0912	6.507e-267	825.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,1KJ2B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 2 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
TLS2_k127_2039486_3	864051.BurJ1DRAFT_3781	1.02e-57	206.0	COG4446@1|root,COG4446@2|Bacteria,1N7IZ@1224|Proteobacteria,2VSQW@28216|Betaproteobacteria,1KNPX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
TLS2_k127_2047992_2	987059.RBXJA2T_17534	3.024e-60	209.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2VJNS@28216|Betaproteobacteria,1KJXY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904	2.7.7.7	ko:K02346,ko:K03502	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
TLS2_k127_2047992_0	1123504.JQKD01000002_gene3682	6.378e-220	687.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2VH77@28216|Betaproteobacteria,4AAT7@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FMN-dependent alpha-hydroxy acid dehydrogenase	lldD	-	1.1.2.3,1.1.3.15	ko:K00101,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00196,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
TLS2_k127_2047992_1	1538295.JY96_02800	2.361e-75	258.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,1KJAN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
TLS2_k127_2072882_2	864051.BurJ1DRAFT_3343	1.112e-29	134.0	COG1974@1|root,COG1974@2|Bacteria,1QUQ8@1224|Proteobacteria,2VWS0@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
TLS2_k127_2072882_0	864051.BurJ1DRAFT_3342	7.098e-197	635.0	COG1018@1|root,COG1018@2|Bacteria,1REP4@1224|Proteobacteria,2VPWB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2
TLS2_k127_2072882_1	864051.BurJ1DRAFT_3341	1.92e-100	336.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,2VIG6@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
TLS2_k127_2095154_11	1408419.JHYG01000001_gene1981	1.378e-07	54.0	COG4731@1|root,COG4731@2|Bacteria,1N7E7@1224|Proteobacteria,2UHSI@28211|Alphaproteobacteria,2JXGY@204441|Rhodospirillales	204441|Rhodospirillales	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
TLS2_k127_2095154_7	983917.RGE_31860	1.014e-69	254.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2VH04@28216|Betaproteobacteria,1KJZH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS2_k127_2095154_10	929712.KI912613_gene4258	9.31e-20	102.0	COG2066@1|root,COG2905@1|root,COG2066@2|Bacteria,COG2905@2|Bacteria,2GKAV@201174|Actinobacteria,4CRGA@84995|Rubrobacteria	84995|Rubrobacteria	ET	Glutaminase	-	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase,cNMP_binding
TLS2_k127_2095154_5	1396418.BATQ01000127_gene2553	1.553e-118	411.0	COG0659@1|root,COG2066@1|root,COG0659@2|Bacteria,COG2066@2|Bacteria,46USD@74201|Verrucomicrobia,2ITM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	ET	Glutaminase	-	-	-	-	-	-	-	-	-	-	-	-	Glutaminase,cNMP_binding
TLS2_k127_2095154_6	864051.BurJ1DRAFT_1696	2.072e-75	256.0	COG3313@1|root,COG3313@2|Bacteria,1N711@1224|Proteobacteria,2VW2B@28216|Betaproteobacteria,1KKUM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3717)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289,DUF3717
TLS2_k127_2095154_2	983917.RGE_35160	9.177e-178	582.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2VH2B@28216|Betaproteobacteria,1KJU2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	MatE	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
TLS2_k127_2095154_1	987059.RBXJA2T_18413	2.277e-182	582.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1N9SU@1224|Proteobacteria,2VI30@28216|Betaproteobacteria,1KIV1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS2_k127_2095154_4	987059.RBXJA2T_18418	2.913e-127	409.0	COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,2VM6W@28216|Betaproteobacteria,1KJE7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	PFAM response regulator receiver	ompR2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS2_k127_2095154_9	420662.Mpe_A2644	1.267e-32	135.0	COG3678@1|root,COG3678@2|Bacteria,1NBYM@1224|Proteobacteria,2VXG9@28216|Betaproteobacteria,1KMIK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
TLS2_k127_2095154_0	864051.BurJ1DRAFT_1680	1.18e-227	710.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2VHJJ@28216|Betaproteobacteria,1KKEE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
TLS2_k127_2095154_3	983917.RGE_35320	3.827e-169	535.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria,1KIYE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
TLS2_k127_2095154_8	1265502.KB905941_gene2929	1.269e-61	217.0	COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,2VRJ4@28216|Betaproteobacteria,4ADNQ@80864|Comamonadaceae	28216|Betaproteobacteria	G	Peptidyl-prolyl cis-trans isomerase	fkpB	-	5.2.1.8	ko:K03774	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
TLS2_k127_2100492_2	987059.RBXJA2T_02582	6.071e-64	223.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria,1KM6N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
TLS2_k127_2100492_0	983917.RGE_44620	0.0	1013.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria,1KJ1E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	ntrY	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_7,PAS_8
TLS2_k127_2100492_1	983917.RGE_44610	2.369e-104	345.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VKD8@28216|Betaproteobacteria,1KJ37@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	response regulator	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
TLS2_k127_2100492_3	1121121.KB894333_gene4598	3.635e-06	50.0	2ED1A@1|root,336Y8@2|Bacteria,1VNP3@1239|Firmicutes,4HRCX@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2113587_0	983917.RGE_03210	0.0	1445.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2VIF3@28216|Betaproteobacteria,1KJ6A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
TLS2_k127_2113587_1	1286631.X805_04580	9.984e-29	123.0	COG1569@1|root,COG1569@2|Bacteria,1NASM@1224|Proteobacteria,2VVUB@28216|Betaproteobacteria,1KMJW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
TLS2_k127_2113587_2	1538295.JY96_12675	5.436e-12	67.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,2VR2H@28216|Betaproteobacteria,1KKJZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
TLS2_k127_2113854_0	365044.Pnap_4039	1.516e-189	602.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKRZ@28216|Betaproteobacteria,4AAEX@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
TLS2_k127_2113854_1	1268622.AVS7_02110	2.595e-124	407.0	COG0583@1|root,COG0583@2|Bacteria,1QYAP@1224|Proteobacteria,2VHXD@28216|Betaproteobacteria,4ABRM@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	ko:K21699	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
TLS2_k127_2113854_2	358220.C380_00505	1.933e-87	297.0	28MAA@1|root,2ZAP0@2|Bacteria,1R5EZ@1224|Proteobacteria,2VNTE@28216|Betaproteobacteria,4AHBF@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2115031_3	62928.azo3266	5.856e-45	167.0	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,2VIWN@28216|Betaproteobacteria,2KVT6@206389|Rhodocyclales	206389|Rhodocyclales	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
TLS2_k127_2115031_1	1454004.AW11_02196	2.728e-145	476.0	COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,2VKT7@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Wzy family polymerase, exosortase system type 1 associated	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
TLS2_k127_2115031_0	983917.RGE_04230	4.246e-203	641.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VMX6@28216|Betaproteobacteria,1KPM0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	AMP-binding enzyme	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
TLS2_k127_2115031_2	1454004.AW11_02195	6.196e-106	346.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
TLS2_k127_2116764_2	987059.RBXJA2T_18568	1.089e-69	236.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2VHMW@28216|Betaproteobacteria,1KJQ3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KLT	Serine threonine protein kinase	spkD	-	-	-	-	-	-	-	-	-	-	-	Pkinase
TLS2_k127_2116764_0	864051.BurJ1DRAFT_1664	2.09e-155	496.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,1KIYH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	phosphatase	pphA	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
TLS2_k127_2116764_1	987059.RBXJA2T_18558	3.314e-120	392.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2VIGI@28216|Betaproteobacteria,1KJ3P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
TLS2_k127_2116764_3	1121035.AUCH01000003_gene1314	8.969e-16	87.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2VQ1Z@28216|Betaproteobacteria,2KVRN@206389|Rhodocyclales	206389|Rhodocyclales	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
TLS2_k127_2138853_1	382245.ASA_2108	3.324e-52	199.0	COG3829@1|root,COG3829@2|Bacteria,1QW3X@1224|Proteobacteria,1SJT6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4,PAS_9
TLS2_k127_2138853_0	1255043.TVNIR_2417	6.878e-153	493.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1WWBN@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD_5,Response_reg
TLS2_k127_2164136_2	987059.RBXJA2T_05138	2.763e-75	253.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2VQBV@28216|Betaproteobacteria,1KKMB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix ASNC type	lrp	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
TLS2_k127_2164136_1	864051.BurJ1DRAFT_0086	6.269e-96	320.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,1KJYP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
TLS2_k127_2164136_0	987059.RBXJA2T_05123	1.122e-197	621.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,1KJTZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669,ko:K12203	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2,3.A.7.10.1,3.A.7.9.1	-	-	T2SSE
TLS2_k127_2176893_0	864051.BurJ1DRAFT_3661	4.369e-207	646.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,1KJ0W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
TLS2_k127_2176893_1	296591.Bpro_2804	7.232e-97	325.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2VIMM@28216|Betaproteobacteria,4AB8V@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit	fdwB	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
TLS2_k127_2179357_3	864051.BurJ1DRAFT_4431	5.49e-21	98.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2VIYT@28216|Betaproteobacteria,1KJKM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
TLS2_k127_2179357_1	983917.RGE_09450	1.216e-59	209.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2VRGP@28216|Betaproteobacteria,1KKYX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
TLS2_k127_2179357_0	338969.Rfer_3389	1.399e-91	304.0	COG2128@1|root,COG2128@2|Bacteria,1RBG0@1224|Proteobacteria,2VKY2@28216|Betaproteobacteria,4ADT5@80864|Comamonadaceae	28216|Betaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
TLS2_k127_2179357_2	75379.Tint_0808	7.331e-29	121.0	COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,1NWNJ@1224|Proteobacteria,2W2SI@28216|Betaproteobacteria,1KPEV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4
TLS2_k127_2182452_1	1454004.AW11_00067	7.295e-133	430.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
TLS2_k127_2182452_2	522306.CAP2UW1_4288	3.085e-104	351.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJBY@28216|Betaproteobacteria	28216|Betaproteobacteria	V	abc transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS2_k127_2182452_0	522306.CAP2UW1_4287	1.752e-167	537.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VIIH@28216|Betaproteobacteria	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS2_k127_2182452_3	1163617.SCD_n00411	2.067e-40	168.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VKXU@28216|Betaproteobacteria	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS2_k127_2185286_0	535289.Dtpsy_2859	5.015e-104	338.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VHGU@28216|Betaproteobacteria,4AAW8@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
TLS2_k127_2185286_1	1265502.KB905941_gene2883	1.593e-82	289.0	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,2VHRQ@28216|Betaproteobacteria,4AADH@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM Cytochrome c oxidase assembly protein CtaG Cox11	ctaG	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
TLS2_k127_2185286_3	1538295.JY96_05390	9.851e-19	94.0	2CDU3@1|root,33AS4@2|Bacteria,1NGWQ@1224|Proteobacteria,2VXNC@28216|Betaproteobacteria,1KMJR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2970)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2970
TLS2_k127_2185286_2	420662.Mpe_A3177	1.81e-39	150.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VJAP@28216|Betaproteobacteria,1KJDY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c oxidase subunit	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
TLS2_k127_222342_4	1100721.ALKO01000017_gene1670	4.713e-87	288.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,4ACN6@80864|Comamonadaceae	28216|Betaproteobacteria	G	carbohydrate phosphatase activity	fbp1	-	3.1.3.11,3.1.3.37	ko:K01086	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R01845,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase
TLS2_k127_222342_2	365044.Pnap_1983	8.634e-170	536.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,2VHZD@28216|Betaproteobacteria,4ACB0@80864|Comamonadaceae	28216|Betaproteobacteria	C	Phosphoribulokinase / Uridine kinase family	cbbP	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
TLS2_k127_222342_0	266264.Rmet_1513	3.25e-293	916.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,1KCWD@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
TLS2_k127_222342_6	420662.Mpe_A1484	3.171e-74	256.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VHJ3@28216|Betaproteobacteria,1KKV5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Mannitol_dh_C
TLS2_k127_222342_5	29581.BW37_02804	1.819e-75	258.0	COG0386@1|root,COG0386@2|Bacteria,1RDR8@1224|Proteobacteria,2VQHV@28216|Betaproteobacteria,4747T@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Glutathione peroxidase	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
TLS2_k127_222342_3	864051.BurJ1DRAFT_1179	3.984e-164	524.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria,1KMCB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
TLS2_k127_222342_7	864051.BurJ1DRAFT_1189	4.2e-35	136.0	COG4281@1|root,COG4281@2|Bacteria,1MZPP@1224|Proteobacteria,2VUK0@28216|Betaproteobacteria,1KM9E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	acyl-coA-binding protein	acb	-	-	-	-	-	-	-	-	-	-	-	ACBP
TLS2_k127_222342_1	983917.RGE_08500	4.375e-180	571.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,2VIJ1@28216|Betaproteobacteria,1KKIM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
TLS2_k127_2235977_0	983917.RGE_46450	3.113e-133	435.0	COG3307@1|root,COG3307@2|Bacteria,1MYWJ@1224|Proteobacteria,2VKHZ@28216|Betaproteobacteria,1KJJW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Virulence factor membrane-bound polymerase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PglL_A,Wzy_C,Wzy_C_2
TLS2_k127_2235977_1	243365.CV_4208	3.893e-10	72.0	COG3307@1|root,COG3307@2|Bacteria,1MYWJ@1224|Proteobacteria,2VKZA@28216|Betaproteobacteria,2KSN1@206351|Neisseriales	206351|Neisseriales	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PglL_A,Wzy_C,Wzy_C_2
TLS2_k127_2239176_5	1538295.JY96_11070	3.591e-69	239.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2VHCJ@28216|Betaproteobacteria,1KJW2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
TLS2_k127_2239176_0	983917.RGE_46990	1.93e-321	996.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria,1KJA0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
TLS2_k127_2239176_1	987059.RBXJA2T_07533	1.825e-140	452.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria,1KJ44@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
TLS2_k127_2239176_3	987059.RBXJA2T_07538	3.516e-80	271.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,2VRQX@28216|Betaproteobacteria,1KKN6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
TLS2_k127_2239176_4	987059.RBXJA2T_07543	4.043e-73	255.0	COG3117@1|root,COG3117@2|Bacteria,1R5UK@1224|Proteobacteria,2VU37@28216|Betaproteobacteria,1KM9G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Lipopolysaccharide-assembly, LptC-related	lptC	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
TLS2_k127_2239176_2	983917.RGE_46950	6.312e-112	370.0	COG0300@1|root,COG0300@2|Bacteria,1PNDU@1224|Proteobacteria,2VIWD@28216|Betaproteobacteria,1KJX2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	wcbP	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS2_k127_2247874_4	987059.RBXJA2T_19166	3.604e-47	173.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria,1KJUT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Flavin containing amine oxidoreductase	hpnE	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
TLS2_k127_2247874_1	864051.BurJ1DRAFT_2999	2.744e-134	439.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2VHB6@28216|Betaproteobacteria,1KIV2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulator	yiaJ	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
TLS2_k127_2247874_2	983917.RGE_28020	1.308e-119	394.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,1KJDZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	pbpG	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
TLS2_k127_2247874_0	1265502.KB905935_gene3128	2.1e-288	890.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VI4G@28216|Betaproteobacteria,4AAW6@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
TLS2_k127_2247874_3	987059.RBXJA2T_19186	3.425e-52	186.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2VIME@28216|Betaproteobacteria,1KJ76@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
TLS2_k127_225400_1	926569.ANT_12440	5.476e-93	309.0	COG0137@1|root,COG0137@2|Bacteria,2G5ME@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the argininosuccinate synthase family. Type	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
TLS2_k127_225400_0	383372.Rcas_3075	9.334e-151	489.0	COG0165@1|root,COG0165@2|Bacteria,2G616@200795|Chloroflexi,375AG@32061|Chloroflexia	32061|Chloroflexia	E	PFAM fumarate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
TLS2_k127_225400_5	1122604.JONR01000033_gene8	4.944e-38	149.0	COG4319@1|root,COG4319@2|Bacteria,1N361@1224|Proteobacteria,1S9P8@1236|Gammaproteobacteria,1X7TS@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2,SnoaL_3
TLS2_k127_225400_4	535289.Dtpsy_3452	2.059e-62	232.0	COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,2VR0I@28216|Betaproteobacteria,4AFQ2@80864|Comamonadaceae	28216|Betaproteobacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_225400_3	1265502.KB905972_gene1341	2.837e-83	286.0	COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,2VR7D@28216|Betaproteobacteria,4AJE8@80864|Comamonadaceae	28216|Betaproteobacteria	D	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_225400_2	535289.Dtpsy_3452	8.764e-86	295.0	COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,2VR0I@28216|Betaproteobacteria,4AFQ2@80864|Comamonadaceae	28216|Betaproteobacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2259680_4	84531.JMTZ01000014_gene2802	1.23e-78	281.0	2E2H1@1|root,32XM1@2|Bacteria,1RIZ2@1224|Proteobacteria,1SBDP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2259680_0	84531.JMTZ01000014_gene2801	0.0	1087.0	2DBKT@1|root,2Z9V9@2|Bacteria,1QVR5@1224|Proteobacteria,1T2HN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2259680_1	84531.JMTZ01000014_gene2800	1.2e-158	510.0	2C3RM@1|root,2Z9H1@2|Bacteria,1RFBU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2259680_2	84531.JMTZ01000014_gene2800	3.675e-142	459.0	2C3RM@1|root,2Z9H1@2|Bacteria,1RFBU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2259680_5	84531.JMTZ01000014_gene2799	4.164e-22	107.0	2EUJ2@1|root,33N13@2|Bacteria,1P7JM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2259680_3	84531.JMTZ01000014_gene2798	5.063e-88	300.0	2EK9G@1|root,33DZS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2268083_2	338969.Rfer_0413	5.558e-95	321.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,2VMAB@28216|Betaproteobacteria,4AD40@80864|Comamonadaceae	28216|Betaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS2_k127_2268083_1	1304883.KI912532_gene2831	6.183e-201	654.0	COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,2KVT7@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23
TLS2_k127_2268083_0	159087.Daro_2265	0.0	1753.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KUGU@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
TLS2_k127_2268083_3	864051.BurJ1DRAFT_2402	5.444e-85	285.0	COG1225@1|root,COG1225@2|Bacteria,1RA5K@1224|Proteobacteria,2VP6C@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
TLS2_k127_2268083_4	1454004.AW11_02848	3.816e-55	198.0	COG1863@1|root,COG1863@2|Bacteria,1MZYJ@1224|Proteobacteria	1224|Proteobacteria	P	COG1863 Multisubunit Na H antiporter MnhE subunit	mnhE	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
TLS2_k127_2296200_1	983917.RGE_10140	8.442e-84	286.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2VQ3U@28216|Betaproteobacteria,1KKN3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
TLS2_k127_2296200_0	983917.RGE_10190	4.125e-148	476.0	COG4589@1|root,COG4589@2|Bacteria,1MX58@1224|Proteobacteria,2VH1P@28216|Betaproteobacteria,1KKB5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
TLS2_k127_2296200_2	987059.RBXJA2T_06830	2.803e-64	221.0	COG0204@1|root,COG0204@2|Bacteria,1RA8V@1224|Proteobacteria,2VQ8G@28216|Betaproteobacteria,1KJA5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TLS2_k127_2305826_0	1458275.AZ34_02040	3.509e-181	575.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VIPR@28216|Betaproteobacteria,4AA3P@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Cyclopropane-fatty-acyl-phospholipid synthase	cfa2	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
TLS2_k127_2305826_3	614083.AWQR01000054_gene1946	6.504e-06	51.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,2VHZ1@28216|Betaproteobacteria,4AAFQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	hydrolase of the alpha	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
TLS2_k127_2305826_1	358220.C380_21465	2.379e-115	376.0	COG2872@1|root,COG2872@2|Bacteria,1MY0P@1224|Proteobacteria,2VMEB@28216|Betaproteobacteria,4ABNF@80864|Comamonadaceae	28216|Betaproteobacteria	S	Threonyl alanyl tRNA synthetase SAD	alaS_2	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
TLS2_k127_2305826_2	338969.Rfer_3746	4.815e-100	346.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,2VK37@28216|Betaproteobacteria,4AAFN@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
TLS2_k127_2332805_3	395493.BegalDRAFT_1049	3.449e-07	61.0	2FFX0@1|root,347TX@2|Bacteria,1NZX4@1224|Proteobacteria,1SR5F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	T2SSM_b
TLS2_k127_2332805_1	395493.BegalDRAFT_2655	8.259e-15	86.0	2DRBX@1|root,33B5J@2|Bacteria,1NK8Z@1224|Proteobacteria,1SI1J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2332805_0	322710.Avin_16110	2.93e-15	89.0	COG3156@1|root,COG3156@2|Bacteria,1N46V@1224|Proteobacteria,1SA83@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	type II secretion system protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
TLS2_k127_2332805_2	395493.BegalDRAFT_2142	4.833e-08	63.0	COG2165@1|root,COG2165@2|Bacteria,1NKMW@1224|Proteobacteria,1SHQI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TLS2_k127_2334059_4	29581.BW37_00065	1.085e-40	158.0	COG4772@1|root,COG4772@2|Bacteria,1QUXZ@1224|Proteobacteria	1224|Proteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
TLS2_k127_2334059_1	365044.Pnap_0226	1.737e-128	424.0	COG1609@1|root,COG1609@2|Bacteria,1MW7E@1224|Proteobacteria,2WFFC@28216|Betaproteobacteria,4AJ5N@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
TLS2_k127_2334059_0	864051.BurJ1DRAFT_4092	1.792e-157	505.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2VHAR@28216|Betaproteobacteria,1KK4Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	-	2.7.8.7,3.2.1.52	ko:K00997,ko:K01207	ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501	M00628	R00022,R01625,R05963,R07809,R07810,R10831	RC00002,RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
TLS2_k127_2334059_3	987059.RBXJA2T_06030	9.464e-63	220.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2VT0P@28216|Betaproteobacteria,1KKSJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
TLS2_k127_2334059_2	987059.RBXJA2T_06035	2.143e-116	386.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2VHY7@28216|Betaproteobacteria,1KJP1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
TLS2_k127_2334059_5	983917.RGE_40970	3.7e-36	139.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,2VJUC@28216|Betaproteobacteria,1KKNU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
TLS2_k127_234600_0	1223521.BBJX01000006_gene1651	4.867e-301	933.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2VHCS@28216|Betaproteobacteria,4A9UV@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
TLS2_k127_2347268_0	983917.RGE_44830	0.0	1354.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria,1KJYU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
TLS2_k127_2347268_1	987059.RBXJA2T_02682	4.803e-119	388.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria,1KJD9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	opaA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
TLS2_k127_2347300_1	983917.RGE_35080	1.401e-150	509.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2VI67@28216|Betaproteobacteria,1KK38@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
TLS2_k127_2347300_0	987059.RBXJA2T_18373	6.163e-250	776.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,1KIW5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	algC	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TLS2_k127_2361763_7	864051.BurJ1DRAFT_0344	1.418e-05	55.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2VH7F@28216|Betaproteobacteria,1KJ9I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
TLS2_k127_2361763_1	1123504.JQKD01000008_gene5449	1.286e-152	491.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2VIVJ@28216|Betaproteobacteria,4ABMK@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
TLS2_k127_2361763_2	983917.RGE_03090	1.273e-99	327.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria,1KJPK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EH	Glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
TLS2_k127_2361763_6	420662.Mpe_A2995	7.693e-11	63.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
TLS2_k127_2361763_4	330214.NIDE2814	7.26e-33	134.0	COG0607@1|root,COG0607@2|Bacteria,3J1F1@40117|Nitrospirae	40117|Nitrospirae	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS2_k127_2361763_0	1265502.KB905953_gene748	5.787e-245	760.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VI2V@28216|Betaproteobacteria,4A9Q6@80864|Comamonadaceae	28216|Betaproteobacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
TLS2_k127_2361763_5	864051.BurJ1DRAFT_0338	1.296e-25	108.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VI2V@28216|Betaproteobacteria,1KIVZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
TLS2_k127_2361763_3	983917.RGE_03070	1.355e-43	165.0	COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,2VU0N@28216|Betaproteobacteria,1KM7A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
TLS2_k127_2365259_6	1265502.KB905945_gene601	1.444e-36	147.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,2VR31@28216|Betaproteobacteria,4AE0X@80864|Comamonadaceae	28216|Betaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
TLS2_k127_2365259_2	864051.BurJ1DRAFT_1073	6.825e-146	466.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2VJ1J@28216|Betaproteobacteria,1KK7U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
TLS2_k127_2365259_0	983917.RGE_07630	3.289e-216	677.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,1KK1I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,S4_2,tRNA-synt_1b
TLS2_k127_2365259_1	987059.RBXJA2T_14411	8.211e-174	557.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VHBS@28216|Betaproteobacteria,1KIVP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS2_k127_2365259_3	987059.RBXJA2T_14421	9.983e-67	228.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,1KKSP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Required for insertion of 4Fe-4S clusters	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
TLS2_k127_2365259_4	864051.BurJ1DRAFT_1068	1.413e-49	180.0	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2VTZQ@28216|Betaproteobacteria,1KM73@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Polymer-forming cytoskeletal	ccmA	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
TLS2_k127_2365259_5	864051.BurJ1DRAFT_1067	8.299e-41	155.0	28IJP@1|root,2Z8KI@2|Bacteria,1R9DP@1224|Proteobacteria,2VHRX@28216|Betaproteobacteria,1KKMJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2379642_4	987059.RBXJA2T_16362	7.381e-29	120.0	2E54A@1|root,32ZX9@2|Bacteria,1N8HJ@1224|Proteobacteria,2VVW9@28216|Betaproteobacteria,1KMNY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1840)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1840
TLS2_k127_2379642_1	983917.RGE_44320	6.563e-106	348.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VJ4C@28216|Betaproteobacteria,1KK71@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Phosphatidylethanolamine-binding protein	bbsI	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
TLS2_k127_2379642_2	864051.BurJ1DRAFT_4508	2.467e-75	258.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2VQTE@28216|Betaproteobacteria,1KKM9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	phosphoglycerate mutase	gpmB	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
TLS2_k127_2379642_0	420662.Mpe_A0327	7.606e-190	608.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2VH0J@28216|Betaproteobacteria,1KKGH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
TLS2_k127_2379642_3	1123487.KB892839_gene152	5.238e-37	145.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2VTY7@28216|Betaproteobacteria,2KWMU@206389|Rhodocyclales	206389|Rhodocyclales	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
TLS2_k127_238426_2	983917.RGE_23750	3.044e-169	535.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH50@28216|Betaproteobacteria,1KJB7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Poly(R)-hydroxyalkanoic acid synthase, class I	phbC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
TLS2_k127_238426_1	395495.Lcho_2086	4.055e-214	674.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,1KJB6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Belongs to the thiolase family	phbA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
TLS2_k127_238426_4	983917.RGE_23770	2.438e-138	442.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2VH8R@28216|Betaproteobacteria,1KIVJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	phbB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
TLS2_k127_238426_6	987059.RBXJA2T_08260	6.718e-28	126.0	2DNMC@1|root,32Y3R@2|Bacteria,1N8DI@1224|Proteobacteria,2VVNN@28216|Betaproteobacteria,1KMH0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2788)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2788
TLS2_k127_238426_5	864051.BurJ1DRAFT_2251	1.135e-94	317.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2VK3K@28216|Betaproteobacteria,1KKMW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
TLS2_k127_238426_3	983917.RGE_23810	3.29e-146	475.0	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,2VIMH@28216|Betaproteobacteria,1KJPD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
TLS2_k127_238426_0	864051.BurJ1DRAFT_2255	0.0	1311.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2VI2G@28216|Betaproteobacteria,1KJ53@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
TLS2_k127_2390590_0	987059.RBXJA2T_04153	8.962e-193	608.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,2VIC0@28216|Betaproteobacteria,1KJ02@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
TLS2_k127_2390590_3	987059.RBXJA2T_04158	2.489e-56	200.0	COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,2VUG8@28216|Betaproteobacteria,1KMCQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	uraH	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
TLS2_k127_2390590_1	1265502.KB905932_gene1779	1.518e-179	571.0	COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2VJQR@28216|Betaproteobacteria,4AA38@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Polysaccharide deacetylase	-	-	3.5.1.41	ko:K01452	ko00520,ko01100,map00520,map01100	-	R02333	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Polysacc_deac_1
TLS2_k127_2390590_2	1538295.JY96_02680	2.501e-83	296.0	COG0624@1|root,COG3195@1|root,COG0624@2|Bacteria,COG3195@2|Bacteria,1MVUX@1224|Proteobacteria,2VIGB@28216|Betaproteobacteria,1KK6M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	OHCU decarboxylase	uraD	-	3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00905,R02423,R04666	RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,OHCU_decarbox,Peptidase_M20,Peptidase_M28
TLS2_k127_2418509_2	987059.RBXJA2T_18343	1.11e-62	229.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2VJN2@28216|Betaproteobacteria,1KJ2F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
TLS2_k127_2418509_0	1000565.METUNv1_03450	1.384e-239	747.0	COG0280@1|root,COG2030@1|root,COG0280@2|Bacteria,COG2030@2|Bacteria,1MWPK@1224|Proteobacteria,2WGKC@28216|Betaproteobacteria,2KV8I@206389|Rhodocyclales	206389|Rhodocyclales	CI	Bifunctional enoyl-CoA hydratase phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas,PTA_PTB
TLS2_k127_2418509_3	983917.RGE_35000	1.582e-57	213.0	COG2199@1|root,COG2199@2|Bacteria,1RGJM@1224|Proteobacteria,2VRG5@28216|Betaproteobacteria,1KKYZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
TLS2_k127_2418509_1	420662.Mpe_A2324	7.043e-188	590.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHGR@28216|Betaproteobacteria,1KJGK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS2_k127_244906_3	420662.Mpe_A3639	1.483e-29	119.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2VHUQ@28216|Betaproteobacteria,1KK50@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	glcE	-	1.1.3.15	ko:K00104,ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
TLS2_k127_244906_2	983917.RGE_01980	3.997e-100	330.0	COG0500@1|root,COG0500@2|Bacteria,1R1VS@1224|Proteobacteria,2WI6B@28216|Betaproteobacteria,1KN16@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS2_k127_244906_0	1265502.KB905968_gene1258	2.668e-212	670.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VISA@28216|Betaproteobacteria,4AAZ5@80864|Comamonadaceae	28216|Betaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
TLS2_k127_244906_1	420662.Mpe_A3644	3.142e-150	483.0	COG0697@1|root,COG0697@2|Bacteria,1MW7P@1224|Proteobacteria,2VHDI@28216|Betaproteobacteria,1KKBB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	ytfF	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS2_k127_2478427_3	983917.RGE_29080	1.622e-125	405.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VJIJ@28216|Betaproteobacteria,1KKEV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
TLS2_k127_2478427_0	983917.RGE_29090	0.0	1190.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,2W14D@28216|Betaproteobacteria,1KPC9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Alpha amylase, C-terminal all-beta domain	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
TLS2_k127_2478427_1	365044.Pnap_1103	2.349e-292	918.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,2VH8E@28216|Betaproteobacteria,4AC1I@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM glycoside hydrolase, family 13 domain protein	glgX	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
TLS2_k127_2478427_2	983917.RGE_29110	6.632e-248	773.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,2VJUV@28216|Betaproteobacteria,1KK55@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
TLS2_k127_2478427_4	395495.Lcho_1327	9.521e-45	170.0	COG1191@1|root,COG1191@2|Bacteria,1NU0U@1224|Proteobacteria,2VZXG@28216|Betaproteobacteria,1KNDG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r4
TLS2_k127_2552142_2	314278.NB231_08993	1.191e-17	89.0	COG4731@1|root,COG4731@2|Bacteria,1QDFH@1224|Proteobacteria,1SF5X@1236|Gammaproteobacteria,1X1JN@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
TLS2_k127_2552142_0	1458275.AZ34_12195	2.02e-150	486.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VIK8@28216|Betaproteobacteria,4A9SJ@80864|Comamonadaceae	28216|Betaproteobacteria	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
TLS2_k127_2552142_1	864051.BurJ1DRAFT_2485	6.173e-139	446.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,1KK5U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
TLS2_k127_2556362_1	864051.BurJ1DRAFT_2789	1.299e-128	430.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,2VH5Q@28216|Betaproteobacteria,1KIZ8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
TLS2_k127_2556362_0	420662.Mpe_A1389	9.828e-143	460.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2VHEW@28216|Betaproteobacteria,1KJNZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
TLS2_k127_2556362_2	420662.Mpe_A2256	5.828e-98	326.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VH1Z@28216|Betaproteobacteria,1KK0B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
TLS2_k127_2563331_1	864051.BurJ1DRAFT_1697	1.247e-22	102.0	COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,2VHU2@28216|Betaproteobacteria,1KJT5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
TLS2_k127_2563331_0	864051.BurJ1DRAFT_4157	1.246e-210	662.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria,1KJVF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
TLS2_k127_2563331_2	983917.RGE_07400	1.049e-08	63.0	2BYRU@1|root,345X8@2|Bacteria,1P3V4@1224|Proteobacteria,2W4JW@28216|Betaproteobacteria,1KNVI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2572616_5	983917.RGE_27240	5.373e-22	106.0	COG0566@1|root,COG0566@2|Bacteria,1R9JA@1224|Proteobacteria,2VQDG@28216|Betaproteobacteria,1KK2B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	rRNA methyltransferase	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
TLS2_k127_2572616_3	1276756.AUEX01000019_gene3473	8.702e-80	274.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,4AAT9@80864|Comamonadaceae	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
TLS2_k127_2572616_0	983917.RGE_27260	2.717e-172	561.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2VIBP@28216|Betaproteobacteria,1KIVK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
TLS2_k127_2572616_1	987059.RBXJA2T_18061	4.026e-125	406.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,1KJZZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
TLS2_k127_2572616_4	987059.RBXJA2T_18056	1.393e-67	233.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2VRKQ@28216|Betaproteobacteria,1KKQC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
TLS2_k127_2572616_2	864051.BurJ1DRAFT_2925	7.626e-109	355.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,1KK6E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
TLS2_k127_2573724_1	864051.BurJ1DRAFT_3589	6.478e-161	512.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,2VH8K@28216|Betaproteobacteria,1KJVI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	L-serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
TLS2_k127_2573724_2	768671.ThimaDRAFT_4079	2.393e-44	176.0	COG2863@1|root,COG2863@2|Bacteria,1RCAT@1224|Proteobacteria,1T09H@1236|Gammaproteobacteria,1X2M4@135613|Chromatiales	135613|Chromatiales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2573724_0	864051.BurJ1DRAFT_3587	0.0	1320.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,1KJKP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
TLS2_k127_2573773_0	1454004.AW11_02182	3.175e-100	344.0	2DBVG@1|root,2ZBB1@2|Bacteria,1N1MS@1224|Proteobacteria,2VPUQ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2573773_1	864051.BurJ1DRAFT_3178	9.842e-28	125.0	2DBVG@1|root,2ZBB1@2|Bacteria,1N1MS@1224|Proteobacteria,2VPUQ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2587087_1	864051.BurJ1DRAFT_4302	9.733e-192	604.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VJIV@28216|Betaproteobacteria,1KIWA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
TLS2_k127_2587087_0	987059.RBXJA2T_11723	5.472e-210	663.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KK0F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	response regulator	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS2_k127_2587087_2	987059.RBXJA2T_11718	8.944e-116	381.0	COG4191@1|root,COG4191@2|Bacteria,1QU7R@1224|Proteobacteria,2VICU@28216|Betaproteobacteria,1KPCM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	pilS	-	2.7.13.3	ko:K02668,ko:K10125	ko02020,map02020	M00501,M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_8
TLS2_k127_2592702_2	983917.RGE_33920	3.522e-61	220.0	COG0784@1|root,COG2202@1|root,COG3852@1|root,COG4191@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,2VHTK@28216|Betaproteobacteria,1KNP0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	DUF3365,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,Response_reg
TLS2_k127_2592702_0	1538295.JY96_02705	1.138e-133	437.0	COG0715@1|root,COG0715@2|Bacteria,1MXA3@1224|Proteobacteria,2VI0Z@28216|Betaproteobacteria,1KKQQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
TLS2_k127_2592702_1	543728.Vapar_4759	2.028e-87	321.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2VH99@28216|Betaproteobacteria,4AC0T@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
TLS2_k127_2595334_5	375286.mma_1989	9.38e-07	57.0	2EPNT@1|root,33H9E@2|Bacteria,1NI6Z@1224|Proteobacteria,2VXVE@28216|Betaproteobacteria,4755C@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4936)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4936
TLS2_k127_2595334_1	266834.SM_b20135	3.882e-75	259.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2U5GN@28211|Alphaproteobacteria,4BE86@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
TLS2_k127_2595334_0	1198452.Jab_1c08050	2.49e-92	310.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria	1224|Proteobacteria	KT	Response regulator of the LytR AlgR family	-	GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS2_k127_2595334_3	864051.BurJ1DRAFT_2302	2.782e-48	195.0	2E2V3@1|root,32XWV@2|Bacteria,1MZBD@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2595334_2	1198452.Jab_1c08060	9.938e-65	237.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VRIK@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS2_k127_2595334_4	983917.RGE_35090	1.656e-25	109.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,1KIW5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	algC	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TLS2_k127_259578_2	395495.Lcho_1722	2.513e-50	183.0	COG3638@1|root,COG3638@2|Bacteria,1MXYA@1224|Proteobacteria,2VM4F@28216|Betaproteobacteria,1KP95@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
TLS2_k127_259578_0	395495.Lcho_1723	1.33e-147	475.0	COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,2VMDZ@28216|Betaproteobacteria,1KKN5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
TLS2_k127_259578_1	395495.Lcho_1724	4.624e-68	238.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,2VJHK@28216|Betaproteobacteria,1KKKR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Histidine-specific methyltransferase, SAM-dependent	egtD	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
TLS2_k127_2596998_2	1215092.PA6_046_00060	4.101e-158	514.0	COG2375@1|root,COG2375@2|Bacteria,1QWF4@1224|Proteobacteria,1T59S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
TLS2_k127_2596998_0	497321.C664_01965	0.0	1260.0	COG3299@1|root,COG3299@2|Bacteria,1MWKI@1224|Proteobacteria,2VI5M@28216|Betaproteobacteria	28216|Betaproteobacteria	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
TLS2_k127_2596998_5	1215092.PA6_046_00080	2.742e-51	189.0	COG3628@1|root,COG3628@2|Bacteria,1N039@1224|Proteobacteria,1SXRI@1236|Gammaproteobacteria,1YKB8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Gene 25-like lysozyme	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
TLS2_k127_2596998_4	1122599.AUGR01000019_gene3066	3.44e-57	199.0	2CE1N@1|root,32RYY@2|Bacteria,1N23N@1224|Proteobacteria,1S6JJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2596998_3	765912.Thimo_0790	1.156e-90	301.0	COG3501@1|root,COG3501@2|Bacteria,1R540@1224|Proteobacteria,1RTBU@1236|Gammaproteobacteria,1X1J3@135613|Chromatiales	135613|Chromatiales	S	Baseplate assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2596998_1	596154.Alide2_3988	3.337e-193	608.0	COG3500@1|root,COG3500@2|Bacteria,1Q2U5@1224|Proteobacteria,2VMWF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Late control gene D protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2596998_6	1215092.PA6_046_00120	1.369e-46	173.0	COG1652@1|root,COG1652@2|Bacteria,1N0XA@1224|Proteobacteria,1SC15@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2596998_7	1123392.AQWL01000008_gene1230	2.562e-22	97.0	2CI52@1|root,2ZC5H@2|Bacteria,1R9WI@1224|Proteobacteria,2VQZX@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2599734_3	33876.JNXY01000008_gene8499	3.243e-07	53.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DARM@85008|Micromonosporales	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
TLS2_k127_2599734_0	570967.JMLV01000002_gene1584	2.346e-178	578.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,2TRTV@28211|Alphaproteobacteria,2JRRJ@204441|Rhodospirillales	204441|Rhodospirillales	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
TLS2_k127_2599734_2	196367.JNFG01000041_gene7819	1.754e-18	91.0	COG4251@1|root,COG4251@2|Bacteria,1N1KJ@1224|Proteobacteria	1224|Proteobacteria	T	KaiB domain protein	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
TLS2_k127_2599734_1	1121015.N789_03870	1.371e-23	110.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1X3PH@135614|Xanthomonadales	135614|Xanthomonadales	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,HAMP,PAS,PAS_3,PAS_9,Response_reg
TLS2_k127_2605317_4	1038866.KB902790_gene3547	4.538e-20	91.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2TV23@28211|Alphaproteobacteria,3JSS1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Peptidase family M28	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
TLS2_k127_2605317_2	864051.BurJ1DRAFT_3907	4.235e-150	493.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VI5Z@28216|Betaproteobacteria,1KJMV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	ko:K18336	ko00051,ko01120,map00051,map01120	-	R10691	RC00326,RC03236	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
TLS2_k127_2605317_3	983917.RGE_13290	6.07e-109	358.0	COG4221@1|root,COG4221@2|Bacteria,1MWXS@1224|Proteobacteria,2VHSZ@28216|Betaproteobacteria,1KJP3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS2_k127_2605317_1	983917.RGE_13320	4.528e-188	591.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,1KJGX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
TLS2_k127_2605317_0	983917.RGE_13330	1.01e-200	631.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,1KJFK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	acetylornithine	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS2_k127_2612107_1	1333856.L686_10160	4.648e-159	507.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,1RMPQ@1236|Gammaproteobacteria,1Z1NW@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
TLS2_k127_2612107_3	1385515.N791_13835	9.008e-13	77.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS2_k127_2612107_0	1390370.O203_17740	8.913e-207	661.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,1RMIY@1236|Gammaproteobacteria,1YDUM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008446,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
TLS2_k127_2612107_2	395493.BegalDRAFT_1047	3.946e-120	415.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RXZA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Type II secretory pathway, component PulD	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
TLS2_k127_2620295_0	987059.RBXJA2T_01710	0.0	1072.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,2VKWB@28216|Betaproteobacteria,1KJI7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
TLS2_k127_2620295_1	983917.RGE_43920	6.177e-73	254.0	2CI4X@1|root,33KFB@2|Bacteria,1NMX9@1224|Proteobacteria,2VXT3@28216|Betaproteobacteria,1KMSX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2644263_3	365046.Rta_04000	1.037e-98	344.0	COG1252@1|root,COG1252@2|Bacteria,1QUKT@1224|Proteobacteria,2WGU5@28216|Betaproteobacteria,4ADZF@80864|Comamonadaceae	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS2_k127_2644263_6	365046.Rta_03940	2.017e-66	236.0	COG1215@1|root,COG3222@1|root,COG1215@2|Bacteria,COG3222@2|Bacteria,1RA75@1224|Proteobacteria,2VQQD@28216|Betaproteobacteria,4ADRH@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS2_k127_2644263_2	864051.BurJ1DRAFT_3429	3.827e-104	353.0	COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,2VQQD@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS2_k127_2644263_4	1348657.M622_03195	7.579e-92	312.0	28JXP@1|root,2Z9N4@2|Bacteria,1MXG4@1224|Proteobacteria,2W448@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2644263_0	1348657.M622_06600	4.479e-254	796.0	COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VH3T@28216|Betaproteobacteria,2KUS4@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
TLS2_k127_2644263_5	522306.CAP2UW1_2826	2.103e-83	287.0	COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VH3T@28216|Betaproteobacteria,1KQAC@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	SNARE associated Golgi protein	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
TLS2_k127_2644263_9	338969.Rfer_1608	6.364e-35	137.0	COG5572@1|root,COG5572@2|Bacteria,1MZ6Q@1224|Proteobacteria,2VV7D@28216|Betaproteobacteria,4AF57@80864|Comamonadaceae	28216|Betaproteobacteria	S	Predicted integral membrane protein (DUF2282)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2282
TLS2_k127_2644263_1	1149133.ppKF707_2899	3.644e-124	411.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,1YHKE@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
TLS2_k127_2644263_7	1245471.PCA10_31160	1.532e-64	239.0	COG3219@1|root,COG3219@2|Bacteria,1QAP4@1224|Proteobacteria,1S0G6@1236|Gammaproteobacteria,1YH3V@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2063
TLS2_k127_2644263_8	587753.EY04_05915	2.361e-58	211.0	COG2259@1|root,COG2259@2|Bacteria,1N1VA@1224|Proteobacteria,1S7MH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DoxX family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
TLS2_k127_2648338_0	987059.RBXJA2T_17087	3.469e-188	595.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VM1X@28216|Betaproteobacteria,1KIZB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	general secretion pathway protein	gspF	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
TLS2_k127_2648338_2	983917.RGE_10420	1.08e-129	422.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2VI2H@28216|Betaproteobacteria,1KJ6N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
TLS2_k127_2648338_5	983917.RGE_10410	1.949e-59	212.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2VVPX@28216|Betaproteobacteria,1KKZA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
TLS2_k127_2648338_10	987059.RBXJA2T_06925	1.438e-29	120.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,1KMNQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
TLS2_k127_2648338_9	987059.RBXJA2T_06920	6.084e-33	127.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2VSMS@28216|Betaproteobacteria,1KM2P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hitA	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
TLS2_k127_2648338_11	864051.BurJ1DRAFT_1222	4.842e-18	93.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2VSMS@28216|Betaproteobacteria,1KM2P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hitA	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
TLS2_k127_2648338_6	864051.BurJ1DRAFT_1221	3.202e-55	201.0	COG3671@1|root,COG3671@2|Bacteria,1N51H@1224|Proteobacteria,2VUKZ@28216|Betaproteobacteria,1KM72@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2648338_7	420662.Mpe_A0838	1.844e-51	184.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2VUN8@28216|Betaproteobacteria,1KM5H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
TLS2_k127_2648338_4	987059.RBXJA2T_06905	1.806e-63	219.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,1KKTY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
TLS2_k127_2648338_3	983917.RGE_10350	2.666e-70	245.0	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2VHTP@28216|Betaproteobacteria,1KKVF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,TMP-TENI
TLS2_k127_2648338_1	987059.RBXJA2T_06895	3.565e-150	486.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,2VID5@28216|Betaproteobacteria,1KJNB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF815)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
TLS2_k127_2648338_8	987059.RBXJA2T_06885	3.291e-44	162.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VQ4C@28216|Betaproteobacteria,1KK77@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	slmA	-	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
TLS2_k127_2654049_1	420662.Mpe_A2071	1.567e-132	426.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,1KJRR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	exodeoxyribonuclease III	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
TLS2_k127_2654049_0	420662.Mpe_A2664	1.198e-160	521.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KJEE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,HAMP,PAS_4,PAS_9,Response_reg
TLS2_k127_2678379_2	358220.C380_09535	9.749e-31	123.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria,4AES2@80864|Comamonadaceae	28216|Betaproteobacteria	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
TLS2_k127_2678379_1	1163409.UUA_04623	8.136e-81	276.0	COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria,1T095@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
TLS2_k127_2678379_0	365044.Pnap_1535	4.604e-107	351.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VHIS@28216|Betaproteobacteria,4ADAK@80864|Comamonadaceae	28216|Betaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS2_k127_2697393_0	987059.RBXJA2T_17342	2.379e-283	880.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2VIYX@28216|Betaproteobacteria,1KK6P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Sulfite reductase	cysI	-	1.8.1.2,1.8.7.1	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858,R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
TLS2_k127_2697393_1	983917.RGE_23450	4.155e-37	145.0	COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,2VSQB@28216|Betaproteobacteria,1KKSK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF934
TLS2_k127_2697393_2	420662.Mpe_A1501	1.81e-19	98.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,2VIR0@28216|Betaproteobacteria,1KKCV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
TLS2_k127_2704329_1	983917.RGE_35440	4.782e-98	322.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2VI13@28216|Betaproteobacteria,1KJEP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
TLS2_k127_2704329_0	987059.RBXJA2T_18548	1.983e-162	519.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,1KKAT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
TLS2_k127_2740811_3	987059.RBXJA2T_06205	7.804e-73	251.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,2VRJF@28216|Betaproteobacteria,1KKTZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
TLS2_k127_2740811_0	983917.RGE_04520	0.0	1139.0	COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,2VNCR@28216|Betaproteobacteria,1KKHC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
TLS2_k127_2740811_2	983917.RGE_04510	7.003e-170	539.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2VHZG@28216|Betaproteobacteria,1KJQZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
TLS2_k127_2740811_1	420662.Mpe_A0277	3.442e-251	789.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,1KJEI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
TLS2_k127_2748373_1	983917.RGE_24140	3.144e-53	192.0	COG3115@1|root,COG3115@2|Bacteria,1QW35@1224|Proteobacteria,2WI64@28216|Betaproteobacteria,1KJ0Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2748373_0	983917.RGE_24130	1.077e-90	300.0	COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2VQ0U@28216|Betaproteobacteria,1KKMP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
TLS2_k127_2748373_2	29581.BW37_04580	2.426e-45	170.0	COG1056@1|root,COG3172@1|root,COG1056@2|Bacteria,COG3172@2|Bacteria,1MUSI@1224|Proteobacteria,2WFVU@28216|Betaproteobacteria	28216|Betaproteobacteria	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
TLS2_k127_2748373_4	864051.BurJ1DRAFT_2048	1.484e-30	121.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,1KKET@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
TLS2_k127_2748373_3	864051.BurJ1DRAFT_2048	3.06e-32	129.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,1KKET@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
TLS2_k127_2782204_0	864051.BurJ1DRAFT_3299	1.081e-261	811.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VI3F@28216|Betaproteobacteria,1KJIC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS2_k127_2782204_1	864051.BurJ1DRAFT_3300	5.523e-65	225.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,2VR2G@28216|Betaproteobacteria,1KM2J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Thioredoxin	trxC	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
TLS2_k127_2787732_4	1276756.AUEX01000011_gene1248	7.249e-46	166.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VIA5@28216|Betaproteobacteria,4AANU@80864|Comamonadaceae	28216|Betaproteobacteria	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
TLS2_k127_2787732_0	864051.BurJ1DRAFT_3778	2.703e-201	638.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2VH9J@28216|Betaproteobacteria,1KJD8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
TLS2_k127_2787732_2	614083.AWQR01000018_gene1782	3.799e-61	219.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,2VT33@28216|Betaproteobacteria,4AEK7@80864|Comamonadaceae	28216|Betaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TLS2_k127_2787732_1	983917.RGE_38520	3.718e-153	505.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,1KJMH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
TLS2_k127_2787732_3	987059.RBXJA2T_00250	8.429e-47	188.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria,1KM1Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
TLS2_k127_2821491_1	987059.RBXJA2T_12152	1.207e-117	388.0	COG1028@1|root,COG1028@2|Bacteria,1N907@1224|Proteobacteria,2VJ81@28216|Betaproteobacteria,1KJSH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	fabG2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS2_k127_2821491_0	983917.RGE_42190	1.806e-126	409.0	COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,1KIW8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	RNB	rnb	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
TLS2_k127_2827461_3	1095769.CAHF01000022_gene224	8.018e-45	165.0	COG0329@1|root,COG0329@2|Bacteria,1MWV5@1224|Proteobacteria,2VMFS@28216|Betaproteobacteria	28216|Betaproteobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
TLS2_k127_2827461_1	338969.Rfer_4003	6.44e-59	216.0	COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,2VIHJ@28216|Betaproteobacteria,4AB02@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3014)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3014
TLS2_k127_2827461_0	338963.Pcar_2866	8.169e-221	707.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42MPU@68525|delta/epsilon subdivisions,2WIJ1@28221|Deltaproteobacteria,43UNQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
TLS2_k127_2827461_2	338963.Pcar_2867	5.434e-56	205.0	COG3005@1|root,COG3005@2|Bacteria,1N0I4@1224|Proteobacteria,42R1B@68525|delta/epsilon subdivisions,2WQMW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	nrfH	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
TLS2_k127_2827461_4	397945.Aave_1572	2.922e-13	72.0	COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,2VU41@28216|Betaproteobacteria,4AECT@80864|Comamonadaceae	28216|Betaproteobacteria	K	transcriptional regulator, Rrf2 family	nsrR	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
TLS2_k127_2827550_3	420662.Mpe_A2305	2.626e-73	264.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,2VMI0@28216|Betaproteobacteria,1KJJN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	HP	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
TLS2_k127_2827550_1	395495.Lcho_2663	1.417e-98	333.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2VK1S@28216|Betaproteobacteria,1KIZD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
TLS2_k127_2827550_2	1286631.X805_38420	5.483e-85	295.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,2VJ7T@28216|Betaproteobacteria,1KK88@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Periplasmic binding protein	btuF	-	-	ko:K02016,ko:K06858	ko02010,map02010	M00240,M00241	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.13,3.A.1.14	-	-	Peripla_BP_2
TLS2_k127_2827550_0	983917.RGE_15030	5.707e-135	441.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2VH64@28216|Betaproteobacteria,1KJFR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	outer membrane cobalamin receptor	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
TLS2_k127_2832604_1	864051.BurJ1DRAFT_2624	3.846e-53	191.0	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,2VHW7@28216|Betaproteobacteria,1KK73@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
TLS2_k127_2832604_3	1121127.JAFA01000019_gene573	5.533e-25	109.0	COG1018@1|root,COG1018@2|Bacteria,1MU6E@1224|Proteobacteria,2VK6Y@28216|Betaproteobacteria,1K1R8@119060|Burkholderiaceae	28216|Betaproteobacteria	C	oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	ko:K03863	ko00627,ko01120,map00627,map01120	-	R05274	RC00392,RC01533	ko00000,ko00001	-	-	-	Fer2,NAD_binding_1
TLS2_k127_2832604_4	85643.Tmz1t_0307	0.0006157	48.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1QU9I@1224|Proteobacteria,2VHI0@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Type III restriction	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
TLS2_k127_2832604_0	420662.Mpe_A0010	7.702e-206	645.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2VIY1@28216|Betaproteobacteria,1KMFQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Fic/DOC family N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N,HTH_13,HTH_24
TLS2_k127_2832604_2	399739.Pmen_0568	4.298e-39	147.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,1S9E4@1236|Gammaproteobacteria,1YKCM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
TLS2_k127_2832965_9	395495.Lcho_4206	5.66e-49	184.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2VNUR@28216|Betaproteobacteria,1KMA4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Lysine exporter protein LysE	leuE_1	-	-	ko:K11250	-	-	-	-	ko00000,ko02000	2.A.76.1.5	-	-	LysE
TLS2_k127_2832965_3	987059.RBXJA2T_02991	5.749e-199	629.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,1KJCD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
TLS2_k127_2832965_1	983917.RGE_43530	7.796e-315	971.0	COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,2VJMA@28216|Betaproteobacteria,1KJHG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation	aceK	-	2.7.11.5	ko:K00906	-	-	-	-	ko00000,ko01000	-	-	-	AceK
TLS2_k127_2832965_6	864051.BurJ1DRAFT_0508	5.072e-108	353.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VIBS@28216|Betaproteobacteria,1KJR5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Reversible hydration of carbon dioxide	can	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Pro_CA
TLS2_k127_2832965_10	388051.AUFE01000122_gene1894	0.0001945	46.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHD3@28216|Betaproteobacteria,1K0AV@119060|Burkholderiaceae	28216|Betaproteobacteria	C	dehydrogenase	ivd	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS2_k127_2832965_2	365046.Rta_05640	1.236e-235	731.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHD3@28216|Betaproteobacteria,4A9Q4@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	ivd	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS2_k127_2832965_4	864051.BurJ1DRAFT_0507	8.828e-118	385.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2VNC5@28216|Betaproteobacteria,1KJKY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
TLS2_k127_2832965_5	395495.Lcho_0213	1.927e-111	365.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2VNAX@28216|Betaproteobacteria,1KK48@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Phosphate acyltransferases	nlaB	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS2_k127_2832965_8	983917.RGE_43650	2.68e-81	279.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2VQ49@28216|Betaproteobacteria,1KKN0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase,Hydrolase_like,PNK3P
TLS2_k127_2832965_0	987059.RBXJA2T_02946	8.499e-316	988.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2VICG@28216|Betaproteobacteria,1KIYN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
TLS2_k127_2832965_7	987059.RBXJA2T_02941	5.263e-86	286.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2VIQX@28216|Betaproteobacteria,1KKBS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
TLS2_k127_2841369_0	765914.ThisiDRAFT_1964	2.37e-264	823.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1WW72@135613|Chromatiales	135613|Chromatiales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
TLS2_k127_2841369_2	765914.ThisiDRAFT_1963	1.534e-117	383.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RSQ8@1236|Gammaproteobacteria,1WWKV@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM Succinate dehydrogenase fumarate reductase iron-sulphur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
TLS2_k127_2841369_1	640081.Dsui_3155	4.577e-141	453.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria,2KV1X@206389|Rhodocyclales	206389|Rhodocyclales	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
TLS2_k127_2850693_2	983917.RGE_07770	1.745e-153	492.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,1KJ2V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS2_k127_2850693_4	987059.RBXJA2T_17157	2.08e-109	359.0	COG0664@1|root,COG0664@2|Bacteria,1MUHT@1224|Proteobacteria,2VI43@28216|Betaproteobacteria,1KJG7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
TLS2_k127_2850693_0	987059.RBXJA2T_17162	0.0	1080.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,1KJ66@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
TLS2_k127_2850693_3	983917.RGE_07740	2.603e-141	462.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJ0Q@28216|Betaproteobacteria,1KJHD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
TLS2_k127_2850693_1	1286631.X805_33600	1.808e-160	509.0	COG0559@1|root,COG0559@2|Bacteria,1N54M@1224|Proteobacteria,2VIID@28216|Betaproteobacteria,1KJQG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
TLS2_k127_285508_1	1265502.KB905932_gene1797	2.009e-272	850.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria,4ABBZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
TLS2_k127_285508_3	1223521.BBJX01000004_gene2292	1.388e-30	127.0	COG4729@1|root,COG4729@2|Bacteria,1N0MH@1224|Proteobacteria,2VWUT@28216|Betaproteobacteria,4AFSV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF1850)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1850
TLS2_k127_285508_0	1437824.BN940_01676	9.982e-314	973.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria,3T1N0@506|Alcaligenaceae	28216|Betaproteobacteria	S	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	DctM
TLS2_k127_285508_2	1223521.BBJX01000004_gene2294	8.182e-148	471.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2VMR0@28216|Betaproteobacteria,4AJ4U@80864|Comamonadaceae	28216|Betaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
TLS2_k127_2870355_4	1265502.KB905943_gene2723	8.496e-20	91.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,4AD1S@80864|Comamonadaceae	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
TLS2_k127_2870355_3	1265502.KB905943_gene2722	9.329e-36	143.0	COG3063@1|root,COG3063@2|Bacteria,1N7DT@1224|Proteobacteria,2VW37@28216|Betaproteobacteria,4AFTV@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2870355_1	338969.Rfer_1529	2.793e-52	187.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2VUEV@28216|Betaproteobacteria,4AEEQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM thioesterase superfamily protein	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
TLS2_k127_2870355_0	987059.RBXJA2T_06775	2.807e-114	374.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2VJPW@28216|Betaproteobacteria,1KK10@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	tolQ	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
TLS2_k127_2870355_2	983917.RGE_39120	5.676e-51	190.0	COG0848@1|root,COG0848@2|Bacteria,1RGWR@1224|Proteobacteria,2VT20@28216|Betaproteobacteria,1KM2W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
TLS2_k127_2870355_5	864051.BurJ1DRAFT_1556	3.267e-07	55.0	COG3064@1|root,COG3064@2|Bacteria,1RKZU@1224|Proteobacteria,2WGP5@28216|Betaproteobacteria,1KPDJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	TonB C terminal	tolA	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
TLS2_k127_2880128_1	983917.RGE_16700	9.802e-135	434.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,2VIC9@28216|Betaproteobacteria,1KJFI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
TLS2_k127_2880128_0	983917.RGE_16690	0.0	1091.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2VHXG@28216|Betaproteobacteria,1KJ7W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
TLS2_k127_2881052_2	420662.Mpe_A2228	8.09e-18	83.0	2BKYI@1|root,32FF5@2|Bacteria,1MY1A@1224|Proteobacteria,2VRUQ@28216|Betaproteobacteria,1KNWV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
TLS2_k127_2881052_3	987059.RBXJA2T_17152	6.107e-06	49.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,1KJ2V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS2_k127_2881052_0	987059.RBXJA2T_16902	1.198e-154	492.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2VJBW@28216|Betaproteobacteria,1KKE4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
TLS2_k127_2881052_1	1268622.AVS7_01574	2.7e-151	481.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,4AAUZ@80864|Comamonadaceae	28216|Betaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
TLS2_k127_2886109_2	196162.Noca_3874	8.132e-36	138.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4DQBP@85009|Propionibacteriales	201174|Actinobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
TLS2_k127_2886109_0	983917.RGE_15540	1.218e-153	496.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2VHCB@28216|Betaproteobacteria,1KJ1A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NAD(P)H quinone oxidoreductase, PIG3 family	qor1	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS2_k127_2886109_1	987059.RBXJA2T_12667	2.091e-128	414.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2VIRP@28216|Betaproteobacteria,1KK1K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
TLS2_k127_2886109_3	1265502.KB905936_gene2665	7.188e-10	60.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2VU0P@28216|Betaproteobacteria,4AEHQ@80864|Comamonadaceae	28216|Betaproteobacteria	U	PFAM Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
TLS2_k127_2895309_3	338969.Rfer_0694	5.172e-63	233.0	COG1073@1|root,COG1073@2|Bacteria,1R61B@1224|Proteobacteria,2VQGB@28216|Betaproteobacteria,4AD7C@80864|Comamonadaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
TLS2_k127_2895309_1	338969.Rfer_0697	4.949e-95	319.0	COG1073@1|root,COG1073@2|Bacteria,1RA0U@1224|Proteobacteria,2VQ78@28216|Betaproteobacteria,4ACM1@80864|Comamonadaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
TLS2_k127_2895309_5	338969.Rfer_0698	4.094e-29	123.0	COG0236@1|root,COG0236@2|Bacteria,1N83X@1224|Proteobacteria,2VW0V@28216|Betaproteobacteria,4AF6H@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
TLS2_k127_2895309_0	864051.BurJ1DRAFT_3156	8.395e-268	832.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VJQV@28216|Betaproteobacteria,1KKI1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	AMP-binding enzyme	fadD	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
TLS2_k127_2895309_2	1144275.COCOR_02268	1.11e-63	234.0	COG1835@1|root,COG1835@2|Bacteria,1PHPS@1224|Proteobacteria,431KP@68525|delta/epsilon subdivisions,2WWPH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS2_k127_2895309_4	1266925.JHVX01000005_gene1944	1.155e-55	207.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,2VUX2@28216|Betaproteobacteria,3736Y@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_transf_7C,Glycos_transf_2,PIG-L
TLS2_k127_290600_0	987059.RBXJA2T_07060	5.998e-208	652.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VGZI@28216|Betaproteobacteria,1KJ0H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TLS2_k127_290600_1	323848.Nmul_A0297	3.503e-09	60.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,2VUX2@28216|Betaproteobacteria,3736Y@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_transf_7C,Glycos_transf_2,PIG-L
TLS2_k127_2911642_0	420662.Mpe_A3177	1.672e-151	482.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VJAP@28216|Betaproteobacteria,1KJDY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c oxidase subunit	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
TLS2_k127_2911642_1	420662.Mpe_A3176	2.698e-76	265.0	COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,2VSAZ@28216|Betaproteobacteria,1KKUG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	SURF1-like protein	surf1	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
TLS2_k127_2911642_2	543728.Vapar_4384	1.561e-23	106.0	COG1999@1|root,COG1999@2|Bacteria,1RHK3@1224|Proteobacteria,2VRBY@28216|Betaproteobacteria,4A9Y4@80864|Comamonadaceae	28216|Betaproteobacteria	S	signal sequence binding	sco1	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2915324_1	1538295.JY96_20055	0.0	1063.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2VHBQ@28216|Betaproteobacteria,1KJW7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TLS2_k127_2915324_3	864051.BurJ1DRAFT_2816	3.723e-82	276.0	COG1670@1|root,COG1670@2|Bacteria,1PDMH@1224|Proteobacteria,2VS7P@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS2_k127_2915324_2	1005048.CFU_3179	2.976e-190	616.0	COG0339@1|root,COG0339@2|Bacteria,1R4AJ@1224|Proteobacteria,2VP2M@28216|Betaproteobacteria,476SV@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Peptidase family M3	-	-	3.4.24.15	ko:K01392	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
TLS2_k127_2915324_0	983917.RGE_34730	0.0	1140.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2VH7P@28216|Betaproteobacteria,1KJHR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
TLS2_k127_2915336_0	397945.Aave_3439	1.428e-164	521.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2VIQT@28216|Betaproteobacteria,4A9NJ@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS2_k127_2915336_1	987059.RBXJA2T_16702	2.336e-158	508.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,2VHX0@28216|Betaproteobacteria,1KJJR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS2_k127_2915336_2	365046.Rta_11680	2.546e-34	136.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2VHM1@28216|Betaproteobacteria,4ABW8@80864|Comamonadaceae	28216|Betaproteobacteria	EQ	PFAM peptidase S58 DmpA	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
TLS2_k127_2917357_0	232721.Ajs_3976	5.71e-119	388.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2VHZJ@28216|Betaproteobacteria,4A9YT@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the GST superfamily	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_N
TLS2_k127_2917357_2	338969.Rfer_3836	1.647e-63	225.0	COG0607@1|root,COG0607@2|Bacteria,1RHQZ@1224|Proteobacteria,2VRMK@28216|Betaproteobacteria,4AEPK@80864|Comamonadaceae	28216|Betaproteobacteria	P	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS2_k127_2917357_3	232721.Ajs_3771	9.337e-51	190.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,2VTZE@28216|Betaproteobacteria,4AEE4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0225 family	ychJ	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
TLS2_k127_2917357_1	365044.Pnap_0467	2.094e-85	288.0	COG0637@1|root,COG0637@2|Bacteria,1NSPA@1224|Proteobacteria,2VH6V@28216|Betaproteobacteria,4A9WU@80864|Comamonadaceae	28216|Betaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
TLS2_k127_2941672_3	279714.FuraDRAFT_3753	1.123e-05	50.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2WB9J@28216|Betaproteobacteria,2KS4W@206351|Neisseriales	206351|Neisseriales	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
TLS2_k127_2941672_2	864051.BurJ1DRAFT_3408	7.632e-40	156.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,2VRMP@28216|Betaproteobacteria,1KKT5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS2_k127_2941672_0	1049564.TevJSym_ar00440	1.452e-95	324.0	COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,1RQQI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
TLS2_k127_2941672_1	1121116.KB894766_gene333	8.534e-70	239.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2VHFA@28216|Betaproteobacteria,4AAC9@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	GO:0003674,GO:0003824,GO:0004362,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0015949,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0022900,GO:0031974,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0055114,GO:0070013,GO:0070887,GO:0071704,GO:0097237,GO:0098754,GO:0098869,GO:1901360,GO:1990748	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS2_k127_2946062_1	987059.RBXJA2T_12914	4.308e-187	594.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,2VIR7@28216|Betaproteobacteria,1KJ2P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	lytic transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
TLS2_k127_2946062_3	864051.BurJ1DRAFT_1972	1.325e-66	231.0	COG3812@1|root,COG3812@2|Bacteria,1RGUV@1224|Proteobacteria,2VS54@28216|Betaproteobacteria,1KM4Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1993)	-	-	-	ko:K09983	-	-	-	-	ko00000	-	-	-	DUF1993
TLS2_k127_2946062_0	987059.RBXJA2T_12919	2.319e-189	595.0	COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,2VHIZ@28216|Betaproteobacteria,1KJI5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TLS2_k127_2946062_2	420662.Mpe_A1819	2.971e-129	440.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,2VITW@28216|Betaproteobacteria,1KJ4U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS2_k127_2946062_4	1286631.X805_41340	2.428e-60	214.0	COG2059@1|root,COG2059@2|Bacteria,1MZHQ@1224|Proteobacteria,2VQS5@28216|Betaproteobacteria,1KM4R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
TLS2_k127_2946062_5	864051.BurJ1DRAFT_1968	4.557e-51	193.0	COG2059@1|root,COG2059@2|Bacteria,1RAZW@1224|Proteobacteria,2VQ9R@28216|Betaproteobacteria,1KMC7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
TLS2_k127_2946062_6	1504672.669782980	5.224e-24	101.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2VHF4@28216|Betaproteobacteria,4AAVB@80864|Comamonadaceae	28216|Betaproteobacteria	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
TLS2_k127_2953074_0	1040989.AWZU01000028_gene3023	2.78e-246	776.0	COG0747@1|root,COG0747@2|Bacteria,1MUP8@1224|Proteobacteria,2TQXX@28211|Alphaproteobacteria,3JT8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	appA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
TLS2_k127_2953074_2	1207063.P24_14234	4.959e-156	497.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TSF3@28211|Alphaproteobacteria,2JV0Q@204441|Rhodospirillales	204441|Rhodospirillales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
TLS2_k127_2953074_3	1121861.KB899930_gene197	5.123e-134	433.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2TTEV@28211|Alphaproteobacteria,2JVNR@204441|Rhodospirillales	204441|Rhodospirillales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,OppC_N
TLS2_k127_2953074_1	1207063.P24_14244	5.029e-163	518.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,2JP9V@204441|Rhodospirillales	204441|Rhodospirillales	EP	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
TLS2_k127_2964253_2	987059.RBXJA2T_04033	1.9e-122	398.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria,1KJX0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Domain of unknown function (DUF3488)	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
TLS2_k127_2964253_1	987059.RBXJA2T_04038	2.236e-134	444.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,2VJGZ@28216|Betaproteobacteria,1KK54@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Lytic murein transglycosylase B	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
TLS2_k127_2964253_0	194867.ALBQ01000028_gene2375	4.512e-194	626.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,2TTR0@28211|Alphaproteobacteria,2K3IN@204457|Sphingomonadales	204457|Sphingomonadales	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
TLS2_k127_2968456_1	987059.RBXJA2T_19601	1.425e-113	381.0	28NZT@1|root,2ZBWJ@2|Bacteria,1RBSK@1224|Proteobacteria,2VQDC@28216|Betaproteobacteria,1KKKV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_2968456_0	983917.RGE_32460	1.046e-178	568.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2VHA7@28216|Betaproteobacteria,1KJXZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
TLS2_k127_2971629_3	1234364.AMSF01000034_gene288	6.172e-09	61.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X3KX@135614|Xanthomonadales	135614|Xanthomonadales	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
TLS2_k127_2971629_1	420662.Mpe_A0809	1.744e-171	544.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,2VI56@28216|Betaproteobacteria,1KKGG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	-	3.5.4.2	ko:K21053	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
TLS2_k127_2971629_0	983917.RGE_39430	0.0	1110.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2VHHQ@28216|Betaproteobacteria,1KJBE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS2_k127_2971629_2	614083.AWQR01000039_gene1484	5.403e-123	413.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2W0HF@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal
TLS2_k127_297812_3	1265502.KB905929_gene2272	6.295e-66	227.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria,4A9WC@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
TLS2_k127_297812_0	864051.BurJ1DRAFT_3938	1.729e-247	766.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2VHV3@28216|Betaproteobacteria,1KITB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS2_k127_297812_2	987059.RBXJA2T_00959	5.347e-127	411.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,1KJQR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
TLS2_k127_297812_1	983917.RGE_12560	7.856e-131	419.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2VHEQ@28216|Betaproteobacteria,1KIW6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
TLS2_k127_2988483_2	365046.Rta_06620	2.61e-61	212.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VJ7Q@28216|Betaproteobacteria,4AB7G@80864|Comamonadaceae	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS2_k127_2988483_1	983917.RGE_43430	2.121e-124	402.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2VI5G@28216|Betaproteobacteria,1KJZJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766,ko:K15312	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	ECH_1
TLS2_k127_2988483_0	398578.Daci_5970	1.356e-125	408.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2VH59@28216|Betaproteobacteria,4ABER@80864|Comamonadaceae	28216|Betaproteobacteria	I	Carbamoyl-phosphate synthase L chain, ATP-binding	accA1	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
TLS2_k127_2992322_10	864051.BurJ1DRAFT_3649	4.048e-12	67.0	2E3H4@1|root,32YFT@2|Bacteria,1N8PU@1224|Proteobacteria,2VVRT@28216|Betaproteobacteria,1KMMX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ZapB
TLS2_k127_2992322_8	987059.RBXJA2T_12557	3.274e-35	139.0	COG3027@1|root,COG3027@2|Bacteria,1PTHR@1224|Proteobacteria,2VTX2@28216|Betaproteobacteria,1KME5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
TLS2_k127_2992322_4	864051.BurJ1DRAFT_3652	1.425e-64	226.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2VRIB@28216|Betaproteobacteria,1KKX4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
TLS2_k127_2992322_1	864051.BurJ1DRAFT_3670	3.195e-97	326.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria,1KJBZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS2_k127_2992322_0	864051.BurJ1DRAFT_3671	4.696e-112	379.0	COG2199@1|root,COG2199@2|Bacteria,1R1VQ@1224|Proteobacteria,2VPRA@28216|Betaproteobacteria,1KKEC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4
TLS2_k127_2992322_3	864051.BurJ1DRAFT_3676	6.229e-79	276.0	COG0547@1|root,COG0547@2|Bacteria,1QJ8Q@1224|Proteobacteria,2VH2D@28216|Betaproteobacteria,1KIZH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Glycosyl transferase	trpD3	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
TLS2_k127_2992322_9	983917.RGE_15280	2.241e-34	134.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,2VTZ4@28216|Betaproteobacteria,1KM8X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
TLS2_k127_2992322_5	983917.RGE_15270	3.681e-63	220.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2VR35@28216|Betaproteobacteria,1KKU1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
TLS2_k127_2992322_7	864051.BurJ1DRAFT_3681	1.262e-46	177.0	COG3453@1|root,COG3453@2|Bacteria,1N9AF@1224|Proteobacteria,2VU0V@28216|Betaproteobacteria,1KMF5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
TLS2_k127_2992322_2	395495.Lcho_0975	1.45e-95	326.0	COG0297@1|root,COG0297@2|Bacteria,1QZYC@1224|Proteobacteria	1224|Proteobacteria	G	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS2_k127_2992322_6	1265502.KB905964_gene1391	4.219e-48	174.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2VHIP@28216|Betaproteobacteria,4AAKA@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
TLS2_k127_3006175_2	1123487.KB892834_gene2605	5.664e-30	124.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2VUBZ@28216|Betaproteobacteria,2KWWM@206389|Rhodocyclales	206389|Rhodocyclales	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
TLS2_k127_3006175_0	420662.Mpe_A2218	3.487e-136	441.0	COG2013@1|root,COG2013@2|Bacteria,1NBBE@1224|Proteobacteria,2VM49@28216|Betaproteobacteria,1KK9Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
TLS2_k127_3006175_1	864051.BurJ1DRAFT_1434	6.643e-127	428.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2VKXA@28216|Betaproteobacteria,1KJET@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
TLS2_k127_3008393_5	1379270.AUXF01000003_gene3533	5.469e-80	272.0	COG1009@1|root,COG1009@2|Bacteria,1ZUA7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
TLS2_k127_3008393_11	379066.GAU_2393	2.704e-31	126.0	COG0713@1|root,COG0713@2|Bacteria,1ZV1C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
TLS2_k127_3008393_10	379066.GAU_2394	2.207e-42	169.0	COG0839@1|root,COG0839@2|Bacteria,1ZUZB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
TLS2_k127_3008393_6	713587.THITH_10345	1.26e-79	279.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00338,ko:K02573	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
TLS2_k127_3008393_3	379066.GAU_2396	3.242e-179	571.0	COG1005@1|root,COG1005@2|Bacteria,1ZUSH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
TLS2_k127_3008393_1	713587.THITH_10355	1.538e-201	640.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1WWAH@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM NADH-quinone oxidoreductase, chain G	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,NADH-G_4Fe-4S_3
TLS2_k127_3008393_2	379066.GAU_2398	3.886e-199	637.0	COG1894@1|root,COG1894@2|Bacteria,1ZUDU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S
TLS2_k127_3008393_7	713587.THITH_10365	1.681e-64	227.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,1WWTG@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM NADH-quinone oxidoreductase, E subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
TLS2_k127_3008393_0	379066.GAU_2400	9.727e-212	664.0	COG0649@1|root,COG0649@2|Bacteria,1ZUHC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
TLS2_k127_3008393_8	1379270.AUXF01000003_gene3524	1.841e-60	221.0	COG0852@1|root,COG0852@2|Bacteria,1ZUVS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
TLS2_k127_3008393_4	1255043.TVNIR_1956	8.632e-92	303.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,1WW6I@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
TLS2_k127_3008393_9	713587.THITH_10385	9.64e-46	171.0	COG0838@1|root,COG0838@2|Bacteria	2|Bacteria	C	NADH dehydrogenase (ubiquinone) activity	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
TLS2_k127_3008393_12	1283300.ATXB01000002_gene2886	2.261e-24	108.0	COG3637@1|root,COG3637@2|Bacteria,1R42W@1224|Proteobacteria,1RYPE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative outer membrane beta-barrel porin, MtrB/PioB	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
TLS2_k127_3011650_1	864051.BurJ1DRAFT_1726	8.525e-105	344.0	COG0807@1|root,COG0807@2|Bacteria,1PQ5Y@1224|Proteobacteria,2VJ66@28216|Betaproteobacteria,1KJ1N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	GTP cyclohydrolase N terminal	ribA	-	-	-	-	-	-	-	-	-	-	-	GTP_CH_N,GTP_cyclohydro2
TLS2_k127_3011650_0	1500894.JQNN01000001_gene2776	6.653e-108	357.0	COG5285@1|root,COG5285@2|Bacteria,1Q78R@1224|Proteobacteria,2WAGD@28216|Betaproteobacteria,4756K@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	phyH	-	1.14.11.18	ko:K00477	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	PhyH
TLS2_k127_3011650_2	983917.RGE_45480	1.298e-87	294.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2W06E@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
TLS2_k127_3022593_4	983917.RGE_15170	7.303e-97	319.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,1KJ4K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
TLS2_k127_3022593_2	983917.RGE_15180	2.723e-110	362.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2VI2D@28216|Betaproteobacteria,1KKBY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
TLS2_k127_3022593_1	983917.RGE_15190	1.121e-134	434.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VH8C@28216|Betaproteobacteria,1KK2Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
TLS2_k127_3022593_5	864051.BurJ1DRAFT_3687	8.008e-97	322.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2VH28@28216|Betaproteobacteria,1KJPI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	molybdenum cofactor	mogA	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
TLS2_k127_3022593_6	987059.RBXJA2T_12497	6.649e-73	250.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,2VSGZ@28216|Betaproteobacteria,1KM7T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0307 family	yjgA	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
TLS2_k127_3022593_0	983917.RGE_15220	4.69e-230	719.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2VHJ4@28216|Betaproteobacteria,1KJ0J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
TLS2_k127_3022593_3	987059.RBXJA2T_10801	6.533e-106	349.0	COG0639@1|root,COG0639@2|Bacteria,1MUV1@1224|Proteobacteria,2VM0A@28216|Betaproteobacteria,1KK4M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
TLS2_k127_3029098_0	987059.RBXJA2T_03728	5.386e-270	840.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VJIJ@28216|Betaproteobacteria,1KKEV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
TLS2_k127_3029098_1	983917.RGE_29070	5.715e-247	767.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria,1KKCY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TLS2_k127_3029098_2	987059.RBXJA2T_03718	8.803e-225	706.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2VH1G@28216|Betaproteobacteria,1KIVA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
TLS2_k127_3043245_4	420662.Mpe_A1585	9.043e-66	227.0	COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,2VJFY@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS2_k127_3043245_3	420662.Mpe_A1583	6.475e-75	263.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,2VI3V@28216|Betaproteobacteria,1KPJI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC1	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
TLS2_k127_3043245_1	159087.Daro_2636	1.685e-182	576.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2VHWA@28216|Betaproteobacteria,2KUSU@206389|Rhodocyclales	28216|Betaproteobacteria	P	COG0798 Arsenite efflux pump ACR3 and related permeases	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
TLS2_k127_3043245_5	395495.Lcho_3121	1.944e-42	157.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2VTXZ@28216|Betaproteobacteria,1KMEI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
TLS2_k127_3043245_2	365044.Pnap_2844	2.72e-172	548.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,2VJC7@28216|Betaproteobacteria,4AH5M@80864|Comamonadaceae	28216|Betaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
TLS2_k127_3043245_7	365044.Pnap_2843	2.373e-30	128.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,2VWXC@28216|Betaproteobacteria,4AI5F@80864|Comamonadaceae	28216|Betaproteobacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
TLS2_k127_3043245_8	1366050.N234_08455	7.746e-23	100.0	COG3905@1|root,COG3905@2|Bacteria,1N7D2@1224|Proteobacteria,2VZ09@28216|Betaproteobacteria,1KDXV@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
TLS2_k127_3043245_0	296591.Bpro_0916	0.0	1154.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,2VMAN@28216|Betaproteobacteria,4ACA2@80864|Comamonadaceae	28216|Betaproteobacteria	C	Proton-conducting membrane transporter	hyfB	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
TLS2_k127_3043245_6	381666.H16_A2197	3.003e-41	175.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,2VKBD@28216|Betaproteobacteria,1K556@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NADH dehydrogenase	hyfD	-	-	-	-	-	-	-	-	-	-	-	NADHdh
TLS2_k127_3049113_0	1117647.M5M_06400	1.419e-47	191.0	COG0642@1|root,COG2205@2|Bacteria,1MXH7@1224|Proteobacteria,1RQZW@1236|Gammaproteobacteria,1J4RT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS2_k127_3053234_1	1265502.KB905948_gene978	9.907e-119	389.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VIPR@28216|Betaproteobacteria,4AA3P@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Cyclopropane-fatty-acyl-phospholipid synthase	mmaA3	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
TLS2_k127_3053234_0	864051.BurJ1DRAFT_4990	8.328e-145	466.0	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,2VIY0@28216|Betaproteobacteria,1KNNU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS2_k127_3053328_3	864051.BurJ1DRAFT_3841	1.778e-72	252.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,2VR81@28216|Betaproteobacteria,1KM34@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	YaeQ	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
TLS2_k127_3053328_0	987059.RBXJA2T_01550	0.0	1053.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2VHTT@28216|Betaproteobacteria,1KKFT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Prolyl oligopeptidase	f1pep1	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
TLS2_k127_3053328_2	983917.RGE_21460	1.642e-104	346.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,1KJE1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
TLS2_k127_3053328_1	420662.Mpe_A1468	1.939e-130	420.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,1KK3Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
TLS2_k127_3053328_4	1121106.JQKB01000019_gene2876	0.0001475	44.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS2_k127_3060692_3	983917.RGE_26410	3.772e-68	235.0	COG2267@1|root,COG2267@2|Bacteria,1R41P@1224|Proteobacteria,2VNV3@28216|Betaproteobacteria,1KNAN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
TLS2_k127_3060692_0	983917.RGE_33360	1.01e-127	412.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2VIND@28216|Betaproteobacteria,1KJMJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
TLS2_k127_3060692_1	983917.RGE_33350	7.012e-103	349.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,1KK61@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
TLS2_k127_3060692_2	987059.RBXJA2T_09632	2.043e-102	346.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2VINR@28216|Betaproteobacteria,1KITX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	DM	peptidase	nlpD	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
TLS2_k127_3070253_2	543728.Vapar_1010	2.434e-156	512.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2VNZH@28216|Betaproteobacteria,4AC1K@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Dehydrogenase, E1 component	bkdA1	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,OxoDH_E1alpha_N
TLS2_k127_3070253_1	983917.RGE_00880	5.378e-167	532.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2VIBJ@28216|Betaproteobacteria,1KK8B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	transcriptional regulator	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
TLS2_k127_3070253_0	987059.RBXJA2T_05233	0.0	1034.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,1KJNN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
TLS2_k127_3075159_1	637390.AFOH01000025_gene1036	1.285e-29	122.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,1SPE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
TLS2_k127_3075159_0	522306.CAP2UW1_3893	4.93e-262	823.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,2VJSI@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM SNF2-related protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
TLS2_k127_3084886_2	987059.RBXJA2T_06210	3.756e-134	437.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,1KK7C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	LU	TIGRFAM DNA protecting protein DprA	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
TLS2_k127_3084886_1	987059.RBXJA2T_06215	8.691e-160	518.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria,1KJD1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
TLS2_k127_3084886_5	864051.BurJ1DRAFT_4289	5.676e-77	262.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2VQ4N@28216|Betaproteobacteria,1KKJ5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
TLS2_k127_3084886_3	987059.RBXJA2T_06225	3.943e-131	425.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2VIS2@28216|Betaproteobacteria,1KKD5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
TLS2_k127_3084886_8	987059.RBXJA2T_06230	7.258e-30	125.0	2E6EI@1|root,33120@2|Bacteria,1NA6C@1224|Proteobacteria,2VW1M@28216|Betaproteobacteria,1KMDA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3084886_7	760117.JN27_15940	1.893e-36	150.0	COG3595@1|root,COG3595@2|Bacteria,1N8NB@1224|Proteobacteria,2W3BX@28216|Betaproteobacteria,47558@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
TLS2_k127_3084886_4	983917.RGE_04600	1.846e-91	310.0	COG1296@1|root,COG1296@2|Bacteria,1MVGN@1224|Proteobacteria,2VPFP@28216|Betaproteobacteria,1KKPF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	branched-chain amino acid permease (azaleucine resistance)	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
TLS2_k127_3084886_6	864051.BurJ1DRAFT_4294	6.759e-39	159.0	COG4392@1|root,COG4392@2|Bacteria,1N0X2@1224|Proteobacteria,2VTY9@28216|Betaproteobacteria,1KMAM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PFAM branched-chain amino acid transport	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
TLS2_k127_3084886_0	1031711.RSPO_c02792	3.44e-180	574.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2VHJK@28216|Betaproteobacteria,1K22I@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
TLS2_k127_3086375_0	365044.Pnap_0049	0.0	998.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,2VJ8P@28216|Betaproteobacteria,4AC24@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM aldehyde ferredoxin oxidoreductase	aorA	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
TLS2_k127_3086375_1	497321.C664_13434	1.936e-96	324.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2VKIS@28216|Betaproteobacteria,2KVRE@206389|Rhodocyclales	206389|Rhodocyclales	S	FAD-dependent pyridine	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
TLS2_k127_309402_1	319795.Dgeo_2507	1.161e-57	204.0	COG2103@1|root,COG2103@2|Bacteria,1WJPV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
TLS2_k127_309402_0	864051.BurJ1DRAFT_3442	7.006e-127	411.0	COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,2VHD8@28216|Betaproteobacteria,1KJ5F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	May be involved in recombination	rdgC	-	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
TLS2_k127_3118492_1	338969.Rfer_0280	3.86e-164	520.0	COG4638@1|root,COG4638@2|Bacteria,1MV2G@1224|Proteobacteria,2VI96@28216|Betaproteobacteria,4ABMV@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Rieske 2Fe-2S domain protein	vanA	-	1.14.12.7,1.14.13.82	ko:K03862,ko:K18068	ko00624,ko00627,ko01100,ko01120,ko01220,map00624,map00627,map01100,map01120,map01220	M00623	R03630,R05274	RC00392,RC00951,RC01533	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
TLS2_k127_3118492_2	1265502.KB905958_gene242	6.877e-52	194.0	COG1846@1|root,COG1846@2|Bacteria,1RJPG@1224|Proteobacteria,2VT4F@28216|Betaproteobacteria,4AEIR@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
TLS2_k127_3118492_0	365046.Rta_01300	1.112e-211	664.0	COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,2VK2M@28216|Betaproteobacteria,4AAN6@80864|Comamonadaceae	28216|Betaproteobacteria	O	AAA ATPase, central domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA
TLS2_k127_3137850_0	395495.Lcho_4305	1.126e-163	524.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,1KJ3Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein	iorB1	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
TLS2_k127_3137850_1	1286631.X805_39430	1.974e-82	277.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VQ9M@28216|Betaproteobacteria,1KKYN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	2Fe-2S -binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
TLS2_k127_3137850_2	1304872.JAGC01000005_gene1958	1.146e-06	56.0	COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,42PBT@68525|delta/epsilon subdivisions,2WMAY@28221|Deltaproteobacteria,2MA0Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	AraC-type transcriptional regulator N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
TLS2_k127_3143646_1	398578.Daci_5042	2.72e-115	375.0	COG0745@1|root,COG0745@2|Bacteria,1QUN8@1224|Proteobacteria,2VMWS@28216|Betaproteobacteria,4AG6K@80864|Comamonadaceae	28216|Betaproteobacteria	K	Two component transcriptional regulator	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS2_k127_3143646_0	358220.C380_22125	3.789e-206	676.0	COG0642@1|root,COG0642@2|Bacteria,1R6VZ@1224|Proteobacteria,2VPSF@28216|Betaproteobacteria,4AGEA@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
TLS2_k127_3143646_2	358220.C380_10020	1.941e-86	289.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2VR6Y@28216|Betaproteobacteria,4AC9T@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM OmpW family protein	ompW	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
TLS2_k127_3150973_2	556269.ACDQ01000017_gene825	5.029e-51	182.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2VIM1@28216|Betaproteobacteria,473RV@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS2_k127_3150973_4	1123377.AUIV01000007_gene1268	4.073e-40	151.0	COG3682@1|root,COG3682@2|Bacteria,1N6IF@1224|Proteobacteria,1T0R8@1236|Gammaproteobacteria,1XD1A@135614|Xanthomonadales	135614|Xanthomonadales	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
TLS2_k127_3150973_3	935567.JAES01000019_gene1028	8.288e-43	173.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,1R3YH@1224|Proteobacteria,1RX87@1236|Gammaproteobacteria,1X5U4@135614|Xanthomonadales	135614|Xanthomonadales	KT	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
TLS2_k127_3150973_5	887062.HGR_09820	2.417e-31	134.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VI49@28216|Betaproteobacteria,4ADU5@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS2_k127_3150973_0	305700.B447_18558	1.535e-266	853.0	COG4191@1|root,COG5001@1|root,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KUCK@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GAF,GGDEF,PAS,PAS_3,PAS_4,PAS_9
TLS2_k127_3150973_1	1157708.KB907481_gene1176	5.134e-120	397.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,4AAGH@80864|Comamonadaceae	28216|Betaproteobacteria	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
TLS2_k127_3182616_2	420662.Mpe_A1046	4.17e-80	275.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,1KIVR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
TLS2_k127_3182616_3	420662.Mpe_A1045	2.344e-76	261.0	COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2VK6A@28216|Betaproteobacteria,1KKUU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_11,TetR_N
TLS2_k127_3182616_1	987059.RBXJA2T_18358	3.664e-100	331.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2VJX3@28216|Betaproteobacteria,1KJSA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Ribosomal RNA adenine dimethylase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
TLS2_k127_3182616_0	420662.Mpe_A1041	9.807e-135	444.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,1KK6Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MU	TIGRFAM type I secretion outer membrane protein, TolC family	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
TLS2_k127_3186286_2	358220.C380_18550	2.342e-74	252.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,2VSFD@28216|Betaproteobacteria,4A9X0@80864|Comamonadaceae	28216|Betaproteobacteria	L	Belongs to the DnaA family	hda	-	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
TLS2_k127_3186286_1	365044.Pnap_2992	1.46e-94	316.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria,4AAAK@80864|Comamonadaceae	28216|Betaproteobacteria	E	HAD-superfamily hydrolase, subfamily IB, PSPase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD
TLS2_k127_3186286_0	543728.Vapar_1467	2.807e-233	734.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2VHY5@28216|Betaproteobacteria,4A9Z5@80864|Comamonadaceae	28216|Betaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
TLS2_k127_3186286_3	296591.Bpro_3560	6.622e-54	194.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2VSE2@28216|Betaproteobacteria,4AEGP@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
TLS2_k127_3193568_1	987059.RBXJA2T_00205	1.415e-51	189.0	COG2199@1|root,COG3706@2|Bacteria,1R6GI@1224|Proteobacteria,2VM5N@28216|Betaproteobacteria,1KJD2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
TLS2_k127_3193568_0	864051.BurJ1DRAFT_4235	0.0	1427.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,1KJ24@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Signal transducing histidine kinase, homodimeric domain	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
TLS2_k127_3202856_4	987059.RBXJA2T_14546	2.083e-54	198.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,2VIH0@28216|Betaproteobacteria,1KIWM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
TLS2_k127_3202856_2	987059.RBXJA2T_14541	2.163e-104	348.0	COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,2VN5G@28216|Betaproteobacteria,1KKA6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NT	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)	cheZ	-	-	ko:K03414	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheZ
TLS2_k127_3202856_3	864051.BurJ1DRAFT_0736	1.762e-69	239.0	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,2VR8X@28216|Betaproteobacteria,1KKZU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Response regulator receiver	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
TLS2_k127_3202856_1	987059.RBXJA2T_14531	5.112e-141	455.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,2VHMJ@28216|Betaproteobacteria,1KK2S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Membrane MotB of proton-channel complex MotA/MotB	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
TLS2_k127_3202856_0	864051.BurJ1DRAFT_0738	2.407e-156	499.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2VHPX@28216|Betaproteobacteria,1KJE3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	MotA/TolQ/ExbB proton channel family	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
TLS2_k127_3202856_5	983917.RGE_17050	1.31e-33	132.0	COG0500@1|root,COG0500@2|Bacteria,1QVCU@1224|Proteobacteria,2VP24@28216|Betaproteobacteria,1KKUB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3222427_5	987059.RBXJA2T_03001	1.515e-11	68.0	COG1160@1|root,COG1160@2|Bacteria,1QU8G@1224|Proteobacteria,2WGIU@28216|Betaproteobacteria,1KJ6T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF3482)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3482,MMR_HSR1
TLS2_k127_3222427_1	987059.RBXJA2T_03006	1.246e-228	715.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,2VIH1@28216|Betaproteobacteria,1KITP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	TrkA-C domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
TLS2_k127_3222427_2	1286631.X805_07550	5e-212	678.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2VH82@28216|Betaproteobacteria,1KKB8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
TLS2_k127_3222427_0	983917.RGE_43450	1.265e-309	954.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VI77@28216|Betaproteobacteria,1KJ65@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Carboxyl transferase domain	accB	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
TLS2_k127_3222427_4	426114.THI_3273	1.333e-16	83.0	COG5450@1|root,COG5450@2|Bacteria,1N76R@1224|Proteobacteria,2VWE3@28216|Betaproteobacteria,1KMHH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
TLS2_k127_3222427_3	1123504.JQKD01000002_gene3713	1.026e-48	178.0	COG1487@1|root,COG1487@2|Bacteria,1RHIX@1224|Proteobacteria,2VRES@28216|Betaproteobacteria,4AG0K@80864|Comamonadaceae	28216|Betaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
TLS2_k127_3228887_0	983917.RGE_46060	2.141e-201	635.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,1KIVB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Belongs to the methyltransferase superfamily	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
TLS2_k127_3228887_1	987059.RBXJA2T_13259	7.925e-196	618.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria,1KJHW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
TLS2_k127_3240992_0	1123261.AXDW01000003_gene2003	3.267e-210	670.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RZ70@1236|Gammaproteobacteria,1X4ZJ@135614|Xanthomonadales	135614|Xanthomonadales	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61,TPR_3
TLS2_k127_3244929_3	614083.AWQR01000031_gene2665	1.073e-84	282.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VR4P@28216|Betaproteobacteria,4AB5N@80864|Comamonadaceae	28216|Betaproteobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
TLS2_k127_3244929_1	983917.RGE_32630	3.288e-305	943.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,1KJEJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Large family of predicted nucleotide-binding domains	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
TLS2_k127_3244929_4	1144319.PMI16_02675	5.602e-66	229.0	COG0454@1|root,COG0454@2|Bacteria,1QUHE@1224|Proteobacteria	1224|Proteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	ysnE	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
TLS2_k127_3244929_0	987059.RBXJA2T_12202	0.0	1090.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VI3T@28216|Betaproteobacteria,1KKBU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Acetyl-coenzyme A synthetase N-terminus	prpE	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
TLS2_k127_3244929_2	983917.RGE_32660	3.244e-159	507.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria,1KJ5W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	alcohol dehydrogenase	-	-	-	ko:K19745	ko00640,ko01100,map00640,map01100	-	R00919	RC00095	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS2_k127_3244929_6	864051.BurJ1DRAFT_2485	4.435e-11	67.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,1KK5U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
TLS2_k127_3252273_3	987059.RBXJA2T_09869	3.263e-24	102.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VIT2@28216|Betaproteobacteria,1KK96@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Methylmalonyl-CoA mutase	icmF	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
TLS2_k127_3252273_2	477184.KYC_22701	1.156e-35	147.0	COG0346@1|root,COG0454@1|root,COG0346@2|Bacteria,COG0456@2|Bacteria,1RH4C@1224|Proteobacteria,2WFSG@28216|Betaproteobacteria,3T7NM@506|Alcaligenaceae	28216|Betaproteobacteria	EK	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,Glyoxalase
TLS2_k127_3252273_4	1463845.JOIG01000004_gene4611	2.921e-12	77.0	COG3631@1|root,COG3631@2|Bacteria,2IM60@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
TLS2_k127_3252273_0	987059.RBXJA2T_09864	7.091e-147	484.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2VIRF@28216|Betaproteobacteria,1KJBP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
TLS2_k127_3252273_1	420662.Mpe_A1016	3.814e-73	247.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VIYF@28216|Betaproteobacteria,1KK87@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Carboxyl transferase domain	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
TLS2_k127_3253243_5	270374.MELB17_17814	1.698e-33	130.0	COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,1RPU1@1236|Gammaproteobacteria,464YM@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
TLS2_k127_3253243_1	344747.PM8797T_12006	4.225e-149	483.0	COG4658@1|root,COG4658@2|Bacteria,2IY8E@203682|Planctomycetes	203682|Planctomycetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	-	-	-	-	-	-	-	-	-	-	NQR2_RnfD_RnfE
TLS2_k127_3253243_4	1443113.LC20_01281	1.625e-64	230.0	COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,1RR85@1236|Gammaproteobacteria,41FB6@629|Yersinia	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
TLS2_k127_3253243_2	745411.B3C1_11047	1.555e-82	282.0	COG1347@1|root,COG1347@2|Bacteria,1MUZR@1224|Proteobacteria,1RNFE@1236|Gammaproteobacteria,1J4TB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
TLS2_k127_3253243_3	1121918.ARWE01000001_gene1330	4.021e-78	276.0	COG2209@1|root,COG2209@2|Bacteria,1R33S@1224|Proteobacteria	1224|Proteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
TLS2_k127_3253243_0	391625.PPSIR1_12038	1.916e-157	503.0	COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,42MXC@68525|delta/epsilon subdivisions,2WJJF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
TLS2_k127_3255558_4	379731.PST_3284	4.263e-65	233.0	2CH0A@1|root,2ZANK@2|Bacteria,1R6U4@1224|Proteobacteria,1RQ3J@1236|Gammaproteobacteria,1YZXP@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3255558_3	1384056.N787_12100	7.562e-82	287.0	COG0457@1|root,COG0457@2|Bacteria,1MUTV@1224|Proteobacteria,1SYSA@1236|Gammaproteobacteria,1X61P@135614|Xanthomonadales	135614|Xanthomonadales	E	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8,Transglut_core
TLS2_k127_3255558_2	983917.RGE_14190	5.48e-106	348.0	COG4340@1|root,COG4340@2|Bacteria,1R9YQ@1224|Proteobacteria,2VHC5@28216|Betaproteobacteria,1KJ3W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	2OG-Fe dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-Fe_Oxy_2
TLS2_k127_3255558_0	859657.RPSI07_mp1534	1.899e-139	452.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VJM2@28216|Betaproteobacteria,1K3CW@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS2_k127_3255558_1	987059.RBXJA2T_16762	3.294e-106	350.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,2VK5M@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM peptidase S10 serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
TLS2_k127_3259981_1	983917.RGE_45900	3.364e-138	442.0	COG0121@1|root,COG0121@2|Bacteria,1MU1J@1224|Proteobacteria,2VJP1@28216|Betaproteobacteria,1KKGS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Glutamine amido-transferase	yafJ	-	-	-	-	-	-	-	-	-	-	-	GATase_4
TLS2_k127_3259981_3	1100720.ALKN01000030_gene1018	2.346e-31	135.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ6F@28216|Betaproteobacteria,4ADGN@80864|Comamonadaceae	28216|Betaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
TLS2_k127_3259981_0	983917.RGE_45910	2.488e-173	552.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,2VTTR@28216|Betaproteobacteria,1KIVH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Tryptophan halogenase	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
TLS2_k127_3259981_2	983917.RGE_46140	2.854e-127	411.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2VJZN@28216|Betaproteobacteria,1KJ4C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
TLS2_k127_33003_0	1458275.AZ34_11585	6.928e-209	655.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,4AAY8@80864|Comamonadaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS2_k127_33003_1	887062.HGR_04798	2.382e-117	389.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,2VIDH@28216|Betaproteobacteria,4AAUQ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS2_k127_33003_2	397945.Aave_4662	3.265e-77	270.0	COG1538@1|root,COG1538@2|Bacteria,1P0S2@1224|Proteobacteria,2VH06@28216|Betaproteobacteria,4AAJB@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family	tolC2	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS2_k127_3304353_3	1353528.DT23_14360	1.554e-05	50.0	COG1595@1|root,COG1595@2|Bacteria,1RI7C@1224|Proteobacteria	1224|Proteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS2_k127_3304353_2	1437824.BN940_06866	4.162e-36	141.0	COG0421@1|root,COG1586@1|root,COG0421@2|Bacteria,COG1586@2|Bacteria,1MVV5@1224|Proteobacteria,2WGFP@28216|Betaproteobacteria,3T9I0@506|Alcaligenaceae	28216|Betaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Spermine_synt_N,Spermine_synth
TLS2_k127_3304353_0	983917.RGE_44770	0.0	1097.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,1KJAJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
TLS2_k127_3304353_1	522306.CAP2UW1_0822	2.478e-190	599.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,1KQ7J@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
TLS2_k127_3308083_3	983917.RGE_04940	1.029e-30	133.0	COG3070@1|root,COG3070@2|Bacteria,1N8X8@1224|Proteobacteria,2VVUD@28216|Betaproteobacteria,1KMNK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	TfoX N-terminal domain	tfoX	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
TLS2_k127_3308083_1	983917.RGE_04950	1.042e-95	320.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2VJZE@28216|Betaproteobacteria,1KK6Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	5-formyltetrahydrofolate cyclo-ligase	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
TLS2_k127_3308083_2	983917.RGE_04970	5.648e-60	214.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2VR6Y@28216|Betaproteobacteria,1KKWE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	OmpW family	ompW	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
TLS2_k127_3308083_0	983917.RGE_04980	6.506e-118	380.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2VHHI@28216|Betaproteobacteria,1KJJJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Methylenetetrahydrofolate reductase	metF	GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
TLS2_k127_3312806_2	296591.Bpro_1055	2.817e-137	445.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2VICE@28216|Betaproteobacteria,4ABG9@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM NUDIX hydrolase	-	-	-	ko:K07455	-	-	-	-	ko00000,ko03400	-	-	-	Lactamase_B,NUDIX
TLS2_k127_3312806_1	365046.Rta_33500	1.641e-168	563.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2VH8D@28216|Betaproteobacteria,4AAEI@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS2_k127_3312806_0	296591.Bpro_1279	2.439e-175	562.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,4AABQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS2_k127_3312806_3	358220.C380_19170	1.232e-13	73.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2VHK7@28216|Betaproteobacteria,4A9JP@80864|Comamonadaceae	28216|Betaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
TLS2_k127_3315789_2	864051.BurJ1DRAFT_2260	3.615e-79	274.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,2VRIQ@28216|Betaproteobacteria,1KKPU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
TLS2_k127_3315789_1	987059.RBXJA2T_08980	1.413e-106	357.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,2VI54@28216|Betaproteobacteria,1KIVG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	ATPases associated with a variety of cellular activities	lolD	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS2_k127_3315789_0	358220.C380_10040	2.338e-160	512.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,4A9PT@80864|Comamonadaceae	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpF	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
TLS2_k127_3316383_5	983917.RGE_41430	3.882e-82	276.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2VI50@28216|Betaproteobacteria,1KJ20@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
TLS2_k127_3316383_1	987059.RBXJA2T_06645	2.901e-165	522.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2VHA6@28216|Betaproteobacteria,1KK1J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TLS2_k127_3316383_4	864051.BurJ1DRAFT_1286	8.994e-87	299.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2VQ02@28216|Betaproteobacteria,1KKY5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
TLS2_k127_3316383_7	864051.BurJ1DRAFT_3809	9.858e-28	114.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,1KMII@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Cold shock protein	cspD	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
TLS2_k127_3316383_3	864051.BurJ1DRAFT_1264	2.787e-103	344.0	COG0760@1|root,COG0760@2|Bacteria,1R4EF@1224|Proteobacteria,2VK6Z@28216|Betaproteobacteria,1KITZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2,SurA_N_2,SurA_N_3
TLS2_k127_3316383_2	987059.RBXJA2T_07050	8.78e-123	402.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2VHBM@28216|Betaproteobacteria,1KIZW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
TLS2_k127_3316383_6	420662.Mpe_A2736	1.706e-63	222.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,1KM1S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
TLS2_k127_3316383_0	887062.HGR_08554	1.982e-272	843.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,4A9NT@80864|Comamonadaceae	28216|Betaproteobacteria	C	FAD linked oxidase domain protein	glpCD	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
TLS2_k127_3327967_0	983917.RGE_10210	1.949e-270	839.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,1KJPZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
TLS2_k127_3327967_3	1265502.KB905949_gene974	1.498e-29	121.0	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,2VVQK@28216|Betaproteobacteria,4AEZK@80864|Comamonadaceae	28216|Betaproteobacteria	KL	Belongs to the transcriptional regulatory Fis family	fis	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
TLS2_k127_3327967_1	983917.RGE_10230	9.47e-164	524.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,1KJF9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
TLS2_k127_3327967_2	864051.BurJ1DRAFT_1202	1.302e-72	249.0	COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,2VUM5@28216|Betaproteobacteria,1KKMY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	SNARE associated Golgi protein	yqaA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
TLS2_k127_3327967_4	983917.RGE_10250	8.472e-24	111.0	COG2317@1|root,COG2317@2|Bacteria,1MW7T@1224|Proteobacteria,2VKEK@28216|Betaproteobacteria,1KKE6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	ctaQ	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
TLS2_k127_3328830_0	62928.azo1149	0.0	1022.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VH3P@28216|Betaproteobacteria,2KVZ5@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
TLS2_k127_3328830_2	85643.Tmz1t_1262	5.218e-37	146.0	COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,2VUFA@28216|Betaproteobacteria,2KX0Q@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
TLS2_k127_3328830_5	159450.NH14_17890	1.933e-06	52.0	COG1295@1|root,COG1295@2|Bacteria,1R9UY@1224|Proteobacteria,2VJV0@28216|Betaproteobacteria,1K3VN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
TLS2_k127_3328830_1	640512.BC1003_4839	2.89e-69	238.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,1K518@119060|Burkholderiaceae	28216|Betaproteobacteria	K	regulator	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
TLS2_k127_3328830_4	1538295.JY96_19445	1.394e-09	62.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,1KM2G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Bacterial regulatory proteins, luxR family	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
TLS2_k127_3328830_3	640512.BC1003_4840	2.32e-12	67.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,1K2VF@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	narX	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
TLS2_k127_3336635_0	864051.BurJ1DRAFT_3131	8.726e-239	745.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VJ6T@28216|Betaproteobacteria,1KJDG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3501
TLS2_k127_3336635_1	395495.Lcho_2672	7.583e-77	276.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,2VQUX@28216|Betaproteobacteria,1KJPT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
TLS2_k127_3336635_2	987059.RBXJA2T_14826	1.355e-41	158.0	COG4989@1|root,COG4989@2|Bacteria,1MY3G@1224|Proteobacteria,2VKGY@28216|Betaproteobacteria,1KKVM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Aldo/keto reductase family	ydhF	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS2_k127_3343881_3	987059.RBXJA2T_15558	4.912e-24	104.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2VH21@28216|Betaproteobacteria,1KK6R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	TIGRFAM A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
TLS2_k127_3343881_1	987059.RBXJA2T_15563	2.671e-76	261.0	COG2802@1|root,COG2802@2|Bacteria,1RFYH@1224|Proteobacteria,2VSA4@28216|Betaproteobacteria,1KKT9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
TLS2_k127_3343881_0	983917.RGE_08790	3.078e-142	456.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2VIH5@28216|Betaproteobacteria,1KIT5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Displays ATPase and GTPase activities	yhbJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
TLS2_k127_3343881_2	987059.RBXJA2T_15573	1.918e-47	174.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,1KK5K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
TLS2_k127_3382698_1	232721.Ajs_2020	9.295e-137	462.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,2VIWW@28216|Betaproteobacteria,4AAIX@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix-turn-helix- domain containing protein, AraC type	ada	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
TLS2_k127_3382698_0	365044.Pnap_1108	1.164e-182	575.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,4ABAF@80864|Comamonadaceae	28216|Betaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	algC	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TLS2_k127_3401380_0	987059.RBXJA2T_06660	3.026e-288	897.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2VHGF@28216|Betaproteobacteria,1KKC5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	GM	Polysaccharide biosynthesis protein	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
TLS2_k127_3401380_1	1123377.AUIV01000012_gene721	4.625e-134	438.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RRXR@1236|Gammaproteobacteria,1XAEU@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
TLS2_k127_3401380_2	987059.RBXJA2T_06665	3.072e-87	292.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2VQBN@28216|Betaproteobacteria,1KKM2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Sugar transferase	bplG	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
TLS2_k127_340392_0	420662.Mpe_A1585	1.038e-138	453.0	COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,2VJFY@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS2_k127_340392_1	1121033.AUCF01000033_gene3621	4.725e-135	441.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2TU32@28211|Alphaproteobacteria,2JQWP@204441|Rhodospirillales	204441|Rhodospirillales	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
TLS2_k127_340392_3	420662.Mpe_B0048	7.627e-34	136.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2VU86@28216|Betaproteobacteria,1KMMJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KT	Peptidase S24-like	-	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
TLS2_k127_340392_2	1268622.AVS7_02332	1.487e-35	139.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2VHHK@28216|Betaproteobacteria,4AB3P@80864|Comamonadaceae	28216|Betaproteobacteria	L	Domain of unknown function (DUF4113)	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
TLS2_k127_3405870_2	983917.RGE_37600	1.216e-112	376.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VI20@28216|Betaproteobacteria,1KIVM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ABC-type Fe3 transport system, permease component	fbpB	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
TLS2_k127_3405870_1	420662.Mpe_A1085	1.15e-170	546.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHGM@28216|Betaproteobacteria,1KJ77@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
TLS2_k127_3405870_4	426114.THI_2267	0.0001527	46.0	COG1587@1|root,COG1587@2|Bacteria	2|Bacteria	H	uroporphyrinogen-III synthase activity	hemD	GO:0003674,GO:0003824,GO:0004852,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.107,2.5.1.61,4.2.1.75	ko:K01719,ko:K01749,ko:K02496,ko:K13542,ko:K13543	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084,R03165,R03194	RC00003,RC00871,RC01861,RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0187,iSBO_1134.SBO_3815	HEM4,HemX
TLS2_k127_3405870_3	1131553.JIBI01000043_gene1917	5.727e-101	339.0	COG0412@1|root,COG0412@2|Bacteria,1R3DI@1224|Proteobacteria,2VUJ3@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
TLS2_k127_3405870_0	987059.RBXJA2T_17721	4.13e-205	640.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2VHVY@28216|Betaproteobacteria,1KJ3T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
TLS2_k127_3445561_1	987059.RBXJA2T_02936	7.012e-176	560.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria,1KJ0S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
TLS2_k127_3445561_0	420662.Mpe_A1471	8.219e-262	824.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria,1KJ7X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
TLS2_k127_3445561_2	1458275.AZ34_01020	1.601e-22	100.0	COG1918@1|root,COG1918@2|Bacteria,1NASN@1224|Proteobacteria,2VVSY@28216|Betaproteobacteria,4AFGG@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM FeoA family protein	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
TLS2_k127_3466197_0	983917.RGE_26970	0.0	2041.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,1KJBK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	TIGRFAM ATP-dependent helicase HrpA	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
TLS2_k127_3466197_1	864051.BurJ1DRAFT_2641	1.837e-47	184.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2VK1F@28216|Betaproteobacteria,1KPKD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
TLS2_k127_3469172_4	338969.Rfer_2850	7.436e-59	214.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,2VJ8P@28216|Betaproteobacteria,4AC24@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM aldehyde ferredoxin oxidoreductase	aorA	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
TLS2_k127_3469172_1	365044.Pnap_0048	2.18e-100	328.0	COG1142@1|root,COG1142@2|Bacteria,1MWE1@1224|Proteobacteria,2VJ9U@28216|Betaproteobacteria,4AC5H@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K05796	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_11,Fer4_4,Fer4_6,Fer4_9
TLS2_k127_3469172_2	666685.R2APBS1_2671	1.108e-90	310.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,1X44M@135614|Xanthomonadales	135614|Xanthomonadales	M	phospholipase	pldA	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
TLS2_k127_3469172_0	395495.Lcho_3216	2.781e-124	419.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,1KISZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	chemotaxis sensory transducer	-	-	-	ko:K03406,ko:K03776,ko:K05874	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS,PAS_3,PAS_8,TarH,sCache_2
TLS2_k127_3469172_3	983917.RGE_39400	2.314e-70	243.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2VR41@28216|Betaproteobacteria,1KKXY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NT	Two component signalling adaptor domain	cheW-1	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
TLS2_k127_3480524_4	1121920.AUAU01000010_gene126	2.097e-33	133.0	28PU4@1|root,2ZCF6@2|Bacteria	2|Bacteria	-	-	nrfJ	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3480524_1	543728.Vapar_3754	1.058e-73	254.0	COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,2VRAN@28216|Betaproteobacteria,4AJDI@80864|Comamonadaceae	28216|Betaproteobacteria	M	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
TLS2_k127_3480524_0	596154.Alide2_0733	8.333e-224	706.0	COG1075@1|root,COG1075@2|Bacteria,1MXMP@1224|Proteobacteria,2VMFJ@28216|Betaproteobacteria,4AGE8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PGAP1
TLS2_k127_3480524_3	983917.RGE_11510	3.047e-40	158.0	COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,2VUGY@28216|Betaproteobacteria,1KPK3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF454)	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
TLS2_k127_3480524_7	1121878.AUGL01000028_gene2068	0.0001056	49.0	2EQBK@1|root,33HXQ@2|Bacteria,1NJKS@1224|Proteobacteria,1SW7A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3480524_5	1121878.AUGL01000001_gene309	3.941e-33	133.0	2E4R1@1|root,32ZJK@2|Bacteria,1N8FZ@1224|Proteobacteria,1S42H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Nitrous oxide-stimulated promoter	ygbA	-	-	-	-	-	-	-	-	-	-	-	YgbA_NO
TLS2_k127_3480524_2	1198452.Jab_1c15290	4.814e-45	168.0	COG4564@1|root,COG4564@2|Bacteria,1RFW5@1224|Proteobacteria,2VTWN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	sCache_2
TLS2_k127_3506606_0	595537.Varpa_5865	2.677e-261	811.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VHP1@28216|Betaproteobacteria,4AAN4@80864|Comamonadaceae	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE1	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_C,Transketolase_N
TLS2_k127_3506606_1	864051.BurJ1DRAFT_3359	1.252e-90	312.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,2VKYM@28216|Betaproteobacteria,1KKQN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	apbA	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
TLS2_k127_3506606_4	596154.Alide2_1212	1.139e-17	87.0	COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,2VW0H@28216|Betaproteobacteria,4AFDE@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM SlyX family protein	slyX	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
TLS2_k127_3506606_3	1538295.JY96_08785	7.922e-42	158.0	2E0NI@1|root,32W7K@2|Bacteria,1N1F0@1224|Proteobacteria,2VUBC@28216|Betaproteobacteria,1KMEX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3506606_2	365044.Pnap_1532	1.163e-45	170.0	COG2010@1|root,COG2010@2|Bacteria,1N1Z3@1224|Proteobacteria,2VU18@28216|Betaproteobacteria,4AF6R@80864|Comamonadaceae	28216|Betaproteobacteria	C	Domain of unknown function (DUF1924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1924
TLS2_k127_3506606_5	1538295.JY96_14980	1.398e-12	71.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria,1KM3I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
TLS2_k127_3506735_4	365046.Rta_33400	1.644e-46	174.0	COG2267@1|root,COG2267@2|Bacteria,1QUZX@1224|Proteobacteria,2VQK8@28216|Betaproteobacteria,4ADMB@80864|Comamonadaceae	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
TLS2_k127_3506735_1	983917.RGE_24180	9.11e-88	308.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,2VSX2@28216|Betaproteobacteria,1KMKV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS2_k127_3506735_3	1279038.KB907338_gene1110	8.872e-68	234.0	COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,2U78G@28211|Alphaproteobacteria,2JSSF@204441|Rhodospirillales	204441|Rhodospirillales	S	dioxygenase of extradiol dioxygenase family	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS2_k127_3506735_2	987059.RBXJA2T_13364	4.521e-75	259.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2VS5A@28216|Betaproteobacteria,1KKX9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
TLS2_k127_3506735_0	1123255.JHYS01000019_gene1726	1.035e-141	455.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2VKA4@28216|Betaproteobacteria,4AC1M@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
TLS2_k127_3522554_1	999541.bgla_1g36090	9.849e-81	271.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,1K0HN@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Vitamin B12 dependent methionine synthase activation region	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
TLS2_k127_3522554_0	864051.BurJ1DRAFT_4548	9.078e-271	839.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH8M@28216|Betaproteobacteria,1KIZS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	glcD	-	1.1.2.4,1.1.3.15,1.1.5.12	ko:K00102,ko:K00104,ko:K03777	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475,R00704,R11591	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
TLS2_k127_3522554_2	1265502.KB905968_gene1257	6.399e-50	179.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2VHUQ@28216|Betaproteobacteria,4AAAA@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
TLS2_k127_3528342_8	395495.Lcho_3605	3.32e-20	104.0	COG0001@1|root,COG0001@2|Bacteria,1QVPQ@1224|Proteobacteria,2WHQE@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS2_k127_3528342_2	395495.Lcho_3604	2.081e-116	382.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,2VH0R@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Phosphatidylserine decarboxylase	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
TLS2_k127_3528342_1	1265502.KB905933_gene2035	4.908e-137	446.0	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,2VHU3@28216|Betaproteobacteria,4ACS8@80864|Comamonadaceae	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
TLS2_k127_3528342_0	983917.RGE_31520	1.184e-248	785.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,2VI53@28216|Betaproteobacteria,1KN8N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	yjcC	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
TLS2_k127_3528342_5	663610.JQKO01000016_gene1565	6.296e-72	247.0	COG1309@1|root,COG1309@2|Bacteria,1RDIP@1224|Proteobacteria,2U7DV@28211|Alphaproteobacteria,3NBU6@45404|Beijerinckiaceae	28211|Alphaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS2_k127_3528342_7	663610.JQKO01000016_gene1566	1.465e-61	214.0	COG3370@1|root,COG3370@2|Bacteria,1Q6VY@1224|Proteobacteria,2USDT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
TLS2_k127_3528342_4	1183438.GKIL_3589	1.17e-73	259.0	COG3576@1|root,COG3576@2|Bacteria,1G2UH@1117|Cyanobacteria	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
TLS2_k127_3528342_6	883126.HMPREF9710_02640	3.864e-67	239.0	COG1018@1|root,COG1018@2|Bacteria,1MU6E@1224|Proteobacteria,2W949@28216|Betaproteobacteria,477N5@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
TLS2_k127_3528342_3	420662.Mpe_A3316	2.355e-81	275.0	COG3576@1|root,COG3576@2|Bacteria,1NBWC@1224|Proteobacteria,2VKQ8@28216|Betaproteobacteria,1KNUM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase-related, FMN binding protein	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
TLS2_k127_3542936_5	243233.MCA1693	1.691e-39	165.0	COG2913@1|root,COG2913@2|Bacteria,1RDAX@1224|Proteobacteria,1SIDU@1236|Gammaproteobacteria,1XH0J@135618|Methylococcales	135618|Methylococcales	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3542936_0	1265502.KB905930_gene1541	1.87e-164	524.0	COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,2VHCA@28216|Betaproteobacteria,4A9MT@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
TLS2_k127_3542936_2	983917.RGE_26380	2.966e-143	460.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2VJQQ@28216|Betaproteobacteria,1KN99@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772,ko:K03815	ko00230,ko00270,ko01100,ko01110,map00230,map00270,map01100,map01110	M00034	R01402,R02297	RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
TLS2_k127_3542936_1	983917.RGE_26370	3.77e-159	511.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,2VI2X@28216|Betaproteobacteria,1KNB2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
TLS2_k127_3542936_4	987059.RBXJA2T_08660	2.369e-81	287.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,2VQBC@28216|Betaproteobacteria,1KNPC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
TLS2_k127_3542936_3	983917.RGE_26340	7.064e-126	410.0	COG0697@1|root,COG0697@2|Bacteria,1PX5W@1224|Proteobacteria,2VJ2A@28216|Betaproteobacteria,1KK3P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS2_k127_3542936_6	987059.RBXJA2T_08640	1.884e-21	93.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria,1KJBV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Aldehyde dehydrogenase family	puuC	-	1.2.1.54,1.2.1.8,1.2.1.99	ko:K00130,ko:K09472,ko:K12254	ko00260,ko00330,ko01100,map00260,map00330,map01100	M00136,M00555	R02549,R02565,R02566,R03177,R07417,R07418	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS2_k127_3550321_2	1157708.KB907453_gene4140	1.366e-103	349.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2VN2I@28216|Betaproteobacteria,4AD1D@80864|Comamonadaceae	28216|Betaproteobacteria	E	peptidase dimerisation domain protein	cgp	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
TLS2_k127_3550321_0	497321.C664_17110	1.402e-281	879.0	COG4670@1|root,COG4670@2|Bacteria,1MUJW@1224|Proteobacteria,2VH8B@28216|Betaproteobacteria,2KVP5@206389|Rhodocyclales	206389|Rhodocyclales	I	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons	-	-	2.8.3.1	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	-	R00928,R01449,R05508	RC00012,RC00014,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
TLS2_k127_3550321_1	1538295.JY96_01930	6.519e-121	389.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,1KKA3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
TLS2_k127_3550321_3	987059.RBXJA2T_17509	1.488e-18	87.0	COG4539@1|root,COG4539@2|Bacteria,1RHUB@1224|Proteobacteria,2VTDF@28216|Betaproteobacteria,1KM7Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
TLS2_k127_3552710_0	864051.BurJ1DRAFT_2640	3.024e-121	391.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VI90@28216|Betaproteobacteria,1KK6J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Iron-containing alcohol dehydrogenase	gbd1	-	1.1.1.61,1.3.1.32	ko:K00043,ko:K00217	ko00361,ko00362,ko00364,ko00623,ko00650,ko01100,ko01120,ko01200,ko01220,map00361,map00362,map00364,map00623,map00650,map01100,map01120,map01200,map01220	-	R01644,R02988,R02989,R05355,R06848,R07781,R09137,R09138,R09223,R09224	RC00087,RC00107,RC01335,RC01689,RC02442	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
TLS2_k127_3552710_2	331869.BAL199_15643	7.6e-46	179.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,2U5SV@28211|Alphaproteobacteria,4BSBP@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Endoribonuclease L-PSP	MA20_29855	-	-	ko:K09021	ko00240,ko01100,map00240,map01100	-	R09982	RC02768	ko00000,ko00001	-	-	-	Ribonuc_L-PSP
TLS2_k127_3552710_3	1384054.N790_04835	1.13e-31	128.0	COG1725@1|root,COG1725@2|Bacteria,1MZG9@1224|Proteobacteria,1S993@1236|Gammaproteobacteria,1X6MY@135614|Xanthomonadales	135614|Xanthomonadales	K	GntR family transcriptional regulator	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
TLS2_k127_3552710_1	1121015.N789_01205	9.054e-82	282.0	COG1131@1|root,COG1131@2|Bacteria,1R3XF@1224|Proteobacteria,1S0MM@1236|Gammaproteobacteria,1X3B4@135614|Xanthomonadales	135614|Xanthomonadales	V	abc transporter atp-binding protein	nodI	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS2_k127_3552710_4	1123253.AUBD01000001_gene1706	1.058e-08	66.0	2E7DT@1|root,331WV@2|Bacteria,1N62R@1224|Proteobacteria,1SB2G@1236|Gammaproteobacteria,1X5G8@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_5
TLS2_k127_3552883_1	1120999.JONM01000007_gene1768	1.064e-126	414.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,2KPQ3@206351|Neisseriales	206351|Neisseriales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07788	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
TLS2_k127_3552883_0	1120999.JONM01000007_gene1769	0.0	1249.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,2KPSG@206351|Neisseriales	206351|Neisseriales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07789	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
TLS2_k127_3552883_2	1144342.PMI40_03174	1.036e-47	190.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VISZ@28216|Betaproteobacteria,4736U@75682|Oxalobacteraceae	28216|Betaproteobacteria	MU	Outer membrane efflux protein	nodT	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS2_k127_3553125_2	946483.Cenrod_0845	2.083e-63	224.0	COG0834@1|root,COG0834@2|Bacteria,1N0VS@1224|Proteobacteria,2VXE3@28216|Betaproteobacteria	28216|Betaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
TLS2_k127_3553125_1	1211115.ALIQ01000185_gene3145	7.746e-140	450.0	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,2TUCW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	ddpC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
TLS2_k127_3553125_0	365044.Pnap_3830	1.196e-169	539.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VNVT@28216|Betaproteobacteria,4AGCF@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
TLS2_k127_3553125_3	365044.Pnap_3829	1.353e-46	168.0	COG0747@1|root,COG0747@2|Bacteria,1MWR7@1224|Proteobacteria,2VN67@28216|Betaproteobacteria,4AGQF@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
TLS2_k127_3561830_1	1458275.AZ34_15830	3.588e-145	464.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria,4ABPX@80864|Comamonadaceae	28216|Betaproteobacteria	G	TIGRFAM TRAP dicarboxylate transporter, DctP subunit	-	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
TLS2_k127_3561830_2	864051.BurJ1DRAFT_4866	7.376e-90	302.0	COG1192@1|root,COG1192@2|Bacteria,1N4FM@1224|Proteobacteria,2VNTX@28216|Betaproteobacteria,1KKSN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3561830_0	1380370.JIBA01000012_gene3757	4.014e-265	841.0	COG0366@1|root,COG0366@2|Bacteria,2GJUT@201174|Actinobacteria,4FEZA@85021|Intrasporangiaceae	201174|Actinobacteria	G	Alpha-amylase domain	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Alpha-amylase,Glyco_hydro_77
TLS2_k127_3564289_3	1121930.AQXG01000002_gene2343	9.514e-35	145.0	COG2382@1|root,COG2819@1|root,COG2382@2|Bacteria,COG2819@2|Bacteria,4NGJB@976|Bacteroidetes	976|Bacteroidetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
TLS2_k127_3564289_7	987059.RBXJA2T_09502	7.058e-05	50.0	2EPDE@1|root,33H00@2|Bacteria,1NIA5@1224|Proteobacteria,2VY7F@28216|Betaproteobacteria,1KMVS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3564289_2	395495.Lcho_2114	3.301e-75	259.0	COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,2VQ9D@28216|Betaproteobacteria,1KKPB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1415)	-	-	-	ko:K09941	-	-	-	-	ko00000	-	-	-	DUF1415
TLS2_k127_3564289_1	395495.Lcho_0153	4.687e-137	443.0	COG1893@1|root,COG1893@2|Bacteria,1MVZ1@1224|Proteobacteria,2VJFW@28216|Betaproteobacteria,1KK6F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	2-dehydropantoate 2-reductase	panE2	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
TLS2_k127_3564289_4	136993.KB900626_gene1918	5.411e-31	143.0	COG0664@1|root,COG0664@2|Bacteria,1Q93V@1224|Proteobacteria,2TTEY@28211|Alphaproteobacteria,3701B@31993|Methylocystaceae	28211|Alphaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
TLS2_k127_3564289_0	987059.RBXJA2T_14481	0.0	1234.0	COG0045@1|root,COG1042@1|root,COG1247@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,1KIV3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Succinyl-CoA ligase like flavodoxin domain	yfiQ	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
TLS2_k127_3564289_6	1045855.DSC_01370	7.93e-17	93.0	COG0457@1|root,COG0515@1|root,COG3063@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3063@2|Bacteria,1MVEU@1224|Proteobacteria,1S0IU@1236|Gammaproteobacteria,1X52Q@135614|Xanthomonadales	135614|Xanthomonadales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12,TPR_8
TLS2_k127_3570129_0	420662.Mpe_A0011	3.829e-317	975.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
TLS2_k127_3570129_1	420662.Mpe_A1531	1.085e-32	129.0	2EBAD@1|root,335AZ@2|Bacteria,1N6VF@1224|Proteobacteria,2VWWE@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3570129_2	391735.Veis_4015	2.584e-18	90.0	2EU10@1|root,33MI2@2|Bacteria,1NPW2@1224|Proteobacteria,2W6GT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3584094_4	1268622.AVS7_01320	3.744e-10	61.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,4AA1A@80864|Comamonadaceae	28216|Betaproteobacteria	L	Belongs to the DEAD box helicase family	rhlE2	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
TLS2_k127_3584094_0	987059.RBXJA2T_06460	6.423e-105	355.0	COG0313@1|root,COG0313@2|Bacteria,1RARW@1224|Proteobacteria,2VQ34@28216|Betaproteobacteria,1KJZF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase	rsmI_2	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
TLS2_k127_3584094_1	987059.RBXJA2T_06455	5.93e-92	305.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2VQUQ@28216|Betaproteobacteria,1KKN2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Maf-like protein	yceF	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
TLS2_k127_3584094_2	987059.RBXJA2T_06450	2.607e-44	169.0	COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,2VUIG@28216|Betaproteobacteria,1KM8F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
TLS2_k127_3584094_3	983917.RGE_41150	1.736e-31	124.0	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,2VVP5@28216|Betaproteobacteria,1KMN3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
TLS2_k127_3591126_0	987059.RBXJA2T_00085	1.272e-132	445.0	COG2199@1|root,COG3447@1|root,COG3614@1|root,COG5002@1|root,COG3447@2|Bacteria,COG3614@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1R7HC@1224|Proteobacteria,2WI6A@28216|Betaproteobacteria,1KJYG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,MASE1,Response_reg
TLS2_k127_3591126_1	395495.Lcho_0271	9.032e-65	222.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2VJ1W@28216|Betaproteobacteria,1KJJG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
TLS2_k127_3598119_0	395495.Lcho_2033	1.013e-183	584.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,1KJH8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
TLS2_k127_3598119_1	395495.Lcho_2032	2.885e-156	499.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2WEDQ@28216|Betaproteobacteria,1KJGJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
TLS2_k127_3600791_3	983917.RGE_27620	7.798e-94	321.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria,1KK1G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
TLS2_k127_3600791_1	987059.RBXJA2T_08048	4.022e-128	420.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2VIFF@28216|Betaproteobacteria,1KJ8M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS2_k127_3600791_2	987059.RBXJA2T_08043	2.296e-104	350.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,1KK72@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
TLS2_k127_3600791_0	987059.RBXJA2T_08038	6.032e-311	974.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria,1KJVW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KL	HELICc2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
TLS2_k127_3600791_5	1538295.JY96_00905	1.066e-22	100.0	COG5481@1|root,COG5481@2|Bacteria,1NAQ6@1224|Proteobacteria,2VW3I@28216|Betaproteobacteria,1KMK5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
TLS2_k127_3600791_4	420662.Mpe_A2007	1.661e-50	193.0	COG0631@1|root,COG0631@2|Bacteria,1N72S@1224|Proteobacteria,2VK9S@28216|Betaproteobacteria,1KJPH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Serine threonine protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
TLS2_k127_3609381_0	864051.BurJ1DRAFT_3305	1.294e-52	197.0	COG0607@1|root,COG0607@2|Bacteria,1N3RN@1224|Proteobacteria,2W30J@28216|Betaproteobacteria,1KNPI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS2_k127_3609381_3	395495.Lcho_3746	1.836e-34	134.0	COG1937@1|root,COG1937@2|Bacteria,1PUF5@1224|Proteobacteria,2VVJA@28216|Betaproteobacteria,1KMC3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
TLS2_k127_3609381_2	452637.Oter_1462	5.256e-42	168.0	COG0607@1|root,COG2391@1|root,COG0607@2|Bacteria,COG2391@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	2.8.1.1,2.8.1.2	ko:K00406,ko:K01011,ko:K07112	ko00190,ko00270,ko00920,ko01100,ko01120,ko02020,ko04122,map00190,map00270,map00920,map01100,map01120,map02020,map04122	M00156	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	PALP,Rhodanese,Sulf_transp
TLS2_k127_3609381_1	945713.IALB_1660	1.965e-42	161.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
TLS2_k127_3610158_1	522306.CAP2UW1_0277	1.494e-17	89.0	2CCB6@1|root,32YGR@2|Bacteria,1NC64@1224|Proteobacteria,2VWKT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
TLS2_k127_3610158_0	1100720.ALKN01000035_gene998	2.704e-248	773.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,2VK2V@28216|Betaproteobacteria,4ABET@80864|Comamonadaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
TLS2_k127_3612227_0	983917.RGE_03790	6.481e-186	607.0	COG5322@1|root,COG5322@2|Bacteria,1R60X@1224|Proteobacteria,2W0QF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3612227_1	983917.RGE_03800	3.934e-124	404.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VUHF@28216|Betaproteobacteria,1KPGU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
TLS2_k127_361564_4	983917.RGE_40920	7.279e-25	106.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,1KJ6P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
TLS2_k127_361564_0	365044.Pnap_0232	1.637e-222	714.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria	1224|Proteobacteria	G	'PFAM Alpha amylase, catalytic	-	GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006066,GO:0006073,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016757,GO:0019400,GO:0019751,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0051472,GO:0071704,GO:1901615	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
TLS2_k127_361564_1	29581.BW37_00067	4.148e-201	638.0	COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,2VNA1@28216|Betaproteobacteria,476QD@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
TLS2_k127_361564_3	1198452.Jab_2c33060	3.487e-54	207.0	COG0524@1|root,COG0524@2|Bacteria,1PQ76@1224|Proteobacteria,2VMDN@28216|Betaproteobacteria,478ND@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
TLS2_k127_361564_2	1198452.Jab_2c33080	1.358e-182	589.0	COG4772@1|root,COG4772@2|Bacteria,1QUXZ@1224|Proteobacteria	1224|Proteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
TLS2_k127_3617116_4	595537.Varpa_2131	9.499e-12	67.0	COG0671@1|root,COG0671@2|Bacteria,1RFUF@1224|Proteobacteria,2VRMF@28216|Betaproteobacteria,4AEIS@80864|Comamonadaceae	28216|Betaproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
TLS2_k127_3617116_2	543728.Vapar_1847	4.012e-26	109.0	COG0236@1|root,COG0236@2|Bacteria,1NGVI@1224|Proteobacteria,2VXRY@28216|Betaproteobacteria,4AIM8@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TLS2_k127_3617116_0	1157708.KB907456_gene2391	9.389e-176	562.0	COG0304@1|root,COG0304@2|Bacteria,1MV30@1224|Proteobacteria,2VI0P@28216|Betaproteobacteria,4ACTT@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS2_k127_3617116_1	864051.BurJ1DRAFT_3798	2.458e-117	387.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,2VHTU@28216|Betaproteobacteria,1KJK3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF808)	yedI	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
TLS2_k127_3617116_3	983917.RGE_38630	6.109e-21	94.0	2E7T6@1|root,3328B@2|Bacteria,1N8UT@1224|Proteobacteria,2VVWC@28216|Betaproteobacteria,1KMKS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_362859_1	983917.RGE_29020	2.743e-37	151.0	COG3318@1|root,COG3318@2|Bacteria,1R4KR@1224|Proteobacteria,2VSZR@28216|Betaproteobacteria,1KMFI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Uncharacterised protein family (UPF0149)	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	SEC-C,UPF0149
TLS2_k127_362859_3	420662.Mpe_A2197	1.425e-17	84.0	COG2501@1|root,COG2501@2|Bacteria,1N7NW@1224|Proteobacteria,2VVQY@28216|Betaproteobacteria,1KMP3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	S4 domain	ybcJ	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
TLS2_k127_362859_0	1216976.AX27061_4808	2.441e-60	219.0	COG2128@1|root,COG2128@2|Bacteria,1MVWP@1224|Proteobacteria,2VS89@28216|Betaproteobacteria,3T3PQ@506|Alcaligenaceae	28216|Betaproteobacteria	S	Alkylhydroperoxidase AhpD family core domain-containing protein 7	-	-	-	-	-	-	-	-	-	-	-	-	CMD
TLS2_k127_362859_2	864051.BurJ1DRAFT_4003	7.135e-18	93.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJA5@28216|Betaproteobacteria,1KIVU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406,ko:K05874	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,NIT
TLS2_k127_3643195_0	880073.Calab_3717	2.424e-100	344.0	COG1232@1|root,COG1232@2|Bacteria,2NQ1W@2323|unclassified Bacteria	2|Bacteria	H	Flavin containing amine oxidoreductase	hemG	-	1.14.19.9,1.3.3.15,1.3.3.4	ko:K00231,ko:K14266	ko00404,ko00860,ko01100,ko01110,ko01130,map00404,map00860,map01100,map01110,map01130	M00121,M00789,M00790	R03222,R04178,R09570	RC00885,RC00949	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09325	Amino_oxidase
TLS2_k127_3643195_1	666681.M301_1741	1.185e-39	160.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,2W303@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CHASE,EAL,GGDEF,MASE1,PAS,PAS_4,PAS_9,dCache_1
TLS2_k127_3648445_3	983917.RGE_12250	9.607e-103	338.0	COG2188@1|root,COG2188@2|Bacteria,1MUEB@1224|Proteobacteria,2VJ6N@28216|Betaproteobacteria,1KJ1W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	UTRA	frlR	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
TLS2_k127_3648445_5	864051.BurJ1DRAFT_2088	2.747e-58	206.0	COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,2VSEG@28216|Betaproteobacteria,1KM6B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Succinate dehydrogenase cytochrome b556 subunit	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
TLS2_k127_3648445_4	1157708.KB907452_gene3513	5.633e-60	210.0	COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,2VSJN@28216|Betaproteobacteria,4AEP5@80864|Comamonadaceae	28216|Betaproteobacteria	C	TIGRFAM Succinate dehydrogenase, hydrophobic membrane anchor	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
TLS2_k127_3648445_0	420662.Mpe_A2168	0.0	1074.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,1KJ0V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
TLS2_k127_3648445_2	420662.Mpe_A2167	1.136e-144	459.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VIKC@28216|Betaproteobacteria,1KJQS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
TLS2_k127_3648445_7	1286631.X805_25680	5.295e-33	130.0	COG2938@1|root,COG2938@2|Bacteria,1N2AS@1224|Proteobacteria,2VVYR@28216|Betaproteobacteria,1KMEM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
TLS2_k127_3648445_1	864051.BurJ1DRAFT_2093	5.776e-266	821.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VIJF@28216|Betaproteobacteria,1KJII@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
TLS2_k127_3648445_6	983917.RGE_34820	9.098e-37	141.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,1KJ9Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	NlpB/DapX lipoprotein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
TLS2_k127_3657639_1	365046.Rta_03080	1.872e-85	302.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2VK1C@28216|Betaproteobacteria,4ABW6@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS2_k127_3657639_0	983917.RGE_01190	1.073e-92	308.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2VIJH@28216|Betaproteobacteria,1KN5N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	NMT1-like family	nasF	-	-	ko:K02051,ko:K15576,ko:K22067	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko02000,ko02022	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17	-	-	NMT1_2
TLS2_k127_3669083_8	983917.RGE_03430	3.762e-46	169.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,2VSVX@28216|Betaproteobacteria,1KM1V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
TLS2_k127_3669083_4	983917.RGE_03440	2.109e-70	239.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2VRBD@28216|Betaproteobacteria,1KKUW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
TLS2_k127_3669083_2	987059.RBXJA2T_02195	2.491e-90	301.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2VQ4W@28216|Betaproteobacteria,1KJY4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
TLS2_k127_3669083_7	398578.Daci_1038	2.011e-48	176.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2VSH0@28216|Betaproteobacteria,4AE21@80864|Comamonadaceae	28216|Betaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
TLS2_k127_3669083_1	864051.BurJ1DRAFT_0385	2.024e-90	299.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2VQ80@28216|Betaproteobacteria,1KKM6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
TLS2_k127_3669083_10	987059.RBXJA2T_02210	2.164e-22	97.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,2VVPT@28216|Betaproteobacteria,1KMNP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
TLS2_k127_3669083_6	987059.RBXJA2T_02215	3.553e-65	226.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2VRAK@28216|Betaproteobacteria,1KKSV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
TLS2_k127_3669083_0	987059.RBXJA2T_02220	6.654e-254	792.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2VHQH@28216|Betaproteobacteria,1KJGH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
TLS2_k127_3669083_9	1158292.JPOE01000005_gene615	5.579e-40	149.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU9X@28216|Betaproteobacteria,1KM9P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
TLS2_k127_3669083_11	987059.RBXJA2T_02230	1.498e-14	77.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,2VXPQ@28216|Betaproteobacteria,1KMSK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
TLS2_k127_3669083_5	983917.RGE_03530	1.281e-66	228.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2VR2K@28216|Betaproteobacteria,1KKTC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
TLS2_k127_3669083_3	864051.BurJ1DRAFT_0393	1.346e-78	263.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2VR8I@28216|Betaproteobacteria,1KKRV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
TLS2_k127_3669083_12	596154.Alide2_4353	0.0001242	44.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2VGZH@28216|Betaproteobacteria,4AAGU@80864|Comamonadaceae	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
TLS2_k127_3672170_0	987059.RBXJA2T_09367	4.624e-174	551.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,1KJGR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
TLS2_k127_3672170_1	987059.RBXJA2T_09372	4.832e-62	230.0	COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2VSSQ@28216|Betaproteobacteria,1KM0H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
TLS2_k127_3672170_2	983917.RGE_33830	2.856e-09	58.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria,1KJF7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
TLS2_k127_3678475_2	987059.RBXJA2T_09302	3.873e-93	313.0	COG0793@1|root,COG0793@2|Bacteria,1MUA3@1224|Proteobacteria,2VKBJ@28216|Betaproteobacteria,1KN7U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	PDZ,PDZ_2,Peptidase_S41
TLS2_k127_3678475_1	983917.RGE_33930	1.24e-184	581.0	COG0516@1|root,COG0516@2|Bacteria,1MUJM@1224|Proteobacteria,2VJMM@28216|Betaproteobacteria,1KIUP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides	guaC	-	1.7.1.7	ko:K00364	ko00230,map00230	-	R01134	RC00457	ko00000,ko00001,ko01000	-	-	-	IMPDH
TLS2_k127_3678475_0	987059.RBXJA2T_09327	0.0	1253.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VH4I@28216|Betaproteobacteria,1KJ39@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
TLS2_k127_3697115_2	983917.RGE_02420	2.932e-39	148.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VH8F@28216|Betaproteobacteria,1KJ58@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
TLS2_k127_3697115_0	983917.RGE_02430	2.236e-58	213.0	29SCQ@1|root,30DHC@2|Bacteria,1RGDC@1224|Proteobacteria,2VSB9@28216|Betaproteobacteria,1KKY4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3697115_1	983917.RGE_02440	3.812e-49	179.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,1KJ0G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	ABC transporter	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
TLS2_k127_3755090_2	983917.RGE_27940	2.676e-109	360.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,1KKBJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
TLS2_k127_3755090_1	987059.RBXJA2T_19141	5.801e-215	675.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,1KJCI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
TLS2_k127_3755090_0	864051.BurJ1DRAFT_2993	0.0	1604.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHZQ@28216|Betaproteobacteria,1KIUR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS2_k127_3779308_2	395495.Lcho_2997	3.919e-181	571.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KJJD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	JKL	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	dbpA	GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0008026,GO:0008135,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042623,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065007,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	3.6.4.13	ko:K05591,ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
TLS2_k127_3779308_9	272560.BPSL2358	4.375e-67	238.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VQMN@28216|Betaproteobacteria,1K92F@119060|Burkholderiaceae	28216|Betaproteobacteria	O	4Fe-4S single cluster domain	nrdG	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
TLS2_k127_3779308_12	1437824.BN940_07921	1.162e-18	90.0	COG1328@1|root,COG1328@2|Bacteria,1N8MB@1224|Proteobacteria,2VW43@28216|Betaproteobacteria,3T4PM@506|Alcaligenaceae	28216|Betaproteobacteria	F	Anaerobic ribonucleoside-triphosphate reductase	-	-	-	-	-	-	-	-	-	-	-	-	NRDD
TLS2_k127_3779308_0	338969.Rfer_0368	0.0	1121.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,2VJYM@28216|Betaproteobacteria,4ABIQ@80864|Comamonadaceae	28216|Betaproteobacteria	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
TLS2_k127_3779308_8	257310.BB3252	3.774e-84	283.0	COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,2VQ1J@28216|Betaproteobacteria,3T4E1@506|Alcaligenaceae	28216|Betaproteobacteria	C	Nitroreductase family	rutE	-	-	ko:K09019	ko00240,ko01100,map00240,map01100	-	R09289	RC00087	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
TLS2_k127_3779308_1	983917.RGE_03970	1.049e-190	602.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2VI0M@28216|Betaproteobacteria,1KJEX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	epimerase dehydratase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
TLS2_k127_3779308_10	987059.RBXJA2T_07633	3.818e-52	194.0	2C3MR@1|root,32RCH@2|Bacteria,1QZ0P@1224|Proteobacteria,2WI68@28216|Betaproteobacteria,1KNWG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3779308_3	987059.RBXJA2T_10636	7.666e-139	455.0	COG0454@1|root,COG0456@2|Bacteria,1R8GF@1224|Proteobacteria,2VNUV@28216|Betaproteobacteria	28216|Betaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,PilZ
TLS2_k127_3779308_5	1123393.KB891316_gene1863	3.172e-92	313.0	COG5265@1|root,COG5265@2|Bacteria,1MWU5@1224|Proteobacteria,2VHDB@28216|Betaproteobacteria	28216|Betaproteobacteria	O	HPr kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3779308_7	522306.CAP2UW1_2882	4.987e-87	310.0	28JAH@1|root,2Z95A@2|Bacteria,1MXKT@1224|Proteobacteria,2VI69@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
TLS2_k127_3779308_6	983917.RGE_03980	5.54e-88	297.0	COG0265@1|root,COG0265@2|Bacteria,1R9ZV@1224|Proteobacteria,2VQ55@28216|Betaproteobacteria,1KNJQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
TLS2_k127_3779308_4	987059.RBXJA2T_10666	1.629e-124	411.0	COG0457@1|root,COG3118@1|root,COG5010@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,COG5010@2|Bacteria,1MXMD@1224|Proteobacteria,2VIMP@28216|Betaproteobacteria,1KNGG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
TLS2_k127_3780722_7	983917.RGE_15460	2.549e-51	193.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,2VSD5@28216|Betaproteobacteria,1KKTV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
TLS2_k127_3780722_5	1286631.X805_39120	2.211e-61	212.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,1KM71@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
TLS2_k127_3780722_4	1100721.ALKO01000015_gene1094	1.558e-71	243.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ2I@28216|Betaproteobacteria,4ADIW@80864|Comamonadaceae	28216|Betaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
TLS2_k127_3780722_1	983917.RGE_15420	6.887e-234	727.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,1KIUB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
TLS2_k127_3780722_3	864051.BurJ1DRAFT_3629	2.741e-93	308.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2VRGK@28216|Betaproteobacteria,1KK06@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulator	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
TLS2_k127_3780722_6	987059.RBXJA2T_12592	9.856e-61	215.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2VSKW@28216|Betaproteobacteria,1KM3K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	ptpA	GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
TLS2_k127_3780722_0	987059.RBXJA2T_12587	0.0	1153.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2VHFQ@28216|Betaproteobacteria,1KJZ2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
TLS2_k127_3780722_2	983917.RGE_15380	6.204e-202	635.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,2VHNH@28216|Betaproteobacteria,1KJC9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	PFAM Aminotransferase class I and II	tyrB	-	2.6.1.57	ko:K00832	ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	M00024,M00025,M00034,M00040	R00694,R00734,R01731,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS2_k127_3787342_1	296591.Bpro_0948	6.729e-72	244.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2VKTW@28216|Betaproteobacteria,4ABDV@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
TLS2_k127_3787342_0	1268622.AVS7_02616	1.346e-79	271.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2VQ2S@28216|Betaproteobacteria,4ADI1@80864|Comamonadaceae	28216|Betaproteobacteria	S	Smr protein MutS2	smrA	-	-	-	-	-	-	-	-	-	-	-	Smr
TLS2_k127_3787342_2	1100720.ALKN01000007_gene2968	7.654e-42	158.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,2VTH4@28216|Betaproteobacteria,4AF4K@80864|Comamonadaceae	28216|Betaproteobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	Asp_protease_2,gag-asp_proteas
TLS2_k127_3790393_2	983917.RGE_12510	1.484e-50	183.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,1KJ0A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	COG3170 Tfp pilus assembly protein FimV	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
TLS2_k127_3790393_1	983917.RGE_12500	3.004e-195	617.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2VH2N@28216|Betaproteobacteria,1KKF7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
TLS2_k127_3790393_0	864051.BurJ1DRAFT_3944	2.774e-198	625.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VH2M@28216|Betaproteobacteria,1KJSC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
TLS2_k127_3790393_3	983917.RGE_12480	6.028e-21	92.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,1KK7A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
TLS2_k127_3792354_1	983917.RGE_31900	1.372e-131	424.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,1KJR0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
TLS2_k127_3792354_5	983917.RGE_31910	1.448e-09	60.0	COG4736@1|root,COG4736@2|Bacteria,1PUF6@1224|Proteobacteria,2VXME@28216|Betaproteobacteria,1KMUA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Cbb3-type cytochrome oxidase	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
TLS2_k127_3792354_2	983917.RGE_31920	2.753e-111	367.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria,1KJRV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	cytochrome C oxidase	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
TLS2_k127_3792354_0	395495.Lcho_2779	2.738e-293	904.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,1KK0W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
TLS2_k127_3792354_4	983917.RGE_31940	2.027e-14	77.0	COG3197@1|root,COG3197@2|Bacteria,1PUR2@1224|Proteobacteria,2VXMN@28216|Betaproteobacteria,1KMS7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	cytochrome oxidase maturation protein	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
TLS2_k127_3792354_3	983917.RGE_31950	1.735e-20	91.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,1KJDU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
TLS2_k127_3829869_1	983917.RGE_09460	1.423e-130	422.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2VIYT@28216|Betaproteobacteria,1KJKM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
TLS2_k127_3829869_3	987059.RBXJA2T_14306	4.471e-23	105.0	COG3116@1|root,COG3116@2|Bacteria,1N95M@1224|Proteobacteria,2VVTP@28216|Betaproteobacteria,1KMIW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
TLS2_k127_3829869_0	987059.RBXJA2T_14301	9.759e-234	741.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2VIZM@28216|Betaproteobacteria,1KJCM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
TLS2_k127_3829869_2	395495.Lcho_0517	3.908e-26	110.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2WGFS@28216|Betaproteobacteria,1KJT6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS2_k127_3837721_3	1265502.KB905930_gene1563	5.149e-155	491.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria,4A9MU@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM aminotransferase, class I and II	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS2_k127_3837721_1	987059.RBXJA2T_19561	3.265e-232	739.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2VH9T@28216|Betaproteobacteria,1KJ3I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
TLS2_k127_3837721_0	983917.RGE_32580	1.454e-244	761.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2VHR6@28216|Betaproteobacteria,1KK4V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
TLS2_k127_3837721_2	987059.RBXJA2T_19571	1.839e-183	599.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VIFK@28216|Betaproteobacteria,1KJ3C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Molybdenum cofactor synthesis domain protein	moeA1	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
TLS2_k127_3837721_4	983917.RGE_32560	1.032e-24	105.0	COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,2VVSP@28216|Betaproteobacteria,1KMNH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
TLS2_k127_3855403_2	864051.BurJ1DRAFT_3930	1.911e-104	351.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2VH5S@28216|Betaproteobacteria,1KJPY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
TLS2_k127_3855403_1	987059.RBXJA2T_00929	2.032e-208	655.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2WGGJ@28216|Betaproteobacteria,1KJJ8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.48	ko:K01739,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
TLS2_k127_3855403_0	983917.RGE_12600	1.209e-277	858.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2VJM1@28216|Betaproteobacteria,1KK9C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
TLS2_k127_3864546_2	1504672.669783171	1.056e-72	264.0	COG3639@1|root,COG3639@2|Bacteria,1MW4F@1224|Proteobacteria,2VI8W@28216|Betaproteobacteria,4ABGX@80864|Comamonadaceae	28216|Betaproteobacteria	P	phosphonate ABC transporter, inner membrane subunit	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
TLS2_k127_3864546_1	522306.CAP2UW1_1696	9.17e-120	394.0	COG3221@1|root,COG3221@2|Bacteria,1PG76@1224|Proteobacteria,2VSRX@28216|Betaproteobacteria,1KR4X@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
TLS2_k127_3864546_0	864051.BurJ1DRAFT_3428	2.247e-175	553.0	COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,2VKSA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
TLS2_k127_3864546_3	1121035.AUCH01000017_gene2260	9.884e-57	204.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,2VRMP@28216|Betaproteobacteria,2KWGQ@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS2_k127_3864546_5	381666.H16_B2412	1.377e-08	61.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2WDYY@28216|Betaproteobacteria,1KBA2@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
TLS2_k127_3891105_6	983917.RGE_35130	1.425e-25	108.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2VI5H@28216|Betaproteobacteria,1KJF2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	yijE_1	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS2_k127_3891105_4	1265502.KB905954_gene417	1.19e-65	250.0	COG2863@1|root,COG2863@2|Bacteria,1MZU1@1224|Proteobacteria,2VU50@28216|Betaproteobacteria,4AAKY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome c class I	cytC2	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
TLS2_k127_3891105_1	987059.RBXJA2T_08068	8.874e-167	528.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2VH9H@28216|Betaproteobacteria,1KJPE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
TLS2_k127_3891105_3	987059.RBXJA2T_08073	3.341e-95	314.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2VKTD@28216|Betaproteobacteria,1KJ0Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS2_k127_3891105_0	987059.RBXJA2T_08078	0.0	1137.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2VN0X@28216|Betaproteobacteria,1KPBW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
TLS2_k127_3891105_7	1411123.JQNH01000001_gene1777	1.637e-13	75.0	COG4456@1|root,COG4456@2|Bacteria,1PF7P@1224|Proteobacteria,2UMGE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antidote-toxin recognition MazE, bacterial antitoxin	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
TLS2_k127_3891105_5	1449350.OCH239_09805	1.747e-28	119.0	COG1487@1|root,COG1487@2|Bacteria,1MZB6@1224|Proteobacteria,2U9C1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC_2	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
TLS2_k127_3891105_2	864051.BurJ1DRAFT_1406	9.585e-156	494.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,2VJ99@28216|Betaproteobacteria,1KJD4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
TLS2_k127_3896987_1	266117.Rxyl_2946	1.679e-114	403.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
TLS2_k127_3896987_3	1158292.JPOE01000002_gene1941	5.042e-21	94.0	2DNSI@1|root,32YXC@2|Bacteria,1N7K2@1224|Proteobacteria,2VVXF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3896987_0	983917.RGE_41760	2.541e-162	516.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2VI91@28216|Betaproteobacteria,1KJP4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	RNA polymerase sigma factor RpoH	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
TLS2_k127_3896987_2	983917.RGE_41770	3.16e-81	276.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,1KKS4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Electron transport protein SCO1 SenC	senC	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
TLS2_k127_3896987_4	1286631.X805_19190	6.282e-14	71.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2VHZU@28216|Betaproteobacteria,1KJ38@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
TLS2_k127_3904824_1	864051.BurJ1DRAFT_3335	8.938e-162	514.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,2VPBV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
TLS2_k127_3904824_0	864051.BurJ1DRAFT_3336	7.519e-256	795.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,2VPWJ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	sulfite reductase, dissimilatory-type alpha subunit	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
TLS2_k127_3904824_2	864051.BurJ1DRAFT_3337	5.035e-24	103.0	2EMP6@1|root,33FBM@2|Bacteria,1NGBE@1224|Proteobacteria,2VYCB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_3926854_1	365046.Rta_27700	6.217e-78	267.0	COG2863@1|root,COG2863@2|Bacteria,1RGTS@1224|Proteobacteria,2VQDM@28216|Betaproteobacteria,4ACPF@80864|Comamonadaceae	28216|Betaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TLS2_k127_3926854_0	983917.RGE_38590	7.15e-180	566.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria,1KJTH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
TLS2_k127_3936826_4	1265502.KB905935_gene3038	5.563e-33	131.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,4AAK8@80864|Comamonadaceae	28216|Betaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
TLS2_k127_3936826_3	983917.RGE_27300	1.414e-65	229.0	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,2VRZI@28216|Betaproteobacteria,1KKYP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the skp family	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS2_k127_3936826_0	983917.RGE_27310	0.0	1157.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,1KJ34@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
TLS2_k127_3936826_1	983917.RGE_27320	1.668e-189	604.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,1KJM6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
TLS2_k127_3936826_2	987059.RBXJA2T_18031	1.046e-180	575.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,1KJI9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
TLS2_k127_3936826_5	983917.RGE_27340	2.092e-26	109.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2VMM0@28216|Betaproteobacteria,1KJZN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
TLS2_k127_3951001_5	1268622.AVS7_01316	2.535e-09	59.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VKGA@28216|Betaproteobacteria,4ABF7@80864|Comamonadaceae	28216|Betaproteobacteria	V	PFAM ABC transporter related	nosF	-	-	ko:K01990,ko:K19340	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC_tran
TLS2_k127_3951001_0	1268622.AVS7_01317	9.284e-123	401.0	COG1277@1|root,COG1277@2|Bacteria,1MWUZ@1224|Proteobacteria,2VJDE@28216|Betaproteobacteria,4AAX0@80864|Comamonadaceae	28216|Betaproteobacteria	S	ABC-2 family transporter protein	nosY	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2
TLS2_k127_3951001_1	983917.RGE_19160	1.388e-57	214.0	COG4314@1|root,COG4314@2|Bacteria,1RCDR@1224|Proteobacteria,2VIGY@28216|Betaproteobacteria,1KNTU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NosL	nosL	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
TLS2_k127_3951001_3	596154.Alide2_1364	2.61e-50	197.0	COG4314@1|root,COG4314@2|Bacteria,1N43A@1224|Proteobacteria,2VQI4@28216|Betaproteobacteria,4ADMG@80864|Comamonadaceae	28216|Betaproteobacteria	C	NosL	-	-	-	-	-	-	-	-	-	-	-	-	NosL
TLS2_k127_3951001_4	266264.Rmet_4918	6.257e-49	178.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VSPR@28216|Betaproteobacteria,1KA8G@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	nosC	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
TLS2_k127_3951001_2	267608.RSp1366	2.661e-54	199.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria,1K2GI@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	nosX	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
TLS2_k127_3981484_2	864051.BurJ1DRAFT_1523	4.841e-09	61.0	COG2972@1|root,COG2972@2|Bacteria,1R5R0@1224|Proteobacteria,2VM7Q@28216|Betaproteobacteria,1KN1G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
TLS2_k127_3981484_0	338969.Rfer_3458	1.953e-131	428.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,2VHF0@28216|Betaproteobacteria,4AAN1@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
TLS2_k127_3981484_1	1458427.BAWN01000035_gene1977	3.413e-38	148.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2VRGK@28216|Betaproteobacteria,4AAJV@80864|Comamonadaceae	28216|Betaproteobacteria	K	transcriptional regulator, Rrf2 family	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
TLS2_k127_3986211_0	395495.Lcho_1647	4.222e-201	634.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,1KJ5J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	1.8.1.4,2.3.1.12	ko:K00382,ko:K00627	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R02569,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS2_k127_3986211_1	864051.BurJ1DRAFT_2231	7.411e-77	265.0	COG5405@1|root,COG5405@2|Bacteria,1RAFD@1224|Proteobacteria,2VMEF@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM 20S proteasome, A and B subunits	-	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
TLS2_k127_4004805_0	1385517.N800_07415	4.894e-173	552.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1X57I@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_48,DUF3372
TLS2_k127_4004805_1	395495.Lcho_1558	5.782e-148	474.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2VHIK@28216|Betaproteobacteria,1KIZ4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
TLS2_k127_4010174_3	713587.THITH_11725	6.629e-121	399.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,1RQJI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Translation elongation factor	selB	GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
TLS2_k127_4010174_5	365046.Rta_30520	2.569e-10	73.0	2ENGM@1|root,33G44@2|Bacteria,1NIB7@1224|Proteobacteria,2VYFS@28216|Betaproteobacteria,4AG1A@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4010174_0	420662.Mpe_A1170	0.0	1738.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2VJG2@28216|Betaproteobacteria,1KK82@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhA	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
TLS2_k127_4010174_2	395495.Lcho_3727	1.215e-132	424.0	COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,2VJXP@28216|Betaproteobacteria,1KKF1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	fdhB	-	-	ko:K00124,ko:K07307	ko00630,ko00680,ko00920,ko01100,ko01120,ko01200,map00630,map00680,map00920,map01100,map01120,map01200	-	R00519,R09501	RC02555,RC02796	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11,Fer4_7
TLS2_k127_4010174_6	1276756.AUEX01000001_gene1061	1.472e-08	59.0	2EIHA@1|root,33C8N@2|Bacteria,1NG9G@1224|Proteobacteria,2VXQQ@28216|Betaproteobacteria,4AFRS@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4010174_1	1265502.KB905961_gene335	1.536e-148	480.0	COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,2VKTA@28216|Betaproteobacteria,4AB36@80864|Comamonadaceae	28216|Betaproteobacteria	C	TIGRFAM Formate dehydrogenase, gamma subunit	fdhC	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
TLS2_k127_4010174_4	395495.Lcho_3724	2.532e-23	107.0	2CKKR@1|root,332MC@2|Bacteria,1NCAT@1224|Proteobacteria,2VW6M@28216|Betaproteobacteria,1KMMV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_40468_5	987059.RBXJA2T_17372	2.462e-72	250.0	COG5490@1|root,COG5490@2|Bacteria,1R4SV@1224|Proteobacteria,2VQP2@28216|Betaproteobacteria,1KKR1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	TIGRFAM phasin family protein	phaP	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
TLS2_k127_40468_7	987059.RBXJA2T_17382	3.398e-60	216.0	COG0824@1|root,COG0824@2|Bacteria,1RGZN@1224|Proteobacteria,2VREZ@28216|Betaproteobacteria,1KKT4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
TLS2_k127_40468_4	864051.BurJ1DRAFT_2217	4.418e-111	374.0	COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,2VKIZ@28216|Betaproteobacteria,1KK4H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
TLS2_k127_40468_3	983917.RGE_23550	8.765e-149	481.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2VMN7@28216|Betaproteobacteria,1KKDP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.215,1.1.1.79,1.1.1.81	ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R01739	RC00031,RC00042,RC00084	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TLS2_k127_40468_0	420662.Mpe_A1514	2.015e-193	620.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2VJVZ@28216|Betaproteobacteria,1KK8Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
TLS2_k127_40468_1	983917.RGE_23590	2.15e-163	524.0	COG0477@1|root,COG2814@2|Bacteria,1R3WC@1224|Proteobacteria,2VKT9@28216|Betaproteobacteria,1KKFE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS2_k127_40468_6	983917.RGE_23600	3.843e-67	234.0	COG0695@1|root,COG0695@2|Bacteria,1N7X3@1224|Proteobacteria,2VVPB@28216|Betaproteobacteria,1KMDR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Glutaredoxin
TLS2_k127_40468_2	864051.BurJ1DRAFT_2226	6.022e-149	478.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2VI8C@28216|Betaproteobacteria,1KJNR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
TLS2_k127_4067843_3	864051.BurJ1DRAFT_3123	5.726e-109	359.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KJN7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
TLS2_k127_4067843_5	338969.Rfer_2238	1.341e-29	122.0	COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria,4AFKF@80864|Comamonadaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
TLS2_k127_4067843_6	1458275.AZ34_05120	9.718e-19	91.0	COG5393@1|root,COG5393@2|Bacteria,1NDFU@1224|Proteobacteria,2VX3I@28216|Betaproteobacteria,4AFUV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
TLS2_k127_4067843_0	864051.BurJ1DRAFT_3121	0.0	1019.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHES@28216|Betaproteobacteria,1KIX7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
TLS2_k127_4067843_1	1504672.669786746	2.782e-147	478.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2VJ1C@28216|Betaproteobacteria,4A9W7@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS2_k127_4067843_2	864051.BurJ1DRAFT_2442	1.153e-128	414.0	COG2197@1|root,COG2197@2|Bacteria,1Q7GF@1224|Proteobacteria,2VN5C@28216|Betaproteobacteria,1KKI8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS2_k127_4069072_0	864051.BurJ1DRAFT_1480	1.94e-206	644.0	COG0502@1|root,COG0502@2|Bacteria,1QWVD@1224|Proteobacteria,2WH18@28216|Betaproteobacteria,1KMSG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS2_k127_4069072_1	864051.BurJ1DRAFT_1479	9.405e-170	541.0	COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,2WHFN@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
TLS2_k127_4069072_2	864051.BurJ1DRAFT_1478	5.893e-73	256.0	2E0WZ@1|root,30TPT@2|Bacteria,1NP5P@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4097279_4	864051.BurJ1DRAFT_1066	5.663e-38	144.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2VR5R@28216|Betaproteobacteria,1KKPA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
TLS2_k127_4097279_0	983917.RGE_07580	3.45e-83	276.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2VQ07@28216|Betaproteobacteria,1KKPH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
TLS2_k127_4097279_3	420662.Mpe_A3158	9.897e-48	181.0	COG0454@1|root,COG0456@2|Bacteria,1QUZC@1224|Proteobacteria,2WGMV@28216|Betaproteobacteria,1KPD9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_3
TLS2_k127_4097279_2	864051.BurJ1DRAFT_1063	6.096e-57	211.0	2C9ES@1|root,32HUV@2|Bacteria,1RKUI@1224|Proteobacteria,2VSTQ@28216|Betaproteobacteria,1KM4N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2726)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2726
TLS2_k127_4097279_1	983917.RGE_07550	3.3e-64	225.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,1KK3E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
TLS2_k127_4098944_0	983917.RGE_09290	1.864e-301	939.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,1KKBE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	ABC transporter	atm1	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS2_k127_4098944_1	983917.RGE_09280	1.496e-37	162.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2VR9M@28216|Betaproteobacteria,1KKXD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
TLS2_k127_4102029_3	1123257.AUFV01000004_gene788	7.2e-42	171.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1X4U6@135614|Xanthomonadales	135614|Xanthomonadales	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N,ECH_1
TLS2_k127_4102029_0	1223521.BBJX01000004_gene2325	1.813e-188	601.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VHMS@28216|Betaproteobacteria,4ABPG@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
TLS2_k127_4102029_2	983917.RGE_32840	3.01e-53	192.0	COG0789@1|root,COG0789@2|Bacteria,1RH05@1224|Proteobacteria,2VTF0@28216|Betaproteobacteria,1KPBE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
TLS2_k127_4102029_1	983917.RGE_32870	8.413e-171	542.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VIYY@28216|Betaproteobacteria,1KNCK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Carboxyl transferase domain	-	-	6.4.1.5	ko:K13778	ko00281,map00281	-	R03494	RC00367,RC00942	ko00000,ko00001,ko01000	-	-	-	Carboxyl_trans
TLS2_k127_4102808_0	987059.RBXJA2T_18874	3.019e-233	725.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria,1KIWT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
TLS2_k127_4102808_6	595537.Varpa_2111	3.018e-51	186.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2VSE7@28216|Betaproteobacteria,4AEIH@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM Class I peptide chain release factor	yaeJ	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
TLS2_k127_4102808_3	1286631.X805_08820	6.382e-180	576.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria,1KJUS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
TLS2_k127_4102808_1	864051.BurJ1DRAFT_0232	1.496e-204	647.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2VIC5@28216|Betaproteobacteria,1KJ7R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EGP	Major Facilitator	lplT	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS2_k127_4102808_4	987059.RBXJA2T_18894	1.037e-114	389.0	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,2VQEZ@28216|Betaproteobacteria,1KK13@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS2_k127_4102808_7	987059.RBXJA2T_18899	3.494e-38	156.0	COG0745@1|root,COG0745@2|Bacteria,1N2T7@1224|Proteobacteria,2VUH7@28216|Betaproteobacteria,1KM9U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS2_k127_4102808_5	983917.RGE_01730	6.691e-76	257.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,2VR4K@28216|Betaproteobacteria,1KKJB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
TLS2_k127_4102808_2	983917.RGE_01740	7.904e-189	596.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,2VHNH@28216|Betaproteobacteria,1KK6G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Aminotransferase class I and II	tyrB	-	2.6.1.57	ko:K00832	ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	M00024,M00025,M00034,M00040	R00694,R00734,R01731,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS2_k127_4119611_1	1198452.Jab_2c09490	2.022e-164	529.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,2VKQ7@28216|Betaproteobacteria	28216|Betaproteobacteria	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
TLS2_k127_4119611_3	1123073.KB899241_gene2313	3.926e-62	223.0	COG0665@1|root,COG0665@2|Bacteria,1RH7N@1224|Proteobacteria,1S9ZE@1236|Gammaproteobacteria,1X834@135614|Xanthomonadales	135614|Xanthomonadales	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4119611_4	742823.HMPREF9465_00019	7.684e-05	52.0	2BV41@1|root,32QH4@2|Bacteria,1PK8C@1224|Proteobacteria,2W8I0@28216|Betaproteobacteria,4PR8S@995019|Sutterellaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4119611_0	338969.Rfer_1114	8.17e-216	696.0	COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,2VSIK@28216|Betaproteobacteria,4AHWT@80864|Comamonadaceae	28216|Betaproteobacteria	E	Tryptophan halogenase	-	-	1.14.19.9	ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
TLS2_k127_4119611_2	1500894.JQNN01000001_gene2755	3.088e-86	301.0	COG1629@1|root,COG1629@2|Bacteria,1MWTT@1224|Proteobacteria	1224|Proteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
TLS2_k127_4135022_2	1538295.JY96_03270	2.441e-27	117.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,1KKK3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
TLS2_k127_4135022_1	983917.RGE_26910	1.533e-93	312.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,2VMD6@28216|Betaproteobacteria,1KJBS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60,4.6.1.12	ko:K00991,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
TLS2_k127_4135022_0	987059.RBXJA2T_03364	7.801e-307	949.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,1KJDJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
TLS2_k127_4135618_2	983917.RGE_12620	2.979e-138	444.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2VH5S@28216|Betaproteobacteria,1KJPY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
TLS2_k127_4135618_0	631362.Thi970DRAFT_02692	1.099e-207	654.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,1WW2W@135613|Chromatiales	135613|Chromatiales	P	PFAM sodium hydrogen exchanger	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
TLS2_k127_4135618_3	243233.MCA0850	4.107e-102	344.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1XFW1@135618|Methylococcales	135618|Methylococcales	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
TLS2_k127_4135618_1	983917.RGE_36880	7.125e-160	523.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,2VHR0@28216|Betaproteobacteria,1KK31@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
TLS2_k127_4135618_4	864051.BurJ1DRAFT_4877	8.57e-72	245.0	2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,2VSTN@28216|Betaproteobacteria,1KKXU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
TLS2_k127_414533_5	983917.RGE_17340	2.486e-38	156.0	COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,2VH35@28216|Betaproteobacteria,1KK43@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MNOU	TIGRFAM flagellar rod assembly protein muramidase FlgJ	flgJ	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Rod-binding
TLS2_k127_414533_1	987059.RBXJA2T_04568	1.95e-153	493.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2VJAZ@28216|Betaproteobacteria,1KIXV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
TLS2_k127_414533_4	420662.Mpe_A3067	3.733e-73	260.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,2VRIC@28216|Betaproteobacteria,1KJYH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
TLS2_k127_414533_2	987059.RBXJA2T_04578	2.574e-120	392.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,2VH7A@28216|Betaproteobacteria,1KJ3E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	flagellar basal-body rod protein	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
TLS2_k127_414533_3	983917.RGE_17240	1.754e-104	344.0	COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,2VISC@28216|Betaproteobacteria,1KIXM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar basal-body rod protein FlgF	flgF	-	-	ko:K02391	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
TLS2_k127_414533_0	420662.Mpe_A3070	5.876e-179	569.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,2VIV1@28216|Betaproteobacteria,1KKBK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar hook protein FlgE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
TLS2_k127_415485_1	522306.CAP2UW1_0334	4.459e-16	80.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act,PATR
TLS2_k127_415485_4	522306.CAP2UW1_0335	2e-09	63.0	294AC@1|root,2ZRQJ@2|Bacteria,1PA56@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_415485_2	1454004.AW11_03877	4.909e-14	79.0	29799@1|root,2ZUGZ@2|Bacteria,1P46Y@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_415485_0	1286631.X805_25960	5.509e-145	481.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,1KJZW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	chemotaxis sensory transducer	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3
TLS2_k127_415485_3	1538295.JY96_08600	4.048e-12	69.0	COG0745@1|root,COG0745@2|Bacteria,1QWG0@1224|Proteobacteria,2WGYI@28216|Betaproteobacteria,1KPDN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KT	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Response_reg
TLS2_k127_4164501_4	983917.RGE_06830	1.649e-43	163.0	COG1518@1|root,COG1518@2|Bacteria,1MUXH@1224|Proteobacteria,2VMT9@28216|Betaproteobacteria	28216|Betaproteobacteria	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
TLS2_k127_4164501_6	272134.KB731324_gene4900	2.722e-14	80.0	COG2405@1|root,COG2405@2|Bacteria,1G6NZ@1117|Cyanobacteria,1HBGG@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF3368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
TLS2_k127_4164501_7	1123401.JHYQ01000001_gene1849	2.616e-08	59.0	COG2886@1|root,COG2886@2|Bacteria,1N9SY@1224|Proteobacteria,1SRR2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
TLS2_k127_4164501_3	1000565.METUNv1_02570	6.704e-76	268.0	2DMV2@1|root,32TV5@2|Bacteria,1RCB3@1224|Proteobacteria,2VTY3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CRISPR_assoc	casE	-	-	ko:K19126	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_assoc
TLS2_k127_4164501_2	1454004.AW11_00889	8.079e-86	289.0	2DBE4@1|root,2Z8QG@2|Bacteria,1RAK5@1224|Proteobacteria,2VTQH@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CRISPR-associated protein (Cas_Cas5)	casD	-	-	ko:K19125	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
TLS2_k127_4164501_1	1454004.AW11_00888	4.746e-154	494.0	COG1857@1|root,COG1857@2|Bacteria,1MVNH@1224|Proteobacteria,2VP5P@28216|Betaproteobacteria	28216|Betaproteobacteria	L	CT1975-like protein	casC	-	-	ko:K19124	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CT1975
TLS2_k127_4164501_5	1000565.METUNv1_02573	1.341e-41	166.0	2EMUR@1|root,33FH1@2|Bacteria,1NGE1@1224|Proteobacteria,2VY86@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CRISPR-associated protein Cse2 (CRISPR_cse2)	-	-	-	ko:K19046	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse2
TLS2_k127_4164501_0	1000565.METUNv1_02574	1.63e-195	622.0	arCOG04928@1|root,2Z880@2|Bacteria,1NBNZ@1224|Proteobacteria,2VNGI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CRISPR-associated protein Cse1 (CRISPR_cse1)	-	-	-	ko:K19123	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse1
TLS2_k127_4167125_2	987059.RBXJA2T_12112	2.969e-69	242.0	COG0835@1|root,COG0835@2|Bacteria,1N07Q@1224|Proteobacteria,2VU6N@28216|Betaproteobacteria,1KM5C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NT	CheW-like domain	pilI	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
TLS2_k127_4167125_4	864051.BurJ1DRAFT_4238	2.455e-66	227.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,2VSSD@28216|Betaproteobacteria,1KKZF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KT	PFAM response regulator receiver	pilH	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
TLS2_k127_4167125_3	987059.RBXJA2T_12122	2.775e-67	231.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,2VR2Q@28216|Betaproteobacteria,1KKU5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	cheY-homologous receiver domain	pilG	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
TLS2_k127_4167125_5	864051.BurJ1DRAFT_4240	4.72e-33	127.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,2VVP4@28216|Betaproteobacteria,1KMIY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	rubredoxin	rubA	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
TLS2_k127_4167125_0	983917.RGE_42130	4.629e-164	522.0	COG0351@1|root,COG0351@2|Bacteria,1QUEP@1224|Proteobacteria,2WEGK@28216|Betaproteobacteria,1KKCE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
TLS2_k127_4167125_1	864051.BurJ1DRAFT_4242	2.774e-99	329.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria,1KJX3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS2_k127_4168457_3	987059.RBXJA2T_04748	1.845e-107	351.0	COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2VIJ5@28216|Betaproteobacteria,1KJKI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Glutathione S-transferase	yibF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
TLS2_k127_4168457_0	983917.RGE_45440	2.312e-227	711.0	COG0402@1|root,COG0402@2|Bacteria,1MX34@1224|Proteobacteria,2VMF2@28216|Betaproteobacteria,1KJH4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Amidohydrolase family	codA	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
TLS2_k127_4168457_6	983917.RGE_45080	9.688e-58	204.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2VU5H@28216|Betaproteobacteria,1KM2I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	sigma 54 modulation protein ribosomal protein S30EA	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
TLS2_k127_4168457_4	983917.RGE_45090	8.571e-86	287.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2VRDH@28216|Betaproteobacteria,1KKME@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	IIA-like nitrogen-regulatory protein PtsN	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
TLS2_k127_4168457_1	987059.RBXJA2T_02807	1.53e-182	575.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2VJCH@28216|Betaproteobacteria,1KJRW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
TLS2_k127_4168457_5	983917.RGE_45110	4.804e-72	246.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2VR52@28216|Betaproteobacteria,1KKW6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
TLS2_k127_4168457_7	420662.Mpe_A0222	9.174e-51	186.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,2VRC6@28216|Betaproteobacteria,1KM0E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
TLS2_k127_4168457_2	983917.RGE_45130	3.584e-113	376.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2VJC3@28216|Betaproteobacteria,1KJ45@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
TLS2_k127_417159_3	983917.RGE_40770	9.834e-16	86.0	2ERQY@1|root,33JA6@2|Bacteria,1QUWX@1224|Proteobacteria,2WGWJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_417159_0	864051.BurJ1DRAFT_3669	1.14e-179	567.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VKSV@28216|Betaproteobacteria,1KN7P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
TLS2_k127_417159_2	864051.BurJ1DRAFT_3668	2.818e-61	218.0	2BKYI@1|root,32FF5@2|Bacteria,1MY1A@1224|Proteobacteria,2VRUQ@28216|Betaproteobacteria,1KNWV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
TLS2_k127_417159_1	864051.BurJ1DRAFT_3667	7.141e-89	295.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,1KNDZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
TLS2_k127_4180651_5	935557.ATYB01000014_gene2914	7.051e-10	59.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,4B96F@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Dehydrogenase	MA20_25935	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
TLS2_k127_4180651_1	983917.RGE_00750	1.129e-64	229.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,2VQIS@28216|Betaproteobacteria,1KKUY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
TLS2_k127_4180651_2	983917.RGE_00740	1.108e-52	191.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria,1KIYP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
TLS2_k127_4180651_3	987059.RBXJA2T_05093	9.636e-46	169.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2VU20@28216|Betaproteobacteria,1KMAT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
TLS2_k127_4180651_0	983917.RGE_00720	2.458e-117	387.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2VHI1@28216|Betaproteobacteria,1KJQ6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
TLS2_k127_4180651_4	1095769.CAHF01000022_gene133	4.262e-29	125.0	COG0071@1|root,COG0071@2|Bacteria,1N1RF@1224|Proteobacteria,2VT18@28216|Betaproteobacteria,474TC@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
TLS2_k127_4183853_0	987059.RBXJA2T_07513	1.524e-260	814.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,1KK1B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
TLS2_k127_4183853_1	983917.RGE_47040	2.466e-35	137.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,1KMJE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
TLS2_k127_4183853_2	983917.RGE_47050	5.768e-35	143.0	COG0594@1|root,COG0594@2|Bacteria,1RI80@1224|Proteobacteria,2VSD0@28216|Betaproteobacteria,1KMIX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	-	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
TLS2_k127_4183853_3	1123504.JQKD01000006_gene1598	2.917e-18	86.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2VXTS@28216|Betaproteobacteria,4AFCB@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
TLS2_k127_420533_2	1265502.KB905935_gene3124	4.26e-97	334.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,4AA6R@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Squalene phytoene synthase	hpnD	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
TLS2_k127_420533_1	987059.RBXJA2T_19156	3.077e-108	358.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,1KITY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Squalene/phytoene synthase	hpnC	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
TLS2_k127_420533_0	983917.RGE_27970	1.631e-120	398.0	COG0845@1|root,COG0845@2|Bacteria,1NJDF@1224|Proteobacteria,2VIS6@28216|Betaproteobacteria,1KK79@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS2_k127_420533_3	1286631.X805_03890	3.209e-42	156.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHZQ@28216|Betaproteobacteria,1KIUR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS2_k127_4222302_7	987059.RBXJA2T_02936	4.404e-17	83.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria,1KJ0S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
TLS2_k127_4222302_3	983917.RGE_43690	6.624e-134	435.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria,1KK97@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Transporter associated domain	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
TLS2_k127_4222302_2	864051.BurJ1DRAFT_0500	4.334e-187	590.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2VIHH@28216|Betaproteobacteria,1KK5M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Cobalamin synthesis protein	yjiA_1	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
TLS2_k127_4222302_5	987059.RBXJA2T_02921	3.247e-83	287.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2VQR5@28216|Betaproteobacteria,1KKPJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
TLS2_k127_4222302_0	983917.RGE_43720	4.954e-240	755.0	COG3170@1|root,COG3170@2|Bacteria,1QXJ7@1224|Proteobacteria,2WH5D@28216|Betaproteobacteria,1KKAA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
TLS2_k127_4222302_4	983917.RGE_43730	3.234e-95	316.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2VIFV@28216|Betaproteobacteria,1KJHV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
TLS2_k127_4222302_1	983917.RGE_43740	3.605e-215	677.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2VHG3@28216|Betaproteobacteria,1KK09@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
TLS2_k127_4222302_6	62928.azo0116	5.261e-45	165.0	COG0775@1|root,COG0775@2|Bacteria,1MUMQ@1224|Proteobacteria,2VKRE@28216|Betaproteobacteria,2KXRE@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	AMNp_N,PNP_UDP_1
TLS2_k127_4238828_2	742159.HMPREF0004_4296	5.846e-45	165.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,2VU7V@28216|Betaproteobacteria,3T83D@506|Alcaligenaceae	28216|Betaproteobacteria	J	Translation initiation factor	yciH	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
TLS2_k127_4238828_3	266265.Bxe_B1480	3.374e-41	168.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2VJEC@28216|Betaproteobacteria,1K69E@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
TLS2_k127_4238828_1	375286.mma_0084	1.43e-138	451.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,2VHCH@28216|Betaproteobacteria,472GC@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
TLS2_k127_4238828_0	1502852.FG94_02183	6.408e-151	492.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria	1224|Proteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
TLS2_k127_4238828_4	1123367.C666_00885	7.314e-30	129.0	COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,2VRRG@28216|Betaproteobacteria,2KVVA@206389|Rhodocyclales	206389|Rhodocyclales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
TLS2_k127_4251190_1	397945.Aave_1164	1.565e-67	232.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,4A9QQ@80864|Comamonadaceae	28216|Betaproteobacteria	E	TIGRFAM acetylornithine and succinylornithine	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS2_k127_4251190_0	1123504.JQKD01000014_gene861	1.572e-169	537.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,4AB2W@80864|Comamonadaceae	28216|Betaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
TLS2_k127_4251190_2	76114.ebA5097	3.246e-57	205.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,2KUUD@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
TLS2_k127_4254965_0	1328313.DS2_15714	1.304e-171	569.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RQHM@1236|Gammaproteobacteria,467Q9@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Alpha amylase, catalytic domain	malZ	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004558,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009311,GO:0009313,GO:0009987,GO:0015926,GO:0016052,GO:0016787,GO:0016798,GO:0030978,GO:0030980,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0051691,GO:0051692,GO:0071704,GO:0090599,GO:1901575	3.2.1.135,3.2.1.20	ko:K01187,ko:K21575	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH13,GH31	iECH74115_1262.ECH74115_0480,iEcSMS35_1347.EcSMS35_0434,iSFV_1184.SFV_0368,iYL1228.KPN_00344	Alpha-amylase,Alpha-amylase_N,Malt_amylase_C
TLS2_k127_4254965_1	987059.RBXJA2T_07348	2.151e-153	489.0	COG3833@1|root,COG3833@2|Bacteria,1QA3Z@1224|Proteobacteria,2VN8B@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	malG	-	-	ko:K10110	ko02010,map02010	M00194	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.22	-	-	BPD_transp_1
TLS2_k127_428055_0	338969.Rfer_1882	1.569e-79	284.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,4AGEM@80864|Comamonadaceae	28216|Betaproteobacteria	M	OmpA-like transmembrane domain	rmpM	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,SmpA_OmlA
TLS2_k127_428055_1	1123255.JHYS01000012_gene1365	4.594e-58	210.0	COG3134@1|root,COG3134@2|Bacteria,1MY27@1224|Proteobacteria,2VMUB@28216|Betaproteobacteria,4AD9C@80864|Comamonadaceae	28216|Betaproteobacteria	S	Beta/Gamma crystallin	-	-	-	-	-	-	-	-	-	-	-	-	Crystall,Rick_17kDa_Anti
TLS2_k127_4286263_0	1042209.HK44_005120	0.0	1731.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1YT9R@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K18138,ko:K18303	ko01501,ko01503,map01501,map01503	M00642,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.17	-	-	ACR_tran
TLS2_k127_4286263_1	1042209.HK44_005125	2.318e-149	486.0	COG0845@1|root,COG0845@2|Bacteria,1PH7U@1224|Proteobacteria,1RUWB@1236|Gammaproteobacteria,1YSFK@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
TLS2_k127_4286263_2	1151127.KB906326_gene761	5.685e-111	363.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN5K@1236|Gammaproteobacteria,1YSYV@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS2_k127_4292864_0	420662.Mpe_A3446	0.0	1121.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria,1KJ5X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
TLS2_k127_4292864_1	983917.RGE_03270	2.007e-252	782.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2VH5D@28216|Betaproteobacteria,1KJXX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
TLS2_k127_4292864_7	983917.RGE_03280	1.671e-56	198.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,2VSDQ@28216|Betaproteobacteria,1KKS8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
TLS2_k127_4292864_4	983917.RGE_03290	2.567e-125	405.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,2VJ3V@28216|Betaproteobacteria,1KJF4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
TLS2_k127_4292864_5	983917.RGE_03300	1.004e-114	379.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,2VHS6@28216|Betaproteobacteria,1KJ71@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
TLS2_k127_4292864_10	983917.RGE_03310	1.033e-47	178.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,2VU1C@28216|Betaproteobacteria,1KM7R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
TLS2_k127_4292864_2	987059.RBXJA2T_02130	2.946e-173	544.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2VHSD@28216|Betaproteobacteria,1KJ2C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
TLS2_k127_4292864_9	983917.RGE_03330	2.401e-50	179.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,2VSGE@28216|Betaproteobacteria,1KM4Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
TLS2_k127_4292864_8	1538295.JY96_12730	1.692e-54	192.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,2VSE6@28216|Betaproteobacteria,1KM24@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
TLS2_k127_4292864_3	983917.RGE_03350	5.439e-146	466.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2VHQN@28216|Betaproteobacteria,1KIUV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
TLS2_k127_4292864_6	983917.RGE_03360	8.032e-79	264.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2VQ0A@28216|Betaproteobacteria,1KKJY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
TLS2_k127_4292864_12	987059.RBXJA2T_02155	6.319e-23	106.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2VVNT@28216|Betaproteobacteria,1KMIA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
TLS2_k127_4292864_11	987059.RBXJA2T_02160	3.491e-34	135.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2VU2G@28216|Betaproteobacteria,1KMEY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
TLS2_k127_4298832_1	420662.Mpe_A3348	3.527e-225	714.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria,1KJYM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Putative nucleotidyltransferase substrate binding domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
TLS2_k127_4298832_6	420662.Mpe_A0549	1.43e-25	110.0	2ETEI@1|root,33KYE@2|Bacteria,1NJKD@1224|Proteobacteria,2W43N@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4298832_0	983917.RGE_36710	0.0	1192.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,1KJH1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
TLS2_k127_4298832_2	420662.Mpe_A1163	1.175e-187	592.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,1KK2J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
TLS2_k127_4298832_5	748247.AZKH_3032	1.921e-51	198.0	COG2206@1|root,COG2206@2|Bacteria,1MWDU@1224|Proteobacteria,2VIAF@28216|Betaproteobacteria,2KZ48@206389|Rhodocyclales	206389|Rhodocyclales	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
TLS2_k127_4298832_4	1265502.KB905972_gene1347	8.29e-101	332.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,2VI7T@28216|Betaproteobacteria,4A9TG@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
TLS2_k127_4298832_3	75379.Tint_2351	8.475e-102	340.0	COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,2VJ01@28216|Betaproteobacteria,1KJF3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Alkyl hydroperoxide reductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
TLS2_k127_4337909_1	420662.Mpe_A1496	5.987e-158	501.0	COG0492@1|root,COG0492@2|Bacteria,1MW14@1224|Proteobacteria,2VGZS@28216|Betaproteobacteria,1KJ6X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Ferredoxin--NADP reductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
TLS2_k127_4337909_3	987059.RBXJA2T_17322	5.584e-59	207.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2VSJ0@28216|Betaproteobacteria,1KM2U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4,Fer4_10,Fer4_4
TLS2_k127_4337909_2	1265502.KB905931_gene1737	2.071e-105	351.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,4AAU2@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
TLS2_k127_4337909_0	1265502.KB905931_gene1738	1.988e-188	597.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2VHYV@28216|Betaproteobacteria,4A9K7@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU,GTP_EFTU_D2
TLS2_k127_4340407_1	1265502.KB905931_gene1615	4.496e-178	561.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,4AB5M@80864|Comamonadaceae	28216|Betaproteobacteria	T	TIGRFAM nitrogen regulation protein NR(I)	ntrC	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS2_k127_4340407_2	987059.RBXJA2T_16857	3.275e-169	561.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2VJN7@28216|Betaproteobacteria,1KJWU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
TLS2_k127_4340407_3	983917.RGE_14380	1.699e-48	181.0	2BWQ4@1|root,32QZV@2|Bacteria,1MZQ9@1224|Proteobacteria,2VSNR@28216|Betaproteobacteria,1KM87@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
TLS2_k127_4340407_0	864051.BurJ1DRAFT_1439	1.313e-314	963.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria,1KJNG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	glutamine synthetase	glnA	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360	5.4.4.3,6.3.1.2	ko:K01915,ko:K20712	ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253,R06988,R09284	RC00010,RC01754,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
TLS2_k127_4340407_4	987059.RBXJA2T_16842	7.673e-33	128.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2VHTD@28216|Betaproteobacteria,1KK1N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Probable molybdopterin binding domain	yfaY	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
TLS2_k127_4368110_5	983917.RGE_46940	2.647e-51	186.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,1KKP8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
TLS2_k127_4368110_3	987059.RBXJA2T_07558	1.717e-99	331.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2VIBH@28216|Betaproteobacteria,1KKGC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	UPF0056 inner membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
TLS2_k127_4368110_0	864051.BurJ1DRAFT_5007	1.139e-284	881.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2VI6F@28216|Betaproteobacteria,1KJR1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the GMC oxidoreductase family	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
TLS2_k127_4368110_2	987059.RBXJA2T_07568	7.802e-113	370.0	COG1639@1|root,COG1639@2|Bacteria,1PQZH@1224|Proteobacteria,2VQK4@28216|Betaproteobacteria,1KKZB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
TLS2_k127_4368110_1	987059.RBXJA2T_07573	5.01e-265	827.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VMJK@28216|Betaproteobacteria,1KNFI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
TLS2_k127_4368110_6	1538295.JY96_14600	3.943e-45	167.0	2DM6D@1|root,31WQ8@2|Bacteria,1MZ7P@1224|Proteobacteria,2VUHB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4368110_4	1123504.JQKD01000053_gene4354	2.242e-64	225.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2VIRU@28216|Betaproteobacteria,4AC6I@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Ornithine cyclodeaminase mu-crystallin	-	-	1.5.1.1,4.3.1.12	ko:K01750,ko:K19743	ko00310,ko00330,ko00960,ko01100,ko01110,ko01130,ko01230,map00310,map00330,map00960,map01100,map01110,map01130,map01230	-	R00671,R01246,R01249,R02201,R02203	RC00135,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
TLS2_k127_4376474_6	1230476.C207_05763	6.124e-31	128.0	COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,2TUE7@28211|Alphaproteobacteria,3JXD9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS2_k127_4376474_5	330214.NIDE2126	8.212e-40	160.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	yezE	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
TLS2_k127_4376474_7	1415780.JPOG01000001_gene462	1.113e-21	100.0	2E4H4@1|root,32ZC8@2|Bacteria,1N7UT@1224|Proteobacteria,1SPZ7@1236|Gammaproteobacteria,1XAV1@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4376474_3	981369.JQMJ01000004_gene1287	8.775e-54	196.0	COG1335@1|root,COG1335@2|Bacteria,2I9AW@201174|Actinobacteria,2NHVB@228398|Streptacidiphilus	201174|Actinobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
TLS2_k127_4376474_4	1003200.AXXA_30027	2.609e-47	184.0	COG0596@1|root,COG0596@2|Bacteria,1REZX@1224|Proteobacteria,2VUNN@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
TLS2_k127_4376474_1	1279017.AQYJ01000028_gene2525	4.908e-90	308.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS2_k127_4376474_2	509190.Cseg_2321	1.528e-83	287.0	2919Q@1|root,2ZNWS@2|Bacteria,1NAF5@1224|Proteobacteria,2U3AC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	MA20_20955	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4376474_0	543728.Vapar_0971	2.884e-112	365.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,4A9T5@80864|Comamonadaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K07788,ko:K07789	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
TLS2_k127_439181_1	983917.RGE_09520	5.209e-89	295.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,1KKFN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
TLS2_k127_439181_0	987059.RBXJA2T_14276	6.435e-199	628.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,1KJE5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
TLS2_k127_439181_2	365046.Rta_09700	8.487e-24	116.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria,4AB8T@80864|Comamonadaceae	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
TLS2_k127_4400596_3	983917.RGE_16030	4.241e-21	94.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,2VQGS@28216|Betaproteobacteria,1KKKN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0502 family	yceH	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
TLS2_k127_4400596_2	987059.RBXJA2T_13194	2.212e-85	286.0	COG2197@1|root,COG2197@2|Bacteria,1RAAY@1224|Proteobacteria,2VQ17@28216|Betaproteobacteria,1KKIX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_9
TLS2_k127_4400596_0	1538295.JY96_00785	7.526e-120	388.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2VHFT@28216|Betaproteobacteria,1KJX8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	TIGRFAM 3-oxoacid CoA-transferase, A subunit	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
TLS2_k127_4400596_1	420662.Mpe_A1457	1.03e-119	391.0	COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,2VII6@28216|Betaproteobacteria,1KKFA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	3-oxoacid CoA-transferase, B subunit	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
TLS2_k127_4416774_3	983917.RGE_16030	8.535e-61	213.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,2VQGS@28216|Betaproteobacteria,1KKKN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0502 family	yceH	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
TLS2_k127_4416774_0	987059.RBXJA2T_13174	2.634e-135	434.0	COG1028@1|root,COG1028@2|Bacteria,1MXWI@1224|Proteobacteria,2VJIU@28216|Betaproteobacteria,1KJR4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	short-chain dehydrogenase	gno2	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS2_k127_4416774_1	987059.RBXJA2T_14216	8.664e-92	313.0	COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,2VIQD@28216|Betaproteobacteria,1KJEF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS2_k127_4416774_2	983917.RGE_14550	3.882e-77	266.0	COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,2VJAI@28216|Betaproteobacteria,1KJGP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS2_k127_4427249_0	338969.Rfer_3883	4.016e-167	533.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2VHIM@28216|Betaproteobacteria,4ABP6@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Ornithine cyclodeaminase mu-crystallin	arcB	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
TLS2_k127_4427249_1	338969.Rfer_3882	8.11e-73	247.0	COG1522@1|root,COG1522@2|Bacteria,1MZ9D@1224|Proteobacteria,2VR5I@28216|Betaproteobacteria,4AEKD@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
TLS2_k127_4427249_2	1268622.AVS7_02131	1.983e-17	91.0	COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,2VJ19@28216|Betaproteobacteria,4ABCT@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the hyi family	hyi	-	5.3.1.22,5.3.1.35	ko:K01816,ko:K22131	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
TLS2_k127_4427453_4	305700.B447_04943	3.256e-20	97.0	2DNNG@1|root,32Y9C@2|Bacteria,1N8A7@1224|Proteobacteria,2VWN2@28216|Betaproteobacteria,2KZ2D@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4427453_7	595537.Varpa_2016	5.876e-11	71.0	2ECIJ@1|root,336GQ@2|Bacteria,1NFBI@1224|Proteobacteria,2VYFZ@28216|Betaproteobacteria,4AI8J@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4427453_6	1219031.BBJR01000065_gene1151	4.664e-12	72.0	2CIBZ@1|root,2ZH0V@2|Bacteria,1PBAQ@1224|Proteobacteria,2W5YZ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4427453_1	1219031.BBJR01000065_gene1150	2.607e-166	529.0	28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2VPRP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF4043)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4043
TLS2_k127_4427453_8	118005.AWNK01000004_gene1140	7.064e-08	64.0	2ETDW@1|root,33KXP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4427453_3	40215.BBOS01000001_gene743	2.077e-37	145.0	2EPAR@1|root,33GXH@2|Bacteria,1N7YQ@1224|Proteobacteria,1STFM@1236|Gammaproteobacteria,3NJS2@468|Moraxellaceae	1236|Gammaproteobacteria	S	RyR domain	-	-	-	-	-	-	-	-	-	-	-	-	RyR
TLS2_k127_4427453_0	629265.PMA4326_09815	1.277e-203	655.0	COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria	1224|Proteobacteria	NU	Phage P22-like portal protein	-	-	-	-	-	-	-	-	-	-	-	-	P22_portal
TLS2_k127_4427453_2	1279038.KB907345_gene3478	3.091e-54	198.0	COG0507@1|root,COG5362@1|root,COG0507@2|Bacteria,COG5362@2|Bacteria,1R90H@1224|Proteobacteria,2U236@28211|Alphaproteobacteria,2JUGR@204441|Rhodospirillales	204441|Rhodospirillales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4438200_5	987059.RBXJA2T_06040	1.76e-39	151.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,2VJUC@28216|Betaproteobacteria,1KKNU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
TLS2_k127_4438200_2	1265502.KB905932_gene1825	2.725e-149	477.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2VHYP@28216|Betaproteobacteria,4AACD@80864|Comamonadaceae	28216|Betaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
TLS2_k127_4438200_3	983917.RGE_40990	1.059e-109	359.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2VI4M@28216|Betaproteobacteria,1KIXX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
TLS2_k127_4438200_4	983917.RGE_41000	2.068e-44	166.0	COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria,2VWEY@28216|Betaproteobacteria,1KMG1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Domain of unknown function (DUF4845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4845
TLS2_k127_4438200_1	987059.RBXJA2T_06060	8.253e-163	518.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria,1KJ5S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
TLS2_k127_4438200_0	395495.Lcho_0601	0.0	1110.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,1KJPB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
TLS2_k127_4477731_1	1504672.669784757	3.485e-148	472.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,4ABEH@80864|Comamonadaceae	28216|Betaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
TLS2_k127_4477731_0	595537.Varpa_0290	5.704e-150	476.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,4AAJ8@80864|Comamonadaceae	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
TLS2_k127_4504175_0	864051.BurJ1DRAFT_3463	7.423e-76	269.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,2WHQF@28216|Betaproteobacteria,1KM9W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
TLS2_k127_4504175_1	864051.BurJ1DRAFT_3461	2.119e-59	212.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS2_k127_4506059_2	987059.RBXJA2T_03578	9.719e-23	100.0	2EMEQ@1|root,33F3I@2|Bacteria,1NGX3@1224|Proteobacteria,2VY0E@28216|Betaproteobacteria,1KMUE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4506059_1	983917.RGE_10100	1.287e-157	503.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria,1KIUC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
TLS2_k127_4506059_3	420662.Mpe_A1438	1.418e-13	83.0	2EJUE@1|root,33DJ2@2|Bacteria,1NJVX@1224|Proteobacteria,2VY2W@28216|Betaproteobacteria,1KMQ6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4506059_0	395495.Lcho_3847	1.721e-266	831.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,2VHGJ@28216|Betaproteobacteria,1KIZA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	fad dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	Amino_oxidase,Pyr_redox_2
TLS2_k127_4531670_4	864051.BurJ1DRAFT_1480	1.105e-17	84.0	COG0502@1|root,COG0502@2|Bacteria,1QWVD@1224|Proteobacteria,2WH18@28216|Betaproteobacteria,1KMSG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS2_k127_4531670_1	864051.BurJ1DRAFT_1481	1.178e-85	287.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
TLS2_k127_4531670_0	1268622.AVS7_04004	7.096e-171	545.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2VI98@28216|Betaproteobacteria,4AAQC@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM aldo keto reductase	mocA	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS2_k127_4531670_2	926550.CLDAP_36650	1.371e-81	281.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
TLS2_k127_4545973_1	983917.RGE_31850	1.839e-205	648.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria,1KJPR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
TLS2_k127_4545973_2	983917.RGE_31860	7.457e-130	418.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2VH04@28216|Betaproteobacteria,1KJZH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS2_k127_4545973_3	983917.RGE_31870	1.135e-18	88.0	2EFX9@1|root,339PI@2|Bacteria,1NI0D@1224|Proteobacteria,2VU0U@28216|Betaproteobacteria,1KMSH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4545973_4	1538295.JY96_20600	2.277e-13	73.0	COG3198@1|root,COG3198@2|Bacteria,1NGZS@1224|Proteobacteria,2VYSU@28216|Betaproteobacteria,1KMRH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
TLS2_k127_4545973_0	864051.BurJ1DRAFT_3499	2.892e-232	726.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria,1KIYJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	cytochrome C oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
TLS2_k127_4555559_3	987059.RBXJA2T_04778	1.4e-77	261.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2VIT5@28216|Betaproteobacteria,1KKBA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
TLS2_k127_4555559_2	1538295.JY96_03595	9.267e-97	333.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VJCP@28216|Betaproteobacteria,1KJ7C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PFAM SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
TLS2_k127_4555559_0	323848.Nmul_A1487	6.66e-278	866.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VIAP@28216|Betaproteobacteria,37259@32003|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter	-	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS2_k127_4555559_5	317655.Sala_2692	2.799e-53	194.0	COG1309@1|root,COG1309@2|Bacteria,1N6WG@1224|Proteobacteria,2UG93@28211|Alphaproteobacteria,2K7S9@204457|Sphingomonadales	204457|Sphingomonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
TLS2_k127_4555559_4	1265490.JHVY01000015_gene128	9.196e-74	261.0	COG1619@1|root,COG1619@2|Bacteria,1RDGY@1224|Proteobacteria,1T05T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	peptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
TLS2_k127_4555559_1	987059.RBXJA2T_06275	6.755e-109	361.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2VGZK@28216|Betaproteobacteria,1KJ3Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	phosphoribosylaminoimidazole-succinocarboxamide synthase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
TLS2_k127_4555559_6	1123393.KB891316_gene1707	1.023e-35	144.0	COG3608@1|root,COG3608@2|Bacteria,1PBZ4@1224|Proteobacteria,2VMFQ@28216|Betaproteobacteria,1KSB2@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
TLS2_k127_4590060_1	1121116.KB894766_gene367	4.623e-82	280.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2WGFS@28216|Betaproteobacteria,4AA27@80864|Comamonadaceae	28216|Betaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS2_k127_4590060_0	1223521.BBJX01000001_gene842	1.021e-159	529.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,4ABB4@80864|Comamonadaceae	28216|Betaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10,6.3.2.13	ko:K01929,ko:K15792	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R02788,R04573,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS2_k127_4590060_2	595537.Varpa_0976	4.803e-19	89.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,4ABVH@80864|Comamonadaceae	28216|Betaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
TLS2_k127_4620220_1	358220.C380_13790	1.046e-41	171.0	COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,2VRJA@28216|Betaproteobacteria,4AE31@80864|Comamonadaceae	28216|Betaproteobacteria	S	17 kDa surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
TLS2_k127_4620220_0	887062.HGR_02992	1.731e-121	393.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,2VHGJ@28216|Betaproteobacteria,4AAYD@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	Amino_oxidase,Pyr_redox_2
TLS2_k127_4651655_0	983917.RGE_33210	6.605e-233	727.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria,1KJ1R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TLS2_k127_4651655_2	987059.RBXJA2T_09692	6e-115	377.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria,1KJ9J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
TLS2_k127_4651655_1	983917.RGE_33230	3.055e-212	661.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria,1KJGN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
TLS2_k127_4656803_3	983917.RGE_08380	8.426e-10	60.0	2CEXV@1|root,32S0S@2|Bacteria,1MZKB@1224|Proteobacteria,2VU8J@28216|Betaproteobacteria,1KMC0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Type II secretion system protein B	gspB	-	-	ko:K02451	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	T2SSB
TLS2_k127_4656803_2	76114.ebA4328	4.955e-95	328.0	COG3420@1|root,COG3420@2|Bacteria,1R5QH@1224|Proteobacteria,2VMF9@28216|Betaproteobacteria,2KVT0@206389|Rhodocyclales	206389|Rhodocyclales	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4656803_1	157072.XP_008862672.1	6.329e-180	570.0	COG0626@1|root,KOG0053@2759|Eukaryota	2759|Eukaryota	E	cystathionine gamma-synthase activity	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
TLS2_k127_4656803_0	987059.RBXJA2T_00995	8.104e-241	749.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2VHS1@28216|Betaproteobacteria,1KJDH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
TLS2_k127_4662456_3	987059.RBXJA2T_11782	1.045e-49	179.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2VHF1@28216|Betaproteobacteria,1KIUY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
TLS2_k127_4662456_0	1538295.JY96_03860	1.474e-108	360.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2VHZ0@28216|Betaproteobacteria,1KJJZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
TLS2_k127_4662456_1	420662.Mpe_A1018	1.325e-86	288.0	COG0346@1|root,COG0346@2|Bacteria,1RA9H@1224|Proteobacteria,2VQ0D@28216|Betaproteobacteria,1KKQ1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase_4
TLS2_k127_4662456_2	987059.RBXJA2T_03391	1.449e-82	278.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2VH59@28216|Betaproteobacteria,1KJ3N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Biotin carboxylase C-terminal domain	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
TLS2_k127_4666281_1	983917.RGE_08270	1.316e-37	144.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,2VKZ3@28216|Betaproteobacteria,1KKK7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
TLS2_k127_4666281_0	29581.BW37_03398	0.0	1218.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,4723Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	GXGXG motif	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
TLS2_k127_4676831_0	338969.Rfer_1882	8.322e-112	376.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,4AGEM@80864|Comamonadaceae	28216|Betaproteobacteria	M	OmpA-like transmembrane domain	rmpM	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,SmpA_OmlA
TLS2_k127_4676831_1	1341155.FSS13T_07960	4.651e-36	140.0	COG4412@1|root,COG4932@1|root,COG5184@1|root,COG4412@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,4NK5Z@976|Bacteroidetes,1IKKZ@117743|Flavobacteriia,2NTPP@237|Flavobacterium	976|Bacteroidetes	DMZ	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494
TLS2_k127_4694748_0	1223521.BBJX01000004_gene2578	6.618e-129	423.0	28H8Z@1|root,2ZC05@2|Bacteria,1RBDW@1224|Proteobacteria,2VRPB@28216|Betaproteobacteria,4AEA6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
TLS2_k127_4694748_1	1100721.ALKO01000003_gene2434	3.323e-49	176.0	2B3E9@1|root,31W34@2|Bacteria,1MZ95@1224|Proteobacteria,2VSQX@28216|Betaproteobacteria,4AEPW@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4694748_2	398767.Glov_2076	7.775e-31	127.0	COG0515@1|root,COG0515@2|Bacteria	398767.Glov_2076|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_469892_2	365044.Pnap_1316	3.838e-100	333.0	COG0664@1|root,COG0664@2|Bacteria,1RAF3@1224|Proteobacteria,2VQIC@28216|Betaproteobacteria,4AE0D@80864|Comamonadaceae	28216|Betaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
TLS2_k127_469892_1	1120999.JONM01000001_gene1506	3.035e-125	407.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2VH1V@28216|Betaproteobacteria,2KSEH@206351|Neisseriales	206351|Neisseriales	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
TLS2_k127_469892_3	983917.RGE_37690	2.578e-82	287.0	COG2885@1|root,COG2885@2|Bacteria,1REH1@1224|Proteobacteria,2VRF2@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398,OmpA
TLS2_k127_469892_4	983917.RGE_37680	6.341e-20	98.0	2DR1X@1|root,339TY@2|Bacteria,1R3GV@1224|Proteobacteria,2VVPI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398
TLS2_k127_469892_0	1163409.UUA_01624	4.596e-129	424.0	COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,1S0KD@1236|Gammaproteobacteria,1X3ST@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
TLS2_k127_4729976_4	983917.RGE_33880	0.0004827	43.0	2EC30@1|root,3361Z@2|Bacteria,1NB2T@1224|Proteobacteria,2VW1B@28216|Betaproteobacteria,1KMSJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4729976_0	987059.RBXJA2T_09337	2.761e-156	497.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2VH2I@28216|Betaproteobacteria,1KJIP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
TLS2_k127_4729976_1	987059.RBXJA2T_09332	1.392e-101	338.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2VNM5@28216|Betaproteobacteria,1KMA0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4729976_3	1265502.KB905975_gene589	1.397e-33	130.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria,4AEUE@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	sirA	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
TLS2_k127_4729976_2	987059.RBXJA2T_09277	7.597e-93	306.0	COG2816@1|root,COG2816@2|Bacteria,1REUJ@1224|Proteobacteria,2VRF4@28216|Betaproteobacteria,1KKP4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Nudix N-terminal	-	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,Nudix_N_2
TLS2_k127_4741668_7	864051.BurJ1DRAFT_4153	7.16e-22	96.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VIPS@28216|Betaproteobacteria,1KJQI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CH	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	ubiF	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,SE
TLS2_k127_4741668_4	987059.RBXJA2T_00050	1.062e-99	331.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,2VIHV@28216|Betaproteobacteria,1KJWI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
TLS2_k127_4741668_6	983917.RGE_41630	2.071e-71	255.0	COG3170@1|root,COG3170@2|Bacteria,1MWZB@1224|Proteobacteria,2VNBQ@28216|Betaproteobacteria,1KK1P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
TLS2_k127_4741668_3	987059.RBXJA2T_06725	5.663e-128	417.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2VJVA@28216|Betaproteobacteria,1KJJT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	paaF	-	4.2.1.17	ko:K01692,ko:K01715,ko:K07534	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01220,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212,map01220	M00032,M00087,M00540	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R05600,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02034,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
TLS2_k127_4741668_0	983917.RGE_41580	9.666e-282	872.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,1KJZM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
TLS2_k127_4741668_1	987059.RBXJA2T_06710	2.089e-204	638.0	COG0673@1|root,COG0673@2|Bacteria,1MUP0@1224|Proteobacteria,2VMEP@28216|Betaproteobacteria,1KITQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	bplA	-	1.1.1.335	ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS2_k127_4741668_5	987059.RBXJA2T_06705	1.094e-97	325.0	COG0110@1|root,COG0110@2|Bacteria,1MZV9@1224|Proteobacteria,2VN51@28216|Betaproteobacteria,1KKI2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	bplB	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep
TLS2_k127_4741668_2	983917.RGE_41550	4.592e-184	585.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,1KK9Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	wlbC	-	2.6.1.98	ko:K13017	ko00520,map00520	-	R10141	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
TLS2_k127_4752304_3	395495.Lcho_3984	9.433e-53	188.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2VU93@28216|Betaproteobacteria,1KM89@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
TLS2_k127_4752304_2	420662.Mpe_A3205	6.63e-57	203.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,1KKZ9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
TLS2_k127_4752304_1	983917.RGE_42250	1.974e-58	205.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,1KKUJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
TLS2_k127_4752304_0	1538295.JY96_07320	1.611e-104	350.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VISB@28216|Betaproteobacteria,1KJKR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Biotin carboxylase	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
TLS2_k127_4754788_1	76114.ebA4264	5.898e-92	305.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VHM2@28216|Betaproteobacteria,2KVFD@206389|Rhodocyclales	206389|Rhodocyclales	M	PEP-CTERM exosortase 1-associated glycosyltransferase, Daro_2409 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
TLS2_k127_4754788_2	118161.KB235916_gene6665	8.971e-38	147.0	COG3744@1|root,COG3744@2|Bacteria,1G6UW@1117|Cyanobacteria,3VMTU@52604|Pleurocapsales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
TLS2_k127_4754788_0	983917.RGE_04200	4.864e-230	716.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria,1KJWB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Asparagine synthase, glutamine-hydrolyzing	asnB1	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS2_k127_4764425_0	987059.RBXJA2T_01055	3.064e-169	538.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,1KK3W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
TLS2_k127_4764425_1	983917.RGE_08260	2.688e-89	304.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2VI7B@28216|Betaproteobacteria,1KJXB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
TLS2_k127_4774411_4	1163617.SCD_n01211	5.978e-49	178.0	COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,2VN4W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	DMSO reductase anchor subunit (DmsC)	dmsC	-	-	ko:K21309	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	DmsC
TLS2_k127_4774411_1	864051.BurJ1DRAFT_3310	1.141e-132	436.0	COG0730@1|root,COG0730@2|Bacteria,1Q05V@1224|Proteobacteria,2VW5H@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS2_k127_4774411_5	864051.BurJ1DRAFT_3309	3.896e-42	158.0	2DDIC@1|root,32U1K@2|Bacteria,1NDK2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4774411_3	864051.BurJ1DRAFT_3308	1.624e-81	287.0	COG0589@1|root,COG0589@2|Bacteria,1NBKV@1224|Proteobacteria	1224|Proteobacteria	T	PFAM UspA domain protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE,Usp
TLS2_k127_4774411_2	864051.BurJ1DRAFT_3307	2.464e-102	336.0	COG0599@1|root,COG2146@1|root,COG0599@2|Bacteria,COG2146@2|Bacteria,1RCCG@1224|Proteobacteria	1224|Proteobacteria	P	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Rieske
TLS2_k127_4774411_0	864051.BurJ1DRAFT_3306	2.4e-137	458.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2VKWX@28216|Betaproteobacteria,1KKAX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
TLS2_k127_4813629_2	987059.RBXJA2T_09182	6.289e-62	216.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,1KJ8Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	DDE_Tnp_ISL3,FA_desaturase
TLS2_k127_4813629_0	420662.Mpe_A1114	1.013e-196	623.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2VI1D@28216|Betaproteobacteria,1KIZZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB_2	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
TLS2_k127_4813629_1	983917.RGE_34200	1.496e-94	314.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2VJG8@28216|Betaproteobacteria,1KJFH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
TLS2_k127_4815519_0	1198452.Jab_2c34900	6.443e-179	579.0	COG1216@1|root,COG3914@1|root,COG4976@1|root,COG1216@2|Bacteria,COG3914@2|Bacteria,COG4976@2|Bacteria,1QU3U@1224|Proteobacteria,2WH8E@28216|Betaproteobacteria,4796J@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,Glycos_transf_2,Methyltransf_23,TPR_16,TPR_8
TLS2_k127_483032_4	983917.RGE_10520	1.443e-65	228.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,2VSGG@28216|Betaproteobacteria,1KKTI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Starvation protein B	sspB	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
TLS2_k127_483032_1	987059.RBXJA2T_06980	9.826e-128	409.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2VIAW@28216|Betaproteobacteria,1KKCU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Glutathione S-transferase	sspA	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_C_2,GST_N,GST_N_3
TLS2_k127_483032_2	1265502.KB905938_gene2467	1.042e-117	397.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,4A9JZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	cytochrome c1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
TLS2_k127_483032_0	983917.RGE_10490	5.696e-254	793.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,1KK8K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
TLS2_k127_483032_3	358220.C380_04500	9.561e-102	336.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria,4AAIY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
TLS2_k127_483032_5	987059.RBXJA2T_06960	6.774e-61	221.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2VT9K@28216|Betaproteobacteria,1KKUV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
TLS2_k127_483032_6	987059.RBXJA2T_06955	4.044e-28	115.0	COG3170@1|root,COG3170@2|Bacteria,1QV1N@1224|Proteobacteria,2WGRZ@28216|Betaproteobacteria,1KJQ0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
TLS2_k127_483722_2	395495.Lcho_3733	7.238e-67	230.0	COG3381@1|root,COG3381@2|Bacteria,1MWWM@1224|Proteobacteria,2VJ39@28216|Betaproteobacteria,1KKHR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Nitrate reductase delta subunit	torD	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
TLS2_k127_483722_1	864051.BurJ1DRAFT_1333	5.146e-97	321.0	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,2VQR2@28216|Betaproteobacteria,1KKJ4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
TLS2_k127_483722_0	395495.Lcho_3735	8.754e-212	670.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KJH0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS2_k127_4886129_3	338969.Rfer_4077	0.0001707	49.0	COG4654@1|root,COG4654@2|Bacteria,1MZJM@1224|Proteobacteria,2VV99@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Pfam cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
TLS2_k127_4886129_2	1304883.KI912532_gene1813	1.025e-06	56.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,2KX86@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
TLS2_k127_4886129_0	290397.Adeh_1659	5.863e-143	467.0	COG3005@1|root,COG3005@2|Bacteria,1R956@1224|Proteobacteria,42Q0X@68525|delta/epsilon subdivisions,2WMHI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
TLS2_k127_4886129_1	404589.Anae109_3084	6.77e-68	248.0	2C6TZ@1|root,32RHS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4913788_2	395495.Lcho_0322	6.176e-59	205.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,2VMPA@28216|Betaproteobacteria,1KKGN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Methionine biosynthesis protein MetW	metW	-	-	-	-	-	-	-	-	-	-	-	MetW
TLS2_k127_4913788_1	1265502.KB905930_gene1433	3.923e-92	326.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJNX@28216|Betaproteobacteria,4AJWE@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_7,PAS_8,PAS_9,PilJ,Response_reg
TLS2_k127_4913788_0	987059.RBXJA2T_00679	0.0	1010.0	COG2866@1|root,COG2866@2|Bacteria,1R586@1224|Proteobacteria	1224|Proteobacteria	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
TLS2_k127_4913788_3	935567.JAES01000017_gene2408	5.625e-31	126.0	COG3279@1|root,COG3279@2|Bacteria,1R9Q4@1224|Proteobacteria,1SYFA@1236|Gammaproteobacteria,1X395@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS2_k127_4913913_0	614083.AWQR01000018_gene1915	5.081e-180	568.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VHND@28216|Betaproteobacteria,4ADJK@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033,ko:K12369	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
TLS2_k127_4913913_1	296591.Bpro_2813	4.217e-153	489.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2VHX8@28216|Betaproteobacteria,4AD2R@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	dppC	-	-	ko:K02034,ko:K12370	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
TLS2_k127_4913913_2	1504672.669787118	4.188e-149	486.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2W0NK@28216|Betaproteobacteria,4AA2A@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	dppD	-	-	ko:K02031,ko:K12371	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
TLS2_k127_4913913_3	338969.Rfer_1950	1.927e-129	417.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2W19X@28216|Betaproteobacteria,4AC9I@80864|Comamonadaceae	28216|Betaproteobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	dppF	-	-	ko:K12372	ko02010,map02010	M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
TLS2_k127_4917067_0	365046.Rta_09700	1.33e-161	518.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria,4AB8T@80864|Comamonadaceae	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
TLS2_k127_4917067_1	1286631.X805_15990	3.868e-137	445.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria,1KJRM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS2_k127_4921813_2	864051.BurJ1DRAFT_0210	3.932e-102	346.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2VIQM@28216|Betaproteobacteria,1KN95@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
TLS2_k127_4921813_0	338969.Rfer_2799	0.0	1077.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2VIEB@28216|Betaproteobacteria,4A9VY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
TLS2_k127_4921813_1	864051.BurJ1DRAFT_0212	6.142e-206	645.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,1KKEG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADPH-dependent glutamate synthase beta	korC	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
TLS2_k127_4925658_1	983917.RGE_42440	5.491e-168	533.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria,1KJST@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TLS2_k127_4925658_0	983917.RGE_42430	2.214e-217	681.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria,1KKAQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
TLS2_k127_4925658_2	987059.RBXJA2T_11683	5.43e-13	70.0	2ECC1@1|root,336AE@2|Bacteria,1N89B@1224|Proteobacteria,2VXK8@28216|Betaproteobacteria,1KMMY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_4925810_2	414684.RC1_2536	1.127e-43	166.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,2TUG6@28211|Alphaproteobacteria,2JU86@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS2_k127_4925810_1	987059.RBXJA2T_06625	2.41e-106	357.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,2VMU1@28216|Betaproteobacteria,1KMEA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	PFAM Glycosyl transferases group 1	epsN	-	2.4.1.348	ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS2_k127_4925810_0	987059.RBXJA2T_06605	3.874e-191	610.0	COG0438@1|root,COG0438@2|Bacteria,1R80Y@1224|Proteobacteria,2VPZI@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
TLS2_k127_4925810_3	420662.Mpe_A3464	9.237e-30	124.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Laminin_G_3,Lipase_GDSL_2
TLS2_k127_4994946_0	987059.RBXJA2T_08385	1.284e-284	884.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,1KIZX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
TLS2_k127_4994946_1	983917.RGE_24020	1.644e-18	86.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,2VIPK@28216|Betaproteobacteria,1KK6C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	prmB	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
TLS2_k127_4998954_0	987059.RBXJA2T_04028	0.0	1224.0	COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,2VI2M@28216|Betaproteobacteria,1KKC4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	PrkA AAA domain	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
TLS2_k127_4998954_2	614083.AWQR01000025_gene3748	2.183e-144	467.0	COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2VKPZ@28216|Betaproteobacteria,4AB3E@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS2_k127_4998954_3	1265502.KB905947_gene1086	3.153e-126	412.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2VIG0@28216|Betaproteobacteria,4AAXW@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
TLS2_k127_4998954_4	864051.BurJ1DRAFT_0054	7.417e-71	253.0	COG3545@1|root,COG3545@2|Bacteria,1RDB7@1224|Proteobacteria,2VQ1M@28216|Betaproteobacteria,1KKZW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Alpha beta hydrolase	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
TLS2_k127_4998954_1	983917.RGE_00600	9.928e-148	473.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,1KJWY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh
TLS2_k127_5015144_3	1123073.KB899241_gene3109	2.499e-07	53.0	COG3568@1|root,COG3568@2|Bacteria,1PPNP@1224|Proteobacteria,1S9D7@1236|Gammaproteobacteria,1X46I@135614|Xanthomonadales	135614|Xanthomonadales	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS2_k127_5015144_1	314285.KT71_17656	5.963e-124	408.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RRXR@1236|Gammaproteobacteria,1JAET@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
TLS2_k127_5015144_0	983917.RGE_46170	3.467e-151	483.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,2VHQY@28216|Betaproteobacteria,1KIZ2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulator	cbl	-	-	ko:K13634,ko:K13635	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
TLS2_k127_5015144_2	1198452.Jab_1c09500	2.448e-20	96.0	COG1629@1|root,COG1629@2|Bacteria,1MV8W@1224|Proteobacteria,2WBFZ@28216|Betaproteobacteria,475R2@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
TLS2_k127_5024213_3	626418.bglu_1g21920	5.382e-25	111.0	2AMYS@1|root,31CVX@2|Bacteria,1Q9RU@1224|Proteobacteria,2W6UM@28216|Betaproteobacteria,1KCRU@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_5024213_0	999541.bgla_2g01410	4.569e-88	304.0	28PW5@1|root,2ZCGI@2|Bacteria,1RB39@1224|Proteobacteria,2WII0@28216|Betaproteobacteria,1K7TY@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_5024213_1	1123487.KB892839_gene178	2.355e-35	137.0	2CU57@1|root,333RB@2|Bacteria,1N95P@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_5024213_2	342113.DM82_3471	2.34e-28	121.0	2E3AP@1|root,32YA7@2|Bacteria,1NA98@1224|Proteobacteria,2WIHD@28216|Betaproteobacteria,1K9Q0@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Killing trait	-	-	-	-	-	-	-	-	-	-	-	-	RebB
TLS2_k127_5040800_3	426114.THI_2267	5.834e-07	52.0	COG1587@1|root,COG1587@2|Bacteria	2|Bacteria	H	uroporphyrinogen-III synthase activity	hemD	GO:0003674,GO:0003824,GO:0004852,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.107,2.5.1.61,4.2.1.75	ko:K01719,ko:K01749,ko:K02496,ko:K13542,ko:K13543	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084,R03165,R03194	RC00003,RC00871,RC01861,RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0187,iSBO_1134.SBO_3815	HEM4,HemX
TLS2_k127_5040800_1	688245.CtCNB1_4397	1.255e-36	139.0	2CC0C@1|root,32RUG@2|Bacteria,1MZVQ@1224|Proteobacteria,2VUAQ@28216|Betaproteobacteria,4AEUG@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3297)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3297
TLS2_k127_5040800_0	1247649.D560_3957	2.118e-167	531.0	COG1064@1|root,COG1064@2|Bacteria,1P0UC@1224|Proteobacteria,2VPCZ@28216|Betaproteobacteria,3T6KZ@506|Alcaligenaceae	28216|Betaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS2_k127_504455_0	983917.RGE_44350	3.132e-220	703.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KJDR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_8,PAS_9,SBP_bac_3
TLS2_k127_504455_2	983917.RGE_44360	3.223e-143	467.0	COG2206@1|root,COG2206@2|Bacteria,1N5T4@1224|Proteobacteria,2VK22@28216|Betaproteobacteria,1KK1A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
TLS2_k127_504455_4	1100721.ALKO01000015_gene1033	1.062e-40	152.0	COG2329@1|root,COG2329@2|Bacteria,1N078@1224|Proteobacteria,2VSX8@28216|Betaproteobacteria,4AER0@80864|Comamonadaceae	28216|Betaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
TLS2_k127_504455_1	93220.LV28_06250	4.976e-191	612.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2VHV4@28216|Betaproteobacteria,1K04S@119060|Burkholderiaceae	28216|Betaproteobacteria	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
TLS2_k127_504455_3	365046.Rta_14610	3.606e-49	181.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,2VU5M@28216|Betaproteobacteria,4AENB@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
TLS2_k127_504499_5	983917.RGE_35390	6.521e-49	179.0	COG2346@1|root,COG2346@2|Bacteria,1RH21@1224|Proteobacteria,2VSUJ@28216|Betaproteobacteria,1KM1R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Bacterial-like globin	yjbI	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
TLS2_k127_504499_1	983917.RGE_35400	1.429e-113	370.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,2VRTK@28216|Betaproteobacteria,1KIZN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Belongs to the ParA family	fleN	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
TLS2_k127_504499_3	987059.RBXJA2T_18523	2.948e-95	321.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VKPP@28216|Betaproteobacteria,1KIUE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
TLS2_k127_504499_0	983917.RGE_35420	6.557e-152	486.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2VKFS@28216|Betaproteobacteria,1KJ0D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
TLS2_k127_504499_2	983917.RGE_35430	1.909e-103	343.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,2VJ1T@28216|Betaproteobacteria,1KJXG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
TLS2_k127_504499_4	987059.RBXJA2T_18538	3.886e-71	242.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2VI13@28216|Betaproteobacteria,1KJEP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
TLS2_k127_5051585_2	864051.BurJ1DRAFT_1560	2.411e-57	207.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,1KJBY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
TLS2_k127_5051585_0	983917.RGE_39090	2.091e-196	618.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,1KJT1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	aminotransferase class I and II	aspC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
TLS2_k127_5051585_1	987059.RBXJA2T_06790	3.638e-67	234.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2VSI6@28216|Betaproteobacteria,1KKV8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
TLS2_k127_5053326_0	395495.Lcho_0750	3.944e-263	821.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,1KK3X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Protein of unknown function (DUF3683)	glpCD	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
TLS2_k127_5056364_1	987059.RBXJA2T_10064	1.535e-63	220.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2VIU0@28216|Betaproteobacteria,1KJ5C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Riboflavin synthase	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
TLS2_k127_5056364_0	864051.BurJ1DRAFT_0188	2.883e-124	406.0	COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,2VIH3@28216|Betaproteobacteria,1KKEN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
TLS2_k127_5056364_2	1538295.JY96_02870	3.58e-43	171.0	COG1538@1|root,COG1538@2|Bacteria,1R8U9@1224|Proteobacteria,2VQKG@28216|Betaproteobacteria,1KKJX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP
TLS2_k127_5063950_4	987059.RBXJA2T_13819	9.703e-37	145.0	COG0042@1|root,COG0042@2|Bacteria,1MUSM@1224|Proteobacteria,2VHWD@28216|Betaproteobacteria,1KJW6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs	dusC	-	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
TLS2_k127_5063950_1	1163408.UU9_11873	9.746e-145	473.0	COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,1RNFI@1236|Gammaproteobacteria,1X54A@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the peptidase M17 family	pepA2	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17
TLS2_k127_5063950_3	864051.BurJ1DRAFT_4480	7.97e-77	278.0	COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,2VSH1@28216|Betaproteobacteria,1KM5M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	SapC	-	-	-	-	-	-	-	-	-	-	-	-	SapC
TLS2_k127_5063950_0	987059.RBXJA2T_13829	4.497e-199	629.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2VHBA@28216|Betaproteobacteria,1KJJI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	CBS domain containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
TLS2_k127_5063950_2	864051.BurJ1DRAFT_4478	2.28e-127	411.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,2VHV6@28216|Betaproteobacteria,1KJHU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
TLS2_k127_5066591_5	987059.RBXJA2T_07788	1.011e-15	79.0	COG1169@1|root,COG1169@2|Bacteria,1MVB7@1224|Proteobacteria,2VQF6@28216|Betaproteobacteria	28216|Betaproteobacteria	HQ	Isochorismate synthase	dhbC	-	5.4.4.2	ko:K01851,ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
TLS2_k127_5066591_1	987059.RBXJA2T_15133	4.693e-147	477.0	COG4448@1|root,COG4448@2|Bacteria,1R4NH@1224|Proteobacteria,2VJES@28216|Betaproteobacteria	28216|Betaproteobacteria	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
TLS2_k127_5066591_2	502025.Hoch_2371	6.195e-58	213.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42SA7@68525|delta/epsilon subdivisions,2WNRU@28221|Deltaproteobacteria,2YU91@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
TLS2_k127_5066591_0	864051.BurJ1DRAFT_0325	8.611e-250	782.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08162,ko:K08226,ko:K16211	-	-	-	-	ko00000,ko02000	2.A.1.2.21,2.A.1.41,2.A.2.6	-	-	MFS_1,PUCC
TLS2_k127_5066591_4	365046.Rta_06890	6.491e-47	170.0	COG1669@1|root,COG1669@2|Bacteria,1N17I@1224|Proteobacteria,2VVYD@28216|Betaproteobacteria,4AEYM@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM DNA polymerase, beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
TLS2_k127_5066591_3	365046.Rta_06900	9.081e-58	206.0	COG2361@1|root,COG2361@2|Bacteria,1RAGS@1224|Proteobacteria,2VQBZ@28216|Betaproteobacteria,4AEQU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
TLS2_k127_5066591_6	1266925.JHVX01000015_gene206	9.551e-05	44.0	COG1203@1|root,COG1203@2|Bacteria,1MVZF@1224|Proteobacteria,2VHZ8@28216|Betaproteobacteria,374G2@32003|Nitrosomonadales	28216|Betaproteobacteria	L	DEAD-like helicases superfamily	-	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
TLS2_k127_5080738_2	983917.RGE_33260	5.455e-53	189.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,2VVP0@28216|Betaproteobacteria,1KKW4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	CRS1_YhbY	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
TLS2_k127_5080738_3	987059.RBXJA2T_09672	3.444e-50	183.0	2AJXH@1|root,32VYF@2|Bacteria,1N37R@1224|Proteobacteria,2VU73@28216|Betaproteobacteria,1KMAB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
TLS2_k127_5080738_1	983917.RGE_33280	2.323e-79	268.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2VQ16@28216|Betaproteobacteria,1KKKH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
TLS2_k127_5080738_0	1095769.CAHF01000011_gene2576	0.0	1558.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,472V3@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
TLS2_k127_5101209_3	983917.RGE_32560	2.906e-25	106.0	COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,2VVSP@28216|Betaproteobacteria,1KMNH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
TLS2_k127_5101209_1	395495.Lcho_2020	2.547e-70	246.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2VRMG@28216|Betaproteobacteria,1KKKE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Molybdopterin biosynthesis MoaE protein	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
TLS2_k127_5101209_2	983917.RGE_32540	2.24e-47	183.0	COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,2VQA1@28216|Betaproteobacteria,1KKWU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Flavin reductase like domain	ntaB	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,IclR
TLS2_k127_5101209_0	864051.BurJ1DRAFT_2507	6.194e-134	431.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,1KJ9T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
TLS2_k127_510234_4	864051.BurJ1DRAFT_1515	5.524e-39	149.0	COG1629@1|root,COG4771@2|Bacteria,1QWIP@1224|Proteobacteria,2VKD5@28216|Betaproteobacteria,1KKH8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
TLS2_k127_510234_3	365046.Rta_13980	6.865e-88	297.0	COG0834@1|root,COG0834@2|Bacteria,1N2RR@1224|Proteobacteria,2VMGM@28216|Betaproteobacteria,4ABY0@80864|Comamonadaceae	28216|Betaproteobacteria	ET	SMART Extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
TLS2_k127_510234_1	987059.RBXJA2T_18718	5.643e-113	372.0	COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,2VI6Y@28216|Betaproteobacteria,1KN0M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Phosphate acyltransferases	yihG	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TLS2_k127_510234_0	1550073.JROH01000027_gene961	2.244e-184	586.0	COG0475@1|root,COG0475@2|Bacteria,1MVGV@1224|Proteobacteria,2U08Q@28211|Alphaproteobacteria,2KCC2@204457|Sphingomonadales	204457|Sphingomonadales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
TLS2_k127_510234_2	107635.AZUO01000001_gene2231	2.951e-98	345.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2TS99@28211|Alphaproteobacteria,36XDN@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Shikimate dehydrogenase substrate binding domain	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
TLS2_k127_510234_5	864051.BurJ1DRAFT_3442	1.255e-34	136.0	COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,2VHD8@28216|Betaproteobacteria,1KJ5F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	May be involved in recombination	rdgC	-	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
TLS2_k127_5146381_4	693444.D782_3620	5.012e-100	336.0	COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,1RPU1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
TLS2_k127_5146381_1	864051.BurJ1DRAFT_4547	0.0	1002.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,1KKEG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADPH-dependent glutamate synthase beta	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2,Pyr_redox_3
TLS2_k127_5146381_3	395495.Lcho_2151	6.315e-192	601.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,2VKQX@28216|Betaproteobacteria,1KJCA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	porB	-	1.2.1.58,1.2.7.1	ko:K00170,ko:K18356	ko00010,ko00020,ko00360,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00360,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R02450,R08034	RC00004,RC00250,RC02742,RC02833,RC02860	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_11,Fer4_6,TPP_enzyme_C
TLS2_k127_5146381_2	395495.Lcho_2150	4.786e-237	738.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,2VJSA@28216|Betaproteobacteria,1KK3S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
TLS2_k127_5146381_7	1123487.KB892840_gene76	9.411e-79	269.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,2VQ8C@28216|Betaproteobacteria,2KVM0@206389|Rhodocyclales	206389|Rhodocyclales	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	padE	-	1.2.1.58	ko:K18357	ko00360,map00360	-	R02450	RC00004,RC02860	br01601,ko00000,ko00001,ko01000	-	-	-	POR
TLS2_k127_5146381_10	572477.Alvin_1033	6.72e-36	138.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,1S9WR@1236|Gammaproteobacteria,1WZ13@135613|Chromatiales	135613|Chromatiales	S	PFAM Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
TLS2_k127_5146381_9	270374.MELB17_04972	1.404e-36	140.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,1SCYV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	TIGRFAM Addiction module antidote protein, HigA	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
TLS2_k127_5146381_5	395495.Lcho_1552	7.487e-93	322.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,1KKAY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Cytochrome c-type biogenesis protein	cycH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2
TLS2_k127_5146381_8	864051.BurJ1DRAFT_2540	8.639e-42	158.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2VU7C@28216|Betaproteobacteria,1KM3E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
TLS2_k127_5146381_6	395495.Lcho_1550	1.251e-81	274.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,1KKN4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CO	Periplasmic protein thiol	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
TLS2_k127_5146381_0	395495.Lcho_1549	0.0	1012.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,1KIYF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	cytochrome C	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
TLS2_k127_5146381_11	1538295.JY96_13785	9.793e-06	48.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria,1KKY8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
TLS2_k127_5174517_2	1265502.KB905984_gene22	1.373e-06	57.0	2CA65@1|root,2Z8DY@2|Bacteria,1MXGI@1224|Proteobacteria,2VM06@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_5174517_3	472175.EL18_02064	0.0001326	51.0	COG2813@1|root,COG2813@2|Bacteria	2|Bacteria	J	rRNA (guanine-N2-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,MMPL,Methyltransf_21,Methyltransf_25,Methyltransf_31
TLS2_k127_5174517_0	1286631.X805_39010	9.77e-53	195.0	COG2433@1|root,COG2433@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
TLS2_k127_5174517_1	1238450.VIBNISOn1_90009	2.676e-11	74.0	COG2433@1|root,COG2433@2|Bacteria,1QYJZ@1224|Proteobacteria,1RUCR@1236|Gammaproteobacteria,1XX4Y@135623|Vibrionales	135623|Vibrionales	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66
TLS2_k127_5188355_4	1123392.AQWL01000004_gene2662	1.264e-174	571.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,2VJ61@28216|Betaproteobacteria,1KSNI@119069|Hydrogenophilales	119069|Hydrogenophilales	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
TLS2_k127_5188355_12	1231185.BAMP01000044_gene1412	1.291e-10	75.0	COG3411@1|root,COG3411@2|Bacteria,1N72B@1224|Proteobacteria,2U7TX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx,CbiX
TLS2_k127_5188355_1	987059.RBXJA2T_10671	2.609e-250	803.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,2VIMP@28216|Betaproteobacteria,1KNGG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
TLS2_k127_5188355_2	987059.RBXJA2T_10676	7.347e-231	722.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KN08@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Sigma-54 interaction domain	atoC	-	-	ko:K02481,ko:K10126,ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	M00504	-	-	ko00000,ko00001,ko00002,ko02022,ko03000	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS2_k127_5188355_0	987059.RBXJA2T_10681	6.386e-262	825.0	COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,2VIZD@28216|Betaproteobacteria,1KN6D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c
TLS2_k127_5188355_3	987059.RBXJA2T_10686	3.023e-193	612.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2VIY4@28216|Betaproteobacteria,1KJZ4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	TIGRFAM sugar transferase, PEP-CTERM system associated	wcaJ	-	2.7.8.40	ko:K21303	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Bac_transf,CoA_binding_3
TLS2_k127_5188355_9	656024.FsymDg_3831	1.082e-31	129.0	COG1848@1|root,COG1848@2|Bacteria,2IKT8@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
TLS2_k127_5188355_8	493475.GARC_5052	2.252e-49	185.0	2DRGA@1|root,33BKP@2|Bacteria,1NGH6@1224|Proteobacteria,1SGNB@1236|Gammaproteobacteria,46C1V@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
TLS2_k127_5188355_7	419947.MRA_2357	5.267e-76	270.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	moeY	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,ThiF
TLS2_k127_5188355_5	987059.RBXJA2T_05373	1.325e-138	446.0	COG0476@1|root,COG0476@2|Bacteria,1QUMS@1224|Proteobacteria,2VN2Y@28216|Betaproteobacteria	28216|Betaproteobacteria	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
TLS2_k127_5188355_6	983917.RGE_04080	4.237e-95	316.0	COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,2VKB3@28216|Betaproteobacteria,1KPKW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	polysaccharide export	wza	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
TLS2_k127_5188355_10	983917.RGE_04090	1.968e-27	113.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2VMDA@28216|Betaproteobacteria,1KJFW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	TIGRFAM polysaccharide chain length determinant protein, PEP-CTERM locus subfamily	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
TLS2_k127_5197249_2	987059.RBXJA2T_13404	2.258e-65	228.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,1KKNH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
TLS2_k127_5197249_1	983917.RGE_46360	4e-323	999.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VH8W@28216|Betaproteobacteria,1KJAS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
TLS2_k127_5197249_0	987059.RBXJA2T_13424	0.0	1650.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,1KJMG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
TLS2_k127_5197249_3	864051.BurJ1DRAFT_4936	1.277e-48	176.0	COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,2VSPC@28216|Betaproteobacteria,1KMDW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	B	SWI complex, BAF60b domains	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
TLS2_k127_5203318_2	358220.C380_02530	8.413e-47	175.0	COG0477@1|root,COG2814@2|Bacteria,1MUXC@1224|Proteobacteria,2VP56@28216|Betaproteobacteria,4ABFY@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS2_k127_5203318_0	1158292.JPOE01000002_gene2832	1.39e-153	497.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VGZM@28216|Betaproteobacteria,1KK1D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ABC transporter	-	-	-	ko:K10111	ko02010,map02010	M00194,M00200,M00204,M00207,M00491	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
TLS2_k127_5203318_1	864051.BurJ1DRAFT_0969	3.413e-149	477.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,2VIBY@28216|Betaproteobacteria,1KJRJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Glycosyl hydrolase family 1	bglA2	-	3.2.1.21,3.2.1.86	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	-	R00026,R00839,R02558,R02887,R02985,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
TLS2_k127_5238842_3	864051.BurJ1DRAFT_0743	9.726e-33	131.0	COG1538@1|root,COG1538@2|Bacteria,1R8U9@1224|Proteobacteria,2VQKG@28216|Betaproteobacteria,1KKJX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP
TLS2_k127_5238842_0	264198.Reut_B3473	4.977e-103	343.0	COG0463@1|root,COG0463@2|Bacteria,1MXQB@1224|Proteobacteria,2W1X4@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyltransferase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
TLS2_k127_5238842_1	1150469.RSPPHO_03145	1.086e-83	286.0	COG0463@1|root,COG0827@1|root,COG4123@1|root,COG5010@1|root,COG0463@2|Bacteria,COG0827@2|Bacteria,COG4123@2|Bacteria,COG5010@2|Bacteria,1PEZZ@1224|Proteobacteria,2UARF@28211|Alphaproteobacteria,2JZR7@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_tranf_2_4
TLS2_k127_5238842_2	637390.AFOH01000025_gene1036	1.326e-46	175.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,1SPE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
TLS2_k127_5253275_4	864051.BurJ1DRAFT_4475	1.421e-68	254.0	COG1309@1|root,COG1309@2|Bacteria,1R52P@1224|Proteobacteria,2VIDN@28216|Betaproteobacteria,1KKHE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Bacterial transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	TetR,TetR_N
TLS2_k127_5253275_0	395495.Lcho_1582	7.62e-146	476.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2VI81@28216|Betaproteobacteria,1KJUB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	ABC transporter	ybhF_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS2_k127_5253275_1	987059.RBXJA2T_15443	2.744e-130	437.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2VH42@28216|Betaproteobacteria,1KJBM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Transport permease protein	yadH	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
TLS2_k127_5253275_5	864051.BurJ1DRAFT_4471	2.872e-37	146.0	COG5007@1|root,COG5007@2|Bacteria,1MZCZ@1224|Proteobacteria,2VU0K@28216|Betaproteobacteria,1KM9Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Belongs to the BolA IbaG family	yrbA	-	-	-	-	-	-	-	-	-	-	-	BolA
TLS2_k127_5253275_3	987059.RBXJA2T_15463	7.282e-105	347.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2VIF9@28216|Betaproteobacteria,1KJJA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
TLS2_k127_5253275_2	987059.RBXJA2T_15468	3.199e-106	362.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,1KJRP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
TLS2_k127_5256207_0	983917.RGE_15020	6e-323	993.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2VHVA@28216|Betaproteobacteria,1KJSQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
TLS2_k127_5256207_2	864051.BurJ1DRAFT_3703	2.367e-151	486.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2VIQF@28216|Betaproteobacteria,1KIY3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
TLS2_k127_5256207_1	864051.BurJ1DRAFT_3705	2.067e-180	569.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2VH7Y@28216|Betaproteobacteria,1KIVQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
TLS2_k127_5265254_4	983917.RGE_00590	4.357e-63	226.0	COG0454@1|root,COG0456@2|Bacteria,1N8AT@1224|Proteobacteria,2WE9A@28216|Betaproteobacteria	28216|Betaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS2_k127_5265254_1	420662.Mpe_A3782	3.539e-133	431.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2VHNK@28216|Betaproteobacteria,1KJC6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Cellulose biosynthesis protein BcsQ	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
TLS2_k127_5265254_3	987059.RBXJA2T_04003	1.895e-82	280.0	COG1280@1|root,COG1280@2|Bacteria,1RA1G@1224|Proteobacteria,2VKHI@28216|Betaproteobacteria,1KKRK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Lysine exporter protein (Lyse ygga)	-	-	-	ko:K11250	-	-	-	-	ko00000,ko02000	2.A.76.1.5	-	-	LysE
TLS2_k127_5265254_2	983917.RGE_00570	3.092e-83	282.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria,1KKMX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
TLS2_k127_5265254_0	983917.RGE_00560	3.365e-321	990.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,1KIWS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
TLS2_k127_5288389_0	983917.RGE_14140	2.072e-247	786.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,1KJDC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Hpt,Response_reg
TLS2_k127_5288389_1	864051.BurJ1DRAFT_3851	1.084e-188	606.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2VI7I@28216|Betaproteobacteria,1KJJE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
TLS2_k127_5288389_2	987059.RBXJA2T_16717	2.182e-67	233.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,2VPZU@28216|Betaproteobacteria,1KKT8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0234 family	yajQ	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
TLS2_k127_5288389_3	983917.RGE_14090	3.04e-52	197.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,2VS6Z@28216|Betaproteobacteria,1KM5G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
TLS2_k127_533156_5	745014.OMB55_00005710	3.735e-16	81.0	COG2050@1|root,COG2050@2|Bacteria,1NGFY@1224|Proteobacteria	1224|Proteobacteria	Q	PFAM thioesterase superfamily	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
TLS2_k127_533156_3	543728.Vapar_5597	9.303e-61	216.0	COG0251@1|root,COG0251@2|Bacteria,1RCX5@1224|Proteobacteria,2VRFR@28216|Betaproteobacteria,4AE10@80864|Comamonadaceae	28216|Betaproteobacteria	J	Endoribonuclease L-PSP	yjgH	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
TLS2_k127_533156_2	1333856.L686_20390	3.861e-153	488.0	COG0583@1|root,COG0583@2|Bacteria,1MV06@1224|Proteobacteria,1RQIH@1236|Gammaproteobacteria,1Z165@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K18900	-	M00698	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	HTH_1,LysR_substrate
TLS2_k127_533156_1	1158292.JPOE01000002_gene2913	8.394e-164	524.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2VHXM@28216|Betaproteobacteria,1KJSV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Luciferase family	limB	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS2_k127_533156_0	1223521.BBJX01000002_gene2856	2.513e-222	703.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2VHBI@28216|Betaproteobacteria,4AGVV@80864|Comamonadaceae	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS2_k127_533156_4	267608.RSc1449	5.034e-47	195.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2VGZ7@28216|Betaproteobacteria,1JZY9@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
TLS2_k127_5353476_2	983917.RGE_46710	3.279e-27	112.0	28NWD@1|root,2ZBU8@2|Bacteria,1RGNH@1224|Proteobacteria,2VRUN@28216|Betaproteobacteria,1KKWS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
TLS2_k127_5353476_0	987059.RBXJA2T_07673	4.203e-261	811.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,1KJ6W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
TLS2_k127_5353476_1	864051.BurJ1DRAFT_4962	1.542e-153	488.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,1KJ1C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
TLS2_k127_5369739_2	983917.RGE_08650	1.707e-63	236.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2VRD3@28216|Betaproteobacteria,1KKUF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
TLS2_k127_5369739_0	983917.RGE_08640	4.61e-142	462.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,1KK4C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
TLS2_k127_5369739_1	420662.Mpe_A0835	1.81e-127	409.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2VI38@28216|Betaproteobacteria,1KK3M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
TLS2_k127_538353_0	365044.Pnap_1565	6.377e-301	932.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria,4A9TW@80864|Comamonadaceae	28216|Betaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
TLS2_k127_538353_1	365044.Pnap_1566	1.799e-55	197.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,4ADXX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
TLS2_k127_5409237_0	1100721.ALKO01000019_gene1385	4.094e-218	685.0	COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,2VH0F@28216|Betaproteobacteria,4AA3S@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM extracellular solute-binding protein family 1	ugpB	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
TLS2_k127_5409237_1	338969.Rfer_1286	1.259e-154	492.0	COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,2VH0I@28216|Betaproteobacteria,4ACEG@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	ugpA	-	-	ko:K05814	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
TLS2_k127_5409237_2	338969.Rfer_1285	6.422e-142	469.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,2VICF@28216|Betaproteobacteria,4AAP2@80864|Comamonadaceae	28216|Betaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	ugpE	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
TLS2_k127_5409237_3	365046.Rta_31300	2.227e-86	289.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VGZM@28216|Betaproteobacteria,4ABN3@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	ugpC	-	3.6.3.20	ko:K05816,ko:K10111,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00198,M00200,M00201,M00204,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.3	-	-	ABC_tran,TOBE_2
TLS2_k127_5409831_0	338969.Rfer_0700	6.859e-203	637.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VK3J@28216|Betaproteobacteria,4ABR6@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Orn DAP Arg decarboxylase 2	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS2_k127_5409831_2	380394.Lferr_0576	8.73e-38	145.0	COG3744@1|root,COG3744@2|Bacteria,1N2T0@1224|Proteobacteria,1S7NW@1236|Gammaproteobacteria,2ND71@225057|Acidithiobacillales	225057|Acidithiobacillales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
TLS2_k127_5409831_3	1218074.BAXZ01000018_gene3705	5.969e-20	91.0	COG4118@1|root,COG4118@2|Bacteria,1P1DQ@1224|Proteobacteria,2VVP8@28216|Betaproteobacteria,1KA2V@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
TLS2_k127_5409831_1	1538295.JY96_15530	5.68e-40	150.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VGZI@28216|Betaproteobacteria,1KJ0H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TLS2_k127_5412180_1	987059.RBXJA2T_17901	1.943e-188	595.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria,1KJGB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
TLS2_k127_5412180_2	864051.BurJ1DRAFT_2958	2.421e-77	279.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria,1KKJ8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Type IV pilus biogenesis stability protein PilW	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
TLS2_k127_5412180_4	864051.BurJ1DRAFT_2957	6.884e-61	222.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,1KM5I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
TLS2_k127_5412180_0	987059.RBXJA2T_17916	7.764e-236	734.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,1KK5J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
TLS2_k127_5412180_3	395495.Lcho_2867	6.84e-71	243.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,1KJ7J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
TLS2_k127_5413614_2	987059.RBXJA2T_00834	3.4e-64	228.0	COG3981@1|root,COG3981@2|Bacteria,1RGGC@1224|Proteobacteria,2VTVY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS2_k127_5413614_1	983917.RGE_34220	1.777e-97	327.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria,1KKS0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Phospholipase/Carboxylesterase	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
TLS2_k127_5413614_3	983917.RGE_34210	8.408e-43	157.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2VIEY@28216|Betaproteobacteria,1KISX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
TLS2_k127_5413614_0	983917.RGE_34210	1.01e-165	525.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2VIEY@28216|Betaproteobacteria,1KISX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
TLS2_k127_5418492_8	987059.RBXJA2T_15693	4.449e-08	59.0	COG2755@1|root,COG2755@2|Bacteria,1RE1B@1224|Proteobacteria,2VUB8@28216|Betaproteobacteria,1KMNC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS2_k127_5418492_4	983917.RGE_09180	2.083e-127	412.0	COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,2VJC1@28216|Betaproteobacteria,1KITU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
TLS2_k127_5418492_2	420662.Mpe_A0416	4.913e-221	692.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,1KJKX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
TLS2_k127_5418492_0	420662.Mpe_A0417	0.0	1342.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VHS7@28216|Betaproteobacteria,1KJZS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	fadB	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
TLS2_k127_5418492_1	420662.Mpe_A0419	0.0	1039.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VIJU@28216|Betaproteobacteria,1KJ7P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
TLS2_k127_5418492_6	987059.RBXJA2T_15658	1.292e-99	329.0	COG1309@1|root,COG1309@2|Bacteria,1R6RX@1224|Proteobacteria,2VKE3@28216|Betaproteobacteria,1KJ4I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	regulatory	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS2_k127_5418492_5	983917.RGE_09120	5.074e-109	354.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2VKQH@28216|Betaproteobacteria,1KIUW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
TLS2_k127_5418492_7	983917.RGE_09110	2.532e-52	189.0	COG3133@1|root,COG3133@2|Bacteria,1RJXC@1224|Proteobacteria,2VTKS@28216|Betaproteobacteria,1KKT0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	outer membrane lipoprotein	slyB	-	-	ko:K06077	-	-	-	-	ko00000	-	-	-	Rick_17kDa_Anti
TLS2_k127_5418492_10	1276756.AUEX01000030_gene198	6.434e-06	55.0	COG2227@1|root,COG2227@2|Bacteria,1QVH1@1224|Proteobacteria,2VRX7@28216|Betaproteobacteria,4AFK7@80864|Comamonadaceae	28216|Betaproteobacteria	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS2_k127_5418492_9	261292.Nit79A3_1539	3.484e-06	53.0	28XFS@1|root,2ZJDB@2|Bacteria,1P87W@1224|Proteobacteria,2W690@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2934
TLS2_k127_5418492_3	1163617.SCD_n01992	1.77e-169	546.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TLS2_k127_5434850_2	983917.RGE_40860	9.904e-115	372.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,2VJCQ@28216|Betaproteobacteria,1KJKF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
TLS2_k127_5434850_5	883126.HMPREF9710_04419	2.198e-70	244.0	COG1435@1|root,COG1435@2|Bacteria,1NJR4@1224|Proteobacteria,2W212@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
TLS2_k127_5434850_1	395495.Lcho_0585	2.309e-117	382.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,2VH2U@28216|Betaproteobacteria,1KJRE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
TLS2_k127_5434850_10	983917.RGE_40770	4.436e-31	131.0	2ERQY@1|root,33JA6@2|Bacteria,1QUWX@1224|Proteobacteria,2WGWJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_5434850_4	983917.RGE_40750	1.007e-79	273.0	COG0830@1|root,COG0830@2|Bacteria,1MW8Q@1224|Proteobacteria,2VRF6@28216|Betaproteobacteria,1KIX3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
TLS2_k127_5434850_3	420662.Mpe_A0665	6.061e-81	274.0	COG2371@1|root,COG2371@2|Bacteria,1MZQZ@1224|Proteobacteria,2VMRF@28216|Betaproteobacteria,1KJ8W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
TLS2_k127_5434850_11	887062.HGR_00946	7.321e-29	117.0	COG2336@1|root,COG2336@2|Bacteria,1N7UD@1224|Proteobacteria,2VW6P@28216|Betaproteobacteria,4AFGF@80864|Comamonadaceae	28216|Betaproteobacteria	T	Addiction module antidote	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
TLS2_k127_5434850_6	395495.Lcho_1579	9.984e-54	192.0	COG3654@1|root,COG3654@2|Bacteria,1N1FW@1224|Proteobacteria,2VTKH@28216|Betaproteobacteria,1KNPW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	TIGRFAM death-on-curing family protein	doc	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
TLS2_k127_5434850_0	983917.RGE_40090	0.0	1046.0	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,2VJYX@28216|Betaproteobacteria,1KK4I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
TLS2_k127_5434850_8	1123255.JHYS01000002_gene2432	1.649e-43	163.0	COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,2VSGJ@28216|Betaproteobacteria,4AEC1@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta
TLS2_k127_5434850_7	983917.RGE_40070	1.072e-47	172.0	COG0831@1|root,COG0831@2|Bacteria,1RGXE@1224|Proteobacteria,2VSES@28216|Betaproteobacteria,1KM0W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_gamma
TLS2_k127_5434850_9	983917.RGE_36530	9.578e-43	162.0	COG2703@1|root,COG2703@2|Bacteria,1MZJ3@1224|Proteobacteria,2VUV8@28216|Betaproteobacteria,1KMBT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
TLS2_k127_5454456_2	1286631.X805_16800	1.305e-63	222.0	COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,2VR3U@28216|Betaproteobacteria,1KKSR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Nudix hydrolase	ntpA	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
TLS2_k127_5454456_1	987059.RBXJA2T_07110	8.422e-136	444.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VJYW@28216|Betaproteobacteria,1KJGQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS2_k127_5454456_0	987059.RBXJA2T_07115	2.198e-181	581.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VI41@28216|Betaproteobacteria,1KJH6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsB	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
TLS2_k127_5460155_1	864051.BurJ1DRAFT_3298	3.737e-21	94.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2VJAC@28216|Betaproteobacteria,1KK3H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
TLS2_k127_5460155_0	864051.BurJ1DRAFT_3299	0.0	1193.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VI3F@28216|Betaproteobacteria,1KJIC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS2_k127_549330_1	983917.RGE_02940	1.141e-124	401.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2VIGU@28216|Betaproteobacteria,1KJU5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
TLS2_k127_549330_2	987059.RBXJA2T_03131	2.084e-58	205.0	COG1522@1|root,COG1522@2|Bacteria,1RE5H@1224|Proteobacteria,2VS27@28216|Betaproteobacteria,1KMQH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
TLS2_k127_549330_3	864051.BurJ1DRAFT_2520	8.05e-56	201.0	2F27V@1|root,33V61@2|Bacteria,1NVDD@1224|Proteobacteria,2W1VV@28216|Betaproteobacteria,1KNJN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_549330_0	983917.RGE_03050	1.108e-165	526.0	COG1748@1|root,COG1748@2|Bacteria,1MY1G@1224|Proteobacteria,2VMNG@28216|Betaproteobacteria,1KN8J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Saccharopine dehydrogenase C-terminal domain	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
TLS2_k127_5498809_0	522306.CAP2UW1_2481	6.436e-116	396.0	COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,2VKJT@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
TLS2_k127_5498809_1	395019.Bmul_3482	3.568e-26	123.0	2B3X8@1|root,31WM6@2|Bacteria,1RFRT@1224|Proteobacteria,2VRRY@28216|Betaproteobacteria,1K1U2@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3999)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999
TLS2_k127_5500432_0	391735.Veis_1308	0.0	1065.0	COG1002@1|root,COG2810@1|root,COG1002@2|Bacteria,COG2810@2|Bacteria,1NM9N@1224|Proteobacteria,2VPJC@28216|Betaproteobacteria,4AH8E@80864|Comamonadaceae	28216|Betaproteobacteria	L	Pfam:Methyltransf_26	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
TLS2_k127_5527090_0	983917.RGE_46830	5.497e-223	698.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria,1KJMZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K02031,ko:K02032,ko:K10823,ko:K13896,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00349,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.21,3.A.1.5.24,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
TLS2_k127_5527090_2	987059.RBXJA2T_07613	9.56e-164	539.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2VHWM@28216|Betaproteobacteria,1KKHI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
TLS2_k127_5527090_1	983917.RGE_46810	5.303e-164	522.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VN7U@28216|Betaproteobacteria,1KJSF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	gsiC_8	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
TLS2_k127_5527090_3	987059.RBXJA2T_07623	1.592e-22	100.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,1KJPX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
TLS2_k127_5529946_1	987059.RBXJA2T_06440	9.548e-152	487.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2VI25@28216|Betaproteobacteria,1KJYV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
TLS2_k127_5529946_0	983917.RGE_41130	7.575e-169	535.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2VI2A@28216|Betaproteobacteria,1KJ68@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
TLS2_k127_5529946_2	864051.BurJ1DRAFT_4109	5.28e-136	451.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,1KJRI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645,ko:K15355	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
TLS2_k127_5550038_1	983917.RGE_46210	1.329e-133	430.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2VI3S@28216|Betaproteobacteria,1KJAP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
TLS2_k127_5550038_0	864051.BurJ1DRAFT_3445	6.447e-176	556.0	COG1118@1|root,COG1118@2|Bacteria,1QTTT@1224|Proteobacteria,2VH92@28216|Betaproteobacteria,1KKEI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_3
TLS2_k127_5550038_2	861299.J421_5906	2.092e-18	98.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
TLS2_k127_5550038_3	1379698.RBG1_1C00001G0607	0.0003759	52.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
TLS2_k127_5555575_0	983917.RGE_37700	1.273e-249	785.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria	28216|Betaproteobacteria	G	carbohydrate binding	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
TLS2_k127_5566939_4	987059.RBXJA2T_11036	8.487e-35	134.0	COG0454@1|root,COG0456@2|Bacteria,1PNX8@1224|Proteobacteria,2VR63@28216|Betaproteobacteria,1KKZ1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS2_k127_5566939_1	987059.RBXJA2T_11031	2.804e-131	424.0	COG2017@1|root,COG2017@2|Bacteria,1RGXX@1224|Proteobacteria,2VQB2@28216|Betaproteobacteria,1KN19@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
TLS2_k127_5566939_2	395495.Lcho_3534	2.969e-130	423.0	COG3386@1|root,COG3386@2|Bacteria,1MWTR@1224|Proteobacteria,2VMAD@28216|Betaproteobacteria,1KJBD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	SMP-30 Gluconolaconase	-	-	3.1.1.15	ko:K13874,ko:K14274	ko00040,ko00053,ko01100,map00040,map00053,map01100	-	R02427,R02526	RC00537,RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
TLS2_k127_5566939_0	983917.RGE_02320	1.865e-251	801.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2VN8I@28216|Betaproteobacteria,1KJK1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
TLS2_k127_5566939_3	983917.RGE_02310	1.067e-116	380.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,1KJNA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	-	-	1.8.1.8	ko:K04084,ko:K08344	-	-	-	-	ko00000,ko01000,ko02000,ko03110	5.A.1.1,5.A.1.5	-	-	DsbC,DsbD,Thioredoxin_7
TLS2_k127_5574979_1	987059.RBXJA2T_16507	1.022e-253	792.0	COG0128@1|root,COG0283@1|root,COG0128@2|Bacteria,COG0283@2|Bacteria,1MWMK@1224|Proteobacteria,2VGZF@28216|Betaproteobacteria,1KK6W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
TLS2_k127_5574979_0	987059.RBXJA2T_16502	0.0	1047.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,1KIV0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
TLS2_k127_5574979_2	983917.RGE_13860	2.117e-49	179.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2VSPN@28216|Betaproteobacteria,1KM2X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
TLS2_k127_5574979_3	983917.RGE_13850	2.23e-33	131.0	COG5416@1|root,COG5416@2|Bacteria,1N4UI@1224|Proteobacteria,2VU63@28216|Betaproteobacteria,1KMI6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Pfam:DUF1049	-	-	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
TLS2_k127_5595755_2	864051.BurJ1DRAFT_3603	2.873e-105	347.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,1KJ4S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
TLS2_k127_5595755_1	1286631.X805_26090	5.475e-188	593.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2VHD0@28216|Betaproteobacteria,1KJ48@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
TLS2_k127_5595755_3	987059.RBXJA2T_12717	7.367e-97	320.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2VIQP@28216|Betaproteobacteria,1KK3G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
TLS2_k127_5595755_4	987059.RBXJA2T_12722	4.11e-79	272.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2VJ4G@28216|Betaproteobacteria,1KKDT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
TLS2_k127_5595755_5	987059.RBXJA2T_12727	5.189e-47	173.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2VSDV@28216|Betaproteobacteria,1KM2T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
TLS2_k127_5595755_0	987059.RBXJA2T_12732	5.255e-275	853.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,1KIU8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CP	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
TLS2_k127_56030_1	861299.J421_5687	2.059e-33	141.0	COG2207@1|root,COG2207@2|Bacteria,1ZV4P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS2_k127_56030_0	509190.Cseg_0727	3.34e-69	254.0	COG1680@1|root,COG1680@2|Bacteria,1RHDA@1224|Proteobacteria,2VEYX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS2_k127_56030_2	983917.RGE_06700	7.278e-08	55.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	menC	GO:0008150,GO:0040007	4.2.1.113,5.1.1.20,5.1.1.3	ko:K01776,ko:K02549,ko:K19802	ko00130,ko00471,ko01100,ko01110,map00130,map00471,map01100,map01110	M00116	R00260,R04031,R10938	RC00302,RC01053,RC03309	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	iNJ661.Rv0553,iSB619.SA_RS09080	MR_MLE_C
TLS2_k127_560639_1	1385513.N780_17735	1.224e-11	76.0	COG4421@1|root,COG4421@2|Bacteria,1V4A4@1239|Firmicutes,4HI6J@91061|Bacilli	91061|Bacilli	G	Protein of unknown function (DUF563)	-	-	-	-	-	-	-	-	-	-	-	-	DUF563
TLS2_k127_560639_0	1127673.GLIP_0719	1.771e-145	486.0	2FEPR@1|root,346NZ@2|Bacteria,1PHDB@1224|Proteobacteria,1SR78@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Exostosin family	-	-	-	-	-	-	-	-	-	-	-	-	Exostosin
TLS2_k127_5611726_1	395495.Lcho_2215	4.832e-120	391.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,1KNEZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
TLS2_k127_5611726_0	1100721.ALKO01000003_gene2113	2.224e-158	506.0	COG3181@1|root,COG3181@2|Bacteria,1N7C4@1224|Proteobacteria,2VHNI@28216|Betaproteobacteria,4A9W4@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
TLS2_k127_5611726_2	925409.KI911562_gene971	8.928e-61	218.0	COG4122@1|root,COG4122@2|Bacteria,4NGQ1@976|Bacteroidetes,1IT5B@117747|Sphingobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
TLS2_k127_5611726_3	1100721.ALKO01000021_gene566	2.067e-08	60.0	COG1073@1|root,COG1073@2|Bacteria,1QTY2@1224|Proteobacteria,2VK86@28216|Betaproteobacteria,4AB75@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Tannase and feruloyl esterase	-	-	3.1.1.102	ko:K21105	-	-	R11541	RC00020,RC00041	ko00000,ko01000	-	-	-	Tannase
TLS2_k127_5717086_0	983917.RGE_01070	0.0	1059.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,2VINZ@28216|Betaproteobacteria,1KJD0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
TLS2_k127_5717086_1	987059.RBXJA2T_05273	4.436e-114	372.0	COG1409@1|root,COG1409@2|Bacteria,1R4AZ@1224|Proteobacteria,2VIHN@28216|Betaproteobacteria,1KJHN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
TLS2_k127_5717086_2	987059.RBXJA2T_05278	5.291e-55	195.0	COG0589@1|root,COG0589@2|Bacteria,1N8EJ@1224|Proteobacteria,2VUAF@28216|Betaproteobacteria,1KM2Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS2_k127_5717495_1	983917.RGE_24520	2.944e-307	944.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2VHFD@28216|Betaproteobacteria,1KJAM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
TLS2_k127_5717495_3	983917.RGE_24530	6.793e-101	331.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2VQ19@28216|Betaproteobacteria,1KJ15@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
TLS2_k127_5717495_7	1538295.JY96_03205	8.318e-32	126.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2VVS9@28216|Betaproteobacteria,1KM9M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
TLS2_k127_5717495_4	395495.Lcho_1748	2.26e-61	212.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,1KKVN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
TLS2_k127_5717495_2	983917.RGE_24560	7.882e-194	609.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,1KJGE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
TLS2_k127_5717495_0	1286631.X805_27540	0.0	1159.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,1KJ89@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
TLS2_k127_5717495_5	983917.RGE_24580	1.38e-56	205.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2VT12@28216|Betaproteobacteria,1KM26@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
TLS2_k127_5717495_6	983917.RGE_24590	7.582e-53	189.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2VSDF@28216|Betaproteobacteria,1KM47@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	regulatory protein, MerR	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
TLS2_k127_5717495_8	864051.BurJ1DRAFT_0172	6.262e-12	66.0	2CIC8@1|root,33JK4@2|Bacteria,1NH5Z@1224|Proteobacteria,2VYDU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_5733118_4	391625.PPSIR1_24259	4.735e-57	210.0	COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,43DUB@68525|delta/epsilon subdivisions,2WYWH@28221|Deltaproteobacteria,2Z0T1@29|Myxococcales	28221|Deltaproteobacteria	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
TLS2_k127_5733118_5	1443665.JACA01000003_gene855	2.149e-35	138.0	COG3350@1|root,COG3350@2|Bacteria	2|Bacteria	T	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	YHS
TLS2_k127_5733118_1	1454004.AW11_01340	2.892e-157	499.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VK4X@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS2_k127_5733118_3	1454004.AW11_01339	5.13e-66	234.0	COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria	1224|Proteobacteria	S	Doxx family	mhqP	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
TLS2_k127_5733118_2	1454004.AW11_01338	1.935e-129	418.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,2VIC3@28216|Betaproteobacteria,1KQV4@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	ygiD	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
TLS2_k127_5733118_0	1198452.Jab_1c14230	7.442e-276	863.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VI18@28216|Betaproteobacteria,473H2@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS2_k127_573915_1	420662.Mpe_A3544	1.468e-80	276.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,2VHZ1@28216|Betaproteobacteria,1KJ7K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Alpha beta hydrolase	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
TLS2_k127_573915_2	420662.Mpe_A3545	1.5e-42	160.0	COG4319@1|root,COG4319@2|Bacteria,1MZK9@1224|Proteobacteria,2VU96@28216|Betaproteobacteria,1KM1J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
TLS2_k127_573915_0	983917.RGE_01580	1.865e-142	458.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,2VIXE@28216|Betaproteobacteria,1KJBU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,ACT_6,Formyl_trans_N
TLS2_k127_5741893_2	864051.BurJ1DRAFT_4792	8.86e-06	48.0	29SCQ@1|root,32R95@2|Bacteria,1RIT7@1224|Proteobacteria,2VSUG@28216|Betaproteobacteria,1KM4E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_5741893_1	1502852.FG94_04407	4.171e-40	160.0	2AWDG@1|root,31N9E@2|Bacteria,1PWN3@1224|Proteobacteria,2WC68@28216|Betaproteobacteria,4771X@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_5741893_0	1121015.N789_02275	1.892e-309	960.0	COG0308@1|root,COG0308@2|Bacteria,1MUV3@1224|Proteobacteria,1RS0E@1236|Gammaproteobacteria,1X344@135614|Xanthomonadales	135614|Xanthomonadales	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
TLS2_k127_5750409_0	987059.RBXJA2T_18443	1.764e-156	509.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria,1KJYZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
TLS2_k127_5750409_2	358220.C380_04795	2.501e-96	327.0	COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,2VIZ1@28216|Betaproteobacteria,4AB04@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS2_k127_5750409_1	987059.RBXJA2T_15138	1.383e-121	398.0	2DBFU@1|root,2Z90B@2|Bacteria,1PI0M@1224|Proteobacteria,2WGPR@28216|Betaproteobacteria,1KPCW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
TLS2_k127_5750409_3	864051.BurJ1DRAFT_3764	8.049e-12	69.0	COG1525@1|root,COG1525@2|Bacteria,1PQ4N@1224|Proteobacteria,2W9KT@28216|Betaproteobacteria,1KMJ0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Staphylococcal nuclease homologue	-	-	-	-	-	-	-	-	-	-	-	-	SNase
TLS2_k127_5782124_0	1198452.Jab_2c26080	9.471e-93	323.0	COG2199@1|root,COG2199@2|Bacteria,1RKMU@1224|Proteobacteria,2WBGU@28216|Betaproteobacteria,475SJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
TLS2_k127_5782124_2	883126.HMPREF9710_01708	1.346e-64	253.0	COG2199@1|root,COG2199@2|Bacteria,1RKMU@1224|Proteobacteria,2WBGU@28216|Betaproteobacteria,475SJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
TLS2_k127_5782124_1	864051.BurJ1DRAFT_1515	5.162e-65	233.0	COG1629@1|root,COG4771@2|Bacteria,1QWIP@1224|Proteobacteria,2VKD5@28216|Betaproteobacteria,1KKH8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
TLS2_k127_5786778_1	864051.BurJ1DRAFT_2912	1.027e-165	531.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2VIYE@28216|Betaproteobacteria,1KJAR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Elongator protein 3, MiaB family, Radical SAM	splB	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS2_k127_5786778_0	983917.RGE_27160	5.084e-249	779.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,1KJ8B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
TLS2_k127_5786778_2	987059.RBXJA2T_18106	2.941e-67	231.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2VR40@28216|Betaproteobacteria,1KKZX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
TLS2_k127_5786778_3	864051.BurJ1DRAFT_2915	2.919e-50	179.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2VTWT@28216|Betaproteobacteria,1KM20@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
TLS2_k127_5786778_4	864051.BurJ1DRAFT_2916	6.098e-30	122.0	COG2965@1|root,COG2965@2|Bacteria,1N98W@1224|Proteobacteria,2VVZ4@28216|Betaproteobacteria,1KMH3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Binds single-stranded DNA at the primosome assembly site (PAS)	priB	-	-	ko:K02686	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SSB
TLS2_k127_5810498_0	864051.BurJ1DRAFT_4843	1.611e-104	350.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,2VI5K@28216|Betaproteobacteria,1KJIB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Eukaryotic-type carbonic anhydrase	ecaA	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
TLS2_k127_5810498_1	1235457.C404_03355	2.816e-39	157.0	COG2199@1|root,COG2202@1|root,COG3290@1|root,COG4191@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,COG3290@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2WHCU@28216|Betaproteobacteria,1KIMC@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4,dCache_1
TLS2_k127_5813035_5	864051.BurJ1DRAFT_3485	7.607e-33	135.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2VH4V@28216|Betaproteobacteria,1KN30@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
TLS2_k127_5813035_2	864051.BurJ1DRAFT_3486	2.897e-137	443.0	COG0438@1|root,COG0438@2|Bacteria,1RB3J@1224|Proteobacteria,2VJNY@28216|Betaproteobacteria,1KN1C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
TLS2_k127_5813035_1	864051.BurJ1DRAFT_3487	6.341e-189	599.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,2VJSD@28216|Betaproteobacteria,1KK9A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
TLS2_k127_5813035_3	365044.Pnap_0052	7.302e-38	145.0	2EBXW@1|root,335X8@2|Bacteria,1NBMB@1224|Proteobacteria,2VWB7@28216|Betaproteobacteria,4AFSD@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_5813035_4	365044.Pnap_0051	8.712e-37	140.0	COG2104@1|root,COG2104@2|Bacteria,1N9VX@1224|Proteobacteria,2VVYE@28216|Betaproteobacteria,4AFRB@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM thiamineS protein	-	-	-	-	-	-	-	-	-	-	-	-	ThiS,Ub-Mut7C
TLS2_k127_5813035_0	395495.Lcho_1818	3.291e-192	606.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2WH5F@28216|Betaproteobacteria,1KPCV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
TLS2_k127_5832878_4	1100721.ALKO01000027_gene397	2.127e-13	70.0	2DMP1@1|root,32SS8@2|Bacteria,1N0XZ@1224|Proteobacteria,2VRVN@28216|Betaproteobacteria,4AE8I@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0311 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
TLS2_k127_5832878_0	1100721.ALKO01000019_gene1358	1.665e-136	441.0	COG3181@1|root,COG3181@2|Bacteria,1N00G@1224|Proteobacteria,2VN46@28216|Betaproteobacteria,4ADS3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
TLS2_k127_5832878_3	365046.Rta_30930	1.161e-38	164.0	COG1846@1|root,COG1846@2|Bacteria,1N5CQ@1224|Proteobacteria,2VT0D@28216|Betaproteobacteria,4AF4J@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS2_k127_5832878_1	391735.Veis_4197	5.024e-112	376.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2VIRU@28216|Betaproteobacteria,4AC6I@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Ornithine cyclodeaminase mu-crystallin	-	-	1.5.1.1,4.3.1.12	ko:K01750,ko:K19743	ko00310,ko00330,ko00960,ko01100,ko01110,ko01130,ko01230,map00310,map00330,map00960,map01100,map01110,map01130,map01230	-	R00671,R01246,R01249,R02201,R02203	RC00135,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
TLS2_k127_5832878_2	365044.Pnap_2835	8.266e-60	207.0	COG1136@1|root,COG1136@2|Bacteria,1MXVW@1224|Proteobacteria,2VI95@28216|Betaproteobacteria,4ABSQ@80864|Comamonadaceae	28216|Betaproteobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS2_k127_5837962_2	983917.RGE_45230	2.622e-91	314.0	COG4566@1|root,COG4566@2|Bacteria,1RAEP@1224|Proteobacteria,2WEEG@28216|Betaproteobacteria,1KKKF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	dctR	-	-	ko:K11712	ko02020,map02020	-	-	-	ko00000,ko00001,ko02022	-	-	-	GerE,Response_reg
TLS2_k127_5837962_1	987059.RBXJA2T_02877	3.142e-252	797.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,1KKA1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	dctS	-	2.7.13.3	ko:K11711	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
TLS2_k127_5837962_0	395495.Lcho_3916	0.0	1304.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,1KIY8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_DH,Malic_M,PTA_PTB,malic
TLS2_k127_5837962_4	1219031.BBJR01000045_gene1822	4.755e-41	156.0	COG4290@1|root,COG4290@2|Bacteria,1MZEZ@1224|Proteobacteria,2VTZ7@28216|Betaproteobacteria,4AEXX@80864|Comamonadaceae	28216|Betaproteobacteria	F	guanine-specific ribonuclease N1 and T1	rnaSA	-	3.1.27.3	ko:K01167	-	-	-	-	ko00000,ko01000,ko03016,ko03019	-	-	-	Ribonuclease
TLS2_k127_5837962_3	983917.RGE_45270	2.322e-70	242.0	COG2732@1|root,COG2732@2|Bacteria,1RD25@1224|Proteobacteria,2VR9C@28216|Betaproteobacteria,1KKU0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Barstar (barnase inhibitor)	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
TLS2_k127_5847892_2	187272.Mlg_1798	2.847e-77	272.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,1RYPY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Transposase, IS801 IS1294	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
TLS2_k127_5847892_0	543728.Vapar_5836	3.374e-169	536.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2VHJU@28216|Betaproteobacteria,4AB94@80864|Comamonadaceae	28216|Betaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
TLS2_k127_5847892_1	864051.BurJ1DRAFT_1963	1.692e-138	449.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria,1KK1H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
TLS2_k127_5915241_4	1121935.AQXX01000123_gene203	1.749e-05	48.0	COG1192@1|root,COG1192@2|Bacteria,1MVEZ@1224|Proteobacteria,1RPWA@1236|Gammaproteobacteria,1XI4F@135619|Oceanospirillales	135619|Oceanospirillales	D	COG1192 ATPases involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
TLS2_k127_5915241_2	395495.Lcho_4211	7.95e-67	233.0	297U7@1|root,2ZV0V@2|Bacteria,1RE3I@1224|Proteobacteria,2VRCN@28216|Betaproteobacteria,1KNI1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_5915241_3	381666.H16_B0858	4.028e-36	151.0	COG0640@1|root,COG0640@2|Bacteria,1N10H@1224|Proteobacteria,2VUMP@28216|Betaproteobacteria,1K8ZS@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
TLS2_k127_5915241_1	977880.RALTA_B0715	1.256e-81	275.0	COG3832@1|root,COG3832@2|Bacteria,1RD0P@1224|Proteobacteria,2VS78@28216|Betaproteobacteria,1K76G@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS2_k127_5915241_0	395495.Lcho_2996	6.075e-308	951.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,2VKPN@28216|Betaproteobacteria,1KJM9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
TLS2_k127_592767_1	987059.RBXJA2T_10736	1.329e-223	702.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2VHY5@28216|Betaproteobacteria,1KJCB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
TLS2_k127_592767_3	987059.RBXJA2T_10741	6.118e-98	335.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria,1KKI5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	HAD-superfamily hydrolase, subfamily IB (PSPase-like)	-	-	-	-	-	-	-	-	-	-	-	-	HAD
TLS2_k127_592767_4	864051.BurJ1DRAFT_3104	4.711e-89	302.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,2VSFD@28216|Betaproteobacteria,1KKNJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Belongs to the DnaA family	hda	-	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
TLS2_k127_592767_2	987059.RBXJA2T_10751	3.792e-104	345.0	COG2912@1|root,COG2912@2|Bacteria,1MVJQ@1224|Proteobacteria,2VMIR@28216|Betaproteobacteria,1KKIU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
TLS2_k127_592767_0	987059.RBXJA2T_10756	7.553e-234	736.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,1KK6B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
TLS2_k127_592767_6	983917.RGE_13350	3.326e-37	156.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2VTYY@28216|Betaproteobacteria,1KMD3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
TLS2_k127_592767_5	864051.BurJ1DRAFT_3109	2.797e-41	156.0	COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria,2VU1F@28216|Betaproteobacteria,1KM0F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Protein of unknown function (DUF3579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3579
TLS2_k127_5934258_3	987059.RBXJA2T_05463	1.183e-64	230.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VINY@28216|Betaproteobacteria,1KJ0I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
TLS2_k127_5934258_4	1265502.KB905934_gene3208	1.629e-40	154.0	COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2VVZF@28216|Betaproteobacteria,4AEJH@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM Transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
TLS2_k127_5934258_0	987059.RBXJA2T_05468	6.472e-200	631.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2VI1Y@28216|Betaproteobacteria,1KJSJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Peptidase M48	htpX_2	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
TLS2_k127_5934258_2	983917.RGE_13550	1.136e-100	332.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,2VIA2@28216|Betaproteobacteria,1KJIX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	A	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
TLS2_k127_5934258_1	983917.RGE_33860	3.441e-183	580.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,1KJGR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
TLS2_k127_5963045_2	983917.RGE_44810	1.065e-142	481.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VKV7@28216|Betaproteobacteria,1KJ0Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CH	UbiH UbiF VisC COQ6 family	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
TLS2_k127_5963045_1	420662.Mpe_A0246	7.44e-175	572.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,2VJ2P@28216|Betaproteobacteria,1KJEH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17,SHOCT
TLS2_k127_5963045_0	1286631.X805_17990	2.233e-175	561.0	COG1379@1|root,COG1379@2|Bacteria,1MVED@1224|Proteobacteria,2VJM0@28216|Betaproteobacteria,1KJW4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
TLS2_k127_5972122_3	983917.RGE_38960	6.859e-132	427.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2VJ4F@28216|Betaproteobacteria,1KJH9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
TLS2_k127_5972122_4	983917.RGE_38950	1.068e-108	360.0	COG0741@1|root,COG0741@2|Bacteria,1RAP3@1224|Proteobacteria,2VQXG@28216|Betaproteobacteria,1KJ11@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	lytic transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	SLT
TLS2_k127_5972122_1	983917.RGE_38940	9.745e-288	892.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VH09@28216|Betaproteobacteria,1KKD7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the UbiD family	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
TLS2_k127_5972122_2	596154.Alide2_0526	2.328e-225	709.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2VI6F@28216|Betaproteobacteria,4A9MZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the GMC oxidoreductase family	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
TLS2_k127_5972122_0	987059.RBXJA2T_10951	1.503e-300	937.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VIAP@28216|Betaproteobacteria,1KJ8T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS2_k127_5985784_1	864051.BurJ1DRAFT_2271	5.854e-147	467.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,1KJ9F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	fadB	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
TLS2_k127_5985784_0	1265502.KB905940_gene2998	3.734e-211	660.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,4AA4T@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
TLS2_k127_5985784_5	1123504.JQKD01000002_gene3842	0.0007322	46.0	2EVGE@1|root,33NWT@2|Bacteria,1NGBG@1224|Proteobacteria,2VZ1Y@28216|Betaproteobacteria,4AFTJ@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_5985784_3	987059.RBXJA2T_08855	4.87e-65	226.0	COG2153@1|root,COG2153@2|Bacteria,1MZHA@1224|Proteobacteria,2VTYH@28216|Betaproteobacteria,1KMFG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Acetyltransferase (GNAT) domain	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
TLS2_k127_5985784_2	1265502.KB905940_gene2991	1.506e-69	249.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VHMA@28216|Betaproteobacteria,4A9UE@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
TLS2_k127_6037576_2	1328313.DS2_07048	1.57e-06	56.0	COG2850@1|root,COG2850@2|Bacteria,1MUAC@1224|Proteobacteria,1RQQP@1236|Gammaproteobacteria,465RI@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
TLS2_k127_6037576_1	760117.JN27_01145	3.815e-91	306.0	COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,2VVF7@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SapC	-	-	-	-	-	-	-	-	-	-	-	-	SapC
TLS2_k127_6037576_0	1198452.Jab_1c09490	2.229e-223	702.0	COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,2VSIK@28216|Betaproteobacteria,475HS@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
TLS2_k127_6061997_1	395495.Lcho_1327	1.184e-41	158.0	COG1191@1|root,COG1191@2|Bacteria,1NU0U@1224|Proteobacteria,2VZXG@28216|Betaproteobacteria,1KNDG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r4
TLS2_k127_6061997_0	420662.Mpe_A2126	1.138e-285	886.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,1KIY6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
TLS2_k127_6078441_1	983917.RGE_38090	1.332e-174	567.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,2VJB1@28216|Betaproteobacteria,1KMXV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
TLS2_k127_6078441_0	987059.RBXJA2T_01470	1.111e-318	983.0	COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,2VK3E@28216|Betaproteobacteria,1KMZR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
TLS2_k127_6086153_4	420662.Mpe_A2192	3.146e-68	245.0	COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,2VNS7@28216|Betaproteobacteria,1KKAD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	import inner membrane translocase subunit Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
TLS2_k127_6086153_3	983917.RGE_23880	1.219e-74	261.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,2VSH4@28216|Betaproteobacteria,1KM65@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
TLS2_k127_6086153_0	987059.RBXJA2T_08325	1.168e-226	707.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2VHDV@28216|Betaproteobacteria,1KIUX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS2_k127_6086153_2	983917.RGE_23930	2.103e-77	263.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2VR6F@28216|Betaproteobacteria,1KKV2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
TLS2_k127_6086153_6	864051.BurJ1DRAFT_1973	6.507e-14	81.0	2FKW3@1|root,34CGE@2|Bacteria,1P9MH@1224|Proteobacteria,2W6E9@28216|Betaproteobacteria,1KP7E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6086153_5	864051.BurJ1DRAFT_1974	9.464e-26	112.0	29042@1|root,2ZMU1@2|Bacteria,1PABH@1224|Proteobacteria,2W5HD@28216|Betaproteobacteria,1KP4K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6086153_1	420662.Mpe_A1822	4.507e-104	345.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2VIWI@28216|Betaproteobacteria,1KM79@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
TLS2_k127_6093274_0	562970.Btus_1727	3.849e-65	230.0	COG1960@1|root,COG1960@2|Bacteria,1TSN3@1239|Firmicutes,4HB0T@91061|Bacilli,278X4@186823|Alicyclobacillaceae	91061|Bacilli	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249,ko:K11731	ko00071,ko00280,ko00281,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00281,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754,R08089	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246,RC01893	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS2_k127_6093274_1	767817.Desgi_1135	7.278e-44	165.0	COG2030@1|root,COG2030@2|Bacteria,1VE44@1239|Firmicutes,24SWZ@186801|Clostridia	186801|Clostridia	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
TLS2_k127_6093274_2	767817.Desgi_1150	1.195e-38	157.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,25073@186801|Clostridia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS2_k127_609700_3	987059.RBXJA2T_17981	6.181e-141	454.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,1KJ8G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
TLS2_k127_609700_0	987059.RBXJA2T_17986	1.871e-175	566.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2VJZD@28216|Betaproteobacteria,1KJCE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	-	-	-	-	-	-	-	-	-	-	Carb_kinase,YjeF_N
TLS2_k127_609700_2	987059.RBXJA2T_17991	1.754e-144	470.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2VH1D@28216|Betaproteobacteria,1KIW9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	FAD dependent oxidoreductase	-	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
TLS2_k127_609700_4	983917.RGE_27390	1.273e-139	453.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2VI8V@28216|Betaproteobacteria,1KJMP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
TLS2_k127_609700_1	987059.RBXJA2T_18006	4.74e-151	483.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria,1KJ30@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
TLS2_k127_609700_5	864051.BurJ1DRAFT_2933	4.986e-135	435.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2VH8A@28216|Betaproteobacteria,1KJU7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
TLS2_k127_609700_7	987059.RBXJA2T_18016	7.662e-92	304.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,1KJGT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
TLS2_k127_609700_6	987059.RBXJA2T_18021	1.202e-127	411.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,1KIUJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
TLS2_k127_6097506_0	983917.RGE_33830	9.291e-209	669.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria,1KJF7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
TLS2_k127_6097506_1	864051.BurJ1DRAFT_4817	4.819e-119	387.0	COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,2VN69@28216|Betaproteobacteria,1KK9F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
TLS2_k127_6097506_2	987059.RBXJA2T_00560	2.492e-70	240.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VSW6@28216|Betaproteobacteria,1KKTH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS2_k127_6097506_3	987059.RBXJA2T_00565	9.645e-58	203.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria,1KJDB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
TLS2_k127_6097791_0	177439.DP2106	1.708e-171	558.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,42SXK@68525|delta/epsilon subdivisions,2WQ2W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16
TLS2_k127_6097791_1	1123255.JHYS01000005_gene791	6.534e-55	209.0	COG0747@1|root,COG0823@1|root,COG1404@1|root,COG2982@1|root,COG0747@2|Bacteria,COG0823@2|Bacteria,COG1404@2|Bacteria,COG2982@2|Bacteria,1QU1I@1224|Proteobacteria	1224|Proteobacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Peptidase_S8
TLS2_k127_6107296_3	983917.RGE_27020	6.138e-11	68.0	COG2916@1|root,COG2916@2|Bacteria,1N7YA@1224|Proteobacteria,2VW5J@28216|Betaproteobacteria,1KM8S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Histone family protein nucleoid-structuring protein H-NS	-	-	-	ko:K03746	-	-	-	-	ko00000,ko03036,ko03400	-	-	-	Histone_HNS
TLS2_k127_6107296_1	987059.RBXJA2T_01425	2.902e-45	164.0	COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,2VTYU@28216|Betaproteobacteria,1KM13@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	yggX	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
TLS2_k127_6107296_0	983917.RGE_26990	2.801e-257	797.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,2VGZC@28216|Betaproteobacteria,1KJ7S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
TLS2_k127_6107296_2	395495.Lcho_2227	2.514e-41	158.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,2VV6T@28216|Betaproteobacteria,1KM93@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS2_k127_6124873_1	420662.Mpe_A1076	7.778e-212	678.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,2VKC9@28216|Betaproteobacteria,1KJ2Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	TonB dependent receptor	yncD	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
TLS2_k127_6124873_2	395495.Lcho_3377	1.501e-30	123.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,2VWKS@28216|Betaproteobacteria,1KMK0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	PFAM Cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
TLS2_k127_6124873_0	395495.Lcho_3378	8.247e-244	754.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VIRC@28216|Betaproteobacteria,1KJZ9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,SGL
TLS2_k127_6129727_2	983917.RGE_12150	3.184e-124	403.0	COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,2VINN@28216|Betaproteobacteria,1KJ9N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Exonuclease C-terminal	sbcB	-	3.1.11.1	ko:K01141	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_X-T_C,RNase_T
TLS2_k127_6129727_0	243365.CV_0292	5.244e-253	796.0	COG0737@1|root,COG0737@2|Bacteria,1MU11@1224|Proteobacteria,2VJC2@28216|Betaproteobacteria,2KQCH@206351|Neisseriales	206351|Neisseriales	F	5'-nucleotidase, C-terminal domain	cpdB	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
TLS2_k127_6129727_1	395495.Lcho_2709	7.059e-149	479.0	COG2301@1|root,COG2301@2|Bacteria,1Q91U@1224|Proteobacteria,2VJJY@28216|Betaproteobacteria,1KJMT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
TLS2_k127_6129727_3	596153.Alide_1963	1.557e-65	225.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2VHC8@28216|Betaproteobacteria,4AA24@80864|Comamonadaceae	28216|Betaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
TLS2_k127_6132068_2	987059.RBXJA2T_17192	1.572e-104	346.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,2VK7S@28216|Betaproteobacteria,1KIWR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Spermidine synthase	speE1	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
TLS2_k127_6132068_0	987059.RBXJA2T_17197	4.106e-311	967.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,1KJ32@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	type II secretion system protein E	gspE1	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
TLS2_k127_6132068_1	983917.RGE_21720	3.432e-215	686.0	COG0477@1|root,COG1359@1|root,COG0477@2|Bacteria,COG1359@2|Bacteria,1MXZ3@1224|Proteobacteria,2VH3E@28216|Betaproteobacteria,1KIUH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
TLS2_k127_6142487_0	864051.BurJ1DRAFT_2004	2.074e-106	351.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,2VJPP@28216|Betaproteobacteria,1KJ41@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	ThiF family	moeB	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
TLS2_k127_6142487_2	864051.BurJ1DRAFT_3414	9.362e-58	206.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2W46V@28216|Betaproteobacteria	28216|Betaproteobacteria	S	YHS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
TLS2_k127_6142487_1	395494.Galf_1895	3.205e-81	279.0	COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,2VKKD@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
TLS2_k127_6146020_1	338969.Rfer_3390	1.878e-101	335.0	COG2207@1|root,COG2207@2|Bacteria,1MY46@1224|Proteobacteria,2VJIK@28216|Betaproteobacteria,4AAS6@80864|Comamonadaceae	28216|Betaproteobacteria	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18,HTH_AraC
TLS2_k127_6146020_3	287986.DV20_28470	2.013e-43	165.0	COG2128@1|root,COG2128@2|Bacteria,2IFPC@201174|Actinobacteria,4EEQZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
TLS2_k127_6146020_0	358220.C380_11175	8.326e-139	448.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2VHV1@28216|Betaproteobacteria,4ABAB@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM aldo keto reductase	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
TLS2_k127_6146020_2	987059.RBXJA2T_10064	1.201e-62	217.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2VIU0@28216|Betaproteobacteria,1KJ5C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Riboflavin synthase	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
TLS2_k127_615226_1	1538295.JY96_14965	2.479e-86	291.0	COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,2W1JF@28216|Betaproteobacteria,1KK07@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
TLS2_k127_615226_0	1123368.AUIS01000004_gene115	3.52e-127	442.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4,Response_reg
TLS2_k127_615226_2	864051.BurJ1DRAFT_1497	1.055e-35	140.0	COG0745@1|root,COG0745@2|Bacteria,1N8Z8@1224|Proteobacteria,2VW99@28216|Betaproteobacteria,1KNT2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS2_k127_6167743_0	926569.ANT_10260	2.737e-87	294.0	COG0024@1|root,COG0024@2|Bacteria,2G6AV@200795|Chloroflexi	200795|Chloroflexi	J	TIGRFAM methionine aminopeptidase, type I	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
TLS2_k127_6167743_2	70448.Q0P3P7	7.846e-11	64.0	2CZUB@1|root,2SBPU@2759|Eukaryota,3844C@33090|Viridiplantae,34NNP@3041|Chlorophyta	3041|Chlorophyta	J	structural constituent of ribosome	rpl36	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Ribosomal_L36
TLS2_k127_6167743_1	926569.ANT_10280	6.001e-58	203.0	COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi	200795|Chloroflexi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
TLS2_k127_6183824_1	358220.C380_09415	1.866e-107	351.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VH78@28216|Betaproteobacteria,4AAFY@80864|Comamonadaceae	28216|Betaproteobacteria	H	MoeA domain protein domain I and II	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
TLS2_k127_6183824_2	358220.C380_09425	1.41e-100	331.0	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,2VQR2@28216|Betaproteobacteria,4ABJP@80864|Comamonadaceae	28216|Betaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
TLS2_k127_6183824_0	614083.AWQR01000005_gene985	2.751e-130	419.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,4AB8M@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
TLS2_k127_6195853_0	1122612.AUBA01000018_gene2629	8.892e-127	418.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2TTTU@28211|Alphaproteobacteria,2K2VI@204457|Sphingomonadales	204457|Sphingomonadales	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS2_k127_6195853_3	439496.RBY4I_1247	5.787e-36	144.0	COG3161@1|root,COG3161@2|Bacteria,1N1ZT@1224|Proteobacteria	1224|Proteobacteria	H	chorismate lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6195853_2	525904.Tter_1546	1.052e-82	296.0	COG0147@1|root,COG0147@2|Bacteria,2NP4C@2323|unclassified Bacteria	2|Bacteria	EH	chorismate binding enzyme	pabB	-	2.6.1.85	ko:K01665,ko:K13950	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
TLS2_k127_6195853_5	614083.AWQR01000030_gene2709	2.69e-29	126.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS2_k127_6195853_4	983917.RGE_31720	9.015e-34	131.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,1KMN9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	'Cold-shock' DNA-binding domain	cspD	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
TLS2_k127_6195853_1	420662.Mpe_A2461	4.674e-108	351.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria,1KK7T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
TLS2_k127_6203541_2	987059.RBXJA2T_09782	8.997e-65	230.0	COG0515@1|root,COG1639@1|root,COG0515@2|Bacteria,COG1639@2|Bacteria,1NJC4@1224|Proteobacteria,2VHRZ@28216|Betaproteobacteria,1KKRA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Pkinase
TLS2_k127_6203541_1	864051.BurJ1DRAFT_2471	2.202e-208	664.0	COG0515@1|root,COG1639@1|root,COG0515@2|Bacteria,COG1639@2|Bacteria,1NJC4@1224|Proteobacteria,2VHRZ@28216|Betaproteobacteria,1KJ2N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KLT	HDOD domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	HDOD,Pkinase
TLS2_k127_6203541_3	1265502.KB905935_gene3104	4.349e-60	209.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,4AE6H@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
TLS2_k127_6203541_0	395495.Lcho_2806	1.945e-242	754.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2VJ2E@28216|Betaproteobacteria,1KJE2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
TLS2_k127_6221380_0	983917.RGE_16260	1.373e-219	701.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,1KJR8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
TLS2_k127_6221380_2	1265502.KB905931_gene1759	1.799e-35	138.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,4AEG8@80864|Comamonadaceae	28216|Betaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
TLS2_k127_6221380_1	395495.Lcho_1930	8.993e-50	180.0	COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,2VMQB@28216|Betaproteobacteria,1KJ73@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS2_k127_6243081_0	864051.BurJ1DRAFT_2626	1.915e-201	646.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2VGZ6@28216|Betaproteobacteria,1KK7P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,UvrD_C_2
TLS2_k127_6243081_3	525897.Dbac_0824	1.028e-13	74.0	2E9PU@1|root,333W6@2|Bacteria,1N6VC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_3
TLS2_k127_6243081_2	396595.TK90_2100	1.307e-27	114.0	COG2026@1|root,COG2026@2|Bacteria,1N80B@1224|Proteobacteria,1SDK6@1236|Gammaproteobacteria,1WZ7U@135613|Chromatiales	135613|Chromatiales	DJ	PFAM plasmid	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
TLS2_k127_6243081_1	1348657.M622_03600	1.023e-187	618.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2VI5J@28216|Betaproteobacteria,2KWW5@206389|Rhodocyclales	206389|Rhodocyclales	M	AsmA family	-	-	-	-	-	-	-	-	-	-	-	-	AsmA
TLS2_k127_6250734_4	987059.RBXJA2T_17841	0.000176	44.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,1KJ33@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
TLS2_k127_6250734_3	983917.RGE_04870	1.202e-19	97.0	2EITT@1|root,33CJ3@2|Bacteria,1NH36@1224|Proteobacteria,2VXT6@28216|Betaproteobacteria,1KMU3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
TLS2_k127_6250734_0	1245471.PCA10_15140	1.3e-188	602.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
TLS2_k127_6250734_1	1265502.KB905932_gene1798	7.015e-171	540.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2VH6G@28216|Betaproteobacteria,4ABRZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
TLS2_k127_6250734_2	1454004.AW11_00344	4.04e-169	537.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria,1KQ6G@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF3394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
TLS2_k127_6260954_0	987059.RBXJA2T_15383	7.772e-265	828.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2VHR9@28216|Betaproteobacteria,1KJDK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
TLS2_k127_6260954_1	1123392.AQWL01000002_gene2014	5.347e-20	96.0	COG3668@1|root,COG3668@2|Bacteria,1N7G9@1224|Proteobacteria	2|Bacteria	S	addiction module toxin RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
TLS2_k127_6274268_3	983917.RGE_26200	6.764e-56	201.0	COG3945@1|root,COG3945@2|Bacteria,1RIAD@1224|Proteobacteria,2VT7C@28216|Betaproteobacteria,1KM41@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
TLS2_k127_6274268_2	987059.RBXJA2T_08585	1.789e-74	253.0	COG1522@1|root,COG1522@2|Bacteria,1RI7R@1224|Proteobacteria,2VQK9@28216|Betaproteobacteria,1KKS9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
TLS2_k127_6274268_0	987059.RBXJA2T_08590	1.216e-235	736.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKRZ@28216|Betaproteobacteria,1KITC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
TLS2_k127_6274268_1	983917.RGE_26230	4.111e-139	447.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2VIFN@28216|Betaproteobacteria,1KJQY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	FAD dependent oxidoreductase	ordL	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
TLS2_k127_6279897_0	1223521.BBJX01000004_gene2510	6.835e-117	409.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VHTK@28216|Betaproteobacteria,4AD1X@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	DUF3365,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,Response_reg
TLS2_k127_6279897_3	582744.Msip34_1597	1.04e-36	161.0	COG2202@1|root,COG3614@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3614@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KKWS@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_3
TLS2_k127_6279897_1	1121413.JMKT01000011_gene2245	2.19e-98	343.0	COG4191@1|root,COG4936@1|root,COG4191@2|Bacteria,COG4936@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GAF,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PocR,Response_reg,dCache_1
TLS2_k127_6279897_2	987059.RBXJA2T_11091	3.42e-91	301.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VQ9H@28216|Betaproteobacteria,1KIX1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS2_k127_6299823_0	420662.Mpe_A1278	2.476e-174	557.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria,1KJ2K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	TIGRFAM phosphate regulon sensor kinase PhoR	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
TLS2_k127_6299823_1	983917.RGE_33140	1.126e-123	401.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,1KIU0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS2_k127_6299823_2	987059.RBXJA2T_09727	5.273e-116	381.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2VI2C@28216|Betaproteobacteria,1KIW3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
TLS2_k127_6299823_3	420662.Mpe_A1275	4.897e-58	201.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,1KK41@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
TLS2_k127_6326764_0	338966.Ppro_3139	4.591e-110	374.0	COG1639@1|root,COG3852@1|root,COG1639@2|Bacteria,COG3852@2|Bacteria,1R444@1224|Proteobacteria,42MX7@68525|delta/epsilon subdivisions,2WJHH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HDOD,HisKA
TLS2_k127_6326764_1	1198452.Jab_2c13200	4.414e-15	86.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,2W1GY@28216|Betaproteobacteria,47938@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg,SBP_bac_3
TLS2_k127_6327533_1	987059.RBXJA2T_07090	4.901e-81	271.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,1KIU7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
TLS2_k127_6327533_0	864051.BurJ1DRAFT_1305	0.0	1103.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2VHKQ@28216|Betaproteobacteria,1KITM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
TLS2_k127_6327533_3	443143.GM18_3052	6.95e-06	52.0	COG2161@1|root,COG2161@2|Bacteria,1NH4E@1224|Proteobacteria	1224|Proteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
TLS2_k127_6327533_2	870187.Thini_0223	6.968e-15	78.0	2DNNV@1|root,32YCB@2|Bacteria,1N7IN@1224|Proteobacteria,1S9V9@1236|Gammaproteobacteria,4614Q@72273|Thiotrichales	72273|Thiotrichales	S	CcdB-like toxin protein	-	-	-	ko:K19163	-	-	-	-	ko00000,ko02048	-	-	-	CcdB
TLS2_k127_6330367_2	358220.C380_08035	1.027e-61	217.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,4AAGH@80864|Comamonadaceae	28216|Betaproteobacteria	NT	chemotaxis	-	-	-	ko:K03406,ko:K03776,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3
TLS2_k127_6330367_0	420662.Mpe_A1807	7.632e-193	610.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2VIEP@28216|Betaproteobacteria,1KJJX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Aminotransferase	dapC	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS2_k127_6330367_1	420662.Mpe_A1806	1.827e-77	272.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2VHUX@28216|Betaproteobacteria,1KJWR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
TLS2_k127_6341734_3	864051.BurJ1DRAFT_0545	3.698e-17	91.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,2VIYQ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_2
TLS2_k127_6341734_0	864051.BurJ1DRAFT_0546	1.498e-290	915.0	COG1629@1|root,COG4771@2|Bacteria,1MXSN@1224|Proteobacteria,2VMER@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
TLS2_k127_6341734_5	987059.RBXJA2T_13884	8.083e-11	67.0	2A4KV@1|root,30T7K@2|Bacteria,1PCWP@1224|Proteobacteria,2W9NE@28216|Betaproteobacteria,1KMUJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2946)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2946
TLS2_k127_6341734_2	338969.Rfer_2578	1.43e-23	104.0	2BIJA@1|root,32CS2@2|Bacteria,1RHJT@1224|Proteobacteria,2VT9T@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,VPEP
TLS2_k127_6341734_1	555793.WSK_3351	1.252e-27	131.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,2U1KH@28211|Alphaproteobacteria,2K128@204457|Sphingomonadales	204457|Sphingomonadales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS2_k127_6341734_4	883126.HMPREF9710_03128	4.649e-15	75.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJBY@28216|Betaproteobacteria,476VZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS2_k127_6347177_0	987059.RBXJA2T_07623	7.614e-295	913.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,1KJPX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
TLS2_k127_6347177_1	983917.RGE_46790	3.69e-205	649.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,1KKIK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
TLS2_k127_6347384_1	864051.BurJ1DRAFT_3666	6.861e-124	402.0	COG2823@1|root,COG2823@2|Bacteria,1N42J@1224|Proteobacteria,2VK5B@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	BON,Cytidylate_kin2
TLS2_k127_6347384_0	864051.BurJ1DRAFT_3667	2.11e-200	627.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,1KNDZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
TLS2_k127_6348197_1	864051.BurJ1DRAFT_1081	1.123e-182	576.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VHRM@28216|Betaproteobacteria,1KKI6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
TLS2_k127_6348197_0	864051.BurJ1DRAFT_1080	2.147e-248	771.0	COG0683@1|root,COG0683@2|Bacteria,1MV5T@1224|Proteobacteria,2VI33@28216|Betaproteobacteria,1KJMC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TLS2_k127_6348197_3	864051.BurJ1DRAFT_1079	8.353e-149	475.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHET@28216|Betaproteobacteria,1KJ16@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
TLS2_k127_6348197_5	864051.BurJ1DRAFT_1078	4.669e-08	65.0	2EBRC@1|root,335R9@2|Bacteria,1N8E8@1224|Proteobacteria,2VVU5@28216|Betaproteobacteria,1KMI3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6348197_2	864051.BurJ1DRAFT_1077	1.126e-177	565.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VHRJ@28216|Betaproteobacteria,1KKCG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	AMP-binding enzyme	paaK_2	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
TLS2_k127_6348197_4	983917.RGE_07660	2.164e-72	250.0	COG3181@1|root,COG3181@2|Bacteria,1MW18@1224|Proteobacteria,2VHVS@28216|Betaproteobacteria,1KJ67@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	tctC4	-	-	-	-	-	-	-	-	-	-	-	TctC
TLS2_k127_6370872_2	338966.Ppro_3139	7.32e-54	196.0	COG1639@1|root,COG3852@1|root,COG1639@2|Bacteria,COG3852@2|Bacteria,1R444@1224|Proteobacteria,42MX7@68525|delta/epsilon subdivisions,2WJHH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HDOD,HisKA
TLS2_k127_6370872_0	338966.Ppro_3140	3.833e-238	759.0	COG0745@1|root,COG5001@1|root,COG0745@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,Response_reg
TLS2_k127_6370872_1	420662.Mpe_A2229	3.308e-132	431.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VKSV@28216|Betaproteobacteria,1KN7P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
TLS2_k127_6376575_1	864051.BurJ1DRAFT_2713	9.965e-121	393.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2VH9C@28216|Betaproteobacteria,1KJUE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Permease, YjgP YjgQ	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
TLS2_k127_6376575_0	987059.RBXJA2T_03758	6.315e-217	682.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria,1KJV6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
TLS2_k127_6376575_2	987059.RBXJA2T_03753	2.153e-40	158.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,2VTYC@28216|Betaproteobacteria,1KMAD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA polymerase III, chi subunit	holC	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
TLS2_k127_6379478_4	987059.RBXJA2T_08630	5.968e-132	428.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2VHYY@28216|Betaproteobacteria,1KJVC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	transport system permease	potI	-	-	ko:K11074	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	BPD_transp_1
TLS2_k127_6379478_3	864051.BurJ1DRAFT_2656	3.39e-154	491.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,2VHYC@28216|Betaproteobacteria,1KJGM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	transport system permease	potH	-	-	ko:K11075	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	BPD_transp_1
TLS2_k127_6379478_2	864051.BurJ1DRAFT_2655	2.089e-196	617.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHEJ@28216|Betaproteobacteria,1KJFE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	-	ko:K11076	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	ABC_tran,TOBE_2
TLS2_k127_6379478_1	987059.RBXJA2T_08615	1.657e-205	645.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2VJDV@28216|Betaproteobacteria,1KIYX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Required for the activity of the bacterial periplasmic transport system of putrescine	potF	-	-	ko:K11073	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	SBP_bac_8
TLS2_k127_6379478_0	987059.RBXJA2T_08610	1.865e-240	746.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VHST@28216|Betaproteobacteria,1KIYT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.113	ko:K12256	ko00330,ko01100,map00330,map01100	-	R08714	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
TLS2_k127_6385627_3	1125973.JNLC01000012_gene996	5.356e-25	118.0	COG0671@1|root,COG0671@2|Bacteria,1RDK3@1224|Proteobacteria,2U7BJ@28211|Alphaproteobacteria,3K25S@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	PFAM phosphoesterase, PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
TLS2_k127_6385627_2	1515746.HR45_13400	1.427e-53	196.0	COG0671@1|root,COG0671@2|Bacteria,1N3TP@1224|Proteobacteria,1SADV@1236|Gammaproteobacteria,2QARH@267890|Shewanellaceae	1236|Gammaproteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
TLS2_k127_6385627_0	1500890.JQNL01000001_gene243	8.82e-76	261.0	COG0125@1|root,COG0125@2|Bacteria,1R6BR@1224|Proteobacteria,1RSID@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	ATP binding	yghR	-	-	-	-	-	-	-	-	-	-	-	Thymidylate_kin
TLS2_k127_6385627_1	61647.LG71_03205	1.77e-74	259.0	COG0125@1|root,COG0125@2|Bacteria,1R4NC@1224|Proteobacteria,1RPR5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	ATP binding	yghS	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6392899_2	1249627.D779_2946	9.225e-15	78.0	2DXMK@1|root,32V3Q@2|Bacteria,1N6HJ@1224|Proteobacteria,1SB4I@1236|Gammaproteobacteria,1WZ1G@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6392899_1	1232410.KI421413_gene553	2.42e-161	530.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,42NKK@68525|delta/epsilon subdivisions,2WIQQ@28221|Deltaproteobacteria,43UIJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	ATPsynthase alpha/beta subunit N-term extension	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
TLS2_k127_6392899_0	768671.ThimaDRAFT_4706	5.64e-190	607.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,1RQ6N@1236|Gammaproteobacteria,1WX18@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
TLS2_k127_639625_0	1144319.PMI16_00176	1.3e-172	554.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2VIGQ@28216|Betaproteobacteria,476CX@75682|Oxalobacteraceae	28216|Betaproteobacteria	EH	Belongs to the TPP enzyme family	mdlC	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TLS2_k127_639625_1	365044.Pnap_1024	1.641e-78	271.0	COG0583@1|root,COG0583@2|Bacteria,1PISE@1224|Proteobacteria,2VKB4@28216|Betaproteobacteria,4ACJE@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS2_k127_6396632_0	595537.Varpa_5586	1.625e-147	471.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2VHQN@28216|Betaproteobacteria,4A9J7@80864|Comamonadaceae	28216|Betaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
TLS2_k127_6396632_2	1458427.BAWN01000039_gene2010	1.19e-79	267.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2VQ0A@28216|Betaproteobacteria,4ADF8@80864|Comamonadaceae	28216|Betaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
TLS2_k127_6396632_5	338969.Rfer_3787	3.644e-23	100.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2VVNT@28216|Betaproteobacteria,4AFHC@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
TLS2_k127_6396632_3	1268622.AVS7_03717	1.219e-44	162.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2VU2G@28216|Betaproteobacteria,4AEXY@80864|Comamonadaceae	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
TLS2_k127_6396632_1	1100721.ALKO01000008_gene2710	7.788e-92	306.0	COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2VQDH@28216|Betaproteobacteria,4ABE4@80864|Comamonadaceae	28216|Betaproteobacteria	O	Redoxin domain protein	ahp1	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	Redoxin
TLS2_k127_6396632_4	1223521.BBJX01000023_gene3068	1.901e-43	160.0	COG0454@1|root,COG0456@2|Bacteria,1PNX8@1224|Proteobacteria,2VR63@28216|Betaproteobacteria,4ADZB@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS2_k127_6404472_0	595537.Varpa_4191	2.736e-224	707.0	COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,2VKVU@28216|Betaproteobacteria,4AA8S@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Glu_cys_ligase
TLS2_k127_6404472_1	358220.C380_05105	7.405e-182	589.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,4A9RV@80864|Comamonadaceae	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	iorB2	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
TLS2_k127_6407755_3	864051.BurJ1DRAFT_1465	1.779e-154	490.0	COG1524@1|root,COG1524@2|Bacteria,1P235@1224|Proteobacteria,2VMG4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
TLS2_k127_6407755_4	864051.BurJ1DRAFT_1464	4.499e-120	392.0	28JEH@1|root,2Z98N@2|Bacteria,1RIK2@1224|Proteobacteria,2VWXE@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6407755_2	864051.BurJ1DRAFT_1463	5.985e-163	519.0	COG1099@1|root,COG1099@2|Bacteria,1MY2H@1224|Proteobacteria,2VJVP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TatD related DNase	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
TLS2_k127_6407755_0	864051.BurJ1DRAFT_1462	7.929e-221	693.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,1KK3W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.152,4.2.3.4	ko:K01735,ko:K19969	ko00400,ko00525,ko01100,ko01110,ko01130,ko01230,map00400,map00525,map01100,map01110,map01130,map01230	M00022,M00814,M00815	R03083,R10937	RC00847,RC03308	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
TLS2_k127_6407755_1	864051.BurJ1DRAFT_1461	5.459e-185	595.0	COG1082@1|root,COG1082@2|Bacteria,1NHXC@1224|Proteobacteria,2VRSG@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS2_k127_6407755_5	864051.BurJ1DRAFT_1460	6.064e-88	313.0	COG0382@1|root,COG0382@2|Bacteria,1RFNQ@1224|Proteobacteria,2W5W3@28216|Betaproteobacteria	28216|Betaproteobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
TLS2_k127_6416456_2	595537.Varpa_4877	2.626e-110	361.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2VKZV@28216|Betaproteobacteria,4ACXF@80864|Comamonadaceae	28216|Betaproteobacteria	S	Inhibitor of apoptosis-promoting Bax1	yccA	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
TLS2_k127_6416456_3	1500894.JQNN01000001_gene704	6.721e-55	209.0	COG3193@1|root,COG3193@2|Bacteria,1RGUD@1224|Proteobacteria,2VRBU@28216|Betaproteobacteria,474E6@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Haem-degrading	glcG	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Haem_degrading
TLS2_k127_6416456_0	864051.BurJ1DRAFT_2451	6.558e-203	637.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2VH9Q@28216|Betaproteobacteria,1KIZC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
TLS2_k127_6416456_1	420662.Mpe_A1262	3.248e-133	426.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,1KJ1Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
TLS2_k127_6420663_4	864051.BurJ1DRAFT_3298	3.746e-11	66.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2VJAC@28216|Betaproteobacteria,1KK3H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
TLS2_k127_6420663_1	795666.MW7_0782	4.406e-52	187.0	COG0640@1|root,COG0640@2|Bacteria,1PT7V@1224|Proteobacteria,2VSXK@28216|Betaproteobacteria	28216|Betaproteobacteria	K	regulatory protein, arsR	-	-	-	ko:K22298	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
TLS2_k127_6420663_2	292415.Tbd_2156	2.128e-50	183.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,2VTC8@28216|Betaproteobacteria,1KT25@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
TLS2_k127_6420663_0	864051.BurJ1DRAFT_3347	1.452e-83	278.0	COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,2VS0Z@28216|Betaproteobacteria	28216|Betaproteobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
TLS2_k127_6420663_3	864051.BurJ1DRAFT_3348	6.375e-32	127.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
TLS2_k127_6420730_7	95619.PM1_0208680	7.658e-08	55.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria	1224|Proteobacteria	Q	ABC transporter	iamA	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
TLS2_k127_6420730_2	748247.AZKH_p0367	8.857e-94	327.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VH5N@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
TLS2_k127_6420730_5	911008.GLAD_01750	1.782e-35	141.0	2ABSC@1|root,3118T@2|Bacteria,1RDBX@1224|Proteobacteria,1S5RV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6420730_6	2423.NA23_0209325	1.428e-15	84.0	COG0642@1|root,COG0784@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,2GCUP@200918|Thermotogae	200918|Thermotogae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,Hpt,PAS_4,PAS_9,Response_reg
TLS2_k127_6420730_3	1340493.JNIF01000003_gene2240	1.105e-66	250.0	COG4932@1|root,COG4932@2|Bacteria,3Y8ZJ@57723|Acidobacteria	57723|Acidobacteria	M	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494
TLS2_k127_6420730_1	296591.Bpro_0177	4.698e-110	361.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2VH1V@28216|Betaproteobacteria,4AAQW@80864|Comamonadaceae	28216|Betaproteobacteria	K	Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
TLS2_k127_6420730_4	983917.RGE_36410	7.555e-48	180.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS2_k127_6420730_0	983917.RGE_36420	0.0	1216.0	COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria,2WGKT@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	PAS domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS_10
TLS2_k127_642272_5	614083.AWQR01000013_gene1693	2.681e-32	125.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,4A9JJ@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
TLS2_k127_642272_3	987059.RBXJA2T_09242	1.22e-124	406.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHYN@28216|Betaproteobacteria,1KJ0T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
TLS2_k127_642272_0	983917.RGE_34040	4.706e-174	569.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,1KK9J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Oxidoreductase FAD-binding domain	ascD	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
TLS2_k127_642272_2	864051.BurJ1DRAFT_1707	4.768e-131	424.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,1KJMQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	GM	epimerase dehydratase	yeeZ	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind,TrkA_N
TLS2_k127_642272_4	983917.RGE_34020	1.08e-87	300.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2VQB1@28216|Betaproteobacteria,1KKR5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Eukaryotic integral membrane protein (DUF1751)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TLS2_k127_642272_1	983917.RGE_34010	5.303e-164	522.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VH7B@28216|Betaproteobacteria,1KJBI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS2_k127_642826_3	398767.Glov_2566	3.04e-31	139.0	COG1373@1|root,COG1373@2|Bacteria,1R7NY@1224|Proteobacteria,42WRJ@68525|delta/epsilon subdivisions,2X6IR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
TLS2_k127_642826_2	395495.Lcho_2361	3.69e-67	237.0	COG4636@1|root,COG4636@2|Bacteria,1RDIC@1224|Proteobacteria,2VS19@28216|Betaproteobacteria,1KNQ7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
TLS2_k127_642826_0	338969.Rfer_4021	7.513e-163	521.0	COG3214@1|root,COG3214@2|Bacteria,1N40B@1224|Proteobacteria,2VJY9@28216|Betaproteobacteria,4AAK3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
TLS2_k127_642826_4	159450.NH14_17890	0.000158	45.0	COG1295@1|root,COG1295@2|Bacteria,1R9UY@1224|Proteobacteria,2VJV0@28216|Betaproteobacteria,1K3VN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
TLS2_k127_642826_1	864051.BurJ1DRAFT_4718	9.64e-104	342.0	COG0561@1|root,COG0561@2|Bacteria,1R4WX@1224|Proteobacteria,2VI3C@28216|Betaproteobacteria,1KNA0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
TLS2_k127_6437739_0	864051.BurJ1DRAFT_3117	9.986e-159	505.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VIVH@28216|Betaproteobacteria,1KJKC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
TLS2_k127_6437739_1	358220.C380_02735	8.913e-131	430.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2W0I9@28216|Betaproteobacteria,4AH98@80864|Comamonadaceae	28216|Betaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
TLS2_k127_6440415_0	983917.RGE_08460	1.096e-174	553.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2VHHZ@28216|Betaproteobacteria,1KJMR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
TLS2_k127_6440415_2	1123269.NX02_14445	4.122e-114	385.0	COG2244@1|root,COG2244@2|Bacteria,1RDQG@1224|Proteobacteria,2U6PC@28211|Alphaproteobacteria,2K0Q9@204457|Sphingomonadales	204457|Sphingomonadales	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
TLS2_k127_6440415_1	1500890.JQNL01000001_gene247	1.715e-170	546.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1X3NP@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
TLS2_k127_6440415_3	1336245.JAGO01000015_gene2089	1.925e-14	76.0	COG0236@1|root,COG0236@2|Bacteria,1NHQD@1224|Proteobacteria	1224|Proteobacteria	IQ	Acyl carrier protein	AKN40_0794	-	-	-	-	-	-	-	-	-	-	-	PP-binding
TLS2_k127_6440415_4	1500890.JQNL01000001_gene245	6.623e-13	70.0	COG0702@1|root,COG0702@2|Bacteria,1R2KN@1224|Proteobacteria,1T5SD@1236|Gammaproteobacteria,1XDE2@135614|Xanthomonadales	135614|Xanthomonadales	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS2_k127_644637_2	318586.Pden_0451	8.711e-09	59.0	COG3600@1|root,COG3600@2|Bacteria,1N78U@1224|Proteobacteria,2UGBJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phage-associated protein	gepA	-	-	-	-	-	-	-	-	-	-	-	DUF4065
TLS2_k127_644637_1	1122604.JONR01000006_gene2755	1.885e-219	687.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RMJC@1236|Gammaproteobacteria,1X3WQ@135614|Xanthomonadales	135614|Xanthomonadales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
TLS2_k127_644637_0	1123256.KB907928_gene2105	0.0	1389.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1X48F@135614|Xanthomonadales	135614|Xanthomonadales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
TLS2_k127_6460665_5	1504672.669784375	0.0004736	48.0	2CIUM@1|root,34CB4@2|Bacteria,1P8HW@1224|Proteobacteria,2W56P@28216|Betaproteobacteria,4AITB@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6460665_0	1120999.JONM01000001_gene1496	3.612e-212	669.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VKYV@28216|Betaproteobacteria,2KPY2@206351|Neisseriales	206351|Neisseriales	I	Phospholipase D. Active site motifs.	-	-	2.7.8.5	ko:K00995,ko:K06131	ko00564,ko01100,map00564,map01100	-	R01801,R07390	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	PLDc_2
TLS2_k127_6460665_3	1158292.JPOE01000002_gene1945	5.186e-18	88.0	2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,2WA0T@28216|Betaproteobacteria,1KP20@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3309
TLS2_k127_6460665_4	290315.Clim_0907	3.419e-14	74.0	2DIJY@1|root,303HA@2|Bacteria,1FFP1@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6460665_2	1158292.JPOE01000002_gene1941	5.717e-28	119.0	2DNSI@1|root,32YXC@2|Bacteria,1N7K2@1224|Proteobacteria,2VVXF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6460665_1	748247.AZKH_2012	6.268e-33	132.0	COG3712@1|root,COG3712@2|Bacteria,1N941@1224|Proteobacteria,2VIKR@28216|Betaproteobacteria,2KVI1@206389|Rhodocyclales	28216|Betaproteobacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR
TLS2_k127_6460985_0	987059.RBXJA2T_11408	2.675e-100	331.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,2VJNI@28216|Betaproteobacteria,1KKPC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	ATPase MipZ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
TLS2_k127_6460985_1	983917.RGE_36810	3.753e-94	315.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2VMX4@28216|Betaproteobacteria,1KJ2T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	epsR	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS2_k127_6460985_2	987059.RBXJA2T_11398	3.493e-58	211.0	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,1KJAN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
TLS2_k127_6466933_0	983917.RGE_14510	1.186e-295	917.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,1KJ7I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS2_k127_6466933_1	420662.Mpe_A2051	6.412e-161	510.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,1KJD5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
TLS2_k127_6466933_3	983917.RGE_14470	1.054e-60	216.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2VSH8@28216|Betaproteobacteria,1KM46@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
TLS2_k127_6466933_2	420662.Mpe_A2664	8.38e-97	319.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KJEE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,HAMP,PAS_4,PAS_9,Response_reg
TLS2_k127_6481634_6	338969.Rfer_2315	9.111e-14	71.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,4A9U0@80864|Comamonadaceae	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
TLS2_k127_6481634_2	338969.Rfer_2315	7.827e-96	321.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,4A9U0@80864|Comamonadaceae	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
TLS2_k127_6481634_1	1123504.JQKD01000031_gene4552	1.436e-118	394.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2VIFF@28216|Betaproteobacteria,4AB2B@80864|Comamonadaceae	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS2_k127_6481634_3	398578.Daci_5025	9.865e-89	301.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria,4ABE8@80864|Comamonadaceae	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
TLS2_k127_6481634_0	1123504.JQKD01000031_gene4554	1.601e-156	511.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2VITB@28216|Betaproteobacteria,4AB3B@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS2_k127_6481634_4	1100721.ALKO01000003_gene2457	6.049e-77	259.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,4ADHY@80864|Comamonadaceae	28216|Betaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
TLS2_k127_6481634_5	1458427.BAWN01000019_gene1205	4.806e-54	191.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria,4A9JD@80864|Comamonadaceae	28216|Betaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
TLS2_k127_6487865_2	1265502.KB905948_gene990	1.956e-63	221.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2VSHV@28216|Betaproteobacteria,4AE4I@80864|Comamonadaceae	28216|Betaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
TLS2_k127_6487865_1	395495.Lcho_0315	1.347e-120	394.0	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,2VKM0@28216|Betaproteobacteria,1KJJU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
TLS2_k127_6487865_0	983917.RGE_45460	8.35e-158	508.0	COG0807@1|root,COG0807@2|Bacteria,1MWUM@1224|Proteobacteria,2VJRX@28216|Betaproteobacteria,1KJRK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Protein of unknown function (DUF1688)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1688
TLS2_k127_6487865_3	864051.BurJ1DRAFT_1726	1.308e-39	147.0	COG0807@1|root,COG0807@2|Bacteria,1PQ5Y@1224|Proteobacteria,2VJ66@28216|Betaproteobacteria,1KJ1N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	GTP cyclohydrolase N terminal	ribA	-	-	-	-	-	-	-	-	-	-	-	GTP_CH_N,GTP_cyclohydro2
TLS2_k127_6493502_2	314278.NB231_02798	1.469e-15	88.0	COG1196@1|root,COG1196@2|Bacteria,1RAVP@1224|Proteobacteria,1S30D@1236|Gammaproteobacteria,1WY5E@135613|Chromatiales	135613|Chromatiales	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6493502_1	1207076.ALAT01000058_gene593	9.116e-53	206.0	COG0500@1|root,COG4122@1|root,COG0500@2|Bacteria,COG4122@2|Bacteria,1QMHT@1224|Proteobacteria,1SFAE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6493502_0	266809.PM03_16540	5.628e-138	466.0	COG1215@1|root,COG1215@2|Bacteria,1MU5I@1224|Proteobacteria,2U4NG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS2_k127_6506089_1	983917.RGE_32990	1.007e-54	193.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,1KM4W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
TLS2_k127_6506089_0	983917.RGE_32980	9.831e-93	308.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2VJVJ@28216|Betaproteobacteria,1KJ29@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
TLS2_k127_6506089_2	395495.Lcho_0008	1.067e-23	107.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2VHVQ@28216|Betaproteobacteria,1KN1U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	L,D-transpeptidase catalytic domain	ycbB	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
TLS2_k127_6513463_4	1454004.AW11_00959	8.849e-11	63.0	2DSX7@1|root,33HSU@2|Bacteria,1NGYV@1224|Proteobacteria,2W4DI@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6513463_3	338969.Rfer_3394	8.538e-81	285.0	COG3115@1|root,COG3115@2|Bacteria,1QWGJ@1224|Proteobacteria,2WGZ3@28216|Betaproteobacteria,4AH94@80864|Comamonadaceae	28216|Betaproteobacteria	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6513463_2	1458427.BAWN01000006_gene361	3.62e-100	332.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2VH1V@28216|Betaproteobacteria,4AAQW@80864|Comamonadaceae	28216|Betaproteobacteria	K	Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
TLS2_k127_6513463_1	1122604.JONR01000008_gene2173	1.586e-116	383.0	COG3437@1|root,COG3437@2|Bacteria,1QYY0@1224|Proteobacteria,1S16I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS2_k127_6513463_0	864051.BurJ1DRAFT_3374	7.728e-245	769.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJNX@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
TLS2_k127_6515763_4	1121937.AUHJ01000009_gene1516	1.994e-98	363.0	COG0438@1|root,COG0438@2|Bacteria,1R2WM@1224|Proteobacteria,1RY41@1236|Gammaproteobacteria,469G9@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS2_k127_6515763_2	864051.BurJ1DRAFT_3166	1.074e-136	482.0	COG0438@1|root,COG0438@2|Bacteria,1R2WM@1224|Proteobacteria,2VKPJ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS2_k127_6515763_5	522306.CAP2UW1_1432	8.802e-81	306.0	COG1305@1|root,COG1305@2|Bacteria,1RGH2@1224|Proteobacteria	1224|Proteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
TLS2_k127_6515763_0	522306.CAP2UW1_1431	1.942e-223	700.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VMX7@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	algD	-	1.1.1.132	ko:K00066	ko00051,ko00520,ko02020,map00051,map00520,map02020	-	R00880	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TLS2_k127_6515763_1	864051.BurJ1DRAFT_3181	4.61e-205	657.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria,1KMBZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
TLS2_k127_6515763_3	522306.CAP2UW1_1424	2.178e-103	341.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS2_k127_6519750_2	983917.RGE_00500	9.106e-47	173.0	COG4555@1|root,COG4555@2|Bacteria,1QU2T@1224|Proteobacteria,2VPXN@28216|Betaproteobacteria,1KK76@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CP	ATPases associated with a variety of cellular activities	natA	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
TLS2_k127_6519750_0	987059.RBXJA2T_03958	2.098e-177	570.0	COG0596@1|root,COG2267@1|root,COG0596@2|Bacteria,COG2267@2|Bacteria,1R6KU@1224|Proteobacteria,2VMJU@28216|Betaproteobacteria,1KIYK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
TLS2_k127_6519750_3	338969.Rfer_0010	6.263e-43	173.0	COG0278@1|root,COG0278@2|Bacteria,1RKVH@1224|Proteobacteria,2WGD8@28216|Betaproteobacteria,4AEKZ@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
TLS2_k127_6519750_1	983917.RGE_00470	5.301e-94	316.0	COG0526@1|root,COG0526@2|Bacteria,1MWU8@1224|Proteobacteria,2VPNK@28216|Betaproteobacteria,1KNFX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2,Thioredoxin_7
TLS2_k127_6533513_2	1265502.KB905938_gene2500	6.731e-87	289.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria,4A9WD@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
TLS2_k127_6533513_1	987059.RBXJA2T_11648	4.943e-91	304.0	COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,2VHI4@28216|Betaproteobacteria,1KJ0X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
TLS2_k127_6533513_4	983917.RGE_42470	2.64e-52	194.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2VSCX@28216|Betaproteobacteria,1KM0C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
TLS2_k127_6533513_5	983917.RGE_42460	5.06e-24	116.0	2E58M@1|root,33011@2|Bacteria,1NFX1@1224|Proteobacteria,2VWUP@28216|Betaproteobacteria,1KMKA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6533513_0	987059.RBXJA2T_11668	7.357e-109	359.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2VP72@28216|Betaproteobacteria,1KK3Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
TLS2_k127_6533513_3	987059.RBXJA2T_11673	1.809e-52	186.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria,1KJST@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TLS2_k127_6537982_2	420662.Mpe_A1890	5.097e-154	491.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2VJHD@28216|Betaproteobacteria,1KK1M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS2_k127_6537982_0	987059.RBXJA2T_08565	2.021e-256	795.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,2VHWS@28216|Betaproteobacteria,1KJQD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
TLS2_k127_6537982_1	864051.BurJ1DRAFT_1714	7.191e-167	526.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,1KJ5H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TLS2_k127_654883_4	987059.RBXJA2T_12307	5.082e-15	76.0	COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,2VIM5@28216|Betaproteobacteria,1KJWJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
TLS2_k127_654883_3	987059.RBXJA2T_12312	1.84e-36	147.0	COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,2VU0N@28216|Betaproteobacteria,1KNN8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
TLS2_k127_654883_0	987059.RBXJA2T_12322	2.258e-140	453.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,1KK8I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Tyrosine recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
TLS2_k127_654883_2	983917.RGE_14900	5.41e-130	418.0	COG0765@1|root,COG0765@2|Bacteria,1P3W6@1224|Proteobacteria,2VKIE@28216|Betaproteobacteria,1KJTD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
TLS2_k127_654883_1	983917.RGE_14910	1.007e-132	428.0	COG0834@1|root,COG0834@2|Bacteria,1MV3Q@1224|Proteobacteria,2VJ9K@28216|Betaproteobacteria,1KK0H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	ET	Ligated ion channel L-glutamate- and glycine-binding site	-	-	-	ko:K02030,ko:K10036	ko02010,map02010	M00227,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.2	-	-	SBP_bac_3
TLS2_k127_6565308_0	983917.RGE_21750	1.189e-130	421.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2VHU1@28216|Betaproteobacteria,1KKE5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS2_k127_6565308_1	420662.Mpe_A3051	2.527e-97	325.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2VHP3@28216|Betaproteobacteria,1KKA2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS2_k127_656765_1	983917.RGE_40920	2.214e-112	366.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,1KJ6P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
TLS2_k127_656765_0	983917.RGE_40900	5.661e-142	459.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2VI51@28216|Betaproteobacteria,1KJ5N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS2_k127_656765_2	983917.RGE_40890	6.659e-102	336.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2VIZ2@28216|Betaproteobacteria,1KJ06@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	HAD-hyrolase-like	ppaX	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
TLS2_k127_6572429_1	987059.RBXJA2T_10359	1.339e-88	298.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,1KJDU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
TLS2_k127_6572429_2	983917.RGE_31960	5.975e-61	213.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2VSCK@28216|Betaproteobacteria,1KM2Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
TLS2_k127_6572429_0	614083.AWQR01000031_gene2589	9.457e-118	380.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2VI2Y@28216|Betaproteobacteria,4AAFF@80864|Comamonadaceae	28216|Betaproteobacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1,3.1.11.6	ko:K03601,ko:K04564	ko03430,ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map03430,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Sod_Fe_C,Sod_Fe_N
TLS2_k127_6572429_3	983917.RGE_31970	9.416e-14	76.0	COG0605@1|root,COG1570@1|root,COG0605@2|Bacteria,COG1570@2|Bacteria,1MVW2@1224|Proteobacteria,2VI2Y@28216|Betaproteobacteria,1KPHW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	LP	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	sodB	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1,3.1.11.6	ko:K03601,ko:K04564	ko03430,ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map03430,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Sod_Fe_C,Sod_Fe_N
TLS2_k127_6597952_1	543728.Vapar_2683	2.654e-120	401.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VIA5@28216|Betaproteobacteria,4AANU@80864|Comamonadaceae	28216|Betaproteobacteria	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
TLS2_k127_6597952_0	864051.BurJ1DRAFT_3780	3.186e-232	725.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2VIJY@28216|Betaproteobacteria,1KJ6Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF853)	yjgR	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
TLS2_k127_6600016_8	1122604.JONR01000017_gene4339	1.035e-34	135.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,1S2Z2@1236|Gammaproteobacteria,1X56C@135614|Xanthomonadales	135614|Xanthomonadales	Q	DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
TLS2_k127_6600016_7	1121438.JNJA01000002_gene3546	1.899e-52	195.0	COG1437@1|root,COG1437@2|Bacteria,1RJYE@1224|Proteobacteria,42ZWS@68525|delta/epsilon subdivisions,2WVBV@28221|Deltaproteobacteria,2MBNM@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
TLS2_k127_6600016_2	983917.RGE_01810	1.636e-127	418.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2W0NK@28216|Betaproteobacteria,1KMZP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
TLS2_k127_6600016_3	983917.RGE_01820	5.107e-115	376.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2W19X@28216|Betaproteobacteria,1KNCJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
TLS2_k127_6600016_6	543728.Vapar_0482	1.376e-57	209.0	COG3631@1|root,COG3631@2|Bacteria,1RDED@1224|Proteobacteria,2VS1C@28216|Betaproteobacteria,4AE6M@80864|Comamonadaceae	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
TLS2_k127_6600016_1	864051.BurJ1DRAFT_0142	6.343e-180	575.0	COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria,2VPBZ@28216|Betaproteobacteria,1KMZE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6600016_4	1218074.BAXZ01000025_gene4489	6.6e-87	291.0	COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,2VQ03@28216|Betaproteobacteria,1K2RR@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_C_3,GST_N,GST_N_3
TLS2_k127_6600016_5	987059.RBXJA2T_18974	4.137e-61	215.0	COG1764@1|root,COG1764@2|Bacteria,1RI5C@1224|Proteobacteria,2WFNG@28216|Betaproteobacteria,1KM7D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
TLS2_k127_6600016_9	987059.RBXJA2T_18984	2.15e-27	115.0	COG2916@1|root,COG2916@2|Bacteria,1NB7Y@1224|Proteobacteria,2VVZE@28216|Betaproteobacteria,1KMPR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	H-NS histone family	-	-	-	ko:K03746	-	-	-	-	ko00000,ko03036,ko03400	-	-	-	Histone_HNS
TLS2_k127_6600016_0	987059.RBXJA2T_18989	5.532e-238	742.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2VICH@28216|Betaproteobacteria,1KITK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
TLS2_k127_6609697_2	1123393.KB891316_gene2056	9.538e-77	259.0	COG0726@1|root,COG0726@2|Bacteria,1PJQG@1224|Proteobacteria,2VIG8@28216|Betaproteobacteria,1KS0R@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
TLS2_k127_6609697_0	159087.Daro_4185	1.779e-206	653.0	COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,2VJR3@28216|Betaproteobacteria,2KU9C@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS2_k127_6609697_1	1123393.KB891316_gene2058	1.389e-119	406.0	COG0304@1|root,COG0304@2|Bacteria,1NP8M@1224|Proteobacteria,2VJDN@28216|Betaproteobacteria,1KSZX@119069|Hydrogenophilales	119069|Hydrogenophilales	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2
TLS2_k127_6609697_3	1121035.AUCH01000022_gene3223	3.416e-52	196.0	COG4706@1|root,COG4706@2|Bacteria,1RIH4@1224|Proteobacteria,2VT0K@28216|Betaproteobacteria,2KWT5@206389|Rhodocyclales	206389|Rhodocyclales	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6609697_4	1123393.KB891316_gene2060	5.824e-17	83.0	COG1028@1|root,COG1028@2|Bacteria,1MUPY@1224|Proteobacteria,2VK19@28216|Betaproteobacteria,1KSUK@119069|Hydrogenophilales	119069|Hydrogenophilales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
TLS2_k127_6623395_1	535289.Dtpsy_2795	9.05e-31	128.0	2DNW4@1|root,32ZGA@2|Bacteria,1N7ZK@1224|Proteobacteria,2VWJH@28216|Betaproteobacteria,4AF49@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3306
TLS2_k127_6623395_0	395495.Lcho_3732	0.0	1053.0	COG1148@1|root,COG1148@2|Bacteria,1QUQG@1224|Proteobacteria,2VMBE@28216|Betaproteobacteria,1KJCC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7
TLS2_k127_6623395_2	395495.Lcho_3733	5.09e-19	88.0	COG3381@1|root,COG3381@2|Bacteria,1MWWM@1224|Proteobacteria,2VJ39@28216|Betaproteobacteria,1KKHR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Nitrate reductase delta subunit	torD	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
TLS2_k127_6633465_4	595537.Varpa_2451	5.986e-10	61.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHB0@28216|Betaproteobacteria,4AAPD@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
TLS2_k127_6633465_2	1424334.W822_03065	2.752e-117	381.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,3T2YJ@506|Alcaligenaceae	28216|Betaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
TLS2_k127_6633465_0	1286631.X805_25050	1.676e-154	497.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,2VPAX@28216|Betaproteobacteria	28216|Betaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
TLS2_k127_6633465_3	663932.KB902575_gene1614	1.024e-99	328.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria,2JRQP@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
TLS2_k127_6633465_1	420662.Mpe_A3317	8.678e-131	422.0	COG0583@1|root,COG0583@2|Bacteria,1MUNN@1224|Proteobacteria,2VKER@28216|Betaproteobacteria,1KKXA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS2_k127_6642129_0	29581.BW37_00934	1.626e-144	460.0	COG0543@1|root,COG0543@2|Bacteria,1QTSK@1224|Proteobacteria,2VH0M@28216|Betaproteobacteria	28216|Betaproteobacteria	CH	oxidoreductase FAD NAD(P)-binding domain protein	fpr	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
TLS2_k127_6642129_1	864051.BurJ1DRAFT_3464	7.768e-104	346.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VJCT@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS2_k127_6647287_1	983917.RGE_41950	2.859e-66	226.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2VHEK@28216|Betaproteobacteria,1KJZT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
TLS2_k127_6647287_2	420662.Mpe_A0714	4.406e-52	187.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,1KM9T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	glpE	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
TLS2_k127_6647287_3	987059.RBXJA2T_00140	2.063e-38	146.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,1KM9Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
TLS2_k127_6647287_0	987059.RBXJA2T_00135	3.719e-75	255.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2VQ1Q@28216|Betaproteobacteria,1KKTQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
TLS2_k127_6647287_4	123899.JPQP01000020_gene1977	5.986e-10	61.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2VJ91@28216|Betaproteobacteria,3T2QZ@506|Alcaligenaceae	28216|Betaproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
TLS2_k127_6653007_6	987059.RBXJA2T_07693	3.73e-117	386.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2VK0Y@28216|Betaproteobacteria,1KJT7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
TLS2_k127_6653007_7	420662.Mpe_A0081	1.239e-79	270.0	COG2891@1|root,COG2891@2|Bacteria,1RBNF@1224|Proteobacteria,2VQQ3@28216|Betaproteobacteria,1KKT1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Rod shape-determining protein mreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
TLS2_k127_6653007_0	887062.HGR_08379	6.228e-252	797.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria,4AAEW@80864|Comamonadaceae	28216|Betaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
TLS2_k127_6653007_4	420662.Mpe_A0079	8.215e-174	572.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2VH8Q@28216|Betaproteobacteria,1KJS3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
TLS2_k127_6653007_1	983917.RGE_46620	2.895e-200	635.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2WGRW@28216|Betaproteobacteria,1KK18@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	two-component sensor kinase	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
TLS2_k127_6653007_5	987059.RBXJA2T_13539	3.087e-128	412.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VI0W@28216|Betaproteobacteria,1KK1U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	PFAM response regulator receiver	basR_3	-	-	ko:K02483,ko:K07666,ko:K07774	ko02020,ko02024,map02020,map02024	M00453,M00457	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS2_k127_6653007_3	864051.BurJ1DRAFT_4952	2.127e-198	624.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria,1KIVV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
TLS2_k127_6653007_8	987059.RBXJA2T_13529	7.433e-59	207.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,2VTYZ@28216|Betaproteobacteria,1KMD0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
TLS2_k127_6653007_2	987059.RBXJA2T_09879	5.283e-200	630.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria,1KIU3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
TLS2_k127_6673743_0	983917.RGE_32240	0.0	1563.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KJ2M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	AcrB/AcrD/AcrF family	acrB	-	-	ko:K18138,ko:K18146,ko:K18902	ko01501,ko01503,map01501,map01503	M00647,M00649,M00698,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.40	-	-	ACR_tran
TLS2_k127_6673743_1	365044.Pnap_2885	9.097e-141	466.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,4AADJ@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
TLS2_k127_6673743_2	1286631.X805_01320	2.12e-73	252.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,1KKJF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	Abhydrolase_1,MafB19-deam,TfoX_C
TLS2_k127_6697975_0	1191523.MROS_1774	6.047e-298	930.0	COG0243@1|root,COG0243@2|Bacteria	2|Bacteria	C	molybdopterin cofactor binding	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
TLS2_k127_6710321_1	983917.RGE_35510	1.356e-125	408.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,1KJSS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
TLS2_k127_6710321_0	983917.RGE_35500	8.814e-201	631.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2VHMW@28216|Betaproteobacteria,1KJQ3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KLT	Serine threonine protein kinase	spkD	-	-	-	-	-	-	-	-	-	-	-	Pkinase
TLS2_k127_6719229_0	375286.mma_3355	3.514e-258	838.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,472QP@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Neisseria PilC beta-propeller domain	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
TLS2_k127_6719229_4	395495.Lcho_2908	8.123e-33	143.0	COG4726@1|root,COG4726@2|Bacteria,1N9CE@1224|Proteobacteria,2VWPP@28216|Betaproteobacteria,1KMT5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6719229_1	395495.Lcho_2907	1.812e-73	261.0	COG4966@1|root,COG4966@2|Bacteria,1RH2G@1224|Proteobacteria,2VT5C@28216|Betaproteobacteria,1KMMA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Type IV Pilus-assembly protein W	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
TLS2_k127_6719229_5	1286631.X805_20180	1.91e-23	105.0	COG4967@1|root,COG4967@2|Bacteria,1N7AC@1224|Proteobacteria,2VW8B@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
TLS2_k127_6719229_3	395495.Lcho_2905	2.874e-41	166.0	COG4970@1|root,COG4970@2|Bacteria,1NA9B@1224|Proteobacteria,2VWAB@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
TLS2_k127_6719229_2	395495.Lcho_2904	3.131e-43	166.0	COG4968@1|root,COG4968@2|Bacteria,1MZZW@1224|Proteobacteria,2VU8H@28216|Betaproteobacteria,1KMKX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
TLS2_k127_6720921_3	358220.C380_13680	8.177e-154	495.0	COG1638@1|root,COG1638@2|Bacteria,1MVYB@1224|Proteobacteria,2VIQ9@28216|Betaproteobacteria,4AA41@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP dicarboxylate transporter- DctP subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctP
TLS2_k127_6720921_4	391735.Veis_2338	5.748e-57	220.0	COG3090@1|root,COG3090@2|Bacteria,1N01Z@1224|Proteobacteria,2VRI7@28216|Betaproteobacteria,4ADWU@80864|Comamonadaceae	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporter DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
TLS2_k127_6720921_2	1458275.AZ34_13040	4.927e-216	677.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VJME@28216|Betaproteobacteria,4AAMJ@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	siaT_7	-	-	-	-	-	-	-	-	-	-	-	DctM
TLS2_k127_6720921_0	983917.RGE_39180	1.591e-313	980.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,1KJJ6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
TLS2_k127_6720921_1	426114.THI_2003	1.018e-216	679.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2VK6J@28216|Betaproteobacteria,1KMID@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
TLS2_k127_6720921_5	1144319.PMI16_01881	6.171e-47	181.0	COG3209@1|root,COG3209@2|Bacteria,1R1SB@1224|Proteobacteria,2W3D6@28216|Betaproteobacteria	1224|Proteobacteria	M	Salmonella virulence plasmid 65kDa B protein	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS2_k127_6728407_1	983917.RGE_00010	6.625e-238	742.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2VHH0@28216|Betaproteobacteria,1KIWU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
TLS2_k127_6728407_2	987059.RBXJA2T_03798	1.86e-199	625.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2VH9B@28216|Betaproteobacteria,1KJ8A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
TLS2_k127_6728407_0	864051.BurJ1DRAFT_0003	0.0	1439.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2VI8N@28216|Betaproteobacteria,1KJTT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TLS2_k127_675687_2	85643.Tmz1t_0368	3.028e-85	287.0	COG3464@1|root,COG3464@2|Bacteria,1MV5J@1224|Proteobacteria,2VP6A@28216|Betaproteobacteria	28216|Betaproteobacteria	L	transposase IS204 IS1001 IS1096 IS1165 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
TLS2_k127_675687_6	1265502.KB905984_gene22	0.0001414	46.0	2CA65@1|root,2Z8DY@2|Bacteria,1MXGI@1224|Proteobacteria,2VM06@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_675687_0	864051.BurJ1DRAFT_3572	1.263e-311	958.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,1KJNP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
TLS2_k127_675687_1	987059.RBXJA2T_14696	8.007e-258	815.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria,1KIYR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
TLS2_k127_675687_3	983917.RGE_30980	8.661e-42	160.0	2BCK1@1|root,32662@2|Bacteria,1RHH4@1224|Proteobacteria,2VSPG@28216|Betaproteobacteria,1KMDU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
TLS2_k127_675687_4	983917.RGE_30990	8.732e-26	110.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,2VVNX@28216|Betaproteobacteria,1KMJQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0125 (RnfH) family	rnfH	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
TLS2_k127_6757216_0	864051.BurJ1DRAFT_2624	2.316e-226	718.0	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,2VHW7@28216|Betaproteobacteria,1KK73@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
TLS2_k127_6757216_1	864051.BurJ1DRAFT_2625	1.337e-179	578.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2VI92@28216|Betaproteobacteria,1KKD0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
TLS2_k127_6759193_0	395495.Lcho_3605	1.535e-245	764.0	COG0001@1|root,COG0001@2|Bacteria,1QVPQ@1224|Proteobacteria,2WHQE@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS2_k127_6759193_2	395495.Lcho_3606	3.08e-85	290.0	28MZJ@1|root,2ZB69@2|Bacteria,1R6VF@1224|Proteobacteria,2VR02@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6759193_1	395495.Lcho_3607	9.48e-144	470.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VJ5X@28216|Betaproteobacteria,1KIZ6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS2_k127_6759193_3	398578.Daci_5753	3.096e-32	132.0	COG5607@1|root,COG5607@2|Bacteria,1QTX6@1224|Proteobacteria,2W1SX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
TLS2_k127_676032_0	296591.Bpro_1465	1.111e-146	471.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2VJWK@28216|Betaproteobacteria,4AAJ1@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
TLS2_k127_676032_1	1366050.N234_10855	2.568e-100	344.0	COG3181@1|root,COG3181@2|Bacteria,1MY36@1224|Proteobacteria,2VJK1@28216|Betaproteobacteria,1KBZJ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
TLS2_k127_676032_3	358220.C380_00645	3.867e-52	192.0	COG1309@1|root,COG1309@2|Bacteria,1MYHJ@1224|Proteobacteria	1224|Proteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS2_k127_676032_2	1003200.AXXA_22040	3.93e-67	235.0	COG1309@1|root,COG1309@2|Bacteria,1N1Q3@1224|Proteobacteria,2VNVW@28216|Betaproteobacteria,3T8A8@506|Alcaligenaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS2_k127_6773562_1	596154.Alide2_4028	6.178e-100	332.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2VIBW@28216|Betaproteobacteria,4A9M7@80864|Comamonadaceae	28216|Betaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
TLS2_k127_6773562_2	1122603.ATVI01000006_gene229	9.846e-17	94.0	28I8G@1|root,2Z8BA@2|Bacteria,1MWYF@1224|Proteobacteria,1RTN9@1236|Gammaproteobacteria,1X83I@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6773562_0	1100720.ALKN01000037_gene1892	6.63e-179	562.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VH05@28216|Betaproteobacteria,4AC69@80864|Comamonadaceae	28216|Betaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
TLS2_k127_6776986_1	395495.Lcho_1697	5.397e-77	261.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VI0W@28216|Betaproteobacteria,1KN9T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS2_k127_6776986_0	395495.Lcho_1696	9.615e-163	529.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2WGRW@28216|Betaproteobacteria,1KNBP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Two-component sensor kinase N-terminal	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
TLS2_k127_6790485_3	864051.BurJ1DRAFT_1438	3.608e-91	304.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2VHTD@28216|Betaproteobacteria,1KK1N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Probable molybdopterin binding domain	yfaY	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
TLS2_k127_6790485_2	987059.RBXJA2T_16837	9.023e-101	336.0	COG2981@1|root,COG2981@2|Bacteria,1Q181@1224|Proteobacteria,2VN29@28216|Betaproteobacteria,1KKAS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	-	-	-	-	-	-	-	-	-	EI24
TLS2_k127_6790485_0	864051.BurJ1DRAFT_1436	2.05e-146	471.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2VJE7@28216|Betaproteobacteria,1KJHK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
TLS2_k127_6790485_1	420662.Mpe_A2080	6.205e-110	364.0	COG0726@1|root,COG0726@2|Bacteria,1MX3V@1224|Proteobacteria,2VJVH@28216|Betaproteobacteria,1KKEP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Polysaccharide deacetylase	pdaA	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
TLS2_k127_6790485_4	1504672.669786956	9.377e-13	68.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2VKXA@28216|Betaproteobacteria,4ACF0@80864|Comamonadaceae	28216|Betaproteobacteria	S	40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
TLS2_k127_6793554_3	305700.B447_01301	3.735e-12	66.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH5A@28216|Betaproteobacteria,2KV7J@206389|Rhodocyclales	206389|Rhodocyclales	C	glycolate oxidase subunit GlcD	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
TLS2_k127_6793554_0	535289.Dtpsy_2969	2.069e-108	372.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VZ6J@28216|Betaproteobacteria,4AH3Z@80864|Comamonadaceae	28216|Betaproteobacteria	NT	Chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
TLS2_k127_6793554_1	983917.RGE_15720	2.97e-40	152.0	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2VSCN@28216|Betaproteobacteria,1KM7X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1178
TLS2_k127_6793846_2	535289.Dtpsy_2953	9.202e-05	45.0	2E4QE@1|root,32ZIZ@2|Bacteria,1NCEP@1224|Proteobacteria,2VU6H@28216|Betaproteobacteria,4AFIG@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_6793846_1	395495.Lcho_0942	3.042e-93	309.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2VQ7P@28216|Betaproteobacteria,1KJ9Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Cobalamin adenosyltransferase	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
TLS2_k127_6793846_0	420662.Mpe_A3774	3.108e-175	555.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VI85@28216|Betaproteobacteria,1KJYQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	FAD linked oxidases, C-terminal domain	dld	-	1.1.2.4,1.1.5.12	ko:K00102,ko:K03777	ko00620,ko01120,map00620,map01120	-	R00197,R00704,R11591	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
TLS2_k127_6794043_0	987059.RBXJA2T_02627	4.799e-218	682.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,1KJ17@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA topoisomerase III	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	SWIB,Topoisom_bac,Toprim,Toprim_Crpt
TLS2_k127_6794043_3	987059.RBXJA2T_02622	1.15e-28	118.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,2VWDY@28216|Betaproteobacteria,1KMNJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
TLS2_k127_6794043_2	864051.BurJ1DRAFT_0860	1.063e-101	346.0	COG0679@1|root,COG0679@2|Bacteria,1MY23@1224|Proteobacteria,2VI9B@28216|Betaproteobacteria,1KJU6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
TLS2_k127_6794043_1	864051.BurJ1DRAFT_0861	1.704e-207	654.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria,1KK40@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS2_k127_67969_4	983917.RGE_13200	3.03e-07	57.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VIVH@28216|Betaproteobacteria,1KJKC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
TLS2_k127_67969_1	987059.RBXJA2T_08745	6.126e-156	505.0	COG2358@1|root,COG2358@2|Bacteria,1PNJV@1224|Proteobacteria,2VI8H@28216|Betaproteobacteria,1KKCI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
TLS2_k127_67969_0	1123367.C666_11810	1.139e-172	550.0	COG0075@1|root,COG0075@2|Bacteria,1PM38@1224|Proteobacteria,2VHNM@28216|Betaproteobacteria,2KVAR@206389|Rhodocyclales	206389|Rhodocyclales	E	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
TLS2_k127_67969_2	1265502.KB905934_gene3237	3.792e-151	482.0	COG3483@1|root,COG3483@2|Bacteria,1MW68@1224|Proteobacteria,2VJG3@28216|Betaproteobacteria,4ACUT@80864|Comamonadaceae	28216|Betaproteobacteria	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
TLS2_k127_67969_3	1265502.KB905934_gene3236	7.939e-137	441.0	COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,2VIP0@28216|Betaproteobacteria,4AAXE@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
TLS2_k127_6826486_2	977880.pRALTA_0066	6.8e-06	53.0	COG5126@1|root,COG5126@2|Bacteria,1NXMW@1224|Proteobacteria,2W3NV@28216|Betaproteobacteria,1KB0P@119060|Burkholderiaceae	28216|Betaproteobacteria	DTZ	Ca2 -binding protein (EF-Hand superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
TLS2_k127_6826486_0	420662.Mpe_A3793	1.231e-305	954.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,2VP2B@28216|Betaproteobacteria,1KJK7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Peptidase C39 family	cvaB	-	-	ko:K13409	ko02010,ko04626,map02010,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.110	-	-	ABC_membrane,ABC_tran,Peptidase_C39
TLS2_k127_6826486_1	420662.Mpe_A3794	2.901e-113	379.0	COG0845@1|root,COG0845@2|Bacteria,1R3R4@1224|Proteobacteria,2VJDS@28216|Betaproteobacteria,1KM1W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	HlyD family secretion protein	cvaA	-	-	ko:K13408	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
TLS2_k127_6830363_2	29581.BW37_04785	1.529e-18	89.0	COG1879@1|root,COG1879@2|Bacteria,1MV17@1224|Proteobacteria,2VTNC@28216|Betaproteobacteria,47281@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
TLS2_k127_6830363_0	395495.Lcho_3287	8.042e-100	336.0	COG1737@1|root,COG1737@2|Bacteria,1MW2B@1224|Proteobacteria,2VPMG@28216|Betaproteobacteria,1KNM1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
TLS2_k127_6830363_1	395495.Lcho_3283	7.312e-57	201.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,2VKZT@28216|Betaproteobacteria,1KN28@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	iolG	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS2_k127_6851024_4	296591.Bpro_2805	3.292e-75	254.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2VP2Q@28216|Betaproteobacteria,4AAQA@80864|Comamonadaceae	28216|Betaproteobacteria	C	formate dehydrogenase, alpha subunit	fdhA1	-	1.17.1.9,1.17.99.7	ko:K00123,ko:K22015	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
TLS2_k127_6851024_5	991905.SL003B_2629	1.503e-64	230.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,2U5HS@28211|Alphaproteobacteria,4BS0C@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	F	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Erythro_esteras,Pribosyltran
TLS2_k127_6851024_2	338969.Rfer_1106	2.613e-189	602.0	COG5520@1|root,COG5520@2|Bacteria,1N9T9@1224|Proteobacteria,2VTEK@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Glycosyl hydrolase family 30 beta sandwich domain	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
TLS2_k127_6851024_0	1229487.AMYW01000029_gene2874	1.24e-322	1012.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia,2NSID@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
TLS2_k127_6851024_1	338969.Rfer_1114	9.899e-216	698.0	COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,2VSIK@28216|Betaproteobacteria,4AHWT@80864|Comamonadaceae	28216|Betaproteobacteria	E	Tryptophan halogenase	-	-	1.14.19.9	ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
TLS2_k127_6851024_3	338969.Rfer_1107	4.369e-133	433.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VGZM@28216|Betaproteobacteria,4ABW2@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
TLS2_k127_688506_0	522306.CAP2UW1_0142	2.219e-113	376.0	COG0628@1|root,COG0628@2|Bacteria,1MWKB@1224|Proteobacteria,2VSBS@28216|Betaproteobacteria,1KR04@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS2_k127_688506_2	1042209.HK44_005135	2.848e-16	85.0	297ZI@1|root,2ZV5N@2|Bacteria,1P53M@1224|Proteobacteria,1RVN4@1236|Gammaproteobacteria,1YU6E@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_688506_1	1151127.KB906326_gene761	3.279e-36	143.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN5K@1236|Gammaproteobacteria,1YSYV@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS2_k127_6888541_0	420662.Mpe_A3180	9.026e-276	852.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VHGU@28216|Betaproteobacteria,1KKFU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
TLS2_k127_6888541_1	864051.BurJ1DRAFT_4213	1.127e-193	614.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,2VH9M@28216|Betaproteobacteria,1KJTP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3,OmpA
TLS2_k127_6888541_2	296591.Bpro_1244	2.217e-30	128.0	COG5488@1|root,COG5488@2|Bacteria,1N5Z9@1224|Proteobacteria,2VU1W@28216|Betaproteobacteria,4AE03@80864|Comamonadaceae	28216|Betaproteobacteria	S	Integral membrane protein (DUF2244)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2244
TLS2_k127_6888541_3	987059.RBXJA2T_00110	3.298e-11	64.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,1KPE4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Methyltransferase domain	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
TLS2_k127_6891431_0	420662.Mpe_A3046	0.0	1373.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2VIEJ@28216|Betaproteobacteria,1KJY8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
TLS2_k127_6891431_3	983917.RGE_14000	1.243e-66	233.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2VSEP@28216|Betaproteobacteria,1KKU6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
TLS2_k127_6891431_2	395495.Lcho_1233	1.412e-114	377.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2VK3K@28216|Betaproteobacteria,1KJI4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
TLS2_k127_6891431_4	1223521.BBJX01000005_gene1974	1.543e-65	229.0	COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,2VRCS@28216|Betaproteobacteria,4AE1P@80864|Comamonadaceae	28216|Betaproteobacteria	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_2
TLS2_k127_6891431_1	395495.Lcho_0008	5.328e-133	433.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2VHVQ@28216|Betaproteobacteria,1KN1U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	L,D-transpeptidase catalytic domain	ycbB	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
TLS2_k127_6904752_0	435908.IDSA_04095	1.898e-163	516.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,1RQ01@1236|Gammaproteobacteria,2QGKI@267893|Idiomarinaceae	1236|Gammaproteobacteria	P	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
TLS2_k127_6904752_1	1163408.UU9_09522	9.947e-130	434.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM ATPase associated with various cellular activities	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
TLS2_k127_6904752_2	1439940.BAY1663_01125	3.569e-117	391.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	PFAM von Willebrand factor type A	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA
TLS2_k127_6916509_3	395495.Lcho_3904	8.039e-76	259.0	COG1522@1|root,COG1522@2|Bacteria,1MXVU@1224|Proteobacteria,2VQ7U@28216|Betaproteobacteria,1KKR2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
TLS2_k127_6916509_0	987059.RBXJA2T_15358	9.702e-114	381.0	COG2199@1|root,COG3706@2|Bacteria,1RD8D@1224|Proteobacteria,2VS5N@28216|Betaproteobacteria,1KNKS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K21019	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
TLS2_k127_6916509_1	987059.RBXJA2T_15363	2.281e-109	364.0	COG0697@1|root,COG0697@2|Bacteria,1MVKG@1224|Proteobacteria,2VM56@28216|Betaproteobacteria,1KJWZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	ko:K15268	-	-	-	-	ko00000,ko02000	2.A.7.3.2	-	-	EamA
TLS2_k127_6916509_4	983917.RGE_02930	9.767e-59	205.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2VSPE@28216|Betaproteobacteria,1KM27@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ApaG domain	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
TLS2_k127_6916509_2	383372.Rcas_3030	6.368e-102	357.0	COG1506@1|root,COG1506@2|Bacteria,2G5NN@200795|Chloroflexi,3765E@32061|Chloroflexia	32061|Chloroflexia	E	peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
TLS2_k127_6928097_2	395493.BegalDRAFT_2875	1.566e-13	77.0	COG4967@1|root,COG4967@2|Bacteria,1NJ3V@1224|Proteobacteria,1SGEX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TLS2_k127_6928097_3	1268237.G114_06035	0.0002601	52.0	2EG5C@1|root,339XA@2|Bacteria,1NQ0T@1224|Proteobacteria,1SIJ6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TLS2_k127_6928097_1	1123377.AUIV01000011_gene2053	7.435e-51	186.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S69B@1236|Gammaproteobacteria,1X7XW@135614|Xanthomonadales	135614|Xanthomonadales	NU	Type II secretion system (T2SS), protein G	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,T2SSG
TLS2_k127_6928097_0	1123377.AUIV01000011_gene2052	6.802e-70	252.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RZ4F@1236|Gammaproteobacteria,1X9DJ@135614|Xanthomonadales	135614|Xanthomonadales	NU	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
TLS2_k127_6941964_0	864051.BurJ1DRAFT_3313	0.0	1593.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria,1KKFR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
TLS2_k127_6941964_1	631362.Thi970DRAFT_00956	2.129e-117	378.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria,1WWTE@135613|Chromatiales	135613|Chromatiales	C	PFAM 4Fe-4S	-	-	-	ko:K00184,ko:K21308	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	5.A.3	-	-	Fer4_11,Fer4_4,Fer4_7
TLS2_k127_6944986_5	365046.Rta_11140	1.151e-11	68.0	COG2002@1|root,COG2002@2|Bacteria,1QVJI@1224|Proteobacteria,2WH1Z@28216|Betaproteobacteria,4AEYD@80864|Comamonadaceae	28216|Betaproteobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
TLS2_k127_6944986_0	358220.C380_00420	1.193e-189	599.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2VH2S@28216|Betaproteobacteria,4A9SH@80864|Comamonadaceae	28216|Betaproteobacteria	C	NADH flavin oxidoreductase NADH oxidase	nemA	GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
TLS2_k127_6944986_4	864051.BurJ1DRAFT_0683	7.994e-35	141.0	COG3094@1|root,COG3094@2|Bacteria,1NPTP@1224|Proteobacteria,2VWBN@28216|Betaproteobacteria,1KMPT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Invasion gene expression up-regulator, SirB	-	-	-	-	-	-	-	-	-	-	-	-	SirB
TLS2_k127_6944986_3	375286.mma_3498	1.834e-36	149.0	COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,2VW5P@28216|Betaproteobacteria,4755N@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF454)	ybaN	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
TLS2_k127_6944986_2	887062.HGR_10680	3.338e-60	218.0	2CJ6B@1|root,32S9B@2|Bacteria,1N2I4@1224|Proteobacteria,2VV7N@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Thermostable hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	T_hemolysin
TLS2_k127_6944986_1	420662.Mpe_A2668	2.219e-146	485.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VN53@28216|Betaproteobacteria,1KNDN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
TLS2_k127_6953421_4	864051.BurJ1DRAFT_2530	1.186e-143	462.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria,1KK6U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
TLS2_k127_6953421_9	864051.BurJ1DRAFT_2528	4.085e-73	255.0	COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,2VJ2N@28216|Betaproteobacteria,1KKM7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Polyhydroxyalkanoate synthesis repressor	phaR	-	-	-	-	-	-	-	-	-	-	-	PHB_acc,PHB_acc_N
TLS2_k127_6953421_8	987059.RBXJA2T_11917	6.776e-92	309.0	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,2VJWH@28216|Betaproteobacteria	28216|Betaproteobacteria	P	3'(2'),5'-bisphosphate nucleotidase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
TLS2_k127_6953421_0	983917.RGE_21830	0.0	1611.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2W18C@28216|Betaproteobacteria,1KP96@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS2_k127_6953421_5	983917.RGE_21840	2.842e-142	463.0	COG0845@1|root,COG0845@2|Bacteria,1PMFM@1224|Proteobacteria,2W1RX@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
TLS2_k127_6953421_3	987059.RBXJA2T_03161	1.154e-151	495.0	COG4177@1|root,COG4177@2|Bacteria,1MWP3@1224|Proteobacteria,2VJA3@28216|Betaproteobacteria,1KJ4J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
TLS2_k127_6953421_2	983917.RGE_02990	7.363e-156	495.0	COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,2VIR5@28216|Betaproteobacteria,1KK90@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
TLS2_k127_6953421_1	983917.RGE_03000	3.849e-224	699.0	COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,2VHXC@28216|Betaproteobacteria,1KJ8V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TLS2_k127_6953421_7	614083.AWQR01000018_gene1819	7.165e-119	400.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2VJA0@28216|Betaproteobacteria,4ABV2@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
TLS2_k127_6953421_6	614083.AWQR01000018_gene1820	3.238e-127	410.0	COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,2VJN5@28216|Betaproteobacteria,4AACW@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	drrA	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
TLS2_k127_6963306_7	983917.RGE_42660	1.951e-18	87.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,2VXRV@28216|Betaproteobacteria,1KMRT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
TLS2_k127_6963306_3	983917.RGE_42650	2.197e-128	415.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,2VIIG@28216|Betaproteobacteria,1KIT2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	-	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
TLS2_k127_6963306_5	864051.BurJ1DRAFT_4387	2.896e-61	220.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2VR8K@28216|Betaproteobacteria,1KKZP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
TLS2_k127_6963306_2	987059.RBXJA2T_11578	2.097e-146	470.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,2VI08@28216|Betaproteobacteria,1KIZ0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
TLS2_k127_6963306_1	983917.RGE_42620	6.11e-220	687.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria,1KJSN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
TLS2_k127_6963306_0	983917.RGE_42610	1.736e-318	981.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,1KJB3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	TIGRFAM type IV-A pilus assembly ATPase PilB	pilB	-	-	ko:K02454,ko:K02504,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
TLS2_k127_6963306_9	768066.HELO_2603	0.0001525	47.0	COG1196@1|root,COG1196@2|Bacteria,1NKHN@1224|Proteobacteria,1SHRR@1236|Gammaproteobacteria,1XMJW@135619|Oceanospirillales	135619|Oceanospirillales	D	Plasmid replication region DNA-binding N-term	-	-	-	-	-	-	-	-	-	-	-	-	KfrA_N
TLS2_k127_6963306_8	640081.Dsui_1482	1.975e-07	59.0	COG4680@1|root,COG4680@2|Bacteria,1N036@1224|Proteobacteria,2VSXP@28216|Betaproteobacteria,2KZGE@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
TLS2_k127_6963306_4	640081.Dsui_1483	3.759e-111	375.0	COG2856@1|root,COG5499@1|root,COG2856@2|Bacteria,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,2VRK1@28216|Betaproteobacteria,2KXA3@206389|Rhodocyclales	206389|Rhodocyclales	K	regulator	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
TLS2_k127_6984136_2	983917.RGE_13610	9.211e-23	111.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria,1KK53@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
TLS2_k127_6984136_0	987059.RBXJA2T_05498	1.372e-153	490.0	COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,2VJTZ@28216|Betaproteobacteria,1KIT3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	transcriptional regulator	allS_2	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS2_k127_6984136_1	420662.Mpe_A2889	4.956e-111	364.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2VHPA@28216|Betaproteobacteria,1KJM5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the pirin family	yhhW_2	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
TLS2_k127_6991409_9	987059.RBXJA2T_01135	1.534e-51	183.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,1KKYS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
TLS2_k127_6991409_6	983917.RGE_08080	1.64e-89	300.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,2VQRE@28216|Betaproteobacteria,1KKP3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
TLS2_k127_6991409_4	296591.Bpro_0746	2.829e-134	444.0	COG3203@1|root,COG3203@2|Bacteria,1R775@1224|Proteobacteria,2VNKK@28216|Betaproteobacteria,4AH3B@80864|Comamonadaceae	28216|Betaproteobacteria	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
TLS2_k127_6991409_3	983917.RGE_08130	2.022e-198	628.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,1KJUP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS2_k127_6991409_10	987059.RBXJA2T_01095	7.736e-49	177.0	COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,2VVS3@28216|Betaproteobacteria,1KM3Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the frataxin family	cyaY	-	-	ko:K06202	-	-	-	-	ko00000	-	-	-	Frataxin_Cyay
TLS2_k127_6991409_0	987059.RBXJA2T_01090	0.0	1214.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VHXF@28216|Betaproteobacteria,1KK5W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	penicillin-binding protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
TLS2_k127_6991409_2	983917.RGE_08170	5.379e-210	655.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,2VH6W@28216|Betaproteobacteria,1KJ3J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
TLS2_k127_6991409_7	987059.RBXJA2T_01080	4.273e-79	270.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,2VN9T@28216|Betaproteobacteria,1KJKT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Fimbrial assembly	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
TLS2_k127_6991409_5	987059.RBXJA2T_01075	2.033e-91	307.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,2VH68@28216|Betaproteobacteria,1KKGW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
TLS2_k127_6991409_8	420662.Mpe_A3110	2.024e-69	247.0	COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,2VSVR@28216|Betaproteobacteria,1KKJA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	pilus assembly protein PilP	pilP	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
TLS2_k127_6991409_1	864051.BurJ1DRAFT_1150	0.0	1028.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria,1KJSP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	type II and III secretion system protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
TLS2_k127_6991409_11	29581.BW37_03135	6.021e-19	98.0	COG2373@1|root,COG2373@2|Bacteria,1QUYV@1224|Proteobacteria,2VS7Q@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1
TLS2_k127_7010745_0	1095769.CAHF01000022_gene87	6.292e-149	478.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VK0Q@28216|Betaproteobacteria,472U6@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	tctC	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
TLS2_k127_7010745_1	1095769.CAHF01000022_gene86	2.755e-129	426.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2WGJW@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
TLS2_k127_7023978_3	987059.RBXJA2T_15533	9.743e-45	164.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria,1KJR7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
TLS2_k127_7023978_2	983917.RGE_08730	9.869e-52	190.0	COG3017@1|root,COG3017@2|Bacteria,1N2F2@1224|Proteobacteria,2VUJH@28216|Betaproteobacteria,1KM9Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
TLS2_k127_7023978_0	987059.RBXJA2T_15543	6.682e-199	637.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2VI6C@28216|Betaproteobacteria,1KJG2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
TLS2_k127_7023978_1	987059.RBXJA2T_15548	1.359e-80	273.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2VI10@28216|Betaproteobacteria,1KJ6R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
TLS2_k127_7037987_2	395495.Lcho_1722	4.423e-48	174.0	COG3638@1|root,COG3638@2|Bacteria,1MXYA@1224|Proteobacteria,2VM4F@28216|Betaproteobacteria,1KP95@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
TLS2_k127_7037987_1	395495.Lcho_1721	1.088e-124	407.0	COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,2VMR7@28216|Betaproteobacteria,1KMAP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
TLS2_k127_7037987_0	395495.Lcho_1720	1.397e-126	424.0	COG3639@1|root,COG3639@2|Bacteria,1MW4F@1224|Proteobacteria,2VKCA@28216|Betaproteobacteria,1KMG7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Phosphonate ABC transporter	phnE	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
TLS2_k127_7037987_3	864051.BurJ1DRAFT_4975	9.38e-32	128.0	2E53B@1|root,32ZWF@2|Bacteria,1N7G8@1224|Proteobacteria,2VVPD@28216|Betaproteobacteria,1KMMZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_7037987_4	983917.RGE_14270	1.078e-26	111.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VNB4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA1	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
TLS2_k127_7044081_3	864051.BurJ1DRAFT_1572	5.614e-42	154.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2VR9P@28216|Betaproteobacteria,1KKSD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
TLS2_k127_7044081_5	420662.Mpe_A2940	5.617e-34	138.0	COG4970@1|root,COG4970@2|Bacteria,1N43I@1224|Proteobacteria,2VUQM@28216|Betaproteobacteria,1KMEB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
TLS2_k127_7044081_6	983917.RGE_38990	7.971e-25	111.0	COG4968@1|root,COG4968@2|Bacteria,1QDNY@1224|Proteobacteria,2W8CB@28216|Betaproteobacteria,1KMJ4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
TLS2_k127_7044081_7	264198.Reut_A0400	9.404e-05	53.0	COG4970@1|root,COG4970@2|Bacteria,1NGHS@1224|Proteobacteria,2WCQW@28216|Betaproteobacteria,1K9MD@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	type 4 fimbrial pilin related transmembrane protein	fimT	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
TLS2_k127_7044081_4	983917.RGE_39010	5.025e-37	150.0	COG4795@1|root,COG4795@2|Bacteria,1N6ZJ@1224|Proteobacteria,2VURU@28216|Betaproteobacteria,1KMB4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	General secretion pathway protein	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
TLS2_k127_7044081_2	987059.RBXJA2T_15228	2.9e-72	268.0	COG4726@1|root,COG4726@2|Bacteria,1RKD2@1224|Proteobacteria,2VSTI@28216|Betaproteobacteria,1KM68@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	PilX_N
TLS2_k127_7044081_1	864051.BurJ1DRAFT_1566	1.265e-74	266.0	COG4967@1|root,COG4967@2|Bacteria,1RKWI@1224|Proteobacteria,2VT6F@28216|Betaproteobacteria,1KM55@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
TLS2_k127_7044081_0	983917.RGE_39040	2.989e-110	362.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,1KJU9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
TLS2_k127_7054265_0	365046.Rta_20610	1.142e-115	375.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,2VJ9A@28216|Betaproteobacteria,4A9VA@80864|Comamonadaceae	28216|Betaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
TLS2_k127_7054265_1	420662.Mpe_A0299	3.654e-75	267.0	COG3240@1|root,COG3240@2|Bacteria,1MYGD@1224|Proteobacteria,2VSIV@28216|Betaproteobacteria,1KM96@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
TLS2_k127_7104963_4	543728.Vapar_1010	9.139e-58	203.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2VNZH@28216|Betaproteobacteria,4AC1K@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Dehydrogenase, E1 component	bkdA1	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,OxoDH_E1alpha_N
TLS2_k127_7104963_0	296591.Bpro_0274	5.177e-197	619.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2VKQ0@28216|Betaproteobacteria,4ACZ7@80864|Comamonadaceae	28216|Betaproteobacteria	C	Transketolase, C-terminal domain	bkdA2	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
TLS2_k127_7104963_1	296591.Bpro_0275	6.489e-158	520.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VKC1@28216|Betaproteobacteria,4ABYH@80864|Comamonadaceae	28216|Betaproteobacteria	C	e3 binding domain	bkdB	-	2.3.1.168	ko:K09699	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R02662,R03174,R04097,R10998	RC00004,RC02727,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS2_k127_7104963_2	987059.RBXJA2T_05183	1.962e-82	276.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2VHJI@28216|Betaproteobacteria,1KK3I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
TLS2_k127_7104963_3	1397284.AYMN01000002_gene2316	2.153e-82	279.0	COG2313@1|root,COG2313@2|Bacteria,1MUQU@1224|Proteobacteria,1RQJH@1236|Gammaproteobacteria,4033R@613|Serratia	1236|Gammaproteobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	GO:0001522,GO:0003674,GO:0003824,GO:0004730,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016043,GO:0016070,GO:0016787,GO:0016798,GO:0016829,GO:0016835,GO:0016836,GO:0022607,GO:0030145,GO:0034641,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0090304,GO:1901360	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
TLS2_k127_7116995_1	987059.RBXJA2T_12652	2.128e-40	151.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2VU1D@28216|Betaproteobacteria,1KMB5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
TLS2_k127_7116995_0	864051.BurJ1DRAFT_3614	2.911e-214	673.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2VI1P@28216|Betaproteobacteria,1KJ8C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
TLS2_k127_7121937_0	935863.AWZR01000003_gene2775	2.233e-168	542.0	COG5368@1|root,COG5368@2|Bacteria,1NX2K@1224|Proteobacteria,1RY8M@1236|Gammaproteobacteria,1X3JA@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
TLS2_k127_7121937_1	215803.DB30_8575	2.589e-65	227.0	COG1653@1|root,COG1653@2|Bacteria,1MX59@1224|Proteobacteria	1224|Proteobacteria	G	ABC transporter substrate-binding protein	malE	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
TLS2_k127_7124427_1	864051.BurJ1DRAFT_2530	3.044e-124	399.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria,1KK6U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
TLS2_k127_7124427_0	983917.RGE_31040	1.005e-176	561.0	COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,2VHNW@28216|Betaproteobacteria,1KJ3A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metC	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
TLS2_k127_7124427_2	987059.RBXJA2T_14716	1.436e-77	261.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2VRG9@28216|Betaproteobacteria,1KKJN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
TLS2_k127_7124427_3	987059.RBXJA2T_14711	6.127e-58	206.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2VR4X@28216|Betaproteobacteria,1KKXZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	cyclase dehydrase	ratA	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
TLS2_k127_712582_0	1454004.AW11_02462	7.657e-131	425.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,2VI22@28216|Betaproteobacteria,1KR09@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	PT	CPA1 family monovalent cation H antiporter	nhaK	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,cNMP_binding
TLS2_k127_712582_2	987059.RBXJA2T_07160	1.072e-43	172.0	COG0589@1|root,COG0589@2|Bacteria,1N674@1224|Proteobacteria,2VTHJ@28216|Betaproteobacteria,1KMM1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS2_k127_712582_1	999541.bgla_2g05820	1.025e-91	308.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VS4U@28216|Betaproteobacteria,1K6P9@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Amidase	pam	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
TLS2_k127_7145254_0	358220.C380_12755	0.0	1019.0	COG2216@1|root,COG2216@2|Bacteria,1MU7D@1224|Proteobacteria,2VH26@28216|Betaproteobacteria,4ABWT@80864|Comamonadaceae	28216|Betaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
TLS2_k127_7145254_1	358220.C380_12750	6.081e-284	886.0	COG2060@1|root,COG2060@2|Bacteria,1MV1K@1224|Proteobacteria,2VI68@28216|Betaproteobacteria,4ACPU@80864|Comamonadaceae	28216|Betaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
TLS2_k127_7145254_5	543728.Vapar_4530	2.74e-53	201.0	2F1SA@1|root,33USF@2|Bacteria,1NVHZ@1224|Proteobacteria,2W20M@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_7145254_7	1434929.X946_4045	7.655e-26	110.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,2VJIT@28216|Betaproteobacteria,1K3QJ@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS2_k127_7145254_6	987059.RBXJA2T_08575	2.809e-38	145.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2VJHD@28216|Betaproteobacteria,1KK1M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS2_k127_7145254_4	420662.Mpe_A1890	9.559e-71	241.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2VJHD@28216|Betaproteobacteria,1KK1M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS2_k127_7145254_8	267608.RSp0203	1.361e-19	102.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,2VQ4Q@28216|Betaproteobacteria,1K45W@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Thioesterase superfamily protein	-	-	3.1.2.20	ko:K01073	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
TLS2_k127_7145254_3	987059.RBXJA2T_14246	1.681e-202	635.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2VH0S@28216|Betaproteobacteria,1KJ9W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
TLS2_k127_7145254_2	983917.RGE_09580	2.698e-236	734.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria,1KJVQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
TLS2_k127_7157476_1	887062.HGR_15854	3.844e-18	84.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,4A9JM@80864|Comamonadaceae	28216|Betaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
TLS2_k127_7157476_0	420662.Mpe_A2756	4.357e-146	467.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,2VHB2@28216|Betaproteobacteria,1KJWE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	phosphoesterase, PHP	-	GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
TLS2_k127_7157476_2	1122619.KB892324_gene49	1.279e-12	74.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,3T2KW@506|Alcaligenaceae	28216|Betaproteobacteria	JKL	Belongs to the DEAD box helicase family	rhlE1	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
TLS2_k127_7157738_2	987059.RBXJA2T_00170	2e-115	392.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria,1KJM4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Amidohydrolase family	pyrX	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
TLS2_k127_7157738_1	983917.RGE_42000	2.589e-189	593.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2VHG9@28216|Betaproteobacteria,1KIWV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
TLS2_k127_7157738_4	983917.RGE_42010	2.162e-74	253.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,2VSNM@28216|Betaproteobacteria,1KKY6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
TLS2_k127_7157738_6	1265502.KB905941_gene2901	2.338e-56	201.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2VUH0@28216|Betaproteobacteria,4AE0V@80864|Comamonadaceae	28216|Betaproteobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yqgF	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
TLS2_k127_7157738_3	983917.RGE_42030	2.828e-99	326.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,1KJDQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	algH	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
TLS2_k127_7157738_0	987059.RBXJA2T_00195	4.555e-244	763.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2VITS@28216|Betaproteobacteria,1KIUG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	DNA photolyase	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
TLS2_k127_7157738_5	338969.Rfer_1673	3.029e-60	211.0	COG2199@1|root,COG3706@2|Bacteria,1R6GI@1224|Proteobacteria,2VM5N@28216|Betaproteobacteria,4A9XC@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
TLS2_k127_7179033_4	404589.Anae109_3084	3.934e-22	99.0	2C6TZ@1|root,32RHS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_7179033_0	589924.Ferp_0646	7.989e-103	347.0	COG5557@1|root,arCOG02025@2157|Archaea,2XWFI@28890|Euryarchaeota	28890|Euryarchaeota	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
TLS2_k127_7179033_1	1379698.RBG1_1C00001G0296	4.004e-69	258.0	COG0437@1|root,COG0437@2|Bacteria,2NR78@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S binding domain	ttrB	-	-	ko:K08358	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Fer4_11,Fer4_3,Fer4_7
TLS2_k127_7179033_5	247639.MGP2080_12529	7.2e-22	109.0	COG2863@1|root,COG2863@2|Bacteria,1RGTS@1224|Proteobacteria,1S6MS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2863 Cytochrome c553	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
TLS2_k127_7179033_3	404589.Anae109_3087	1.391e-25	120.0	2EE9W@1|root,3384B@2|Bacteria,1NCE1@1224|Proteobacteria,42VUH@68525|delta/epsilon subdivisions,2WSA1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit	cbcS	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Paired_CXXCH_1
TLS2_k127_7179033_2	880073.Calab_1598	3.464e-61	217.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria	2|Bacteria	P	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
TLS2_k127_7180384_3	983917.RGE_09380	1.01e-07	54.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VJXE@28216|Betaproteobacteria,1KM18@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
TLS2_k127_7180384_0	987059.RBXJA2T_14346	6.233e-146	466.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,1KJGC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
TLS2_k127_7180384_2	388051.AUFE01000006_gene1255	2.14e-08	60.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2VIMU@28216|Betaproteobacteria,1JZUC@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
TLS2_k127_7180384_1	1196835.A458_02285	5.33e-23	98.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1YZRQ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	iJN746.PP_4935,iPC815.YPO1395,iUMN146_1321.UM146_12980	ABC_membrane,ABC_tran
TLS2_k127_7190391_0	864051.BurJ1DRAFT_0229	9.302e-311	964.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2VIV3@28216|Betaproteobacteria,1KIZE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
TLS2_k127_7190391_1	1297617.JPJD01000021_gene1466	1.599e-26	110.0	COG2313@1|root,COG2313@2|Bacteria,1TR5J@1239|Firmicutes,247J8@186801|Clostridia,26852@186813|unclassified Clostridiales	186801|Clostridia	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
TLS2_k127_7214782_2	420662.Mpe_A0638	4.359e-94	311.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,1KJXH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	reductase	fabG	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS2_k127_7214782_4	987059.RBXJA2T_06420	5.646e-39	146.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,1KMBB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TLS2_k127_7214782_0	983917.RGE_41090	2.191e-236	735.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria,1KJ46@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817	2.3.1.179	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS2_k127_7214782_1	983917.RGE_41070	5.362e-99	325.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,1KK2V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS2_k127_7214782_3	987059.RBXJA2T_06400	5.847e-46	173.0	COG3073@1|root,COG3073@2|Bacteria,1N3E9@1224|Proteobacteria,2VUN0@28216|Betaproteobacteria,1KMA2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	PFAM Anti sigma-E protein RseA	-	-	-	ko:K03597	-	-	-	-	ko00000,ko03021	-	-	-	RseA_N
TLS2_k127_724029_0	987059.RBXJA2T_12627	4.119e-287	893.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria,1KJ1Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
TLS2_k127_724029_1	864051.BurJ1DRAFT_3623	1.475e-67	229.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2VSQE@28216|Betaproteobacteria,1KM0Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Ferredoxin, 2Fe-2S type, ISC system	fdx	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
TLS2_k127_724029_2	864051.BurJ1DRAFT_3748	2.292e-14	72.0	COG0406@1|root,COG0406@2|Bacteria,1RB0S@1224|Proteobacteria,2VJR8@28216|Betaproteobacteria,1KMNR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
TLS2_k127_7257669_0	748247.AZKH_3430	4.059e-166	533.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,2VIT3@28216|Betaproteobacteria,2KUC5@206389|Rhodocyclales	206389|Rhodocyclales	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
TLS2_k127_7257669_4	748247.AZKH_3429	4.372e-64	224.0	COG3437@1|root,COG3437@2|Bacteria,1RDJ3@1224|Proteobacteria,2VR5G@28216|Betaproteobacteria,2KWE0@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS2_k127_7257669_3	748247.AZKH_3428	1.019e-87	295.0	COG1100@1|root,COG1100@2|Bacteria,1RCJJ@1224|Proteobacteria,2VIVX@28216|Betaproteobacteria,2KY1T@206389|Rhodocyclales	206389|Rhodocyclales	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
TLS2_k127_7257669_2	748247.AZKH_3427	1.249e-98	347.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VPGG@28216|Betaproteobacteria,2KYCK@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS2_k127_7257669_1	748247.AZKH_3426	5.341e-125	409.0	COG2804@1|root,COG3437@1|root,COG2804@2|Bacteria,COG3437@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KVIS@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Response_reg,T2SSE,T2SSE_N
TLS2_k127_7257962_0	1265502.KB905951_gene843	5.987e-142	454.0	COG1116@1|root,COG1116@2|Bacteria,1N7FP@1224|Proteobacteria,2VHGX@28216|Betaproteobacteria,4ACTB@80864|Comamonadaceae	28216|Betaproteobacteria	P	SMART AAA ATPase	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
TLS2_k127_7257962_1	1265502.KB905951_gene842	9.386e-138	445.0	COG0600@1|root,COG0600@2|Bacteria,1MVD2@1224|Proteobacteria,2VI9N@28216|Betaproteobacteria,4AC9H@80864|Comamonadaceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
TLS2_k127_7257962_2	395495.Lcho_2111	3.485e-37	144.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,2VK2V@28216|Betaproteobacteria,1KK57@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
TLS2_k127_7267404_0	987059.RBXJA2T_05163	1.002e-243	760.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2VIZ7@28216|Betaproteobacteria,1KKAP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.2,1.4.1.3	ko:K00260,ko:K00261	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
TLS2_k127_7273086_1	987059.RBXJA2T_14926	1.931e-154	520.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2VJTH@28216|Betaproteobacteria,1KJQ7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	mechanosensitive ion channel	aefA	-	-	-	-	-	-	-	-	-	-	-	MS_channel
TLS2_k127_7273086_0	983917.RGE_34570	1.141e-159	516.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VIK8@28216|Betaproteobacteria,1KJ7N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	BQ	histone deacetylase	hdaH	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
TLS2_k127_7273086_2	987059.RBXJA2T_14936	2.048e-91	302.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,1KJ4M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	associated with various cellular activities	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS2_k127_7285269_2	883126.HMPREF9710_00911	2.218e-63	226.0	COG2173@1|root,COG2173@2|Bacteria,1RENK@1224|Proteobacteria,2WFWZ@28216|Betaproteobacteria,478U7@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
TLS2_k127_7285269_0	395495.Lcho_3694	1.114e-203	644.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,1MVZ0@1224|Proteobacteria,2VKEY@28216|Betaproteobacteria,1KN85@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Nucleoside recognition	spmAB	-	-	-	-	-	-	-	-	-	-	-	Gate
TLS2_k127_7285269_1	983917.RGE_46750	4.226e-127	413.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,2VHTB@28216|Betaproteobacteria,1KK3K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TLS2_k127_7291742_2	391937.NA2_06807	3.688e-118	394.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,43JD6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
TLS2_k127_7291742_1	391937.NA2_06812	2.748e-122	400.0	COG4120@1|root,COG4120@2|Bacteria,1MXGE@1224|Proteobacteria,2TUWW@28211|Alphaproteobacteria,43GVA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
TLS2_k127_7291742_3	391937.NA2_06817	1.283e-114	389.0	COG1101@1|root,COG1101@2|Bacteria,1MVDM@1224|Proteobacteria,2TTDS@28211|Alphaproteobacteria,43H82@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	transport system ATPase component	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
TLS2_k127_7291742_5	1121381.JNIV01000024_gene1506	4.906e-75	256.0	COG2128@1|root,COG2128@2|Bacteria,1WMUS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
TLS2_k127_7291742_6	76114.ebA3914	1.433e-41	168.0	COG1556@1|root,COG1556@2|Bacteria,1R4TE@1224|Proteobacteria,2VJCF@28216|Betaproteobacteria,2KWJC@206389|Rhodocyclales	206389|Rhodocyclales	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
TLS2_k127_7291742_0	76114.ebA3917	1.483e-203	648.0	COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,2VJ3Y@28216|Betaproteobacteria,2KU8D@206389|Rhodocyclales	206389|Rhodocyclales	C	Domain of unknown function (DUF3390)	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
TLS2_k127_7291742_4	1205680.CAKO01000040_gene593	1.507e-108	355.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2TR9H@28211|Alphaproteobacteria,2JQMV@204441|Rhodospirillales	204441|Rhodospirillales	C	(Fe-S) oxidoreductase	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
TLS2_k127_7292879_2	1123504.JQKD01000013_gene1057	9.704e-84	281.0	COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,2VI0J@28216|Betaproteobacteria,4AAFW@80864|Comamonadaceae	28216|Betaproteobacteria	C	CO dehydrogenase flavoprotein domain protein	xdhA	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
TLS2_k127_7292879_0	983917.RGE_39980	2.612e-212	670.0	COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,2VJN1@28216|Betaproteobacteria,1KJPU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Guanine deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
TLS2_k127_7292879_1	1198452.Jab_1c00180	5.494e-195	659.0	COG2931@1|root,COG4886@1|root,COG2931@2|Bacteria,COG4886@2|Bacteria,1QQDR@1224|Proteobacteria,2VK3B@28216|Betaproteobacteria,4779G@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_7293394_1	420662.Mpe_A0622	1.471e-30	122.0	COG3524@1|root,COG3524@2|Bacteria,1R3ZY@1224|Proteobacteria,2WFDA@28216|Betaproteobacteria,1KMC5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	COG3524 Capsule polysaccharide export protein	kpsE	-	-	ko:K10107	ko02010,map02010	M00249	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.101	-	-	-
TLS2_k127_7293394_0	1265502.KB905974_gene586	5.637e-234	739.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2VJBU@28216|Betaproteobacteria,4AFRQ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Polysaccharide biosynthesis/export protein	kpsD	-	-	-	-	-	-	-	-	-	-	-	Caps_synth_GfcC,Poly_export,SLBB
TLS2_k127_7300842_2	987059.RBXJA2T_12177	2.12e-68	241.0	COG2413@1|root,COG2413@2|Bacteria,1RFTH@1224|Proteobacteria,2VJC9@28216|Betaproteobacteria,1KKRC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_7300842_1	983917.RGE_42220	8.947e-95	316.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2VHW8@28216|Betaproteobacteria,1KJAT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
TLS2_k127_7300842_0	864051.BurJ1DRAFT_4247	3.683e-125	405.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,2VKSW@28216|Betaproteobacteria,1KJAB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
TLS2_k127_7321506_0	987059.RBXJA2T_04138	3.797e-283	877.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VGZE@28216|Betaproteobacteria,1KIY7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	alkK	-	6.2.1.44	ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
TLS2_k127_7321506_1	1005048.CFU_0200	1.077e-259	827.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2VPBK@28216|Betaproteobacteria,476E0@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
TLS2_k127_7321506_2	1123504.JQKD01000007_gene3343	4.53e-132	431.0	COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2VH58@28216|Betaproteobacteria,4AB0M@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TLS2_k127_7325163_2	395495.Lcho_3755	6.848e-118	383.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,1KKER@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp1	-	3.1.3.11,3.1.3.37	ko:K01086,ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R01845,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
TLS2_k127_7325163_1	395495.Lcho_3757	3.407e-160	509.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,1KKHM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
TLS2_k127_7325163_0	395495.Lcho_3767	1.486e-298	917.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria,1KJRD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbM	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
TLS2_k127_7325163_4	864051.BurJ1DRAFT_1182	3.913e-39	158.0	2EGJT@1|root,33ABY@2|Bacteria,1NGI4@1224|Proteobacteria,2VX3Y@28216|Betaproteobacteria,1KMI2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn)	-	-	-	-	-	-	-	-	-	-	-	-	PHA_gran_rgn
TLS2_k127_7325163_3	983917.RGE_08470	4.089e-103	340.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria,1KKFH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
TLS2_k127_734677_1	365046.Rta_25110	4.259e-127	410.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2VIYE@28216|Betaproteobacteria,4AAGA@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Radical SAM domain protein	splB	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS2_k127_734677_4	543728.Vapar_3963	6.725e-17	89.0	2EBGE@1|root,335H0@2|Bacteria,1ND3F@1224|Proteobacteria,2VVY6@28216|Betaproteobacteria,4AFNT@80864|Comamonadaceae	28216|Betaproteobacteria	S	Oxidoreductase-like protein, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored-like
TLS2_k127_734677_3	398578.Daci_5371	4.407e-25	113.0	COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,2VVVS@28216|Betaproteobacteria,4AF6Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
TLS2_k127_734677_2	365044.Pnap_3745	6.438e-102	351.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2VK0C@28216|Betaproteobacteria,4AAKX@80864|Comamonadaceae	28216|Betaproteobacteria	K	response regulator, receiver	dctR	-	-	ko:K11712	ko02020,map02020	-	-	-	ko00000,ko00001,ko02022	-	-	-	GerE,Response_reg
TLS2_k127_734677_0	365044.Pnap_3746	6.864e-137	442.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,4AGGW@80864|Comamonadaceae	28216|Betaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	2.7.13.3	ko:K11711	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
TLS2_k127_7357973_1	864051.BurJ1DRAFT_3941	1.999e-75	263.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,1KJ0A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	COG3170 Tfp pilus assembly protein FimV	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
TLS2_k127_7357973_0	987059.RBXJA2T_00974	3.617e-127	414.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2VI0R@28216|Betaproteobacteria,1KJ1J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
TLS2_k127_7357973_2	987059.RBXJA2T_00969	6.259e-72	248.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria,1KK51@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
TLS2_k127_7360649_2	864051.BurJ1DRAFT_4041	2.464e-59	211.0	COG0457@1|root,COG0457@2|Bacteria,1RAPH@1224|Proteobacteria,2VPDH@28216|Betaproteobacteria,1KMCK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_7360649_0	864051.BurJ1DRAFT_4042	1.084e-147	479.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2VM5U@28216|Betaproteobacteria,1KKXE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
TLS2_k127_7360649_1	983917.RGE_02560	8.007e-83	280.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2VH5F@28216|Betaproteobacteria,1KK56@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
TLS2_k127_7363672_0	983917.RGE_43410	9.327e-177	563.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2VH59@28216|Betaproteobacteria,1KJWT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	carboxylase	accA1	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
TLS2_k127_7363672_1	987059.RBXJA2T_03046	4.307e-156	499.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2VIUW@28216|Betaproteobacteria,1KJ51@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	HMGL-like	hmgcL	GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
TLS2_k127_7363672_3	983917.RGE_43390	3.82e-69	241.0	COG2606@1|root,COG2606@2|Bacteria,1RD82@1224|Proteobacteria,2VQJW@28216|Betaproteobacteria,1KKV3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	YbaK prolyl-tRNA synthetase associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1289,tRNA_edit
TLS2_k127_7363672_4	864051.BurJ1DRAFT_4735	3.105e-15	81.0	COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,2VXYJ@28216|Betaproteobacteria,1KMVN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1289)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
TLS2_k127_7363672_2	1504672.669784317	1.03e-75	264.0	COG3917@1|root,COG3917@2|Bacteria,1RJFB@1224|Proteobacteria,2VPYN@28216|Betaproteobacteria,4ACDE@80864|Comamonadaceae	28216|Betaproteobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
TLS2_k127_7369259_3	864051.BurJ1DRAFT_3327	6.196e-106	346.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,1KKEG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADPH-dependent glutamate synthase beta	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_21,Fer4_7,Pyr_redox_2,Pyr_redox_3
TLS2_k127_7369259_1	864051.BurJ1DRAFT_3328	2.811e-243	756.0	COG0446@1|root,COG0446@2|Bacteria,1QSG7@1224|Proteobacteria,2W9DB@28216|Betaproteobacteria,1KKDR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS2_k127_7369259_0	864051.BurJ1DRAFT_3329	9.607e-286	884.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,2VJGA@28216|Betaproteobacteria,1KN5P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Fe-S oxidoreductase	-	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
TLS2_k127_7369259_2	864051.BurJ1DRAFT_3330	5.25e-119	388.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,2VPFB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
TLS2_k127_7369259_4	864051.BurJ1DRAFT_3331	2.807e-63	220.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,2VSFJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
TLS2_k127_7369259_5	1123393.KB891316_gene1847	1.46e-10	62.0	COG2168@1|root,COG2168@2|Bacteria,1PTT8@1224|Proteobacteria,2VWF4@28216|Betaproteobacteria,1KT55@119069|Hydrogenophilales	119069|Hydrogenophilales	P	DsrH like protein	-	-	-	ko:K07237	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DsrH
TLS2_k127_7373251_2	987059.RBXJA2T_15753	1.546e-132	425.0	COG0765@1|root,COG0765@2|Bacteria,1MUVX@1224|Proteobacteria,2VJ8A@28216|Betaproteobacteria,1KK9S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	gltJ	-	-	ko:K02029,ko:K10003	ko02010,ko02020,map02010,map02020	M00230,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
TLS2_k127_7373251_3	397945.Aave_4071	1.637e-94	314.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2VIQB@28216|Betaproteobacteria,4AAVP@80864|Comamonadaceae	28216|Betaproteobacteria	P	polar amino acid ABC transporter, inner membrane subunit	gltK	-	-	ko:K10002	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
TLS2_k127_7373251_1	395495.Lcho_2685	3.995e-137	443.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2VHIC@28216|Betaproteobacteria,1KKCD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	PFAM ABC transporter	gltL	-	-	ko:K09972,ko:K10004	ko02010,ko02020,map02010,map02020	M00230,M00232	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.17,3.A.1.3.18,3.A.1.3.19,3.A.1.3.4,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
TLS2_k127_7373251_0	983917.RGE_09370	2.151e-174	552.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,1KJF0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
TLS2_k127_7373251_4	983917.RGE_09380	1.428e-61	222.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VJXE@28216|Betaproteobacteria,1KM18@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
TLS2_k127_7383414_0	864051.BurJ1DRAFT_4494	7.352e-177	563.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2VHC6@28216|Betaproteobacteria,1KJ96@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
TLS2_k127_7383414_2	420662.Mpe_A0307	2.437e-63	220.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2VR5Y@28216|Betaproteobacteria,1KKV6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
TLS2_k127_7383414_1	987059.RBXJA2T_16262	3.334e-79	278.0	COG5652@1|root,COG5652@2|Bacteria,1PJUW@1224|Proteobacteria,2VHEZ@28216|Betaproteobacteria,1KJNI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
TLS2_k127_7384682_3	987059.RBXJA2T_15268	2.992e-16	79.0	COG0745@1|root,COG0745@2|Bacteria,1RJB3@1224|Proteobacteria,2VRB3@28216|Betaproteobacteria,1KKXC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	response regulator	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
TLS2_k127_7384682_1	983917.RGE_17400	6.113e-129	437.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2VQJ3@28216|Betaproteobacteria,1KJC2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
TLS2_k127_7384682_2	987059.RBXJA2T_01215	1.702e-17	89.0	COG2198@1|root,COG2198@2|Bacteria,1NBYP@1224|Proteobacteria,2VXSP@28216|Betaproteobacteria,1KP2U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
TLS2_k127_7384682_0	420662.Mpe_A2857	0.0	1090.0	COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KK2Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,Response_reg
TLS2_k127_7386291_1	543728.Vapar_4487	3.831e-201	629.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2VHRD@28216|Betaproteobacteria,4ABWV@80864|Comamonadaceae	28216|Betaproteobacteria	EH	Belongs to the TPP enzyme family	oxc	-	4.1.1.8	ko:K01577	ko00630,ko01100,map00630,map01100	-	R01908	RC00620	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TLS2_k127_7386291_0	391038.Bphy_3617	3.295e-243	754.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHYG@28216|Betaproteobacteria,1KGIR@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate	frc	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
TLS2_k127_7395791_2	987059.RBXJA2T_17841	5.084e-62	226.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,1KJ33@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
TLS2_k127_7395791_1	987059.RBXJA2T_17836	8.619e-100	330.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2VI65@28216|Betaproteobacteria,1KJJ1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Glutathione S-transferase	gst8	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_C_3,GST_C_4,GST_N_3
TLS2_k127_7395791_0	983917.RGE_04900	3.284e-123	407.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2VIBZ@28216|Betaproteobacteria,1KJ0U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
TLS2_k127_7395791_3	983917.RGE_04910	7.038e-32	126.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria,1KJ7Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Lytic transglycosylase catalytic	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
TLS2_k127_7397539_0	420662.Mpe_A0491	5.634e-240	747.0	COG1028@1|root,COG3320@1|root,COG1028@2|Bacteria,COG3320@2|Bacteria,1QSHC@1224|Proteobacteria,2VKRX@28216|Betaproteobacteria,1KMYT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4,adh_short
TLS2_k127_7397539_1	983917.RGE_10270	2.316e-51	189.0	COG3937@1|root,COG3937@2|Bacteria,1RIXG@1224|Proteobacteria,2VT1J@28216|Betaproteobacteria,1KM36@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Poly(hydroxyalcanoate) granule associated protein (phasin)	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
TLS2_k127_7411624_0	365046.Rta_05320	2.215e-75	260.0	COG0406@1|root,COG0406@2|Bacteria,1RB0S@1224|Proteobacteria,2VJR8@28216|Betaproteobacteria,4AABW@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
TLS2_k127_7411624_2	420662.Mpe_A0248	6.112e-29	120.0	2EGTE@1|root,33AJI@2|Bacteria,1N5DW@1224|Proteobacteria,2VUCZ@28216|Betaproteobacteria,1KMN4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
TLS2_k127_7411624_1	420662.Mpe_A0247	2.546e-38	149.0	COG1379@1|root,COG1379@2|Bacteria,1MVED@1224|Proteobacteria,2VJM0@28216|Betaproteobacteria,1KJW4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
TLS2_k127_7423128_1	420662.Mpe_A0290	2.282e-230	720.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2VHN5@28216|Betaproteobacteria,1KK7K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Belongs to the pyruvate kinase family	pykA	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
TLS2_k127_7423128_3	1184609.KILIM_030_00120	6.673e-17	83.0	2DSMH@1|root,33GPM@2|Bacteria,2GR8G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_7423128_2	1123023.JIAI01000008_gene1486	1.404e-31	128.0	COG1848@1|root,COG1848@2|Bacteria,2IJ89@201174|Actinobacteria,4EBUF@85010|Pseudonocardiales	201174|Actinobacteria	S	PIN domain	-	GO:0005575,GO:0005576	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
TLS2_k127_7423128_0	395495.Lcho_0359	0.0	1219.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,1KJ6F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
TLS2_k127_7433246_0	987059.RBXJA2T_05143	0.0	1434.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2VITK@28216|Betaproteobacteria,1KJ8X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.3.8.7,1.5.5.2	ko:K00249,ko:K00294,ko:K13821	ko00071,ko00250,ko00280,ko00330,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00250,map00280,map00330,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00245,R00707,R00708,R00924,R01175,R01253,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04444,R04445,R04751,R04754,R05051	RC00052,RC00068,RC00076,RC00080,RC00083,RC00095,RC00148,RC00216,RC00242,RC00246,RC00255	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
TLS2_k127_7433246_1	983917.RGE_00840	5.774e-107	351.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria,1KKF3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
TLS2_k127_7439968_4	575540.Isop_0323	1.074e-51	187.0	COG2730@1|root,COG2730@2|Bacteria,2J24N@203682|Planctomycetes	203682|Planctomycetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
TLS2_k127_7439968_0	1123487.KB892844_gene822	6.609e-191	604.0	COG1653@1|root,COG1653@2|Bacteria,1PCRV@1224|Proteobacteria,2VN28@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
TLS2_k127_7439968_1	1123487.KB892844_gene821	5.263e-141	457.0	COG1175@1|root,COG1175@2|Bacteria,1R854@1224|Proteobacteria,2VMNW@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
TLS2_k127_7439968_2	1123487.KB892843_gene818	4.242e-132	442.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,2WEEU@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K05815,ko:K17246	ko02010,map02010	M00198,M00207,M00601	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3,3.A.1.1.40	-	-	BPD_transp_1
TLS2_k127_7439968_3	1502852.FG94_05117	1.382e-115	377.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,2VIBY@28216|Betaproteobacteria,476RH@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Glycosyl hydrolase family 1	bglA2	-	3.2.1.21,3.2.1.86	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	-	R00026,R00839,R02558,R02887,R02985,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
TLS2_k127_7448193_0	187303.BN69_2480	1.332e-263	833.0	COG0463@1|root,COG4641@1|root,COG0463@2|Bacteria,COG4641@2|Bacteria,1QWS1@1224|Proteobacteria,2TX3C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase family 2	-	-	2.7.8.20	ko:K01002	ko01100,map01100	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
TLS2_k127_7448193_1	1033739.CAEU01000011_gene2551	3.984e-11	75.0	COG1506@1|root,COG1506@2|Bacteria,1VD78@1239|Firmicutes,4HNE1@91061|Bacilli,26FRV@186818|Planococcaceae	91061|Bacilli	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
TLS2_k127_7454453_1	864051.BurJ1DRAFT_2989	7.268e-133	424.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,1KJ1K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
TLS2_k127_7454453_0	987059.RBXJA2T_19126	0.0	1425.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,1KK9N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
TLS2_k127_7461130_0	290397.Adeh_0008	1.082e-93	325.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42MIV@68525|delta/epsilon subdivisions,2WJ5X@28221|Deltaproteobacteria,2YUAI@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
TLS2_k127_7461130_2	365044.Pnap_0116	3.355e-05	52.0	COG0664@1|root,COG0664@2|Bacteria,1N437@1224|Proteobacteria,2VU5S@28216|Betaproteobacteria,4AF2J@80864|Comamonadaceae	28216|Betaproteobacteria	T	Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
TLS2_k127_7461130_1	987059.RBXJA2T_09397	9.327e-56	205.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2VQZR@28216|Betaproteobacteria,1KPHX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
TLS2_k127_765586_2	987059.RBXJA2T_11186	3.505e-168	533.0	COG0189@1|root,COG0189@2|Bacteria,1QVU3@1224|Proteobacteria,2WH5E@28216|Betaproteobacteria,1KIV9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	HJ	Glutamate-cysteine ligase	-	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GshA
TLS2_k127_765586_0	420662.Mpe_A0174	2.03e-322	997.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria,1KJ7D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
TLS2_k127_765586_1	864051.BurJ1DRAFT_0281	1.237e-188	593.0	COG0646@1|root,COG0646@2|Bacteria,1NPFY@1224|Proteobacteria,2VJ2K@28216|Betaproteobacteria,1KJQA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	homocysteine S-methyltransferase	metHa	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
TLS2_k127_765586_3	864051.BurJ1DRAFT_1260	1.196e-129	432.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KKDK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	gmr	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,MHYT
TLS2_k127_765586_4	983917.RGE_02060	4.232e-41	159.0	2DN7F@1|root,32VYA@2|Bacteria,1QUZI@1224|Proteobacteria,2VUAZ@28216|Betaproteobacteria,1KMCG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
TLS2_k127_780759_6	543728.Vapar_3817	3.558e-93	313.0	COG2188@1|root,COG2188@2|Bacteria,1R790@1224|Proteobacteria,2VKB7@28216|Betaproteobacteria,4AGM9@80864|Comamonadaceae	28216|Betaproteobacteria	K	UTRA domain	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
TLS2_k127_780759_7	543728.Vapar_3818	2.126e-46	169.0	COG2721@1|root,COG2721@2|Bacteria,1MZBN@1224|Proteobacteria,2VU0R@28216|Betaproteobacteria,4AI5A@80864|Comamonadaceae	28216|Betaproteobacteria	G	SAF	-	-	4.4.1.24	ko:K16845	ko00270,map00270	-	R07633	RC01785	ko00000,ko00001,ko01000	-	-	-	SAF
TLS2_k127_780759_0	543728.Vapar_3819	1.054e-230	718.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2VK3Y@28216|Betaproteobacteria,4AGID@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM D-galactarate dehydratase Altronate hydrolase domain protein	-	-	4.4.1.24	ko:K16846	ko00270,map00270	-	R07633	RC01785	ko00000,ko00001,ko01000	-	-	-	GD_AH_C
TLS2_k127_780759_5	1120983.KB894571_gene2250	2.639e-113	377.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,1JPZ9@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
TLS2_k127_780759_1	1089551.KE386572_gene917	2.763e-205	649.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,4BRAF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA,TctB
TLS2_k127_780759_8	290398.Csal_1769	3.428e-11	74.0	COG3333@1|root,COG3333@2|Bacteria,1N7DF@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
TLS2_k127_780759_3	543728.Vapar_3820	4.062e-126	417.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2VJ2T@28216|Betaproteobacteria,4AH60@80864|Comamonadaceae	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	serA2	-	1.1.1.310,1.1.1.399,1.1.1.95	ko:K00058,ko:K16843	ko00260,ko00270,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513,R05693	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TLS2_k127_780759_2	543728.Vapar_3821	4.247e-143	480.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2VIZR@28216|Betaproteobacteria,4ACBY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	1.1.1.338,1.5.1.21	ko:K13609,ko:K16844	ko00270,ko00310,ko00960,ko01100,ko01120,map00270,map00310,map00960,map01100,map01120	-	R02203,R07137	RC00031,RC00135	ko00000,ko00001,ko01000	-	-	-	Ldh_2
TLS2_k127_780759_4	595537.Varpa_4402	1.286e-121	415.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,2VHRC@28216|Betaproteobacteria,4AAT8@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
TLS2_k127_81007_0	1458275.AZ34_02940	4.176e-152	486.0	COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,2VJN1@28216|Betaproteobacteria,4AAMZ@80864|Comamonadaceae	28216|Betaproteobacteria	F	Guanine deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
TLS2_k127_81007_1	887062.HGR_05166	5.994e-131	421.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,2VH5W@28216|Betaproteobacteria,4AAKP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Basic membrane lipoprotein	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
TLS2_k127_83739_2	983917.RGE_04690	4.46e-38	144.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2VI6V@28216|Betaproteobacteria,1KKFW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
TLS2_k127_83739_0	987059.RBXJA2T_06295	2.462e-114	382.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,1KIY9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	rimN	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
TLS2_k127_83739_1	987059.RBXJA2T_06300	1.008e-84	301.0	COG3240@1|root,COG3240@2|Bacteria,1RI6H@1224|Proteobacteria,2VTGG@28216|Betaproteobacteria,1KM0N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	lipase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_83739_3	987059.RBXJA2T_06315	9.591e-29	118.0	COG4095@1|root,COG4095@2|Bacteria,1N759@1224|Proteobacteria,2VVPU@28216|Betaproteobacteria,1KMHU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PQ loop repeat	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	PQ-loop
TLS2_k127_83739_4	983917.RGE_04760	1.412e-11	66.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2VQR7@28216|Betaproteobacteria,1KM57@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Peptidase M22, glycoprotease	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
TLS2_k127_837905_1	983917.RGE_45540	3.726e-151	485.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,2WGJY@28216|Betaproteobacteria,1KKHB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
TLS2_k127_837905_0	983917.RGE_45550	4.136e-161	525.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,2VHH7@28216|Betaproteobacteria,1KJEK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
TLS2_k127_837905_2	983917.RGE_45560	7.353e-151	484.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,2VJY4@28216|Betaproteobacteria,1KKFM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
TLS2_k127_837905_3	316274.Haur_2448	1.24e-66	246.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
TLS2_k127_837905_4	983917.RGE_45570	4.019e-28	117.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,2VX20@28216|Betaproteobacteria	28216|Betaproteobacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
TLS2_k127_845937_1	1354722.JQLS01000008_gene2579	2.074e-48	178.0	COG1999@1|root,COG1999@2|Bacteria,1N19Q@1224|Proteobacteria,2VFD4@28211|Alphaproteobacteria,46PNI@74030|Roseovarius	28211|Alphaproteobacteria	S	SCO1/SenC	-	-	-	-	-	-	-	-	-	-	-	-	SCO1-SenC
TLS2_k127_845937_0	1354722.JQLS01000008_gene2578	4.721e-96	333.0	COG2010@1|root,COG2010@2|Bacteria,1R4K1@1224|Proteobacteria,2VD1P@28211|Alphaproteobacteria,46PBI@74030|Roseovarius	28211|Alphaproteobacteria	CE	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS2_k127_853163_2	1218352.B597_018380	1.151e-27	115.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria,1Z1PC@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	P	COG0725 ABC-type molybdate transport system, periplasmic component	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
TLS2_k127_853163_1	1504672.669786642	3.715e-72	254.0	COG2005@1|root,COG2005@2|Bacteria,1P9SX@1224|Proteobacteria,2VMCH@28216|Betaproteobacteria,4ADJP@80864|Comamonadaceae	28216|Betaproteobacteria	K	transcriptional regulator, ModE family	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,TOBE
TLS2_k127_853163_0	1392838.AWNM01000025_gene4206	7.632e-234	729.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1QU9I@1224|Proteobacteria,2VHI0@28216|Betaproteobacteria,3T4WK@506|Alcaligenaceae	28216|Betaproteobacteria	L	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
TLS2_k127_876430_2	1265502.KB905932_gene1870	1.225e-21	94.0	COG0524@1|root,COG0524@2|Bacteria,1PDQE@1224|Proteobacteria,2VHMF@28216|Betaproteobacteria,4AB09@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM PfkB domain protein	adoK	-	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
TLS2_k127_876430_0	338969.Rfer_0204	8.105e-198	620.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,2VHGI@28216|Betaproteobacteria,4AC31@80864|Comamonadaceae	28216|Betaproteobacteria	G	Fructose-bisphosphate aldolase, class II, Calvin cycle subtype	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
TLS2_k127_876430_1	1454004.AW11_03827	4.48e-42	164.0	COG4585@1|root,COG4585@2|Bacteria,1R9XM@1224|Proteobacteria,2VR1U@28216|Betaproteobacteria,1KQ97@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	T	STAS-like domain of unknown function (DUF4325)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4325
TLS2_k127_890284_5	257310.BB0558	1.268e-11	65.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,2VJJQ@28216|Betaproteobacteria,3T3AX@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
TLS2_k127_890284_1	365044.Pnap_4121	4.519e-186	593.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,4ABQF@80864|Comamonadaceae	28216|Betaproteobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
TLS2_k127_890284_2	987059.RBXJA2T_13154	2.435e-118	385.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,2VIP5@28216|Betaproteobacteria,1KJZ0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	enoyl-CoA hydratase	fadB3	-	-	-	-	-	-	-	-	-	-	-	ECH_1
TLS2_k127_890284_7	420662.Mpe_A1435	0.0001754	45.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VIJ8@28216|Betaproteobacteria,1KJ4H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS2_k127_890284_4	795666.MW7_2671	1.056e-48	181.0	COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,2VU0N@28216|Betaproteobacteria,1K4I0@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
TLS2_k127_890284_0	365044.Pnap_0267	1.299e-302	934.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VMJK@28216|Betaproteobacteria,4AG8M@80864|Comamonadaceae	28216|Betaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
TLS2_k127_890284_3	395495.Lcho_3019	1.997e-49	189.0	2BXSN@1|root,32R1X@2|Bacteria,1MYVK@1224|Proteobacteria,2VYN9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF4243)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4243
TLS2_k127_890284_8	999541.bgla_2g28560	0.0006895	47.0	COG0789@1|root,COG0789@2|Bacteria,1RH2U@1224|Proteobacteria,2VSSK@28216|Betaproteobacteria,1KFPD@119060|Burkholderiaceae	28216|Betaproteobacteria	K	redox-sensitive transcriptional activator SoxR	soxR	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
TLS2_k127_937764_1	864051.BurJ1DRAFT_2100	5.996e-94	321.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2VHMQ@28216|Betaproteobacteria,1KJ78@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	endonuclease III	alkA	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
TLS2_k127_937764_0	864051.BurJ1DRAFT_2099	9.045e-220	696.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,1KJN4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
TLS2_k127_937764_4	987059.RBXJA2T_10459	4.286e-39	155.0	COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,1KKMD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_17,TPR_19,TPR_2,TPR_6,TPR_8
TLS2_k127_937764_3	983917.RGE_31660	1.177e-75	266.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ6F@28216|Betaproteobacteria,1KKPY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
TLS2_k127_937764_2	1538295.JY96_20655	4.703e-77	261.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,1KKMR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
TLS2_k127_937764_5	1121116.KB894776_gene1847	1.267e-27	113.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,2VHQY@28216|Betaproteobacteria,4A9K9@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	cysB	-	-	ko:K13634	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
TLS2_k127_95181_3	864051.BurJ1DRAFT_2650	8.081e-35	134.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2VIFN@28216|Betaproteobacteria,1KJQY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	FAD dependent oxidoreductase	ordL	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
TLS2_k127_95181_1	983917.RGE_26240	1.269e-120	396.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2VQGX@28216|Betaproteobacteria,1KJ70@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Peptidase C26	puuD	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
TLS2_k127_95181_0	420662.Mpe_A1901	2.411e-276	853.0	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,2VJHJ@28216|Betaproteobacteria,1KJKE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	glutamine synthetase	puuA2	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
TLS2_k127_95181_2	1538295.JY96_10445	2.394e-39	148.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VHST@28216|Betaproteobacteria,1KIYT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.113	ko:K12256	ko00330,ko01100,map00330,map01100	-	R08714	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
TLS2_k127_958218_0	987059.RBXJA2T_01605	9.622e-267	849.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2VIGF@28216|Betaproteobacteria,1KJF5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
TLS2_k127_958218_1	987059.RBXJA2T_01600	1.09e-113	377.0	COG4255@1|root,COG4255@2|Bacteria,1R59K@1224|Proteobacteria,2VKW9@28216|Betaproteobacteria,1KKNV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PhosphMutase
TLS2_k127_974438_0	983917.RGE_15860	3.586e-214	699.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VMZD@28216|Betaproteobacteria,1KK64@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_3
TLS2_k127_982539_0	864051.BurJ1DRAFT_4822	6.433e-196	617.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VH18@28216|Betaproteobacteria,1KJBT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Rieske 2Fe-2S	alcE	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
TLS2_k127_982539_1	864051.BurJ1DRAFT_4820	7.637e-50	183.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria,1KJDB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
TLS2_k127_998380_0	1485544.JQKP01000013_gene1796	4.228e-274	857.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,44VJW@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
## 2669 queries scanned
## Total time (seconds): 35.364644289016724
## Rate: 75.47 q/s